# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- ANAPC4_WD40 PF12894.7 CDJ55919.1 - 0.0024 18.2 0.0 0.009 16.3 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ55919.1 - 0.0028 18.4 0.1 0.0087 16.9 0.1 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat PD40 PF07676.12 CDJ55919.1 - 0.068 13.1 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat OmpH PF03938.14 CDJ55920.1 - 0.52 10.7 6.7 0.88 9.9 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dicistro_VP4 PF11492.8 CDJ55923.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Cricket paralysis virus, VP4 TGBp3 PF02495.17 CDJ55923.1 - 0.5 10.1 6.4 0.21 11.3 0.6 2.5 2 0 0 2 2 2 0 Triple gene block 3 DcuA_DcuB PF03605.14 CDJ55924.1 - 0.0082 15.1 1.1 0.011 14.6 1.1 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter Phage_holin_3_6 PF07332.11 CDJ55924.1 - 0.88 9.6 5.4 0.64 10.1 3.7 1.7 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3792 PF12670.7 CDJ55924.1 - 5.2 7.3 10.8 1 9.6 7.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) TPR_12 PF13424.6 CDJ55925.1 - 0.0008 19.6 1.0 0.0077 16.5 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ55925.1 - 0.0034 17.2 0.2 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ55925.1 - 0.026 14.6 2.1 0.074 13.2 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ55925.1 - 0.077 13.5 4.2 2.2 8.9 0.3 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat Ada3 PF10198.9 CDJ55926.1 - 0.017 15.2 5.7 0.024 14.8 5.7 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Phage_Mu_Gam PF07352.12 CDJ55926.1 - 0.022 14.7 5.2 0.023 14.6 4.5 1.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4618 PF15397.6 CDJ55926.1 - 0.022 14.2 11.7 0.029 13.8 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SpoU_sub_bind PF08032.12 CDJ55926.1 - 0.03 14.6 1.3 0.068 13.5 0.4 1.9 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding BOP1NT PF08145.12 CDJ55926.1 - 0.063 13.2 2.1 0.08 12.9 2.1 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain GlutR_dimer PF00745.20 CDJ55926.1 - 0.18 12.3 7.9 0.26 11.8 7.9 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain CtIP_N PF10482.9 CDJ55926.1 - 0.32 11.0 11.3 0.54 10.3 3.1 2.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 CDJ55926.1 - 0.77 10.2 18.5 0.64 10.5 7.1 2.7 1 1 1 2 2 2 0 Cell division protein ZapB USP8_interact PF08941.10 CDJ55926.1 - 0.85 9.4 8.0 0.13 12.1 3.5 1.7 1 1 1 2 2 2 0 USP8 interacting APG6_N PF17675.1 CDJ55926.1 - 2.4 8.7 14.6 3.9 8.0 14.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region GIT_CC PF16559.5 CDJ55926.1 - 2.9 7.8 10.5 2.9 7.8 0.2 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DSPc PF00782.20 CDJ55928.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain WD40 PF00400.32 CDJ55929.1 - 4.1e-09 36.9 11.8 0.00023 21.9 1.2 5.7 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ55929.1 - 0.00096 19.4 0.1 0.0076 16.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Crust_neurohorm PF01147.17 CDJ55929.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family CENP-F_leu_zip PF10473.9 CDJ55930.1 - 0.0063 16.5 5.1 0.0063 16.5 5.1 9.5 3 2 7 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 CDJ55932.1 - 0.2 11.4 4.5 0.32 10.8 3.0 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 CDJ55932.1 - 0.53 10.3 4.9 1.4 9.0 4.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CDJ55932.1 - 1.8 7.9 23.4 3.6 6.9 1.8 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 CDJ55932.1 - 2.4 7.9 6.4 1.1 9.0 1.7 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4326 PF14216.6 CDJ55932.1 - 3.1 8.6 4.7 1.8e+02 2.9 0.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4326) FTA4 PF13093.6 CDJ55932.1 - 3.3 7.5 11.5 3.3 7.6 9.1 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 WD40 PF00400.32 CDJ55934.1 - 0.14 13.1 2.7 16 6.6 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Dynein_C PF18199.1 CDJ55935.1 - 2.2e-82 276.8 0.0 1.5e-81 274.0 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDJ55935.1 - 1.6e-71 239.9 0.3 1.6e-71 239.9 0.3 1.9 2 0 0 2 2 1 1 ATP-binding dynein motor region MT PF12777.7 CDJ55935.1 - 1.6e-37 129.3 0.0 2.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ55935.1 - 8.3e-21 74.5 0.0 1.6e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain H-kinase_dim PF02895.14 CDJ55935.1 - 0.046 14.1 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain UPF0242 PF06785.11 CDJ55935.1 - 0.065 13.3 5.3 0.15 12.2 5.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 CDJ55935.1 - 0.084 12.9 11.5 0.15 12.2 8.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 CDJ55935.1 - 0.087 12.9 7.0 0.34 11.0 7.0 2.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L7Ae PF01248.26 CDJ55935.1 - 0.18 11.5 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TPR_3 PF07720.12 CDJ55935.1 - 0.18 11.8 0.3 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF812 PF05667.11 CDJ55935.1 - 0.25 10.2 5.6 0.082 11.8 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) COG2 PF06148.11 CDJ55935.1 - 0.76 9.9 7.1 2.3 8.3 3.4 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.12 CDJ55935.1 - 0.89 9.6 5.7 0.78 9.8 2.7 2.3 2 0 0 2 2 2 0 Laminin Domain II Atg14 PF10186.9 CDJ55935.1 - 4.6 6.2 6.5 6.4 5.8 5.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PCRF PF03462.18 CDJ55935.1 - 6 6.7 7.4 1.7 8.4 3.5 2.2 2 0 0 2 2 2 0 PCRF domain YscO-like PF16789.5 CDJ55935.1 - 7.5 6.6 13.0 4.1 7.4 5.0 2.4 2 0 0 2 2 2 0 YscO-like protein AAA_8 PF12780.7 CDJ55936.1 - 6.5e-70 235.4 0.0 9.5e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 CDJ55936.1 - 2e-09 37.0 7.7 3.1e-09 36.3 7.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CDJ55936.1 - 5.4e-08 33.0 0.5 1.5e-07 31.6 0.5 1.8 1 0 0 1 1 1 1 AAA+ lid domain HAP1_N PF04849.13 CDJ55936.1 - 0.0026 17.0 7.0 0.0052 16.0 7.0 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region VIT1 PF01988.19 CDJ55936.1 - 0.029 14.2 3.2 0.06 13.2 3.2 1.5 1 0 0 1 1 1 0 VIT family DUF2826 PF11442.8 CDJ55936.1 - 0.038 13.8 0.3 6.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) AAA_5 PF07728.14 CDJ55936.1 - 0.049 13.6 0.2 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Atg14 PF10186.9 CDJ55936.1 - 0.18 10.9 5.8 0.27 10.3 5.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CDJ55936.1 - 0.32 10.5 5.1 0.57 9.7 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CDJ55936.1 - 5.3 7.1 7.6 9.7 6.3 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 CDJ55936.1 - 8.8 6.5 7.7 12 6.0 1.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) AAA_6 PF12774.7 CDJ55937.1 - 2.3e-137 457.3 0.0 3.6e-137 456.7 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ55937.1 - 6.6e-109 364.6 7.4 6.6e-109 364.6 7.4 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ55937.1 - 1.8e-12 47.4 0.0 8e-05 22.7 0.0 4.1 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ55937.1 - 0.014 15.8 0.0 0.061 13.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDJ55937.1 - 0.035 13.6 0.4 2.7 7.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 CDJ55937.1 - 0.2 12.2 0.6 3.8 8.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CDJ55937.1 - 0.28 11.5 3.9 1.9 8.7 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 CDJ55937.1 - 9.3 6.6 7.7 7.9 6.8 0.0 4.4 4 1 1 5 5 5 0 AAA ATPase domain DHC_N1 PF08385.12 CDJ55938.1 - 9.9e-96 321.6 0.0 8.5e-83 278.9 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 L27 PF02828.16 CDJ55938.1 - 2.4 8.0 4.3 3.1 7.6 0.2 3.1 3 0 0 3 3 3 0 L27 domain zf-RING_7 PF02591.15 CDJ55939.1 - 0.17 12.1 0.8 9.2 6.6 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain NHL PF01436.21 CDJ55941.1 - 8.2e-13 47.7 0.6 0.089 12.9 0.1 6.6 7 0 0 7 7 7 4 NHL repeat Ephrin_rec_like PF07699.13 CDJ55941.1 - 0.0025 17.5 1.6 0.0025 17.5 1.6 5.7 4 1 1 5 5 5 3 Putative ephrin-receptor like DUF4748 PF15932.5 CDJ55942.1 - 1.1 9.1 0.0 1.1 9.1 0.0 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) DUF2299 PF10061.9 CDJ55942.1 - 2.6 7.8 7.3 0.25 11.1 1.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) Pkinase PF00069.25 CDJ55943.1 - 2.1e-36 125.7 0.0 1.6e-35 122.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ55943.1 - 3.7e-19 69.0 0.0 4.6e-14 52.3 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ55943.1 - 0.007 15.7 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ55943.1 - 0.0086 16.0 8.2 0.028 14.3 8.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_U4 PF03419.13 CDJ55944.1 - 0.67 9.2 5.3 1.2 8.4 5.3 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Apt1 PF10351.9 CDJ55944.1 - 3.1 6.5 32.0 0.011 14.7 14.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain GBP PF02263.19 CDJ55945.1 - 2.9e-21 75.9 0.2 2.9e-13 49.7 0.7 3.5 4 0 0 4 4 2 2 Guanylate-binding protein, N-terminal domain RskA PF10099.9 CDJ55945.1 - 7.9e-05 23.0 46.5 0.00036 20.9 0.0 5.9 4 2 1 5 5 4 3 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ55945.1 - 0.0041 18.0 1.6 0.0041 18.0 1.6 4.1 4 0 0 4 4 3 1 Domain of unknown function (DUF4834) OATP PF03137.20 CDJ55945.1 - 0.46 8.7 8.1 0.32 9.2 1.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ureide_permease PF07168.11 CDJ55945.1 - 0.77 8.5 5.3 1.3 7.7 0.2 2.7 2 0 0 2 2 2 0 Ureide permease Connexin PF00029.19 CDJ55945.1 - 1.2 8.8 13.4 0.11 12.3 0.6 3.0 3 0 0 3 3 3 0 Connexin MTABC_N PF16185.5 CDJ55945.1 - 1.8 8.0 6.8 1.4 8.3 0.6 2.6 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Folate_carrier PF01770.18 CDJ55945.1 - 2.3 6.9 9.0 0.57 8.9 2.0 2.6 2 0 0 2 2 2 0 Reduced folate carrier CSG2 PF16965.5 CDJ55945.1 - 4.8 6.0 10.7 0.12 11.2 0.6 2.7 3 0 0 3 3 3 0 Ceramide synthase regulator Peroxin-13_N PF04088.13 CDJ55945.1 - 6.1 7.1 13.1 5.9 7.2 2.3 3.9 3 0 0 3 3 3 0 Peroxin 13, N-terminal region DUF2723 PF11028.8 CDJ55945.1 - 6.6 6.6 8.3 0.53 10.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Fer4_14 PF13394.6 CDJ55945.1 - 7.2 6.8 6.4 6.5 6.9 1.7 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain SR-25 PF10500.9 CDJ55946.1 - 0.0031 17.2 5.0 0.0031 17.2 5.0 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ55946.1 - 0.67 10.4 11.4 0.78 10.2 6.2 2.1 1 1 0 2 2 2 0 AAA domain NPR3 PF03666.13 CDJ55946.1 - 2.7 6.7 23.0 0.33 9.7 14.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Transformer PF06495.11 CDJ55946.1 - 2.9 7.9 34.8 0.91 9.6 25.3 2.4 2 0 0 2 2 2 0 Fruit fly transformer protein SLBP_RNA_bind PF15247.6 CDJ55947.1 - 3.4e-18 65.5 0.9 3.4e-18 65.5 0.9 3.3 2 1 1 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain CPW_WPC PF09717.10 CDJ55948.1 - 2.8e-13 50.6 0.6 2.8e-13 50.6 0.6 3.0 2 2 1 3 3 3 1 Plasmodium falciparum domain of unknown function (CPW_WPC) Mit_KHE1 PF10173.9 CDJ55948.1 - 0.1 12.7 1.5 0.15 12.1 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3073 PF11273.8 CDJ55948.1 - 0.3 11.9 0.2 0.3 11.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) Sec62 PF03839.16 CDJ55948.1 - 2 7.9 4.3 3.3 7.2 4.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 CDJ55948.1 - 2.2 7.6 4.6 2.7 7.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RskA PF10099.9 CDJ55949.1 - 0.37 11.1 26.3 0.49 10.7 0.1 3.4 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ55949.1 - 1.1 8.8 19.2 1 8.9 8.0 2.6 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.9 CDJ55950.1 - 3.2e-05 22.7 29.3 3.2e-05 22.7 29.3 4.4 2 1 2 4 4 4 2 Macoilin family LpxI_N PF17930.1 CDJ55950.1 - 0.26 11.2 3.4 1.3 8.9 0.6 2.8 2 0 0 2 2 2 0 LpxI N-terminal domain Spt20 PF12090.8 CDJ55951.1 - 0.0029 17.3 11.2 0.0029 17.3 11.2 2.2 2 0 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ55951.1 - 0.0049 15.9 9.1 0.0049 15.9 9.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ55951.1 - 0.0074 15.3 14.2 0.0074 15.3 14.2 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 OmpH PF03938.14 CDJ55951.1 - 0.3 11.4 30.0 0.49 10.7 7.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3295 PF11702.8 CDJ55951.1 - 1.1 8.6 11.4 0.46 9.8 5.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) GET2 PF08690.10 CDJ55951.1 - 1.3 8.6 12.4 0.72 9.5 3.4 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Med15 PF09606.10 CDJ55951.1 - 2.3 6.8 40.7 3.5 6.2 40.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SMYLE_N PF18615.1 CDJ55951.1 - 2.7 7.4 11.1 5.2 6.5 2.0 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RskA PF10099.9 CDJ55953.1 - 7.1e-07 29.7 20.6 0.0098 16.2 0.0 3.8 1 1 2 3 3 3 1 Anti-sigma-K factor rskA RED_N PF07808.13 CDJ55953.1 - 0.14 11.7 0.0 0.14 11.7 0.0 3.7 3 1 0 3 3 3 0 RED-like protein N-terminal region Peptidase_M56 PF05569.11 CDJ55953.1 - 0.33 10.1 1.6 0.34 10.1 0.1 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 Phage_holin_2_1 PF04971.12 CDJ55953.1 - 2.7 8.1 5.3 1.9 8.6 1.5 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S CcdA PF07362.12 CDJ55953.1 - 6.3 7.3 11.2 0.92 10.0 1.4 3.6 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA PAP1 PF08601.10 CDJ55954.1 - 0.0003 20.7 5.2 0.0003 20.7 5.2 4.2 3 2 1 4 4 4 1 Transcription factor PAP1 RskA PF10099.9 CDJ55954.1 - 0.013 15.8 0.2 0.013 15.8 0.2 9.2 3 3 3 7 7 7 0 Anti-sigma-K factor rskA Nop25 PF09805.9 CDJ55955.1 - 0.011 16.2 3.1 0.011 16.2 3.1 7.5 4 2 2 6 6 6 0 Nucleolar protein 12 (25kDa) Glycogen_syn PF05693.13 CDJ55956.1 - 0.12 10.9 1.5 0.22 10.1 1.5 1.4 1 0 0 1 1 1 0 Glycogen synthase GTP_CH_N PF12471.8 CDJ55957.1 - 0.015 15.1 2.3 0.018 14.8 2.3 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal PAP2 PF01569.21 CDJ55957.1 - 0.037 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 PAP2 superfamily Phostensin_N PF13916.6 CDJ55957.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF2681 PF10883.8 CDJ55957.1 - 1.9 9.0 19.9 4.9 7.6 8.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2981 PF11200.8 CDJ55957.1 - 3.5 7.3 11.1 4.2 7.0 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF5345 PF17280.2 CDJ55957.1 - 4.1 7.4 14.3 3.4 7.7 6.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) SPATIAL PF15256.6 CDJ55957.1 - 4.6 7.5 15.6 4.3 7.6 3.9 2.0 1 1 1 2 2 2 0 SPATIAL C6 PF01681.17 CDJ55957.1 - 5.5 7.6 14.5 1.4e+02 3.1 14.5 2.3 1 1 0 1 1 1 0 C6 domain Ndc1_Nup PF09531.10 CDJ55957.1 - 6.1 5.4 18.3 7 5.2 18.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CDJ55957.1 - 6.9 5.1 16.4 8.6 4.8 16.4 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ55959.1 - 0.0021 18.0 13.7 0.003 17.6 13.7 1.3 1 0 0 1 1 1 1 SPX domain Paramyxo_ncap PF00973.19 CDJ55959.1 - 0.69 8.8 6.3 1 8.2 6.3 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Striatin PF08232.12 CDJ55959.1 - 8.7 6.9 18.5 1.2 9.7 11.1 2.2 2 0 0 2 2 2 0 Striatin family DUF4834 PF16118.5 CDJ55962.1 - 0.01 16.8 2.0 0.02 15.8 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FHIPEP PF00771.20 CDJ55962.1 - 0.014 13.9 2.0 0.011 14.2 1.0 1.4 1 1 0 1 1 1 0 FHIPEP family Laminin_II PF06009.12 CDJ55962.1 - 0.026 14.5 1.8 0.026 14.5 1.8 2.9 2 1 1 3 3 3 0 Laminin Domain II Presenilin PF01080.17 CDJ55962.1 - 0.29 9.8 2.6 0.29 9.9 2.6 1.1 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 CDJ55962.1 - 0.52 8.9 19.1 0.031 13.0 13.5 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ55962.1 - 8.7 5.9 25.5 1.6 8.3 20.5 1.9 2 0 0 2 2 2 0 Spt20 family DDHD PF02862.17 CDJ55962.1 - 9.3 6.3 8.4 14 5.7 8.4 1.4 1 1 0 1 1 1 0 DDHD domain zf-CCCH PF00642.24 CDJ55963.1 - 3.1e-09 36.5 20.6 5.6e-06 26.1 2.9 3.6 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ55963.1 - 2.6e-07 30.3 2.5 2.6e-07 30.3 2.5 3.5 4 1 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ55963.1 - 1.6e-05 24.8 4.4 1.6e-05 24.8 4.4 4.4 5 0 0 5 5 5 1 Zinc finger domain zf-C3H1 PF10650.9 CDJ55963.1 - 0.00061 19.5 9.0 0.91 9.3 0.5 3.6 3 0 0 3 3 3 3 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDJ55963.1 - 0.0019 18.6 16.1 0.11 13.0 2.4 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDJ55963.1 - 0.035 14.8 12.3 0.048 14.4 1.6 3.1 1 1 2 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 CDJ55963.1 - 0.15 12.3 5.8 0.52 10.5 2.3 2.4 2 0 0 2 2 2 0 Zinc-finger containing family ASFV_J13L PF05568.11 CDJ55963.1 - 1.9 8.2 7.2 2.8 7.7 4.0 2.0 1 1 1 2 2 2 0 African swine fever virus J13L protein S10_plectin PF03501.15 CDJ55964.1 - 2.6e-39 133.2 0.3 3.2e-39 132.9 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain EELM2 PF15863.5 CDJ55965.1 - 1.6e-62 210.7 0.0 2.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain DUF2318 PF10080.9 CDJ55965.1 - 0.028 14.5 0.7 0.049 13.8 0.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Macoilin PF09726.9 CDJ55965.1 - 0.53 8.8 2.9 0.57 8.7 2.9 1.2 1 0 0 1 1 1 0 Macoilin family OrfB_Zn_ribbon PF07282.11 CDJ55965.1 - 0.63 10.0 3.3 1.5 8.8 3.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain TPR_MLP1_2 PF07926.12 CDJ55966.1 - 0.0015 18.6 12.5 0.0015 18.6 12.5 6.3 2 1 5 7 7 7 1 TPR/MLP1/MLP2-like protein zf-C2HC_2 PF13913.6 CDJ55969.1 - 4e-07 29.8 2.1 4e-07 29.8 2.1 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CDJ55969.1 - 0.035 14.4 1.4 0.098 13.0 1.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDJ55969.1 - 0.12 13.3 3.1 0.24 12.3 2.4 2.0 1 1 1 2 2 2 0 C2H2-type zinc finger Peptidase_S9_N PF02897.15 CDJ55970.1 - 1.9e-107 359.6 0.1 2.6e-107 359.2 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CDJ55970.1 - 1.9e-56 190.9 0.0 3.1e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ55970.1 - 0.068 12.8 0.1 0.89 9.1 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF4227 PF14004.6 CDJ55970.1 - 0.077 13.0 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) BAAT_C PF08840.11 CDJ55970.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CDJ55971.1 - 3.6e-06 26.6 0.1 0.014 14.9 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ55971.1 - 4.3e-06 26.6 0.1 0.00011 21.9 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ55971.1 - 4.7e-06 26.0 0.2 0.00022 20.5 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 CDJ55971.1 - 1.4e-05 24.8 0.0 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CDJ55971.1 - 0.00023 21.9 0.0 0.00036 21.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.11 CDJ55971.1 - 0.0021 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PhoPQ_related PF10142.9 CDJ55971.1 - 0.063 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Pyr_redox_2 PF07992.14 CDJ55972.1 - 5.7e-71 239.1 4.5 8.3e-71 238.6 4.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ55972.1 - 3.5e-36 123.8 0.0 7.7e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ55972.1 - 1.4e-22 80.1 6.3 1.8e-19 70.1 0.5 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ55972.1 - 9.5e-12 45.0 0.5 1.9e-10 40.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CDJ55972.1 - 5.2e-09 35.7 1.7 5.2e-09 35.7 1.7 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CDJ55972.1 - 3.1e-07 30.0 1.6 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ55972.1 - 2.2e-06 27.0 3.9 2.2e-06 27.0 3.9 2.4 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 CDJ55972.1 - 1.2e-05 24.7 0.7 0.11 11.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CDJ55972.1 - 1.2e-05 24.2 9.2 0.00096 17.9 0.2 3.9 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 CDJ55972.1 - 1.3e-05 25.3 6.6 0.00042 20.5 1.7 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CDJ55972.1 - 0.00019 20.8 9.7 0.048 12.9 0.9 3.1 2 1 0 3 3 3 3 FAD binding domain Thi4 PF01946.17 CDJ55972.1 - 0.0002 20.7 0.1 0.0007 18.9 0.1 1.9 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 CDJ55972.1 - 0.00072 18.9 3.7 0.038 13.3 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDJ55972.1 - 0.00089 18.9 10.8 0.87 9.1 0.1 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CDJ55972.1 - 0.025 14.5 0.2 0.025 14.5 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CDJ55972.1 - 0.077 13.5 0.2 30 5.1 0.1 2.8 2 1 1 3 3 3 0 XdhC Rossmann domain Glyco_transf_43 PF03360.16 CDJ55974.1 - 0.17 11.7 0.3 0.31 10.8 0.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 43 Exonuc_VII_L PF02601.15 CDJ55974.1 - 0.28 10.7 3.9 0.45 10.0 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 CDJ55974.1 - 0.41 10.4 14.0 0.67 9.7 14.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family C2 PF00168.30 CDJ55975.1 - 9.4e-34 115.8 0.2 5.5e-06 26.6 0.0 6.5 6 0 0 6 6 6 6 C2 domain Ferlin_C PF16165.5 CDJ55975.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Macoilin PF09726.9 CDJ55976.1 - 8.2 4.8 11.2 10 4.5 11.2 1.1 1 0 0 1 1 1 0 Macoilin family Ephrin_rec_like PF07699.13 CDJ55978.1 - 3.8e-07 29.8 32.4 8.6e-06 25.4 7.5 4.7 4 1 1 5 5 5 3 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 CDJ55978.1 - 0.00034 20.7 0.1 0.001 19.2 0.1 1.8 1 0 0 1 1 1 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 EGF_MSP1_1 PF12946.7 CDJ55978.1 - 0.5 10.5 9.1 0.37 10.9 1.9 4.0 3 1 0 3 3 3 0 MSP1 EGF domain 1 DAGK_prokar PF01219.19 CDJ55980.1 - 0.25 11.2 2.5 1 9.2 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase Carb_anhydrase PF00194.21 CDJ55981.1 - 5.6e-15 55.6 9.4 4.9e-07 29.5 0.0 3.7 1 1 0 3 3 3 3 Eukaryotic-type carbonic anhydrase DUF4207 PF13904.6 CDJ55981.1 - 0.003 17.3 21.0 0.003 17.3 21.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4207) RskA PF10099.9 CDJ55981.1 - 0.0071 16.7 4.4 0.0071 16.7 4.4 3.9 1 1 2 3 3 3 1 Anti-sigma-K factor rskA SOBP PF15279.6 CDJ55981.1 - 0.042 14.5 32.3 0.36 11.4 16.6 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein RED_N PF07808.13 CDJ55981.1 - 0.38 10.3 19.2 0.16 11.5 2.6 2.6 2 0 0 2 2 2 0 RED-like protein N-terminal region Thg1C PF14413.6 CDJ55981.1 - 0.52 10.5 9.2 6.6 6.9 3.1 2.7 2 0 0 2 2 2 0 Thg1 C terminal domain EIF4E-T PF10477.9 CDJ55981.1 - 1.9 7.2 36.3 2 7.1 16.1 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Paf1 PF03985.13 CDJ55981.1 - 5.3 5.9 17.0 1.1 8.2 6.1 2.6 2 0 0 2 2 2 0 Paf1 FHIPEP PF00771.20 CDJ55981.1 - 6 5.2 13.2 1.2 7.5 2.6 2.2 2 0 0 2 2 2 0 FHIPEP family FAM199X PF15814.5 CDJ55981.1 - 8.4 5.3 36.8 0.44 9.6 1.7 2.6 2 1 0 2 2 2 0 Protein family FAM199X Robl_LC7 PF03259.17 CDJ55982.1 - 0.029 14.1 0.5 0.042 13.6 0.5 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain Porin_4 PF13609.6 CDJ55982.1 - 0.031 14.1 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 Gram-negative porin MPP6 PF10175.9 CDJ55982.1 - 0.053 14.0 10.5 0.078 13.5 10.5 1.2 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Ribosomal_60s PF00428.19 CDJ55982.1 - 0.057 14.0 6.1 0.057 14.0 6.1 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ55982.1 - 0.098 12.9 19.7 0.31 11.3 2.6 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Ilar_coat PF01787.16 CDJ55982.1 - 0.13 12.0 1.8 0.17 11.6 1.8 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein CbiD PF01888.17 CDJ55982.1 - 0.15 11.4 1.4 0.35 10.1 0.2 1.9 2 0 0 2 2 2 0 CbiD Nop14 PF04147.12 CDJ55982.1 - 0.31 9.2 15.8 0.37 8.9 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 CDJ55982.1 - 0.59 9.7 12.1 0.76 9.3 12.1 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3138 PF11336.8 CDJ55982.1 - 0.62 8.6 7.6 0.74 8.4 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Nucleo_P87 PF07267.11 CDJ55982.1 - 1.2 7.9 10.9 1.4 7.7 10.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BSP_II PF05432.11 CDJ55982.1 - 3.9 7.1 23.0 0.51 10.0 18.0 1.7 1 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF5327 PF17261.2 CDJ55983.1 - 0.0088 16.8 40.4 0.023 15.4 13.8 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5327) DUF3499 PF12005.8 CDJ55983.1 - 0.97 10.0 22.0 0.73 10.4 7.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) DUF1631 PF07793.11 CDJ55983.1 - 1.3 7.4 47.9 1.7 7.0 47.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FHIPEP PF00771.20 CDJ55983.1 - 1.3 7.4 15.0 0.63 8.4 1.1 2.1 2 0 0 2 2 2 0 FHIPEP family UPF0240 PF06784.11 CDJ55983.1 - 9.2 6.3 23.6 6.2 6.9 5.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) RNA_pol_Rbc25 PF08292.12 CDJ55983.1 - 9.6 6.5 22.9 0.21 11.8 5.1 3.3 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 Herpes_UL52 PF03121.15 CDJ55985.1 - 0.00036 20.4 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase MID_MedPIWI PF18296.1 CDJ55985.1 - 0.51 10.1 0.0 0.51 10.1 0.0 7.7 6 1 1 7 7 7 0 MID domain of medPIWI LSM14 PF12701.7 CDJ55986.1 - 1.8e-23 82.4 0.0 2.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDJ55986.1 - 8.9e-06 26.5 2.8 0.17 12.8 0.0 2.3 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.6 CDJ55986.1 - 4.5e-05 23.5 0.0 7.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 CDJ55987.1 - 0.011 15.7 0.1 0.77 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CSN5_C PF18323.1 CDJ55987.1 - 0.057 14.3 0.3 0.14 13.1 0.1 1.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Mito_carr PF00153.27 CDJ55988.1 - 4.1e-30 103.6 0.7 4.6e-15 55.3 0.1 2.6 2 1 1 3 3 3 2 Mitochondrial carrier protein ATF7IP_BD PF16788.5 CDJ55989.1 - 0.013 15.7 0.6 0.013 15.7 0.6 2.4 3 0 0 3 3 3 0 ATF-interacting protein binding domain DUF3439 PF11921.8 CDJ55989.1 - 3.8 7.5 9.4 52 3.8 6.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) T2SSF PF00482.23 CDJ55989.1 - 4.5 7.2 7.8 22 5.0 0.0 3.7 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F FlaC_arch PF05377.11 CDJ55989.1 - 7.2 7.1 7.0 22 5.6 0.2 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MFS_1 PF07690.16 CDJ55990.1 - 0.00032 19.7 30.8 0.0033 16.4 16.2 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDJ55990.1 - 0.00061 18.5 2.8 0.00061 18.5 2.8 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 CDJ55990.1 - 0.043 12.1 0.0 0.043 12.1 0.0 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ55990.1 - 0.15 12.1 11.9 0.049 13.6 3.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 CDJ55991.1 - 8.5e-28 97.2 0.0 3e-15 56.0 0.0 4.2 4 1 0 4 4 4 3 Kinesin motor domain Microtub_bd PF16796.5 CDJ55991.1 - 1.2e-06 28.5 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Apt1 PF10351.9 CDJ55991.1 - 0.87 8.4 4.8 1.6 7.5 0.5 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Spt20 PF12090.8 CDJ55991.1 - 2.1 7.9 20.8 0.054 13.1 12.9 2.2 2 0 0 2 2 2 0 Spt20 family Tim54 PF11711.8 CDJ55991.1 - 4.6 5.9 8.7 0.12 11.1 1.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PolyA_pol PF01743.20 CDJ55992.1 - 5.7e-06 26.8 1.9 1.2e-05 25.7 0.0 2.6 3 0 0 3 3 3 1 Poly A polymerase head domain Spt20 PF12090.8 CDJ55992.1 - 0.0031 17.2 6.7 0.0031 17.2 6.7 4.1 3 1 0 3 3 3 1 Spt20 family Mem_trans PF03547.18 CDJ55992.1 - 0.57 8.5 4.9 0.087 11.2 1.0 1.7 2 0 0 2 2 2 0 Membrane transport protein TFIIA PF03153.13 CDJ55993.1 - 0.11 12.4 54.1 0.085 12.8 17.7 4.2 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 CDJ55995.1 - 9.4e-92 308.2 2.4 2.7e-89 300.0 2.4 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mannitol_dh_C PF08125.13 CDJ55996.1 - 1.9e-13 50.5 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 CDJ55996.1 - 0.037 14.2 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain AFG1_ATPase PF03969.16 CDJ55997.1 - 1.2e-36 126.4 0.1 1.4e-36 126.2 0.1 1.3 1 1 0 1 1 1 1 AFG1-like ATPase TniB PF05621.11 CDJ55997.1 - 0.012 15.0 0.0 0.16 11.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 CDJ55997.1 - 0.05 13.9 0.1 3.3 8.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CDJ55997.1 - 0.055 13.3 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein AAA PF00004.29 CDJ55997.1 - 0.083 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CDJ55997.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Clp_N PF02861.20 CDJ55998.1 - 0.017 15.3 0.1 3.2 7.9 0.2 2.6 2 1 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component DUF4244 PF14029.6 CDJ55998.1 - 0.13 11.7 0.3 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) YppG PF14179.6 CDJ55999.1 - 0.036 14.8 4.0 0.036 14.8 4.0 2.7 3 0 0 3 3 3 0 YppG-like protein Spt20 PF12090.8 CDJ55999.1 - 2 8.0 10.5 0.04 13.5 2.4 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ55999.1 - 4.2 7.3 11.5 0.23 11.4 1.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Musclin PF11037.8 CDJ56000.1 - 0.23 11.4 2.5 2.4 8.1 0.0 2.9 2 0 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle Conotoxin PF02950.17 CDJ56000.1 - 0.86 10.7 0.1 0.86 10.7 0.1 5.6 7 2 0 7 7 7 0 Conotoxin Peptidase_S49_N PF08496.10 CDJ56000.1 - 3.2 7.8 11.6 6.4 6.8 0.7 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal PIG-S PF10510.9 CDJ56002.1 - 8.4 5.1 13.5 18 4.0 13.5 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein BAF1_ABF1 PF04684.13 CDJ56002.1 - 9.4 5.2 31.1 0.57 9.2 22.5 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3439 PF11921.8 CDJ56005.1 - 0.59 10.1 6.3 0.82 9.6 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) SLC12 PF03522.15 CDJ56005.1 - 9.6 5.1 68.5 2.1 7.3 5.1 3.2 3 0 0 3 3 3 0 Solute carrier family 12 SHNi-TPR PF10516.9 CDJ56006.1 - 5.1e-05 22.6 0.2 0.00024 20.5 0.0 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 CDJ56006.1 - 0.00024 21.0 0.2 1.5 9.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56006.1 - 0.025 14.4 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LMBR1 PF04791.16 CDJ56006.1 - 3.3 6.5 7.8 4.7 6.0 7.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BORG_CEP PF14957.6 CDJ56006.1 - 4.3 8.5 20.7 6.9 7.8 10.8 3.4 3 0 0 3 3 3 0 Cdc42 effector OATP PF03137.20 CDJ56006.1 - 8.4 4.5 8.6 2.2 6.5 3.6 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AAA_23 PF13476.6 CDJ56007.1 - 0.21 12.1 9.8 0.083 13.4 3.1 2.5 2 0 0 2 2 2 0 AAA domain Spore_YhcN_YlaJ PF09580.10 CDJ56007.1 - 0.71 9.9 12.0 0.59 10.2 5.7 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF755 PF05501.11 CDJ56008.1 - 0.002 18.4 9.7 0.002 18.4 9.7 8.1 7 3 1 8 8 8 1 Domain of unknown function (DUF755) SPX PF03105.19 CDJ56008.1 - 0.054 13.4 31.1 1.8e+04 -8.7 31.1 3.6 1 1 0 1 1 1 0 SPX domain DnaJ PF00226.31 CDJ56009.1 - 4.9e-15 55.4 3.1 1.5e-14 53.8 3.1 1.9 1 0 0 1 1 1 1 DnaJ domain DUF966 PF06136.13 CDJ56010.1 - 6.1 6.5 33.0 8.4 6.0 33.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MCU PF04678.13 CDJ56011.1 - 0.005 16.9 0.2 0.005 16.9 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 CDJ56011.1 - 0.008 15.8 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Ten_N PF06484.12 CDJ56011.1 - 0.013 15.5 2.5 0.018 14.9 2.5 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region Metal_resist PF13801.6 CDJ56011.1 - 0.024 14.8 0.5 0.024 14.8 0.5 2.9 3 0 0 3 3 3 0 Heavy-metal resistance MctB PF11382.8 CDJ56011.1 - 0.056 13.1 3.5 0.13 11.9 3.4 1.6 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF2722 PF10846.8 CDJ56011.1 - 0.057 12.4 9.2 0.092 11.7 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NUDE_C PF04880.13 CDJ56011.1 - 0.071 13.6 4.3 0.1 13.1 3.0 1.9 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region GPHR_N PF12537.8 CDJ56011.1 - 0.14 12.3 0.2 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF4407 PF14362.6 CDJ56011.1 - 0.15 11.4 4.6 0.19 11.1 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM199X PF15814.5 CDJ56011.1 - 0.32 10.0 3.8 0.46 9.5 3.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF4175 PF13779.6 CDJ56011.1 - 0.43 8.4 15.1 0.59 8.0 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIF4E-T PF10477.9 CDJ56011.1 - 0.49 9.1 8.2 0.65 8.8 8.2 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1043 PF06295.12 CDJ56011.1 - 0.55 10.2 13.3 27 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) EMP24_GP25L PF01105.24 CDJ56011.1 - 2.1 8.2 4.9 0.2 11.6 0.3 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 CDJ56011.1 - 3.8 7.3 17.1 2.7 7.8 14.6 1.9 2 0 0 2 2 2 0 Septum formation initiator BBS2_C PF14782.6 CDJ56011.1 - 4.2 6.0 7.2 6.2 5.5 7.2 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Spc24 PF08286.11 CDJ56011.1 - 4.8 7.5 9.3 11 6.4 9.3 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Herpes_UL32 PF06070.11 CDJ56011.1 - 8.4 4.0 8.1 13 3.4 8.1 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF2802 PF10975.8 CDJ56011.1 - 8.6 6.6 22.5 14 5.8 20.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF4140 PF13600.6 CDJ56011.1 - 9.1 6.8 9.2 1.1 9.7 4.6 1.8 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) PET117 PF15786.5 CDJ56012.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.7 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial ANAPC15 PF15243.6 CDJ56012.1 - 1.1 9.7 11.6 0.085 13.3 3.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Peptidase_M17_N PF02789.17 CDJ56012.1 - 1.2 9.0 9.8 0.08 12.8 2.4 2.2 1 1 2 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain GREB1 PF15782.5 CDJ56012.1 - 8.2 3.4 21.2 9.7 3.1 21.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ntox11 PF15521.6 CDJ56013.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Novel toxin 11 Bac_rhamnosid6H PF17389.2 CDJ56013.1 - 0.17 11.1 1.7 0.17 11.1 0.6 1.6 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Spt20 PF12090.8 CDJ56013.1 - 0.7 9.5 12.2 0.39 10.3 2.6 2.4 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ56014.1 - 9.4e-09 35.2 53.1 0.0051 16.5 13.1 4.0 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein LMBR1 PF04791.16 CDJ56014.1 - 0.19 10.6 6.7 1.4 7.7 1.9 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein Hydrolase_4 PF12146.8 CDJ56015.1 - 9.8e-14 51.2 1.8 1.4e-10 40.9 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ56015.1 - 3.7e-07 31.0 5.5 3.7e-07 31.0 5.5 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ56015.1 - 0.00014 21.6 7.1 0.00015 21.5 0.2 3.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 CDJ56015.1 - 0.0017 18.0 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family UIM PF02809.20 CDJ56015.1 - 0.016 15.1 0.6 0.036 14.0 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif FSH1 PF03959.13 CDJ56015.1 - 0.034 13.8 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Macoilin PF09726.9 CDJ56015.1 - 0.1 11.1 16.5 0.16 10.5 16.5 1.3 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CDJ56015.1 - 0.65 9.9 19.8 0.93 9.3 19.8 1.2 1 0 0 1 1 1 0 SPX domain Plasmodium_Vir PF05795.11 CDJ56015.1 - 0.69 9.3 6.7 1 8.7 6.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RskA PF10099.9 CDJ56015.1 - 1.4 9.2 46.6 0.39 11.0 10.2 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Noc2 PF03715.13 CDJ56016.1 - 1.7e-16 60.3 0.0 4.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Noc2p family Macoilin PF09726.9 CDJ56016.1 - 0.00078 18.1 34.7 0.00078 18.1 34.7 3.7 3 1 0 3 3 3 1 Macoilin family KH_1 PF00013.29 CDJ56017.1 - 8.8e-16 57.5 0.0 4.7e-05 23.1 0.0 5.0 5 0 0 5 5 5 3 KH domain PaaB PF06243.11 CDJ56019.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Phenylacetic acid degradation B HAD_SAK_2 PF18143.1 CDJ56020.1 - 0.48 10.7 2.0 0.66 10.3 0.6 2.0 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Activator_LAG-3 PF11498.8 CDJ56022.1 - 0.0016 17.5 7.7 0.0016 17.5 7.7 4.4 4 0 0 4 4 4 2 Transcriptional activator LAG-3 DUF4471 PF14740.6 CDJ56022.1 - 0.029 13.6 0.3 0.029 13.6 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4471) DUF2971 PF11185.8 CDJ56022.1 - 1.9 9.7 4.7 9.1 7.5 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2971) DUF2058 PF09831.9 CDJ56023.1 - 0.015 15.5 6.6 0.015 15.5 6.6 3.8 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2058) Ribosomal_S10 PF00338.22 CDJ56024.1 - 3.7e-07 30.3 0.6 3.7e-07 30.3 0.6 2.6 2 2 0 2 2 2 1 Ribosomal protein S10p/S20e Spt20 PF12090.8 CDJ56024.1 - 0.0035 17.0 12.1 0.0035 17.0 12.1 3.2 2 1 1 3 3 3 1 Spt20 family Amidase PF01425.21 CDJ56024.1 - 0.19 10.6 1.1 0.31 10.0 1.1 1.3 1 0 0 1 1 1 0 Amidase RNA_pol_Rpc4 PF05132.14 CDJ56025.1 - 2.1e-17 63.9 0.1 2.1e-17 63.9 0.1 5.5 4 2 2 6 6 6 1 RNA polymerase III RPC4 SR-25 PF10500.9 CDJ56025.1 - 0.0038 16.9 3.3 0.0038 16.9 3.3 4.8 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein ATP_transf PF09830.9 CDJ56025.1 - 0.15 12.2 0.1 0.82 9.9 0.1 2.3 1 0 0 1 1 1 0 ATP adenylyltransferase Diphthamide_syn PF01866.17 CDJ56026.1 - 1.7e-31 109.8 0.0 2.3e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein RBM39linker PF15519.6 CDJ56026.1 - 4.8 8.3 8.4 11 7.2 8.4 1.5 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF2722 PF10846.8 CDJ56030.1 - 0.00076 18.5 1.8 0.00076 18.5 1.8 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ56030.1 - 0.0019 17.9 8.9 0.0019 17.9 8.9 3.4 3 0 0 3 3 3 2 Spt20 family TraT PF05818.12 CDJ56030.1 - 0.0091 15.7 5.0 0.0091 15.7 5.0 3.9 4 1 0 4 4 4 1 Enterobacterial TraT complement resistance protein Ribosomal_60s PF00428.19 CDJ56030.1 - 0.01 16.4 7.9 0.01 16.4 7.9 6.4 5 1 0 5 5 5 0 60s Acidic ribosomal protein Lin-8 PF03353.15 CDJ56030.1 - 0.19 11.3 22.6 0.12 11.9 5.5 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ56030.1 - 0.31 11.3 71.6 0.14 12.5 19.5 3.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4820 PF16091.5 CDJ56030.1 - 0.44 9.9 25.4 0.4 10.0 1.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) Med15 PF09606.10 CDJ56030.1 - 0.89 8.2 56.5 0.4 9.3 11.7 3.4 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal RSRP PF17069.5 CDJ56030.1 - 2 7.9 23.6 5.9 6.4 17.6 2.5 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 eIF-3_zeta PF05091.12 CDJ56030.1 - 6.4 5.6 25.2 0.85 8.5 2.7 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) KHA PF11834.8 CDJ56031.1 - 0.16 12.0 0.5 22 5.2 0.0 3.6 3 0 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel DUF2722 PF10846.8 CDJ56032.1 - 7.6e-05 21.8 0.0 7.6e-05 21.8 0.0 2.4 1 1 0 2 2 1 1 Protein of unknown function (DUF2722) Mito_carr PF00153.27 CDJ56032.1 - 0.00059 19.7 0.2 0.0031 17.4 0.2 2.3 1 1 0 1 1 1 1 Mitochondrial carrier protein SR-25 PF10500.9 CDJ56032.1 - 0.001 18.7 7.0 0.002 17.8 2.1 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CDJ56032.1 - 0.0038 17.9 1.8 0.0038 17.9 1.8 2.2 2 0 0 2 2 2 1 Immortalisation up-regulated protein DUF4050 PF13259.6 CDJ56032.1 - 0.026 14.9 5.5 2.6 8.3 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) CCSAP PF15748.5 CDJ56032.1 - 0.036 14.3 1.2 0.036 14.3 1.2 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF3446 PF11928.8 CDJ56032.1 - 0.11 12.8 10.7 0.11 12.7 3.8 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF775 PF05603.12 CDJ56032.1 - 0.62 9.6 5.3 6.1 6.3 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) EPL1 PF10513.9 CDJ56032.1 - 0.64 10.4 10.2 3.5 8.0 1.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like FTO_NTD PF12933.7 CDJ56032.1 - 2.1 7.5 5.2 0.44 9.7 0.1 2.0 2 0 0 2 2 2 0 FTO catalytic domain Suf PF05843.14 CDJ56032.1 - 2.7 7.9 10.8 8.3 6.3 3.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ56032.1 - 3.1 6.4 23.6 0.89 8.2 3.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ly49 PF08391.10 CDJ56032.1 - 5.4 7.4 0.0 5.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region EF-hand_1 PF00036.32 CDJ56033.1 - 7.3e-13 47.1 1.6 0.00021 20.6 0.1 3.8 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ56033.1 - 3.1e-10 40.4 0.8 2.3e-07 31.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ56033.1 - 3.7e-10 38.9 1.2 0.00042 20.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ56033.1 - 3.3e-06 26.4 0.2 0.043 13.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ56033.1 - 3.4e-05 23.6 0.8 0.00029 20.6 0.2 2.5 1 1 2 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ56033.1 - 0.00076 19.8 7.8 0.0031 17.8 0.1 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SUIM_assoc PF16619.5 CDJ56033.1 - 0.0011 19.0 26.8 16 5.7 22.8 2.9 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_4 PF12763.7 CDJ56033.1 - 0.0086 16.0 0.2 0.043 13.8 0.1 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand eIF-3_zeta PF05091.12 CDJ56033.1 - 0.017 14.1 12.3 0.022 13.7 12.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Macoilin PF09726.9 CDJ56033.1 - 0.02 13.5 15.1 0.027 13.0 15.1 1.2 1 0 0 1 1 1 0 Macoilin family NST1 PF13945.6 CDJ56033.1 - 0.14 12.3 20.2 0.23 11.5 20.2 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Mitofilin PF09731.9 CDJ56033.1 - 0.17 10.7 40.5 0.23 10.3 40.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4638 PF15472.6 CDJ56033.1 - 0.2 11.4 10.0 0.28 10.9 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Folate_carrier PF01770.18 CDJ56033.1 - 0.2 10.4 2.2 0.28 9.9 2.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF4770 PF15994.5 CDJ56033.1 - 0.3 11.3 10.5 0.5 10.6 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SID-1_RNA_chan PF13965.6 CDJ56033.1 - 0.39 9.1 2.6 0.39 9.1 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMR1 PF08505.10 CDJ56033.1 - 0.45 10.8 19.4 0.86 9.8 19.4 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Asp-B-Hydro_N PF05279.11 CDJ56033.1 - 0.46 10.5 22.0 0.61 10.1 22.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RLL PF10036.9 CDJ56033.1 - 0.55 10.0 20.6 0.85 9.4 20.6 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein V_ATPase_I PF01496.19 CDJ56033.1 - 1.1 7.2 11.6 1.3 6.8 11.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CDJ56033.1 - 1.4 7.7 4.2 1.4 7.7 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4647 PF15504.6 CDJ56033.1 - 1.5 7.8 18.5 2.1 7.3 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Stevor PF17410.2 CDJ56033.1 - 2 7.9 5.1 2.9 7.4 5.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SOBP PF15279.6 CDJ56033.1 - 2.5 8.6 21.8 3.2 8.3 21.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SLC12 PF03522.15 CDJ56033.1 - 7.8 5.4 18.0 11 5.0 18.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ56033.1 - 8.1 5.4 9.3 11 5.0 9.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein SWI-SNF_Ssr4 PF08549.10 CDJ56033.1 - 8.8 4.8 34.7 12 4.4 34.7 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GREB1 PF15782.5 CDJ56033.1 - 9 3.3 23.6 11 3.0 23.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer OATP PF03137.20 CDJ56033.1 - 9.4 4.4 7.0 13 3.9 7.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4667 PF15700.5 CDJ56034.1 - 0.0065 16.6 1.3 0.0065 16.6 1.3 5.5 2 1 2 4 4 4 1 Domain of unknown function (DUF4667) Apt1 PF10351.9 CDJ56034.1 - 0.63 8.8 0.0 0.63 8.8 0.0 4.4 2 2 0 3 3 3 0 Golgi-body localisation protein domain TFIIA PF03153.13 CDJ56036.1 - 0.003 17.6 16.5 0.003 17.6 16.5 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit ATP-synt_ab_N PF02874.23 CDJ56037.1 - 1.6e-14 54.1 0.7 1.6e-14 54.1 0.7 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 CDJ56037.1 - 3.6e-07 30.0 0.1 5.1e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HAS-barrel PF09378.10 CDJ56037.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 HAS barrel domain Bac_luciferase PF00296.20 CDJ56038.1 - 0.055 12.9 5.8 0.067 12.6 5.8 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase eIF-3_zeta PF05091.12 CDJ56038.1 - 0.056 12.4 8.8 0.061 12.3 8.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ56038.1 - 0.073 13.0 14.2 0.09 12.8 14.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.13 CDJ56038.1 - 0.079 12.0 8.7 0.086 11.9 8.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CAF1 PF04857.20 CDJ56038.1 - 0.089 11.9 3.6 0.1 11.8 3.6 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease VIR_N PF15912.5 CDJ56038.1 - 0.099 12.2 3.9 0.13 11.9 3.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Cmyb_C PF09316.10 CDJ56038.1 - 0.1 12.3 7.3 0.14 11.8 7.3 1.3 1 1 0 1 1 1 0 C-myb, C-terminal DUF853 PF05872.12 CDJ56038.1 - 0.16 10.5 10.2 0.2 10.2 10.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAM60A PF15396.6 CDJ56038.1 - 0.2 11.6 4.0 0.21 11.5 4.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4758 PF15950.5 CDJ56038.1 - 0.23 11.8 2.0 0.31 11.4 2.0 1.3 1 1 0 1 1 1 0 Putative sperm flagellar membrane protein DUF4407 PF14362.6 CDJ56038.1 - 0.27 10.5 16.1 0.36 10.1 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dala_Dala_lig_N PF01820.21 CDJ56038.1 - 0.29 11.6 1.2 0.44 11.0 0.8 1.5 2 0 0 2 2 1 0 D-ala D-ala ligase N-terminus AAA_23 PF13476.6 CDJ56038.1 - 0.46 11.0 9.9 0.62 10.5 9.9 1.2 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 CDJ56038.1 - 0.74 9.7 30.1 0.93 9.4 30.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ56038.1 - 1.4 8.0 11.5 1.6 7.7 11.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein THOC2_N PF16134.5 CDJ56038.1 - 1.4 7.5 10.5 1.7 7.2 10.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF5421 PF17458.2 CDJ56038.1 - 1.5 8.2 14.6 2.1 7.7 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF4834 PF16118.5 CDJ56038.1 - 1.6 9.7 8.2 3 8.8 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spore_coat_CotO PF14153.6 CDJ56038.1 - 1.6 8.6 16.5 1.8 8.5 16.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 CDJ56038.1 - 2 7.1 9.9 2.1 7.0 9.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ56038.1 - 2.3 8.2 4.8 2.7 8.0 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ56038.1 - 3.1 6.9 4.1 4.3 6.4 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3292 PF11696.8 CDJ56038.1 - 6.1 5.1 16.9 17 3.6 16.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) AIF_C PF14721.6 CDJ56038.1 - 8 6.8 9.7 9.5 6.6 9.0 1.4 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SNF2_N PF00176.23 CDJ56039.1 - 7.3e-10 38.1 2.5 8e-05 21.5 0.1 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 CDJ56039.1 - 0.044 13.8 0.7 0.28 11.2 0.1 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Spt20 PF12090.8 CDJ56040.1 - 0.00047 19.8 69.7 0.042 13.5 12.8 4.7 5 0 0 5 5 5 4 Spt20 family SNF2_N PF00176.23 CDJ56040.1 - 0.15 10.7 0.0 0.15 10.7 0.0 2.3 3 0 0 3 3 3 0 SNF2 family N-terminal domain DUF2722 PF10846.8 CDJ56040.1 - 0.72 8.7 51.8 0.033 13.1 6.5 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DUF2550 PF10739.9 CDJ56041.1 - 0.085 12.9 0.0 0.37 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Pkinase PF00069.25 CDJ56042.1 - 6.7e-52 176.5 0.0 3.9e-37 128.0 0.0 3.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56042.1 - 1e-23 84.0 0.0 1.8e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ56042.1 - 1.9e-13 48.9 0.7 0.006 16.0 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ56042.1 - 7.7e-13 48.7 0.0 2.6e-05 24.6 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ56042.1 - 3.7e-10 38.9 3.4 0.025 14.5 0.0 4.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDJ56042.1 - 1e-08 34.3 7.3 1.3 8.6 0.4 5.5 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CDJ56042.1 - 7.1e-07 29.0 2.9 1.3 8.9 0.3 5.0 5 0 0 5 5 5 3 EF-hand domain pair Pkinase_fungal PF17667.1 CDJ56042.1 - 0.027 13.2 0.1 1.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CDJ56042.1 - 0.039 13.3 5.4 0.92 8.8 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Bromodomain PF00439.25 CDJ56043.1 - 7.6e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain FYRN PF05964.14 CDJ56043.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus ABC_tran PF00005.27 CDJ56044.1 - 1.9e-35 122.4 50.9 4.8e-19 69.2 1.0 4.7 4 1 0 4 4 3 3 ABC transporter AAA_21 PF13304.6 CDJ56044.1 - 6.9e-28 98.3 0.0 5e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ56044.1 - 1.2e-18 67.4 17.3 1.1e-08 34.8 10.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ56044.1 - 3.5e-09 36.3 0.8 0.0046 16.7 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA PF00004.29 CDJ56044.1 - 5.2e-08 33.4 0.3 0.022 15.2 0.0 4.2 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CDJ56044.1 - 1.1e-07 31.6 0.1 0.016 14.8 0.0 4.1 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CDJ56044.1 - 3.2e-06 26.7 0.6 0.038 13.5 0.1 3.0 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ56044.1 - 6.4e-06 26.2 4.9 0.0085 16.2 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 CDJ56044.1 - 3.3e-05 23.9 2.1 0.17 11.9 0.1 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CDJ56044.1 - 6.8e-05 22.9 2.8 0.091 12.8 0.1 3.9 3 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 CDJ56044.1 - 7.9e-05 22.4 5.5 0.018 14.8 0.4 2.7 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 CDJ56044.1 - 9.9e-05 22.2 1.2 0.54 10.2 0.0 3.4 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 CDJ56044.1 - 0.00011 22.1 3.4 0.00011 22.1 3.4 3.8 3 1 0 4 4 4 2 RsgA GTPase AAA_23 PF13476.6 CDJ56044.1 - 0.00013 22.6 3.3 0.0011 19.5 0.2 7.3 3 3 2 5 5 2 2 AAA domain AAA_22 PF13401.6 CDJ56044.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 5.2 3 2 4 7 7 4 1 AAA domain RNA_helicase PF00910.22 CDJ56044.1 - 0.00017 21.9 0.9 0.22 11.9 0.1 2.9 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CDJ56044.1 - 0.00018 21.1 9.7 0.029 13.9 2.1 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 CDJ56044.1 - 0.00021 21.5 8.2 0.0016 18.7 0.9 5.3 6 0 0 6 6 4 2 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CDJ56044.1 - 0.00023 21.1 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 NTPase T2SSE PF00437.20 CDJ56044.1 - 0.00024 20.2 1.8 0.00024 20.2 1.8 3.6 2 2 0 3 3 3 2 Type II/IV secretion system protein ATPase_2 PF01637.18 CDJ56044.1 - 0.00033 20.7 0.6 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Septin PF00735.18 CDJ56044.1 - 0.00051 19.4 1.6 0.00051 19.4 1.6 4.2 4 1 1 5 5 3 2 Septin SRPRB PF09439.10 CDJ56044.1 - 0.00078 18.9 6.4 0.015 14.7 0.1 3.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 CDJ56044.1 - 0.0014 18.5 0.7 0.0014 18.5 0.7 5.3 2 1 2 4 4 2 1 NACHT domain PRK PF00485.18 CDJ56044.1 - 0.0015 18.3 1.8 0.26 11.0 1.6 2.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 CDJ56044.1 - 0.002 17.7 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Pox_A32 PF04665.12 CDJ56044.1 - 0.0028 17.1 0.5 1.5 8.2 0.0 3.0 4 0 0 4 4 2 1 Poxvirus A32 protein IstB_IS21 PF01695.17 CDJ56044.1 - 0.003 17.3 17.3 0.0062 16.3 0.1 4.6 5 1 0 5 5 3 2 IstB-like ATP binding protein Spt20 PF12090.8 CDJ56044.1 - 0.0044 16.7 11.7 0.0044 16.7 11.7 8.0 5 3 2 7 7 2 1 Spt20 family AAA_25 PF13481.6 CDJ56044.1 - 0.009 15.6 12.2 0.076 12.6 0.0 4.9 4 2 0 4 4 4 2 AAA domain AAA_28 PF13521.6 CDJ56044.1 - 0.01 16.1 0.5 0.01 16.1 0.5 6.9 4 4 2 6 6 3 0 AAA domain AAA_33 PF13671.6 CDJ56044.1 - 0.015 15.5 43.6 0.15 12.2 1.1 5.6 4 3 0 4 4 4 0 AAA domain AAA_13 PF13166.6 CDJ56044.1 - 0.017 13.8 0.1 0.017 13.8 0.1 6.0 5 1 1 6 6 5 0 AAA domain RuvB_N PF05496.12 CDJ56044.1 - 0.023 14.5 0.5 5.4 6.7 0.1 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF4667 PF15700.5 CDJ56044.1 - 0.026 14.6 0.3 0.026 14.6 0.3 4.8 3 2 1 4 4 1 0 Domain of unknown function (DUF4667) Ploopntkinase3 PF18751.1 CDJ56044.1 - 0.031 14.2 8.7 1.3 8.9 0.1 3.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 CDJ56044.1 - 0.032 14.8 12.5 0.098 13.2 0.3 4.5 4 2 0 4 4 3 0 AAA domain GTP_EFTU PF00009.27 CDJ56044.1 - 0.041 13.4 0.0 0.041 13.4 0.0 4.2 3 1 1 4 4 3 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.6 CDJ56044.1 - 0.046 13.4 0.1 0.046 13.4 0.1 4.3 2 2 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 CDJ56044.1 - 0.05 13.3 0.3 0.05 13.3 0.3 5.0 2 2 2 4 4 4 0 AAA domain AAA_5 PF07728.14 CDJ56044.1 - 0.39 10.7 8.1 3.3 7.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 CDJ56044.1 - 1.8 8.3 0.0 1.8 8.3 0.0 3.8 4 1 0 4 4 3 0 Conserved hypothetical ATP binding protein Utp14 PF04615.13 CDJ56044.1 - 6.3 5.2 68.3 0.72 8.4 15.0 3.5 3 1 0 3 3 3 0 Utp14 protein Rad17 PF03215.15 CDJ56044.1 - 6.9 6.6 16.1 0.061 13.2 1.1 3.2 4 0 0 4 4 2 0 Rad17 P-loop domain Gp138_N PF18352.1 CDJ56044.1 - 8.7 6.5 11.2 6.5 6.9 6.8 3.0 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain His_Phos_1 PF00300.22 CDJ56045.1 - 3.5e-06 26.8 26.2 1e-05 25.4 3.6 5.8 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) CENP-L PF13092.6 CDJ56048.1 - 4.2 7.6 7.4 2.6 8.2 3.9 2.2 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 SUIM_assoc PF16619.5 CDJ56048.1 - 7.8 6.6 46.7 0.91 9.6 6.3 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Lactamase_B_2 PF12706.7 CDJ56049.1 - 1e-18 67.6 0.4 5.8e-18 65.1 0.4 2.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDJ56049.1 - 0.00055 19.9 2.5 0.062 13.2 0.0 3.0 2 0 0 2 2 2 2 Beta-lactamase superfamily domain SLC12 PF03522.15 CDJ56050.1 - 0.11 11.4 16.0 0.16 10.9 16.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 EIF4E-T PF10477.9 CDJ56050.1 - 0.23 10.3 26.9 0.28 9.9 26.9 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4407 PF14362.6 CDJ56050.1 - 0.34 10.2 30.0 0.53 9.6 30.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 CDJ56050.1 - 0.42 9.3 12.7 0.55 9.0 12.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 CDJ56050.1 - 1.6 7.9 16.8 64 2.6 19.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Hid1 PF12722.7 CDJ56050.1 - 1.7 6.7 15.3 2.1 6.4 15.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1645 PF07816.11 CDJ56050.1 - 1.9 9.0 12.9 2.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) Zip PF02535.22 CDJ56050.1 - 3.8 6.6 7.8 5.1 6.2 7.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HRDC PF00570.23 CDJ56051.1 - 7.2e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 HRDC domain Maf PF02545.14 CDJ56051.1 - 0.0012 18.7 0.3 0.0019 18.1 0.3 1.4 1 0 0 1 1 1 1 Maf-like protein Slu7 PF11708.8 CDJ56051.1 - 0.15 11.8 18.5 0.24 11.1 18.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Ndc1_Nup PF09531.10 CDJ56051.1 - 1.7 7.3 14.5 2.6 6.6 14.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3492 PF11997.8 CDJ56051.1 - 2.8 7.6 4.8 4.6 6.9 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLN3 PF02487.17 CDJ56051.1 - 5.1 6.0 9.0 9.7 5.1 9.0 1.4 1 0 0 1 1 1 0 CLN3 protein CCSAP PF15748.5 CDJ56051.1 - 5.5 7.1 29.9 0.13 12.4 22.2 1.9 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Gti1_Pac2 PF09729.9 CDJ56051.1 - 6.7 6.8 16.2 6.9 6.7 14.2 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family MAT1 PF06391.13 CDJ56051.1 - 7.5 6.3 26.4 13 5.6 26.4 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Thymidylat_synt PF00303.19 CDJ56052.1 - 3.7e-53 180.4 0.0 5.3e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CDJ56052.1 - 3.6e-09 36.5 0.2 0.00012 21.8 0.0 2.6 2 1 1 3 3 3 2 Dihydrofolate reductase Elong_Iki1 PF10483.9 CDJ56052.1 - 0.0011 18.5 0.7 0.0016 18.0 0.7 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 RskA PF10099.9 CDJ56052.1 - 0.01 16.1 1.1 0.01 16.1 1.1 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ56052.1 - 0.02 14.6 0.2 0.028 14.1 0.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Helicase_C PF00271.31 CDJ56053.1 - 0.00028 21.2 0.0 0.00028 21.2 0.0 5.6 5 2 1 6 6 6 1 Helicase conserved C-terminal domain RskA PF10099.9 CDJ56053.1 - 0.00048 20.5 4.7 0.00048 20.5 4.7 13.3 3 2 8 11 11 11 2 Anti-sigma-K factor rskA Gly_rich PF12810.7 CDJ56054.1 - 0.0021 18.0 0.3 0.0021 18.0 0.3 2.1 2 0 0 2 2 2 1 Glycine rich protein Activator_LAG-3 PF11498.8 CDJ56054.1 - 0.0024 16.9 5.6 0.0024 16.9 5.6 2.9 3 0 0 3 3 3 1 Transcriptional activator LAG-3 LAM_C PF12544.8 CDJ56054.1 - 0.37 11.0 3.6 0.19 11.9 0.2 2.1 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Spt20 PF12090.8 CDJ56054.1 - 0.69 9.5 28.0 0.85 9.2 7.3 3.0 3 0 0 3 3 3 0 Spt20 family DUF3801 PF12687.7 CDJ56054.1 - 6 6.9 18.2 6.5 6.8 16.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Methyltransf_25 PF13649.6 CDJ56055.1 - 8.4e-10 39.2 0.0 1.3e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ56055.1 - 3.3e-09 37.3 0.0 5.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ56055.1 - 1.3e-08 34.8 0.0 5.9e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ56055.1 - 2e-08 34.2 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ56055.1 - 4.7e-06 27.3 0.0 3.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CDJ56055.1 - 4.7e-05 23.2 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 CDJ56055.1 - 0.0039 16.6 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-RING_2 PF13639.6 CDJ56057.1 - 2.6e-07 30.9 5.1 5.2e-07 29.9 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ56057.1 - 1.1e-06 28.8 4.0 3.9e-06 27.1 4.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ56057.1 - 5.7e-06 26.1 1.0 1.3e-05 25.0 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ56057.1 - 1.7e-05 24.6 3.6 3.4e-05 23.6 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ56057.1 - 6e-05 22.7 1.9 0.00014 21.6 1.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger DDHD PF02862.17 CDJ56057.1 - 0.00091 19.5 0.0 0.06 13.5 0.0 2.1 2 0 0 2 2 2 1 DDHD domain EPL1 PF10513.9 CDJ56057.1 - 0.0016 18.9 2.5 0.0062 16.9 0.1 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-ANAPC11 PF12861.7 CDJ56057.1 - 0.0026 17.8 3.6 0.0097 15.9 3.6 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDJ56057.1 - 0.0066 16.4 3.6 0.014 15.3 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Ureide_permease PF07168.11 CDJ56057.1 - 0.051 12.3 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Ureide permease SPX PF03105.19 CDJ56057.1 - 0.075 12.9 15.7 0.12 12.3 1.0 2.0 2 0 0 2 2 2 0 SPX domain Zn_ribbon_17 PF17120.5 CDJ56057.1 - 0.22 11.2 6.6 0.48 10.1 6.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Apt1 PF10351.9 CDJ56057.1 - 0.65 8.8 11.4 0.16 10.8 0.7 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ56057.1 - 2.1 6.3 36.1 0.46 8.5 11.1 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein SOG2 PF10428.9 CDJ56057.1 - 2.9 7.0 17.1 4 6.5 1.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein zf-RING_UBOX PF13445.6 CDJ56057.1 - 5 7.2 11.0 0.13 12.3 3.6 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Bac_rhamnosid PF05592.11 CDJ56059.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain MMR_HSR1 PF01926.23 CDJ56060.1 - 1.6e-14 53.9 0.0 3.3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ56060.1 - 7.4e-06 26.0 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDJ56060.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ56060.1 - 0.014 15.0 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ56060.1 - 0.022 14.8 0.0 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Ham1p_like PF01725.16 CDJ56061.1 - 7.9e-27 94.4 0.0 1.9e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 Ham1 family SR-25 PF10500.9 CDJ56061.1 - 6.7 6.3 15.7 0.46 10.1 10.3 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 CDJ56062.1 - 2.8e-25 89.0 0.6 5.1e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TFIIA PF03153.13 CDJ56062.1 - 2.6e-05 24.4 6.0 2.8e-05 24.3 6.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ56062.1 - 0.0029 16.6 11.1 0.0036 16.3 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PAM2 PF07145.15 CDJ56062.1 - 0.0035 16.9 2.1 0.0071 16.0 0.5 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region MMR_HSR1 PF01926.23 CDJ56062.1 - 0.0048 17.0 0.0 0.036 14.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Med8 PF10232.9 CDJ56062.1 - 0.023 14.3 3.5 0.034 13.7 3.5 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Spt20 PF12090.8 CDJ56062.1 - 0.061 12.9 20.4 0.093 12.3 20.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF2681 PF10883.8 CDJ56062.1 - 0.54 10.7 12.6 1.1 9.7 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Presenilin PF01080.17 CDJ56062.1 - 1.8 7.2 5.9 2.5 6.8 5.9 1.2 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ56062.1 - 3.4 6.0 9.5 4.8 5.5 9.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ribosomal_60s PF00428.19 CDJ56062.1 - 7.7 7.2 16.5 3.1 8.4 12.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LCD1 PF09798.9 CDJ56062.1 - 7.9 4.9 6.9 11 4.5 6.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3438 PF11920.8 CDJ56064.1 - 0.29 10.4 4.2 0.38 10.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF4637 PF15470.6 CDJ56064.1 - 1.5 8.5 6.7 2.3 7.9 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CCSAP PF15748.5 CDJ56065.1 - 1.1 9.4 34.4 0.067 13.4 6.8 3.3 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated PAP1 PF08601.10 CDJ56065.1 - 4.4 6.9 0.0 4.4 6.9 0.0 3.4 2 2 1 3 3 3 0 Transcription factor PAP1 DnaJ PF00226.31 CDJ56066.1 - 1.3e-11 44.4 0.1 3.3e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 CDJ56067.1 - 5e-52 173.6 0.3 5e-16 58.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CDJ56067.1 - 9.2e-11 41.6 2.1 2.1e-10 40.5 2.1 1.6 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 CDJ56067.1 - 1.6e-08 34.6 0.0 0.014 15.5 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CDJ56067.1 - 5.4e-08 32.5 0.1 0.002 17.7 0.0 3.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDJ56067.1 - 8.4e-06 25.7 0.0 0.099 12.7 0.0 3.6 3 0 0 3 3 3 2 RNA binding domain Zip PF02535.22 CDJ56067.1 - 0.083 12.1 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 CDJ56067.1 - 0.25 9.9 10.3 0.4 9.2 10.3 1.4 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ56067.1 - 0.43 9.4 11.0 0.6 8.9 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ56067.1 - 1.2 7.7 12.1 2.2 6.9 12.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ56067.1 - 1.7 7.4 8.1 2.4 6.8 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hamartin PF04388.12 CDJ56067.1 - 5.8 5.5 13.5 1.2 7.7 9.8 1.7 2 0 0 2 2 2 0 Hamartin protein PAT1 PF09770.9 CDJ56070.1 - 4.6 5.4 27.9 6.2 5.0 27.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hexokinase_1 PF00349.21 CDJ56071.1 - 2e-52 178.0 0.0 2.8e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CDJ56071.1 - 3.4e-22 79.0 3.1 1.7e-16 60.4 0.1 2.5 2 1 0 2 2 2 2 Hexokinase VanY PF02557.17 CDJ56071.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase FGGY_N PF00370.21 CDJ56071.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF2009 PF09418.10 CDJ56072.1 - 1.4e-30 106.8 2.9 5.9e-18 65.2 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) T6SS_VipA PF05591.12 CDJ56072.1 - 0.0098 15.7 0.1 0.03 14.1 0.1 1.7 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Btz PF09405.10 CDJ56073.1 - 4.1e-11 43.3 9.2 4.1e-11 43.3 9.2 2.3 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding EphA2_TM PF14575.6 CDJ56074.1 - 0.048 14.6 0.2 0.42 11.5 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RRM_1 PF00076.22 CDJ56075.1 - 6.6e-17 61.1 0.0 4.1e-08 32.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitoc_mL59 PF18126.1 CDJ56077.1 - 7.2e-05 23.1 3.3 0.0014 19.0 3.3 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Ank_2 PF12796.7 CDJ56078.1 - 5.7e-21 74.9 0.1 2e-16 60.3 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ56078.1 - 2.3e-20 72.7 0.5 1.9e-12 47.4 0.0 4.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ56078.1 - 1.1e-18 65.4 2.7 4e-07 29.8 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CDJ56078.1 - 2.5e-16 59.3 5.6 1.2e-06 28.7 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CDJ56078.1 - 3.3e-13 49.5 1.4 5e-10 39.4 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) SET PF00856.28 CDJ56078.1 - 0.00012 22.6 0.0 0.0007 20.0 0.0 2.4 3 1 0 3 3 3 1 SET domain AAA PF00004.29 CDJ56080.1 - 2.7e-41 141.1 0.0 7e-41 139.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ56080.1 - 8.8e-12 44.6 0.1 2e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDJ56080.1 - 2.6e-11 43.3 0.5 7.4e-11 41.8 0.5 1.9 1 1 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CDJ56080.1 - 1.3e-06 28.5 0.1 6.9e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ56080.1 - 4.3e-05 24.0 0.6 0.0044 17.4 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 CDJ56080.1 - 8.1e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ56080.1 - 0.00036 20.7 0.0 0.0017 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ56080.1 - 0.00071 19.9 0.7 0.08 13.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ56080.1 - 0.0031 17.7 0.1 0.01 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ56080.1 - 0.0037 16.7 0.3 0.014 14.8 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CDJ56080.1 - 0.0064 15.9 0.2 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 CDJ56080.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 CDJ56080.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDJ56080.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CDJ56080.1 - 0.039 13.7 0.1 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDJ56080.1 - 0.071 12.3 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain CENP-F_leu_zip PF10473.9 CDJ56080.1 - 0.075 13.1 2.2 0.33 11.0 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sigma54_activat PF00158.26 CDJ56080.1 - 0.078 12.7 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ZapB PF06005.12 CDJ56080.1 - 0.1 13.1 3.6 0.2 12.1 1.7 2.4 2 0 0 2 2 2 0 Cell division protein ZapB AAA_7 PF12775.7 CDJ56080.1 - 0.11 12.1 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Exo_endo_phos PF03372.23 CDJ56081.1 - 1.5e-11 44.3 0.5 9.8e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-primase PF09329.11 CDJ56082.1 - 5.9e-08 32.4 0.9 1.6e-07 31.0 0.9 1.8 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 CDJ56082.1 - 0.0045 16.5 15.5 0.0045 16.5 15.5 4.1 3 1 0 3 3 3 1 Mcm10 replication factor T2SSF PF00482.23 CDJ56082.1 - 0.11 12.5 1.3 1.4 8.9 0.3 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Ndc80_HEC PF03801.13 CDJ56083.1 - 0.00084 19.0 0.1 0.00097 18.8 0.1 1.1 1 0 0 1 1 1 1 HEC/Ndc80p family Ufd2P_core PF10408.9 CDJ56084.1 - 1.1e-69 235.8 0.0 3.5e-38 131.6 0.0 3.0 1 1 1 2 2 2 2 Ubiquitin elongating factor core Nuf2 PF03800.14 CDJ56086.1 - 0.014 15.6 0.2 0.014 15.6 0.2 1.8 2 0 0 2 2 2 0 Nuf2 family SR-25 PF10500.9 CDJ56086.1 - 1.3 8.6 16.1 0.43 10.2 12.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein eRF1_1 PF03463.15 CDJ56089.1 - 7.3e-27 93.9 0.0 2.7e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 CDJ56089.1 - 9e-17 61.6 0.0 3.2e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 eRF1 domain 3 MID_MedPIWI PF18296.1 CDJ56089.1 - 0.0018 18.1 1.4 0.0029 17.4 1.4 1.2 1 0 0 1 1 1 1 MID domain of medPIWI Spt20 PF12090.8 CDJ56089.1 - 0.0082 15.8 7.0 0.012 15.3 5.0 2.0 2 0 0 2 2 2 1 Spt20 family DUF1645 PF07816.11 CDJ56089.1 - 0.017 15.7 4.7 0.24 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4667 PF15700.5 CDJ56089.1 - 0.11 12.5 6.4 0.099 12.7 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) DUF4834 PF16118.5 CDJ56089.1 - 0.12 13.3 5.7 0.93 10.5 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1644 PF07800.12 CDJ56089.1 - 0.43 10.6 5.0 0.7 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) Herpes_pp85 PF04637.12 CDJ56089.1 - 1.2 7.5 2.8 2.2 6.6 2.8 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) U1snRNP70_N PF12220.8 CDJ56089.1 - 1.4 9.6 6.1 0.22 12.2 0.9 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal IMUP PF15761.5 CDJ56089.1 - 2.3 9.0 9.5 9.6 7.0 9.5 2.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ56089.1 - 3.3 7.3 17.7 0.073 12.7 9.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tfb4 PF03850.14 CDJ56090.1 - 6.1e-08 32.5 3.1 1.3e-07 31.5 1.2 2.0 1 1 1 2 2 2 1 Transcription factor Tfb4 RskA PF10099.9 CDJ56090.1 - 1e-06 29.2 5.8 1e-06 29.2 5.8 2.4 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ56090.1 - 0.00012 21.2 2.1 0.00016 20.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ56090.1 - 0.001 19.2 17.6 0.0013 18.9 17.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ56090.1 - 0.0068 16.0 15.9 0.013 15.1 15.9 1.3 1 0 0 1 1 1 1 Spt20 family FAS_N PF17828.1 CDJ56090.1 - 0.012 15.6 0.2 0.02 14.9 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta T6SS_TssF PF05947.12 CDJ56090.1 - 0.013 14.0 0.7 0.019 13.5 0.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF P5-ATPase PF12409.8 CDJ56090.1 - 0.061 13.4 0.3 0.097 12.8 0.3 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter FixO PF02433.15 CDJ56090.1 - 0.083 12.3 1.1 0.12 11.8 1.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4834 PF16118.5 CDJ56090.1 - 0.18 12.8 1.7 0.31 12.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SPX PF03105.19 CDJ56090.1 - 0.77 9.6 6.1 1.2 9.0 6.1 1.2 1 0 0 1 1 1 0 SPX domain DUF2489 PF10675.9 CDJ56090.1 - 1 9.3 10.3 1.5 8.7 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DivIC PF04977.15 CDJ56090.1 - 1 9.1 10.8 1.2 8.9 9.3 1.7 2 0 0 2 2 2 0 Septum formation initiator Spt20 PF12090.8 CDJ56091.1 - 0.0016 18.1 11.4 0.0016 18.1 11.4 7.0 3 2 1 4 4 4 1 Spt20 family BBS1 PF14779.6 CDJ56092.1 - 3.3 7.1 6.3 6.4 6.1 6.3 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Tam41_Mmp37 PF09139.11 CDJ56092.1 - 4.3 6.7 7.3 5.2 6.4 4.2 2.3 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial TIP49 PF06068.13 CDJ56093.1 - 1.8e-158 527.4 0.0 2.1e-158 527.1 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 CDJ56093.1 - 3.1e-11 43.8 0.2 7.3e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ56093.1 - 2.1e-08 34.1 0.4 5.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ56093.1 - 5.3e-07 30.2 2.9 7.7e-06 26.4 2.9 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ56093.1 - 6.3e-06 26.2 0.1 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ56093.1 - 8.4e-06 26.1 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 CDJ56093.1 - 1.2e-05 24.8 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 CDJ56093.1 - 3.1e-05 24.3 0.1 3.1e-05 24.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 CDJ56093.1 - 5.4e-05 22.6 0.1 0.00017 20.9 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 CDJ56093.1 - 7.2e-05 22.5 0.0 0.083 12.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDJ56093.1 - 8.4e-05 22.0 0.5 0.0082 15.5 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CDJ56093.1 - 0.00031 21.2 0.2 0.0007 20.0 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 CDJ56093.1 - 0.00085 18.9 0.0 0.00085 18.9 0.0 2.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CDJ56093.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CDJ56093.1 - 0.0042 17.2 0.1 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ56093.1 - 0.0042 17.6 0.0 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDJ56093.1 - 0.0074 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDJ56093.1 - 0.0083 15.7 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 CDJ56093.1 - 0.012 15.0 0.9 0.019 14.3 0.1 1.7 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 CDJ56093.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 CDJ56093.1 - 0.025 14.8 0.6 0.1 12.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CDJ56093.1 - 0.027 14.5 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDJ56093.1 - 0.035 13.8 0.2 0.065 13.0 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CDJ56093.1 - 0.038 14.0 0.8 0.086 12.9 0.2 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 CDJ56093.1 - 0.043 13.7 4.0 0.11 12.3 0.0 2.8 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 CDJ56093.1 - 0.057 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 CDJ56093.1 - 0.058 13.4 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ56093.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CDJ56093.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Ribosomal_60s PF00428.19 CDJ56093.1 - 4.8 7.8 20.1 34 5.1 17.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2722 PF10846.8 CDJ56094.1 - 0.00017 20.7 4.3 0.00017 20.7 4.3 12.2 10 2 2 12 12 12 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ56094.1 - 0.00075 19.2 9.7 0.00075 19.2 9.7 11.3 9 3 2 11 11 11 4 Spt20 family PNISR PF15996.5 CDJ56094.1 - 0.0013 19.0 6.3 0.0013 19.0 6.3 8.8 10 0 0 10 10 10 2 Arginine/serine-rich protein PNISR Cnd1 PF12717.7 CDJ56094.1 - 0.0026 17.8 3.9 12 6.0 0.0 5.5 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 SARAF PF06682.12 CDJ56094.1 - 0.009 15.7 0.1 0.009 15.7 0.1 8.4 7 2 0 7 7 7 1 SOCE-associated regulatory factor of calcium homoeostasis HEAT PF02985.22 CDJ56094.1 - 0.86 10.0 16.7 5 7.6 0.1 6.9 7 0 0 7 7 7 0 HEAT repeat Myb_DNA-binding PF00249.31 CDJ56095.1 - 0.00031 20.9 1.5 0.00065 19.8 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2722 PF10846.8 CDJ56095.1 - 0.0022 17.0 11.5 0.0022 17.0 11.5 10.0 8 3 1 9 9 9 1 Protein of unknown function (DUF2722) NAC PF01849.18 CDJ56096.1 - 5.3e-19 67.9 0.0 9.4e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 NAC domain MRI PF15325.6 CDJ56096.1 - 3 9.0 10.6 0.63 11.1 6.6 1.9 2 0 0 2 2 2 0 Modulator of retrovirus infection PGK PF00162.19 CDJ56097.1 - 1.7e-144 481.4 2.8 4.1e-143 476.9 2.8 2.0 1 1 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S51 PF03575.17 CDJ56097.1 - 0.071 12.7 0.3 3.3 7.3 0.1 2.9 3 0 0 3 3 3 0 Peptidase family S51 GT87 PF09594.10 CDJ56098.1 - 0.045 13.5 4.3 0.082 12.6 4.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 B-block_TFIIIC PF04182.12 CDJ56099.1 - 2.2e-08 34.1 0.0 2e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC adh_short PF00106.25 CDJ56100.1 - 3.4e-20 72.3 0.0 1.6e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ56100.1 - 1.6e-12 47.5 0.0 3.2e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ56100.1 - 9.9e-07 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain polyprenyl_synt PF00348.17 CDJ56103.1 - 5.1e-58 196.1 0.0 1.2e-56 191.6 0.0 2.6 1 1 0 1 1 1 1 Polyprenyl synthetase SHS2_Rpb7-N PF03876.17 CDJ56104.1 - 6.3e-13 48.9 0.1 1e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDJ56104.1 - 1.8e-07 31.4 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 CDJ56104.1 - 0.055 13.7 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DRY_EERY PF09750.9 CDJ56105.1 - 8.8e-08 32.5 0.5 8.8e-08 32.5 0.5 4.2 3 1 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 CDJ56105.1 - 3.5e-07 30.1 5.7 5.1e-07 29.6 0.1 3.1 3 0 0 3 3 3 1 Surp module SET PF00856.28 CDJ56105.1 - 0.65 10.4 8.5 3 8.2 0.5 3.1 2 1 0 2 2 2 0 SET domain DUF3837 PF12939.7 CDJ56105.1 - 1.5 9.3 3.8 1.9 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) SCIMP PF15050.6 CDJ56105.1 - 7.5 7.0 9.6 1.5 9.2 0.2 3.5 3 0 0 3 3 3 0 SCIMP protein LRR_4 PF12799.7 CDJ56106.1 - 3.4e-19 68.6 22.1 2.6e-06 27.7 0.0 5.7 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ56106.1 - 8e-17 60.8 22.6 2e-08 33.9 2.0 4.8 1 1 6 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 CDJ56106.1 - 3.4e-14 52.7 0.4 8.8e-07 28.6 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDJ56106.1 - 0.00014 22.0 16.2 2.3 9.1 0.0 7.4 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ56106.1 - 0.00016 21.5 15.0 3 8.1 0.0 6.3 5 1 0 5 5 5 3 Leucine Rich repeat DUF4381 PF14316.6 CDJ56107.1 - 0.01 16.1 0.4 0.016 15.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DprA_WH PF17782.1 CDJ56108.1 - 0.085 13.0 2.5 0.13 12.3 0.5 2.4 2 0 0 2 2 2 0 DprA winged helix domain FtsJ PF01728.19 CDJ56110.1 - 3.2e-33 115.3 0.0 5.6e-28 98.2 0.0 3.8 1 1 1 2 2 2 2 FtsJ-like methyltransferase RskA PF10099.9 CDJ56110.1 - 1.3e-07 32.1 3.1 1.3e-07 32.1 3.1 4.0 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ56110.1 - 0.006 15.7 8.9 0.006 15.7 8.9 1.8 2 0 0 2 2 2 1 Drosophila roughex protein Herpes_UL74 PF07982.12 CDJ56110.1 - 0.82 8.6 4.3 1.5 7.7 4.3 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins PAS PF00989.25 CDJ56110.1 - 2.2 8.3 4.5 4.1 7.4 4.5 1.4 1 0 0 1 1 1 0 PAS fold THRAP3_BCLAF1 PF15440.6 CDJ56110.1 - 7.2 5.5 35.2 11 4.9 35.2 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Otopetrin PF03189.13 CDJ56110.1 - 9.6 4.9 8.0 0.33 9.7 1.0 1.9 2 0 0 2 2 2 0 Otopetrin TFIIA PF03153.13 CDJ56111.1 - 0.00039 20.6 34.5 0.0005 20.2 34.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ56111.1 - 0.0023 16.3 20.7 0.0023 16.3 20.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 UPF0564 PF10595.9 CDJ56111.1 - 0.0052 15.9 16.1 0.0064 15.6 16.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 DUF1980 PF09323.10 CDJ56111.1 - 0.0054 16.7 8.2 0.0083 16.1 8.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) DDHD PF02862.17 CDJ56111.1 - 0.0076 16.4 6.0 0.0082 16.3 6.0 1.2 1 0 0 1 1 1 1 DDHD domain DUF4471 PF14740.6 CDJ56111.1 - 0.0084 15.4 1.8 0.0098 15.1 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) SOG2 PF10428.9 CDJ56111.1 - 0.0096 15.2 15.8 0.011 15.0 15.8 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein EPL1 PF10513.9 CDJ56111.1 - 0.012 16.0 7.4 0.014 15.8 7.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Miga PF10265.9 CDJ56111.1 - 0.013 14.5 7.8 0.015 14.3 7.8 1.0 1 0 0 1 1 1 0 Mitoguardin SWI-SNF_Ssr4 PF08549.10 CDJ56111.1 - 0.023 13.4 17.3 0.025 13.2 17.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SpoIIP PF07454.11 CDJ56111.1 - 0.026 14.0 8.6 0.029 13.8 8.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PhetRS_B1 PF18262.1 CDJ56111.1 - 0.026 14.7 1.5 0.065 13.5 1.5 1.7 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain DUF4746 PF15928.5 CDJ56111.1 - 0.03 13.8 3.9 0.036 13.5 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5134 PF17197.4 CDJ56111.1 - 0.032 14.1 9.3 0.055 13.4 6.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) DUF4638 PF15472.6 CDJ56111.1 - 0.052 13.3 5.3 0.055 13.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) MMR1 PF08505.10 CDJ56111.1 - 0.081 13.2 12.7 0.1 12.9 12.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FRQ PF09421.10 CDJ56111.1 - 0.087 10.8 9.4 0.1 10.6 9.4 1.0 1 0 0 1 1 1 0 Frequency clock protein SLC12 PF03522.15 CDJ56111.1 - 0.11 11.5 10.5 0.13 11.3 10.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 CDJ56111.1 - 0.11 11.3 8.2 0.13 11.1 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DDOST_48kD PF03345.14 CDJ56111.1 - 0.12 11.2 8.8 0.16 10.8 8.8 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta TERB2 PF15101.6 CDJ56111.1 - 0.14 12.2 16.4 0.2 11.7 16.4 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 CDJ56111.1 - 0.2 10.4 14.6 0.22 10.2 14.6 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ56111.1 - 0.21 10.5 15.0 0.26 10.2 15.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sin_N PF04801.13 CDJ56111.1 - 0.26 10.5 22.1 0.33 10.1 22.1 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Med15 PF09606.10 CDJ56111.1 - 0.27 9.9 40.3 0.34 9.5 40.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HGTP_anticodon2 PF12745.7 CDJ56111.1 - 0.28 10.7 12.2 0.4 10.2 12.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Spore_III_AF PF09581.10 CDJ56111.1 - 0.3 11.1 14.0 0.54 10.3 14.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ndc1_Nup PF09531.10 CDJ56111.1 - 0.37 9.4 14.2 0.42 9.3 14.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 CDJ56111.1 - 0.44 8.4 11.7 0.53 8.1 11.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 CDJ56111.1 - 0.45 8.9 4.2 0.51 8.7 4.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_transf_41 PF13844.6 CDJ56111.1 - 0.45 8.9 6.3 0.54 8.6 6.3 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 EIIBC-GUT_N PF03612.14 CDJ56111.1 - 0.47 10.2 9.3 0.77 9.5 9.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NST1 PF13945.6 CDJ56111.1 - 0.48 10.5 20.2 0.66 10.1 20.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator CLN3 PF02487.17 CDJ56111.1 - 0.49 9.4 8.1 0.65 9.0 8.1 1.2 1 0 0 1 1 1 0 CLN3 protein Macoilin PF09726.9 CDJ56111.1 - 0.57 8.7 15.0 0.76 8.3 15.0 1.2 1 0 0 1 1 1 0 Macoilin family CSG2 PF16965.5 CDJ56111.1 - 0.61 9.0 5.0 0.73 8.7 5.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 CDJ56111.1 - 0.81 9.5 11.6 1.1 9.1 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIT1 PF01988.19 CDJ56111.1 - 0.82 9.5 12.1 1.2 8.9 12.1 1.3 1 0 0 1 1 1 0 VIT family Membralin PF09746.9 CDJ56111.1 - 0.82 8.6 7.2 0.96 8.4 7.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 CDJ56111.1 - 0.84 8.0 11.5 0.99 7.8 11.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 FemAB PF02388.16 CDJ56111.1 - 0.93 8.3 14.4 1.2 7.9 14.4 1.1 1 0 0 1 1 1 0 FemAB family GREB1 PF15782.5 CDJ56111.1 - 1 6.4 17.5 1.1 6.2 17.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WTX PF09422.10 CDJ56111.1 - 1.1 8.3 10.5 1.3 8.0 10.5 1.1 1 0 0 1 1 1 0 WTX protein Lin-8 PF03353.15 CDJ56111.1 - 1.2 8.6 20.5 1.5 8.3 20.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TALPID3 PF15324.6 CDJ56111.1 - 1.5 6.4 25.0 2.3 5.8 25.0 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Scs3p PF10261.9 CDJ56111.1 - 1.5 8.2 4.2 2.1 7.8 4.2 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Band_3_cyto PF07565.13 CDJ56111.1 - 1.5 8.5 11.9 2.2 8.0 11.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Arb1 PF09692.10 CDJ56111.1 - 1.6 7.8 10.4 1.9 7.6 10.4 1.1 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Neur_chan_memb PF02932.16 CDJ56111.1 - 1.6 8.7 9.6 1.9 8.5 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4449 PF14613.6 CDJ56111.1 - 1.6 8.8 15.6 2.5 8.2 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF1387 PF07139.11 CDJ56111.1 - 1.6 8.4 14.4 2 8.1 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Paramyxo_ncap PF00973.19 CDJ56111.1 - 1.7 7.4 8.4 2 7.2 8.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein EOS1 PF12326.8 CDJ56111.1 - 1.8 8.5 5.0 2.7 7.9 5.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein FAM60A PF15396.6 CDJ56111.1 - 2.1 8.3 7.0 2.7 8.0 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ctr PF04145.15 CDJ56111.1 - 2.2 8.9 5.5 3 8.5 5.5 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF2828 PF11443.8 CDJ56111.1 - 2.3 6.2 13.1 2.9 5.9 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIF4E-T PF10477.9 CDJ56111.1 - 2.4 6.9 22.9 2.9 6.6 22.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2126 PF09899.9 CDJ56111.1 - 3.2 5.7 10.3 3.9 5.4 10.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Sec62 PF03839.16 CDJ56111.1 - 3.2 7.2 9.5 4.2 6.8 9.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 HCO3_cotransp PF00955.21 CDJ56111.1 - 3.2 6.5 4.6 4.1 6.1 4.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family LMBR1 PF04791.16 CDJ56111.1 - 3.3 6.5 4.8 3.6 6.4 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Activator_LAG-3 PF11498.8 CDJ56111.1 - 3.7 6.4 51.1 5 6.0 51.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ALMT PF11744.8 CDJ56111.1 - 4.1 6.1 11.1 5 5.8 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 CDJ56111.1 - 4.3 7.4 10.8 5.9 6.9 10.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family YABBY PF04690.13 CDJ56111.1 - 4.7 7.7 10.9 7 7.2 10.9 1.3 1 0 0 1 1 1 0 YABBY protein OATP PF03137.20 CDJ56111.1 - 5.8 5.1 5.3 6.8 4.8 5.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hid1 PF12722.7 CDJ56111.1 - 5.8 4.9 14.1 7 4.6 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.16 CDJ56111.1 - 6.2 6.6 9.7 7.9 6.3 9.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Apc15p PF05841.11 CDJ56111.1 - 6.3 7.6 23.0 8 7.3 22.3 1.6 1 1 0 1 1 1 0 Apc15p protein R3H-assoc PF13902.6 CDJ56111.1 - 6.3 7.2 16.7 15 6.0 16.7 1.6 1 1 0 1 1 1 0 R3H-associated N-terminal domain Tim54 PF11711.8 CDJ56111.1 - 8.1 5.1 13.3 10 4.8 13.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RskA PF10099.9 CDJ56111.1 - 9.3 6.5 56.0 8.2 6.7 29.5 3.3 1 1 1 2 2 1 0 Anti-sigma-K factor rskA PIP5K PF01504.18 CDJ56111.1 - 9.5 5.3 11.0 12 5.0 11.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PepSY_TM_like_2 PF16357.5 CDJ56111.1 - 9.8 6.1 8.5 13 5.7 8.5 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like Pkinase PF00069.25 CDJ56112.1 - 3.9e-22 78.9 0.0 3.7e-14 52.7 0.6 3.7 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56112.1 - 3e-10 39.8 11.0 3.4e-06 26.5 0.0 3.0 4 0 0 4 4 4 2 Protein tyrosine kinase PH_15 PF17339.2 CDJ56112.1 - 0.00065 19.6 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 PH domain SDA1 PF05285.12 CDJ56112.1 - 0.0035 16.8 5.6 0.0035 16.8 5.6 4.9 4 1 0 4 4 4 2 SDA1 DUF2722 PF10846.8 CDJ56112.1 - 0.0091 15.0 0.5 0.0091 15.0 0.5 7.2 5 3 1 6 6 6 1 Protein of unknown function (DUF2722) Utp14 PF04615.13 CDJ56112.1 - 0.039 12.6 64.1 0.0076 14.9 34.9 3.2 3 0 0 3 3 3 0 Utp14 protein TMEM51 PF15345.6 CDJ56113.1 - 0.0031 17.4 10.1 0.0031 17.4 10.1 2.8 3 0 0 3 3 3 1 Transmembrane protein 51 AAA_23 PF13476.6 CDJ56113.1 - 1.1 9.7 15.8 0.054 14.0 8.4 2.1 2 0 0 2 2 2 0 AAA domain DNA_pol3_a_NII PF11490.8 CDJ56113.1 - 7.1 6.5 25.7 63 3.5 0.1 3.3 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II Neur_chan_memb PF02932.16 CDJ56113.1 - 7.4 6.6 14.1 2 8.4 7.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RskA PF10099.9 CDJ56114.1 - 0.0029 17.9 0.1 0.0029 17.9 0.1 4.3 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF5349 PF17298.2 CDJ56115.1 - 0.95 9.2 23.0 1.3 8.8 23.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Secretin_N_2 PF07655.13 CDJ56115.1 - 4.6 7.9 20.1 8.1 7.1 5.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain RHD3 PF05879.12 CDJ56116.1 - 1.6e-47 162.2 0.7 4e-47 160.9 0.7 1.6 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) SR-25 PF10500.9 CDJ56116.1 - 0.0014 18.3 1.2 0.0026 17.4 1.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Osw5 PF17062.5 CDJ56116.1 - 0.0069 16.5 1.1 0.0069 16.5 1.1 2.4 2 0 0 2 2 2 1 Outer spore wall 5 DUF2207 PF09972.9 CDJ56116.1 - 0.013 14.3 5.1 0.51 9.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Wzy_C PF04932.15 CDJ56116.1 - 0.037 13.7 3.2 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 O-Antigen ligase QueT PF06177.11 CDJ56116.1 - 0.2 12.0 14.3 0.41 11.0 14.3 1.5 1 0 0 1 1 1 0 QueT transporter FA_desaturase PF00487.24 CDJ56116.1 - 0.75 9.6 6.7 6.9 6.4 0.6 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Mit_KHE1 PF10173.9 CDJ56117.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related ANAPC2 PF08672.11 CDJ56118.1 - 0.0009 19.7 0.1 0.005 17.3 0.1 2.3 1 1 1 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Sec34 PF04136.15 CDJ56118.1 - 0.0065 16.4 1.2 1.1 9.1 0.1 2.3 2 0 0 2 2 2 2 Sec34-like family SHE3 PF17078.5 CDJ56118.1 - 0.011 15.5 7.0 0.016 14.9 7.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BCAS2 PF05700.11 CDJ56118.1 - 0.18 11.5 3.9 0.8 9.4 3.9 1.9 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Wbp11 PF09429.10 CDJ56118.1 - 3.1 8.3 7.3 6.2 7.3 0.5 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 MCU PF04678.13 CDJ56118.1 - 9.4 6.3 6.8 43 4.1 6.4 2.2 2 1 0 2 2 2 0 Mitochondrial calcium uniporter LYTB PF02401.18 CDJ56119.1 - 6.2e-84 281.4 0.9 7.9e-84 281.0 0.9 1.1 1 0 0 1 1 1 1 LytB protein Ank_2 PF12796.7 CDJ56121.1 - 2e-22 79.5 0.0 1.5e-11 44.7 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ56121.1 - 6.4e-14 51.8 0.1 1.1e-05 25.6 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ56121.1 - 1.4e-11 44.7 0.0 4.6e-09 36.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ56121.1 - 5.9e-11 41.6 0.0 0.0011 19.3 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ56121.1 - 8.1e-09 35.5 0.0 5.3e-05 23.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Myosin_head PF00063.21 CDJ56122.1 - 9.7e-185 615.6 0.2 1.2e-184 615.3 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ56122.1 - 0.016 15.6 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ56122.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ56122.1 - 0.051 13.8 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 CDJ56122.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 CDJ56122.1 - 0.12 12.8 0.0 0.52 10.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 CDJ56123.1 - 2.5e-66 223.0 0.1 3.8e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDJ56123.1 - 5.9e-31 106.8 0.0 4.8e-30 103.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDJ56123.1 - 4.1e-19 68.4 0.0 9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDJ56123.1 - 8.9e-15 54.6 0.0 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ56123.1 - 9.3e-12 45.2 0.1 2.2e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ56123.1 - 5.5e-05 23.2 0.1 0.00012 22.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CDJ56123.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Shikimate_DH PF01488.20 CDJ56123.1 - 0.027 14.5 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SRPRB PF09439.10 CDJ56123.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-AN1 PF01428.16 CDJ56124.1 - 2.4e-20 72.4 22.6 5.5e-13 48.8 7.8 2.5 2 1 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 CDJ56124.1 - 0.00014 22.2 11.9 0.0085 16.5 4.3 2.5 2 1 0 2 2 2 2 C5HC2 zinc finger Transp_Tc5_C PF04236.15 CDJ56124.1 - 0.007 16.7 14.4 0.19 12.1 3.4 2.4 2 1 0 2 2 2 2 Tc5 transposase C-terminal domain Zn-ribbon_8 PF09723.10 CDJ56124.1 - 0.037 14.2 8.4 0.24 11.6 1.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain IBR PF01485.21 CDJ56124.1 - 0.18 12.0 16.2 2.9 8.2 4.7 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CDJ56124.1 - 0.52 10.5 12.7 0.18 11.9 6.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_4 PF13717.6 CDJ56124.1 - 0.69 9.9 7.8 4.9 7.2 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain SBP PF03110.14 CDJ56124.1 - 1.2 9.5 10.8 1.9 8.9 3.3 2.4 1 1 1 2 2 2 0 SBP domain zf_UBZ PF18439.1 CDJ56124.1 - 2 8.0 7.9 16 5.2 0.9 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 CDJ56124.1 - 3.4 7.4 9.2 0.77 9.5 3.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.6 CDJ56124.1 - 8.8 6.4 11.8 7.9 6.6 2.1 2.6 2 1 1 3 3 3 0 CpXC protein GREB1 PF15782.5 CDJ56126.1 - 7 3.6 33.8 8.4 3.4 33.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 CDJ56127.1 - 3.6e-50 170.8 0.1 3.9e-36 124.8 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56127.1 - 1.5e-18 67.0 0.0 5e-09 35.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Spt20 PF12090.8 CDJ56127.1 - 5.3e-05 22.9 31.1 0.00037 20.2 2.4 2.2 2 0 0 2 2 2 2 Spt20 family BAT2_N PF07001.11 CDJ56127.1 - 0.00091 19.7 3.2 0.00091 19.7 3.2 2.3 2 0 0 2 2 2 1 BAT2 N-terminus Kinase-like PF14531.6 CDJ56127.1 - 0.012 15.0 0.0 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CDJ56127.1 - 0.036 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gti1_Pac2 PF09729.9 CDJ56127.1 - 0.63 10.1 8.7 11 6.1 6.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family PNISR PF15996.5 CDJ56127.1 - 2.5 8.3 13.4 15 5.8 7.9 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR BAF1_ABF1 PF04684.13 CDJ56127.1 - 3.7 6.5 13.5 40 3.1 13.8 1.9 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 CDJ56127.1 - 3.9 7.0 19.0 4.4 6.8 8.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MACPF PF01823.19 CDJ56127.1 - 5.5 7.0 16.2 0.53 10.3 6.2 2.3 2 0 0 2 2 2 0 MAC/Perforin domain Ribosomal_60s PF00428.19 CDJ56127.1 - 7.5 7.2 7.9 30 5.3 1.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein LcrV PF04792.12 CDJ56128.1 - 0.0058 16.0 0.0 0.0078 15.5 0.0 1.1 1 0 0 1 1 1 1 V antigen (LcrV) protein SET PF00856.28 CDJ56128.1 - 0.02 15.3 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 SET domain DUF1682 PF07946.14 CDJ56128.1 - 0.022 14.0 2.1 0.029 13.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5523 PF17661.1 CDJ56128.1 - 0.034 13.8 7.6 0.047 13.4 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Pes-10 PF07149.11 CDJ56128.1 - 0.064 12.3 8.7 0.089 11.8 8.7 1.1 1 0 0 1 1 1 0 Pes-10 Paf1 PF03985.13 CDJ56128.1 - 0.35 9.8 11.3 0.44 9.5 11.3 1.1 1 0 0 1 1 1 0 Paf1 zf-B_box PF00643.24 CDJ56129.1 - 9.3e-10 38.5 16.4 4.3e-05 23.6 2.5 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 CDJ56129.1 - 0.035 14.3 9.8 0.11 12.7 0.7 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RskA PF10099.9 CDJ56130.1 - 0.0019 18.5 0.0 0.012 15.9 0.0 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA DUF3446 PF11928.8 CDJ56130.1 - 0.02 15.2 9.8 0.02 15.2 9.8 2.6 3 0 0 3 3 3 0 Early growth response N-terminal domain Chorion_2 PF03964.15 CDJ56130.1 - 0.03 15.2 2.7 0.03 15.2 2.7 2.8 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_L27A PF00828.19 CDJ56132.1 - 3.4e-20 73.0 0.0 4.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A BAF1_ABF1 PF04684.13 CDJ56133.1 - 0.00046 19.4 10.8 0.00071 18.8 10.8 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SUIM_assoc PF16619.5 CDJ56133.1 - 0.00052 20.0 0.0 0.00052 20.0 0.0 4.4 2 2 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 CDJ56133.1 - 0.026 12.9 1.1 0.039 12.4 1.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MID_MedPIWI PF18296.1 CDJ56133.1 - 0.035 13.9 8.1 0.11 12.3 7.2 2.0 2 0 0 2 2 2 0 MID domain of medPIWI Spt20 PF12090.8 CDJ56133.1 - 0.066 12.8 48.7 0.41 10.2 4.3 2.3 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ56133.1 - 0.25 10.9 16.7 0.014 15.0 11.2 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.10 CDJ56133.1 - 0.57 10.0 11.2 0.29 10.9 8.4 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NOA36 PF06524.12 CDJ56133.1 - 0.62 9.3 16.2 0.92 8.8 16.2 1.3 1 0 0 1 1 1 0 NOA36 protein CCDC53 PF10152.9 CDJ56133.1 - 0.77 10.2 0.0 0.77 10.2 0.0 3.0 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex Plasmodium_Vir PF05795.11 CDJ56133.1 - 1.1 8.6 14.6 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Myc_N PF01056.18 CDJ56133.1 - 2.9 7.7 19.1 0.25 11.2 14.3 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 CDJ56133.1 - 3.3 7.4 31.8 0.54 9.9 26.2 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.6 CDJ56133.1 - 3.3 7.9 22.6 0.24 11.7 15.7 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Connexin PF00029.19 CDJ56133.1 - 5.1 6.8 10.1 13 5.5 9.5 2.0 2 0 0 2 2 2 0 Connexin Med15 PF09606.10 CDJ56133.1 - 5.9 5.5 43.2 0.15 10.7 1.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 CDJ56133.1 - 6 6.7 22.9 6.5 6.6 17.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FHIPEP PF00771.20 CDJ56133.1 - 9 4.6 8.4 3 6.2 4.6 2.0 2 0 0 2 2 2 0 FHIPEP family FtsJ PF01728.19 CDJ56136.1 - 3e-14 53.5 0.0 7.7e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3446 PF11928.8 CDJ56136.1 - 3.5 8.0 9.9 0.37 11.1 1.2 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain RskA PF10099.9 CDJ56137.1 - 0.0072 16.6 0.9 0.0088 16.4 0.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF5523 PF17661.1 CDJ56137.1 - 0.07 12.8 24.2 0.091 12.4 24.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Mpp10 PF04006.12 CDJ56137.1 - 0.074 11.5 29.4 0.078 11.4 29.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 CDJ56137.1 - 0.11 10.7 31.0 0.12 10.6 31.0 1.0 1 0 0 1 1 1 0 Nop14-like family TraT PF05818.12 CDJ56137.1 - 0.12 12.1 3.4 0.18 11.5 3.4 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Spore_coat_CotO PF14153.6 CDJ56137.1 - 0.14 12.1 24.6 0.16 11.9 24.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO eIF3_subunit PF08597.10 CDJ56137.1 - 0.15 11.9 26.3 0.17 11.7 26.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FmiP_Thoc5 PF09766.9 CDJ56137.1 - 0.16 11.3 14.1 0.16 11.2 14.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 SprA-related PF12118.8 CDJ56137.1 - 0.16 11.1 20.5 0.2 10.8 20.5 1.1 1 0 0 1 1 1 0 SprA-related family ADP_ribosyl_GH PF03747.14 CDJ56137.1 - 0.17 11.6 3.1 0.19 11.5 3.1 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Chorion_3 PF05387.11 CDJ56137.1 - 0.21 11.2 3.7 0.26 10.9 3.7 1.1 1 0 0 1 1 1 0 Chorion family 3 RR_TM4-6 PF06459.12 CDJ56137.1 - 0.3 10.9 20.9 0.36 10.6 20.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NESP55 PF06390.12 CDJ56137.1 - 0.36 10.4 22.4 0.46 10.0 22.4 1.0 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PPP4R2 PF09184.11 CDJ56137.1 - 0.38 10.3 31.7 0.42 10.2 31.7 1.1 1 0 0 1 1 1 0 PPP4R2 XRN_M PF17846.1 CDJ56137.1 - 0.39 9.6 12.1 0.47 9.3 12.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CCSAP PF15748.5 CDJ56137.1 - 0.49 10.5 21.8 0.58 10.3 21.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AAA_11 PF13086.6 CDJ56137.1 - 0.61 9.8 12.2 0.68 9.7 12.2 1.1 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 CDJ56137.1 - 0.7 9.3 32.8 0.77 9.1 32.8 1.1 1 0 0 1 1 1 0 SDA1 Cytomega_UL20A PF05984.12 CDJ56137.1 - 0.74 10.2 5.2 1.2 9.5 5.2 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein VIR_N PF15912.5 CDJ56137.1 - 0.87 9.1 17.0 0.97 9.0 17.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 CDJ56137.1 - 1.1 8.4 14.4 1.3 8.2 14.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SARAF PF06682.12 CDJ56137.1 - 1.2 8.7 11.2 1.4 8.5 11.2 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CDC45 PF02724.14 CDJ56137.1 - 1.5 7.0 22.8 1.7 6.9 22.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 CDJ56137.1 - 1.5 8.2 10.4 1.6 8.2 10.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TFIIA PF03153.13 CDJ56137.1 - 1.7 8.6 20.2 2 8.3 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RPOL_N PF14700.6 CDJ56137.1 - 1.7 7.9 12.5 1.9 7.8 12.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal THOC2_N PF16134.5 CDJ56137.1 - 1.8 7.1 15.3 2.4 6.7 15.3 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Cwf_Cwc_15 PF04889.12 CDJ56137.1 - 1.9 8.2 26.2 2.4 7.8 26.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAF1_ABF1 PF04684.13 CDJ56137.1 - 2.1 7.3 21.2 2.6 7.0 21.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Roughex PF06020.11 CDJ56137.1 - 2.5 7.1 19.4 2.7 7.0 19.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RNA_polI_A34 PF08208.11 CDJ56137.1 - 2.9 7.9 24.3 4 7.5 24.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM60A PF15396.6 CDJ56137.1 - 3.2 7.7 11.4 4.7 7.2 11.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF2828 PF11443.8 CDJ56137.1 - 3.5 5.6 11.6 4.1 5.4 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ureide_permease PF07168.11 CDJ56137.1 - 3.5 6.3 7.9 4.1 6.1 7.9 1.2 1 0 0 1 1 1 0 Ureide permease Paf1 PF03985.13 CDJ56137.1 - 3.7 6.5 32.8 4.9 6.0 32.8 1.3 1 0 0 1 1 1 0 Paf1 PGA2 PF07543.12 CDJ56137.1 - 3.7 7.5 23.3 5.1 7.1 23.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 SID-1_RNA_chan PF13965.6 CDJ56137.1 - 3.7 5.8 6.9 3.8 5.8 6.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC27 PF09507.10 CDJ56137.1 - 4.3 6.6 27.0 5.1 6.4 27.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.16 CDJ56137.1 - 4.5 7.3 10.4 5.8 6.9 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ56137.1 - 4.7 6.2 7.7 4.8 6.1 7.7 1.3 1 0 0 1 1 1 0 CLN3 protein SOG2 PF10428.9 CDJ56137.1 - 4.8 6.3 9.6 5 6.2 9.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CDJ56137.1 - 4.9 6.1 14.1 5.4 5.9 14.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 CDJ56137.1 - 6.3 5.4 17.2 7.1 5.3 17.2 1.0 1 0 0 1 1 1 0 Raftlin Dynamin_N PF00350.23 CDJ56137.1 - 6.4 6.8 8.1 10 6.1 8.1 1.4 1 0 0 1 1 1 0 Dynamin family SAPS PF04499.15 CDJ56137.1 - 6.6 5.4 19.6 7.1 5.3 19.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.11 CDJ56137.1 - 7.2 5.0 12.8 8.7 4.7 12.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CDJ56137.1 - 8.4 5.0 24.7 9.6 4.8 24.7 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 CDJ56137.1 - 8.5 5.9 33.3 11 5.5 33.3 1.2 1 0 0 1 1 1 0 DDRGK domain TCP PF03634.13 CDJ56137.1 - 8.6 6.9 21.1 11 6.6 21.1 1.1 1 0 0 1 1 1 0 TCP family transcription factor HNF-1_N PF04814.13 CDJ56137.1 - 9.4 6.8 16.0 11 6.5 16.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus AAA_lid_10 PF17872.1 CDJ56139.1 - 0.00034 20.7 0.3 0.00039 20.5 0.3 1.2 1 0 0 1 1 1 1 AAA lid domain CDC50 PF03381.15 CDJ56140.1 - 1.1e-27 97.3 0.0 2.3e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Roughex PF06020.11 CDJ56140.1 - 0.24 10.5 1.8 0.42 9.7 1.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 CDJ56140.1 - 0.49 10.0 14.9 1.2 8.6 14.9 1.6 1 0 0 1 1 1 0 Spt20 family NACHT_N PF17100.5 CDJ56140.1 - 0.91 9.3 5.8 15 5.3 6.3 2.2 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Acatn PF13000.7 CDJ56141.1 - 3.4e-50 171.1 0.3 2.5e-31 108.8 0.0 2.4 2 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 OATP PF03137.20 CDJ56141.1 - 0.00017 20.1 0.0 0.00022 19.7 0.0 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.13 CDJ56141.1 - 0.0038 17.3 8.0 0.0042 17.1 8.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.6 CDJ56141.1 - 0.014 15.8 0.2 0.021 15.2 0.2 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 TIMELESS PF04821.14 CDJ56141.1 - 0.024 13.9 0.4 0.032 13.5 0.4 1.1 1 0 0 1 1 1 0 Timeless protein TssO PF17561.2 CDJ56141.1 - 0.038 14.1 3.8 0.058 13.5 3.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF5320 PF17253.2 CDJ56141.1 - 0.077 14.1 0.1 0.14 13.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) EphA2_TM PF14575.6 CDJ56141.1 - 0.082 13.8 0.0 0.15 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 CDJ56141.1 - 0.094 13.4 0.7 0.67 10.6 0.1 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 FAM209 PF15206.6 CDJ56141.1 - 0.099 12.4 0.5 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 FAM209 family DUF4834 PF16118.5 CDJ56141.1 - 0.11 13.5 1.5 0.17 12.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ56141.1 - 0.23 10.3 14.5 0.31 10.0 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ56141.1 - 2.1 7.9 19.6 3 7.4 19.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 CDJ56141.1 - 8.3 5.7 8.4 12 5.2 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.8 CDJ56142.1 - 0.00037 19.8 25.2 0.00037 19.8 25.2 5.7 3 2 1 5 5 5 1 SprA-related family DsrH PF04077.12 CDJ56142.1 - 0.15 12.2 0.2 0.15 12.2 0.2 3.5 3 0 0 3 3 3 0 DsrH like protein Aconitase_2_N PF06434.13 CDJ56142.1 - 0.21 11.2 5.9 2.6 7.6 0.1 3.0 2 1 1 3 3 3 0 Aconitate hydratase 2 N-terminus TRAP-gamma PF07074.12 CDJ56143.1 - 0.54 9.8 1.5 0.81 9.2 1.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LSM PF01423.22 CDJ56144.1 - 2e-16 59.4 0.5 3.9e-16 58.5 0.5 1.5 1 0 0 1 1 1 1 LSM domain SPX PF03105.19 CDJ56144.1 - 0.011 15.7 14.5 0.011 15.7 14.5 2.2 2 0 0 2 2 2 0 SPX domain Nha1_C PF08619.10 CDJ56144.1 - 0.22 10.7 40.5 0.0093 15.2 15.9 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus THAP PF05485.12 CDJ56144.1 - 1.1 10.3 0.0 1.1 10.3 0.0 3.5 4 1 0 4 4 4 0 THAP domain SDA1 PF05285.12 CDJ56145.1 - 0.0026 17.3 4.8 0.0038 16.7 4.8 1.1 1 0 0 1 1 1 1 SDA1 SPX PF03105.19 CDJ56145.1 - 0.0056 16.6 6.8 0.0056 16.6 6.8 1.8 2 0 0 2 2 2 1 SPX domain Lin-8 PF03353.15 CDJ56145.1 - 0.0076 15.9 9.5 0.011 15.3 9.5 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ56145.1 - 0.012 14.5 10.0 0.02 13.7 10.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 CDJ56145.1 - 0.17 11.3 5.9 0.23 10.8 5.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.15 CDJ56145.1 - 0.32 9.7 3.6 0.43 9.3 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CDJ56145.1 - 0.41 9.4 10.8 0.58 8.9 10.8 1.2 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 CDJ56145.1 - 0.49 8.4 5.5 1 7.4 5.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 CDJ56145.1 - 1.5 7.0 9.2 2.8 6.1 9.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 CDJ56145.1 - 2.6 6.4 11.5 3.5 6.0 11.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Pex14_N PF04695.13 CDJ56145.1 - 2.9 8.5 10.8 8.5 7.0 6.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 CDJ56145.1 - 5.2 6.0 6.0 7.5 5.5 6.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ56145.1 - 7.5 6.3 9.7 13 5.5 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CDJ56145.1 - 8.1 5.1 10.0 13 4.4 10.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ56146.1 - 0.006 16.2 23.0 0.006 16.2 23.0 3.9 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein MAT1 PF06391.13 CDJ56146.1 - 5.6 6.7 15.2 0.31 10.9 5.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Carboxyl_trans PF01039.22 CDJ56149.1 - 2.2e-152 508.1 0.0 4.4e-152 507.2 0.0 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDJ56149.1 - 7.2e-46 156.3 0.0 2.9e-25 89.0 0.0 2.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDJ56149.1 - 5.3e-27 94.6 0.2 2.6e-21 76.2 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDJ56149.1 - 1.7e-20 73.1 0.0 4.5e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CDJ56149.1 - 6.5e-16 57.7 3.5 8.1e-10 37.6 0.2 3.2 2 1 1 3 3 3 3 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 CDJ56149.1 - 1.1e-10 41.2 0.0 2.9e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ56149.1 - 2.5e-05 24.0 0.5 0.00098 18.9 0.0 3.2 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 CDJ56149.1 - 4.3e-05 23.1 0.2 0.13 11.8 0.0 3.5 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDJ56149.1 - 0.0048 16.4 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDJ56149.1 - 0.049 13.7 0.0 0.69 10.0 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain ATG_C PF09333.11 CDJ56150.1 - 4.8e-06 26.8 0.1 2.8e-05 24.4 0.0 2.3 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ56150.1 - 0.0045 16.8 2.2 3.7 7.3 0.1 3.3 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ56151.1 - 1.4e-09 37.7 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 CDJ56152.1 - 3.9e-29 101.1 0.1 3.9e-29 101.1 0.1 3.6 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ56152.1 - 1.1e-14 54.8 0.0 9.2e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal CENP-B_dimeris PF09026.10 CDJ56152.1 - 0.24 11.8 2.2 1.3 9.4 2.2 2.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L11_N PF03946.14 CDJ56153.1 - 2.3e-21 75.4 0.1 3.5e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ56153.1 - 6e-17 61.9 0.2 9.7e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain gerPA PF10676.9 CDJ56153.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF Ribosomal_L30_N PF08079.12 CDJ56154.1 - 7.9e-16 58.1 13.9 7.9e-16 58.1 13.9 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CDJ56154.1 - 2.1e-14 53.1 0.7 4.1e-14 52.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S8e PF01201.22 CDJ56154.1 - 0.047 13.9 1.3 0.065 13.4 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e DUF2457 PF10446.9 CDJ56155.1 - 0.015 14.5 3.6 0.015 14.5 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hepatitis_core PF00906.20 CDJ56155.1 - 0.34 10.4 5.4 0.36 10.4 5.4 1.1 1 0 0 1 1 1 0 Hepatitis core antigen DTC PF18102.1 CDJ56156.1 - 6.2e-42 142.9 0.0 1.1e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 CDJ56156.1 - 8.7e-07 29.4 5.6 0.03 14.9 0.0 4.4 6 0 0 6 6 6 2 WWE domain CobT PF06213.12 CDJ56156.1 - 6.7 6.0 10.8 13 5.1 10.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_S19e PF01090.19 CDJ56157.1 - 1.4e-50 170.6 0.0 1.7e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 CDJ56157.1 - 0.0015 18.4 0.6 0.003 17.5 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain MarR_2 PF12802.7 CDJ56157.1 - 0.11 12.5 0.1 0.83 9.6 0.0 2.4 3 0 0 3 3 3 0 MarR family AP_endonuc_2 PF01261.24 CDJ56158.1 - 4.6e-30 104.6 0.0 6.5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fe-S_biosyn PF01521.20 CDJ56159.1 - 1.6e-07 31.5 0.1 0.00015 21.9 0.0 2.5 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis AAA_5 PF07728.14 CDJ56160.1 - 9.6e-105 346.3 0.0 1.7e-20 73.4 0.0 11.8 11 1 0 11 11 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ56160.1 - 1.3e-25 89.6 5.8 1.3e-11 44.7 0.4 4.3 3 0 0 3 3 3 2 Midasin AAA lid domain AAA PF00004.29 CDJ56160.1 - 1.3e-21 77.4 0.0 0.01 16.3 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CDJ56160.1 - 1.7e-18 66.7 0.0 0.00039 20.3 0.0 6.6 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CDJ56160.1 - 2.8e-18 65.9 0.0 7.4e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_22 PF13401.6 CDJ56160.1 - 2.3e-16 60.3 0.0 0.018 15.3 0.0 7.5 7 0 0 7 7 6 3 AAA domain Dynein_heavy PF03028.15 CDJ56160.1 - 2.4e-15 56.6 0.0 0.00024 21.2 0.0 5.9 5 0 0 5 5 5 3 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 CDJ56160.1 - 5.1e-13 48.9 0.0 0.11 11.9 0.0 6.4 6 0 0 6 6 6 4 P-loop containing dynein motor region TsaE PF02367.17 CDJ56160.1 - 5.3e-13 49.1 0.7 1.1 9.3 0.1 6.4 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CDJ56160.1 - 1.9e-11 44.3 8.2 0.0072 16.5 0.0 7.9 8 0 0 8 8 6 2 AAA domain AAA_18 PF13238.6 CDJ56160.1 - 7.6e-10 39.4 0.0 1.3 9.6 0.0 7.4 7 0 0 7 7 6 1 AAA domain ABC_tran PF00005.27 CDJ56160.1 - 3.4e-09 37.3 0.0 1.2 9.6 0.0 6.8 6 0 0 6 6 6 2 ABC transporter AAA_16 PF13191.6 CDJ56160.1 - 5.8e-09 36.6 77.5 0.0043 17.5 1.0 14.5 12 2 1 13 13 7 6 AAA ATPase domain Zeta_toxin PF06414.12 CDJ56160.1 - 2.9e-07 30.0 0.1 7.8 5.7 0.0 6.2 6 0 0 6 6 6 0 Zeta toxin Mg_chelatase PF01078.21 CDJ56160.1 - 1e-06 28.3 5.4 0.12 11.8 0.0 7.1 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CDJ56160.1 - 5.1e-06 26.6 1.1 2.7 8.1 0.0 6.0 5 0 0 5 5 5 1 Sigma-54 interaction domain DUF815 PF05673.13 CDJ56160.1 - 5.2e-06 25.8 2.4 0.057 12.6 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 CDJ56160.1 - 7.7e-06 25.6 0.2 4.1 7.2 0.0 6.1 6 0 0 6 6 6 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CDJ56160.1 - 2.5e-05 24.1 0.3 6.8 6.4 0.0 6.1 7 0 0 7 7 6 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CDJ56160.1 - 2.8e-05 24.4 0.0 30 5.1 0.0 6.1 6 0 0 6 6 6 0 RNA helicase AAA_6 PF12774.7 CDJ56160.1 - 3.1e-05 23.1 0.1 0.71 8.8 0.0 5.5 6 0 0 6 6 6 1 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 CDJ56160.1 - 5.2e-05 23.2 4.6 3.4 7.5 0.0 6.8 7 0 0 7 7 5 1 NACHT domain AAA_8 PF12780.7 CDJ56160.1 - 0.00014 21.2 0.0 0.67 9.2 0.0 4.7 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 RuvB_N PF05496.12 CDJ56160.1 - 0.00075 19.3 0.6 16 5.2 0.0 5.8 7 0 0 7 7 6 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDJ56160.1 - 0.0011 18.9 1.0 2.2 8.2 0.0 4.2 5 0 0 5 5 4 1 Rad17 P-loop domain ResIII PF04851.15 CDJ56160.1 - 0.0018 18.3 0.0 11 6.0 0.0 3.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CDJ56160.1 - 0.0022 17.9 0.1 6.1 6.7 0.0 4.5 4 0 0 4 4 4 0 RsgA GTPase AAA_25 PF13481.6 CDJ56160.1 - 0.0033 17.0 9.1 13 5.2 0.5 6.5 6 0 0 6 6 6 0 AAA domain T2SSE PF00437.20 CDJ56160.1 - 0.005 15.9 0.0 1.1 8.3 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein DEAD PF00270.29 CDJ56160.1 - 0.032 14.0 0.2 2.4 7.9 0.0 3.8 4 0 0 4 4 4 0 DEAD/DEAH box helicase VWA PF00092.28 CDJ56160.1 - 0.037 14.3 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Viral_helicase1 PF01443.18 CDJ56160.1 - 0.053 13.2 0.0 0.59 9.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CDJ56160.1 - 0.069 12.8 0.0 57 3.3 0.0 4.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain dNK PF01712.19 CDJ56160.1 - 0.17 11.7 1.0 8.8 6.1 0.0 4.0 6 0 0 6 6 4 0 Deoxynucleoside kinase DUF3185 PF11381.8 CDJ56160.1 - 0.18 11.9 0.0 2.5 8.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Lipase_3 PF01764.25 CDJ56161.1 - 2.8e-13 50.0 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CDJ56161.1 - 0.0045 16.5 0.1 0.0073 15.8 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 CDJ56161.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HATPase_c PF02518.26 CDJ56162.1 - 1.4e-05 25.5 0.0 0.0007 20.1 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DHC_N1 PF08385.12 CDJ56163.1 - 9e-121 404.2 14.6 5.4e-82 276.2 9.5 2.9 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 Baculo_PEP_C PF04513.12 CDJ56163.1 - 0.0014 18.7 0.9 3.3 7.7 1.1 3.4 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus GCP_N_terminal PF17681.1 CDJ56163.1 - 0.02 14.5 1.7 0.035 13.7 0.3 2.2 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal FTO_CTD PF12934.7 CDJ56163.1 - 0.041 13.7 1.5 11 5.8 0.0 3.5 3 0 0 3 3 3 0 FTO C-terminal domain PBC PF03792.13 CDJ56163.1 - 0.054 13.3 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 PBC domain APG6_N PF17675.1 CDJ56164.1 - 0.16 12.5 7.3 0.19 12.3 7.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region betaPIX_CC PF16523.5 CDJ56164.1 - 0.87 9.5 9.2 0.81 9.6 7.8 1.6 2 0 0 2 2 2 0 betaPIX coiled coil FmdE PF02663.14 CDJ56164.1 - 1.8 8.6 4.8 2.3 8.3 4.5 1.3 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Proteasome PF00227.26 CDJ56165.1 - 1.7e-50 171.1 0.0 2.1e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ56165.1 - 3.8e-11 42.4 0.0 6.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature V_ATPase_I PF01496.19 CDJ56166.1 - 6.1e-174 580.1 0.0 1.4e-68 231.7 0.0 3.2 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family Androgen_recep PF02166.16 CDJ56166.1 - 0.0035 16.2 3.0 0.0035 16.2 3.0 5.3 5 1 1 6 6 6 1 Androgen receptor Spore_III_AB PF09548.10 CDJ56166.1 - 0.0047 17.1 0.1 0.014 15.5 0.1 1.8 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Kelch_1 PF01344.25 CDJ56168.1 - 1.5e-45 152.5 2.7 3.1e-09 36.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDJ56168.1 - 4.5e-30 102.5 18.4 4.7e-06 26.4 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CDJ56168.1 - 1e-29 101.8 10.2 6.5e-06 26.2 0.0 6.6 3 3 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CDJ56168.1 - 1.1e-27 95.8 13.0 2.9e-06 27.2 0.1 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ56168.1 - 5.1e-27 93.4 5.1 2.8e-05 24.0 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 CDJ56168.1 - 1.1e-26 92.6 26.4 4.5e-05 23.6 0.1 9.6 11 0 0 11 11 11 6 Galactose oxidase, central domain BTB PF00651.31 CDJ56168.1 - 1.2e-14 54.5 0.0 2.1e-13 50.5 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Cript PF10235.9 CDJ56169.1 - 2.2e-15 57.0 6.9 2.2e-15 57.0 6.9 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 CDJ56169.1 - 0.02 14.9 6.9 0.15 12.1 3.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 CDJ56169.1 - 0.041 14.6 7.8 0.058 14.1 4.0 2.5 2 1 0 2 2 2 0 zinc-ribbon family C6_DPF PF10170.9 CDJ56169.1 - 0.31 11.5 6.3 0.85 10.0 6.3 2.0 1 1 0 1 1 1 0 Cysteine-rich domain zf-FCS PF06467.14 CDJ56169.1 - 0.37 10.8 0.3 0.37 10.8 0.3 2.9 2 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Sar8_2 PF03058.14 CDJ56169.1 - 1.3 9.6 13.2 19 5.9 13.2 2.2 1 1 0 1 1 1 0 Sar8.2 family DiS_P_DiS PF06750.13 CDJ56169.1 - 3.8 7.7 9.6 2.3 8.4 5.2 2.5 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain EF-hand_1 PF00036.32 CDJ56170.1 - 1.1e-19 68.4 6.1 1.1e-07 30.9 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ56170.1 - 3e-19 69.2 3.0 7.8e-16 58.3 1.0 2.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ56170.1 - 5.7e-17 61.3 7.4 1.4e-11 44.1 0.2 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ56170.1 - 1e-14 53.1 6.8 8.9e-05 22.1 0.1 3.7 3 1 1 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 CDJ56170.1 - 5.8e-09 36.1 0.1 6.9e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDJ56170.1 - 1.4e-07 30.7 11.0 1.7e-05 24.1 0.3 3.7 3 1 1 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDJ56170.1 - 6.4e-05 22.9 1.1 0.0037 17.2 0.1 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF3008 PF11450.8 CDJ56170.1 - 0.0025 18.0 1.9 0.0034 17.5 0.4 1.8 2 0 0 2 2 2 1 Protein of unknwon function (DUF3008) DUF150 PF02576.17 CDJ56170.1 - 0.046 14.1 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 RimP N-terminal domain SPARC_Ca_bdg PF10591.9 CDJ56170.1 - 0.11 12.8 0.0 0.26 11.6 0.1 1.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Vps39_2 PF10367.9 CDJ56171.1 - 7.3e-18 65.0 0.0 7.3e-18 65.0 0.0 3.6 4 0 0 4 4 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CDJ56171.1 - 7.8e-09 35.5 0.3 2.2e-07 30.9 0.3 3.0 1 1 1 2 2 2 1 Region in Clathrin and VPS Spt20 PF12090.8 CDJ56171.1 - 0.0016 18.1 5.8 0.0016 18.1 5.8 3.7 2 1 0 2 2 1 1 Spt20 family DUF2722 PF10846.8 CDJ56171.1 - 0.0041 16.1 1.4 0.0041 16.1 1.4 3.4 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ56171.1 - 0.0098 16.2 1.0 0.0098 16.2 1.0 5.9 4 1 0 5 5 4 2 Anti-sigma-K factor rskA DUF4265 PF14085.6 CDJ56171.1 - 0.066 13.2 1.8 0.15 12.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) 7tm_1 PF00001.21 CDJ56171.1 - 0.41 9.9 1.6 12 5.1 0.2 2.5 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) Suf PF05843.14 CDJ56171.1 - 0.55 10.2 24.2 1.3 9.0 0.7 2.8 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ56171.1 - 1.1 8.0 9.5 4.5 5.9 4.2 2.3 2 0 0 2 2 2 0 Presenilin DUF3499 PF12005.8 CDJ56171.1 - 1.5 9.4 9.2 1.9 9.1 1.5 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3499) ORC_WH_C PF18137.1 CDJ56171.1 - 1.7 8.7 8.9 4.9 7.2 4.0 2.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal PH_4 PF15404.6 CDJ56171.1 - 4.1 7.2 6.9 4.3 7.1 1.6 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Orf78 PF06024.12 CDJ56171.1 - 6.1 7.2 6.9 16 5.8 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) TFB6 PF17110.5 CDJ56171.1 - 9.1 6.0 6.6 45 3.7 3.9 2.5 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SUIM_assoc PF16619.5 CDJ56172.1 - 0.008 16.2 1.5 0.008 16.2 1.5 10.3 4 3 5 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 LMBR1 PF04791.16 CDJ56174.1 - 0.024 13.6 11.0 0.037 12.9 11.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribonuc_red_lgC PF02867.15 CDJ56176.1 - 3.4e-08 32.5 0.2 4.5e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Aldolase PF01081.19 CDJ56176.1 - 0.0044 16.5 0.5 0.0063 16.0 0.5 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase DUF4644 PF15486.6 CDJ56176.1 - 0.25 11.1 2.3 0.22 11.3 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) TAF4 PF05236.14 CDJ56176.1 - 7.8 6.2 7.3 11 5.6 7.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Herpes_LMP1 PF05297.11 CDJ56177.1 - 2.9 7.0 5.0 3.7 6.7 5.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Fes1 PF08609.10 CDJ56178.1 - 0.035 15.0 17.0 0.2 12.5 4.2 4.2 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 PUNUT PF16913.5 CDJ56178.1 - 0.036 13.3 0.2 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Velvet PF11754.8 CDJ56178.1 - 0.039 13.9 5.0 0.15 12.0 3.4 2.3 2 0 0 2 2 2 0 Velvet factor TAF6_C PF07571.13 CDJ56178.1 - 0.067 13.5 0.5 0.71 10.2 0.1 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Abhydrolase_1 PF00561.20 CDJ56178.1 - 0.19 11.3 1.3 0.36 10.4 1.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2722 PF10846.8 CDJ56178.1 - 0.53 9.2 37.4 0.25 10.2 16.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Serinc PF03348.15 CDJ56178.1 - 0.55 9.1 3.8 1.5 7.7 3.8 1.7 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ipi1_N PF12333.8 CDJ56178.1 - 0.93 10.1 8.2 6.1 7.5 0.9 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation V_ATPase_I PF01496.19 CDJ56178.1 - 1 7.2 7.1 1.7 6.5 5.9 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CDJ56178.1 - 4 7.2 14.3 0.14 11.9 6.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ56178.1 - 4 7.4 9.5 6.3 6.8 6.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ56178.1 - 4.5 5.9 9.3 1.1 8.0 4.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PRP1_N PF06424.12 CDJ56178.1 - 4.6 7.6 12.5 1.6 9.1 5.3 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Connexin PF00029.19 CDJ56178.1 - 4.9 6.8 7.5 1.2 8.8 3.4 1.9 2 0 0 2 2 2 0 Connexin Gti1_Pac2 PF09729.9 CDJ56178.1 - 8.2 6.5 8.0 15 5.6 6.3 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family CSG2 PF16965.5 CDJ56178.1 - 8.8 5.1 6.6 21 3.9 4.7 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator PPP4R2 PF09184.11 CDJ56179.1 - 0.1 12.2 5.7 0.21 11.2 5.7 1.4 1 0 0 1 1 1 0 PPP4R2 CPSF100_C PF13299.6 CDJ56179.1 - 1.7 8.8 6.8 6.6 6.9 5.2 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PTPRCAP PF15713.5 CDJ56179.1 - 2.9 8.2 19.0 1.1 9.5 14.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TRM PF02005.16 CDJ56180.1 - 2.4e-78 264.0 0.0 5.5e-76 256.2 0.0 2.0 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TMA7 PF09072.10 CDJ56180.1 - 0.011 16.6 8.5 0.011 16.6 8.5 3.2 3 0 0 3 3 3 0 Translation machinery associated TMA7 GETHR PF05671.11 CDJ56180.1 - 0.024 14.0 0.3 0.05 13.0 0.3 1.5 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) CpXC PF14353.6 CDJ56180.1 - 0.086 12.9 0.7 0.38 10.8 0.2 2.1 2 0 0 2 2 2 0 CpXC protein FYDLN_acid PF09538.10 CDJ56180.1 - 0.13 13.0 4.5 0.1 13.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1178 PF06676.11 CDJ56180.1 - 0.18 12.2 4.8 0.51 10.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) PrmA PF06325.13 CDJ56180.1 - 0.19 11.1 0.1 0.39 10.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FAM176 PF14851.6 CDJ56180.1 - 0.31 10.7 3.3 0.15 11.7 0.4 1.9 2 0 0 2 2 2 0 FAM176 family RNA_pol_Rbc25 PF08292.12 CDJ56180.1 - 0.44 10.8 3.6 0.21 11.8 0.3 2.1 3 0 0 3 3 2 0 RNA polymerase III subunit Rpc25 DUF4834 PF16118.5 CDJ56180.1 - 1.2 10.2 4.9 0.46 11.5 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spore_coat_CotO PF14153.6 CDJ56180.1 - 1.9 8.4 10.6 0.11 12.4 5.0 1.8 2 0 0 2 2 2 0 Spore coat protein CotO PBP1_TM PF14812.6 CDJ56180.1 - 3.2 8.2 5.4 0.87 10.0 1.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt20 PF12090.8 CDJ56180.1 - 7 6.2 12.1 15 5.1 12.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ56181.1 - 2.3e-05 23.5 1.0 2.3e-05 23.5 1.0 11.9 10 3 0 10 10 10 4 Protein of unknown function (DUF2722) RNA_pol_Rpc4 PF05132.14 CDJ56182.1 - 1.7 9.1 10.8 1.1 9.6 4.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 CDJ56182.1 - 5.3 7.2 16.8 1 9.5 5.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Tho2 PF11262.8 CDJ56183.1 - 3e-12 46.4 11.1 1.7e-07 30.8 0.2 3.3 2 1 1 3 3 3 2 Transcription factor/nuclear export subunit protein 2 DUF4667 PF15700.5 CDJ56183.1 - 0.053 13.6 0.0 0.053 13.6 0.0 11.1 3 3 3 8 8 8 0 Domain of unknown function (DUF4667) SPX PF03105.19 CDJ56183.1 - 1.8 8.4 0.0 1.8 8.4 0.0 6.8 2 2 3 5 5 5 0 SPX domain Connexin PF00029.19 CDJ56184.1 - 0.16 11.7 8.5 6.6 6.4 0.2 3.7 4 0 0 4 4 4 0 Connexin DUF2722 PF10846.8 CDJ56184.1 - 0.71 8.8 29.6 0.32 9.9 16.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) PAT1 PF09770.9 CDJ56184.1 - 7.4 4.7 22.6 13 3.9 22.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_pp85 PF04637.12 CDJ56184.1 - 8.5 4.7 9.1 15 3.8 9.1 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4834 PF16118.5 CDJ56184.1 - 9.9 7.2 25.2 11 7.0 8.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Metallophos PF00149.28 CDJ56187.1 - 2.3e-09 38.1 0.0 3.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUIM_assoc PF16619.5 CDJ56187.1 - 0.00084 19.4 1.9 0.00084 19.4 1.9 3.4 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 RPN2_C PF18004.1 CDJ56187.1 - 0.018 15.0 20.8 0.018 15.0 20.8 2.9 3 1 1 4 4 4 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 CDJ56187.1 - 0.023 14.1 42.3 0.063 12.6 34.8 2.1 2 0 0 2 2 2 0 BUD22 DUF3446 PF11928.8 CDJ56187.1 - 2.4 8.5 37.6 0.15 12.3 8.8 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain SPX PF03105.19 CDJ56187.1 - 2.4 8.0 32.9 6.7 6.5 0.1 2.1 2 0 0 2 2 2 0 SPX domain OAD_gamma PF04277.13 CDJ56187.1 - 7.7 7.2 13.7 2.4 8.8 0.1 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_L17 PF01196.19 CDJ56188.1 - 2.7e-16 60.2 0.2 3.3e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 DUF1682 PF07946.14 CDJ56189.1 - 0.0038 16.5 7.8 0.0043 16.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Topoisom_I_N PF02919.15 CDJ56189.1 - 0.05 13.1 8.0 0.056 12.9 8.0 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RR_TM4-6 PF06459.12 CDJ56189.1 - 0.37 10.6 13.7 0.41 10.4 13.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CDJ56189.1 - 1.2 8.5 18.7 1.4 8.3 18.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDJ56189.1 - 2.8 7.3 14.7 3.1 7.2 14.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 CDJ56189.1 - 4.6 7.1 15.4 4.8 7.1 15.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LMBR1 PF04791.16 CDJ56189.1 - 4.8 6.0 10.7 5.1 5.9 10.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CDJ56189.1 - 6.4 5.4 15.1 6.8 5.3 15.1 1.0 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ56189.1 - 6.4 6.7 6.8 7 6.5 6.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein Spt20 PF12090.8 CDJ56189.1 - 6.6 6.3 30.8 8.7 5.9 30.8 1.2 1 0 0 1 1 1 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ56189.1 - 9.3 6.0 10.3 11 5.6 10.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FUSC PF04632.12 CDJ56190.1 - 0.00076 18.2 16.4 0.00096 17.8 16.4 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family PAP2 PF01569.21 CDJ56190.1 - 0.023 14.5 0.2 0.023 14.5 0.2 1.9 2 0 0 2 2 2 0 PAP2 superfamily Plasmodium_Vir PF05795.11 CDJ56190.1 - 0.14 11.6 8.8 0.19 11.1 8.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AbLIM_anchor PF16182.5 CDJ56190.1 - 0.16 11.8 13.9 0.2 11.5 13.9 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM Herpes_UL74 PF07982.12 CDJ56190.1 - 0.2 10.6 2.3 0.33 9.9 2.3 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins CCSAP PF15748.5 CDJ56190.1 - 0.41 10.8 29.8 0.51 10.5 29.8 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3292 PF11696.8 CDJ56190.1 - 0.88 7.9 16.9 1.2 7.5 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) NAD_kinase PF01513.21 CDJ56190.1 - 0.91 8.7 6.0 1.6 7.9 6.0 1.5 1 1 0 1 1 1 0 ATP-NAD kinase Draxin PF15550.6 CDJ56190.1 - 0.92 9.3 15.4 1.1 9.0 15.4 1.1 1 0 0 1 1 1 0 Draxin DUF5427 PF10310.9 CDJ56190.1 - 1.7 7.6 27.6 2.2 7.1 27.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) AvrE_T3Es PF11725.8 CDJ56190.1 - 1.9 5.6 14.0 2.2 5.4 14.0 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) CDC45 PF02724.14 CDJ56190.1 - 3.3 5.9 23.2 3.8 5.7 23.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Piezo_RRas_bdg PF12166.8 CDJ56190.1 - 3.5 6.8 11.7 5 6.3 11.7 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain LMBR1 PF04791.16 CDJ56190.1 - 3.7 6.4 14.2 4.3 6.1 14.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LAP1C PF05609.12 CDJ56190.1 - 4.1 6.4 24.6 5 6.1 24.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PDDEXK_6 PF04720.12 CDJ56190.1 - 5.1 7.0 14.9 6.5 6.6 14.9 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Peptidase_S64 PF08192.11 CDJ56190.1 - 5.6 5.3 19.9 7.4 4.9 19.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 DEAD PF00270.29 CDJ56191.1 - 0.0087 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5523 PF17661.1 CDJ56191.1 - 0.15 11.8 4.3 0.15 11.7 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4672 PF15716.5 CDJ56191.1 - 0.72 9.4 3.1 0.9 9.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) Bromodomain PF00439.25 CDJ56192.1 - 1.5e-05 24.9 0.1 4.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Bromodomain DUF2281 PF10047.9 CDJ56192.1 - 0.023 15.4 0.0 0.074 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Apt1 PF10351.9 CDJ56192.1 - 0.096 11.5 10.1 0.14 11.0 2.4 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain vATP-synt_AC39 PF01992.16 CDJ56193.1 - 2.2e-60 204.9 3.2 2.6e-60 204.7 3.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CBP_BcsG PF11658.8 CDJ56193.1 - 0.0014 17.1 0.1 0.0019 16.7 0.1 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG SSXT PF05030.12 CDJ56194.1 - 8.7e-05 22.1 0.2 8.7e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Spt20 PF12090.8 CDJ56194.1 - 0.0082 15.8 10.0 0.0082 15.8 10.0 2.2 2 0 0 2 2 2 1 Spt20 family Ndc1_Nup PF09531.10 CDJ56194.1 - 0.79 8.3 9.4 1.1 7.9 9.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NUDE_C PF04880.13 CDJ56194.1 - 4.2 7.8 9.6 9.4 6.7 9.6 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ORC3_N PF07034.11 CDJ56195.1 - 1.7e-09 37.2 7.1 1.7e-09 37.2 7.1 5.1 4 1 0 4 4 4 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CDJ56195.1 - 2e-05 24.7 0.0 2e-05 24.7 0.0 6.4 6 1 0 6 6 6 1 Origin recognition complex winged helix C-terminal Spt20 PF12090.8 CDJ56195.1 - 0.014 15.0 0.9 0.014 15.0 0.9 7.1 5 2 0 5 5 5 0 Spt20 family Tetraspanin PF00335.20 CDJ56195.1 - 0.29 10.8 10.7 2 8.0 0.4 3.3 3 0 0 3 3 3 0 Tetraspanin family PAPS_reduct PF01507.19 CDJ56195.1 - 0.84 9.7 4.9 0.8 9.7 0.3 2.8 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Calici_coat_C PF08435.11 CDJ56195.1 - 4.2 6.8 11.6 0.045 13.3 0.6 3.0 3 0 0 3 3 3 0 Calicivirus coat protein C-terminal DUF3657 PF12394.8 CDJ56196.1 - 0.51 10.9 0.0 0.51 10.9 0.0 5.0 5 0 0 5 5 5 0 Protein FAM135 RAP1 PF07218.11 CDJ56196.1 - 3.1 6.0 10.4 4.6 5.4 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.13 CDJ56197.1 - 6.9e-05 23.0 42.4 9.5e-05 22.6 42.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mpp10 PF04006.12 CDJ56197.1 - 0.092 11.2 55.6 0.11 10.9 29.9 2.0 2 0 0 2 2 2 0 Mpp10 protein Dapper PF15268.6 CDJ56197.1 - 0.39 9.5 24.6 0.47 9.2 24.6 1.2 1 0 0 1 1 1 0 Dapper DUF4551 PF15087.6 CDJ56197.1 - 1.1 8.0 21.7 1.5 7.6 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Spt20 PF12090.8 CDJ56199.1 - 1.4e-05 24.8 12.3 1.4e-05 24.8 12.3 2.1 2 0 0 2 2 2 1 Spt20 family Endonuclease_NS PF01223.23 CDJ56199.1 - 0.00011 22.0 3.2 0.0081 16.0 0.0 2.6 3 0 0 3 3 2 2 DNA/RNA non-specific endonuclease SARAF PF06682.12 CDJ56199.1 - 0.011 15.4 2.4 0.011 15.4 2.4 1.9 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 CDJ56199.1 - 0.065 13.2 25.9 0.14 12.1 15.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ56199.1 - 0.31 10.0 17.2 1.2 8.0 11.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 CDJ56199.1 - 1.9 9.3 9.1 2.2 9.1 0.2 2.8 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Tcf25 PF04910.14 CDJ56199.1 - 2.6 7.0 7.8 4 6.4 7.8 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Presenilin PF01080.17 CDJ56199.1 - 3 6.5 14.0 0.5 9.1 9.2 1.8 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 CDJ56199.1 - 4.6 6.2 12.8 2.9 6.8 10.3 1.7 2 0 0 2 2 2 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 CDJ56199.1 - 4.9 7.2 16.8 1.8 8.6 2.0 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Activator_LAG-3 PF11498.8 CDJ56199.1 - 6.7 5.6 29.2 0.24 10.3 14.6 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Utp14 PF04615.13 CDJ56200.1 - 0.6 8.6 56.0 0.73 8.3 56.0 1.0 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.6 CDJ56200.1 - 1.3 7.8 46.2 1.6 7.5 46.2 1.1 1 0 0 1 1 1 0 Dapper SOBP PF15279.6 CDJ56200.1 - 4.6 7.8 34.3 6.5 7.3 34.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ56200.1 - 5.6 5.5 40.7 6.6 5.3 40.7 1.1 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 CDJ56200.1 - 6.1 5.9 34.5 7.8 5.6 34.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDK5_activator PF03261.15 CDJ56200.1 - 6.8 6.1 32.1 8.6 5.8 32.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RNA_pol_A_bac PF01000.26 CDJ56202.1 - 3.6e-11 43.4 0.0 6.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDJ56202.1 - 0.018 14.5 0.1 0.02 14.3 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain PPP4R2 PF09184.11 CDJ56203.1 - 6.1 6.3 69.9 3.8 7.0 49.9 2.2 2 0 0 2 2 2 0 PPP4R2 EMG1 PF03587.14 CDJ56204.1 - 7.3e-15 55.1 4.4 1.9e-06 27.7 0.1 4.4 4 1 0 4 4 4 3 EMG1/NEP1 methyltransferase RskA PF10099.9 CDJ56204.1 - 0.07 13.4 73.6 0.14 12.4 0.0 6.0 3 2 1 5 5 5 0 Anti-sigma-K factor rskA Tim54 PF11711.8 CDJ56204.1 - 5.6 5.6 37.9 0.19 10.5 2.6 3.9 4 0 0 4 4 4 0 Inner membrane protein import complex subunit Tim54 Cwf_Cwc_15 PF04889.12 CDJ56204.1 - 7.5 6.2 49.9 2.7 7.7 1.2 5.3 5 0 0 5 5 5 0 Cwf15/Cwc15 cell cycle control protein PP2C PF00481.21 CDJ56205.1 - 8.3e-29 101.0 2.2 2e-21 76.8 0.2 4.0 2 2 2 4 4 4 3 Protein phosphatase 2C RskA PF10099.9 CDJ56205.1 - 4.2e-05 23.9 10.8 4.2e-05 23.9 10.8 4.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ56205.1 - 8.4 4.8 36.3 19 3.6 36.3 1.5 1 0 0 1 1 1 0 Utp14 protein tRNA-synt_1e PF01406.19 CDJ56206.1 - 4.6e-63 213.4 0.2 4.6e-63 213.4 0.2 2.3 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CDJ56206.1 - 6.4e-06 25.2 0.1 1.5e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 CDJ56206.1 - 0.0038 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 CDJ56206.1 - 0.0066 14.8 0.6 0.035 12.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF3886 PF13025.6 CDJ56206.1 - 0.25 11.6 23.7 0.05 13.8 2.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) SpoIIIAH PF12685.7 CDJ56206.1 - 0.49 10.2 10.5 0.77 9.5 10.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CCDC53 PF10152.9 CDJ56206.1 - 0.66 10.4 8.1 0.19 12.1 2.4 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Rad54_N PF08658.10 CDJ56206.1 - 0.73 10.0 10.8 0.073 13.2 1.8 2.3 2 0 0 2 2 2 0 Rad54 N terminal Coilin_N PF15862.5 CDJ56206.1 - 0.81 9.5 13.8 0.11 12.4 1.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 CDJ56206.1 - 1.3 7.7 9.3 2 7.1 9.3 1.3 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 CDJ56206.1 - 2.6 8.5 8.9 3.7 8.0 2.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 MMU163 PF17119.5 CDJ56206.1 - 5.8 6.0 7.2 0.4 9.8 1.5 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis SUIM_assoc PF16619.5 CDJ56208.1 - 8.7e-05 22.5 3.1 8.7e-05 22.5 3.1 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ56208.1 - 0.034 14.2 19.7 0.042 13.8 19.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 CDJ56208.1 - 0.058 13.4 14.3 0.085 12.9 14.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Hid1 PF12722.7 CDJ56208.1 - 0.41 8.7 2.1 0.48 8.5 2.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.14 CDJ56208.1 - 4.3 7.2 11.4 6 6.8 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 CDJ56209.1 - 0.00019 21.8 0.3 0.00019 21.8 0.3 14.7 3 3 5 10 10 10 2 Anti-sigma-K factor rskA Med15 PF09606.10 CDJ56209.1 - 0.0005 18.9 6.4 0.0005 18.9 6.4 6.5 5 2 0 6 6 6 2 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.9 CDJ56209.1 - 0.0055 16.8 1.4 0.0055 16.8 1.4 12.4 7 3 3 11 11 11 1 Cyclin-dependent kinase 2-associated protein Acyltransferase PF01553.21 CDJ56210.1 - 1.3e-18 66.9 0.0 1.7e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Topoisom_I PF01028.20 CDJ56211.1 - 1e-97 325.9 6.4 2.9e-97 324.5 6.4 1.7 1 1 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CDJ56211.1 - 7.6e-28 97.5 2.2 1.2e-23 83.8 0.0 4.1 4 0 0 4 4 4 2 Eukaryotic DNA topoisomerase I, DNA binding fragment MelC1 PF06236.11 CDJ56211.1 - 0.0077 16.3 0.9 0.0077 16.3 0.9 6.2 3 2 2 5 5 5 1 Tyrosinase co-factor MelC1 PPP4R2 PF09184.11 CDJ56211.1 - 2.3 7.7 14.5 0.51 9.9 7.9 2.3 2 0 0 2 2 2 0 PPP4R2 DUF3246 PF11596.8 CDJ56211.1 - 4.4 6.7 15.2 0.34 10.3 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Ssl1 PF04056.14 CDJ56212.1 - 4.3e-10 39.7 0.0 1.7e-09 37.8 0.0 2.0 2 1 0 3 3 3 1 Ssl1-like VWA_2 PF13519.6 CDJ56212.1 - 1.8e-06 28.6 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDJ56212.1 - 0.0063 16.8 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Slu7 PF11708.8 CDJ56213.1 - 3.5e-29 102.4 23.3 4.9e-25 88.8 2.3 3.5 2 1 2 4 4 4 2 Pre-mRNA splicing Prp18-interacting factor RskA PF10099.9 CDJ56213.1 - 0.0014 19.0 15.1 0.89 9.8 0.0 2.6 1 1 1 2 2 2 2 Anti-sigma-K factor rskA K_channel_TID PF07941.11 CDJ56213.1 - 0.019 15.4 12.3 0.019 15.4 12.3 4.5 3 2 1 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 CDJ56213.1 - 0.54 10.2 37.3 0.045 13.7 32.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 CDJ56213.1 - 1.7 9.1 12.3 0.64 10.4 7.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spt20 PF12090.8 CDJ56214.1 - 0.0062 16.2 10.4 0.0062 16.2 10.4 8.0 3 2 4 7 7 7 1 Spt20 family EI24 PF07264.11 CDJ56214.1 - 0.011 15.9 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2371 PF10177.9 CDJ56214.1 - 0.13 12.4 0.0 0.13 12.4 0.0 5.8 6 2 1 7 7 7 0 Uncharacterised conserved protein (DUF2371) SARAF PF06682.12 CDJ56215.1 - 0.00096 18.9 18.0 0.0015 18.2 18.0 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3619 PF12279.8 CDJ56215.1 - 0.021 15.1 2.2 0.021 15.1 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) GramPos_pilinD1 PF16555.5 CDJ56215.1 - 0.049 13.8 4.2 0.067 13.4 4.2 1.3 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF1345 PF07077.11 CDJ56215.1 - 0.54 9.9 1.6 0.54 9.9 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4175 PF13779.6 CDJ56215.1 - 0.96 7.3 34.6 1.2 7.0 34.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SPX PF03105.19 CDJ56215.1 - 2.1 8.2 22.7 8 6.3 22.7 1.7 1 1 0 1 1 1 0 SPX domain RAP1 PF07218.11 CDJ56215.1 - 5.3 5.2 8.3 5.8 5.1 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SpoIIE PF07228.12 CDJ56216.1 - 1.8e-09 37.8 0.2 2.5e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) RskA PF10099.9 CDJ56216.1 - 0.0073 16.6 11.3 0.0073 16.6 11.3 12.8 3 2 5 9 9 9 1 Anti-sigma-K factor rskA tRNA_synthFbeta PF17759.1 CDJ56217.1 - 3.3e-18 65.9 0.0 4.4e-12 45.9 0.0 2.5 1 1 1 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 CDJ56217.1 - 6e-13 48.9 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain Enolase_C PF00113.22 CDJ56218.1 - 7.3e-144 478.5 0.2 9.6e-144 478.1 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDJ56218.1 - 3.9e-58 195.3 0.1 7.8e-58 194.3 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDJ56218.1 - 2.3e-10 40.4 0.0 4.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDJ56218.1 - 7.7e-05 22.0 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Kri1 PF05178.12 CDJ56219.1 - 1.3e-16 61.0 14.2 1.3e-16 61.0 14.2 3.6 2 1 0 2 2 2 1 KRI1-like family TFIIA PF03153.13 CDJ56219.1 - 0.42 10.5 28.9 0.62 10.0 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF1_GNE PF00736.19 CDJ56220.1 - 1.9e-27 95.2 4.3 1.9e-27 95.2 4.3 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain DUF3381 PF11861.8 CDJ56220.1 - 0.021 14.6 16.7 0.072 12.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TRAP_alpha PF03896.16 CDJ56220.1 - 0.034 13.4 9.0 0.28 10.3 1.5 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ASC PF00858.24 CDJ56220.1 - 0.076 12.0 0.8 0.079 11.9 0.8 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel YlbD_coat PF14071.6 CDJ56220.1 - 0.31 11.3 14.4 0.092 13.0 5.8 2.2 2 0 0 2 2 2 0 Putative coat protein Cwf_Cwc_15 PF04889.12 CDJ56220.1 - 0.44 10.3 20.0 0.88 9.3 6.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LPD30 PF18850.1 CDJ56220.1 - 0.58 9.9 5.2 0.8 9.5 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 Connexin PF00029.19 CDJ56220.1 - 2.2 7.9 4.0 6.6 6.4 2.0 2.0 2 0 0 2 2 2 0 Connexin Pal1 PF08316.11 CDJ56220.1 - 2.6 8.8 7.1 0.8 10.5 2.2 2.0 2 0 0 2 2 2 0 Pal1 cell morphology protein Peptidase_S49_N PF08496.10 CDJ56220.1 - 3.4 7.7 9.3 5.1 7.2 4.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RPN2_C PF18004.1 CDJ56220.1 - 4 7.4 15.1 0.6 10.0 5.6 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain GEN1_C PF18380.1 CDJ56220.1 - 7.1 7.6 11.5 3.8 8.5 1.3 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF1207 PF06727.11 CDJ56221.1 - 0.034 13.1 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Collagen PF01391.18 CDJ56222.1 - 8.7e-19 67.0 103.2 1.3e-08 34.5 31.1 6.3 3 2 2 5 5 5 3 Collagen triple helix repeat (20 copies) KASH PF10541.9 CDJ56223.1 - 3 8.2 7.9 7.6 6.9 7.9 1.6 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF5320 PF17253.2 CDJ56224.1 - 0.0086 17.1 4.6 0.0086 17.1 4.6 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5320) DUF3459 PF11941.8 CDJ56224.1 - 4.8 7.6 7.2 1.1 9.6 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) TFIIA PF03153.13 CDJ56224.1 - 8 6.3 21.6 0.29 11.1 13.3 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Utp21 PF04192.12 CDJ56225.1 - 4.1e-12 46.1 1.1 5.5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain SR-25 PF10500.9 CDJ56225.1 - 0.0079 15.8 3.0 0.24 11.0 0.5 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ56226.1 - 0.006 15.6 3.0 0.006 15.6 3.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Hexapep PF00132.24 CDJ56226.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Spt20 PF12090.8 CDJ56226.1 - 1.3 8.5 18.2 0.058 13.0 12.2 1.7 2 0 0 2 2 2 0 Spt20 family SpoIIIAH PF12685.7 CDJ56227.1 - 0.039 13.8 0.0 0.039 13.8 0.0 12.1 3 3 3 6 6 6 0 SpoIIIAH-like protein DUF755 PF05501.11 CDJ56228.1 - 0.00053 20.2 7.6 0.00053 20.2 7.6 12.8 11 3 1 12 12 12 2 Domain of unknown function (DUF755) Dehydrin PF00257.19 CDJ56228.1 - 0.01 16.4 5.5 0.01 16.4 5.5 12.2 7 5 2 10 10 10 0 Dehydrin FAM104 PF15434.6 CDJ56228.1 - 0.042 14.4 0.1 0.042 14.4 0.1 8.7 6 3 2 8 8 8 0 Family 104 zf-RanBP PF00641.18 CDJ56228.1 - 0.47 9.8 4.1 0.95 8.8 4.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Pkinase PF00069.25 CDJ56229.1 - 4.8e-07 29.4 8.8 0.00057 19.3 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain SUIM_assoc PF16619.5 CDJ56229.1 - 0.0011 19.0 4.2 0.0011 19.0 4.2 6.3 3 3 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 NAM-associated PF14303.6 CDJ56229.1 - 0.0089 16.8 10.1 0.0089 16.8 10.1 4.9 3 2 0 4 4 4 1 No apical meristem-associated C-terminal domain PPP4R2 PF09184.11 CDJ56229.1 - 7.4 6.1 35.2 0.016 14.8 10.5 2.3 1 1 0 2 2 2 0 PPP4R2 IMUP PF15761.5 CDJ56231.1 - 0.024 15.3 12.3 0.12 13.0 2.0 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ56231.1 - 0.94 9.8 12.8 1.4 9.3 2.8 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain EIIBC-GUT_N PF03612.14 CDJ56231.1 - 6.4 6.5 0.0 6.4 6.5 0.0 5.4 3 2 1 5 5 5 0 Sorbitol phosphotransferase enzyme II N-terminus SR-25 PF10500.9 CDJ56231.1 - 8.4 5.9 46.3 0.04 13.5 17.6 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein GAS2 PF02187.17 CDJ56231.1 - 9.6 6.4 9.6 1.6 8.9 2.7 3.4 2 2 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain TFIIF_alpha PF05793.12 CDJ56233.1 - 0.00031 19.5 63.5 0.00031 19.5 63.5 7.8 4 1 3 7 7 7 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RskA PF10099.9 CDJ56233.1 - 0.0063 16.8 16.2 0.0063 16.8 16.2 25.6 7 5 10 17 17 17 1 Anti-sigma-K factor rskA BLM10_mid PF16507.5 CDJ56235.1 - 1.2e-05 24.2 0.0 0.044 12.4 0.0 2.7 2 0 0 2 2 2 2 Proteasome-substrate-size regulator, mid region RskA PF10099.9 CDJ56235.1 - 5.2e-05 23.6 0.0 5.2e-05 23.6 0.0 9.0 4 2 3 7 7 4 2 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ56235.1 - 0.00011 22.2 1.3 0.00011 22.2 1.3 5.7 3 1 0 3 3 1 1 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ56235.1 - 0.00035 20.6 43.5 0.04 13.8 17.9 3.4 3 0 0 3 3 3 3 SPX domain Apt1 PF10351.9 CDJ56235.1 - 0.0086 15.0 34.5 0.0083 15.0 11.1 3.7 4 0 0 4 4 4 3 Golgi-body localisation protein domain DUF4834 PF16118.5 CDJ56235.1 - 0.0097 16.8 30.7 0.8 10.7 1.6 5.7 5 1 0 5 5 5 2 Domain of unknown function (DUF4834) PHD PF00628.29 CDJ56235.1 - 0.17 11.8 0.5 0.45 10.5 0.5 1.6 1 0 0 1 1 1 0 PHD-finger UPF0524 PF15823.5 CDJ56235.1 - 0.27 10.6 11.7 1.8 7.9 0.5 4.0 3 0 0 3 3 3 0 UPF0524 of C3orf70 eIF-3_zeta PF05091.12 CDJ56235.1 - 0.9 8.4 15.4 0.75 8.7 0.4 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S49_N PF08496.10 CDJ56235.1 - 0.93 9.6 8.6 2.5 8.1 0.7 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Folate_carrier PF01770.18 CDJ56235.1 - 0.93 8.2 4.8 34 3.0 0.2 3.5 3 0 0 3 3 3 0 Reduced folate carrier U1snRNP70_N PF12220.8 CDJ56235.1 - 4.7 7.9 11.1 52 4.6 3.7 3.6 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA PF00004.29 CDJ56236.1 - 2.1e-19 70.3 0.0 6.3e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CDJ56236.1 - 2.7e-13 50.3 0.0 8.9e-12 45.3 0.0 2.7 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 CDJ56236.1 - 1.2e-07 31.8 0.0 3.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CDJ56236.1 - 7.3e-06 25.1 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CDJ56236.1 - 0.00011 22.6 0.0 0.00011 22.6 0.0 2.7 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CDJ56236.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ56236.1 - 0.00063 19.5 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ56236.1 - 0.00068 19.9 0.7 0.019 15.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDJ56236.1 - 0.0015 18.6 0.0 0.0015 18.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CDJ56236.1 - 0.011 16.2 1.3 0.19 12.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ56236.1 - 0.019 14.9 0.4 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase VIT1 PF01988.19 CDJ56236.1 - 0.027 14.4 8.8 0.025 14.5 1.4 2.8 2 0 0 2 2 2 0 VIT family NACHT PF05729.12 CDJ56236.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.4 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CDJ56236.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CDJ56236.1 - 0.053 13.7 0.0 0.053 13.7 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CDJ56236.1 - 0.063 13.8 0.0 0.063 13.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CDJ56236.1 - 0.092 12.7 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 CDJ56236.1 - 0.55 10.7 0.0 0.55 10.7 0.0 3.2 3 0 0 3 3 2 0 ABC transporter GREB1 PF15782.5 CDJ56236.1 - 3.4 4.7 21.4 7.9 3.5 21.4 1.5 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 CDJ56236.1 - 5.6 6.9 26.1 0.06 13.3 16.1 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zip PF02535.22 CDJ56236.1 - 8.2 5.5 11.0 15 4.6 11.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Androgen_recep PF02166.16 CDJ56237.1 - 0.0025 16.7 6.7 0.0025 16.7 6.7 9.3 5 2 3 8 8 8 2 Androgen receptor PDEase_I PF00233.19 CDJ56238.1 - 2.2e-17 63.6 0.2 3.2e-17 63.1 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ56238.1 - 0.028 14.7 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 HD domain RNA_pol_Rpb1_5 PF04998.17 CDJ56241.1 - 1.6e-75 254.0 0.0 9e-75 251.5 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDJ56241.1 - 4.3e-56 189.7 0.1 4e-38 131.2 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 CDJ56241.1 - 5.4e-15 55.3 0.1 1.7e-14 53.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 CDJ56241.1 - 1.2e-14 54.5 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDJ56241.1 - 1.6e-13 50.7 0.1 3.4e-11 43.1 0.0 3.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 TFIIF_beta PF02270.15 CDJ56245.1 - 0.028 14.5 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Tex_N PF09371.10 CDJ56245.1 - 0.053 13.2 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain RPA_C PF08784.11 CDJ56245.1 - 0.096 13.4 0.1 0.25 12.0 0.1 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Ribosomal_L22 PF00237.19 CDJ56246.1 - 1.7e-05 25.0 0.1 3.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Myb_DNA-binding PF00249.31 CDJ56248.1 - 8.2e-05 22.7 0.2 0.00014 21.9 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CDJ56248.1 - 0.00016 21.8 0.7 0.00026 21.1 0.7 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 CDJ56248.1 - 0.00037 20.7 0.2 0.00061 20.0 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.25 CDJ56249.1 - 1.4e-08 34.4 0.0 8.5e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 CDJ56249.1 - 0.0015 17.9 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Apt1 PF10351.9 CDJ56249.1 - 0.12 11.2 0.6 0.18 10.6 0.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ56249.1 - 7 5.1 8.6 11 4.4 8.6 1.3 1 0 0 1 1 1 0 Macoilin family FATC PF02260.20 CDJ56250.1 - 9.7e-06 25.3 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FATC domain Macoilin PF09726.9 CDJ56250.1 - 0.018 13.6 3.7 0.023 13.3 3.7 1.0 1 0 0 1 1 1 0 Macoilin family ANAPC_CDC26 PF10471.9 CDJ56250.1 - 0.084 13.7 17.7 1.3 9.9 4.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FAM176 PF14851.6 CDJ56250.1 - 0.13 11.9 2.3 0.61 9.7 0.1 2.1 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 CDJ56250.1 - 0.38 10.7 15.3 0.48 10.4 15.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAGE PF01454.19 CDJ56250.1 - 0.49 10.1 6.8 7.5 6.2 6.9 2.0 1 1 0 1 1 1 0 MAGE family Presenilin PF01080.17 CDJ56250.1 - 0.74 8.5 6.2 0.89 8.2 6.2 1.1 1 0 0 1 1 1 0 Presenilin Dehydrin PF00257.19 CDJ56250.1 - 1.8 9.1 13.3 0.89 10.1 9.2 2.3 1 1 1 2 2 2 0 Dehydrin SUIM_assoc PF16619.5 CDJ56250.1 - 3.8 7.7 27.4 1.6 8.8 7.2 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Secretin_N_2 PF07655.13 CDJ56251.1 - 3.5 8.2 54.1 1.3 9.6 22.3 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain DUF2076 PF09849.9 CDJ56252.1 - 0.016 15.3 14.0 0.016 15.3 14.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RskA PF10099.9 CDJ56254.1 - 0.00034 20.9 26.4 0.0031 17.8 8.7 2.1 1 1 1 2 2 2 2 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.10 CDJ56254.1 - 0.95 9.2 15.8 22 4.8 15.8 2.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 CDJ56254.1 - 1.6 8.7 57.9 2.2 8.2 57.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_23 PF13384.6 CDJ56255.1 - 8.9e-05 22.2 0.1 0.00086 19.0 0.1 2.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CDJ56255.1 - 0.011 15.9 0.3 0.011 15.9 0.3 4.5 5 0 0 5 5 5 0 Helix-turn-helix domain HTH_17 PF12728.7 CDJ56255.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Utp14 PF04615.13 CDJ56256.1 - 0.00053 18.7 21.1 0.00053 18.7 21.1 2.0 2 0 0 2 2 2 1 Utp14 protein Exo_endo_phos PF03372.23 CDJ56256.1 - 0.072 12.6 0.7 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Lin-8 PF03353.15 CDJ56256.1 - 0.6 9.6 30.1 1.2 8.6 26.1 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PCEMA1 PF07418.11 CDJ56256.1 - 9.1 5.7 12.3 20 4.6 12.3 1.6 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Kinesin PF00225.23 CDJ56258.1 - 1.5e-86 290.3 5.2 2.2e-43 148.5 0.0 3.1 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ56258.1 - 1.6e-20 73.6 0.3 9.8e-20 71.0 0.3 2.4 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ56258.1 - 7e-06 26.4 4.3 0.0005 20.5 0.0 3.6 3 0 0 3 3 3 2 Kinesin protein 1B FHA PF00498.26 CDJ56258.1 - 0.0006 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinesin_assoc PF16183.5 CDJ56258.1 - 0.0027 17.9 1.3 0.0027 17.9 1.3 4.1 3 1 1 4 4 4 1 Kinesin-associated DUF2015 PF09435.10 CDJ56258.1 - 0.067 13.0 1.2 0.18 11.7 1.2 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Exonuc_VII_L PF02601.15 CDJ56258.1 - 5.2 6.5 20.2 1.9 8.0 9.8 2.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit ATC_hydrolase PF14196.6 CDJ56258.1 - 6.2 7.6 7.1 11 6.8 0.4 2.8 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Ion_trans PF00520.31 CDJ56259.1 - 2.3e-58 197.3 83.6 1.3e-17 63.9 9.1 4.2 4 0 0 4 4 4 4 Ion transport protein ANAPC4_WD40 PF12894.7 CDJ56260.1 - 0.0026 18.0 0.0 0.054 13.8 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ56260.1 - 0.19 12.7 4.8 2.9 8.9 1.3 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat SR-25 PF10500.9 CDJ56261.1 - 1.7 8.2 28.1 0.022 14.4 14.6 2.1 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMYLE_N PF18615.1 CDJ56261.1 - 7.7 6.0 28.6 10 5.5 28.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SART-1 PF03343.13 CDJ56261.1 - 8.9 4.7 37.1 10 4.5 37.1 1.0 1 0 0 1 1 1 0 SART-1 family DUF3824 PF12868.7 CDJ56262.1 - 0.013 16.1 4.0 0.013 16.1 4.0 8.2 7 3 1 8 8 8 0 Domain of unknwon function (DUF3824) PPI_Ypi1 PF07491.11 CDJ56264.1 - 3.3e-22 78.1 0.1 5.6e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor Caskin1-CID PF16600.5 CDJ56264.1 - 0.012 16.1 2.0 0.023 15.3 2.0 1.5 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Med3 PF11593.8 CDJ56264.1 - 7.3 5.7 6.6 8.9 5.4 6.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 CDJ56265.1 - 4e-15 55.9 0.0 7.3e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ56265.1 - 1.3e-09 37.8 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ56265.1 - 2e-07 30.6 0.0 3.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ56265.1 - 0.1 12.5 0.7 0.41 10.5 0.1 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDJ56266.1 - 1.1e-14 54.5 0.0 2.1e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ56266.1 - 4.4e-13 49.2 0.0 7.9e-13 48.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ56266.1 - 5e-07 29.3 0.0 8.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ56266.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.7 CDJ56267.1 - 9.6e-13 49.2 0.0 2.8e-11 44.4 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ56267.1 - 1.2e-06 28.4 0.0 0.00032 20.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDJ56267.1 - 0.026 13.8 0.1 6 6.1 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 CDJ56267.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF5327 PF17261.2 CDJ56267.1 - 0.18 12.5 7.8 1.6 9.6 8.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) TFIIA PF03153.13 CDJ56267.1 - 0.3 11.0 13.4 0.088 12.8 10.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ56269.1 - 0.0094 16.0 6.3 0.0094 16.0 6.3 4.9 4 1 1 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2076) Snf7 PF03357.21 CDJ56270.1 - 1.3e-06 28.1 4.0 1.3e-06 28.1 4.0 1.9 2 0 0 2 2 2 1 Snf7 tRNA-synt_1c PF00749.21 CDJ56270.1 - 0.024 13.5 0.6 0.034 13.1 0.3 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Cdh1_DBD_1 PF18196.1 CDJ56270.1 - 0.51 10.7 6.1 0.22 11.9 3.2 1.9 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 TMEM43 PF07787.12 CDJ56271.1 - 8.9e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 DotU PF09850.9 CDJ56272.1 - 0.11 12.2 1.7 0.1 12.3 0.4 1.7 2 0 0 2 2 2 0 Type VI secretion system protein DotU Myc_target_1 PF15179.6 CDJ56273.1 - 0.0062 16.5 1.9 0.013 15.4 1.9 1.6 1 0 0 1 1 1 1 Myc target protein 1 DUF456 PF04306.13 CDJ56273.1 - 0.015 15.6 0.8 0.032 14.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) EGF PF00008.27 CDJ56273.1 - 0.057 13.7 2.6 0.098 13.0 2.6 1.4 1 0 0 1 1 1 0 EGF-like domain LRR19-TM PF15176.6 CDJ56273.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TMEM51 PF15345.6 CDJ56273.1 - 0.49 10.2 4.9 2.1 8.2 4.9 2.0 1 1 0 1 1 1 0 Transmembrane protein 51 Ank_2 PF12796.7 CDJ56274.1 - 7.7e-20 71.3 2.0 5.6e-05 23.7 0.5 4.4 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ56274.1 - 1.2e-15 57.2 7.1 0.00046 20.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDJ56274.1 - 9.4e-12 44.9 0.2 0.0015 18.8 0.0 5.6 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ56274.1 - 2.1e-11 43.0 6.1 0.031 14.8 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 CDJ56274.1 - 2.4e-11 43.9 0.2 0.11 13.1 0.0 6.1 3 3 2 5 5 5 5 Ankyrin repeats (many copies) Patched PF02460.18 CDJ56275.1 - 5.3e-50 170.4 3.4 6.6e-50 170.0 3.4 1.1 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 CDJ56275.1 - 4.3e-07 28.0 11.0 5.9e-07 27.6 11.0 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family T2SSM PF04612.12 CDJ56275.1 - 0.0079 16.3 1.1 0.019 15.0 1.1 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF2852 PF11014.8 CDJ56275.1 - 0.19 11.9 0.4 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) FlxA PF14282.6 CDJ56275.1 - 0.46 10.5 6.4 0.8 9.7 6.4 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4525 PF15027.6 CDJ56275.1 - 2 8.1 7.3 0.078 12.7 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) SecD_SecF PF02355.16 CDJ56275.1 - 7 6.0 16.3 0.037 13.4 5.3 2.1 2 0 0 2 2 2 0 Protein export membrane protein MMR1 PF08505.10 CDJ56277.1 - 0.068 13.5 22.5 0.14 12.4 22.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF5349 PF17298.2 CDJ56277.1 - 0.07 12.9 16.5 0.11 12.3 16.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF4179 PF13786.6 CDJ56277.1 - 3.6 8.1 11.0 93 3.6 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) Serglycin PF04360.12 CDJ56278.1 - 2.4e-05 24.3 1.5 2.4e-05 24.3 1.5 1.1 1 0 0 1 1 1 1 Serglycin AF-4 PF05110.13 CDJ56278.1 - 0.12 10.5 0.7 0.095 10.8 0.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AP2 PF00847.20 CDJ56279.1 - 3.5e-13 49.6 0.7 8.5e-10 38.7 0.0 5.4 6 0 0 6 6 6 2 AP2 domain DUF3420 PF11900.8 CDJ56281.1 - 0.26 11.4 0.3 0.26 11.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) MCM PF00493.23 CDJ56282.1 - 4.5e-93 310.5 0.1 8e-93 309.6 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ56282.1 - 2.6e-26 91.9 0.0 7.3e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CDJ56282.1 - 2.9e-26 91.7 2.6 5.5e-26 90.8 2.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ56282.1 - 9.5e-07 28.4 0.1 5.5e-06 25.9 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ56282.1 - 0.0034 17.3 0.0 0.0084 16.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ56282.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDJ56282.1 - 0.021 15.0 0.6 0.055 13.7 0.6 1.7 1 0 0 1 1 1 0 Midasin AAA lid domain Pox_mRNA-cap PF03341.13 CDJ56286.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit Bap31_Bap29_C PF18035.1 CDJ56286.1 - 0.31 11.1 3.1 0.92 9.6 3.1 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ribosomal_L14 PF00238.19 CDJ56287.1 - 3.9e-33 114.1 0.0 4.7e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PARG_cat PF05028.14 CDJ56288.1 - 2.7e-25 89.4 0.0 3.1e-10 39.9 0.0 4.1 4 0 0 4 4 4 3 Poly (ADP-ribose) glycohydrolase (PARG) FAM176 PF14851.6 CDJ56289.1 - 0.00054 19.6 3.1 0.00068 19.3 3.1 1.2 1 0 0 1 1 1 1 FAM176 family FTZ PF03867.14 CDJ56289.1 - 0.014 14.9 6.5 0.017 14.7 6.5 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Mitofilin PF09731.9 CDJ56289.1 - 0.017 14.0 11.0 0.018 13.9 11.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spt20 PF12090.8 CDJ56289.1 - 0.021 14.5 17.6 0.023 14.3 17.6 1.1 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 CDJ56289.1 - 0.041 14.3 4.5 0.046 14.1 4.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like SKA1 PF07160.12 CDJ56289.1 - 0.095 12.5 5.4 0.11 12.3 5.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CCDC106 PF15794.5 CDJ56289.1 - 0.18 11.5 10.9 0.22 11.2 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2722 PF10846.8 CDJ56289.1 - 0.22 10.4 14.5 0.28 10.1 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Borrelia_P83 PF05262.11 CDJ56289.1 - 0.43 9.0 12.4 0.47 8.9 12.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 CDJ56289.1 - 0.44 9.3 9.1 0.48 9.1 9.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TraV PF09676.10 CDJ56289.1 - 0.59 11.1 10.7 0.73 10.8 10.7 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FAM60A PF15396.6 CDJ56289.1 - 0.66 9.9 6.7 0.75 9.8 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.9 CDJ56289.1 - 0.92 8.0 9.1 1.1 7.8 9.1 1.0 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 CDJ56289.1 - 1 9.4 4.4 1.1 9.3 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 CDJ56289.1 - 1.1 8.6 12.6 1.4 8.3 12.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 CDJ56289.1 - 1.2 7.8 10.5 1.3 7.7 10.5 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ56289.1 - 1.3 7.0 7.5 1.4 7.0 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gti1_Pac2 PF09729.9 CDJ56289.1 - 1.4 8.9 7.5 1.8 8.7 7.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Sec62 PF03839.16 CDJ56289.1 - 1.5 8.3 8.2 1.8 8.0 8.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CDJ56289.1 - 1.9 7.2 7.3 2 7.1 7.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CDJ56289.1 - 2 7.4 7.7 2.1 7.3 7.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 CDJ56289.1 - 2 7.0 8.8 2.1 6.9 8.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ56289.1 - 2.7 6.7 5.5 2.9 6.6 5.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Herpes_DNAp_acc PF04929.12 CDJ56289.1 - 3.1 6.7 8.3 3.6 6.5 8.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GREB1 PF15782.5 CDJ56289.1 - 5.5 4.0 8.9 5.9 3.9 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ56289.1 - 6.1 6.0 4.4 6.8 5.8 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CDJ56289.1 - 7 5.5 8.7 8 5.3 8.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3499 PF12005.8 CDJ56289.1 - 8.8 7.0 9.4 24 5.5 9.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) Suf PF05843.14 CDJ56289.1 - 9.9 6.0 11.6 12 5.7 11.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.19 CDJ56290.1 - 0.0076 16.8 12.5 0.0076 16.8 12.5 10.4 5 3 2 7 7 7 2 60s Acidic ribosomal protein DUF4238 PF14022.6 CDJ56290.1 - 1.3 8.4 12.8 0.093 12.2 6.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) Hamartin PF04388.12 CDJ56291.1 - 4.3 5.9 37.2 0.65 8.6 13.1 2.3 2 0 0 2 2 2 0 Hamartin protein DUF192 PF02643.15 CDJ56292.1 - 0.063 13.4 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Ribosomal_L22 PF00237.19 CDJ56292.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e rve PF00665.26 CDJ56293.1 - 6.3e-18 65.1 0.3 3.5e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CDJ56293.1 - 3.9e-17 62.1 0.6 1.3e-16 60.5 0.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDJ56293.1 - 2.7e-14 53.3 1.1 6.6e-14 52.1 1.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ56293.1 - 3.3e-12 46.1 0.0 6.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDJ56293.1 - 1.5e-05 25.0 0.1 3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 CDJ56293.1 - 0.0035 17.1 2.6 0.0042 16.8 0.2 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDJ56293.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.4 2 0 0 2 2 2 0 H2C2 zinc finger NIF PF03031.18 CDJ56294.1 - 4.7e-18 65.4 0.0 2.7e-06 27.3 0.0 4.5 3 1 1 4 4 4 2 NLI interacting factor-like phosphatase RskA PF10099.9 CDJ56294.1 - 1.2e-06 28.9 29.3 7.2e-06 26.4 9.1 18.2 5 3 10 15 15 15 3 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.18 CDJ56294.1 - 0.0011 18.7 4.8 0.4 10.4 0.5 5.2 4 2 0 4 4 4 1 DNA methylase Collagen_mid PF15984.5 CDJ56294.1 - 0.0062 16.3 5.6 0.0062 16.3 5.6 2.3 3 0 0 3 3 3 1 Bacterial collagen, middle region EMP24_GP25L PF01105.24 CDJ56295.1 - 4.9e-16 59.2 0.0 8.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TFIIA PF03153.13 CDJ56295.1 - 0.49 10.3 68.2 0.83 9.6 68.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ56295.1 - 1.2 7.9 7.6 0.37 9.6 4.5 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ56295.1 - 6.1 5.0 7.3 11 4.2 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosom_S12_S23 PF00164.25 CDJ56296.1 - 3.9e-51 171.4 0.3 5.1e-51 171.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 CDJ56296.1 - 0.013 15.0 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AP2 PF00847.20 CDJ56298.1 - 1.1e-20 73.5 3.9 1.4e-12 47.6 0.7 4.9 4 0 0 4 4 4 2 AP2 domain Phage_holin_3_6 PF07332.11 CDJ56299.1 - 0.15 12.1 5.7 0.44 10.6 5.7 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III FA_desaturase PF00487.24 CDJ56299.1 - 0.24 11.2 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.9 CDJ56299.1 - 0.27 10.0 2.6 1.1 7.9 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PP2C PF00481.21 CDJ56300.1 - 2e-39 135.8 3.4 2.5e-39 135.5 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ56300.1 - 8.8e-05 22.2 0.0 8.8e-05 22.2 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C Thioredoxin PF00085.20 CDJ56301.1 - 3.6e-56 187.5 0.6 1.9e-31 108.1 0.3 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ56301.1 - 2.1e-10 40.8 0.0 0.00038 20.4 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ56301.1 - 4.7e-10 39.3 0.0 6.9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDJ56301.1 - 6.1e-08 32.6 0.2 0.019 15.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.6 CDJ56301.1 - 1e-07 32.0 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CDJ56301.1 - 1.7e-07 31.5 0.1 0.11 12.8 0.0 4.0 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CDJ56301.1 - 4e-06 26.9 0.4 0.07 13.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CDJ56301.1 - 4e-05 23.5 0.2 0.088 12.7 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 CDJ56301.1 - 4.5e-05 23.2 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CDJ56301.1 - 8.8e-05 22.9 4.7 0.99 9.9 0.4 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CDJ56301.1 - 0.044 13.9 1.5 14 5.8 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin LUC7 PF03194.15 CDJ56302.1 - 3.5e-27 95.7 0.5 1.2e-18 67.8 0.0 3.8 3 1 1 4 4 4 2 LUC7 N_terminus DUF4080 PF13311.6 CDJ56302.1 - 0.21 11.8 3.7 0.36 11.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Adap_comp_sub PF00928.21 CDJ56303.1 - 2.8e-12 46.6 0.0 1.2e-09 38.0 0.0 2.0 1 1 1 2 2 2 2 Adaptor complexes medium subunit family HOOK PF05622.12 CDJ56304.1 - 1.1e-07 30.5 81.3 2.3e-07 29.4 79.2 2.2 1 1 0 1 1 1 1 HOOK protein FlxA PF14282.6 CDJ56304.1 - 0.014 15.3 8.7 0.014 15.3 8.7 11.5 3 2 6 10 10 10 0 FlxA-like protein WD40_alt PF14077.6 CDJ56304.1 - 0.17 11.7 3.0 2.9 7.8 2.3 3.5 2 1 1 3 3 3 0 Alternative WD40 repeat motif Nse4_C PF08743.10 CDJ56305.1 - 9.7e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Secretin_N_2 PF07655.13 CDJ56305.1 - 0.01 16.4 1.4 0.01 16.4 1.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Aminotran_5 PF00266.19 CDJ56306.1 - 3e-81 273.2 0.0 1.1e-80 271.3 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDJ56306.1 - 5.1e-10 39.1 0.0 1e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II SUIM_assoc PF16619.5 CDJ56306.1 - 0.0037 17.3 5.7 0.005 16.9 0.8 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Met_gamma_lyase PF06838.11 CDJ56306.1 - 0.016 13.8 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Lipase_GDSL_2 PF13472.6 CDJ56306.1 - 0.089 13.2 0.3 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SelA PF03841.13 CDJ56306.1 - 0.16 10.9 0.1 0.5 9.3 0.0 1.7 1 1 1 2 2 2 0 L-seryl-tRNA selenium transferase Spt20 PF12090.8 CDJ56306.1 - 0.3 10.7 4.6 0.59 9.7 4.6 1.4 1 0 0 1 1 1 0 Spt20 family NUDIX PF00293.28 CDJ56307.1 - 4.7e-15 55.8 0.0 7.8e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain AAA_12 PF13087.6 CDJ56309.1 - 7e-30 104.1 0.0 7e-30 104.1 0.0 4.1 3 1 0 3 3 3 1 AAA domain TFIIA PF03153.13 CDJ56310.1 - 0.0079 16.2 14.4 0.0092 16.0 14.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPARC_Ca_bdg PF10591.9 CDJ56310.1 - 0.017 15.4 4.3 0.017 15.4 4.3 1.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DDE_Tnp_IS1595 PF12762.7 CDJ56310.1 - 0.032 14.2 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain FHIPEP PF00771.20 CDJ56310.1 - 0.15 10.5 3.2 0.16 10.4 3.2 1.1 1 0 0 1 1 1 0 FHIPEP family Pro_CA PF00484.19 CDJ56310.1 - 0.85 9.9 5.9 1.3 9.3 5.9 1.2 1 0 0 1 1 1 0 Carbonic anhydrase LsmAD PF06741.13 CDJ56310.1 - 1.1 9.9 3.8 6.4 7.4 2.3 2.1 2 0 0 2 2 2 0 LsmAD domain Peptidase_S46 PF10459.9 CDJ56310.1 - 1.6 7.3 7.7 1.9 7.1 7.7 1.0 1 0 0 1 1 1 0 Peptidase S46 TBCC_N PF16752.5 CDJ56310.1 - 2.8 8.4 16.5 7.3 7.1 16.5 1.6 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Presenilin PF01080.17 CDJ56310.1 - 2.8 6.6 5.2 3.6 6.3 5.2 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.18 CDJ56312.1 - 0.0024 17.5 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Pap_E4 PF02711.14 CDJ56314.1 - 0.036 15.0 0.5 0.056 14.4 0.5 1.4 1 0 0 1 1 1 0 E4 protein BUD22 PF09073.10 CDJ56314.1 - 0.079 12.3 26.6 0.1 11.9 26.6 1.1 1 0 0 1 1 1 0 BUD22 Plasmodium_Vir PF05795.11 CDJ56314.1 - 2.1 7.7 6.9 2.3 7.6 6.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ERM PF00769.19 CDJ56314.1 - 2.7 7.8 25.4 3.4 7.4 25.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TAF8_C PF10406.9 CDJ56317.1 - 1.6e-06 28.6 1.1 1.6e-06 28.6 1.1 3.4 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term SR-25 PF10500.9 CDJ56317.1 - 2.7e-05 23.9 4.0 2.7e-05 23.9 4.0 3.4 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ56317.1 - 0.00095 19.5 0.1 0.00095 19.5 0.1 4.3 1 1 2 3 3 3 1 Anti-sigma-K factor rskA ATG27 PF09451.10 CDJ56317.1 - 1.4 8.7 6.4 0.052 13.4 0.6 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 CCSAP PF15748.5 CDJ56317.1 - 3.8 7.6 36.1 0.65 10.1 8.3 3.2 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated RskA PF10099.9 CDJ56318.1 - 0.0048 17.2 11.1 0.0048 17.2 11.1 4.7 1 1 2 3 3 3 1 Anti-sigma-K factor rskA AlbA_2 PF04326.14 CDJ56318.1 - 0.055 13.8 2.1 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain Utp14 PF04615.13 CDJ56318.1 - 0.75 8.3 41.5 0.95 8.0 41.5 1.2 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 CDJ56318.1 - 2.2 8.2 84.7 0.91 9.5 37.6 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit APG6_N PF17675.1 CDJ56319.1 - 0.00058 20.4 9.0 0.00058 20.4 9.0 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region Hemagglutinin PF00509.18 CDJ56319.1 - 0.017 13.5 1.1 0.024 13.1 1.1 1.1 1 0 0 1 1 1 0 Haemagglutinin Macoilin PF09726.9 CDJ56319.1 - 0.017 13.7 15.6 0.022 13.3 15.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF4446 PF14584.6 CDJ56319.1 - 0.02 14.9 0.3 0.02 14.9 0.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) HlyD_2 PF12700.7 CDJ56319.1 - 0.053 12.3 0.4 0.076 11.7 0.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein JIP_LZII PF16471.5 CDJ56319.1 - 0.24 11.6 11.3 0.66 10.2 11.1 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II SPX PF03105.19 CDJ56319.1 - 0.37 10.7 7.2 0.52 10.2 7.2 1.2 1 0 0 1 1 1 0 SPX domain Tmemb_cc2 PF10267.9 CDJ56319.1 - 0.75 8.9 15.9 1.7 7.7 15.9 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1977 PF09320.11 CDJ56319.1 - 4.8 7.5 7.6 0.53 10.6 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1977) YabA PF06156.13 CDJ56319.1 - 5.5 7.7 9.5 0.38 11.4 3.5 2.0 2 0 0 2 2 2 0 Initiation control protein YabA LidA_Long_CC PF18641.1 CDJ56319.1 - 9.7 6.2 17.0 0.35 10.9 4.6 2.3 2 0 0 2 2 2 0 LidA long coiled-coil domain IMP2_N PF18590.1 CDJ56320.1 - 1.5e-12 47.9 0.5 5.8e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 Immune Mapped Protein 2 (IMP2) N-terminal domain Pex14_N PF04695.13 CDJ56320.1 - 0.42 11.3 4.4 0.58 10.8 4.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.9 CDJ56321.1 - 0.00065 19.9 5.1 0.00065 19.9 5.1 1.7 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 CDJ56321.1 - 0.002 18.1 0.6 0.002 18.1 0.6 2.2 2 0 0 2 2 2 1 Myc amino-terminal region FYDLN_acid PF09538.10 CDJ56321.1 - 0.007 17.0 3.7 0.007 17.0 3.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (FYDLN_acid) FHIPEP PF00771.20 CDJ56321.1 - 0.061 11.8 0.0 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 FHIPEP family CENP-B_dimeris PF09026.10 CDJ56321.1 - 0.14 12.6 10.3 0.25 11.7 10.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Shadoo PF14999.6 CDJ56321.1 - 0.75 9.9 19.1 0.16 12.0 0.2 2.9 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective RPN2_C PF18004.1 CDJ56321.1 - 0.98 9.3 8.4 2.3 8.1 8.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 CDJ56321.1 - 2.3 6.2 15.9 3.4 5.7 15.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CDJ56321.1 - 2.5 6.3 10.8 4.3 5.5 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 CDJ56321.1 - 2.5 7.8 12.8 0.042 13.6 5.4 1.8 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.12 CDJ56321.1 - 3.3 5.8 15.0 4.9 5.2 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 CDJ56321.1 - 4 6.6 11.0 0.3 10.2 6.0 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 CDJ56321.1 - 5.9 5.7 7.8 0.75 8.7 1.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 CDJ56321.1 - 7.1 6.3 13.7 1.6 8.4 9.9 1.8 2 0 0 2 2 2 0 FAM176 family Nop53 PF07767.11 CDJ56321.1 - 8.7 5.6 19.3 0.84 9.0 14.8 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF4746 PF15928.5 CDJ56321.1 - 8.8 5.7 16.1 2.1 7.7 13.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 CDJ56321.1 - 10 5.4 15.5 17 4.6 15.5 1.3 1 0 0 1 1 1 0 NOA36 protein YceD PF02620.17 CDJ56322.1 - 0.24 11.5 9.5 0.37 10.9 6.9 2.1 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD DUF5585 PF17823.1 CDJ56322.1 - 0.3 10.0 31.3 0.44 9.5 31.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) SUIM_assoc PF16619.5 CDJ56322.1 - 0.31 11.1 29.0 0.06 13.4 1.6 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 NAC PF01849.18 CDJ56323.1 - 1.2e-13 50.8 0.0 2.1e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NAC domain Thioredoxin_6 PF13848.6 CDJ56324.1 - 5.9e-06 26.3 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Ribosomal_60s PF00428.19 CDJ56324.1 - 0.0002 21.9 2.5 0.0002 21.9 2.5 5.6 3 1 0 3 3 3 1 60s Acidic ribosomal protein Thioredoxin PF00085.20 CDJ56324.1 - 0.0005 20.0 0.0 0.0037 17.2 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin TRAPPC-Trs85 PF12739.7 CDJ56325.1 - 1.2e-32 113.4 0.5 1.2e-32 113.4 0.5 4.2 4 2 0 4 4 4 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2722 PF10846.8 CDJ56325.1 - 0.0018 17.3 6.9 0.0018 17.3 6.9 7.6 5 2 1 6 6 6 1 Protein of unknown function (DUF2722) DUF2207 PF09972.9 CDJ56325.1 - 0.01 14.6 0.1 0.18 10.5 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ICE2 PF08426.10 CDJ56325.1 - 1.5 7.8 4.1 5.8 5.9 0.5 2.3 2 0 0 2 2 2 0 ICE2 SPX PF03105.19 CDJ56327.1 - 0.0021 18.0 25.8 0.0021 18.0 25.8 8.4 4 3 1 5 5 5 2 SPX domain RskA PF10099.9 CDJ56327.1 - 0.024 14.9 0.0 0.024 14.9 0.0 14.4 3 3 7 10 10 10 0 Anti-sigma-K factor rskA NAM-associated PF14303.6 CDJ56327.1 - 0.26 12.0 0.0 0.26 12.0 0.0 11.7 8 4 1 10 10 10 0 No apical meristem-associated C-terminal domain Cellulose_synt PF03552.14 CDJ56328.1 - 0.0057 15.2 4.1 0.0065 15.0 4.1 1.1 1 0 0 1 1 1 1 Cellulose synthase Hid1 PF12722.7 CDJ56328.1 - 0.0072 14.5 0.0 0.0072 14.5 0.0 3.0 1 1 2 3 3 2 2 High-temperature-induced dauer-formation protein NARP1 PF12569.8 CDJ56328.1 - 0.012 14.5 12.6 0.013 14.4 12.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 CDJ56328.1 - 0.014 14.1 20.9 0.018 13.8 20.9 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CDJ56328.1 - 0.02 13.7 13.4 0.027 13.3 13.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF966 PF06136.13 CDJ56328.1 - 0.03 14.0 10.7 0.032 13.9 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SART-1 PF03343.13 CDJ56328.1 - 0.037 12.6 31.9 0.045 12.3 31.9 1.0 1 0 0 1 1 1 0 SART-1 family Ureide_permease PF07168.11 CDJ56328.1 - 0.039 12.7 0.7 0.053 12.3 0.7 1.3 1 0 0 1 1 1 0 Ureide permease Ndc1_Nup PF09531.10 CDJ56328.1 - 0.073 11.8 11.0 0.077 11.7 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ56328.1 - 0.082 11.7 15.6 0.094 11.5 15.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 CDJ56328.1 - 0.22 10.9 9.4 0.27 10.6 9.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2151 PF10221.9 CDJ56328.1 - 0.36 9.4 10.4 0.41 9.2 10.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator V_ATPase_I PF01496.19 CDJ56328.1 - 0.38 8.6 18.1 0.49 8.3 18.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_41 PF13844.6 CDJ56328.1 - 0.43 9.0 4.7 0.52 8.7 4.7 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 FancD2 PF14631.6 CDJ56328.1 - 0.44 7.9 11.5 0.53 7.6 11.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CAF1 PF04857.20 CDJ56328.1 - 0.52 9.4 11.1 0.78 8.8 11.1 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease ALMT PF11744.8 CDJ56328.1 - 0.55 9.0 17.0 0.71 8.6 17.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Raftlin PF15250.6 CDJ56328.1 - 0.75 8.5 15.9 0.91 8.2 15.9 1.1 1 0 0 1 1 1 0 Raftlin HCO3_cotransp PF00955.21 CDJ56328.1 - 1.3 7.8 7.7 0.6 8.9 4.4 1.8 2 0 0 2 2 2 0 HCO3- transporter family DUF2370 PF10176.9 CDJ56328.1 - 1.5 8.4 6.2 2.4 7.8 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) GAGA_bind PF06217.12 CDJ56328.1 - 1.7 8.9 15.0 2.1 8.6 15.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CDJ56328.1 - 1.9 8.2 25.8 2.5 7.9 25.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.9 CDJ56328.1 - 2.4 6.1 10.6 3.1 5.8 10.6 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Rtf2 PF04641.12 CDJ56328.1 - 3.3 7.0 18.4 3.9 6.8 18.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.14 CDJ56328.1 - 3.4 5.8 23.5 4.2 5.6 23.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Smg8_Smg9 PF10220.9 CDJ56328.1 - 3.7 5.8 19.8 4.3 5.5 19.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 FAM60A PF15396.6 CDJ56328.1 - 3.7 7.5 17.1 4.9 7.1 17.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.6 CDJ56328.1 - 4 7.0 22.4 4.9 6.7 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Exonuc_VII_L PF02601.15 CDJ56328.1 - 4.2 6.9 21.4 5.3 6.5 21.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3292 PF11696.8 CDJ56328.1 - 4.4 5.5 17.1 5.3 5.3 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CLN3 PF02487.17 CDJ56328.1 - 6.4 5.7 14.4 9.2 5.2 14.4 1.3 1 0 0 1 1 1 0 CLN3 protein SAPS PF04499.15 CDJ56328.1 - 6.5 5.4 19.6 8.2 5.1 19.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Membralin PF09746.9 CDJ56328.1 - 7 5.6 13.1 9.8 5.1 13.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein Endostatin PF06482.11 CDJ56328.1 - 7.3 6.0 19.3 9.2 5.6 19.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCSAP PF15748.5 CDJ56328.1 - 7.3 6.7 28.4 9.7 6.3 28.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Otopetrin PF03189.13 CDJ56328.1 - 7.4 5.3 10.1 11 4.7 10.1 1.4 1 0 0 1 1 1 0 Otopetrin Gti1_Pac2 PF09729.9 CDJ56328.1 - 7.7 6.6 17.2 11 6.1 17.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 CDJ56328.1 - 8.6 5.3 25.0 11 5.0 25.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sof1 PF04158.14 CDJ56329.1 - 1.4e-27 95.7 12.0 2.1e-27 95.2 12.0 1.2 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CDJ56329.1 - 1e-09 38.8 0.1 0.0031 18.3 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56329.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDJ56329.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A EXOSC1 PF10447.9 CDJ56330.1 - 6.4e-09 36.4 0.0 1.3e-08 35.4 0.0 1.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CDJ56330.1 - 0.0055 16.5 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NAM-associated PF14303.6 CDJ56332.1 - 0.0019 19.0 0.0 0.0019 19.0 0.0 9.6 3 2 3 6 6 6 1 No apical meristem-associated C-terminal domain tRNA-synt_2d PF01409.20 CDJ56333.1 - 3e-07 30.2 0.0 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF3806 PF12713.7 CDJ56333.1 - 0.086 12.6 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) DUF755 PF05501.11 CDJ56335.1 - 0.015 15.5 18.1 0.015 15.5 18.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TFIIA PF03153.13 CDJ56335.1 - 0.018 15.0 11.2 0.027 14.5 11.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ56335.1 - 0.032 14.5 21.1 0.076 13.3 8.4 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain V_ATPase_I PF01496.19 CDJ56335.1 - 0.05 11.5 2.8 0.07 11.0 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF86 PF01934.17 CDJ56335.1 - 0.15 11.9 1.1 0.36 10.7 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF86 DUF4208 PF13907.6 CDJ56335.1 - 0.16 12.5 2.6 0.44 11.0 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Miga PF10265.9 CDJ56335.1 - 0.17 10.8 18.5 0.13 11.2 10.2 2.6 2 1 1 3 3 3 0 Mitoguardin Lys-AminoMut_A PF09043.11 CDJ56335.1 - 0.18 10.3 1.2 0.25 9.7 1.2 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit baeRF_family10 PF18854.1 CDJ56335.1 - 0.24 11.6 5.8 7.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 MCU PF04678.13 CDJ56335.1 - 0.32 11.1 3.8 0.44 10.6 2.8 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF572 PF04502.13 CDJ56335.1 - 0.63 9.6 6.5 1.1 8.8 6.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2064 PF09837.9 CDJ56335.1 - 0.82 9.5 6.5 0.11 12.3 0.6 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) RIC3 PF15361.6 CDJ56335.1 - 1.7 9.0 5.3 2.5 8.5 2.7 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 RskA PF10099.9 CDJ56335.1 - 8.6 6.6 22.6 2.2 8.5 0.2 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ56336.1 - 5.8e-39 134.0 10.9 1.2e-24 87.1 0.0 5.3 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56336.1 - 4.3e-12 45.9 14.5 8.6e-09 35.1 11.7 3.7 4 1 0 4 4 4 2 Protein tyrosine kinase DUF2076 PF09849.9 CDJ56336.1 - 0.00025 21.2 18.3 0.00025 21.2 18.3 7.7 5 2 2 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2076) GEMIN8 PF15348.6 CDJ56336.1 - 0.00059 20.2 13.9 0.00059 20.2 13.9 7.0 6 1 0 6 6 6 1 Gemini of Cajal bodies-associated protein 8 Auxin_canalis PF05703.11 CDJ56336.1 - 0.0059 16.6 20.6 0.0059 16.6 20.6 11.1 8 3 2 11 11 11 1 Auxin canalisation SR-25 PF10500.9 CDJ56336.1 - 0.006 16.2 6.0 0.006 16.2 6.0 10.7 9 2 0 9 9 9 2 Nuclear RNA-splicing-associated protein DUF5308 PF17233.2 CDJ56336.1 - 0.0077 16.5 2.8 0.0077 16.5 2.8 8.7 6 3 0 6 6 6 1 Family of unknown function (DUF5308) Afi1 PF07792.12 CDJ56336.1 - 0.027 15.0 0.7 0.027 15.0 0.7 7.4 7 2 1 8 8 8 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_ser-thr_kin PF05445.11 CDJ56336.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RskA PF10099.9 CDJ56336.1 - 0.44 10.8 0.0 0.44 10.8 0.0 12.7 3 3 6 9 9 9 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ56339.1 - 0.011 16.2 14.7 0.011 16.2 14.7 4.3 2 1 2 4 4 4 0 60s Acidic ribosomal protein HP0268 PF18618.1 CDJ56339.1 - 1.9 9.0 4.6 0.42 11.1 0.6 2.0 2 0 0 2 2 2 0 HP0268 RskA PF10099.9 CDJ56339.1 - 8.1 6.7 54.9 23 5.2 16.5 3.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA adh_short PF00106.25 CDJ56341.1 - 7.3e-14 51.7 7.6 1.6e-06 27.7 0.4 5.4 4 2 0 4 4 4 3 short chain dehydrogenase DUF1645 PF07816.11 CDJ56341.1 - 0.00079 20.1 0.6 0.00079 20.1 0.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1645) GDP_Man_Dehyd PF16363.5 CDJ56341.1 - 0.07 12.5 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Lin-8 PF03353.15 CDJ56341.1 - 0.1 12.1 3.9 0.041 13.5 1.4 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PHP PF02811.19 CDJ56341.1 - 0.11 12.8 0.6 0.34 11.2 0.6 1.8 1 1 0 1 1 1 0 PHP domain SUIM_assoc PF16619.5 CDJ56341.1 - 0.92 9.6 26.2 0.56 10.3 5.4 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HSP70 PF00012.20 CDJ56343.1 - 7.1e-19 67.4 0.1 2.8e-12 45.6 0.0 4.9 3 1 2 5 5 5 3 Hsp70 protein TFIIA PF03153.13 CDJ56343.1 - 0.0067 16.5 45.0 0.053 13.5 21.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit PMT2_N PF17987.1 CDJ56343.1 - 0.12 12.6 0.7 0.23 11.6 0.7 1.4 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DREPP PF05558.12 CDJ56343.1 - 2.2 8.1 17.8 0.35 10.7 7.5 2.8 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide RNase_H2_suC PF08615.11 CDJ56343.1 - 3.3 7.9 7.5 4.5 7.5 0.6 2.8 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) INSIG PF07281.12 CDJ56344.1 - 0.45 10.1 1.8 10 5.7 0.1 2.7 3 0 0 3 3 3 0 Insulin-induced protein (INSIG) FHIPEP PF00771.20 CDJ56344.1 - 0.92 7.9 9.0 0.12 10.9 2.4 2.0 2 0 0 2 2 2 0 FHIPEP family DUF572 PF04502.13 CDJ56344.1 - 2.6 7.6 15.7 4.6 6.8 15.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2967 PF11179.8 CDJ56346.1 - 3.5 5.6 8.6 4.5 5.3 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RXT2_N PF08595.11 CDJ56348.1 - 0.13 12.3 11.8 0.21 11.6 11.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal ICA69 PF04629.14 CDJ56348.1 - 0.36 11.1 11.3 0.45 10.8 11.3 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain D123 PF07065.14 CDJ56348.1 - 3 6.9 8.4 4.7 6.3 8.4 1.4 1 1 0 1 1 1 0 D123 WD40 PF00400.32 CDJ56349.1 - 2.3e-11 44.1 9.6 0.00069 20.4 0.0 4.4 3 1 1 4 4 4 4 WD domain, G-beta repeat Cadherin_tail PF15974.5 CDJ56349.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region DUF4329 PF14220.6 CDJ56350.1 - 0.085 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) DivIC PF04977.15 CDJ56350.1 - 0.84 9.5 5.4 2.6 7.9 5.4 1.8 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDJ56350.1 - 1.1 8.8 13.9 1.8 8.1 13.9 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ56350.1 - 1.4 9.1 14.0 3.4 7.8 14.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ56350.1 - 6.4 5.6 12.2 9.6 5.0 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ56350.1 - 8.1 5.4 6.4 15 4.5 6.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein EF-hand_8 PF13833.6 CDJ56351.1 - 5.9e-09 35.7 0.1 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ56351.1 - 5.2e-08 31.9 0.3 0.00084 18.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ56351.1 - 7.6e-07 28.6 0.7 0.0048 16.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ56351.1 - 1.8e-06 27.1 0.5 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ56351.1 - 4.7e-06 27.0 0.1 3.9e-05 24.0 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair FAM176 PF14851.6 CDJ56351.1 - 0.013 15.2 3.3 0.019 14.6 0.4 2.2 2 0 0 2 2 2 0 FAM176 family DUF4589 PF15252.6 CDJ56351.1 - 0.016 15.3 0.2 0.016 15.3 0.2 3.8 3 1 1 4 4 3 0 Domain of unknown function (DUF4589) PAXIP1_C PF15364.6 CDJ56351.1 - 0.016 15.5 1.6 0.016 15.5 1.6 2.5 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3464 PF11947.8 CDJ56351.1 - 0.022 14.5 7.9 0.3 10.8 3.2 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2052 PF09747.9 CDJ56351.1 - 0.054 13.6 6.9 0.28 11.3 5.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MAM33 PF02330.16 CDJ56351.1 - 0.16 11.9 8.9 0.91 9.4 4.4 2.4 2 0 0 2 2 2 0 Mitochondrial glycoprotein DUF3169 PF11368.8 CDJ56351.1 - 0.19 11.2 0.7 0.46 10.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) dsDNA_bind PF01984.20 CDJ56351.1 - 0.27 11.5 18.0 6.1 7.2 0.5 3.8 3 0 0 3 3 3 0 Double-stranded DNA-binding domain MPM1 PF17234.2 CDJ56351.1 - 0.38 11.0 7.4 2.3 8.4 4.3 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PGA2 PF07543.12 CDJ56351.1 - 0.51 10.3 8.4 0.45 10.5 2.6 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4207 PF13904.6 CDJ56351.1 - 0.59 9.8 17.9 0.062 13.0 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF4834 PF16118.5 CDJ56351.1 - 0.59 11.1 7.3 0.89 10.6 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDJ56351.1 - 1.2 8.2 12.3 0.026 13.6 0.9 2.4 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 CDJ56351.1 - 2.2 7.8 18.4 0.98 9.0 0.7 2.7 2 0 0 2 2 2 0 Spt20 family Spore_coat_CotO PF14153.6 CDJ56351.1 - 3.3 7.6 17.7 8.7 6.2 1.8 2.4 2 0 0 2 2 2 0 Spore coat protein CotO CENP-O PF09496.10 CDJ56351.1 - 4 7.4 8.1 4.3 7.3 1.9 2.2 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component PACT_coil_coil PF10495.9 CDJ56351.1 - 5.8 7.6 7.3 16 6.1 1.2 3.5 3 0 0 3 3 3 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fmp27 PF10344.9 CDJ56351.1 - 5.9 4.8 7.6 2.6 6.0 3.4 1.9 2 0 0 2 2 2 0 Mitochondrial protein from FMP27 WRNPLPNID PF15017.6 CDJ56351.1 - 6.6 7.7 14.0 29 5.6 8.4 3.2 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Spt20 PF12090.8 CDJ56352.1 - 0.00026 20.7 7.0 0.00026 20.7 7.0 14.5 11 2 2 13 13 13 5 Spt20 family SUIM_assoc PF16619.5 CDJ56353.1 - 7.4e-05 22.7 0.0 7.4e-05 22.7 0.0 7.2 6 3 0 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ56353.1 - 0.002 17.8 12.0 0.002 17.8 12.0 4.6 4 1 0 4 4 4 3 Spt20 family TFIIA PF03153.13 CDJ56353.1 - 7.4 6.5 95.6 1.7 8.6 32.7 3.5 1 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ56353.1 - 9.7 6.1 10.8 2 8.3 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ56354.1 - 0.0014 18.7 28.8 0.002 18.2 28.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ56354.1 - 0.59 9.7 20.6 0.74 9.4 20.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_Helicase PF02689.14 CDJ56355.1 - 0.2 9.5 0.0 0.22 9.4 0.0 1.0 1 0 0 1 1 1 0 Helicase Pex14_N PF04695.13 CDJ56356.1 - 0.012 16.3 17.1 0.014 16.1 17.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-N PF05238.13 CDJ56356.1 - 0.036 13.4 5.4 0.041 13.2 5.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TFIIA PF03153.13 CDJ56356.1 - 0.042 13.9 27.2 0.045 13.8 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 CDJ56356.1 - 0.046 12.9 17.1 0.054 12.7 17.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region CCDC53 PF10152.9 CDJ56356.1 - 0.053 13.9 11.8 0.058 13.8 11.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAT1 PF09770.9 CDJ56356.1 - 0.063 11.6 18.7 0.066 11.5 18.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1644 PF07800.12 CDJ56356.1 - 0.22 11.6 6.4 0.28 11.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Suf PF05843.14 CDJ56356.1 - 0.22 11.5 15.6 0.23 11.4 15.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ56356.1 - 0.27 9.9 32.7 0.28 9.8 32.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.12 CDJ56356.1 - 0.36 9.7 13.8 0.37 9.7 13.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.6 CDJ56356.1 - 0.36 10.7 15.4 0.42 10.5 15.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2072 PF09845.9 CDJ56356.1 - 0.39 11.0 5.9 0.53 10.5 5.9 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF3408 PF11888.8 CDJ56356.1 - 0.4 10.8 11.6 0.53 10.4 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peroxin-13_N PF04088.13 CDJ56356.1 - 0.49 10.7 4.4 0.58 10.4 4.4 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SpoIIP PF07454.11 CDJ56356.1 - 0.5 9.8 9.9 0.57 9.6 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Baculo_PP31 PF05311.11 CDJ56356.1 - 0.57 9.6 7.5 0.59 9.6 7.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Presenilin PF01080.17 CDJ56356.1 - 0.61 8.8 13.4 0.62 8.8 13.4 1.0 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CDJ56356.1 - 0.63 10.2 7.5 0.75 10.0 7.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDJ56356.1 - 0.65 9.8 9.7 0.73 9.6 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ56356.1 - 0.68 10.1 10.5 0.8 9.8 10.5 1.0 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.14 CDJ56356.1 - 0.83 9.4 7.5 0.94 9.2 7.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 CDJ56356.1 - 0.85 9.0 15.2 0.98 8.8 15.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Coilin_N PF15862.5 CDJ56356.1 - 1.1 9.1 11.2 1.4 8.7 11.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus FAM70 PF14967.6 CDJ56356.1 - 1.2 8.5 6.1 1.3 8.4 6.1 1.0 1 0 0 1 1 1 0 FAM70 protein EOS1 PF12326.8 CDJ56356.1 - 1.3 8.9 3.6 1.3 8.9 3.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein Band_3_cyto PF07565.13 CDJ56356.1 - 1.3 8.7 8.8 1.4 8.7 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ56356.1 - 1.4 8.7 5.7 1.4 8.6 5.7 1.1 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 CDJ56356.1 - 2 8.3 6.3 2 8.3 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TERB2 PF15101.6 CDJ56356.1 - 2.4 8.2 14.8 2.8 8.0 14.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 CDJ56356.1 - 2.8 7.9 7.8 3 7.8 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.6 CDJ56356.1 - 3 8.2 7.4 4 7.8 7.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ALMT PF11744.8 CDJ56356.1 - 3.2 6.5 5.4 3 6.6 5.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ctr PF04145.15 CDJ56356.1 - 3.8 8.1 5.8 4.3 7.9 5.8 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Ndc1_Nup PF09531.10 CDJ56356.1 - 4 6.0 10.2 3.8 6.1 10.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 CDJ56356.1 - 4.5 5.1 10.4 4.7 5.0 10.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CDJ56356.1 - 5.7 6.2 13.4 6.1 6.1 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.15 CDJ56356.1 - 6.8 5.5 5.8 7.2 5.4 5.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 CDJ56356.1 - 7 5.6 7.1 7.8 5.4 7.1 1.1 1 0 0 1 1 1 0 CLN3 protein MAJIN PF15077.6 CDJ56356.1 - 7.1 6.3 8.9 7.2 6.3 8.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3464 PF11947.8 CDJ56356.1 - 8.1 6.2 15.2 15 5.3 15.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF5576 PF17739.1 CDJ56357.1 - 3.4 7.8 8.1 0.36 10.9 1.3 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5576) eIF-3_zeta PF05091.12 CDJ56358.1 - 0.00033 19.8 21.6 0.00033 19.8 21.6 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ56358.1 - 2.9 8.4 49.5 0.027 15.1 21.5 2.2 2 0 0 2 2 2 0 TCP family transcription factor SR-25 PF10500.9 CDJ56358.1 - 5.7 6.5 83.5 0.23 11.0 36.6 2.8 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein LisH PF08513.11 CDJ56359.1 - 0.066 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 LisH GTP1_OBG PF01018.22 CDJ56363.1 - 4.2e-20 71.9 0.1 4.2e-20 71.9 0.1 1.8 2 0 0 2 2 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ56363.1 - 1.1e-10 41.6 0.0 2.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DDHD PF02862.17 CDJ56363.1 - 0.0051 17.0 8.1 0.0087 16.3 8.1 1.4 1 0 0 1 1 1 1 DDHD domain AAA_21 PF13304.6 CDJ56363.1 - 0.063 13.1 0.9 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4746 PF15928.5 CDJ56363.1 - 0.28 10.6 13.8 0.54 9.6 13.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Caldesmon PF02029.15 CDJ56363.1 - 0.33 9.7 29.5 0.46 9.2 29.5 1.1 1 0 0 1 1 1 0 Caldesmon Ureide_permease PF07168.11 CDJ56363.1 - 0.4 9.4 2.8 0.61 8.8 2.8 1.4 1 0 0 1 1 1 0 Ureide permease GTP_EFTU PF00009.27 CDJ56363.1 - 0.65 9.5 3.2 7.1 6.1 0.0 3.1 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain RR_TM4-6 PF06459.12 CDJ56363.1 - 1.2 8.9 28.4 2 8.2 28.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ56363.1 - 1.3 8.0 22.1 1.9 7.5 22.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ56363.1 - 1.9 7.2 26.3 2.8 6.6 26.3 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ56363.1 - 2.5 7.0 23.4 4.1 6.3 23.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 CDJ56363.1 - 2.7 6.0 17.8 4.8 5.1 17.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ56363.1 - 2.8 6.8 9.6 4.4 6.2 9.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CDJ56363.1 - 3.8 7.2 19.6 6.5 6.5 19.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Velvet PF11754.8 CDJ56363.1 - 4.1 7.3 16.2 9.2 6.1 16.2 1.5 1 0 0 1 1 1 0 Velvet factor AAA_15 PF13175.6 CDJ56363.1 - 4.6 6.9 15.5 20 4.8 15.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ56363.1 - 6.8 6.7 17.2 46 4.0 17.2 2.2 1 1 0 1 1 1 0 Dynamin family Peptidase_U57 PF05582.12 CDJ56363.1 - 7.1 5.8 10.3 14 4.9 10.3 1.6 1 0 0 1 1 1 0 YabG peptidase U57 DUF4050 PF13259.6 CDJ56363.1 - 9.4 6.5 22.2 21 5.4 22.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Aminotran_5 PF00266.19 CDJ56364.1 - 1.1e-13 50.9 8.4 6.1e-05 22.1 0.1 4.9 4 1 0 4 4 4 3 Aminotransferase class-V ATP_bind_3 PF01171.20 CDJ56364.1 - 2.9e-13 50.0 0.0 2.9e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 PP-loop family RskA PF10099.9 CDJ56364.1 - 0.004 17.5 14.4 0.004 17.5 14.4 12.9 5 3 2 8 8 8 2 Anti-sigma-K factor rskA Glycos_transf_2 PF00535.26 CDJ56365.1 - 2.3e-05 24.3 0.0 5.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Spt20 PF12090.8 CDJ56365.1 - 0.02 14.5 29.8 1.5 8.4 12.7 4.1 4 0 0 4 4 4 0 Spt20 family Tmemb_9 PF05434.11 CDJ56365.1 - 0.045 13.6 0.1 0.19 11.6 0.0 2.0 1 1 1 2 2 2 0 TMEM9 Glyco_tranf_2_3 PF13641.6 CDJ56365.1 - 0.054 13.4 0.3 0.093 12.6 0.3 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF4834 PF16118.5 CDJ56365.1 - 0.058 14.4 0.1 0.058 14.4 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ56365.1 - 0.14 10.9 2.0 0.18 10.6 0.6 1.8 2 0 0 2 2 2 0 Presenilin Ctr PF04145.15 CDJ56365.1 - 0.39 11.3 5.4 0.11 13.1 0.1 2.5 2 1 0 2 2 2 0 Ctr copper transporter family Raffinose_syn PF05691.12 CDJ56366.1 - 4.2e-10 38.1 0.0 4.7e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_2b PF00587.25 CDJ56367.1 - 0.00014 21.9 0.3 0.00014 21.9 0.3 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Med3 PF11593.8 CDJ56367.1 - 0.00059 19.1 3.1 0.00059 19.1 3.1 3.4 2 1 1 3 3 3 1 Mediator complex subunit 3 fungal Velvet PF11754.8 CDJ56367.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.5 2 1 0 2 2 2 0 Velvet factor Tmemb_cc2 PF10267.9 CDJ56367.1 - 0.057 12.6 35.9 0.017 14.3 21.3 2.3 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein BAF1_ABF1 PF04684.13 CDJ56367.1 - 0.091 11.8 26.5 0.14 11.2 5.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF572 PF04502.13 CDJ56367.1 - 0.12 12.0 21.2 0.2 11.3 21.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lig_chan PF00060.26 CDJ56367.1 - 2.1 8.2 5.0 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel DUF4407 PF14362.6 CDJ56367.1 - 2.6 7.3 47.2 0.33 10.3 31.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CDJ56367.1 - 3.7 7.7 54.0 0.13 12.5 33.9 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) KRTAP PF11759.8 CDJ56367.1 - 4.5 7.9 22.4 13 6.5 22.4 1.7 1 0 0 1 1 1 0 Keratin-associated matrix DHH PF01368.20 CDJ56368.1 - 3.5e-10 40.0 0.0 1.3e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 DHH family DUF2722 PF10846.8 CDJ56368.1 - 0.00031 19.8 0.7 0.00031 19.8 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ56368.1 - 0.0072 16.0 34.9 0.073 12.7 14.0 2.4 2 0 0 2 2 2 2 Spt20 family Med15 PF09606.10 CDJ56368.1 - 0.11 11.2 31.3 0.086 11.5 7.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal NPR1_interact PF15699.5 CDJ56368.1 - 0.14 12.8 6.5 0.45 11.2 6.5 1.8 1 0 0 1 1 1 0 NPR1 interacting Neur_chan_memb PF02932.16 CDJ56368.1 - 0.68 9.9 3.3 0.98 9.4 3.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ56368.1 - 0.86 7.8 17.0 1.1 7.4 17.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 CDJ56368.1 - 1.4 7.6 6.0 2.5 6.7 6.0 1.4 1 0 0 1 1 1 0 Presenilin DUF3381 PF11861.8 CDJ56368.1 - 1.5 8.6 11.1 3.7 7.3 11.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Roughex PF06020.11 CDJ56368.1 - 2 7.5 12.3 2 7.4 3.0 2.4 2 0 0 2 2 2 0 Drosophila roughex protein CNDH2_N PF06278.11 CDJ56368.1 - 3.4 7.9 8.9 3.5 7.9 0.4 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4834 PF16118.5 CDJ56368.1 - 4.2 8.4 10.8 8.1 7.5 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ56369.1 - 0.00024 21.2 24.5 0.00026 21.1 24.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CDJ56369.1 - 0.00058 19.2 8.3 0.00066 19.0 8.3 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein NST1 PF13945.6 CDJ56369.1 - 0.0067 16.6 17.8 0.01 16.0 17.8 1.3 1 0 0 1 1 1 1 Salt tolerance down-regulator DUF572 PF04502.13 CDJ56369.1 - 0.051 13.2 11.8 0.053 13.1 11.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4207 PF13904.6 CDJ56369.1 - 0.15 11.7 26.6 0.23 11.1 26.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) FSA_C PF10479.9 CDJ56369.1 - 0.16 10.0 2.9 0.19 9.9 2.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MMR1 PF08505.10 CDJ56369.1 - 0.21 11.8 18.3 0.25 11.6 18.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ56369.1 - 0.24 10.1 15.3 0.25 10.0 15.3 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CDJ56369.1 - 0.26 10.7 14.3 0.32 10.4 14.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pinin_SDK_memA PF04696.13 CDJ56369.1 - 0.29 11.2 23.4 0.57 10.2 23.4 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region FAM76 PF16046.5 CDJ56369.1 - 0.36 10.2 13.0 0.46 9.8 13.0 1.1 1 0 0 1 1 1 0 FAM76 protein CLN3 PF02487.17 CDJ56369.1 - 0.44 9.5 7.3 0.46 9.5 7.3 1.3 1 0 0 1 1 1 0 CLN3 protein MPM1 PF17234.2 CDJ56369.1 - 0.5 10.6 12.9 0.73 10.1 12.9 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 BAF1_ABF1 PF04684.13 CDJ56369.1 - 0.64 9.0 19.4 0.77 8.8 19.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Bul1_N PF04425.12 CDJ56369.1 - 0.88 8.2 8.1 0.96 8.1 8.1 1.2 1 0 0 1 1 1 0 Bul1 N terminus LCD1 PF09798.9 CDJ56369.1 - 0.95 7.9 12.9 1.1 7.7 12.9 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein CSRNP_N PF16019.5 CDJ56369.1 - 1 9.2 10.9 1.4 8.8 10.9 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ndc1_Nup PF09531.10 CDJ56369.1 - 1.3 7.6 14.7 1.4 7.5 14.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tfb4 PF03850.14 CDJ56369.1 - 1.4 8.4 7.7 1.6 8.2 7.7 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 GREB1 PF15782.5 CDJ56369.1 - 1.5 5.9 11.1 1.5 5.9 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CDJ56369.1 - 1.5 7.9 3.2 1.4 8.1 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ56369.1 - 1.8 6.8 12.1 2.1 6.5 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ56369.1 - 3 6.5 12.9 3.6 6.3 12.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2722 PF10846.8 CDJ56369.1 - 3.5 6.5 31.4 6.2 5.6 31.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Gti1_Pac2 PF09729.9 CDJ56369.1 - 3.6 7.6 10.7 4.9 7.2 10.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family CNDH2_C PF16858.5 CDJ56369.1 - 3.9 7.3 17.2 4.9 6.9 17.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Otopetrin PF03189.13 CDJ56369.1 - 3.9 6.2 6.5 4 6.2 6.5 1.1 1 0 0 1 1 1 0 Otopetrin Peptidase_S64 PF08192.11 CDJ56369.1 - 4.6 5.6 12.7 5.6 5.3 12.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ureide_permease PF07168.11 CDJ56369.1 - 4.6 5.9 6.3 5.4 5.7 6.3 1.3 1 0 0 1 1 1 0 Ureide permease Cellulose_synt PF03552.14 CDJ56369.1 - 4.6 5.6 6.5 4.9 5.5 6.5 1.0 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.9 CDJ56369.1 - 5.7 5.1 23.5 5.7 5.1 23.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF913 PF06025.12 CDJ56369.1 - 5.9 5.8 10.7 6.7 5.6 10.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RIFIN PF02009.16 CDJ56369.1 - 6.7 6.5 15.4 8.4 6.2 15.4 1.3 1 0 0 1 1 1 0 Rifin FAM60A PF15396.6 CDJ56369.1 - 6.8 6.6 8.8 9.5 6.2 8.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A V_ATPase_I PF01496.19 CDJ56369.1 - 8 4.2 15.8 3.1e+02 -1.0 19.8 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ56369.1 - 8.3 6.1 12.9 12 5.5 12.9 1.3 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 CDJ56369.1 - 8.6 5.8 11.7 12 5.4 11.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MIF4G_like_2 PF09090.11 CDJ56369.1 - 9.7 5.6 16.0 12 5.2 16.0 1.1 1 0 0 1 1 1 0 MIF4G like UBA PF00627.31 CDJ56370.1 - 1.2e-22 79.4 11.6 1.5e-13 50.3 2.5 2.8 2 0 0 2 2 2 2 UBA/TS-N domain DUF2722 PF10846.8 CDJ56370.1 - 0.00013 21.1 13.7 0.00018 20.6 13.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) WIYLD PF10440.9 CDJ56370.1 - 0.0081 15.9 0.2 4 7.3 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain Suf PF05843.14 CDJ56370.1 - 0.012 15.7 11.0 0.021 14.8 11.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 CDJ56370.1 - 0.021 13.8 9.3 0.032 13.2 9.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4661 PF15576.6 CDJ56370.1 - 0.028 14.4 6.2 0.042 13.8 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PAT1 PF09770.9 CDJ56370.1 - 0.064 11.5 19.4 0.083 11.1 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endonuc_Holl PF10107.9 CDJ56370.1 - 0.13 12.1 2.2 0.23 11.3 2.2 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SpoIIP PF07454.11 CDJ56370.1 - 0.26 10.7 7.7 0.29 10.5 6.6 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ56370.1 - 0.4 10.8 8.6 0.86 9.8 8.6 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 CDJ56370.1 - 0.43 8.4 5.3 0.72 7.7 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FHIPEP PF00771.20 CDJ56370.1 - 0.45 8.9 5.9 0.62 8.5 5.9 1.1 1 0 0 1 1 1 0 FHIPEP family Connexin PF00029.19 CDJ56370.1 - 0.62 9.8 2.4 0.87 9.3 2.4 1.2 1 0 0 1 1 1 0 Connexin EPL1 PF10513.9 CDJ56370.1 - 0.7 10.3 9.2 0.22 11.9 5.7 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Hamartin PF04388.12 CDJ56370.1 - 0.75 8.4 12.7 1 7.9 12.7 1.2 1 0 0 1 1 1 0 Hamartin protein DUF775 PF05603.12 CDJ56370.1 - 0.85 9.1 14.3 0.59 9.6 11.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) TERB2 PF15101.6 CDJ56370.1 - 1.1 9.3 11.2 1.9 8.5 11.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MMU163 PF17119.5 CDJ56370.1 - 1.3 8.1 4.6 2.3 7.3 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis EIIBC-GUT_N PF03612.14 CDJ56370.1 - 1.4 8.7 6.1 2.6 7.7 6.1 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ndc1_Nup PF09531.10 CDJ56370.1 - 1.8 7.2 11.1 2.1 7.0 11.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Syntaxin-18_N PF10496.9 CDJ56370.1 - 1.8 8.8 6.6 53 4.2 4.4 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3464 PF11947.8 CDJ56370.1 - 1.8 8.3 7.3 3.1 7.5 7.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Roughex PF06020.11 CDJ56370.1 - 2.2 7.3 16.7 3.7 6.6 16.7 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 CDJ56370.1 - 2.2 8.3 8.7 3.8 7.5 8.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TCP PF03634.13 CDJ56370.1 - 2.9 8.5 13.5 6.2 7.4 13.5 1.6 1 0 0 1 1 1 0 TCP family transcription factor Velvet PF11754.8 CDJ56370.1 - 3.2 7.6 15.0 4.7 7.1 15.0 1.2 1 0 0 1 1 1 0 Velvet factor FAM60A PF15396.6 CDJ56370.1 - 3.8 7.5 6.1 6.2 6.8 6.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Ctr PF04145.15 CDJ56370.1 - 4.2 8.0 4.4 7.8 7.1 4.4 1.5 1 0 0 1 1 1 0 Ctr copper transporter family SMYLE_N PF18615.1 CDJ56370.1 - 4.5 6.7 13.3 7 6.1 13.3 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Raftlin PF15250.6 CDJ56370.1 - 5 5.8 11.5 6.5 5.4 11.5 1.1 1 0 0 1 1 1 0 Raftlin DUF4834 PF16118.5 CDJ56370.1 - 5.9 7.9 11.6 17 6.5 11.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) LIM_bind PF01803.16 CDJ56370.1 - 6.4 6.2 11.2 7.4 6.0 10.3 1.6 2 0 0 2 2 2 0 LIM-domain binding protein Coilin_N PF15862.5 CDJ56370.1 - 8.6 6.2 12.9 21 4.9 12.9 1.6 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 CDJ56370.1 - 9.6 4.9 16.1 13 4.4 16.1 1.2 1 0 0 1 1 1 0 Presenilin Rad60-SLD PF11976.8 CDJ56371.1 - 5.6e-23 80.6 0.0 6.8e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ56371.1 - 3.4e-10 39.5 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Spt20 PF12090.8 CDJ56372.1 - 0.0015 18.2 12.2 0.0015 18.2 12.2 3.7 3 1 0 3 3 3 2 Spt20 family zf-CSL PF05207.13 CDJ56372.1 - 0.026 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 CSL zinc finger PI3K_1B_p101 PF10486.9 CDJ56372.1 - 0.45 8.2 8.6 0.67 7.7 2.8 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit T2SSM PF04612.12 CDJ56374.1 - 0.0056 16.7 7.0 0.0056 16.7 7.0 5.2 4 1 0 5 5 4 1 Type II secretion system (T2SS), protein M Hira PF07569.11 CDJ56374.1 - 0.0091 15.7 0.0 0.0091 15.7 0.0 2.7 3 0 0 3 3 2 1 TUP1-like enhancer of split EIIBC-GUT_N PF03612.14 CDJ56374.1 - 0.0091 15.8 3.8 0.0091 15.8 3.8 2.4 2 0 0 2 2 2 1 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 CDJ56374.1 - 0.028 14.2 1.0 0.062 13.0 1.0 1.5 1 0 0 1 1 1 0 Connexin BSMAP PF12280.8 CDJ56374.1 - 0.052 13.8 4.8 1.2 9.3 1.6 3.1 3 0 0 3 3 3 0 Brain specific membrane anchored protein V_ATPase_I PF01496.19 CDJ56374.1 - 0.1 10.5 3.1 0.19 9.6 3.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 CDJ56374.1 - 0.5 10.0 6.9 0.036 13.7 0.7 2.2 2 0 0 2 2 2 0 FAM176 family CLN3 PF02487.17 CDJ56374.1 - 0.5 9.3 3.6 2 7.4 3.6 2.0 1 0 0 1 1 1 0 CLN3 protein DUF4199 PF13858.6 CDJ56374.1 - 1.1 9.6 6.9 0.22 11.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) SLC12 PF03522.15 CDJ56374.1 - 1.7 7.6 8.1 0.052 12.6 0.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Sec62 PF03839.16 CDJ56374.1 - 3.8 7.0 5.3 0.62 9.5 0.9 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 MCU PF04678.13 CDJ56374.1 - 4.2 7.4 8.7 1.9 8.5 0.8 2.9 3 0 0 3 3 3 0 Mitochondrial calcium uniporter SpoIIP PF07454.11 CDJ56374.1 - 6 6.2 13.6 0.52 9.7 7.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ56374.1 - 7.7 5.4 11.4 0.31 10.0 5.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Herpes_capsid PF06112.11 CDJ56378.1 - 0.0039 17.3 12.3 0.0039 17.3 12.3 3.3 2 1 1 3 3 3 1 Gammaherpesvirus capsid protein COX6B PF02297.17 CDJ56378.1 - 0.057 13.7 5.9 0.13 12.5 5.9 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3043 PF11241.8 CDJ56378.1 - 8.3 6.4 7.7 14 5.7 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Transposase_24 PF03004.14 CDJ56379.1 - 0.025 14.7 4.2 0.032 14.3 4.2 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF4148 PF13663.6 CDJ56379.1 - 0.065 13.4 6.3 0.11 12.7 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DUF3824 PF12868.7 CDJ56379.1 - 0.16 12.6 5.6 0.23 12.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) CbiD PF01888.17 CDJ56379.1 - 0.77 9.0 3.8 0.91 8.8 3.8 1.2 1 0 0 1 1 1 0 CbiD PepSY_2 PF13670.6 CDJ56379.1 - 1.3 9.1 8.9 1.9 8.5 8.9 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Apt1 PF10351.9 CDJ56379.1 - 2.1 7.1 18.7 2.1 7.1 18.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_60s PF00428.19 CDJ56379.1 - 2.8 8.6 11.1 4.6 7.9 11.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPX PF03105.19 CDJ56379.1 - 5.1 6.9 17.2 5.7 6.8 17.2 1.0 1 0 0 1 1 1 0 SPX domain MAP70 PF07058.11 CDJ56379.1 - 8.9 4.9 14.3 10 4.8 14.3 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 Presenilin PF01080.17 CDJ56379.1 - 9 4.9 12.7 9.9 4.8 12.7 1.0 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ56379.1 - 9.1 5.7 7.9 12 5.3 7.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ56380.1 - 0.062 13.3 67.1 0.63 10.0 19.9 3.1 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit FapA PF03961.13 CDJ56380.1 - 1.5 7.4 8.6 2.8 6.4 8.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A RAP1 PF07218.11 CDJ56381.1 - 0.00038 18.9 0.7 0.00038 18.9 0.7 8.2 6 2 3 9 9 9 1 Rhoptry-associated protein 1 (RAP-1) Lin-8 PF03353.15 CDJ56381.1 - 0.0024 17.5 21.2 0.0024 17.5 21.2 8.9 5 2 2 8 8 8 1 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ56381.1 - 0.0054 16.4 5.6 0.0054 16.4 5.6 13.2 10 2 3 13 13 13 1 Nuclear RNA-splicing-associated protein AP2 PF00847.20 CDJ56381.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 0 AP2 domain DEAD PF00270.29 CDJ56382.1 - 2.4e-19 69.8 0.0 6.7e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ56382.1 - 4.1e-09 36.8 0.1 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 CDJ56382.1 - 1e-05 25.7 0.1 5.9e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 SPRY domain SUIM_assoc PF16619.5 CDJ56382.1 - 0.0036 17.3 5.1 0.017 15.2 5.1 2.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2656 PF10847.8 CDJ56382.1 - 0.63 10.1 3.7 2.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2656) Spt20 PF12090.8 CDJ56382.1 - 1.8 8.1 10.8 4.3 6.9 10.8 1.6 1 0 0 1 1 1 0 Spt20 family RskA PF10099.9 CDJ56383.1 - 4.2e-06 27.2 0.0 4.2e-06 27.2 0.0 4.2 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Merozoite_SPAM PF07133.11 CDJ56383.1 - 5.5e-05 23.2 71.5 5.5e-05 23.2 71.5 2.9 3 1 0 3 3 3 1 Merozoite surface protein (SPAM) DUF1772 PF08592.11 CDJ56383.1 - 3.1 8.1 9.7 26 5.1 9.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) BUD22 PF09073.10 CDJ56383.1 - 3.2 7.0 74.4 0.0036 16.7 56.5 2.3 2 0 0 2 2 2 0 BUD22 Collagen PF01391.18 CDJ56384.1 - 0.0042 16.8 26.8 0.012 15.4 26.8 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SUIM_assoc PF16619.5 CDJ56386.1 - 3.2e-08 33.5 7.0 6.6e-05 22.9 0.0 3.8 4 1 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 PPP4R2 PF09184.11 CDJ56386.1 - 0.00058 19.5 3.0 0.00058 19.5 3.0 2.5 2 1 0 2 2 2 1 PPP4R2 FAA_hydrolase_N PF09298.11 CDJ56386.1 - 0.05 13.8 0.6 0.24 11.6 0.6 2.2 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal TFIIA PF03153.13 CDJ56386.1 - 0.074 13.0 33.8 0.43 10.5 10.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ56386.1 - 0.94 8.5 40.3 0.43 9.6 11.3 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4834 PF16118.5 CDJ56387.1 - 0.0067 17.4 24.4 0.013 16.5 4.7 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) WBP-1 PF11669.8 CDJ56387.1 - 0.57 10.8 13.7 2.6 8.7 0.8 4.0 3 0 0 3 3 3 0 WW domain-binding protein 1 Hid1 PF12722.7 CDJ56387.1 - 0.59 8.2 22.1 0.19 9.8 15.9 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 CDJ56387.1 - 1.9 8.4 61.5 1.9 8.4 10.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDJ56387.1 - 3.4 7.3 30.1 3.3 7.4 22.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 CDJ56387.1 - 6.9 5.2 23.8 4.6 5.8 16.5 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 CDJ56387.1 - 8 4.6 23.6 1.8 6.7 17.2 2.2 2 0 0 2 2 2 0 CDC45-like protein PGI PF00342.19 CDJ56388.1 - 6.5e-192 638.4 0.0 8.1e-192 638.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Peptidase_M24 PF00557.24 CDJ56391.1 - 2.3e-10 40.5 0.1 1.1e-09 38.3 0.1 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 2TM PF13239.6 CDJ56392.1 - 0.5 10.7 3.1 1.9 8.8 1.5 2.9 2 0 0 2 2 2 0 2TM domain S-AdoMet_synt_C PF02773.16 CDJ56394.1 - 9.1e-53 178.0 0.3 2.8e-52 176.4 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDJ56394.1 - 7e-46 155.4 0.0 1.7e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDJ56394.1 - 9.5e-44 148.1 0.2 1.8e-43 147.2 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Collagen PF01391.18 CDJ56395.1 - 0.14 12.0 21.0 0.28 11.0 21.0 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RRM_1 PF00076.22 CDJ56397.1 - 5.3e-14 51.8 0.0 7.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.11 CDJ56397.1 - 6.4 4.7 5.5 7.9 4.4 5.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein TPR_2 PF07719.17 CDJ56398.1 - 0.0032 17.5 0.4 0.074 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ56398.1 - 0.04 14.0 0.1 0.46 10.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56398.1 - 0.1 12.5 0.1 0.36 10.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIIA PF03153.13 CDJ56399.1 - 0.00086 19.4 17.5 0.00086 19.4 17.5 2.4 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ56399.1 - 0.0062 16.8 13.5 0.069 13.4 9.1 3.3 2 1 0 2 2 2 1 Anti-sigma-K factor rskA sCache_3_2 PF17203.4 CDJ56399.1 - 0.5 10.5 4.5 1.3 9.1 1.2 2.7 2 1 0 2 2 2 0 Single cache domain 3 Suf PF05843.14 CDJ56399.1 - 4.6 7.1 14.8 0.73 9.8 8.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF775 PF05603.12 CDJ56399.1 - 7 6.1 11.1 0.99 8.9 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) COX8 PF02285.15 CDJ56400.1 - 0.11 12.4 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII MORN PF02493.20 CDJ56401.1 - 3.6e-51 168.1 54.9 2.7e-06 26.9 0.4 10.3 10 0 0 10 10 10 10 MORN repeat Tudor_2 PF18104.1 CDJ56401.1 - 0.043 13.5 2.4 35 4.2 0.0 4.9 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF3048_C PF17479.2 CDJ56401.1 - 2.8 8.4 8.7 11 6.5 0.6 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Ras PF00071.22 CDJ56402.1 - 3.4e-44 150.3 0.1 2.6e-24 85.6 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 CDJ56402.1 - 6.1e-24 84.5 0.1 9.2e-20 71.1 0.0 2.1 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ56402.1 - 1.5e-06 27.8 0.1 1.8e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ56402.1 - 0.00079 19.5 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ56402.1 - 0.0011 18.3 0.0 0.0055 16.1 0.0 1.8 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ56402.1 - 0.0079 16.1 0.0 2 8.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CDJ56402.1 - 0.03 14.7 0.0 0.04 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CDJ56402.1 - 0.087 12.2 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 CDJ56402.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pkinase_Tyr PF07714.17 CDJ56403.1 - 9.4e-10 38.2 0.4 7.9e-09 35.2 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ56403.1 - 2.7e-07 30.2 0.0 3.2e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain G-patch_2 PF12656.7 CDJ56405.1 - 7.9e-11 41.9 0.0 7.9e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 G-patch domain AAA_23 PF13476.6 CDJ56405.1 - 0.0011 19.5 0.6 0.054 14.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Spt20 PF12090.8 CDJ56405.1 - 0.0069 16.0 9.9 0.0069 16.0 9.9 2.2 2 0 0 2 2 2 1 Spt20 family SR-25 PF10500.9 CDJ56405.1 - 0.011 15.3 10.7 0.011 15.3 10.7 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ56405.1 - 0.035 13.5 13.3 0.1 11.9 13.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.12 CDJ56405.1 - 0.041 13.6 0.0 0.041 13.6 0.0 2.8 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4834 PF16118.5 CDJ56405.1 - 1.4 9.9 10.2 0.5 11.4 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RAB3GAP2_N PF14655.6 CDJ56405.1 - 2.5 7.3 6.6 5.2 6.2 6.6 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BRF1 PF07741.13 CDJ56405.1 - 2.5 8.5 12.9 13 6.2 0.0 3.2 3 0 0 3 3 3 0 Brf1-like TBP-binding domain TERB2 PF15101.6 CDJ56405.1 - 3.4 7.7 8.8 8.6 6.4 2.9 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 EPL1 PF10513.9 CDJ56405.1 - 3.6 8.0 10.4 1.1 9.6 2.3 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF702 PF05142.12 CDJ56405.1 - 9.7 6.7 9.2 17 5.9 5.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) MID_MedPIWI PF18296.1 CDJ56407.1 - 0.018 14.8 1.5 0.022 14.6 1.5 1.2 1 0 0 1 1 1 0 MID domain of medPIWI NPR3 PF03666.13 CDJ56407.1 - 0.029 13.2 9.5 0.033 13.0 9.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CDJ56407.1 - 0.065 12.0 15.6 0.072 11.8 15.6 1.0 1 0 0 1 1 1 0 Presenilin Consortin_C PF15281.6 CDJ56407.1 - 0.08 12.9 1.1 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Consortin C-terminus DUF4366 PF14283.6 CDJ56407.1 - 0.16 12.0 18.0 0.79 9.8 18.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) RMP PF14996.6 CDJ56407.1 - 0.17 12.1 3.3 0.25 11.6 3.3 1.2 1 0 0 1 1 1 0 Retinal Maintenance DUF913 PF06025.12 CDJ56407.1 - 0.2 10.6 8.6 0.25 10.3 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2370 PF10176.9 CDJ56407.1 - 0.21 11.2 1.2 0.25 10.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FAM60A PF15396.6 CDJ56407.1 - 0.32 11.0 4.0 0.37 10.8 4.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Orf78 PF06024.12 CDJ56407.1 - 0.33 11.3 3.3 0.58 10.5 3.3 1.5 1 1 0 1 1 1 0 Orf78 (ac78) DcuA_DcuB PF03605.14 CDJ56407.1 - 0.33 9.8 1.2 0.41 9.5 1.2 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Zip PF02535.22 CDJ56407.1 - 0.46 9.7 11.3 0.56 9.4 11.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MDM31_MDM32 PF08118.11 CDJ56407.1 - 0.54 8.9 4.6 0.62 8.7 4.6 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Kei1 PF08552.11 CDJ56407.1 - 0.55 10.1 1.5 0.6 10.0 1.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PIP5K PF01504.18 CDJ56407.1 - 0.8 8.9 6.7 0.95 8.6 6.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4050 PF13259.6 CDJ56407.1 - 0.81 10.0 7.4 0.94 9.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4045 PF13254.6 CDJ56407.1 - 2.1 7.9 12.8 2.4 7.7 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.15 CDJ56407.1 - 2.8 6.6 14.2 3.1 6.5 14.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peroxin-13_N PF04088.13 CDJ56407.1 - 2.8 8.2 5.1 4.9 7.4 5.1 1.5 1 1 0 1 1 1 0 Peroxin 13, N-terminal region ALMT PF11744.8 CDJ56407.1 - 3 6.6 6.9 3.3 6.4 6.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MCM_bind PF09739.9 CDJ56407.1 - 3.5 6.0 10.9 3.5 5.9 10.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 CDJ56407.1 - 3.8 6.4 11.0 4.5 6.2 11.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ56407.1 - 5.3 7.0 6.7 6.1 6.8 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ56407.1 - 6 5.8 6.9 6.9 5.6 6.9 1.1 1 0 0 1 1 1 0 CLN3 protein SDA1 PF05285.12 CDJ56407.1 - 6.9 6.0 43.3 8.4 5.7 43.3 1.0 1 0 0 1 1 1 0 SDA1 Ureide_permease PF07168.11 CDJ56407.1 - 7.1 5.3 5.9 8.3 5.1 5.9 1.1 1 0 0 1 1 1 0 Ureide permease Cwf_Cwc_15 PF04889.12 CDJ56407.1 - 7.8 6.1 26.6 10 5.8 26.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DEAD PF00270.29 CDJ56408.1 - 3.9e-17 62.6 0.0 4.4e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 CDJ56408.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit IQ PF00612.27 CDJ56409.1 - 0.015 15.0 0.1 0.047 13.5 0.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Hydantoinase_B PF02538.14 CDJ56409.1 - 0.022 13.2 7.1 0.033 12.6 7.1 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase TMF_DNA_bd PF12329.8 CDJ56409.1 - 0.029 14.4 7.8 0.029 14.4 7.8 4.5 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.9 CDJ56409.1 - 3.8 7.5 4.9 1.5 8.8 1.1 2.1 2 0 0 2 2 2 0 Apolipoprotein O Urocanase PF01175.18 CDJ56409.1 - 4 7.0 11.2 0.17 11.5 2.1 2.5 2 1 0 2 2 2 0 Urocanase Rossmann-like domain GAS PF13851.6 CDJ56409.1 - 4.1 6.7 40.2 1.9 7.8 12.2 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding PI_PP_I PF18363.1 CDJ56409.1 - 4.4 7.6 8.2 0.59 10.4 1.2 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain FXR_C1 PF16096.5 CDJ56410.1 - 0.46 10.7 6.0 0.38 11.0 3.2 2.3 2 1 1 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 Zip PF02535.22 CDJ56412.1 - 0.026 13.8 3.0 0.039 13.2 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MID_MedPIWI PF18296.1 CDJ56412.1 - 1.6 8.4 7.8 3.2 7.5 3.1 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Ctr PF04145.15 CDJ56412.1 - 2.2 8.9 5.2 7.4 7.2 5.1 2.2 1 1 0 1 1 1 0 Ctr copper transporter family DUF2520 PF10728.9 CDJ56413.1 - 5.2 6.8 9.8 0.35 10.6 2.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2520) AP2 PF00847.20 CDJ56414.1 - 0.044 14.0 1.5 0.11 12.7 1.5 1.7 1 0 0 1 1 1 0 AP2 domain QH-AmDH_gamma PF08992.11 CDJ56415.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Transglycosylas PF06737.14 CDJ56415.1 - 0.11 13.2 0.3 0.11 13.2 0.3 2.8 3 0 0 3 3 3 0 Transglycosylase-like domain GST_C_3 PF14497.6 CDJ56416.1 - 0.045 13.9 0.0 0.29 11.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Gp-FAR-1 PF05823.12 CDJ56417.1 - 0.049 14.0 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glyoxalase PF00903.25 CDJ56418.1 - 3.8e-23 82.1 0.4 2.1e-09 37.7 0.2 3.1 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ56418.1 - 2.3e-09 37.5 0.1 0.00059 20.1 0.0 2.6 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.8 CDJ56418.1 - 0.00017 21.4 0.1 0.94 9.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3081) Glyoxalase_2 PF12681.7 CDJ56418.1 - 0.0016 18.4 0.0 0.2 11.6 0.0 2.8 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CDJ56418.1 - 0.0019 18.3 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain DUF755 PF05501.11 CDJ56419.1 - 0.024 14.9 24.0 0.024 14.9 24.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF755) DUF2052 PF09747.9 CDJ56420.1 - 0.0038 17.4 1.7 0.0038 17.4 1.7 7.1 6 1 0 6 6 6 2 Coiled-coil domain containing protein (DUF2052) Utp14 PF04615.13 CDJ56421.1 - 0.001 17.8 6.7 0.001 17.8 6.7 4.9 2 2 0 3 3 3 1 Utp14 protein RskA PF10099.9 CDJ56421.1 - 2.7 8.3 0.0 2.7 8.3 0.0 12.9 2 1 6 8 8 8 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ56422.1 - 1.2e-06 28.0 31.1 4.4e-05 22.9 16.0 2.3 2 0 0 2 2 2 2 Sin-like protein conserved region SpoIIP PF07454.11 CDJ56422.1 - 0.0006 19.4 10.3 0.0006 19.4 10.3 2.1 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) RskA PF10099.9 CDJ56422.1 - 0.002 18.5 26.2 0.002 18.5 26.2 4.5 1 1 1 3 3 2 2 Anti-sigma-K factor rskA PTPRCAP PF15713.5 CDJ56422.1 - 0.015 15.6 19.1 0.019 15.3 11.1 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated N6_N4_Mtase PF01555.18 CDJ56422.1 - 0.12 12.0 0.0 16 5.1 3.0 2.3 2 1 0 2 2 2 0 DNA methylase AP3D1 PF06375.11 CDJ56422.1 - 0.18 12.0 22.1 1.2 9.4 9.6 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Arb1 PF09692.10 CDJ56422.1 - 0.33 10.1 11.2 0.76 8.9 0.2 2.3 2 0 0 2 2 2 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 FAM176 PF14851.6 CDJ56422.1 - 0.51 10.0 9.6 0.044 13.5 2.7 2.4 2 0 0 2 2 2 0 FAM176 family CLN3 PF02487.17 CDJ56422.1 - 0.68 8.9 14.1 0.26 10.3 7.1 2.2 2 0 0 2 2 2 0 CLN3 protein SID-1_RNA_chan PF13965.6 CDJ56422.1 - 1.4 7.3 5.9 0.77 8.1 1.4 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FAM76 PF16046.5 CDJ56422.1 - 1.4 8.2 21.7 0.057 12.8 8.5 2.5 2 0 0 2 2 2 0 FAM76 protein DUF913 PF06025.12 CDJ56422.1 - 2.1 7.2 12.0 0.39 9.6 5.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 CDJ56422.1 - 2.5 6.1 16.6 0.093 10.8 8.5 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) AAA_23 PF13476.6 CDJ56422.1 - 4.3 7.8 27.5 2.3 8.7 14.3 2.5 2 0 0 2 2 2 0 AAA domain eIF-3_zeta PF05091.12 CDJ56422.1 - 6.1 5.7 26.5 0.82 8.6 17.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CDJ56422.1 - 8.6 6.1 24.2 4.8 6.9 17.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 CDJ56422.1 - 9.3 4.2 21.9 3.8 5.5 14.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) SAPS PF04499.15 CDJ56423.1 - 0.00013 20.9 11.2 0.00013 20.9 11.2 5.3 3 2 1 4 4 4 1 SIT4 phosphatase-associated protein CDC45 PF02724.14 CDJ56423.1 - 0.0006 18.3 7.9 0.0006 18.3 7.9 6.6 4 1 1 5 5 5 2 CDC45-like protein PAP1 PF08601.10 CDJ56423.1 - 0.015 15.1 0.0 0.015 15.1 0.0 8.6 7 2 1 8 8 8 0 Transcription factor PAP1 Rad50_zn_hook PF04423.14 CDJ56425.1 - 0.0081 16.0 0.0 0.0081 16.0 0.0 5.0 5 0 0 5 5 5 1 Rad50 zinc hook motif NAM-associated PF14303.6 CDJ56429.1 - 1 10.0 0.0 1 10.0 0.0 6.1 1 1 2 4 4 4 0 No apical meristem-associated C-terminal domain HNOBA PF07701.14 CDJ56431.1 - 0.084 12.3 1.6 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Heme NO binding associated Ndc1_Nup PF09531.10 CDJ56431.1 - 0.16 10.6 8.1 0.21 10.2 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SUIM_assoc PF16619.5 CDJ56431.1 - 2.2 8.4 28.7 1.8 8.7 8.7 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol_phi PF04931.13 CDJ56431.1 - 4.6 5.2 21.7 8.8 4.3 21.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DNA_pol_D_N PF18018.1 CDJ56432.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.3 1 1 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Hc1 PF07432.13 CDJ56432.1 - 1.4 9.3 13.1 1.8 9.0 13.1 1.2 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF2057 PF09829.9 CDJ56432.1 - 1.8 8.7 5.2 2.1 8.4 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) TTL PF03133.15 CDJ56433.1 - 3.1e-35 121.7 18.6 6.5e-27 94.4 0.0 4.6 3 1 1 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ56433.1 - 1.3e-06 27.8 0.0 1.3e-06 27.8 0.0 5.0 4 1 1 5 5 5 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDJ56433.1 - 7.6e-05 22.1 0.0 0.27 10.5 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RskA PF10099.9 CDJ56433.1 - 0.0072 16.6 6.0 0.0072 16.6 6.0 11.1 6 2 4 10 10 10 2 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ56435.1 - 1.3e-65 221.4 0.0 1.7e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56435.1 - 8.8e-31 107.1 0.0 1.5e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ56435.1 - 2.5e-05 23.8 0.4 0.00013 21.4 0.1 2.2 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 CDJ56435.1 - 0.0046 16.3 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ56435.1 - 0.0097 14.9 0.2 0.048 12.6 0.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDJ56435.1 - 0.056 13.4 0.3 1.3 8.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DAGAT PF03982.13 CDJ56436.1 - 1.1e-26 93.4 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase ABC_tran PF00005.27 CDJ56437.1 - 2.8e-33 115.3 0.0 5.2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ56437.1 - 6.6e-15 55.5 7.7 2.7e-12 46.9 7.7 2.2 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CDJ56437.1 - 0.00028 21.3 0.2 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CDJ56437.1 - 0.0023 17.8 0.0 0.0055 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDJ56437.1 - 0.011 15.9 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ56437.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CDJ56437.1 - 0.018 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 CDJ56437.1 - 0.021 14.0 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 CDJ56437.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain GpcrRhopsn4 PF10192.9 CDJ56437.1 - 0.097 12.1 0.7 0.15 11.5 0.7 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain AAA_24 PF13479.6 CDJ56437.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ56437.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 CDJ56437.1 - 0.26 11.0 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 CDJ56437.1 - 0.28 10.0 0.0 0.46 9.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_2 PF07724.14 CDJ56438.1 - 2.6e-40 138.3 0.0 6.4e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ56438.1 - 1.7e-32 111.4 1.3 1.7e-32 111.4 1.3 3.2 1 1 3 4 4 4 1 AAA lid domain AAA_5 PF07728.14 CDJ56438.1 - 3.5e-14 53.0 0.0 8.3e-13 48.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ56438.1 - 9.8e-10 39.0 0.0 4.2e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ56438.1 - 9.2e-07 29.2 1.6 6e-05 23.3 0.0 3.4 2 2 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CDJ56438.1 - 2.4e-06 27.3 0.2 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDJ56438.1 - 0.00011 22.3 0.2 0.0011 19.0 0.0 2.6 3 1 1 4 4 4 1 AAA domain AAA_18 PF13238.6 CDJ56438.1 - 0.00019 22.0 0.1 0.0015 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ56438.1 - 0.00027 21.3 2.8 0.00092 19.6 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ56438.1 - 0.002 18.0 0.3 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AFG1_ATPase PF03969.16 CDJ56438.1 - 0.0021 17.0 0.7 0.13 11.2 0.0 2.9 3 0 0 3 3 3 1 AFG1-like ATPase AAA_7 PF12775.7 CDJ56438.1 - 0.0022 17.5 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDJ56438.1 - 0.0024 17.6 0.4 0.044 13.5 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein Torsin PF06309.11 CDJ56438.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 CDJ56438.1 - 0.02 14.2 2.1 0.034 13.4 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin ABC_tran PF00005.27 CDJ56438.1 - 0.027 15.0 0.2 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_6 PF12774.7 CDJ56438.1 - 0.039 12.9 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 CDJ56438.1 - 0.042 14.2 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 CDJ56438.1 - 0.046 13.9 0.1 0.62 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CDJ56438.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta2 PF13177.6 CDJ56438.1 - 0.089 12.6 0.0 8.8 6.1 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ResIII PF04851.15 CDJ56438.1 - 0.091 12.8 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 CDJ56438.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDJ56438.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 CDJ56438.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase LUC7 PF03194.15 CDJ56438.1 - 0.29 10.8 4.1 0.51 10.0 4.1 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DUF16 PF01519.16 CDJ56438.1 - 1.2 9.6 8.1 2.2 8.8 5.1 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 ABC_tran_CTD PF16326.5 CDJ56438.1 - 3.2 8.1 15.9 0.056 13.7 3.2 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain Ribosomal_60s PF00428.19 CDJ56439.1 - 0.0072 16.9 5.2 0.0072 16.9 5.2 2.4 3 0 0 3 3 3 1 60s Acidic ribosomal protein DUF4366 PF14283.6 CDJ56440.1 - 0.015 15.4 4.2 0.015 15.4 4.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4366) BUD22 PF09073.10 CDJ56440.1 - 0.024 14.0 33.9 0.0095 15.3 16.7 2.2 2 0 0 2 2 2 0 BUD22 PEX11 PF05648.14 CDJ56440.1 - 0.15 11.5 0.1 0.15 11.5 0.1 3.1 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) Mem_trans PF03547.18 CDJ56440.1 - 0.53 8.6 9.1 1 7.7 9.1 1.4 1 0 0 1 1 1 0 Membrane transport protein eIF-3c_N PF05470.12 CDJ56440.1 - 5.5 5.2 19.8 2.3 6.4 0.1 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Macoilin PF09726.9 CDJ56441.1 - 4.3 5.8 27.3 5.7 5.4 27.3 1.3 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CDJ56441.1 - 5.3 6.6 56.3 10 5.7 21.5 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4865 PF16157.5 CDJ56442.1 - 0.0039 17.2 1.4 0.0055 16.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4865) DUF2722 PF10846.8 CDJ56442.1 - 0.0075 15.3 3.6 0.0095 14.9 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Na_trans_assoc PF06512.13 CDJ56442.1 - 0.012 15.9 1.5 0.014 15.6 1.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Apt1 PF10351.9 CDJ56442.1 - 0.022 13.7 2.6 0.028 13.3 2.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF3_subunit PF08597.10 CDJ56442.1 - 0.023 14.6 9.1 0.029 14.3 9.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Lin-8 PF03353.15 CDJ56442.1 - 0.025 14.2 3.3 0.03 13.9 3.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 CDJ56442.1 - 0.03 14.1 6.5 0.044 13.6 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IFT57 PF10498.9 CDJ56442.1 - 0.039 12.9 8.5 0.048 12.6 8.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAM176 PF14851.6 CDJ56442.1 - 0.063 12.9 3.3 0.11 12.1 3.3 1.4 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 CDJ56442.1 - 0.085 12.1 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ56442.1 - 0.14 10.9 3.1 0.15 10.8 3.1 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CDJ56442.1 - 0.16 10.7 4.2 0.21 10.3 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 CDJ56442.1 - 0.25 11.3 4.2 0.087 12.8 1.7 1.4 2 0 0 2 2 2 0 Protein Family FAM60A Plasmodium_Vir PF05795.11 CDJ56442.1 - 0.27 10.6 1.6 0.3 10.4 1.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PBP1_TM PF14812.6 CDJ56442.1 - 0.98 9.8 6.0 1.6 9.1 6.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.16 CDJ56442.1 - 1.1 8.4 5.8 1.6 7.9 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CDJ56442.1 - 1.1 7.4 7.6 1.4 7.1 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 CDJ56442.1 - 1.6 7.7 9.5 2.4 7.2 9.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF1682 PF07946.14 CDJ56442.1 - 2 7.6 8.3 2.6 7.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hid1 PF12722.7 CDJ56442.1 - 2.1 6.3 4.7 2.3 6.2 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4661 PF15576.6 CDJ56442.1 - 4.6 7.1 7.2 2.3 8.0 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) DUF4637 PF15470.6 CDJ56442.1 - 5.1 6.8 11.3 7.6 6.2 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4746 PF15928.5 CDJ56442.1 - 7.2 5.9 11.1 9.7 5.5 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4366 PF14283.6 CDJ56443.1 - 4.5 7.3 16.5 0.14 12.1 0.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4366) MASE4 PF17158.4 CDJ56444.1 - 0.035 13.4 0.5 0.17 11.2 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain DUF743 PF05332.11 CDJ56444.1 - 1.5 8.9 8.2 2.4 8.3 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF743) RskA PF10099.9 CDJ56445.1 - 0.014 15.7 4.3 0.027 14.8 4.3 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2076 PF09849.9 CDJ56445.1 - 0.63 10.0 28.8 0.013 15.6 10.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4407 PF14362.6 CDJ56446.1 - 0.0035 16.7 46.2 0.0035 16.7 46.2 8.6 1 1 7 8 8 8 1 Domain of unknown function (DUF4407) SLIDE PF09111.10 CDJ56447.1 - 1.1e-15 57.6 0.1 1.1e-15 57.6 0.1 2.7 2 1 1 3 3 3 1 SLIDE SNF2_N PF00176.23 CDJ56447.1 - 2.3e-06 26.6 2.3 2.3e-06 26.6 2.3 2.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ56447.1 - 1e-05 25.8 0.3 6.8e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 CDJ56447.1 - 0.00017 21.7 4.8 0.038 14.2 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF1086 PF06461.11 CDJ56447.1 - 0.12 12.2 2.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) Skp1 PF01466.19 CDJ56447.1 - 1.4 9.1 14.0 4.5 7.5 0.1 4.5 4 0 0 4 4 4 0 Skp1 family, dimerisation domain TPR_2 PF07719.17 CDJ56448.1 - 6.1e-21 72.8 18.8 0.0002 21.2 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56448.1 - 2.9e-19 68.0 9.5 3.5e-05 23.4 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ56448.1 - 6.9e-17 60.2 0.9 0.00045 20.2 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56448.1 - 3.4e-11 43.5 25.6 0.0057 17.1 0.1 7.4 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ56448.1 - 1.4e-10 41.3 16.0 0.0017 18.6 0.1 6.2 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ56448.1 - 2.9e-10 40.1 33.5 0.019 15.8 0.2 9.0 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ56448.1 - 6.8e-10 38.3 0.5 0.19 11.8 0.0 5.8 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56448.1 - 1.1e-06 29.2 36.5 0.004 17.8 0.1 6.8 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ56448.1 - 2.6e-06 27.1 3.8 0.25 11.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ56448.1 - 5.3e-06 26.6 9.3 0.037 14.2 0.5 5.1 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDJ56448.1 - 7.1e-05 22.9 3.0 0.31 11.5 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ56448.1 - 0.00052 20.5 13.0 20 6.1 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ56448.1 - 0.003 17.2 6.5 0.16 11.6 0.1 5.2 5 1 1 6 6 6 1 TPR repeat PPR PF01535.20 CDJ56448.1 - 0.013 15.6 0.2 31 5.1 0.0 4.4 4 0 0 4 4 4 0 PPR repeat Coatomer_E PF04733.14 CDJ56448.1 - 0.08 12.4 1.8 0.82 9.0 0.4 2.9 3 1 0 3 3 3 0 Coatomer epsilon subunit Ax_dynein_light PF10211.9 CDJ56449.1 - 3.2e-41 141.3 0.1 4.4e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain zf-RING_4 PF14570.6 CDJ56449.1 - 0.01 15.6 0.2 0.01 15.6 0.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ASH PF15780.5 CDJ56450.1 - 1.4e-05 25.2 0.0 0.0015 18.7 0.0 2.8 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Clr2 PF10383.9 CDJ56450.1 - 0.022 15.6 0.4 0.065 14.0 0.4 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF2218 PF09981.9 CDJ56450.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) LRR_9 PF14580.6 CDJ56453.1 - 0.0016 18.0 3.3 0.0033 16.9 3.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ56453.1 - 0.027 14.9 7.5 0.027 14.9 7.5 2.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ56453.1 - 0.44 10.3 7.9 0.98 9.2 6.6 2.1 1 1 1 2 2 2 0 Leucine rich repeat WD40 PF00400.32 CDJ56454.1 - 6.2e-22 77.5 13.0 2.4e-05 25.0 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56454.1 - 3.7e-12 46.4 0.0 0.022 15.1 0.0 5.2 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ56454.1 - 8.1e-06 25.0 0.0 0.0023 16.9 0.0 3.0 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDJ56454.1 - 4.8e-05 23.3 0.0 0.0033 17.3 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDJ56454.1 - 0.006 15.3 0.1 2.5 6.7 0.0 2.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CDJ56454.1 - 0.053 12.9 0.0 2.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 CDJ56454.1 - 0.069 13.7 8.8 4.7 7.8 0.0 5.3 7 0 0 7 7 7 0 PQQ-like domain EzrA PF06160.12 CDJ56455.1 - 5.8e-07 28.1 14.2 1.2e-06 27.0 14.2 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA IFT57 PF10498.9 CDJ56455.1 - 9.9e-05 21.5 15.5 0.006 15.6 7.7 2.5 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Spc7 PF08317.11 CDJ56455.1 - 0.00035 19.5 22.2 0.065 12.1 15.8 2.9 1 1 2 3 3 3 3 Spc7 kinetochore protein TarH PF02203.15 CDJ56455.1 - 0.0025 17.8 5.7 0.081 12.8 1.0 2.7 2 1 0 3 3 3 1 Tar ligand binding domain homologue DUF1664 PF07889.12 CDJ56455.1 - 0.0028 17.7 14.0 0.31 11.1 0.5 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CDJ56455.1 - 0.0036 16.0 13.1 0.0059 15.3 13.1 1.3 1 0 0 1 1 1 1 AAA domain FliJ PF02050.16 CDJ56455.1 - 0.0044 17.2 20.8 0.29 11.4 7.1 3.2 1 1 2 3 3 3 2 Flagellar FliJ protein GAS PF13851.6 CDJ56455.1 - 0.0045 16.3 19.2 0.024 14.0 17.7 2.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mer2 PF09074.10 CDJ56455.1 - 0.0066 16.3 9.5 0.0066 16.3 9.5 2.1 1 1 1 2 2 2 1 Mer2 BLOC1_2 PF10046.9 CDJ56455.1 - 0.011 16.0 15.8 0.83 10.0 0.2 4.0 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RmuC PF02646.16 CDJ56455.1 - 0.013 14.6 1.3 0.013 14.6 1.3 2.8 1 1 1 3 3 3 0 RmuC family Tup_N PF08581.10 CDJ56455.1 - 0.022 15.1 0.8 0.022 15.1 0.8 3.6 2 2 1 3 3 3 0 Tup N-terminal HMMR_N PF15905.5 CDJ56455.1 - 0.024 14.1 20.1 0.095 12.2 19.9 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 CDJ56455.1 - 0.045 13.8 10.4 3.5 7.7 5.1 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.13 CDJ56455.1 - 0.069 13.2 20.4 5.5 7.1 11.8 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Mce4_CUP1 PF11887.8 CDJ56455.1 - 0.07 12.6 0.6 0.17 11.3 0.6 1.6 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Snapin_Pallidin PF14712.6 CDJ56455.1 - 0.076 13.4 23.7 1.9 9.0 0.8 4.2 1 1 3 4 4 4 0 Snapin/Pallidin Ax_dynein_light PF10211.9 CDJ56455.1 - 0.088 12.7 14.7 0.072 13.0 2.1 2.5 1 1 0 2 2 2 0 Axonemal dynein light chain ATG16 PF08614.11 CDJ56455.1 - 0.14 12.3 25.4 1.1 9.4 12.7 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 CDJ56455.1 - 0.15 12.0 15.1 0.26 11.3 0.9 3.2 1 1 2 3 3 3 0 Laminin Domain II UPF0242 PF06785.11 CDJ56455.1 - 0.22 11.6 22.5 2.9 8.0 9.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cauli_AT PF03233.13 CDJ56455.1 - 0.27 11.1 7.8 0.27 11.1 2.1 2.4 1 1 2 3 3 3 0 Aphid transmission protein ApoB100_C PF12491.8 CDJ56455.1 - 0.33 10.9 5.2 1.3 9.1 0.1 2.8 3 0 0 3 3 2 0 Apolipoprotein B100 C terminal DUF3450 PF11932.8 CDJ56455.1 - 0.4 9.9 20.9 0.065 12.5 6.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RRF_GI PF12614.8 CDJ56455.1 - 0.54 10.4 8.4 0.11 12.7 0.6 2.9 2 1 1 3 3 3 0 Ribosome recycling factor Sec34 PF04136.15 CDJ56455.1 - 0.58 10.0 12.5 1.4 8.8 1.2 3.2 1 1 2 3 3 3 0 Sec34-like family TMPIT PF07851.13 CDJ56455.1 - 1 8.6 16.1 2.5 7.3 3.4 2.7 1 1 2 3 3 3 0 TMPIT-like protein NuiA PF07924.11 CDJ56455.1 - 1.1 9.7 5.4 19 5.7 0.0 3.5 1 1 1 3 3 3 0 Nuclease A inhibitor-like protein NPV_P10 PF05531.12 CDJ56455.1 - 1.1 9.7 9.8 1.8e+02 2.7 5.9 3.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PspB PF06667.12 CDJ56455.1 - 1.3 9.1 7.3 2.1 8.4 4.2 2.8 2 1 1 3 3 2 0 Phage shock protein B DUF948 PF06103.11 CDJ56455.1 - 1.4 9.3 4.6 15 5.9 0.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 CDJ56455.1 - 2.3 9.0 11.4 11 6.9 1.3 3.2 1 1 2 3 3 3 0 Occludin homology domain Nup54 PF13874.6 CDJ56455.1 - 2.3 8.3 19.0 2.6 8.1 4.4 3.0 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 CDJ56455.1 - 2.4 8.7 24.8 7.6 7.1 5.9 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 CDJ56455.1 - 2.6 7.5 17.6 1.4e+02 1.8 17.6 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CDJ56455.1 - 2.9 8.1 14.5 12 6.1 2.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 CDJ56455.1 - 3 8.1 11.6 4.1 7.7 0.1 4.2 2 2 3 5 5 5 0 Haemolysin XhlA Sas10_Utp3 PF04000.15 CDJ56455.1 - 3.9 8.2 10.1 1.8 9.3 1.1 3.3 2 2 1 3 3 3 0 Sas10/Utp3/C1D family FUSC PF04632.12 CDJ56455.1 - 4.1 5.8 9.1 6.1 5.2 9.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 CDJ56455.1 - 4.3 5.1 13.9 7.1 4.4 5.9 2.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Hrs_helical PF12210.8 CDJ56455.1 - 4.4 7.9 14.0 1.4 9.5 5.8 3.2 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YlqD PF11068.8 CDJ56455.1 - 4.8 7.6 18.9 2.5 8.5 5.0 2.6 1 1 0 2 2 2 0 YlqD protein FlaC_arch PF05377.11 CDJ56455.1 - 5.8 7.4 15.3 21 5.6 0.1 5.1 3 3 2 6 6 6 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 CDJ56455.1 - 6.4 6.9 25.3 1 9.5 1.4 4.8 2 2 2 4 4 4 0 TolA binding protein trimerisation DUF2203 PF09969.9 CDJ56455.1 - 8.4 7.1 13.9 27 5.5 4.5 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) ABC_tran_CTD PF16326.5 CDJ56455.1 - 8.5 6.7 21.0 33 4.8 7.9 4.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain Phage_GPO PF05929.11 CDJ56455.1 - 9.7 5.7 16.5 5.1 6.6 3.0 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Glyco_hydro_77 PF02446.17 CDJ56456.1 - 3.2e-130 435.1 0.8 1.4e-129 433.0 0.8 1.9 1 1 0 1 1 1 1 4-alpha-glucanotransferase Ribosomal_60s PF00428.19 CDJ56458.1 - 1.5e-22 79.9 10.8 2.2e-22 79.4 10.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Spt20 PF12090.8 CDJ56459.1 - 0.0022 17.6 0.3 0.0022 17.6 0.3 7.8 5 3 1 6 6 6 1 Spt20 family T_Ag_DNA_bind PF02217.16 CDJ56459.1 - 0.32 11.6 1.4 0.93 10.1 0.3 2.3 2 0 0 2 2 2 0 Origin of replication binding protein CAP_GLY PF01302.25 CDJ56460.1 - 1.9e-11 43.8 1.2 8.4e-08 32.1 0.3 2.4 2 0 0 2 2 2 2 CAP-Gly domain SDA1 PF05285.12 CDJ56460.1 - 0.0084 15.6 30.9 0.016 14.6 30.9 1.5 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 CDJ56460.1 - 0.014 14.2 46.1 0.026 13.3 46.1 1.4 1 0 0 1 1 1 0 Caldesmon DUF4834 PF16118.5 CDJ56460.1 - 0.045 14.7 6.6 0.045 14.7 6.6 5.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) RR_TM4-6 PF06459.12 CDJ56460.1 - 0.12 12.1 42.2 1.2 8.9 1.9 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PIEZO PF15917.5 CDJ56460.1 - 0.27 10.7 46.2 0.88 9.0 32.5 2.5 2 0 0 2 2 2 0 Piezo Nop53 PF07767.11 CDJ56460.1 - 0.66 9.3 52.3 0.61 9.4 37.6 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.13 CDJ56460.1 - 2.8 6.4 49.7 0.0042 15.8 39.0 1.6 2 0 0 2 2 2 0 Utp14 protein Vfa1 PF08432.10 CDJ56460.1 - 7.3 6.9 48.2 1.8 8.8 32.8 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 AAA_23 PF13476.6 CDJ56460.1 - 8.9 6.8 59.7 9.3 6.7 41.7 2.3 2 0 0 2 2 2 0 AAA domain RskA PF10099.9 CDJ56461.1 - 0.01 16.2 0.5 0.01 16.2 0.5 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Kinesin PF00225.23 CDJ56462.1 - 2.4e-43 148.3 0.6 2e-26 92.8 0.0 5.4 4 2 2 6 6 6 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ56462.1 - 2.5e-10 40.5 9.6 2.7e-09 37.1 0.1 3.7 3 0 0 3 3 3 2 Microtubule binding RskA PF10099.9 CDJ56462.1 - 0.00056 20.2 6.7 0.00056 20.2 6.7 13.7 3 2 6 11 11 11 2 Anti-sigma-K factor rskA PAP1 PF08601.10 CDJ56463.1 - 0.06 13.1 0.0 0.06 13.1 0.0 8.7 4 3 3 8 8 8 0 Transcription factor PAP1 AP2 PF00847.20 CDJ56464.1 - 1.6e-07 31.4 0.7 1.6e-07 31.4 0.7 6.3 5 0 0 5 5 5 1 AP2 domain Nop PF01798.18 CDJ56465.1 - 3.3e-80 268.9 0.1 8.1e-80 267.6 0.1 1.7 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDJ56465.1 - 8.4e-14 51.7 0.1 8.4e-14 51.7 0.1 2.8 3 1 0 3 3 3 1 NOP5NT (NUC127) domain Cdh1_DBD_1 PF18196.1 CDJ56465.1 - 0.011 16.1 11.8 0.034 14.5 11.8 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 AAA_lid_9 PF17871.1 CDJ56465.1 - 0.045 13.7 14.5 0.71 9.8 14.5 2.9 1 1 0 1 1 1 0 AAA lid domain SOG2 PF10428.9 CDJ56465.1 - 2.8 7.0 5.7 8 5.5 2.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein GAGA_bind PF06217.12 CDJ56465.1 - 7.5 6.7 9.7 17 5.6 9.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family FAM60A PF15396.6 CDJ56465.1 - 9.9 6.1 8.1 21 5.0 8.1 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CDJ56466.1 - 0.016 14.0 1.0 0.016 14.0 1.0 1.3 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 CDJ56466.1 - 0.022 15.4 0.3 0.043 14.4 0.1 1.7 1 1 0 1 1 1 0 Ctr copper transporter family SRP-alpha_N PF04086.13 CDJ56466.1 - 0.059 13.3 9.1 0.1 12.5 9.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FTO_NTD PF12933.7 CDJ56466.1 - 0.084 12.1 2.7 0.15 11.2 2.7 1.3 1 0 0 1 1 1 0 FTO catalytic domain Neur_chan_memb PF02932.16 CDJ56466.1 - 0.22 11.6 4.3 0.15 12.1 2.8 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Chorion_S16 PF05836.12 CDJ56466.1 - 0.39 11.0 0.0 0.39 11.0 0.0 3.7 2 1 2 4 4 2 0 Chorion protein S16 Folliculin PF11704.8 CDJ56466.1 - 0.65 9.9 5.6 0.042 13.7 0.8 1.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Peptidase_S49_N PF08496.10 CDJ56466.1 - 0.9 9.6 8.4 2.2 8.3 8.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dynamin_N PF00350.23 CDJ56466.1 - 1.3 9.1 6.4 0.85 9.7 1.6 2.4 3 0 0 3 3 3 0 Dynamin family CPSF100_C PF13299.6 CDJ56466.1 - 1.5 9.0 6.7 1.7 8.8 4.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 CDJ56466.1 - 1.7 7.5 9.5 2.8 6.8 9.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 CDJ56466.1 - 9.8 5.1 5.3 17 4.3 5.3 1.3 1 0 0 1 1 1 0 CLN3 protein SNF2_N PF00176.23 CDJ56467.1 - 2.8e-24 85.5 0.0 2.8e-24 85.5 0.0 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain DDHD PF02862.17 CDJ56467.1 - 0.00017 21.9 4.0 0.00017 21.8 4.0 1.1 1 0 0 1 1 1 1 DDHD domain RP-C_C PF11800.8 CDJ56467.1 - 0.0056 16.8 8.2 0.0075 16.4 8.2 1.2 1 0 0 1 1 1 1 Replication protein C C-terminal region SpoIIP PF07454.11 CDJ56467.1 - 0.02 14.4 10.0 0.026 14.0 10.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CCDC53 PF10152.9 CDJ56467.1 - 0.027 14.9 14.8 0.042 14.3 14.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 CDJ56467.1 - 0.03 13.3 6.9 0.33 9.9 8.9 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EPL1 PF10513.9 CDJ56467.1 - 0.034 14.5 10.2 0.061 13.7 10.2 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 CDJ56467.1 - 0.067 13.2 32.2 0.1 12.6 32.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ56467.1 - 0.079 11.7 16.4 0.11 11.3 16.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ56467.1 - 0.084 12.1 1.5 0.093 11.9 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ56467.1 - 0.16 12.0 11.0 0.25 11.4 11.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 CDJ56467.1 - 0.17 11.3 24.3 0.22 10.9 24.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PepSY_TM PF03929.16 CDJ56467.1 - 0.21 11.2 1.2 0.29 10.8 1.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region SARAF PF06682.12 CDJ56467.1 - 0.43 10.2 13.8 0.55 9.8 13.8 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 CDJ56467.1 - 0.5 9.0 12.3 0.65 8.6 12.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ56467.1 - 0.51 10.3 18.8 0.73 9.8 18.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF853 PF05872.12 CDJ56467.1 - 0.57 8.7 12.7 17 3.8 12.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Ureide_permease PF07168.11 CDJ56467.1 - 0.6 8.8 2.4 0.88 8.3 2.4 1.2 1 0 0 1 1 1 0 Ureide permease Otopetrin PF03189.13 CDJ56467.1 - 0.61 8.8 3.6 0.67 8.7 3.6 1.1 1 0 0 1 1 1 0 Otopetrin AFT PF08731.11 CDJ56467.1 - 0.72 10.3 10.0 0.3 11.5 7.4 1.8 2 0 0 2 2 1 0 Transcription factor AFT Cytochrom_NNT PF03264.14 CDJ56467.1 - 0.72 9.5 7.2 1.1 9.0 7.2 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF908 PF06012.12 CDJ56467.1 - 0.82 9.0 10.6 1.1 8.6 10.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pex14_N PF04695.13 CDJ56467.1 - 0.89 10.2 21.5 1.3 9.7 21.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ56467.1 - 0.93 7.7 23.8 1.1 7.4 23.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CDJ56467.1 - 0.95 8.4 7.6 1.3 8.0 7.6 1.2 1 0 0 1 1 1 0 CLN3 protein Gti1_Pac2 PF09729.9 CDJ56467.1 - 1 9.5 9.3 1.6 8.8 9.3 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4746 PF15928.5 CDJ56467.1 - 1.1 8.7 10.2 1.4 8.3 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 CDJ56467.1 - 1.1 8.7 18.8 1.4 8.4 18.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ56467.1 - 1.6 6.6 14.7 2.1 6.2 14.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ56467.1 - 1.6 8.7 11.6 2.3 8.2 11.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CDJ56467.1 - 1.8 7.5 16.4 2.6 7.0 16.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ56467.1 - 2.8 5.0 13.9 3.2 4.7 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AIF_C PF14721.6 CDJ56467.1 - 2.9 8.2 11.2 5.3 7.4 11.2 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ALMT PF11744.8 CDJ56467.1 - 3.6 6.3 13.1 4.5 6.0 13.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PTPRCAP PF15713.5 CDJ56467.1 - 3.6 7.9 17.7 5.6 7.2 17.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Folliculin PF11704.8 CDJ56467.1 - 3.8 7.4 10.0 5.8 6.7 10.0 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hid1 PF12722.7 CDJ56467.1 - 4.4 5.3 15.9 5.2 5.1 15.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIP5K PF01504.18 CDJ56467.1 - 4.5 6.4 14.3 7.5 5.7 14.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CDC45 PF02724.14 CDJ56467.1 - 4.7 5.4 13.9 6 5.0 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 CDJ56467.1 - 5 6.6 11.7 7.1 6.1 11.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Spore_coat_CotO PF14153.6 CDJ56467.1 - 5.4 6.9 25.9 8.8 6.2 25.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Peroxin-3 PF04882.12 CDJ56467.1 - 5.8 5.8 20.3 8.8 5.2 20.3 1.3 1 0 0 1 1 1 0 Peroxin-3 Gtr1_RagA PF04670.12 CDJ56467.1 - 6 6.1 15.7 19 4.5 15.6 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ctr PF04145.15 CDJ56467.1 - 6.2 7.4 5.7 12 6.6 5.7 1.5 1 0 0 1 1 1 0 Ctr copper transporter family Serinc PF03348.15 CDJ56467.1 - 7 5.5 8.2 8.7 5.1 8.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Auxin_canalis PF05703.11 CDJ56467.1 - 8.7 6.2 8.2 12 5.7 8.2 1.2 1 0 0 1 1 1 0 Auxin canalisation DUF4175 PF13779.6 CDJ56467.1 - 8.7 4.1 37.6 13 3.6 37.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.12 CDJ56467.1 - 9.7 5.9 19.1 13 5.5 19.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop53 PF07767.11 CDJ56468.1 - 6.8e-20 71.8 44.2 5.6e-18 65.5 44.2 2.1 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PALP PF00291.25 CDJ56468.1 - 0.061 12.7 7.9 0.42 10.0 2.9 2.4 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF3678 PF12435.8 CDJ56468.1 - 0.14 11.6 6.4 0.29 10.6 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF4179 PF13786.6 CDJ56468.1 - 0.34 11.4 2.3 2.5 8.7 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) MutS_V PF00488.21 CDJ56469.1 - 2.2e-10 40.9 0.3 0.0012 19.0 0.2 3.8 3 0 0 3 3 3 2 MutS domain V Spore_III_AF PF09581.10 CDJ56469.1 - 0.0007 19.7 8.8 0.0007 19.7 8.8 6.6 4 2 3 7 7 7 1 Stage III sporulation protein AF (Spore_III_AF) SUIM_assoc PF16619.5 CDJ56470.1 - 0.0047 17.0 3.3 0.0047 17.0 3.3 3.8 3 1 1 4 4 3 2 Unstructured region C-term to UIM in Ataxin3 DUF908 PF06012.12 CDJ56470.1 - 0.0067 15.9 4.7 0.013 14.9 4.7 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) AUX_IAA PF02309.16 CDJ56470.1 - 0.0082 16.0 0.3 0.018 14.9 0.3 1.5 1 1 0 1 1 1 1 AUX/IAA family SR-25 PF10500.9 CDJ56470.1 - 0.011 15.4 7.3 0.011 15.4 7.3 2.4 2 1 1 3 3 2 0 Nuclear RNA-splicing-associated protein DUF775 PF05603.12 CDJ56470.1 - 0.027 14.0 2.8 0.027 14.0 2.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF775) Phostensin_N PF13916.6 CDJ56470.1 - 0.032 14.6 0.1 0.032 14.6 0.1 3.3 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal YABBY PF04690.13 CDJ56470.1 - 0.047 14.3 6.8 0.52 10.9 0.4 2.2 2 0 0 2 2 2 0 YABBY protein SRP9-21 PF05486.12 CDJ56470.1 - 0.13 12.7 8.1 1.5 9.3 0.2 3.0 2 1 1 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) TFIIA PF03153.13 CDJ56470.1 - 0.26 11.3 26.9 0.37 10.8 5.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ56470.1 - 0.28 12.0 40.1 0.33 11.8 12.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 FAM60A PF15396.6 CDJ56470.1 - 0.4 10.6 7.2 1.5 8.8 1.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A XK-related PF09815.9 CDJ56470.1 - 0.57 9.2 3.5 0.29 10.1 0.2 1.9 2 0 0 2 2 2 0 XK-related protein CAML PF14963.6 CDJ56470.1 - 0.73 9.9 6.1 0.64 10.1 0.4 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand INSIG PF07281.12 CDJ56470.1 - 0.85 9.2 3.8 2.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) IMUP PF15761.5 CDJ56470.1 - 1.3 9.8 10.4 0.44 11.3 6.2 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein WRNPLPNID PF15017.6 CDJ56470.1 - 3.2 8.7 19.6 3.4 8.6 1.5 3.1 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box AIF_C PF14721.6 CDJ56470.1 - 3.6 7.9 11.1 2 8.8 0.1 2.9 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIP5K PF01504.18 CDJ56470.1 - 6.1 6.0 12.5 31 3.7 12.5 1.8 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF1840 PF08895.11 CDJ56470.1 - 6.4 7.2 13.5 7.9 6.9 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Dehydrin PF00257.19 CDJ56470.1 - 7.9 7.0 22.3 0.17 12.5 7.0 2.8 2 1 0 2 2 2 0 Dehydrin PGA2 PF07543.12 CDJ56470.1 - 9.2 6.2 12.9 1 9.4 0.7 3.0 3 0 0 3 3 3 0 Protein trafficking PGA2 Brr6_like_C_C PF10104.9 CDJ56471.1 - 4.5e-06 26.5 2.8 0.00013 21.8 0.2 2.8 3 0 0 3 3 2 2 Di-sulfide bridge nucleocytoplasmic transport domain OATP PF03137.20 CDJ56471.1 - 0.012 13.9 0.0 0.012 13.9 0.0 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SurA_N_2 PF13623.6 CDJ56471.1 - 0.021 14.7 3.4 0.021 14.7 3.4 3.2 2 2 1 3 3 1 0 SurA N-terminal domain Nha1_C PF08619.10 CDJ56471.1 - 0.025 13.8 9.7 0.034 13.4 9.7 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TMEM208_SND2 PF05620.11 CDJ56471.1 - 0.031 14.1 1.8 0.031 14.1 1.8 2.5 4 0 0 4 4 4 0 SRP-independent targeting protein 2/TMEM208 SUIM_assoc PF16619.5 CDJ56471.1 - 0.033 14.3 6.3 0.033 14.3 6.3 5.0 3 1 1 4 4 2 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ56471.1 - 0.42 10.2 9.9 1.6 8.3 3.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.6 CDJ56471.1 - 0.86 10.0 3.1 17 5.9 0.0 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Synuclein PF01387.17 CDJ56471.1 - 1.5 9.0 3.7 8.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Synuclein Ctr PF04145.15 CDJ56471.1 - 2 9.0 11.5 3.3 8.3 4.0 2.3 1 1 1 2 2 2 0 Ctr copper transporter family RCR PF12273.8 CDJ56471.1 - 2.8 8.6 12.2 0.3 11.7 5.5 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red WD40 PF00400.32 CDJ56472.1 - 6.7e-14 52.1 5.2 0.26 12.2 0.0 7.0 7 0 0 7 7 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56472.1 - 2.9e-13 49.9 0.0 2.3e-06 27.8 0.0 2.9 2 1 1 3 3 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ56472.1 - 0.011 14.8 0.0 1.4 7.8 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RLL PF10036.9 CDJ56472.1 - 0.078 12.8 6.5 0.18 11.7 6.5 1.6 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein eIF-3_zeta PF05091.12 CDJ56472.1 - 0.19 10.7 10.0 0.28 10.1 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) eIF2A PF08662.11 CDJ56472.1 - 0.25 11.2 0.0 0.49 10.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A LPMO_10 PF03067.15 CDJ56472.1 - 0.3 11.7 9.7 0.89 10.2 9.7 1.8 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading SLC12 PF03522.15 CDJ56472.1 - 0.35 9.8 4.4 0.57 9.1 4.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDJ56472.1 - 0.44 8.8 17.6 0.69 8.1 17.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CDJ56472.1 - 0.54 9.7 10.2 0.88 9.0 10.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 CDJ56472.1 - 0.55 9.1 4.5 0.84 8.5 4.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.14 CDJ56472.1 - 2.2 8.2 15.0 6.1 6.7 15.0 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 CDJ56472.1 - 4.7 6.2 14.1 14 4.7 14.1 1.8 1 0 0 1 1 1 0 Drosophila roughex protein EPL1 PF10513.9 CDJ56472.1 - 5.2 7.4 12.7 0.32 11.4 7.5 1.6 2 0 0 2 2 1 0 Enhancer of polycomb-like Spt20 PF12090.8 CDJ56472.1 - 5.5 6.5 38.5 11 5.5 38.5 1.5 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 CDJ56472.1 - 5.6 6.6 7.2 13 5.5 7.2 1.5 1 0 0 1 1 1 0 FAM176 family DUF3408 PF11888.8 CDJ56472.1 - 7 6.8 14.4 18 5.5 14.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Tim54 PF11711.8 CDJ56472.1 - 7.4 5.2 11.0 16 4.2 11.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CLN3 PF02487.17 CDJ56472.1 - 8.9 5.2 7.6 19 4.1 7.6 1.5 1 0 0 1 1 1 0 CLN3 protein PAN_4 PF14295.6 CDJ56473.1 - 0.00011 22.0 1.1 0.00021 21.1 1.1 1.5 1 0 0 1 1 1 1 PAN domain LysM PF01476.20 CDJ56475.1 - 1.6e-09 37.6 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 LysM domain VirK PF06903.12 CDJ56475.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 VirK protein RPA_C PF08784.11 CDJ56475.1 - 0.16 12.7 1.0 5.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal DUF3446 PF11928.8 CDJ56475.1 - 4.5 7.6 12.0 15 6.0 0.2 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain PAP_central PF04928.17 CDJ56476.1 - 2.2e-84 282.3 0.0 3.7e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDJ56476.1 - 2e-14 53.6 0.1 3.4e-09 36.6 0.5 2.7 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDJ56476.1 - 2.9e-09 37.1 0.0 6.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SUIM_assoc PF16619.5 CDJ56476.1 - 0.067 13.3 2.1 0.16 12.0 2.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 IATP PF04568.12 CDJ56476.1 - 6.6 7.2 7.5 0.25 11.8 1.0 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP TFIIA PF03153.13 CDJ56478.1 - 0.031 14.3 38.9 0.041 13.9 38.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ56478.1 - 0.033 14.2 12.5 0.048 13.7 12.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CDJ56478.1 - 0.036 13.9 23.5 0.047 13.5 23.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Draxin PF15550.6 CDJ56478.1 - 0.055 13.3 14.7 0.084 12.7 14.7 1.3 1 0 0 1 1 1 0 Draxin LAP1C PF05609.12 CDJ56478.1 - 0.062 12.4 17.6 0.077 12.1 17.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF913 PF06025.12 CDJ56478.1 - 0.071 12.1 10.9 0.096 11.6 10.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CDJ56478.1 - 0.13 11.0 13.7 0.15 10.8 13.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 CDJ56478.1 - 0.3 9.7 15.2 0.35 9.5 15.2 1.1 1 0 0 1 1 1 0 Hamartin protein ALMT PF11744.8 CDJ56478.1 - 0.45 9.3 15.9 0.59 8.9 15.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rrn6 PF10214.9 CDJ56478.1 - 0.46 8.9 18.5 0.52 8.7 18.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Phage_GPD PF05954.11 CDJ56478.1 - 0.66 9.2 17.8 0.94 8.7 17.8 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Med13_C PF06333.12 CDJ56478.1 - 0.66 9.2 11.4 0.96 8.6 11.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CDC45 PF02724.14 CDJ56478.1 - 0.67 8.2 23.3 0.88 7.8 23.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 CDJ56478.1 - 0.68 9.3 18.7 0.92 8.9 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 CDJ56478.1 - 0.7 10.0 27.4 1.1 9.3 27.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GREB1 PF15782.5 CDJ56478.1 - 0.71 6.9 21.0 0.86 6.6 21.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 CDJ56478.1 - 0.74 9.1 18.8 1 8.6 18.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4637 PF15470.6 CDJ56478.1 - 0.83 9.4 14.9 2.4 7.8 14.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Tim54 PF11711.8 CDJ56478.1 - 0.84 8.3 16.2 1.3 7.7 16.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 CDJ56478.1 - 0.87 9.7 16.5 1.8 8.7 16.5 1.5 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 CDJ56478.1 - 0.94 8.4 24.7 1.2 8.0 24.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ArAE_2_N PF10337.9 CDJ56478.1 - 1 8.3 6.8 1.6 7.7 6.8 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal TRAP_alpha PF03896.16 CDJ56478.1 - 1 8.5 9.7 1.5 7.9 9.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 CDJ56478.1 - 1.3 9.0 20.0 2.2 8.2 20.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop53 PF07767.11 CDJ56478.1 - 1.7 8.0 31.1 2.3 7.5 31.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Lin-8 PF03353.15 CDJ56478.1 - 1.9 8.0 25.2 2.4 7.6 25.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NARP1 PF12569.8 CDJ56478.1 - 2 7.2 20.4 2.8 6.7 20.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.11 CDJ56478.1 - 2.4 8.2 20.3 3.4 7.7 20.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MMR1 PF08505.10 CDJ56478.1 - 3 8.1 23.5 5.4 7.2 23.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Macoilin PF09726.9 CDJ56478.1 - 3.2 6.2 18.7 4.3 5.8 18.7 1.1 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 CDJ56478.1 - 3.4 5.8 32.9 4.4 5.5 32.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTPRCAP PF15713.5 CDJ56478.1 - 3.5 7.9 31.3 0.89 9.8 27.2 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Ureide_permease PF07168.11 CDJ56478.1 - 3.6 6.2 7.5 5.5 5.6 7.5 1.3 1 0 0 1 1 1 0 Ureide permease VIR_N PF15912.5 CDJ56478.1 - 3.8 7.0 18.4 6.1 6.4 18.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Plasmodium_Vir PF05795.11 CDJ56478.1 - 3.9 6.8 12.6 5.3 6.4 12.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.22 CDJ56478.1 - 3.9 6.6 15.6 7 5.8 15.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ56478.1 - 4.1 5.7 7.2 4.9 5.4 7.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CCSAP PF15748.5 CDJ56478.1 - 4.8 7.3 31.5 7 6.7 31.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPP4R2 PF09184.11 CDJ56478.1 - 4.8 6.7 17.9 6.1 6.3 17.9 1.1 1 0 0 1 1 1 0 PPP4R2 Endostatin PF06482.11 CDJ56478.1 - 4.9 6.5 21.2 5.8 6.3 19.1 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF1387 PF07139.11 CDJ56478.1 - 5.5 6.6 23.5 8.1 6.1 23.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Radical_SAM_N PF08497.10 CDJ56478.1 - 5.7 6.1 12.1 7.9 5.6 12.1 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal DUF5427 PF10310.9 CDJ56478.1 - 6.9 5.5 27.8 9.2 5.1 27.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CDJ56478.1 - 7.7 5.4 22.9 10 5.0 22.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 CDJ56478.1 - 7.8 5.9 22.9 12 5.2 22.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ56478.1 - 8.5 5.7 37.2 15 4.9 37.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.16 CDJ56478.1 - 8.7 5.8 18.6 13 5.2 18.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4758 PF15950.5 CDJ56478.1 - 8.8 6.7 6.5 15 5.9 6.5 1.4 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein SUIM_assoc PF16619.5 CDJ56479.1 - 0.00041 20.4 0.0 0.00041 20.4 0.0 17.6 13 5 3 16 16 16 2 Unstructured region C-term to UIM in Ataxin3 Chorein_N PF12624.7 CDJ56479.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 6.3 6 1 1 7 7 7 1 N-terminal region of Chorein or VPS13 Ribosomal_60s PF00428.19 CDJ56479.1 - 0.012 16.2 0.9 0.012 16.2 0.9 33.6 32 4 3 35 35 35 0 60s Acidic ribosomal protein Nucleoporin_FG PF13634.6 CDJ56480.1 - 0.00039 21.2 123.0 0.0022 18.8 40.2 16.8 4 3 13 17 17 17 4 Nucleoporin FG repeat region PITH PF06201.13 CDJ56481.1 - 4.9e-14 52.8 0.0 5.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain PRCC PF10253.9 CDJ56482.1 - 6.7e-14 53.2 18.5 6.7e-14 53.2 18.5 2.9 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting RNA_pol_Rpb5_C PF01191.19 CDJ56483.1 - 3.4e-20 71.7 0.2 4.9e-20 71.2 0.2 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDJ56483.1 - 0.0001 22.8 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CDJ56483.1 - 0.00019 21.4 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease ABC_tran PF00005.27 CDJ56485.1 - 8.3e-33 113.8 0.0 1.8e-15 57.7 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDJ56485.1 - 2.4e-12 47.3 5.3 0.021 14.7 0.1 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ56485.1 - 1.1e-08 34.8 5.5 0.0024 17.3 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ56485.1 - 1.2e-06 28.5 0.0 0.074 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDJ56485.1 - 2.8e-06 27.6 0.0 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ56485.1 - 3.4e-06 26.7 2.1 0.0016 18.2 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ56485.1 - 8.8e-06 26.4 0.0 0.0047 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDJ56485.1 - 1.1e-05 25.5 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 CDJ56485.1 - 6.4e-05 23.4 0.1 0.27 11.6 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDJ56485.1 - 0.00013 21.9 0.2 0.016 15.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CDJ56485.1 - 0.00031 21.3 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDJ56485.1 - 0.00036 20.1 0.1 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 CDJ56485.1 - 0.00039 20.8 0.1 0.044 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CDJ56485.1 - 0.00047 20.3 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDJ56485.1 - 0.0011 19.2 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDJ56485.1 - 0.0012 19.2 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CDJ56485.1 - 0.0016 18.2 0.5 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CDJ56485.1 - 0.0036 17.4 0.7 0.34 11.0 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.22 CDJ56485.1 - 0.0044 16.7 1.9 0.47 10.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_27 PF13514.6 CDJ56485.1 - 0.0045 16.6 0.4 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDJ56485.1 - 0.0052 16.8 0.4 0.54 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDJ56485.1 - 0.0059 16.5 1.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 CDJ56485.1 - 0.0065 16.2 0.9 2 8.1 0.0 3.3 4 0 0 4 4 4 1 Thymidylate kinase AAA_24 PF13479.6 CDJ56485.1 - 0.0066 16.2 0.5 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CDJ56485.1 - 0.0069 15.8 0.1 0.37 10.2 0.0 2.5 3 0 0 3 3 3 1 Bacterial TniB protein G-alpha PF00503.20 CDJ56485.1 - 0.0081 15.4 0.0 0.26 10.4 0.0 2.4 2 1 0 3 3 3 1 G-protein alpha subunit SbcCD_C PF13558.6 CDJ56485.1 - 0.01 16.1 0.0 6.7 7.0 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit VirE PF05272.11 CDJ56485.1 - 0.013 15.2 0.1 10 5.8 0.0 3.0 2 1 1 3 3 3 0 Virulence-associated protein E MukB PF04310.12 CDJ56485.1 - 0.018 14.9 0.3 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 MukB N-terminal DUF815 PF05673.13 CDJ56485.1 - 0.021 14.0 0.2 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ56485.1 - 0.042 13.2 0.1 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ56485.1 - 0.042 13.1 0.2 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 CDJ56485.1 - 0.088 11.8 0.9 1.9 7.4 0.4 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 CDJ56485.1 - 0.1 11.2 1.8 0.47 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ56485.1 - 0.14 12.1 0.3 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 CDJ56485.1 - 0.28 10.5 3.6 4.2 6.6 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family EMP24_GP25L PF01105.24 CDJ56486.1 - 0.0025 17.8 9.2 0.0049 16.8 9.2 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Macoilin PF09726.9 CDJ56487.1 - 0.00077 18.2 37.6 0.00077 18.2 37.6 4.7 2 1 1 4 4 4 1 Macoilin family Borrelia_P83 PF05262.11 CDJ56488.1 - 0.00054 18.6 15.6 0.00054 18.6 15.6 3.4 2 1 1 3 3 3 1 Borrelia P83/100 protein VF530 PF09905.9 CDJ56488.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA-binding protein VF530 Ribosomal_L12 PF00542.19 CDJ56489.1 - 5.8e-06 26.6 1.2 0.0078 16.5 0.5 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Spt20 PF12090.8 CDJ56489.1 - 0.0043 16.7 21.7 0.13 11.8 9.2 2.1 2 0 0 2 2 2 2 Spt20 family Ribosomal_L12_N PF16320.5 CDJ56489.1 - 0.014 15.0 0.2 0.014 15.0 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain ADK_lid PF05191.14 CDJ56489.1 - 0.039 13.9 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF4834 PF16118.5 CDJ56489.1 - 0.24 12.4 5.2 7.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 CDJ56489.1 - 0.67 10.8 22.4 4.4 8.2 5.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Androgen_recep PF02166.16 CDJ56489.1 - 1 8.2 22.8 1 8.1 6.5 2.1 2 0 0 2 2 2 0 Androgen receptor RAB3GAP2_N PF14655.6 CDJ56489.1 - 2.8 7.1 9.6 1.9 7.7 1.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Neuregulin PF02158.15 CDJ56489.1 - 2.9 7.2 8.9 1.9 7.7 3.5 2.0 2 0 0 2 2 2 0 Neuregulin intracellular region KCNQ2_u3 PF16642.5 CDJ56489.1 - 4.9 8.2 9.0 4.4 8.3 0.5 2.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PAXNEB PF05625.11 CDJ56489.1 - 6 5.9 9.5 14 4.7 9.5 1.6 1 1 0 1 1 1 0 PAXNEB protein DUF2722 PF10846.8 CDJ56489.1 - 9.1 5.1 21.7 2.3 7.0 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ56491.1 - 0.00019 21.8 7.8 0.00019 21.8 7.8 13.1 3 3 5 8 8 8 3 Anti-sigma-K factor rskA AUX_IAA PF02309.16 CDJ56491.1 - 0.011 15.6 0.4 0.011 15.6 0.4 7.2 7 1 0 7 7 7 0 AUX/IAA family DUF4834 PF16118.5 CDJ56492.1 - 0.95 10.5 6.7 11 7.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SARAF PF06682.12 CDJ56492.1 - 5.7 6.5 9.3 7.3 6.1 2.5 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ABC_tran PF00005.27 CDJ56493.1 - 6.5e-13 49.4 0.1 1.3e-11 45.1 0.0 3.2 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 CDJ56493.1 - 0.0027 17.4 0.0 0.0027 17.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CDJ56493.1 - 0.0032 18.0 0.0 0.0032 18.0 0.0 2.7 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CDJ56493.1 - 0.0062 16.5 2.3 0.0087 16.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CDJ56493.1 - 0.61 10.4 0.0 0.61 10.4 0.0 4.7 5 1 0 5 5 5 0 AAA ATPase domain DUF2722 PF10846.8 CDJ56494.1 - 0.00013 21.1 2.6 0.00014 21.0 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ56494.1 - 0.002 17.8 9.0 0.0034 17.0 9.0 1.4 1 0 0 1 1 1 1 Spt20 family RskA PF10099.9 CDJ56494.1 - 0.013 15.8 11.8 0.17 12.2 5.3 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2367 PF10164.9 CDJ56494.1 - 0.19 12.2 0.9 0.45 11.0 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Roughex PF06020.11 CDJ56494.1 - 0.65 9.0 11.0 0.78 8.8 10.0 1.5 1 1 1 2 2 2 0 Drosophila roughex protein Ribosomal_60s PF00428.19 CDJ56494.1 - 4.4 8.0 10.9 8.5 7.0 10.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Hydrolase_3 PF08282.12 CDJ56495.1 - 4e-05 23.5 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ56495.1 - 0.0015 18.8 0.0 0.002 18.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ56495.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase SUIM_assoc PF16619.5 CDJ56496.1 - 0.27 11.3 0.0 0.27 11.3 0.0 25.9 11 6 7 18 18 18 0 Unstructured region C-term to UIM in Ataxin3 Bax1-I PF01027.20 CDJ56498.1 - 1.3e-33 116.6 34.7 1.5e-33 116.4 34.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spt20 PF12090.8 CDJ56499.1 - 0.0022 17.6 13.1 0.0022 17.6 13.1 5.3 4 1 0 4 4 3 1 Spt20 family DUF2722 PF10846.8 CDJ56499.1 - 0.0036 16.3 5.6 0.0036 16.3 5.6 6.1 5 1 0 5 5 3 2 Protein of unknown function (DUF2722) MID_MedPIWI PF18296.1 CDJ56499.1 - 0.039 13.7 0.2 0.039 13.7 0.2 4.9 3 1 0 4 4 3 0 MID domain of medPIWI PAT1 PF09770.9 CDJ56499.1 - 0.13 10.5 63.7 0.23 9.7 18.3 3.3 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 CDJ56499.1 - 0.16 11.4 34.6 0.31 10.4 8.1 3.7 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ56499.1 - 0.31 10.0 38.5 0.28 10.2 3.9 3.4 3 0 0 3 3 3 0 Solute carrier family 12 AAA_23 PF13476.6 CDJ56499.1 - 0.49 10.9 34.1 0.37 11.3 14.0 3.8 4 0 0 4 4 4 0 AAA domain SpoIIP PF07454.11 CDJ56499.1 - 2.5 7.5 41.6 0.096 12.1 12.9 3.5 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) LTV PF04180.14 CDJ56499.1 - 3 7.5 34.8 1.8 8.2 18.4 3.3 3 0 0 3 3 3 0 Low temperature viability protein HNOBA PF07701.14 CDJ56499.1 - 3.3 7.1 26.9 3.3 7.1 0.0 3.4 3 0 0 3 3 3 0 Heme NO binding associated Band_3_cyto PF07565.13 CDJ56499.1 - 4.1 7.1 37.0 4.7 6.9 7.4 3.6 3 0 0 3 3 3 0 Band 3 cytoplasmic domain SET PF00856.28 CDJ56500.1 - 6.3e-13 49.5 12.7 7.1e-13 49.3 0.0 2.9 2 2 0 2 2 1 1 SET domain DDHD PF02862.17 CDJ56500.1 - 0.0016 18.7 2.5 0.002 18.3 2.5 1.3 1 0 0 1 1 1 1 DDHD domain Tim54 PF11711.8 CDJ56500.1 - 0.0047 15.8 14.7 0.0068 15.2 14.7 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ56500.1 - 0.027 13.2 15.8 0.035 12.9 15.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 CDJ56500.1 - 0.041 12.5 10.4 0.056 12.1 10.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RR_TM4-6 PF06459.12 CDJ56500.1 - 0.043 13.6 22.7 0.062 13.1 22.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ56500.1 - 0.057 12.6 8.1 0.072 12.3 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 CDJ56500.1 - 0.066 12.7 15.1 0.098 12.1 15.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF702 PF05142.12 CDJ56500.1 - 0.074 13.5 5.4 0.13 12.7 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) eIF-3_zeta PF05091.12 CDJ56500.1 - 0.099 11.6 11.8 0.13 11.2 11.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hamartin PF04388.12 CDJ56500.1 - 0.1 11.3 9.8 0.12 11.0 9.8 1.2 1 0 0 1 1 1 0 Hamartin protein CCSAP PF15748.5 CDJ56500.1 - 0.16 12.1 19.5 0.28 11.3 19.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CSG2 PF16965.5 CDJ56500.1 - 0.22 10.4 2.6 0.31 9.9 2.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Pox_Ag35 PF03286.14 CDJ56500.1 - 0.26 11.1 21.7 0.41 10.4 21.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.12 CDJ56500.1 - 0.27 11.5 9.7 0.39 11.0 9.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Dynactin_p62 PF05502.13 CDJ56500.1 - 0.36 9.6 8.5 0.5 9.1 8.5 1.2 1 0 0 1 1 1 0 Dynactin p62 family DUF4746 PF15928.5 CDJ56500.1 - 0.4 10.1 21.9 0.63 9.4 21.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-N PF05238.13 CDJ56500.1 - 0.45 9.8 11.2 0.63 9.3 11.2 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Nucleo_P87 PF07267.11 CDJ56500.1 - 0.48 9.2 9.8 0.63 8.8 9.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt20 PF12090.8 CDJ56500.1 - 0.54 9.8 30.6 0.83 9.2 30.6 1.2 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CDJ56500.1 - 0.64 10.0 11.4 1 9.4 11.4 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TRAP_alpha PF03896.16 CDJ56500.1 - 0.67 9.1 10.3 1.3 8.2 10.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BORG_CEP PF14957.6 CDJ56500.1 - 0.73 11.0 11.7 1.3 10.2 11.7 1.4 1 0 0 1 1 1 0 Cdc42 effector TCP PF03634.13 CDJ56500.1 - 0.76 10.3 17.9 1.4 9.5 17.9 1.4 1 0 0 1 1 1 0 TCP family transcription factor AAA_11 PF13086.6 CDJ56500.1 - 0.81 9.4 14.2 1.3 8.7 14.2 1.3 1 0 0 1 1 1 0 AAA domain OATP PF03137.20 CDJ56500.1 - 1 7.5 4.3 1.4 7.1 4.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_polI_A34 PF08208.11 CDJ56500.1 - 1.1 9.2 30.8 1.8 8.6 30.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 CDJ56500.1 - 1.2 7.3 23.5 1.6 6.9 23.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 CDJ56500.1 - 1.4 7.6 5.1 1.6 7.3 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5427 PF10310.9 CDJ56500.1 - 1.4 7.8 20.6 2 7.3 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPP4R2 PF09184.11 CDJ56500.1 - 1.5 8.3 29.1 2.1 7.9 29.1 1.1 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 CDJ56500.1 - 1.9 8.3 16.6 3.4 7.5 16.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.10 CDJ56500.1 - 1.9 8.8 27.2 3.2 8.1 27.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 CDJ56500.1 - 1.9 7.3 13.4 2.7 6.9 13.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CSRNP_N PF16019.5 CDJ56500.1 - 2 8.3 13.3 4.8 7.0 13.3 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RPN2_C PF18004.1 CDJ56500.1 - 2.3 8.1 30.8 4 7.3 30.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Membralin PF09746.9 CDJ56500.1 - 2.5 7.0 7.2 3.7 6.5 7.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 CDJ56500.1 - 2.8 6.3 13.4 3.8 5.9 13.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mitofilin PF09731.9 CDJ56500.1 - 3.3 6.4 26.7 4.7 5.9 26.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GREB1 PF15782.5 CDJ56500.1 - 3.3 4.7 12.3 4.2 4.4 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CDJ56500.1 - 4.8 5.5 6.9 6.3 5.1 6.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MCM_bind PF09739.9 CDJ56500.1 - 5.5 5.3 16.0 7.8 4.8 16.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 CDJ56500.1 - 5.6 5.1 21.8 7.8 4.6 21.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ56500.1 - 5.7 5.8 17.4 8.1 5.4 17.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Cellulose_synt PF03552.14 CDJ56500.1 - 5.8 5.3 8.2 7.8 4.9 8.2 1.1 1 0 0 1 1 1 0 Cellulose synthase NPR3 PF03666.13 CDJ56500.1 - 6 5.5 20.5 8.7 5.0 20.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 CDJ56500.1 - 7 5.3 16.8 9.5 4.9 16.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDJ56500.1 - 7.1 6.6 10.4 11 6.0 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sin_N PF04801.13 CDJ56500.1 - 7.3 5.7 19.9 10 5.2 19.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region PPL5 PF18168.1 CDJ56500.1 - 7.5 5.7 17.2 11 5.2 17.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Dicty_REP PF05086.12 CDJ56500.1 - 8.6 4.2 13.3 13 3.7 13.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2828 PF11443.8 CDJ56500.1 - 8.7 4.3 16.8 12 3.8 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spt20 PF12090.8 CDJ56501.1 - 0.32 10.6 63.5 0.038 13.6 7.9 4.1 4 1 0 4 4 4 0 Spt20 family AAA_23 PF13476.6 CDJ56501.1 - 1.3 9.5 16.9 0.017 15.6 2.2 2.2 2 0 0 2 2 2 0 AAA domain PseudoU_synth_1 PF01416.20 CDJ56502.1 - 2e-12 47.5 4.5 1.9e-10 41.1 0.0 3.7 3 1 0 3 3 3 2 tRNA pseudouridine synthase PP2C PF00481.21 CDJ56503.1 - 1.3e-22 80.7 0.0 1.4e-19 70.7 0.0 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C Aminotran_1_2 PF00155.21 CDJ56504.1 - 9.7e-24 84.2 0.0 4.7e-11 42.5 0.0 3.0 1 1 2 3 3 3 3 Aminotransferase class I and II SR-25 PF10500.9 CDJ56505.1 - 0.0011 18.7 52.0 0.0011 18.7 52.0 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.13 CDJ56505.1 - 0.16 10.5 42.1 0.19 10.3 42.1 1.0 1 0 0 1 1 1 0 Utp14 protein Red1 PF07964.11 CDJ56505.1 - 0.31 9.2 32.4 0.36 9.0 32.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 BSP_II PF05432.11 CDJ56505.1 - 0.41 10.3 24.4 0.53 9.9 24.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CNDH2_C PF16858.5 CDJ56505.1 - 0.7 9.7 25.9 0.87 9.4 25.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1168 PF06658.12 CDJ56505.1 - 2.5 7.9 51.6 0.24 11.2 33.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PHD PF00628.29 CDJ56506.1 - 1.9e-11 43.7 8.1 6.8e-11 41.9 8.1 2.1 1 0 0 1 1 1 1 PHD-finger DUF4179 PF13786.6 CDJ56506.1 - 1.9 9.0 12.7 1.9 9.0 1.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) PHD_2 PF13831.6 CDJ56506.1 - 2.3 7.9 5.1 4.9 6.8 5.1 1.6 1 0 0 1 1 1 0 PHD-finger Aldedh PF00171.22 CDJ56508.1 - 1.3e-139 465.7 0.0 1.9e-139 465.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SUZ PF12752.7 CDJ56508.1 - 3.3 8.6 6.5 6.5 7.6 0.4 3.2 3 0 0 3 3 3 0 SUZ domain DNA_pol_A_exo1 PF01612.20 CDJ56509.1 - 9.4e-31 106.9 0.0 2.4e-30 105.6 0.0 1.5 2 0 0 2 2 2 1 3'-5' exonuclease Acetyltransf_1 PF00583.25 CDJ56510.1 - 7e-17 61.7 0.0 8.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ56510.1 - 1.6e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ56510.1 - 5e-12 46.1 0.0 6.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDJ56510.1 - 4.1e-08 34.0 0.0 5.2e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ56510.1 - 1.1e-05 25.4 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 CDJ56510.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CDJ56510.1 - 0.0067 16.5 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CDJ56510.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CDJ56510.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Pkinase PF00069.25 CDJ56512.1 - 4.5e-35 121.3 0.0 6.9e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56512.1 - 7.3e-09 35.3 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase CGGC PF08821.11 CDJ56512.1 - 0.056 13.6 1.5 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 CGGC domain Spt20 PF12090.8 CDJ56513.1 - 0.011 15.3 15.3 0.011 15.3 15.3 4.1 3 1 0 3 3 3 0 Spt20 family Mit_KHE1 PF10173.9 CDJ56513.1 - 6.7 6.7 18.6 1.2 9.2 13.3 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Otopetrin PF03189.13 CDJ56513.1 - 9.8 4.9 11.1 0.98 8.2 6.7 1.6 2 0 0 2 2 2 0 Otopetrin UPRTase PF14681.6 CDJ56516.1 - 3.5e-62 209.5 0.0 5.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CDJ56516.1 - 7.4e-09 35.3 0.0 1.9e-08 34.0 0.0 1.6 1 1 1 2 2 2 1 Phosphoribosyl transferase domain EF-hand_13 PF17958.1 CDJ56516.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DnaJ PF00226.31 CDJ56517.1 - 0.00071 19.7 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Exonuc_VII_L PF02601.15 CDJ56517.1 - 0.006 16.2 5.6 0.006 16.2 5.6 5.4 2 2 2 4 4 4 1 Exonuclease VII, large subunit Spt4 PF06093.13 CDJ56518.1 - 4.7e-10 39.4 0.9 2.5e-08 33.9 0.2 2.3 1 1 1 2 2 2 2 Spt4/RpoE2 zinc finger Methyltransf_13 PF08421.11 CDJ56518.1 - 0.085 13.1 0.1 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative zinc binding domain DEAD PF00270.29 CDJ56519.1 - 1.6e-13 50.8 0.0 1.6e-13 50.8 0.0 3.1 2 2 0 2 2 2 1 DEAD/DEAH box helicase SR-25 PF10500.9 CDJ56519.1 - 0.14 11.7 35.3 0.024 14.2 17.1 2.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein ATPase_2 PF01637.18 CDJ56519.1 - 0.16 11.9 0.9 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CKAP2_C PF15297.6 CDJ56519.1 - 0.64 9.1 29.1 0.15 11.1 14.1 2.3 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus CNDH2_C PF16858.5 CDJ56519.1 - 0.93 9.3 35.7 0.75 9.6 8.6 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Apt1 PF10351.9 CDJ56519.1 - 2.6 6.8 23.6 0.95 8.2 5.8 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Med19 PF10278.9 CDJ56519.1 - 3.5 7.5 19.2 0.48 10.3 6.3 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 V_ATPase_I PF01496.19 CDJ56519.1 - 5.4 4.8 33.9 0.56 8.1 6.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ASD2 PF08687.11 CDJ56519.1 - 9.4 5.7 43.0 1.2 8.7 10.9 3.8 4 0 0 4 4 4 0 Apx/Shroom domain ASD2 ALMT PF11744.8 CDJ56519.1 - 9.5 4.9 28.0 4.4 6.0 8.3 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter Histone PF00125.24 CDJ56520.1 - 1.2e-54 184.2 1.4 1.3e-54 184.0 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CDJ56520.1 - 0.00024 21.7 0.9 0.00029 21.4 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CDJ56520.1 - 0.00039 20.5 0.1 0.00072 19.6 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDJ56520.1 - 0.00046 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDJ56520.1 - 0.0065 16.7 0.5 0.01 16.1 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDJ56520.1 - 0.016 15.3 0.1 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF3883 PF13020.6 CDJ56522.1 - 1.6e-11 44.1 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cupin_8 PF13621.6 CDJ56523.1 - 2.9e-22 79.6 0.0 6.6e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain HalX PF08663.10 CDJ56523.1 - 0.036 14.4 10.0 0.045 14.1 8.9 1.7 2 0 0 2 2 2 0 HalX domain Rx_N PF18052.1 CDJ56523.1 - 0.046 14.0 0.4 0.089 13.1 0.4 1.4 1 0 0 1 1 1 0 Rx N-terminal domain LRS4 PF10422.9 CDJ56523.1 - 0.062 12.9 0.7 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 DUF4653 PF15546.6 CDJ56523.1 - 0.11 12.1 1.4 1.5 8.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) UPF0242 PF06785.11 CDJ56523.1 - 0.33 11.1 4.2 0.56 10.3 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4122 PF13498.6 CDJ56523.1 - 0.34 10.6 1.6 0.55 9.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) OmpH PF03938.14 CDJ56523.1 - 0.72 10.2 5.0 1.3 9.4 5.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF842 PF05811.13 CDJ56523.1 - 0.89 9.3 5.7 0.63 9.7 1.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) ABC_tran_CTD PF16326.5 CDJ56523.1 - 1.9 8.8 11.4 3.7 7.9 11.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Rieske PF00355.26 CDJ56524.1 - 1.4e-10 40.9 0.9 2.9e-10 39.9 0.9 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CDJ56524.1 - 0.01 16.3 0.0 0.038 14.5 0.0 2.0 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Ank_4 PF13637.6 CDJ56527.1 - 4.9e-16 58.9 1.0 0.00072 20.1 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ56527.1 - 7.4e-15 55.3 0.0 8.2e-07 29.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ56527.1 - 1e-13 51.2 0.7 0.028 14.7 0.0 5.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ56527.1 - 2.6e-08 34.0 5.1 0.046 14.2 0.0 6.0 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 CDJ56527.1 - 9e-08 31.8 0.8 0.56 10.9 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Fer2_4 PF13510.6 CDJ56527.1 - 0.061 13.4 1.5 2.6 8.1 0.1 3.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain K-box PF01486.17 CDJ56528.1 - 0.016 15.4 0.4 0.069 13.3 0.4 2.1 1 0 0 1 1 1 0 K-box region TMPIT PF07851.13 CDJ56528.1 - 2 7.6 3.9 0.87 8.8 1.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein RabGAP-TBC PF00566.18 CDJ56529.1 - 1.5e-10 41.1 9.9 1.5e-07 31.3 4.3 3.9 6 0 0 6 6 6 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDJ56529.1 - 0.078 13.5 0.0 0.4 11.2 0.0 2.2 2 0 0 2 2 2 0 Rhodanese-like domain rve PF00665.26 CDJ56530.1 - 1.3e-12 48.0 0.1 2.9e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ56530.1 - 3.4e-10 39.7 0.0 7.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CDJ56530.1 - 2.3e-06 27.6 0.4 7e-06 26.0 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDJ56530.1 - 0.03 14.1 0.1 0.092 12.5 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 CDJ56531.1 - 1.1e-22 80.0 0.1 1.9e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ56531.1 - 4.4e-21 75.4 0.0 7.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDJ56531.1 - 1.2e-19 70.5 0.0 2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CDJ56531.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like EELM2 PF15863.5 CDJ56532.1 - 7e-78 260.6 0.1 1.1e-77 260.1 0.1 1.3 1 0 0 1 1 1 1 Extended EGL-27 and MTA1 homology domain PHD PF00628.29 CDJ56532.1 - 3.2e-08 33.3 6.6 3.2e-08 33.3 6.6 1.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ56532.1 - 0.0081 15.8 5.1 0.074 12.7 2.8 2.7 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CDJ56532.1 - 8.2 6.1 9.8 0.5 10.0 4.3 1.9 2 0 0 2 2 2 0 PHD-finger Ribosomal_S17_N PF16205.5 CDJ56533.1 - 2.9e-28 98.0 0.1 5.9e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CDJ56533.1 - 1.3e-23 82.8 1.5 2e-23 82.3 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Nop25 PF09805.9 CDJ56534.1 - 2.8e-12 47.3 9.0 2.8e-12 47.3 9.0 2.2 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Flu_NS2 PF00601.19 CDJ56534.1 - 0.25 11.6 2.2 0.44 10.9 2.2 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Ribosomal_S5 PF00333.20 CDJ56536.1 - 1.6e-29 101.6 0.4 3.1e-29 100.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDJ56536.1 - 1.8e-23 81.7 0.0 3.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CDJ56536.1 - 5.9 7.5 10.1 14 6.3 10.1 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 NPV_P10 PF05531.12 CDJ56538.1 - 0.00099 19.5 0.3 0.0014 19.1 0.3 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein RPW8 PF05659.11 CDJ56538.1 - 0.025 14.3 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.32 CDJ56539.1 - 2.2e-21 75.7 3.4 1e-07 32.5 0.5 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56539.1 - 6.6e-07 29.5 0.0 0.00096 19.4 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ56539.1 - 0.00052 19.1 0.1 0.68 8.8 0.0 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein V-ATPase_G PF03179.15 CDJ56540.1 - 2.9e-24 85.6 8.0 3.8e-24 85.3 8.0 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Peptidase_C98 PF15499.6 CDJ56540.1 - 0.11 11.9 1.2 0.14 11.6 1.2 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ATP-synt_B PF00430.18 CDJ56540.1 - 0.14 12.2 10.2 0.12 12.4 8.9 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) WD40 PF00400.32 CDJ56543.1 - 1.6e-13 50.8 8.5 0.038 14.9 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56543.1 - 0.0011 19.2 0.6 1.1 9.6 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Med25 PF11232.8 CDJ56544.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 WD40_4 PF16300.5 CDJ56545.1 - 5.9e-19 67.7 0.0 1.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDJ56545.1 - 6e-13 49.1 4.3 1.1e-06 29.2 0.0 4.3 4 0 0 4 4 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56545.1 - 1.1e-09 38.4 0.1 0.0033 17.7 0.1 4.1 3 1 1 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 CDJ56545.1 - 1.3e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) MAD PF05557.13 CDJ56545.1 - 0.00078 17.9 17.1 0.0013 17.2 17.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein eIF2A PF08662.11 CDJ56545.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TolA_bind_tri PF16331.5 CDJ56545.1 - 0.0024 17.9 16.4 0.66 10.1 11.2 2.9 2 1 1 3 3 3 2 TolA binding protein trimerisation BLOC1_2 PF10046.9 CDJ56545.1 - 0.0026 18.0 19.4 0.21 11.9 8.4 2.4 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 CDJ56545.1 - 0.0044 16.6 8.1 0.0065 16.1 8.1 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4795 PF16043.5 CDJ56545.1 - 0.022 14.4 16.6 0.033 13.8 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF724 PF05266.14 CDJ56545.1 - 0.042 13.7 17.6 0.086 12.7 17.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 CDJ56545.1 - 0.095 12.7 8.5 0.082 13.0 3.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 CDJ56545.1 - 0.1 12.3 8.4 0.15 11.8 2.5 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tropomyosin_1 PF12718.7 CDJ56545.1 - 0.11 12.7 30.6 0.46 10.6 30.5 1.8 1 1 1 2 2 2 0 Tropomyosin like DUF3584 PF12128.8 CDJ56545.1 - 0.11 10.0 18.7 0.15 9.6 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MRF_C1 PF13887.6 CDJ56545.1 - 0.22 10.7 1.3 22 4.3 0.0 3.1 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 Lebercilin PF15619.6 CDJ56545.1 - 0.24 11.1 29.0 3.1 7.4 14.1 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 CDJ56545.1 - 0.31 10.5 27.9 0.9 9.0 27.8 1.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ABC_tran_CTD PF16326.5 CDJ56545.1 - 0.35 11.1 26.7 0.37 11.1 7.8 4.0 1 1 4 5 5 5 0 ABC transporter C-terminal domain FliD_C PF07195.12 CDJ56545.1 - 0.38 10.1 9.4 3.3 7.1 5.0 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CENP-F_leu_zip PF10473.9 CDJ56545.1 - 0.53 10.3 26.5 1.1 9.3 26.4 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 CDJ56545.1 - 0.72 8.9 19.3 1.1 8.3 19.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vpu PF00558.19 CDJ56545.1 - 0.82 9.5 7.0 2.7 7.8 7.0 1.9 1 1 0 1 1 1 0 Vpu protein DUF4407 PF14362.6 CDJ56545.1 - 0.99 8.7 15.6 1.6 8.0 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Leu_zip PF15294.6 CDJ56545.1 - 1 8.8 22.7 5.4 6.4 22.5 1.9 1 1 1 2 2 2 0 Leucine zipper Jnk-SapK_ap_N PF09744.9 CDJ56545.1 - 1.7 8.8 28.2 8.5 6.6 11.1 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 CDJ56545.1 - 2.2 7.6 28.6 0.66 9.3 11.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Med4 PF10018.9 CDJ56545.1 - 2.5 7.7 19.9 0.32 10.7 2.9 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF812 PF05667.11 CDJ56545.1 - 4.1 6.2 25.4 18 4.0 25.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HlyD_2 PF12700.7 CDJ56545.1 - 5.6 5.6 10.8 8.3 5.0 10.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Fmp27_WPPW PF10359.9 CDJ56545.1 - 6.7 5.4 13.6 11 4.7 13.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Shugoshin_N PF07558.11 CDJ56545.1 - 7.2 6.6 11.0 0.57 10.1 0.7 3.4 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Fez1 PF06818.15 CDJ56545.1 - 9.8 6.6 24.5 22 5.4 24.5 1.5 1 1 0 1 1 1 0 Fez1 YebG PF07130.12 CDJ56546.1 - 0.008 16.0 0.3 0.023 14.5 0.3 1.7 1 0 0 1 1 1 1 YebG protein PRP1_N PF06424.12 CDJ56547.1 - 9.2e-51 172.1 6.4 2.8e-42 144.6 3.9 2.8 2 1 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDJ56547.1 - 1.9e-27 93.6 32.4 0.0026 18.4 0.2 14.6 7 3 9 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56547.1 - 7.6e-19 68.0 14.2 0.00096 19.6 0.3 9.0 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ56547.1 - 2.5e-07 30.4 1.9 1.8 9.0 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56547.1 - 3.4e-07 30.8 14.2 0.00086 19.9 0.0 8.2 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ56547.1 - 1.1e-06 28.3 13.2 5.8 7.3 0.0 10.1 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ56547.1 - 9.5e-05 22.5 7.2 0.39 11.2 0.0 8.6 13 2 1 14 14 9 1 Tetratricopeptide repeat ChAPs PF09295.10 CDJ56547.1 - 0.00017 20.7 7.8 0.034 13.1 0.1 4.1 2 1 0 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.6 CDJ56547.1 - 0.00033 20.3 0.0 4.5 7.0 0.0 4.9 5 0 0 5 5 5 1 TPR repeat TPR_12 PF13424.6 CDJ56547.1 - 0.00047 20.4 9.5 1.3 9.3 0.1 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ56547.1 - 0.00095 19.3 6.6 0.48 10.7 0.2 5.1 4 2 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 CDJ56547.1 - 0.0015 18.5 0.0 7.8 6.4 0.1 4.7 3 3 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_9 PF13371.6 CDJ56547.1 - 0.0046 17.1 7.4 0.45 10.7 0.2 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 CDJ56547.1 - 0.0085 14.9 2.8 0.66 8.7 0.1 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 CDJ56547.1 - 0.036 13.8 16.1 0.029 14.1 5.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain HHH PF00633.23 CDJ56547.1 - 0.074 13.0 0.0 0.45 10.5 0.0 2.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif SCAN PF02023.17 CDJ56547.1 - 0.36 10.7 4.4 3.9 7.3 0.1 3.9 2 1 1 3 3 3 0 SCAN domain Tho2 PF11262.8 CDJ56547.1 - 1.8 7.7 4.3 1.4 8.0 1.4 2.2 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 TPR_6 PF13174.6 CDJ56547.1 - 2.5 8.9 17.9 31 5.5 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 CDJ56548.1 - 1.1e-36 127.2 0.3 4.1e-26 92.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ56548.1 - 7.4e-13 48.5 0.5 2.7e-12 46.7 0.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ56548.1 - 4.3e-06 26.6 0.1 1.8e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ56548.1 - 4.3e-06 26.1 3.8 8.2e-06 25.2 3.8 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDJ56548.1 - 7.1e-06 25.5 0.2 1.4e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ56548.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ56548.1 - 8.2e-05 21.9 0.2 0.0013 18.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 CDJ56548.1 - 0.00012 21.4 0.2 0.00025 20.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CDJ56548.1 - 0.001 19.6 0.2 0.0029 18.1 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ56548.1 - 0.0051 15.6 0.8 0.0051 15.6 0.8 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 CDJ56548.1 - 0.0069 15.5 2.1 0.013 14.6 2.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CDJ56548.1 - 0.0074 15.6 2.3 0.017 14.4 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain PHD PF00628.29 CDJ56548.1 - 0.041 13.8 5.5 0.02 14.8 0.8 2.8 2 0 0 2 2 2 0 PHD-finger MCRA PF06100.11 CDJ56548.1 - 0.11 11.3 0.8 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 MCRA family zf-RING_2 PF13639.6 CDJ56548.1 - 1.5 9.2 9.8 0.13 12.6 3.8 2.6 2 0 0 2 2 2 0 Ring finger domain Ephrin_rec_like PF07699.13 CDJ56549.1 - 1.9e-29 101.1 115.1 1.4e-08 34.4 3.6 11.9 12 0 0 12 12 12 8 Putative ephrin-receptor like PAN_4 PF14295.6 CDJ56549.1 - 0.0024 17.7 0.7 0.018 14.9 0.7 2.6 1 0 0 1 1 1 1 PAN domain AAA_13 PF13166.6 CDJ56549.1 - 0.032 12.9 1.5 0.045 12.4 1.5 1.1 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 CDJ56549.1 - 0.053 13.8 0.9 0.12 12.6 0.9 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Arylesterase PF01731.20 CDJ56549.1 - 0.16 12.2 0.0 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 Arylesterase He_PIG PF05345.12 CDJ56549.1 - 0.17 12.1 1.5 0.63 10.3 0.3 2.5 2 0 0 2 2 2 0 Putative Ig domain Uso1_p115_C PF04871.13 CDJ56549.1 - 0.73 10.2 6.2 2 8.8 6.2 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 CDJ56549.1 - 1.9 9.1 9.2 14 6.4 6.3 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DNA_pol_B PF00136.21 CDJ56550.1 - 4.5e-96 322.4 0.1 6.9e-96 321.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDJ56550.1 - 3.6e-61 207.2 0.0 6.7e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CDJ56550.1 - 0.018 13.9 0.6 0.072 11.9 0.1 1.9 1 1 1 2 2 2 0 DNA polymerase type B, organellar and viral Pkinase PF00069.25 CDJ56551.1 - 8.8e-12 44.9 0.0 8.8e-12 44.9 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56551.1 - 6e-07 29.0 0.0 2.5e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 Protein tyrosine kinase RskA PF10099.9 CDJ56551.1 - 0.00062 20.1 6.8 0.00062 20.1 6.8 20.6 10 7 6 18 18 18 4 Anti-sigma-K factor rskA CPSF_A PF03178.15 CDJ56553.1 - 4.5e-22 78.8 1.3 6.5e-13 48.7 0.0 3.5 3 0 0 3 3 3 3 CPSF A subunit region MMS1_N PF10433.9 CDJ56553.1 - 1.2e-21 77.0 0.0 3.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SR-25 PF10500.9 CDJ56553.1 - 6.1e-05 22.7 34.4 0.00017 21.3 17.4 19.3 14 5 3 17 17 17 4 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ56553.1 - 0.00048 20.5 2.8 0.00048 20.5 2.8 15.3 11 3 1 13 13 13 4 Anti-sigma-K factor rskA Syja_N PF02383.18 CDJ56554.1 - 2.2e-08 33.8 11.5 2.2e-08 33.8 11.5 3.9 2 1 1 3 3 3 1 SacI homology domain CNDH2_C PF16858.5 CDJ56554.1 - 0.0058 16.6 12.7 0.0058 16.6 12.7 2.4 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 CDJ56554.1 - 0.39 9.5 23.7 0.38 9.5 9.8 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Isy1 PF06246.12 CDJ56554.1 - 1.8 8.1 35.4 0.32 10.5 14.5 2.6 2 0 0 2 2 2 0 Isy1-like splicing family SID-1_RNA_chan PF13965.6 CDJ56554.1 - 3.5 5.9 15.5 1.7 7.0 1.7 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ABC_membrane_3 PF13748.6 CDJ56554.1 - 4.1 6.6 4.1 1.1 8.4 0.2 2.1 2 0 0 2 2 2 0 ABC transporter transmembrane region Slu7 PF11708.8 CDJ56554.1 - 9.3 5.9 45.5 0.034 13.9 15.6 3.1 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor Shadoo PF14999.6 CDJ56557.1 - 0.013 15.6 3.5 0.013 15.6 3.5 3.9 2 1 1 3 3 1 0 Shadow of prion protein, neuroprotective EPL1 PF10513.9 CDJ56557.1 - 0.013 15.8 0.6 0.013 15.8 0.6 3.1 2 1 0 2 2 1 0 Enhancer of polycomb-like CNDH2_C PF16858.5 CDJ56557.1 - 0.075 12.9 19.3 0.23 11.3 1.7 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RCC1 PF00415.18 CDJ56557.1 - 0.094 13.4 0.2 4.9 7.9 0.0 3.4 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat NST1 PF13945.6 CDJ56557.1 - 0.11 12.5 31.6 0.43 10.7 9.6 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator RCC1_2 PF13540.6 CDJ56557.1 - 0.2 11.5 0.9 0.45 10.4 0.3 2.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat MAT1 PF06391.13 CDJ56557.1 - 0.21 11.4 27.6 0.84 9.4 13.8 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF572 PF04502.13 CDJ56557.1 - 0.52 9.9 24.4 0.35 10.4 11.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3402 PF11882.8 CDJ56557.1 - 0.91 8.6 15.2 2.1 7.3 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Band_3_cyto PF07565.13 CDJ56557.1 - 1 9.1 17.0 2.8 7.7 2.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Lin-8 PF03353.15 CDJ56557.1 - 1.5 8.3 27.4 0.36 10.3 2.5 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist OATP PF03137.20 CDJ56557.1 - 2.2 6.5 6.9 1.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2052 PF09747.9 CDJ56557.1 - 2.8 8.0 34.3 0.49 10.5 8.3 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.10 CDJ56557.1 - 2.8 6.5 32.7 0.12 11.0 2.5 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ56557.1 - 3.3 6.5 20.1 4.6 6.0 1.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4638 PF15472.6 CDJ56557.1 - 3.9 7.1 19.1 0.34 10.6 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) SLC12 PF03522.15 CDJ56557.1 - 5 6.0 22.7 2 7.4 3.5 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Slu7 PF11708.8 CDJ56557.1 - 6.8 6.4 33.5 0.88 9.3 10.4 2.7 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor PHO4 PF01384.20 CDJ56558.1 - 7.8e-44 150.1 1.2 1.4e-43 149.2 1.2 1.3 1 1 0 1 1 1 1 Phosphate transporter family DUF2722 PF10846.8 CDJ56558.1 - 0.0019 17.2 2.2 0.0019 17.2 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ56558.1 - 0.0024 18.6 0.6 0.0027 18.4 0.6 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2681 PF10883.8 CDJ56558.1 - 0.0034 17.8 9.0 0.0057 17.0 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Ureide_permease PF07168.11 CDJ56558.1 - 0.018 13.8 0.5 0.018 13.8 0.5 1.5 2 0 0 2 2 2 0 Ureide permease FPN1 PF06963.12 CDJ56558.1 - 0.072 11.6 0.3 0.12 11.0 0.3 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3808 PF10300.9 CDJ56558.1 - 0.072 11.8 1.7 0.093 11.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) DUF4834 PF16118.5 CDJ56558.1 - 0.31 12.0 3.6 0.58 11.1 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ56558.1 - 0.54 10.2 14.8 0.65 9.9 14.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ56558.1 - 0.76 9.3 17.1 0.96 9.0 17.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF2232 PF09991.9 CDJ56558.1 - 0.93 8.6 8.7 0.13 11.5 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF2967 PF11179.8 CDJ56558.1 - 2.8 5.9 8.7 3.7 5.5 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Med3 PF11593.8 CDJ56558.1 - 9.2 5.3 13.7 13 4.9 13.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal COX1 PF00115.20 CDJ56559.1 - 2.2e-72 244.3 50.7 2.6e-68 230.9 34.8 2.8 2 1 1 3 3 3 2 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_B PF00033.19 CDJ56559.1 - 1.2e-16 61.1 6.0 1.2e-16 61.1 6.0 3.9 2 1 2 4 4 4 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 CDJ56559.1 - 4.7e-13 49.5 1.2 4.7e-13 49.5 1.2 3.3 3 2 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 CDJ56559.1 - 8.4e-10 38.9 1.0 8.4e-10 38.9 1.0 3.9 3 1 2 5 5 5 1 Cytochrome b(C-terminal)/b6/petD TMEM237 PF15383.6 CDJ56559.1 - 1.5 7.8 5.8 0.33 10.0 0.5 2.4 3 0 0 3 3 3 0 Transmembrane protein 237 DUF3789 PF12664.7 CDJ56559.1 - 1.7 8.4 8.5 0.61 9.8 3.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) GatB_N PF02934.15 CDJ56560.1 - 4.4e-14 52.5 0.6 2.9e-06 26.9 0.1 2.5 1 1 1 2 2 2 2 GatB/GatE catalytic domain Presenilin PF01080.17 CDJ56560.1 - 0.0056 15.5 2.3 0.0056 15.5 2.3 1.6 2 0 0 2 2 2 1 Presenilin zf-Tim10_DDP PF02953.15 CDJ56560.1 - 0.27 10.9 6.1 8.2 6.2 0.1 2.7 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF5563 PF17718.1 CDJ56560.1 - 2 7.9 5.6 0.49 9.9 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5563) DUF1180 PF06679.12 CDJ56560.1 - 3.7 7.9 19.7 1.5 9.2 7.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1180) Senescence_reg PF04520.13 CDJ56560.1 - 8 7.3 11.0 6.1 7.7 5.2 2.3 2 0 0 2 2 2 0 Senescence regulator Secretin_N_2 PF07655.13 CDJ56560.1 - 8.4 7.0 28.7 0.4 11.3 6.6 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain SPX PF03105.19 CDJ56561.1 - 4.6e-05 23.5 0.9 4.6e-05 23.5 0.9 2.3 1 1 1 2 2 2 1 SPX domain DUF4667 PF15700.5 CDJ56561.1 - 0.00031 20.9 2.1 0.00031 20.9 2.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) Sporozoite_P67 PF05642.11 CDJ56561.1 - 0.034 12.3 0.0 0.034 12.3 0.0 2.7 1 1 2 3 3 3 0 Sporozoite P67 surface antigen DUF4131 PF13567.6 CDJ56561.1 - 0.059 13.0 0.6 0.2 11.3 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2142 PF09913.9 CDJ56561.1 - 0.061 12.2 0.3 0.13 11.1 0.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) EBP50_C PF09007.11 CDJ56561.1 - 1.3 10.1 27.2 1.3 10.0 9.7 3.4 3 0 0 3 3 3 0 EBP50, C-terminal Apt1 PF10351.9 CDJ56561.1 - 1.5 7.6 22.7 0.62 8.8 7.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 CDJ56561.1 - 2.1 8.3 10.2 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Isy1 PF06246.12 CDJ56561.1 - 3.9 7.0 10.2 7.3 6.1 7.2 2.1 2 0 0 2 2 2 0 Isy1-like splicing family Activator_LAG-3 PF11498.8 CDJ56562.1 - 0.00087 18.4 27.6 0.00087 18.4 27.6 9.1 5 2 3 8 8 8 1 Transcriptional activator LAG-3 DUF4746 PF15928.5 CDJ56562.1 - 2.3 7.5 0.0 2.3 7.5 0.0 6.8 3 1 3 6 6 6 0 Domain of unknown function (DUF4746) tRNA-synt_1b PF00579.25 CDJ56563.1 - 6.4e-21 74.9 3.8 2.4e-10 40.3 2.6 3.4 2 1 1 3 3 3 2 tRNA synthetases class I (W and Y) S4 PF01479.25 CDJ56563.1 - 7.7e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 CDJ56563.1 - 0.00098 18.9 0.1 0.0095 15.7 0.0 2.4 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain PRCC PF10253.9 CDJ56563.1 - 0.01 16.6 24.1 0.58 10.9 1.4 4.6 4 1 0 4 4 4 0 Mitotic checkpoint regulator, MAD2B-interacting Presenilin PF01080.17 CDJ56563.1 - 0.033 13.0 18.2 0.01 14.7 7.7 2.6 2 0 0 2 2 2 0 Presenilin Solute_trans_a PF03619.16 CDJ56564.1 - 4.1e-22 79.0 1.5 1.6e-07 31.1 0.0 3.1 2 1 1 3 3 3 3 Organic solute transporter Ostalpha Ion_trans_2 PF07885.16 CDJ56565.1 - 0.076 13.0 0.4 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Ion channel Zip PF02535.22 CDJ56565.1 - 6.3 5.9 11.1 9.3 5.4 4.8 2.8 2 0 0 2 2 2 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ56567.1 - 0.00024 21.1 5.4 0.00024 21.1 5.4 8.3 4 3 2 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 CDJ56567.1 - 0.0054 17.1 1.2 0.0054 17.1 1.2 5.0 1 1 1 3 3 3 1 Enhancer of polycomb-like CDC27 PF09507.10 CDJ56567.1 - 3.6 6.9 58.2 0.13 11.6 27.8 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Spt20 PF12090.8 CDJ56569.1 - 0.68 9.5 27.5 0.27 10.8 0.8 2.3 2 0 0 2 2 2 0 Spt20 family Exonuc_VII_L PF02601.15 CDJ56569.1 - 0.68 9.4 8.2 3.5 7.1 7.1 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit Macoilin PF09726.9 CDJ56569.1 - 5.4 5.4 14.2 12 4.2 14.2 1.6 1 0 0 1 1 1 0 Macoilin family Activator_LAG-3 PF11498.8 CDJ56569.1 - 8 5.3 35.9 5.7 5.8 10.5 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 zf-CCCH PF00642.24 CDJ56570.1 - 2.3e-07 30.6 18.0 4.5e-05 23.3 1.5 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ56570.1 - 3e-06 27.1 14.6 0.026 14.6 0.7 3.7 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 CDJ56570.1 - 0.00031 21.4 5.8 0.5 11.1 0.0 2.9 2 1 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CDJ56570.1 - 0.013 15.3 1.0 0.013 15.3 1.0 3.8 3 1 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDJ56570.1 - 0.52 10.6 9.8 0.2 11.9 4.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family BT1 PF03092.16 CDJ56571.1 - 8.3e-79 265.2 25.1 8.8e-54 182.6 12.8 2.1 2 0 0 2 2 2 2 BT1 family SR-25 PF10500.9 CDJ56572.1 - 0.0089 15.7 5.6 0.0089 15.7 5.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.9 CDJ56572.1 - 0.19 10.8 3.9 0.29 10.2 3.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LRR_4 PF12799.7 CDJ56573.1 - 0.0085 16.5 3.5 18 5.9 0.0 4.7 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF668 PF05003.12 CDJ56574.1 - 0.14 12.7 2.2 2.5 8.6 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF668) DNA_pol3_alpha PF07733.12 CDJ56574.1 - 0.47 10.0 4.7 0.13 11.8 0.6 2.2 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain HTH_38 PF13936.6 CDJ56575.1 - 4.3e-06 26.4 2.7 1.2e-05 24.9 2.7 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDJ56575.1 - 8.4e-06 25.4 1.2 8.4e-06 25.4 1.2 2.4 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CDJ56575.1 - 0.00014 21.5 0.3 0.00032 20.3 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_Tc3_1 PF11427.8 CDJ56575.1 - 0.0052 16.6 2.2 0.0052 16.6 2.2 1.9 2 0 0 2 2 2 1 Tc3 transposase HTH_29 PF13551.6 CDJ56575.1 - 0.031 14.3 0.3 0.074 13.1 0.3 1.7 1 0 0 1 1 1 0 Winged helix-turn helix EPL1 PF10513.9 CDJ56577.1 - 0.0024 18.3 0.6 0.0027 18.1 0.6 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like SpoIIP PF07454.11 CDJ56577.1 - 0.011 15.2 1.9 0.013 15.0 1.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4175 PF13779.6 CDJ56577.1 - 0.034 12.1 14.6 0.041 11.8 14.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.13 CDJ56577.1 - 0.046 14.4 14.3 0.058 14.0 14.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ56577.1 - 0.15 12.0 23.5 0.2 11.7 23.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ56577.1 - 0.21 11.3 3.2 0.25 11.1 3.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ndc1_Nup PF09531.10 CDJ56577.1 - 0.23 10.1 3.7 0.25 10.0 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CDJ56577.1 - 0.4 9.4 6.4 0.5 9.1 6.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asparaginase_2 PF01112.18 CDJ56577.1 - 0.4 9.6 2.9 0.54 9.2 2.9 1.1 1 0 0 1 1 1 0 Asparaginase TERB2 PF15101.6 CDJ56577.1 - 0.55 10.3 10.6 0.69 9.9 10.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Androgen_recep PF02166.16 CDJ56577.1 - 0.6 8.9 20.3 0.79 8.5 20.3 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ56577.1 - 0.83 9.2 32.5 1.1 8.9 31.7 1.5 2 0 0 2 2 2 0 Spt20 family Spore_coat_CotO PF14153.6 CDJ56577.1 - 0.88 9.5 15.2 1.2 9.1 15.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.14 CDJ56577.1 - 1.2 9.0 13.2 1.5 8.7 13.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 CDJ56577.1 - 1.5 7.7 26.5 2.4 7.0 26.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PDEase_I PF00233.19 CDJ56577.1 - 1.6 8.4 6.4 0.33 10.6 0.6 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase CCDC53 PF10152.9 CDJ56577.1 - 3.5 8.0 11.7 5 7.5 11.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex UPF0560 PF10577.9 CDJ56577.1 - 4.7 5.6 13.1 6.1 5.2 13.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Plasmodium_Vir PF05795.11 CDJ56577.1 - 9.5 5.5 5.9 12 5.2 5.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CRM1_C PF08767.11 CDJ56578.1 - 1.8e-80 270.5 4.6 7.1e-80 268.6 4.6 1.8 1 1 0 1 1 1 1 CRM1 C terminal AF0941-like PF14591.6 CDJ56578.1 - 0.03 14.9 0.0 0.14 12.7 0.0 2.2 1 1 0 1 1 1 0 AF0941-like HECT PF00632.25 CDJ56579.1 - 6.1e-33 114.6 1.0 2.1e-21 76.7 0.2 2.1 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Spt20 PF12090.8 CDJ56579.1 - 1.9e-05 24.4 9.2 2.5e-05 24.0 9.2 1.2 1 0 0 1 1 1 1 Spt20 family SPX PF03105.19 CDJ56579.1 - 8.6e-05 22.6 10.0 9.7e-05 22.4 10.0 1.1 1 0 0 1 1 1 1 SPX domain Macoilin PF09726.9 CDJ56579.1 - 0.00026 19.7 14.8 0.00032 19.4 14.8 1.1 1 0 0 1 1 1 1 Macoilin family Apt1 PF10351.9 CDJ56579.1 - 0.00046 19.2 11.0 0.00057 18.9 11.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Menin PF05053.13 CDJ56579.1 - 0.00046 18.7 6.1 0.0006 18.3 6.1 1.1 1 0 0 1 1 1 1 Menin Plasmodium_Vir PF05795.11 CDJ56579.1 - 0.0028 17.1 7.8 0.0037 16.7 7.8 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein RAP1 PF07218.11 CDJ56579.1 - 0.0041 15.5 12.2 0.0046 15.3 12.2 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Presenilin PF01080.17 CDJ56579.1 - 0.006 15.4 10.1 0.0078 15.0 10.1 1.1 1 0 0 1 1 1 1 Presenilin SOG2 PF10428.9 CDJ56579.1 - 0.0069 15.6 14.7 0.0088 15.3 14.7 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Hid1 PF12722.7 CDJ56579.1 - 0.012 13.8 7.2 0.015 13.5 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 CDJ56579.1 - 0.048 12.5 4.7 0.057 12.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nop14 PF04147.12 CDJ56579.1 - 0.05 11.8 4.3 0.056 11.7 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CDJ56579.1 - 0.06 12.1 3.8 0.084 11.6 3.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Miga PF10265.9 CDJ56579.1 - 0.071 12.1 7.6 0.086 11.8 7.6 1.1 1 0 0 1 1 1 0 Mitoguardin Lin-8 PF03353.15 CDJ56579.1 - 0.072 12.6 14.4 0.12 11.9 14.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 CDJ56579.1 - 0.073 11.9 7.8 0.099 11.4 7.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CDJ56579.1 - 0.14 11.1 8.2 0.18 10.8 8.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Roughex PF06020.11 CDJ56579.1 - 0.14 11.2 7.9 0.2 10.7 7.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF572 PF04502.13 CDJ56579.1 - 0.2 11.2 9.2 0.28 10.8 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zip PF02535.22 CDJ56579.1 - 0.22 10.7 2.0 0.26 10.5 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 CDJ56579.1 - 0.33 8.0 14.2 0.42 7.7 14.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CDJ56579.1 - 0.36 10.8 16.5 0.49 10.3 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ56579.1 - 0.37 10.8 7.2 0.58 10.1 7.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tmemb_cc2 PF10267.9 CDJ56579.1 - 0.46 9.6 10.4 0.62 9.1 10.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Med3 PF11593.8 CDJ56579.1 - 0.6 9.2 17.5 0.94 8.6 17.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Smg8_Smg9 PF10220.9 CDJ56579.1 - 0.71 8.1 15.0 1 7.6 15.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 NST1 PF13945.6 CDJ56579.1 - 0.75 9.9 16.5 1.4 9.0 16.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_S64 PF08192.11 CDJ56579.1 - 1.9 6.9 17.7 2.5 6.5 17.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 CDJ56579.1 - 2.6 7.9 7.6 4.2 7.3 7.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LAP1C PF05609.12 CDJ56579.1 - 3.7 6.5 15.7 5.1 6.1 15.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.12 CDJ56579.1 - 4 7.1 16.2 5.8 6.6 16.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF908 PF06012.12 CDJ56579.1 - 4.2 6.7 16.8 6.1 6.1 16.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) R_equi_Vir PF05526.11 CDJ56579.1 - 4.7 7.0 14.8 0.056 13.3 1.6 2.2 1 1 1 2 2 2 0 Rhodococcus equi virulence-associated protein PNISR PF15996.5 CDJ56579.1 - 5.2 7.3 16.9 8.5 6.6 16.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Utp14 PF04615.13 CDJ56579.1 - 5.2 5.5 18.0 6.9 5.1 18.0 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 CDJ56579.1 - 6.7 5.3 14.5 8.9 4.9 14.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RimM PF01782.18 CDJ56580.1 - 3e-05 24.1 0.0 7.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 CDJ56580.1 - 0.041 14.0 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PRC-barrel domain HypA PF01155.19 CDJ56580.1 - 0.046 13.8 0.4 0.1 12.6 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S25 PF03297.15 CDJ56581.1 - 2.1e-36 124.2 2.4 2.7e-36 123.8 2.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Mt_ATP-synt_D PF05873.12 CDJ56581.1 - 0.032 14.1 0.5 0.042 13.7 0.5 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) MarR_2 PF12802.7 CDJ56581.1 - 0.037 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 MarR family DEAD PF00270.29 CDJ56582.1 - 2.2e-31 109.0 0.8 6.2e-31 107.5 0.2 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ56582.1 - 1.8e-19 70.1 0.0 5.2e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ56582.1 - 0.001 19.1 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ56582.1 - 0.003 17.8 0.1 0.015 15.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain SIS PF01380.22 CDJ56582.1 - 0.029 14.2 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 SIS domain Phage_integrase PF00589.22 CDJ56583.1 - 1.6e-17 63.8 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family SAP PF02037.27 CDJ56583.1 - 9.8e-05 22.0 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain DZR PF12773.7 CDJ56583.1 - 0.0076 16.2 3.2 0.17 11.9 0.3 2.4 1 1 1 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CDJ56583.1 - 0.71 9.7 3.4 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SUIM_assoc PF16619.5 CDJ56585.1 - 0.00033 20.7 4.1 0.0011 19.0 4.1 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 UQ_con PF00179.26 CDJ56585.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1917 PF08939.10 CDJ56585.1 - 0.007 16.3 0.4 0.016 15.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TFIIA PF03153.13 CDJ56585.1 - 0.031 14.3 14.4 0.047 13.7 14.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ56585.1 - 0.16 11.0 6.1 0.3 10.1 6.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 CDJ56585.1 - 5.9 5.3 13.9 4.2 5.8 5.2 2.1 2 0 0 2 2 2 0 Macoilin family RAB3GAP2_N PF14655.6 CDJ56585.1 - 6.6 5.9 7.3 38 3.4 4.9 2.2 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 CDJ56585.1 - 9.6 5.7 20.3 0.2 11.3 13.6 1.5 2 0 0 2 2 2 0 Spt20 family DUF1323 PF07037.11 CDJ56587.1 - 9.6 6.6 15.3 0.79 10.1 8.0 2.2 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) Secretin_N_2 PF07655.13 CDJ56588.1 - 0.33 11.5 22.3 0.39 11.3 22.3 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 CDJ56588.1 - 2.8 6.4 15.1 2.9 6.3 15.1 1.0 1 0 0 1 1 1 0 Macoilin family Pheromone PF08015.11 CDJ56588.1 - 2.9 9.0 14.3 3.6 8.7 14.3 1.3 1 0 0 1 1 1 0 Fungal mating-type pheromone NAM-associated PF14303.6 CDJ56588.1 - 4.5 8.0 9.3 5.1 7.8 9.3 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4667 PF15700.5 CDJ56588.1 - 10 6.2 19.8 12 5.9 19.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) bZIP_2 PF07716.15 CDJ56589.1 - 0.078 13.1 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper AAA PF00004.29 CDJ56591.1 - 3.8e-47 160.0 0.1 8.9e-39 132.9 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ56591.1 - 1.1e-10 42.2 1.0 0.00028 21.3 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CDJ56591.1 - 1.7e-09 37.8 0.1 0.00072 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CDJ56591.1 - 2.5e-09 36.8 0.4 7.2e-09 35.3 0.4 1.9 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CDJ56591.1 - 3.2e-08 33.2 0.0 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 CDJ56591.1 - 2.4e-07 30.6 0.0 0.026 14.3 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ56591.1 - 4.9e-07 30.1 0.3 0.0042 17.4 0.2 3.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ56591.1 - 6.8e-07 28.9 0.1 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ56591.1 - 7.9e-07 29.7 0.0 0.03 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CDJ56591.1 - 2.1e-06 28.0 0.0 0.057 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CDJ56591.1 - 2.6e-06 27.5 0.2 0.026 14.4 0.0 3.1 2 1 0 2 2 2 2 NACHT domain AAA_2 PF07724.14 CDJ56591.1 - 4.7e-06 26.8 0.0 0.00034 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 CDJ56591.1 - 1.2e-05 25.0 0.4 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TsaE PF02367.17 CDJ56591.1 - 1.2e-05 25.3 0.1 0.054 13.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDJ56591.1 - 3.9e-05 23.5 0.0 0.036 13.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 CDJ56591.1 - 4.8e-05 23.2 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDJ56591.1 - 0.00013 21.8 0.1 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CDJ56591.1 - 0.00017 21.0 0.1 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 CDJ56591.1 - 0.00017 21.1 0.0 0.031 13.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2075 PF09848.9 CDJ56591.1 - 0.00017 20.9 0.1 0.47 9.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CDJ56591.1 - 0.00031 21.1 0.0 0.078 13.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 CDJ56591.1 - 0.00041 20.1 0.0 0.09 12.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDJ56591.1 - 0.00056 19.7 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 CDJ56591.1 - 0.00056 20.3 0.1 0.57 10.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CDJ56591.1 - 0.00074 18.8 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 CDJ56591.1 - 0.00087 19.6 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CDJ56591.1 - 0.0018 18.8 0.4 0.056 13.9 0.1 2.4 2 0 0 2 2 2 1 ABC transporter KTI12 PF08433.10 CDJ56591.1 - 0.0025 17.3 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_11 PF13086.6 CDJ56591.1 - 0.0025 17.7 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CDJ56591.1 - 0.0025 18.2 0.1 1.3 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDJ56591.1 - 0.0082 16.2 0.0 2.9 7.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CDJ56591.1 - 0.012 15.2 0.9 2.1 7.9 0.1 2.9 2 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CDJ56591.1 - 0.012 14.9 0.3 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 CDJ56591.1 - 0.014 14.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 CDJ56591.1 - 0.018 15.1 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ56591.1 - 0.023 14.6 0.2 1.5 8.6 0.2 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CDJ56591.1 - 0.03 14.3 0.1 8.5 6.3 0.0 2.6 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.17 CDJ56591.1 - 0.039 13.0 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 CDJ56591.1 - 0.071 13.0 0.0 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase CPT PF07931.12 CDJ56591.1 - 0.099 12.5 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.10 CDJ56591.1 - 0.1 12.6 0.1 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 CDJ56591.1 - 0.12 12.2 0.1 3.2 7.6 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain CDC48_N PF02359.18 CDJ56591.1 - 0.13 12.5 0.0 1.8 8.8 0.0 2.9 2 1 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Viral_helicase1 PF01443.18 CDJ56591.1 - 0.15 11.8 0.0 1.4 8.6 0.0 2.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CDJ56591.1 - 0.21 11.2 0.5 4.9 6.7 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4201 PF13870.6 CDJ56592.1 - 1.8e-16 60.4 21.7 1.8e-16 60.4 21.7 4.2 3 2 0 4 4 4 1 Domain of unknown function (DUF4201) Ank_2 PF12796.7 CDJ56592.1 - 0.00043 20.8 0.0 0.0052 17.3 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 CDJ56593.1 - 1.1e-28 99.6 3.3 1e-09 38.8 1.8 5.2 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ56593.1 - 3.8e-25 87.6 9.3 4.5e-09 36.4 0.1 5.6 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDJ56593.1 - 1.9e-24 84.9 12.2 0.00022 21.5 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 CDJ56593.1 - 7.2e-24 83.8 5.1 1.6e-09 38.1 0.2 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ56593.1 - 2.3e-17 61.3 5.8 0.096 13.3 0.1 7.7 7 0 0 7 7 7 5 Ankyrin repeat Sushi PF00084.20 CDJ56593.1 - 3.3e-08 34.0 0.2 6.4e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF5016 PF16408.5 CDJ56594.1 - 0.025 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5016) DnaJ PF00226.31 CDJ56596.1 - 8.8e-20 70.6 0.4 1.7e-19 69.7 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CDJ56596.1 - 3.7e-19 68.9 0.0 6.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain BTB PF00651.31 CDJ56597.1 - 0.0024 18.1 0.2 0.04 14.1 0.2 2.4 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_L27 PF01016.19 CDJ56599.1 - 1.8e-11 43.9 0.2 7.2e-11 42.0 0.2 1.8 1 1 0 1 1 1 1 Ribosomal L27 protein SHR-BD PF06650.12 CDJ56600.1 - 1.4e-05 24.6 0.0 0.0043 16.5 0.0 4.0 3 1 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 AAA PF00004.29 CDJ56601.1 - 2.1e-08 34.7 0.2 1.4e-07 32.0 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Lin-8 PF03353.15 CDJ56601.1 - 0.00017 21.3 4.6 0.00017 21.3 4.6 2.1 2 0 0 2 2 2 1 Ras-mediated vulval-induction antagonist AAA_16 PF13191.6 CDJ56601.1 - 0.0003 21.2 0.0 0.0003 21.2 0.0 3.8 1 1 1 2 2 1 1 AAA ATPase domain Med15 PF09606.10 CDJ56601.1 - 0.0026 16.6 28.6 0.058 12.1 4.0 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Zeta_toxin PF06414.12 CDJ56601.1 - 0.0044 16.3 0.0 0.0044 16.3 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin MAGE_N PF12440.8 CDJ56601.1 - 0.0061 17.2 11.1 0.0061 17.2 11.1 5.3 3 3 1 4 4 2 1 Melanoma associated antigen family N terminal DUF4667 PF15700.5 CDJ56601.1 - 0.0067 16.6 9.0 0.0067 16.6 9.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) AAA_5 PF07728.14 CDJ56601.1 - 0.0081 16.2 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Apt1 PF10351.9 CDJ56601.1 - 0.017 14.0 16.7 0.02 13.7 4.3 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain RuvB_N PF05496.12 CDJ56601.1 - 0.021 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ56601.1 - 0.036 14.3 0.0 0.036 14.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 CDJ56601.1 - 0.036 14.0 0.4 0.11 12.5 0.3 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 CDJ56601.1 - 0.07 13.2 0.0 1.2 9.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CDJ56601.1 - 0.073 12.0 0.0 0.2 10.6 0.0 1.7 1 1 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ESM4 PF15952.5 CDJ56601.1 - 0.23 11.9 21.9 0.65 10.4 9.2 3.2 3 0 0 3 3 3 0 Enhancer of split M4 family Macoilin PF09726.9 CDJ56601.1 - 0.58 8.6 26.5 0.6 8.6 4.2 2.3 2 0 0 2 2 2 0 Macoilin family AAA_23 PF13476.6 CDJ56601.1 - 0.61 10.5 13.6 2.2 8.7 5.6 3.3 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ56601.1 - 1.4 8.8 50.8 0.11 12.4 27.1 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ56601.1 - 1.9 7.9 13.7 0.93 8.8 4.6 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 CDJ56601.1 - 2.1 8.1 15.1 3.1 7.5 0.9 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 CDJ56601.1 - 5.4 4.8 7.9 1.3 6.8 1.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA_17 PF13207.6 CDJ56601.1 - 7.1 7.1 12.9 7.2 7.0 0.1 3.4 3 0 0 3 3 3 0 AAA domain Dehydrin PF00257.19 CDJ56602.1 - 1.4 9.5 20.8 5.7 7.5 2.9 4.3 4 1 0 4 4 4 0 Dehydrin HAGH_C PF16123.5 CDJ56604.1 - 5.3e-12 46.1 0.0 8.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDJ56604.1 - 1.1e-09 38.7 0.8 1.8e-09 37.9 0.8 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ56604.1 - 0.057 12.9 0.1 0.17 11.3 0.1 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain CRAL_TRIO PF00650.20 CDJ56605.1 - 7.6e-06 25.7 0.1 1.6e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ56605.1 - 0.00013 22.1 0.2 0.00025 21.2 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MoaF PF10703.9 CDJ56605.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 MoaF N-terminal domain Pup PF05639.11 CDJ56605.1 - 4.1 8.4 6.4 11 7.0 6.4 1.8 1 0 0 1 1 1 0 Pup-like protein MORN PF02493.20 CDJ56606.1 - 9.9e-18 62.9 30.2 1.6e-06 27.7 0.5 6.1 6 0 0 6 6 6 4 MORN repeat P53_tetramer PF07710.11 CDJ56607.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif Patched PF02460.18 CDJ56608.1 - 2e-81 274.3 0.5 6.6e-55 186.6 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ56608.1 - 8.7e-30 103.6 7.2 8.7e-30 103.6 7.2 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDJ56608.1 - 0.06 11.0 5.7 0.094 10.4 5.7 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PAS_4 PF08448.10 CDJ56609.1 - 0.086 13.1 1.1 0.41 10.9 1.1 2.2 1 0 0 1 1 1 0 PAS fold Plasmodium_Vir PF05795.11 CDJ56612.1 - 0.0064 16.0 1.5 0.009 15.5 1.5 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein RNA_pol_Rpc4 PF05132.14 CDJ56612.1 - 0.59 10.6 10.4 1.3 9.5 0.9 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 HNF-1_N PF04814.13 CDJ56612.1 - 1 9.9 8.6 1.5 9.4 3.3 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SMYLE_N PF18615.1 CDJ56612.1 - 2.9 7.3 9.7 2 7.9 2.6 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain GREB1 PF15782.5 CDJ56612.1 - 4.5 4.3 6.1 5.4 4.0 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5542 PF17696.1 CDJ56612.1 - 5.3 7.2 6.8 3.1 8.0 2.7 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5542) Pyr_redox_dim PF02852.22 CDJ56614.1 - 1.8e-24 86.1 0.0 1.6e-23 83.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain AC_N PF16214.5 CDJ56614.1 - 0.25 10.5 0.5 0.3 10.2 0.5 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Roc PF08477.13 CDJ56615.1 - 0.00029 21.1 0.8 0.42 10.8 0.0 3.0 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RskA PF10099.9 CDJ56615.1 - 0.0055 17.0 4.7 0.0061 16.9 3.7 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Orf78 PF06024.12 CDJ56615.1 - 0.006 16.9 2.4 0.0088 16.3 2.4 1.2 1 0 0 1 1 1 1 Orf78 (ac78) EIIBC-GUT_N PF03612.14 CDJ56615.1 - 0.012 15.4 3.0 0.018 14.8 3.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ56615.1 - 0.047 12.4 0.4 0.063 12.0 0.4 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 CDJ56615.1 - 0.07 12.4 1.9 0.11 11.7 1.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4834 PF16118.5 CDJ56615.1 - 0.31 12.0 5.4 0.58 11.2 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) 7TM_transglut PF14402.6 CDJ56615.1 - 0.54 9.7 5.1 0.71 9.3 5.1 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Pex14_N PF04695.13 CDJ56615.1 - 0.64 10.7 9.8 1.2 9.7 9.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_Mycoplasma PF07672.13 CDJ56615.1 - 0.76 9.0 3.6 1 8.6 3.6 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Spt20 PF12090.8 CDJ56615.1 - 1 8.9 28.9 1.5 8.4 28.9 1.1 1 0 0 1 1 1 0 Spt20 family TFIIF_alpha PF05793.12 CDJ56616.1 - 0.0016 17.2 31.4 0.0021 16.8 31.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIA PF03153.13 CDJ56616.1 - 0.07 13.1 44.4 0.089 12.8 44.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ56616.1 - 0.54 8.5 32.8 0.66 8.2 32.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Copper-bind PF00127.20 CDJ56616.1 - 0.76 10.3 2.8 4.5 7.8 1.0 2.4 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family DUF853 PF05872.12 CDJ56616.1 - 3.9 6.0 16.5 5.1 5.6 16.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF1682 PF07946.14 CDJ56616.1 - 4.3 6.5 12.5 6.6 5.8 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Sin_N PF04801.13 CDJ56616.1 - 4.8 6.3 25.9 6.5 5.8 25.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DDRGK PF09756.9 CDJ56616.1 - 9.4 5.8 24.2 14 5.2 24.2 1.3 1 0 0 1 1 1 0 DDRGK domain Trp_oprn_chp PF09534.10 CDJ56617.1 - 0.00079 19.3 10.3 0.00079 19.3 10.3 10.0 4 2 6 10 10 10 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BAF1_ABF1 PF04684.13 CDJ56617.1 - 0.0021 17.2 3.9 0.0021 17.2 3.9 7.0 5 1 1 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor Myc_N PF01056.18 CDJ56617.1 - 0.0058 16.6 2.5 0.0058 16.6 2.5 6.7 5 2 1 7 7 7 1 Myc amino-terminal region RskA PF10099.9 CDJ56617.1 - 0.0062 16.8 9.2 0.0062 16.8 9.2 13.0 3 2 5 9 9 9 3 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ56617.1 - 0.01 16.8 6.9 0.01 16.8 6.9 11.6 10 1 0 10 10 10 0 Domain of unknown function (DUF4834) Cyt_bd_oxida_II PF02322.15 CDJ56617.1 - 9.4 5.5 12.2 0.53 9.6 4.2 2.5 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II PT PF04886.12 CDJ56618.1 - 5.8e-12 44.9 67.7 0.00031 20.2 22.6 3.8 1 1 1 2 2 1 1 PT repeat Cullin PF00888.22 CDJ56618.1 - 4.9e-10 38.7 0.0 0.00023 19.9 1.1 2.2 1 1 1 2 2 2 2 Cullin family Baculo_PP31 PF05311.11 CDJ56618.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MID_MedPIWI PF18296.1 CDJ56618.1 - 0.017 14.9 0.4 0.017 14.9 0.4 2.1 2 0 0 2 2 2 0 MID domain of medPIWI Lin-8 PF03353.15 CDJ56618.1 - 0.021 14.4 3.6 0.034 13.7 3.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 CDJ56618.1 - 0.024 15.0 0.8 0.037 14.4 0.8 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Peroxin-13_N PF04088.13 CDJ56618.1 - 0.13 12.5 0.2 0.87 9.9 0.8 2.0 3 0 0 3 3 3 0 Peroxin 13, N-terminal region PXA PF02194.15 CDJ56618.1 - 0.14 12.1 2.0 0.23 11.4 2.0 1.3 1 0 0 1 1 1 0 PXA domain Presenilin PF01080.17 CDJ56618.1 - 0.38 9.5 4.2 0.5 9.1 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ56618.1 - 0.67 7.8 14.5 0.85 7.5 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.16 CDJ56618.1 - 0.76 9.8 3.2 3 7.8 4.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gastrin PF00918.17 CDJ56618.1 - 0.87 10.6 6.3 1.5 9.8 6.3 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family ATP-synt_E PF05680.12 CDJ56618.1 - 1.4 9.3 6.1 3.1 8.2 6.1 1.5 1 0 0 1 1 1 0 ATP synthase E chain DUF4407 PF14362.6 CDJ56618.1 - 1.6 8.0 4.9 2.4 7.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP_sp32 PF07222.12 CDJ56618.1 - 8.3 5.8 10.8 16 4.8 10.8 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Otopetrin PF03189.13 CDJ56619.1 - 1.9 7.2 31.8 7.2 5.3 2.9 6.1 3 1 0 3 3 3 0 Otopetrin DUF4667 PF15700.5 CDJ56620.1 - 0.00096 19.3 7.8 0.00096 19.3 7.8 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4667) Chorion_2 PF03964.15 CDJ56620.1 - 0.0061 17.4 10.0 0.024 15.5 1.8 6.2 3 2 3 6 6 6 2 Chorion family 2 RNA_pol_A_CTD PF03118.15 CDJ56620.1 - 0.022 14.5 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF572 PF04502.13 CDJ56620.1 - 0.28 10.8 38.9 0.61 9.7 9.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2045 PF09741.9 CDJ56620.1 - 3.4 7.0 10.7 9.1 5.6 1.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2045) CD20 PF04103.15 CDJ56621.1 - 8.7 6.4 5.6 1.6 8.8 0.2 2.2 1 1 1 2 2 2 0 CD20-like family SDA1 PF05285.12 CDJ56622.1 - 1.3 8.4 8.5 1.4 8.3 8.5 1.2 1 0 0 1 1 1 0 SDA1 SLC12 PF03522.15 CDJ56622.1 - 2.8 6.9 7.9 3.2 6.7 7.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 POTRA_TamA_1 PF17243.2 CDJ56623.1 - 0.17 12.0 3.6 0.38 10.9 3.6 1.5 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Env-gp36 PF09590.10 CDJ56623.1 - 0.24 9.8 0.1 0.26 9.7 0.1 1.0 1 0 0 1 1 1 0 Lentivirus surface glycoprotein OmpH PF03938.14 CDJ56623.1 - 0.41 11.0 9.8 0.55 10.6 9.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NUDE_C PF04880.13 CDJ56623.1 - 0.94 9.9 6.6 1.5 9.3 6.7 1.3 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region FliD_N PF02465.18 CDJ56623.1 - 0.98 10.2 6.6 3.2 8.5 6.6 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HBS1_N PF08938.10 CDJ56623.1 - 1.5 9.2 4.4 4 7.8 4.3 1.9 1 1 0 1 1 1 0 HBS1 N-terminus ANAPC_CDC26 PF10471.9 CDJ56623.1 - 4.4 8.2 13.4 12 6.8 13.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Rad21_Rec8 PF04824.16 CDJ56624.1 - 0.0011 18.2 0.0 0.0034 16.6 0.0 1.9 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Phage_Mu_Gp45 PF06890.12 CDJ56624.1 - 0.019 14.7 0.5 0.25 11.1 0.3 2.8 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein SPRY PF00622.28 CDJ56625.1 - 0.059 13.5 0.0 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 SPRY domain zf-RING_2 PF13639.6 CDJ56626.1 - 7.6e-09 35.8 11.2 3.7e-08 33.6 3.5 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CDJ56626.1 - 1.1e-07 31.7 7.2 2.4e-07 30.6 1.7 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ56626.1 - 1.1e-07 31.6 7.4 1.9e-07 30.8 3.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ56626.1 - 1.2e-06 28.3 7.6 2.1e-06 27.5 2.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ56626.1 - 2.1e-06 27.9 0.8 2.1e-06 27.9 0.8 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ56626.1 - 2.6e-06 27.4 4.4 2.5e-05 24.2 0.7 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ56626.1 - 5.9e-06 26.1 1.3 5.9e-06 26.1 1.3 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ56626.1 - 8.1e-06 25.6 4.7 0.00012 21.9 1.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ56626.1 - 0.0088 16.2 2.0 0.0088 16.2 2.0 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDJ56626.1 - 0.079 12.8 3.6 0.046 13.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDJ56626.1 - 0.27 11.1 6.4 0.16 11.8 1.5 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CDJ56626.1 - 0.47 10.2 6.2 2.8 7.8 0.7 3.2 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CDJ56626.1 - 1.3 9.2 3.6 0.42 10.7 0.5 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CDJ56626.1 - 1.7 8.8 7.1 0.65 10.2 2.0 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF3984 PF13136.6 CDJ56627.1 - 0.0091 15.4 0.9 0.018 14.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Presenilin PF01080.17 CDJ56627.1 - 0.13 11.0 3.1 0.24 10.2 3.1 1.4 1 0 0 1 1 1 0 Presenilin HEAT PF02985.22 CDJ56627.1 - 0.21 11.9 13.5 0.96 9.9 0.1 5.9 5 0 0 5 5 5 0 HEAT repeat SpoIIP PF07454.11 CDJ56627.1 - 0.7 9.3 3.2 1.2 8.5 3.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ56627.1 - 2.1 8.5 6.1 4 7.6 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2722 PF10846.8 CDJ56627.1 - 2.5 7.0 15.4 0.24 10.3 10.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ56627.1 - 2.8 7.9 7.6 6.5 6.8 7.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ribosomal_S15 PF00312.22 CDJ56628.1 - 1.6e-22 79.5 1.6 2.3e-22 79.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ank_2 PF12796.7 CDJ56629.1 - 1.5e-33 115.2 2.0 8.5e-11 42.3 0.2 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ56629.1 - 4e-26 90.7 4.2 4e-09 36.6 0.2 7.0 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ56629.1 - 1.4e-23 80.4 1.9 0.013 16.0 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDJ56629.1 - 2.8e-23 81.3 7.2 0.0081 16.6 0.1 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CDJ56629.1 - 5.8e-22 77.8 1.4 2.3e-06 28.1 0.3 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) TPR_2 PF07719.17 CDJ56629.1 - 7.2e-06 25.7 4.2 0.0074 16.3 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ56629.1 - 0.037 14.4 0.1 15 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CSN5_C PF18323.1 CDJ56629.1 - 0.049 14.5 0.1 0.17 12.8 0.1 1.9 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain TPR_9 PF13371.6 CDJ56629.1 - 0.1 12.8 6.5 3.1 8.0 1.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ56629.1 - 0.11 12.2 3.8 5.7 6.7 0.2 3.4 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 CDJ56629.1 - 0.11 13.4 17.3 0.68 10.9 1.0 5.0 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56629.1 - 0.11 13.0 6.7 0.6 10.7 6.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56629.1 - 0.26 11.2 5.0 1.3 8.9 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56629.1 - 0.42 11.3 15.0 1.7 9.4 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.26 CDJ56630.1 - 2e-21 76.1 0.0 2.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SMC_N PF02463.19 CDJ56633.1 - 1.7e-36 125.7 29.8 5.4e-35 120.8 29.8 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ56633.1 - 5.6e-17 62.5 0.3 2.5e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 CDJ56633.1 - 4.2e-12 46.4 0.1 5.5e-11 42.8 0.0 3.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 CDJ56633.1 - 4.5e-05 23.1 0.0 9.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CDJ56633.1 - 0.00023 21.0 11.8 0.00023 21.0 11.8 5.9 2 2 1 3 3 3 1 AAA ATPase domain SUIM_assoc PF16619.5 CDJ56633.1 - 0.0036 17.3 0.4 0.0036 17.3 0.4 19.2 13 5 5 18 18 18 3 Unstructured region C-term to UIM in Ataxin3 ABC_tran PF00005.27 CDJ56633.1 - 0.099 13.2 0.2 0.099 13.2 0.2 8.2 3 2 2 5 5 5 0 ABC transporter Csm4_C PF17953.1 CDJ56633.1 - 0.13 12.1 0.2 0.51 10.2 0.2 2.1 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain MGC-24 PF05283.11 CDJ56634.1 - 0.00028 21.4 1.5 0.00037 21.0 1.5 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin dsRBD2 PF17842.1 CDJ56634.1 - 0.071 13.3 0.0 0.089 13.0 0.0 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 CDK2AP PF09806.9 CDJ56634.1 - 0.49 10.4 5.9 0.64 10.0 5.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.9 CDJ56634.1 - 1.3 8.6 9.8 1.6 8.3 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRR18 PF15671.5 CDJ56634.1 - 2.1 8.2 9.0 2.5 7.9 9.0 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 DUF2631 PF10939.8 CDJ56635.1 - 0.085 12.7 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Chorein_N PF12624.7 CDJ56636.1 - 5.9e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ56636.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Myb_DNA-binding PF00249.31 CDJ56637.1 - 3.6e-18 65.5 14.6 1.5e-11 44.3 1.1 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ56637.1 - 4.7e-17 62.0 1.7 3.2e-12 46.5 2.0 3.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CDJ56637.1 - 8.5e-15 55.0 9.3 8.5e-15 55.0 9.3 3.9 3 1 0 3 3 3 1 pre-mRNA splicing factor component HIG_1_N PF04588.13 CDJ56637.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Rap1_C PF11626.8 CDJ56637.1 - 0.41 10.8 8.1 0.41 10.8 0.1 3.7 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TssC PF17541.2 CDJ56637.1 - 2.5 6.8 4.6 0.35 9.6 0.1 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB Kazal_1 PF00050.21 CDJ56638.1 - 0.00052 20.0 0.2 0.00078 19.4 0.2 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CDJ56638.1 - 0.0013 18.8 0.5 0.0019 18.3 0.5 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Got1 PF04178.12 CDJ56639.1 - 1.7e-31 108.9 19.3 2.5e-31 108.4 19.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Lectin_leg-like PF03388.13 CDJ56640.1 - 4.3e-11 42.6 0.1 1.5e-10 40.8 0.1 1.8 1 1 0 1 1 1 1 Legume-like lectin family Asn_synthase PF00733.21 CDJ56641.1 - 0.0035 17.1 0.1 0.0062 16.2 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase AAA_12 PF13087.6 CDJ56645.1 - 2.6e-38 131.6 0.0 3.1e-30 105.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ56645.1 - 3.3e-08 33.5 5.5 2.4e-07 30.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.6 CDJ56645.1 - 5.8e-08 32.8 0.0 0.0002 21.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA PF00004.29 CDJ56645.1 - 0.0016 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CDJ56645.1 - 0.0025 18.2 0.1 3.2 8.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 CDJ56645.1 - 0.019 15.2 0.0 7.1 6.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.6 CDJ56645.1 - 0.086 12.7 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-C3HC PF07967.13 CDJ56645.1 - 0.11 12.5 0.9 0.26 11.3 0.9 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like AAA_16 PF13191.6 CDJ56645.1 - 0.18 12.2 1.0 0.88 9.9 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_2 PF07724.14 CDJ56646.1 - 1.3e-51 175.2 0.0 1.5e-49 168.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ56646.1 - 2.7e-33 114.0 0.4 2.7e-33 114.0 0.4 2.3 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 CDJ56646.1 - 4.6e-25 88.6 0.0 1.7e-12 47.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ56646.1 - 6e-20 71.1 0.2 3.6e-19 68.6 0.2 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ56646.1 - 1.9e-16 60.3 0.1 2.3e-10 40.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CDJ56646.1 - 1.5e-15 57.0 4.0 2.4e-08 34.0 0.2 3.9 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CDJ56646.1 - 3.6e-09 37.2 11.5 5.8e-06 26.8 0.1 4.9 4 3 1 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CDJ56646.1 - 6.6e-09 35.7 0.0 1.8e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CDJ56646.1 - 2.1e-08 34.5 0.4 0.023 15.0 0.0 4.3 3 1 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 CDJ56646.1 - 2.4e-07 30.9 0.1 0.41 10.5 0.0 4.0 3 0 0 3 3 3 3 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CDJ56646.1 - 4.8e-07 29.9 0.0 0.044 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDJ56646.1 - 1.3e-06 28.1 0.0 0.018 14.6 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 CDJ56646.1 - 1.7e-06 27.6 0.8 0.0086 15.5 0.0 4.2 3 2 0 3 3 3 1 Bacterial TniB protein RuvB_N PF05496.12 CDJ56646.1 - 5.4e-06 26.2 1.7 0.0065 16.2 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDJ56646.1 - 1.1e-05 26.0 0.7 0.076 13.6 0.0 3.8 3 1 0 4 4 2 2 AAA domain IstB_IS21 PF01695.17 CDJ56646.1 - 1.9e-05 24.5 0.0 0.062 13.0 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CDJ56646.1 - 0.00011 22.1 0.0 1.8 8.4 0.0 3.9 4 0 0 4 4 4 2 RsgA GTPase ABC_tran PF00005.27 CDJ56646.1 - 0.00026 21.5 0.2 0.22 12.0 0.0 3.1 3 0 0 3 3 2 1 ABC transporter RNA_helicase PF00910.22 CDJ56646.1 - 0.0004 20.8 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 CDJ56646.1 - 0.00061 19.0 0.1 0.51 9.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 CDJ56646.1 - 0.00066 19.5 0.0 0.59 9.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 CDJ56646.1 - 0.00068 19.8 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 CDJ56646.1 - 0.00098 18.5 0.0 0.066 12.5 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin DUF87 PF01935.17 CDJ56646.1 - 0.0031 17.6 1.6 0.22 11.6 0.0 3.5 4 0 0 4 4 3 1 Helicase HerA, central domain DNA_pol3_delta2 PF13177.6 CDJ56646.1 - 0.0032 17.3 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit TsaE PF02367.17 CDJ56646.1 - 0.0035 17.3 0.0 3.8 7.5 0.0 3.1 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ56646.1 - 0.0065 16.4 0.0 0.55 10.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 CDJ56646.1 - 0.0069 16.3 0.0 0.57 10.0 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDJ56646.1 - 0.0077 16.4 0.1 4.3 7.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 CDJ56646.1 - 0.0088 15.8 0.0 5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CDJ56646.1 - 0.013 15.4 0.3 4.8 7.1 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.6 CDJ56646.1 - 0.014 15.0 0.2 0.31 10.6 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_19 PF13245.6 CDJ56646.1 - 0.014 15.8 0.2 5.3 7.4 0.1 3.7 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CDJ56646.1 - 0.022 15.0 2.8 18 5.5 0.0 4.1 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CDJ56646.1 - 0.024 14.4 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sulfatase_C PF14707.6 CDJ56646.1 - 0.076 13.8 0.1 0.21 12.3 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase AAA_17 PF13207.6 CDJ56646.1 - 0.092 13.2 1.4 3.9 7.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain EcoEI_R_C PF08463.10 CDJ56646.1 - 0.23 11.6 7.6 0.28 11.3 1.9 3.4 3 0 0 3 3 3 0 EcoEI R protein C-terminal phage_tail_N PF08400.10 CDJ56646.1 - 0.32 11.0 1.1 1.2 9.1 0.3 2.4 3 0 0 3 3 2 0 Prophage tail fibre N-terminal COPI_C PF06957.11 CDJ56647.1 - 4.7e-73 246.3 0.0 6.4e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CDJ56647.1 - 4.4e-72 243.6 0.0 1.2e-71 242.1 0.0 1.7 1 1 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CDJ56647.1 - 5.7e-37 125.1 16.9 2.3e-07 31.4 0.5 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ56647.1 - 3e-12 46.7 0.1 4.4e-07 30.1 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NRBF2_MIT PF17169.4 CDJ56647.1 - 0.0085 16.3 0.6 0.023 14.9 0.6 1.7 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 TCL1_MTCP1 PF01840.17 CDJ56647.1 - 0.0086 15.7 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 TCL1/MTCP1 family Nup160 PF11715.8 CDJ56647.1 - 0.026 13.2 8.4 2.3 6.8 0.1 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 CDJ56647.1 - 0.42 10.9 5.0 5 7.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56647.1 - 0.83 10.2 5.3 4.3 7.9 1.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56647.1 - 1.9 9.2 5.4 43 4.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 CDJ56648.1 - 2.9e-08 33.0 4.1 3.9e-08 32.6 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Efg1 PF10153.9 CDJ56649.1 - 2.9e-10 40.5 9.3 2.9e-10 40.5 9.3 2.4 3 0 0 3 3 3 1 rRNA-processing protein Efg1 SesA PF17107.5 CDJ56649.1 - 0.5 10.6 5.6 0.39 10.9 2.2 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Maf PF02545.14 CDJ56650.1 - 1.2e-21 77.3 0.0 3.3e-10 40.1 0.0 2.8 2 1 0 2 2 2 2 Maf-like protein Zn-ribbon_8 PF09723.10 CDJ56650.1 - 0.024 14.7 2.9 0.064 13.4 2.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DSPc PF00782.20 CDJ56651.1 - 5.9e-07 29.4 0.0 1.3e-06 28.3 0.0 1.6 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ56651.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_trans_4_4 PF13579.6 CDJ56651.1 - 0.05 14.0 1.6 0.085 13.3 1.6 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF2380 PF09533.10 CDJ56652.1 - 0.013 15.1 0.8 0.014 15.0 0.8 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) NOC3p PF07540.11 CDJ56653.1 - 3.2e-10 40.3 2.2 3.2e-10 40.3 2.2 4.3 5 1 0 5 5 5 1 Nucleolar complex-associated protein DUF4667 PF15700.5 CDJ56653.1 - 0.0044 17.2 1.1 0.0044 17.2 1.1 5.6 4 2 1 5 5 5 1 Domain of unknown function (DUF4667) Plasmodium_Vir PF05795.11 CDJ56653.1 - 8.8 5.6 30.4 1.9 7.8 11.3 3.5 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Arm PF00514.23 CDJ56654.1 - 4.4e-06 26.5 1.3 4.4e-06 26.5 1.3 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TUG-UBL1 PF11470.8 CDJ56654.1 - 0.023 14.9 1.1 0.066 13.4 0.0 2.3 2 0 0 2 2 2 0 TUG ubiquitin-like domain Shadoo PF14999.6 CDJ56654.1 - 0.038 14.1 1.3 0.038 14.1 1.3 4.7 5 0 0 5 5 5 0 Shadow of prion protein, neuroprotective ALMT PF11744.8 CDJ56654.1 - 6.8 5.4 11.0 19 4.0 11.0 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter Nbl1_Borealin_N PF10444.9 CDJ56655.1 - 0.2 11.3 1.0 0.63 9.7 1.0 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal CdvA PF18822.1 CDJ56655.1 - 1.8 8.4 6.2 65 3.4 4.5 3.1 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Dus PF01207.17 CDJ56656.1 - 4.4e-41 141.0 0.0 4.3e-35 121.3 0.0 2.2 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) FeS PF04060.13 CDJ56656.1 - 3.8 7.3 9.3 25 4.6 0.2 3.7 3 0 0 3 3 3 0 Putative Fe-S cluster PIN_6 PF17146.4 CDJ56657.1 - 1.8e-19 70.0 0.0 4.2e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CDJ56657.1 - 7.7e-19 67.6 0.3 1.4e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like OrfB_Zn_ribbon PF07282.11 CDJ56657.1 - 0.015 15.2 2.2 0.096 12.6 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 CDJ56657.1 - 0.016 14.9 0.6 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 CDJ56657.1 - 0.2 11.6 1.6 7.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal DUF913 PF06025.12 CDJ56657.1 - 0.69 8.8 3.2 1.1 8.2 3.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 CDJ56657.1 - 1 7.3 12.8 1.5 6.8 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 CDJ56657.1 - 4.5 6.6 14.3 6.7 6.0 14.3 1.2 1 0 0 1 1 1 0 SDA1 HEAT PF02985.22 CDJ56658.1 - 0.68 10.3 8.7 3.6 8.1 0.3 4.9 4 0 0 4 4 4 0 HEAT repeat LpqV PF17301.2 CDJ56658.1 - 2.3 8.5 10.7 4.4 7.6 3.5 4.0 3 0 0 3 3 3 0 Putative lipoprotein LpqV DUF1126 PF06565.12 CDJ56659.1 - 1.6e-39 133.9 0.0 1.1e-27 95.9 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 CDJ56659.1 - 0.00091 18.6 0.1 0.0025 17.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ56659.1 - 0.0016 18.8 0.1 0.0064 16.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ56659.1 - 0.0023 17.7 0.7 0.012 15.4 0.4 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ56659.1 - 0.035 14.0 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain ketoacyl-synt PF00109.26 CDJ56660.1 - 5.7e-125 416.0 1.0 3e-61 207.2 0.5 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDJ56660.1 - 2.5e-70 233.9 1.2 1.5e-34 118.5 0.1 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 CDJ56660.1 - 3.9e-11 43.1 0.0 1.3e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CDJ56660.1 - 4.3e-06 27.1 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ56660.1 - 0.00018 21.0 7.4 0.0095 15.3 0.4 3.0 3 0 0 3 3 3 2 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CDJ56660.1 - 0.008 16.0 0.4 0.008 16.0 0.4 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2722 PF10846.8 CDJ56663.1 - 4.6e-05 22.6 9.1 4.6e-05 22.6 9.1 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ56663.1 - 0.0028 17.7 20.3 0.0028 17.7 20.3 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ56663.1 - 0.0091 15.6 6.6 0.015 14.8 6.6 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Pal1 PF08316.11 CDJ56663.1 - 0.014 16.2 1.6 0.048 14.4 1.6 1.9 1 0 0 1 1 1 0 Pal1 cell morphology protein Lipase_GDSL PF00657.22 CDJ56663.1 - 0.015 15.3 0.0 0.15 12.0 0.8 2.1 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase Dynein_AAA_lid PF17852.1 CDJ56663.1 - 0.041 14.0 1.2 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain FAM176 PF14851.6 CDJ56663.1 - 0.068 12.8 4.7 1.3 8.7 3.7 2.4 2 0 0 2 2 2 0 FAM176 family DDHD PF02862.17 CDJ56663.1 - 0.085 13.0 3.2 0.16 12.1 3.2 1.5 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 CDJ56663.1 - 0.097 12.3 25.5 0.19 11.3 25.5 1.4 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ56663.1 - 0.15 11.1 8.8 0.33 10.0 8.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein DUF4407 PF14362.6 CDJ56663.1 - 0.45 9.8 10.2 0.23 10.8 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CDJ56663.1 - 0.74 9.8 1.9 1.2 9.1 1.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ56663.1 - 1.1 9.0 5.7 4.3 7.1 6.1 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ56663.1 - 2.2 7.0 7.6 3.9 6.1 7.6 1.3 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 CDJ56663.1 - 2.2 8.7 10.6 5.3 7.5 10.6 1.6 1 0 0 1 1 1 0 AAA domain EIF4E-T PF10477.9 CDJ56663.1 - 2.5 6.8 16.5 4.5 6.0 16.5 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1178 PF06676.11 CDJ56663.1 - 3 8.2 9.8 1.6 9.2 7.2 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1178) Suf PF05843.14 CDJ56663.1 - 3.5 7.5 11.1 5.8 6.8 11.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CDJ56663.1 - 3.9 7.5 14.4 6.4 6.8 14.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Macoilin PF09726.9 CDJ56663.1 - 4 5.9 10.0 6.8 5.1 10.0 1.3 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CDJ56663.1 - 5.5 5.5 13.6 8.7 4.9 13.6 1.2 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CDJ56663.1 - 7.3 5.4 12.2 12 4.8 12.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Use1 PF09753.9 CDJ56664.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 bZIP_1 PF00170.21 CDJ56664.1 - 0.02 15.0 1.9 0.052 13.6 1.9 1.8 1 1 0 1 1 1 0 bZIP transcription factor UPF0242 PF06785.11 CDJ56664.1 - 2.1 8.4 5.7 0.37 10.9 0.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRMT5_TIM PF17285.2 CDJ56666.1 - 1.5e-31 109.5 0.5 8.5e-31 107.1 0.5 2.2 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CDJ56666.1 - 6.3e-29 101.0 6.7 2.6e-24 86.0 0.1 3.7 3 1 0 3 3 3 2 PRMT5 arginine-N-methyltransferase RskA PF10099.9 CDJ56666.1 - 0.0023 18.3 15.1 0.0023 18.3 15.1 9.8 7 2 1 8 8 8 4 Anti-sigma-K factor rskA Helicase_C_2 PF13307.6 CDJ56667.1 - 4.8e-40 137.5 0.0 4.8e-40 137.5 0.0 2.8 3 1 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ56667.1 - 9.7e-30 103.5 5.1 2.4e-16 59.9 0.0 4.6 3 1 0 3 3 3 3 DEAD_2 HBB PF06777.11 CDJ56667.1 - 1.7e-11 44.2 8.1 0.00039 20.1 0.1 3.7 2 1 2 4 4 4 3 Helical and beta-bridge domain Spt20 PF12090.8 CDJ56667.1 - 0.0052 16.4 5.3 0.0052 16.4 5.3 3.4 2 1 0 2 2 2 1 Spt20 family DUF2722 PF10846.8 CDJ56667.1 - 0.018 14.0 43.5 0.011 14.7 5.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) FSA_C PF10479.9 CDJ56667.1 - 0.56 8.3 2.7 0.87 7.6 2.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NEMP PF10225.9 CDJ56667.1 - 0.98 9.0 9.2 2.8 7.6 1.1 2.4 2 0 0 2 2 2 0 NEMP family RAP1 PF07218.11 CDJ56667.1 - 1 7.6 6.8 1.7 6.8 6.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.13 CDJ56667.1 - 4.8 7.8 38.1 0.88 10.2 2.0 4.3 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3817 PF12823.7 CDJ56670.1 - 0.11 13.3 5.4 25 5.8 5.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3817) RskA PF10099.9 CDJ56672.1 - 0.0022 18.3 6.8 0.0022 18.3 6.8 3.2 2 1 1 3 3 3 1 Anti-sigma-K factor rskA SLATT_1 PF18181.1 CDJ56672.1 - 0.054 13.4 0.3 0.054 13.4 0.3 3.2 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 RRF PF01765.19 CDJ56672.1 - 0.13 12.2 7.8 0.41 10.6 7.8 1.8 1 1 0 1 1 1 0 Ribosome recycling factor FHIPEP PF00771.20 CDJ56672.1 - 0.17 10.3 7.2 4.6 5.6 0.0 2.2 2 0 0 2 2 2 0 FHIPEP family DUF2722 PF10846.8 CDJ56672.1 - 0.44 9.4 0.0 0.44 9.4 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2722) BRCA2 PF00634.18 CDJ56673.1 - 5.3e-22 77.2 2.8 4.9e-05 22.9 0.0 5.4 5 0 0 5 5 5 5 BRCA2 repeat Sporozoite_P67 PF05642.11 CDJ56673.1 - 8.6e-06 24.1 0.0 8.6e-06 24.1 0.0 12.5 4 3 2 8 8 8 1 Sporozoite P67 surface antigen BRCA-2_OB1 PF09103.10 CDJ56673.1 - 0.00021 21.2 0.0 0.00021 21.2 0.0 4.9 5 1 0 5 5 5 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 SR-25 PF10500.9 CDJ56673.1 - 0.00095 18.8 23.8 0.00095 18.8 23.8 16.0 10 3 7 18 18 18 4 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ56674.1 - 5.9e-06 25.5 1.6 5.9e-06 25.5 1.6 6.1 5 1 0 5 5 5 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ56674.1 - 0.51 10.6 0.0 0.51 10.6 0.0 8.7 3 3 5 8 8 8 0 Anti-sigma-K factor rskA Dynamin_N PF00350.23 CDJ56674.1 - 3.4 7.7 9.6 1.5 8.9 0.2 3.5 3 0 0 3 3 3 0 Dynamin family Cwf_Cwc_15 PF04889.12 CDJ56675.1 - 0.0016 18.2 12.2 0.0016 18.2 12.2 4.6 3 1 1 4 4 4 2 Cwf15/Cwc15 cell cycle control protein Dehydrin PF00257.19 CDJ56675.1 - 0.019 15.5 0.1 0.019 15.5 0.1 12.8 6 3 3 9 9 9 0 Dehydrin Ldh_1_N PF00056.23 CDJ56676.1 - 0.22 11.6 1.1 1.4 9.0 0.1 2.5 1 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 CDJ56677.1 - 0.00043 19.9 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ56677.1 - 0.00056 20.4 0.1 0.0025 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 AUX_IAA PF02309.16 CDJ56677.1 - 0.0059 16.5 0.4 0.0059 16.5 0.4 3.8 4 0 0 4 4 4 1 AUX/IAA family Neur_chan_memb PF02932.16 CDJ56677.1 - 0.008 16.3 1.0 0.008 16.3 1.0 4.2 5 0 0 5 5 5 2 Neurotransmitter-gated ion-channel transmembrane region Oleosin PF01277.17 CDJ56677.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.8 4 0 0 4 4 4 0 Oleosin DUF4834 PF16118.5 CDJ56677.1 - 0.088 13.8 0.2 0.088 13.8 0.2 7.7 6 3 1 7 7 7 0 Domain of unknown function (DUF4834) TCP PF03634.13 CDJ56677.1 - 0.67 10.5 0.0 0.67 10.5 0.0 6.4 4 3 2 6 6 6 0 TCP family transcription factor Peptidase_C48 PF02902.19 CDJ56678.1 - 1.2e-11 44.9 0.1 1.2e-11 44.9 0.1 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Neur_chan_memb PF02932.16 CDJ56679.1 - 0.23 11.5 2.5 0.27 11.3 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CDJ56679.1 - 0.38 10.7 18.4 0.47 10.4 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ56679.1 - 0.9 10.2 18.9 1.5 9.5 18.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Folliculin PF11704.8 CDJ56679.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hydin_ADK PF17213.3 CDJ56679.1 - 2.3 8.5 10.3 3 8.1 10.3 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ56679.1 - 3.3 7.6 11.2 4.9 7.0 11.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_hydro_1 PF00232.18 CDJ56680.1 - 0.067 11.6 5.0 0.095 11.1 5.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF572 PF04502.13 CDJ56680.1 - 1 8.9 23.4 0.18 11.4 11.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CDJ56680.1 - 1.3 8.5 22.9 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3807 PF12720.7 CDJ56680.1 - 2.5 8.4 25.9 0.3 11.3 19.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Yos1 PF08571.10 CDJ56680.1 - 4.7 7.6 6.8 2.6 8.4 0.3 3.1 1 1 1 2 2 2 0 Yos1-like Med3 PF11593.8 CDJ56681.1 - 0.63 9.2 2.9 0.7 9.0 2.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ56682.1 - 0.0042 17.4 45.6 0.015 15.6 0.1 3.4 1 1 2 3 3 3 2 Anti-sigma-K factor rskA GREB1 PF15782.5 CDJ56682.1 - 0.1 9.7 18.4 0.14 9.3 18.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ56682.1 - 0.44 8.6 14.9 0.55 8.3 14.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCSAP PF15748.5 CDJ56682.1 - 0.58 10.3 22.4 0.025 14.8 16.5 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated GRDA PF04723.14 CDJ56682.1 - 0.73 9.6 3.7 0.9 9.3 0.1 2.3 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A V_ATPase_I PF01496.19 CDJ56682.1 - 0.75 7.6 13.3 1.1 7.1 13.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ56682.1 - 0.82 9.2 58.8 0.87 9.2 24.9 3.2 3 0 0 3 3 3 0 Spt20 family SR-25 PF10500.9 CDJ56682.1 - 0.92 9.1 21.3 0.25 10.9 12.0 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SKA1 PF07160.12 CDJ56682.1 - 1.3 8.8 25.5 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Nha1_C PF08619.10 CDJ56682.1 - 2.4 7.3 19.5 4.5 6.4 19.5 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4366 PF14283.6 CDJ56682.1 - 2.5 8.1 12.5 0.36 10.9 6.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Tau95_N PF17682.1 CDJ56682.1 - 6.6 6.9 11.4 9.9 6.4 0.7 2.3 2 0 0 2 2 2 0 Tau95 Triple barrel domain TPR_14 PF13428.6 CDJ56683.1 - 2.2e-09 37.4 21.0 0.0037 17.9 0.1 5.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ56683.1 - 3.6e-09 36.0 10.3 0.019 15.0 0.5 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56683.1 - 3.3e-08 34.0 31.2 1.4e-05 25.7 16.2 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ56683.1 - 3.4e-08 33.0 4.6 0.00016 21.3 0.0 3.8 2 2 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 CDJ56683.1 - 1.1e-07 31.4 1.5 0.028 14.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56683.1 - 2e-06 27.4 1.7 3.4 7.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ56683.1 - 3.7e-06 27.0 13.7 0.0016 18.6 2.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56683.1 - 0.00015 22.2 12.1 0.012 16.1 6.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ56683.1 - 0.0055 17.0 5.9 1 9.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ56683.1 - 0.006 16.9 16.9 0.11 12.8 4.6 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat FAT PF02259.23 CDJ56683.1 - 0.03 13.6 0.8 0.84 8.8 0.4 2.1 2 0 0 2 2 2 0 FAT domain Lactamase_B_6 PF16661.5 CDJ56684.1 - 0.0034 16.8 0.2 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain PI3_PI4_kinase PF00454.27 CDJ56685.1 - 5.9e-25 88.5 0.0 2.8e-22 79.8 0.0 2.9 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase GOLD_2 PF13897.6 CDJ56685.1 - 3.2 8.2 5.1 1.9e+02 2.5 2.4 4.1 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking ELO PF01151.18 CDJ56687.1 - 5.3e-47 160.5 18.3 6.4e-47 160.2 16.1 2.1 2 1 0 2 2 2 1 GNS1/SUR4 family Cas9-BH PF16593.5 CDJ56688.1 - 0.19 11.4 0.3 0.46 10.3 0.3 1.6 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Pinin_SDK_memA PF04696.13 CDJ56690.1 - 8.7e-18 64.6 11.3 8.7e-18 64.6 11.3 2.0 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Med3 PF11593.8 CDJ56690.1 - 0.059 12.6 8.4 0.091 11.9 8.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Saw1 PF11561.8 CDJ56690.1 - 0.084 12.4 8.1 0.12 11.9 8.1 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Spt20 PF12090.8 CDJ56690.1 - 8 6.0 22.6 0.96 9.0 18.3 1.6 2 0 0 2 2 2 0 Spt20 family Ribosomal_60s PF00428.19 CDJ56692.1 - 0.46 11.1 15.9 0.45 11.1 5.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein O-antigen_lig PF13425.6 CDJ56692.1 - 0.97 8.1 13.0 1.7 7.3 13.0 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 CDJ56692.1 - 5.3 5.3 11.6 8.7 4.6 11.6 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UCH PF00443.29 CDJ56693.1 - 9e-34 117.1 0.3 2.4e-32 112.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ56693.1 - 3.9e-11 43.1 14.5 1.4e-10 41.3 0.0 4.4 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 CDJ56693.1 - 3.2 7.9 5.4 1.8 8.7 0.2 2.9 3 0 0 3 3 3 0 Double zinc ribbon MFS_1 PF07690.16 CDJ56694.1 - 4.1e-15 55.6 40.5 4.2e-10 39.1 0.6 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 CDJ56694.1 - 7.6e-10 37.7 14.3 1.5e-08 33.5 1.4 3.0 2 2 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CDJ56694.1 - 1.8e-07 30.4 9.3 4.6e-07 29.0 0.0 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Vut_1 PF02592.15 CDJ56694.1 - 0.0015 18.9 0.6 0.0015 18.9 0.6 2.9 3 0 0 3 3 3 1 Putative vitamin uptake transporter DUF3043 PF11241.8 CDJ56694.1 - 0.18 11.8 3.9 3.5 7.6 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Spt20 PF12090.8 CDJ56694.1 - 0.78 9.3 28.7 0.028 14.0 18.2 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 CDJ56694.1 - 1 9.3 25.1 2.9 7.8 17.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 CDJ56694.1 - 4.7 5.6 8.6 7.3 4.9 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 S4 PF01479.25 CDJ56695.1 - 2.2e-12 46.5 0.4 2.2e-12 46.5 0.4 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CDJ56695.1 - 3.2e-06 28.0 1.2 5e-06 27.3 0.8 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DOT1 PF08123.13 CDJ56696.1 - 8.3e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 EGF_2 PF07974.13 CDJ56697.1 - 8.6e-24 83.6 182.1 3.5e-05 24.1 11.9 11.1 9 2 2 11 11 11 9 EGF-like domain AMA-1 PF02430.15 CDJ56697.1 - 1.3e-18 67.2 3.0 2.3e-15 56.6 1.0 2.8 3 0 0 3 3 3 2 Apical membrane antigen 1 hEGF PF12661.7 CDJ56697.1 - 9.3e-15 54.6 109.2 0.0088 16.6 3.7 11.4 9 0 0 9 9 9 9 Human growth factor-like EGF EGF PF00008.27 CDJ56697.1 - 0.00021 21.5 139.2 0.0035 17.6 8.6 10.6 8 1 1 9 9 9 6 EGF-like domain CLAG PF03805.13 CDJ56698.1 - 2.5e-06 25.4 0.0 5.2e-06 24.4 0.0 1.4 2 0 0 2 2 2 1 Cytoadherence-linked asexual protein GvpL_GvpF PF06386.11 CDJ56698.1 - 0.13 12.1 3.6 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Rrp15p PF07890.12 CDJ56700.1 - 0.0035 17.7 3.6 0.0043 17.4 3.6 1.1 1 0 0 1 1 1 1 Rrp15p FAM177 PF14774.6 CDJ56700.1 - 0.0044 17.4 1.1 0.0057 17.0 1.1 1.2 1 0 0 1 1 1 1 FAM177 family TFIIA PF03153.13 CDJ56700.1 - 0.035 14.1 9.1 0.032 14.2 9.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ56700.1 - 0.21 11.1 16.9 0.25 10.9 16.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ56700.1 - 3 6.7 14.8 3.2 6.6 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TLD PF07534.16 CDJ56701.1 - 3.2e-10 40.3 0.1 7.1e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 TLD Chorion_2 PF03964.15 CDJ56701.1 - 0.0003 21.6 6.1 0.0003 21.6 6.1 8.2 5 2 1 7 7 7 1 Chorion family 2 DUF1635 PF07795.11 CDJ56701.1 - 0.0036 17.2 9.9 0.0036 17.2 9.9 4.0 5 2 0 5 5 5 1 Protein of unknown function (DUF1635) CDK2AP PF09806.9 CDJ56701.1 - 0.0038 17.3 7.1 0.0038 17.3 7.1 5.6 5 1 0 5 5 5 2 Cyclin-dependent kinase 2-associated protein NDUFB11 PF17250.2 CDJ56701.1 - 0.15 12.7 0.2 0.4 11.3 0.2 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit MitMem_reg PF13012.6 CDJ56702.1 - 2.8e-33 114.7 0.8 4.5e-33 114.0 0.8 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDJ56702.1 - 9.9e-07 28.7 4.1 1.1e-05 25.4 0.2 3.1 2 2 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Actin PF00022.19 CDJ56703.1 - 4.9e-14 51.8 0.0 1.2e-11 43.9 0.0 2.4 2 1 0 2 2 2 2 Actin TRAP_alpha PF03896.16 CDJ56703.1 - 0.2 10.8 1.1 0.27 10.4 1.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Roughex PF06020.11 CDJ56703.1 - 0.23 10.5 6.7 0.36 9.9 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DREPP PF05558.12 CDJ56703.1 - 0.23 11.3 5.1 0.39 10.6 5.1 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide RskA PF10099.9 CDJ56703.1 - 8 6.7 23.2 6.4 7.0 12.5 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_M1_N PF17900.1 CDJ56704.1 - 3e-05 24.3 0.0 0.00023 21.4 0.0 2.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF1892 PF08987.10 CDJ56704.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1892) RskA PF10099.9 CDJ56705.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 12.3 4 3 4 10 10 10 4 Anti-sigma-K factor rskA His_Phos_2 PF00328.22 CDJ56706.1 - 2.2e-23 83.2 12.4 5.8e-15 55.5 0.0 3.3 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 CDJ56706.1 - 8.7e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF2722 PF10846.8 CDJ56706.1 - 0.0044 16.0 6.3 0.0044 16.0 6.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4820 PF16091.5 CDJ56706.1 - 4.8 6.5 13.2 6.5 6.0 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Eapp_C PF10238.9 CDJ56706.1 - 4.8 7.2 11.8 1.1 9.3 0.3 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4834 PF16118.5 CDJ56706.1 - 5.2 8.1 22.2 4.8 8.2 6.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Paf1 PF03985.13 CDJ56706.1 - 6.5 5.6 14.7 3 6.8 4.0 2.2 2 0 0 2 2 2 0 Paf1 Sin_N PF04801.13 CDJ56708.1 - 0.0008 18.7 12.6 0.0008 18.7 12.6 12.1 8 3 1 10 10 10 3 Sin-like protein conserved region DUF1645 PF07816.11 CDJ56708.1 - 0.011 16.3 1.3 0.011 16.3 1.3 18.3 6 5 5 13 13 13 0 Protein of unknown function (DUF1645) CDC27 PF09507.10 CDJ56709.1 - 0.0031 17.0 47.5 0.0031 17.0 47.5 2.5 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 CDJ56709.1 - 5.2 6.6 63.7 0.016 14.8 38.4 2.3 2 0 0 2 2 2 0 PPP4R2 SPX PF03105.19 CDJ56710.1 - 0.0013 18.7 21.4 0.19 11.6 7.8 3.0 3 0 0 3 3 3 2 SPX domain VIR_N PF15912.5 CDJ56710.1 - 0.0023 17.6 5.9 0.0023 17.6 5.9 2.3 2 0 0 2 2 2 1 Virilizer, N-terminal SURF6 PF04935.12 CDJ56710.1 - 0.0073 16.1 22.7 0.026 14.3 10.6 2.5 2 0 0 2 2 2 2 Surfeit locus protein 6 SLC12 PF03522.15 CDJ56710.1 - 0.0075 15.3 19.3 0.013 14.5 19.3 1.4 1 0 0 1 1 1 1 Solute carrier family 12 DUF1645 PF07816.11 CDJ56710.1 - 0.25 11.9 23.4 0.065 13.8 2.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Connexin PF00029.19 CDJ56710.1 - 0.45 10.2 14.7 0.18 11.5 6.2 2.3 2 0 0 2 2 2 0 Connexin RPN2_C PF18004.1 CDJ56710.1 - 0.54 10.2 18.8 0.8 9.6 9.2 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 CDJ56710.1 - 1.2 7.8 19.2 1.4 7.6 8.3 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ferlin_C PF16165.5 CDJ56710.1 - 1.2 9.0 4.6 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferlin C-terminus DUF4746 PF15928.5 CDJ56710.1 - 1.8 7.9 13.9 0.77 9.1 7.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Trypan_glycop_C PF10659.9 CDJ56710.1 - 2.9 8.3 15.2 4.1 7.8 5.2 2.8 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain TFB6 PF17110.5 CDJ56710.1 - 3 7.6 12.9 3.7 7.3 6.3 2.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Slu7 PF11708.8 CDJ56710.1 - 3.2 7.4 24.8 4.1 7.1 12.8 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor NARP1 PF12569.8 CDJ56710.1 - 3.8 6.3 23.0 0.34 9.8 7.6 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3446 PF11928.8 CDJ56710.1 - 4.8 7.5 31.5 0.34 11.2 2.7 4.1 3 0 0 3 3 3 0 Early growth response N-terminal domain Pet20 PF08692.10 CDJ56710.1 - 4.9 7.9 12.9 3.3 8.4 0.2 3.0 3 0 0 3 3 2 0 Mitochondrial protein Pet20 Utp14 PF04615.13 CDJ56710.1 - 6.3 5.2 26.8 0.051 12.2 18.2 1.7 2 0 0 2 2 2 0 Utp14 protein DUF2370 PF10176.9 CDJ56710.1 - 6.7 6.3 9.8 0.75 9.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Serinc PF03348.15 CDJ56710.1 - 6.9 5.5 19.3 0.18 10.7 9.6 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) CPSF100_C PF13299.6 CDJ56710.1 - 7.3 6.7 21.9 1.1 9.4 8.7 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PIP5K PF01504.18 CDJ56710.1 - 7.4 5.7 19.3 5.1 6.2 9.4 2.4 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase ORC_WH_C PF18137.1 CDJ56710.1 - 9.8 6.2 20.5 2.9 8.0 7.0 3.0 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Symplekin_C PF12295.8 CDJ56711.1 - 0.11 12.6 3.6 0.25 11.4 3.6 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal UPF0054 PF02130.17 CDJ56712.1 - 1.9e-13 50.3 4.2 2e-13 50.3 0.3 2.4 2 1 0 2 2 2 1 Uncharacterized protein family UPF0054 DUF2057 PF09829.9 CDJ56712.1 - 0.21 11.8 17.1 1.7 8.7 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Med3 PF11593.8 CDJ56712.1 - 0.73 9.0 34.9 1.3 8.1 20.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal NOA36 PF06524.12 CDJ56714.1 - 0.012 14.9 6.3 0.013 14.9 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 CDJ56714.1 - 0.013 15.2 9.1 0.014 15.2 9.1 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 CDJ56714.1 - 0.014 15.9 24.0 0.014 15.9 24.0 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Myc_N PF01056.18 CDJ56714.1 - 0.061 13.2 2.1 0.058 13.3 2.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 CDJ56714.1 - 0.072 12.3 1.0 0.066 12.4 1.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.12 CDJ56714.1 - 0.084 11.8 6.0 0.082 11.8 6.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 CDJ56714.1 - 0.09 13.2 6.6 0.11 12.9 6.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CDJ56714.1 - 0.11 12.2 3.9 0.12 12.0 3.9 1.1 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 CDJ56714.1 - 0.13 12.2 6.6 0.12 12.2 6.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 CDJ56714.1 - 0.14 10.2 3.4 0.15 10.1 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 CDJ56714.1 - 0.52 8.5 7.5 0.51 8.5 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 CDJ56714.1 - 0.6 9.5 5.2 0.61 9.5 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 CDJ56714.1 - 0.63 8.1 8.7 0.61 8.1 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CDJ56714.1 - 1.2 7.3 7.0 1.3 7.3 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein GOLD_2 PF13897.6 CDJ56714.1 - 1.3 9.5 4.2 1.5 9.3 4.2 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paf1 PF03985.13 CDJ56714.1 - 4.6 6.1 11.3 4.7 6.1 11.3 1.0 1 0 0 1 1 1 0 Paf1 Voldacs PF03517.13 CDJ56714.1 - 4.8 7.3 9.5 6 7.0 9.5 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Kelch_1 PF01344.25 CDJ56715.1 - 6.6e-07 28.8 0.0 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 CDJ56715.1 - 8.6e-06 25.7 0.1 2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ56715.1 - 8.9e-06 25.8 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDJ56715.1 - 1.6e-05 24.6 0.5 3.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CDJ56715.1 - 0.00065 19.6 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 Kelch motif Hamartin PF04388.12 CDJ56715.1 - 0.0025 16.6 33.8 0.003 16.3 33.8 1.0 1 0 0 1 1 1 1 Hamartin protein Kelch_3 PF13415.6 CDJ56715.1 - 0.0032 17.7 0.2 0.012 15.9 0.2 2.0 1 0 0 1 1 1 1 Galactose oxidase, central domain Activator_LAG-3 PF11498.8 CDJ56715.1 - 1.1 8.1 69.0 0.031 13.3 18.2 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peptidase_S64 PF08192.11 CDJ56715.1 - 1.4 7.4 31.7 1.9 6.9 31.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 RR_TM4-6 PF06459.12 CDJ56715.1 - 2 8.1 28.6 1.8 8.3 11.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ56715.1 - 2.1 7.4 59.1 0.22 10.6 26.4 2.1 2 0 0 2 2 2 0 SprA-related family CSRNP_N PF16019.5 CDJ56715.1 - 2.4 8.0 28.1 0.63 9.9 9.1 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4638 PF15472.6 CDJ56715.1 - 3.8 7.2 18.9 1 9.0 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) CTP_transf_1 PF01148.20 CDJ56716.1 - 2.2e-33 116.2 6.3 2.6e-33 115.9 6.3 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Tom22 PF04281.13 CDJ56717.1 - 0.0035 17.1 1.1 0.0035 17.1 1.1 4.6 5 0 0 5 5 5 1 Mitochondrial import receptor subunit Tom22 RskA PF10099.9 CDJ56717.1 - 6.2 7.1 56.1 2.8e+03 -1.6 28.8 5.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA zf-RING_UBOX PF13445.6 CDJ56718.1 - 1.4e-06 28.2 4.5 1.4e-06 28.2 4.5 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ56718.1 - 4.8e-05 23.2 7.9 4.8e-05 23.2 7.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain RskA PF10099.9 CDJ56718.1 - 0.0055 17.0 26.0 1.2 9.4 7.6 2.9 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ56718.1 - 0.0065 16.5 0.4 0.0065 16.5 0.4 3.0 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 zf-C3HC4 PF00097.25 CDJ56718.1 - 0.0079 16.0 8.9 0.0079 16.0 8.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ56718.1 - 0.027 14.8 11.4 0.027 14.8 11.4 2.3 2 0 0 2 2 2 0 Ring finger domain FliD_N PF02465.18 CDJ56718.1 - 0.03 15.0 6.2 0.03 15.0 6.2 2.6 2 0 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus TMEM174 PF15029.6 CDJ56718.1 - 0.067 12.9 1.9 0.084 12.6 0.6 1.7 2 0 0 2 2 2 0 Transmembrane protein 174 Connexin PF00029.19 CDJ56718.1 - 0.13 12.0 2.2 0.28 10.9 1.1 2.0 2 0 0 2 2 2 0 Connexin Tau95_N PF17682.1 CDJ56718.1 - 0.15 12.2 2.3 6.5 7.0 1.8 2.2 2 0 0 2 2 2 0 Tau95 Triple barrel domain DcuA_DcuB PF03605.14 CDJ56718.1 - 0.2 10.5 7.3 0.039 12.8 1.4 2.3 1 1 2 3 3 3 0 Anaerobic c4-dicarboxylate membrane transporter Peroxin-13_N PF04088.13 CDJ56718.1 - 0.22 11.8 4.0 0.17 12.1 0.9 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF5327 PF17261.2 CDJ56718.1 - 0.24 12.2 15.2 1.3 9.8 10.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) zf-C3HC4_4 PF15227.6 CDJ56718.1 - 0.31 11.2 19.0 0.052 13.7 11.2 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CDJ56718.1 - 0.33 10.3 16.8 0.24 10.7 8.8 2.5 1 1 1 2 2 2 0 Rtf2 RING-finger Baculo_PP31 PF05311.11 CDJ56718.1 - 0.85 9.1 5.5 1.8 8.0 3.3 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 CDJ56718.1 - 1.1 8.9 28.8 0.22 11.1 2.7 2.2 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 CDJ56718.1 - 2.3 7.6 7.9 0.49 9.8 3.3 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4746 PF15928.5 CDJ56718.1 - 4.9 6.5 9.8 29 3.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) YABBY PF04690.13 CDJ56718.1 - 5.6 7.5 14.6 1 9.9 5.5 2.8 1 1 1 3 3 3 0 YABBY protein TERB2 PF15101.6 CDJ56718.1 - 6.8 6.7 14.6 1.1 9.2 5.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ56718.1 - 9.2 6.1 33.3 29 4.5 33.8 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1772 PF08592.11 CDJ56718.1 - 9.8 6.5 15.0 2 8.7 11.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) BRCT PF00533.26 CDJ56720.1 - 2.1e-11 44.1 0.0 5.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 CDJ56720.1 - 1.1e-05 25.9 0.0 3.8e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CDJ56720.1 - 0.00078 19.3 0.0 0.00078 19.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CDJ56720.1 - 0.0008 19.7 0.0 0.0047 17.2 0.0 2.4 1 0 0 1 1 1 1 AAA C-terminal domain Methyltransf_23 PF13489.6 CDJ56721.1 - 1.6e-13 50.8 0.1 4.9e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ56721.1 - 7.5e-09 36.2 0.0 1.7e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RFC1 PF08519.12 CDJ56721.1 - 3e-08 34.0 0.0 5.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Methyltransf_11 PF08241.12 CDJ56721.1 - 5.2e-08 33.4 0.1 1.6e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ56721.1 - 3e-07 31.1 0.1 1.1e-06 29.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ56721.1 - 1.4e-06 27.8 0.1 2.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CDJ56721.1 - 0.0019 18.0 0.4 0.0054 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Spt20 PF12090.8 CDJ56721.1 - 0.21 11.2 5.3 0.31 10.6 5.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF1635 PF07795.11 CDJ56721.1 - 0.39 10.5 5.0 0.6 9.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4064 PF13273.6 CDJ56722.1 - 0.09 13.1 1.0 0.39 11.0 1.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SUIM_assoc PF16619.5 CDJ56723.1 - 0.00059 19.8 0.0 0.00059 19.8 0.0 25.2 4 4 13 17 17 17 1 Unstructured region C-term to UIM in Ataxin3 PIG-U PF06728.13 CDJ56723.1 - 0.39 9.7 0.4 2.2 7.2 0.0 2.6 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U Kinesin PF00225.23 CDJ56724.1 - 3.6e-102 341.7 0.0 9e-102 340.4 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ56724.1 - 4.2e-24 85.2 0.0 1.4e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding DKCLD PF08068.12 CDJ56725.1 - 2.1e-28 98.1 0.1 5.2e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CDJ56725.1 - 3.3e-21 75.2 0.8 5.7e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CDJ56725.1 - 5.3e-21 74.4 1.2 9.5e-21 73.5 1.2 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CDJ56725.1 - 6.4e-21 75.3 1.2 7.1e-18 65.4 1.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CDJ56725.1 - 0.003 17.8 0.0 0.0094 16.2 0.0 1.9 1 0 0 1 1 1 1 UPF0113 PUA domain Coilin_N PF15862.5 CDJ56725.1 - 0.015 15.1 3.2 0.03 14.1 3.2 1.5 1 0 0 1 1 1 0 Coilin N-terminus PseudoU_synth_2 PF00849.22 CDJ56725.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA pseudouridylate synthase Evr1_Alr PF04777.13 CDJ56726.1 - 1.5e-08 35.0 4.8 4.3e-06 27.1 1.3 4.1 3 1 0 3 3 3 1 Erv1 / Alr family Thioredoxin PF00085.20 CDJ56726.1 - 2.9e-07 30.4 0.1 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CDJ56726.1 - 0.0029 17.8 0.0 0.0085 16.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDJ56726.1 - 0.065 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 CDJ56726.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain PH_6 PF15406.6 CDJ56726.1 - 0.13 12.6 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain DUF35_N PF12172.8 CDJ56726.1 - 0.4 10.6 10.6 0.4 10.6 1.9 3.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) EGF_3 PF12947.7 CDJ56729.1 - 7.5e-06 26.0 6.8 7.5e-06 26.0 6.8 6.8 5 2 2 7 7 7 3 EGF domain cEGF PF12662.7 CDJ56729.1 - 0.003 17.4 0.7 0.003 17.4 0.7 7.1 8 0 0 8 8 8 3 Complement Clr-like EGF-like Podoplanin PF05808.11 CDJ56729.1 - 0.0078 16.3 0.1 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Podoplanin FXa_inhibition PF14670.6 CDJ56729.1 - 0.0094 16.2 72.2 0.016 15.4 4.2 6.8 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ56729.1 - 0.063 13.5 65.6 0.12 12.6 5.9 6.6 6 0 0 6 6 6 0 Calcium-binding EGF domain SIT PF15330.6 CDJ56729.1 - 0.17 12.4 0.8 0.33 11.4 0.1 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT EGF PF00008.27 CDJ56729.1 - 1.5 9.2 68.5 4.4 7.7 5.8 7.7 5 4 1 6 6 6 0 EGF-like domain zf-CCCH_4 PF18044.1 CDJ56730.1 - 0.14 11.9 0.9 0.28 11.0 0.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ56730.1 - 0.15 12.0 0.9 0.34 10.9 0.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RskA PF10099.9 CDJ56733.1 - 0.0034 17.7 3.8 0.0034 17.7 3.8 11.9 5 2 3 8 8 8 6 Anti-sigma-K factor rskA DUF2418 PF10332.9 CDJ56733.1 - 0.17 12.4 0.4 0.44 11.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Macro PF01661.21 CDJ56734.1 - 7.8e-06 25.9 0.0 0.0044 17.1 0.0 3.3 1 1 1 2 2 2 1 Macro domain DUF2235 PF09994.9 CDJ56734.1 - 0.03 13.7 2.3 0.62 9.4 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) RPA43_OB PF17875.1 CDJ56734.1 - 0.095 13.3 0.1 0.095 13.3 0.1 4.2 5 1 0 5 5 5 0 RPA43 OB domain in RNA Pol I TERB2 PF15101.6 CDJ56735.1 - 0.0014 18.7 11.3 0.0014 18.7 11.3 8.0 5 2 3 8 8 8 2 Telomere-associated protein TERB2 RskA PF10099.9 CDJ56735.1 - 0.19 12.0 0.0 0.019 15.3 7.6 8.7 3 2 4 7 7 7 0 Anti-sigma-K factor rskA GSCFA PF08885.11 CDJ56736.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 GSCFA family DUF3523 PF12037.8 CDJ56737.1 - 3.3e-80 269.3 35.2 3.3e-80 269.3 35.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 CDJ56737.1 - 6.1e-13 49.3 0.1 2.8e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ56737.1 - 0.00064 19.5 0.0 0.0024 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain SDH_beta PF03315.15 CDJ56737.1 - 0.24 11.8 7.2 0.057 13.8 2.4 2.5 2 1 0 2 2 2 0 Serine dehydratase beta chain DUF4168 PF13767.6 CDJ56738.1 - 0.0042 18.2 0.1 0.011 16.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4168) Uteroglobin PF01099.17 CDJ56738.1 - 0.053 13.9 0.0 16 5.9 0.0 2.3 2 0 0 2 2 2 0 Uteroglobin family HECT PF00632.25 CDJ56739.1 - 5.1e-31 108.3 0.0 2.8e-30 105.8 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Apt1 PF10351.9 CDJ56740.1 - 0.0014 17.6 3.4 0.0019 17.2 3.4 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF4667 PF15700.5 CDJ56740.1 - 0.015 15.4 2.7 0.015 15.4 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Secretin_N_2 PF07655.13 CDJ56740.1 - 0.42 11.2 35.1 0.56 10.8 12.8 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain EBP50_C PF09007.11 CDJ56740.1 - 3.8 8.5 11.3 13 6.8 0.7 2.2 2 0 0 2 2 2 0 EBP50, C-terminal TAF4 PF05236.14 CDJ56740.1 - 4.4 7.0 6.9 3.3 7.4 1.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MACPF PF01823.19 CDJ56740.1 - 6.2 6.8 9.1 9.6 6.2 1.9 2.1 2 0 0 2 2 2 0 MAC/Perforin domain Pex14_N PF04695.13 CDJ56743.1 - 1.4 9.6 34.0 0.17 12.5 16.0 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region N6_N4_Mtase PF01555.18 CDJ56744.1 - 0.063 13.0 0.0 0.63 9.7 0.0 2.6 1 1 0 1 1 1 0 DNA methylase SR-25 PF10500.9 CDJ56745.1 - 0.0083 15.8 9.0 0.011 15.4 9.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM104 PF15434.6 CDJ56745.1 - 0.06 13.9 6.0 0.073 13.6 6.0 1.1 1 0 0 1 1 1 0 Family 104 DUF4813 PF16072.5 CDJ56745.1 - 0.1 12.3 12.4 0.12 12.0 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RskA PF10099.9 CDJ56745.1 - 0.13 12.6 11.9 0.16 12.3 11.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CCDC106 PF15794.5 CDJ56745.1 - 0.44 10.2 7.7 0.54 9.9 7.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Gti1_Pac2 PF09729.9 CDJ56745.1 - 1.3 9.1 5.3 1.5 8.8 5.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Macoilin PF09726.9 CDJ56745.1 - 3.2 6.2 8.5 4.4 5.7 8.5 1.2 1 0 0 1 1 1 0 Macoilin family CAML PF14963.6 CDJ56745.1 - 3.4 7.7 5.4 3.9 7.5 5.4 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PI3K_1B_p101 PF10486.9 CDJ56745.1 - 4.2 5.0 5.8 4.9 4.8 5.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 CDJ56745.1 - 6.1 5.5 9.3 7 5.3 9.3 1.0 1 0 0 1 1 1 0 Presenilin MRI PF15325.6 CDJ56745.1 - 6.7 7.9 12.6 8.1 7.6 12.2 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection CDK2AP PF09806.9 CDJ56745.1 - 8.6 6.3 24.8 15 5.6 24.8 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2207 PF09972.9 CDJ56746.1 - 0.044 12.6 0.2 0.044 12.6 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UPRTase PF14681.6 CDJ56746.1 - 3.8 6.9 7.8 0.16 11.4 0.4 2.1 2 1 0 2 2 2 0 Uracil phosphoribosyltransferase DUF5345 PF17280.2 CDJ56746.1 - 4.2 7.4 29.4 0.035 14.1 4.8 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Pkinase PF00069.25 CDJ56748.1 - 3.2e-07 30.0 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56748.1 - 0.00016 21.1 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ56749.1 - 4.4e-13 49.2 0.0 8.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ56749.1 - 5e-09 35.9 0.0 8.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ56749.1 - 7.2e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ56749.1 - 0.022 14.1 0.0 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 CDJ56750.1 - 1.4 7.5 6.0 2.1 6.9 6.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF908 PF06012.12 CDJ56750.1 - 5.7 6.2 13.0 12 5.1 13.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4551 PF15087.6 CDJ56750.1 - 6.2 5.5 11.9 9.2 5.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lin-8 PF03353.15 CDJ56750.1 - 8.7 5.8 7.5 21 4.6 7.5 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CRT-like PF08627.10 CDJ56751.1 - 4.1e-76 256.1 10.0 8.3e-43 146.6 0.7 2.0 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 CDJ56751.1 - 0.0014 18.2 0.3 0.0014 18.2 0.3 1.6 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 CDJ56751.1 - 0.0023 18.1 2.8 0.0023 18.1 2.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 CDJ56751.1 - 0.29 10.3 6.1 0.036 13.3 0.5 2.0 2 0 0 2 2 2 0 UAA transporter family Pkinase_Tyr PF07714.17 CDJ56752.1 - 7.6e-15 54.9 2.3 9.5e-08 31.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CDJ56752.1 - 2.2e-08 33.8 9.0 5.3e-05 22.7 0.0 4.0 3 1 1 4 4 4 2 Protein kinase domain AAA_11 PF13086.6 CDJ56752.1 - 0.0054 16.6 6.3 0.012 15.5 6.3 1.5 1 0 0 1 1 1 1 AAA domain MecA PF05389.12 CDJ56752.1 - 0.0071 16.0 1.1 0.0071 16.0 1.1 2.2 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) CAF1 PF04857.20 CDJ56752.1 - 0.0091 15.2 1.9 0.016 14.4 1.9 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease EOS1 PF12326.8 CDJ56752.1 - 0.031 14.2 3.3 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein MORN PF02493.20 CDJ56752.1 - 0.069 13.1 0.2 0.19 11.7 0.0 1.9 2 0 0 2 2 1 0 MORN repeat EPL1 PF10513.9 CDJ56752.1 - 0.11 12.9 20.1 0.26 11.7 0.2 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like XRN_M PF17846.1 CDJ56752.1 - 0.27 10.1 5.6 0.44 9.4 5.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain TFIIA PF03153.13 CDJ56752.1 - 0.36 10.8 64.4 0.27 11.2 31.5 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ56752.1 - 0.47 10.6 18.3 1 9.5 5.7 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Eapp_C PF10238.9 CDJ56752.1 - 0.49 10.5 17.9 1.2 9.1 7.8 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3801 PF12687.7 CDJ56752.1 - 0.66 10.0 18.2 2.1 8.4 10.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) Velvet PF11754.8 CDJ56752.1 - 0.88 9.5 19.6 1.4 8.8 7.8 3.2 3 0 0 3 3 3 0 Velvet factor eIF3_subunit PF08597.10 CDJ56752.1 - 1.2 9.0 17.3 0.64 9.9 4.2 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pex14_N PF04695.13 CDJ56752.1 - 1.7 9.3 44.8 0.15 12.7 18.2 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ56752.1 - 2.5 7.8 14.3 0.28 10.9 2.0 2.2 2 0 0 2 2 2 0 Connexin Ribosomal_60s PF00428.19 CDJ56752.1 - 2.7 8.6 30.8 14 6.4 8.5 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein SMYLE_N PF18615.1 CDJ56752.1 - 2.7 7.4 13.5 0.15 11.6 3.4 2.3 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CSG2 PF16965.5 CDJ56752.1 - 3.4 6.5 6.6 0.88 8.5 0.2 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator eIF-3_zeta PF05091.12 CDJ56752.1 - 6 5.7 29.8 0.092 11.7 10.6 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 CDJ56752.1 - 6.5 6.4 14.5 4.3 7.0 4.3 2.5 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.8 CDJ56752.1 - 7.8 5.2 19.6 4.6 5.9 9.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CDJ56752.1 - 8.5 5.5 7.1 26 3.9 0.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter FAM91_C PF14648.6 CDJ56752.1 - 8.9 5.0 8.5 28 3.4 5.2 2.1 2 0 0 2 2 2 0 FAM91 C-terminus OATP PF03137.20 CDJ56752.1 - 9.6 4.4 10.2 2 6.6 4.3 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BUD22 PF09073.10 CDJ56753.1 - 0.057 12.8 21.1 0.062 12.6 21.1 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 CDJ56753.1 - 0.85 9.3 27.1 1.1 8.9 27.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAF1_ABF1 PF04684.13 CDJ56753.1 - 0.85 8.6 24.3 0.97 8.4 24.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SDA1 PF05285.12 CDJ56753.1 - 0.88 8.9 27.9 1.1 8.6 27.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDJ56753.1 - 2.9 6.0 30.2 3.3 5.8 30.2 1.1 1 0 0 1 1 1 0 Nop14-like family CAML PF14963.6 CDJ56753.1 - 3.7 7.6 12.1 4.8 7.2 12.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand RXLR PF16810.5 CDJ56753.1 - 9.6 6.6 17.3 0.36 11.3 3.3 2.2 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity RskA PF10099.9 CDJ56755.1 - 0.0016 18.8 9.8 0.0016 18.8 9.8 6.9 1 1 4 5 5 5 1 Anti-sigma-K factor rskA DUF155 PF02582.14 CDJ56756.1 - 0.00022 21.4 0.0 0.00027 21.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Phenol_Hydrox PF02332.18 CDJ56756.1 - 0.016 14.8 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase RskA PF10099.9 CDJ56757.1 - 1.3e-05 25.5 13.2 1.3e-05 25.5 13.2 24.6 6 5 10 16 16 16 2 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ56757.1 - 0.0038 16.9 14.1 0.0038 16.9 14.1 12.6 5 3 1 8 8 8 1 Exonuclease VII, large subunit Med15 PF09606.10 CDJ56758.1 - 0.00057 18.7 13.4 0.00057 18.7 13.4 4.0 2 1 1 3 3 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 CDJ56758.1 - 0.00089 19.3 11.4 0.00089 19.3 11.4 4.3 2 1 2 4 4 2 1 Suppressor of forked protein (Suf) Exonuc_VII_L PF02601.15 CDJ56758.1 - 0.0071 16.0 5.5 0.0071 16.0 5.5 3.3 2 2 0 2 2 1 1 Exonuclease VII, large subunit MarR PF01047.22 CDJ56758.1 - 0.058 13.3 1.8 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 MarR family Afi1 PF07792.12 CDJ56758.1 - 0.13 12.8 27.3 1.7 9.1 5.2 3.5 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SID-1_RNA_chan PF13965.6 CDJ56758.1 - 0.17 10.3 9.2 0.41 9.0 1.6 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 CDJ56758.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.1 1 1 0 2 2 1 0 N-glycosylation protein RNase_H2_suC PF08615.11 CDJ56758.1 - 0.21 11.7 19.0 1.3 9.2 0.8 3.2 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2052 PF09747.9 CDJ56758.1 - 0.31 11.2 36.4 0.77 9.8 7.5 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF4746 PF15928.5 CDJ56758.1 - 0.64 9.4 0.0 0.64 9.4 0.0 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4746) Connexin PF00029.19 CDJ56758.1 - 0.91 9.2 23.9 0.38 10.5 6.4 2.8 3 0 0 3 3 3 0 Connexin eIF-3_zeta PF05091.12 CDJ56758.1 - 1.2 8.0 38.0 0.027 13.4 8.2 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 CDJ56758.1 - 1.3 8.5 46.1 0.035 13.7 19.6 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ56758.1 - 1.7 8.1 33.3 0.97 8.8 8.4 3.0 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ56758.1 - 2.1 7.3 26.1 0.21 10.6 7.9 2.7 3 0 0 3 3 3 0 CLN3 protein DUF4820 PF16091.5 CDJ56758.1 - 5.1 6.4 30.5 0.53 9.6 8.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 CDJ56758.1 - 5.1 5.9 27.0 0.049 12.5 2.9 2.5 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 OATP PF03137.20 CDJ56758.1 - 5.7 5.1 20.5 2.2 6.5 3.3 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF5364 PF17322.2 CDJ56758.1 - 6.9 6.9 35.2 0.078 13.3 9.9 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5364) DUF1645 PF07816.11 CDJ56758.1 - 7.7 7.1 28.7 2.2 8.8 15.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) CDC45 PF02724.14 CDJ56758.1 - 7.8 4.7 29.1 0.41 8.9 3.2 2.6 3 0 0 3 3 3 0 CDC45-like protein RPN2_C PF18004.1 CDJ56758.1 - 8.5 6.3 35.6 0.77 9.7 12.9 3.3 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain GerA PF03323.13 CDJ56759.1 - 0.2 10.0 0.0 0.2 10.0 0.0 2.3 3 0 0 3 3 3 0 Bacillus/Clostridium GerA spore germination protein OTCace PF00185.24 CDJ56760.1 - 0.083 13.0 0.9 0.11 12.5 0.9 1.1 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DnaJ PF00226.31 CDJ56762.1 - 2e-14 53.5 0.1 2e-13 50.2 0.1 2.3 1 1 0 1 1 1 1 DnaJ domain AF-4 PF05110.13 CDJ56762.1 - 0.003 15.8 12.5 0.0037 15.5 12.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Lin-8 PF03353.15 CDJ56762.1 - 0.0097 15.5 5.9 0.012 15.2 5.9 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF5302 PF17227.2 CDJ56762.1 - 0.085 13.9 0.9 0.96 10.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5302) SR-25 PF10500.9 CDJ56762.1 - 0.48 10.0 24.0 1.1 8.8 24.1 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ56762.1 - 0.9 10.4 12.1 2.2 9.2 11.5 1.9 1 1 1 2 2 2 0 Chorion family 2 DUF4667 PF15700.5 CDJ56762.1 - 3.5 7.6 19.2 7.4 6.6 19.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) SUZ PF12752.7 CDJ56762.1 - 5 8.0 8.6 1.8 9.4 4.7 2.3 2 1 0 2 2 2 0 SUZ domain LRR_4 PF12799.7 CDJ56764.1 - 3e-16 59.2 3.6 5.9e-08 32.9 0.3 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ56764.1 - 3.7e-10 39.6 0.4 1.6e-07 31.0 0.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CDJ56764.1 - 5e-09 35.8 4.3 0.0013 18.5 0.1 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CDJ56764.1 - 0.0047 16.9 1.8 4.8 7.5 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ56764.1 - 0.015 15.7 2.0 14 6.7 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat AAA_5 PF07728.14 CDJ56765.1 - 0.023 14.7 0.6 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Spt20 PF12090.8 CDJ56765.1 - 0.094 12.3 0.0 0.094 12.3 0.0 6.3 6 0 0 6 6 6 0 Spt20 family AAA PF00004.29 CDJ56765.1 - 0.72 10.3 4.3 1.7 9.1 0.1 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CDJ56765.1 - 2.2 8.7 6.6 0.39 11.1 0.7 2.9 3 0 0 3 3 3 0 AAA C-terminal domain Med15 PF09606.10 CDJ56765.1 - 6.2 5.4 84.3 0.14 10.8 36.6 3.4 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_1 PF00076.22 CDJ56766.1 - 1.1e-09 37.9 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_7 PF14246.6 CDJ56766.1 - 0.0054 16.8 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TCTP PF00838.17 CDJ56766.1 - 4.5 7.6 7.7 1.5 9.2 0.7 2.3 2 0 0 2 2 2 0 Translationally controlled tumour protein RNA_pol_Rpb6 PF01192.22 CDJ56767.1 - 2.1e-18 66.0 0.0 3.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ribosomal_60s PF00428.19 CDJ56768.1 - 0.31 11.7 5.4 0.14 12.8 3.2 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein IHABP4_N PF16174.5 CDJ56768.1 - 0.7 10.5 10.0 0.87 10.2 10.0 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Spt20 PF12090.8 CDJ56768.1 - 0.91 9.1 18.6 0.16 11.6 14.2 1.7 2 0 0 2 2 2 0 Spt20 family Androgen_recep PF02166.16 CDJ56768.1 - 1.2 7.9 30.1 0.86 8.4 5.9 2.1 2 0 0 2 2 2 0 Androgen receptor RskA PF10099.9 CDJ56769.1 - 1.2e-05 25.7 0.2 1.2e-05 25.7 0.2 2.0 1 1 1 2 2 2 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ56769.1 - 2.1e-05 24.3 24.2 2.1e-05 24.3 24.2 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 CDJ56769.1 - 0.021 13.3 26.4 0.024 13.2 26.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 SPX PF03105.19 CDJ56769.1 - 0.061 13.2 27.9 0.075 12.9 27.9 1.1 1 0 0 1 1 1 0 SPX domain FAM117 PF15388.6 CDJ56769.1 - 0.42 10.0 32.0 0.56 9.6 32.0 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Apt1 PF10351.9 CDJ56769.1 - 0.81 8.5 26.4 1.5 7.6 26.4 1.4 1 1 0 1 1 1 0 Golgi-body localisation protein domain Coilin_N PF15862.5 CDJ56769.1 - 0.91 9.3 31.5 0.022 14.5 6.2 2.2 2 0 0 2 2 2 0 Coilin N-terminus GEMIN8 PF15348.6 CDJ56769.1 - 2.2 8.5 38.7 1 9.6 9.1 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 MID_MedPIWI PF18296.1 CDJ56769.1 - 7.5 6.3 27.0 0.14 12.0 9.4 2.1 2 0 0 2 2 2 0 MID domain of medPIWI Ribosomal_60s PF00428.19 CDJ56770.1 - 0.008 16.7 35.2 0.058 14.0 4.1 3.3 3 0 0 3 3 3 3 60s Acidic ribosomal protein SUIM_assoc PF16619.5 CDJ56770.1 - 0.014 15.4 13.1 0.038 14.0 5.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol_lambd_f PF10391.9 CDJ56771.1 - 0.00028 20.7 0.2 0.0012 18.6 0.2 2.2 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda SUIM_assoc PF16619.5 CDJ56771.1 - 0.00087 19.3 1.3 0.00087 19.3 1.3 8.9 4 2 2 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 HHH_8 PF14716.6 CDJ56771.1 - 0.0024 18.2 1.0 0.0024 18.2 1.0 5.0 5 0 0 5 5 5 2 Helix-hairpin-helix domain Ribosomal_60s PF00428.19 CDJ56771.1 - 0.011 16.2 4.4 0.011 16.2 4.4 15.8 8 4 5 14 14 14 0 60s Acidic ribosomal protein DUF3573 PF12097.8 CDJ56771.1 - 0.036 12.9 0.2 0.036 12.9 0.2 4.8 5 1 0 5 5 5 0 Protein of unknown function (DUF3573) NPR3 PF03666.13 CDJ56772.1 - 0.00027 19.9 5.8 0.00027 19.9 5.8 2.4 2 1 0 2 2 1 1 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ56772.1 - 0.00095 19.1 20.1 0.00095 19.1 20.1 2.7 2 1 0 2 2 1 1 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CDJ56772.1 - 0.0018 17.2 22.0 0.079 11.7 3.8 2.2 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein ESM4 PF15952.5 CDJ56772.1 - 0.0033 17.9 17.3 0.0033 17.9 17.3 2.7 2 1 0 2 2 1 1 Enhancer of split M4 family SprA-related PF12118.8 CDJ56772.1 - 0.0033 16.6 45.9 0.0033 16.6 45.9 3.6 3 1 1 4 4 2 1 SprA-related family DUF2828 PF11443.8 CDJ56772.1 - 0.0039 15.4 24.2 0.068 11.3 13.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2828) Cwf_Cwc_15 PF04889.12 CDJ56772.1 - 0.0047 16.7 36.9 0.13 11.9 13.1 2.4 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein BORG_CEP PF14957.6 CDJ56772.1 - 0.026 15.7 10.2 0.026 15.7 10.2 2.7 2 1 0 2 2 1 0 Cdc42 effector AF-4 PF05110.13 CDJ56772.1 - 0.042 11.9 48.2 0.12 10.5 18.6 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Apt1 PF10351.9 CDJ56772.1 - 0.061 12.2 29.1 0.55 9.0 6.9 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4746 PF15928.5 CDJ56772.1 - 0.11 11.9 26.9 0.055 12.9 13.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 CDJ56772.1 - 0.17 12.2 42.9 0.17 12.2 20.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.12 CDJ56772.1 - 0.2 11.9 28.5 0.019 15.2 11.8 2.9 3 0 0 3 3 3 0 GAGA binding protein-like family SDA1 PF05285.12 CDJ56772.1 - 0.37 10.2 42.2 1 8.8 14.8 2.2 2 0 0 2 2 2 0 SDA1 RAP1 PF07218.11 CDJ56772.1 - 0.37 9.0 24.1 0.11 10.8 8.1 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) TT_ORF1 PF02956.14 CDJ56772.1 - 0.38 9.4 17.4 0.64 8.6 9.2 2.2 2 0 0 2 2 2 0 TT viral orf 1 CNDH2_C PF16858.5 CDJ56772.1 - 0.39 10.5 33.9 0.38 10.6 15.6 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Peptidase_U57 PF05582.12 CDJ56772.1 - 0.75 9.0 21.5 1.5 8.0 4.4 2.4 2 0 0 2 2 2 0 YabG peptidase U57 CDC45 PF02724.14 CDJ56772.1 - 0.93 7.7 34.8 0.061 11.6 13.4 2.1 2 0 0 2 2 2 0 CDC45-like protein O-antigen_lig PF13425.6 CDJ56772.1 - 1.1 7.9 17.9 0.015 14.1 5.1 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Rrn6 PF10214.9 CDJ56772.1 - 1.4 7.3 46.9 1 7.8 15.7 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RskA PF10099.9 CDJ56772.1 - 1.4 9.1 78.1 0.065 13.5 8.5 5.5 1 1 2 3 3 2 0 Anti-sigma-K factor rskA Smg8_Smg9 PF10220.9 CDJ56772.1 - 1.6 7.0 35.7 0.057 11.7 10.3 2.2 2 0 0 2 2 2 0 Smg8_Smg9 SLC12 PF03522.15 CDJ56772.1 - 2.9 6.8 45.7 0.45 9.5 17.9 2.2 2 0 0 2 2 2 0 Solute carrier family 12 V_ATPase_I PF01496.19 CDJ56772.1 - 3.7 5.3 33.2 0.05 11.5 15.5 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase_fungal PF17667.1 CDJ56772.1 - 3.8 6.2 25.1 0.7 8.6 7.3 2.1 2 0 0 2 2 2 0 Fungal protein kinase TRAP_alpha PF03896.16 CDJ56772.1 - 4.4 6.4 18.9 3.6 6.7 0.5 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RCR PF12273.8 CDJ56772.1 - 5.4 7.7 27.3 0.99 10.1 10.2 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MMR1 PF08505.10 CDJ56772.1 - 7.5 6.8 45.0 1.7 8.9 18.4 2.7 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein LMBR1 PF04791.16 CDJ56772.1 - 9.1 5.0 19.4 5.1 5.9 4.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Spt20 PF12090.8 CDJ56773.1 - 2.7 7.6 21.4 0.058 13.0 12.3 2.1 2 0 0 2 2 2 0 Spt20 family Kinesin PF00225.23 CDJ56774.1 - 2.4e-18 66.2 10.5 3.7e-18 65.6 0.0 3.3 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ56774.1 - 3.1e-13 49.9 0.0 9.6e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding EF-hand_8 PF13833.6 CDJ56775.1 - 0.18 11.7 0.0 14 5.7 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair TFIIA PF03153.13 CDJ56776.1 - 0.32 10.9 25.2 0.46 10.4 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2489 PF10675.9 CDJ56776.1 - 0.51 10.2 7.5 2.9 7.8 8.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) CcmD PF04995.14 CDJ56777.1 - 0.81 9.8 8.2 1.5 8.9 8.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) YajC PF02699.15 CDJ56777.1 - 1.1 9.2 6.2 1.7 8.6 6.2 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit WBP-1 PF11669.8 CDJ56777.1 - 1.2 9.8 2.6 8.2 7.1 0.1 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Herpes_capsid PF06112.11 CDJ56779.1 - 8.1 6.5 16.2 11 6.0 16.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RskA PF10099.9 CDJ56780.1 - 0.082 13.2 0.0 0.082 13.2 0.0 4.0 3 3 0 3 3 3 0 Anti-sigma-K factor rskA RabGAP-TBC PF00566.18 CDJ56781.1 - 1e-16 61.3 0.0 1e-16 61.3 0.0 2.4 1 1 0 2 2 2 1 Rab-GTPase-TBC domain Ndc1_Nup PF09531.10 CDJ56781.1 - 0.0081 14.9 1.5 0.0078 15.0 1.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Velvet PF11754.8 CDJ56781.1 - 0.012 15.6 3.5 0.014 15.4 3.5 1.2 1 0 0 1 1 1 0 Velvet factor XRCC4 PF06632.12 CDJ56781.1 - 0.014 14.3 5.6 0.019 13.9 5.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 AUX_IAA PF02309.16 CDJ56781.1 - 0.025 14.4 2.4 0.033 14.0 2.4 1.1 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.13 CDJ56781.1 - 0.026 14.6 15.4 0.032 14.2 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CDJ56781.1 - 0.062 12.4 13.9 0.086 11.9 13.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X SprA-related PF12118.8 CDJ56781.1 - 0.065 12.4 15.4 0.093 11.9 15.4 1.2 1 0 0 1 1 1 0 SprA-related family Activator_LAG-3 PF11498.8 CDJ56781.1 - 0.07 12.1 17.1 0.11 11.5 17.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.14 CDJ56781.1 - 0.096 12.7 6.8 0.11 12.4 6.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SART-1 PF03343.13 CDJ56781.1 - 0.1 11.1 4.9 0.13 10.8 4.9 1.0 1 0 0 1 1 1 0 SART-1 family Peptidase_S64 PF08192.11 CDJ56781.1 - 0.11 11.0 7.6 0.13 10.7 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CDJ56781.1 - 0.11 11.3 5.8 0.13 11.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CDJ56781.1 - 0.14 11.3 0.7 0.16 11.1 0.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ATG2_CAD PF13329.6 CDJ56781.1 - 0.31 10.8 4.8 1.2 8.8 4.8 2.1 1 1 0 1 1 1 0 Autophagy-related protein 2 CAD motif PIP5K PF01504.18 CDJ56781.1 - 0.39 9.9 4.4 0.56 9.4 4.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TCP PF03634.13 CDJ56781.1 - 0.39 11.3 9.0 0.58 10.7 9.0 1.2 1 0 0 1 1 1 0 TCP family transcription factor DUF1645 PF07816.11 CDJ56781.1 - 0.61 10.6 9.4 0.89 10.1 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) SWI-SNF_Ssr4 PF08549.10 CDJ56781.1 - 0.68 8.5 9.3 0.86 8.2 9.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Apt1 PF10351.9 CDJ56781.1 - 3.2 6.5 12.1 4.2 6.1 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.17 CDJ56781.1 - 9 6.4 10.7 18 5.4 10.7 1.4 1 1 0 1 1 1 0 DDHD domain ERCC3_RAD25_C PF16203.5 CDJ56782.1 - 2.5e-79 266.0 10.0 2.9e-65 219.9 0.0 2.8 2 1 1 3 3 3 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CDJ56782.1 - 6.6e-14 52.3 1.3 9.5e-14 51.8 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ56782.1 - 1.1e-08 35.4 0.1 8.2e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDJ56782.1 - 1.7e-06 27.0 0.0 5.3e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain TFIIA PF03153.13 CDJ56782.1 - 0.14 12.2 21.6 0.24 11.4 12.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LapA_dom PF06305.11 CDJ56784.1 - 0.17 11.7 1.6 9.7 6.1 0.1 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Spt20 PF12090.8 CDJ56784.1 - 0.24 11.0 6.5 0.34 10.5 6.5 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ56785.1 - 0.013 15.5 6.4 0.017 15.2 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF981 PF06168.11 CDJ56785.1 - 0.11 12.4 5.3 0.14 12.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF981) SUIM_assoc PF16619.5 CDJ56785.1 - 2.5 8.2 18.0 1.2 9.3 3.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MetRS-N PF09635.10 CDJ56786.1 - 0.017 15.6 0.3 0.027 15.0 0.3 1.4 1 0 0 1 1 1 0 MetRS-N binding domain eIF-5_eIF-2B PF01873.17 CDJ56787.1 - 5.8e-35 119.7 0.2 1.2e-34 118.7 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CDJ56787.1 - 2e-05 24.7 0.1 6e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Chorion_2 PF03964.15 CDJ56787.1 - 0.0047 17.7 5.0 0.01 16.7 5.0 1.6 1 0 0 1 1 1 1 Chorion family 2 PIP5K PF01504.18 CDJ56787.1 - 0.0091 15.3 0.7 0.016 14.5 0.7 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SPX PF03105.19 CDJ56787.1 - 0.021 14.8 10.9 0.027 14.4 10.9 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ56787.1 - 0.13 11.1 9.0 0.17 10.7 9.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3123 PF11321.8 CDJ56787.1 - 0.4 11.4 3.1 0.88 10.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) MSA-2c PF12238.8 CDJ56787.1 - 1 9.4 8.1 1.7 8.6 7.1 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c SARAF PF06682.12 CDJ56787.1 - 1.3 8.6 9.9 2.1 7.9 9.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4667 PF15700.5 CDJ56787.1 - 3 7.9 19.7 5.2 7.1 19.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) Secretin_N_2 PF07655.13 CDJ56787.1 - 6.8 7.3 21.1 0.46 11.1 12.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Herpes_LMP2 PF07415.11 CDJ56788.1 - 9.3 4.9 6.3 19 3.9 6.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein SpoIIIAH PF12685.7 CDJ56789.1 - 0.00057 19.8 4.5 0.00057 19.8 4.5 2.0 2 0 0 2 2 1 1 SpoIIIAH-like protein Caldesmon PF02029.15 CDJ56789.1 - 0.0035 16.2 15.8 0.0035 16.2 15.8 1.8 3 0 0 3 3 3 1 Caldesmon SPX PF03105.19 CDJ56789.1 - 0.008 16.1 14.4 2.8 7.8 13.3 2.5 2 1 0 2 2 2 2 SPX domain V_ATPase_I PF01496.19 CDJ56789.1 - 0.023 12.6 10.2 0.039 11.9 10.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ56789.1 - 0.037 14.0 15.3 0.1 12.6 15.3 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KCT2 PF17818.1 CDJ56789.1 - 0.057 13.5 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Keratinocyte-associated gene product Mucin PF01456.17 CDJ56789.1 - 0.3 11.1 0.1 0.3 11.1 0.1 2.3 3 0 0 3 3 2 0 Mucin-like glycoprotein DUF4834 PF16118.5 CDJ56789.1 - 0.35 11.9 0.1 0.35 11.9 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) O-antigen_lig PF13425.6 CDJ56789.1 - 1 8.0 3.0 1.8 7.3 3.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hid1 PF12722.7 CDJ56789.1 - 1.4 7.0 13.6 2.2 6.3 13.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2828 PF11443.8 CDJ56789.1 - 1.7 6.7 8.3 3 5.8 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Eapp_C PF10238.9 CDJ56789.1 - 1.9 8.6 12.9 1.5 8.9 6.1 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4551 PF15087.6 CDJ56789.1 - 4 6.1 18.5 0.052 12.4 9.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) TERB2 PF15101.6 CDJ56789.1 - 4.9 7.2 18.1 0.71 9.9 5.8 2.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 XRN_M PF17846.1 CDJ56789.1 - 5.2 5.9 10.6 10 5.0 10.6 1.4 1 0 0 1 1 1 0 Xrn1 helical domain GAGA_bind PF06217.12 CDJ56789.1 - 5.3 7.2 12.7 9.6 6.4 12.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 CDJ56789.1 - 5.5 5.9 15.1 9.8 5.1 15.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 FYDLN_acid PF09538.10 CDJ56789.1 - 5.6 7.7 15.9 2.5 8.8 8.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Menin PF05053.13 CDJ56789.1 - 9.1 4.5 8.6 22 3.2 8.6 1.6 1 0 0 1 1 1 0 Menin RAB3GAP2_C PF14656.6 CDJ56789.1 - 9.9 4.3 11.0 0.23 9.6 3.5 1.8 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Methyltransf_16 PF10294.9 CDJ56790.1 - 7.5e-12 45.3 0.0 2.1e-06 27.6 0.0 3.7 4 1 0 4 4 4 2 Lysine methyltransferase Mob1_phocein PF03637.17 CDJ56791.1 - 3.5e-25 89.0 1.1 5.2e-16 59.1 0.7 2.4 2 0 0 2 2 2 2 Mob1/phocein family DUF3405 PF11885.8 CDJ56791.1 - 0.0013 17.4 0.9 0.0016 17.1 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) CPSF100_C PF13299.6 CDJ56791.1 - 0.25 11.5 6.1 0.46 10.6 6.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal G0-G1_switch_2 PF15103.6 CDJ56791.1 - 0.37 11.2 4.9 0.92 10.0 4.9 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 RED_N PF07808.13 CDJ56791.1 - 0.64 9.6 15.2 1 8.9 15.2 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region CLN3 PF02487.17 CDJ56791.1 - 1.5 7.8 4.2 2.1 7.3 4.2 1.2 1 0 0 1 1 1 0 CLN3 protein Orf78 PF06024.12 CDJ56791.1 - 2 8.8 4.5 4.2 7.7 4.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) FUSC-like PF12805.7 CDJ56791.1 - 2.3 7.2 16.6 3.5 6.6 16.6 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS SpoIIP PF07454.11 CDJ56791.1 - 3.8 6.9 10.9 5.9 6.3 10.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ56791.1 - 5.1 5.9 13.9 6.9 5.5 13.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ56791.1 - 5.3 6.9 27.6 8.3 6.3 27.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 CDJ56792.1 - 2.7e-20 72.7 0.0 3.4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein GCP_C_terminal PF04130.13 CDJ56793.1 - 4.5e-15 55.9 25.0 4.5e-15 55.9 25.0 2.8 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal VHS PF00790.19 CDJ56794.1 - 9.9e-10 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain AAA_23 PF13476.6 CDJ56794.1 - 0.32 11.5 17.5 9 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CDJ56795.1 - 0.0048 17.0 40.4 0.0048 17.0 40.4 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit M_domain PF12938.7 CDJ56795.1 - 0.19 11.5 7.0 0.5 10.1 7.0 1.7 1 0 0 1 1 1 0 M domain of GW182 MFS_1 PF07690.16 CDJ56796.1 - 1.9e-36 125.7 25.4 5.1e-30 104.6 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ56796.1 - 1.1e-06 27.8 9.2 1.1e-06 27.8 9.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CDJ56796.1 - 0.055 12.3 9.6 0.14 11.0 9.6 1.7 1 1 0 1 1 1 0 MFS_1 like family Phasin PF05597.11 CDJ56801.1 - 0.044 13.8 0.1 0.044 13.8 0.1 3.7 4 1 1 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) G6PD_N PF00479.22 CDJ56801.1 - 0.066 13.8 2.2 0.08 13.6 0.3 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Drf_FH3 PF06367.16 CDJ56801.1 - 0.085 12.5 0.3 0.25 10.9 0.3 1.8 1 0 0 1 1 1 0 Diaphanous FH3 Domain BORCS8 PF10167.9 CDJ56801.1 - 0.12 12.4 2.2 2 8.4 0.2 3.2 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 PAS_10 PF13596.6 CDJ56801.1 - 0.18 12.4 0.0 8 7.1 0.0 2.8 2 1 0 2 2 2 0 PAS domain WXG100 PF06013.12 CDJ56801.1 - 0.37 11.0 12.6 0.28 11.4 0.2 4.5 2 2 2 4 4 4 0 Proteins of 100 residues with WXG TraG_N PF07916.11 CDJ56801.1 - 0.53 9.1 7.1 1.5 7.6 0.9 2.2 2 0 0 2 2 2 0 TraG-like protein, N-terminal region T7SS_ESX_EspC PF10824.8 CDJ56801.1 - 4.1 7.9 23.3 0.48 10.9 1.2 4.7 3 3 2 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm DUF1993 PF09351.10 CDJ56801.1 - 5.6 7.1 8.9 6.1 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) BUD22 PF09073.10 CDJ56802.1 - 0.004 16.6 0.8 0.005 16.3 0.8 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 CDJ56802.1 - 0.037 14.0 2.1 0.048 13.7 2.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SERTA PF06031.13 CDJ56802.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SERTA motif BAR_3_WASP_bdg PF10456.9 CDJ56803.1 - 0.024 14.1 1.7 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Sec34 PF04136.15 CDJ56803.1 - 0.058 13.3 0.7 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Sec34-like family DUF572 PF04502.13 CDJ56803.1 - 0.5 9.9 8.8 0.035 13.7 3.9 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) KELK PF15796.5 CDJ56803.1 - 6.3 7.3 10.3 0.67 10.5 4.2 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PFEMP PF03011.15 CDJ56803.1 - 7.4 7.2 6.7 1.5 9.5 1.8 2.0 2 0 0 2 2 2 0 PFEMP DBL domain RNase_T PF00929.24 CDJ56804.1 - 4.1e-09 37.2 0.0 7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 CDJ56804.1 - 8.5e-06 25.6 0.0 8.5e-06 25.6 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DDHD PF02862.17 CDJ56804.1 - 0.0042 17.3 11.2 0.0046 17.2 0.7 2.9 3 0 0 3 3 3 2 DDHD domain DUF2370 PF10176.9 CDJ56804.1 - 1.3 8.6 5.6 0.72 9.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2151 PF10221.9 CDJ56804.1 - 4.2 5.8 9.2 0.29 9.7 3.4 1.8 2 0 0 2 2 2 0 Cell cycle and development regulator SAPS PF04499.15 CDJ56804.1 - 5.3 5.7 10.6 0.85 8.3 5.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 CDJ56804.1 - 5.6 5.6 21.5 0.018 13.9 7.4 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EPL1 PF10513.9 CDJ56804.1 - 5.8 7.3 24.3 0.067 13.6 6.9 3.0 3 0 0 3 3 3 0 Enhancer of polycomb-like CNDH2_C PF16858.5 CDJ56804.1 - 6.5 6.5 20.8 2.7 7.8 14.2 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Presenilin PF01080.17 CDJ56804.1 - 9.1 4.9 32.4 0.25 10.1 15.9 2.7 3 0 0 3 3 3 0 Presenilin VRR_NUC PF08774.11 CDJ56807.1 - 3.5e-10 39.9 9.4 2.7e-09 37.0 9.4 2.7 1 0 0 1 1 1 1 VRR-NUC domain SUIM_assoc PF16619.5 CDJ56807.1 - 0.0042 17.1 0.5 0.0042 17.1 0.5 15.4 12 4 0 12 12 12 5 Unstructured region C-term to UIM in Ataxin3 Coilin_N PF15862.5 CDJ56807.1 - 0.15 11.9 0.1 0.15 11.9 0.1 9.7 8 2 2 10 10 10 0 Coilin N-terminus GETHR PF05671.11 CDJ56808.1 - 5.9e-08 31.9 2.2 0.088 12.2 0.3 3.6 2 1 1 3 3 3 3 GETHR pentapeptide repeat (5 copies) Methyltr_RsmF_N PF17125.5 CDJ56808.1 - 3e-07 30.8 0.0 5.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF SR-25 PF10500.9 CDJ56808.1 - 0.006 16.2 6.0 0.006 16.2 6.0 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CDJ56808.1 - 0.12 13.2 14.2 0.65 10.9 5.7 2.5 2 0 0 2 2 2 0 Chorion family 2 BUD22 PF09073.10 CDJ56808.1 - 0.15 11.4 41.5 0.98 8.7 30.4 2.1 2 0 0 2 2 2 0 BUD22 DUF3446 PF11928.8 CDJ56808.1 - 0.16 12.3 12.4 0.14 12.5 3.7 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain TRAPPC9-Trs120 PF08626.11 CDJ56808.1 - 0.21 8.9 0.5 0.28 8.5 0.5 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ipi1_N PF12333.8 CDJ56808.1 - 1.6 9.4 5.1 0.58 10.8 0.4 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Nop14 PF04147.12 CDJ56808.1 - 4.2 5.5 30.7 4.5 5.4 24.2 2.1 2 0 0 2 2 2 0 Nop14-like family cEGF PF12662.7 CDJ56812.1 - 5e-10 39.1 21.9 0.00055 19.8 0.5 3.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDJ56812.1 - 1.2e-09 38.3 19.7 1.5e-05 25.2 0.4 3.4 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDJ56812.1 - 5.4e-09 36.1 23.2 1.8e-05 24.8 0.6 4.7 5 0 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.27 CDJ56812.1 - 6.5e-06 26.3 18.7 0.0017 18.6 0.5 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 CDJ56812.1 - 2.9e-05 24.1 6.9 0.0061 16.7 0.1 3.4 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 CDJ56812.1 - 0.00013 22.5 20.4 0.0022 18.5 1.6 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF Exonuc_VII_L PF02601.15 CDJ56812.1 - 0.0017 18.0 6.2 0.0017 18.0 6.2 4.4 2 1 1 3 3 3 1 Exonuclease VII, large subunit RANK_CRD_2 PF18278.1 CDJ56812.1 - 0.0064 16.6 5.4 1.4 9.2 0.9 3.3 3 0 0 3 3 3 2 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Plasmod_Pvs28 PF06247.11 CDJ56812.1 - 0.038 14.3 18.2 0.4 11.0 3.8 3.8 4 0 0 4 4 4 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CDJ56812.1 - 0.05 13.7 12.5 2.4 8.3 0.1 3.4 3 0 0 3 3 3 0 MSP1 EGF domain 1 BCAS2 PF05700.11 CDJ56813.1 - 4e-08 33.2 0.2 9.3e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MitoNEET_N PF10660.9 CDJ56813.1 - 0.22 11.6 1.5 0.68 10.0 1.5 1.8 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus PIG-L PF02585.17 CDJ56814.1 - 2e-13 51.1 0.0 2e-11 44.6 0.0 2.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase YebO PF13974.6 CDJ56814.1 - 0.19 11.8 1.9 0.4 10.8 1.9 1.5 1 0 0 1 1 1 0 YebO-like protein CS PF04969.16 CDJ56815.1 - 3.6e-05 24.7 0.0 0.00047 21.1 0.0 2.3 1 1 0 1 1 1 1 CS domain CDC37_N PF03234.14 CDJ56815.1 - 0.0068 17.3 2.5 0.0068 17.3 2.5 3.8 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding SR-25 PF10500.9 CDJ56815.1 - 5.4 6.5 33.9 0.02 14.5 4.9 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ56815.1 - 7.9 4.4 23.8 0.26 9.3 8.5 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein COX2 PF00116.20 CDJ56816.1 - 4e-43 146.1 0.0 5.8e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain tRNA-synt_2e PF02091.15 CDJ56816.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Arf PF00025.21 CDJ56817.1 - 4.9e-76 254.1 0.0 5.7e-76 253.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ56817.1 - 2.5e-14 53.5 0.0 3.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDJ56817.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDJ56817.1 - 2.4e-12 46.7 1.1 2.2e-08 33.7 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDJ56817.1 - 4e-12 46.0 0.0 5.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ56817.1 - 3.1e-09 36.5 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ56817.1 - 2.5e-05 24.3 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDJ56817.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PGM_PMM_III PF02880.16 CDJ56818.1 - 3.7e-27 94.8 0.0 9.9e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 CDJ56818.1 - 9.7e-26 90.1 0.0 1.8e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDJ56818.1 - 8.9e-11 42.3 0.0 3.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CDJ56818.1 - 0.0011 19.1 0.0 0.005 17.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SUIM_assoc PF16619.5 CDJ56819.1 - 0.041 14.0 0.0 0.041 14.0 0.0 13.1 6 5 2 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 BAF1_ABF1 PF04684.13 CDJ56820.1 - 1.6e-05 24.2 0.8 2.2e-05 23.7 0.8 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Cob_adeno_trans PF01923.18 CDJ56820.1 - 0.0055 16.9 10.0 0.14 12.3 4.5 2.2 2 0 0 2 2 2 2 Cobalamin adenosyltransferase RACo_C_ter PF14574.6 CDJ56820.1 - 0.0064 15.6 0.4 0.013 14.6 0.4 1.6 1 0 0 1 1 1 1 C-terminal domain of RACo the ASKHA domain Ribosomal_60s PF00428.19 CDJ56820.1 - 0.25 12.0 14.8 0.66 10.6 12.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ56820.1 - 0.26 11.3 39.6 1.4 8.9 23.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ56820.1 - 0.82 9.9 35.7 0.12 12.7 13.4 3.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ56820.1 - 0.95 9.9 16.4 3.4 8.1 16.4 2.0 1 1 0 1 1 1 0 AAA domain Med15 PF09606.10 CDJ56820.1 - 1.7 7.2 44.6 0.11 11.1 23.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1863 PF08937.11 CDJ56820.1 - 2 8.7 5.5 2.5 8.4 1.8 2.2 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF2275 PF10039.9 CDJ56820.1 - 2.3 8.3 11.5 8.3 6.4 11.5 1.9 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2275) PCRF PF03462.18 CDJ56820.1 - 2.3 8.0 13.6 1.5 8.7 11.2 1.8 2 0 0 2 2 2 0 PCRF domain Dsh_C PF12316.8 CDJ56820.1 - 8.4 6.7 12.5 0.35 11.2 3.7 2.4 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Sad1_UNC PF07738.13 CDJ56821.1 - 5.2e-12 45.9 0.5 4e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal LAMTOR PF15454.6 CDJ56821.1 - 0.052 14.2 2.4 0.052 14.2 2.4 2.9 3 1 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF1091 PF06477.13 CDJ56821.1 - 0.06 13.8 0.0 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) LAGLIDADG_2 PF03161.13 CDJ56821.1 - 0.08 13.0 1.5 0.46 10.5 1.5 1.9 1 1 0 1 1 1 0 LAGLIDADG DNA endonuclease family Suf PF05843.14 CDJ56821.1 - 0.16 12.0 8.3 0.23 11.4 8.3 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CDJ56821.1 - 9.9 6.0 14.5 16 5.3 14.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 CDJ56822.1 - 0.00017 21.3 0.4 0.088 12.9 0.2 4.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 CDJ56822.1 - 0.0055 17.1 0.4 0.0055 17.1 0.4 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Adaptin_binding PF10199.9 CDJ56822.1 - 0.091 13.4 0.0 0.091 13.4 0.0 7.4 4 3 1 5 5 5 0 Alpha and gamma adaptin binding protein p34 Shadoo PF14999.6 CDJ56825.1 - 0.0093 16.1 1.0 0.015 15.4 1.0 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective PSII_Pbs27 PF13326.6 CDJ56825.1 - 0.026 14.9 0.8 0.051 13.9 0.8 1.6 1 1 0 1 1 1 0 Photosystem II Pbs27 RskA PF10099.9 CDJ56826.1 - 0.00052 20.4 1.0 0.00052 20.4 1.0 6.7 4 2 1 5 5 5 2 Anti-sigma-K factor rskA BUD22 PF09073.10 CDJ56828.1 - 0.18 11.1 32.8 0.0088 15.4 25.6 1.8 1 1 1 2 2 2 0 BUD22 GREB1 PF15782.5 CDJ56828.1 - 0.34 8.0 22.3 0.44 7.6 22.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2232 PF09991.9 CDJ56828.1 - 0.74 8.9 1.4 1.1 8.4 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DivIVA PF05103.13 CDJ56828.1 - 1.2 9.2 32.0 0.086 12.9 8.9 4.1 2 1 1 3 3 3 0 DivIVA protein TFIIA PF03153.13 CDJ56828.1 - 6.4 6.7 43.0 15 5.5 43.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ56830.1 - 2.8e-07 30.4 7.4 2.8e-07 30.4 7.4 8.2 5 2 2 7 7 7 1 Nuclear RNA-splicing-associated protein Ribosomal_L27A PF00828.19 CDJ56830.1 - 0.0068 17.1 0.0 0.022 15.4 0.0 1.9 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RskA PF10099.9 CDJ56830.1 - 0.026 14.8 0.0 0.026 14.8 0.0 9.1 3 3 2 5 5 5 0 Anti-sigma-K factor rskA Memo PF01875.17 CDJ56831.1 - 6.8e-54 182.8 0.0 8.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF4345 PF14248.6 CDJ56832.1 - 0.018 14.9 0.8 0.05 13.5 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) PAT1 PF09770.9 CDJ56832.1 - 0.39 8.9 73.6 0.014 13.7 47.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.12 CDJ56832.1 - 9.9 4.7 49.5 0.13 10.9 31.3 2.1 2 0 0 2 2 2 0 Hamartin protein SR-25 PF10500.9 CDJ56834.1 - 0.019 14.6 0.9 0.023 14.3 0.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EP400_N PF15790.5 CDJ56834.1 - 0.036 12.9 0.7 0.044 12.6 0.7 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal SLX9 PF15341.6 CDJ56834.1 - 0.046 14.1 4.2 0.072 13.5 4.2 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 AP2 PF00847.20 CDJ56835.1 - 1.6e-05 25.1 1.5 1.6e-05 25.1 1.5 6.3 6 1 0 6 6 6 3 AP2 domain DUF4667 PF15700.5 CDJ56835.1 - 0.0079 16.3 6.5 0.0079 16.3 6.5 8.5 6 1 0 6 6 6 4 Domain of unknown function (DUF4667) FUSC PF04632.12 CDJ56836.1 - 0.14 10.7 22.0 0.17 10.4 22.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PhageMin_Tail PF10145.9 CDJ56836.1 - 0.99 9.2 10.7 2 8.2 10.7 1.5 1 0 0 1 1 1 0 Phage-related minor tail protein ALMT PF11744.8 CDJ56836.1 - 2.5 6.9 20.5 2.9 6.6 20.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 CDJ56836.1 - 8.8 5.8 37.1 15 5.0 37.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Shadoo PF14999.6 CDJ56838.1 - 0.0052 16.9 7.8 0.0052 16.9 7.8 1.5 2 0 0 2 2 2 1 Shadow of prion protein, neuroprotective Cpn60_TCP1 PF00118.24 CDJ56839.1 - 2.7e-13 49.4 0.2 2.8e-13 49.3 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpc4 PF05132.14 CDJ56841.1 - 0.00016 22.1 4.4 0.00024 21.6 4.4 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF2052 PF09747.9 CDJ56841.1 - 0.00023 21.4 25.0 0.0003 21.0 25.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Merozoite_SPAM PF07133.11 CDJ56841.1 - 0.00023 21.2 47.1 0.0003 20.8 47.1 1.1 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Mpp10 PF04006.12 CDJ56841.1 - 0.0004 19.0 27.8 0.00047 18.8 27.8 1.0 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 CDJ56841.1 - 0.00066 18.0 28.5 0.00079 17.8 28.5 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 CDJ56841.1 - 0.0011 18.4 24.0 0.0014 18.1 24.0 1.1 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 CDJ56841.1 - 0.0017 16.7 21.5 0.002 16.5 21.5 1.0 1 0 0 1 1 1 1 CDC45-like protein CCDC106 PF15794.5 CDJ56841.1 - 0.0051 16.5 14.2 0.0069 16.1 14.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 CLN3 PF02487.17 CDJ56841.1 - 0.0054 15.8 1.4 0.0061 15.6 1.4 1.1 1 0 0 1 1 1 1 CLN3 protein DUF3381 PF11861.8 CDJ56841.1 - 0.0066 16.3 31.5 0.0094 15.8 31.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) RRN3 PF05327.11 CDJ56841.1 - 0.01 14.4 16.2 0.013 14.1 16.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDJ56841.1 - 0.016 13.4 28.9 0.019 13.1 28.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Caldesmon PF02029.15 CDJ56841.1 - 0.031 13.0 31.8 0.036 12.8 31.8 1.0 1 0 0 1 1 1 0 Caldesmon DUF5308 PF17233.2 CDJ56841.1 - 0.041 14.1 1.9 0.05 13.8 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DDHD PF02862.17 CDJ56841.1 - 0.053 13.7 4.5 0.08 13.1 4.5 1.4 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.11 CDJ56841.1 - 0.062 13.2 11.0 0.095 12.6 11.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SpoIIP PF07454.11 CDJ56841.1 - 0.067 12.6 19.7 0.087 12.3 19.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 CDJ56841.1 - 0.075 12.4 29.9 0.1 12.0 29.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.6 CDJ56841.1 - 0.084 11.6 9.6 0.096 11.4 9.6 1.1 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 CDJ56841.1 - 0.091 12.2 35.2 0.12 11.8 35.2 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 CDJ56841.1 - 0.11 11.2 8.6 0.13 11.0 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CDJ56841.1 - 0.11 11.4 10.3 0.15 11.0 10.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 CDJ56841.1 - 0.13 11.4 15.0 0.21 10.8 15.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 CDJ56841.1 - 0.14 10.9 20.7 0.2 10.4 20.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ56841.1 - 0.17 10.6 15.2 0.21 10.3 15.2 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 CDJ56841.1 - 0.2 11.8 17.6 0.24 11.5 17.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CCDC53 PF10152.9 CDJ56841.1 - 0.22 11.9 12.5 0.31 11.5 12.5 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex YL1 PF05764.13 CDJ56841.1 - 0.24 11.5 35.1 0.38 10.8 35.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC27 PF09507.10 CDJ56841.1 - 0.3 10.4 26.9 0.35 10.2 26.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF262 PF03235.14 CDJ56841.1 - 0.31 11.2 9.2 0.38 10.9 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Serinc PF03348.15 CDJ56841.1 - 0.41 9.5 3.3 0.51 9.2 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3807 PF12720.7 CDJ56841.1 - 0.47 10.7 22.6 0.57 10.4 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Paf1 PF03985.13 CDJ56841.1 - 0.48 9.4 36.7 0.65 8.9 36.7 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 CDJ56841.1 - 0.5 10.1 28.9 0.65 9.8 28.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 CDJ56841.1 - 0.57 8.7 39.7 0.79 8.2 39.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 CDJ56841.1 - 0.58 9.1 13.6 0.7 8.9 13.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ56841.1 - 0.7 8.2 5.1 0.85 8.0 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4045 PF13254.6 CDJ56841.1 - 0.92 9.1 15.9 1.1 8.8 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5523 PF17661.1 CDJ56841.1 - 0.98 9.1 31.4 1.9 8.1 31.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ureide_permease PF07168.11 CDJ56841.1 - 1 8.0 7.7 1.4 7.6 7.7 1.1 1 0 0 1 1 1 0 Ureide permease Nop53 PF07767.11 CDJ56841.1 - 1.2 8.5 37.7 1.7 8.0 37.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4484 PF14831.6 CDJ56841.1 - 1.4 8.9 13.9 2.4 8.1 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) FAM60A PF15396.6 CDJ56841.1 - 1.5 8.8 14.2 1.9 8.4 14.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_C37 PF05416.12 CDJ56841.1 - 1.5 7.2 9.3 1.9 6.9 9.3 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4746 PF15928.5 CDJ56841.1 - 2 7.8 29.8 2.6 7.4 29.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LAP1C PF05609.12 CDJ56841.1 - 2 7.4 13.9 2.3 7.2 13.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Gti1_Pac2 PF09729.9 CDJ56841.1 - 2.3 8.3 14.8 3.2 7.8 14.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family MCM_bind PF09739.9 CDJ56841.1 - 2.3 6.6 15.5 2.8 6.3 15.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 CDJ56841.1 - 2.4 6.8 17.5 3 6.5 17.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GET2 PF08690.10 CDJ56841.1 - 2.6 7.6 11.8 3.3 7.3 11.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 CDJ56841.1 - 2.6 8.0 7.1 3.2 7.8 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.12 CDJ56841.1 - 2.8 8.2 10.6 3.4 7.9 10.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.12 CDJ56841.1 - 2.9 7.2 21.9 3.7 6.8 21.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_S64 PF08192.11 CDJ56841.1 - 2.9 6.3 10.8 3.4 6.0 10.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3306 PF11748.8 CDJ56841.1 - 3 8.7 16.3 5 8.0 16.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ArAE_2_N PF10337.9 CDJ56841.1 - 3.5 6.6 3.4 4.4 6.2 3.4 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2151 PF10221.9 CDJ56841.1 - 3.9 5.9 17.7 4.7 5.7 17.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Vfa1 PF08432.10 CDJ56841.1 - 4.3 7.6 27.3 6.2 7.1 27.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 CDJ56841.1 - 4.8 6.2 17.5 5.9 5.9 17.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4614 PF15391.6 CDJ56841.1 - 5.5 7.0 11.0 7.3 6.5 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Hid1 PF12722.7 CDJ56841.1 - 5.9 4.9 14.3 6.8 4.7 14.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EOS1 PF12326.8 CDJ56841.1 - 6.6 6.6 5.1 9.2 6.2 5.1 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF2828 PF11443.8 CDJ56841.1 - 6.9 4.6 15.9 8.7 4.3 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PA26 PF04636.13 CDJ56841.1 - 7.8 5.3 11.1 8.7 5.1 11.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ALMT PF11744.8 CDJ56841.1 - 7.9 5.2 11.7 10 4.8 11.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF853 PF05872.12 CDJ56841.1 - 8.1 4.9 6.6 10 4.6 6.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Sec62 PF03839.16 CDJ56841.1 - 8.8 5.8 23.9 12 5.3 23.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 EF-hand_1 PF00036.32 CDJ56842.1 - 4.7e-30 100.9 9.2 2.3e-07 29.9 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ56842.1 - 3.8e-26 89.4 8.3 6.9e-08 31.6 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDJ56842.1 - 2.6e-25 86.1 2.8 7.1e-06 25.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDJ56842.1 - 4.8e-25 87.8 4.1 1.6e-11 44.5 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ56842.1 - 5.5e-11 42.2 9.6 0.0089 15.9 0.2 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CDJ56842.1 - 1.3e-08 34.7 6.1 0.00028 20.8 0.1 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ56842.1 - 6.1e-07 29.8 1.6 0.036 14.4 0.5 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ56842.1 - 0.0074 16.1 1.3 0.12 12.3 0.1 2.9 3 0 0 3 3 3 1 EF hand Caleosin PF05042.13 CDJ56842.1 - 0.037 13.9 0.7 10 6.0 0.0 2.9 1 1 0 2 2 2 0 Caleosin related protein EF-hand_9 PF14658.6 CDJ56842.1 - 0.15 12.4 0.7 4.2 7.8 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain DUF1654 PF07867.11 CDJ56842.1 - 0.16 11.7 0.5 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) CDC45 PF02724.14 CDJ56843.1 - 0.00054 18.4 26.7 0.00054 18.4 26.7 6.2 8 0 0 8 8 8 3 CDC45-like protein Pex14_N PF04695.13 CDJ56844.1 - 0.00038 21.1 21.1 0.00071 20.3 21.1 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ56844.1 - 0.0015 18.6 26.1 0.0016 18.5 26.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ56844.1 - 0.0022 17.7 8.5 0.0022 17.7 8.5 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 CDJ56844.1 - 0.0047 16.5 7.5 0.0049 16.5 7.5 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Bud13 PF09736.9 CDJ56844.1 - 0.01 16.2 7.0 0.013 15.9 7.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PAT1 PF09770.9 CDJ56844.1 - 0.049 11.9 17.1 0.044 12.1 17.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CDJ56844.1 - 0.18 11.9 7.0 0.19 11.8 7.0 1.2 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ56844.1 - 0.25 11.1 7.9 0.29 10.9 7.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 CDJ56844.1 - 0.26 10.5 4.6 0.38 9.9 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase_fungal PF17667.1 CDJ56844.1 - 0.28 9.9 6.0 0.32 9.7 6.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Spt20 PF12090.8 CDJ56844.1 - 0.49 10.0 31.2 0.73 9.4 31.2 1.3 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ56844.1 - 0.6 9.0 30.1 0.82 8.6 30.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Velvet PF11754.8 CDJ56844.1 - 0.63 9.9 14.1 0.86 9.5 14.1 1.3 1 0 0 1 1 1 0 Velvet factor eIF-3_zeta PF05091.12 CDJ56844.1 - 1.2 8.1 14.2 1.4 7.8 14.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CSG2 PF16965.5 CDJ56844.1 - 1.5 7.7 3.3 1.7 7.5 3.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 CDJ56844.1 - 1.6 8.5 5.7 2 8.1 5.7 1.2 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 CDJ56844.1 - 1.6 7.4 9.3 1.9 7.2 9.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GREB1 PF15782.5 CDJ56844.1 - 1.8 5.6 15.3 1.7 5.6 15.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 CDJ56844.1 - 2 8.3 16.4 2.3 8.1 16.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 CDJ56844.1 - 2 6.9 13.5 2.2 6.7 13.5 1.1 1 0 0 1 1 1 0 Macoilin family SpoIIP PF07454.11 CDJ56844.1 - 2.3 7.6 12.3 3.1 7.2 12.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1980 PF09323.10 CDJ56844.1 - 2.6 7.9 7.0 3.6 7.5 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 CDJ56844.1 - 5.3 5.7 19.0 6.3 5.5 19.0 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ56844.1 - 6.2 6.8 12.3 7.9 6.5 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ANAPC4_WD40 PF12894.7 CDJ56845.1 - 2.7e-05 24.4 0.1 0.04 14.2 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ56845.1 - 3.8e-05 24.4 1.9 0.42 11.6 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2722 PF10846.8 CDJ56846.1 - 0.01 14.8 14.6 0.012 14.6 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4770 PF15994.5 CDJ56846.1 - 0.018 15.3 6.8 0.017 15.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sec62 PF03839.16 CDJ56846.1 - 0.03 13.8 4.2 0.03 13.8 4.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3504 PF12012.8 CDJ56846.1 - 0.039 13.9 8.1 0.057 13.3 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) DUF4175 PF13779.6 CDJ56846.1 - 0.041 11.8 7.4 0.037 12.0 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 CDJ56846.1 - 0.046 13.3 18.1 0.052 13.1 18.1 1.1 1 0 0 1 1 1 0 Spt20 family Ctr PF04145.15 CDJ56846.1 - 0.05 14.2 2.8 0.061 13.9 2.8 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PEX11 PF05648.14 CDJ56846.1 - 0.064 12.7 3.6 0.076 12.5 3.6 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF755 PF05501.11 CDJ56846.1 - 0.068 13.5 35.3 0.067 13.5 14.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) OAD_gamma PF04277.13 CDJ56846.1 - 0.072 13.7 0.6 0.098 13.3 0.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Connexin PF00029.19 CDJ56846.1 - 0.084 12.6 4.2 0.1 12.4 4.2 1.2 1 0 0 1 1 1 0 Connexin Gti1_Pac2 PF09729.9 CDJ56846.1 - 0.1 12.7 8.7 0.12 12.4 8.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EIIBC-GUT_N PF03612.14 CDJ56846.1 - 0.19 11.4 5.8 0.25 11.1 5.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 CDJ56846.1 - 0.2 9.6 4.6 0.2 9.5 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3464 PF11947.8 CDJ56846.1 - 0.2 11.4 8.7 0.32 10.7 8.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peroxin-13_N PF04088.13 CDJ56846.1 - 0.29 11.4 2.5 0.42 10.9 2.5 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_S49_N PF08496.10 CDJ56846.1 - 0.32 11.1 11.0 0.4 10.7 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 CDJ56846.1 - 0.32 9.7 9.3 0.35 9.6 9.3 1.0 1 0 0 1 1 1 0 Presenilin DUF2098 PF09871.9 CDJ56846.1 - 0.35 11.2 5.2 0.49 10.8 5.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) FHIPEP PF00771.20 CDJ56846.1 - 0.38 9.1 1.9 0.37 9.2 1.9 1.0 1 0 0 1 1 1 0 FHIPEP family EMC3_TMCO1 PF01956.16 CDJ56846.1 - 0.5 10.1 3.6 0.48 10.1 3.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CLN3 PF02487.17 CDJ56846.1 - 0.58 9.1 2.6 0.5 9.4 2.6 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4457 PF14652.6 CDJ56846.1 - 0.65 9.2 4.7 0.74 9.0 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DNApol_Exo PF18136.1 CDJ56846.1 - 0.69 9.0 7.9 0.73 8.9 7.9 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Folate_carrier PF01770.18 CDJ56846.1 - 0.8 8.4 4.4 0.89 8.2 4.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Paramyxo_ncap PF00973.19 CDJ56846.1 - 1.3 7.8 6.0 1.4 7.8 6.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Band_3_cyto PF07565.13 CDJ56846.1 - 1.7 8.4 6.9 1.9 8.2 6.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ56846.1 - 2.2 7.0 7.4 2.3 7.0 7.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PigN PF04987.14 CDJ56846.1 - 2.5 6.9 3.8 3 6.6 3.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) VKG_Carbox PF05090.14 CDJ56846.1 - 2.7 6.8 3.7 2.9 6.6 3.7 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Zip PF02535.22 CDJ56846.1 - 2.9 7.0 5.6 3.2 6.9 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM51 PF15345.6 CDJ56846.1 - 4.3 7.1 16.4 0.33 10.7 10.9 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 Jak1_Phl PF17887.1 CDJ56846.1 - 4.4 7.3 15.8 3.8 7.5 14.8 1.3 1 1 0 1 1 1 0 Jak1 pleckstrin homology-like domain Conotoxin PF02950.17 CDJ56846.1 - 4.7 8.3 18.1 20 6.3 18.1 2.0 1 1 0 1 1 1 0 Conotoxin DivIC PF04977.15 CDJ56846.1 - 9.3 6.1 14.2 12 5.7 14.2 1.1 1 0 0 1 1 1 0 Septum formation initiator Sporozoite_P67 PF05642.11 CDJ56847.1 - 0.011 13.9 0.0 0.011 13.9 0.0 7.2 4 3 1 5 5 5 0 Sporozoite P67 surface antigen EFTUD2 PF16004.5 CDJ56848.1 - 3e-13 50.4 1.8 3e-13 50.4 1.8 5.3 2 2 2 4 4 4 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Cwf_Cwc_15 PF04889.12 CDJ56848.1 - 0.0027 17.5 8.2 0.0027 17.5 8.2 3.4 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Aim21 PF11489.8 CDJ56848.1 - 0.0032 16.5 9.9 0.0032 16.5 9.9 2.8 2 1 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Nha1_C PF08619.10 CDJ56848.1 - 0.16 11.1 32.0 0.023 13.9 9.2 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Macoilin PF09726.9 CDJ56848.1 - 1.1 7.7 30.1 0.62 8.6 11.5 2.4 2 0 0 2 2 2 0 Macoilin family Apt1 PF10351.9 CDJ56848.1 - 1.4 7.7 30.2 0.22 10.3 10.3 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Utp14 PF04615.13 CDJ56848.1 - 4.6 5.7 37.5 8.7 4.8 37.5 1.3 1 1 0 1 1 1 0 Utp14 protein Peptidase_S64 PF08192.11 CDJ56848.1 - 5.3 5.4 26.9 2.4 6.5 11.3 2.2 2 0 0 2 2 2 0 Peptidase family S64 Aminotran_3 PF00202.21 CDJ56849.1 - 1.3e-83 280.9 0.0 1.5e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDJ56849.1 - 0.0028 16.9 0.0 0.071 12.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II DnaJ PF00226.31 CDJ56850.1 - 8.8e-12 45.0 0.1 2.3e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Stress-antifung PF01657.17 CDJ56850.1 - 0.17 12.5 2.9 1.2 9.8 0.4 3.0 2 0 0 2 2 2 0 Salt stress response/antifungal KH_1 PF00013.29 CDJ56851.1 - 1.1e-42 143.7 0.0 1.3e-11 44.2 0.2 6.2 6 0 0 6 6 6 5 KH domain KH_2 PF07650.17 CDJ56851.1 - 0.034 14.0 0.0 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 KH domain Mem_trans PF03547.18 CDJ56851.1 - 0.4 9.0 2.5 1.1 7.6 2.5 1.7 1 1 0 1 1 1 0 Membrane transport protein MFS_1 PF07690.16 CDJ56852.1 - 8e-09 34.9 37.9 1.3e-05 24.4 14.8 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDJ56852.1 - 0.0045 15.9 1.5 0.041 12.7 0.0 2.4 2 1 0 2 2 2 1 MFS_1 like family Pkinase PF00069.25 CDJ56853.1 - 1.3e-20 73.9 0.0 7.1e-20 71.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ56853.1 - 2.7e-17 63.0 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ56853.1 - 0.0057 16.0 0.0 0.018 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Beta-lactamase PF00144.24 CDJ56854.1 - 4.8e-41 141.1 0.0 8e-36 123.9 0.0 3.2 3 0 0 3 3 3 3 Beta-lactamase CK_II_beta PF01214.18 CDJ56855.1 - 3.5e-63 212.7 0.0 5.4e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Radial_spoke PF04712.12 CDJ56855.1 - 0.36 9.7 7.4 0.46 9.4 7.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 CDJ56855.1 - 3.3 5.7 6.5 3.5 5.6 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi AAA_33 PF13671.6 CDJ56856.1 - 1.2e-27 96.8 0.1 1.2e-27 96.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 CDJ56856.1 - 4.9e-15 55.7 0.0 4.9e-15 55.7 0.0 2.6 2 0 0 2 2 2 1 SPRY domain AAA_18 PF13238.6 CDJ56856.1 - 0.012 16.1 0.1 0.04 14.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain GREB1 PF15782.5 CDJ56856.1 - 3.1 4.8 10.0 4.7 4.2 10.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_M28 PF04389.17 CDJ56857.1 - 5.1e-24 85.1 0.0 1.1e-23 84.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Tom22 PF04281.13 CDJ56857.1 - 0.0072 16.1 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 RLL PF10036.9 CDJ56857.1 - 0.09 12.6 0.7 0.19 11.5 0.7 1.5 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Wza_C PF18412.1 CDJ56857.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain Spt20 PF12090.8 CDJ56857.1 - 0.14 11.8 4.6 0.38 10.3 4.6 1.7 1 0 0 1 1 1 0 Spt20 family Metallophos PF00149.28 CDJ56858.1 - 3.1e-31 109.5 0.1 4.6e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CDJ56858.1 - 4.4e-16 59.0 0.0 1.1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 CDJ56858.1 - 8.9e-15 53.6 2.7 0.00082 19.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ56858.1 - 2.2e-11 43.1 2.5 0.011 15.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ56858.1 - 6.2e-05 23.2 0.4 0.025 14.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ56858.1 - 0.00018 21.4 0.4 0.12 12.7 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ56858.1 - 0.0002 21.0 0.5 0.11 12.2 0.1 2.9 2 1 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 CDJ56858.1 - 0.00039 20.5 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ56858.1 - 0.0012 19.5 0.1 3.9 8.5 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ56858.1 - 0.046 14.4 0.3 7.9 7.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ56858.1 - 0.046 14.1 0.3 0.21 12.0 0.1 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ56858.1 - 0.091 13.3 1.0 49 4.5 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat bPH_4 PF06713.11 CDJ56858.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain Guanylate_cyc PF00211.20 CDJ56860.1 - 3.1e-17 62.8 1.3 5e-17 62.1 0.2 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 CDJ56860.1 - 2e-06 27.2 5.0 2e-06 27.2 5.0 1.9 3 0 0 3 3 3 1 Ion transport protein PSII PF00421.19 CDJ56860.1 - 0.051 12.2 1.1 0.1 11.2 1.1 1.4 1 0 0 1 1 1 0 Photosystem II protein MSC PF09402.10 CDJ56861.1 - 6.2e-13 48.9 2.2 6.9e-13 48.8 1.6 1.4 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain LRR_4 PF12799.7 CDJ56862.1 - 8.5e-16 57.8 14.1 7.9e-06 26.1 0.2 5.3 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ56862.1 - 2.7e-14 52.7 11.4 2.2e-05 24.1 0.1 5.1 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CDJ56862.1 - 4.4e-06 26.3 2.9 0.0012 18.3 0.6 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDJ56862.1 - 2.8e-05 23.8 6.7 0.87 9.8 0.0 6.5 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.33 CDJ56862.1 - 0.1 13.2 12.6 9.1 7.3 0.0 6.5 7 1 0 7 7 7 0 Leucine Rich Repeat Mod_r PF07200.13 CDJ56864.1 - 0.035 14.2 2.2 0.11 12.6 2.2 1.9 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MerR_2 PF13591.6 CDJ56864.1 - 0.14 12.1 0.3 0.37 10.7 0.3 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein TPR_2 PF07719.17 CDJ56865.1 - 0.017 15.2 1.0 0.09 12.9 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ56865.1 - 0.05 14.4 2.0 0.17 12.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NTP_transf_3 PF12804.7 CDJ56867.1 - 3.9e-13 50.1 0.1 1.3e-12 48.3 0.1 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CDJ56867.1 - 3.7e-12 46.4 0.0 6.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDJ56867.1 - 0.00011 21.8 1.0 0.18 11.6 0.1 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CDJ56867.1 - 0.0008 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CDJ56867.1 - 0.0046 15.2 0.1 0.0065 14.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 CDJ56867.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase FAD_syn PF06574.12 CDJ56868.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 FAD synthetase CTP_transf_like PF01467.26 CDJ56868.1 - 0.06 13.5 0.1 0.63 10.2 0.0 2.6 3 1 0 3 3 3 0 Cytidylyltransferase-like Mononeg_RNA_pol PF00946.19 CDJ56869.1 - 0.12 9.9 0.2 0.17 9.5 0.2 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase DUF4229 PF14012.6 CDJ56870.1 - 2.2 8.4 6.8 3.1 7.9 1.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) IMPDH PF00478.25 CDJ56871.1 - 5.7e-127 423.5 4.9 7.5e-127 423.1 4.9 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDJ56871.1 - 1e-11 45.1 0.2 0.00037 20.9 0.0 3.0 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 CDJ56871.1 - 2.5e-10 39.9 2.5 3.1e-10 39.6 1.0 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CDJ56871.1 - 4.8e-10 39.3 6.3 4.7e-06 26.2 6.3 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CDJ56871.1 - 1.1e-05 25.1 2.4 6.5e-05 22.5 2.4 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 CDJ56871.1 - 0.00046 19.4 1.3 0.27 10.4 0.1 2.9 1 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 CDJ56871.1 - 0.0025 17.2 2.6 0.0043 16.4 1.9 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 CDJ56871.1 - 0.024 14.0 1.0 0.11 11.8 0.7 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 CDJ56871.1 - 0.037 13.2 2.0 0.087 11.9 2.0 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 CDJ56871.1 - 0.053 12.7 1.2 0.13 11.4 1.2 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 CDJ56871.1 - 0.071 12.5 0.6 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NAD_binding_7 PF13241.6 CDJ56871.1 - 0.21 12.0 0.8 24 5.4 0.1 2.5 1 1 1 2 2 2 0 Putative NAD(P)-binding Exo_endo_phos PF03372.23 CDJ56872.1 - 2.5e-07 30.5 0.0 1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CDJ56873.1 - 4.8e-33 114.6 0.0 7.4e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56873.1 - 2.1e-23 82.9 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ56873.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltrans_SAM PF10672.9 CDJ56874.1 - 1.1e-08 34.6 0.0 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase MTS PF05175.14 CDJ56874.1 - 6.5e-07 29.0 0.3 0.0042 16.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Cons_hypoth95 PF03602.15 CDJ56874.1 - 4.9e-05 23.0 1.3 0.1 12.3 0.4 2.2 1 1 1 2 2 2 2 Conserved hypothetical protein 95 PUA_3 PF17785.1 CDJ56874.1 - 5.4e-05 22.9 0.0 0.0002 21.1 0.0 1.9 2 0 0 2 2 2 1 PUA-like domain Methyltransf_18 PF12847.7 CDJ56874.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CDJ56874.1 - 0.0032 18.5 0.2 0.021 15.8 0.3 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ56874.1 - 0.0059 17.3 0.3 0.027 15.2 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain N6-adenineMlase PF10237.9 CDJ56874.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_31 PF13847.6 CDJ56874.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CDJ56874.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LRV PF01816.17 CDJ56874.1 - 0.96 10.0 6.6 7.2 7.2 1.9 3.7 2 0 0 2 2 2 0 Leucine rich repeat variant Secretin_N_2 PF07655.13 CDJ56875.1 - 5.1 7.7 28.4 3 8.4 23.4 3.2 2 0 0 2 2 2 0 Secretin N-terminal domain Spt20 PF12090.8 CDJ56876.1 - 0.96 9.0 18.8 1.4 8.5 18.8 1.1 1 0 0 1 1 1 0 Spt20 family Tim54 PF11711.8 CDJ56876.1 - 2.1 7.1 6.8 3 6.5 6.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Roughex PF06020.11 CDJ56876.1 - 7.4 5.6 11.9 12 4.9 11.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein GREB1 PF15782.5 CDJ56876.1 - 9.6 3.2 6.5 11 3.0 6.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer rRNA_proc-arch PF13234.6 CDJ56878.1 - 8.3e-44 150.5 0.5 1.6e-23 84.0 0.0 2.7 2 1 1 3 3 3 2 rRNA-processing arch domain DSHCT PF08148.12 CDJ56878.1 - 4.7e-18 65.4 4.1 2.3e-17 63.1 4.1 2.2 1 1 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDJ56878.1 - 1.2e-15 57.7 0.0 3.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ56878.1 - 1.4e-06 28.6 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IFP_35_N PF07334.13 CDJ56878.1 - 1.7 8.8 6.5 6.6 6.9 1.2 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ras PF00071.22 CDJ56879.1 - 3.9e-66 221.6 0.7 4.6e-66 221.4 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ56879.1 - 1.9e-36 124.9 0.1 3.6e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ56879.1 - 3.4e-18 65.7 0.1 4.5e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDJ56879.1 - 1.6e-05 24.9 0.8 0.13 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CDJ56879.1 - 2.5e-05 23.8 0.1 3.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ56879.1 - 2.7e-05 23.6 0.1 4.8e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDJ56879.1 - 6.4e-05 23.0 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ56879.1 - 0.00012 21.6 0.4 0.00027 20.5 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CDJ56879.1 - 0.0096 15.7 0.1 0.052 13.3 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CDJ56879.1 - 0.026 14.9 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CDJ56879.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 CDJ56879.1 - 0.051 12.9 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 CDJ56879.1 - 0.053 13.1 0.1 0.41 10.1 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 CDJ56879.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ56879.1 - 0.053 13.8 0.0 0.072 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDJ56879.1 - 0.066 12.7 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SpoIIE PF07228.12 CDJ56880.1 - 7.3e-06 26.0 0.0 0.00012 22.1 0.0 2.6 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDJ56880.1 - 0.0001 22.0 0.0 0.00038 20.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CDJ56880.1 - 0.05 13.2 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Gpi1 PF05024.15 CDJ56881.1 - 5.6e-36 124.4 15.8 5.6e-26 91.8 6.0 3.0 3 0 0 3 3 3 2 N-acetylglucosaminyl transferase component (Gpi1) TFIIE-A_C PF11521.8 CDJ56881.1 - 1.2 9.5 5.5 3 8.2 5.5 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha C2 PF00168.30 CDJ56883.1 - 3.7e-06 27.1 0.0 6.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF3446 PF11928.8 CDJ56883.1 - 8.5 6.8 14.9 1.7 9.0 1.6 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain DEAD PF00270.29 CDJ56884.1 - 5.5e-10 39.3 0.0 8e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase TetR_C_36 PF18598.1 CDJ56884.1 - 0.0046 16.9 0.0 0.016 15.2 0.0 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 CDJ56884.1 - 0.11 12.7 0.0 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 CDJ56886.1 - 5.4e-29 100.2 0.1 1e-28 99.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ56886.1 - 1.6e-27 95.8 0.1 4.1e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ56886.1 - 2.6e-13 50.2 0.1 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDJ56886.1 - 0.0049 16.6 3.0 0.006 16.3 0.3 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CDJ56886.1 - 0.0092 15.5 0.0 0.23 10.9 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S4e PF00900.20 CDJ56887.1 - 1.1e-31 108.5 1.7 6.4e-31 106.1 1.2 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CDJ56887.1 - 2.5e-24 84.6 0.3 4.5e-24 83.8 0.3 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 CDJ56887.1 - 3e-06 26.8 0.0 6.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CDJ56887.1 - 3.1e-05 23.8 1.1 0.0001 22.1 1.1 1.8 1 0 0 1 1 1 1 KOW motif Pentapeptide_4 PF13599.6 CDJ56888.1 - 0.028 14.6 1.1 0.046 13.9 1.1 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) SLC12 PF03522.15 CDJ56889.1 - 0.094 11.7 35.9 0.1 11.6 35.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 CDJ56889.1 - 0.28 10.0 25.0 0.33 9.8 25.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Caldesmon PF02029.15 CDJ56889.1 - 0.35 9.6 44.6 0.44 9.3 44.6 1.1 1 0 0 1 1 1 0 Caldesmon Sin_N PF04801.13 CDJ56889.1 - 0.56 9.4 60.4 0.71 9.0 60.4 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Hid1 PF12722.7 CDJ56889.1 - 0.6 8.2 38.8 0.75 7.9 38.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.13 CDJ56889.1 - 1.2 8.7 33.8 1.4 8.6 33.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 CDJ56889.1 - 1.9 6.7 38.7 2.5 6.3 38.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ASC PF00858.24 CDJ56889.1 - 4 6.3 19.2 5.8 5.8 19.2 1.3 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4045 PF13254.6 CDJ56889.1 - 4.1 6.9 35.6 6.1 6.4 35.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GREB1 PF15782.5 CDJ56889.1 - 5.8 3.9 37.3 6.7 3.7 37.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 CDJ56889.1 - 7.1 6.6 37.6 10 6.1 37.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cys_Met_Meta_PP PF01053.20 CDJ56891.1 - 1.4e-114 382.6 0.0 3.4e-64 216.8 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ56891.1 - 2.3e-07 30.5 0.1 7.2e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CDJ56891.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4407 PF14362.6 CDJ56892.1 - 0.3 10.4 25.0 0.15 11.4 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Isochorismatase PF00857.20 CDJ56893.1 - 1.1e-23 84.3 0.1 3.5e-20 72.9 0.1 2.3 2 1 0 2 2 2 2 Isochorismatase family RskA PF10099.9 CDJ56894.1 - 0.0016 18.8 23.9 0.0016 18.8 23.9 3.2 1 1 1 3 3 3 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ56894.1 - 0.44 10.5 36.4 0.55 10.2 36.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.11 CDJ56894.1 - 10 5.7 14.4 3.2 7.4 1.5 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SR-25 PF10500.9 CDJ56895.1 - 0.00025 20.7 15.1 0.00032 20.4 15.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ56895.1 - 0.0005 19.7 23.8 0.00059 19.5 23.8 1.2 1 0 0 1 1 1 1 Spt20 family DDRGK PF09756.9 CDJ56895.1 - 0.0031 17.1 9.1 0.0031 17.1 9.1 1.1 1 0 0 1 1 1 1 DDRGK domain Androgen_recep PF02166.16 CDJ56895.1 - 0.0079 15.1 13.2 0.0087 14.9 13.2 1.0 1 0 0 1 1 1 1 Androgen receptor PI3K_1B_p101 PF10486.9 CDJ56895.1 - 0.031 12.1 13.2 0.033 12.0 13.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2722 PF10846.8 CDJ56895.1 - 0.039 12.9 20.1 0.055 12.4 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ESM4 PF15952.5 CDJ56895.1 - 0.04 14.4 16.0 0.047 14.1 16.0 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family RPN2_C PF18004.1 CDJ56895.1 - 0.053 13.4 12.5 0.06 13.3 12.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFIIF_alpha PF05793.12 CDJ56895.1 - 0.065 11.8 14.6 0.078 11.6 14.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tim54 PF11711.8 CDJ56895.1 - 0.066 12.0 8.0 0.075 11.8 8.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 CDJ56895.1 - 0.069 13.3 15.0 0.075 13.2 15.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MPM1 PF17234.2 CDJ56895.1 - 0.072 13.3 13.3 0.084 13.1 13.3 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Macoilin PF09726.9 CDJ56895.1 - 0.073 11.6 18.6 0.076 11.6 18.6 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 CDJ56895.1 - 0.074 11.5 15.4 0.079 11.4 15.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 MDM1 PF15501.6 CDJ56895.1 - 0.075 12.2 15.5 0.088 12.0 15.5 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 CSRNP_N PF16019.5 CDJ56895.1 - 0.075 12.9 10.5 0.084 12.8 10.5 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tub_N PF16322.5 CDJ56895.1 - 0.078 13.4 20.5 0.1 13.0 20.5 1.1 1 0 0 1 1 1 0 Tubby N-terminal TFIIA PF03153.13 CDJ56895.1 - 0.088 12.8 22.5 0.09 12.8 22.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4718 PF15842.5 CDJ56895.1 - 0.11 12.3 9.5 0.12 12.1 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) FAM176 PF14851.6 CDJ56895.1 - 0.12 12.1 11.9 0.14 11.8 11.9 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CDJ56895.1 - 0.12 10.4 11.9 0.13 10.3 11.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Plasmodium_Vir PF05795.11 CDJ56895.1 - 0.16 11.3 14.4 0.2 11.1 14.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CNDH2_C PF16858.5 CDJ56895.1 - 0.16 11.8 13.6 0.17 11.8 13.6 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Sporozoite_P67 PF05642.11 CDJ56895.1 - 0.16 10.0 18.2 0.2 9.7 18.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3_zeta PF05091.12 CDJ56895.1 - 0.19 10.7 13.1 0.22 10.5 13.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RPOL_N PF14700.6 CDJ56895.1 - 0.19 11.1 11.0 0.22 10.9 11.0 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF702 PF05142.12 CDJ56895.1 - 0.21 12.0 8.5 0.3 11.6 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Med15 PF09606.10 CDJ56895.1 - 0.22 10.2 17.9 0.22 10.2 17.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF853 PF05872.12 CDJ56895.1 - 0.22 10.1 7.6 0.25 9.9 7.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cwf_Cwc_15 PF04889.12 CDJ56895.1 - 0.24 11.1 13.7 0.29 10.9 13.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NST1 PF13945.6 CDJ56895.1 - 0.26 11.3 21.4 0.32 11.1 21.4 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Pox_Ag35 PF03286.14 CDJ56895.1 - 0.27 11.0 12.7 0.33 10.7 12.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4770 PF15994.5 CDJ56895.1 - 0.35 11.1 9.8 0.39 10.9 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Myc_N PF01056.18 CDJ56895.1 - 0.35 10.7 13.4 0.44 10.4 13.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Lin-8 PF03353.15 CDJ56895.1 - 0.37 10.3 21.3 0.45 10.0 21.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 CDJ56895.1 - 0.4 9.6 9.8 0.45 9.4 9.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4647 PF15504.6 CDJ56895.1 - 0.45 9.6 12.5 0.47 9.5 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) TRAP_alpha PF03896.16 CDJ56895.1 - 0.8 8.9 7.3 0.77 8.9 7.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3381 PF11861.8 CDJ56895.1 - 0.86 9.4 13.4 0.93 9.3 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Miga PF10265.9 CDJ56895.1 - 0.9 8.4 12.7 0.97 8.3 12.7 1.0 1 0 0 1 1 1 0 Mitoguardin Mem_trans PF03547.18 CDJ56895.1 - 1 7.7 13.8 1.1 7.6 13.8 1.0 1 0 0 1 1 1 0 Membrane transport protein Nop53 PF07767.11 CDJ56895.1 - 1.1 8.6 15.7 1.2 8.4 15.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MscS_TM PF12794.7 CDJ56895.1 - 1.1 8.1 7.1 1.1 8.1 7.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Selenoprotein_S PF06936.11 CDJ56895.1 - 1.1 9.0 12.9 1.4 8.7 12.9 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) RR_TM4-6 PF06459.12 CDJ56895.1 - 1.1 9.0 15.0 1.3 8.7 15.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CDJ56895.1 - 1.3 6.0 16.7 1.4 6.0 16.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 CDJ56895.1 - 1.4 7.5 12.4 1.6 7.3 12.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mif2_N PF15624.6 CDJ56895.1 - 1.6 9.5 12.2 2 9.1 12.2 1.1 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SLC12 PF03522.15 CDJ56895.1 - 1.6 7.7 15.7 1.8 7.5 15.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PBP1_TM PF14812.6 CDJ56895.1 - 1.8 9.0 7.7 2.5 8.5 7.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4692 PF15763.5 CDJ56895.1 - 1.9 9.0 11.6 2.4 8.6 11.6 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Menin PF05053.13 CDJ56895.1 - 2.1 6.6 12.5 2.3 6.5 12.5 1.1 1 0 0 1 1 1 0 Menin PTPRCAP PF15713.5 CDJ56895.1 - 2.3 8.5 16.8 2.8 8.2 16.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Pet20 PF08692.10 CDJ56895.1 - 2.4 8.9 7.6 3 8.6 7.6 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Connexin PF00029.19 CDJ56895.1 - 2.5 7.8 8.9 2.7 7.7 8.9 1.2 1 0 0 1 1 1 0 Connexin Paramyxo_ncap PF00973.19 CDJ56895.1 - 2.6 6.8 12.8 3.1 6.6 12.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Med24_N PF11277.8 CDJ56895.1 - 2.8 5.9 13.1 3.2 5.7 13.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF4746 PF15928.5 CDJ56895.1 - 2.9 7.2 12.7 3.4 7.0 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 CDJ56895.1 - 3.2 6.0 14.3 3.7 5.7 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein PNISR PF15996.5 CDJ56895.1 - 3.2 8.0 19.4 4.1 7.6 19.4 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4175 PF13779.6 CDJ56895.1 - 3.4 5.4 16.7 3.1 5.6 16.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gti1_Pac2 PF09729.9 CDJ56895.1 - 3.5 7.7 14.0 4.4 7.4 14.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4611 PF15387.6 CDJ56895.1 - 3.8 7.8 14.1 3.5 7.9 13.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) BORG_CEP PF14957.6 CDJ56895.1 - 4.3 8.5 16.0 5.4 8.2 16.0 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF2151 PF10221.9 CDJ56895.1 - 4.3 5.8 12.7 5.2 5.5 12.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4820 PF16091.5 CDJ56895.1 - 4.6 6.5 19.2 3.3 7.0 17.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4199 PF13858.6 CDJ56895.1 - 4.7 7.6 6.3 5.4 7.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CPSF100_C PF13299.6 CDJ56895.1 - 4.9 7.3 12.2 7.8 6.6 12.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDP_N PF12278.8 CDJ56895.1 - 5 7.3 16.7 6.7 6.8 16.7 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Presenilin PF01080.17 CDJ56895.1 - 5.5 5.6 19.8 6.4 5.4 19.8 1.0 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ56895.1 - 6.3 5.5 17.6 6.9 5.4 17.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 CDJ56895.1 - 6.5 6.7 11.4 6.8 6.7 11.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ56895.1 - 6.5 5.7 11.6 6.9 5.6 11.6 1.1 1 0 0 1 1 1 0 CLN3 protein Cellulose_synt PF03552.14 CDJ56895.1 - 7 5.0 6.9 7.5 4.9 6.9 1.0 1 0 0 1 1 1 0 Cellulose synthase MCM_bind PF09739.9 CDJ56895.1 - 7.1 5.0 17.4 8.3 4.7 17.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF1645 PF07816.11 CDJ56895.1 - 7.3 7.1 15.3 9.3 6.8 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Folliculin PF11704.8 CDJ56895.1 - 7.8 6.3 12.1 11 5.9 12.1 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Membralin PF09746.9 CDJ56895.1 - 8.1 5.4 10.8 7.9 5.4 10.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein XRN_M PF17846.1 CDJ56895.1 - 8.4 5.2 11.1 8.3 5.2 11.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Strabismus PF06638.11 CDJ56895.1 - 8.6 4.9 9.8 9.7 4.7 9.8 1.0 1 0 0 1 1 1 0 Strabismus protein PPL5 PF18168.1 CDJ56895.1 - 8.7 5.5 10.4 9.9 5.4 10.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CobT PF06213.12 CDJ56895.1 - 8.7 5.6 20.9 11 5.3 20.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.13 CDJ56895.1 - 9 6.0 14.0 11 5.7 14.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sec62 PF03839.16 CDJ56895.1 - 9.5 5.7 8.9 11 5.4 8.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ribosomal_60s PF00428.19 CDJ56897.1 - 0.017 15.7 10.7 0.017 15.7 10.7 20.8 4 2 12 16 16 16 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ56897.1 - 0.72 10.1 26.2 0.74 10.1 2.8 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA ARL17 PF15840.5 CDJ56898.1 - 0.12 12.7 6.2 1.4 9.4 1.2 3.8 3 0 0 3 3 3 0 ADP-ribosylation factor-like protein 17 EBP50_C PF09007.11 CDJ56899.1 - 0.32 12.0 0.1 0.32 12.0 0.1 2.8 2 1 1 3 3 3 0 EBP50, C-terminal PACT_coil_coil PF10495.9 CDJ56899.1 - 0.65 10.6 4.5 1.3 9.6 4.5 1.4 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF2722 PF10846.8 CDJ56899.1 - 5 6.0 19.9 0.16 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) HEAT PF02985.22 CDJ56900.1 - 6.5e-14 50.8 10.5 0.0039 17.3 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CDJ56900.1 - 6.7e-07 29.6 0.6 6.7e-07 29.6 0.6 6.9 6 1 0 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CDJ56900.1 - 0.0012 18.9 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ56900.1 - 0.018 15.5 0.3 0.018 15.5 0.3 11.1 12 1 1 13 13 13 0 HEAT-like repeat Mem_trans PF03547.18 CDJ56900.1 - 0.21 10.0 8.0 0.22 9.9 0.1 3.9 4 0 0 4 4 4 0 Membrane transport protein PPIP5K2_N PF18086.1 CDJ56901.1 - 2.7e-10 40.3 0.1 3.6e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Macoilin PF09726.9 CDJ56901.1 - 0.22 10.0 10.1 0.29 9.7 10.1 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ56901.1 - 1 8.2 8.4 1.2 7.9 8.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ56901.1 - 6.9 6.5 14.2 8.8 6.1 14.2 1.2 1 0 0 1 1 1 0 SPX domain AAA_25 PF13481.6 CDJ56902.1 - 1.3e-09 37.9 0.0 3.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 CDJ56902.1 - 1.2e-07 32.1 0.1 9.5e-07 29.2 0.0 2.8 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.6 CDJ56902.1 - 0.00013 22.4 0.0 0.00042 20.7 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 CDJ56902.1 - 0.089 13.0 0.0 0.37 11.0 0.0 2.1 1 1 0 1 1 1 0 Toprim domain ATPase PF06745.13 CDJ56902.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Spt20 PF12090.8 CDJ56903.1 - 0.0035 17.0 29.7 0.0035 17.0 29.7 4.0 2 1 0 2 2 2 1 Spt20 family Baculo_PP31 PF05311.11 CDJ56903.1 - 0.077 12.5 21.3 0.1 12.0 4.1 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF2828 PF11443.8 CDJ56903.1 - 0.17 9.9 28.2 0.019 13.1 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ56903.1 - 0.28 11.2 21.3 0.18 11.9 6.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF908 PF06012.12 CDJ56903.1 - 7.1 5.9 18.8 0.46 9.8 5.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Peptidase_M16_M PF16187.5 CDJ56905.1 - 1.4e-25 90.1 18.3 1.8e-23 83.2 15.5 3.0 2 1 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDJ56905.1 - 4.2e-20 72.2 0.0 4.2e-20 72.2 0.0 4.0 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Utp14 PF04615.13 CDJ56905.1 - 0.003 16.2 0.0 0.003 16.2 0.0 2.1 1 1 0 2 2 2 1 Utp14 protein SPX PF03105.19 CDJ56905.1 - 5.7 6.8 38.5 3.2e+02 1.0 38.5 2.5 1 1 0 1 1 1 0 SPX domain K_channel_TID PF07941.11 CDJ56907.1 - 0.0054 17.2 4.0 0.0054 17.2 4.0 13.2 11 3 2 13 13 13 2 Potassium channel Kv1.4 tandem inactivation domain Glycos_transf_2 PF00535.26 CDJ56908.1 - 6.3e-25 87.9 0.0 1.5e-24 86.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDJ56908.1 - 7.2e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDJ56908.1 - 2.4e-07 30.3 0.5 2.7e-06 26.9 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CDJ56908.1 - 0.00074 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DnaJ PF00226.31 CDJ56909.1 - 1.4e-07 31.5 0.0 6.8e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain Pkinase PF00069.25 CDJ56910.1 - 4.9e-56 190.0 1.1 4e-48 164.1 0.6 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ56910.1 - 4.5e-26 91.7 0.6 7.5e-25 87.7 0.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase McyA_C PF12593.8 CDJ56910.1 - 0.00058 19.6 1.7 0.082 12.7 1.6 2.7 2 0 0 2 2 2 1 Microcystin synthetase C terminal APH PF01636.23 CDJ56910.1 - 0.013 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ56910.1 - 0.03 13.3 0.2 0.076 11.9 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CDJ56910.1 - 0.043 12.6 0.4 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CDJ56910.1 - 0.14 11.5 0.3 0.29 10.4 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 CDJ56911.1 - 0.0011 19.6 0.0 0.0017 18.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fasciclin PF02469.22 CDJ56912.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain UCH PF00443.29 CDJ56913.1 - 8.4e-36 123.8 0.0 1.1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ56913.1 - 8.5e-06 25.6 0.4 0.036 13.7 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDJ56913.1 - 3.9e-05 23.3 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ56913.1 - 0.084 13.3 0.1 3.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ56913.1 - 0.089 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Med3 PF11593.8 CDJ56913.1 - 0.35 10.0 2.7 0.65 9.1 2.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mfa1 PF17445.2 CDJ56914.1 - 0.06 13.4 3.1 0.28 11.3 1.3 2.8 2 0 0 2 2 2 0 Mating factor A1 DUF615 PF04751.14 CDJ56915.1 - 0.0011 19.0 2.5 0.0016 18.4 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) HetR_C PF18460.1 CDJ56915.1 - 0.0097 15.8 1.2 0.019 14.9 1.2 1.5 1 0 0 1 1 1 1 Heterocyst differentiation regulator C-terminal Hood domain Herpes_UL7 PF01677.16 CDJ56915.1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like Zwilch PF09817.9 CDJ56915.1 - 0.084 11.3 1.8 0.13 10.7 1.8 1.2 1 0 0 1 1 1 0 RZZ complex, subunit zwilch Sporozoite_P67 PF05642.11 CDJ56919.1 - 0.64 8.0 14.5 0.78 7.8 14.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MORN PF02493.20 CDJ56920.1 - 7.2e-40 132.5 57.5 3.2e-07 29.8 1.5 8.7 8 1 1 9 9 9 8 MORN repeat Spt20 PF12090.8 CDJ56920.1 - 0.16 11.5 26.0 0.26 10.9 26.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF853 PF05872.12 CDJ56920.1 - 0.47 9.0 9.0 0.67 8.5 9.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.12 CDJ56920.1 - 0.52 9.2 12.6 0.7 8.8 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 CDJ56920.1 - 0.54 9.0 8.5 0.73 8.6 8.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4677 PF15726.5 CDJ56920.1 - 1.8 8.7 5.6 4.5 7.4 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4677) Pal1 PF08316.11 CDJ56920.1 - 3.1 8.6 9.5 3.1 8.5 7.9 1.8 1 1 0 1 1 1 0 Pal1 cell morphology protein CDC45 PF02724.14 CDJ56920.1 - 3.4 5.8 12.5 5.1 5.3 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CDJ56920.1 - 5.6 5.7 12.1 6.8 5.4 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AC_N PF16214.5 CDJ56920.1 - 6.6 5.8 12.3 9 5.3 12.3 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PAT1 PF09770.9 CDJ56920.1 - 8.4 4.5 18.4 11 4.2 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2545 PF10810.8 CDJ56921.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) ADH_zinc_N PF00107.26 CDJ56922.1 - 3.9e-10 39.8 0.0 6.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDJ56922.1 - 0.00013 23.0 0.0 0.00019 22.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_C97 PF05903.14 CDJ56923.1 - 1.3e-22 80.3 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Secretin_N_2 PF07655.13 CDJ56923.1 - 0.63 10.6 48.0 0.057 14.0 6.8 3.7 3 0 0 3 3 3 0 Secretin N-terminal domain LRAT PF04970.13 CDJ56923.1 - 2 8.7 3.8 5.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Lecithin retinol acyltransferase Spt20 PF12090.8 CDJ56923.1 - 4.2 6.9 26.1 1 8.9 10.8 3.3 3 0 0 3 3 3 0 Spt20 family cwf18 PF08315.12 CDJ56923.1 - 5.1 7.8 12.3 4.4 8.0 2.6 2.8 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor Ribosomal_L23 PF00276.20 CDJ56925.1 - 6.5e-08 32.8 0.0 9.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 SinI PF08671.10 CDJ56925.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Anti-repressor SinI Arm PF00514.23 CDJ56926.1 - 3.6e-74 242.8 18.9 4.4e-14 51.9 0.0 7.1 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDJ56926.1 - 7.8e-23 80.6 8.0 3.2e-07 30.7 0.1 6.3 4 3 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 CDJ56926.1 - 4.9e-19 68.5 2.6 1.8e-06 28.3 0.1 4.4 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.22 CDJ56926.1 - 8.3e-11 41.2 8.7 0.0081 16.3 0.0 7.1 7 1 0 7 7 7 3 HEAT repeat V-ATPase_H_C PF11698.8 CDJ56926.1 - 4.2e-05 23.6 0.0 0.048 13.8 0.0 3.2 2 1 2 4 4 4 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 CDJ56926.1 - 0.00058 19.8 0.0 0.13 12.3 0.0 2.9 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 CDJ56926.1 - 0.00062 20.0 1.9 0.22 11.8 0.0 4.2 5 2 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 CDJ56926.1 - 0.00064 19.2 0.0 0.071 12.6 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like HEAT_PBS PF03130.16 CDJ56926.1 - 0.022 15.4 9.9 0.45 11.3 0.1 5.6 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 CDJ56926.1 - 0.038 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Dehydrin PF00257.19 CDJ56927.1 - 1.3 9.5 7.9 0.62 10.6 1.5 2.3 2 0 0 2 2 2 0 Dehydrin TFIIA PF03153.13 CDJ56927.1 - 3.8 7.4 25.8 5.2 7.0 25.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.12 CDJ56927.1 - 9.2 5.1 7.3 12 4.8 7.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GTP_EFTU PF00009.27 CDJ56928.1 - 3.4e-20 72.4 0.6 1e-15 57.8 0.1 2.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 CDJ56928.1 - 4.7e-10 39.7 0.0 1.6e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDJ56928.1 - 3e-08 33.8 3.2 7.2e-07 29.3 1.4 2.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CDJ56928.1 - 8.6e-07 28.7 0.0 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Ras family Arf PF00025.21 CDJ56928.1 - 1.5e-06 27.8 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CDJ56928.1 - 4.1e-05 23.1 1.7 0.25 10.7 0.0 2.8 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CDJ56928.1 - 0.00032 20.8 1.0 0.00032 20.8 1.0 2.1 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 CDJ56928.1 - 0.00054 19.6 0.2 0.021 14.4 0.3 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RskA PF10099.9 CDJ56928.1 - 0.0018 18.6 2.9 0.0018 18.6 2.9 3.3 2 1 1 3 3 3 2 Anti-sigma-K factor rskA MAP65_ASE1 PF03999.12 CDJ56928.1 - 0.0083 14.9 9.9 0.015 14.0 9.9 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MAM33 PF02330.16 CDJ56928.1 - 0.028 14.4 1.8 5.4 6.9 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein TniB PF05621.11 CDJ56928.1 - 0.039 13.4 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein DUF243 PF03103.17 CDJ56928.1 - 0.041 14.2 7.1 0.71 10.2 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF243) CBP_BcsQ PF06564.12 CDJ56928.1 - 0.044 13.3 2.0 0.073 12.5 0.1 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Thioredoxin_7 PF13899.6 CDJ56928.1 - 0.055 13.6 0.8 14 6.0 0.1 3.1 3 0 0 3 3 3 0 Thioredoxin-like FeoB_N PF02421.18 CDJ56928.1 - 0.062 12.8 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.14 CDJ56928.1 - 0.11 12.3 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CDJ56928.1 - 0.13 12.6 2.3 1.7 9.1 0.2 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3_C PF01915.22 CDJ56928.1 - 1.2 9.1 12.1 0.43 10.5 9.4 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain G-alpha PF00503.20 CDJ56928.1 - 1.6 7.8 12.6 32 3.5 12.7 2.0 1 1 0 1 1 1 0 G-protein alpha subunit TFIIA PF03153.13 CDJ56928.1 - 2.2 8.2 32.7 0.72 9.8 19.1 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CDJ56928.1 - 8.2 5.5 11.6 4.6 6.4 3.4 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter Rpp20 PF12328.8 CDJ56928.1 - 9.5 6.2 10.0 2 8.4 0.4 3.7 3 1 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P DUF4770 PF15994.5 CDJ56928.1 - 9.9 6.4 11.2 1.4 9.2 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4770) RdRP PF05183.12 CDJ56929.1 - 2.3e-16 59.6 2.3 3.5e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 RNA dependent RNA polymerase RskA PF10099.9 CDJ56929.1 - 0.0027 18.0 12.0 0.0027 18.0 12.0 6.6 1 1 3 4 4 4 1 Anti-sigma-K factor rskA PPP4R2 PF09184.11 CDJ56929.1 - 0.15 11.6 12.4 0.19 11.3 8.1 2.3 2 0 0 2 2 2 0 PPP4R2 SF1-HH PF16275.5 CDJ56930.1 - 0.0055 17.0 1.8 0.0055 17.0 1.8 2.3 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain Suf PF05843.14 CDJ56930.1 - 0.029 14.4 7.6 0.015 15.3 2.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ56930.1 - 0.048 14.6 1.6 0.048 14.6 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MNE1 PF13762.6 CDJ56930.1 - 0.061 13.3 1.6 0.077 13.0 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Coilin_N PF15862.5 CDJ56930.1 - 0.28 11.0 14.6 0.34 10.7 2.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus DNA_pol3_a_NII PF11490.8 CDJ56930.1 - 0.34 10.8 15.9 0.031 14.2 2.6 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II MMR1 PF08505.10 CDJ56930.1 - 0.82 9.9 18.0 0.19 12.0 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CDJ56930.1 - 1.1 9.1 27.3 2.7 7.9 27.3 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ56930.1 - 2.5 8.7 17.0 5 7.8 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CDJ56930.1 - 3 7.8 13.7 0.58 10.2 5.3 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Orf78 PF06024.12 CDJ56930.1 - 4.6 7.6 9.6 0.26 11.6 2.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Sporozoite_P67 PF05642.11 CDJ56931.1 - 6.3e-05 21.3 5.9 7.4e-05 21.0 5.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 CDJ56931.1 - 0.00011 22.0 30.3 0.00014 21.7 30.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 CDJ56931.1 - 0.00054 18.3 27.2 0.00062 18.1 27.2 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CDJ56931.1 - 0.0014 18.1 23.2 0.0017 17.8 23.2 1.1 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 CDJ56931.1 - 0.004 16.0 16.4 0.0047 15.8 16.4 1.1 1 0 0 1 1 1 1 Presenilin Caldesmon PF02029.15 CDJ56931.1 - 0.006 15.4 21.1 0.0066 15.3 21.1 1.1 1 0 0 1 1 1 1 Caldesmon MCM_bind PF09739.9 CDJ56931.1 - 0.016 13.7 12.8 0.018 13.5 12.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 CDJ56931.1 - 0.017 13.4 25.4 0.021 13.2 25.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Dynactin_p62 PF05502.13 CDJ56931.1 - 0.044 12.5 12.1 0.054 12.3 12.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family BUD22 PF09073.10 CDJ56931.1 - 0.064 12.6 22.0 0.079 12.3 22.0 1.1 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 CDJ56931.1 - 0.11 12.7 18.9 0.13 12.4 18.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ56931.1 - 0.14 12.0 27.2 0.17 11.7 27.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 CDJ56931.1 - 0.18 12.0 33.3 0.24 11.5 33.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.12 CDJ56931.1 - 0.25 9.7 35.5 0.28 9.6 35.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 CDJ56931.1 - 0.36 9.8 11.7 0.55 9.1 11.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 CDJ56931.1 - 0.44 10.6 11.0 0.61 10.1 11.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FRQ PF09421.10 CDJ56931.1 - 0.56 8.2 12.4 0.59 8.1 12.4 1.1 1 0 0 1 1 1 0 Frequency clock protein Nop53 PF07767.11 CDJ56931.1 - 1 8.7 34.8 1.3 8.3 34.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CLN3 PF02487.17 CDJ56931.1 - 1 8.4 11.7 1.9 7.5 11.7 1.4 1 0 0 1 1 1 0 CLN3 protein Merozoite_SPAM PF07133.11 CDJ56931.1 - 1.4 8.9 43.3 1.9 8.5 43.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Drc1-Sld2 PF11719.8 CDJ56931.1 - 1.4 8.4 21.9 1.8 8.0 21.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4050 PF13259.6 CDJ56931.1 - 1.6 9.0 12.8 2.3 8.5 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PA26 PF04636.13 CDJ56931.1 - 1.7 7.5 16.1 2.1 7.2 16.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PCM1_C PF15717.5 CDJ56931.1 - 1.8 7.2 26.5 2.3 6.8 26.5 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PDDEXK_6 PF04720.12 CDJ56931.1 - 1.8 8.5 14.1 2.5 8.0 14.1 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF4045 PF13254.6 CDJ56931.1 - 2 8.0 16.6 2.3 7.8 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DNA_pol_phi PF04931.13 CDJ56931.1 - 2.4 6.2 37.5 3.2 5.8 37.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAT1 PF09770.9 CDJ56931.1 - 2.5 6.3 21.7 2.7 6.1 21.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IER PF05760.12 CDJ56931.1 - 3 8.1 16.2 3.6 7.8 16.2 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) SLC12 PF03522.15 CDJ56931.1 - 3.1 6.7 19.7 3.5 6.5 19.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 CDJ56931.1 - 3.6 7.9 28.0 4.5 7.6 28.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ALMT PF11744.8 CDJ56931.1 - 3.7 6.3 13.2 4.7 5.9 13.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC27 PF09507.10 CDJ56931.1 - 4.3 6.6 31.2 5.9 6.2 31.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Smg8_Smg9 PF10220.9 CDJ56931.1 - 4.6 5.4 20.3 5.1 5.3 20.3 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Endostatin PF06482.11 CDJ56931.1 - 5.3 6.4 12.8 6.5 6.1 12.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cellulose_synt PF03552.14 CDJ56931.1 - 5.5 5.3 5.0 5.8 5.3 5.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Raftlin PF15250.6 CDJ56931.1 - 6.3 5.4 16.4 7.4 5.2 16.4 1.0 1 0 0 1 1 1 0 Raftlin CNDH2_C PF16858.5 CDJ56931.1 - 8.3 6.2 28.2 11 5.8 28.2 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Suf PF05843.14 CDJ56931.1 - 9.5 6.1 17.9 13 5.7 17.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 CDJ56932.1 - 2.3e-05 23.5 22.8 0.00027 20.0 4.4 6.2 5 1 1 6 6 6 3 Protein of unknown function (DUF2722) Adaptin_binding PF10199.9 CDJ56932.1 - 2.9e-05 24.6 44.6 0.0012 19.4 1.9 5.6 5 1 0 5 5 5 4 Alpha and gamma adaptin binding protein p34 Spt20 PF12090.8 CDJ56932.1 - 0.00014 21.6 12.2 0.00014 21.6 12.2 6.7 7 0 0 7 7 7 3 Spt20 family Connexin PF00029.19 CDJ56932.1 - 0.0018 18.1 0.5 0.0018 18.1 0.5 5.6 4 1 0 5 5 5 3 Connexin Pex14_N PF04695.13 CDJ56932.1 - 0.0081 16.8 11.4 0.0081 16.8 11.4 7.1 5 2 1 6 6 6 3 Peroxisomal membrane anchor protein (Pex14p) conserved region THOC2_N PF16134.5 CDJ56932.1 - 1.7 7.2 45.7 0.053 12.2 9.8 4.5 5 0 0 5 5 5 0 THO complex subunit 2 N-terminus CENP-B_dimeris PF09026.10 CDJ56932.1 - 2.5 8.5 15.1 11 6.5 0.1 4.3 4 0 0 4 4 4 0 Centromere protein B dimerisation domain TCP PF03634.13 CDJ56932.1 - 6.3 7.4 63.6 0.064 13.8 6.7 5.8 5 1 0 5 5 5 0 TCP family transcription factor Metallophos PF00149.28 CDJ56933.1 - 1.4e-16 61.7 0.2 1.9e-07 31.8 0.0 2.6 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PCNA_N PF00705.18 CDJ56935.1 - 1.1e-44 151.1 6.0 5.1e-44 149.0 3.4 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDJ56935.1 - 3.1e-29 101.8 0.0 2.6e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CDJ56935.1 - 6.1e-07 29.2 0.9 0.00044 19.8 0.1 2.1 1 1 0 2 2 2 2 Rad9 PRIMA1 PF16101.5 CDJ56938.1 - 1 9.4 13.2 4.4 7.4 13.2 2.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 tRNA-synt_1d PF00750.19 CDJ56939.1 - 1e-25 90.4 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (R) Ferlin_C PF16165.5 CDJ56941.1 - 0.026 14.5 0.6 0.026 14.5 0.6 4.9 3 1 1 5 5 5 0 Ferlin C-terminus Kelch_4 PF13418.6 CDJ56942.1 - 1.5e-07 31.3 4.7 0.0017 18.3 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ56942.1 - 0.00052 19.5 12.4 0.19 11.4 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 CDJ56942.1 - 0.0018 18.2 5.1 1.3 9.1 0.0 5.0 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CDJ56942.1 - 0.27 11.3 18.5 12 6.0 0.1 6.5 5 1 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 CDJ56942.1 - 0.42 11.0 10.3 57 4.2 0.0 5.1 6 0 0 6 6 6 0 Kelch motif YL1 PF05764.13 CDJ56943.1 - 3.1e-13 50.4 37.3 3.1e-13 50.4 37.3 5.1 3 2 0 4 4 4 1 YL1 nuclear protein AMP-binding PF00501.28 CDJ56943.1 - 6e-05 21.8 3.3 6e-05 21.8 3.3 3.0 3 1 0 3 3 3 1 AMP-binding enzyme DUF1509 PF07420.11 CDJ56943.1 - 2.6 6.9 10.4 4.8 6.1 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SPX PF03105.19 CDJ56944.1 - 0.0026 17.7 4.3 0.0026 17.7 4.3 2.1 2 0 0 2 2 2 1 SPX domain FAM60A PF15396.6 CDJ56944.1 - 0.34 10.9 14.9 0.93 9.5 2.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Herpes_pp85 PF04637.12 CDJ56944.1 - 0.6 8.5 8.3 0.88 7.9 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tme5_EGF_like PF09064.10 CDJ56944.1 - 2.5 8.1 6.1 0.19 11.6 0.5 2.1 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like DUF3740 PF12548.8 CDJ56944.1 - 4.2 7.8 20.2 1.7 9.1 1.6 2.4 2 0 0 2 2 2 0 Sulfatase protein CK_II_beta PF01214.18 CDJ56945.1 - 1.1e-08 35.2 0.2 1.2e-08 34.9 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit TFIIA PF03153.13 CDJ56946.1 - 1.1 9.1 14.3 1.5 8.7 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CDJ56946.1 - 3.1 7.1 8.1 2.7 7.3 0.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SR-25 PF10500.9 CDJ56946.1 - 9.3 5.8 27.6 5.1 6.6 20.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ56947.1 - 0.00065 18.8 13.7 0.00065 18.8 13.7 7.7 7 1 1 8 8 8 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ56947.1 - 0.0011 19.3 5.8 0.0011 19.3 5.8 11.4 4 3 5 9 9 9 2 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ56947.1 - 0.0078 14.4 0.0 0.0078 14.4 0.0 8.1 4 3 1 5 5 5 1 Sporozoite P67 surface antigen PIH1 PF08190.12 CDJ56949.1 - 2.5e-12 46.6 0.0 4.8e-09 35.9 0.0 2.4 1 1 1 2 2 2 2 PIH1 N-terminal domain Methyltransf_15 PF09445.10 CDJ56950.1 - 4.6e-31 107.6 0.0 7.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CDJ56950.1 - 0.00024 20.8 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDJ56950.1 - 0.0024 18.5 0.0 0.0072 17.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ56950.1 - 0.074 13.7 0.1 1.2 9.8 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain HSP90 PF00183.18 CDJ56951.1 - 5e-103 345.7 0.0 3.2e-102 343.1 0.0 1.8 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 CDJ56951.1 - 2.3e-10 40.4 0.0 4.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ56951.1 - 2e-09 38.0 0.0 3.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2183 PF09949.9 CDJ56951.1 - 0.045 14.1 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) HA2 PF04408.23 CDJ56952.1 - 2.2e-09 37.5 0.0 2.2e-09 37.5 0.0 3.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ56952.1 - 2.5e-09 37.5 2.6 1e-08 35.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDJ56952.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold FAM104 PF15434.6 CDJ56952.1 - 0.06 13.9 0.0 0.06 13.9 0.0 4.1 4 0 0 4 4 4 0 Family 104 AP2 PF00847.20 CDJ56954.1 - 4.4e-06 26.8 0.9 4.4e-06 26.8 0.9 4.0 5 0 0 5 5 5 1 AP2 domain Peptidase_S8 PF00082.22 CDJ56955.1 - 1.9e-17 63.5 2.5 1.6e-10 40.7 0.6 4.6 5 1 0 5 5 5 2 Subtilase family RskA PF10099.9 CDJ56955.1 - 1.3e-11 45.1 0.2 8.9e-06 26.1 2.5 15.7 4 2 5 9 9 9 4 Anti-sigma-K factor rskA Cu-binding_MopE PF11617.8 CDJ56955.1 - 0.17 12.0 1.5 0.4 10.9 1.5 1.6 1 0 0 1 1 1 0 Putative metal-binding motif Smr PF01713.21 CDJ56955.1 - 0.33 11.3 5.2 0.17 12.2 1.6 2.5 2 0 0 2 2 2 0 Smr domain SARAF PF06682.12 CDJ56956.1 - 0.00048 19.9 6.3 0.00048 19.9 6.3 3.0 3 1 0 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Cwf_Cwc_15 PF04889.12 CDJ56957.1 - 3.5e-05 23.7 1.8 3.5e-05 23.7 1.8 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CDJ56957.1 - 0.0069 16.0 9.5 0.0069 16.0 9.5 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1041 PF06292.17 CDJ56957.1 - 3.9 7.9 12.2 3.9 7.9 1.9 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1041) AAA_23 PF13476.6 CDJ56957.1 - 5.9 7.3 13.2 4.3 7.8 2.1 2.1 2 0 0 2 2 2 0 AAA domain PDDEXK_6 PF04720.12 CDJ56957.1 - 8 6.3 13.0 12 5.8 5.4 2.2 2 0 0 2 2 2 0 PDDEXK-like family of unknown function TCP PF03634.13 CDJ56957.1 - 9.6 6.8 16.9 0.65 10.6 6.1 2.4 2 0 0 2 2 2 0 TCP family transcription factor DnaJ PF00226.31 CDJ56958.1 - 4.1e-23 81.3 0.9 6.7e-23 80.6 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain Apt1 PF10351.9 CDJ56958.1 - 0.16 10.8 6.6 0.2 10.4 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ56958.1 - 0.36 9.3 8.3 0.43 9.1 8.3 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 CDJ56958.1 - 0.48 9.6 14.3 0.64 9.2 14.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CDJ56958.1 - 1.7 7.3 5.2 2.3 6.9 5.2 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 CDJ56958.1 - 2.3 6.6 7.5 2.7 6.4 7.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ56958.1 - 3.4 7.6 8.1 4.2 7.3 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ56958.1 - 9.1 3.2 8.3 11 3.0 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP2C PF00481.21 CDJ56959.1 - 4.6e-12 46.1 0.0 5.4e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C zf-RING_10 PF16685.5 CDJ56960.1 - 0.012 15.7 8.1 0.024 14.8 8.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 CDJ56960.1 - 0.032 14.1 13.0 0.058 13.3 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DWNN PF08783.11 CDJ56960.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 DWNN domain zf-RING_5 PF14634.6 CDJ56960.1 - 0.21 11.6 11.8 0.71 9.9 11.8 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ56960.1 - 0.29 11.0 13.3 0.53 10.2 13.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ56960.1 - 0.35 11.2 13.6 0.75 10.2 13.6 1.5 1 0 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.11 CDJ56960.1 - 3.4 7.6 5.7 7.1 6.6 5.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 CDJ56960.1 - 4.9 7.0 11.7 12 5.8 11.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain V_ATPase_I PF01496.19 CDJ56961.1 - 2e-251 836.5 0.0 2.3e-251 836.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PGA2 PF07543.12 CDJ56961.1 - 0.084 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 ISK_Channel PF02060.15 CDJ56961.1 - 7.5 6.3 9.8 0.64 9.8 0.9 2.8 2 0 0 2 2 2 0 Slow voltage-gated potassium channel BaxI_1 PF12811.7 CDJ56962.1 - 0.016 14.8 4.3 0.016 14.8 4.3 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like ENTH PF01417.20 CDJ56965.1 - 2e-26 92.5 0.0 2.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDJ56965.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Asp_protease PF09668.10 CDJ56967.1 - 7.2e-50 167.9 0.0 1.1e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDJ56967.1 - 3.1e-19 69.3 0.0 6e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 CDJ56967.1 - 1.2e-09 37.8 0.0 2.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 CDJ56967.1 - 8e-09 36.0 0.0 1.7e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDJ56967.1 - 2.3e-05 24.1 0.1 7.4e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CDJ56967.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Rad60-SLD PF11976.8 CDJ56967.1 - 0.03 14.2 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Surface_antigen PF11054.8 CDJ56968.1 - 2.5e-30 105.9 7.1 3.6e-30 105.4 7.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen EF1G PF00647.19 CDJ56968.1 - 0.14 12.2 0.0 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Surface_antigen PF11054.8 CDJ56969.1 - 2.9e-29 102.5 3.9 3.6e-29 102.2 3.9 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ56970.1 - 9.4e-31 107.3 8.2 1.2e-30 107.0 8.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ56971.1 - 7.8e-28 97.8 9.2 1.1e-27 97.2 9.2 1.2 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Defensin_propep PF00879.18 CDJ56971.1 - 0.14 12.5 0.4 0.46 10.8 0.4 1.8 1 0 0 1 1 1 0 Defensin propeptide Surface_antigen PF11054.8 CDJ56972.1 - 2e-28 99.7 5.6 1.3e-19 70.8 2.1 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen TMEM171 PF15471.6 CDJ56972.1 - 0.38 9.7 3.7 0.56 9.1 3.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 adh_short_C2 PF13561.6 CDJ56973.1 - 1.5e-30 106.5 0.1 1.6e-30 106.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ56973.1 - 4.1e-15 55.7 0.3 5.1e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Seadorna_Vp10 PF07322.11 CDJ56973.1 - 0.013 15.0 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus Vp10 Cas_Csx8 PF09657.10 CDJ56973.1 - 0.091 11.7 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) DUF2205 PF10224.9 CDJ56974.1 - 3.6e-05 23.7 2.4 3.6e-05 23.7 2.4 2.3 2 0 0 2 2 1 1 Short coiled-coil protein YabA PF06156.13 CDJ56974.1 - 0.0017 18.9 13.4 0.0025 18.4 13.0 1.5 1 1 0 1 1 1 1 Initiation control protein YabA FlaC_arch PF05377.11 CDJ56974.1 - 0.0025 18.1 1.3 0.0058 17.0 1.3 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Macoilin PF09726.9 CDJ56974.1 - 0.0036 15.9 12.1 0.0048 15.5 12.1 1.2 1 0 0 1 1 1 1 Macoilin family ALMT PF11744.8 CDJ56974.1 - 0.0061 15.4 6.1 0.0069 15.3 6.1 1.0 1 0 0 1 1 1 1 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDJ56974.1 - 0.0088 14.0 6.3 0.0096 13.9 6.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cnn_1N PF07989.11 CDJ56974.1 - 0.013 15.7 2.4 0.013 15.7 2.4 2.6 1 1 2 3 3 2 0 Centrosomin N-terminal motif 1 TFIIA PF03153.13 CDJ56974.1 - 0.013 15.5 30.4 0.015 15.3 30.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L29 PF00831.23 CDJ56974.1 - 0.026 14.5 0.1 0.026 14.5 0.1 3.1 1 1 1 2 2 1 0 Ribosomal L29 protein bZIP_1 PF00170.21 CDJ56974.1 - 0.028 14.5 1.8 0.028 14.5 1.8 2.0 2 1 0 2 2 1 0 bZIP transcription factor Ribonuc_P_40 PF08584.11 CDJ56974.1 - 0.042 13.1 1.7 0.047 13.0 1.7 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit SKA1 PF07160.12 CDJ56974.1 - 0.048 13.5 12.5 0.059 13.2 12.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 OmpH PF03938.14 CDJ56974.1 - 0.085 13.2 24.5 0.14 12.4 24.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 CDJ56974.1 - 0.095 11.8 10.9 0.12 11.4 10.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF913 PF06025.12 CDJ56974.1 - 0.13 11.2 5.9 0.15 11.0 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-F_leu_zip PF10473.9 CDJ56974.1 - 0.16 12.0 18.4 0.27 11.3 18.2 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2813 PF11398.8 CDJ56974.1 - 0.66 9.2 9.9 0.84 8.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) CENP-H PF05837.12 CDJ56974.1 - 0.66 10.4 17.6 0.39 11.1 15.5 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Lin-8 PF03353.15 CDJ56974.1 - 0.77 9.3 13.4 0.94 9.0 13.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ56974.1 - 1.1 7.9 14.9 1.3 7.7 14.9 1.2 1 0 0 1 1 1 0 Presenilin Mod_r PF07200.13 CDJ56974.1 - 1.2 9.3 22.4 1.8 8.7 22.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 CDJ56974.1 - 1.9 7.8 21.2 2.8 7.2 21.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PRR18 PF15671.5 CDJ56974.1 - 2 8.2 13.7 2.8 7.8 13.7 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 PAT1 PF09770.9 CDJ56974.1 - 2.1 6.5 22.8 2.2 6.5 22.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.10 CDJ56974.1 - 2.1 8.6 14.9 2.7 8.2 14.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FemAB PF02388.16 CDJ56974.1 - 2.7 6.7 10.2 3.6 6.4 10.2 1.2 1 0 0 1 1 1 0 FemAB family GREB1 PF15782.5 CDJ56974.1 - 3.3 4.7 13.5 3.6 4.6 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ56974.1 - 3.3 7.0 6.2 3.7 6.9 6.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAT1 PF06391.13 CDJ56974.1 - 3.3 7.5 17.6 5.1 6.9 17.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TMF_DNA_bd PF12329.8 CDJ56974.1 - 3.5 7.7 14.8 0.16 12.0 7.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding JIP_LZII PF16471.5 CDJ56974.1 - 3.8 7.8 8.4 0.31 11.2 2.2 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Neur_chan_memb PF02932.16 CDJ56974.1 - 3.8 7.5 7.6 4.6 7.2 7.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpecificRecomb PF10136.9 CDJ56974.1 - 3.9 5.7 8.2 5 5.3 8.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase Prominin PF05478.11 CDJ56974.1 - 4.1 5.2 10.9 5.5 4.8 10.9 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 CDJ56974.1 - 4.9 5.7 9.3 6.6 5.2 9.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A MCU PF04678.13 CDJ56974.1 - 7.5 6.6 8.1 12 5.9 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1980 PF09323.10 CDJ56974.1 - 7.8 6.4 6.7 12 5.8 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Baculo_PP31 PF05311.11 CDJ56974.1 - 9.9 5.6 11.7 9.8 5.6 10.9 1.4 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PPR PF01535.20 CDJ56975.1 - 0.039 14.2 0.1 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 PPR repeat Vpu PF00558.19 CDJ56975.1 - 0.16 11.8 1.1 0.46 10.3 1.1 1.7 1 0 0 1 1 1 0 Vpu protein CENP-F_leu_zip PF10473.9 CDJ56976.1 - 0.055 13.5 12.7 0.063 13.3 11.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 CDJ56976.1 - 0.17 12.0 10.9 0.35 11.0 10.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NYD-SP28_assoc PF14775.6 CDJ56976.1 - 2.7 8.2 8.0 0.3 11.2 0.4 2.9 2 1 1 3 3 3 0 Sperm tail C-terminal domain FapA PF03961.13 CDJ56976.1 - 4.3 5.8 5.9 6.3 5.3 5.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prenyltransf PF01255.19 CDJ56977.1 - 8.2e-44 149.8 4.9 3.2e-42 144.6 4.9 2.1 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NPR3 PF03666.13 CDJ56977.1 - 0.0017 17.3 6.8 0.002 17.0 6.8 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Miga PF10265.9 CDJ56977.1 - 0.028 13.4 11.5 0.04 12.9 11.5 1.2 1 0 0 1 1 1 0 Mitoguardin SID-1_RNA_chan PF13965.6 CDJ56977.1 - 0.037 12.5 0.9 0.044 12.2 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ56977.1 - 0.061 12.4 6.1 0.08 12.0 6.1 1.3 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 CDJ56977.1 - 0.067 12.2 6.3 0.093 11.7 6.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAR2 PF05282.11 CDJ56977.1 - 0.068 12.6 11.0 0.12 11.8 11.0 1.3 1 0 0 1 1 1 0 AAR2 protein Membralin PF09746.9 CDJ56977.1 - 0.17 10.9 6.5 0.25 10.3 6.5 1.3 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CDJ56977.1 - 0.18 8.9 15.5 0.21 8.7 15.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paramyxo_ncap PF00973.19 CDJ56977.1 - 0.28 10.1 17.8 0.39 9.6 17.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein EOS1 PF12326.8 CDJ56977.1 - 0.32 10.9 4.4 0.7 9.8 4.4 1.6 1 0 0 1 1 1 0 N-glycosylation protein DcuA_DcuB PF03605.14 CDJ56977.1 - 0.58 9.0 3.7 0.42 9.4 0.9 1.9 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Hid1 PF12722.7 CDJ56977.1 - 0.68 8.0 18.2 0.95 7.5 18.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RskA PF10099.9 CDJ56977.1 - 0.82 9.9 31.0 1.7 8.9 5.1 3.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Serinc PF03348.15 CDJ56977.1 - 0.82 8.5 8.2 1.3 7.9 8.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 CDJ56977.1 - 0.83 8.8 4.9 1.1 8.4 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 CDJ56977.1 - 0.87 8.8 9.6 1.5 8.0 9.6 1.4 1 0 0 1 1 1 0 Prim-pol family 5 ABC2_membrane_2 PF12679.7 CDJ56977.1 - 1.1 8.5 3.3 1.5 8.0 3.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Otopetrin PF03189.13 CDJ56977.1 - 1.2 7.9 4.6 1.6 7.5 4.6 1.3 1 0 0 1 1 1 0 Otopetrin MDM10 PF12519.8 CDJ56977.1 - 1.3 7.8 11.7 1.8 7.3 11.7 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 V_ATPase_I PF01496.19 CDJ56977.1 - 1.4 6.7 15.5 2.2 6.1 15.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ56977.1 - 1.6 8.5 12.1 2.8 7.7 12.1 1.4 1 0 0 1 1 1 0 Connexin Cellulose_synt PF03552.14 CDJ56977.1 - 2 6.8 5.0 2.5 6.5 5.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Endostatin PF06482.11 CDJ56977.1 - 2.7 7.4 17.4 2.6 7.5 16.1 1.4 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1980 PF09323.10 CDJ56977.1 - 2.7 7.8 9.7 5.6 6.8 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2828 PF11443.8 CDJ56977.1 - 3.2 5.7 15.8 6 4.8 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) OATP PF03137.20 CDJ56977.1 - 3.4 5.8 7.3 5.8 5.1 7.3 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CSG2 PF16965.5 CDJ56977.1 - 4.2 6.2 8.2 6.2 5.7 8.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_S64 PF08192.11 CDJ56977.1 - 4.3 5.7 17.1 5.4 5.4 17.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 AAA_23 PF13476.6 CDJ56977.1 - 5.1 7.5 22.4 0.11 13.0 13.2 2.2 2 0 0 2 2 2 0 AAA domain Peroxin-13_N PF04088.13 CDJ56977.1 - 6.1 7.1 8.1 15 5.8 8.1 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Plasmodium_Vir PF05795.11 CDJ56977.1 - 7.4 5.9 11.6 12 5.2 11.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein O-antigen_lig PF13425.6 CDJ56977.1 - 9.2 4.9 7.2 14 4.4 7.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NTP_transferase PF00483.23 CDJ56978.1 - 9e-29 100.8 0.8 2.4e-20 73.2 0.1 2.1 2 0 0 2 2 2 2 Nucleotidyl transferase NTP_transf_3 PF12804.7 CDJ56978.1 - 9.1e-08 32.6 7.2 9.1e-08 32.6 7.2 2.2 1 1 1 2 2 2 1 MobA-like NTP transferase domain SOG2 PF10428.9 CDJ56978.1 - 0.28 10.3 6.6 0.37 9.9 6.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DHHC PF01529.20 CDJ56979.1 - 9.8e-28 96.9 13.0 7e-27 94.2 10.1 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase MOLO1 PF17175.4 CDJ56980.1 - 1e-26 93.4 0.0 1.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ56980.1 - 7.6e-07 29.3 0.0 3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 TPM domain PNK3P PF08645.11 CDJ56981.1 - 0.0044 16.7 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF2608 PF11019.8 CDJ56981.1 - 0.12 11.9 0.8 0.24 10.8 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 CDJ56981.1 - 0.21 11.7 1.1 0.81 9.7 1.1 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAM110_C PF14160.6 CDJ56981.1 - 0.78 10.8 3.5 1.3 10.1 0.0 2.4 2 0 0 2 2 2 0 Centrosome-associated C terminus RRM_1 PF00076.22 CDJ56982.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSB_motif PF16294.5 CDJ56982.1 - 1.5 9.1 10.5 0.26 11.6 1.6 2.4 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif DNA_pol_B_exo1 PF03104.19 CDJ56983.1 - 3.9e-42 144.6 0.0 7.3e-41 140.4 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 CDJ56983.1 - 3.8e-22 78.4 0.0 2.1e-20 72.7 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.9 CDJ56983.1 - 9.9e-08 31.9 0.0 0.00064 19.5 0.0 2.7 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B PF00136.21 CDJ56983.1 - 4.3e-07 29.0 0.4 2.8e-06 26.3 0.2 2.4 3 0 0 3 3 3 1 DNA polymerase family B NAD_binding_8 PF13450.6 CDJ56983.1 - 0.058 13.6 1.7 0.27 11.5 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain RNase_H_2 PF13482.6 CDJ56983.1 - 0.083 12.9 0.2 1 9.3 0.0 2.8 3 0 0 3 3 3 0 RNase_H superfamily zinc_ribbon_2 PF13240.6 CDJ56983.1 - 6.8 6.6 6.3 3.3 7.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RRM_1 PF00076.22 CDJ56984.1 - 4.4e-05 23.2 0.0 7.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDJ56984.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 RL domain RRM_7 PF16367.5 CDJ56984.1 - 0.15 12.2 0.0 0.55 10.4 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif UDPGP PF01704.18 CDJ56985.1 - 4.1e-15 55.3 0.2 1.5e-13 50.2 0.0 2.8 3 1 0 3 3 2 1 UTP--glucose-1-phosphate uridylyltransferase Pex14_N PF04695.13 CDJ56985.1 - 0.0014 19.3 2.6 0.0014 19.3 2.6 2.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 CDJ56985.1 - 0.0036 17.4 21.4 0.0093 16.0 8.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ56985.1 - 0.0061 15.6 11.0 0.5 9.2 6.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) CCDC53 PF10152.9 CDJ56985.1 - 0.14 12.6 5.3 1.2 9.5 0.2 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 CDJ56985.1 - 0.2 10.4 3.2 1 8.0 0.1 2.1 2 0 0 2 2 2 0 Presenilin Med15 PF09606.10 CDJ56985.1 - 0.29 9.8 26.1 0.22 10.2 1.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.6 CDJ56985.1 - 1.1 8.5 7.5 4.5 6.5 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) TERB2 PF15101.6 CDJ56985.1 - 1.2 9.1 8.1 1.8 8.6 2.1 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 MMR1 PF08505.10 CDJ56985.1 - 2.5 8.3 10.4 0.24 11.6 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CTU2 PF10288.9 CDJ56985.1 - 3.3 8.0 7.7 4.1 7.7 2.4 2.4 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 RED_N PF07808.13 CDJ56985.1 - 7.8 6.0 11.0 1.1 8.7 0.2 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region AAA_23 PF13476.6 CDJ56985.1 - 9.9 6.6 13.0 1.4 9.4 1.4 2.2 2 0 0 2 2 2 0 AAA domain Tr-sialidase_C PF11052.8 CDJ56986.1 - 0.43 10.8 9.4 5.5 7.2 0.4 2.5 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal Dicty_REP PF05086.12 CDJ56986.1 - 0.46 8.4 0.6 0.62 8.0 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GTP_EFTU PF00009.27 CDJ56987.1 - 6.3e-05 22.6 0.3 6.3e-05 22.6 0.3 3.8 3 2 0 4 4 4 2 Elongation factor Tu GTP binding domain IF2_N PF04760.15 CDJ56987.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Dynamin_N PF00350.23 CDJ56987.1 - 0.043 13.9 0.0 0.043 13.9 0.0 3.6 3 1 1 4 4 4 0 Dynamin family MMR_HSR1 PF01926.23 CDJ56987.1 - 0.061 13.4 0.0 0.25 11.4 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase RskA PF10099.9 CDJ56989.1 - 5e-06 26.9 6.0 5e-06 26.9 6.0 4.1 3 1 0 3 3 3 1 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ56989.1 - 0.016 15.0 3.7 0.016 15.0 3.7 2.8 3 0 0 3 3 3 0 Connexin CDC45 PF02724.14 CDJ56989.1 - 0.034 12.4 5.0 0.051 11.9 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Dynamin_N PF00350.23 CDJ56989.1 - 0.19 11.8 5.5 0.19 11.8 2.5 2.0 2 0 0 2 2 2 0 Dynamin family EphA2_TM PF14575.6 CDJ56989.1 - 0.63 11.0 10.5 1.6 9.7 0.4 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SLC12 PF03522.15 CDJ56989.1 - 0.8 8.7 15.6 0.37 9.8 11.7 2.0 2 0 0 2 2 2 0 Solute carrier family 12 ANAPC_CDC26 PF10471.9 CDJ56989.1 - 0.87 10.5 48.8 0.079 13.8 4.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 AIF_C PF14721.6 CDJ56989.1 - 1.4 9.3 11.2 0.42 11.0 1.1 2.7 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spt20 PF12090.8 CDJ56989.1 - 2 8.0 60.8 0.18 11.4 19.9 3.1 3 0 0 3 3 3 0 Spt20 family DUF4199 PF13858.6 CDJ56989.1 - 2.1 8.7 8.2 8.7 6.7 2.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF2828 PF11443.8 CDJ56989.1 - 3.4 5.6 11.1 1.7 6.6 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 CDJ56989.1 - 3.6 6.3 14.7 15 4.3 0.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DHHW PF14286.6 CDJ56989.1 - 3.7 6.8 9.5 3 7.1 8.0 1.4 1 1 1 2 2 2 0 DHHW protein DUF4471 PF14740.6 CDJ56989.1 - 4.1 6.5 10.4 1.8 7.7 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Serinc PF03348.15 CDJ56989.1 - 4.1 6.2 5.9 0.97 8.3 1.1 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) OATP PF03137.20 CDJ56989.1 - 8.6 4.5 11.8 0.32 9.2 1.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MORN PF02493.20 CDJ56990.1 - 9.3e-24 81.9 49.2 3.4e-06 26.6 0.5 7.2 7 0 0 7 7 7 6 MORN repeat BAF1_ABF1 PF04684.13 CDJ56990.1 - 0.0054 15.8 27.4 0.0054 15.8 27.4 3.0 2 1 1 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor Ion_trans PF00520.31 CDJ56991.1 - 0.00067 19.0 9.4 0.00087 18.6 9.4 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5090 PF17009.5 CDJ56991.1 - 1.3 8.9 6.4 2.3 8.1 6.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) TPR_8 PF13181.6 CDJ56993.1 - 0.14 12.5 0.2 27 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ56993.1 - 0.16 12.1 3.4 4 7.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 CDJ56996.1 - 0.076 12.4 11.4 0.83 9.0 11.4 2.0 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 CDJ56996.1 - 0.31 11.1 7.2 0.79 9.8 0.7 3.1 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain PGA2 PF07543.12 CDJ56997.1 - 0.014 15.4 8.2 0.044 13.8 8.2 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 NitrOD1 PF18549.1 CDJ56999.1 - 0.00044 20.1 0.7 3.1 7.9 0.1 3.4 3 0 0 3 3 3 2 Nitrosopumilus output domain 1 MT0933_antitox PF14013.6 CDJ56999.1 - 0.0038 17.5 1.1 3.7 7.9 0.0 3.0 2 1 1 3 3 3 2 MT0933-like antitoxin protein DHR10 PF18595.1 CDJ56999.1 - 0.02 14.9 2.8 15 5.7 0.2 3.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain RasGEF PF00617.19 CDJ56999.1 - 0.035 14.3 0.0 40 4.4 0.0 3.3 3 0 0 3 3 3 0 RasGEF domain DUF4164 PF13747.6 CDJ56999.1 - 0.087 13.1 0.3 7.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MRPL52 PF18699.1 CDJ56999.1 - 0.12 12.5 0.8 30 4.9 0.0 2.9 3 0 0 3 3 3 0 Mitoribosomal protein mL52 GARP PF16731.5 CDJ56999.1 - 0.41 10.3 1.9 13 5.4 0.1 2.7 2 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma PMEI PF04043.15 CDJ56999.1 - 0.77 10.1 3.2 26 5.2 2.1 3.1 2 2 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Gal4_dimer PF03902.13 CDJ56999.1 - 1.4 9.1 4.9 24 5.2 0.3 2.8 2 0 0 2 2 2 0 Gal4-like dimerisation domain Spt20 PF12090.8 CDJ57001.1 - 1.5e-06 28.0 16.1 1.5e-06 28.0 16.1 1.8 2 0 0 2 2 2 1 Spt20 family MAP65_ASE1 PF03999.12 CDJ57001.1 - 0.0096 14.7 15.9 0.012 14.4 15.9 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Roughex PF06020.11 CDJ57001.1 - 0.062 12.4 8.1 0.1 11.7 8.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SPX PF03105.19 CDJ57001.1 - 0.14 12.0 20.1 0.17 11.7 20.1 1.1 1 0 0 1 1 1 0 SPX domain NST1 PF13945.6 CDJ57001.1 - 0.9 9.6 28.4 0.16 12.1 21.9 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF853 PF05872.12 CDJ57001.1 - 1.3 7.6 5.4 1.5 7.3 5.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Membralin PF09746.9 CDJ57001.1 - 3.5 6.6 7.7 4.8 6.1 7.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein FliD_N PF02465.18 CDJ57001.1 - 4.5 8.0 21.5 0.084 13.6 12.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SLC12 PF03522.15 CDJ57001.1 - 4.8 6.1 14.8 0.42 9.6 10.7 1.3 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ57001.1 - 4.8 7.2 16.7 0.54 10.3 12.4 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.13 CDJ57001.1 - 4.9 5.4 17.4 0.03 12.7 8.7 1.7 2 0 0 2 2 2 0 Menin CLN3 PF02487.17 CDJ57001.1 - 5.3 6.0 6.6 7.4 5.5 6.6 1.3 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 CDJ57001.1 - 6 7.0 15.6 2 8.6 10.1 2.3 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CDJ57001.1 - 9.6 6.1 29.3 13 5.6 29.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 CDJ57001.1 - 9.7 6.4 17.7 1.4 9.2 13.0 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR AMMECR1 PF01871.17 CDJ57002.1 - 4.9e-35 120.6 0.0 4.9e-35 120.6 0.0 2.5 3 1 0 3 3 3 1 AMMECR1 Exonuc_VII_L PF02601.15 CDJ57003.1 - 0.00013 21.6 3.4 0.00013 21.6 3.4 11.6 6 3 5 11 11 11 3 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 CDJ57003.1 - 0.0013 17.8 26.5 0.0013 17.8 26.5 13.5 11 4 2 13 13 13 1 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ57003.1 - 0.0062 16.6 0.0 0.0062 16.6 0.0 30.2 13 7 13 26 26 26 2 Unstructured region C-term to UIM in Ataxin3 Scs3p PF10261.9 CDJ57003.1 - 0.51 9.8 0.0 0.51 9.8 0.0 9.8 10 5 2 12 12 12 0 Inositol phospholipid synthesis and fat-storage-inducing TM RskA PF10099.9 CDJ57004.1 - 0.004 17.5 0.4 0.004 17.5 0.4 4.8 2 2 1 3 3 3 1 Anti-sigma-K factor rskA SPX PF03105.19 CDJ57004.1 - 7.6 6.3 45.0 0.92 9.4 10.9 2.7 2 1 0 2 2 2 0 SPX domain Peptidase_C54 PF03416.19 CDJ57005.1 - 3.5e-12 46.3 0.1 1.5e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 Peptidase family C54 SR-25 PF10500.9 CDJ57005.1 - 0.00015 21.4 9.1 0.00015 21.4 9.1 9.9 6 3 2 9 9 9 2 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ57005.1 - 0.00052 19.8 1.3 0.00052 19.8 1.3 6.4 5 2 1 6 6 6 1 Cwf15/Cwc15 cell cycle control protein RskA PF10099.9 CDJ57005.1 - 0.00092 19.5 3.3 0.00092 19.5 3.3 10.1 2 2 4 6 6 6 2 Anti-sigma-K factor rskA NST1 PF13945.6 CDJ57005.1 - 0.0015 18.6 0.5 0.0015 18.6 0.5 8.8 7 3 1 9 9 9 1 Salt tolerance down-regulator SUIM_assoc PF16619.5 CDJ57005.1 - 0.0055 16.7 5.4 0.0055 16.7 5.4 15.7 9 4 2 11 11 11 2 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 CDJ57007.1 - 0.0011 19.0 22.1 0.41 11.0 0.1 8.7 9 0 0 9 9 9 2 HEAT repeat Kinocilin PF15033.6 CDJ57007.1 - 0.05 13.3 0.0 8.9 6.0 0.0 3.4 3 0 0 3 3 3 0 Kinocilin protein TFCD_C PF12612.8 CDJ57007.1 - 2.1 8.1 11.1 7.4 6.4 0.2 4.4 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal SUIM_assoc PF16619.5 CDJ57009.1 - 0.12 12.5 7.5 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PCI PF01399.27 CDJ57011.1 - 5.1e-11 43.0 2.0 5.2e-11 43.0 0.4 1.9 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CDJ57011.1 - 0.00053 19.7 0.5 0.001 18.8 0.5 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Trypan_PARP PF05887.11 CDJ57011.1 - 4.8 7.2 10.2 0.04 13.9 1.3 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.15 CDJ57011.1 - 9.2 4.4 7.0 23 3.1 4.3 2.1 2 0 0 2 2 2 0 Atrophin-1 family RskA PF10099.9 CDJ57012.1 - 0.00024 21.5 11.0 0.00024 21.5 11.0 14.0 2 2 7 10 10 10 4 Anti-sigma-K factor rskA Hydrolase_3 PF08282.12 CDJ57013.1 - 9.5e-36 123.8 0.0 4.3e-20 72.5 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDJ57013.1 - 2.4e-07 31.3 0.9 0.05 13.9 1.1 3.1 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ57013.1 - 4.5e-07 29.7 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Rsa3 PF14615.6 CDJ57014.1 - 0.2 11.2 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Spore_III_AB PF09548.10 CDJ57015.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.3 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF572 PF04502.13 CDJ57015.1 - 1.2 8.7 20.7 1.9 8.0 20.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dscam_C PF12355.8 CDJ57016.1 - 0.0027 18.6 1.5 0.0049 17.8 1.5 1.3 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal ACDC PF14733.6 CDJ57017.1 - 7.5e-17 61.4 0.1 7.5e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ57017.1 - 1.4e-09 38.0 0.3 1.4e-09 38.0 0.3 2.3 2 0 0 2 2 2 1 AP2 domain cNMP_binding PF00027.29 CDJ57019.1 - 0.0002 21.4 0.0 14 5.8 0.0 4.5 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Ephrin_rec_like PF07699.13 CDJ57020.1 - 4.3e-05 23.2 17.3 0.00011 21.8 6.8 31.2 19 8 16 35 35 35 23 Putative ephrin-receptor like Serglycin PF04360.12 CDJ57021.1 - 0.07 13.1 0.2 0.07 13.1 0.2 2.1 2 0 0 2 2 2 0 Serglycin Sec62 PF03839.16 CDJ57021.1 - 0.098 12.2 1.1 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 ASFV_J13L PF05568.11 CDJ57021.1 - 3.5 7.3 8.6 11 5.8 8.6 1.8 1 0 0 1 1 1 0 African swine fever virus J13L protein Pentapeptide_4 PF13599.6 CDJ57022.1 - 1.7e-05 24.9 0.0 0.17 12.1 0.0 2.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Lamprin PF06403.11 CDJ57022.1 - 0.0041 17.1 0.7 0.096 12.7 0.4 2.0 1 1 1 2 2 2 2 Lamprin DUF4470 PF14737.6 CDJ57023.1 - 0.0023 18.1 9.9 0.039 14.1 9.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) CDC45 PF02724.14 CDJ57023.1 - 0.024 12.9 36.0 0.034 12.5 36.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Caldesmon PF02029.15 CDJ57023.1 - 0.37 9.5 47.0 0.47 9.2 47.0 1.1 1 0 0 1 1 1 0 Caldesmon SDA1 PF05285.12 CDJ57023.1 - 1.1 8.6 40.2 1.5 8.2 40.2 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 CDJ57023.1 - 3.9 5.5 40.1 5.2 5.1 40.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.13 CDJ57023.1 - 5.8 6.4 40.5 7.5 6.1 40.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Trypan_PARP PF05887.11 CDJ57023.1 - 7.1 6.6 6.5 13 5.8 6.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.9 CDJ57024.1 - 0.014 14.0 19.5 0.016 13.8 19.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4602 PF15375.6 CDJ57024.1 - 0.024 15.0 2.5 0.024 15.0 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) SRP-alpha_N PF04086.13 CDJ57024.1 - 0.17 11.7 13.1 0.2 11.6 13.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LAP1C PF05609.12 CDJ57024.1 - 0.31 10.1 14.9 0.35 9.9 14.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4471 PF14740.6 CDJ57024.1 - 0.33 10.1 9.7 0.83 8.8 9.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) DUF2052 PF09747.9 CDJ57024.1 - 0.37 10.9 9.9 0.53 10.4 9.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 CDJ57024.1 - 0.42 9.4 18.3 0.49 9.2 18.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PNISR PF15996.5 CDJ57024.1 - 0.79 10.0 20.0 1.1 9.4 20.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BUD22 PF09073.10 CDJ57024.1 - 0.81 9.0 23.3 0.95 8.7 23.3 1.0 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 CDJ57024.1 - 1 8.3 9.5 1.1 8.2 9.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CDJ57024.1 - 1.2 7.9 17.3 1.5 7.5 17.3 1.1 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 CDJ57024.1 - 1.7 7.5 12.6 2 7.3 12.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF2681 PF10883.8 CDJ57024.1 - 1.7 9.1 9.7 0.94 9.9 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Neur_chan_memb PF02932.16 CDJ57024.1 - 1.9 8.5 9.0 2.9 7.9 9.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-3 PF04882.12 CDJ57024.1 - 1.9 7.4 14.4 2.3 7.1 14.4 1.3 1 0 0 1 1 1 0 Peroxin-3 GREB1 PF15782.5 CDJ57024.1 - 2.5 5.1 14.4 2.8 5.0 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ57024.1 - 2.8 6.0 15.6 3 5.8 15.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CDJ57024.1 - 2.9 6.1 13.0 3.5 5.8 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 CDJ57024.1 - 5.9 6.7 21.1 6.9 6.5 21.1 1.0 1 0 0 1 1 1 0 SPX domain CPSF100_C PF13299.6 CDJ57024.1 - 5.9 7.0 14.4 48 4.1 14.4 1.9 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal QWRF PF04484.12 CDJ57024.1 - 6.9 6.3 18.2 8.8 6.0 18.2 1.1 1 0 0 1 1 1 0 QWRF family DUF2203 PF09969.9 CDJ57025.1 - 0.33 11.7 2.9 0.15 12.8 0.7 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cwf_Cwc_15 PF04889.12 CDJ57025.1 - 1.1 8.9 8.6 1.4 8.6 8.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ57025.1 - 1.2 8.9 12.3 1.5 8.7 12.3 1.1 1 0 0 1 1 1 0 SPX domain BAF1_ABF1 PF04684.13 CDJ57025.1 - 1.5 7.8 12.6 1.7 7.6 12.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.9 CDJ57025.1 - 1.9 7.0 15.3 2.5 6.6 15.3 1.2 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 CDJ57025.1 - 2.2 8.9 17.1 2.1 8.9 9.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain SKA1 PF07160.12 CDJ57025.1 - 2.3 8.0 8.9 1.3 8.8 1.3 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Presenilin PF01080.17 CDJ57025.1 - 6.6 5.4 7.8 7.7 5.2 7.8 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ57025.1 - 9.2 5.0 12.3 12 4.6 12.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ57028.1 - 0.00048 20.5 0.2 0.00048 20.5 0.2 11.4 3 1 6 9 9 9 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ57028.1 - 0.0025 16.9 0.1 0.0025 16.9 0.1 5.6 2 1 2 5 5 5 1 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 CDJ57029.1 - 0.29 9.0 6.0 0.33 8.8 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 CDJ57029.1 - 0.5 10.3 28.6 0.65 9.9 28.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ57029.1 - 1.2 9.8 13.4 1.9 9.1 13.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM222A PF15258.6 CDJ57029.1 - 8 5.4 24.9 9.5 5.2 24.9 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Mpp10 PF04006.12 CDJ57030.1 - 4.1e-34 118.0 208.2 1.2e-22 80.2 9.5 6.2 2 2 3 5 5 5 3 Mpp10 protein RskA PF10099.9 CDJ57031.1 - 0.22 11.8 28.7 0.24 11.7 2.7 3.8 4 0 0 4 4 4 0 Anti-sigma-K factor rskA GNAT_acetyltr_2 PF13718.6 CDJ57032.1 - 0.006 16.0 0.0 0.006 16.0 0.0 3.1 4 0 0 4 4 4 1 GNAT acetyltransferase 2 Pex24p PF06398.11 CDJ57032.1 - 0.48 9.3 2.7 8 5.3 0.0 2.3 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Adaptin_binding PF10199.9 CDJ57032.1 - 5.3 7.7 20.7 5.3 7.7 2.2 3.6 2 2 2 4 4 4 0 Alpha and gamma adaptin binding protein p34 ubiquitin PF00240.23 CDJ57034.1 - 6.9e-22 77.0 0.6 7.8e-22 76.8 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ57034.1 - 5.5e-09 35.7 0.2 7.1e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ57034.1 - 9.8e-06 25.9 0.5 4.9e-05 23.7 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CDJ57034.1 - 0.016 15.7 0.2 0.018 15.6 0.2 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ57034.1 - 0.023 14.8 0.1 0.069 13.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDJ57034.1 - 0.024 15.0 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain RCC1 PF00415.18 CDJ57037.1 - 2e-32 111.5 22.4 2e-09 38.0 0.1 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ57037.1 - 1e-18 66.6 36.0 4.4e-05 23.2 0.6 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Spt20 PF12090.8 CDJ57037.1 - 0.0011 18.7 7.3 0.0011 18.7 7.3 7.9 4 2 2 7 7 7 2 Spt20 family Ribosomal_60s PF00428.19 CDJ57037.1 - 0.0074 16.9 7.4 0.0074 16.9 7.4 16.8 4 2 9 13 13 13 1 60s Acidic ribosomal protein NPL PF17800.1 CDJ57037.1 - 3 8.5 0.0 3 8.5 0.0 4.0 2 1 0 2 2 2 0 Nucleoplasmin-like domain ALMT PF11744.8 CDJ57039.1 - 0.19 10.6 0.2 0.26 10.1 0.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Roughex PF06020.11 CDJ57039.1 - 0.21 10.6 2.4 0.33 10.0 2.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein MIG-14_Wnt-bd PF06664.12 CDJ57040.1 - 0.0016 17.8 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion LAP1C PF05609.12 CDJ57040.1 - 0.0077 15.4 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Pex14_N PF04695.13 CDJ57040.1 - 0.062 14.0 5.8 0.36 11.5 1.1 3.0 2 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_ligase_A_N PF04675.14 CDJ57040.1 - 0.085 13.2 0.5 1.4 9.3 0.0 2.5 3 0 0 3 3 3 0 DNA ligase N terminus DUF4778 PF16008.5 CDJ57040.1 - 8.3 6.4 8.6 13 5.7 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Brix PF04427.18 CDJ57041.1 - 3.5e-16 59.9 0.1 6.3e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 CDJ57041.1 - 0.00035 20.7 25.7 0.00044 20.4 25.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit tRNA_lig_CPD PF08302.11 CDJ57041.1 - 0.012 15.1 0.6 0.012 15.1 0.6 2.7 2 1 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Spore_coat_CotO PF14153.6 CDJ57042.1 - 7.9 6.4 27.7 0.48 10.3 15.6 2.4 2 0 0 2 2 2 0 Spore coat protein CotO TP53IP5 PF15331.6 CDJ57042.1 - 9.8 6.3 13.9 0.88 9.7 6.7 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 SRP54 PF00448.22 CDJ57043.1 - 1.9e-75 252.8 0.1 4e-75 251.8 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDJ57043.1 - 1.3e-30 106.0 2.7 1.9e-30 105.4 0.3 2.5 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDJ57043.1 - 8.2e-12 45.2 0.4 9.5e-11 41.8 0.2 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CDJ57043.1 - 6.2e-06 26.4 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ57043.1 - 1.3e-05 24.9 0.1 0.00012 21.7 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SR-25 PF10500.9 CDJ57043.1 - 0.00012 21.7 3.2 0.00012 21.7 3.2 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AAA_16 PF13191.6 CDJ57043.1 - 0.00034 21.1 0.1 0.0015 19.0 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 CDJ57043.1 - 0.0015 18.3 0.2 0.0074 16.0 0.0 2.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CDJ57043.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CDJ57043.1 - 0.0021 18.5 0.4 0.014 15.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain DUF4310 PF14187.6 CDJ57043.1 - 0.0028 17.4 0.1 0.005 16.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) DRE2_N PF16803.5 CDJ57043.1 - 0.0033 17.7 0.0 0.44 10.8 0.0 2.6 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus SRPRB PF09439.10 CDJ57043.1 - 0.0039 16.7 2.4 0.64 9.4 0.0 2.9 4 0 0 4 4 4 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CDJ57043.1 - 0.0084 16.4 0.6 0.1 12.8 0.1 3.0 3 1 0 3 3 2 1 AAA domain CbiA PF01656.23 CDJ57043.1 - 0.0088 16.1 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 CDJ57043.1 - 0.01 15.9 0.8 0.17 11.8 0.8 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_24 PF13578.6 CDJ57043.1 - 0.014 16.4 0.0 0.035 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain APS_kinase PF01583.20 CDJ57043.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 CDJ57043.1 - 0.072 12.1 2.6 0.14 11.1 0.0 2.7 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 CDJ57043.1 - 0.1 12.5 0.3 0.51 10.2 0.0 2.4 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 CDJ57043.1 - 0.21 11.7 0.8 1 9.5 0.2 2.4 2 1 0 2 2 1 0 50S ribosome-binding GTPase DpnI_C PF17726.1 CDJ57043.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 Dam-replacing HTH domain UPF0122 PF04297.14 CDJ57043.1 - 0.85 9.9 3.1 2 8.7 0.2 2.6 3 0 0 3 3 2 0 Putative helix-turn-helix protein, YlxM / p13 like STI1 PF17830.1 CDJ57043.1 - 2 8.4 6.5 1.4 8.9 0.8 3.0 2 1 1 3 3 3 0 STI1 domain RAP1 PF07218.11 CDJ57043.1 - 5.5 5.1 5.8 8 4.6 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BSP_II PF05432.11 CDJ57044.1 - 0.0018 18.0 18.0 0.0018 18.0 18.0 4.2 3 1 1 4 4 4 1 Bone sialoprotein II (BSP-II) RskA PF10099.9 CDJ57044.1 - 0.0089 16.3 34.3 0.88 9.8 21.5 4.3 2 1 0 2 2 2 2 Anti-sigma-K factor rskA TFIIF_alpha PF05793.12 CDJ57044.1 - 2.6 6.5 78.6 0.022 13.3 15.6 3.3 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.11 CDJ57045.1 - 0.0033 17.7 23.6 0.0033 17.7 23.6 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Terminase_4 PF05119.12 CDJ57045.1 - 0.97 9.9 7.1 1.2 9.6 4.4 2.3 2 0 0 2 2 2 0 Phage terminase, small subunit SR-25 PF10500.9 CDJ57045.1 - 2.5 7.6 39.7 0.19 11.3 23.5 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SARAF PF06682.12 CDJ57045.1 - 2.8 7.5 12.3 1.6 8.3 7.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CPSF100_C PF13299.6 CDJ57045.1 - 3.6 7.7 11.7 2.5 8.2 2.6 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AP3D1 PF06375.11 CDJ57045.1 - 3.6 7.8 20.7 0.44 10.8 12.0 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF3807 PF12720.7 CDJ57045.1 - 8.7 6.6 14.1 3.6 7.8 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Lin-8 PF03353.15 CDJ57045.1 - 10 5.6 14.1 0.38 10.3 1.6 2.6 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ57047.1 - 6.8e-05 22.0 5.0 6.8e-05 22.0 5.0 11.6 11 1 1 12 12 12 1 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ57047.1 - 0.00059 18.9 2.4 0.00059 18.9 2.4 11.1 7 3 2 11 11 11 2 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ57047.1 - 0.0017 18.4 14.2 0.0017 18.4 14.2 8.2 4 1 3 7 7 7 3 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 CDJ57048.1 - 1.4e-21 76.9 0.3 6.9e-21 74.7 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDJ57048.1 - 1.1e-10 41.6 0.2 1.7e-08 34.5 0.1 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDJ57048.1 - 4.2e-05 23.6 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDJ57048.1 - 0.0098 16.0 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family PduV-EutP PF10662.9 CDJ57048.1 - 0.065 13.0 0.1 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ECR1_N PF14382.6 CDJ57050.1 - 2.4e-09 36.8 0.2 4.4e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Memo PF01875.17 CDJ57051.1 - 7.8e-29 100.7 0.0 4.5e-28 98.2 0.0 1.8 1 1 0 1 1 1 1 Memo-like protein cNMP_binding PF00027.29 CDJ57052.1 - 2.4e-29 101.2 0.1 9.1e-22 76.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RP-C_C PF11800.8 CDJ57052.1 - 0.0026 17.9 9.9 0.0039 17.3 9.9 1.2 1 0 0 1 1 1 1 Replication protein C C-terminal region TFIIA PF03153.13 CDJ57052.1 - 0.006 16.6 18.4 0.0078 16.3 18.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ57052.1 - 0.038 14.1 1.8 0.051 13.7 1.8 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ57052.1 - 0.083 11.6 12.9 0.12 11.2 12.9 1.2 1 0 0 1 1 1 0 Presenilin Myc_N PF01056.18 CDJ57052.1 - 0.091 12.6 7.8 0.17 11.8 7.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Na_trans_assoc PF06512.13 CDJ57052.1 - 0.12 12.6 11.7 0.3 11.4 11.7 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 CDJ57052.1 - 0.13 11.9 18.2 0.26 11.0 18.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 CDJ57052.1 - 0.26 11.2 15.3 0.4 10.6 15.3 1.2 1 0 0 1 1 1 0 SPX domain Totivirus_coat PF05518.11 CDJ57052.1 - 0.63 8.0 4.9 0.88 7.5 4.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein Glypican PF01153.19 CDJ57052.1 - 0.64 8.8 11.8 0.91 8.3 11.8 1.1 1 0 0 1 1 1 0 Glypican V_ATPase_I PF01496.19 CDJ57052.1 - 0.79 7.6 6.9 1 7.2 6.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 CDJ57052.1 - 2.4 8.1 6.9 3.5 7.6 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NOA36 PF06524.12 CDJ57052.1 - 3 7.1 14.3 4.5 6.5 14.3 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_S64 PF08192.11 CDJ57052.1 - 4 5.8 9.7 5.2 5.4 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 RPN2_C PF18004.1 CDJ57052.1 - 4.8 7.1 12.3 10 6.0 12.3 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 CDJ57052.1 - 5.3 6.1 7.1 7 5.8 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 CDJ57052.1 - 8.5 6.6 23.7 33 4.7 23.8 1.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR PPP4R2 PF09184.11 CDJ57052.1 - 9.8 5.7 17.4 16 5.0 17.4 1.2 1 0 0 1 1 1 0 PPP4R2 RskA PF10099.9 CDJ57053.1 - 1.4e-06 28.7 102.3 0.0011 19.3 15.5 6.1 1 1 3 5 5 5 3 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.18 CDJ57053.1 - 0.00055 19.7 0.0 0.31 10.7 0.0 3.3 2 1 0 2 2 2 1 DNA methylase DUF2722 PF10846.8 CDJ57053.1 - 0.0033 16.5 13.1 0.0033 16.5 13.1 6.2 4 2 1 5 5 5 1 Protein of unknown function (DUF2722) Dehydrin PF00257.19 CDJ57053.1 - 0.044 14.3 0.4 0.044 14.3 0.4 6.9 6 2 0 7 7 7 0 Dehydrin DUF3446 PF11928.8 CDJ57054.1 - 3.3e-05 24.1 7.6 0.034 14.5 0.5 2.6 2 0 0 2 2 2 2 Early growth response N-terminal domain SR-25 PF10500.9 CDJ57054.1 - 0.0007 19.3 15.1 0.0044 16.7 6.0 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Nmad2 PF18753.1 CDJ57054.1 - 0.74 9.2 5.5 1.3 8.5 5.5 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 CdiA_C PF18451.1 CDJ57054.1 - 0.96 9.7 3.7 0.63 10.3 0.1 2.2 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain P5-ATPase PF12409.8 CDJ57054.1 - 5.4 7.1 5.8 14 5.8 3.9 2.2 2 0 0 2 2 2 0 P5-type ATPase cation transporter Spt20 PF12090.8 CDJ57054.1 - 7 6.2 35.5 0.75 9.4 22.0 2.6 2 0 0 2 2 2 0 Spt20 family IBN_N PF03810.19 CDJ57055.1 - 1.1e-09 38.0 0.0 6.9e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Chloroplast_duf PF14476.6 CDJ57055.1 - 0.036 13.0 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Petal formation-expressed MOFRL PF05161.13 CDJ57055.1 - 0.82 9.9 3.1 3.5 7.9 0.1 3.2 3 1 1 4 4 4 0 MOFRL family Ribosomal_60s PF00428.19 CDJ57055.1 - 7.3 7.3 11.1 2.1 9.0 0.6 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein NFACT-R_1 PF05670.13 CDJ57056.1 - 3e-28 98.6 5.9 8.6e-17 61.8 0.0 4.6 4 0 0 4 4 4 2 NFACT protein RNA binding domain FbpA PF05833.11 CDJ57056.1 - 2.2e-12 46.5 1.6 2.2e-12 46.5 1.6 11.5 8 3 2 10 10 10 2 Fibronectin-binding protein A N-terminus (FbpA) Sin_N PF04801.13 CDJ57056.1 - 0.00025 20.4 22.5 0.00025 20.4 22.5 11.2 5 5 2 9 9 9 1 Sin-like protein conserved region RskA PF10099.9 CDJ57056.1 - 0.00069 20.0 3.3 0.00069 20.0 3.3 17.2 4 3 11 16 16 16 6 Anti-sigma-K factor rskA PAP1 PF08601.10 CDJ57056.1 - 1.3 8.7 0.0 1.3 8.7 0.0 9.6 6 2 2 8 8 8 0 Transcription factor PAP1 HAT PF02184.16 CDJ57058.1 - 0.002 18.0 0.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CDJ57058.1 - 0.0025 18.5 1.7 0.2 12.6 0.1 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat PMI_typeI PF01238.21 CDJ57058.1 - 0.029 13.6 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I AP2 PF00847.20 CDJ57059.1 - 9e-09 35.4 1.8 1.5e-07 31.5 1.1 3.2 2 0 0 2 2 2 1 AP2 domain SUIM_assoc PF16619.5 CDJ57059.1 - 0.0061 16.6 1.9 0.0061 16.6 1.9 11.6 7 4 1 8 8 8 1 Unstructured region C-term to UIM in Ataxin3 PAN_1 PF00024.26 CDJ57062.1 - 4.1e-46 154.8 80.7 3.9e-07 29.9 5.9 10.4 5 4 4 10 10 10 10 PAN domain PAN_4 PF14295.6 CDJ57062.1 - 4.4e-33 113.0 73.5 1.2e-05 25.1 1.5 11.2 10 1 0 10 10 10 9 PAN domain PAN_2 PF08276.11 CDJ57062.1 - 6.8e-06 26.1 74.8 0.0033 17.5 5.0 10.1 10 0 0 10 10 10 6 PAN-like domain PAN_3 PF08277.12 CDJ57062.1 - 0.046 13.5 0.2 0.046 13.5 0.2 9.2 10 0 0 10 10 10 0 PAN-like domain PAN_1 PF00024.26 CDJ57063.1 - 1.6e-65 217.0 89.0 1.8e-08 34.2 4.6 11.4 7 4 4 11 11 11 11 PAN domain PAN_4 PF14295.6 CDJ57063.1 - 3.5e-41 138.9 83.8 3.7e-07 29.9 0.7 12.6 11 3 0 11 11 11 10 PAN domain PAN_2 PF08276.11 CDJ57063.1 - 7.7e-15 54.8 77.7 0.0029 17.7 0.5 11.2 11 0 0 11 11 11 9 PAN-like domain PAN_3 PF08277.12 CDJ57063.1 - 0.0038 17.0 0.8 0.0038 17.0 0.8 10.4 11 0 0 11 11 11 6 PAN-like domain Ras PF00071.22 CDJ57066.1 - 8.6e-44 149.0 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ57066.1 - 4.9e-28 97.8 0.0 9.7e-28 96.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ57066.1 - 6.4e-10 38.8 0.1 8.6e-10 38.3 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ57066.1 - 0.00058 19.9 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ57066.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 CDJ57066.1 - 0.0056 16.6 1.2 0.14 12.1 0.2 2.2 2 0 0 2 2 2 1 NTPase ArgoMid PF16487.5 CDJ57066.1 - 0.014 15.6 0.1 0.032 14.5 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 CDJ57066.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CDJ57066.1 - 0.036 14.5 0.2 0.42 11.0 0.2 2.4 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 CDJ57066.1 - 0.045 12.9 0.0 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 CDJ57066.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CDJ57066.1 - 0.09 12.0 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 CDJ57066.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 CDJ57066.1 - 0.12 12.4 0.3 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ57066.1 - 0.16 12.1 1.3 0.4 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain Mad3_BUB1_I PF08311.12 CDJ57067.1 - 1.7e-06 28.0 6.3 0.23 11.5 0.4 5.2 5 2 0 5 5 5 2 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 CDJ57067.1 - 2.2e-05 24.9 30.7 1.2 10.2 0.6 10.5 8 4 5 13 13 13 3 Tetratricopeptide repeat RPN7 PF10602.9 CDJ57067.1 - 4.6e-05 23.2 1.4 0.4 10.4 0.1 4.1 2 1 0 3 3 3 2 26S proteasome subunit RPN7 TPR_2 PF07719.17 CDJ57067.1 - 0.0092 16.0 20.3 32 5.0 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat PPR PF01535.20 CDJ57067.1 - 0.33 11.3 3.1 20 5.7 0.0 4.5 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.6 CDJ57067.1 - 2.2 8.7 15.8 17 5.9 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ57067.1 - 7.7 6.1 15.6 0.064 12.9 6.2 2.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Mis12 PF05859.12 CDJ57067.1 - 8 6.5 9.6 0.41 10.7 1.3 2.5 2 0 0 2 2 2 0 Mis12 protein 7TM_GPCR_Srh PF10318.9 CDJ57068.1 - 0.019 14.0 2.9 0.025 13.6 2.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh MARVEL PF01284.23 CDJ57068.1 - 0.2 11.7 9.0 0.24 11.4 9.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF4134 PF13572.6 CDJ57068.1 - 0.83 10.0 6.6 0.15 12.3 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4134) zf-CCHC PF00098.23 CDJ57071.1 - 2.4e-06 27.4 0.7 5e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIA PF03153.13 CDJ57071.1 - 7.3e-06 26.2 79.6 0.00013 22.1 33.6 3.0 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ57071.1 - 0.002 17.8 4.6 0.002 17.8 4.6 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Surp PF01805.20 CDJ57071.1 - 0.0085 16.1 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Surp module zf-CCHC_5 PF14787.6 CDJ57071.1 - 0.032 14.0 1.6 0.082 12.6 1.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CDJ57071.1 - 5.1 6.9 5.8 0.49 10.2 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle DDHD PF02862.17 CDJ57071.1 - 6.9 6.8 19.6 7.2 6.7 6.1 3.2 3 0 0 3 3 3 0 DDHD domain Spt20 PF12090.8 CDJ57072.1 - 6.8 6.2 17.1 9.8 5.7 16.7 1.4 2 0 0 2 2 2 0 Spt20 family Acetyltransf_1 PF00583.25 CDJ57073.1 - 4.9e-06 26.8 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RNA_pol_3_Rpc31 PF11705.8 CDJ57073.1 - 0.0096 16.2 2.1 0.0096 16.2 2.1 3.5 4 1 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 Acetyltransf_7 PF13508.7 CDJ57073.1 - 0.01 16.2 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CDJ57073.1 - 0.088 12.3 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase DUF4179 PF13786.6 CDJ57073.1 - 0.14 12.7 0.2 0.14 12.7 0.2 6.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4179) DUF2722 PF10846.8 CDJ57073.1 - 1.5 7.7 37.8 1.3 7.8 2.5 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2722) DUF4471 PF14740.6 CDJ57073.1 - 1.6 7.9 5.7 6.4 5.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Vfa1 PF08432.10 CDJ57073.1 - 2.2 8.6 36.8 0.059 13.7 9.4 3.2 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 PIP5K PF01504.18 CDJ57073.1 - 2.5 7.2 9.7 0.97 8.6 0.5 2.9 3 0 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase Plasmodium_Vir PF05795.11 CDJ57073.1 - 3.2 7.1 12.9 1.4 8.3 3.2 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein GIDA PF01134.22 CDJ57074.1 - 1e-72 245.5 19.2 2.5e-42 145.4 2.0 4.5 3 1 1 4 4 4 3 Glucose inhibited division protein A GIDA_assoc PF13932.6 CDJ57074.1 - 5.2e-07 30.1 0.1 5.2e-07 30.1 0.1 4.2 4 0 0 4 4 4 1 GidA associated domain Pyr_redox_2 PF07992.14 CDJ57074.1 - 0.0019 17.5 7.7 0.0053 16.0 4.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2722 PF10846.8 CDJ57074.1 - 0.97 8.3 0.0 0.051 12.5 4.6 6.8 4 1 3 7 7 7 0 Protein of unknown function (DUF2722) Cytochrom_C PF00034.21 CDJ57075.1 - 8.8e-12 46.0 0.0 1.1e-11 45.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ57075.1 - 1.6e-06 28.3 2.1 4.2e-06 27.0 2.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ57075.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain PC_rep PF01851.22 CDJ57078.1 - 0.017 15.6 0.6 0.026 15.0 0.6 1.3 1 0 0 1 1 1 0 Proteasome/cyclosome repeat TFIIA PF03153.13 CDJ57079.1 - 0.032 14.3 32.0 0.036 14.1 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4710 PF15828.5 CDJ57079.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) ADP_ribosyl_GH PF03747.14 CDJ57079.1 - 0.66 9.7 18.2 0.89 9.2 17.3 1.6 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase LCD1 PF09798.9 CDJ57079.1 - 2 6.9 13.1 2.5 6.5 13.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Vfa1 PF08432.10 CDJ57079.1 - 6.2 7.1 26.8 3.6 7.9 8.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SUIM_assoc PF16619.5 CDJ57080.1 - 5.5e-05 23.2 0.6 5.5e-05 23.2 0.6 1.3 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF410 PF04190.13 CDJ57080.1 - 0.043 13.6 2.6 0.064 13.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF410) PKI PF02827.16 CDJ57080.1 - 0.09 13.0 2.2 0.15 12.3 2.2 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor SpoIIE PF07228.12 CDJ57081.1 - 5.9e-06 26.3 2.7 7.3e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) DUF2722 PF10846.8 CDJ57081.1 - 0.00046 19.3 1.2 0.00061 18.9 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ57081.1 - 0.014 15.4 10.8 0.014 15.4 10.8 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ57081.1 - 0.045 13.4 12.7 0.061 12.9 12.7 1.2 1 0 0 1 1 1 0 Spt20 family PP2C PF00481.21 CDJ57081.1 - 0.061 12.9 0.2 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C RskA PF10099.9 CDJ57081.1 - 0.11 12.8 13.9 0.19 12.0 11.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PP2C_2 PF13672.6 CDJ57081.1 - 0.51 9.9 13.2 3.5 7.2 0.0 3.1 2 1 1 3 3 3 0 Protein phosphatase 2C DivIC PF04977.15 CDJ57081.1 - 3.8 7.3 11.6 7.8 6.3 11.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Activator_LAG-3 PF11498.8 CDJ57081.1 - 3.9 6.3 23.1 5.3 5.9 23.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HEAT PF02985.22 CDJ57082.1 - 0.00013 21.9 2.7 2.5 8.6 0.1 4.5 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CDJ57082.1 - 0.00069 19.7 0.5 0.0022 18.0 0.5 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDJ57082.1 - 0.0023 18.4 2.7 0.0023 18.4 2.7 7.4 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 CDJ57082.1 - 0.0051 17.2 22.9 0.36 11.2 0.5 5.5 4 1 2 6 6 6 3 HEAT repeats Arm PF00514.23 CDJ57082.1 - 0.036 14.1 7.0 0.34 11.0 0.6 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2722 PF10846.8 CDJ57082.1 - 0.33 9.8 16.7 0.081 11.9 13.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CSG2 PF16965.5 CDJ57082.1 - 0.37 9.7 2.0 0.61 9.0 2.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator DUF3446 PF11928.8 CDJ57082.1 - 1.7 9.0 8.9 6.9 7.0 3.3 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain HrcA PF01628.21 CDJ57082.1 - 5.7 6.8 9.0 7.5 6.4 6.1 2.3 1 1 1 2 2 2 0 HrcA protein C terminal domain RSRP PF17069.5 CDJ57083.1 - 3.1 7.3 53.6 5.3 6.5 53.6 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 CDJ57083.1 - 7.9 4.6 16.7 12 4.0 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4131 PF13567.6 CDJ57084.1 - 0.0004 20.1 0.1 0.00059 19.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) SR-25 PF10500.9 CDJ57084.1 - 0.00041 20.1 14.7 0.00059 19.5 14.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PA26 PF04636.13 CDJ57084.1 - 0.013 14.5 4.4 0.013 14.4 4.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RskA PF10099.9 CDJ57084.1 - 0.017 15.4 6.2 0.024 14.9 6.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Tmemb_9 PF05434.11 CDJ57084.1 - 0.018 14.9 4.4 0.026 14.4 4.4 1.4 1 0 0 1 1 1 0 TMEM9 Suf PF05843.14 CDJ57084.1 - 0.024 14.6 10.2 0.03 14.3 10.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ57084.1 - 0.085 13.0 7.2 0.1 12.8 7.2 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ57084.1 - 0.11 12.5 6.3 0.13 12.3 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ57084.1 - 0.11 11.4 3.0 0.13 11.1 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SMYLE_N PF18615.1 CDJ57084.1 - 0.13 11.8 10.5 0.16 11.5 10.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CSG2 PF16965.5 CDJ57084.1 - 0.17 10.8 2.8 0.17 10.8 2.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator EOS1 PF12326.8 CDJ57084.1 - 0.22 11.5 3.7 0.26 11.2 3.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein TCP PF03634.13 CDJ57084.1 - 0.3 11.6 16.3 0.44 11.1 16.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor CCDC106 PF15794.5 CDJ57084.1 - 0.37 10.5 14.2 0.54 9.9 14.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Transposase_21 PF02992.14 CDJ57084.1 - 0.49 9.6 2.1 0.65 9.2 2.1 1.1 1 0 0 1 1 1 0 Transposase family tnp2 IMUP PF15761.5 CDJ57084.1 - 0.98 10.1 12.6 0.14 12.8 8.6 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein CLN3 PF02487.17 CDJ57084.1 - 1.4 7.9 4.2 1.5 7.7 4.2 1.1 1 0 0 1 1 1 0 CLN3 protein MMR1 PF08505.10 CDJ57084.1 - 1.4 9.2 18.6 2.1 8.6 18.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Connexin PF00029.19 CDJ57084.1 - 2.2 8.0 6.1 3 7.6 6.1 1.3 1 0 0 1 1 1 0 Connexin PalH PF08733.10 CDJ57084.1 - 3.4 6.6 6.2 0.16 10.9 0.1 1.7 1 1 1 2 2 2 0 PalH/RIM21 Coilin_N PF15862.5 CDJ57084.1 - 3.8 7.3 17.3 6.1 6.6 17.3 1.4 1 0 0 1 1 1 0 Coilin N-terminus FAM199X PF15814.5 CDJ57084.1 - 4.9 6.1 15.6 6.8 5.7 15.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X PT PF04886.12 CDJ57085.1 - 0.00016 21.2 3.6 0.00016 21.2 3.6 3.9 2 1 1 3 3 3 2 PT repeat Wzy_C PF04932.15 CDJ57085.1 - 0.025 14.2 0.0 17 5.0 3.7 2.2 1 1 1 2 2 2 0 O-Antigen ligase Shisa PF13908.6 CDJ57085.1 - 0.1 12.8 0.4 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4179 PF13786.6 CDJ57085.1 - 2.2 8.8 0.0 2.2 8.8 0.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4179) Pinin_SDK_memA PF04696.13 CDJ57086.1 - 0.17 12.0 24.6 0.2 11.7 24.6 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4207 PF13904.6 CDJ57086.1 - 0.17 11.5 25.9 0.28 10.8 25.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Velvet PF11754.8 CDJ57086.1 - 0.33 10.9 9.8 0.35 10.8 9.8 1.1 1 0 0 1 1 1 0 Velvet factor RskA PF10099.9 CDJ57086.1 - 0.67 10.2 12.8 0.97 9.7 12.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CENP-U PF13097.6 CDJ57086.1 - 0.78 9.7 20.0 0.98 9.3 20.0 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF4569 PF15133.6 CDJ57086.1 - 1.3 8.7 16.3 1.4 8.6 16.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Plexin_cytopl PF08337.12 CDJ57086.1 - 1.6 7.3 12.6 1.9 7.1 12.6 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain BORG_CEP PF14957.6 CDJ57086.1 - 1.6 9.9 7.9 2.1 9.5 7.9 1.1 1 0 0 1 1 1 0 Cdc42 effector Suf PF05843.14 CDJ57086.1 - 1.9 8.4 17.2 2.4 8.0 17.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ57086.1 - 3.1 6.5 18.1 3.4 6.3 18.1 1.0 1 0 0 1 1 1 0 Presenilin Sin_N PF04801.13 CDJ57086.1 - 3.3 6.8 26.6 3.7 6.6 26.6 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Otopetrin PF03189.13 CDJ57086.1 - 3.3 6.4 6.8 4.9 5.9 6.8 1.3 1 0 0 1 1 1 0 Otopetrin PPP4R2 PF09184.11 CDJ57086.1 - 3.3 7.2 10.2 4.1 6.9 10.2 1.1 1 0 0 1 1 1 0 PPP4R2 CAML PF14963.6 CDJ57086.1 - 4.4 7.3 8.1 5.2 7.1 8.1 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand BAT2_N PF07001.11 CDJ57086.1 - 5.6 7.4 22.1 6.8 7.1 22.1 1.0 1 0 0 1 1 1 0 BAT2 N-terminus DUF2052 PF09747.9 CDJ57086.1 - 6.6 6.8 19.1 8 6.5 19.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDRGK PF09756.9 CDJ57086.1 - 7.6 6.1 22.9 10 5.7 22.9 1.2 1 0 0 1 1 1 0 DDRGK domain Raftlin PF15250.6 CDJ57086.1 - 7.7 5.1 13.8 9.1 4.9 13.8 1.0 1 0 0 1 1 1 0 Raftlin Calici_coat PF00915.20 CDJ57086.1 - 9.3 5.0 7.7 11 4.8 7.7 1.0 1 0 0 1 1 1 0 Calicivirus coat protein RskA PF10099.9 CDJ57087.1 - 1.2e-05 25.7 7.0 1.2e-05 25.7 7.0 22.1 8 6 8 16 16 16 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ57087.1 - 0.0021 17.1 5.1 0.0021 17.1 5.1 12.9 11 2 1 13 13 13 3 Protein of unknown function (DUF2722) EphA2_TM PF14575.6 CDJ57088.1 - 0.12 13.3 33.4 1.1 10.2 0.5 6.7 6 0 0 6 6 6 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.9 CDJ57090.1 - 0.00019 21.8 4.1 0.00019 21.8 4.1 12.9 4 3 1 8 8 8 2 Anti-sigma-K factor rskA Nudix_hydro PF18290.1 CDJ57091.1 - 0.0058 16.6 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 Nudix hydrolase domain RskA PF10099.9 CDJ57093.1 - 0.0041 17.4 20.6 0.0041 17.4 20.6 7.2 1 1 4 5 5 5 1 Anti-sigma-K factor rskA MMR1 PF08505.10 CDJ57093.1 - 1.8 8.8 44.0 1 9.6 1.0 4.2 3 1 0 4 4 4 0 Mitochondrial Myo2 receptor-related protein DUF2722 PF10846.8 CDJ57093.1 - 3.7 6.4 62.5 0.31 9.9 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Ribosomal_S9 PF00380.19 CDJ57094.1 - 1.6e-18 67.3 0.1 2.1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF913 PF06025.12 CDJ57094.1 - 0.0066 15.5 2.4 0.0054 15.8 2.4 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 CDJ57094.1 - 0.018 15.5 5.5 0.019 15.4 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 CDJ57094.1 - 0.041 13.7 5.4 0.048 13.5 5.4 1.2 1 0 0 1 1 1 0 Coilin N-terminus Paf1 PF03985.13 CDJ57094.1 - 0.044 12.8 31.2 0.051 12.6 31.2 1.1 1 0 0 1 1 1 0 Paf1 DDHD PF02862.17 CDJ57094.1 - 0.075 13.2 2.1 0.083 13.0 2.1 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 CDJ57094.1 - 0.11 11.2 5.3 0.11 11.2 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 CDJ57094.1 - 0.3 10.8 6.5 0.29 10.9 6.5 1.1 1 0 0 1 1 1 0 AAA domain SspB PF04386.13 CDJ57094.1 - 0.31 10.9 11.2 0.42 10.5 11.2 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Peptidase_C37 PF05416.12 CDJ57094.1 - 0.34 9.4 5.8 0.32 9.5 5.8 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase PIP5K PF01504.18 CDJ57094.1 - 0.47 9.6 3.9 0.51 9.5 3.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase PPL5 PF18168.1 CDJ57094.1 - 0.76 9.0 8.0 0.91 8.8 8.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SID-1_RNA_chan PF13965.6 CDJ57094.1 - 0.82 8.0 1.6 0.86 7.9 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ57094.1 - 1.2 8.0 3.8 1.4 7.8 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mpp10 PF04006.12 CDJ57094.1 - 1.3 7.3 33.1 1.5 7.1 33.1 1.0 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 CDJ57094.1 - 1.4 8.2 27.7 1.6 8.0 27.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CDJ57094.1 - 2 6.5 33.6 2.3 6.3 33.6 1.0 1 0 0 1 1 1 0 Nop14-like family RP-C_C PF11800.8 CDJ57094.1 - 2.1 8.4 14.7 29 4.7 0.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region TERB2 PF15101.6 CDJ57094.1 - 2.9 7.9 8.8 3.7 7.6 8.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CLN3 PF02487.17 CDJ57094.1 - 3.1 6.7 5.5 3.5 6.6 5.5 1.1 1 0 0 1 1 1 0 CLN3 protein RRN3 PF05327.11 CDJ57094.1 - 3.9 5.9 16.3 4 5.9 16.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Connexin PF00029.19 CDJ57094.1 - 4.3 7.0 15.3 5.8 6.6 15.3 1.1 1 0 0 1 1 1 0 Connexin CobT PF06213.12 CDJ57094.1 - 4.5 6.6 34.6 5.4 6.3 34.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 CDJ57094.1 - 7.3 4.8 29.3 8.6 4.5 29.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ57094.1 - 8 5.4 7.8 9 5.2 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RAB3GAP2_C PF14656.6 CDJ57094.1 - 9.2 4.4 9.0 12 3.9 9.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus GNAT_acetyltr_2 PF13718.6 CDJ57094.1 - 9.8 5.5 7.8 15 4.9 7.8 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4301 PF14134.6 CDJ57095.1 - 0.39 9.5 0.4 0.58 8.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) SUIM_assoc PF16619.5 CDJ57095.1 - 1.4 9.1 14.0 0.026 14.6 1.9 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ57095.1 - 3.8 7.0 9.6 0.25 11.0 3.2 2.1 3 0 0 3 3 3 0 Spt20 family DUF5470 PF17564.2 CDJ57095.1 - 5 7.4 5.9 10 6.4 5.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) CCDC-167 PF15188.6 CDJ57095.1 - 7.1 7.1 6.7 6.5 7.2 0.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 IMUP PF15761.5 CDJ57095.1 - 8.4 7.1 18.7 0.12 13.0 5.7 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein RRM_1 PF00076.22 CDJ57096.1 - 1.8e-16 59.7 0.0 3.4e-15 55.6 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ57096.1 - 8e-10 38.7 0.0 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Apt1 PF10351.9 CDJ57096.1 - 4.3e-05 22.6 12.9 5.2e-05 22.3 12.9 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ57096.1 - 0.0095 14.5 23.9 0.017 13.8 23.9 1.3 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 CDJ57096.1 - 0.046 13.6 22.1 0.065 13.2 22.1 1.2 1 0 0 1 1 1 0 SPX domain RskA PF10099.9 CDJ57096.1 - 0.061 13.6 0.1 0.061 13.6 0.1 3.9 3 1 0 3 3 2 0 Anti-sigma-K factor rskA Pkinase_fungal PF17667.1 CDJ57096.1 - 1.8 7.3 4.3 2.5 6.8 4.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nop14 PF04147.12 CDJ57096.1 - 1.9 6.6 6.1 2.3 6.3 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family QWRF PF04484.12 CDJ57096.1 - 3.4 7.3 19.5 5 6.8 19.5 1.3 1 0 0 1 1 1 0 QWRF family Paf1 PF03985.13 CDJ57096.1 - 5.2 6.0 8.5 7.3 5.5 8.5 1.2 1 0 0 1 1 1 0 Paf1 Raftlin PF15250.6 CDJ57096.1 - 10 4.8 12.7 14 4.3 12.7 1.1 1 0 0 1 1 1 0 Raftlin MAP65_ASE1 PF03999.12 CDJ57098.1 - 0.0012 17.6 5.2 0.0012 17.6 5.2 9.8 7 2 1 9 9 9 1 Microtubule associated protein (MAP65/ASE1 family) RskA PF10099.9 CDJ57098.1 - 0.0062 16.9 3.2 0.0062 16.9 3.2 15.2 6 4 6 12 12 12 6 Anti-sigma-K factor rskA Yip1 PF04893.17 CDJ57098.1 - 0.83 9.3 6.5 0.056 13.2 0.3 2.2 2 0 0 2 2 2 0 Yip1 domain DAO PF01266.24 CDJ57099.1 - 3.8e-18 66.2 0.1 9e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ57099.1 - 0.002 17.4 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ57099.1 - 0.0029 16.7 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDJ57099.1 - 0.0039 16.6 0.2 0.0056 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDJ57099.1 - 0.052 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CDJ57099.1 - 0.085 11.5 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CDJ57099.1 - 0.086 11.9 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDJ57099.1 - 0.15 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Aminotran_1_2 PF00155.21 CDJ57100.1 - 7.4e-29 101.0 0.0 2.3e-28 99.4 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Gram_pos_anchor PF00746.21 CDJ57100.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif IP_trans PF02121.18 CDJ57101.1 - 2.2e-62 210.8 0.0 2.2e-43 148.6 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.18 CDJ57101.1 - 1.2e-15 57.2 0.0 3.9e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Oxysterol-binding protein PH PF00169.29 CDJ57101.1 - 6.4e-15 55.6 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDJ57101.1 - 0.0028 18.1 0.1 0.026 14.9 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CDJ57101.1 - 0.14 12.5 0.3 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Kinesin PF00225.23 CDJ57102.1 - 1.3e-73 247.8 0.0 1.3e-73 247.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ57102.1 - 1.2e-07 31.8 0.0 2.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding CDK2AP PF09806.9 CDJ57102.1 - 0.0018 18.4 8.6 0.0029 17.7 8.6 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Secretin_N_2 PF07655.13 CDJ57102.1 - 0.013 16.0 15.1 0.039 14.5 15.1 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain CCDC24 PF15669.5 CDJ57102.1 - 0.14 12.1 2.8 0.22 11.4 2.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 CDJ57102.1 - 0.45 10.1 13.8 0.91 9.1 13.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 CDJ57102.1 - 1.7 7.6 7.5 2.9 6.8 7.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FSA_C PF10479.9 CDJ57102.1 - 3 5.9 14.4 4.9 5.2 14.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Spt20 PF12090.8 CDJ57103.1 - 3.1e-05 23.7 11.2 3.1e-05 23.7 11.2 4.7 3 1 1 4 4 4 2 Spt20 family Consortin_C PF15281.6 CDJ57103.1 - 2.2 8.3 3.4 54 3.8 0.1 3.2 1 1 1 2 2 2 0 Consortin C-terminus Amidinotransf PF02274.17 CDJ57104.1 - 0.21 10.6 0.4 0.36 9.9 0.4 1.3 1 0 0 1 1 1 0 Amidinotransferase IFN-gamma PF00714.17 CDJ57105.1 - 0.082 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Interferon gamma T3SchapCesA PF11439.8 CDJ57105.1 - 0.98 9.6 3.5 0.89 9.7 1.2 2.2 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA TMEM51 PF15345.6 CDJ57107.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 PTPRCAP PF15713.5 CDJ57107.1 - 0.065 13.5 0.5 0.065 13.5 0.5 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 CDJ57107.1 - 0.072 11.8 12.2 0.077 11.8 12.2 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ57107.1 - 0.31 10.8 8.6 2.3 8.0 0.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ57107.1 - 0.5 8.6 15.4 3.5 5.8 15.4 1.9 1 1 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CDJ57107.1 - 1.3 9.0 9.4 1.6 8.7 9.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 CDJ57107.1 - 2.1 8.7 8.0 1.3 9.4 1.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Renin_r PF07850.14 CDJ57107.1 - 2.6 8.7 10.0 2.9 8.5 2.1 2.0 2 0 0 2 2 2 0 Renin receptor-like protein DUF2232 PF09991.9 CDJ57109.1 - 0.031 13.5 0.2 0.031 13.5 0.2 3.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2232) Sec23_trunk PF04811.15 CDJ57109.1 - 1.3 8.5 13.5 2.2 7.8 3.2 2.9 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Med15 PF09606.10 CDJ57110.1 - 0.0038 16.0 13.8 0.0038 16.0 13.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ57110.1 - 0.0054 17.0 4.8 0.0066 16.8 4.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Roughex PF06020.11 CDJ57110.1 - 0.0061 15.7 4.4 0.0061 15.7 4.4 1.2 1 0 0 1 1 1 1 Drosophila roughex protein Activator_LAG-3 PF11498.8 CDJ57110.1 - 0.0071 15.4 19.2 0.0079 15.2 19.2 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 baeRF_family10 PF18854.1 CDJ57110.1 - 0.03 14.6 2.5 0.038 14.2 2.5 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 TFIIA PF03153.13 CDJ57110.1 - 0.064 13.2 21.3 0.068 13.2 21.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ57110.1 - 0.069 12.5 6.3 0.075 12.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 CDJ57110.1 - 0.15 12.0 9.8 0.18 11.7 9.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LCD1 PF09798.9 CDJ57110.1 - 0.24 9.9 6.2 0.26 9.8 6.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein USP8_interact PF08941.10 CDJ57110.1 - 0.26 11.1 8.2 0.36 10.6 8.2 1.2 1 0 0 1 1 1 0 USP8 interacting Cytomega_TRL10 PF06084.11 CDJ57110.1 - 2.2 8.3 7.4 0.18 11.8 2.4 1.7 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Presenilin PF01080.17 CDJ57110.1 - 3.8 6.2 10.6 4.6 5.9 10.6 1.3 1 0 0 1 1 1 0 Presenilin DUF1676 PF07898.13 CDJ57110.1 - 3.8 7.5 6.1 4.7 7.2 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Neur_chan_memb PF02932.16 CDJ57110.1 - 4.1 7.4 10.7 4.8 7.2 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Itfg2 PF15907.5 CDJ57111.1 - 0.0055 15.8 3.2 0.0065 15.6 3.2 1.1 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 EIF4E-T PF10477.9 CDJ57111.1 - 0.013 14.3 10.0 0.014 14.2 10.0 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TFIIA PF03153.13 CDJ57111.1 - 0.029 14.4 27.6 0.035 14.1 27.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ57111.1 - 0.034 14.4 21.5 0.056 13.7 21.5 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FAM60A PF15396.6 CDJ57111.1 - 0.044 13.8 1.4 0.048 13.7 1.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Activator_LAG-3 PF11498.8 CDJ57111.1 - 0.056 12.4 29.2 0.066 12.2 29.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 CDJ57111.1 - 0.12 12.4 4.7 0.13 12.3 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2890 PF11081.8 CDJ57111.1 - 0.12 12.5 7.9 0.16 12.0 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BPL_N PF09825.9 CDJ57111.1 - 0.15 11.1 3.5 0.17 10.9 3.5 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Peptidase_S15 PF02129.18 CDJ57111.1 - 0.19 11.3 10.4 0.25 10.9 10.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CLN3 PF02487.17 CDJ57111.1 - 0.29 10.1 3.3 0.32 10.0 3.3 1.1 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ57111.1 - 0.47 9.2 4.7 0.46 9.2 4.7 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ57111.1 - 0.48 8.6 18.1 0.52 8.5 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TALPID3 PF15324.6 CDJ57111.1 - 0.52 7.9 19.4 0.61 7.7 19.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Pannexin_like PF12534.8 CDJ57111.1 - 1.3 8.0 10.5 1.7 7.6 10.5 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 TraT PF05818.12 CDJ57111.1 - 6.3 6.4 9.9 17 5.1 9.9 1.8 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein FoP_duplication PF13865.6 CDJ57112.1 - 1.2e-12 48.2 36.7 6.4e-10 39.5 32.0 3.2 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 SUIM_assoc PF16619.5 CDJ57112.1 - 0.00081 19.4 10.1 0.64 10.1 8.1 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 CDJ57112.1 - 2.6 6.9 5.5 2.6 6.9 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ala_racemase_N PF01168.20 CDJ57113.1 - 2.4e-08 33.9 0.8 2.4e-08 33.9 0.8 2.2 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain GCOM2 PF15328.6 CDJ57113.1 - 0.67 10.3 7.2 0.4 11.0 0.4 2.1 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Porin_5 PF16930.5 CDJ57113.1 - 7 5.0 13.6 12 4.2 13.6 1.4 1 0 0 1 1 1 0 Putative porin Lip_prot_lig_C PF10437.9 CDJ57114.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus RskA PF10099.9 CDJ57115.1 - 4e-05 24.0 17.9 0.0025 18.1 15.6 4.6 2 2 1 4 4 4 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ57115.1 - 0.00025 20.8 15.9 0.00025 20.8 15.9 4.1 3 1 1 4 4 4 1 Spt20 family Rad60-SLD PF11976.8 CDJ57115.1 - 0.03 14.1 0.0 0.16 11.8 0.0 2.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_4 PF02390.17 CDJ57116.1 - 8e-11 41.7 0.0 1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CDJ57116.1 - 0.00037 21.1 0.0 0.00054 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ57116.1 - 0.0007 20.3 0.0 0.0012 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ57116.1 - 0.0045 17.0 0.0 0.0059 16.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDJ57116.1 - 0.0047 16.3 0.0 0.006 15.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CDJ57116.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ57116.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ57116.1 - 0.03 14.9 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CDJ57116.1 - 0.037 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 CDJ57116.1 - 0.087 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain SUIM_assoc PF16619.5 CDJ57116.1 - 0.17 11.9 8.3 0.26 11.4 8.3 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LMBR1 PF04791.16 CDJ57117.1 - 1.2 7.9 14.6 2 7.2 14.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S46 PF10459.9 CDJ57117.1 - 1.7 7.2 24.4 2.8 6.5 24.4 1.2 1 0 0 1 1 1 0 Peptidase S46 zf-CCCH PF00642.24 CDJ57118.1 - 7.1e-05 22.6 0.4 7.1e-05 22.6 0.4 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SUIM_assoc PF16619.5 CDJ57118.1 - 0.00051 20.1 2.2 0.00051 20.1 2.2 8.9 6 2 1 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_4 PF18044.1 CDJ57118.1 - 0.00055 19.7 0.3 0.0011 18.7 0.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ57118.1 - 0.0055 16.7 1.8 0.012 15.7 1.8 1.6 1 0 0 1 1 1 1 Zinc finger domain PAT1 PF09770.9 CDJ57118.1 - 8.5 4.5 65.3 0.9 7.7 24.3 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.29 CDJ57119.1 - 4.1e-29 101.6 0.1 2.7e-18 66.3 0.1 4.2 4 1 1 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ57119.1 - 5.1e-25 88.0 0.0 5.1e-25 88.0 0.0 4.3 4 1 0 4 4 4 1 Helicase conserved C-terminal domain RskA PF10099.9 CDJ57119.1 - 0.0073 16.6 24.9 0.023 15.0 5.4 4.6 4 2 0 4 4 4 2 Anti-sigma-K factor rskA ANAPC_CDC26 PF10471.9 CDJ57119.1 - 0.021 15.6 9.5 0.021 15.6 9.5 7.9 4 2 3 7 7 7 0 Anaphase-promoting complex APC subunit CDC26 TFIIA PF03153.13 CDJ57119.1 - 0.16 11.9 125.7 0.072 13.1 55.3 4.3 3 1 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_2 PF12679.7 CDJ57119.1 - 6.1 6.0 6.1 9.4 5.4 0.2 2.9 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4778 PF16008.5 CDJ57120.1 - 1.4 8.9 19.1 1.6 8.7 19.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CDC27 PF09507.10 CDJ57120.1 - 1.6 8.1 53.3 1.8 7.8 53.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DnaJ PF00226.31 CDJ57121.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain DUF3357 PF11837.8 CDJ57122.1 - 0.023 15.2 0.2 0.023 15.2 0.2 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) RskA PF10099.9 CDJ57122.1 - 0.076 13.3 47.6 0.1 12.9 8.3 5.0 2 2 3 5 5 5 0 Anti-sigma-K factor rskA DUF5113 PF17140.4 CDJ57123.1 - 0.5 10.2 5.8 7.8 6.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) LCD1 PF09798.9 CDJ57123.1 - 7.6 4.9 0.0 7.6 4.9 0.0 6.0 5 2 0 6 6 6 0 DNA damage checkpoint protein RskA PF10099.9 CDJ57126.1 - 0.0027 18.0 15.2 0.0041 17.4 15.2 1.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Raco_middle PF17651.1 CDJ57126.1 - 0.93 9.2 5.2 0.56 9.9 2.8 1.7 1 1 1 2 2 2 0 RACo middle region BAF1_ABF1 PF04684.13 CDJ57126.1 - 4.6 6.2 14.1 5.2 6.0 14.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IHABP4_N PF16174.5 CDJ57126.1 - 5.8 7.5 22.3 7.1 7.2 22.3 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal MRI PF15325.6 CDJ57128.1 - 0.66 11.1 3.9 1.5 10.0 3.9 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Phosphonate-bd PF12974.7 CDJ57129.1 - 0.011 15.3 0.3 0.092 12.3 0.2 2.2 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3439 PF11921.8 CDJ57130.1 - 1.3 9.0 13.1 4.9 7.1 13.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Otopetrin PF03189.13 CDJ57131.1 - 0.13 11.1 4.9 0.6 8.9 4.9 2.1 1 0 0 1 1 1 0 Otopetrin ABC2_membrane_2 PF12679.7 CDJ57131.1 - 0.24 10.6 4.1 0.42 9.9 0.7 3.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Tmp39 PF10271.9 CDJ57131.1 - 0.37 9.7 2.6 0.79 8.7 2.6 1.4 1 0 0 1 1 1 0 Putative transmembrane protein OATP PF03137.20 CDJ57131.1 - 0.4 8.9 7.7 0.081 11.2 2.5 2.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 CDJ57131.1 - 0.47 8.8 9.1 1.7 7.0 8.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Pkinase_fungal PF17667.1 CDJ57131.1 - 0.81 8.4 8.3 2.9 6.5 8.3 1.9 1 0 0 1 1 1 0 Fungal protein kinase Folate_carrier PF01770.18 CDJ57131.1 - 3 6.5 9.0 14 4.2 9.0 2.2 1 0 0 1 1 1 0 Reduced folate carrier Ureide_permease PF07168.11 CDJ57131.1 - 3.6 6.3 6.8 11 4.6 6.8 1.8 1 0 0 1 1 1 0 Ureide permease Cu_amine_oxid PF01179.20 CDJ57132.1 - 1.2e-70 238.6 0.1 2e-70 237.8 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.23 CDJ57132.1 - 1.8e-30 106.0 0.0 3.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Pur_ac_phosph_N PF16656.5 CDJ57132.1 - 0.12 12.9 0.2 6.3 7.4 0.0 3.3 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain SUIM_assoc PF16619.5 CDJ57132.1 - 0.2 11.7 5.1 0.59 10.2 5.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_25 PF13649.6 CDJ57133.1 - 3.5e-11 43.7 0.0 9.2e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDJ57133.1 - 2.3e-09 37.1 0.1 4.8e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CDJ57133.1 - 9.4e-09 35.2 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ57133.1 - 1.3e-08 35.4 0.0 3.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ57133.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ57133.1 - 0.00021 20.9 0.1 0.0004 20.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CDJ57133.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 CDJ57133.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 CDJ57133.1 - 0.003 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CDJ57133.1 - 0.0059 16.5 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.11 CDJ57133.1 - 0.0092 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CDJ57133.1 - 0.011 16.4 0.0 0.036 14.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CDJ57133.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 CDJ57133.1 - 0.04 13.8 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 CDJ57134.1 - 0.95 9.0 7.0 0.39 10.3 3.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ57135.1 - 9.5e-31 107.1 1.0 7e-30 104.3 0.0 2.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57135.1 - 5.1e-19 68.6 3.5 1.6e-18 67.0 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase PX PF00787.24 CDJ57137.1 - 8.1e-07 29.0 0.0 5.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 PX domain WD40 PF00400.32 CDJ57137.1 - 5.2e-06 27.1 4.5 0.036 15.0 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Menin PF05053.13 CDJ57137.1 - 0.0036 15.8 4.0 0.0036 15.8 4.0 2.1 2 0 0 2 2 2 1 Menin FAM60A PF15396.6 CDJ57137.1 - 0.12 12.4 15.7 0.3 11.0 9.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A MRC1 PF09444.10 CDJ57137.1 - 0.22 12.1 16.2 0.48 10.9 16.2 1.6 1 0 0 1 1 1 0 MRC1-like domain RR_TM4-6 PF06459.12 CDJ57137.1 - 0.7 9.7 17.8 0.58 9.9 14.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 CDJ57137.1 - 0.71 9.4 29.4 0.96 9.0 4.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ57137.1 - 1.9 7.4 21.5 18 4.2 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ57137.1 - 2.1 7.7 10.3 4.9 6.5 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Rtf2 PF04641.12 CDJ57137.1 - 4.6 6.5 16.7 12 5.2 0.2 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Presenilin PF01080.17 CDJ57137.1 - 6.6 5.4 28.2 2 7.1 0.6 2.1 2 0 0 2 2 2 0 Presenilin LMBR1 PF04791.16 CDJ57138.1 - 0.98 8.3 2.6 2.9 6.7 2.6 1.7 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2371 PF10177.9 CDJ57140.1 - 0.027 14.7 0.6 0.027 14.7 0.6 3.9 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2371) Actin PF00022.19 CDJ57141.1 - 8.2e-56 189.4 0.0 1.4e-54 185.3 0.0 1.9 1 1 0 1 1 1 1 Actin Sporozoite_P67 PF05642.11 CDJ57142.1 - 4.9e-06 24.9 0.0 4.9e-06 24.9 0.0 12.1 4 3 7 11 11 11 1 Sporozoite P67 surface antigen RskA PF10099.9 CDJ57142.1 - 0.0043 17.4 0.0 0.0043 17.4 0.0 25.8 6 5 11 19 19 19 4 Anti-sigma-K factor rskA PHD PF00628.29 CDJ57142.1 - 0.046 13.6 0.2 0.046 13.6 0.2 8.1 8 0 0 8 8 8 0 PHD-finger PHD_2 PF13831.6 CDJ57142.1 - 0.39 10.3 52.6 0.0095 15.5 3.5 6.3 6 0 0 6 6 6 0 PHD-finger DUF682 PF05081.12 CDJ57143.1 - 0.62 9.8 3.0 0.95 9.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Zip PF02535.22 CDJ57143.1 - 0.86 8.8 8.1 1.1 8.5 8.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 CDJ57143.1 - 2.6 6.8 26.5 3.3 6.5 26.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF572 PF04502.13 CDJ57143.1 - 2.7 7.5 26.4 3.6 7.1 26.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CDJ57143.1 - 3.4 7.2 28.8 4 7.0 28.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DNA_pol_phi PF04931.13 CDJ57144.1 - 5.7e-07 28.1 14.1 5.7e-07 28.1 14.1 5.1 4 1 1 5 5 5 3 DNA polymerase phi RskA PF10099.9 CDJ57144.1 - 5.5e-05 23.5 48.3 0.0012 19.2 1.6 5.5 3 2 2 5 5 5 3 Anti-sigma-K factor rskA Spore_III_AF PF09581.10 CDJ57144.1 - 0.00016 21.7 2.8 0.00016 21.7 2.8 4.5 3 1 1 4 4 4 1 Stage III sporulation protein AF (Spore_III_AF) DUF4834 PF16118.5 CDJ57144.1 - 0.00086 20.2 5.3 0.00086 20.2 5.3 7.9 7 1 1 8 8 8 2 Domain of unknown function (DUF4834) DUF4820 PF16091.5 CDJ57144.1 - 0.0014 18.0 5.6 0.0014 18.0 5.6 6.8 4 2 2 6 6 6 1 Domain of unknown function (DUF4820) DUF4207 PF13904.6 CDJ57144.1 - 0.012 15.4 1.1 0.012 15.4 1.1 5.9 5 2 0 5 5 5 0 Domain of unknown function (DUF4207) FerI PF08151.12 CDJ57144.1 - 0.31 11.2 0.1 0.31 11.2 0.1 5.4 5 3 0 5 5 5 0 FerI (NUC094) domain Lipase_GDSL PF00657.22 CDJ57144.1 - 0.36 10.8 0.0 0.36 10.8 0.0 3.4 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase DUF3328 PF11807.8 CDJ57144.1 - 0.5 10.1 0.0 0.11 12.2 1.8 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3328) TFIIA PF03153.13 CDJ57144.1 - 6.1 6.7 123.1 0.13 12.3 56.8 4.4 1 1 3 4 4 4 0 Transcription factor IIA, alpha/beta subunit YtxH PF12732.7 CDJ57145.1 - 0.021 15.4 2.6 0.021 15.4 2.6 2.5 2 0 0 2 2 2 0 YtxH-like protein Fmp27 PF10344.9 CDJ57145.1 - 0.33 9.0 5.1 0.51 8.4 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SKA1 PF07160.12 CDJ57145.1 - 0.86 9.4 15.1 0.31 10.9 3.0 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 XRN_N PF03159.18 CDJ57148.1 - 1.5e-68 230.8 0.0 2e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ57148.1 - 3.1e-10 39.6 3.7 7.5e-10 38.3 0.1 2.0 2 0 0 2 2 2 1 Xrn1 helical domain Acetate_kinase PF00871.17 CDJ57149.1 - 8.2 5.0 9.1 17 4.0 9.1 1.4 1 0 0 1 1 1 0 Acetokinase family TPR_1 PF00515.28 CDJ57150.1 - 1.1e-05 25.0 7.1 0.012 15.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ57150.1 - 3.2e-05 23.5 6.4 0.12 12.1 0.0 3.6 3 0 0 3 3 3 2 TPR repeat SUIM_assoc PF16619.5 CDJ57150.1 - 9.2e-05 22.4 0.0 9.2e-05 22.4 0.0 8.4 4 2 2 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 CDJ57150.1 - 0.044 13.9 0.1 0.044 13.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_6 PF13344.6 CDJ57151.1 - 1.4e-29 102.2 0.5 5.1e-29 100.4 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDJ57151.1 - 4.6e-13 49.0 0.1 2e-12 47.0 0.0 2.3 3 1 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 CDJ57151.1 - 3.1e-09 37.4 4.5 9.2e-05 22.8 0.1 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDJ57151.1 - 2.8e-05 24.3 0.5 0.022 14.8 0.0 3.0 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Ribosomal_L18p PF00861.22 CDJ57151.1 - 0.077 13.4 0.4 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Activator_LAG-3 PF11498.8 CDJ57151.1 - 2.4 7.0 13.9 4.2 6.2 13.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF5323 PF17257.2 CDJ57152.1 - 6.4e-06 25.9 4.5 1.5e-05 24.7 4.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5323) CTP_transf_1 PF01148.20 CDJ57153.1 - 4.1e-26 92.3 0.0 1.7e-25 90.3 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase family SID-1_RNA_chan PF13965.6 CDJ57153.1 - 0.15 10.5 3.5 0.47 8.8 0.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ57153.1 - 0.85 9.5 76.3 0.16 11.9 32.8 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ57153.1 - 8.4 6.3 9.7 2.2 8.2 0.4 3.0 2 1 0 2 2 2 0 N-glycosylation protein Androgen_recep PF02166.16 CDJ57154.1 - 0.00084 18.3 0.5 0.00084 18.3 0.5 7.3 3 2 4 8 8 8 1 Androgen receptor UVR PF02151.19 CDJ57154.1 - 8.8 6.2 10.2 0.64 9.9 3.5 2.6 2 0 0 2 2 2 0 UvrB/uvrC motif Fer2 PF00111.27 CDJ57155.1 - 1.1e-18 67.0 0.6 2.1e-18 66.0 0.6 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4834 PF16118.5 CDJ57155.1 - 1.1 10.3 2.9 9.1 7.3 2.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ57155.1 - 3.2 7.6 11.2 3.9 7.4 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AbiEi_1 PF09407.10 CDJ57156.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain DUF1180 PF06679.12 CDJ57157.1 - 0.31 11.4 0.1 0.31 11.4 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) ATP_bind_1 PF03029.17 CDJ57159.1 - 3.9e-69 233.1 0.1 1.4e-52 178.9 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CDJ57159.1 - 0.0008 19.3 0.0 0.093 12.5 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CDJ57159.1 - 0.022 15.2 0.0 0.054 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_3 PF01171.20 CDJ57160.1 - 2.4e-22 79.6 0.4 1.1e-12 48.1 0.0 3.7 1 1 2 3 3 3 3 PP-loop family Macoilin PF09726.9 CDJ57161.1 - 0.48 8.9 23.7 0.64 8.5 23.7 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDJ57161.1 - 1.3 6.1 21.6 1.4 5.9 21.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDRGK PF09756.9 CDJ57161.1 - 1.6 8.3 16.9 2.1 7.9 16.9 1.1 1 0 0 1 1 1 0 DDRGK domain CCSAP PF15748.5 CDJ57161.1 - 5 7.2 22.5 6.6 6.8 22.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Peptidase_S64 PF08192.11 CDJ57161.1 - 6.3 5.2 18.5 7.3 4.9 18.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 CDJ57161.1 - 6.5 6.2 23.7 8.5 5.8 23.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CDJ57162.1 - 0.066 12.8 0.3 0.066 12.8 0.3 4.1 2 1 2 4 4 4 0 Spt20 family DUF966 PF06136.13 CDJ57162.1 - 2 8.1 27.2 4.2 7.0 27.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dapper PF15268.6 CDJ57162.1 - 6.4 5.5 40.0 10 4.8 40.0 1.3 1 0 0 1 1 1 0 Dapper Rhomboid PF01694.22 CDJ57163.1 - 3.1e-23 82.4 13.9 4.6e-23 81.9 13.9 1.3 1 0 0 1 1 1 1 Rhomboid family RCC1_2 PF13540.6 CDJ57164.1 - 4.5e-06 26.3 6.7 0.0066 16.2 0.1 5.6 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ57164.1 - 0.00032 21.2 0.2 5 7.8 0.0 4.8 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Med3 PF11593.8 CDJ57164.1 - 0.0052 16.0 3.1 0.009 15.2 3.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3275 PF11679.8 CDJ57165.1 - 3.1 7.7 4.4 6.9 6.6 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) WD40 PF00400.32 CDJ57166.1 - 6.6e-17 61.6 11.8 7.6e-05 23.4 0.4 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57166.1 - 2.8e-09 37.1 0.0 0.28 11.5 0.0 5.9 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ57166.1 - 0.0077 15.2 0.2 0.08 11.9 0.0 2.5 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 CDJ57166.1 - 0.035 14.0 0.2 0.29 11.1 0.0 2.6 3 0 0 3 3 3 0 PQQ enzyme repeat RAB3GAP2_N PF14655.6 CDJ57166.1 - 0.084 12.1 9.3 0.39 9.9 0.0 3.8 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CDJ57166.1 - 0.18 10.4 0.8 0.42 9.2 0.2 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FTZ PF03867.14 CDJ57166.1 - 0.22 11.0 3.0 0.46 10.0 3.0 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Spt20 PF12090.8 CDJ57166.1 - 0.23 11.1 4.2 0.32 10.6 3.0 1.8 2 0 0 2 2 2 0 Spt20 family Ank_4 PF13637.6 CDJ57168.1 - 4.1e-26 91.0 0.1 2.2e-06 28.1 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ57168.1 - 1.3e-25 89.8 0.1 2e-08 34.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ57168.1 - 9.2e-21 73.3 2.4 2.4e-05 24.6 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 CDJ57168.1 - 1.9e-18 64.6 0.1 0.00013 22.1 0.0 6.5 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDJ57168.1 - 3.5e-17 62.2 1.7 1.2e-06 28.6 0.1 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) MDMPI_C PF07398.11 CDJ57168.1 - 0.049 14.5 0.5 0.13 13.1 0.5 1.8 1 0 0 1 1 1 0 MDMPI C-terminal domain UPF0180 PF03698.13 CDJ57168.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Orf78 PF06024.12 CDJ57168.1 - 1.6 9.1 3.1 1.5 9.2 0.1 2.5 4 0 0 4 4 4 0 Orf78 (ac78) eIF2A PF08662.11 CDJ57169.1 - 5.5e-15 55.7 2.4 2.1e-11 44.1 0.3 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CDJ57169.1 - 5.8e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRIM-19 PF06212.12 CDJ57169.1 - 0.24 11.3 2.3 0.75 9.7 2.3 1.8 1 0 0 1 1 1 0 GRIM-19 protein RskA PF10099.9 CDJ57170.1 - 0.0015 18.9 0.0 0.0015 18.9 0.0 18.8 5 5 5 11 11 11 3 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ57170.1 - 1.6 7.9 0.0 1.6 7.9 0.0 11.0 7 3 1 9 9 9 0 Sin-like protein conserved region eIF-3_zeta PF05091.12 CDJ57171.1 - 1.8e-104 350.6 0.0 2.2e-104 350.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CDJ57171.1 - 0.045 13.3 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus SDA1 PF05285.12 CDJ57172.1 - 9.9e-09 35.1 42.3 1.6e-06 27.8 32.3 2.5 2 0 0 2 2 2 2 SDA1 Caldesmon PF02029.15 CDJ57172.1 - 7.9e-07 28.2 25.9 7.9e-07 28.2 25.9 2.9 2 1 0 2 2 2 1 Caldesmon BUD22 PF09073.10 CDJ57172.1 - 0.0014 18.0 42.5 0.0014 18.0 42.5 3.0 2 1 0 2 2 2 1 BUD22 DUF5523 PF17661.1 CDJ57172.1 - 0.0042 16.8 36.7 0.0042 16.8 36.7 3.5 3 0 0 3 3 3 1 Family of unknown function (DUF5523) Presenilin PF01080.17 CDJ57172.1 - 0.47 9.2 46.1 0.21 10.3 4.1 2.4 2 0 0 2 2 2 0 Presenilin Wbp11 PF09429.10 CDJ57173.1 - 0.0022 18.4 10.0 0.0022 18.4 10.0 2.2 3 0 0 3 3 3 1 WW domain binding protein 11 DUF2722 PF10846.8 CDJ57173.1 - 0.1 11.5 9.8 0.052 12.5 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3533 PF12051.8 CDJ57173.1 - 0.12 11.3 2.4 0.19 10.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Herpes_UL32 PF06070.11 CDJ57173.1 - 1.3 6.7 7.5 2.4 5.8 7.5 1.4 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ribosomal_60s PF00428.19 CDJ57175.1 - 0.76 10.4 15.6 2.4 8.8 7.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein GREB1 PF15782.5 CDJ57175.1 - 8.9 3.3 36.2 0.027 11.6 9.2 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer DUF4667 PF15700.5 CDJ57176.1 - 0.00063 19.9 34.3 0.071 13.2 2.9 4.2 4 0 0 4 4 4 4 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ57176.1 - 0.0023 17.6 23.3 0.09 12.4 7.3 3.3 3 0 0 3 3 3 2 Spt20 family DUF1645 PF07816.11 CDJ57176.1 - 0.31 11.6 31.9 1.6 9.3 7.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) PAP2 PF01569.21 CDJ57176.1 - 0.78 9.5 5.1 3 7.6 0.0 3.0 3 0 0 3 3 3 0 PAP2 superfamily Actin PF00022.19 CDJ57177.1 - 1.7e-41 142.2 3.0 6.8e-33 113.9 0.4 4.1 2 1 1 3 3 3 3 Actin DUF2397 PF09660.10 CDJ57177.1 - 0.011 14.7 0.1 0.011 14.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF1676 PF07898.13 CDJ57177.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) IMUP PF15761.5 CDJ57177.1 - 0.15 12.8 58.0 1.1 10.0 8.3 4.8 5 0 0 5 5 5 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ57177.1 - 0.4 10.8 16.4 3.3 7.8 10.7 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ57178.1 - 0.0048 16.9 5.6 0.0048 16.9 5.6 5.5 3 2 1 4 4 4 2 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ57178.1 - 0.005 17.5 9.8 0.005 17.5 9.8 8.7 7 2 1 8 8 8 2 Peroxisomal membrane anchor protein (Pex14p) conserved region AXIN1_TNKS_BD PF16646.5 CDJ57178.1 - 0.048 14.6 0.3 0.048 14.6 0.3 5.9 5 1 1 6 6 6 0 Axin-1 tankyrase binding domain RskA PF10099.9 CDJ57179.1 - 0.00023 21.5 0.8 0.00023 21.5 0.8 2.0 1 1 1 2 2 2 2 Anti-sigma-K factor rskA RNase_H2_suC PF08615.11 CDJ57179.1 - 0.19 11.9 6.0 0.37 10.9 6.0 1.6 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Gram_pos_anchor PF00746.21 CDJ57179.1 - 1.4 9.0 7.4 4.6 7.3 1.5 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TFIIA PF03153.13 CDJ57179.1 - 4.3 7.2 34.4 5.8 6.8 34.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ57179.1 - 8.3 7.1 19.7 0.88 10.2 3.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.12 CDJ57180.1 - 0.00027 19.3 0.2 0.00039 18.8 0.2 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 CDJ57180.1 - 0.0027 17.8 5.4 0.0027 17.8 5.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ57180.1 - 0.0091 15.9 14.5 0.012 15.6 14.5 1.1 1 0 0 1 1 1 1 SPX domain Cwf_Cwc_15 PF04889.12 CDJ57180.1 - 0.016 15.0 7.4 0.027 14.2 7.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 CDJ57180.1 - 0.078 10.7 7.4 0.079 10.7 7.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spt20 PF12090.8 CDJ57180.1 - 0.22 11.1 13.9 0.29 10.7 13.9 1.1 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 CDJ57180.1 - 1.4 8.4 10.8 0.41 10.2 8.4 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ57180.1 - 1.4 7.6 9.8 1.8 7.3 9.8 1.2 1 0 0 1 1 1 0 Presenilin PNISR PF15996.5 CDJ57180.1 - 3.8 7.7 12.5 6.6 7.0 12.5 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 CDJ57180.1 - 4.4 7.3 5.1 6.3 6.8 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ57180.1 - 4.7 5.8 9.2 4.5 5.9 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RSRP PF17069.5 CDJ57180.1 - 5 6.6 31.5 0.031 13.8 17.8 2.3 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Apc15p PF05841.11 CDJ57180.1 - 6.7 7.5 13.7 3.8 8.3 3.4 2.4 2 0 0 2 2 2 0 Apc15p protein AAA_23 PF13476.6 CDJ57181.1 - 2.7 8.5 26.8 7.5 7.0 4.8 2.5 2 0 0 2 2 2 0 AAA domain RskA PF10099.9 CDJ57183.1 - 0.00011 22.5 34.6 0.0092 16.3 2.8 3.3 2 1 1 3 3 3 3 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ57183.1 - 0.0049 17.8 1.6 0.0049 17.8 1.6 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ57183.1 - 0.0082 15.1 14.7 0.0082 15.1 14.7 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ57183.1 - 0.017 15.5 25.1 0.12 12.8 1.3 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like CCSAP PF15748.5 CDJ57183.1 - 0.82 9.8 27.7 0.41 10.8 1.0 3.1 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated TCP PF03634.13 CDJ57183.1 - 0.86 10.2 26.7 0.49 10.9 1.0 3.2 3 0 0 3 3 3 0 TCP family transcription factor Connexin PF00029.19 CDJ57183.1 - 1.5 8.5 17.4 3.3 7.4 0.3 3.1 3 0 0 3 3 3 0 Connexin RR_TM4-6 PF06459.12 CDJ57183.1 - 2.2 8.0 21.1 1.1 9.1 1.4 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 AFT PF08731.11 CDJ57183.1 - 2.7 8.4 18.1 0.63 10.5 2.2 3.2 3 0 0 3 3 3 0 Transcription factor AFT SPX PF03105.19 CDJ57184.1 - 0.0039 17.2 3.7 0.0039 17.2 3.7 5.5 3 2 1 4 4 4 1 SPX domain CO_deh_flav_C PF03450.17 CDJ57185.1 - 0.26 11.5 7.3 0.08 13.1 1.0 2.4 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain DUF572 PF04502.13 CDJ57185.1 - 0.98 9.0 35.5 0.038 13.6 27.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Auxin_canalis PF05703.11 CDJ57185.1 - 4.3 7.2 45.4 0.041 13.8 21.1 2.3 2 0 0 2 2 2 0 Auxin canalisation DUF1779 PF08680.10 CDJ57185.1 - 5.6 7.1 16.3 3 8.0 13.1 2.0 2 0 0 2 2 2 0 TATA-box binding Spt20 PF12090.8 CDJ57186.1 - 0.00012 21.8 64.5 0.00071 19.3 25.7 2.1 2 0 0 2 2 2 2 Spt20 family SR-25 PF10500.9 CDJ57186.1 - 0.00021 21.0 8.1 0.076 12.6 3.5 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein FAM176 PF14851.6 CDJ57186.1 - 0.0009 18.9 17.0 0.0059 16.3 8.7 2.1 2 0 0 2 2 2 2 FAM176 family Presenilin PF01080.17 CDJ57186.1 - 0.0023 16.8 23.1 0.003 16.4 23.1 1.2 1 0 0 1 1 1 1 Presenilin Prothymosin PF03247.14 CDJ57186.1 - 0.0091 16.4 14.5 0.0091 16.4 14.5 2.2 2 0 0 2 2 2 1 Prothymosin/parathymosin family Vfa1 PF08432.10 CDJ57186.1 - 0.014 15.7 22.8 0.015 15.7 7.6 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 EPL1 PF10513.9 CDJ57186.1 - 0.027 14.9 22.3 0.25 11.7 8.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4770 PF15994.5 CDJ57186.1 - 0.039 14.2 21.7 0.4 10.9 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF1764 PF08576.10 CDJ57186.1 - 0.044 14.7 18.5 0.3 12.0 7.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Eapp_C PF10238.9 CDJ57186.1 - 0.062 13.4 23.6 0.18 11.9 8.8 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein FAM76 PF16046.5 CDJ57186.1 - 0.087 12.2 17.7 0.39 10.0 1.6 2.0 2 0 0 2 2 2 0 FAM76 protein Utp14 PF04615.13 CDJ57186.1 - 0.13 10.8 26.4 0.17 10.4 26.4 1.0 1 0 0 1 1 1 0 Utp14 protein BRF1 PF07741.13 CDJ57186.1 - 0.14 12.6 19.9 1.3 9.4 4.5 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4820 PF16091.5 CDJ57186.1 - 0.14 11.5 22.5 0.048 13.0 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4628 PF15429.6 CDJ57186.1 - 0.22 11.2 21.7 0.14 11.8 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Rxt3 PF08642.10 CDJ57186.1 - 0.22 12.3 13.6 0.43 11.3 2.4 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Myc_N PF01056.18 CDJ57186.1 - 0.22 11.4 22.3 0.37 10.7 22.3 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Slu7 PF11708.8 CDJ57186.1 - 0.23 11.2 30.3 0.3 10.8 15.2 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF3347 PF11827.8 CDJ57186.1 - 0.34 11.1 21.5 1.6 8.9 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) AIF_C PF14721.6 CDJ57186.1 - 0.38 11.1 23.2 0.56 10.6 8.7 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDC45 PF02724.14 CDJ57186.1 - 0.39 9.0 22.0 0.34 9.1 10.1 2.1 2 0 0 2 2 2 0 CDC45-like protein CD20 PF04103.15 CDJ57186.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 CD20-like family CSRNP_N PF16019.5 CDJ57186.1 - 0.44 10.4 22.2 0.63 9.9 9.7 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus XAP5 PF04921.14 CDJ57186.1 - 0.48 10.2 20.3 0.4 10.5 2.0 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Pet20 PF08692.10 CDJ57186.1 - 0.61 10.8 10.4 1.5 9.5 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF4746 PF15928.5 CDJ57186.1 - 0.66 9.3 24.3 0.22 10.9 12.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PRC2_HTH_1 PF18118.1 CDJ57186.1 - 0.7 10.7 19.9 1.1 10.1 7.6 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain CENP-B_dimeris PF09026.10 CDJ57186.1 - 0.73 10.3 13.2 0.35 11.3 9.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CobT PF06213.12 CDJ57186.1 - 0.73 9.2 43.8 1.5 8.2 22.7 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 CDJ57186.1 - 0.8 10.7 34.4 0.25 12.3 13.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RuvC_III PF18541.1 CDJ57186.1 - 0.8 9.6 17.8 0.56 10.1 5.6 2.1 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 RPN2_C PF18004.1 CDJ57186.1 - 0.81 9.6 26.3 0.23 11.4 12.4 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3464 PF11947.8 CDJ57186.1 - 1.2 8.9 27.1 1.7 8.4 11.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DDRGK PF09756.9 CDJ57186.1 - 1.4 8.5 35.5 1.9 8.0 8.7 2.1 2 0 0 2 2 2 0 DDRGK domain TERB2 PF15101.6 CDJ57186.1 - 1.4 8.9 34.3 1.4 8.9 13.7 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF5327 PF17261.2 CDJ57186.1 - 1.6 9.5 39.1 0.12 13.1 14.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) RXT2_N PF08595.11 CDJ57186.1 - 1.6 8.7 22.2 0.067 13.2 8.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal PPL5 PF18168.1 CDJ57186.1 - 1.7 7.8 21.6 0.29 10.4 9.8 2.1 2 0 0 2 2 2 0 Prim-pol family 5 NST1 PF13945.6 CDJ57186.1 - 1.8 8.6 30.5 0.94 9.6 11.6 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator FAM60A PF15396.6 CDJ57186.1 - 1.9 8.5 19.3 1 9.3 5.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Connexin PF00029.19 CDJ57186.1 - 1.9 8.2 20.2 1.5 8.5 7.2 2.1 2 0 0 2 2 2 0 Connexin Mak16 PF04874.14 CDJ57186.1 - 2 9.1 20.9 0.2 12.3 7.8 2.4 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF2981 PF11200.8 CDJ57186.1 - 2.5 7.8 12.5 3.2 7.4 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Dynactin_p62 PF05502.13 CDJ57186.1 - 2.6 6.7 16.2 0.45 9.2 4.9 2.0 2 0 0 2 2 2 0 Dynactin p62 family SelP_N PF04592.14 CDJ57186.1 - 2.8 7.3 21.4 3.4 7.0 9.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Bud13 PF09736.9 CDJ57186.1 - 2.8 8.3 28.5 5.1 7.5 12.2 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CLN3 PF02487.17 CDJ57186.1 - 2.9 6.9 17.4 1.1 8.2 5.1 2.1 2 0 0 2 2 2 0 CLN3 protein Pox_Ag35 PF03286.14 CDJ57186.1 - 3.1 7.6 24.1 0.096 12.5 12.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein EFTUD2 PF16004.5 CDJ57186.1 - 3.4 8.3 32.4 5.8 7.5 8.1 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus U1snRNP70_N PF12220.8 CDJ57186.1 - 3.8 8.2 23.9 0.91 10.2 6.3 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Nucleo_P87 PF07267.11 CDJ57186.1 - 4.1 6.1 25.0 5.3 5.8 25.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMEM51 PF15345.6 CDJ57186.1 - 4.4 7.1 32.0 3.3 7.5 11.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 F-protein PF00469.20 CDJ57186.1 - 4.6 6.8 24.1 2.7 7.5 10.6 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Porph_ging PF09697.10 CDJ57186.1 - 4.8 7.8 12.9 3.2 8.4 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Comm PF15957.5 CDJ57186.1 - 5.4 7.4 11.8 10 6.5 3.2 2.2 2 0 0 2 2 2 0 Commissureless CTU2 PF10288.9 CDJ57186.1 - 5.6 7.3 23.0 2.4 8.4 7.8 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 UPF0560 PF10577.9 CDJ57186.1 - 6.1 5.2 37.7 1.3 7.5 14.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Bul1_N PF04425.12 CDJ57186.1 - 6.9 5.3 20.5 1.5 7.5 7.6 2.0 2 0 0 2 2 2 0 Bul1 N terminus GNAT_acetyltr_2 PF13718.6 CDJ57186.1 - 7.1 6.0 18.4 6.4 6.1 4.0 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Ureide_permease PF07168.11 CDJ57186.1 - 7.2 5.2 13.5 1.1 7.9 3.3 2.1 2 0 0 2 2 2 0 Ureide permease DRY_EERY PF09750.9 CDJ57186.1 - 7.4 6.8 24.4 2.3 8.5 9.0 2.3 2 0 0 2 2 2 0 Alternative splicing regulator NPR3 PF03666.13 CDJ57186.1 - 7.9 5.1 22.8 3.4 6.4 11.5 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MPM1 PF17234.2 CDJ57186.1 - 8.3 6.6 29.9 6.5 7.0 12.3 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Sec62 PF03839.16 CDJ57186.1 - 8.6 5.8 18.1 5.2 6.5 6.8 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 EIIBC-GUT_N PF03612.14 CDJ57186.1 - 9.2 6.0 24.3 6.5 6.5 6.5 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AFT PF08731.11 CDJ57186.1 - 9.5 6.7 13.8 3.4 8.1 2.0 2.2 2 0 0 2 2 2 0 Transcription factor AFT zf-C3HC4_3 PF13920.6 CDJ57187.1 - 1.1e-09 37.9 9.5 1.1e-09 37.9 9.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ57187.1 - 2.6e-09 36.7 14.2 7.4e-09 35.3 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ57187.1 - 9.9e-09 35.4 15.1 9.9e-09 35.4 15.1 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ57187.1 - 3.7e-07 30.0 11.1 4.1e-07 29.9 8.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDJ57187.1 - 1.3e-06 28.1 11.2 1.3e-06 28.1 11.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ57187.1 - 1.1e-05 25.3 11.0 1.1e-05 25.3 11.0 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ57187.1 - 0.00015 21.8 12.4 0.00015 21.8 12.4 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDJ57187.1 - 0.00044 20.5 11.2 0.00044 20.5 11.2 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-NOSIP PF15906.5 CDJ57187.1 - 0.096 12.8 0.1 0.096 12.8 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein DUF4448 PF14610.6 CDJ57188.1 - 0.18 11.6 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) VPS13_C PF16909.5 CDJ57189.1 - 2.9e-24 85.8 0.3 6.6e-20 71.6 0.0 2.8 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CDJ57189.1 - 3.6e-05 24.0 0.0 0.00013 22.2 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 CDJ57189.1 - 0.00051 19.9 0.0 0.011 15.5 0.0 2.7 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDJ57189.1 - 0.0053 16.9 0.2 0.052 13.7 0.0 2.7 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 DSS1_SEM1 PF05160.13 CDJ57190.1 - 0.0056 16.7 22.7 0.24 11.5 22.7 2.3 1 1 0 1 1 1 1 DSS1/SEM1 family DEAD PF00270.29 CDJ57191.1 - 7.6e-38 130.0 0.0 2e-37 128.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ57191.1 - 6.6e-18 65.1 0.0 3.9e-17 62.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DSPc PF00782.20 CDJ57191.1 - 7.3e-12 45.2 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.19 CDJ57191.1 - 0.0066 16.3 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 Starch binding domain Ribosomal_L22e PF01776.17 CDJ57193.1 - 8.6e-45 151.6 2.4 1e-44 151.3 2.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family pP_pnuc_1 PF18165.1 CDJ57193.1 - 0.067 13.1 0.7 8.9 6.2 0.0 2.1 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease FERM_M PF00373.18 CDJ57193.1 - 0.11 13.0 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 FERM central domain AMPK1_CBM PF16561.5 CDJ57193.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase DUF3228 PF11539.8 CDJ57194.1 - 1.4e-56 191.1 0.1 2.6e-48 164.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3228) eIF3_p135 PF12807.7 CDJ57195.1 - 4.5e-08 33.3 0.1 1.2e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CDJ57195.1 - 0.038 14.3 2.7 1.9 8.8 0.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PWI PF01480.17 CDJ57197.1 - 2.1e-28 98.4 0.0 3.6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.18 CDJ57197.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain CALM_bind PF16025.5 CDJ57197.1 - 0.06 13.8 0.7 0.11 12.9 0.7 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DIRP PF06584.13 CDJ57197.1 - 0.061 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 DIRP PhoD PF09423.10 CDJ57198.1 - 0.00048 19.3 0.1 0.065 12.3 0.0 2.3 1 1 1 2 2 2 2 PhoD-like phosphatase DUF3496 PF12001.8 CDJ57198.1 - 0.032 14.6 0.3 0.07 13.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) TerD PF02342.18 CDJ57199.1 - 1.4e-06 27.9 0.0 1.8e-05 24.3 0.0 2.6 3 0 0 3 3 3 1 TerD domain Apolipoprotein PF01442.18 CDJ57199.1 - 0.053 13.4 4.3 0.22 11.4 2.3 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 CDJ57199.1 - 0.26 10.1 4.0 0.79 8.5 4.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Glutenin_hmw PF03157.13 CDJ57200.1 - 0.33 9.3 24.0 0.5 8.7 24.0 1.2 1 0 0 1 1 1 0 High molecular weight glutenin subunit SUIM_assoc PF16619.5 CDJ57201.1 - 0.004 17.2 0.2 0.004 17.2 0.2 7.4 4 3 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 CRT10 PF08728.10 CDJ57201.1 - 2.4 6.2 14.1 0.11 10.7 8.6 1.5 2 0 0 2 2 2 0 CRT10 Coilin_N PF15862.5 CDJ57201.1 - 9.8 6.0 33.1 0.052 13.3 2.5 3.9 4 0 0 4 4 4 0 Coilin N-terminus RskA PF10099.9 CDJ57202.1 - 0.0018 18.6 3.0 0.0018 18.6 3.0 6.5 1 1 4 5 5 5 2 Anti-sigma-K factor rskA DUF755 PF05501.11 CDJ57202.1 - 0.0035 17.6 13.4 0.0035 17.6 13.4 8.3 6 2 1 7 7 7 3 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ57203.1 - 0.0063 16.2 10.6 0.0063 16.2 10.6 11.0 7 3 1 11 11 11 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ57204.1 - 9.1e-06 24.9 9.7 9.1e-06 24.9 9.7 2.8 3 1 0 3 3 2 1 Protein of unknown function (DUF2722) DUF1645 PF07816.11 CDJ57204.1 - 0.0047 17.5 0.2 0.0047 17.5 0.2 3.9 3 1 1 4 4 1 1 Protein of unknown function (DUF1645) DUF719 PF05334.13 CDJ57204.1 - 0.0096 16.1 2.0 0.0096 16.1 2.0 3.4 3 1 1 4 4 2 1 Protein of unknown function (DUF719) YscJ_FliF_C PF08345.11 CDJ57204.1 - 0.066 13.6 0.0 0.066 13.6 0.0 3.6 2 2 0 2 2 1 0 Flagellar M-ring protein C-terminal LMBR1 PF04791.16 CDJ57204.1 - 0.074 11.9 9.9 0.026 13.4 5.9 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein Ferlin_C PF16165.5 CDJ57204.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.6 2 1 0 3 3 3 0 Ferlin C-terminus SLC12 PF03522.15 CDJ57204.1 - 0.69 8.9 20.9 0.19 10.7 1.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 FHIPEP PF00771.20 CDJ57204.1 - 0.88 8.0 9.7 1.3 7.4 0.2 2.2 2 0 0 2 2 2 0 FHIPEP family PepSY_TM PF03929.16 CDJ57204.1 - 2 8.0 10.2 0.69 9.5 1.3 2.4 2 1 0 2 2 2 0 PepSY-associated TM region PPP4R2 PF09184.11 CDJ57204.1 - 2.8 7.5 29.7 5.8 6.4 29.7 1.5 1 0 0 1 1 1 0 PPP4R2 DUF2052 PF09747.9 CDJ57204.1 - 2.9 8.0 16.8 0.47 10.5 5.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.13 CDJ57204.1 - 3.5 7.4 20.5 0.091 12.5 1.5 2.6 3 0 0 3 3 3 0 Band 3 cytoplasmic domain PRP1_N PF06424.12 CDJ57204.1 - 5 7.5 18.4 2.4 8.6 3.0 3.0 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal DUF2722 PF10846.8 CDJ57206.1 - 0.025 13.5 0.0 0.025 13.5 0.0 7.9 8 1 1 9 9 9 0 Protein of unknown function (DUF2722) Utp14 PF04615.13 CDJ57206.1 - 5.2 5.5 62.3 0.089 11.4 5.7 3.9 4 0 0 4 4 4 0 Utp14 protein DUF4632 PF15451.6 CDJ57209.1 - 0.055 13.5 0.5 0.2 11.7 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) XAP5 PF04921.14 CDJ57210.1 - 1.7e-32 113.3 9.2 1.7e-32 113.3 9.2 2.7 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF1635 PF07795.11 CDJ57210.1 - 0.0093 15.9 7.0 0.0093 15.9 7.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) DUF4614 PF15391.6 CDJ57210.1 - 0.25 11.3 18.7 0.58 10.1 18.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Miga PF10265.9 CDJ57210.1 - 0.59 9.0 9.8 1 8.2 9.8 1.4 1 0 0 1 1 1 0 Mitoguardin Pentapeptide_4 PF13599.6 CDJ57212.1 - 0.078 13.2 5.0 2.4 8.4 0.4 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) V_ATPase_I PF01496.19 CDJ57213.1 - 0.0017 16.4 8.6 0.0019 16.2 8.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2615 PF11027.8 CDJ57213.1 - 0.0018 18.4 0.1 0.0018 18.4 0.1 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF2615) Serinc PF03348.15 CDJ57213.1 - 0.0026 16.8 6.3 0.004 16.2 6.3 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Zip PF02535.22 CDJ57213.1 - 0.0037 16.5 6.0 0.0041 16.4 6.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 CDJ57213.1 - 0.0043 15.5 4.9 0.0059 15.1 4.9 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CCSAP PF15748.5 CDJ57213.1 - 0.0046 17.2 24.9 0.0055 16.9 24.9 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated HemX PF04375.14 CDJ57213.1 - 0.012 14.9 18.1 0.012 14.9 18.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FHIPEP PF00771.20 CDJ57213.1 - 0.013 14.0 2.8 0.013 14.1 2.8 1.2 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ57213.1 - 0.019 13.7 18.2 0.023 13.5 18.2 1.1 1 0 0 1 1 1 0 Presenilin Velvet PF11754.8 CDJ57213.1 - 0.026 14.5 18.4 0.032 14.2 18.4 1.2 1 0 0 1 1 1 0 Velvet factor TCP PF03634.13 CDJ57213.1 - 0.028 15.0 17.6 0.034 14.7 17.6 1.1 1 0 0 1 1 1 0 TCP family transcription factor ABC2_membrane_2 PF12679.7 CDJ57213.1 - 0.036 13.3 1.8 0.058 12.7 1.8 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein EOS1 PF12326.8 CDJ57213.1 - 0.075 13.0 7.0 0.11 12.5 7.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein Shisa PF13908.6 CDJ57213.1 - 0.095 12.9 16.2 0.12 12.6 16.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PA26 PF04636.13 CDJ57213.1 - 0.12 11.3 8.6 0.13 11.2 8.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF-3_zeta PF05091.12 CDJ57213.1 - 0.13 11.2 18.2 0.15 11.0 18.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RskA PF10099.9 CDJ57213.1 - 0.14 12.4 13.8 0.22 11.8 13.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ57213.1 - 0.17 11.5 20.0 0.57 9.8 20.0 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ac76 PF05814.11 CDJ57213.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.0 2 0 0 2 2 1 0 Orf76 (Ac76) Mito_fiss_reg PF05308.11 CDJ57213.1 - 0.2 11.7 19.5 0.25 11.4 19.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Dicty_REP PF05086.12 CDJ57213.1 - 0.21 9.5 18.4 0.24 9.3 18.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5385 PF17359.2 CDJ57213.1 - 0.46 10.0 16.6 8.6 5.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Endostatin PF06482.11 CDJ57213.1 - 0.67 9.4 18.2 0.81 9.1 18.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2828 PF11443.8 CDJ57213.1 - 0.69 7.9 10.5 0.65 8.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ57213.1 - 0.86 8.5 11.1 1.2 8.0 11.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1180 PF06679.12 CDJ57213.1 - 1.1 9.7 13.6 1.5 9.2 13.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4407 PF14362.6 CDJ57213.1 - 1.7 7.9 15.5 2 7.7 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM199X PF15814.5 CDJ57213.1 - 1.8 7.5 12.7 2.3 7.2 12.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X SLC12 PF03522.15 CDJ57213.1 - 1.9 7.4 16.3 2.2 7.2 16.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 eIF3_subunit PF08597.10 CDJ57213.1 - 2.2 8.1 17.7 2.7 7.8 17.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 CDJ57213.1 - 2.3 8.1 41.6 2.9 7.8 41.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRA PF06589.11 CDJ57213.1 - 2.4 8.3 4.6 1e+02 3.0 0.0 2.0 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Cellulose_synt PF03552.14 CDJ57213.1 - 2.7 6.4 4.6 2.4 6.5 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase PPP4R2 PF09184.11 CDJ57213.1 - 2.8 7.5 14.9 3.4 7.2 14.9 1.1 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.14 CDJ57213.1 - 2.8 7.8 26.7 3.2 7.6 26.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 CDJ57213.1 - 2.8 7.5 31.4 5.9 6.4 31.4 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ57213.1 - 3 6.1 12.0 3.9 5.8 12.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FAM176 PF14851.6 CDJ57213.1 - 3 7.5 11.2 63 3.2 11.8 2.0 2 0 0 2 2 2 0 FAM176 family ODV-E18 PF10717.9 CDJ57213.1 - 3.3 7.7 6.7 0.24 11.3 1.0 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Raftlin PF15250.6 CDJ57213.1 - 3.6 6.2 17.5 4.3 6.0 17.5 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 CDJ57213.1 - 3.8 5.7 16.1 4.3 5.5 16.1 1.0 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CDJ57213.1 - 4 6.2 12.7 4.4 6.0 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Apt1 PF10351.9 CDJ57213.1 - 4.6 6.0 17.7 5.9 5.6 17.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tim54 PF11711.8 CDJ57213.1 - 6.3 5.5 18.5 7 5.3 18.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ57215.1 - 0.012 15.2 1.5 0.012 15.2 1.5 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ57215.1 - 0.092 13.0 8.7 0.44 10.8 0.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ57215.1 - 0.4 11.1 13.9 0.57 10.7 13.9 1.2 1 0 0 1 1 1 0 AAA domain DUF4228 PF14009.6 CDJ57215.1 - 0.53 10.7 11.3 0.039 14.4 4.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Serinc PF03348.15 CDJ57215.1 - 0.59 9.0 5.5 0.78 8.6 5.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GET2 PF08690.10 CDJ57215.1 - 0.85 9.2 17.9 1.1 8.9 17.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4175 PF13779.6 CDJ57215.1 - 3.2 5.5 26.2 3.8 5.3 26.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EELM2 PF15863.5 CDJ57215.1 - 4.1 7.5 10.8 3.5 7.7 0.5 1.8 1 1 1 2 2 2 0 Extended EGL-27 and MTA1 homology domain DUF572 PF04502.13 CDJ57216.1 - 0.024 14.3 14.7 0.031 13.9 14.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 CDJ57216.1 - 3.6 6.4 8.0 6 5.7 8.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.7 CDJ57216.1 - 8.4 4.4 22.3 11 3.9 22.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 CDJ57217.1 - 0.0005 20.1 13.1 0.0005 20.1 13.1 3.3 2 1 0 2 2 2 1 SPX domain NAM-associated PF14303.6 CDJ57217.1 - 0.25 12.0 0.0 0.25 12.0 0.0 5.6 3 1 1 4 4 4 0 No apical meristem-associated C-terminal domain CNDH2_C PF16858.5 CDJ57219.1 - 3.6e-09 36.9 9.5 3.2e-08 33.8 9.5 2.9 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CDJ57219.1 - 0.00057 20.1 7.5 0.0012 19.0 0.0 2.8 3 0 0 3 3 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Spt20 PF12090.8 CDJ57219.1 - 0.0018 17.9 9.0 0.0018 17.9 9.0 2.4 2 0 0 2 2 2 2 Spt20 family SUIM_assoc PF16619.5 CDJ57219.1 - 0.0046 17.0 6.6 0.0046 17.0 6.6 3.7 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 MAP65_ASE1 PF03999.12 CDJ57219.1 - 0.06 12.0 8.7 0.095 11.4 8.7 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1635 PF07795.11 CDJ57219.1 - 0.13 12.1 9.6 0.017 15.0 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) GREB1 PF15782.5 CDJ57219.1 - 0.54 7.3 8.9 0.73 6.9 8.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Clr2 PF10383.9 CDJ57219.1 - 0.7 10.7 2.2 2.4 8.9 1.8 2.2 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 SPX PF03105.19 CDJ57219.1 - 1.5 8.7 14.1 0.19 11.6 8.9 2.0 2 0 0 2 2 2 0 SPX domain MITF_TFEB_C_3_N PF15951.5 CDJ57219.1 - 2.2 8.9 23.3 0.79 10.3 9.7 3.2 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus DUF755 PF05501.11 CDJ57219.1 - 8 6.8 23.2 0.2 11.9 15.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ57220.1 - 0.00014 21.5 12.0 0.00014 21.5 12.0 5.0 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 CDJ57221.1 - 0.0068 16.1 2.3 0.0068 16.1 2.3 3.0 2 1 0 2 2 1 1 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ57221.1 - 0.023 15.3 20.4 0.079 13.5 9.4 2.2 2 0 0 2 2 2 0 TCP family transcription factor EphA2_TM PF14575.6 CDJ57221.1 - 0.025 15.4 1.8 0.025 15.4 1.8 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2371 PF10177.9 CDJ57221.1 - 0.17 12.1 0.2 0.17 12.1 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Cytochrom_B_N_2 PF13631.6 CDJ57221.1 - 0.21 11.5 0.4 0.43 10.6 0.4 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Chorein_N PF12624.7 CDJ57221.1 - 0.22 11.7 6.8 0.38 10.9 6.8 1.4 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 DUF4448 PF14610.6 CDJ57221.1 - 0.23 11.2 2.7 0.46 10.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Hamartin PF04388.12 CDJ57221.1 - 0.69 8.5 31.4 0.78 8.3 31.4 1.0 1 0 0 1 1 1 0 Hamartin protein Bap31 PF05529.12 CDJ57221.1 - 0.7 9.8 3.9 1.2 8.9 3.9 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region SHR3_chaperone PF08229.11 CDJ57221.1 - 4.3 6.3 7.1 6.6 5.7 7.1 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4598 PF15370.6 CDJ57221.1 - 6.4 7.3 17.6 0.14 12.7 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) DUF4680 PF15730.5 CDJ57222.1 - 0.6 10.5 6.7 0.66 10.3 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) PAP1 PF08601.10 CDJ57223.1 - 0.0024 17.7 5.1 0.0024 17.7 5.1 4.0 2 2 0 2 2 1 1 Transcription factor PAP1 SR-25 PF10500.9 CDJ57223.1 - 0.0059 16.2 8.2 0.0059 16.2 8.2 6.1 5 2 1 7 7 7 1 Nuclear RNA-splicing-associated protein PNISR PF15996.5 CDJ57223.1 - 0.01 16.1 4.8 0.01 16.1 4.8 5.5 6 1 0 6 6 5 0 Arginine/serine-rich protein PNISR LCE PF14672.6 CDJ57223.1 - 0.017 15.7 4.1 0.017 15.7 4.1 5.8 5 0 0 5 5 4 0 Late cornified envelope DUF2126 PF09899.9 CDJ57223.1 - 0.055 11.5 7.2 0.17 9.9 7.2 1.9 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PPP4R2 PF09184.11 CDJ57223.1 - 0.056 13.0 5.0 0.22 11.1 5.0 2.0 1 1 0 1 1 1 0 PPP4R2 SpoIIP PF07454.11 CDJ57223.1 - 0.72 9.3 21.8 0.16 11.4 3.8 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) O-antigen_lig PF13425.6 CDJ57223.1 - 2.9 6.6 5.7 4.7 5.9 5.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GEN1_C PF18380.1 CDJ57223.1 - 3.1 8.7 9.0 5.5 7.9 0.1 3.5 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain eIF-3_zeta PF05091.12 CDJ57223.1 - 4.2 6.2 37.5 0.3 10.0 2.1 4.3 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 CDJ57223.1 - 5.3 6.2 12.1 10 5.2 2.8 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter Dala_Dala_lig_N PF01820.21 CDJ57223.1 - 5.6 7.5 6.5 67 4.0 0.4 4.0 5 0 0 5 5 5 0 D-ala D-ala ligase N-terminus DUF5094 PF17015.5 CDJ57223.1 - 7.6 6.6 14.1 0.37 10.9 1.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) FAM176 PF14851.6 CDJ57223.1 - 7.8 6.2 18.8 1.1 8.9 0.9 3.5 4 0 0 4 4 4 0 FAM176 family RRP7 PF12923.7 CDJ57224.1 - 1.9e-06 28.0 1.5 4.1e-06 26.9 1.5 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 CDJ57224.1 - 0.0065 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5093) RRM_7 PF16367.5 CDJ57224.1 - 0.031 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_Rrp7 PF17799.1 CDJ57224.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CDJ57224.1 - 0.046 13.5 0.3 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Caldesmon PF02029.15 CDJ57225.1 - 0.0013 17.6 7.5 0.0013 17.6 7.5 2.3 2 0 0 2 2 2 1 Caldesmon CDC45 PF02724.14 CDJ57225.1 - 8.2 4.6 51.3 1.5 7.0 8.5 2.3 2 0 0 2 2 2 0 CDC45-like protein HEAT PF02985.22 CDJ57226.1 - 0.00083 19.4 23.6 0.091 13.1 0.2 8.4 7 0 0 7 7 7 3 HEAT repeat TerC PF03741.16 CDJ57226.1 - 0.027 14.2 0.7 0.27 10.9 0.0 3.1 3 0 0 3 3 3 0 Integral membrane protein TerC family Arm PF00514.23 CDJ57226.1 - 2.6 8.2 21.6 0.11 12.6 0.3 6.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Ribosomal_S10 PF00338.22 CDJ57227.1 - 6.6e-26 90.4 0.1 7.7e-26 90.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.10 CDJ57227.1 - 0.02 15.2 0.1 0.048 14.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) Ribosomal_L35Ae PF01247.18 CDJ57228.1 - 3.3e-44 149.0 0.4 4e-44 148.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDJ57228.1 - 0.064 13.5 0.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 RimM N-terminal domain OMPdecase PF00215.24 CDJ57229.1 - 1.7e-08 34.3 0.0 1.3e-06 28.1 0.0 2.7 1 1 1 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HEAT PF02985.22 CDJ57229.1 - 2.2e-08 33.7 22.3 0.038 14.2 0.1 9.3 9 1 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 CDJ57229.1 - 6.5e-06 26.5 0.8 6.5e-06 26.5 0.8 8.6 9 0 0 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 CDJ57229.1 - 0.00017 21.4 1.3 0.00067 19.5 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CDJ57229.1 - 0.00024 21.4 23.8 0.63 10.5 0.5 7.9 6 3 1 7 7 7 3 HEAT repeats MMS19_C PF12460.8 CDJ57229.1 - 0.0013 18.0 0.3 7.2 5.6 0.0 4.3 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Herpes_IE68 PF02479.16 CDJ57229.1 - 0.0032 17.1 0.0 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 Herpesvirus immediate early protein PEARLI-4 PF05278.12 CDJ57229.1 - 0.54 9.8 2.1 0.87 9.1 0.1 2.2 3 0 0 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cohesin_HEAT PF12765.7 CDJ57229.1 - 1.1 9.6 6.3 33 4.9 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Proteasome PF00227.26 CDJ57230.1 - 2.3e-59 200.1 0.0 2.8e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ57230.1 - 2e-13 49.7 0.2 3.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.17 CDJ57230.1 - 0.032 14.4 0.1 0.075 13.2 0.0 1.6 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DSPc PF00782.20 CDJ57231.1 - 1e-24 86.9 0.0 1.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDJ57231.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDJ57231.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PK PF00224.21 CDJ57233.1 - 8.6e-128 426.1 2.5 1.3e-110 369.5 1.8 2.2 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 CDJ57233.1 - 6.9e-31 106.9 0.4 1.9e-30 105.5 0.4 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDJ57233.1 - 0.0027 16.9 0.8 0.0095 15.1 0.1 2.2 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.7 CDJ57233.1 - 0.048 13.2 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Dor1 PF04124.12 CDJ57234.1 - 9.9e-18 63.9 3.7 4.4e-10 38.8 0.6 2.5 3 0 0 3 3 3 2 Dor1-like family Vps51 PF08700.11 CDJ57234.1 - 0.064 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Sec1 PF00995.23 CDJ57235.1 - 6.6e-65 220.4 1.5 2.6e-47 162.3 0.4 2.0 1 1 1 2 2 2 2 Sec1 family Ribosomal_S26e PF01283.19 CDJ57236.1 - 2.2e-42 143.9 0.9 2.5e-42 143.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CDJ57236.1 - 0.016 15.8 1.5 0.032 14.8 1.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain JAB PF01398.21 CDJ57237.1 - 1.9e-25 89.1 0.4 8.2e-25 87.1 0.4 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDJ57237.1 - 6e-06 26.0 0.1 1.7e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDJ57237.1 - 0.02 15.0 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Allantoicase PF03561.15 CDJ57239.1 - 0.031 14.3 1.1 0.65 10.0 0.0 3.5 3 1 0 3 3 3 0 Allantoicase repeat DUF4713 PF15831.5 CDJ57240.1 - 0.19 12.2 1.6 0.5 10.9 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Autophagy_act_C PF03987.15 CDJ57241.1 - 1e-21 77.2 0.2 1.7e-21 76.6 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDJ57241.1 - 8.4e-13 47.6 2.4 1.3e-12 47.0 2.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RskA PF10099.9 CDJ57241.1 - 0.61 10.4 12.9 0.95 9.7 12.9 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ57242.1 - 0.00018 21.2 4.5 0.00018 21.2 4.5 1.1 1 0 0 1 1 1 1 Spt20 family Sin_N PF04801.13 CDJ57242.1 - 0.00048 19.5 2.7 0.00048 19.5 2.7 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region DUF2722 PF10846.8 CDJ57242.1 - 0.0013 17.8 4.0 0.0013 17.8 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RLL PF10036.9 CDJ57242.1 - 0.0086 16.0 1.2 0.0091 15.9 1.2 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Methyltransf_34 PF11312.8 CDJ57242.1 - 0.011 15.0 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TFIIE-A_C PF11521.8 CDJ57242.1 - 0.011 16.0 5.1 0.011 16.0 5.1 1.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha CDK2AP PF09806.9 CDJ57242.1 - 0.014 15.4 1.3 0.016 15.3 1.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.19 CDJ57242.1 - 0.018 15.6 22.2 0.24 12.0 10.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein EIIBC-GUT_N PF03612.14 CDJ57242.1 - 0.039 13.7 2.2 0.055 13.2 2.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ57242.1 - 0.045 12.5 1.1 0.038 12.8 1.1 1.1 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 CDJ57242.1 - 0.046 12.0 0.3 0.041 12.2 0.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DivIC PF04977.15 CDJ57242.1 - 0.049 13.4 9.0 0.061 13.1 9.0 1.1 1 0 0 1 1 1 0 Septum formation initiator ATG22 PF11700.8 CDJ57242.1 - 0.061 11.9 0.2 0.071 11.7 0.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF908 PF06012.12 CDJ57242.1 - 0.07 12.5 0.5 0.066 12.6 0.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) WRNPLPNID PF15017.6 CDJ57242.1 - 0.2 12.6 10.8 0.12 13.3 7.0 1.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box FHIPEP PF00771.20 CDJ57242.1 - 0.22 10.0 1.2 0.22 9.9 1.2 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4199 PF13858.6 CDJ57242.1 - 0.25 11.8 0.6 0.29 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CLN3 PF02487.17 CDJ57242.1 - 0.34 9.9 0.3 0.33 10.0 0.3 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 CDJ57242.1 - 0.37 11.8 6.7 0.53 11.3 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 CDJ57242.1 - 0.4 10.7 5.8 0.47 10.5 5.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Glt_symporter PF03616.14 CDJ57242.1 - 0.43 9.2 0.7 0.46 9.1 0.7 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Conotoxin PF02950.17 CDJ57242.1 - 0.43 11.6 1.5 0.37 11.8 0.6 1.4 2 0 0 2 2 1 0 Conotoxin OAD_gamma PF04277.13 CDJ57242.1 - 0.63 10.7 6.9 0.84 10.3 0.4 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Connexin PF00029.19 CDJ57242.1 - 0.73 9.5 4.9 0.89 9.3 4.9 1.1 1 0 0 1 1 1 0 Connexin UPF0560 PF10577.9 CDJ57242.1 - 0.76 8.2 7.2 0.91 8.0 7.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4820 PF16091.5 CDJ57242.1 - 0.87 8.9 6.8 1.2 8.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3464 PF11947.8 CDJ57242.1 - 0.94 9.2 6.2 1.5 8.6 6.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 CDJ57242.1 - 1.1 9.0 7.6 1.5 8.6 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Roughex PF06020.11 CDJ57242.1 - 1.2 8.2 7.3 1.2 8.1 7.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 CDJ57242.1 - 1.2 8.8 9.0 0.17 11.5 5.4 1.4 2 0 0 2 2 2 0 FAM176 family RRN9 PF10680.9 CDJ57242.1 - 1.9 8.8 6.8 0.26 11.6 2.7 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor V_ATPase_I PF01496.19 CDJ57242.1 - 3.2 5.5 6.5 3.8 5.3 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myc_N PF01056.18 CDJ57242.1 - 6.8 6.5 10.5 1 9.2 6.7 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Zip PF02535.22 CDJ57243.1 - 0.00077 18.8 1.9 0.0056 15.9 1.1 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter SUIM_assoc PF16619.5 CDJ57243.1 - 1.1 9.4 19.6 1.5 8.9 12.4 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ57244.1 - 2.8e-14 53.1 0.0 1.3e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Apt1 PF10351.9 CDJ57244.1 - 0.032 13.1 3.4 0.043 12.7 3.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_Tyr PF07714.17 CDJ57244.1 - 0.04 13.2 0.0 0.071 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Tmemb_cc2 PF10267.9 CDJ57244.1 - 1.4 8.0 4.1 1.7 7.7 4.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3824 PF12868.7 CDJ57245.1 - 0.039 14.6 4.7 0.039 14.6 4.7 3.9 4 0 0 4 4 4 0 Domain of unknwon function (DUF3824) K_channel_TID PF07941.11 CDJ57245.1 - 0.046 14.2 17.2 0.046 14.2 17.2 4.6 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain SMYLE_N PF18615.1 CDJ57245.1 - 0.34 10.4 29.3 0.12 11.9 17.4 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain GvpL_GvpF PF06386.11 CDJ57245.1 - 0.74 9.7 16.6 1.6 8.6 6.6 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Nop53 PF07767.11 CDJ57245.1 - 1.2 8.4 24.9 0.18 11.1 13.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ribosomal_60s PF00428.19 CDJ57245.1 - 3.3 8.3 20.6 2.6 8.7 5.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hamartin PF04388.12 CDJ57245.1 - 9 4.8 42.2 11 4.5 42.2 1.0 1 0 0 1 1 1 0 Hamartin protein DNMT1-RFD PF12047.8 CDJ57246.1 - 3.8e-07 30.2 0.0 8.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Auxin_resp PF06507.13 CDJ57246.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Auxin response factor RskA PF10099.9 CDJ57246.1 - 0.0052 17.1 0.0 0.0052 17.1 0.0 24.0 7 6 7 14 14 14 2 Anti-sigma-K factor rskA DDT PF02791.17 CDJ57246.1 - 0.11 12.9 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 DDT domain HECT PF00632.25 CDJ57247.1 - 8.8e-40 137.1 0.0 9.5e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ACDC PF14733.6 CDJ57247.1 - 0.037 14.3 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 AP2-coincident C-terminal PAP2_3 PF14378.6 CDJ57248.1 - 0.12 12.0 1.7 1.6 8.4 1.7 3.1 1 0 0 1 1 1 0 PAP2 superfamily BCS1_N PF08740.11 CDJ57250.1 - 0.015 15.3 0.4 0.015 15.3 0.4 2.3 2 1 0 2 2 2 0 BCS1 N terminal DUF572 PF04502.13 CDJ57250.1 - 2.8 7.5 26.1 2.1 7.9 4.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) tRNA-synt_1d PF00750.19 CDJ57252.1 - 3.8e-26 91.9 0.7 9e-15 54.5 0.0 3.5 2 1 1 3 3 3 3 tRNA synthetases class I (R) DALR_1 PF05746.15 CDJ57252.1 - 3.4e-13 49.8 0.3 3.2e-12 46.7 0.3 2.7 1 1 0 1 1 1 1 DALR anticodon binding domain SR-25 PF10500.9 CDJ57252.1 - 0.0035 17.0 1.9 0.0035 17.0 1.9 6.3 6 0 0 6 6 6 3 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ57252.1 - 0.017 15.4 50.2 0.67 10.2 9.7 5.9 3 1 2 6 6 6 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ57252.1 - 0.12 12.5 0.0 0.12 12.5 0.0 8.8 7 3 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 IMS PF00817.20 CDJ57254.1 - 5.3e-06 26.5 0.1 8.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDJ57254.1 - 0.094 13.4 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Myc_N PF01056.18 CDJ57254.1 - 0.61 9.9 4.8 1 9.2 4.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region tRNA-synt_2d PF01409.20 CDJ57256.1 - 1.3e-49 168.9 0.0 1.6e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 CDJ57256.1 - 3.1e-05 23.2 0.1 4.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 CDJ57256.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 CDJ57256.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) LMWPc PF01451.21 CDJ57257.1 - 1.8e-19 70.5 0.0 2.2e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ParB_C PF18064.1 CDJ57257.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Ribosomal_S15 PF00312.22 CDJ57260.1 - 1.6e-17 63.5 1.7 1.6e-17 63.5 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 TFIIA PF03153.13 CDJ57260.1 - 0.00045 20.4 11.0 0.00049 20.2 11.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ57260.1 - 0.0031 17.1 5.1 0.0049 16.5 5.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 CDJ57260.1 - 0.0046 16.1 16.3 0.0068 15.6 16.3 1.2 1 0 0 1 1 1 1 SprA-related family SMYLE_N PF18615.1 CDJ57260.1 - 0.017 14.7 3.6 0.018 14.6 3.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hamartin PF04388.12 CDJ57260.1 - 0.056 12.1 4.0 0.066 11.9 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein Roughex PF06020.11 CDJ57260.1 - 0.065 12.3 5.2 0.097 11.8 5.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DDHD PF02862.17 CDJ57260.1 - 0.12 12.5 3.1 0.15 12.2 3.1 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 CDJ57260.1 - 0.31 9.7 7.1 0.39 9.4 7.1 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ57260.1 - 0.34 9.6 4.6 0.42 9.3 4.6 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.10 CDJ57260.1 - 0.37 9.4 5.9 0.44 9.2 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 CDJ57260.1 - 0.38 10.3 10.8 0.55 9.8 10.8 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CDJ57260.1 - 0.39 10.7 6.2 0.55 10.2 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ57260.1 - 0.4 9.8 22.9 0.69 9.0 22.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM199X PF15814.5 CDJ57260.1 - 0.77 8.8 14.3 1.3 8.1 14.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X Spore_coat_CotO PF14153.6 CDJ57260.1 - 0.87 9.5 12.3 1.4 8.9 12.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Band_3_cyto PF07565.13 CDJ57260.1 - 1.2 8.9 5.5 0.93 9.2 4.4 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_hydro_9 PF00759.19 CDJ57260.1 - 1.4 8.3 15.2 1.7 8.0 15.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 CENP-U PF13097.6 CDJ57260.1 - 1.5 8.7 12.4 2.5 8.0 12.4 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit GREB1 PF15782.5 CDJ57260.1 - 3.2 4.7 7.4 3.7 4.5 7.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM214 PF10151.9 CDJ57260.1 - 3.9 5.8 8.2 5.6 5.3 8.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Coilin_N PF15862.5 CDJ57260.1 - 5.5 6.8 11.0 9.3 6.1 11.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Hid1 PF12722.7 CDJ57260.1 - 8.3 4.4 8.0 11 4.0 8.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMR_HSR1 PF01926.23 CDJ57261.1 - 8.8e-14 51.6 0.0 3.3e-13 49.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDJ57261.1 - 6.7e-07 29.0 0.5 0.0023 17.5 0.0 2.6 2 0 0 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 CDJ57261.1 - 1.4e-06 27.9 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_25 PF13481.6 CDJ57261.1 - 0.0014 18.3 1.4 0.0069 16.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 CDJ57261.1 - 0.015 15.2 0.1 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TFIIA PF03153.13 CDJ57261.1 - 0.34 10.9 50.4 0.16 11.9 40.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CDJ57261.1 - 5.1 7.2 27.7 0.13 12.4 11.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3015 PF11220.8 CDJ57261.1 - 7 6.5 7.8 14 5.5 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF4205 PF13898.6 CDJ57263.1 - 1.1e-32 113.3 0.0 1.1e-32 113.3 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4205) ABC2_membrane_2 PF12679.7 CDJ57263.1 - 0.043 13.1 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Amino_oxidase PF01593.24 CDJ57264.1 - 6.1e-26 91.7 22.4 5.9e-11 42.3 0.0 5.9 6 1 1 7 7 7 4 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ57264.1 - 5.1e-09 36.2 0.4 4.2e-08 33.3 0.4 2.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ57264.1 - 2.2e-05 23.8 0.1 5.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ57264.1 - 0.00061 18.6 1.2 0.00061 18.6 1.2 2.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CDJ57264.1 - 0.00076 20.0 2.2 0.0016 19.0 2.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ57264.1 - 0.065 12.5 1.2 0.12 11.6 1.2 1.3 1 0 0 1 1 1 0 Thi4 family Adenosine_kin PF04008.14 CDJ57265.1 - 0.0064 16.3 0.2 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Adenosine specific kinase Gp_dh_C PF02800.20 CDJ57266.1 - 1.8e-67 225.9 0.0 2.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDJ57266.1 - 6.2e-40 135.6 0.0 1.4e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CDJ57266.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HD_5 PF13487.6 CDJ57267.1 - 0.024 14.9 1.6 3.5 8.0 0.0 4.3 4 0 0 4 4 4 0 HD domain DUF5616 PF18481.1 CDJ57267.1 - 0.3 11.4 1.1 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) DnaJ PF00226.31 CDJ57268.1 - 8.5e-15 54.6 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RskA PF10099.9 CDJ57268.1 - 0.0045 17.3 2.1 0.011 16.0 0.9 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF1631 PF07793.11 CDJ57268.1 - 0.098 11.1 0.3 0.14 10.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CH_2 PF06294.11 CDJ57269.1 - 2.9e-15 56.2 0.0 3.2e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 CH-like domain in sperm protein RNA_pol_Rpb1_1 PF04997.12 CDJ57269.1 - 0.042 13.2 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Activator_LAG-3 PF11498.8 CDJ57269.1 - 1.4 7.9 20.2 0.9 8.4 1.2 2.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SpoU_methylase PF00588.19 CDJ57270.1 - 2.7e-08 34.1 0.0 4.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family PARP PF00644.20 CDJ57271.1 - 0.072 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 CDJ57272.1 - 1.7e-17 63.0 0.1 3.2e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_SPB PF02978.19 CDJ57272.1 - 0.031 14.9 0.7 0.031 14.9 0.7 1.7 2 1 0 2 2 2 0 Signal peptide binding domain HTH_33 PF13592.6 CDJ57272.1 - 0.16 11.7 0.5 0.34 10.6 0.5 1.5 1 0 0 1 1 1 0 Winged helix-turn helix TFIIA PF03153.13 CDJ57272.1 - 9.5 6.1 13.6 9.3 6.1 13.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OHA PF14418.6 CDJ57273.1 - 3.3e-15 55.7 0.0 9.9e-15 54.1 0.0 1.8 1 0 0 1 1 1 1 OST-HTH Associated domain OST-HTH PF12872.7 CDJ57273.1 - 0.035 13.9 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain SPRY PF00622.28 CDJ57274.1 - 6.3e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Cyclin_N PF00134.23 CDJ57275.1 - 0.019 14.7 0.5 0.019 14.7 0.5 5.2 6 0 0 6 6 6 0 Cyclin, N-terminal domain YdjM PF04307.14 CDJ57275.1 - 0.066 12.5 0.1 0.066 12.5 0.1 2.8 3 0 0 3 3 3 0 LexA-binding, inner membrane-associated putative hydrolase Vps51 PF08700.11 CDJ57275.1 - 0.16 12.0 0.1 0.16 12.0 0.1 3.4 3 0 0 3 3 3 0 Vps51/Vps67 DUF4231 PF14015.6 CDJ57275.1 - 0.28 11.7 3.3 0.41 11.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pkinase PF00069.25 CDJ57276.1 - 1.6e-09 37.5 0.0 3.1e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57276.1 - 0.0025 17.1 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 CDJ57276.1 - 0.84 10.3 15.0 1.4 9.5 1.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3446 PF11928.8 CDJ57276.1 - 5.9 7.3 11.4 8.9 6.7 2.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Porin_3 PF01459.22 CDJ57278.1 - 2.7e-16 59.8 0.1 3.1e-16 59.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin RskA PF10099.9 CDJ57282.1 - 2.1e-05 24.9 2.7 0.0031 17.8 0.1 6.9 4 2 2 6 6 6 2 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ57282.1 - 0.0038 18.2 0.4 0.0038 18.2 0.4 6.8 8 1 0 8 8 8 2 Domain of unknown function (DUF4834) EELM2 PF15863.5 CDJ57283.1 - 1.3e-34 119.8 4.6 1.2e-27 97.1 0.6 4.0 4 1 0 4 4 4 3 Extended EGL-27 and MTA1 homology domain Presenilin PF01080.17 CDJ57283.1 - 1.5 7.5 0.0 1.5 7.5 0.0 2.3 2 2 0 2 2 2 0 Presenilin Pkinase_Tyr PF07714.17 CDJ57284.1 - 0.00092 18.6 0.0 0.023 14.0 0.0 2.7 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ57284.1 - 0.0086 15.5 0.0 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1664 PF07889.12 CDJ57284.1 - 0.52 10.4 2.6 7.9 6.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.9 CDJ57285.1 - 0.028 14.3 0.9 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MmoB_DmpM PF02406.17 CDJ57285.1 - 0.12 12.7 0.4 0.21 11.8 0.4 1.5 1 0 0 1 1 1 0 MmoB/DmpM family FTR PF01913.18 CDJ57287.1 - 0.12 12.3 0.4 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase DUF2620 PF10941.8 CDJ57287.1 - 0.3 11.2 2.0 0.7 10.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF2620 DUF3835 PF12927.7 CDJ57288.1 - 3.2 8.7 7.3 0.61 11.0 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) PNP_UDP_1 PF01048.20 CDJ57289.1 - 3.3e-13 49.4 0.1 3.6e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CN_hydrolase PF00795.22 CDJ57289.1 - 0.11 11.8 0.0 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase NiFe-hyd_HybE PF11939.8 CDJ57290.1 - 8.2 6.3 16.1 0.42 10.5 7.5 3.1 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE HCO3_cotransp PF00955.21 CDJ57291.1 - 0.0039 16.1 2.4 0.0039 16.1 2.4 3.6 4 0 0 4 4 4 1 HCO3- transporter family Spt20 PF12090.8 CDJ57291.1 - 0.0094 15.6 1.3 0.0094 15.6 1.3 11.0 7 3 3 10 10 10 2 Spt20 family CDC45 PF02724.14 CDJ57292.1 - 0.21 9.9 24.0 0.066 11.5 20.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Latrophilin PF02354.16 CDJ57292.1 - 2.4 7.2 16.8 6.9 5.6 16.8 1.7 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region RAG1_imp_bd PF12560.8 CDJ57293.1 - 9.3 5.7 0.0 9.3 5.7 0.0 6.6 3 1 2 6 6 6 0 RAG1 importin binding RskA PF10099.9 CDJ57294.1 - 0.0052 17.1 5.8 0.0052 17.1 5.8 12.5 2 2 6 8 8 8 2 Anti-sigma-K factor rskA CNDH2_C PF16858.5 CDJ57294.1 - 5.6 6.7 38.9 2.4 7.9 2.8 3.6 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term WD40 PF00400.32 CDJ57295.1 - 0.095 13.6 4.4 19 6.3 0.4 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat TGT PF01702.18 CDJ57296.1 - 7.9e-07 28.5 0.2 2.4e-06 26.9 0.5 1.6 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase SR-25 PF10500.9 CDJ57296.1 - 3e-05 23.8 4.1 3e-05 23.8 4.1 8.0 5 3 2 7 7 7 2 Nuclear RNA-splicing-associated protein Lipase_GDSL PF00657.22 CDJ57296.1 - 0.00019 21.5 0.0 0.73 9.8 0.0 4.4 4 1 0 4 4 4 2 GDSL-like Lipase/Acylhydrolase RskA PF10099.9 CDJ57296.1 - 0.0044 17.3 11.3 0.0044 17.3 11.3 8.4 3 3 4 7 7 7 1 Anti-sigma-K factor rskA DUF913 PF06025.12 CDJ57296.1 - 4.3 6.2 44.3 0.14 11.2 1.8 4.4 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) DUF812 PF05667.11 CDJ57297.1 - 0.43 9.4 26.1 0.42 9.4 9.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Helicase_C PF00271.31 CDJ57298.1 - 5.1e-08 33.2 0.1 1.2e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ57298.1 - 0.00081 19.2 0.6 0.0022 17.8 0.6 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 CDJ57298.1 - 0.027 14.9 0.2 0.29 11.5 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 CDJ57298.1 - 0.06 13.7 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDJ57298.1 - 0.085 11.9 0.1 0.19 10.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HA2 PF04408.23 CDJ57298.1 - 1.2 9.4 3.8 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) AAA_23 PF13476.6 CDJ57298.1 - 2.8 8.4 4.5 0.71 10.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain ABC1 PF03109.16 CDJ57300.1 - 2e-14 53.8 0.0 3.4e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 ABC1 family RNA_GG_bind PF10258.9 CDJ57301.1 - 1.1e-21 76.6 0.0 2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain SNF2_N PF00176.23 CDJ57303.1 - 6.5e-49 166.5 0.0 9.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ57303.1 - 1e-12 48.4 0.0 3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ57303.1 - 5.3e-09 36.3 0.0 9.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ57303.1 - 0.00051 19.9 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDJ57303.1 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 CDJ57303.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase IL4 PF00727.18 CDJ57304.1 - 0.014 15.6 0.1 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 Interleukin 4 PEHE PF15275.6 CDJ57304.1 - 4.5 7.9 9.8 1.6 9.4 6.0 2.2 2 0 0 2 2 2 0 PEHE domain IMD PF08397.11 CDJ57304.1 - 4.8 6.5 10.5 0.39 10.1 4.0 2.4 2 1 1 3 3 3 0 IRSp53/MIM homology domain Vps51 PF08700.11 CDJ57305.1 - 5.7e-05 23.1 0.1 0.00017 21.6 0.0 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Baculo_PEP_C PF04513.12 CDJ57306.1 - 0.055 13.5 4.1 0.44 10.6 0.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELYS PF13934.6 CDJ57306.1 - 0.076 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly Glycos_transf_1 PF00534.20 CDJ57307.1 - 5.2e-18 65.2 0.0 1.5e-08 34.4 0.0 3.0 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ57307.1 - 1.1e-06 29.1 0.0 0.00021 21.8 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDJ57307.1 - 0.00013 22.1 0.0 0.00026 21.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 tRNA-synt_2b PF00587.25 CDJ57308.1 - 6.4e-19 68.6 0.0 9.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Kinesin PF00225.23 CDJ57309.1 - 1.2e-89 300.5 0.2 2e-89 299.8 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ57309.1 - 3.9e-15 56.1 0.4 3e-12 46.7 0.0 3.0 2 1 1 3 3 3 2 Microtubule binding SesA PF17107.5 CDJ57309.1 - 0.086 13.0 1.4 0.63 10.2 0.1 3.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CC2-LZ PF16516.5 CDJ57309.1 - 5.1 7.5 11.0 0.42 11.0 0.9 4.1 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator P5CR_dimer PF14748.6 CDJ57310.1 - 2.2e-33 114.6 2.0 3.9e-33 113.8 0.9 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CDJ57310.1 - 1.9e-07 31.5 0.2 7.6e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CagY_M PF07337.11 CDJ57310.1 - 0.0039 16.8 0.7 0.0039 16.8 0.7 1.7 2 0 0 2 2 2 1 DC-EC Repeat Sacchrp_dh_NADP PF03435.18 CDJ57310.1 - 0.017 15.3 0.1 0.032 14.5 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HATPase_c PF02518.26 CDJ57311.1 - 2.1e-06 28.2 0.1 2.9e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ57311.1 - 3.4e-06 26.9 0.1 5.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDWWSH PF15667.5 CDJ57312.1 - 1.8 8.0 8.3 2.3 7.6 8.2 1.3 1 1 0 1 1 1 0 Protein of unknown function with motif GDWWSH OTCace_N PF02729.21 CDJ57313.1 - 2.5e-35 121.7 3.6 3e-27 95.4 0.6 2.7 3 0 0 3 3 3 2 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CDJ57313.1 - 6.3e-08 32.8 0.1 4.4e-07 30.1 0.0 2.2 2 1 1 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF2722 PF10846.8 CDJ57313.1 - 0.00084 18.4 2.9 0.00084 18.4 2.9 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ57313.1 - 0.013 15.8 0.8 0.013 15.8 0.8 3.3 3 1 0 3 3 3 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ57313.1 - 1.2 9.8 6.1 7.3 7.2 0.6 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein AF-4 PF05110.13 CDJ57315.1 - 0.00068 17.9 14.8 0.00068 17.9 14.8 5.8 5 1 1 6 6 6 1 AF-4 proto-oncoprotein DUF2722 PF10846.8 CDJ57315.1 - 0.0037 16.3 5.7 0.0037 16.3 5.7 6.7 5 1 0 5 5 5 3 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ57315.1 - 0.0044 16.7 20.1 0.0044 16.7 20.1 10.6 9 2 2 11 11 11 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ57316.1 - 0.11 12.1 25.6 0.14 11.8 25.6 1.2 1 0 0 1 1 1 0 Spt20 family MPM1 PF17234.2 CDJ57316.1 - 0.17 12.1 7.4 0.22 11.8 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 MAP65_ASE1 PF03999.12 CDJ57316.1 - 0.34 9.6 16.3 0.42 9.3 16.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Peptidase_S30 PF01577.16 CDJ57316.1 - 0.5 9.9 7.0 0.56 9.8 7.0 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease CPSF100_C PF13299.6 CDJ57316.1 - 0.54 10.4 4.6 0.62 10.2 4.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4199 PF13858.6 CDJ57316.1 - 0.86 10.0 2.1 1 9.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TFIIA PF03153.13 CDJ57316.1 - 0.87 9.5 22.6 0.94 9.4 22.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ilar_coat PF01787.16 CDJ57316.1 - 0.97 9.2 7.2 1.1 9.0 7.2 1.0 1 0 0 1 1 1 0 Ilarvirus coat protein Cytochrom_B558a PF05038.13 CDJ57316.1 - 1.4 8.5 6.5 1.7 8.2 6.5 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Mcm10 PF09332.11 CDJ57316.1 - 1.7 8.0 11.0 1.8 7.9 11.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF4770 PF15994.5 CDJ57316.1 - 1.8 8.8 12.8 2 8.6 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Roughex PF06020.11 CDJ57316.1 - 2.4 7.2 13.1 2.6 7.1 13.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Band_3_cyto PF07565.13 CDJ57316.1 - 2.8 7.7 6.4 3.1 7.5 6.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.11 CDJ57316.1 - 3.5 6.9 8.1 4.3 6.7 8.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ57316.1 - 6.3 6.3 16.0 7.2 6.1 16.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Androgen_recep PF02166.16 CDJ57316.1 - 7.6 5.3 22.6 8.7 5.1 22.6 1.1 1 0 0 1 1 1 0 Androgen receptor ALMT PF11744.8 CDJ57316.1 - 8.2 5.1 5.7 8.6 5.1 5.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ57316.1 - 8.4 4.5 16.8 8.6 4.5 16.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ57316.1 - 9.5 3.2 13.0 10 3.1 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2407 PF10302.9 CDJ57318.1 - 0.2 12.2 7.6 0.45 11.1 0.0 3.5 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain RabGAP-TBC PF00566.18 CDJ57320.1 - 1.9e-40 138.8 8.4 4e-40 137.8 3.5 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3972 PF13118.6 CDJ57320.1 - 0.24 11.8 0.2 0.55 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) ZapB PF06005.12 CDJ57320.1 - 0.7 10.4 3.1 2.6 8.6 3.1 1.9 1 0 0 1 1 1 0 Cell division protein ZapB LAT2 PF15703.5 CDJ57321.1 - 0.034 14.0 1.7 0.046 13.6 1.7 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 DUF3619 PF12279.8 CDJ57321.1 - 0.084 13.2 1.2 0.16 12.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Presenilin PF01080.17 CDJ57321.1 - 2.6 6.7 4.0 3.1 6.5 4.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4481 PF14800.6 CDJ57324.1 - 0.19 11.2 0.4 0.27 10.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) SUI1 PF01253.22 CDJ57325.1 - 3.9e-17 62.6 0.2 9.1e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 TLD PF07534.16 CDJ57326.1 - 3.5e-22 79.1 0.2 1.4e-21 77.2 0.1 2.0 2 0 0 2 2 2 1 TLD Ribosomal_L29 PF00831.23 CDJ57327.1 - 2.4e-18 65.9 2.9 2.4e-18 65.9 2.9 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 CDJ57327.1 - 0.029 14.5 1.2 0.041 14.0 0.5 1.6 2 0 0 2 2 2 0 TolA binding protein trimerisation AAA_6 PF12774.7 CDJ57328.1 - 3.6e-132 440.3 0.0 1.2e-130 435.3 0.0 3.5 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ57328.1 - 1.4e-113 380.1 8.8 1.4e-113 380.1 8.8 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ57328.1 - 3.1e-109 366.1 7.1 3.1e-109 366.1 7.1 5.1 4 1 1 5 5 5 2 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CDJ57328.1 - 2.5e-68 229.5 0.2 2.5e-68 229.5 0.2 3.6 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ57328.1 - 2.8e-62 210.4 0.0 1.5e-61 208.0 0.0 2.4 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ57328.1 - 3.7e-48 164.3 0.6 1.1e-47 162.8 0.6 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDJ57328.1 - 1.1e-35 122.8 0.0 5e-29 101.1 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDJ57328.1 - 1.5e-33 116.0 0.0 3.3e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ57328.1 - 9.7e-31 106.3 0.1 1.1e-29 102.9 0.0 3.1 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDJ57328.1 - 1.5e-30 106.0 0.0 4.3e-11 43.0 0.0 6.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) MT PF12777.7 CDJ57328.1 - 4e-29 101.7 10.7 7e-29 100.9 10.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 CDJ57328.1 - 1.9e-15 57.5 0.2 0.0044 17.4 0.0 6.1 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ57328.1 - 5.9e-12 46.0 4.5 0.00072 19.8 0.0 7.7 7 1 1 8 8 6 1 AAA domain Dynein_AAA_lid PF17852.1 CDJ57328.1 - 2e-08 34.4 0.7 1.2e-05 25.4 0.7 3.1 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 CDJ57328.1 - 1.2e-07 32.4 0.2 7.9 7.0 0.0 5.7 5 0 0 5 5 4 0 AAA domain AAA_16 PF13191.6 CDJ57328.1 - 1.1e-06 29.2 8.4 5.1 7.4 0.0 7.3 6 1 0 7 7 4 0 AAA ATPase domain T2SSE PF00437.20 CDJ57328.1 - 8.4e-06 25.0 0.0 0.096 11.7 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 CDJ57328.1 - 6.2e-05 22.8 1.0 5.6 6.6 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 CDJ57328.1 - 6.6e-05 22.6 0.1 0.012 15.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CDJ57328.1 - 0.00037 20.3 0.2 0.23 11.2 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein TelA PF05816.11 CDJ57328.1 - 0.00049 19.3 4.8 0.00049 19.3 4.8 3.3 3 0 0 3 3 2 1 Toxic anion resistance protein (TelA) AAA_33 PF13671.6 CDJ57328.1 - 0.00071 19.8 7.0 0.74 10.0 0.0 5.2 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.6 CDJ57328.1 - 0.001 19.4 1.3 0.23 11.8 0.0 4.9 5 0 0 5 5 4 1 AAA domain Asn_synthase PF00733.21 CDJ57328.1 - 0.0059 16.3 0.2 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 Asparagine synthase Rad17 PF03215.15 CDJ57328.1 - 0.0071 16.3 0.7 19 5.1 0.0 4.6 6 0 0 6 6 4 0 Rad17 P-loop domain TsaE PF02367.17 CDJ57328.1 - 0.01 15.8 1.3 19 5.3 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDJ57328.1 - 0.02 15.3 0.1 1.2e+02 3.1 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_lid_1 PF17857.1 CDJ57328.1 - 0.022 15.0 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA+ lid domain Sigma54_activat PF00158.26 CDJ57328.1 - 0.023 14.4 0.0 58 3.3 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.19 CDJ57328.1 - 0.023 14.3 0.2 0.22 11.1 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 CDJ57328.1 - 0.027 14.2 0.0 3.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MPS2 PF17060.5 CDJ57328.1 - 0.044 13.0 9.8 0.24 10.6 2.7 2.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 Mg_chelatase PF01078.21 CDJ57328.1 - 0.064 12.6 7.4 6.7 6.0 0.0 4.6 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDJ57328.1 - 0.092 12.0 0.0 12 5.1 0.0 3.9 3 0 0 3 3 3 0 Zeta toxin ResIII PF04851.15 CDJ57328.1 - 0.11 12.5 0.8 10 6.1 0.0 4.0 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 CDJ57328.1 - 0.3 10.8 4.7 19 4.9 0.0 4.5 5 0 0 5 5 4 0 AAA domain NBD94 PF16830.5 CDJ57328.1 - 0.65 10.4 7.8 0.36 11.3 2.7 3.0 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH FAM76 PF16046.5 CDJ57328.1 - 0.83 8.9 10.4 0.36 10.2 1.9 2.6 2 0 0 2 2 2 0 FAM76 protein DALR_1 PF05746.15 CDJ57328.1 - 1.2 9.4 4.5 43 4.3 0.0 4.4 3 0 0 3 3 3 0 DALR anticodon binding domain ABC_tran PF00005.27 CDJ57328.1 - 1.6 9.3 9.7 19 5.8 0.0 5.3 6 0 0 6 6 3 0 ABC transporter PTPA PF03095.15 CDJ57328.1 - 2.2 7.7 5.2 0.6 9.5 0.3 2.6 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF4615 PF15393.6 CDJ57328.1 - 4.4 7.9 6.6 2.2 8.8 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Jnk-SapK_ap_N PF09744.9 CDJ57328.1 - 7 6.9 35.0 1.6 9.0 12.8 3.9 3 0 0 3 3 2 0 JNK_SAPK-associated protein-1 XRN_N PF03159.18 CDJ57329.1 - 1.1e-20 74.1 0.0 1.1e-19 70.8 0.0 2.4 1 1 1 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ57329.1 - 3.4e-06 26.3 1.7 0.0022 17.0 0.0 3.0 3 0 0 3 3 3 2 Xrn1 helical domain DAP_epimerase PF01678.19 CDJ57329.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase RskA PF10099.9 CDJ57331.1 - 0.00013 22.3 0.0 0.00022 21.5 0.0 1.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA RRP36 PF06102.12 CDJ57331.1 - 0.0046 16.9 21.6 0.0055 16.7 21.6 1.2 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 RR_TM4-6 PF06459.12 CDJ57331.1 - 0.043 13.7 22.4 0.052 13.4 22.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 CDJ57331.1 - 0.11 11.7 30.2 0.13 11.4 30.2 1.1 1 0 0 1 1 1 0 SprA-related family Paf1 PF03985.13 CDJ57331.1 - 0.12 11.4 29.5 0.13 11.2 29.5 1.1 1 0 0 1 1 1 0 Paf1 DUF2052 PF09747.9 CDJ57331.1 - 0.12 12.5 23.1 0.14 12.3 23.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MCM_bind PF09739.9 CDJ57331.1 - 0.14 10.6 16.4 0.15 10.5 16.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor eIF-3_zeta PF05091.12 CDJ57331.1 - 0.17 10.9 21.1 0.17 10.8 21.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Use1 PF09753.9 CDJ57331.1 - 0.18 11.5 20.3 0.21 11.2 20.3 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF648 PF04890.13 CDJ57331.1 - 0.35 10.6 8.9 0.43 10.3 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) CDC45 PF02724.14 CDJ57331.1 - 0.42 8.9 19.0 0.4 8.9 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 CDJ57331.1 - 0.48 9.5 18.3 0.64 9.1 18.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CDJ57331.1 - 0.59 10.1 27.6 0.68 9.9 27.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ57331.1 - 0.64 8.2 6.1 0.7 8.1 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) O-antigen_lig PF13425.6 CDJ57331.1 - 0.83 8.4 8.6 0.83 8.4 8.6 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Serinc PF03348.15 CDJ57331.1 - 0.84 8.5 8.9 1.1 8.2 8.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Saw1 PF11561.8 CDJ57331.1 - 1.1 8.7 12.2 1.5 8.3 12.2 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CCSAP PF15748.5 CDJ57331.1 - 1.2 9.3 24.4 1.4 9.0 24.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MAJIN PF15077.6 CDJ57331.1 - 1.2 8.9 14.1 1.3 8.7 14.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Sec62 PF03839.16 CDJ57331.1 - 1.4 8.4 15.3 1.7 8.1 15.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 CDJ57331.1 - 1.5 7.8 9.7 1.6 7.7 9.7 1.2 1 0 0 1 1 1 0 CLN3 protein Cellulose_synt PF03552.14 CDJ57331.1 - 1.9 6.9 8.2 2.3 6.6 8.2 1.0 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.17 CDJ57331.1 - 1.9 7.1 22.8 2.3 6.9 22.8 1.1 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 CDJ57331.1 - 2.4 6.4 6.5 2.5 6.4 6.5 1.1 1 0 0 1 1 1 0 Membrane transport protein SelP_N PF04592.14 CDJ57331.1 - 2.4 7.5 15.5 3 7.2 15.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3292 PF11696.8 CDJ57331.1 - 2.4 6.4 12.2 2.6 6.3 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FAM60A PF15396.6 CDJ57331.1 - 2.5 8.1 15.7 3 7.8 15.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CDJ57331.1 - 2.8 7.9 12.2 3.4 7.7 12.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC27 PF09507.10 CDJ57331.1 - 2.9 7.2 27.1 4.6 6.5 27.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S64 PF08192.11 CDJ57331.1 - 4.1 5.8 12.9 4.1 5.8 12.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Band_3_cyto PF07565.13 CDJ57331.1 - 4.1 7.1 12.9 4.6 7.0 12.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Afi1 PF07792.12 CDJ57331.1 - 4.9 7.7 18.5 7.3 7.1 18.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Suf PF05843.14 CDJ57331.1 - 5.4 6.9 18.3 6.1 6.7 18.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_11 PF13086.6 CDJ57331.1 - 5.9 6.6 17.4 7 6.4 17.4 1.1 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDJ57331.1 - 6.2 5.7 19.3 6.6 5.6 19.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 CDJ57331.1 - 6.5 5.7 11.7 7 5.6 11.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Endostatin PF06482.11 CDJ57331.1 - 6.7 6.1 14.1 7.9 5.8 14.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 CDJ57331.1 - 7.1 5.3 16.4 8.2 5.1 16.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 CDJ57331.1 - 7.2 5.5 9.4 7.9 5.3 9.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator VIR_N PF15912.5 CDJ57331.1 - 8.4 5.9 15.6 12 5.4 15.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 CDJ57331.1 - 9 5.4 13.4 9.7 5.3 13.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1980 PF09323.10 CDJ57331.1 - 9.4 6.1 9.4 11 5.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 CDJ57331.1 - 9.9 5.0 12.9 12 4.8 12.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Thioredoxin_8 PF13905.6 CDJ57332.1 - 1.1e-15 57.7 0.0 3.5e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Cas_Csn2 PF09711.10 CDJ57332.1 - 0.01 15.5 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) PI-PLC-X PF00388.19 CDJ57332.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF2722 PF10846.8 CDJ57334.1 - 7.9e-07 28.4 7.7 7.9e-07 28.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ57334.1 - 0.00052 18.8 13.3 0.00052 18.8 13.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ATG7_N PF16420.5 CDJ57334.1 - 0.033 13.8 0.9 0.038 13.6 0.9 1.1 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus PepSY_TM PF03929.16 CDJ57334.1 - 0.13 11.9 1.0 0.13 11.9 1.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region SpoIIP PF07454.11 CDJ57334.1 - 0.2 11.1 3.7 0.21 11.0 3.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MPM1 PF17234.2 CDJ57334.1 - 0.49 10.6 10.1 0.57 10.4 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ57334.1 - 1.6 7.4 6.3 1.7 7.3 6.3 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ57334.1 - 2 8.3 25.8 2.2 8.2 25.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ57334.1 - 2.9 7.8 14.3 3.3 7.6 14.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ57334.1 - 3.4 8.3 17.0 4.6 7.9 17.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 CDJ57334.1 - 4.1 7.1 6.5 5.1 6.8 6.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TERB2 PF15101.6 CDJ57334.1 - 5.2 7.1 12.5 6.3 6.8 12.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3464 PF11947.8 CDJ57334.1 - 8.7 6.1 8.4 11 5.8 8.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FHIPEP PF00771.20 CDJ57334.1 - 9.7 4.5 6.9 11 4.3 6.9 1.0 1 0 0 1 1 1 0 FHIPEP family DUF2722 PF10846.8 CDJ57335.1 - 0.011 14.7 5.0 0.011 14.7 5.0 4.1 3 1 1 4 4 1 0 Protein of unknown function (DUF2722) FAM60A PF15396.6 CDJ57335.1 - 0.045 13.8 24.1 0.83 9.6 17.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 CDJ57335.1 - 0.13 11.0 42.0 0.23 10.2 29.3 2.2 2 0 0 2 2 2 0 Presenilin TCP PF03634.13 CDJ57335.1 - 0.13 12.8 37.5 0.73 10.4 5.5 2.3 2 0 0 2 2 2 0 TCP family transcription factor RR_TM4-6 PF06459.12 CDJ57335.1 - 0.29 10.9 35.9 1.9 8.2 31.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MID_MedPIWI PF18296.1 CDJ57335.1 - 0.38 10.5 28.3 0.22 11.3 3.2 2.4 2 0 0 2 2 2 0 MID domain of medPIWI AF-4 PF05110.13 CDJ57335.1 - 0.65 8.0 45.3 0.049 11.7 9.7 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein eIF-3_zeta PF05091.12 CDJ57335.1 - 0.67 8.9 35.9 1.2 8.0 25.9 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_11 PF13086.6 CDJ57335.1 - 0.94 9.2 32.3 1.2 8.8 22.1 2.1 2 0 0 2 2 2 0 AAA domain Caldesmon PF02029.15 CDJ57335.1 - 1.2 7.9 39.0 1.4 7.6 31.3 2.2 2 0 0 2 2 2 0 Caldesmon Endostatin PF06482.11 CDJ57335.1 - 2.7 7.4 30.9 3.4 7.0 22.2 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin AAA_23 PF13476.6 CDJ57335.1 - 3.8 8.0 38.2 4.1 7.9 0.5 2.3 2 0 0 2 2 2 0 AAA domain Baculo_PP31 PF05311.11 CDJ57335.1 - 6.6 6.1 24.4 0.89 9.0 13.7 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Peroxin-3 PF04882.12 CDJ57335.1 - 8.8 5.2 36.4 1.4 7.8 27.8 2.2 2 0 0 2 2 2 0 Peroxin-3 Mit_KHE1 PF10173.9 CDJ57336.1 - 7.3 6.6 20.7 2.4 8.2 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related Glyco_hydro_9 PF00759.19 CDJ57337.1 - 0.16 11.4 17.1 51 3.1 17.1 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 PCB_OB PF17092.5 CDJ57338.1 - 0.0035 18.1 1.5 0.013 16.3 0.1 2.5 2 1 0 2 2 2 1 Penicillin-binding protein OB-like domain GET2 PF08690.10 CDJ57338.1 - 7.1 6.2 13.3 9.5 5.8 13.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Band_3_cyto PF07565.13 CDJ57338.1 - 10 5.9 11.8 6.5 6.5 10.1 1.4 1 1 1 2 2 2 0 Band 3 cytoplasmic domain IMCp PF12314.8 CDJ57339.1 - 0.0063 16.8 5.1 0.0063 16.8 5.1 4.4 2 1 3 5 5 5 3 Inner membrane complex protein RskA PF10099.9 CDJ57339.1 - 0.029 14.7 1.1 0.029 14.7 1.1 8.6 3 2 4 7 7 7 0 Anti-sigma-K factor rskA Orbi_VP3 PF01700.16 CDJ57339.1 - 0.59 8.0 5.9 0.87 7.4 5.9 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Reprolysin_3 PF13582.6 CDJ57341.1 - 0.017 15.7 0.1 0.028 14.9 0.1 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TFIIA PF03153.13 CDJ57341.1 - 0.32 10.9 8.8 0.34 10.8 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR19-TM PF15176.6 CDJ57342.1 - 0.017 15.1 1.1 0.017 15.1 1.1 4.4 2 1 2 4 4 4 0 Leucine-rich repeat family 19 TM domain DUF2722 PF10846.8 CDJ57343.1 - 0.14 11.1 0.0 0.14 11.1 0.0 6.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2722) EFG_C PF00679.24 CDJ57344.1 - 1.5e-08 34.5 0.0 0.00015 21.7 0.0 2.4 1 1 0 2 2 2 2 Elongation factor G C-terminus SPX PF03105.19 CDJ57344.1 - 0.0028 17.7 1.0 0.0036 17.3 1.0 1.3 1 0 0 1 1 1 1 SPX domain EFG_II PF14492.6 CDJ57344.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II Presenilin PF01080.17 CDJ57344.1 - 0.062 12.0 2.0 0.096 11.4 2.0 1.2 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 CDJ57344.1 - 0.12 12.9 15.3 0.43 11.2 15.3 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3299 PF11736.8 CDJ57344.1 - 0.18 11.8 0.6 0.4 10.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Transposase_22 PF02994.14 CDJ57344.1 - 0.28 11.4 1.5 1.6 9.0 0.5 2.1 2 0 0 2 2 2 0 L1 transposable element RBD-like domain DUF3123 PF11321.8 CDJ57344.1 - 4.8 7.9 7.8 17 6.1 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) SSP160 PF06933.11 CDJ57344.1 - 8.5 4.4 18.6 15 3.6 18.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cupin_2 PF07883.11 CDJ57345.1 - 0.0084 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain GP120 PF00516.18 CDJ57345.1 - 4.5 5.8 5.1 1.7 7.1 0.4 2.2 2 0 0 2 2 2 0 Envelope glycoprotein GP120 Peptidase_S46 PF10459.9 CDJ57345.1 - 9.9 4.7 17.0 0.04 12.6 7.7 1.6 2 0 0 2 2 2 0 Peptidase S46 Clathrin_lg_ch PF01086.17 CDJ57346.1 - 5.2e-09 36.5 47.6 1e-08 35.6 47.6 1.5 1 1 0 1 1 1 1 Clathrin light chain PAT1 PF09770.9 CDJ57346.1 - 1.5 7.0 44.0 2.2 6.5 44.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorion_2 PF03964.15 CDJ57346.1 - 3.6 8.5 13.9 0.19 12.6 2.0 2.5 2 1 0 2 2 2 0 Chorion family 2 MCM PF00493.23 CDJ57347.1 - 2.7e-62 209.8 0.1 1.8e-57 194.0 0.1 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 CDJ57347.1 - 2.6e-25 88.6 0.3 5.8e-25 87.5 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CDJ57347.1 - 1.9e-20 73.0 0.0 3.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CDJ57347.1 - 2.2e-08 34.6 0.0 2.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDJ57347.1 - 3.2e-05 23.4 0.0 9.5e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 CDJ57347.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain AAA_5 PF07728.14 CDJ57347.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ57347.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Myc_N PF01056.18 CDJ57348.1 - 0.035 14.0 0.2 0.035 14.0 0.2 4.1 3 1 1 4 4 4 0 Myc amino-terminal region HATPase_c_5 PF14501.6 CDJ57348.1 - 0.73 9.8 2.9 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 GHKL domain SDA1 PF05285.12 CDJ57348.1 - 6.6 6.1 31.6 3.1 7.1 7.3 2.9 2 1 0 2 2 2 0 SDA1 Mucin PF01456.17 CDJ57350.1 - 8.3 6.4 26.6 2.7 8.0 7.5 2.8 2 0 0 2 2 2 0 Mucin-like glycoprotein TFIIA PF03153.13 CDJ57351.1 - 0.0018 18.3 25.2 0.0018 18.3 25.2 6.3 2 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ57351.1 - 0.0021 18.4 6.8 0.0021 18.4 6.8 13.0 5 4 3 9 9 9 3 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ57352.1 - 0.027 14.5 22.9 0.032 14.2 22.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ57352.1 - 4.1 8.4 6.1 9 7.3 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ57353.1 - 0.0012 19.1 9.1 0.0012 19.1 9.1 3.7 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF4667 PF15700.5 CDJ57353.1 - 0.25 11.4 15.3 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) RcpC PF16976.5 CDJ57353.1 - 0.31 11.1 0.1 0.31 11.1 0.1 3.5 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB Spt20 PF12090.8 CDJ57353.1 - 2.9 7.4 21.0 3.7 7.1 17.8 2.1 2 0 0 2 2 2 0 Spt20 family Spt20 PF12090.8 CDJ57354.1 - 0.00027 20.6 8.1 0.00027 20.6 8.1 7.7 5 2 2 7 7 7 3 Spt20 family Dehydrin PF00257.19 CDJ57354.1 - 0.0024 18.5 2.4 0.0024 18.5 2.4 11.6 7 4 2 9 9 9 1 Dehydrin Apt1 PF10351.9 CDJ57354.1 - 0.079 11.8 0.1 0.079 11.8 0.1 6.1 4 1 0 4 4 4 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ57355.1 - 0.00033 20.3 13.9 0.00033 20.3 13.9 11.2 6 3 3 10 10 10 2 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ57359.1 - 0.12 12.5 16.5 1.2 9.3 16.5 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF382 PF04037.13 CDJ57360.1 - 2.8e-24 85.7 0.2 5.7e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 CDJ57360.1 - 6.8e-19 67.5 7.1 1.2e-18 66.7 7.1 1.4 1 0 0 1 1 1 1 PSP A1_Propeptide PF07966.12 CDJ57360.1 - 0.62 10.0 3.2 1.5 8.8 3.2 1.7 1 0 0 1 1 1 0 A1 Propeptide DUF4248 PF14053.6 CDJ57361.1 - 0.27 11.3 0.0 0.27 11.3 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4248) zf-HIT PF04438.16 CDJ57362.1 - 3.5e-08 33.2 12.3 6.6e-08 32.3 12.3 1.4 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.14 CDJ57362.1 - 6.4e-05 21.4 13.8 6.4e-05 21.4 13.8 2.1 2 0 0 2 2 2 1 CDC45-like protein BSP_II PF05432.11 CDJ57362.1 - 7.9e-05 22.5 14.6 7.9e-05 22.5 14.6 2.3 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 CDJ57362.1 - 0.00093 19.4 44.9 0.0099 16.0 24.7 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 CDJ57362.1 - 0.0057 16.5 25.8 0.0081 16.0 7.5 2.2 2 0 0 2 2 2 2 AAA domain Presenilin PF01080.17 CDJ57362.1 - 0.035 12.9 33.8 0.078 11.7 14.8 2.2 2 0 0 2 2 2 0 Presenilin eIF-3c_N PF05470.12 CDJ57362.1 - 0.073 11.4 21.0 0.35 9.1 21.0 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SURF6 PF04935.12 CDJ57362.1 - 0.098 12.4 46.6 0.25 11.1 19.1 2.2 2 0 0 2 2 2 0 Surfeit locus protein 6 zf-MYND PF01753.18 CDJ57362.1 - 0.14 12.3 14.0 0.4 10.8 14.0 1.8 1 0 0 1 1 1 0 MYND finger SID-1_RNA_chan PF13965.6 CDJ57362.1 - 0.24 9.8 8.9 0.82 8.0 3.5 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 BUD22 PF09073.10 CDJ57362.1 - 0.53 9.6 43.7 0.019 14.3 21.1 2.3 2 1 0 2 2 2 0 BUD22 FmiP_Thoc5 PF09766.9 CDJ57362.1 - 0.65 9.2 43.2 0.27 10.5 16.5 3.4 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 CDC27 PF09507.10 CDJ57362.1 - 1 8.7 41.5 1.7 8.0 22.7 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CobT PF06213.12 CDJ57362.1 - 1.4 8.3 54.6 0.46 9.8 6.1 3.0 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT DUF3402 PF11882.8 CDJ57362.1 - 1.8 7.6 27.1 1.2 8.2 8.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) PAT1 PF09770.9 CDJ57362.1 - 3 6.0 42.4 0.69 8.1 14.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF250_C PF12031.8 CDJ57362.1 - 5.6 6.2 8.1 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa DUF3801 PF12687.7 CDJ57362.1 - 6.5 6.8 42.4 4.9 7.2 18.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) ABATE PF07336.11 CDJ57362.1 - 9.8 6.9 8.1 25 5.5 1.1 2.6 3 0 0 3 3 2 0 Putative stress-induced transcription regulator Rad60-SLD_2 PF13881.6 CDJ57363.1 - 6.8e-07 29.4 0.0 6.8e-07 29.4 0.0 4.4 3 2 1 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDJ57363.1 - 1.9e-06 27.5 0.0 1.9e-06 27.5 0.0 3.7 4 1 0 4 4 4 1 Ubiquitin family YukD PF08817.10 CDJ57363.1 - 0.00025 21.7 0.2 0.002 18.8 0.2 2.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 CDJ57363.1 - 0.0012 18.7 0.7 0.0054 16.5 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like MRAP PF15183.6 CDJ57364.1 - 0.42 10.6 3.8 3.4 7.7 0.3 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Adaptin_N PF01602.20 CDJ57365.1 - 3.9e-22 78.5 1.5 2.2e-20 72.7 0.1 2.6 3 0 0 3 3 3 2 Adaptin N terminal region AP4E_app_platf PF14807.6 CDJ57365.1 - 1.1e-09 38.5 1.2 3.1e-09 37.1 0.4 2.2 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform SUIM_assoc PF16619.5 CDJ57365.1 - 1.1 9.4 35.4 0.87 9.7 5.3 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 K_channel_TID PF07941.11 CDJ57367.1 - 0.031 14.7 2.2 0.031 14.7 2.2 9.0 6 3 3 9 9 9 0 Potassium channel Kv1.4 tandem inactivation domain DUF3381 PF11861.8 CDJ57368.1 - 1.1 9.0 3.9 4.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) LZ_Tnp_IS66 PF13007.7 CDJ57368.1 - 3.1 8.7 12.9 2.8 8.8 0.1 3.8 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain Hydrolase_4 PF12146.8 CDJ57371.1 - 1.8e-21 76.5 0.0 5.5e-15 55.3 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ57371.1 - 2.2e-12 46.9 0.0 5.1e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ57371.1 - 2.4e-12 48.0 0.5 2.6e-10 41.3 0.3 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ57371.1 - 9.3e-12 45.1 0.1 1.2e-08 34.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 CDJ57371.1 - 2.7e-06 26.3 0.3 0.0019 17.0 0.2 3.1 3 1 1 4 4 4 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 CDJ57371.1 - 6.7e-06 25.8 0.0 4.7e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family PGAP1 PF07819.13 CDJ57371.1 - 9.9e-05 22.2 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.12 CDJ57371.1 - 0.00029 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 CDJ57371.1 - 0.001 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 CDJ57371.1 - 0.0018 17.9 0.0 0.027 14.1 0.0 2.4 1 1 2 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 CDJ57371.1 - 0.002 17.8 0.0 0.008 15.9 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 CDJ57371.1 - 0.0028 17.6 0.0 0.0091 15.9 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 CDJ57371.1 - 0.0041 17.0 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 CDJ57371.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ57371.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ57371.1 - 0.015 15.1 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CDJ57371.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 CDJ57371.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF818 PF05677.12 CDJ57371.1 - 0.2 10.5 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Adap_comp_sub PF00928.21 CDJ57372.1 - 2.7e-09 36.8 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ57372.1 - 0.13 12.2 0.1 0.31 10.9 0.1 1.7 2 0 0 2 2 2 0 Clathrin adaptor complex small chain HAUS5 PF14817.6 CDJ57373.1 - 0.029 13.2 35.3 0.056 12.2 35.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 TctA PF01970.16 CDJ57374.1 - 0.0012 17.7 2.5 0.0012 17.7 2.5 1.8 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family Cation_efflux PF01545.21 CDJ57374.1 - 0.0084 15.9 0.8 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 Cation efflux family DUF4064 PF13273.6 CDJ57374.1 - 0.057 13.7 4.3 0.58 10.5 2.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Pox_A14 PF05767.12 CDJ57374.1 - 0.53 10.5 8.4 0.1 12.8 2.5 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RskA PF10099.9 CDJ57375.1 - 0.0055 17.0 0.0 0.0055 17.0 0.0 20.6 13 3 6 20 20 20 3 Anti-sigma-K factor rskA GCP_N_terminal PF17681.1 CDJ57376.1 - 8.7e-35 120.8 4.0 2.6e-24 86.4 0.0 3.1 3 0 0 3 3 3 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDJ57376.1 - 2e-20 73.5 14.0 2e-20 73.5 14.0 3.2 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal Pro_isomerase PF00160.21 CDJ57377.1 - 1.7e-47 161.6 0.1 1.9e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cnd1 PF12717.7 CDJ57380.1 - 0.068 13.2 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF2232 PF09991.9 CDJ57380.1 - 0.21 10.7 1.8 0.45 9.6 0.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) TFIIA PF03153.13 CDJ57380.1 - 0.37 10.7 8.9 0.43 10.5 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AbiEi_3 PF11459.8 CDJ57380.1 - 0.38 10.5 3.5 1 9.0 2.8 1.8 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Phage_r1t_holin PF16945.5 CDJ57381.1 - 0.0017 18.5 1.8 0.0017 18.5 1.8 3.5 4 0 0 4 4 4 1 Putative lactococcus lactis phage r1t holin RskA PF10099.9 CDJ57381.1 - 0.025 14.9 26.0 1.1 9.6 8.5 3.1 1 1 0 2 2 2 0 Anti-sigma-K factor rskA PMEI PF04043.15 CDJ57381.1 - 5.7 7.3 21.9 1.7 9.0 3.3 3.1 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor DFRP_C PF16543.5 CDJ57382.1 - 2.6e-19 69.5 4.8 2.6e-19 69.5 4.8 3.9 3 1 1 4 4 4 2 DRG Family Regulatory Proteins, Tma46 eIF-3_zeta PF05091.12 CDJ57384.1 - 6.7 5.6 47.6 0.0065 15.5 23.7 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 CDJ57385.1 - 0.27 11.2 26.7 0.5 10.3 26.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ57386.1 - 4.3 7.0 6.3 6.1 6.5 1.8 2.7 3 0 0 3 3 3 0 Connexin Peptidase_S49_N PF08496.10 CDJ57386.1 - 6.4 6.8 6.9 2.7 8.1 2.1 2.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal UPF0051 PF01458.17 CDJ57387.1 - 9.1e-46 156.3 0.2 1.6e-45 155.5 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Spt20 PF12090.8 CDJ57387.1 - 0.023 14.3 6.4 0.059 13.0 1.2 2.4 2 0 0 2 2 2 0 Spt20 family DUF2052 PF09747.9 CDJ57387.1 - 0.38 10.8 5.1 5.2 7.2 0.6 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) HTH_38 PF13936.6 CDJ57388.1 - 0.47 10.3 10.3 22 4.9 0.0 6.4 5 2 1 6 6 6 0 Helix-turn-helix domain Ribosomal_S7 PF00177.21 CDJ57389.1 - 3.3e-09 36.6 0.0 4.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Phage_r1t_holin PF16945.5 CDJ57389.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Ecl1 PF12855.7 CDJ57390.1 - 0.007 17.6 8.1 0.007 17.6 8.1 4.8 3 1 1 4 4 4 1 ECL1/2/3 zinc binding proteins CS PF04969.16 CDJ57390.1 - 0.02 15.9 0.0 0.042 14.9 0.0 1.5 1 0 0 1 1 1 0 CS domain DUF4171 PF13775.6 CDJ57390.1 - 8.2 6.9 35.0 0.078 13.4 7.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4171) TRAPP PF04051.16 CDJ57393.1 - 3.7e-31 107.8 0.0 4.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Protein_K PF12283.8 CDJ57393.1 - 0.037 14.3 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage protein K DUF2268 PF10026.9 CDJ57393.1 - 0.053 13.1 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PNISR PF15996.5 CDJ57394.1 - 0.0018 18.6 13.4 0.0031 17.8 13.4 1.4 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR Ndc1_Nup PF09531.10 CDJ57394.1 - 0.007 15.1 10.2 0.0077 15.0 10.2 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.12 CDJ57394.1 - 0.017 13.7 27.3 0.022 13.4 27.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 CDJ57394.1 - 0.059 11.9 12.4 0.071 11.7 12.4 1.1 1 0 0 1 1 1 0 Macoilin family CCSAP PF15748.5 CDJ57394.1 - 0.061 13.5 19.2 0.097 12.8 19.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ57394.1 - 0.37 9.0 22.1 0.47 8.7 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.14 CDJ57394.1 - 0.44 10.5 10.7 0.71 9.8 10.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 CDJ57394.1 - 1 7.5 15.9 1.3 7.2 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 CDJ57394.1 - 2.7 7.9 9.9 4.2 7.3 9.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SDA1 PF05285.12 CDJ57394.1 - 3.2 7.1 24.7 4.4 6.6 24.7 1.1 1 0 0 1 1 1 0 SDA1 DUF4551 PF15087.6 CDJ57394.1 - 4.1 6.1 15.9 5.4 5.7 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 CDJ57394.1 - 4.1 6.1 18.5 6.3 5.5 18.5 1.3 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 CDJ57394.1 - 5.1 6.3 26.5 7 5.9 26.5 1.1 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 CDJ57394.1 - 5.5 4.0 14.9 6.8 3.7 14.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ57394.1 - 6.8 6.1 20.0 9.6 5.7 20.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPRY PF00622.28 CDJ57395.1 - 0.0033 17.5 0.0 0.0033 17.5 0.0 4.4 4 2 0 4 4 4 1 SPRY domain EMP24_GP25L PF01105.24 CDJ57396.1 - 3.3e-30 105.4 0.0 4.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FtsJ PF01728.19 CDJ57397.1 - 6.1e-11 42.7 1.6 1.8e-09 38.0 1.6 3.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase SNF PF00209.18 CDJ57397.1 - 0.038 12.7 0.1 0.066 11.9 0.1 1.3 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family UCH PF00443.29 CDJ57400.1 - 3.5e-30 105.4 0.0 4.7e-29 101.6 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ57400.1 - 5.4e-08 32.8 2.8 6.5e-06 26.0 1.1 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Radical_SAM PF04055.21 CDJ57401.1 - 3.6e-17 63.2 0.0 1.3e-16 61.5 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM_C PF16199.5 CDJ57401.1 - 3.7e-17 62.1 0.0 8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain tRNA-synt_2 PF00152.20 CDJ57402.1 - 3.4e-79 266.2 0.0 4.5e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDJ57402.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDJ57402.1 - 4.9e-08 32.8 0.0 2.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 CDJ57402.1 - 0.75 8.6 5.5 1.2 8.0 5.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA-synt_2c PF01411.19 CDJ57403.1 - 3.3e-194 646.5 0.0 3.8e-192 639.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDJ57403.1 - 4.3e-16 58.7 0.1 9.6e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDJ57403.1 - 3.7e-05 24.2 1.9 9.2e-05 22.9 1.9 1.7 1 0 0 1 1 1 1 DHHA1 domain RRM_1 PF00076.22 CDJ57404.1 - 2.2e-27 94.7 0.1 1.1e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ57404.1 - 3.3e-06 27.1 0.1 0.0019 18.3 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ57404.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BSD PF03909.17 CDJ57406.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 BSD domain DUF2052 PF09747.9 CDJ57408.1 - 0.047 13.8 28.9 0.84 9.7 21.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Connexin PF00029.19 CDJ57408.1 - 0.77 9.5 6.2 0.39 10.4 3.7 1.7 2 0 0 2 2 2 0 Connexin RskA PF10099.9 CDJ57408.1 - 1.7 8.9 12.2 10 6.4 12.2 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CPSF100_C PF13299.6 CDJ57408.1 - 2.1 8.5 13.6 6.9 6.8 10.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HA2 PF04408.23 CDJ57408.1 - 2.3 8.5 4.9 5.5 7.3 2.4 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) V_ATPase_I PF01496.19 CDJ57408.1 - 2.6 5.8 6.3 3.4 5.5 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_hydro_3_C PF01915.22 CDJ57408.1 - 5.2 6.9 8.2 1.5 8.8 0.4 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain SUIM_assoc PF16619.5 CDJ57409.1 - 0.00064 19.7 4.3 0.00064 19.7 4.3 9.6 5 2 2 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 Caldesmon PF02029.15 CDJ57409.1 - 0.0024 16.7 21.7 0.0024 16.7 21.7 4.1 4 0 0 4 4 4 2 Caldesmon DUF737 PF05300.11 CDJ57409.1 - 0.0064 16.9 0.6 0.0064 16.9 0.6 7.1 3 2 1 6 6 6 1 Protein of unknown function (DUF737) NAPRTase_C PF17956.1 CDJ57411.1 - 6.8e-22 78.0 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 CDJ57411.1 - 3.6e-13 49.7 0.0 1.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CDJ57411.1 - 5.1e-05 23.7 0.0 0.00014 22.3 0.0 1.7 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Presenilin PF01080.17 CDJ57412.1 - 0.0031 16.3 32.7 0.0031 16.3 32.7 2.7 2 1 0 2 2 2 1 Presenilin Hamartin PF04388.12 CDJ57412.1 - 3.5 6.2 45.0 0.033 12.9 27.3 2.2 2 0 0 2 2 2 0 Hamartin protein EnY2 PF10163.9 CDJ57414.1 - 1.8e-07 31.4 0.2 2.9e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 tRNA-synt_2b PF00587.25 CDJ57415.1 - 5.1e-32 111.3 0.0 4.2e-30 105.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ57415.1 - 4.6e-18 65.1 0.3 1.1e-17 63.9 0.2 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 CDJ57415.1 - 4.6e-12 45.8 0.0 9.6e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GBV-C_env PF12786.7 CDJ57415.1 - 0.0036 16.1 0.6 0.0069 15.1 0.6 1.4 1 0 0 1 1 1 1 GB virus C genotype envelope TGS PF02824.21 CDJ57415.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain Asp-Al_Ex PF06826.12 CDJ57415.1 - 0.09 12.6 0.4 0.66 9.8 0.2 2.2 2 0 0 2 2 2 0 Predicted Permease Membrane Region OAD_gamma PF04277.13 CDJ57415.1 - 0.48 11.1 2.2 31 5.3 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MMPL PF03176.15 CDJ57415.1 - 0.91 8.4 2.8 0.9 8.4 0.1 2.0 2 0 0 2 2 2 0 MMPL family MlrC_C PF07171.12 CDJ57416.1 - 9.3 6.4 7.0 0.65 10.2 2.0 1.6 2 0 0 2 2 2 0 MlrC C-terminus PhoLip_ATPase_C PF16212.5 CDJ57417.1 - 1.6e-31 110.0 5.3 1.6e-31 110.0 5.3 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDJ57417.1 - 2e-08 33.8 0.9 2e-08 33.8 0.9 2.9 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDJ57417.1 - 4.3e-08 32.9 5.1 0.0035 16.9 0.0 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 CDJ57417.1 - 3.7e-07 30.7 0.0 0.0093 16.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ57417.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MtrA PF04208.14 CDJ57417.1 - 0.012 15.3 0.6 0.025 14.2 0.6 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A YcbB PF08664.10 CDJ57417.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 YcbB domain TPR_19 PF14559.6 CDJ57419.1 - 3.7e-14 53.0 22.3 0.00068 20.1 0.0 8.1 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ57419.1 - 8.3e-12 44.3 19.3 0.024 14.7 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ57419.1 - 9.3e-09 35.4 22.9 0.053 13.8 1.0 7.0 5 2 3 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDJ57419.1 - 1.3e-08 35.3 11.4 0.094 13.4 0.0 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ57419.1 - 4.4e-08 33.2 7.4 0.056 14.1 0.1 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ57419.1 - 1.3e-06 28.7 16.0 0.59 11.1 0.0 8.4 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ57419.1 - 2.7e-06 26.9 16.5 0.15 11.9 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ57419.1 - 7e-06 26.2 13.8 0.23 11.8 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ57419.1 - 0.0015 18.9 0.2 0.0015 18.9 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ57419.1 - 0.0038 17.3 3.8 2.8 8.1 0.0 5.0 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDJ57419.1 - 0.011 15.4 4.6 0.4 10.3 0.1 3.4 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 CDJ57419.1 - 0.018 15.4 4.0 4.9 7.6 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ57419.1 - 0.032 14.4 2.3 27 5.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ57419.1 - 0.058 13.4 8.7 6.6 7.0 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ57419.1 - 0.21 12.0 1.7 7.7 7.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ57419.1 - 0.24 11.6 7.2 10 6.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ57419.1 - 0.64 10.0 14.5 0.12 12.3 0.8 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SUI1 PF01253.22 CDJ57420.1 - 4e-16 59.3 0.1 9.8e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 GAD PF02938.14 CDJ57420.1 - 0.11 12.8 0.0 6.8 7.0 0.0 2.5 2 0 0 2 2 2 0 GAD domain Pre-PUA PF17832.1 CDJ57421.1 - 2e-10 41.2 0.0 1.3e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Pre-PUA-like domain Aldo_ket_red PF00248.21 CDJ57423.1 - 1.9e-39 135.6 0.0 1.9e-37 129.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1663 PF07909.11 CDJ57423.1 - 0.17 10.6 0.5 0.57 8.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1663) AMP-binding PF00501.28 CDJ57425.1 - 0.25 9.9 7.8 7.6 5.0 5.9 2.4 1 1 1 2 2 2 0 AMP-binding enzyme MMR1 PF08505.10 CDJ57425.1 - 0.49 10.6 49.3 0.023 15.0 23.3 2.6 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein NUDIX_4 PF14815.6 CDJ57425.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.6 3 2 0 3 3 3 0 NUDIX domain Zip PF02535.22 CDJ57425.1 - 1.7 7.8 18.3 0.014 14.6 3.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF812 PF05667.11 CDJ57425.1 - 3.2 6.5 40.2 0.048 12.5 32.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) zf-C2HC5 PF06221.13 CDJ57427.1 - 0.041 13.9 3.2 0.16 11.9 1.1 2.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CBS PF00571.28 CDJ57428.1 - 2.4e-08 34.3 0.1 3.4e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 CBS domain Spt20 PF12090.8 CDJ57428.1 - 0.002 17.8 30.1 0.0098 15.5 3.2 2.1 2 0 0 2 2 2 2 Spt20 family ANAPC_CDC26 PF10471.9 CDJ57428.1 - 0.0021 18.8 21.3 0.25 12.2 2.5 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CDJ57428.1 - 0.083 11.8 23.0 0.15 11.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ57428.1 - 0.2 12.0 11.4 0.82 10.0 5.7 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4834 PF16118.5 CDJ57428.1 - 0.36 11.8 17.6 2.1 9.4 10.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4484 PF14831.6 CDJ57428.1 - 0.58 10.2 4.6 22 5.0 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) SUIM_assoc PF16619.5 CDJ57428.1 - 0.66 10.1 29.8 0.035 14.2 3.1 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 CDJ57428.1 - 0.74 8.7 13.3 0.22 10.4 5.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.8 CDJ57428.1 - 1.9 8.2 5.4 5.7 6.7 3.2 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Band_3_cyto PF07565.13 CDJ57428.1 - 2.4 7.9 9.1 0.31 10.8 2.8 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain AFT PF08731.11 CDJ57428.1 - 2.4 8.6 6.8 0.95 9.9 3.3 1.9 2 0 0 2 2 2 0 Transcription factor AFT DUF4407 PF14362.6 CDJ57428.1 - 2.8 7.2 12.8 4.7 6.5 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1840 PF08895.11 CDJ57428.1 - 3 8.2 8.6 0.98 9.8 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) UPF0560 PF10577.9 CDJ57428.1 - 7.7 4.9 15.6 2.5 6.5 0.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Hydrolase PF00702.26 CDJ57429.1 - 2.6e-06 27.9 30.9 7.4e-05 23.1 2.6 5.8 4 1 0 5 5 5 3 haloacid dehalogenase-like hydrolase Spt20 PF12090.8 CDJ57429.1 - 0.061 12.9 0.2 0.061 12.9 0.2 6.4 5 1 1 6 6 6 0 Spt20 family Utp14 PF04615.13 CDJ57429.1 - 3.1 6.3 40.2 0.076 11.6 14.0 3.4 3 0 0 3 3 3 0 Utp14 protein PI3_PI4_kinase PF00454.27 CDJ57430.1 - 1.7e-17 64.1 0.0 3.1e-15 56.7 0.0 2.7 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDJ57430.1 - 1.7e-06 27.7 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 FATC domain Sox17_18_mid PF12067.8 CDJ57430.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Sox 17/18 central domain DUF4175 PF13779.6 CDJ57432.1 - 0.082 10.8 18.2 0.13 10.2 18.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) Nop14 PF04147.12 CDJ57432.1 - 3.4 5.7 34.6 4.6 5.3 34.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1769 PF08588.10 CDJ57433.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Utp12 PF04003.12 CDJ57434.1 - 4.6e-08 33.3 4.6 1.1e-07 32.1 4.6 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family PARG_cat PF05028.14 CDJ57435.1 - 2.4e-85 286.8 0.0 3.4e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1645 PF07816.11 CDJ57436.1 - 0.002 18.7 24.8 0.002 18.7 24.8 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ57437.1 - 0.00097 18.8 43.2 0.0012 18.5 14.9 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ57437.1 - 0.0011 18.0 31.9 0.019 13.9 11.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ57437.1 - 0.0023 18.0 38.8 0.022 14.8 16.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ57437.1 - 0.8 10.1 14.4 0.66 10.3 4.7 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CDJ57437.1 - 1.4 8.9 6.8 1.3 9.1 0.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SRP9-21 PF05486.12 CDJ57437.1 - 1.6 9.2 8.7 0.44 11.0 1.3 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) AUX_IAA PF02309.16 CDJ57437.1 - 1.9 8.3 5.9 1.6 8.6 0.6 2.1 2 0 0 2 2 2 0 AUX/IAA family PTPRCAP PF15713.5 CDJ57437.1 - 2.3 8.5 20.6 6.3 7.1 14.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_S49_N PF08496.10 CDJ57437.1 - 2.5 8.1 12.0 0.45 10.6 2.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.14 CDJ57437.1 - 3.9 7.4 22.1 0.9 9.5 5.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CDK2AP PF09806.9 CDJ57437.1 - 4.5 7.3 27.9 3 7.8 18.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Band_3_cyto PF07565.13 CDJ57437.1 - 8.3 6.1 14.2 6.8 6.4 6.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4770 PF15994.5 CDJ57437.1 - 9.6 6.4 18.8 5 7.3 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EF-hand_6 PF13405.6 CDJ57439.1 - 7.3e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CDJ57439.1 - 5.3e-06 25.6 0.0 7.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDJ57439.1 - 0.00016 22.1 0.1 0.00021 21.7 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDJ57439.1 - 0.0027 17.1 0.1 0.0044 16.5 0.1 1.3 1 0 0 1 1 1 1 EF hand Caleosin PF05042.13 CDJ57439.1 - 0.0049 16.8 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Caleosin related protein Pex14_N PF04695.13 CDJ57439.1 - 0.18 12.5 8.8 1.9 9.1 5.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF719 PF05334.13 CDJ57439.1 - 0.28 11.4 6.0 0.18 12.0 4.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Presenilin PF01080.17 CDJ57439.1 - 0.83 8.3 3.7 0.88 8.3 3.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3955 PF13127.6 CDJ57440.1 - 0.063 13.1 11.2 0.29 11.0 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) RIFIN PF02009.16 CDJ57440.1 - 0.38 10.6 7.3 0.12 12.3 2.1 2.1 2 0 0 2 2 2 0 Rifin DUF5521 PF17659.1 CDJ57440.1 - 4.2 5.1 7.7 6.6 4.4 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Spt20 PF12090.8 CDJ57443.1 - 1.6e-05 24.6 20.8 2.2e-05 24.2 20.8 1.2 1 0 0 1 1 1 1 Spt20 family Med15 PF09606.10 CDJ57443.1 - 0.00018 20.4 14.7 0.00021 20.2 14.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal V_ATPase_I PF01496.19 CDJ57443.1 - 0.00022 19.3 2.1 0.00024 19.2 2.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family EPL1 PF10513.9 CDJ57443.1 - 0.00056 20.3 1.5 0.00067 20.1 1.5 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like SARAF PF06682.12 CDJ57443.1 - 0.00074 19.3 2.5 0.0012 18.6 2.5 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 CDJ57443.1 - 0.00093 19.6 2.7 0.0011 19.4 2.7 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex DDHD PF02862.17 CDJ57443.1 - 0.0013 19.0 0.1 0.0013 18.9 0.1 1.1 1 0 0 1 1 1 1 DDHD domain Suf PF05843.14 CDJ57443.1 - 0.0015 18.6 5.5 0.0018 18.4 5.5 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 CDJ57443.1 - 0.0038 16.1 22.2 0.0054 15.6 22.2 1.3 1 0 0 1 1 1 1 Androgen receptor TFIIA PF03153.13 CDJ57443.1 - 0.0039 17.3 22.4 0.0049 16.9 22.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ57443.1 - 0.0039 17.0 0.9 0.0053 16.5 0.9 1.1 1 0 0 1 1 1 1 Connexin DUF4770 PF15994.5 CDJ57443.1 - 0.0059 16.9 4.7 0.0097 16.2 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) EOS1 PF12326.8 CDJ57443.1 - 0.0084 16.1 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 1 N-glycosylation protein BAF1_ABF1 PF04684.13 CDJ57443.1 - 0.01 14.9 5.2 0.013 14.6 5.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3408 PF11888.8 CDJ57443.1 - 0.011 15.8 6.1 0.021 15.0 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SpoIIP PF07454.11 CDJ57443.1 - 0.019 14.4 6.3 0.024 14.1 6.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PepSY_TM PF03929.16 CDJ57443.1 - 0.024 14.3 3.8 0.036 13.7 3.8 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SID-1_RNA_chan PF13965.6 CDJ57443.1 - 0.031 12.7 0.1 0.038 12.4 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.8 CDJ57443.1 - 0.032 13.0 4.4 0.041 12.7 4.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FHIPEP PF00771.20 CDJ57443.1 - 0.034 12.6 0.8 0.037 12.5 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family Neur_chan_memb PF02932.16 CDJ57443.1 - 0.038 14.1 1.2 0.044 13.8 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ57443.1 - 0.039 12.9 26.2 0.055 12.4 26.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ57443.1 - 0.047 13.7 10.4 0.061 13.4 10.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RskA PF10099.9 CDJ57443.1 - 0.059 13.7 7.1 0.092 13.0 7.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF913 PF06025.12 CDJ57443.1 - 0.089 11.8 1.5 0.11 11.4 1.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.12 CDJ57443.1 - 0.096 12.1 13.1 0.12 11.7 13.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4175 PF13779.6 CDJ57443.1 - 0.097 10.6 20.0 0.13 10.2 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLN3 PF02487.17 CDJ57443.1 - 0.1 11.6 1.4 0.12 11.4 1.4 1.1 1 0 0 1 1 1 0 CLN3 protein Serinc PF03348.15 CDJ57443.1 - 0.11 11.4 0.8 0.14 11.1 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Eapp_C PF10238.9 CDJ57443.1 - 0.12 12.5 9.0 0.17 12.0 9.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4834 PF16118.5 CDJ57443.1 - 0.13 13.2 12.5 0.26 12.3 12.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 CDJ57443.1 - 0.16 10.9 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Bac_luciferase PF00296.20 CDJ57443.1 - 0.16 11.4 2.6 0.21 10.9 2.6 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Presenilin PF01080.17 CDJ57443.1 - 0.16 10.7 8.2 0.2 10.4 8.2 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 CDJ57443.1 - 0.17 10.4 12.0 0.2 10.1 12.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Myco_haema PF05692.12 CDJ57443.1 - 0.17 10.8 3.0 0.24 10.3 3.0 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin Plasmodium_Vir PF05795.11 CDJ57443.1 - 0.19 11.1 1.8 0.22 10.9 1.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YfhO PF09586.10 CDJ57443.1 - 0.19 9.9 0.2 0.24 9.6 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO eIF-3_zeta PF05091.12 CDJ57443.1 - 0.2 10.6 10.8 0.25 10.3 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 CDJ57443.1 - 0.2 11.4 7.2 0.27 11.0 7.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIP5K PF01504.18 CDJ57443.1 - 0.21 10.8 3.1 0.26 10.5 3.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF775 PF05603.12 CDJ57443.1 - 0.22 11.0 7.3 0.29 10.7 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ctr PF04145.15 CDJ57443.1 - 0.24 12.0 0.7 0.42 11.2 0.7 1.5 1 0 0 1 1 1 0 Ctr copper transporter family Pex14_N PF04695.13 CDJ57443.1 - 0.32 11.6 14.4 0.5 11.0 14.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ57443.1 - 0.33 9.2 14.5 0.41 8.9 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 CDJ57443.1 - 0.35 11.1 7.0 0.54 10.4 7.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5327 PF17261.2 CDJ57443.1 - 0.38 11.5 15.9 0.65 10.8 15.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5327) SLC12 PF03522.15 CDJ57443.1 - 0.39 9.7 6.1 0.5 9.3 6.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ57443.1 - 0.4 10.5 8.7 0.54 10.0 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CTU2 PF10288.9 CDJ57443.1 - 0.44 10.8 10.6 0.77 10.0 10.6 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Methyltransf_32 PF13679.6 CDJ57443.1 - 0.58 10.1 9.8 0.88 9.5 9.8 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4820 PF16091.5 CDJ57443.1 - 0.64 9.4 10.7 0.099 12.0 7.1 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4820) Ureide_permease PF07168.11 CDJ57443.1 - 0.67 8.7 2.4 0.87 8.3 2.4 1.1 1 0 0 1 1 1 0 Ureide permease DUF1980 PF09323.10 CDJ57443.1 - 0.75 9.7 5.0 1.1 9.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S49_N PF08496.10 CDJ57443.1 - 0.76 9.8 6.6 0.63 10.1 4.8 1.8 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Orf78 PF06024.12 CDJ57443.1 - 0.79 10.1 3.7 1.4 9.3 3.7 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF2126 PF09899.9 CDJ57443.1 - 0.79 7.7 5.3 0.93 7.5 5.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Folate_carrier PF01770.18 CDJ57443.1 - 1 8.0 2.2 1.2 7.8 2.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier PepSY_TM_like_2 PF16357.5 CDJ57443.1 - 1.1 9.2 2.4 1.6 8.6 2.4 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like EIIBC-GUT_N PF03612.14 CDJ57443.1 - 1.9 8.2 8.7 2.7 7.7 8.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 CDJ57443.1 - 2.2 7.0 4.6 2.7 6.7 4.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 CDJ57443.1 - 2.4 7.0 5.9 3.1 6.6 5.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AIF_C PF14721.6 CDJ57443.1 - 2.8 8.3 7.7 4.4 7.7 7.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hid1 PF12722.7 CDJ57443.1 - 3 5.9 7.5 3.6 5.6 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kei1 PF08552.11 CDJ57443.1 - 3.2 7.6 6.1 4.4 7.1 6.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ndc1_Nup PF09531.10 CDJ57443.1 - 3.2 6.3 7.3 4.8 5.7 7.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Paf1 PF03985.13 CDJ57443.1 - 3.8 6.4 12.7 5.5 5.9 12.7 1.2 1 0 0 1 1 1 0 Paf1 MDM10 PF12519.8 CDJ57443.1 - 3.9 6.2 5.9 5.1 5.8 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SprA-related PF12118.8 CDJ57443.1 - 6.7 5.7 22.9 9.5 5.3 22.9 1.1 1 0 0 1 1 1 0 SprA-related family Sec62 PF03839.16 CDJ57443.1 - 7.9 5.9 6.9 12 5.3 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RED_N PF07808.13 CDJ57443.1 - 9.3 5.7 14.1 15 5.1 14.1 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region SUIM_assoc PF16619.5 CDJ57444.1 - 0.02 15.0 0.8 0.02 15.0 0.8 5.9 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Exonuc_VII_L PF02601.15 CDJ57444.1 - 0.43 10.1 28.0 0.035 13.7 23.5 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit MMR1 PF08505.10 CDJ57444.1 - 0.81 9.9 26.7 0.12 12.6 20.4 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF572 PF04502.13 CDJ57444.1 - 0.83 9.2 19.1 0.1 12.2 14.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) Lin-8 PF03353.15 CDJ57444.1 - 3.7 7.0 30.1 0.96 8.9 23.3 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF908 PF06012.12 CDJ57444.1 - 3.8 6.8 22.6 10 5.4 18.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF4569 PF15133.6 CDJ57444.1 - 6 6.5 26.6 0.77 9.4 20.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) eIF-3_zeta PF05091.12 CDJ57444.1 - 8.1 5.3 25.9 0.4 9.6 18.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Plasmodium_Vir PF05795.11 CDJ57444.1 - 9.9 5.5 8.3 14 5.0 7.7 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Trimer_CC PF08954.11 CDJ57445.1 - 0.00083 18.9 1.2 0.36 10.4 0.2 3.8 3 1 1 4 4 4 1 Trimerisation motif DUF1640 PF07798.11 CDJ57445.1 - 0.00089 19.3 0.6 0.00089 19.3 0.6 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 CDJ57445.1 - 0.0067 16.5 37.6 0.025 14.6 0.0 4.8 2 1 3 5 5 5 2 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.11 CDJ57445.1 - 0.01 15.4 6.8 0.01 15.4 6.8 2.9 1 1 2 3 3 3 0 Allexivirus 40kDa protein IMUP PF15761.5 CDJ57445.1 - 0.016 15.9 23.0 0.04 14.6 6.9 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein NPV_P10 PF05531.12 CDJ57445.1 - 0.032 14.7 16.7 1.2 9.6 1.2 4.4 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 CDJ57445.1 - 0.042 13.2 30.1 0.26 10.6 14.4 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 CDJ57445.1 - 0.049 13.7 13.3 1.2 9.2 0.3 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF2730) HTH_19 PF12844.7 CDJ57445.1 - 0.052 13.6 0.6 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain T3SchapCesA PF11439.8 CDJ57445.1 - 0.22 11.7 6.0 0.33 11.1 1.1 3.4 2 2 3 5 5 5 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.12 CDJ57445.1 - 0.22 11.6 22.5 0.38 10.8 0.9 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF282 PF03380.14 CDJ57445.1 - 0.24 11.4 0.1 0.41 10.6 0.1 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 TMF_TATA_bd PF12325.8 CDJ57445.1 - 0.24 11.6 27.0 1.3 9.2 1.3 3.6 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 CDJ57445.1 - 0.28 11.5 15.3 2.2 8.7 0.1 5.7 3 2 2 6 6 5 0 TSC-22/dip/bun family SR-25 PF10500.9 CDJ57445.1 - 0.3 10.7 37.8 0.43 10.1 16.3 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Plasmid_RAQPRD PF09686.10 CDJ57445.1 - 0.3 11.3 10.3 1.8 8.8 1.3 4.7 2 2 4 6 6 6 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Spc7 PF08317.11 CDJ57445.1 - 0.49 9.2 34.3 1.8 7.4 10.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ApoO PF09769.9 CDJ57445.1 - 0.51 10.3 7.0 5.6 6.9 0.0 3.3 1 1 3 4 4 4 0 Apolipoprotein O IFT57 PF10498.9 CDJ57445.1 - 0.6 9.0 25.1 0.3 10.0 0.9 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 CDJ57445.1 - 1.5 9.6 20.5 0.87 10.3 2.9 4.1 1 1 3 5 5 5 0 Occludin homology domain HIP1_clath_bdg PF16515.5 CDJ57445.1 - 1.5 9.5 35.0 1.1 9.9 6.8 4.1 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Apolipoprotein PF01442.18 CDJ57445.1 - 1.6 8.6 21.1 3.5 7.5 10.9 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3446 PF11928.8 CDJ57445.1 - 2.1 8.7 24.2 5.1 7.5 8.2 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Chorion_2 PF03964.15 CDJ57445.1 - 2.8 8.8 9.0 6.5 7.7 1.3 2.3 2 0 0 2 2 2 0 Chorion family 2 Secretin_N_2 PF07655.13 CDJ57445.1 - 2.9 8.5 22.8 5.2 7.7 7.9 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DASH_Dad1 PF08649.10 CDJ57445.1 - 3 8.1 8.6 2.5 8.4 0.3 4.1 3 1 1 4 4 4 0 DASH complex subunit Dad1 FUSC PF04632.12 CDJ57445.1 - 3.1 6.2 8.0 1.7 7.1 4.8 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tmemb_cc2 PF10267.9 CDJ57445.1 - 3.4 6.7 30.3 2 7.5 19.7 2.3 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Bcr-Abl_Oligo PF09036.10 CDJ57445.1 - 3.8 7.6 9.5 10 6.2 0.4 3.5 2 1 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain HMMR_N PF15905.5 CDJ57445.1 - 4 6.8 35.8 0.099 12.1 4.1 2.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 CDJ57445.1 - 7.7 6.1 32.0 2.3 7.8 5.5 3.9 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease PAM2 PF07145.15 CDJ57446.1 - 0.00026 20.4 2.1 0.00069 19.1 2.1 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RskA PF10099.9 CDJ57446.1 - 0.00087 19.6 0.1 0.00087 19.6 0.1 9.1 2 2 5 7 7 7 2 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.18 CDJ57446.1 - 0.0049 16.6 6.2 16 5.1 0.4 4.4 3 2 0 4 4 4 1 DNA methylase Chorismate_synt PF01264.21 CDJ57448.1 - 1.7e-91 306.4 0.0 5.1e-72 242.3 0.0 2.8 2 1 0 2 2 2 2 Chorismate synthase Ribosomal_60s PF00428.19 CDJ57448.1 - 0.0021 18.6 4.6 0.0021 18.6 4.6 5.1 3 1 1 4 4 4 1 60s Acidic ribosomal protein DUF5538 PF17692.1 CDJ57448.1 - 0.14 12.2 2.2 0.29 11.2 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Med3 PF11593.8 CDJ57448.1 - 7.3 5.7 19.6 1.1 8.4 14.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DnaJ-X PF14308.6 CDJ57449.1 - 1.7e-28 99.5 11.1 1.6e-20 73.5 4.9 2.1 1 1 1 2 2 2 2 X-domain of DnaJ-containing DASH_Spc19 PF08287.11 CDJ57449.1 - 0.015 15.2 1.8 0.027 14.4 1.8 1.4 1 0 0 1 1 1 0 Spc19 HEPN_Apea PF18739.1 CDJ57449.1 - 0.069 13.6 0.1 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Apea-like HEPN Ribosomal_60s PF00428.19 CDJ57449.1 - 0.34 11.5 11.1 0.66 10.6 1.1 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein RskA PF10099.9 CDJ57450.1 - 8.7e-08 32.7 0.0 5.2e-05 23.6 0.0 10.8 2 1 5 7 7 7 4 Anti-sigma-K factor rskA DUF3689 PF12463.8 CDJ57451.1 - 5.2e-09 35.9 18.3 3.7e-06 26.5 0.0 5.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3689) RskA PF10099.9 CDJ57451.1 - 1.2e-05 25.7 11.2 0.00096 19.5 12.5 22.0 9 5 8 19 19 19 6 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ57451.1 - 3.1e-05 23.7 26.6 3.1e-05 23.7 26.6 20.7 16 4 4 20 20 20 6 Nuclear RNA-splicing-associated protein Myc_N PF01056.18 CDJ57451.1 - 0.0022 18.0 11.8 0.0022 18.0 11.8 13.9 9 4 1 11 11 11 1 Myc amino-terminal region Baculo_8kDa PF06096.11 CDJ57451.1 - 0.16 12.1 5.2 1 9.5 2.9 3.6 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein PNISR PF15996.5 CDJ57452.1 - 0.079 13.2 41.9 0.086 13.1 41.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Gti1_Pac2 PF09729.9 CDJ57452.1 - 0.13 12.4 25.8 0.2 11.7 25.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 CDJ57452.1 - 0.14 10.9 40.9 0.16 10.7 40.9 1.0 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 CDJ57452.1 - 0.49 9.1 25.1 0.55 8.9 25.1 1.1 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 CDJ57452.1 - 0.59 9.2 30.3 0.65 9.0 30.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 CDJ57452.1 - 0.65 8.8 21.8 0.69 8.7 21.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CDJ57452.1 - 3.1 6.4 28.3 3.4 6.2 28.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TP53IP5 PF15331.6 CDJ57452.1 - 3.7 7.6 25.6 4.1 7.5 25.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Merozoite_SPAM PF07133.11 CDJ57452.1 - 3.7 7.5 36.6 5.7 6.9 36.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2151 PF10221.9 CDJ57452.1 - 3.9 5.9 21.4 4.1 5.9 21.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Neur_chan_memb PF02932.16 CDJ57452.1 - 5.2 7.1 27.2 6.4 6.8 27.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ57452.1 - 5.4 5.9 21.0 6.1 5.8 21.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF966 PF06136.13 CDJ57452.1 - 8.5 6.0 26.2 9.1 5.9 26.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MDM10 PF12519.8 CDJ57452.1 - 8.9 5.1 31.3 11 4.7 31.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CAC1F_C PF16885.5 CDJ57452.1 - 8.9 5.9 23.4 11 5.5 23.4 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Ufm1 PF03671.14 CDJ57453.1 - 1e-17 64.0 0.1 1e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Exo_endo_phos PF03372.23 CDJ57455.1 - 2.2e-09 37.2 0.1 1.3e-08 34.6 0.1 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Presenilin PF01080.17 CDJ57455.1 - 5.2e-05 22.2 2.1 6.7e-05 21.8 2.1 1.2 1 0 0 1 1 1 1 Presenilin EPL1 PF10513.9 CDJ57455.1 - 0.00066 20.1 2.7 0.00066 20.1 2.7 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like TERB2 PF15101.6 CDJ57455.1 - 0.0021 18.1 8.6 0.0021 18.1 8.6 2.1 2 0 0 2 2 2 1 Telomere-associated protein TERB2 Velvet PF11754.8 CDJ57455.1 - 0.0022 18.0 4.6 0.0029 17.6 4.6 1.3 1 0 0 1 1 1 1 Velvet factor TFIIA PF03153.13 CDJ57455.1 - 0.0035 17.4 36.6 0.0057 16.7 25.1 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 CDJ57455.1 - 0.0068 16.5 5.4 0.0099 16.0 5.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.13 CDJ57455.1 - 0.014 16.0 21.7 0.1 13.3 16.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.10 CDJ57455.1 - 0.037 12.7 32.7 0.014 14.2 20.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tim54 PF11711.8 CDJ57455.1 - 0.072 11.9 6.1 0.027 13.3 3.5 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 CDJ57455.1 - 0.1 12.2 49.7 0.064 12.9 34.4 2.1 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 CDJ57455.1 - 0.12 11.8 11.1 0.051 13.0 7.4 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4571 PF15137.6 CDJ57455.1 - 0.13 11.9 3.2 0.2 11.3 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Ureide_permease PF07168.11 CDJ57455.1 - 0.16 10.7 0.2 0.31 9.8 0.2 1.5 1 0 0 1 1 1 0 Ureide permease XAP5 PF04921.14 CDJ57455.1 - 0.17 11.7 8.1 0.098 12.5 5.0 1.8 2 0 0 2 2 2 0 XAP5, circadian clock regulator SID-1_RNA_chan PF13965.6 CDJ57455.1 - 0.18 10.2 1.5 0.23 9.8 1.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ57455.1 - 0.23 10.6 3.2 0.091 12.0 1.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4834 PF16118.5 CDJ57455.1 - 0.26 12.3 17.9 0.68 10.9 13.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Fer4_18 PF13746.6 CDJ57455.1 - 0.34 11.1 6.0 0.46 10.7 1.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain EFTUD2 PF16004.5 CDJ57455.1 - 0.63 10.6 13.5 0.21 12.2 8.6 2.0 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus RskA PF10099.9 CDJ57455.1 - 0.64 10.3 17.1 1.8 8.9 1.5 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Connexin PF00029.19 CDJ57455.1 - 0.65 9.7 9.8 0.22 11.2 6.4 1.8 2 0 0 2 2 2 0 Connexin Bul1_N PF04425.12 CDJ57455.1 - 0.89 8.2 10.1 0.077 11.7 5.3 1.5 2 0 0 2 2 2 0 Bul1 N terminus Suf PF05843.14 CDJ57455.1 - 0.89 9.5 16.2 0.43 10.5 10.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3371 PF11851.8 CDJ57455.1 - 0.91 10.6 18.6 3.6 8.7 12.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF4770 PF15994.5 CDJ57455.1 - 0.95 9.7 16.8 0.16 12.2 11.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF775 PF05603.12 CDJ57455.1 - 1.4 8.4 16.5 1.4 8.4 13.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) FAM176 PF14851.6 CDJ57455.1 - 1.6 8.3 6.9 0.87 9.2 4.0 1.9 2 0 0 2 2 2 0 FAM176 family Hydin_ADK PF17213.3 CDJ57455.1 - 1.7 8.8 10.9 8.2 6.6 7.5 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain TMEM51 PF15345.6 CDJ57455.1 - 1.9 8.3 18.2 0.065 13.1 10.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 Peroxin-13_N PF04088.13 CDJ57455.1 - 1.9 8.7 7.8 6.8 7.0 6.2 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2232 PF09991.9 CDJ57455.1 - 2 7.5 3.4 0.9 8.7 0.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) FHIPEP PF00771.20 CDJ57455.1 - 2 6.8 7.6 0.23 9.9 2.8 1.7 2 0 0 2 2 2 0 FHIPEP family Rxt3 PF08642.10 CDJ57455.1 - 2.1 9.1 10.2 2.4 9.0 6.1 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 BBS2_C PF14782.6 CDJ57455.1 - 2.5 6.8 14.2 0.073 11.8 6.4 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal RR_TM4-6 PF06459.12 CDJ57455.1 - 2.6 7.8 11.7 2.2 8.0 9.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ57455.1 - 2.8 8.0 16.5 11 6.1 16.5 1.8 1 1 0 1 1 1 0 DDHD domain FAM60A PF15396.6 CDJ57455.1 - 2.9 7.9 8.2 6.1 6.8 7.3 1.7 2 0 0 2 2 2 0 Protein Family FAM60A PAT1 PF09770.9 CDJ57455.1 - 3 6.0 26.7 0.23 9.7 17.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.8 CDJ57455.1 - 3.1 6.6 42.0 2.2 7.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) STAC2_u1 PF16664.5 CDJ57455.1 - 4.3 7.8 9.5 6.2 7.3 7.4 2.0 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 UPF0560 PF10577.9 CDJ57455.1 - 5 5.5 22.4 0.15 10.5 14.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Paramyxo_ncap PF00973.19 CDJ57455.1 - 6.4 5.6 6.4 11 4.7 6.4 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4175 PF13779.6 CDJ57455.1 - 6.7 4.5 36.1 0.67 7.8 26.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF3381 PF11861.8 CDJ57455.1 - 6.9 6.4 17.3 2.7 7.8 11.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MDM10 PF12519.8 CDJ57455.1 - 8.1 5.2 10.4 1.3 7.8 6.8 1.4 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 OATP PF03137.20 CDJ57455.1 - 8.7 4.5 7.0 4.9 5.3 4.9 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.15 CDJ57455.1 - 9.4 6.8 11.3 3.7 8.2 7.4 2.0 2 0 0 2 2 2 0 Ctr copper transporter family AAA PF00004.29 CDJ57456.1 - 1.9e-09 38.0 0.1 1.9e-09 38.0 0.1 2.8 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) SUIM_assoc PF16619.5 CDJ57456.1 - 0.068 13.2 0.0 0.068 13.2 0.0 7.7 4 3 3 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 CSG2 PF16965.5 CDJ57456.1 - 0.16 10.8 4.9 0.33 9.8 4.9 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator Peptidase_U57 PF05582.12 CDJ57456.1 - 1 8.6 6.4 11 5.1 0.1 2.4 2 0 0 2 2 2 0 YabG peptidase U57 NUDIX PF00293.28 CDJ57457.1 - 0.015 15.3 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 NUDIX domain Flavodoxin_1 PF00258.25 CDJ57458.1 - 7e-15 55.5 0.1 2.4e-14 53.7 0.0 4.5 4 1 0 4 4 4 2 Flavodoxin SUIM_assoc PF16619.5 CDJ57458.1 - 0.0011 18.9 0.3 0.0011 18.9 0.3 6.1 5 1 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 FAD_binding_1 PF00667.20 CDJ57458.1 - 0.3 10.6 3.0 2.3 7.7 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain Peptidase_C12 PF01088.21 CDJ57459.1 - 3.3e-35 121.8 1.5 8.3e-35 120.4 1.5 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDJ57459.1 - 1.7e-16 59.8 1.3 1.7e-16 59.8 1.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases IMUP PF15761.5 CDJ57459.1 - 1.8 9.3 10.2 5.1 7.8 10.2 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein EccE PF11203.8 CDJ57462.1 - 0.001 19.3 6.5 0.0042 17.4 6.5 2.0 1 0 0 1 1 1 1 Putative type VII ESX secretion system translocon, EccE Peptidase_C97 PF05903.14 CDJ57462.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Presenilin PF01080.17 CDJ57462.1 - 0.83 8.3 13.6 1.4 7.6 13.6 1.4 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ57464.1 - 1.6 8.3 9.9 3.2 7.3 9.9 1.4 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ57464.1 - 2.5 7.0 14.2 5.4 5.9 14.2 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ57465.1 - 0.0046 17.0 34.1 0.0046 17.0 34.1 4.2 4 1 1 5 5 5 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ57465.1 - 2.1 7.2 18.9 5 6.0 18.9 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLU PF13236.6 CDJ57467.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 Clustered mitochondria Fmp27_WPPW PF10359.9 CDJ57467.1 - 0.3 9.9 4.7 0.4 9.5 4.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain LCD1 PF09798.9 CDJ57467.1 - 0.95 7.9 7.7 1.3 7.4 7.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Nsp1_C PF05064.13 CDJ57467.1 - 1.1 9.1 5.9 3.4 7.5 0.7 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0175 PF03683.13 CDJ57469.1 - 0.052 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) AF-4 PF05110.13 CDJ57469.1 - 0.21 9.7 12.9 0.4 8.7 12.9 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PseudoU_synth_1 PF01416.20 CDJ57470.1 - 6.3e-08 33.1 0.0 0.0019 18.6 0.0 3.7 3 1 1 4 4 4 3 tRNA pseudouridine synthase TFIIA PF03153.13 CDJ57471.1 - 0.0051 16.9 15.5 0.011 15.7 15.5 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit WTX PF09422.10 CDJ57471.1 - 0.073 12.1 6.6 0.13 11.3 6.6 1.3 1 0 0 1 1 1 0 WTX protein CDC37_N PF03234.14 CDJ57471.1 - 3 8.8 14.7 1.4e+02 3.4 15.3 3.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Vma12 PF11712.8 CDJ57471.1 - 5.9 7.0 9.5 19 5.3 9.5 1.9 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.25 CDJ57473.1 - 4.5e-21 75.4 0.2 4.5e-21 75.4 0.2 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57473.1 - 5.9e-10 38.9 0.1 5.9e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4614 PF15391.6 CDJ57474.1 - 0.0047 17.0 10.2 0.0047 17.0 10.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4614) CDC45 PF02724.14 CDJ57474.1 - 0.031 12.6 0.1 0.036 12.4 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 CDJ57474.1 - 0.18 10.6 17.2 0.11 11.3 9.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Nop14 PF04147.12 CDJ57474.1 - 0.18 10.0 3.4 0.27 9.4 3.4 1.2 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.19 CDJ57474.1 - 0.31 10.9 21.7 0.66 9.8 11.4 2.1 2 0 0 2 2 2 0 SPX domain Ecl1 PF12855.7 CDJ57474.1 - 3.6 8.7 33.0 0.49 11.5 6.5 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins SOBP PF15279.6 CDJ57474.1 - 7.2 7.1 11.3 6.4 7.3 4.7 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein MTHFR_C PF12225.8 CDJ57475.1 - 0.017 14.8 0.3 0.059 13.0 0.3 1.9 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal DUF812 PF05667.11 CDJ57475.1 - 7.1 5.4 34.0 1.4 7.7 20.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) RskA PF10099.9 CDJ57476.1 - 0.00029 21.2 9.8 0.00029 21.2 9.8 6.2 1 1 4 5 5 5 2 Anti-sigma-K factor rskA RPA43_OB PF17875.1 CDJ57476.1 - 7.8 7.1 29.8 0.5 11.0 1.1 4.3 4 0 0 4 4 4 0 RPA43 OB domain in RNA Pol I TraT PF05818.12 CDJ57477.1 - 0.038 13.7 0.1 0.038 13.7 0.1 1.7 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF3138 PF11336.8 CDJ57477.1 - 0.17 10.5 10.0 0.28 9.8 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3275 PF11679.8 CDJ57477.1 - 0.21 11.5 2.9 0.45 10.5 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TPR_6 PF13174.6 CDJ57477.1 - 1.5 9.7 0.0 1.5 9.7 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Plant_vir_prot PF01307.17 CDJ57478.1 - 0.21 11.8 2.3 0.61 10.3 2.3 1.8 1 0 0 1 1 1 0 Plant viral movement protein DUF4407 PF14362.6 CDJ57478.1 - 4 6.7 17.8 6.5 6.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 CDJ57479.1 - 0.00028 20.0 12.5 0.00028 20.0 12.5 4.1 3 1 0 4 4 4 2 Transcriptional activator LAG-3 Otopetrin PF03189.13 CDJ57479.1 - 0.058 12.2 0.0 0.058 12.2 0.0 4.1 3 1 0 3 3 3 0 Otopetrin DUF5040 PF16443.5 CDJ57480.1 - 0.0021 17.5 0.7 0.37 10.1 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF5040) TFIIA PF03153.13 CDJ57480.1 - 0.028 14.4 16.5 0.033 14.2 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAS20 PF02064.15 CDJ57480.1 - 0.04 14.0 10.3 0.062 13.4 10.3 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Exonuc_VII_L PF02601.15 CDJ57480.1 - 0.067 12.8 5.8 0.074 12.6 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PEX11 PF05648.14 CDJ57480.1 - 0.13 11.7 4.6 7.8 5.9 4.2 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Cid2 PF09774.9 CDJ57480.1 - 0.37 11.2 10.0 6.5 7.2 11.1 2.0 2 0 0 2 2 2 0 Caffeine-induced death protein 2 ASC PF00858.24 CDJ57480.1 - 0.38 9.7 3.1 0.5 9.3 3.1 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel OATP PF03137.20 CDJ57480.1 - 0.4 8.9 1.2 0.42 8.8 1.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 CDJ57480.1 - 0.99 8.1 5.1 1.2 7.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF2877 PF11392.8 CDJ57480.1 - 1.1 10.0 3.5 5.8 7.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF4490 PF14892.6 CDJ57480.1 - 2.3 8.3 10.5 4.4 7.4 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) CLN3 PF02487.17 CDJ57480.1 - 5.8 5.8 6.3 8.2 5.4 6.3 1.2 1 0 0 1 1 1 0 CLN3 protein Spore_YhcN_YlaJ PF09580.10 CDJ57480.1 - 5.9 7.0 12.7 14 5.7 12.7 1.5 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BRCT_2 PF16589.5 CDJ57481.1 - 1.2e-06 28.9 0.0 3.5e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Pescadillo_N PF06732.11 CDJ57481.1 - 8.2e-06 25.5 0.1 8.2e-06 25.5 0.1 2.6 2 1 0 2 2 2 1 Pescadillo N-terminus MS_channel PF00924.18 CDJ57483.1 - 5.6e-12 45.6 1.6 9.5e-12 44.9 1.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel RtcB PF01139.17 CDJ57484.1 - 2.1e-44 152.3 0.0 2.4e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB IMUP PF15761.5 CDJ57485.1 - 0.74 10.5 9.8 2.6 8.8 0.5 3.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ57486.1 - 0.1 11.3 37.7 0.11 11.2 37.7 1.0 1 0 0 1 1 1 0 Presenilin TCP PF03634.13 CDJ57486.1 - 0.52 10.8 28.5 0.63 10.6 28.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor RNA_pol_Rbc25 PF08292.12 CDJ57486.1 - 2.2 8.5 20.8 3.4 7.9 20.8 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 RR_TM4-6 PF06459.12 CDJ57486.1 - 2.3 8.0 30.2 2.6 7.8 30.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ57486.1 - 3.7 6.5 31.8 4.2 6.3 31.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SelP_N PF04592.14 CDJ57486.1 - 3.9 6.8 32.0 4.9 6.5 32.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.14 CDJ57486.1 - 4.8 5.4 25.3 5.7 5.1 25.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 CDJ57486.1 - 5.9 5.3 25.9 7.4 5.0 25.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4045 PF13254.6 CDJ57486.1 - 7.3 6.1 25.9 8.6 5.9 25.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Band_3_cyto PF07565.13 CDJ57486.1 - 8.1 6.2 30.2 12 5.6 30.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ57486.1 - 9.7 6.1 26.2 12 5.8 26.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Yip1 PF04893.17 CDJ57487.1 - 3.6e-05 23.5 0.7 6.2e-05 22.8 0.7 1.3 1 0 0 1 1 1 1 Yip1 domain Phasin PF05597.11 CDJ57488.1 - 0.022 14.8 7.1 0.031 14.3 7.1 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ImcF-related_N PF14331.6 CDJ57488.1 - 0.025 13.9 3.2 0.029 13.7 3.2 1.0 1 0 0 1 1 1 0 ImcF-related N-terminal domain Y1_Tnp PF01797.16 CDJ57488.1 - 0.067 13.3 0.1 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 Transposase IS200 like DUF4559 PF15112.6 CDJ57488.1 - 0.072 12.8 7.4 0.088 12.5 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Fmp27_WPPW PF10359.9 CDJ57488.1 - 0.11 11.3 6.6 0.12 11.2 6.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FeoB_Cyto PF17910.1 CDJ57488.1 - 0.17 12.5 4.7 0.13 12.8 3.0 1.7 1 1 1 2 2 2 0 FeoB cytosolic helical domain DUF2076 PF09849.9 CDJ57488.1 - 0.19 11.8 8.1 0.28 11.2 8.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NPV_P10 PF05531.12 CDJ57488.1 - 0.28 11.7 10.3 0.25 11.8 2.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 CDJ57488.1 - 0.31 10.6 8.9 0.41 10.2 8.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_L PF02601.15 CDJ57488.1 - 0.49 9.9 6.1 0.58 9.7 6.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ57488.1 - 0.89 8.9 6.0 0.98 8.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 CDJ57488.1 - 2.9 7.1 6.9 3.3 6.9 6.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Myb_DNA-binding PF00249.31 CDJ57489.1 - 6.3e-10 39.1 0.0 9.1e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ57489.1 - 7.2e-06 26.2 0.0 3.2e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain FidL_like PF15941.5 CDJ57490.1 - 0.12 12.9 4.5 0.2 12.1 0.3 2.4 2 0 0 2 2 2 0 FidL-like putative membrane protein FLYWCH PF04500.16 CDJ57490.1 - 2 8.6 10.6 1.5 9.0 1.0 3.6 3 0 0 3 3 3 0 FLYWCH zinc finger domain Dehydrin PF00257.19 CDJ57490.1 - 9.3 6.8 13.3 6.7 7.2 3.6 2.6 1 1 1 2 2 2 0 Dehydrin Pkinase PF00069.25 CDJ57491.1 - 1.8e-50 171.8 1.9 3.3e-22 79.1 0.0 4.8 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57491.1 - 6.3e-33 114.2 0.0 1.4e-17 63.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase HA2 PF04408.23 CDJ57492.1 - 7.8e-26 90.5 0.0 2.2e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ57492.1 - 2.4e-22 79.1 0.0 4.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ57492.1 - 6.4e-10 39.4 0.0 1.6e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CDJ57492.1 - 3e-08 33.9 0.0 7.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CDJ57492.1 - 0.00024 21.4 0.0 0.00075 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDJ57492.1 - 0.00028 20.7 0.0 0.0009 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ57492.1 - 0.0016 18.3 0.4 0.013 15.2 0.2 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDJ57492.1 - 0.0089 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CDJ57492.1 - 0.0098 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ57492.1 - 0.023 13.8 0.2 0.046 12.8 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 CDJ57492.1 - 0.039 13.4 0.4 0.19 11.1 0.2 2.1 2 0 0 2 2 2 0 PhoH-like protein Microtub_bd PF16796.5 CDJ57492.1 - 0.11 12.4 0.0 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_16 PF13191.6 CDJ57492.1 - 1.7 9.0 5.9 0.41 11.0 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain SUI1 PF01253.22 CDJ57493.1 - 4.6e-27 94.4 0.4 5.7e-27 94.1 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 CDJ57493.1 - 0.067 13.5 0.1 0.1 12.9 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RNase_PH PF01138.21 CDJ57494.1 - 1.2e-09 38.8 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SpoIIP PF07454.11 CDJ57495.1 - 7 6.0 19.0 0.15 11.5 7.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EAGR_box PF16713.5 CDJ57496.1 - 0.0045 16.6 5.3 0.0045 16.6 5.3 4.9 5 0 0 5 5 5 4 Enriched in aromatic and glycine Residues box CNDH2_C PF16858.5 CDJ57497.1 - 0.033 14.1 7.7 0.025 14.5 6.3 1.5 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ferlin_C PF16165.5 CDJ57497.1 - 0.16 11.9 0.7 0.31 11.0 0.7 1.5 1 0 0 1 1 1 0 Ferlin C-terminus DUF4407 PF14362.6 CDJ57497.1 - 4.1 6.7 24.8 0.021 14.2 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S64 PF08192.11 CDJ57497.1 - 8.1 4.8 16.5 11 4.4 16.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.13 CDJ57498.1 - 0.023 14.7 49.2 0.095 12.7 14.7 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ57498.1 - 0.91 9.1 42.8 0.28 10.8 19.6 2.7 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ57498.1 - 6.8 5.5 26.3 0.14 11.1 10.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Mit_KHE1 PF10173.9 CDJ57500.1 - 0.45 10.6 4.3 10 6.1 0.2 2.8 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Rsc14 PF08586.10 CDJ57500.1 - 0.67 10.8 9.6 0.44 11.4 1.7 3.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit AT_hook PF02178.19 CDJ57500.1 - 1 9.4 7.2 2.9 8.1 7.2 1.8 1 0 0 1 1 1 0 AT hook motif Peptidase_S49_N PF08496.10 CDJ57500.1 - 3.4 7.7 14.8 0.44 10.6 2.4 2.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF572 PF04502.13 CDJ57501.1 - 0.03 14.0 27.1 0.51 9.9 20.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DDHD PF02862.17 CDJ57501.1 - 0.33 11.1 26.2 2.3 8.3 19.0 2.3 2 0 0 2 2 2 0 DDHD domain Peptidase_M15_2 PF05951.13 CDJ57501.1 - 0.8 9.4 6.4 1.4 8.6 6.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) RR_TM4-6 PF06459.12 CDJ57501.1 - 4.5 7.0 29.3 1 9.2 17.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MAT1 PF06391.13 CDJ57501.1 - 5.1 6.9 41.4 6.3 6.6 31.7 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RIFIN PF02009.16 CDJ57501.1 - 6.6 6.5 23.0 3.1 7.6 16.3 2.4 2 0 0 2 2 2 0 Rifin Neur_chan_memb PF02932.16 CDJ57501.1 - 7.7 6.5 24.5 12 5.8 1.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 CDJ57501.1 - 8.5 5.7 26.4 3.6 6.9 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Spore_III_AF PF09581.10 CDJ57502.1 - 0.012 15.7 9.4 0.51 10.3 1.6 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF4834 PF16118.5 CDJ57502.1 - 0.025 15.5 5.0 0.025 15.5 5.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Lin-8 PF03353.15 CDJ57502.1 - 0.15 11.6 22.3 0.84 9.1 9.4 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CDJ57502.1 - 0.26 10.9 14.4 0.13 11.9 1.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4820 PF16091.5 CDJ57502.1 - 1.1 8.6 13.8 0.14 11.5 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Band_3_cyto PF07565.13 CDJ57502.1 - 1.3 8.8 10.7 1.3 8.7 2.5 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Eapp_C PF10238.9 CDJ57502.1 - 1.8 8.6 12.5 0.21 11.7 3.5 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3381 PF11861.8 CDJ57502.1 - 2.5 7.9 24.1 0.87 9.4 11.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Activator_LAG-3 PF11498.8 CDJ57502.1 - 3.2 6.6 40.7 0.018 14.1 6.7 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SpoIIP PF07454.11 CDJ57502.1 - 4.9 6.5 14.2 0.46 9.9 6.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 CDJ57502.1 - 7.3 6.7 24.0 0.54 10.3 9.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UPF0560 PF10577.9 CDJ57502.1 - 9.3 4.6 20.3 4.1 5.8 9.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF1645 PF07816.11 CDJ57502.1 - 9.6 6.7 28.0 0.076 13.6 7.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) FAM60A PF15396.6 CDJ57502.1 - 9.8 6.1 12.1 5.6 6.9 1.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF2465 PF10239.9 CDJ57503.1 - 3.1e-06 26.7 0.3 9.4e-06 25.1 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) SUIM_assoc PF16619.5 CDJ57503.1 - 0.017 15.2 10.3 0.59 10.2 1.2 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ57503.1 - 0.52 9.9 9.4 5.8 6.4 4.0 2.5 3 0 0 3 3 3 0 Spt20 family Ribosomal_60s PF00428.19 CDJ57503.1 - 2.9 8.5 15.8 2.1 9.0 9.6 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DcpS_C PF11969.8 CDJ57504.1 - 3.4e-07 30.7 0.1 1.3e-06 28.9 0.1 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Tim54 PF11711.8 CDJ57504.1 - 0.028 13.2 1.1 0.079 11.7 0.2 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF915 PF06028.11 CDJ57505.1 - 0.18 11.1 6.6 0.26 10.6 6.6 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Utp14 PF04615.13 CDJ57505.1 - 0.64 8.5 26.5 0.84 8.1 26.5 1.2 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 CDJ57505.1 - 0.98 7.9 20.7 1.2 7.6 20.7 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDJ57505.1 - 3.1 7.3 15.2 5.1 6.6 15.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.6 CDJ57505.1 - 6.7 5.4 17.8 9.7 4.9 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 CDJ57505.1 - 8.4 6.2 25.1 13 5.6 25.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BOP1NT PF08145.12 CDJ57506.1 - 1.9e-25 90.2 8.5 4.7e-19 69.3 0.6 4.0 3 1 1 4 4 4 2 BOP1NT (NUC169) domain WD40 PF00400.32 CDJ57506.1 - 4.4e-13 49.5 0.1 0.0004 21.1 0.1 5.8 6 0 0 6 6 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57506.1 - 2.1e-06 27.9 0.0 2.2 8.6 0.0 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SR-25 PF10500.9 CDJ57506.1 - 0.0051 16.5 32.9 0.0057 16.3 5.9 3.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Velvet PF11754.8 CDJ57506.1 - 0.0065 16.4 0.9 0.0065 16.4 0.9 2.7 2 1 0 2 2 1 1 Velvet factor Mcl1_mid PF12341.8 CDJ57506.1 - 0.043 13.2 0.2 0.2 11.0 0.0 2.2 2 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region RNase_H2_suC PF08615.11 CDJ57506.1 - 0.061 13.5 2.1 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PEPCK_ATP PF01293.20 CDJ57506.1 - 0.17 10.6 1.1 0.25 10.0 1.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Activator_LAG-3 PF11498.8 CDJ57506.1 - 0.2 10.6 32.7 0.094 11.7 9.8 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ57506.1 - 0.33 10.5 39.1 1.1 8.8 10.9 2.5 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ57506.1 - 0.47 9.5 23.9 0.39 9.8 14.9 2.4 2 0 0 2 2 2 0 Drosophila roughex protein CCSAP PF15748.5 CDJ57506.1 - 0.6 10.2 32.2 0.46 10.6 3.2 2.6 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RAB3GAP2_N PF14655.6 CDJ57506.1 - 1.6 7.9 12.4 8.4 5.5 2.1 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TERB2 PF15101.6 CDJ57506.1 - 1.7 8.6 20.9 2.8 7.9 10.0 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SUIM_assoc PF16619.5 CDJ57506.1 - 2.3 8.4 37.7 0.76 9.9 14.0 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Eapp_C PF10238.9 CDJ57506.1 - 2.8 8.0 15.0 11 6.0 0.8 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein Suf PF05843.14 CDJ57506.1 - 3 7.8 24.1 0.26 11.2 2.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CDJ57506.1 - 3.8 7.6 21.9 0.031 14.5 1.5 2.9 3 1 0 3 3 3 0 DDHD domain DUF2722 PF10846.8 CDJ57506.1 - 4 6.3 36.3 0.068 12.1 3.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ57506.1 - 6.2 5.5 26.0 3.2 6.4 3.6 2.3 2 0 0 2 2 2 0 Presenilin Band_3_cyto PF07565.13 CDJ57506.1 - 8.8 6.0 15.6 7 6.4 6.3 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ57506.1 - 9.6 6.1 17.4 14 5.6 8.5 2.5 2 0 0 2 2 2 0 Protein Family FAM60A RskA PF10099.9 CDJ57507.1 - 0.0023 18.2 1.7 0.0023 18.2 1.7 2.9 2 1 0 3 3 3 1 Anti-sigma-K factor rskA Zn_peptidase PF04228.13 CDJ57507.1 - 0.012 15.1 1.8 0.021 14.3 1.8 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2722 PF10846.8 CDJ57507.1 - 0.078 11.9 17.8 0.027 13.4 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RNase_H2_suC PF08615.11 CDJ57507.1 - 0.095 12.9 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4834 PF16118.5 CDJ57507.1 - 0.2 12.6 0.3 0.2 12.6 0.3 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ57507.1 - 0.38 9.5 2.6 0.58 8.9 2.6 1.2 1 0 0 1 1 1 0 Presenilin Spore_YhcN_YlaJ PF09580.10 CDJ57507.1 - 0.58 10.2 4.2 1 9.5 4.2 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BRF1 PF07741.13 CDJ57507.1 - 1.6 9.1 5.1 10 6.6 0.2 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF4050 PF13259.6 CDJ57507.1 - 1.9 8.8 6.4 0.28 11.5 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4050) TFIIA PF03153.13 CDJ57507.1 - 3.2 7.7 29.8 10 6.0 29.9 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ57507.1 - 6.3 7.7 30.8 1.3 9.9 9.3 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Nop16 PF09420.10 CDJ57508.1 - 2.2e-11 44.2 2.1 2.2e-11 44.2 2.1 3.3 2 2 1 3 3 3 1 Ribosome biogenesis protein Nop16 DUF572 PF04502.13 CDJ57508.1 - 0.34 10.5 26.6 0.43 10.1 26.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RRM_1 PF00076.22 CDJ57509.1 - 7e-35 118.7 0.5 4.3e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ57509.1 - 8.4e-11 41.9 0.1 0.00045 20.3 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ57509.1 - 1.9e-05 24.6 0.1 0.054 13.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 CDJ57509.1 - 0.00069 19.7 11.3 0.00086 19.4 11.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRM_3 PF08777.11 CDJ57509.1 - 0.00081 19.4 5.5 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif DUF4698 PF15769.5 CDJ57509.1 - 0.11 11.5 1.4 0.19 10.7 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Hydin_ADK PF17213.3 CDJ57509.1 - 0.23 11.7 4.7 0.4 10.9 4.7 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2722 PF10846.8 CDJ57509.1 - 4.1 6.2 15.2 0.011 14.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.12 CDJ57510.1 - 0.0031 17.3 10.3 0.0043 16.8 10.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Slu7 PF11708.8 CDJ57510.1 - 0.0037 17.1 5.7 0.0047 16.7 5.7 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor DUF4770 PF15994.5 CDJ57510.1 - 0.0038 17.5 7.1 0.0046 17.2 7.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) TFIIA PF03153.13 CDJ57510.1 - 0.0049 16.9 20.6 0.0064 16.5 20.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ57510.1 - 0.0093 14.7 14.9 0.0092 14.7 14.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.15 CDJ57510.1 - 0.0098 15.5 13.3 0.012 15.2 13.3 1.0 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist FCP1_C PF09309.10 CDJ57510.1 - 0.011 15.6 12.0 0.014 15.3 12.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF1645 PF07816.11 CDJ57510.1 - 0.015 15.9 12.5 0.02 15.5 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF4366 PF14283.6 CDJ57510.1 - 0.018 15.1 2.9 0.12 12.4 2.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 CDJ57510.1 - 0.019 14.4 5.9 0.022 14.2 5.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S49_N PF08496.10 CDJ57510.1 - 0.029 14.4 5.7 0.041 13.9 5.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MecA PF05389.12 CDJ57510.1 - 0.038 13.6 9.7 0.029 14.0 8.5 1.3 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) Roughex PF06020.11 CDJ57510.1 - 0.038 13.1 10.5 0.043 12.9 10.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 CDJ57510.1 - 0.044 12.8 4.4 0.055 12.4 4.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 CDJ57510.1 - 0.053 10.6 11.5 0.059 10.5 11.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 CDJ57510.1 - 0.054 11.4 5.4 0.057 11.3 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0524 PF15823.5 CDJ57510.1 - 0.094 12.1 7.7 0.11 11.8 7.7 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 Consortin_C PF15281.6 CDJ57510.1 - 0.097 12.7 0.3 0.21 11.6 0.2 1.5 1 1 1 2 2 2 0 Consortin C-terminus RED_N PF07808.13 CDJ57510.1 - 0.1 12.1 9.3 0.14 11.7 9.3 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF1676 PF07898.13 CDJ57510.1 - 0.13 12.3 1.8 0.17 12.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Gti1_Pac2 PF09729.9 CDJ57510.1 - 0.13 12.3 8.8 0.19 11.8 8.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 CDJ57510.1 - 0.14 10.9 10.6 0.66 8.7 8.5 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PI3K_1B_p101 PF10486.9 CDJ57510.1 - 0.2 9.4 11.7 0.24 9.1 11.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MMM1 PF10296.9 CDJ57510.1 - 0.21 10.6 7.3 0.14 11.2 6.1 1.3 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Inhibitor_I69 PF13734.6 CDJ57510.1 - 0.24 11.8 9.3 0.58 10.6 5.2 2.1 2 0 0 2 2 2 0 Spi protease inhibitor MMR1 PF08505.10 CDJ57510.1 - 0.28 11.4 16.8 0.36 11.1 16.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4598 PF15370.6 CDJ57510.1 - 0.29 11.6 10.1 1.7 9.2 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Otopetrin PF03189.13 CDJ57510.1 - 0.29 9.9 2.8 0.35 9.6 2.8 1.1 1 0 0 1 1 1 0 Otopetrin Ndc1_Nup PF09531.10 CDJ57510.1 - 0.3 9.7 13.5 0.34 9.5 13.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 CDJ57510.1 - 0.31 10.6 12.1 0.4 10.3 12.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PepSY_TM PF03929.16 CDJ57510.1 - 0.32 10.6 1.1 0.31 10.7 1.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CDJ57510.1 - 0.34 9.6 14.4 0.43 9.3 14.4 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ57510.1 - 0.42 9.4 15.1 0.49 9.2 15.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ57510.1 - 0.51 8.8 16.0 0.62 8.6 16.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF3504 PF12012.8 CDJ57510.1 - 0.55 10.1 7.5 0.62 9.9 7.1 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) FHIPEP PF00771.20 CDJ57510.1 - 0.64 8.4 4.8 0.81 8.1 4.8 1.2 1 0 0 1 1 1 0 FHIPEP family Peptidase_S64 PF08192.11 CDJ57510.1 - 0.69 8.3 13.7 0.82 8.1 13.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 SLC12 PF03522.15 CDJ57510.1 - 0.74 8.8 10.1 0.79 8.7 10.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Miga PF10265.9 CDJ57510.1 - 0.74 8.7 10.6 0.88 8.5 10.6 1.0 1 0 0 1 1 1 0 Mitoguardin Orf78 PF06024.12 CDJ57510.1 - 0.77 10.1 9.9 15 6.0 8.2 2.1 1 1 1 2 2 2 0 Orf78 (ac78) ALMT PF11744.8 CDJ57510.1 - 0.85 8.4 7.7 0.92 8.3 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter EMC3_TMCO1 PF01956.16 CDJ57510.1 - 0.85 9.3 5.0 0.98 9.1 5.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FAM220 PF15487.6 CDJ57510.1 - 0.9 9.1 12.3 1.1 8.8 12.3 1.1 1 0 0 1 1 1 0 FAM220 family DUF3464 PF11947.8 CDJ57510.1 - 0.96 9.2 11.0 0.4 10.4 8.0 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 NARP1 PF12569.8 CDJ57510.1 - 1 8.2 10.9 1.5 7.6 10.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med26_C PF15693.5 CDJ57510.1 - 1.1 9.4 12.6 1.3 9.1 12.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal SPX PF03105.19 CDJ57510.1 - 1.2 9.0 16.0 1.4 8.7 16.0 1.1 1 0 0 1 1 1 0 SPX domain DDRGK PF09756.9 CDJ57510.1 - 1.8 8.1 17.0 2.7 7.6 17.0 1.1 1 0 0 1 1 1 0 DDRGK domain Membralin PF09746.9 CDJ57510.1 - 1.9 7.4 5.2 2.2 7.2 5.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein MDM31_MDM32 PF08118.11 CDJ57510.1 - 2.8 6.5 7.3 3.2 6.3 6.9 1.3 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins TOM13 PF08219.11 CDJ57510.1 - 3.7 7.6 5.0 4.2 7.4 1.5 2.2 2 0 0 2 2 2 0 Outer membrane protein TOM13 FTO_NTD PF12933.7 CDJ57510.1 - 3.8 6.7 10.9 5 6.3 10.9 1.3 1 1 0 1 1 1 0 FTO catalytic domain RNA_pol_Rbc25 PF08292.12 CDJ57510.1 - 4 7.7 9.3 2.3 8.5 7.0 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 DUF4175 PF13779.6 CDJ57510.1 - 4.2 5.1 21.5 5.1 4.9 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MscS_TM PF12794.7 CDJ57510.1 - 4.9 5.9 9.8 5.2 5.8 8.9 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4199 PF13858.6 CDJ57510.1 - 5 7.5 6.7 6.2 7.2 6.1 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4199) PigN PF04987.14 CDJ57510.1 - 5.4 5.8 7.2 12 4.6 6.6 1.7 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Neur_chan_memb PF02932.16 CDJ57510.1 - 5.8 6.9 11.0 7.5 6.5 11.0 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRF1 PF10380.9 CDJ57510.1 - 7.1 7.0 11.1 1 9.7 6.6 1.7 2 0 0 2 2 2 0 Transcription factor CRF1 Peroxin-13_N PF04088.13 CDJ57510.1 - 7.1 6.9 11.4 31 4.8 9.8 2.0 1 1 1 2 2 2 0 Peroxin 13, N-terminal region Suf PF05843.14 CDJ57510.1 - 7.5 6.4 20.8 2.4 8.0 18.0 1.5 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) PcfK PF14058.6 CDJ57510.1 - 9.7 6.5 17.9 16 5.8 17.9 1.3 1 0 0 1 1 1 0 PcfK-like protein Peptidase_M1 PF01433.20 CDJ57511.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ57511.1 - 2.3e-11 44.0 0.1 2.3e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M61 PF05299.12 CDJ57511.1 - 0.00021 21.6 0.1 0.0074 16.7 0.1 2.6 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M1_N PF17900.1 CDJ57511.1 - 0.00023 21.4 0.0 0.00065 19.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain RXLR PF16810.5 CDJ57511.1 - 0.025 15.0 0.8 0.19 12.1 0.2 2.3 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity RrnaAD PF00398.20 CDJ57512.1 - 1.8e-15 56.7 0.0 3.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TFIIA PF03153.13 CDJ57512.1 - 0.0017 18.5 29.5 0.0017 18.5 29.5 6.1 4 1 2 6 6 6 1 Transcription factor IIA, alpha/beta subunit UvrD-helicase PF00580.21 CDJ57512.1 - 3.1 7.2 20.4 1.7 8.1 9.3 3.3 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain CEL_III_C PF18054.1 CDJ57513.1 - 8.2 6.5 9.5 0.64 10.1 1.6 2.6 2 0 0 2 2 2 0 CEL-III C-terminal PAP_assoc PF03828.19 CDJ57514.1 - 0.00098 19.3 0.6 0.012 15.8 0.2 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF4805 PF16063.5 CDJ57514.1 - 0.023 14.1 0.2 0.023 14.1 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4805) RPA43_OB PF17875.1 CDJ57514.1 - 0.028 15.1 1.3 1.3 9.6 0.1 3.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DDHD PF02862.17 CDJ57514.1 - 0.14 12.3 6.8 0.18 11.9 0.1 3.3 4 0 0 4 4 4 0 DDHD domain Ycf1 PF05758.12 CDJ57514.1 - 0.22 9.3 0.7 0.34 8.7 0.7 1.1 1 0 0 1 1 1 0 Ycf1 CLN3 PF02487.17 CDJ57514.1 - 0.46 9.5 1.3 1.2 8.1 1.3 1.6 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 CDJ57514.1 - 0.73 7.7 2.6 1.3 6.8 2.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CDJ57514.1 - 0.88 9.3 2.1 2.9 7.6 2.1 1.8 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 CDJ57514.1 - 1 8.0 1.9 1.8 7.2 1.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier Ureide_permease PF07168.11 CDJ57514.1 - 1.7 7.3 5.0 3.3 6.4 0.2 2.3 2 0 0 2 2 2 0 Ureide permease Ctr PF04145.15 CDJ57514.1 - 2.6 8.6 5.2 2.4 8.8 0.6 3.1 2 1 1 3 3 3 0 Ctr copper transporter family PIP5K PF01504.18 CDJ57515.1 - 0.0013 18.1 6.9 2.3 7.4 0.0 3.1 3 0 0 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase SUIM_assoc PF16619.5 CDJ57515.1 - 0.02 14.9 1.4 0.02 14.9 1.4 5.8 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PRIMA1 PF16101.5 CDJ57515.1 - 6.4 6.8 10.2 23 5.0 10.2 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 OTU PF02338.19 CDJ57516.1 - 2.8e-22 79.6 0.0 8.2e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease FAM199X PF15814.5 CDJ57516.1 - 0.0033 16.6 3.9 0.0033 16.6 3.9 2.0 2 0 0 2 2 2 1 Protein family FAM199X Peptidase_C65 PF10275.9 CDJ57516.1 - 0.075 12.5 2.1 1.6 8.1 0.0 2.6 2 1 0 3 3 3 0 Peptidase C65 Otubain BNR_assoc_N PF14873.6 CDJ57516.1 - 0.096 12.4 2.2 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase Cytomega_UL20A PF05984.12 CDJ57516.1 - 1.4 9.3 4.8 0.29 11.4 1.2 1.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein GAGA_bind PF06217.12 CDJ57516.1 - 1.5 9.0 6.6 2.7 8.2 6.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2722 PF10846.8 CDJ57520.1 - 0.001 18.1 3.1 0.001 18.1 3.1 11.0 9 3 1 10 10 10 5 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ57521.1 - 0.0023 17.6 11.4 0.0023 17.6 11.4 5.4 4 1 1 5 5 5 2 Spt20 family DUF4834 PF16118.5 CDJ57521.1 - 0.067 14.2 0.6 0.067 14.2 0.6 5.8 5 1 0 5 5 5 0 Domain of unknown function (DUF4834) Cytochrom_C PF00034.21 CDJ57522.1 - 1.6e-06 29.2 0.1 9.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDJ57522.1 - 0.0093 16.3 0.3 0.022 15.1 0.1 1.9 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDJ57522.1 - 0.01 15.5 0.1 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c-550 domain Spt20 PF12090.8 CDJ57522.1 - 0.079 12.6 3.3 0.1 12.2 3.3 1.1 1 0 0 1 1 1 0 Spt20 family GRP PF07172.11 CDJ57522.1 - 0.29 11.8 6.0 0.54 11.0 6.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF4718 PF15842.5 CDJ57523.1 - 0.0004 20.2 13.9 0.0004 20.2 13.9 5.0 4 1 2 6 6 6 1 Domain of unknown function (DUF4718) DUF1635 PF07795.11 CDJ57524.1 - 0.0091 15.9 15.9 0.43 10.4 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1635) RskA PF10099.9 CDJ57524.1 - 1.6 9.0 75.6 0.13 12.6 15.3 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA PI3K_1B_p101 PF10486.9 CDJ57524.1 - 2.6 5.7 14.7 3.5 5.3 14.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF755 PF05501.11 CDJ57524.1 - 4.9 7.4 28.0 1.8 8.9 19.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ57524.1 - 5.3 7.2 29.8 0.98 9.5 5.4 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PCI PF01399.27 CDJ57527.1 - 8.5e-06 26.2 0.2 1.2e-05 25.8 0.2 1.1 1 0 0 1 1 1 1 PCI domain Haem_oxygenas_2 PF14518.6 CDJ57527.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron-containing redox enzyme RNA_pol_Rpb2_7 PF04560.20 CDJ57528.1 - 2.6e-34 117.5 0.7 3.5e-34 117.1 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_6 PF00562.28 CDJ57528.1 - 3.4e-26 92.2 0.1 4.3e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 MRNIP PF15749.5 CDJ57528.1 - 0.5 11.1 2.8 0.76 10.5 2.8 1.3 1 0 0 1 1 1 0 MRN-interacting protein zf-C2H2_6 PF13912.6 CDJ57528.1 - 1.4 9.0 5.6 22 5.2 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TBP PF00352.21 CDJ57529.1 - 0.0017 18.3 0.0 0.0045 16.9 0.0 1.7 2 0 0 2 2 2 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF1126 PF06565.12 CDJ57530.1 - 2.3e-34 117.3 5.3 3.3e-17 62.2 0.0 3.5 3 1 1 4 4 4 3 DUF1126 PH-like domain DUF1043 PF06295.12 CDJ57532.1 - 0.0062 16.5 0.2 0.054 13.5 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1043) FAP206 PF12018.8 CDJ57532.1 - 0.076 12.5 0.2 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF2205 PF10224.9 CDJ57532.1 - 0.091 12.8 0.3 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Short coiled-coil protein Chorion_2 PF03964.15 CDJ57533.1 - 0.00014 22.6 0.8 0.00025 21.8 0.8 1.3 1 0 0 1 1 1 1 Chorion family 2 SR-25 PF10500.9 CDJ57533.1 - 0.059 13.0 9.7 0.092 12.3 9.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2852 PF11014.8 CDJ57533.1 - 0.063 13.4 1.3 0.21 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PI3K_1B_p101 PF10486.9 CDJ57533.1 - 3.3 5.4 5.9 4.4 4.9 5.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 CDJ57534.1 - 0.0025 17.2 24.9 0.0031 16.9 24.9 1.1 1 0 0 1 1 1 1 BUD22 O-antigen_lig PF13425.6 CDJ57534.1 - 0.041 12.7 6.4 0.051 12.4 6.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SPX PF03105.19 CDJ57534.1 - 0.05 13.5 23.8 0.086 12.7 23.8 1.4 1 0 0 1 1 1 0 SPX domain PIN_9 PF18477.1 CDJ57534.1 - 0.12 12.7 1.1 7.1 7.0 0.0 3.1 2 1 0 2 2 2 0 PIN like domain SR-25 PF10500.9 CDJ57534.1 - 0.13 11.9 37.7 0.58 9.7 18.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ57534.1 - 0.15 11.9 29.7 0.025 14.4 24.2 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 UPF0688 PF15772.5 CDJ57534.1 - 0.3 11.3 24.8 0.041 14.1 15.3 2.0 2 0 0 2 2 2 0 UPF0688 family DUF913 PF06025.12 CDJ57534.1 - 0.33 9.9 17.9 0.096 11.6 11.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Rer1 PF03248.13 CDJ57534.1 - 0.33 10.7 4.4 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 Rer1 family CDC45 PF02724.14 CDJ57534.1 - 0.36 9.1 28.1 0.011 14.1 19.3 1.9 2 0 0 2 2 2 0 CDC45-like protein Helicase_C PF00271.31 CDJ57534.1 - 0.43 11.0 11.3 0.85 10.0 1.1 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SLC12 PF03522.15 CDJ57534.1 - 0.62 9.0 28.6 0.088 11.8 22.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 DUF5427 PF10310.9 CDJ57534.1 - 1.3 7.9 33.2 0.23 10.4 25.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) SSP160 PF06933.11 CDJ57534.1 - 2.9 6.0 12.5 4.2 5.5 12.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCSAP PF15748.5 CDJ57534.1 - 3.4 7.8 39.4 0.9 9.7 29.2 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated U1snRNP70_N PF12220.8 CDJ57534.1 - 6.8 7.4 32.3 0.74 10.5 13.7 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2052 PF09747.9 CDJ57534.1 - 8.7 6.4 31.8 2.1 8.4 27.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2722 PF10846.8 CDJ57535.1 - 0.01 14.8 2.6 0.01 14.8 2.6 4.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ57535.1 - 0.012 15.3 5.8 0.012 15.3 5.8 3.9 3 1 0 3 3 3 0 Spt20 family SNF2_N PF00176.23 CDJ57535.1 - 0.023 13.4 0.1 0.023 13.4 0.1 2.5 4 0 0 4 4 4 0 SNF2 family N-terminal domain DUF3402 PF11882.8 CDJ57535.1 - 2.3 7.2 18.8 0.24 10.5 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3402) LMBR1 PF04791.16 CDJ57535.1 - 6.7 5.5 12.9 2.3 7.0 4.6 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein RskA PF10099.9 CDJ57537.1 - 0.21 11.9 20.6 0.31 11.3 20.6 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ndc1_Nup PF09531.10 CDJ57537.1 - 2.6 6.6 5.7 2.9 6.5 5.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 CDJ57537.1 - 2.6 7.0 6.5 3.6 6.5 6.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Smg8_Smg9 PF10220.9 CDJ57537.1 - 5.3 5.2 8.9 6.2 5.0 8.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 MRI PF15325.6 CDJ57537.1 - 5.7 8.1 21.4 0.55 11.3 13.9 2.2 1 1 1 2 2 2 0 Modulator of retrovirus infection Spt5-NGN PF03439.13 CDJ57538.1 - 0.00029 20.7 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 CDJ57538.1 - 0.0055 17.7 19.0 0.0055 17.7 19.0 3.1 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal SOBP PF15279.6 CDJ57538.1 - 1.1 9.8 7.6 1.5 9.4 7.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Med3 PF11593.8 CDJ57538.1 - 4.9 6.2 18.5 3.3 6.8 7.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 CDJ57538.1 - 6.1 5.4 8.7 6.6 5.3 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 CDJ57538.1 - 6.5 6.3 30.6 0.17 11.5 21.7 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4551 PF15087.6 CDJ57538.1 - 7.4 5.3 11.7 8.1 5.1 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SCO1-SenC PF02630.14 CDJ57540.1 - 4.4e-29 101.1 0.1 1e-28 99.9 0.1 1.6 1 0 0 1 1 1 1 SCO1/SenC TFIIA PF03153.13 CDJ57540.1 - 1.1e-05 25.7 36.2 1.8e-05 24.9 36.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ57540.1 - 0.016 15.3 42.8 0.032 14.3 42.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Hid1 PF12722.7 CDJ57540.1 - 0.028 12.6 14.2 0.036 12.2 14.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 CDJ57540.1 - 0.052 12.8 22.2 0.066 12.4 22.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AF-4 PF05110.13 CDJ57540.1 - 0.088 10.9 26.4 0.11 10.5 26.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Band_3_cyto PF07565.13 CDJ57540.1 - 0.13 12.0 16.8 0.22 11.3 16.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM176 PF14851.6 CDJ57540.1 - 0.5 10.0 6.8 1.1 8.9 6.8 1.7 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 CDJ57540.1 - 0.54 9.0 9.7 0.89 8.3 9.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 CDJ57540.1 - 0.78 7.9 31.0 1.1 7.5 31.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CDJ57540.1 - 1.9 7.9 14.6 2.9 7.3 14.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 CDJ57540.1 - 2.3 7.1 10.5 3.6 6.5 10.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 CDJ57540.1 - 2.6 7.4 8.5 2.2 7.6 7.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Zip PF02535.22 CDJ57540.1 - 4.3 6.5 6.4 6.7 5.8 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 CDJ57540.1 - 4.7 6.1 20.2 7.2 5.5 20.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CSG2 PF16965.5 CDJ57540.1 - 4.8 6.0 6.3 6.7 5.6 6.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 CDJ57540.1 - 5.9 6.6 9.6 12 5.6 9.6 1.6 1 0 0 1 1 1 0 Connexin Baculo_PP31 PF05311.11 CDJ57540.1 - 6.5 6.1 10.3 12 5.3 10.3 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) V_ATPase_I PF01496.19 CDJ57540.1 - 6.6 4.5 14.5 11 3.8 14.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CDJ57540.1 - 6.9 5.5 7.6 12 4.7 7.6 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ57540.1 - 7.1 5.5 18.2 11 4.9 18.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ57540.1 - 7.3 5.3 15.4 10 4.8 15.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CDJ57542.1 - 0.0038 17.3 23.0 0.0038 17.3 23.0 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit FXMRP1_C_core PF12235.8 CDJ57542.1 - 0.01 16.5 7.6 0.01 16.5 7.6 4.4 4 1 0 4 4 4 0 Fragile X-related 1 protein core C terminal CENP-B_dimeris PF09026.10 CDJ57542.1 - 0.027 14.8 4.6 0.027 14.8 4.6 2.8 2 1 0 2 2 1 0 Centromere protein B dimerisation domain DUF4407 PF14362.6 CDJ57542.1 - 0.054 12.8 15.5 0.087 12.2 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.13 CDJ57542.1 - 0.94 9.5 5.6 1.8 8.6 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Connexin PF00029.19 CDJ57542.1 - 1 9.0 9.2 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Connexin Activator_LAG-3 PF11498.8 CDJ57542.1 - 1.4 7.8 36.4 11 4.9 35.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RPN2_C PF18004.1 CDJ57542.1 - 3.6 7.5 12.8 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 CDJ57542.1 - 4.8 5.4 16.6 0.24 9.6 4.7 2.4 2 0 0 2 2 2 0 CDC45-like protein CLN3 PF02487.17 CDJ57542.1 - 6.9 5.6 7.0 1.3e+02 1.4 8.6 2.0 2 0 0 2 2 2 0 CLN3 protein HemX PF04375.14 CDJ57542.1 - 8.4 5.6 26.3 14 4.8 26.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SAP PF02037.27 CDJ57543.1 - 2.6e-14 52.6 0.0 6.9e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 CDJ57543.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP130_C PF16014.5 CDJ57543.1 - 1.3 8.0 9.1 1.7 7.7 9.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus FANC_SAP PF18081.1 CDJ57543.1 - 2.7 8.2 7.0 0.4 10.9 2.3 2.2 2 2 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Exonuc_VII_L PF02601.15 CDJ57544.1 - 0.51 9.9 13.8 0.61 9.6 13.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAT1 PF06391.13 CDJ57544.1 - 1.4 8.7 17.4 2.3 8.0 17.4 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DSPc PF00782.20 CDJ57545.1 - 1.2e-08 34.9 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDJ57545.1 - 5.1e-05 22.9 0.0 5.1e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDJ57545.1 - 0.0027 17.9 0.0 0.0029 17.7 0.0 1.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDJ57545.1 - 0.016 15.2 0.2 0.016 15.2 0.2 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family TatD_DNase PF01026.21 CDJ57545.1 - 0.095 12.1 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase DUF442 PF04273.13 CDJ57545.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Zip PF02535.22 CDJ57546.1 - 5.5e-20 71.8 8.1 7.9e-20 71.3 8.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter ISG65-75 PF11727.8 CDJ57546.1 - 0.18 11.0 5.6 0.36 10.0 5.6 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein RNA_pol_L PF01193.24 CDJ57548.1 - 1.4e-10 40.4 0.0 1.4e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CDJ57548.1 - 4.5e-06 27.0 0.1 8.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain MSP1_C PF07462.11 CDJ57548.1 - 0.025 13.3 3.2 0.029 13.1 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RskA PF10099.9 CDJ57548.1 - 0.25 11.6 21.9 0.35 11.2 21.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ57548.1 - 3.1 7.7 10.2 3.5 7.5 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ57548.1 - 7.8 5.1 15.5 9.1 4.8 15.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NAP PF00956.18 CDJ57549.1 - 2.7e-51 174.3 8.4 1.8e-31 109.3 1.0 3.1 3 1 0 3 3 3 2 Nucleosome assembly protein (NAP) Ribosomal_60s PF00428.19 CDJ57549.1 - 0.029 15.0 6.9 0.029 15.0 6.9 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ57549.1 - 2 6.9 8.4 0.88 8.1 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Gpi16 PF04113.14 CDJ57551.1 - 9.7e-23 80.4 9.4 4.8e-21 74.8 9.7 2.8 1 1 1 2 2 2 1 Gpi16 subunit, GPI transamidase component Perilipin PF03036.16 CDJ57551.1 - 0.0019 17.3 9.7 0.0019 17.3 9.7 3.2 3 0 0 3 3 3 1 Perilipin family Otopetrin PF03189.13 CDJ57551.1 - 0.15 10.9 3.0 0.53 9.0 0.1 2.2 2 0 0 2 2 2 0 Otopetrin Peptidase_C2 PF00648.21 CDJ57552.1 - 3.2e-17 62.5 8.1 4.7e-13 48.8 0.0 3.0 2 1 1 3 3 3 2 Calpain family cysteine protease TFIIA PF03153.13 CDJ57552.1 - 3.6e-08 33.8 24.7 3.6e-08 33.8 24.7 4.0 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ57552.1 - 0.00069 19.7 16.2 0.00069 19.7 16.2 3.4 2 1 0 2 2 2 1 SPX domain Lin-8 PF03353.15 CDJ57552.1 - 0.0039 16.8 20.2 0.0039 16.8 20.2 3.9 4 0 0 4 4 4 1 Ras-mediated vulval-induction antagonist DUF2126 PF09899.9 CDJ57552.1 - 2.7 5.9 12.9 5.8 4.9 12.9 1.5 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Otopetrin PF03189.13 CDJ57552.1 - 5 5.8 13.7 0.022 13.6 2.3 2.5 2 1 0 2 2 2 0 Otopetrin Velvet PF11754.8 CDJ57554.1 - 0.00036 20.6 11.0 0.00053 20.0 11.0 1.2 1 0 0 1 1 1 1 Velvet factor Rep_1 PF01446.17 CDJ57554.1 - 0.03 13.8 1.5 0.03 13.8 1.5 2.4 3 0 0 3 3 3 0 Replication protein Phage_Gp15 PF06854.11 CDJ57554.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.0 1 1 1 3 3 3 0 Bacteriophage Gp15 protein DUF4400 PF14348.6 CDJ57554.1 - 1.2 8.6 4.1 2 7.9 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PAT1 PF09770.9 CDJ57554.1 - 1.8 6.8 28.0 2.7 6.2 28.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.6 CDJ57554.1 - 2.4 8.6 6.3 0.58 10.6 0.2 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal V_ATPase_I PF01496.19 CDJ57554.1 - 7.5 4.3 12.1 0.35 8.7 6.6 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PNISR PF15996.5 CDJ57554.1 - 9.6 6.4 23.7 5.2 7.3 17.2 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RF-1 PF00472.20 CDJ57555.1 - 3.6e-30 104.3 9.1 3.6e-30 104.3 9.1 1.7 2 0 0 2 2 2 1 RF-1 domain Menin PF05053.13 CDJ57555.1 - 0.00082 17.9 4.3 0.001 17.6 4.3 1.1 1 0 0 1 1 1 1 Menin Sel1 PF08238.12 CDJ57556.1 - 4.6e-13 49.4 24.5 5.2e-06 27.0 1.2 7.6 9 0 0 9 9 9 3 Sel1 repeat SUIM_assoc PF16619.5 CDJ57556.1 - 5.8e-08 32.7 10.4 0.0036 17.3 0.0 4.9 2 2 2 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 TPR_16 PF13432.6 CDJ57556.1 - 0.23 12.1 0.0 0.23 12.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ57556.1 - 0.32 11.1 3.3 4.3 7.6 1.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2722 PF10846.8 CDJ57556.1 - 2.9 6.7 27.3 0.096 11.6 4.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) PrmA PF06325.13 CDJ57557.1 - 1.3e-10 41.2 0.3 1.3e-10 41.2 0.3 2.6 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDJ57557.1 - 5e-09 36.7 0.0 1.8e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ57557.1 - 1.7e-07 31.2 0.0 1.7e-07 31.2 0.0 3.4 2 2 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CDJ57557.1 - 4.2e-07 29.7 0.0 9.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CDJ57557.1 - 1.3e-06 28.9 0.4 9.2e-06 26.2 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ57557.1 - 5.8e-06 26.2 2.3 5.8e-06 26.2 2.3 2.5 2 1 0 2 2 2 1 Methyltransferase domain Spt20 PF12090.8 CDJ57557.1 - 0.00022 20.9 46.4 0.0031 17.1 14.7 2.9 3 0 0 3 3 3 2 Spt20 family Methyltransf_12 PF08242.12 CDJ57557.1 - 0.00044 20.9 0.0 0.00044 20.9 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ57557.1 - 0.00056 19.9 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDJ57557.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 2.4 3 0 0 3 3 2 1 Conserved hypothetical protein 95 RskA PF10099.9 CDJ57557.1 - 0.0034 17.7 30.5 0.51 10.6 6.1 5.2 3 2 0 3 3 2 2 Anti-sigma-K factor rskA Methyltransf_9 PF08003.11 CDJ57557.1 - 0.0055 15.7 0.0 0.0055 15.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1698) PCMT PF01135.19 CDJ57557.1 - 0.0083 15.9 0.1 0.0083 15.9 0.1 2.2 2 0 0 2 2 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ANAPC_CDC26 PF10471.9 CDJ57557.1 - 0.036 14.9 10.6 0.036 14.9 10.6 6.0 6 0 0 6 6 5 0 Anaphase-promoting complex APC subunit CDC26 Topoisom_I_N PF02919.15 CDJ57557.1 - 0.037 13.5 7.1 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Ubie_methyltran PF01209.18 CDJ57557.1 - 0.046 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CDJ57557.1 - 0.052 13.3 0.2 0.13 12.0 0.0 1.7 2 0 0 2 2 1 0 Lysine methyltransferase Met_10 PF02475.16 CDJ57557.1 - 0.055 13.2 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ydc2-catalyt PF09159.10 CDJ57557.1 - 0.094 12.4 7.2 6.9 6.3 2.9 3.2 3 0 0 3 3 3 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 TehB PF03848.14 CDJ57557.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB AAA_23 PF13476.6 CDJ57557.1 - 0.18 12.3 17.3 0.15 12.6 4.1 2.3 2 0 0 2 2 2 0 AAA domain Methyltransf_32 PF13679.6 CDJ57557.1 - 0.23 11.5 0.0 0.23 11.5 0.0 4.0 3 1 0 3 3 2 0 Methyltransferase domain PIP5K PF01504.18 CDJ57557.1 - 0.23 10.6 8.3 1.3 8.2 2.4 2.5 3 0 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase Pep_M12B_propep PF01562.19 CDJ57557.1 - 0.51 10.6 6.8 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 Reprolysin family propeptide PAT1 PF09770.9 CDJ57557.1 - 2 6.6 27.8 0.6 8.3 10.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MAGE PF01454.19 CDJ57557.1 - 2.3 7.9 14.6 0.44 10.2 3.0 2.4 2 0 0 2 2 2 0 MAGE family DUF1151 PF06625.11 CDJ57557.1 - 3.2 7.7 29.8 0.6 10.1 14.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) PPL5 PF18168.1 CDJ57557.1 - 3.7 6.8 9.2 2 7.6 2.3 2.6 2 0 0 2 2 2 0 Prim-pol family 5 GramPos_pilinD1 PF16555.5 CDJ57557.1 - 4 7.6 10.4 1.1 9.4 0.6 3.2 3 0 0 3 3 3 0 Gram-positive pilin subunit D1, N-terminal domain FYDLN_acid PF09538.10 CDJ57558.1 - 0.00031 21.4 15.2 0.00031 21.4 15.2 7.2 5 2 1 6 6 6 1 Protein of unknown function (FYDLN_acid) Spore_coat_CotO PF14153.6 CDJ57559.1 - 0.0011 18.9 12.0 0.0011 18.9 12.0 8.5 4 3 3 8 8 8 1 Spore coat protein CotO Citrate_synt PF00285.21 CDJ57561.1 - 0.0063 15.6 0.0 0.15 11.1 0.0 2.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain SR-25 PF10500.9 CDJ57562.1 - 0.00051 19.7 8.0 0.00051 19.7 8.0 3.5 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ57562.1 - 0.0023 17.9 29.4 0.11 12.4 0.9 2.1 2 0 0 2 2 2 2 SPX domain Ribosomal_60s PF00428.19 CDJ57562.1 - 0.0052 17.3 10.9 0.0052 17.3 10.9 3.9 3 1 0 3 3 3 1 60s Acidic ribosomal protein Ndc1_Nup PF09531.10 CDJ57562.1 - 0.062 12.0 25.5 0.24 10.1 13.6 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GET2 PF08690.10 CDJ57562.1 - 0.31 10.7 36.3 0.46 10.1 23.1 2.6 3 0 0 3 3 3 0 GET complex subunit GET2 LAP1C PF05609.12 CDJ57562.1 - 1.8 7.5 35.1 0.69 8.9 22.3 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SART-1 PF03343.13 CDJ57562.1 - 7.8 4.9 28.6 1.3 7.5 16.8 2.2 2 0 0 2 2 2 0 SART-1 family His_Phos_1 PF00300.22 CDJ57563.1 - 5.8e-12 45.7 11.4 2e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TFIIA PF03153.13 CDJ57563.1 - 0.0073 16.3 4.2 0.0076 16.3 4.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 CDJ57563.1 - 0.056 12.5 4.0 0.065 12.3 4.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_M8 PF01457.16 CDJ57563.1 - 0.057 12.1 1.5 0.074 11.7 1.5 1.0 1 0 0 1 1 1 0 Leishmanolysin Herpes_UL74 PF07982.12 CDJ57563.1 - 0.094 11.7 1.5 0.12 11.3 1.5 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Sporozoite_P67 PF05642.11 CDJ57563.1 - 0.25 9.4 3.0 0.3 9.1 3.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 CDJ57563.1 - 0.43 10.1 12.8 0.57 9.8 12.8 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ57563.1 - 0.64 10.1 14.3 1.2 9.2 14.3 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 CDJ57563.1 - 0.73 8.4 9.5 0.85 8.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BAT2_N PF07001.11 CDJ57563.1 - 0.98 9.9 10.0 1.3 9.5 10.0 1.1 1 0 0 1 1 1 0 BAT2 N-terminus IPK PF03770.16 CDJ57564.1 - 3.9e-34 118.2 0.0 3.9e-34 118.2 0.0 4.4 4 2 0 4 4 4 1 Inositol polyphosphate kinase Kinesin PF00225.23 CDJ57565.1 - 5.1e-08 32.2 0.1 5.1e-08 32.2 0.1 6.9 5 2 1 6 6 6 3 Kinesin motor domain RskA PF10099.9 CDJ57567.1 - 0.0031 17.8 1.6 0.0031 17.8 1.6 5.8 2 2 2 5 5 5 2 Anti-sigma-K factor rskA DUF898 PF05987.13 CDJ57567.1 - 0.68 8.9 4.9 0.27 10.2 0.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4834 PF16118.5 CDJ57567.1 - 4.8 8.2 42.2 2.4 9.2 0.6 6.4 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) Shadoo PF14999.6 CDJ57567.1 - 7.4 6.7 15.7 0.77 9.9 2.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective ABC_tran PF00005.27 CDJ57568.1 - 4.7e-20 72.5 0.0 4.7e-20 72.5 0.0 4.9 3 2 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 CDJ57568.1 - 1.6e-08 34.7 0.0 8.6e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ57568.1 - 0.00058 19.4 0.0 0.002 17.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDJ57568.1 - 0.0078 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ57568.1 - 0.029 14.3 0.1 0.029 14.3 0.1 3.1 3 0 0 3 3 3 0 RsgA GTPase AAA_23 PF13476.6 CDJ57568.1 - 0.23 11.9 0.0 0.23 11.9 0.0 4.6 3 1 1 4 4 4 0 AAA domain AAA_28 PF13521.6 CDJ57568.1 - 0.8 9.9 0.0 0.8 9.9 0.0 4.9 5 0 0 5 5 5 0 AAA domain Cyt_bd_oxida_II PF02322.15 CDJ57569.1 - 0.14 11.5 3.5 0.23 10.8 3.5 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Med3 PF11593.8 CDJ57569.1 - 0.24 10.5 18.3 4.1 6.5 17.2 2.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ57570.1 - 0.17 12.2 13.8 0.35 11.1 13.8 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ57570.1 - 0.17 11.8 10.3 0.26 11.3 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 CDJ57570.1 - 3.9 6.5 14.9 5.1 6.1 14.9 1.4 1 1 0 1 1 1 0 Protein family of FAM222A DUF2722 PF10846.8 CDJ57572.1 - 4.2e-06 26.0 10.9 4.2e-06 26.0 10.9 4.0 4 0 0 4 4 3 1 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ57572.1 - 0.0054 15.6 2.6 0.0054 15.6 2.6 2.7 3 0 0 3 3 3 1 Presenilin SpoIIP PF07454.11 CDJ57572.1 - 0.012 15.0 2.1 0.012 15.0 2.1 2.5 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) SR-25 PF10500.9 CDJ57572.1 - 0.016 14.8 20.9 0.48 10.0 11.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4484 PF14831.6 CDJ57572.1 - 0.035 14.1 0.3 0.035 14.1 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) MRI PF15325.6 CDJ57572.1 - 0.44 11.7 9.7 4.8 8.3 0.3 3.2 2 0 0 2 2 2 0 Modulator of retrovirus infection Plasmodium_Vir PF05795.11 CDJ57572.1 - 1.3 8.4 3.6 1.5 8.1 0.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MTP18 PF10558.9 CDJ57572.1 - 1.3 8.9 5.0 14 5.6 1.1 2.9 3 0 0 3 3 3 0 Mitochondrial 18 KDa protein (MTP18) Gti1_Pac2 PF09729.9 CDJ57572.1 - 1.4 9.0 10.8 0.26 11.4 0.5 2.7 3 0 0 3 3 3 0 Gti1/Pac2 family DUF1645 PF07816.11 CDJ57572.1 - 1.4 9.5 13.4 2.9 8.4 3.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) AIF_C PF14721.6 CDJ57572.1 - 1.7 9.0 11.6 0.1 12.9 1.9 3.2 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AAA_23 PF13476.6 CDJ57572.1 - 2.2 8.7 19.1 0.12 12.8 4.2 3.1 3 0 0 3 3 3 0 AAA domain CCDC106 PF15794.5 CDJ57572.1 - 3.5 7.3 18.4 2.2 8.0 4.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 MecA PF05389.12 CDJ57572.1 - 5.3 6.6 10.9 0.055 13.1 0.6 2.6 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 CDJ57572.1 - 7.6 6.5 12.5 0.58 10.1 2.0 2.8 3 0 0 3 3 3 0 Protein Family FAM60A Peptidase_U57 PF05582.12 CDJ57572.1 - 9.3 5.4 10.0 0.31 10.3 2.4 2.2 2 0 0 2 2 2 0 YabG peptidase U57 DnaJ PF00226.31 CDJ57573.1 - 1e-06 28.7 0.0 1e-06 28.7 0.0 3.3 3 0 0 3 3 3 1 DnaJ domain DUF572 PF04502.13 CDJ57573.1 - 0.6 9.7 42.3 0.054 13.1 18.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ57575.1 - 0.00019 21.1 24.9 0.00019 21.1 24.9 4.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Mem_trans PF03547.18 CDJ57575.1 - 0.0012 17.3 4.6 0.0012 17.3 4.6 3.2 3 0 0 3 3 3 1 Membrane transport protein Peptidase_S64 PF08192.11 CDJ57575.1 - 0.0016 17.0 17.4 0.0016 17.0 17.4 3.0 2 1 1 3 3 3 1 Peptidase family S64 Plasmodium_Vir PF05795.11 CDJ57575.1 - 0.003 17.1 4.5 0.003 17.1 4.5 3.7 3 1 0 4 4 4 1 Plasmodium vivax Vir protein PAP1 PF08601.10 CDJ57575.1 - 0.0048 16.7 12.2 0.0048 16.7 12.2 3.8 3 1 1 4 4 4 1 Transcription factor PAP1 MFS_1_like PF12832.7 CDJ57575.1 - 0.055 12.3 0.0 0.72 8.6 0.0 2.3 1 1 0 1 1 1 0 MFS_1 like family Ribosomal_60s PF00428.19 CDJ57576.1 - 5.8e-05 23.6 5.7 5.8e-05 23.6 5.7 2.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1645 PF07816.11 CDJ57576.1 - 0.017 15.7 5.0 0.017 15.7 5.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) Sin_N PF04801.13 CDJ57576.1 - 0.1 11.8 35.3 0.17 11.1 35.3 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region BUD22 PF09073.10 CDJ57576.1 - 0.21 10.9 21.2 0.075 12.4 18.2 1.7 2 1 0 2 2 2 0 BUD22 Borrelia_P83 PF05262.11 CDJ57576.1 - 0.44 9.0 20.4 0.61 8.5 20.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SARAF PF06682.12 CDJ57576.1 - 1.8 8.1 24.2 4.6 6.8 24.2 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Trp_oprn_chp PF09534.10 CDJ57576.1 - 2.9 7.7 20.6 3.4 7.4 1.7 3.3 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5523 PF17661.1 CDJ57576.1 - 6.3 6.4 23.3 6.4 6.4 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF2000 PF09391.10 CDJ57576.1 - 7.4 6.5 12.1 0.18 11.7 2.6 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2000) DAG_kinase_N PF14513.6 CDJ57576.1 - 8.9 6.5 25.5 5 7.3 11.9 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus tRNA-synt_1c_C PF03950.18 CDJ57577.1 - 1.5e-21 77.1 0.0 3.6e-11 43.2 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), anti-codon binding domain DUF2722 PF10846.8 CDJ57578.1 - 0.0048 15.9 0.4 0.0048 15.9 0.4 12.1 7 2 4 12 12 12 1 Protein of unknown function (DUF2722) CDC27 PF09507.10 CDJ57579.1 - 0.34 10.2 2.5 0.52 9.6 2.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Actin PF00022.19 CDJ57580.1 - 1.1e-22 80.2 1.1 2.2e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Actin SUIM_assoc PF16619.5 CDJ57580.1 - 0.012 15.7 0.5 0.012 15.7 0.5 5.4 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 mTERF PF02536.14 CDJ57580.1 - 0.035 13.0 2.3 0.053 12.4 2.3 1.2 1 0 0 1 1 1 0 mTERF DUF573 PF04504.14 CDJ57580.1 - 0.86 10.3 6.1 0.11 13.2 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 GREB1 PF15782.5 CDJ57580.1 - 2.1 5.4 9.8 2.8 4.9 9.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PH_4 PF15404.6 CDJ57580.1 - 9.2 6.0 10.7 24 4.7 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain SMC_N PF02463.19 CDJ57581.1 - 5e-13 49.0 1.4 3.1e-12 46.4 1.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ57581.1 - 7.2e-08 32.8 0.3 3.5e-07 30.5 0.3 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ57581.1 - 7.9e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDJ57581.1 - 0.00095 19.4 0.4 0.00095 19.4 0.4 3.8 4 0 0 4 4 4 1 Putative exonuclease SbcCD, C subunit DUF4952 PF16310.5 CDJ57581.1 - 0.27 11.5 2.4 2.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Domian of unknown function (DUF4952) Adeno_PV PF03910.13 CDJ57582.1 - 0.46 9.1 5.6 1 8.0 5.6 1.6 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2052 PF09747.9 CDJ57583.1 - 8.1e-05 22.8 40.8 0.02 15.0 11.9 3.3 3 0 0 3 3 3 3 Coiled-coil domain containing protein (DUF2052) Spt20 PF12090.8 CDJ57583.1 - 0.00044 20.0 61.1 0.016 14.8 18.1 3.8 4 0 0 4 4 4 3 Spt20 family FmiP_Thoc5 PF09766.9 CDJ57583.1 - 0.00045 19.6 3.3 0.00045 19.6 3.3 3.1 3 0 0 3 3 3 1 Fms-interacting protein/Thoc5 MIF4G_like_2 PF09090.11 CDJ57583.1 - 0.0031 17.0 0.0 0.0031 17.0 0.0 4.3 4 0 0 4 4 3 1 MIF4G like DUF3807 PF12720.7 CDJ57583.1 - 0.0046 17.3 40.4 0.24 11.7 9.9 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3807) HABP4_PAI-RBP1 PF04774.15 CDJ57583.1 - 0.0084 16.9 4.4 0.0084 16.9 4.4 4.6 3 2 0 3 3 1 1 Hyaluronan / mRNA binding family DUF913 PF06025.12 CDJ57583.1 - 0.056 12.4 23.4 0.18 10.8 1.1 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) OsmC PF02566.19 CDJ57583.1 - 0.17 12.3 2.7 0.58 10.7 2.7 1.9 1 0 0 1 1 1 0 OsmC-like protein EPL1 PF10513.9 CDJ57583.1 - 0.24 11.8 29.2 0.026 14.9 4.0 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF4746 PF15928.5 CDJ57583.1 - 0.26 10.7 34.1 0.037 13.5 4.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 CDJ57583.1 - 0.28 10.7 33.0 0.34 10.4 7.1 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF1943 PF09172.11 CDJ57583.1 - 2.6 7.2 9.9 3.7 6.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Nha1_C PF08619.10 CDJ57583.1 - 3.8 6.6 39.6 0.091 12.0 2.9 3.2 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM60A PF15396.6 CDJ57583.1 - 4.5 7.2 19.4 1.6 8.7 1.4 3.2 3 0 0 3 3 3 0 Protein Family FAM60A Connexin PF00029.19 CDJ57583.1 - 6.4 6.5 25.9 10 5.8 4.6 3.2 3 0 0 3 3 3 0 Connexin eIF-3_zeta PF05091.12 CDJ57583.1 - 8.8 5.2 32.2 0.086 11.8 6.6 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.12 CDJ57583.1 - 9.9 5.7 24.8 0.7 9.5 4.4 3.6 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) DUF1645 PF07816.11 CDJ57584.1 - 0.0002 22.0 18.0 0.00044 20.9 10.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) RskA PF10099.9 CDJ57584.1 - 0.00037 20.8 14.5 0.00037 20.8 14.5 2.9 1 1 1 2 2 1 1 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ57584.1 - 0.0031 17.2 29.3 0.085 12.5 10.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4207) Activator_LAG-3 PF11498.8 CDJ57584.1 - 0.06 12.3 68.8 0.088 11.8 68.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF5523 PF17661.1 CDJ57584.1 - 0.33 10.6 19.2 0.71 9.5 7.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Mak16 PF04874.14 CDJ57584.1 - 0.43 11.2 14.2 1.3 9.7 6.4 2.4 2 0 0 2 2 2 0 Mak16 protein C-terminal region DnaJ-X PF14308.6 CDJ57584.1 - 0.49 9.8 10.7 2.5 7.5 5.0 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing RPA43_OB PF17875.1 CDJ57584.1 - 0.57 10.8 14.7 0.35 11.5 2.6 2.6 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Pinin_SDK_memA PF04696.13 CDJ57584.1 - 0.62 10.1 33.2 1.1 9.3 9.5 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Eapp_C PF10238.9 CDJ57584.1 - 0.64 10.1 19.9 1.9 8.6 6.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4666 PF15697.5 CDJ57584.1 - 0.66 10.7 15.2 0.13 13.0 0.7 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4666) MCU PF04678.13 CDJ57584.1 - 0.7 10.0 11.4 1.7 8.7 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Connexin PF00029.19 CDJ57584.1 - 0.82 9.4 14.7 1.4 8.7 3.9 2.2 2 0 0 2 2 2 0 Connexin EIIBC-GUT_N PF03612.14 CDJ57584.1 - 0.94 9.2 17.0 1.7 8.3 4.5 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PRP1_N PF06424.12 CDJ57584.1 - 1 9.8 15.9 3.9 7.9 5.7 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SLC12 PF03522.15 CDJ57584.1 - 1.1 8.2 19.4 1.7 7.6 19.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 CDJ57584.1 - 1.2 8.8 13.4 0.64 9.7 4.0 2.4 2 0 0 2 2 2 0 FAM176 family HGTP_anticodon2 PF12745.7 CDJ57584.1 - 1.4 8.4 18.7 0.082 12.4 4.1 2.4 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs SR-25 PF10500.9 CDJ57584.1 - 1.4 8.5 28.0 3.2 7.3 0.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein NPR1_interact PF15699.5 CDJ57584.1 - 2.5 8.8 19.0 6.4 7.4 3.0 2.4 2 0 0 2 2 2 0 NPR1 interacting DUF4199 PF13858.6 CDJ57584.1 - 3.1 8.2 17.0 4.5 7.6 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Folate_carrier PF01770.18 CDJ57584.1 - 4.1 6.0 14.4 3.4 6.3 3.2 2.2 2 0 0 2 2 2 0 Reduced folate carrier G0-G1_switch_2 PF15103.6 CDJ57584.1 - 4.3 7.8 14.3 5.1 7.6 3.1 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Pex26 PF07163.12 CDJ57584.1 - 4.9 6.4 21.2 0.85 8.9 4.8 2.4 2 0 0 2 2 2 0 Pex26 protein Thg1C PF14413.6 CDJ57584.1 - 5.1 7.3 16.4 5.6 7.2 2.3 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain DUF3464 PF11947.8 CDJ57584.1 - 5.4 6.7 20.1 1.1 9.0 5.1 2.5 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 FYDLN_acid PF09538.10 CDJ57584.1 - 7.8 7.2 18.5 2.8 8.6 4.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 CDJ57585.1 - 8.8e-06 24.7 15.4 1.2e-05 24.3 15.4 1.1 1 0 0 1 1 1 1 Presenilin Pex14_N PF04695.13 CDJ57585.1 - 7.2e-05 23.5 24.5 0.0065 17.1 9.3 2.1 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region GNAT_acetyltr_2 PF13718.6 CDJ57585.1 - 0.00016 21.2 12.0 0.00086 18.8 1.6 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase 2 SAPS PF04499.15 CDJ57585.1 - 0.0005 19.0 6.4 0.00063 18.6 6.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SpoIIP PF07454.11 CDJ57585.1 - 0.0014 18.1 17.8 0.021 14.3 5.2 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) AIF_C PF14721.6 CDJ57585.1 - 0.0015 18.9 12.1 0.031 14.6 1.6 2.1 2 0 0 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.14 CDJ57585.1 - 0.0015 18.5 19.8 0.077 13.0 7.6 2.1 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) DUF2370 PF10176.9 CDJ57585.1 - 0.0016 18.1 3.8 0.038 13.6 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) V_ATPase_I PF01496.19 CDJ57585.1 - 0.0024 15.9 14.9 0.069 11.1 2.6 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Rxt3 PF08642.10 CDJ57585.1 - 0.0026 18.5 7.7 0.29 11.9 0.4 2.2 2 0 0 2 2 2 2 Histone deacetylation protein Rxt3 FAM60A PF15396.6 CDJ57585.1 - 0.0039 17.2 10.5 0.053 13.5 1.2 2.1 2 0 0 2 2 2 2 Protein Family FAM60A CCDC53 PF10152.9 CDJ57585.1 - 0.0055 17.1 16.8 0.27 11.6 5.9 2.1 2 0 0 2 2 2 2 Subunit CCDC53 of WASH complex RNA_pol_Rpc4 PF05132.14 CDJ57585.1 - 0.0065 16.9 12.7 0.31 11.5 5.0 2.1 2 0 0 2 2 2 2 RNA polymerase III RPC4 CPSF100_C PF13299.6 CDJ57585.1 - 0.0078 16.4 19.7 0.16 12.2 9.0 2.1 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal DUF4050 PF13259.6 CDJ57585.1 - 0.0096 16.3 12.7 0.076 13.3 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) PIEZO PF15917.5 CDJ57585.1 - 0.012 15.1 23.0 0.15 11.5 8.6 2.1 2 0 0 2 2 2 0 Piezo Spt20 PF12090.8 CDJ57585.1 - 0.013 15.1 13.1 0.013 15.1 13.1 2.1 2 0 0 2 2 2 0 Spt20 family FAM176 PF14851.6 CDJ57585.1 - 0.018 14.7 15.9 0.16 11.7 4.8 2.1 2 0 0 2 2 2 0 FAM176 family EPL1 PF10513.9 CDJ57585.1 - 0.019 15.4 21.6 0.036 14.4 6.0 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4628 PF15429.6 CDJ57585.1 - 0.022 14.5 15.4 0.17 11.6 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) RR_TM4-6 PF06459.12 CDJ57585.1 - 0.024 14.5 20.4 0.39 10.5 4.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ57585.1 - 0.025 13.6 9.0 0.11 11.4 1.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ57585.1 - 0.028 14.2 14.6 0.12 12.1 3.8 2.1 2 0 0 2 2 2 0 Connexin Peroxin-13_N PF04088.13 CDJ57585.1 - 0.033 14.5 9.2 1.7 8.9 0.2 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2126 PF09899.9 CDJ57585.1 - 0.037 12.1 13.5 0.054 11.6 13.5 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAM76 PF16046.5 CDJ57585.1 - 0.039 13.3 15.6 0.11 11.8 4.8 2.1 2 0 0 2 2 2 0 FAM76 protein Lin-8 PF03353.15 CDJ57585.1 - 0.045 13.3 20.2 0.43 10.1 7.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2076 PF09849.9 CDJ57585.1 - 0.049 13.7 33.1 0.49 10.4 17.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2722 PF10846.8 CDJ57585.1 - 0.05 12.5 46.2 0.073 12.0 20.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PAP_RNA-bind PF04926.15 CDJ57585.1 - 0.062 12.9 13.6 0.051 13.2 2.5 2.1 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain CLN3 PF02487.17 CDJ57585.1 - 0.072 12.1 11.8 0.068 12.2 2.0 2.1 2 0 0 2 2 2 0 CLN3 protein RPA43_OB PF17875.1 CDJ57585.1 - 0.085 13.5 12.7 0.73 10.5 1.5 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I TRAP_alpha PF03896.16 CDJ57585.1 - 0.086 12.0 12.5 0.25 10.5 0.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF719 PF05334.13 CDJ57585.1 - 0.095 12.9 16.7 0.13 12.5 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) CRA PF06589.11 CDJ57585.1 - 0.097 12.8 2.7 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) GTA_holin_3TM PF11351.8 CDJ57585.1 - 0.099 13.2 18.8 0.13 12.8 5.1 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release CobT PF06213.12 CDJ57585.1 - 0.11 11.9 36.6 0.047 13.1 13.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ctr PF04145.15 CDJ57585.1 - 0.11 13.1 9.7 0.5 11.0 1.7 2.1 2 0 0 2 2 2 0 Ctr copper transporter family DUF4834 PF16118.5 CDJ57585.1 - 0.11 13.5 24.7 1.7 9.6 6.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Vfa1 PF08432.10 CDJ57585.1 - 0.11 12.8 20.6 0.66 10.3 4.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TERB2 PF15101.6 CDJ57585.1 - 0.13 12.3 27.8 0.042 13.9 3.1 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3347 PF11827.8 CDJ57585.1 - 0.14 12.3 13.1 0.75 10.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) NPR3 PF03666.13 CDJ57585.1 - 0.15 10.8 16.8 0.091 11.5 0.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PTPRCAP PF15713.5 CDJ57585.1 - 0.18 12.1 26.0 0.28 11.5 8.6 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF775 PF05603.12 CDJ57585.1 - 0.19 11.2 17.0 0.2 11.1 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) PBP1_TM PF14812.6 CDJ57585.1 - 0.21 12.0 13.3 0.37 11.2 1.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BORG_CEP PF14957.6 CDJ57585.1 - 0.23 12.6 10.7 2.9 9.1 3.3 2.1 2 0 0 2 2 2 0 Cdc42 effector TMEM51 PF15345.6 CDJ57585.1 - 0.23 11.3 26.6 1.2 8.9 9.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DNA_pol_delta_4 PF04081.13 CDJ57585.1 - 0.25 11.7 17.4 1.5 9.2 5.2 2.2 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 Radial_spoke PF04712.12 CDJ57585.1 - 0.25 10.2 21.0 0.057 12.4 5.3 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein BSMAP PF12280.8 CDJ57585.1 - 0.29 11.3 12.3 1.5 9.0 3.0 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein D123 PF07065.14 CDJ57585.1 - 0.3 10.2 12.9 0.64 9.1 0.8 2.1 2 0 0 2 2 2 0 D123 DUF2203 PF09969.9 CDJ57585.1 - 0.32 11.7 17.4 0.87 10.3 2.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ANXA2R PF15721.5 CDJ57585.1 - 0.41 11.1 13.7 2.5 8.6 0.7 2.2 2 0 0 2 2 2 0 Annexin-2 receptor EIIBC-GUT_N PF03612.14 CDJ57585.1 - 0.42 10.3 19.4 0.22 11.2 4.9 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FYDLN_acid PF09538.10 CDJ57585.1 - 0.46 11.2 16.9 2.4 8.9 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CSG2 PF16965.5 CDJ57585.1 - 0.47 9.3 9.4 0.24 10.3 1.9 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator MRNIP PF15749.5 CDJ57585.1 - 0.73 10.6 29.7 2.8 8.7 8.3 2.1 2 0 0 2 2 2 0 MRN-interacting protein DUF4045 PF13254.6 CDJ57585.1 - 0.81 9.3 15.7 1.8 8.1 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF4175 PF13779.6 CDJ57585.1 - 0.84 7.5 45.1 1.2 6.9 23.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2072 PF09845.9 CDJ57585.1 - 0.86 9.9 13.4 3.3 8.0 1.7 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein PRC2_HTH_1 PF18118.1 CDJ57585.1 - 0.92 10.3 20.2 4.6 8.1 8.8 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Band_3_cyto PF07565.13 CDJ57585.1 - 0.92 9.3 18.3 2 8.2 3.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RNA_pol_Rbc25 PF08292.12 CDJ57585.1 - 0.95 9.7 17.2 2.1 8.6 4.2 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 FmiP_Thoc5 PF09766.9 CDJ57585.1 - 0.97 8.7 27.2 1.4 8.1 12.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Hydin_ADK PF17213.3 CDJ57585.1 - 0.97 9.7 11.3 2.5 8.4 2.8 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain LRRC37AB_C PF14914.6 CDJ57585.1 - 0.98 9.3 16.6 0.12 12.3 3.8 2.1 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain AAR2 PF05282.11 CDJ57585.1 - 1.1 8.5 11.5 2.6 7.4 1.3 2.0 2 0 0 2 2 2 0 AAR2 protein RICTOR_N PF14664.6 CDJ57585.1 - 1.2 8.1 7.6 1.3 7.9 0.7 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DUF5523 PF17661.1 CDJ57585.1 - 1.3 8.7 29.8 0.097 12.3 5.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) PCNP PF15473.6 CDJ57585.1 - 1.5 9.5 11.2 5.4 7.7 0.6 2.1 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family YABBY PF04690.13 CDJ57585.1 - 1.5 9.3 14.8 2.7 8.6 0.6 2.1 2 0 0 2 2 2 0 YABBY protein PPL5 PF18168.1 CDJ57585.1 - 1.7 7.9 15.8 0.15 11.3 0.8 2.1 2 0 0 2 2 2 0 Prim-pol family 5 Eapp_C PF10238.9 CDJ57585.1 - 1.8 8.7 25.0 2.2 8.4 5.7 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein ATP11 PF06644.11 CDJ57585.1 - 1.9 8.2 22.8 2.7 7.7 4.3 2.1 2 0 0 2 2 2 0 ATP11 protein U1snRNP70_N PF12220.8 CDJ57585.1 - 1.9 9.2 25.0 1.3 9.7 6.0 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4820 PF16091.5 CDJ57585.1 - 1.9 7.8 18.5 1.3 8.3 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) EFTUD2 PF16004.5 CDJ57585.1 - 1.9 9.1 26.7 3.6 8.2 6.7 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Dynamin_N PF00350.23 CDJ57585.1 - 2 8.4 11.9 1.9 8.5 2.2 2.1 2 0 0 2 2 2 0 Dynamin family Peptidase_U57 PF05582.12 CDJ57585.1 - 2.1 7.6 13.3 0.33 10.2 2.2 2.1 2 0 0 2 2 2 0 YabG peptidase U57 RBM39linker PF15519.6 CDJ57585.1 - 2.1 9.5 18.9 8.9 7.5 2.1 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Maf1 PF09174.10 CDJ57585.1 - 2.1 8.5 10.8 6.1 7.0 0.9 2.1 2 0 0 2 2 2 0 Maf1 regulator DUF4518 PF15008.6 CDJ57585.1 - 2.5 7.2 20.9 0.19 10.8 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Peptidase_C58 PF03543.14 CDJ57585.1 - 2.6 7.7 21.5 0.49 10.1 8.5 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen MAS20 PF02064.15 CDJ57585.1 - 2.6 8.1 27.4 0.67 10.1 6.4 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor TFB6 PF17110.5 CDJ57585.1 - 2.6 7.8 18.9 3.6 7.3 3.1 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF4484 PF14831.6 CDJ57585.1 - 2.6 8.0 19.0 1.2 9.1 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF5427 PF10310.9 CDJ57585.1 - 2.7 6.9 24.9 0.99 8.3 8.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Mak16 PF04874.14 CDJ57585.1 - 2.7 8.7 24.0 2.4 8.8 6.8 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region Het-C PF07217.11 CDJ57585.1 - 2.7 6.4 13.1 2.8 6.3 2.7 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C RMP PF14996.6 CDJ57585.1 - 2.9 8.1 14.8 4 7.6 4.2 2.1 2 0 0 2 2 2 0 Retinal Maintenance Slu7 PF11708.8 CDJ57585.1 - 2.9 7.6 23.1 1.1 8.9 4.1 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF1980 PF09323.10 CDJ57585.1 - 3.2 7.6 14.7 2.8 7.8 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4637 PF15470.6 CDJ57585.1 - 3.4 7.4 23.2 0.47 10.2 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) GCD14 PF08704.10 CDJ57585.1 - 3.4 7.3 8.7 2.5 7.7 2.5 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF4770 PF15994.5 CDJ57585.1 - 3.6 7.8 26.8 1.6 8.9 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF868 PF05910.12 CDJ57585.1 - 3.6 7.1 10.5 3.2 7.3 1.4 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF868) Folate_carrier PF01770.18 CDJ57585.1 - 3.6 6.2 13.2 3.5 6.3 4.4 2.0 2 0 0 2 2 2 0 Reduced folate carrier LMBR1 PF04791.16 CDJ57585.1 - 3.9 6.3 9.8 5.2 5.8 9.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CRF1 PF10380.9 CDJ57585.1 - 3.9 7.8 12.0 6.2 7.2 2.8 2.2 2 0 0 2 2 2 0 Transcription factor CRF1 PA26 PF04636.13 CDJ57585.1 - 4.1 6.2 17.2 2.1 7.2 3.4 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) PcfK PF14058.6 CDJ57585.1 - 4.4 7.6 25.4 1.2 9.4 3.8 2.3 2 0 0 2 2 2 0 PcfK-like protein DUF3408 PF11888.8 CDJ57585.1 - 4.5 7.4 29.0 3.1 7.9 8.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1754 PF08555.10 CDJ57585.1 - 5.2 7.9 26.5 1 10.2 8.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.14 CDJ57585.1 - 5.2 5.2 21.1 3 6.0 4.5 2.0 2 0 0 2 2 2 0 CDC45-like protein CSRNP_N PF16019.5 CDJ57585.1 - 5.3 6.9 20.9 0.75 9.7 3.3 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Usp PF00582.26 CDJ57585.1 - 5.4 7.5 12.3 0.92 10.0 0.8 2.3 2 0 0 2 2 2 0 Universal stress protein family RXT2_N PF08595.11 CDJ57585.1 - 5.5 7.0 20.7 1.9 8.5 3.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4337 PF14235.6 CDJ57585.1 - 5.6 7.1 18.1 3.8 7.6 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Rtf2 PF04641.12 CDJ57585.1 - 6.1 6.1 19.7 5.8 6.2 4.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger MAM33 PF02330.16 CDJ57585.1 - 6.2 6.7 25.8 4.4 7.2 8.4 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein XRN_N PF03159.18 CDJ57585.1 - 6.2 6.2 14.0 2.8 7.3 4.7 2.1 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus CTU2 PF10288.9 CDJ57585.1 - 6.8 7.0 21.9 9.6 6.5 5.4 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4746 PF15928.5 CDJ57585.1 - 7.3 5.9 22.1 5.8 6.2 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RabGAP-TBC PF00566.18 CDJ57585.1 - 7.3 6.2 16.9 5 6.7 4.6 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Pal1 PF08316.11 CDJ57585.1 - 7.9 7.2 10.3 9.7 6.9 2.8 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF3506 PF12014.8 CDJ57585.1 - 8 6.5 10.2 7.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Afi1 PF07792.12 CDJ57585.1 - 8.5 6.9 24.1 2.9 8.4 4.2 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sec62 PF03839.16 CDJ57585.1 - 9 5.7 18.1 7.8 5.9 7.2 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF1764 PF08576.10 CDJ57585.1 - 9 7.3 23.9 15 6.6 6.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) tRNA_synt_1c_R2 PF04557.15 CDJ57585.1 - 9.2 7.3 20.7 11 7.0 5.7 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RAB3GAP2_C PF14656.6 CDJ57585.1 - 9.4 4.3 17.0 4.5 5.4 6.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus PPP4R2 PF09184.11 CDJ57586.1 - 0.78 9.3 5.4 1.2 8.7 5.4 1.3 1 0 0 1 1 1 0 PPP4R2 MRP-S31 PF15433.6 CDJ57586.1 - 1 9.0 22.4 0.05 13.3 15.4 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 RAP1 PF07218.11 CDJ57586.1 - 1.5 7.0 8.0 2 6.6 8.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4559 PF15112.6 CDJ57586.1 - 3 7.4 13.6 0.57 9.8 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) AF-4 PF05110.13 CDJ57586.1 - 4.2 5.3 34.3 16 3.4 34.8 1.6 1 1 1 2 2 2 0 AF-4 proto-oncoprotein ExbD PF02472.16 CDJ57586.1 - 4.7 7.4 8.4 30 4.8 4.1 2.7 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DUF3446 PF11928.8 CDJ57586.1 - 5.1 7.5 23.3 2.5 8.5 10.7 3.7 4 0 0 4 4 4 0 Early growth response N-terminal domain FHA PF00498.26 CDJ57587.1 - 0.00031 21.1 0.0 0.0038 17.6 0.0 2.4 2 0 0 2 2 2 1 FHA domain SR-25 PF10500.9 CDJ57587.1 - 0.055 13.1 42.5 0.051 13.2 7.2 4.1 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Hemerythrin PF01814.23 CDJ57587.1 - 0.33 11.6 7.7 1.5 9.4 7.7 2.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain RskA PF10099.9 CDJ57588.1 - 0.0021 18.4 11.0 0.0021 18.4 11.0 5.0 1 1 2 4 4 4 2 Anti-sigma-K factor rskA Cyt_bd_oxida_II PF02322.15 CDJ57588.1 - 0.6 9.4 6.0 0.25 10.6 1.0 2.1 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II RskA PF10099.9 CDJ57589.1 - 0.0027 18.0 10.9 0.0027 18.0 10.9 5.2 1 1 3 4 4 4 2 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ57589.1 - 8.6 6.0 30.8 1.8 8.2 17.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) Presenilin PF01080.17 CDJ57590.1 - 0.34 9.6 24.6 0.44 9.2 24.6 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 CDJ57590.1 - 0.39 9.7 16.6 0.42 9.5 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 CDJ57590.1 - 1.4 8.2 9.1 1.2 8.4 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SDA1 PF05285.12 CDJ57590.1 - 4.6 6.6 26.6 0.37 10.2 1.0 2.2 2 0 0 2 2 2 0 SDA1 DUF2722 PF10846.8 CDJ57591.1 - 7.1e-05 21.9 9.2 0.00024 20.2 2.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) BCAS2 PF05700.11 CDJ57591.1 - 0.00062 19.5 0.9 0.0011 18.7 0.9 1.4 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) RskA PF10099.9 CDJ57591.1 - 0.0077 16.5 20.8 0.14 12.4 1.6 3.3 3 0 0 3 3 3 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ57591.1 - 0.017 14.8 20.3 0.031 13.9 11.4 2.1 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ57591.1 - 0.31 9.8 3.8 0.5 9.1 3.8 1.2 1 0 0 1 1 1 0 Presenilin GTA_holin_3TM PF11351.8 CDJ57591.1 - 0.38 11.3 9.5 0.07 13.7 4.2 2.1 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release CCDC53 PF10152.9 CDJ57591.1 - 1 9.7 8.9 10 6.6 0.7 2.9 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF4834 PF16118.5 CDJ57591.1 - 2.3 9.3 9.4 0.52 11.3 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 CDJ57591.1 - 3.7 8.5 25.9 0.56 11.1 11.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 IMUP PF15761.5 CDJ57591.1 - 3.7 8.3 10.3 2.6 8.8 0.6 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein TERB2 PF15101.6 CDJ57591.1 - 4.8 7.2 11.4 8.4 6.4 5.2 2.9 3 0 0 3 3 3 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 CDJ57591.1 - 5.8 7.6 19.3 1.2 9.8 2.9 3.0 4 0 0 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1840 PF08895.11 CDJ57591.1 - 7.9 6.9 10.7 1.7 9.0 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Coilin_N PF15862.5 CDJ57591.1 - 8.7 6.2 10.0 2 8.2 1.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus Mlo PF03094.15 CDJ57592.1 - 3e-08 32.5 5.0 3.3e-07 29.1 1.2 2.7 2 1 0 3 3 3 1 Mlo family EF-hand_7 PF13499.6 CDJ57592.1 - 0.00087 19.7 0.0 0.0033 17.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ57592.1 - 0.0017 18.1 0.2 0.0063 16.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDJ57592.1 - 0.017 14.6 0.4 0.089 12.4 0.1 2.3 2 0 0 2 2 2 0 EF hand YniB PF14002.6 CDJ57592.1 - 0.032 14.0 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 YniB-like protein Baculo_11_kDa PF06143.11 CDJ57592.1 - 0.24 11.0 0.1 0.24 11.0 0.1 3.0 4 0 0 4 4 4 0 Baculovirus 11 kDa family COX2_TM PF02790.15 CDJ57592.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain PIG-P PF08510.12 CDJ57592.1 - 3.7 7.5 8.0 0.31 11.0 0.4 2.8 2 2 0 2 2 2 0 PIG-P JmjC PF02373.22 CDJ57593.1 - 8.6e-23 80.9 0.2 1.6e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDJ57593.1 - 3.2e-21 76.2 0.3 9.7e-21 74.6 0.1 1.8 1 1 1 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 CDJ57593.1 - 0.00037 20.1 0.0 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein SR-25 PF10500.9 CDJ57593.1 - 0.013 15.1 6.6 0.013 15.1 6.6 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GPI PF06560.11 CDJ57593.1 - 0.062 12.6 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 CDJ57593.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain L51_S25_CI-B8 PF05047.16 CDJ57593.1 - 0.096 12.6 0.8 0.44 10.5 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain IMUP PF15761.5 CDJ57593.1 - 7.2 7.4 12.0 0.6 10.8 6.8 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Ribosomal_L16 PF00252.18 CDJ57594.1 - 4.4e-09 36.4 0.1 2.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L16p/L10e SAS4 PF15460.6 CDJ57596.1 - 5.6 7.1 8.2 1.1 9.5 0.1 3.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 PSII PF00421.19 CDJ57597.1 - 0.27 9.8 0.8 0.34 9.5 0.8 1.0 1 0 0 1 1 1 0 Photosystem II protein zf-CCCH PF00642.24 CDJ57598.1 - 1.1e-10 41.2 13.7 2.1e-05 24.3 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ57598.1 - 4.6e-05 23.3 15.9 0.011 15.7 5.7 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CDJ57598.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CDJ57598.1 - 0.00076 20.2 5.4 0.2 12.4 1.0 2.6 2 1 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CDJ57598.1 - 1.5 8.7 16.2 3.2 7.7 6.6 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger RabGAP-TBC PF00566.18 CDJ57599.1 - 5.7e-21 75.2 3.8 5.7e-21 75.2 3.8 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CDJ57599.1 - 1.2e-13 51.0 0.0 2.2e-07 30.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57599.1 - 1.2e-07 31.3 0.0 5.3e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Rhodanese PF00581.20 CDJ57599.1 - 0.0036 17.8 0.0 1.3 9.6 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Kinase-like PF14531.6 CDJ57599.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ras PF00071.22 CDJ57602.1 - 2.9e-46 157.0 0.1 2.4e-45 154.0 0.1 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ57602.1 - 7.4e-33 113.3 0.0 1.4e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ57602.1 - 9.9e-14 51.2 0.0 2.3e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ57602.1 - 3.7e-09 36.4 0.0 5.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ57602.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ57602.1 - 0.00056 19.9 1.2 0.12 12.3 0.1 3.0 2 1 1 3 3 3 1 RsgA GTPase TRAPPC-Trs85 PF12739.7 CDJ57602.1 - 0.0013 17.7 0.3 0.0018 17.4 0.3 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ATP_bind_1 PF03029.17 CDJ57602.1 - 0.0087 15.9 0.0 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDJ57602.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CDJ57602.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ57602.1 - 0.034 14.4 0.1 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ57602.1 - 0.035 14.6 0.3 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 CDJ57602.1 - 0.051 14.0 6.3 0.65 10.4 6.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain Sigma70_ner PF04546.13 CDJ57602.1 - 0.077 12.9 1.5 0.11 12.4 1.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Hpr_kinase_C PF07475.12 CDJ57602.1 - 0.13 11.8 0.1 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain G-alpha PF00503.20 CDJ57602.1 - 0.19 10.8 1.6 2.8 7.0 1.6 2.7 1 1 0 1 1 1 0 G-protein alpha subunit Spt20 PF12090.8 CDJ57602.1 - 0.33 10.5 7.2 0.49 10.0 7.2 1.2 1 0 0 1 1 1 0 Spt20 family Siah-Interact_N PF09032.11 CDJ57602.1 - 0.57 10.5 4.7 6.8 7.1 5.4 2.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal Roughex PF06020.11 CDJ57602.1 - 0.73 8.9 5.7 0.99 8.4 5.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SPAN PF02510.14 CDJ57602.1 - 6.1 5.9 8.8 10 5.2 8.8 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein Syja_N PF02383.18 CDJ57603.1 - 1.1e-35 123.5 0.0 1.4e-16 60.7 0.0 3.8 2 2 0 2 2 2 2 SacI homology domain DUF3042 PF11240.8 CDJ57603.1 - 0.25 11.4 0.0 0.25 11.4 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3042) SPX PF03105.19 CDJ57603.1 - 0.35 10.7 16.7 2.6 7.9 0.4 3.8 3 1 0 3 3 3 0 SPX domain Filamin PF00630.19 CDJ57605.1 - 2.5e-06 28.3 3.2 2.5e-06 28.3 3.2 2.9 2 1 0 2 2 2 1 Filamin/ABP280 repeat SR-25 PF10500.9 CDJ57605.1 - 0.00085 19.0 9.3 0.00085 19.0 9.3 4.2 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ57605.1 - 0.0032 17.4 19.3 0.0032 17.4 19.3 2.2 2 0 0 2 2 2 1 SPX domain DUF349 PF03993.12 CDJ57605.1 - 0.023 15.0 9.7 0.023 15.0 9.7 4.5 3 1 2 5 5 5 0 Domain of Unknown Function (DUF349) RR_TM4-6 PF06459.12 CDJ57605.1 - 1.7 8.4 42.3 1.2 8.9 19.4 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 CDJ57605.1 - 5.8 7.3 31.7 1.5 9.3 15.9 3.2 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PAP1 PF08601.10 CDJ57606.1 - 0.00012 21.9 0.0 0.00012 21.9 0.0 11.2 9 4 2 11 11 11 1 Transcription factor PAP1 RskA PF10099.9 CDJ57606.1 - 0.0005 20.4 1.1 0.0005 20.4 1.1 23.3 5 3 11 17 17 17 4 Anti-sigma-K factor rskA PTPRCAP PF15713.5 CDJ57606.1 - 0.75 10.1 0.0 0.75 10.1 0.0 11.8 8 4 1 9 9 9 0 Protein tyrosine phosphatase receptor type C-associated SR-25 PF10500.9 CDJ57608.1 - 1.3 8.6 16.0 0.2 11.2 10.1 2.3 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Rad1 PF02144.16 CDJ57610.1 - 0.00018 20.7 1.6 0.0074 15.4 0.1 2.2 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 SUIM_assoc PF16619.5 CDJ57610.1 - 0.012 15.7 6.7 0.012 15.7 6.7 3.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ57610.1 - 0.02 15.5 2.5 3.9 8.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) MID_MedPIWI PF18296.1 CDJ57610.1 - 0.034 13.9 2.2 4.7 6.9 1.1 2.3 2 0 0 2 2 2 0 MID domain of medPIWI IMUP PF15761.5 CDJ57610.1 - 0.76 10.5 17.0 0.14 12.8 3.7 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein YajC PF02699.15 CDJ57610.1 - 10 6.1 8.7 4.6 7.2 2.1 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit P_proprotein PF01483.20 CDJ57611.1 - 0.32 11.1 5.0 0.15 12.1 0.5 2.7 2 1 1 3 3 3 0 Proprotein convertase P-domain DUF2434 PF10361.9 CDJ57611.1 - 0.37 9.7 4.3 0.75 8.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) SR-25 PF10500.9 CDJ57612.1 - 0.01 15.5 20.7 0.013 15.1 20.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 CDJ57612.1 - 0.56 10.1 7.5 0.7 9.7 7.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family IQCJ-SCHIP1 PF15157.6 CDJ57612.1 - 0.9 9.4 5.3 0.98 9.3 5.3 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF1635 PF07795.11 CDJ57612.1 - 1.1 9.0 5.3 1.2 9.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Lin-8 PF03353.15 CDJ57612.1 - 1.8 8.1 3.2 2 7.9 3.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ57612.1 - 2.3 7.0 6.1 2.3 7.0 6.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF515 PF04415.12 CDJ57612.1 - 3.3 6.0 12.1 3.3 6.0 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CCDC106 PF15794.5 CDJ57612.1 - 4.1 7.0 8.0 4.8 6.8 8.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDJ57612.1 - 4.2 5.8 11.3 4.4 5.8 11.3 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CDJ57612.1 - 8.7 5.2 9.5 9.1 5.1 9.5 1.0 1 0 0 1 1 1 0 Mitoguardin GREB1 PF15782.5 CDJ57612.1 - 9.3 3.2 6.0 9.5 3.2 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ57613.1 - 0.011 15.3 3.9 0.011 15.3 3.9 2.9 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DUF2716 PF10898.8 CDJ57613.1 - 0.24 11.8 0.2 0.24 11.8 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2716) FAM176 PF14851.6 CDJ57613.1 - 0.31 10.7 8.9 1.2 8.8 0.5 3.3 3 0 0 3 3 3 0 FAM176 family MatP_C PF17414.2 CDJ57614.1 - 7.3 6.9 8.9 22 5.4 0.5 4.4 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Macoilin PF09726.9 CDJ57617.1 - 0.64 8.5 9.7 0.83 8.1 9.7 1.2 1 0 0 1 1 1 0 Macoilin family RskA PF10099.9 CDJ57620.1 - 0.0014 18.9 49.9 0.014 15.7 0.4 4.4 1 1 3 4 4 4 2 Anti-sigma-K factor rskA Afi1 PF07792.12 CDJ57620.1 - 0.01 16.4 1.4 0.01 16.4 1.4 4.2 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking TMEM214 PF10151.9 CDJ57620.1 - 0.024 13.1 0.4 0.024 13.1 0.4 3.6 2 1 1 3 3 3 0 TMEM214, C-terminal, caspase 4 activator DUF2722 PF10846.8 CDJ57621.1 - 0.00016 20.7 2.9 0.00016 20.7 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ57621.1 - 0.023 14.7 9.6 0.027 14.5 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ57621.1 - 0.027 14.1 12.1 0.035 13.7 12.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF1180 PF06679.12 CDJ57621.1 - 0.16 12.4 2.1 0.26 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ndc1_Nup PF09531.10 CDJ57621.1 - 0.2 10.3 1.3 0.24 10.1 1.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 CDJ57621.1 - 0.31 11.0 5.2 0.38 10.7 5.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ57621.1 - 1.2 8.0 19.9 1.6 7.6 19.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.15 CDJ57621.1 - 1.4 8.7 10.7 1.1 9.1 8.8 1.7 2 0 0 2 2 2 0 Septum formation initiator cNMP_binding PF00027.29 CDJ57623.1 - 2.9e-11 43.3 1.6 2.5e-06 27.5 0.0 4.0 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain RskA PF10099.9 CDJ57623.1 - 0.004 17.5 12.5 0.004 17.5 12.5 16.4 4 4 10 14 14 14 4 Anti-sigma-K factor rskA DUF1754 PF08555.10 CDJ57623.1 - 0.013 16.3 12.1 0.013 16.3 12.1 12.5 9 1 0 9 9 9 0 Eukaryotic family of unknown function (DUF1754) Kelch_4 PF13418.6 CDJ57624.1 - 6.7e-36 122.1 5.1 3.8e-06 26.8 0.1 6.9 5 2 2 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ57624.1 - 3.6e-28 97.3 0.5 6.9e-06 26.2 0.0 7.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ57624.1 - 1e-26 92.3 1.6 0.00054 20.2 0.3 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 CDJ57624.1 - 2.2e-22 78.6 0.0 0.00016 21.6 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDJ57624.1 - 1.3e-15 56.7 6.2 0.0084 15.7 0.2 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CDJ57624.1 - 8.6e-14 50.9 5.8 0.015 15.2 0.0 7.5 7 1 0 7 7 7 3 Kelch motif RskA PF10099.9 CDJ57624.1 - 0.015 15.6 7.5 0.015 15.6 5.6 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ57624.1 - 0.092 12.2 2.7 0.13 11.7 2.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hamartin PF04388.12 CDJ57624.1 - 0.31 9.6 6.0 0.39 9.3 6.0 1.1 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 CDJ57624.1 - 0.39 10.6 6.2 0.57 10.1 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.22 CDJ57624.1 - 0.67 9.1 1.7 0.9 8.7 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Roughex PF06020.11 CDJ57624.1 - 1.2 8.1 8.8 6.8 5.7 7.7 2.0 2 0 0 2 2 2 0 Drosophila roughex protein V_ATPase_I PF01496.19 CDJ57624.1 - 2 6.2 3.6 2.8 5.7 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 CDJ57624.1 - 2.6 7.0 4.8 3.6 6.5 4.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 CDJ57624.1 - 3.1 6.0 5.9 4.5 5.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein IHABP4_N PF16174.5 CDJ57624.1 - 3.8 8.1 17.9 8.2 7.0 17.9 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal ORC6 PF05460.13 CDJ57624.1 - 4.3 6.5 13.2 7.3 5.8 13.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF5427 PF10310.9 CDJ57624.1 - 6.8 5.5 20.2 9 5.1 20.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 CDJ57624.1 - 7.1 5.3 10.1 9.7 4.8 10.1 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ57624.1 - 7.9 5.0 7.8 9.9 4.7 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.6 CDJ57624.1 - 9.5 5.9 6.5 16 5.1 6.5 1.3 1 0 0 1 1 1 0 FAM176 family EF-hand_7 PF13499.6 CDJ57626.1 - 5.4e-21 74.8 5.4 2.2e-08 34.4 0.1 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ57626.1 - 1.5e-13 49.2 9.8 0.00014 21.2 0.1 5.7 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 CDJ57626.1 - 2e-13 49.1 8.8 0.0034 17.2 0.2 5.3 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 CDJ57626.1 - 1.3e-12 47.3 5.8 7.1e-06 25.8 0.1 5.0 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ57626.1 - 5.2e-05 22.5 2.9 0.013 15.0 0.1 4.8 4 0 0 4 4 4 1 EF hand SpoIIAA-like PF11964.8 CDJ57626.1 - 0.098 13.7 0.2 0.85 10.7 0.1 2.4 2 1 0 2 2 2 0 SpoIIAA-like PI3K_1B_p101 PF10486.9 CDJ57626.1 - 0.43 8.3 4.8 0.56 7.9 4.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pyr_redox_2 PF07992.14 CDJ57627.1 - 4.4e-41 141.0 0.0 6.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ57627.1 - 3e-23 82.2 0.5 2.4e-14 53.5 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ57627.1 - 1.3e-15 57.7 4.1 5.3e-12 46.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ57627.1 - 5.1e-09 35.8 1.5 1.5e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDJ57627.1 - 1.8e-07 30.9 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ57627.1 - 1.7e-06 27.4 2.7 0.018 14.1 2.6 2.5 1 1 1 2 2 2 2 FAD binding domain GIDA PF01134.22 CDJ57627.1 - 8e-06 25.2 3.3 3.2e-05 23.2 1.9 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 CDJ57627.1 - 0.0004 19.6 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CDJ57627.1 - 0.0038 16.0 1.1 0.077 11.7 0.7 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CDJ57627.1 - 0.0038 16.5 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 CDJ57627.1 - 0.0047 16.3 1.5 2.9 7.2 0.0 2.8 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 CDJ57627.1 - 0.0073 15.9 3.6 0.3 10.6 2.4 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ57627.1 - 0.028 14.6 0.3 0.028 14.6 0.3 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDJ57627.1 - 0.034 13.2 0.7 0.065 12.3 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 CDJ57627.1 - 0.041 14.3 0.3 0.85 10.1 0.1 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.6 CDJ57627.1 - 0.046 14.2 0.0 6.1 7.4 0.0 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 CDJ57627.1 - 0.05 12.9 1.1 3.4 6.9 0.5 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 CDJ57627.1 - 0.06 12.8 0.2 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 CDJ57627.1 - 0.065 13.1 3.2 0.53 10.1 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDJ57627.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CDJ57627.1 - 0.29 11.1 3.3 0.24 11.4 0.3 2.2 2 1 0 2 2 1 0 FAD-NAD(P)-binding YABBY PF04690.13 CDJ57628.1 - 4.7 7.8 0.0 4.7 7.8 0.0 3.8 2 1 0 3 3 3 0 YABBY protein Peptidase_M22 PF00814.25 CDJ57629.1 - 8.5e-22 78.1 5.8 3.1e-16 59.9 0.1 4.0 4 1 0 4 4 4 3 Glycoprotease family mRNA_triPase PF02940.15 CDJ57630.1 - 1.8e-10 40.9 0.0 0.0016 18.2 0.0 3.1 2 1 0 2 2 2 2 mRNA capping enzyme, beta chain LMBR1 PF04791.16 CDJ57631.1 - 7.1 5.4 10.2 9.9 4.9 10.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Patatin PF01734.22 CDJ57632.1 - 0.0019 18.4 4.0 0.0066 16.6 4.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.6 CDJ57633.1 - 1.1e-06 29.1 3.4 1.1e-06 29.1 3.4 3.4 3 1 0 3 3 3 1 AAA ATPase domain ORC4_C PF14629.6 CDJ57633.1 - 0.00034 20.0 0.1 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.6 CDJ57633.1 - 0.00036 20.8 2.9 0.00039 20.7 0.6 2.3 2 0 0 2 2 2 1 AAA domain IMUP PF15761.5 CDJ57633.1 - 0.041 14.6 0.2 0.041 14.6 0.2 3.4 3 0 0 3 3 3 0 Immortalisation up-regulated protein T2SSE PF00437.20 CDJ57633.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 CDJ57633.1 - 0.05 13.0 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_3 PF01171.20 CDJ57633.1 - 0.75 9.5 6.1 0.1 12.3 0.7 2.2 3 0 0 3 3 3 0 PP-loop family Activator_LAG-3 PF11498.8 CDJ57634.1 - 0.00098 18.2 7.2 0.00098 18.2 7.2 3.9 3 1 0 3 3 3 1 Transcriptional activator LAG-3 RabGGT_insert PF07711.11 CDJ57634.1 - 2.3 8.7 5.1 3.9 8.0 4.0 1.8 2 0 0 2 2 2 0 Rab geranylgeranyl transferase alpha-subunit, insert domain AP2 PF00847.20 CDJ57635.1 - 3.7e-05 23.9 2.1 3.7e-05 23.9 2.1 3.6 2 0 0 2 2 2 1 AP2 domain SR-25 PF10500.9 CDJ57636.1 - 0.004 16.8 20.1 0.004 16.8 20.1 7.9 4 2 5 9 9 9 1 Nuclear RNA-splicing-associated protein AbrB PF05145.12 CDJ57637.1 - 0.0042 16.1 1.9 0.018 14.0 0.5 2.4 2 0 0 2 2 2 1 Transition state regulatory protein AbrB SUIM_assoc PF16619.5 CDJ57638.1 - 0.015 15.4 5.6 0.015 15.4 5.6 14.5 11 3 1 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 Fer2 PF00111.27 CDJ57640.1 - 3.7e-12 46.0 5.1 4.8e-12 45.7 5.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 CDJ57640.1 - 0.16 12.0 1.4 0.59 10.2 1.3 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain P34-Arc PF04045.14 CDJ57641.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc VPS9 PF02204.18 CDJ57642.1 - 0.0065 16.7 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Exonuc_VII_L PF02601.15 CDJ57643.1 - 0.011 15.3 1.4 0.011 15.3 1.4 3.3 3 0 0 3 3 3 0 Exonuclease VII, large subunit TFIIF_alpha PF05793.12 CDJ57643.1 - 1.2 7.6 24.1 2.5 6.6 24.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1664 PF07889.12 CDJ57645.1 - 0.016 15.3 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RskA PF10099.9 CDJ57645.1 - 0.041 14.2 7.3 0.042 14.1 2.2 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3175 PF11373.8 CDJ57647.1 - 0.2 11.8 6.3 0.059 13.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) Bac_GDH PF05088.12 CDJ57647.1 - 0.98 6.8 27.3 1.6 6.1 27.3 1.4 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase PP2C PF00481.21 CDJ57649.1 - 8.5e-18 64.9 3.8 8.5e-18 64.9 3.8 5.1 4 2 1 5 5 5 2 Protein phosphatase 2C TFIIA PF03153.13 CDJ57649.1 - 0.013 15.5 154.0 0.019 15.0 30.9 4.7 3 1 1 4 4 4 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 CDJ57651.1 - 0.0058 15.2 3.5 0.007 14.9 3.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Secretin_N_2 PF07655.13 CDJ57651.1 - 0.0061 17.1 1.5 1.1 9.8 0.1 2.3 2 0 0 2 2 2 2 Secretin N-terminal domain LMBR1 PF04791.16 CDJ57651.1 - 0.015 14.2 1.5 0.018 13.9 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SARAF PF06682.12 CDJ57651.1 - 0.041 13.5 0.7 0.06 13.0 0.2 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CDC13_N PF16853.5 CDJ57651.1 - 0.14 11.6 2.5 0.2 11.2 2.5 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus CCSAP PF15748.5 CDJ57651.1 - 0.16 12.1 3.3 0.22 11.7 3.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated OmpH PF03938.14 CDJ57651.1 - 0.46 10.8 16.0 0.73 10.2 13.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.16 CDJ57652.1 - 0.00043 19.3 2.7 0.00043 19.3 2.7 2.1 2 0 0 2 2 2 1 LMBR1-like membrane protein Chitin_synth_1 PF01644.17 CDJ57652.1 - 0.73 9.8 11.0 1.1 9.2 11.0 1.2 1 0 0 1 1 1 0 Chitin synthase IL31 PF15209.6 CDJ57652.1 - 2.5 7.9 12.1 0.043 13.6 3.5 2.1 1 1 1 2 2 2 0 Interleukin 31 V-ATPase_H_N PF03224.14 CDJ57653.1 - 1.7e-21 76.8 0.5 4.4e-18 65.6 0.2 2.4 3 0 0 3 3 3 2 V-ATPase subunit H SR-25 PF10500.9 CDJ57654.1 - 0.01 15.5 15.5 0.01 15.5 15.5 5.6 2 1 3 5 5 5 0 Nuclear RNA-splicing-associated protein tRNA_NucTransf2 PF09249.11 CDJ57654.1 - 0.46 10.8 3.4 0.61 10.4 0.1 2.6 3 0 0 3 3 3 0 tRNA nucleotidyltransferase, second domain U1snRNP70_N PF12220.8 CDJ57654.1 - 1.3 9.7 26.1 1.8 9.3 0.5 3.6 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Radial_spoke_3 PF06098.11 CDJ57654.1 - 9.2 5.4 37.3 0.53 9.5 3.5 3.3 3 0 0 3 3 3 0 Radial spoke protein 3 BSP_II PF05432.11 CDJ57655.1 - 9.5e-06 25.5 3.2 9.5e-06 25.5 3.2 2.4 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) RskA PF10099.9 CDJ57655.1 - 0.002 18.5 1.6 0.002 18.5 1.6 5.4 2 2 1 3 3 2 1 Anti-sigma-K factor rskA BUD22 PF09073.10 CDJ57655.1 - 0.0061 16.0 0.4 0.0061 16.0 0.4 2.5 2 2 0 2 2 1 1 BUD22 DUF4834 PF16118.5 CDJ57655.1 - 0.015 16.3 0.4 0.015 16.3 0.4 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 CDJ57655.1 - 0.02 14.8 1.5 0.02 14.8 1.5 3.9 4 0 0 4 4 4 0 Myc amino-terminal region SPX PF03105.19 CDJ57655.1 - 0.053 13.4 24.5 0.33 10.8 4.5 2.5 2 1 0 2 2 2 0 SPX domain RRP36 PF06102.12 CDJ57655.1 - 1.4 8.8 10.3 3.1 7.8 10.3 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 CDC45 PF02724.14 CDJ57655.1 - 2.9 6.1 8.3 0.38 9.0 0.8 2.2 2 0 0 2 2 2 0 CDC45-like protein Chorion_2 PF03964.15 CDJ57655.1 - 4.5 8.2 0.0 4.5 8.2 0.0 9.1 4 2 4 9 9 6 0 Chorion family 2 DUF2052 PF09747.9 CDJ57655.1 - 5.5 7.1 17.6 0.025 14.7 6.7 2.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 CDJ57655.1 - 5.6 5.6 21.2 31 3.2 18.5 2.5 2 1 0 2 2 2 0 Presenilin RED_N PF07808.13 CDJ57655.1 - 5.8 6.4 11.2 19 4.8 11.2 1.8 1 0 0 1 1 1 0 RED-like protein N-terminal region EcsC PF12787.7 CDJ57655.1 - 6.1 6.4 16.1 5.3 6.6 2.0 3.6 3 0 0 3 3 3 0 EcsC protein family zf-RING_2 PF13639.6 CDJ57656.1 - 1.4e-10 41.3 3.2 2.9e-10 40.3 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDJ57656.1 - 4.5e-08 32.8 1.5 9.2e-08 31.8 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ57656.1 - 8.2e-08 32.4 2.3 2.9e-07 30.7 2.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDJ57656.1 - 2.2e-06 27.6 1.7 4e-06 26.7 0.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ57656.1 - 5.8e-06 26.2 2.0 1.1e-05 25.3 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ57656.1 - 6.7e-06 25.8 1.8 1.4e-05 24.8 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ57656.1 - 9.2e-06 25.4 3.6 1.5e-05 24.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ57656.1 - 5.3e-05 23.2 1.9 0.00011 22.1 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDJ57656.1 - 0.00013 21.6 3.0 0.00013 21.6 3.0 2.4 3 0 0 3 3 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CDJ57656.1 - 0.002 17.7 3.8 0.0037 16.9 3.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ57656.1 - 0.0085 15.9 6.5 0.018 14.9 6.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDJ57656.1 - 0.025 14.7 3.6 0.063 13.4 3.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 CDJ57656.1 - 0.12 12.6 6.4 0.053 13.7 3.7 1.9 2 0 0 2 2 2 0 RING-variant domain RNA_Me_trans PF04252.13 CDJ57656.1 - 0.21 11.2 3.4 0.1 12.2 0.2 2.1 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase FANCL_C PF11793.8 CDJ57656.1 - 0.58 10.4 2.2 1.5 9.1 2.2 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 CDJ57656.1 - 0.92 9.9 3.4 1.8 8.9 3.4 1.5 1 0 0 1 1 1 0 RING-like domain TFIIF_alpha PF05793.12 CDJ57657.1 - 9e-05 21.3 13.6 9e-05 21.3 13.6 3.5 3 0 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SIR2 PF02146.17 CDJ57657.1 - 0.0019 18.1 16.8 0.025 14.5 0.0 4.1 3 1 1 5 5 5 2 Sir2 family DUF2722 PF10846.8 CDJ57657.1 - 0.002 17.1 0.7 0.002 17.1 0.7 6.8 6 1 1 7 7 7 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ57657.1 - 0.0021 18.4 11.7 0.0021 18.4 11.7 10.0 2 2 2 4 4 4 1 Anti-sigma-K factor rskA CPSF100_C PF13299.6 CDJ57657.1 - 0.0097 16.1 8.3 0.0097 16.1 8.3 5.2 6 0 0 6 6 6 2 Cleavage and polyadenylation factor 2 C-terminal Pes-10 PF07149.11 CDJ57657.1 - 2 7.4 15.7 4 6.4 15.7 1.4 1 0 0 1 1 1 0 Pes-10 Presenilin PF01080.17 CDJ57657.1 - 2.8 6.6 53.5 0.65 8.7 8.7 4.2 4 0 0 4 4 4 0 Presenilin Spt20 PF12090.8 CDJ57658.1 - 0.00024 20.8 16.8 0.00024 20.8 16.8 9.3 4 2 4 8 8 8 2 Spt20 family Sod_Fe_C PF02777.18 CDJ57659.1 - 1.7e-25 89.1 0.1 2.3e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain CTXphi_pIII-N1 PF16710.5 CDJ57659.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII SPX PF03105.19 CDJ57660.1 - 0.072 13.0 0.1 0.072 13.0 0.1 4.6 1 1 2 4 4 4 0 SPX domain Pkinase PF00069.25 CDJ57661.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 CDJ57663.1 - 3.9e-10 39.7 1.0 1.2e-06 28.2 1.2 2.6 2 1 0 2 2 2 2 Choline/ethanolamine kinase SR-25 PF10500.9 CDJ57663.1 - 0.00062 19.5 17.9 0.00062 19.5 17.9 4.1 3 1 1 4 4 3 1 Nuclear RNA-splicing-associated protein SelP_N PF04592.14 CDJ57663.1 - 0.0027 17.2 11.9 0.0027 17.2 11.9 3.1 3 0 0 3 3 3 1 Selenoprotein P, N terminal region Caps_synth_GfcC PF06251.11 CDJ57663.1 - 0.078 12.6 4.0 0.14 11.8 4.0 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC TCP PF03634.13 CDJ57663.1 - 0.12 12.9 32.8 0.35 11.4 8.9 3.1 3 0 0 3 3 3 0 TCP family transcription factor AAA_23 PF13476.6 CDJ57663.1 - 0.37 11.3 11.3 0.1 13.1 5.7 2.3 2 0 0 2 2 2 0 AAA domain SpoIIIAH PF12685.7 CDJ57663.1 - 0.92 9.3 24.4 1.5 8.6 1.8 3.1 3 0 0 3 3 3 0 SpoIIIAH-like protein U1snRNP70_N PF12220.8 CDJ57663.1 - 2 9.1 13.4 1.7 9.4 5.2 2.8 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rrp15p PF07890.12 CDJ57663.1 - 3.1 8.1 15.7 0.24 11.7 4.4 3.1 3 0 0 3 3 3 0 Rrp15p RNA_polI_A34 PF08208.11 CDJ57663.1 - 3.6 7.6 26.7 3 7.9 0.1 3.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 RPA43_OB PF17875.1 CDJ57663.1 - 4.7 7.8 13.4 6.7 7.4 3.3 3.3 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I EMC3_TMCO1 PF01956.16 CDJ57663.1 - 4.7 6.9 4.7 9 6.0 4.7 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF5094 PF17015.5 CDJ57663.1 - 6.3 6.9 19.3 1.3 9.1 5.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) Macoilin PF09726.9 CDJ57665.1 - 0.0065 15.1 20.6 0.0081 14.8 20.6 1.2 1 0 0 1 1 1 1 Macoilin family Ndc1_Nup PF09531.10 CDJ57665.1 - 0.055 12.2 11.2 0.07 11.8 11.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 CDJ57665.1 - 0.24 11.3 18.0 0.32 10.9 18.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Miga PF10265.9 CDJ57665.1 - 0.5 9.3 16.9 0.68 8.8 16.9 1.2 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 CDJ57665.1 - 0.56 10.1 30.7 0.79 9.6 30.7 1.1 1 0 0 1 1 1 0 SPX domain SAPS PF04499.15 CDJ57665.1 - 1.5 7.5 10.2 2 7.1 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 CDJ57665.1 - 1.9 7.5 9.1 2.8 6.9 9.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SLC12 PF03522.15 CDJ57665.1 - 3.7 6.5 10.6 4.8 6.1 10.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ57665.1 - 4.2 7.1 10.2 5.8 6.6 10.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 CDJ57665.1 - 5.3 4.7 18.9 7 4.3 18.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RskA PF10099.9 CDJ57669.1 - 0.17 12.2 0.0 0.17 12.2 0.0 8.9 4 3 3 8 8 8 0 Anti-sigma-K factor rskA NBD_C PF17042.5 CDJ57669.1 - 2.8 8.4 0.0 2.8 8.4 0.0 8.3 6 2 3 9 9 9 0 Nucleotide-binding C-terminal domain CAP_GLY PF01302.25 CDJ57671.1 - 1.3e-08 34.7 0.0 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 CAP-Gly domain DUF2722 PF10846.8 CDJ57671.1 - 0.00083 18.4 8.0 0.001 18.1 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ57671.1 - 0.0036 17.4 11.0 0.0047 17.0 11.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ57671.1 - 0.0056 15.9 11.6 0.0056 15.9 11.6 1.9 2 0 0 2 2 2 1 SprA-related family DDHD PF02862.17 CDJ57671.1 - 0.0076 16.4 0.7 0.0083 16.3 0.7 1.2 1 0 0 1 1 1 1 DDHD domain MecA PF05389.12 CDJ57671.1 - 0.0085 15.8 3.0 0.012 15.3 3.0 1.2 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) ORC_WH_C PF18137.1 CDJ57671.1 - 0.019 15.1 10.2 0.028 14.5 10.2 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SpoIIP PF07454.11 CDJ57671.1 - 0.098 12.1 5.8 0.13 11.7 5.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Myc_N PF01056.18 CDJ57671.1 - 0.13 12.1 4.6 0.2 11.5 4.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.12 CDJ57671.1 - 0.25 10.8 11.2 0.34 10.3 11.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Band_3_cyto PF07565.13 CDJ57671.1 - 0.25 11.1 4.4 0.33 10.7 4.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ57671.1 - 0.29 9.9 7.7 0.38 9.5 7.7 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ57671.1 - 0.33 10.7 7.9 0.46 10.3 7.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 CDJ57671.1 - 0.53 10.0 5.1 0.84 9.3 5.1 1.4 1 0 0 1 1 1 0 FAM176 family TERB2 PF15101.6 CDJ57671.1 - 0.58 10.2 10.8 0.85 9.6 10.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MAS20 PF02064.15 CDJ57671.1 - 0.6 10.2 12.2 1 9.5 12.2 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor eIF-3_zeta PF05091.12 CDJ57671.1 - 0.66 8.9 9.6 0.82 8.6 9.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 CDJ57671.1 - 0.73 10.5 27.4 1.9 9.2 0.7 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.16 CDJ57671.1 - 1.1 9.3 2.4 1.4 8.9 2.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CDJ57671.1 - 1.2 9.1 10.5 1.6 8.7 10.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIF_C PF14721.6 CDJ57671.1 - 1.2 9.5 6.0 2.1 8.7 6.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sox_N PF12444.8 CDJ57671.1 - 1.2 10.3 4.6 1.4 10.1 2.8 2.0 2 0 0 2 2 1 0 Sox developmental protein N terminal DUF4834 PF16118.5 CDJ57671.1 - 1.5 9.8 12.5 2.6 9.1 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ57671.1 - 1.6 8.3 29.6 2.4 7.7 29.6 1.1 1 0 0 1 1 1 0 Spt20 family ALMT PF11744.8 CDJ57671.1 - 1.7 7.4 3.3 2.1 7.1 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4175 PF13779.6 CDJ57671.1 - 1.7 6.5 20.6 2.5 5.9 20.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MDM31_MDM32 PF08118.11 CDJ57671.1 - 2.1 6.9 7.5 2.9 6.5 7.5 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins EIIBC-GUT_N PF03612.14 CDJ57671.1 - 2.2 8.0 6.4 3.4 7.4 6.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Roughex PF06020.11 CDJ57671.1 - 2.4 7.2 12.4 3.3 6.7 12.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3464 PF11947.8 CDJ57671.1 - 3.5 7.4 8.6 5.5 6.7 8.6 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 CDJ57671.1 - 4.5 7.0 6.1 6.1 6.5 6.1 1.1 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 CDJ57671.1 - 8 5.3 4.7 9.6 5.0 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.7 CDJ57671.1 - 8 4.5 7.4 9.6 4.2 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paf1 PF03985.13 CDJ57671.1 - 8.2 5.3 18.5 11 4.9 18.5 1.1 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 CDJ57671.1 - 8.7 4.1 9.6 11 3.8 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2b PF00587.25 CDJ57673.1 - 1.7e-33 116.1 0.1 5.3e-33 114.5 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDJ57673.1 - 3.1e-20 72.4 1.2 3.1e-20 72.4 1.2 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Spt20 PF12090.8 CDJ57673.1 - 7.2 6.1 8.7 14 5.2 8.7 1.4 1 0 0 1 1 1 0 Spt20 family TCTP PF00838.17 CDJ57674.1 - 1.3e-54 185.0 1.6 1.5e-54 184.8 1.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.17 CDJ57674.1 - 0.064 12.4 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) DUF2722 PF10846.8 CDJ57676.1 - 0.00016 20.8 6.4 0.00016 20.8 6.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) AP2 PF00847.20 CDJ57676.1 - 0.065 13.5 5.2 0.48 10.7 0.1 3.8 4 0 0 4 4 4 0 AP2 domain TFIIA PF03153.13 CDJ57676.1 - 0.37 10.7 36.5 0.039 14.0 15.5 3.0 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ57676.1 - 1.4 7.6 6.8 2.9 6.6 6.8 1.4 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 CDJ57676.1 - 2.9 7.6 5.3 5.7 6.6 5.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.12 CDJ57676.1 - 3.2 6.6 9.2 7.3 5.4 9.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Baculo_PP31 PF05311.11 CDJ57676.1 - 6.1 6.2 6.7 10 5.5 6.7 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PRC2_HTH_1 PF18118.1 CDJ57676.1 - 7.2 7.5 6.9 47 4.9 0.0 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain CDC27 PF09507.10 CDJ57677.1 - 0.022 14.2 17.8 0.028 13.8 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 CDJ57677.1 - 0.6 9.5 31.1 0.79 9.1 31.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CDJ57677.1 - 2.3 7.5 32.2 3 7.1 32.2 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 CDJ57677.1 - 3.8 5.8 27.3 5.8 5.2 27.3 1.3 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 CDJ57677.1 - 7.2 5.3 6.6 6.6 5.4 6.6 1.2 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 CDJ57678.1 - 2.9 6.6 11.3 6.1 5.5 11.3 1.5 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ57678.1 - 6.9 6.6 15.5 2.3 8.1 11.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DAGK_acc PF00609.19 CDJ57679.1 - 6.9e-20 72.0 0.0 1.2e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDJ57679.1 - 3.8e-17 62.1 0.0 4e-15 55.5 0.0 2.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 CDJ57680.1 - 3.7e-31 108.4 0.0 2.3e-29 102.6 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57680.1 - 8.6e-31 107.2 0.3 5.3e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase MORN PF02493.20 CDJ57680.1 - 2.7e-06 26.9 21.5 6.6e-05 22.6 0.4 4.2 4 0 0 4 4 4 2 MORN repeat SAM_1 PF00536.30 CDJ57680.1 - 0.0043 17.4 0.3 0.014 15.8 0.3 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) K_channel_TID PF07941.11 CDJ57680.1 - 0.016 15.6 1.8 0.016 15.6 1.8 10.4 12 2 1 13 13 13 0 Potassium channel Kv1.4 tandem inactivation domain DUF4149 PF13664.6 CDJ57682.1 - 1.4e-11 44.6 0.3 1.4e-11 44.6 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) PUL PF08324.11 CDJ57682.1 - 0.19 10.9 2.5 0.71 9.0 2.5 1.9 1 1 0 1 1 1 0 PUL domain AMP-binding PF00501.28 CDJ57684.1 - 8.6e-38 130.0 0.0 1.4e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ57684.1 - 7.3e-05 23.7 0.1 0.00013 22.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Creatinase_N PF01321.18 CDJ57684.1 - 0.031 14.9 0.1 0.049 14.3 0.1 1.3 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Pkinase PF00069.25 CDJ57685.1 - 1.7e-44 152.2 0.8 6.9e-31 107.6 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57685.1 - 1.7e-17 63.6 2.9 7.8e-12 45.0 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase WD40 PF00400.32 CDJ57687.1 - 6.1e-27 93.3 0.4 3.6e-08 33.9 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57687.1 - 1.5e-09 38.0 0.0 0.0049 17.1 0.1 3.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ57687.1 - 1.9e-08 33.7 1.7 0.052 12.5 0.0 3.6 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ57687.1 - 5.2e-06 25.4 0.1 0.014 14.0 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CDJ57687.1 - 0.001 19.0 0.1 0.18 11.6 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDJ57687.1 - 0.0059 16.0 0.0 0.07 12.4 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain PD40 PF07676.12 CDJ57687.1 - 0.0075 16.2 0.4 0.17 11.9 0.0 2.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 CDJ57687.1 - 0.013 14.4 0.0 0.097 11.6 0.1 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SPT16 PF08644.11 CDJ57688.1 - 3.9e-38 131.0 0.2 2e-32 112.5 0.2 3.1 4 0 0 4 4 4 2 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 CDJ57688.1 - 4.2e-16 59.1 0.4 1.7e-15 57.2 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like K_channel_TID PF07941.11 CDJ57688.1 - 0.016 15.6 10.4 0.031 14.7 10.4 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SPX PF03105.19 CDJ57689.1 - 8.2 6.2 17.1 2.9e+02 1.1 17.1 2.1 1 1 0 1 1 1 0 SPX domain AMA-1 PF02430.15 CDJ57690.1 - 1.1e-64 219.1 0.5 1.9e-62 211.8 0.5 2.1 1 1 0 1 1 1 1 Apical membrane antigen 1 Sec7 PF01369.20 CDJ57692.1 - 3.6e-45 153.9 0.0 5.3e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.18 CDJ57692.1 - 1.5e-32 113.0 0.9 6.9e-32 110.8 0.6 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Gal_Lectin PF02140.18 CDJ57693.1 - 1.1e-05 25.8 0.0 1.4e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Galactose binding lectin domain Sulfate_transp PF00916.20 CDJ57695.1 - 6.8e-74 248.9 14.5 1e-73 248.3 14.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDJ57695.1 - 5e-18 64.8 0.0 8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CDJ57695.1 - 0.0066 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 STAS domain UL41A PF17591.2 CDJ57695.1 - 1.2 9.3 3.1 6.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Herpesvirus UL41A TrbC PF04956.13 CDJ57696.1 - 0.15 12.3 8.9 0.065 13.5 5.8 2.0 2 0 0 2 2 2 0 TrbC/VIRB2 family Borrelia_REV PF03978.13 CDJ57696.1 - 0.16 11.9 8.5 0.024 14.6 1.8 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF572 PF04502.13 CDJ57696.1 - 1 8.9 44.1 2.1 7.9 17.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) HTH_50 PF18024.1 CDJ57698.1 - 0.12 12.0 2.3 0.32 10.7 0.4 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Rrn6 PF10214.9 CDJ57698.1 - 1.3 7.5 8.1 1.4 7.3 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2339 PF10101.9 CDJ57698.1 - 1.6 7.2 14.0 1.8 7.0 14.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4335 PF14233.6 CDJ57698.1 - 6 6.7 8.9 5.2 6.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) PHD_2 PF13831.6 CDJ57700.1 - 3.5e-10 39.2 0.7 6.8e-10 38.3 0.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 CDJ57700.1 - 1e-07 31.7 0.7 1e-07 31.7 0.7 1.6 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDJ57700.1 - 0.00021 21.1 0.2 0.00021 21.1 0.2 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 RskA PF10099.9 CDJ57701.1 - 0.0097 16.2 11.5 0.0097 16.2 11.5 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA HEAT PF02985.22 CDJ57701.1 - 0.02 15.1 1.9 0.041 14.1 0.2 2.6 2 0 0 2 2 2 0 HEAT repeat SUIM_assoc PF16619.5 CDJ57701.1 - 0.026 14.6 3.4 0.064 13.3 3.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CAP_N PF01213.19 CDJ57701.1 - 0.061 12.8 14.3 0.14 11.6 14.3 1.7 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spt20 PF12090.8 CDJ57701.1 - 0.087 12.4 7.8 0.068 12.8 6.5 1.5 2 0 0 2 2 2 0 Spt20 family SRA1 PF07304.11 CDJ57701.1 - 0.44 10.3 3.7 0.75 9.6 3.0 1.7 1 1 1 2 2 2 0 Steroid receptor RNA activator (SRA1) TFIIA PF03153.13 CDJ57701.1 - 2.1 8.2 14.3 2.8 7.8 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMP2_N PF18590.1 CDJ57702.1 - 1.1e-23 83.5 2.2 1.9e-23 82.8 2.2 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain GREB1 PF15782.5 CDJ57702.1 - 0.041 11.0 2.6 0.051 10.7 2.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SMYLE_N PF18615.1 CDJ57702.1 - 2.3 7.7 4.9 3.1 7.3 4.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain EF-hand_6 PF13405.6 CDJ57705.1 - 2.3e-06 27.1 0.1 9.9e-06 25.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CDJ57705.1 - 1.2e-05 25.7 0.1 0.0004 20.8 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ57705.1 - 1.2e-05 24.4 0.4 2.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDJ57705.1 - 0.04 13.8 0.0 10 6.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ57705.1 - 0.095 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 CDJ57705.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain ABC_tran PF00005.27 CDJ57706.1 - 7.3e-44 149.6 0.0 2.9e-26 92.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDJ57706.1 - 3.2e-36 125.2 32.8 2.4e-28 99.3 2.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDJ57706.1 - 1.4e-12 48.1 1.8 7.1e-08 32.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ57706.1 - 0.0069 16.1 2.2 0.09 12.5 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ57706.1 - 0.01 15.7 0.5 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF4162 PF13732.6 CDJ57706.1 - 0.024 15.3 0.0 6.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) SMC_N PF02463.19 CDJ57706.1 - 0.031 13.7 0.0 5.2 6.4 0.0 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ57706.1 - 0.035 14.6 3.9 0.039 14.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ57706.1 - 0.043 13.1 0.8 0.37 10.0 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 CDJ57706.1 - 0.6 10.2 3.2 0.4 10.8 0.5 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 CDJ57706.1 - 3.4 7.7 3.9 1.1 9.3 0.4 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Wzy_C PF04932.15 CDJ57707.1 - 0.019 14.6 0.1 0.019 14.6 0.1 2.0 2 0 0 2 2 2 0 O-Antigen ligase Spt20 PF12090.8 CDJ57708.1 - 0.011 15.3 10.2 0.022 14.4 10.2 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ57708.1 - 0.081 12.9 24.7 0.11 12.4 24.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIIC_sub6 PF10419.9 CDJ57708.1 - 0.33 10.9 2.5 0.56 10.1 2.4 1.5 1 1 0 1 1 1 0 TFIIIC subunit triple barrel domain DUF2722 PF10846.8 CDJ57708.1 - 0.74 8.7 12.3 0.044 12.7 7.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ57708.1 - 7.4 6.7 19.2 2.3 8.4 15.6 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 eIF3_subunit PF08597.10 CDJ57710.1 - 0.051 13.5 46.5 0.057 13.3 46.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Caldesmon PF02029.15 CDJ57710.1 - 0.088 11.6 45.7 0.093 11.5 45.7 1.1 1 0 0 1 1 1 0 Caldesmon DUF3807 PF12720.7 CDJ57710.1 - 0.21 11.9 34.1 0.23 11.7 34.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TFIIF_alpha PF05793.12 CDJ57710.1 - 0.68 8.5 44.5 0.99 7.9 44.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CDJ57710.1 - 1.2 7.3 37.8 1.2 7.3 37.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CDJ57710.1 - 1.2 8.5 43.7 1.6 8.1 43.7 1.3 1 0 0 1 1 1 0 SDA1 CCSAP PF15748.5 CDJ57710.1 - 1.8 8.7 35.2 2.8 8.0 35.2 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated NPR3 PF03666.13 CDJ57710.1 - 2.2 7.0 31.5 2.3 6.9 31.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ57710.1 - 2.6 7.8 40.5 3.9 7.2 40.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ57710.1 - 3.5 6.3 31.6 3.7 6.2 31.6 1.1 1 0 0 1 1 1 0 Presenilin FGF-BP1 PF06473.12 CDJ57710.1 - 5.3 6.8 30.1 8.3 6.2 30.1 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Zip PF02535.22 CDJ57710.1 - 5.3 6.2 21.5 6.2 5.9 21.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 CDJ57710.1 - 8.7 6.6 42.6 9.9 6.4 42.6 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SLC12 PF03522.15 CDJ57710.1 - 9.2 5.2 28.5 9.7 5.1 28.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ57710.1 - 9.5 6.4 19.5 12 6.1 19.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Rad51 PF08423.11 CDJ57712.1 - 4.8e-16 58.8 22.2 3.5e-09 36.3 4.1 3.9 4 1 0 5 5 5 2 Rad51 RecA PF00154.21 CDJ57712.1 - 1.8e-06 27.7 1.4 0.00013 21.5 0.1 2.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DUF2722 PF10846.8 CDJ57712.1 - 0.0058 15.6 10.2 0.0058 15.6 10.2 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) NPR3 PF03666.13 CDJ57712.1 - 0.019 13.8 2.1 0.02 13.7 0.7 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 ATPase PF06745.13 CDJ57712.1 - 0.043 13.2 0.3 0.043 13.2 0.3 2.4 3 0 0 3 3 2 0 KaiC AAA_18 PF13238.6 CDJ57712.1 - 0.17 12.4 0.5 1.5 9.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain Spt20 PF12090.8 CDJ57712.1 - 0.19 11.3 42.7 0.27 10.8 3.7 3.2 3 0 0 3 3 3 0 Spt20 family Presenilin PF01080.17 CDJ57712.1 - 0.26 10.0 11.7 0.047 12.5 5.9 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 CDJ57712.1 - 0.54 10.3 4.6 0.88 9.6 2.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.15 CDJ57712.1 - 0.66 9.5 15.6 4 6.9 11.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist MRP-L28 PF09812.9 CDJ57712.1 - 1 9.5 29.1 0.16 12.1 20.3 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 CSG2 PF16965.5 CDJ57712.1 - 1.5 7.7 4.0 2.9 6.7 4.0 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator MutS_II PF05188.17 CDJ57712.1 - 1.6 9.0 9.0 0.068 13.5 1.1 2.5 2 0 0 2 2 2 0 MutS domain II NEMP PF10225.9 CDJ57712.1 - 2.5 7.7 6.3 1 9.0 3.4 1.8 2 0 0 2 2 2 0 NEMP family TFIIA PF03153.13 CDJ57712.1 - 2.7 7.9 58.9 0.87 9.5 13.8 2.9 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit EOS1 PF12326.8 CDJ57712.1 - 3 7.8 5.9 0.66 9.9 1.3 2.2 2 1 0 2 2 2 0 N-glycosylation protein XRCC4 PF06632.12 CDJ57712.1 - 3.4 6.4 13.9 0.69 8.7 8.4 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Coilin_N PF15862.5 CDJ57712.1 - 3.7 7.3 10.5 0.2 11.5 3.7 2.3 2 0 0 2 2 2 0 Coilin N-terminus DDHD PF02862.17 CDJ57712.1 - 3.8 7.6 12.1 0.085 13.0 2.1 2.6 2 1 0 2 2 2 0 DDHD domain PAXNEB PF05625.11 CDJ57712.1 - 6.7 5.7 9.5 0.44 9.6 0.1 2.3 2 0 0 2 2 2 0 PAXNEB protein AAA_22 PF13401.6 CDJ57712.1 - 9.8 6.5 7.9 0.52 10.6 0.2 2.8 3 2 0 3 3 2 0 AAA domain TPR_14 PF13428.6 CDJ57714.1 - 7.5e-07 29.5 9.2 0.52 11.3 0.0 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat HAT PF02184.16 CDJ57714.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat RRS1 PF04939.12 CDJ57715.1 - 6.6e-06 26.1 0.0 7.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) WD40 PF00400.32 CDJ57716.1 - 1.8e-18 66.5 0.3 2.9e-08 34.2 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57716.1 - 1.6e-09 37.9 0.0 0.00018 21.7 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ57716.1 - 2.1e-05 23.6 0.1 0.0014 17.7 0.0 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDJ57716.1 - 0.00062 18.4 0.0 0.00066 18.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 CDJ57716.1 - 0.037 12.7 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.11 CDJ57716.1 - 0.049 13.3 0.1 7.3 6.2 0.0 3.2 1 1 3 4 4 4 0 TUP1-like enhancer of split PhaG_MnhG_YufB PF03334.14 CDJ57716.1 - 0.07 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter subunit eIF2A PF08662.11 CDJ57716.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A K_channel_TID PF07941.11 CDJ57717.1 - 0.007 16.8 7.4 0.007 16.8 7.4 2.8 3 0 0 3 3 1 1 Potassium channel Kv1.4 tandem inactivation domain EURL PF06937.11 CDJ57717.1 - 0.023 14.1 10.3 0.027 13.9 10.3 1.0 1 0 0 1 1 1 0 EURL protein EF-1_beta_acid PF10587.9 CDJ57717.1 - 0.037 14.5 2.4 0.037 14.5 2.4 3.6 2 1 0 2 2 1 0 Eukaryotic elongation factor 1 beta central acidic region Draxin PF15550.6 CDJ57717.1 - 0.1 12.5 8.3 0.12 12.2 8.3 1.0 1 0 0 1 1 1 0 Draxin CDC45 PF02724.14 CDJ57717.1 - 0.11 10.8 9.4 0.11 10.8 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 CDJ57717.1 - 0.12 11.9 5.9 0.14 11.6 5.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Med15 PF09606.10 CDJ57717.1 - 0.21 10.2 19.8 0.31 9.7 19.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IHABP4_N PF16174.5 CDJ57717.1 - 0.27 11.8 18.9 0.34 11.5 18.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal MRC1 PF09444.10 CDJ57717.1 - 0.57 10.7 16.8 0.94 10.0 16.8 1.3 1 0 0 1 1 1 0 MRC1-like domain eIF-3_zeta PF05091.12 CDJ57717.1 - 0.69 8.8 10.7 0.66 8.9 10.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.18 CDJ57717.1 - 1.3 8.5 6.1 1.6 8.3 6.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Exonuc_VII_L PF02601.15 CDJ57717.1 - 1.6 8.2 15.8 1.9 8.0 15.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM176 PF14851.6 CDJ57717.1 - 1.6 8.3 8.0 2.2 7.9 8.0 1.3 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.13 CDJ57717.1 - 1.8 8.5 24.5 2.1 8.2 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ57717.1 - 2.2 8.2 8.4 2.6 8.0 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RskA PF10099.9 CDJ57717.1 - 2.2 8.5 17.7 5.2 7.3 17.7 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF1943 PF09172.11 CDJ57717.1 - 2.5 7.2 7.1 2.9 7.0 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Peptidase_C98 PF15499.6 CDJ57717.1 - 2.6 7.5 7.8 3.2 7.1 7.8 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TERB2 PF15101.6 CDJ57717.1 - 2.8 7.9 11.1 3.8 7.5 11.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EOS1 PF12326.8 CDJ57717.1 - 2.8 7.8 4.0 3.2 7.6 4.0 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF2828 PF11443.8 CDJ57717.1 - 3.6 5.6 14.0 4.3 5.3 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 CDJ57717.1 - 3.7 7.5 6.7 4.6 7.2 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ57717.1 - 5.4 5.7 6.5 5.7 5.7 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0242 PF06785.11 CDJ57717.1 - 6.5 6.8 20.8 7.5 6.6 20.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDHD PF02862.17 CDJ57717.1 - 6.6 6.8 9.4 7.5 6.6 9.4 1.1 1 0 0 1 1 1 0 DDHD domain RskA PF10099.9 CDJ57718.1 - 0.0082 16.5 1.8 0.0082 16.5 1.8 6.2 4 2 0 5 5 5 2 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ57718.1 - 0.013 15.2 5.8 0.013 15.2 5.8 7.1 3 2 3 6 6 6 0 Domain of unknown function (DUF4207) Rxt3 PF08642.10 CDJ57718.1 - 0.013 16.3 1.7 0.013 16.3 1.7 7.4 3 2 3 6 6 6 0 Histone deacetylation protein Rxt3 Med15 PF09606.10 CDJ57719.1 - 7.2 5.2 13.8 9.9 4.7 13.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAP1 PF08601.10 CDJ57721.1 - 0.0047 16.7 14.2 0.0047 16.7 14.2 2.8 3 0 0 3 3 3 1 Transcription factor PAP1 CDC45 PF02724.14 CDJ57721.1 - 2.7 6.2 32.3 1.1 7.5 3.2 2.4 2 0 0 2 2 2 0 CDC45-like protein Nop PF01798.18 CDJ57722.1 - 6e-59 199.3 0.1 1.5e-58 198.0 0.1 1.7 1 1 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CDJ57722.1 - 5.2e-18 66.1 4.9 1.4e-17 64.8 4.9 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain Ribosomal_60s PF00428.19 CDJ57722.1 - 0.065 13.8 21.9 0.58 10.8 9.6 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein TFIID_20kDa PF03847.13 CDJ57723.1 - 0.074 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Apt1 PF10351.9 CDJ57723.1 - 1.3 7.7 4.9 1.7 7.4 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ57723.1 - 1.4 7.4 5.8 2.3 6.7 5.8 1.3 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 CDJ57723.1 - 7.5 5.1 5.7 85 1.6 7.6 1.9 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) RskA PF10099.9 CDJ57724.1 - 0.36 11.1 0.0 0.033 14.5 14.6 4.9 2 2 3 5 5 5 0 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ57725.1 - 0.0013 18.4 7.5 0.0013 18.4 7.5 3.5 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein DUF4207 PF13904.6 CDJ57728.1 - 0.043 13.5 4.4 0.079 12.6 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Fis1_TPR_C PF14853.6 CDJ57730.1 - 6.1e-07 29.4 0.3 7.7e-07 29.1 0.3 1.1 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CDJ57730.1 - 0.00014 21.5 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ57730.1 - 0.00042 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ57730.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ57730.1 - 0.02 15.5 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ57730.1 - 0.084 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps39_2 PF10367.9 CDJ57730.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Nkap_C PF06047.11 CDJ57731.1 - 5.2e-24 84.3 0.4 5.2e-24 84.3 0.4 3.8 4 1 0 4 4 4 1 NF-kappa-B-activating protein C-terminal domain DUF4667 PF15700.5 CDJ57731.1 - 0.0044 17.2 7.1 0.0044 17.2 7.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) tRNA-synt_1b PF00579.25 CDJ57732.1 - 0.0074 15.6 0.1 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Ribosomal_60s PF00428.19 CDJ57732.1 - 0.0086 16.7 0.4 0.0086 16.7 0.4 4.2 3 1 1 4 4 4 1 60s Acidic ribosomal protein CAP_N PF01213.19 CDJ57732.1 - 3.1 7.2 7.0 3.4 7.0 0.0 2.6 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_L37ae PF01780.19 CDJ57733.1 - 7.8e-41 138.1 8.1 8.9e-41 137.9 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 CDJ57733.1 - 0.002 18.1 1.6 0.0029 17.5 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDJ57733.1 - 0.0076 16.1 1.1 0.014 15.3 1.1 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Elf1 PF05129.13 CDJ57733.1 - 0.018 15.1 1.1 0.033 14.2 1.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 CDJ57733.1 - 0.041 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 CDJ57733.1 - 0.082 12.6 2.1 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 CDJ57733.1 - 0.24 11.7 0.8 0.24 11.7 0.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDJ57733.1 - 1.7 9.2 5.8 0.88 10.1 1.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain GILT PF03227.16 CDJ57735.1 - 3.1e-22 78.8 0.5 1.2e-21 77.0 0.1 2.0 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) LSM PF01423.22 CDJ57736.1 - 8.9e-16 57.3 1.3 1.1e-15 57.0 1.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDJ57736.1 - 0.034 14.3 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 CDJ57736.1 - 0.042 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Hfq protein RCC1 PF00415.18 CDJ57737.1 - 3.6e-15 56.3 11.6 4.1e-10 40.1 0.1 4.8 4 1 0 4 4 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ57737.1 - 2.2e-08 33.7 0.9 9.4e-07 28.5 0.2 2.5 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 CDJ57737.1 - 0.0098 15.9 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 1 Kelch motif RskA PF10099.9 CDJ57737.1 - 0.017 15.4 14.6 0.017 15.4 14.6 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA FdhD-NarQ PF02634.15 CDJ57737.1 - 0.047 13.4 7.4 0.071 12.8 7.4 1.2 1 0 0 1 1 1 0 FdhD/NarQ family GPCR_chapero_1 PF11904.8 CDJ57737.1 - 0.049 13.1 3.5 0.065 12.7 3.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF1980 PF09323.10 CDJ57737.1 - 1.7 8.5 4.7 3.2 7.6 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDJ57737.1 - 1.8 8.5 5.9 2.2 8.3 5.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RIFIN PF02009.16 CDJ57737.1 - 2.6 7.9 8.7 3.7 7.3 8.7 1.2 1 0 0 1 1 1 0 Rifin Presenilin PF01080.17 CDJ57737.1 - 2.7 6.6 11.6 3.5 6.3 11.6 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 CDJ57737.1 - 3.6 7.1 17.0 6 6.3 17.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gar1 PF04410.14 CDJ57738.1 - 7.3e-24 84.3 2.5 1.7e-23 83.1 2.5 1.6 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region RPN13_C PF16550.5 CDJ57739.1 - 3.7e-06 27.1 0.7 6.5e-06 26.3 0.7 1.4 1 1 0 1 1 1 1 UCH-binding domain Presenilin PF01080.17 CDJ57740.1 - 4.4 6.0 74.3 0.023 13.5 19.3 2.3 2 0 0 2 2 2 0 Presenilin Caldesmon PF02029.15 CDJ57741.1 - 0.0019 17.0 41.2 0.0019 17.0 41.2 1.6 2 0 0 2 2 2 1 Caldesmon Nop14 PF04147.12 CDJ57741.1 - 8 4.5 52.0 0.064 11.5 43.5 1.7 2 0 0 2 2 2 0 Nop14-like family RAP1 PF07218.11 CDJ57742.1 - 8.3 4.6 5.0 11 4.1 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ThiF PF00899.21 CDJ57743.1 - 1.8e-10 40.6 0.5 9.3e-08 31.7 0.4 2.2 2 0 0 2 2 2 1 ThiF family DUF5308 PF17233.2 CDJ57743.1 - 2.6e-05 24.5 3.3 0.058 13.6 2.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5308) DUF702 PF05142.12 CDJ57743.1 - 0.00077 20.0 8.2 0.013 15.9 1.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF702) TT_ORF2 PF02957.15 CDJ57743.1 - 0.0019 19.1 16.1 0.021 15.8 1.6 2.4 2 0 0 2 2 2 1 TT viral ORF2 DUF4471 PF14740.6 CDJ57743.1 - 0.0023 17.2 12.9 0.048 12.9 0.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) DUF775 PF05603.12 CDJ57743.1 - 0.003 17.1 9.5 0.048 13.2 2.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF775) SpoIIP PF07454.11 CDJ57743.1 - 0.0045 16.5 1.3 0.0045 16.5 1.3 2.1 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) SUIM_assoc PF16619.5 CDJ57743.1 - 0.0046 17.0 0.8 0.0046 17.0 0.8 3.8 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 OATP PF03137.20 CDJ57743.1 - 0.0047 15.3 3.7 0.36 9.1 0.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.8 CDJ57743.1 - 0.0076 15.3 38.3 0.039 12.9 22.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) FYDLN_acid PF09538.10 CDJ57743.1 - 0.013 16.1 25.7 0.017 15.8 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PTPRCAP PF15713.5 CDJ57743.1 - 0.015 15.6 5.3 0.015 15.6 5.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CNDH2_M PF16869.5 CDJ57743.1 - 0.016 15.9 14.1 0.81 10.4 0.2 2.2 2 0 0 2 2 2 0 PF16858 eIF3_subunit PF08597.10 CDJ57743.1 - 0.022 14.7 5.2 0.022 14.7 5.2 2.6 2 1 0 2 2 1 0 Translation initiation factor eIF3 subunit RPOL_N PF14700.6 CDJ57743.1 - 0.022 14.2 22.0 0.3 10.4 0.4 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF1840 PF08895.11 CDJ57743.1 - 0.026 14.9 0.7 0.026 14.9 0.7 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF1840) DUF4228 PF14009.6 CDJ57743.1 - 0.029 14.7 4.8 1.3 9.4 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CLN3 PF02487.17 CDJ57743.1 - 0.041 12.9 12.0 0.41 9.6 0.3 2.1 2 0 0 2 2 2 0 CLN3 protein Spt20 PF12090.8 CDJ57743.1 - 0.054 13.1 55.0 0.33 10.5 12.3 2.2 2 0 0 2 2 2 0 Spt20 family CPSF100_C PF13299.6 CDJ57743.1 - 0.055 13.6 0.6 0.055 13.6 0.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 CDJ57743.1 - 0.059 13.7 26.9 0.78 10.1 2.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Otopetrin PF03189.13 CDJ57743.1 - 0.063 12.1 6.4 0.093 11.5 6.4 1.2 1 0 0 1 1 1 0 Otopetrin Ctr PF04145.15 CDJ57743.1 - 0.074 13.7 3.8 2.6 8.6 2.2 2.2 2 0 0 2 2 2 0 Ctr copper transporter family FAM91_C PF14648.6 CDJ57743.1 - 0.081 11.8 7.8 0.92 8.3 0.2 2.1 2 0 0 2 2 2 0 FAM91 C-terminus TRAP_alpha PF03896.16 CDJ57743.1 - 0.094 11.9 16.2 0.33 10.1 3.8 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RP-C_C PF11800.8 CDJ57743.1 - 0.11 12.6 14.4 0.71 9.9 1.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CNDH2_C PF16858.5 CDJ57743.1 - 0.12 12.2 30.7 0.13 12.1 4.6 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF417 PF04224.12 CDJ57743.1 - 0.13 11.8 0.3 0.13 11.8 0.3 1.8 2 0 0 2 2 1 0 Protein of unknown function, DUF417 V_ATPase_I PF01496.19 CDJ57743.1 - 0.13 10.2 24.2 0.14 10.1 3.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ureide_permease PF07168.11 CDJ57743.1 - 0.17 10.6 14.1 0.8 8.4 0.3 2.1 2 0 0 2 2 2 0 Ureide permease PPL5 PF18168.1 CDJ57743.1 - 0.17 11.1 20.2 0.12 11.7 6.3 2.1 2 0 0 2 2 2 0 Prim-pol family 5 TT_ORF1 PF02956.14 CDJ57743.1 - 0.18 10.5 12.6 0.26 9.9 6.3 2.0 2 0 0 2 2 2 0 TT viral orf 1 YABBY PF04690.13 CDJ57743.1 - 0.23 12.0 11.2 4.5 7.8 0.0 2.2 2 0 0 2 2 2 0 YABBY protein Neur_chan_memb PF02932.16 CDJ57743.1 - 0.23 11.5 12.3 1.4 9.0 6.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1764 PF08576.10 CDJ57743.1 - 0.24 12.3 29.3 0.11 13.4 3.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3807 PF12720.7 CDJ57743.1 - 0.32 11.2 38.1 1.5 9.0 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PepSY_TM PF03929.16 CDJ57743.1 - 0.33 10.6 2.0 7.7 6.1 2.1 2.0 2 0 0 2 2 2 0 PepSY-associated TM region Rrp15p PF07890.12 CDJ57743.1 - 0.39 11.1 27.3 0.19 12.1 4.9 2.2 2 0 0 2 2 2 0 Rrp15p AAA_11 PF13086.6 CDJ57743.1 - 0.49 10.1 24.0 0.44 10.3 11.8 2.1 2 0 0 2 2 2 0 AAA domain BUD22 PF09073.10 CDJ57743.1 - 0.5 9.7 33.0 0.35 10.2 8.7 2.0 2 0 0 2 2 2 0 BUD22 MPM1 PF17234.2 CDJ57743.1 - 0.56 10.4 31.7 0.57 10.4 5.6 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4518 PF15008.6 CDJ57743.1 - 0.59 9.3 15.6 0.48 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) DUF3408 PF11888.8 CDJ57743.1 - 0.67 10.1 27.2 0.33 11.1 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) FAM60A PF15396.6 CDJ57743.1 - 0.83 9.6 20.9 2.3 8.2 12.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A MMR1 PF08505.10 CDJ57743.1 - 0.95 9.7 30.3 1.8 8.8 15.8 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PDCD2_C PF04194.13 CDJ57743.1 - 0.97 9.5 25.2 2.7 8.0 6.6 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain PEX11 PF05648.14 CDJ57743.1 - 1.2 8.6 10.6 0.74 9.2 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2052 PF09747.9 CDJ57743.1 - 1.3 9.1 40.6 0.073 13.2 10.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TCP PF03634.13 CDJ57743.1 - 1.4 9.5 23.5 0.51 10.9 0.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor EMC3_TMCO1 PF01956.16 CDJ57743.1 - 1.6 8.4 16.4 2.9 7.6 6.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like FAM76 PF16046.5 CDJ57743.1 - 1.6 8.0 26.3 2 7.7 14.4 2.1 2 0 0 2 2 2 0 FAM76 protein DUF3535 PF12054.8 CDJ57743.1 - 1.8 7.7 12.5 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) DUF4770 PF15994.5 CDJ57743.1 - 2 8.6 24.6 1.7 8.8 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RNA_pol_Rpc4 PF05132.14 CDJ57743.1 - 2 8.8 23.0 0.13 12.7 2.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 eIF-3_zeta PF05091.12 CDJ57743.1 - 2.4 7.0 29.1 3 6.7 17.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_U57 PF05582.12 CDJ57743.1 - 2.5 7.3 15.7 2.9 7.1 0.2 2.1 2 0 0 2 2 2 0 YabG peptidase U57 SNF5 PF04855.12 CDJ57743.1 - 2.6 7.8 24.2 1.4 8.7 16.4 2.1 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 Exonuc_VII_L PF02601.15 CDJ57743.1 - 2.6 7.5 16.4 1.5 8.3 10.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Suf PF05843.14 CDJ57743.1 - 2.7 7.9 17.9 3.5 7.5 9.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SLC12 PF03522.15 CDJ57743.1 - 3.1 6.7 26.9 2.1 7.2 2.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Myc_N PF01056.18 CDJ57743.1 - 3.5 7.4 26.2 1.8 8.4 7.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Cytomega_UL84 PF06284.11 CDJ57743.1 - 4.2 5.7 14.4 0.085 11.3 2.9 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein Membralin PF09746.9 CDJ57743.1 - 4.9 6.1 14.7 13 4.7 9.8 2.1 2 0 0 2 2 2 0 Tumour-associated protein GEMIN8 PF15348.6 CDJ57743.1 - 4.9 7.4 35.2 7 6.9 11.2 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 DUF4638 PF15472.6 CDJ57743.1 - 5.4 6.7 23.3 0.38 10.4 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) CSG2 PF16965.5 CDJ57743.1 - 5.7 5.8 12.7 3.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator CSRNP_N PF16019.5 CDJ57743.1 - 6.2 6.7 27.5 2.6 7.9 3.8 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4820 PF16091.5 CDJ57743.1 - 7.9 5.8 31.2 2.2 7.6 9.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ57743.1 - 8.1 7.5 38.0 8.8 7.4 19.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HNOBA PF07701.14 CDJ57743.1 - 8.2 5.8 17.2 2.1 7.8 1.1 2.3 2 0 0 2 2 2 0 Heme NO binding associated Gti1_Pac2 PF09729.9 CDJ57743.1 - 8.7 6.4 22.5 3.9 7.5 1.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3402 PF11882.8 CDJ57743.1 - 9.5 5.2 20.9 3.9 6.5 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) AP3D1 PF06375.11 CDJ57743.1 - 9.6 6.4 34.9 0.091 13.0 5.4 2.5 2 1 0 2 2 2 0 AP-3 complex subunit delta-1 DHQ_synthase PF01761.20 CDJ57744.1 - 2.8e-61 207.0 0.0 2.8e-61 207.0 0.0 2.8 3 0 0 3 3 3 1 3-dehydroquinate synthase EPSP_synthase PF00275.20 CDJ57744.1 - 5e-09 35.4 10.4 0.018 13.8 0.2 5.9 6 0 0 6 6 6 5 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SR-25 PF10500.9 CDJ57744.1 - 2.8e-05 23.9 18.5 2.8e-05 23.9 18.5 7.5 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein EPL1 PF10513.9 CDJ57744.1 - 0.0057 17.0 1.5 0.0057 17.0 1.5 6.9 5 2 0 6 6 6 1 Enhancer of polycomb-like PPP4R2 PF09184.11 CDJ57744.1 - 0.088 12.4 0.0 0.088 12.4 0.0 6.2 7 1 0 7 7 7 0 PPP4R2 RskA PF10099.9 CDJ57744.1 - 0.097 13.0 0.0 0.097 13.0 0.0 7.6 4 2 1 6 6 6 0 Anti-sigma-K factor rskA BUD22 PF09073.10 CDJ57744.1 - 2.4 7.4 85.0 0.021 14.2 6.2 5.5 4 1 0 4 4 4 0 BUD22 SID-1_RNA_chan PF13965.6 CDJ57744.1 - 4.5 5.6 28.3 0.032 12.6 0.2 4.2 4 1 1 5 5 5 0 dsRNA-gated channel SID-1 Shikimate_dh_N PF08501.11 CDJ57745.1 - 1.8e-09 37.7 0.0 5.2e-07 29.8 0.0 3.7 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain RskA PF10099.9 CDJ57745.1 - 8.5e-06 26.2 0.6 0.0059 16.9 11.3 13.4 5 3 2 7 7 7 3 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ57745.1 - 3.8e-05 23.4 10.2 3.8e-05 23.4 10.2 9.0 6 1 1 7 7 7 1 Spt20 family DUF4667 PF15700.5 CDJ57745.1 - 0.00032 20.9 9.4 0.00032 20.9 9.4 8.2 3 1 1 4 4 4 2 Domain of unknown function (DUF4667) SKI PF01202.22 CDJ57745.1 - 0.037 14.2 0.2 0.037 14.2 0.2 3.9 5 0 0 5 5 5 0 Shikimate kinase RNase_H2_suC PF08615.11 CDJ57745.1 - 0.1 12.8 0.0 0.1 12.8 0.0 5.0 3 1 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AP2 PF00847.20 CDJ57746.1 - 0.019 15.2 0.2 0.019 15.2 0.2 4.1 3 1 0 3 3 3 0 AP2 domain E1-E2_ATPase PF00122.20 CDJ57747.1 - 3.3e-42 144.0 0.0 3.3e-41 140.8 0.0 2.4 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CDJ57747.1 - 8.9e-18 63.8 0.0 2.1e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CDJ57747.1 - 4.8e-17 63.0 3.9 3.3e-15 56.9 3.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 CDJ57747.1 - 1.8e-16 60.4 1.1 4.3e-15 55.9 0.0 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDJ57747.1 - 6.2e-11 42.2 0.1 3.1e-10 40.0 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ57747.1 - 0.0031 17.3 1.4 0.0041 16.9 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1685 PF07939.11 CDJ57747.1 - 0.055 13.2 0.6 0.13 12.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) HAD PF12710.7 CDJ57747.1 - 0.089 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SMC_ScpB PF04079.16 CDJ57747.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB SpoIIM PF01944.17 CDJ57747.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.7 4 0 0 4 4 4 0 Stage II sporulation protein M Spc7 PF08317.11 CDJ57748.1 - 0.0035 16.3 11.2 0.0067 15.4 11.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein MAD PF05557.13 CDJ57748.1 - 0.044 12.2 14.2 0.064 11.6 14.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 CDJ57748.1 - 0.17 12.1 16.7 0.19 11.9 8.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CDJ57748.1 - 0.82 9.0 19.4 0.53 9.6 10.6 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 CDJ57748.1 - 1.1 9.8 9.8 0.23 12.0 2.5 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 CDJ57748.1 - 1.3 9.1 9.7 0.12 12.3 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1359 PF07097.11 CDJ57748.1 - 1.7 9.0 3.7 38 4.6 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) MAP7 PF05672.11 CDJ57748.1 - 2.2 8.0 13.5 3.5 7.3 13.5 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF2203 PF09969.9 CDJ57748.1 - 2.8 8.7 8.5 2.5 8.9 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Helo_like_N PF17111.5 CDJ57748.1 - 4.9 6.5 10.2 2 7.7 5.2 2.3 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Exonuc_VII_L PF02601.15 CDJ57748.1 - 6.2 6.3 9.8 9.1 5.7 9.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ57748.1 - 9 5.5 8.0 13 5.0 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec23_trunk PF04811.15 CDJ57749.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PP2C PF00481.21 CDJ57750.1 - 2.3e-33 115.9 0.0 5e-33 114.8 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ57750.1 - 0.0054 16.7 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) RskA PF10099.9 CDJ57751.1 - 0.00024 21.4 0.4 0.00024 21.4 0.4 16.3 7 6 7 14 14 14 2 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ57751.1 - 0.00037 18.8 4.2 0.00037 18.8 4.2 9.4 8 2 1 9 9 9 1 Sporozoite P67 surface antigen DUF4805 PF16063.5 CDJ57752.1 - 0.024 14.0 3.1 0.026 13.9 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Spt20 PF12090.8 CDJ57752.1 - 0.14 11.8 14.4 0.15 11.7 14.4 1.0 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ57752.1 - 0.27 10.1 9.6 0.29 10.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Shadoo PF14999.6 CDJ57752.1 - 0.37 10.9 11.6 0.4 10.8 11.6 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TonB_N PF16031.5 CDJ57752.1 - 0.43 11.1 4.9 0.47 11.0 4.9 1.1 1 0 0 1 1 1 0 TonB polyproline region BAT2_N PF07001.11 CDJ57752.1 - 1 9.8 10.0 1.1 9.7 10.0 1.0 1 0 0 1 1 1 0 BAT2 N-terminus Herpes_UL74 PF07982.12 CDJ57752.1 - 1 8.3 5.7 1 8.2 5.7 1.0 1 0 0 1 1 1 0 Herpes UL74 glycoproteins TFIIA PF03153.13 CDJ57752.1 - 2 8.3 12.7 2.3 8.1 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIFIN PF02009.16 CDJ57752.1 - 3.5 7.4 6.9 3.5 7.4 6.9 1.0 1 0 0 1 1 1 0 Rifin Roughex PF06020.11 CDJ57752.1 - 7.8 5.5 10.7 8 5.4 10.7 1.0 1 0 0 1 1 1 0 Drosophila roughex protein DLIC PF05783.11 CDJ57752.1 - 8 5.2 6.4 9.3 5.0 6.4 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF1645 PF07816.11 CDJ57753.1 - 0.006 17.2 13.6 0.0066 17.0 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) SR-25 PF10500.9 CDJ57753.1 - 0.013 15.1 25.2 0.021 14.5 25.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 CDJ57753.1 - 0.027 14.2 12.6 0.032 13.9 12.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 CDJ57753.1 - 0.048 12.6 26.8 0.065 12.2 26.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1168 PF06658.12 CDJ57753.1 - 0.083 12.7 12.7 0.11 12.4 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1635 PF07795.11 CDJ57753.1 - 0.092 12.6 18.3 0.12 12.2 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) eIF-3_zeta PF05091.12 CDJ57753.1 - 0.11 11.5 11.1 0.11 11.5 11.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_Me_trans PF04252.13 CDJ57753.1 - 0.11 12.0 3.7 0.12 11.9 3.7 1.1 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase TFIIA PF03153.13 CDJ57753.1 - 0.11 12.4 31.1 0.13 12.2 31.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 CDJ57753.1 - 0.18 12.1 7.6 0.22 11.9 7.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4392 PF14336.6 CDJ57753.1 - 0.19 11.1 0.7 0.21 11.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Macoilin PF09726.9 CDJ57753.1 - 0.24 9.9 17.9 0.26 9.8 17.9 1.0 1 0 0 1 1 1 0 Macoilin family DUF2052 PF09747.9 CDJ57753.1 - 0.35 11.0 11.4 0.41 10.7 11.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Med24_N PF11277.8 CDJ57753.1 - 0.4 8.7 12.6 0.48 8.4 12.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal CCDC24 PF15669.5 CDJ57753.1 - 0.43 10.4 14.0 0.64 9.9 14.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family FHIPEP PF00771.20 CDJ57753.1 - 0.47 8.9 4.8 0.51 8.7 4.8 1.0 1 0 0 1 1 1 0 FHIPEP family Plasmodium_Vir PF05795.11 CDJ57753.1 - 0.55 9.6 9.6 0.59 9.5 9.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 CDJ57753.1 - 0.66 7.0 21.9 0.72 6.9 21.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ57753.1 - 0.67 9.5 20.5 0.76 9.3 20.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4175 PF13779.6 CDJ57753.1 - 0.94 7.3 21.3 0.96 7.3 21.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MAP65_ASE1 PF03999.12 CDJ57753.1 - 1.1 7.9 20.0 1.3 7.7 20.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) V_ATPase_I PF01496.19 CDJ57753.1 - 1.2 6.9 9.3 1.2 7.0 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miga PF10265.9 CDJ57753.1 - 1.4 7.8 17.0 1.6 7.7 17.0 1.0 1 0 0 1 1 1 0 Mitoguardin CLN3 PF02487.17 CDJ57753.1 - 1.5 7.8 8.7 1.7 7.6 8.7 1.1 1 0 0 1 1 1 0 CLN3 protein SLC12 PF03522.15 CDJ57753.1 - 1.5 7.7 15.8 1.8 7.5 15.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ57753.1 - 1.9 9.6 14.0 2.3 9.4 14.0 1.1 1 0 0 1 1 1 0 Cdc42 effector Apt1 PF10351.9 CDJ57753.1 - 2.1 7.1 17.4 2.5 6.9 17.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol3_a_NII PF11490.8 CDJ57753.1 - 2.3 8.2 18.0 3.7 7.5 18.0 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PepSY_TM PF03929.16 CDJ57753.1 - 2.3 7.8 4.4 2.4 7.8 4.4 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Ureide_permease PF07168.11 CDJ57753.1 - 2.8 6.6 4.4 2.7 6.6 4.4 1.2 1 0 0 1 1 1 0 Ureide permease Folate_carrier PF01770.18 CDJ57753.1 - 2.9 6.5 6.3 2.8 6.6 6.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier NST1 PF13945.6 CDJ57753.1 - 3.6 7.7 25.0 4.4 7.4 25.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4407 PF14362.6 CDJ57753.1 - 3.9 6.7 10.2 3.9 6.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 CDJ57753.1 - 4.4 7.0 14.3 5.1 6.8 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 CDJ57753.1 - 5.3 7.1 13.7 8 6.5 13.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Conotoxin PF02950.17 CDJ57753.1 - 6.1 7.9 13.6 6.6 7.8 12.7 1.5 1 1 1 2 2 2 0 Conotoxin Sec62 PF03839.16 CDJ57753.1 - 6.5 6.2 9.0 7.9 5.9 9.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DivIC PF04977.15 CDJ57753.1 - 7.2 6.5 18.3 9.5 6.1 18.3 1.2 1 0 0 1 1 1 0 Septum formation initiator Ipi1_N PF12333.8 CDJ57753.1 - 7.4 7.2 12.6 0.71 10.5 3.4 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Presenilin PF01080.17 CDJ57753.1 - 9.3 4.9 20.6 12 4.6 20.6 1.0 1 0 0 1 1 1 0 Presenilin PHD_2 PF13831.6 CDJ57754.1 - 2.8e-11 42.7 1.6 2.8e-11 42.7 1.6 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CDJ57754.1 - 9.8e-11 41.4 4.9 2.1e-10 40.3 4.9 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CDJ57754.1 - 4.5e-05 23.3 0.5 4.5e-05 23.3 0.5 1.9 2 1 1 3 3 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDJ57754.1 - 0.00063 20.0 0.4 0.00063 20.0 0.4 2.3 3 0 0 3 3 3 1 C1 domain SOG2 PF10428.9 CDJ57754.1 - 0.01 15.1 16.0 0.013 14.7 16.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Prok-RING_1 PF14446.6 CDJ57754.1 - 0.015 15.2 2.2 0.015 15.2 2.2 1.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 CDJ57754.1 - 0.027 14.1 0.8 0.027 14.1 0.8 2.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF2318 PF10080.9 CDJ57754.1 - 0.065 13.4 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) HscB_4_cys PF18256.1 CDJ57754.1 - 0.1 12.4 1.5 0.29 11.0 1.5 1.8 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif SPX PF03105.19 CDJ57754.1 - 0.26 11.2 8.9 0.35 10.7 8.9 1.2 1 0 0 1 1 1 0 SPX domain ADK_lid PF05191.14 CDJ57754.1 - 0.98 9.5 0.0 0.98 9.5 0.0 3.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid DUF4551 PF15087.6 CDJ57754.1 - 2 7.2 7.5 2.3 6.9 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.9 CDJ57754.1 - 2.3 7.0 12.6 3 6.6 12.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA PF00004.29 CDJ57755.1 - 0.00012 22.5 17.0 0.00083 19.8 0.0 4.9 5 1 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) BAF250_C PF12031.8 CDJ57755.1 - 0.0037 16.6 0.4 0.0037 16.6 0.4 3.1 3 1 0 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa Spt20 PF12090.8 CDJ57755.1 - 0.011 15.3 19.7 0.011 15.3 19.7 5.7 5 1 0 5 5 5 0 Spt20 family MAP7 PF05672.11 CDJ57755.1 - 1.9 8.1 50.3 2.6 7.7 20.8 3.6 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family DUF1668 PF07893.13 CDJ57756.1 - 0.0046 16.4 0.2 0.0046 16.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) DUF572 PF04502.13 CDJ57756.1 - 1.4 8.5 37.4 0.71 9.4 5.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF572) RskA PF10099.9 CDJ57757.1 - 0.012 15.9 3.0 0.012 15.9 3.0 3.4 1 1 1 3 3 3 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ57757.1 - 8.9 7.0 15.1 2 9.1 6.2 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein TPH PF13868.6 CDJ57758.1 - 0.026 13.1 17.1 0.047 12.2 17.1 1.4 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain PNMA PF14893.6 CDJ57758.1 - 0.16 11.4 6.3 0.28 10.5 6.3 1.4 1 0 0 1 1 1 0 PNMA Chorion_2 PF03964.15 CDJ57758.1 - 0.18 12.7 10.0 0.055 14.3 6.1 2.0 2 0 0 2 2 2 0 Chorion family 2 PI3K_1B_p101 PF10486.9 CDJ57758.1 - 0.23 9.2 17.9 0.27 9.0 17.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MPM1 PF17234.2 CDJ57758.1 - 0.29 11.4 14.3 0.58 10.4 14.3 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF1168 PF06658.12 CDJ57758.1 - 0.5 10.2 20.3 1.1 9.1 20.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) AF-4 PF05110.13 CDJ57758.1 - 0.51 8.4 30.9 0.73 7.9 30.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CDJ57758.1 - 1 6.4 10.8 1 6.4 10.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 CDJ57758.1 - 1.4 7.4 15.0 1.5 7.2 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF508 PF04370.12 CDJ57758.1 - 2.7 7.7 13.3 4.9 6.9 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1635 PF07795.11 CDJ57758.1 - 5.1 6.9 16.4 4.6 7.0 15.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) TAF4 PF05236.14 CDJ57758.1 - 5.4 6.7 20.1 12 5.6 19.9 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4718 PF15842.5 CDJ57758.1 - 9.7 5.9 17.0 9.8 5.9 15.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) CW_binding_2 PF04122.12 CDJ57759.1 - 0.069 13.8 3.1 0.1 13.3 3.1 1.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 SET PF00856.28 CDJ57759.1 - 0.079 13.3 0.2 0.086 13.2 0.2 1.1 1 0 0 1 1 1 0 SET domain DUF4366 PF14283.6 CDJ57759.1 - 0.1 12.6 2.4 0.97 9.5 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Peptidase_M24 PF00557.24 CDJ57760.1 - 5.5e-15 55.6 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDJ57760.1 - 1.1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF982 PF06169.12 CDJ57760.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF982) FBPase PF00316.20 CDJ57761.1 - 1.4e-32 112.7 0.0 2.1e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CDJ57761.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Inositol monophosphatase family SF-assemblin PF06705.11 CDJ57763.1 - 4.2e-36 124.6 19.5 5e-36 124.3 19.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF713 PF05218.14 CDJ57763.1 - 0.051 13.3 8.2 0.046 13.5 3.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF713) Baculo_PEP_C PF04513.12 CDJ57763.1 - 0.095 12.7 10.4 0.13 12.3 0.2 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab_bind PF16704.5 CDJ57763.1 - 0.26 11.3 2.8 1.2 9.2 0.6 2.9 1 1 2 3 3 3 0 Rab binding domain Sigma70_ner PF04546.13 CDJ57763.1 - 5.6 6.8 16.4 1.7 8.5 5.4 2.6 1 1 1 2 2 2 0 Sigma-70, non-essential region Cid2 PF09774.9 CDJ57763.1 - 9.3 6.6 11.8 2.1 8.7 0.0 3.0 2 1 1 3 3 3 0 Caffeine-induced death protein 2 Ribosomal_L17 PF01196.19 CDJ57764.1 - 3.9e-19 69.3 0.1 5e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Pox_MCEL PF03291.16 CDJ57764.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Peptidase_C50 PF03568.17 CDJ57765.1 - 2.2e-05 23.8 0.0 4.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 Peptidase_S8 PF00082.22 CDJ57766.1 - 2.9e-31 108.8 0.6 5.3e-31 108.0 0.6 1.3 1 0 0 1 1 1 1 Subtilase family cEGF PF12662.7 CDJ57766.1 - 1.9e-05 24.5 2.3 4.4e-05 23.3 2.3 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CDJ57766.1 - 4.9e-05 23.4 10.5 9.8e-05 22.5 10.5 1.5 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.7 CDJ57766.1 - 0.06 13.4 6.7 0.13 12.4 6.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 Cu-binding_MopE PF11617.8 CDJ57766.1 - 0.092 12.9 3.1 0.24 11.6 3.1 1.7 1 0 0 1 1 1 0 Putative metal-binding motif EGF_CA PF07645.15 CDJ57766.1 - 0.16 12.2 15.9 0.42 10.9 9.8 2.5 2 0 0 2 2 2 0 Calcium-binding EGF domain hEGF PF12661.7 CDJ57766.1 - 0.18 12.5 2.2 0.48 11.1 2.2 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 CDJ57766.1 - 0.18 12.1 4.6 0.41 11.0 4.6 1.6 1 0 0 1 1 1 0 EGF-like domain V-SNARE_C PF12352.8 CDJ57767.1 - 4.4e-13 49.3 0.2 4.4e-13 49.3 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ57767.1 - 0.0079 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Sec20 AA_permease_2 PF13520.6 CDJ57767.1 - 0.012 14.4 0.6 0.017 14.0 0.6 1.1 1 0 0 1 1 1 0 Amino acid permease RRM_1 PF00076.22 CDJ57768.1 - 7e-10 38.6 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ57768.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif HEAT PF02985.22 CDJ57768.1 - 0.0047 17.1 9.4 0.019 15.2 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat DnaJ_C PF01556.18 CDJ57769.1 - 3.9e-33 114.6 0.1 5.5e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDJ57769.1 - 2.6e-23 81.9 1.9 4.3e-23 81.2 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDJ57769.1 - 9.9e-13 48.3 16.6 9.9e-13 48.3 16.6 1.9 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CDJ57769.1 - 0.047 13.7 9.4 1.4 8.9 2.2 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CDJ57769.1 - 0.35 10.9 10.7 1.7 8.7 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tnp_zf-ribbon_2 PF13842.6 CDJ57769.1 - 0.47 11.3 11.1 1.1 10.1 0.1 3.0 2 1 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon YcbB PF08664.10 CDJ57770.1 - 0.015 15.3 0.6 0.023 14.8 0.6 1.2 1 0 0 1 1 1 0 YcbB domain Ureide_permease PF07168.11 CDJ57771.1 - 1.7 7.3 11.6 0.04 12.7 0.8 3.5 2 0 0 2 2 2 0 Ureide permease Mlh1_C PF16413.5 CDJ57772.1 - 7.3e-54 183.0 0.4 7.3e-54 183.0 0.4 3.4 3 1 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDJ57772.1 - 4.8e-13 48.8 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDJ57772.1 - 5e-09 36.1 0.0 3.6e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ57772.1 - 0.0091 16.5 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUIM_assoc PF16619.5 CDJ57772.1 - 0.034 14.2 0.1 0.034 14.2 0.1 9.7 7 1 2 9 9 9 0 Unstructured region C-term to UIM in Ataxin3 Proteasome PF00227.26 CDJ57773.1 - 9.8e-22 77.4 1.6 4.3e-11 42.6 0.1 3.7 3 1 0 4 4 4 2 Proteasome subunit DUF4034 PF13226.6 CDJ57773.1 - 0.029 13.7 0.2 0.029 13.7 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4034) RskA PF10099.9 CDJ57773.1 - 0.048 14.0 28.2 1.3 9.3 9.9 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ57773.1 - 1.8 7.1 14.5 0.97 8.0 1.5 2.1 2 0 0 2 2 2 0 Hamartin protein PE_PPE_C PF12484.8 CDJ57773.1 - 2.4 9.1 33.1 3.3 8.7 16.5 3.0 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal Guanylate_kin PF00625.21 CDJ57774.1 - 0.12 12.0 0.1 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Guanylate kinase SUIM_assoc PF16619.5 CDJ57775.1 - 0.00068 19.7 0.0 0.00068 19.7 0.0 3.4 1 1 1 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CDJ57775.1 - 0.0077 15.0 5.1 0.008 15.0 5.1 1.2 1 0 0 1 1 1 1 Presenilin Spt20 PF12090.8 CDJ57775.1 - 0.013 15.1 25.8 0.11 12.0 27.6 1.6 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 CDJ57775.1 - 0.052 12.5 8.1 0.056 12.4 8.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 CDJ57775.1 - 0.098 12.9 9.0 0.14 12.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ57775.1 - 0.16 11.7 2.5 0.19 11.4 2.5 1.2 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ57775.1 - 0.18 11.8 1.5 0.21 11.6 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 CDJ57775.1 - 0.25 10.2 1.2 0.3 10.0 1.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RICTOR_N PF14664.6 CDJ57775.1 - 0.32 10.0 3.6 0.44 9.5 3.6 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF4834 PF16118.5 CDJ57775.1 - 0.39 11.7 10.5 0.74 10.8 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 CDJ57775.1 - 0.69 9.3 9.3 0.87 9.0 9.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EIIBC-GUT_N PF03612.14 CDJ57775.1 - 2.1 8.0 7.7 4 7.1 7.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 CDJ57775.1 - 3.1 5.6 8.9 3.6 5.4 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 CDJ57775.1 - 5.8 5.9 5.5 8 5.4 5.5 1.1 1 0 0 1 1 1 0 CLN3 protein DUF1980 PF09323.10 CDJ57775.1 - 6.9 6.5 6.6 9.9 6.0 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2227 PF09988.9 CDJ57776.1 - 2.9 7.7 4.5 43 3.9 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized metal-binding protein (DUF2227) Coatomer_WDAD PF04053.14 CDJ57778.1 - 1.2e-63 215.7 2.2 2.5e-29 102.6 0.7 3.3 1 1 2 3 3 3 3 Coatomer WD associated region WD40 PF00400.32 CDJ57778.1 - 3.2e-12 46.7 13.5 0.00011 22.9 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ASD2 PF08687.11 CDJ57778.1 - 0.17 11.5 9.2 0.24 10.9 9.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 TFIIA PF03153.13 CDJ57778.1 - 0.76 9.7 24.2 1.2 9.1 24.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 CDJ57778.1 - 1.2 9.8 14.8 0.92 10.1 6.6 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein FliD_N PF02465.18 CDJ57778.1 - 3.2 8.5 8.5 0.23 12.2 1.6 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TAP42 PF04177.12 CDJ57779.1 - 5.8e-14 51.9 3.0 1.7e-12 47.1 0.0 2.2 1 1 1 2 2 2 1 TAP42-like family Apt1 PF10351.9 CDJ57779.1 - 0.03 13.2 3.8 0.032 13.1 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Unpaired PF15972.5 CDJ57779.1 - 0.051 13.1 0.2 0.072 12.6 0.2 1.2 1 0 0 1 1 1 0 Unpaired protein Macoilin PF09726.9 CDJ57779.1 - 0.074 11.6 7.9 0.093 11.3 7.9 1.1 1 0 0 1 1 1 0 Macoilin family PepSY_TM_like_2 PF16357.5 CDJ57779.1 - 0.21 11.6 0.0 2.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Putative PepSY_TM-like GET2 PF08690.10 CDJ57779.1 - 1.5 8.4 6.3 6.8 6.3 3.3 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 TMEM51 PF15345.6 CDJ57779.1 - 3.4 7.4 7.0 7.3 6.4 4.5 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2722 PF10846.8 CDJ57781.1 - 0.00066 18.7 7.5 0.00066 18.7 7.5 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF2722) RIC3 PF15361.6 CDJ57781.1 - 0.025 15.0 14.8 2.6 8.4 11.0 2.9 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Apt1 PF10351.9 CDJ57781.1 - 0.36 9.6 11.8 5.4 5.8 11.8 2.1 1 1 0 1 1 1 0 Golgi-body localisation protein domain MFS_Mycoplasma PF07672.13 CDJ57781.1 - 0.48 9.7 0.0 0.48 9.7 0.0 2.1 3 0 0 3 3 3 0 Mycoplasma MFS transporter Connexin PF00029.19 CDJ57781.1 - 4.1 7.1 6.8 0.85 9.3 3.0 1.8 3 0 0 3 3 3 0 Connexin DUF2072 PF09845.9 CDJ57781.1 - 4.1 7.7 11.1 0.072 13.3 3.4 2.0 3 0 0 3 3 3 0 Zn-ribbon containing protein Lin-8 PF03353.15 CDJ57781.1 - 9.3 5.7 23.2 0.068 12.7 9.5 2.4 2 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist ASH PF15780.5 CDJ57783.1 - 2.3e-25 88.6 3.9 0.00033 20.8 0.1 9.9 8 2 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ57783.1 - 8.3e-21 74.1 3.8 0.00011 22.3 0.1 8.9 9 0 0 9 9 9 6 Flagellar-associated PapD-like DUF1573 PF07610.11 CDJ57783.1 - 2.2e-09 37.2 0.1 2.4 8.2 0.0 9.2 8 3 0 8 8 8 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CDJ57783.1 - 0.0001 22.1 0.0 3.7 7.5 0.0 5.6 6 0 0 6 6 6 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CDJ57783.1 - 0.0025 18.1 0.7 1.1e+02 3.2 0.0 6.2 8 0 0 8 8 8 0 Transmembrane protein 131-like MYCBPAP PF14646.6 CDJ57783.1 - 0.0036 16.3 0.0 8 5.3 0.0 3.8 5 0 0 5 5 5 2 MYCBP-associated protein family FixG_C PF11614.8 CDJ57783.1 - 0.026 14.7 0.0 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 IG-like fold at C-terminal of FixG, putative oxidoreductase fn3_5 PF06280.12 CDJ57783.1 - 0.034 14.8 0.4 10 6.8 0.0 3.7 4 0 0 4 4 4 0 Fn3-like domain DP-EP PF08985.11 CDJ57783.1 - 0.074 13.2 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 DP-EP family ATP-synt_C PF00137.21 CDJ57784.1 - 6.6e-30 103.2 32.9 3.8e-16 59.2 10.6 2.4 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CDJ57784.1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 IMCp PF12314.8 CDJ57785.1 - 5.2e-24 84.4 21.9 5.2e-24 84.4 21.9 4.0 1 1 2 3 3 3 3 Inner membrane complex protein ParA PF10609.9 CDJ57786.1 - 3.8e-69 232.9 0.0 1.6e-47 162.1 0.0 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 CDJ57786.1 - 2.8e-16 59.5 0.0 6.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 CDJ57786.1 - 5.1e-12 46.0 0.0 7.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ57786.1 - 9.6e-07 28.9 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CDJ57786.1 - 1.8e-06 27.5 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CDJ57786.1 - 0.00085 18.6 0.5 0.21 10.7 0.1 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 CDJ57786.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein APS_kinase PF01583.20 CDJ57786.1 - 0.04 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 CDJ57786.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 CDJ57786.1 - 0.18 10.7 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HNF-1_N PF04814.13 CDJ57787.1 - 0.84 10.2 9.0 14 6.3 0.1 2.8 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PP_M1 PF03012.14 CDJ57787.1 - 1.4 8.4 7.8 3.2 7.2 7.8 1.5 1 0 0 1 1 1 0 Phosphoprotein Apt1 PF10351.9 CDJ57787.1 - 3.9 6.2 10.4 8.9 5.0 10.4 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain OTU PF02338.19 CDJ57788.1 - 4.4e-10 40.1 0.0 7.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RING_2 PF13639.6 CDJ57789.1 - 3.7e-05 24.0 13.7 3.7e-05 24.0 13.7 2.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ57789.1 - 0.00014 21.7 10.0 0.00014 21.7 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ57789.1 - 0.0003 20.6 14.2 0.0003 20.6 14.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ57789.1 - 0.0022 17.8 12.8 0.0022 17.8 12.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ57789.1 - 0.0037 17.3 5.2 0.013 15.6 5.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ57789.1 - 0.0041 17.1 13.5 0.013 15.6 13.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ57789.1 - 0.025 14.7 12.5 0.025 14.7 12.5 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 CDJ57789.1 - 0.034 14.8 0.2 0.034 14.8 0.2 3.4 3 1 1 4 4 3 0 TRAF-type zinc finger zf-TRAF_2 PF15965.5 CDJ57789.1 - 0.24 11.9 17.5 0.5 10.9 7.1 2.8 3 0 0 3 3 2 0 TRAF-like zinc-finger zf-RING_4 PF14570.6 CDJ57789.1 - 0.26 11.1 9.6 2.1 8.2 9.9 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CDJ57789.1 - 4.2 7.4 23.2 0.085 12.8 14.9 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ57789.1 - 5.6 7.3 18.0 1.1 9.6 13.1 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Sina PF03145.16 CDJ57789.1 - 7.8 6.4 15.0 0.59 10.0 0.4 3.0 3 0 0 3 3 3 0 Seven in absentia protein family Voltage_CLC PF00654.20 CDJ57790.1 - 1.2e-38 133.3 51.1 5.2e-22 78.6 16.9 4.4 3 2 0 4 4 4 3 Voltage gated chloride channel zf-CCCH PF00642.24 CDJ57792.1 - 8e-10 38.4 11.8 5.5e-07 29.3 1.2 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ57792.1 - 8.1e-07 28.9 16.1 0.00045 20.2 1.5 3.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ57792.1 - 0.0026 17.5 15.9 0.0043 16.8 1.6 3.8 3 2 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 CDJ57792.1 - 0.028 15.1 8.6 0.079 13.7 0.4 2.7 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 CDJ57792.1 - 0.56 10.5 8.7 2.8 8.2 4.1 2.4 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ57792.1 - 1 9.9 12.9 7.7 7.1 1.9 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Cir_N PF10197.9 CDJ57793.1 - 3.2e-12 46.4 13.1 3.2e-12 46.4 13.1 3.5 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2844 PF11005.8 CDJ57794.1 - 0.0086 16.1 2.9 0.0086 16.1 2.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2844) Rsm1 PF08600.10 CDJ57794.1 - 0.092 12.9 0.4 0.092 12.9 0.4 2.1 2 0 0 2 2 2 0 Rsm1-like CCSAP PF15748.5 CDJ57794.1 - 0.7 10.0 12.1 1.1 9.3 12.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FTCD_C PF04961.12 CDJ57794.1 - 0.86 9.3 5.3 6.7 6.4 2.2 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Hydin_ADK PF17213.3 CDJ57794.1 - 1.1 9.5 9.3 1.1 9.5 7.8 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3464 PF11947.8 CDJ57794.1 - 1.3 8.8 8.5 4 7.2 0.6 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 ALMT PF11744.8 CDJ57794.1 - 1.4 7.7 7.1 1.7 7.4 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MAT1 PF06391.13 CDJ57794.1 - 2.8 7.7 18.7 4.6 7.0 18.7 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Renin_r PF07850.14 CDJ57794.1 - 2.9 8.6 4.0 12 6.6 0.6 2.3 2 0 0 2 2 2 0 Renin receptor-like protein DUF2967 PF11179.8 CDJ57794.1 - 3.1 5.8 20.1 0.1 10.7 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) FtsK_alpha PF17854.1 CDJ57794.1 - 3.7 7.7 6.7 5.1 7.3 0.4 2.4 2 0 0 2 2 2 0 FtsK alpha domain Med19 PF10278.9 CDJ57794.1 - 3.8 7.4 7.7 4.2 7.3 0.7 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 FlaG PF03646.15 CDJ57794.1 - 4.6 7.5 20.4 4.6 7.5 8.3 2.3 2 0 0 2 2 2 0 FlaG protein eIF_4EBP PF05456.11 CDJ57794.1 - 5 7.1 9.7 6.1 6.8 1.2 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) AFT PF08731.11 CDJ57794.1 - 5 7.6 8.7 65 4.0 7.2 2.3 2 1 0 2 2 2 0 Transcription factor AFT DUF775 PF05603.12 CDJ57794.1 - 6 6.4 14.9 7.6 6.0 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) FAM150 PF15129.6 CDJ57794.1 - 7.1 6.8 11.2 10 6.3 2.6 2.3 2 0 0 2 2 2 0 FAM150 family CDH1_2_SANT_HL1 PF18375.1 CDJ57794.1 - 8.3 7.2 7.2 12 6.6 0.4 2.9 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Usp PF00582.26 CDJ57794.1 - 8.3 6.9 7.6 2.4 8.7 3.9 1.9 1 1 1 2 2 2 0 Universal stress protein family Conotoxin PF02950.17 CDJ57794.1 - 8.5 7.5 11.6 12 7.0 1.9 3.0 3 0 0 3 3 3 0 Conotoxin DUF4834 PF16118.5 CDJ57794.1 - 9.6 7.2 17.2 5.1 8.1 4.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) DNA_pol_phi PF04931.13 CDJ57796.1 - 0.00068 17.9 40.2 0.00075 17.7 40.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 CDJ57796.1 - 0.00074 17.9 34.8 0.00086 17.7 34.8 1.0 1 0 0 1 1 1 1 Nop14-like family Connexin PF00029.19 CDJ57796.1 - 0.0056 16.5 5.4 0.0063 16.3 5.4 1.3 1 0 0 1 1 1 1 Connexin CDC45 PF02724.14 CDJ57796.1 - 0.013 13.8 25.2 0.016 13.5 25.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CDJ57796.1 - 0.014 13.9 34.3 0.015 13.8 34.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DDHD PF02862.17 CDJ57796.1 - 0.025 14.8 3.3 0.028 14.6 3.3 1.1 1 0 0 1 1 1 0 DDHD domain RRN3 PF05327.11 CDJ57796.1 - 0.035 12.7 22.3 0.04 12.5 22.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LTV PF04180.14 CDJ57796.1 - 0.037 13.8 18.8 0.049 13.4 18.8 1.1 1 0 0 1 1 1 0 Low temperature viability protein SpoIIP PF07454.11 CDJ57796.1 - 0.069 12.6 14.1 0.075 12.5 14.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S64 PF08192.11 CDJ57796.1 - 0.1 11.1 7.5 0.12 10.8 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 V_ATPase_I PF01496.19 CDJ57796.1 - 0.12 10.2 14.9 0.15 10.0 14.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 CDJ57796.1 - 0.16 12.4 10.8 0.19 12.1 10.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4471 PF14740.6 CDJ57796.1 - 0.19 10.9 6.2 0.27 10.4 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) SDA1 PF05285.12 CDJ57796.1 - 0.21 11.0 39.4 0.26 10.7 39.4 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 CDJ57796.1 - 0.24 10.8 34.6 0.26 10.6 34.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 CDJ57796.1 - 0.32 10.8 20.9 0.37 10.6 20.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Slu7 PF11708.8 CDJ57796.1 - 0.35 10.6 21.4 0.41 10.4 21.4 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Sec62 PF03839.16 CDJ57796.1 - 0.41 10.1 7.4 0.42 10.1 7.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 CDJ57796.1 - 0.46 9.2 12.6 0.47 9.2 12.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CDJ57796.1 - 0.51 9.3 11.8 0.59 9.0 11.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 CDJ57796.1 - 0.67 10.4 19.7 0.98 9.9 19.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_polI_A34 PF08208.11 CDJ57796.1 - 0.68 10.0 23.3 0.77 9.8 23.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SpoIIIAH PF12685.7 CDJ57796.1 - 0.69 9.7 19.8 0.86 9.4 19.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2151 PF10221.9 CDJ57796.1 - 0.83 8.2 11.6 0.89 8.1 11.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator BUD22 PF09073.10 CDJ57796.1 - 1.1 8.5 37.0 1.4 8.2 37.0 1.0 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 CDJ57796.1 - 1.1 8.1 7.6 1.2 8.0 7.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FRQ PF09421.10 CDJ57796.1 - 1.2 7.0 13.4 1.3 7.0 13.4 1.0 1 0 0 1 1 1 0 Frequency clock protein DUF4045 PF13254.6 CDJ57796.1 - 1.3 8.6 11.5 1.6 8.3 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 CDJ57796.1 - 1.6 7.4 15.3 1.7 7.3 15.3 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 CDJ57796.1 - 1.9 7.8 41.3 2.5 7.4 41.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gti1_Pac2 PF09729.9 CDJ57796.1 - 2.4 8.2 6.8 3 7.9 6.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family AAA_11 PF13086.6 CDJ57796.1 - 3 7.6 9.8 3.6 7.3 9.8 1.1 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.8 CDJ57796.1 - 3.6 7.6 8.6 4 7.5 8.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Lin-8 PF03353.15 CDJ57796.1 - 4.4 6.8 20.5 5.5 6.5 20.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ57796.1 - 9.7 4.9 12.5 12 4.6 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LAP1C PF05609.12 CDJ57796.1 - 9.8 5.1 17.0 12 4.9 17.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 CDJ57796.1 - 9.9 4.8 15.6 10 4.8 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAS_3 PF08447.12 CDJ57797.1 - 0.0023 18.2 0.0 0.67 10.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold DUF4175 PF13779.6 CDJ57797.1 - 0.049 11.6 4.4 0.073 11.0 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ank_5 PF13857.6 CDJ57798.1 - 1.4e-07 31.6 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ57798.1 - 2.5e-07 31.1 0.0 0.001 19.6 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ57798.1 - 1.6e-05 25.4 0.0 5.2e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ57798.1 - 7.6e-05 23.0 0.0 0.0058 17.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CDJ57798.1 - 0.046 14.3 0.0 0.37 11.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Kelch_4 PF13418.6 CDJ57799.1 - 0.00087 19.3 0.8 0.0016 18.4 0.8 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ57799.1 - 0.022 14.8 0.3 0.022 14.8 0.3 2.2 3 0 0 3 3 3 0 Kelch motif Retinal PF15449.6 CDJ57800.1 - 4.3 5.0 22.4 5.6 4.6 22.4 1.2 1 0 0 1 1 1 0 Retinal protein DUF1664 PF07889.12 CDJ57801.1 - 0.0098 15.9 6.1 0.0098 15.9 6.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 CDJ57801.1 - 0.036 14.9 4.8 0.036 14.9 4.8 2.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Baculo_PEP_C PF04513.12 CDJ57801.1 - 0.15 12.1 6.8 0.16 12.1 5.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 CDJ57801.1 - 0.33 9.9 17.3 0.65 8.9 8.6 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF745 PF05335.13 CDJ57801.1 - 0.35 10.5 21.4 0.023 14.4 14.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 CDJ57801.1 - 0.43 9.4 25.1 0.17 10.8 18.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CDJ57801.1 - 1.6 6.5 10.1 2 6.2 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Leu_zip PF15294.6 CDJ57801.1 - 1.7 8.1 19.9 5.8 6.3 18.6 2.1 1 1 0 1 1 1 0 Leucine zipper DUF4407 PF14362.6 CDJ57801.1 - 1.8 7.9 16.7 2.3 7.5 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 CDJ57801.1 - 1.8 8.0 21.0 0.44 10.0 17.2 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 UCH PF00443.29 CDJ57802.1 - 2.1e-33 115.9 8.5 1.5e-31 109.9 2.6 4.4 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ57802.1 - 5.5e-10 39.3 11.5 2.4e-08 33.9 8.1 5.9 6 1 0 6 6 6 2 Ubiquitin carboxyl-terminal hydrolase SDA1 PF05285.12 CDJ57802.1 - 2.2 7.6 0.0 0.2 11.0 34.8 5.0 6 0 0 6 6 6 0 SDA1 Vps53_N PF04100.12 CDJ57803.1 - 2.8e-17 62.8 10.4 2.8e-17 62.8 10.4 5.4 3 2 2 5 5 5 1 Vps53-like, N-terminal RskA PF10099.9 CDJ57803.1 - 0.00063 20.1 0.2 0.00063 20.1 0.2 8.8 2 2 3 6 6 6 1 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ57804.1 - 1.7e-17 63.7 0.0 2.6e-12 46.7 0.0 4.3 4 2 2 6 6 6 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57804.1 - 3.8e-07 29.7 0.0 3.8e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RNA_pol_Rpc4 PF05132.14 CDJ57804.1 - 0.0041 17.6 1.3 0.0041 17.6 1.3 10.0 9 3 1 10 10 10 1 RNA polymerase III RPC4 DDHD PF02862.17 CDJ57804.1 - 0.018 15.2 0.5 0.018 15.2 0.5 8.5 4 1 1 5 5 5 0 DDHD domain ATP-synt_D PF01813.17 CDJ57805.1 - 5.9e-58 195.9 1.9 5.9e-58 195.9 1.9 1.3 2 0 0 2 2 2 1 ATP synthase subunit D Pet20 PF08692.10 CDJ57806.1 - 2 9.1 8.3 23 5.7 8.2 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 SR-25 PF10500.9 CDJ57808.1 - 0.00013 21.6 31.9 0.0032 17.1 24.6 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Sas10_Utp3 PF04000.15 CDJ57808.1 - 0.0059 17.2 0.1 0.0059 17.2 0.1 2.9 2 1 1 3 3 3 1 Sas10/Utp3/C1D family SLATT_1 PF18181.1 CDJ57808.1 - 0.065 13.2 1.8 0.11 12.4 1.8 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PI3K_1B_p101 PF10486.9 CDJ57808.1 - 3 5.5 9.3 0.49 8.1 4.8 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF5542 PF17696.1 CDJ57808.1 - 3.5 7.8 5.0 13 6.0 5.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5542) SWIB PF02201.18 CDJ57809.1 - 9.1e-16 57.5 0.3 9.1e-16 57.5 0.3 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain RskA PF10099.9 CDJ57809.1 - 0.0048 17.2 16.1 0.0048 17.2 16.1 10.2 4 3 5 9 9 9 4 Anti-sigma-K factor rskA PP2C PF00481.21 CDJ57810.1 - 6.1e-32 111.3 3.4 1.5e-24 87.0 0.2 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C TFIIA PF03153.13 CDJ57810.1 - 0.00031 20.9 18.1 0.00038 20.6 18.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ57810.1 - 0.0016 17.4 6.8 0.0018 17.2 6.8 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ57810.1 - 0.0026 17.4 15.2 0.0034 17.0 15.2 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ57810.1 - 0.005 16.5 16.6 0.0076 15.9 16.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 CDJ57810.1 - 0.0058 16.4 10.5 0.0074 16.1 10.5 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 Presenilin PF01080.17 CDJ57810.1 - 0.0061 15.4 10.1 0.0074 15.1 10.1 1.1 1 0 0 1 1 1 1 Presenilin PP2C_2 PF13672.6 CDJ57810.1 - 0.0061 16.2 0.2 1.9 8.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Mem_trans PF03547.18 CDJ57810.1 - 0.014 13.8 1.8 0.015 13.7 1.8 1.1 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 CDJ57810.1 - 0.026 11.7 11.9 0.029 11.5 11.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDJ57810.1 - 0.042 12.4 11.6 0.049 12.2 11.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3506 PF12014.8 CDJ57810.1 - 0.052 13.6 3.2 0.088 12.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Cwf_Cwc_15 PF04889.12 CDJ57810.1 - 0.063 13.0 14.7 0.089 12.5 14.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1645 PF07816.11 CDJ57810.1 - 0.078 13.6 10.3 0.11 13.0 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ57810.1 - 0.16 11.5 28.8 0.28 10.8 28.8 1.3 1 0 0 1 1 1 0 Spt20 family SLY PF12485.8 CDJ57810.1 - 0.21 12.3 17.6 0.33 11.6 17.6 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Menin PF05053.13 CDJ57810.1 - 0.39 9.0 6.7 0.48 8.7 6.7 1.1 1 0 0 1 1 1 0 Menin AF-4 PF05110.13 CDJ57810.1 - 0.53 8.3 23.1 0.75 7.8 23.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4175 PF13779.6 CDJ57810.1 - 0.55 8.1 19.7 0.63 7.9 19.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Vfa1 PF08432.10 CDJ57810.1 - 0.62 10.4 16.4 0.9 9.8 16.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IMUP PF15761.5 CDJ57810.1 - 0.65 10.7 13.4 1.2 9.9 13.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein RR_TM4-6 PF06459.12 CDJ57810.1 - 0.79 9.5 11.7 1 9.1 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ57810.1 - 0.81 7.9 10.8 0.98 7.6 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 CDJ57810.1 - 0.85 9.0 8.3 1.2 8.5 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3306 PF11748.8 CDJ57810.1 - 0.85 10.5 9.2 1.7 9.5 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) eIF-3_zeta PF05091.12 CDJ57810.1 - 0.87 8.5 12.1 1.1 8.1 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.6 CDJ57810.1 - 1.2 7.9 13.7 1.6 7.4 13.7 1.1 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 CDJ57810.1 - 1.3 6.7 11.4 1.7 6.4 11.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SpoIIP PF07454.11 CDJ57810.1 - 1.4 8.3 13.4 2.2 7.6 13.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 CDJ57810.1 - 1.6 8.1 11.9 2 7.7 11.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CCSAP PF15748.5 CDJ57810.1 - 1.6 8.9 16.3 2.7 8.1 16.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ALMT PF11744.8 CDJ57810.1 - 1.9 7.3 13.9 2.8 6.7 13.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF908 PF06012.12 CDJ57810.1 - 3 7.2 11.4 4 6.8 11.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF755 PF05501.11 CDJ57810.1 - 3.1 8.1 31.7 13 6.1 31.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF755) PepSY_TM PF03929.16 CDJ57810.1 - 3.4 7.3 4.3 4.7 6.8 4.3 1.2 1 0 0 1 1 1 0 PepSY-associated TM region PTPRCAP PF15713.5 CDJ57810.1 - 4.8 7.5 21.1 8 6.7 21.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4692 PF15763.5 CDJ57810.1 - 5.1 7.5 10.2 7.9 6.9 10.2 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MDFI PF15316.6 CDJ57810.1 - 6 6.9 10.9 8.7 6.4 10.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Peptidase_S64 PF08192.11 CDJ57810.1 - 6.4 5.1 17.1 8.4 4.7 17.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 CDJ57810.1 - 7.4 6.6 10.2 11 6.0 10.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ57810.1 - 8.1 5.4 6.7 11 5.0 6.7 1.2 1 0 0 1 1 1 0 CLN3 protein Ribosomal_60s PF00428.19 CDJ57811.1 - 0.021 15.4 10.2 0.021 15.4 10.2 12.3 6 2 6 12 12 12 0 60s Acidic ribosomal protein DUF2052 PF09747.9 CDJ57811.1 - 0.023 14.8 36.3 0.13 12.4 15.2 3.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) AAA_22 PF13401.6 CDJ57811.1 - 0.092 13.0 2.9 0.2 11.9 0.9 2.6 2 1 1 3 3 3 0 AAA domain DUF4160 PF13711.6 CDJ57811.1 - 0.26 11.7 0.6 0.88 9.9 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Presenilin PF01080.17 CDJ57811.1 - 3.9 6.1 52.6 1.1 8.0 10.0 3.3 3 0 0 3 3 3 0 Presenilin RskA PF10099.9 CDJ57812.1 - 0.00086 19.6 0.0 0.00086 19.6 0.0 9.9 4 3 2 7 7 7 4 Anti-sigma-K factor rskA Otopetrin PF03189.13 CDJ57813.1 - 5.4e-06 25.5 0.0 0.65 8.7 0.0 5.9 4 3 0 4 4 4 1 Otopetrin S1 PF00575.23 CDJ57813.1 - 0.0071 16.7 0.0 5.9 7.3 0.1 5.0 6 0 0 6 6 6 1 S1 RNA binding domain NIF PF03031.18 CDJ57814.1 - 0.0055 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CobT PF06213.12 CDJ57814.1 - 0.029 13.8 30.2 0.097 12.0 17.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF2370 PF10176.9 CDJ57814.1 - 0.55 9.8 15.1 0.063 12.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SpoIIP PF07454.11 CDJ57814.1 - 0.94 8.9 24.5 0.17 11.3 1.3 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) BORG_CEP PF14957.6 CDJ57814.1 - 1.4 10.1 19.5 0.43 11.8 1.0 2.1 2 0 0 2 2 2 0 Cdc42 effector SelP_N PF04592.14 CDJ57814.1 - 3.5 7.0 36.3 0.51 9.7 17.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CCDC53 PF10152.9 CDJ57814.1 - 3.5 8.0 29.8 2.5 8.5 4.7 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Band_3_cyto PF07565.13 CDJ57814.1 - 5.3 6.8 29.0 0.18 11.6 6.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 CDJ57814.1 - 9 6.0 27.6 6.6 6.5 12.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PTPS PF01242.19 CDJ57815.1 - 2.8e-18 66.1 0.0 5.7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase zf-RING_2 PF13639.6 CDJ57816.1 - 3e-10 40.2 7.1 3e-10 40.2 7.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDJ57816.1 - 8.3e-10 38.8 8.2 4.3e-09 36.5 8.2 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ57816.1 - 1.4e-07 31.2 6.2 3.5e-07 30.0 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDJ57816.1 - 3.5e-05 23.9 4.0 8.4e-05 22.7 4.0 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 CDJ57816.1 - 4.3e-05 23.3 7.5 4.3e-05 23.3 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ57816.1 - 7.7e-05 22.7 3.7 0.00022 21.2 3.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ57816.1 - 0.00028 20.8 3.7 0.00028 20.8 3.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger RskA PF10099.9 CDJ57816.1 - 0.0012 19.2 9.2 0.0012 19.2 9.2 5.7 3 1 3 6 6 3 1 Anti-sigma-K factor rskA zf-RING_11 PF17123.5 CDJ57816.1 - 0.0013 18.4 6.8 0.0026 17.5 6.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 CDJ57816.1 - 0.0014 18.9 0.4 0.0014 18.9 0.4 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-RING_5 PF14634.6 CDJ57816.1 - 0.0077 16.2 6.0 0.0077 16.2 6.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_12 PF11331.8 CDJ57816.1 - 0.021 14.6 0.2 0.079 12.8 0.0 2.1 2 0 0 2 2 1 0 Probable zinc-ribbon domain zf-HC5HC2H_2 PF13832.6 CDJ57816.1 - 0.39 10.9 6.0 0.39 10.9 1.8 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.7 CDJ57816.1 - 0.68 10.1 7.3 1.6 8.9 7.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 CDJ57816.1 - 0.76 9.7 11.1 0.057 13.3 4.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CDJ57816.1 - 1.2 9.2 12.1 0.82 9.8 0.8 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 CDJ57816.1 - 2.1 8.1 11.7 0.26 11.0 4.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDJ57816.1 - 2.6 8.0 7.1 26 4.8 7.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 CDJ57816.1 - 5.7 6.9 14.1 12 5.9 5.4 3.0 2 1 0 2 2 2 0 PHD-finger NKAP PF15692.5 CDJ57818.1 - 1.8 9.3 6.5 0.23 12.2 2.3 1.6 2 0 0 2 2 2 0 NF-kappa-B-activating protein RskA PF10099.9 CDJ57818.1 - 2.9 8.2 26.0 1.4e+03 -0.6 26.0 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Myb_DNA-binding PF00249.31 CDJ57819.1 - 3.6e-08 33.5 0.0 9.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ57819.1 - 0.00017 21.8 0.1 0.00033 20.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AP2 PF00847.20 CDJ57820.1 - 0.093 13.0 0.0 0.093 13.0 0.0 3.5 3 0 0 3 3 3 0 AP2 domain Peptidase_C97 PF05903.14 CDJ57821.1 - 4.6e-36 123.9 0.0 7.7e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 CDJ57821.1 - 1.1e-05 25.3 0.1 6.9e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 CDJ57821.1 - 1.6e-05 24.7 1.7 2e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain LRAT PF04970.13 CDJ57821.1 - 0.02 15.2 0.3 0.083 13.2 0.0 2.1 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Mannitol_dh_C PF08125.13 CDJ57821.1 - 0.023 14.2 0.9 0.051 13.0 0.9 1.7 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain APG12 PF04110.13 CDJ57822.1 - 6.8e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 AAA_23 PF13476.6 CDJ57822.1 - 0.033 14.7 5.5 0.047 14.2 5.5 1.2 1 0 0 1 1 1 0 AAA domain Spore_GerAC PF05504.11 CDJ57822.1 - 0.061 13.5 1.4 0.084 13.1 1.4 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal BAF1_ABF1 PF04684.13 CDJ57822.1 - 0.089 11.8 15.6 0.11 11.5 15.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SOG2 PF10428.9 CDJ57822.1 - 3.6 6.7 36.1 5 6.2 36.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LMBR1 PF04791.16 CDJ57822.1 - 3.9 6.3 11.2 4.8 6.0 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RNase_T PF00929.24 CDJ57824.1 - 0.052 14.1 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Exonuclease Spt20 PF12090.8 CDJ57826.1 - 0.085 12.5 2.6 0.093 12.3 2.6 1.1 1 0 0 1 1 1 0 Spt20 family Robl_LC7 PF03259.17 CDJ57826.1 - 0.31 10.9 2.7 0.54 10.1 2.7 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain Guanylate_cyc_2 PF09778.9 CDJ57827.1 - 0.061 12.7 1.9 0.096 12.0 1.9 1.3 1 0 0 1 1 1 0 Guanylylate cyclase HAD_2 PF13419.6 CDJ57827.1 - 0.084 12.9 9.2 0.14 12.2 8.7 1.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LtuB PF17455.2 CDJ57827.1 - 0.5 11.0 5.3 0.35 11.5 0.4 2.6 1 1 1 2 2 2 0 Late transcription unit B P4Ha_N PF08336.11 CDJ57827.1 - 2.3 8.2 14.7 1.1 9.3 11.0 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Malate_DH PF12434.8 CDJ57827.1 - 5.6 7.1 8.3 0.39 10.8 1.1 2.9 3 0 0 3 3 3 0 Malate dehydrogenase enzyme Tic110 PF16940.5 CDJ57828.1 - 6.2 5.2 7.7 9.2 4.6 7.7 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Otopetrin PF03189.13 CDJ57829.1 - 0.00074 18.5 0.0 0.11 11.3 0.0 3.3 1 1 0 1 1 1 1 Otopetrin RAB3GAP2_N PF14655.6 CDJ57829.1 - 0.0018 17.6 1.2 0.0018 17.6 1.2 3.4 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Tub_N PF16322.5 CDJ57829.1 - 0.011 16.1 5.3 0.011 16.1 5.3 5.1 3 2 1 4 4 4 0 Tubby N-terminal RNA_pol_3_Rpc31 PF11705.8 CDJ57829.1 - 0.2 11.9 53.0 0.39 10.9 11.8 4.5 4 0 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 DUF5616 PF18481.1 CDJ57830.1 - 0.59 10.5 4.2 0.28 11.5 0.9 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5616) Hamartin PF04388.12 CDJ57830.1 - 5.3 5.6 26.7 6.4 5.3 26.7 1.1 1 0 0 1 1 1 0 Hamartin protein Exonuc_VII_L PF02601.15 CDJ57831.1 - 0.089 12.3 12.8 0.018 14.6 7.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Band_3_cyto PF07565.13 CDJ57831.1 - 0.79 9.5 8.8 5 6.9 6.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Ribosomal_60s PF00428.19 CDJ57832.1 - 0.034 14.7 4.5 0.034 14.7 4.5 4.8 5 0 0 5 5 5 0 60s Acidic ribosomal protein PP2C PF00481.21 CDJ57833.1 - 2.5e-09 37.1 0.0 1.1e-07 31.8 0.0 4.0 4 0 0 4 4 4 2 Protein phosphatase 2C GFO_IDH_MocA PF01408.22 CDJ57833.1 - 0.21 12.4 2.5 2.6 8.9 2.5 2.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Myosin_head PF00063.21 CDJ57834.1 - 6e-10 38.0 13.4 2e-05 23.1 0.1 2.4 2 1 0 2 2 2 2 Myosin head (motor domain) Lin-8 PF03353.15 CDJ57834.1 - 0.42 10.1 24.5 0.069 12.7 15.0 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 CDJ57834.1 - 0.58 10.3 22.9 3.2 7.9 8.3 3.1 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Orf78 PF06024.12 CDJ57834.1 - 0.98 9.8 8.9 4.7 7.6 4.2 3.3 3 0 0 3 3 3 0 Orf78 (ac78) Pex14_N PF04695.13 CDJ57834.1 - 1.9 9.1 31.9 0.92 10.2 0.1 3.4 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 CDJ57834.1 - 3.3 8.0 47.8 0.23 11.8 2.5 3.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_S15 PF02129.18 CDJ57834.1 - 4 6.9 10.9 1.6 8.3 5.7 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF5095 PF17016.5 CDJ57834.1 - 5.6 6.6 7.2 10 5.7 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) SR-25 PF10500.9 CDJ57834.1 - 7.1 6.2 49.6 0.34 10.5 3.2 3.3 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein Peroxin-13_N PF04088.13 CDJ57834.1 - 9.7 6.5 13.2 0.46 10.7 3.3 3.0 3 0 0 3 3 3 0 Peroxin 13, N-terminal region CDC45 PF02724.14 CDJ57835.1 - 0.11 10.8 34.1 0.12 10.6 34.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 CDJ57835.1 - 1.2 7.9 34.3 1.3 7.7 34.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 CDJ57835.1 - 1.3 8.8 37.9 1.4 8.6 37.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CDJ57835.1 - 3.2 7.7 30.6 4.1 7.3 30.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A IQ PF00612.27 CDJ57836.1 - 0.0011 18.5 20.6 0.0051 16.5 1.0 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif Activator_LAG-3 PF11498.8 CDJ57836.1 - 7.9 5.3 84.8 0.03 13.3 24.6 3.6 3 0 0 3 3 3 0 Transcriptional activator LAG-3 GYF PF02213.16 CDJ57837.1 - 5.5e-09 35.5 1.9 1.9e-08 33.8 1.9 1.9 1 0 0 1 1 1 1 GYF domain RskA PF10099.9 CDJ57837.1 - 8.5e-06 26.2 19.3 9e-05 22.8 8.4 11.1 2 1 6 9 9 9 2 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ57837.1 - 0.0021 17.3 17.0 0.0021 17.3 17.0 7.2 3 1 5 8 8 8 1 Sin-like protein conserved region WD40 PF00400.32 CDJ57838.1 - 2.8e-06 28.0 0.5 0.15 13.0 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ57838.1 - 0.023 14.7 1.3 0.023 14.7 1.3 6.5 5 1 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 ANAPC4_WD40 PF12894.7 CDJ57838.1 - 0.037 14.3 0.0 0.41 11.0 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EPL1 PF10513.9 CDJ57838.1 - 3.5 8.0 19.6 5.4 7.4 0.3 3.7 3 0 0 3 3 3 0 Enhancer of polycomb-like Utp13 PF08625.11 CDJ57839.1 - 4.2e-11 42.9 9.5 4.2e-11 42.9 9.5 3.7 2 1 1 3 3 1 1 Utp13 specific WD40 associated domain Otopetrin PF03189.13 CDJ57839.1 - 0.00011 21.1 0.0 0.00025 20.0 0.0 1.5 1 1 0 1 1 1 1 Otopetrin CCSAP PF15748.5 CDJ57839.1 - 0.015 15.5 30.6 0.09 12.9 8.4 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CDJ57839.1 - 0.14 12.0 33.7 0.84 9.4 9.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 CDJ57839.1 - 0.3 10.5 22.1 1.2 8.6 5.9 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Suf PF05843.14 CDJ57839.1 - 0.59 10.1 31.6 1.2 9.1 13.4 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EF-1_beta_acid PF10587.9 CDJ57839.1 - 0.96 10.0 12.7 10 6.7 12.7 2.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Lin-8 PF03353.15 CDJ57839.1 - 1.1 8.8 32.5 2 7.9 14.2 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Pox_Ag35 PF03286.14 CDJ57839.1 - 1.2 8.9 19.1 4 7.2 2.3 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 CDJ57839.1 - 2.7 7.7 24.8 3.2 7.4 14.5 2.9 2 1 0 2 2 2 0 FAM176 family Vfa1 PF08432.10 CDJ57839.1 - 2.7 8.3 36.9 7.3 6.9 9.9 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AbLIM_anchor PF16182.5 CDJ57839.1 - 3.7 7.3 19.5 0.31 10.8 6.9 2.3 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM ALMT PF11744.8 CDJ57839.1 - 4.1 6.1 30.3 0.55 9.0 10.4 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Connexin PF00029.19 CDJ57839.1 - 5.6 6.7 21.8 4.5 7.0 7.3 2.5 2 0 0 2 2 2 0 Connexin PA26 PF04636.13 CDJ57839.1 - 6.5 5.6 23.3 4.1 6.2 9.4 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SURF6 PF04935.12 CDJ57839.1 - 8.2 6.2 49.5 0.057 13.2 22.6 2.9 3 0 0 3 3 3 0 Surfeit locus protein 6 Nucleoside_tran PF01733.18 CDJ57839.1 - 8.2 5.7 12.4 0.079 12.3 0.5 2.2 2 0 0 2 2 2 0 Nucleoside transporter TRAP_alpha PF03896.16 CDJ57839.1 - 9.5 5.3 17.1 5.6 6.1 2.6 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit nec1 PF10379.9 CDJ57841.1 - 0.031 13.8 0.3 0.065 12.7 0.3 1.5 1 0 0 1 1 1 0 Virulence protein nec1 SID-1_RNA_chan PF13965.6 CDJ57841.1 - 0.75 8.1 6.6 1 7.7 6.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FHIPEP PF00771.20 CDJ57841.1 - 1.5 7.1 10.4 2.1 6.7 10.4 1.2 1 0 0 1 1 1 0 FHIPEP family Paramyxo_ncap PF00973.19 CDJ57841.1 - 3.1 6.6 13.8 4.9 6.0 13.8 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Membralin PF09746.9 CDJ57841.1 - 5.3 6.0 10.2 6.9 5.6 10.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein FapA PF03961.13 CDJ57841.1 - 7.9 5.0 13.0 11 4.5 13.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HSP70 PF00012.20 CDJ57842.1 - 6.9e-264 876.6 5.7 7.9e-264 876.4 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ57842.1 - 3.2e-15 55.8 0.1 5.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 CDJ57842.1 - 0.0017 17.4 0.2 0.44 9.5 0.1 2.5 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CDJ57842.1 - 0.0017 17.6 0.2 0.004 16.5 0.2 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CDJ57842.1 - 0.0057 16.4 0.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Herpes_UL25 PF01499.16 CDJ57842.1 - 0.15 10.5 0.1 0.23 9.9 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Syja_N PF02383.18 CDJ57843.1 - 2.1e-52 178.5 17.1 2.1e-52 178.5 17.1 4.6 3 1 0 3 3 3 1 SacI homology domain Presenilin PF01080.17 CDJ57843.1 - 0.00061 18.7 12.1 0.00061 18.7 12.1 7.8 5 2 1 6 6 6 1 Presenilin Caldesmon PF02029.15 CDJ57844.1 - 5e-05 22.3 35.1 5e-05 22.3 35.1 1.4 2 0 0 2 2 2 1 Caldesmon Sin_N PF04801.13 CDJ57844.1 - 0.00027 20.3 41.3 0.00048 19.5 41.3 1.4 1 0 0 1 1 1 1 Sin-like protein conserved region Borrelia_P83 PF05262.11 CDJ57844.1 - 0.017 13.6 28.7 0.018 13.6 28.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BUD22 PF09073.10 CDJ57844.1 - 0.053 12.9 48.4 0.031 13.6 41.3 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 CDJ57844.1 - 0.32 9.1 39.7 0.54 8.4 39.7 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 CDJ57844.1 - 0.38 10.7 63.4 1.1 9.2 63.4 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ57844.1 - 1.4 7.1 42.0 2 6.6 42.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S46 PF10459.9 CDJ57844.1 - 2.6 6.6 22.0 3.1 6.3 22.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Draxin PF15550.6 CDJ57844.1 - 3.1 7.6 27.1 5.2 6.9 27.1 1.3 1 0 0 1 1 1 0 Draxin Lin-8 PF03353.15 CDJ57844.1 - 4.8 6.7 49.8 14 5.2 45.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF1664 PF07889.12 CDJ57845.1 - 1.4e-05 25.1 5.1 1.6e-05 24.9 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MIS13 PF08202.11 CDJ57845.1 - 0.002 17.5 5.7 0.002 17.5 5.7 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family JIP_LZII PF16471.5 CDJ57845.1 - 0.0022 18.1 2.8 0.0023 18.0 1.9 1.5 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II GAS PF13851.6 CDJ57845.1 - 0.0062 15.9 9.5 0.0062 15.9 9.5 1.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Laminin_I PF06008.14 CDJ57845.1 - 0.014 15.1 10.9 0.015 15.0 10.9 1.0 1 0 0 1 1 1 0 Laminin Domain I Filament PF00038.21 CDJ57845.1 - 0.017 14.8 10.8 0.02 14.5 10.8 1.0 1 0 0 1 1 1 0 Intermediate filament protein GOLGA2L5 PF15070.6 CDJ57845.1 - 0.018 13.8 11.7 0.022 13.4 11.7 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 MqsA_antitoxin PF15731.5 CDJ57845.1 - 0.018 15.1 0.9 0.02 15.0 0.9 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Sigma70_ner PF04546.13 CDJ57845.1 - 0.019 14.8 6.5 0.022 14.7 6.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Spc7 PF08317.11 CDJ57845.1 - 0.022 13.7 11.6 0.026 13.4 11.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 CDJ57845.1 - 0.024 15.0 14.0 0.028 14.8 14.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 CDJ57845.1 - 0.027 14.7 7.1 0.03 14.5 7.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 CDJ57845.1 - 0.027 14.3 2.2 0.027 14.3 2.2 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain TACC_C PF05010.14 CDJ57845.1 - 0.027 14.3 13.2 0.036 13.8 13.2 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 CDJ57845.1 - 0.035 13.4 8.7 0.035 13.4 8.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2573 PF10835.8 CDJ57845.1 - 0.043 14.2 3.3 0.67 10.3 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) KxDL PF10241.9 CDJ57845.1 - 0.056 13.7 7.9 0.64 10.3 5.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Mt_ATP-synt_D PF05873.12 CDJ57845.1 - 0.07 13.0 6.5 0.12 12.2 4.7 1.8 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.12 CDJ57845.1 - 0.072 13.6 3.3 0.42 11.1 1.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CDJ57845.1 - 0.083 12.2 7.5 0.11 11.9 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 CDJ57845.1 - 0.085 12.7 8.5 0.11 12.3 8.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF641 PF04859.12 CDJ57845.1 - 0.09 13.1 8.7 0.12 12.7 8.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-H PF05837.12 CDJ57845.1 - 0.092 13.2 9.7 0.13 12.7 9.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 CDJ57845.1 - 0.099 11.9 9.7 0.11 11.8 9.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein PSII_Pbs27 PF13326.6 CDJ57845.1 - 0.11 12.8 1.3 0.13 12.6 1.3 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 YtxH PF12732.7 CDJ57845.1 - 0.12 12.9 1.4 0.27 11.8 1.4 1.7 1 1 0 1 1 1 0 YtxH-like protein Laminin_II PF06009.12 CDJ57845.1 - 0.13 12.3 4.2 0.17 11.9 4.2 1.3 1 0 0 1 1 1 0 Laminin Domain II Apolipoprotein PF01442.18 CDJ57845.1 - 0.13 12.1 12.4 0.25 11.2 12.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TipAS PF07739.13 CDJ57845.1 - 0.14 12.7 7.2 0.29 11.7 7.2 1.6 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Prefoldin PF02996.17 CDJ57845.1 - 0.15 12.0 7.3 3.3 7.6 6.5 2.2 1 1 0 1 1 1 0 Prefoldin subunit PspA_IM30 PF04012.12 CDJ57845.1 - 0.17 11.4 12.8 0.44 10.1 3.3 2.0 1 1 1 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.8 CDJ57845.1 - 0.18 11.8 11.4 0.33 11.0 7.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 CDJ57845.1 - 0.27 9.8 8.8 0.33 9.6 8.8 1.0 1 0 0 1 1 1 0 AAA domain AcylCoA_dehyd_C PF12186.8 CDJ57845.1 - 0.29 11.3 4.3 1.7 8.8 0.7 2.0 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Exonuc_VII_L PF02601.15 CDJ57845.1 - 0.37 10.3 8.3 0.41 10.2 8.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 CDJ57845.1 - 0.4 11.3 5.0 1.6 9.4 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 CDJ57845.1 - 0.44 9.6 7.5 0.52 9.3 7.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 CDJ57845.1 - 0.45 9.7 8.6 0.5 9.6 8.6 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 ADIP PF11559.8 CDJ57845.1 - 0.61 10.2 12.4 0.71 9.9 12.4 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding COG2 PF06148.11 CDJ57845.1 - 0.67 10.1 6.5 3.1 7.9 6.5 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.19 CDJ57845.1 - 0.71 9.5 11.0 4.6 6.9 11.0 1.9 1 1 0 1 1 1 0 GrpE Med9 PF07544.13 CDJ57845.1 - 0.84 9.8 11.5 1.9 8.7 11.5 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GPO PF05929.11 CDJ57845.1 - 0.88 9.1 6.7 0.98 9.0 6.7 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4446 PF14584.6 CDJ57845.1 - 1.6 8.7 5.2 2.1 8.3 4.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CREPT PF16566.5 CDJ57845.1 - 2.1 8.5 9.6 5.9 7.1 9.6 1.7 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour FapA PF03961.13 CDJ57845.1 - 2.1 6.8 7.0 2.3 6.7 7.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A USP8_interact PF08941.10 CDJ57845.1 - 2.5 7.9 9.4 0.57 10.0 4.6 1.8 1 1 1 2 2 2 0 USP8 interacting UPF0242 PF06785.11 CDJ57845.1 - 2.7 8.0 15.5 3.3 7.8 15.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YqjK PF13997.6 CDJ57845.1 - 3.9 7.8 6.9 2.5 8.4 5.4 1.5 2 0 0 2 2 1 0 YqjK-like protein ZapB PF06005.12 CDJ57845.1 - 4.2 7.9 17.4 5.4 7.5 6.6 2.1 1 1 1 2 2 2 0 Cell division protein ZapB TPX2 PF06886.11 CDJ57845.1 - 4.6 7.5 13.0 26 5.2 13.1 2.2 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) LMBR1 PF04791.16 CDJ57845.1 - 5.8 5.7 6.1 6.1 5.6 6.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein K_channel_TID PF07941.11 CDJ57848.1 - 0.024 15.1 8.1 0.024 15.1 8.1 16.7 6 3 7 13 13 13 0 Potassium channel Kv1.4 tandem inactivation domain DUF2071 PF09844.9 CDJ57848.1 - 0.031 13.9 1.2 0.12 12.0 1.2 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) UQ_con PF00179.26 CDJ57850.1 - 2.7e-33 114.6 0.0 3.7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ57850.1 - 0.054 13.8 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 CDJ57850.1 - 0.058 13.2 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 UEV domain TFIIA PF03153.13 CDJ57851.1 - 0.23 11.4 24.4 0.38 10.7 24.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3631 PF12307.8 CDJ57851.1 - 2 8.6 7.1 0.12 12.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Cation_ATPase_C PF00689.21 CDJ57852.1 - 4.8e-31 107.9 0.1 8.5e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ57852.1 - 3e-13 50.5 0.3 2.4e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ57852.1 - 1.7e-05 24.7 0.7 0.00027 20.8 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ57852.1 - 0.00073 19.6 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) CAP_N PF01213.19 CDJ57852.1 - 0.008 15.7 5.1 0.017 14.7 5.1 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDJ57852.1 - 0.049 13.7 5.3 0.027 14.5 2.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4887 PF16228.5 CDJ57852.1 - 0.48 10.6 7.4 0.85 9.8 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) SRP68 PF16969.5 CDJ57853.1 - 1.7e-14 53.8 13.9 1.7e-14 53.8 13.9 2.5 3 0 0 3 3 3 2 RNA-binding signal recognition particle 68 SR-25 PF10500.9 CDJ57853.1 - 0.0043 16.7 1.6 0.0085 15.7 1.6 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF588 PF04535.12 CDJ57853.1 - 6.4 6.6 16.0 0.12 12.1 1.9 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF588) DUF2057 PF09829.9 CDJ57854.1 - 1.9 8.6 11.1 0.1 12.7 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) RskA PF10099.9 CDJ57856.1 - 0.0042 17.4 0.4 0.0042 17.4 0.4 10.0 2 2 5 8 8 8 3 Anti-sigma-K factor rskA Peptidase_M22 PF00814.25 CDJ57857.1 - 8.8e-06 25.6 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 Glycoprotease family Motile_Sperm PF00635.26 CDJ57858.1 - 3.2e-19 68.8 0.0 5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain 14-3-3 PF00244.20 CDJ57860.1 - 3e-11 43.3 1.2 9.4e-07 28.6 0.1 3.0 4 0 0 4 4 3 2 14-3-3 protein Spt20 PF12090.8 CDJ57860.1 - 0.014 15.0 6.6 0.014 15.0 6.6 2.8 2 1 0 2 2 1 0 Spt20 family CNDH2_C PF16858.5 CDJ57860.1 - 0.027 14.4 6.7 2.9 7.7 4.2 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RAP1 PF07218.11 CDJ57860.1 - 0.088 11.1 3.1 0.12 10.6 3.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PNISR PF15996.5 CDJ57860.1 - 0.09 13.0 7.9 2.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Nop25 PF09805.9 CDJ57860.1 - 0.12 12.8 6.4 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Apt1 PF10351.9 CDJ57860.1 - 0.21 10.4 11.0 0.024 13.5 2.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain CPSF100_C PF13299.6 CDJ57860.1 - 0.23 11.6 10.1 0.4 10.9 1.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AF-4 PF05110.13 CDJ57860.1 - 0.54 8.3 26.1 1.1 7.2 3.0 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF2052 PF09747.9 CDJ57860.1 - 0.74 9.9 13.8 2.8 8.0 2.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.15 CDJ57860.1 - 1.7 8.1 13.1 1.1 8.8 1.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PDCD2_C PF04194.13 CDJ57860.1 - 2.7 8.0 11.0 0.18 11.9 3.2 2.3 2 1 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Apc15p PF05841.11 CDJ57860.1 - 4.8 8.0 18.4 1.4 9.7 3.8 2.8 2 1 1 3 3 3 0 Apc15p protein FAM176 PF14851.6 CDJ57860.1 - 6.2 6.5 10.4 11 5.7 1.0 2.4 2 1 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.16 CDJ57860.1 - 7.4 6.6 9.6 9.2 6.2 2.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 CDJ57860.1 - 9.7 6.0 15.5 9.6 6.0 1.1 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Trehalose_PPase PF02358.16 CDJ57861.1 - 9.3e-38 129.7 0.0 2.1e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase DUF2722 PF10846.8 CDJ57861.1 - 0.32 9.9 0.0 0.32 9.9 0.0 6.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2722) NAD_binding_1 PF00175.21 CDJ57862.1 - 9.6e-12 45.5 9.6 3.1e-11 43.9 0.1 4.5 4 1 0 4 4 4 1 Oxidoreductase NAD-binding domain RAB3GAP2_N PF14655.6 CDJ57862.1 - 5.3e-05 22.7 0.2 5.3e-05 22.7 0.2 5.3 5 1 1 6 6 6 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Flavodoxin_1 PF00258.25 CDJ57862.1 - 5.7e-05 23.3 1.2 0.001 19.3 1.2 3.0 1 1 0 1 1 1 1 Flavodoxin EntA_Immun PF08951.10 CDJ57862.1 - 0.83 10.1 10.0 0.063 13.7 2.4 3.0 3 0 0 3 3 3 0 Enterocin A Immunity GRASP55_65 PF04495.14 CDJ57863.1 - 1.3e-34 119.5 0.0 2.1e-29 102.6 0.0 2.4 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain AAA_23 PF13476.6 CDJ57863.1 - 0.0011 19.5 7.5 0.0018 18.8 7.5 1.3 1 0 0 1 1 1 1 AAA domain Neur_chan_memb PF02932.16 CDJ57863.1 - 0.0078 16.3 1.7 0.011 15.8 1.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CDJ57863.1 - 0.016 14.3 3.9 0.021 13.8 3.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 CDJ57863.1 - 0.017 13.9 3.7 0.032 13.0 3.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 CDJ57863.1 - 0.025 13.3 8.3 0.036 12.8 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 CDJ57863.1 - 0.038 12.1 3.4 0.046 11.8 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1676 PF07898.13 CDJ57863.1 - 0.059 13.4 4.5 0.1 12.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Bul1_N PF04425.12 CDJ57863.1 - 0.14 10.9 5.6 0.25 10.1 5.6 1.3 1 0 0 1 1 1 0 Bul1 N terminus Serinc PF03348.15 CDJ57863.1 - 0.2 10.5 1.8 0.29 10.0 1.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) LMBR1 PF04791.16 CDJ57863.1 - 0.22 10.4 0.6 0.26 10.2 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hydin_ADK PF17213.3 CDJ57863.1 - 0.24 11.7 7.0 19 5.4 6.4 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3391 PF11871.8 CDJ57863.1 - 0.65 10.5 15.0 7 7.2 8.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) GerA PF03323.13 CDJ57863.1 - 0.78 8.1 4.4 1.1 7.6 4.4 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF2126 PF09899.9 CDJ57863.1 - 0.98 7.4 5.7 1.4 6.9 5.7 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) eIF-3_zeta PF05091.12 CDJ57863.1 - 2 7.3 15.1 3.6 6.4 15.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CDJ57863.1 - 4.3 6.7 13.4 0.11 12.0 7.1 1.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 CDJ57863.1 - 5 4.9 11.7 7.6 4.3 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 CDJ57863.1 - 6.1 5.0 22.5 0.65 8.2 18.2 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 CDJ57863.1 - 6.8 5.4 9.9 10 4.8 9.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter BRF1 PF07741.13 CDJ57863.1 - 7.1 7.0 17.9 7.4 7.0 14.4 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ureide_permease PF07168.11 CDJ57863.1 - 7.8 5.1 6.2 15 4.2 6.2 1.4 1 0 0 1 1 1 0 Ureide permease FAM176 PF14851.6 CDJ57863.1 - 8.2 6.1 7.4 1.8 8.2 4.1 1.5 2 0 0 2 2 2 0 FAM176 family Mito_fiss_reg PF05308.11 CDJ57863.1 - 9 6.3 17.8 1.9 8.5 2.5 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2722 PF10846.8 CDJ57864.1 - 0.0065 15.5 0.1 0.0065 15.5 0.1 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF2722) PIG-U PF06728.13 CDJ57864.1 - 0.081 12.0 0.8 0.36 9.8 0.3 2.3 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Glyco_transf_20 PF00982.21 CDJ57865.1 - 1.8e-87 294.0 0.2 3.9e-68 230.3 0.0 7.7 9 0 0 9 9 9 3 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ57865.1 - 1.7e-06 27.4 0.4 0.00055 19.1 0.1 3.0 2 0 0 2 2 2 2 Trehalose-phosphatase Med26 PF08711.11 CDJ57866.1 - 3.6e-07 30.1 0.2 3.6e-07 30.1 0.2 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Zip PF02535.22 CDJ57866.1 - 0.00079 18.7 4.0 0.00092 18.5 4.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Serglycin PF04360.12 CDJ57866.1 - 0.001 19.0 0.2 0.001 19.0 0.2 1.7 2 0 0 2 2 2 1 Serglycin CDC45 PF02724.14 CDJ57866.1 - 1.8 6.7 21.9 0.047 12.0 13.4 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF2052 PF09747.9 CDJ57866.1 - 6.9 6.8 31.2 0.29 11.3 17.8 2.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) HSP70 PF00012.20 CDJ57867.1 - 1.1e-257 856.1 10.9 1.3e-257 855.8 10.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ57867.1 - 2.7e-19 69.2 1.9 2.3e-18 66.1 0.8 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CDJ57867.1 - 0.00091 19.6 3.2 0.42 11.1 0.1 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 CDJ57867.1 - 0.0022 17.3 0.6 0.0047 16.3 0.6 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 FGGY_C PF02782.16 CDJ57867.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CDJ57867.1 - 0.015 14.3 0.4 2.2 7.2 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CDJ57867.1 - 0.13 11.5 0.8 0.77 9.0 0.1 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SIKE PF05769.11 CDJ57867.1 - 0.55 10.1 4.4 0.15 12.0 0.8 1.8 2 0 0 2 2 2 0 SIKE family Sin_N PF04801.13 CDJ57868.1 - 3.9e-59 201.0 33.3 8.4e-30 104.3 32.6 3.5 2 1 0 2 2 2 2 Sin-like protein conserved region RskA PF10099.9 CDJ57868.1 - 8.1e-08 32.8 0.0 8.1e-08 32.8 0.0 6.1 2 2 3 5 5 5 1 Anti-sigma-K factor rskA XPG_I PF00867.18 CDJ57869.1 - 2.9e-12 46.7 0.6 2.9e-12 46.7 0.6 3.6 3 0 0 3 3 3 1 XPG I-region K_channel_TID PF07941.11 CDJ57869.1 - 0.02 15.3 2.4 0.02 15.3 2.4 15.7 8 4 5 13 13 13 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ57869.1 - 0.072 13.4 0.1 0.072 13.4 0.1 10.9 2 2 7 9 9 9 0 Anti-sigma-K factor rskA SH3_1 PF00018.28 CDJ57870.1 - 4.8e-06 26.1 0.0 0.00051 19.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDJ57870.1 - 0.0044 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDJ57870.1 - 0.0045 16.8 0.1 0.012 15.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain Spt20 PF12090.8 CDJ57872.1 - 0.0053 16.4 7.8 0.0053 16.4 7.8 1.6 2 0 0 2 2 2 1 Spt20 family SARAF PF06682.12 CDJ57872.1 - 0.0058 16.3 3.0 0.0058 16.3 3.0 1.7 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis NIF PF03031.18 CDJ57872.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SUIM_assoc PF16619.5 CDJ57872.1 - 0.011 15.8 4.9 0.011 15.8 4.9 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SpoIIIAH PF12685.7 CDJ57872.1 - 6 6.6 22.2 1.1 9.0 3.4 2.9 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF1645 PF07816.11 CDJ57872.1 - 6.2 7.4 20.0 0.037 14.6 8.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) Lin-8 PF03353.15 CDJ57872.1 - 9.7 5.7 8.8 18 4.7 8.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA PF00004.29 CDJ57873.1 - 1.5e-28 99.8 0.1 9e-28 97.3 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ57873.1 - 1.3e-09 37.7 0.2 3.7e-09 36.2 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CDJ57873.1 - 3.7e-05 23.5 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDJ57873.1 - 0.00031 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 CDJ57873.1 - 0.00058 19.6 0.7 0.67 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CDJ57873.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 3.9 2 2 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ57873.1 - 0.0017 18.6 6.0 0.02 15.2 0.0 3.7 2 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDJ57873.1 - 0.002 18.1 0.1 0.014 15.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDJ57873.1 - 0.0041 17.0 0.1 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 CDJ57873.1 - 0.0063 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CDJ57873.1 - 0.007 15.8 0.2 0.03 13.7 0.2 2.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDJ57873.1 - 0.023 14.9 0.0 0.023 14.9 0.0 2.8 3 1 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 CDJ57873.1 - 0.025 14.3 0.2 0.025 14.3 0.2 2.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_2 PF07724.14 CDJ57873.1 - 0.032 14.4 0.0 0.36 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) ResIII PF04851.15 CDJ57873.1 - 0.045 13.8 0.2 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CDJ57873.1 - 0.05 13.3 0.6 0.21 11.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ57873.1 - 0.053 14.1 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CDJ57873.1 - 0.057 13.3 0.5 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 CDJ57873.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ57873.1 - 0.062 12.5 1.7 0.64 9.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 CDJ57873.1 - 0.083 12.4 3.3 1.7 8.2 0.1 3.2 2 2 1 3 3 3 0 AAA domain AAA_28 PF13521.6 CDJ57873.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.7 3 1 0 4 4 4 0 AAA domain Torsin PF06309.11 CDJ57873.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.22 CDJ57873.1 - 0.13 12.7 0.0 0.66 10.4 0.0 2.2 2 0 0 2 2 1 0 RNA helicase HPIP PF15226.6 CDJ57873.1 - 0.2 12.0 1.6 0.54 10.7 1.6 1.7 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Zeta_toxin PF06414.12 CDJ57873.1 - 0.21 10.9 4.5 0.47 9.7 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 CDJ57873.1 - 0.3 10.8 0.0 0.3 10.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain RskA PF10099.9 CDJ57874.1 - 3.7 7.8 54.9 0.07 13.4 10.6 4.2 2 1 2 4 4 4 0 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ57874.1 - 8.5 4.8 27.8 99 1.3 27.8 2.0 1 1 0 1 1 1 0 Utp14 protein RskA PF10099.9 CDJ57875.1 - 9.9e-12 45.5 3.4 1.4e-06 28.7 0.4 13.1 3 2 7 11 11 11 4 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ57875.1 - 9.1e-05 22.2 19.3 9.1e-05 22.2 19.3 9.7 7 3 3 11 11 11 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ57875.1 - 0.0011 18.0 10.4 0.0011 18.0 10.4 8.2 6 3 1 7 7 7 2 Protein of unknown function (DUF2722) ESM4 PF15952.5 CDJ57875.1 - 0.01 16.3 3.5 0.01 16.3 3.5 7.0 5 1 1 7 7 7 0 Enhancer of split M4 family PIP5K PF01504.18 CDJ57876.1 - 2e-74 250.3 0.0 2e-74 250.3 0.0 4.8 3 2 0 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.32 CDJ57876.1 - 0.0017 17.8 0.3 0.0053 16.2 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ57876.1 - 0.031 14.2 0.3 0.1 12.6 0.3 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 CDJ57876.1 - 0.04 14.4 0.3 0.15 12.5 0.3 2.0 1 1 0 1 1 1 0 EF-hand domain pair Caldesmon PF02029.15 CDJ57876.1 - 0.045 12.5 58.9 0.079 11.7 58.9 1.3 1 0 0 1 1 1 0 Caldesmon EF-hand_8 PF13833.6 CDJ57876.1 - 0.077 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair PAT1 PF09770.9 CDJ57876.1 - 9.8 4.3 85.3 1.7 6.8 18.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HSP70 PF00012.20 CDJ57877.1 - 5.1e-25 87.7 2.9 5.1e-25 87.7 2.9 6.3 2 2 4 6 6 6 1 Hsp70 protein SUIM_assoc PF16619.5 CDJ57877.1 - 0.01 15.9 2.0 0.01 15.9 2.0 10.4 7 3 1 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 Se-cys_synth_N PF12390.8 CDJ57877.1 - 2.2 8.6 5.3 24 5.2 2.7 3.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal WD40 PF00400.32 CDJ57878.1 - 1.6e-36 123.7 25.6 1e-06 29.4 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57878.1 - 5.1e-16 58.7 6.1 0.0048 17.2 0.1 5.0 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CDJ57878.1 - 6.2e-06 25.5 4.0 0.12 11.4 2.7 3.5 3 1 1 4 4 4 2 Coatomer WD associated region Nbas_N PF15492.6 CDJ57878.1 - 0.00017 21.0 0.5 0.0013 18.1 0.4 2.5 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 CDJ57878.1 - 0.0011 17.9 6.4 0.11 11.5 0.1 3.8 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 CDJ57878.1 - 0.024 13.4 5.2 0.02 13.6 1.3 2.5 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Presenilin PF01080.17 CDJ57878.1 - 0.025 13.3 14.0 0.013 14.3 9.4 2.0 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 CDJ57878.1 - 0.062 12.3 7.0 3.2 6.7 8.1 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF4050 PF13259.6 CDJ57878.1 - 0.16 12.3 11.0 1.3 9.3 8.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Nucleoporin_N PF08801.11 CDJ57878.1 - 0.17 10.6 1.0 3.3 6.4 0.0 2.5 2 1 0 3 3 3 0 Nup133 N terminal like NLPC_P60 PF00877.19 CDJ57878.1 - 0.18 11.8 3.9 5.3 7.1 0.5 3.1 3 0 0 3 3 3 0 NlpC/P60 family Afi1 PF07792.12 CDJ57878.1 - 0.23 12.0 14.0 0.98 9.9 6.3 3.1 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PEX11 PF05648.14 CDJ57878.1 - 0.26 10.7 4.6 0.67 9.4 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) RAB3GAP2_N PF14655.6 CDJ57878.1 - 0.6 9.3 19.5 0.12 11.6 1.3 3.5 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MAGE PF01454.19 CDJ57878.1 - 0.65 9.7 6.0 0.54 9.9 0.1 2.8 3 0 0 3 3 3 0 MAGE family Spt20 PF12090.8 CDJ57878.1 - 0.73 9.4 37.4 0.24 11.0 13.4 2.9 3 0 0 3 3 3 0 Spt20 family EPL1 PF10513.9 CDJ57878.1 - 1.4 9.3 15.9 0.39 11.1 5.4 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF913 PF06025.12 CDJ57878.1 - 1.7 7.6 6.9 2.7 6.9 4.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) KCT2 PF17818.1 CDJ57878.1 - 3.6 7.7 6.5 19 5.3 0.0 2.2 2 0 0 2 2 2 0 Keratinocyte-associated gene product AIF_C PF14721.6 CDJ57878.1 - 4 7.8 16.3 2.1 8.7 3.1 3.2 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TRAP_alpha PF03896.16 CDJ57878.1 - 4.5 6.4 11.4 2 7.5 2.9 2.8 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit U3_snoRNA_assoc PF08297.11 CDJ57878.1 - 8.6 7.2 13.3 0.33 11.7 2.3 2.9 3 0 0 3 3 3 0 U3 snoRNA associated HA2 PF04408.23 CDJ57878.1 - 9.1 6.6 13.8 3.9 7.8 2.1 3.3 3 0 0 3 3 3 0 Helicase associated domain (HA2) AAA PF00004.29 CDJ57879.1 - 1.8e-48 164.3 0.4 3.6e-25 88.9 0.0 5.4 4 2 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ57879.1 - 1e-11 44.4 8.5 2.2e-09 37.0 0.0 3.2 3 0 0 3 3 2 2 AAA+ lid domain AAA_5 PF07728.14 CDJ57879.1 - 5.5e-11 42.6 0.0 0.00079 19.4 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ57879.1 - 7.1e-10 38.9 0.0 0.0021 17.8 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 CDJ57879.1 - 5.7e-09 35.9 0.0 0.00088 19.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CDJ57879.1 - 1.5e-08 34.3 0.0 0.0022 17.4 0.0 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ57879.1 - 2.6e-08 34.2 1.2 0.003 17.9 0.0 3.3 3 0 0 3 3 2 2 RNA helicase TIP49 PF06068.13 CDJ57879.1 - 3.6e-07 29.7 0.0 0.02 14.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 CDJ57879.1 - 1.7e-06 28.1 0.5 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 CDJ57879.1 - 5.9e-05 23.6 11.3 0.028 15.0 0.0 4.4 4 1 0 4 4 2 2 AAA domain AAA_22 PF13401.6 CDJ57879.1 - 7.3e-05 23.1 11.1 0.04 14.2 0.0 4.4 4 1 0 4 4 3 2 AAA domain AAA_2 PF07724.14 CDJ57879.1 - 9.1e-05 22.6 8.2 0.0027 17.9 0.0 5.0 5 0 0 5 5 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ57879.1 - 0.00017 22.1 1.9 0.00017 22.1 1.9 6.7 3 3 1 4 4 3 2 AAA ATPase domain TsaE PF02367.17 CDJ57879.1 - 0.00038 20.4 0.1 0.26 11.3 0.0 3.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CDJ57879.1 - 0.00055 19.8 0.0 0.47 10.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ57879.1 - 0.00078 19.2 0.1 1.9 8.2 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 CDJ57879.1 - 0.00087 18.8 0.1 0.4 10.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CDJ57879.1 - 0.0012 18.9 0.0 0.26 11.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain CDC45 PF02724.14 CDJ57879.1 - 0.0023 16.3 9.3 0.0023 16.3 9.3 5.8 5 1 0 5 5 4 2 CDC45-like protein AAA_24 PF13479.6 CDJ57879.1 - 0.0036 17.0 4.2 0.59 9.8 0.0 4.0 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.6 CDJ57879.1 - 0.0037 16.9 0.6 4.2 6.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CDJ57879.1 - 0.01 15.7 7.1 0.62 10.0 0.1 3.7 3 1 0 3 3 3 0 NACHT domain DDHD PF02862.17 CDJ57879.1 - 0.011 15.9 0.2 0.011 15.9 0.2 7.4 3 1 1 5 5 4 0 DDHD domain AAA_33 PF13671.6 CDJ57879.1 - 0.011 15.9 0.0 0.011 15.9 0.0 6.2 6 3 0 6 6 5 0 AAA domain AAA_17 PF13207.6 CDJ57879.1 - 0.015 15.7 6.3 2.3 8.7 0.0 4.5 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.6 CDJ57879.1 - 0.038 14.2 0.2 0.038 14.2 0.2 6.5 4 3 1 5 5 4 0 AAA domain NTPase_1 PF03266.15 CDJ57879.1 - 0.067 13.1 0.0 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 CDJ57879.1 - 0.067 12.5 0.0 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 CDJ57879.1 - 0.075 12.9 0.2 10 6.0 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Vps4_C PF09336.10 CDJ57879.1 - 0.089 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 CDJ57879.1 - 0.15 11.8 4.4 0.45 10.2 0.0 3.4 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase SARAF PF06682.12 CDJ57880.1 - 0.55 9.8 4.2 0.19 11.4 0.3 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SOG2 PF10428.9 CDJ57880.1 - 1.3 8.1 9.0 1.5 8.0 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.9 CDJ57881.1 - 0.00052 19.7 5.4 0.00072 19.2 5.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein K_channel_TID PF07941.11 CDJ57881.1 - 0.047 14.2 2.3 0.1 13.1 2.3 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Period_C PF12114.8 CDJ57881.1 - 0.99 9.0 11.8 1.6 8.3 11.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Gastrin PF00918.17 CDJ57881.1 - 1.1 10.3 5.1 0.39 11.7 0.7 2.2 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Macoilin PF09726.9 CDJ57881.1 - 1.6 7.2 4.5 1.8 7.0 4.5 1.1 1 0 0 1 1 1 0 Macoilin family PHD PF00628.29 CDJ57882.1 - 1.1e-06 28.4 3.3 7.6e-06 25.7 0.7 2.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CDJ57882.1 - 0.0075 15.9 0.3 0.0075 15.9 0.3 4.0 3 1 0 3 3 3 1 PHD/FYVE-zinc-finger like domain RskA PF10099.9 CDJ57882.1 - 0.025 14.9 0.0 0.025 14.9 0.0 9.6 5 3 4 9 9 9 0 Anti-sigma-K factor rskA PHD_2 PF13831.6 CDJ57882.1 - 0.037 13.6 0.8 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 PHD-finger DUF3390 PF11870.8 CDJ57882.1 - 0.065 13.6 0.5 0.34 11.3 0.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Prok-RING_1 PF14446.6 CDJ57882.1 - 0.095 12.6 4.1 0.07 13.1 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-piccolo PF05715.13 CDJ57882.1 - 0.53 10.5 0.0 0.53 10.5 0.0 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger TFIIA PF03153.13 CDJ57883.1 - 9e-06 25.9 20.1 1.1e-05 25.6 20.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 CDJ57883.1 - 0.00091 19.5 9.7 0.0016 18.7 9.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 CDJ57883.1 - 0.002 17.6 18.1 0.0028 17.1 18.1 1.1 1 0 0 1 1 1 1 BUD22 Granin PF01271.17 CDJ57883.1 - 0.021 13.8 18.1 0.033 13.1 18.1 1.2 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) Spem1 PF15670.5 CDJ57883.1 - 0.022 14.4 0.7 0.038 13.6 0.7 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Nop25 PF09805.9 CDJ57883.1 - 0.034 14.6 16.6 0.067 13.7 16.6 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CAF1 PF04857.20 CDJ57883.1 - 0.035 13.3 1.9 0.043 13.0 1.9 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Ribosomal_60s PF00428.19 CDJ57883.1 - 0.041 14.5 19.0 0.041 14.5 19.0 6.4 4 2 0 4 4 2 0 60s Acidic ribosomal protein PIN_8 PF18476.1 CDJ57883.1 - 0.055 13.3 7.1 0.083 12.7 7.1 1.2 1 0 0 1 1 1 0 PIN like domain DDRGK PF09756.9 CDJ57883.1 - 0.11 12.0 18.6 0.18 11.4 18.6 1.2 1 0 0 1 1 1 0 DDRGK domain NOA36 PF06524.12 CDJ57883.1 - 0.11 11.7 8.6 0.17 11.1 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4667 PF15700.5 CDJ57883.1 - 0.22 11.6 20.7 1.1 9.4 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Cwf_Cwc_15 PF04889.12 CDJ57883.1 - 0.22 11.2 17.6 0.13 11.9 13.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CDJ57883.1 - 0.24 11.0 30.2 0.28 10.7 6.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4148 PF13663.6 CDJ57883.1 - 0.49 10.6 0.0 0.49 10.6 0.0 6.1 4 2 2 6 6 3 0 Domain of unknown function (DUF4148) CENP-B_dimeris PF09026.10 CDJ57883.1 - 0.86 10.0 6.4 2 8.9 6.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hamartin PF04388.12 CDJ57883.1 - 2.8 6.5 15.7 4.3 5.9 15.7 1.2 1 0 0 1 1 1 0 Hamartin protein Spt5_N PF11942.8 CDJ57883.1 - 3 8.9 20.3 1.5 9.8 5.6 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PPP4R2 PF09184.11 CDJ57883.1 - 3.1 7.3 14.8 0.52 9.8 8.8 2.0 2 0 0 2 2 2 0 PPP4R2 SARAF PF06682.12 CDJ57883.1 - 4.5 6.8 19.6 0.39 10.3 13.6 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ57883.1 - 7.3 6.1 21.2 0.55 9.8 14.4 2.1 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 CDJ57883.1 - 8.3 4.2 9.4 13 3.6 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4342 PF14242.6 CDJ57883.1 - 8.6 6.4 0.0 8.6 6.4 0.0 4.2 4 0 0 4 4 2 0 Domain of unknown function (DUF4342) DUF4820 PF16091.5 CDJ57883.1 - 9.1 5.6 17.1 0.29 10.5 10.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CN_hydrolase PF00795.22 CDJ57884.1 - 3.5e-05 23.3 0.1 9.4e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Spt20 PF12090.8 CDJ57884.1 - 0.026 14.2 38.4 0.29 10.7 19.5 2.1 2 0 0 2 2 2 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ57884.1 - 1.1 10.2 34.8 0.23 12.3 6.4 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF775 PF05603.12 CDJ57884.1 - 1.9 8.0 14.7 0.24 10.9 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Suf PF05843.14 CDJ57884.1 - 9.2 6.2 18.8 2.4 8.1 2.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Kelch_1 PF01344.25 CDJ57885.1 - 1.4e-48 162.2 6.5 9e-08 31.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDJ57885.1 - 2.7e-32 110.0 5.5 4e-05 23.8 0.1 6.2 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CDJ57885.1 - 8e-19 67.4 0.0 0.0029 17.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ57885.1 - 4.3e-16 58.2 0.1 0.014 15.3 0.0 5.3 4 1 0 4 4 4 4 Kelch motif BTB_2 PF02214.22 CDJ57885.1 - 2.9e-15 56.4 0.0 8.6e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 CDJ57885.1 - 1.8e-13 50.4 3.2 0.0033 17.7 0.1 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ57885.1 - 2.7e-09 36.8 3.4 0.051 13.6 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Spermine_synth PF01564.17 CDJ57885.1 - 0.17 11.2 0.0 32 3.8 0.1 3.0 3 0 0 3 3 3 0 Spermine/spermidine synthase domain FapA PF03961.13 CDJ57885.1 - 3.3 6.2 10.9 4.7 5.7 10.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Band_3_cyto PF07565.13 CDJ57885.1 - 3.3 7.4 7.7 5.1 6.8 7.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Androgen_recep PF02166.16 CDJ57886.1 - 3.7 6.3 11.3 4.2 6.1 11.3 1.0 1 0 0 1 1 1 0 Androgen receptor rRNA_processing PF08524.11 CDJ57887.1 - 1e-07 32.1 45.1 1e-07 32.1 45.1 3.2 1 1 2 3 3 3 1 rRNA processing Caldesmon PF02029.15 CDJ57887.1 - 0.006 15.4 61.4 0.0098 14.7 61.4 1.3 1 0 0 1 1 1 1 Caldesmon LAP1C PF05609.12 CDJ57887.1 - 4.3 6.3 36.1 6.4 5.7 36.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Dapper PF15268.6 CDJ57887.1 - 5.2 5.8 32.2 6.4 5.5 32.2 1.1 1 0 0 1 1 1 0 Dapper eRF1_3 PF03465.15 CDJ57888.1 - 1.8e-10 41.3 0.1 2.1e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 eRF1 domain 3 Fumble PF03630.14 CDJ57889.1 - 4.1e-62 210.3 0.0 5.3e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Fumble Coatomer_WDAD PF04053.14 CDJ57889.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Fumble PF03630.14 CDJ57890.1 - 0.0024 17.1 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Fumble DUF4964 PF16334.5 CDJ57890.1 - 0.092 12.3 0.2 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) SR-25 PF10500.9 CDJ57892.1 - 0.0013 18.3 8.2 0.0013 18.3 8.2 17.0 15 2 2 17 17 17 3 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CDJ57892.1 - 1.8 7.9 0.0 1.8 7.9 0.0 3.8 4 0 0 4 4 4 0 Protein kinase domain WBS_methylT PF12589.8 CDJ57893.1 - 1.4e-11 44.9 11.0 1.4e-11 44.9 11.0 2.4 2 1 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Ribosomal_60s PF00428.19 CDJ57893.1 - 0.0011 19.5 6.8 0.002 18.7 6.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Spt5_N PF11942.8 CDJ57893.1 - 1.7 9.6 11.4 0.075 14.0 5.1 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Spt20 PF12090.8 CDJ57894.1 - 1.7e-07 31.1 67.5 0.00099 18.8 4.3 4.4 4 0 0 4 4 4 3 Spt20 family RskA PF10099.9 CDJ57894.1 - 0.00024 21.4 1.6 0.00024 21.4 1.6 6.8 1 1 2 4 4 4 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ57894.1 - 0.0075 15.9 6.9 0.0075 15.9 6.9 5.3 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein Arv1 PF04161.13 CDJ57894.1 - 1.3 9.1 4.0 4.3 7.5 0.1 2.7 2 1 0 2 2 2 0 Arv1-like family ParA PF10609.9 CDJ57895.1 - 1.2e-46 159.1 0.1 2.1e-46 158.4 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDJ57895.1 - 1.7e-08 34.6 0.0 3.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ57895.1 - 6.8e-08 32.6 0.0 4.7e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CDJ57895.1 - 9.6e-06 25.1 0.0 0.00016 21.1 0.0 2.4 2 1 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 CDJ57895.1 - 3.3e-05 23.2 1.9 8.4e-05 21.9 0.0 2.3 3 0 0 3 3 3 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CDJ57895.1 - 0.00065 19.3 2.8 0.0011 18.6 0.1 2.4 2 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Spt20 PF12090.8 CDJ57895.1 - 0.0019 17.9 6.7 0.0036 16.9 6.7 1.4 1 0 0 1 1 1 1 Spt20 family NB-ARC PF00931.22 CDJ57895.1 - 0.0027 16.9 0.1 0.0027 16.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain TFIIA PF03153.13 CDJ57895.1 - 0.0034 17.5 5.4 0.0043 17.1 5.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RsgA_GTPase PF03193.16 CDJ57895.1 - 0.0053 16.7 0.1 0.0053 16.7 0.1 2.1 3 0 0 3 3 2 1 RsgA GTPase DUF4094 PF13334.6 CDJ57895.1 - 0.0069 16.8 1.7 0.049 14.0 1.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4094) LapA_dom PF06305.11 CDJ57895.1 - 0.01 15.6 0.8 0.01 15.6 0.8 1.9 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain MeaB PF03308.16 CDJ57895.1 - 0.013 14.5 0.6 0.033 13.2 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CDJ57895.1 - 0.017 14.7 0.3 0.041 13.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CDJ57895.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Galanin PF01296.18 CDJ57895.1 - 0.04 13.9 0.4 0.094 12.7 0.4 1.7 1 0 0 1 1 1 0 Galanin DUF2722 PF10846.8 CDJ57895.1 - 0.064 12.2 4.7 0.088 11.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) AAA_18 PF13238.6 CDJ57895.1 - 0.088 13.4 0.2 0.088 13.4 0.2 1.8 2 1 0 2 2 1 0 AAA domain Rad17 PF03215.15 CDJ57895.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain KTI12 PF08433.10 CDJ57895.1 - 0.14 11.6 1.2 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 CDJ57895.1 - 0.16 11.8 0.2 0.27 11.1 0.2 1.3 1 0 0 1 1 1 0 NTPase Arch_flagellin PF01917.16 CDJ57895.1 - 0.22 11.7 5.5 2.7 8.2 0.8 2.3 2 0 0 2 2 2 0 Archaebacterial flagellin IstB_IS21 PF01695.17 CDJ57895.1 - 0.37 10.5 1.4 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein CcmD PF04995.14 CDJ57895.1 - 0.64 10.2 4.8 1.5 8.9 4.8 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2681 PF10883.8 CDJ57895.1 - 0.69 10.4 12.4 2.4 8.6 7.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2489 PF10675.9 CDJ57895.1 - 2 8.3 11.0 0.15 12.0 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) ApoL PF05461.11 CDJ57895.1 - 3.2 7.0 10.2 0.16 11.3 2.1 2.0 2 0 0 2 2 2 0 Apolipoprotein L RskA PF10099.9 CDJ57895.1 - 4.4 7.6 28.6 0.4 10.9 9.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA IMUP PF15761.5 CDJ57896.1 - 0.018 15.7 6.0 0.018 15.7 6.0 4.0 4 0 0 4 4 4 0 Immortalisation up-regulated protein SUIM_assoc PF16619.5 CDJ57896.1 - 0.028 14.5 0.4 0.028 14.5 0.4 8.7 8 1 0 8 8 8 0 Unstructured region C-term to UIM in Ataxin3 DUF4366 PF14283.6 CDJ57896.1 - 0.055 13.5 0.4 0.055 13.5 0.4 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4366) Spt20 PF12090.8 CDJ57897.1 - 0.0006 19.5 3.3 0.0006 19.5 3.3 9.3 5 2 3 8 8 8 2 Spt20 family RskA PF10099.9 CDJ57897.1 - 0.009 16.3 9.2 0.009 16.3 9.2 9.5 3 2 4 7 7 7 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ57897.1 - 0.0099 15.5 15.2 0.0099 15.5 15.2 6.4 5 1 0 6 6 6 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ57897.1 - 0.016 14.2 0.6 0.016 14.2 0.6 9.5 7 3 3 10 10 10 0 Protein of unknown function (DUF2722) TctB PF07331.11 CDJ57897.1 - 0.044 14.1 0.0 0.15 12.3 0.0 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Fra10Ac1 PF09725.9 CDJ57898.1 - 7.7e-12 45.4 8.2 1.7e-10 41.0 8.2 2.4 1 1 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 NUDE_C PF04880.13 CDJ57899.1 - 0.00069 20.1 6.2 0.00069 20.1 6.2 6.9 2 1 3 7 7 7 1 NUDE protein, C-terminal conserved region Helicase_C PF00271.31 CDJ57900.1 - 3.9e-11 43.3 3.0 4.2e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PrgI PF12666.7 CDJ57900.1 - 0.03 15.0 0.4 0.05 14.3 0.4 1.3 1 0 0 1 1 1 0 PrgI family protein Spt20 PF12090.8 CDJ57900.1 - 0.089 12.4 21.5 0.19 11.3 21.5 1.5 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ57900.1 - 0.43 9.3 5.8 0.62 8.8 5.8 1.4 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 CDJ57900.1 - 1.5 9.2 20.0 2.9 8.4 20.0 1.3 1 0 0 1 1 1 0 AAA domain Med3 PF11593.8 CDJ57900.1 - 2.7 7.1 28.7 2.5 7.2 17.7 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Dapper PF15268.6 CDJ57901.1 - 1.4 7.6 76.0 0.016 14.1 49.2 2.4 2 0 0 2 2 2 0 Dapper Utp14 PF04615.13 CDJ57901.1 - 2.8 6.4 86.7 0.2 10.2 63.5 2.1 2 0 0 2 2 2 0 Utp14 protein THOC7 PF05615.13 CDJ57902.1 - 0.0032 17.7 11.9 0.0032 17.7 11.9 7.6 3 1 3 6 6 6 1 Tho complex subunit 7 Pkinase PF00069.25 CDJ57903.1 - 1.8e-51 175.1 2.1 1.1e-48 165.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ57903.1 - 2.4e-19 69.6 2.0 4.3e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ57903.1 - 2.3e-05 24.5 11.3 0.0029 17.6 11.3 3.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDK2AP PF09806.9 CDJ57903.1 - 0.0008 19.5 18.6 0.0013 18.9 18.6 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Kdo PF06293.14 CDJ57903.1 - 0.0018 17.6 0.3 0.0044 16.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BAT2_N PF07001.11 CDJ57903.1 - 0.014 15.9 20.1 0.022 15.2 20.1 1.3 1 0 0 1 1 1 0 BAT2 N-terminus Hid1 PF12722.7 CDJ57903.1 - 0.016 13.4 4.8 0.017 13.3 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 CDJ57903.1 - 0.023 13.4 8.1 0.027 13.2 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CDJ57903.1 - 0.044 12.7 2.2 0.052 12.4 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Choline_kinase PF01633.20 CDJ57903.1 - 0.085 12.4 0.1 0.085 12.4 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase CCSAP PF15748.5 CDJ57903.1 - 0.14 12.3 11.8 0.19 11.9 11.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ASD2 PF08687.11 CDJ57903.1 - 0.18 11.3 10.9 0.25 10.9 10.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SAGA-Tad1 PF12767.7 CDJ57903.1 - 0.36 10.5 8.0 0.47 10.2 8.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SLC12 PF03522.15 CDJ57903.1 - 0.54 9.2 10.6 0.76 8.7 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Smg8_Smg9 PF10220.9 CDJ57903.1 - 0.59 8.4 8.6 0.74 8.1 8.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF913 PF06025.12 CDJ57903.1 - 0.7 8.8 6.2 1.2 8.1 6.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BAF1_ABF1 PF04684.13 CDJ57903.1 - 0.76 8.8 9.7 0.99 8.4 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1676 PF07898.13 CDJ57903.1 - 0.89 9.6 2.7 1.8 8.6 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Dicty_REP PF05086.12 CDJ57903.1 - 0.95 7.4 3.0 1.2 7.0 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 CDJ57903.1 - 1.3 8.8 10.1 1.7 8.4 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CDJ57903.1 - 1.3 8.5 11.0 1.9 7.9 11.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rtf2 PF04641.12 CDJ57903.1 - 1.5 8.1 11.2 2.2 7.6 11.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Pkinase_fungal PF17667.1 CDJ57903.1 - 1.7 7.4 16.9 31 3.2 16.9 2.0 1 1 0 1 1 1 0 Fungal protein kinase Hydin_ADK PF17213.3 CDJ57903.1 - 1.7 8.9 13.6 2.6 8.3 13.6 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Menin PF05053.13 CDJ57903.1 - 1.8 6.8 11.6 2.4 6.4 11.6 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 CDJ57903.1 - 2.5 6.8 16.9 3.4 6.3 16.9 1.1 1 0 0 1 1 1 0 Presenilin MecA PF05389.12 CDJ57903.1 - 2.5 7.7 7.2 0.62 9.6 0.6 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Gti1_Pac2 PF09729.9 CDJ57903.1 - 2.6 8.1 9.1 4 7.5 9.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2828 PF11443.8 CDJ57903.1 - 3.9 5.4 8.9 5.1 5.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TAF4 PF05236.14 CDJ57903.1 - 4.1 7.1 16.4 6.3 6.5 16.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NPR3 PF03666.13 CDJ57903.1 - 4.2 6.0 10.8 5.7 5.6 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ57903.1 - 4.5 7.2 9.0 6.9 6.6 9.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PIP5K PF01504.18 CDJ57903.1 - 4.5 6.4 8.9 1.6 7.8 6.1 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Folliculin PF11704.8 CDJ57903.1 - 4.7 7.1 9.5 7.6 6.4 9.5 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Raftlin PF15250.6 CDJ57903.1 - 4.8 5.8 12.9 6.8 5.3 12.9 1.1 1 0 0 1 1 1 0 Raftlin Senescence_reg PF04520.13 CDJ57903.1 - 6.7 7.5 11.9 10 6.9 11.9 1.2 1 0 0 1 1 1 0 Senescence regulator ALMT PF11744.8 CDJ57903.1 - 9.1 5.0 9.0 13 4.5 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SRP-alpha_N PF04086.13 CDJ57903.1 - 9.1 6.1 15.7 13 5.6 15.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.9 CDJ57903.1 - 9.2 4.4 22.3 15 3.7 22.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 CDJ57903.1 - 9.4 3.2 12.3 12 2.9 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA PF00004.29 CDJ57904.1 - 1.5e-31 109.5 21.9 7.3e-22 78.2 0.5 5.8 5 1 0 5 5 3 3 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ57904.1 - 1.7e-06 27.9 0.1 0.14 11.9 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ57904.1 - 4.1e-06 27.3 9.0 0.00013 22.4 8.2 4.8 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CDJ57904.1 - 6.4e-06 26.5 12.6 0.028 14.7 0.0 5.1 4 0 0 4 4 3 3 AAA domain AAA_5 PF07728.14 CDJ57904.1 - 6.6e-06 26.2 0.2 0.22 11.5 0.1 3.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CDJ57904.1 - 3.9e-05 23.0 0.0 0.31 10.2 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDJ57904.1 - 4.3e-05 23.0 0.2 0.5 9.7 0.0 3.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_lid_3 PF17862.1 CDJ57904.1 - 7.5e-05 22.5 0.1 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 CDJ57904.1 - 0.00023 20.9 2.0 0.28 10.9 0.0 3.3 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 CDJ57904.1 - 0.00044 20.1 1.3 2.1 8.2 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 CDJ57904.1 - 0.00049 20.0 0.4 0.28 11.0 0.0 3.4 3 0 0 3 3 3 1 Bacterial dnaA protein RNA_helicase PF00910.22 CDJ57904.1 - 0.00049 20.4 2.5 0.95 9.9 0.0 3.4 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 CDJ57904.1 - 0.00078 19.0 0.4 0.6 9.6 0.0 3.1 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 CDJ57904.1 - 0.0013 18.4 3.4 3.3 7.2 0.5 3.7 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 CDJ57904.1 - 0.0047 16.3 0.2 22 4.3 0.0 3.4 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 CDJ57904.1 - 0.0078 16.6 3.1 0.11 12.9 2.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ57904.1 - 0.015 15.4 15.1 0.063 13.4 0.2 5.4 4 1 1 5 5 5 0 AAA domain TsaE PF02367.17 CDJ57904.1 - 0.026 14.5 0.0 9.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDJ57904.1 - 0.03 14.1 0.1 0.03 14.1 0.1 5.7 4 2 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 CDJ57904.1 - 0.036 14.0 0.0 30 4.4 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_2 PF07724.14 CDJ57904.1 - 0.061 13.4 15.8 0.56 10.3 0.0 6.1 5 1 0 5 5 4 0 AAA domain (Cdc48 subfamily) RskA PF10099.9 CDJ57904.1 - 0.11 12.7 0.0 0.11 12.7 0.0 7.8 3 3 2 6 6 3 0 Anti-sigma-K factor rskA AAA_24 PF13479.6 CDJ57904.1 - 0.25 11.0 0.0 0.25 11.0 0.0 4.0 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.6 CDJ57904.1 - 0.26 11.9 8.7 0.72 10.4 0.0 4.2 5 0 0 5 5 3 0 AAA domain DUF2052 PF09747.9 CDJ57904.1 - 5.8 7.0 43.2 1.5 8.9 4.2 4.0 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) SUIM_assoc PF16619.5 CDJ57905.1 - 0.00027 20.9 9.4 0.0013 18.8 0.6 15.9 11 4 2 13 13 13 2 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ57905.1 - 0.00046 19.3 5.0 0.00046 19.3 5.0 10.5 9 1 1 10 10 10 5 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ57905.1 - 0.002 17.4 17.6 0.002 17.4 17.6 16.3 12 3 2 15 15 15 1 Mediator complex subunit 3 fungal DDHD PF02862.17 CDJ57905.1 - 0.0025 18.0 4.0 0.0025 18.0 4.0 6.9 6 2 0 6 6 6 1 DDHD domain DUF2076 PF09849.9 CDJ57905.1 - 0.0038 17.3 12.5 0.0038 17.3 12.5 12.5 10 3 3 13 13 13 1 Uncharacterized protein conserved in bacteria (DUF2076) Rer1 PF03248.13 CDJ57905.1 - 3.3 7.4 5.7 4.2 7.1 0.2 3.1 2 1 0 2 2 2 0 Rer1 family GTP_EFTU PF00009.27 CDJ57906.1 - 5.5e-24 84.8 0.1 5.5e-24 84.8 0.1 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain SR-25 PF10500.9 CDJ57906.1 - 0.00042 20.0 28.9 0.37 10.4 15.9 3.2 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Dynamin_N PF00350.23 CDJ57906.1 - 0.00052 20.1 0.0 0.00052 20.1 0.0 3.5 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 CDJ57906.1 - 0.0013 18.8 2.5 0.0043 17.1 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Spt20 PF12090.8 CDJ57906.1 - 0.0092 15.6 74.3 0.16 11.6 39.8 3.3 3 0 0 3 3 3 3 Spt20 family AUX_IAA PF02309.16 CDJ57906.1 - 0.4 10.5 14.9 9.8 6.0 0.1 2.6 2 1 0 2 2 2 0 AUX/IAA family eIF3_subunit PF08597.10 CDJ57906.1 - 0.51 10.2 40.6 0.029 14.3 25.2 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit YL1 PF05764.13 CDJ57906.1 - 1.9 8.5 37.8 0.062 13.4 22.8 2.6 3 0 0 3 3 3 0 YL1 nuclear protein Draxin PF15550.6 CDJ57906.1 - 2.3 8.0 25.3 0.057 13.3 13.8 2.4 3 0 0 3 3 3 0 Draxin PRIMA1 PF16101.5 CDJ57906.1 - 5.6 7.0 15.1 0.058 13.4 6.2 2.3 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 RNA_pol_Rpb2_6 PF00562.28 CDJ57907.1 - 0.031 13.3 0.6 0.031 13.3 0.6 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 6 PAS PF00989.25 CDJ57907.1 - 2.5 8.1 5.1 0.61 10.1 0.2 2.3 2 0 0 2 2 2 0 PAS fold DUF3292 PF11696.8 CDJ57908.1 - 0.013 13.9 2.1 0.016 13.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Myc_N PF01056.18 CDJ57908.1 - 0.017 15.0 2.9 0.019 14.9 2.9 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF4834 PF16118.5 CDJ57908.1 - 0.07 14.1 3.2 0.1 13.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) THOC2_N PF16134.5 CDJ57908.1 - 0.15 10.7 3.8 0.19 10.3 3.8 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3357 PF11837.8 CDJ57908.1 - 1 9.8 4.5 2.1 8.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Tim54 PF11711.8 CDJ57908.1 - 1 8.0 6.3 1.3 7.8 6.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.12 CDJ57908.1 - 1.7 7.9 6.1 2.1 7.6 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.29 CDJ57909.1 - 0.00012 22.5 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_pp85 PF04637.12 CDJ57909.1 - 1.3 7.3 8.7 1.4 7.3 8.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CDJ57909.1 - 3.1 7.3 15.6 3.2 7.3 15.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DHHC PF01529.20 CDJ57910.1 - 0.0089 16.1 0.4 0.012 15.7 0.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Spt20 PF12090.8 CDJ57911.1 - 0.051 13.2 18.0 0.089 12.4 18.0 1.3 1 0 0 1 1 1 0 Spt20 family SAGA-Tad1 PF12767.7 CDJ57911.1 - 0.4 10.4 6.0 0.88 9.3 6.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2722 PF10846.8 CDJ57911.1 - 0.4 9.6 15.8 0.66 8.9 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ57911.1 - 0.41 10.4 4.4 0.76 9.5 4.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CCDC53 PF10152.9 CDJ57911.1 - 1.1 9.7 6.8 0.22 11.9 0.6 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Roughex PF06020.11 CDJ57911.1 - 2.1 7.4 7.4 3.6 6.6 7.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 CDJ57911.1 - 4 8.5 8.2 8.2 7.5 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) WD40 PF00400.32 CDJ57912.1 - 8e-06 26.5 2.3 0.0016 19.2 0.0 4.1 3 1 0 3 3 3 1 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ57912.1 - 0.0055 16.8 19.3 0.011 15.7 2.5 3.4 2 2 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ57912.1 - 0.0056 16.3 6.8 0.0056 16.3 6.8 3.8 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein T6SS-SciN PF12790.7 CDJ57912.1 - 0.037 13.7 0.7 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Spt20 PF12090.8 CDJ57912.1 - 1.6 8.3 21.3 0.74 9.4 1.2 2.9 2 1 1 3 3 3 0 Spt20 family Apt1 PF10351.9 CDJ57912.1 - 1.7 7.4 22.2 4e+02 -0.4 22.2 2.2 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF2681 PF10883.8 CDJ57912.1 - 4.5 7.7 10.4 15 6.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4171 PF13775.6 CDJ57912.1 - 6.2 7.3 32.6 0.45 11.0 4.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4171) TFIIA PF03153.13 CDJ57913.1 - 0.0086 16.1 20.0 0.0086 16.1 20.0 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 CDJ57913.1 - 0.087 13.1 2.2 2.7 8.5 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat XRN_N PF03159.18 CDJ57913.1 - 0.54 9.6 7.4 0.12 11.8 3.6 1.8 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Mitofilin PF09731.9 CDJ57913.1 - 1.2 7.9 32.5 2.3 7.0 3.1 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SAPS PF04499.15 CDJ57913.1 - 7.2 5.3 10.4 36 3.0 0.0 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PP2C PF00481.21 CDJ57914.1 - 1.9e-06 27.7 0.0 7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C HABP4_PAI-RBP1 PF04774.15 CDJ57915.1 - 1.3e-11 45.3 9.1 1.3e-11 45.3 9.1 3.1 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family CEP44 PF15007.6 CDJ57916.1 - 3.4e-42 143.6 0.0 6.9e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Aquarius_N PF16399.5 CDJ57917.1 - 3.6e-167 557.8 0.0 1.1e-85 288.4 0.0 4.0 4 0 0 4 4 4 3 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CDJ57917.1 - 6.5e-22 78.6 15.2 6.5e-22 78.6 15.2 4.6 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CDJ57917.1 - 3.4e-11 43.1 0.0 0.00024 20.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDJ57917.1 - 2.8e-05 24.5 3.2 0.0012 19.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CDJ57917.1 - 0.0011 18.6 0.0 0.047 13.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 CDJ57917.1 - 0.0018 17.7 0.0 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 CDJ57917.1 - 0.0028 18.0 2.7 0.0057 16.9 0.1 3.1 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 CDJ57917.1 - 0.0076 16.3 0.0 0.0076 16.3 0.0 2.7 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CDJ57917.1 - 0.008 16.2 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDJ57917.1 - 0.023 14.6 2.2 0.058 13.3 0.2 2.7 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 CDJ57917.1 - 0.023 14.3 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 CDJ57917.1 - 0.13 12.7 0.0 0.68 10.4 0.0 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF5591 PF17884.1 CDJ57917.1 - 0.18 11.7 0.5 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5591) AAA_18 PF13238.6 CDJ57917.1 - 0.2 12.2 1.2 0.74 10.4 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 CDJ57917.1 - 0.24 11.9 0.0 0.24 11.9 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.6 CDJ57917.1 - 0.29 11.3 0.0 0.29 11.3 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CDJ57917.1 - 1.2 9.4 0.0 1.2 9.4 0.0 5.1 6 1 0 6 6 3 0 AAA domain Peptidase_C14 PF00656.22 CDJ57918.1 - 3.6e-47 161.4 0.0 3.6e-47 161.4 0.0 2.1 2 1 0 2 2 2 1 Caspase domain HBS1_N PF08938.10 CDJ57918.1 - 0.00082 19.6 0.2 0.002 18.4 0.2 1.7 1 0 0 1 1 1 1 HBS1 N-terminus CUE PF02845.16 CDJ57918.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 CUE domain DUF3464 PF11947.8 CDJ57919.1 - 0.072 12.8 0.1 0.072 12.8 0.1 7.7 6 1 0 6 6 6 0 Photosynthesis affected mutant 68 adh_short PF00106.25 CDJ57920.1 - 6.3e-43 146.5 6.2 2.2e-42 144.7 6.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ57920.1 - 3e-37 128.4 4.8 1.2e-36 126.4 4.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 CDJ57920.1 - 1.1e-34 118.9 0.1 1.4e-16 60.8 0.0 2.5 2 0 0 2 2 2 2 SCP-2 sterol transfer family KR PF08659.10 CDJ57920.1 - 4.7e-15 56.0 2.0 9.1e-15 55.0 2.0 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 CDJ57920.1 - 0.0012 19.2 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal DUF4834 PF16118.5 CDJ57920.1 - 4.8 8.2 6.3 0.84 10.6 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RNase_H2_suC PF08615.11 CDJ57920.1 - 5.4 7.2 9.0 37 4.5 9.0 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Caldesmon PF02029.15 CDJ57921.1 - 0.27 10.0 62.1 0.33 9.7 62.1 1.0 1 0 0 1 1 1 0 Caldesmon RAP1 PF07218.11 CDJ57921.1 - 1.5 7.0 16.1 1.9 6.7 16.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RskA PF10099.9 CDJ57922.1 - 0.00021 21.6 0.3 0.00021 21.6 0.3 4.1 2 2 1 3 3 3 1 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ57922.1 - 0.42 10.1 18.9 0.76 9.3 18.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ57922.1 - 1.5 7.0 31.7 2.1 6.5 31.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hist_deacetyl PF00850.19 CDJ57922.1 - 3.5 7.0 15.6 14 5.0 15.6 2.2 1 1 0 1 1 1 0 Histone deacetylase domain SOBP PF15279.6 CDJ57922.1 - 8.6 6.9 27.0 1.3 9.6 21.1 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein KASH PF10541.9 CDJ57924.1 - 0.17 12.2 1.4 0.4 11.0 1.4 1.6 1 0 0 1 1 1 0 Nuclear envelope localisation domain RAP PF08373.10 CDJ57927.1 - 1.9e-12 47.1 0.1 3.2e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 RAP domain PAPA-1 PF04795.12 CDJ57927.1 - 0.0043 17.8 1.7 1.3 9.8 0.1 2.6 2 0 0 2 2 2 2 PAPA-1-like conserved region NifU PF01106.17 CDJ57928.1 - 4.2e-11 42.8 0.1 8.9e-08 32.2 0.1 2.6 2 1 0 2 2 2 2 NifU-like domain SR-25 PF10500.9 CDJ57929.1 - 0.00097 18.8 33.7 0.00097 18.8 33.7 6.3 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.13 CDJ57929.1 - 0.0014 17.8 6.9 0.0014 17.8 6.9 3.8 4 0 0 4 4 4 2 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CDJ57929.1 - 0.0014 18.7 26.8 0.0014 18.7 26.8 4.6 3 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 CDJ57929.1 - 0.002 16.8 11.9 0.002 16.8 11.9 3.2 3 0 0 3 3 3 2 Utp14 protein DUF2722 PF10846.8 CDJ57929.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 4.7 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ57929.1 - 0.0065 17.1 1.4 0.0065 17.1 1.4 8.3 5 2 1 6 6 6 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.19 CDJ57929.1 - 0.0081 16.7 6.3 0.0081 16.7 6.3 10.5 9 1 1 10 10 10 2 60s Acidic ribosomal protein BUD22 PF09073.10 CDJ57929.1 - 2.8 7.2 58.1 0.56 9.5 15.0 3.9 4 0 0 4 4 4 0 BUD22 GAGA_bind PF06217.12 CDJ57929.1 - 3.2 8.0 36.5 3.7 7.7 7.7 3.5 3 0 0 3 3 3 0 GAGA binding protein-like family Proteasome PF00227.26 CDJ57930.1 - 1.1e-45 155.5 0.1 1.2e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3834 PF12916.7 CDJ57930.1 - 0.088 12.0 0.1 2.9 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3834) zf-C2H2_jaz PF12171.8 CDJ57932.1 - 6.7e-05 23.1 1.4 0.00014 22.0 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDJ57932.1 - 0.00012 22.3 1.8 0.00022 21.5 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CDJ57932.1 - 0.26 11.1 0.9 0.61 9.9 0.9 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF3381 PF11861.8 CDJ57932.1 - 2.1 8.1 9.2 0.13 12.0 0.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3381) RskA PF10099.9 CDJ57933.1 - 7.9e-06 26.3 2.2 7.9e-06 26.3 2.2 14.8 2 2 11 13 13 13 4 Anti-sigma-K factor rskA NUC153 PF08159.12 CDJ57934.1 - 0.0004 20.1 1.2 0.00054 19.7 0.3 1.8 2 0 0 2 2 2 1 NUC153 domain Nop25 PF09805.9 CDJ57934.1 - 0.14 12.6 5.7 0.03 14.8 2.5 1.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spt20 PF12090.8 CDJ57936.1 - 0.0024 17.5 10.8 0.0024 17.5 10.8 9.1 5 2 2 8 8 8 3 Spt20 family Microtub_bd PF16796.5 CDJ57937.1 - 0.02 14.9 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 Microtubule binding Wtap PF17098.5 CDJ57938.1 - 9e-15 54.9 0.0 3e-11 43.5 0.0 3.2 2 1 1 3 3 3 2 WTAP/Mum2p family Phage_GP20 PF06810.11 CDJ57938.1 - 0.85 9.4 10.1 0.33 10.7 0.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Trypan_PARP PF05887.11 CDJ57938.1 - 5.6 6.9 19.4 1.1 9.2 15.4 1.9 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Spt20 PF12090.8 CDJ57939.1 - 0.0037 16.9 22.5 0.0037 16.9 22.5 6.4 5 3 0 5 5 5 1 Spt20 family Porin_4 PF13609.6 CDJ57939.1 - 0.013 15.3 2.1 0.013 15.3 2.1 1.9 2 0 0 2 2 2 0 Gram-negative porin RNA_pol_3_Rpc31 PF11705.8 CDJ57940.1 - 0.0029 17.9 24.5 0.0029 17.9 24.5 1.7 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 CDJ57940.1 - 0.012 13.7 32.3 0.86 7.6 30.4 2.1 2 0 0 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 CDJ57940.1 - 0.015 14.7 20.0 0.024 14.0 20.0 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CDJ57940.1 - 0.025 12.8 25.3 0.046 12.0 25.3 1.4 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 CDJ57940.1 - 0.062 13.4 23.4 0.016 15.4 19.6 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CDJ57940.1 - 0.099 11.6 2.3 0.17 10.8 2.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.13 CDJ57940.1 - 0.11 12.5 12.6 0.17 11.9 12.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIX1 PF08167.12 CDJ57940.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis RNA_pol_Rpc4 PF05132.14 CDJ57940.1 - 0.14 12.6 3.6 0.26 11.7 3.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 FdhE PF04216.12 CDJ57940.1 - 0.14 12.0 0.9 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation SDA1 PF05285.12 CDJ57940.1 - 0.17 11.3 24.4 0.3 10.5 24.4 1.4 1 0 0 1 1 1 0 SDA1 CBF PF03914.17 CDJ57940.1 - 0.21 11.6 3.2 0.23 11.5 1.6 1.9 2 0 0 2 2 1 0 CBF/Mak21 family CDC45 PF02724.14 CDJ57940.1 - 0.41 8.9 23.5 0.58 8.4 23.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.26 CDJ57940.1 - 0.6 10.6 11.2 1.7 9.1 4.7 2.5 2 0 0 2 2 2 0 Universal stress protein family PAXIP1_C PF15364.6 CDJ57940.1 - 0.65 10.3 16.8 1.8 8.9 16.8 1.7 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4820 PF16091.5 CDJ57940.1 - 0.69 9.2 7.4 1.2 8.5 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2151 PF10221.9 CDJ57940.1 - 0.76 8.3 9.5 1.1 7.8 9.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator PPP4R2 PF09184.11 CDJ57940.1 - 1 8.9 18.8 1.9 8.0 18.8 1.6 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 CDJ57940.1 - 1.1 9.1 13.2 1.6 8.5 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 CDJ57940.1 - 1.3 8.8 14.1 2.6 7.8 14.1 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 CDJ57940.1 - 1.7 8.0 13.9 2.6 7.4 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ57940.1 - 2.4 6.9 10.0 3.6 6.2 10.0 1.2 1 0 0 1 1 1 0 Presenilin HEAT_2 PF13646.6 CDJ57940.1 - 2.7 8.5 10.5 16 6.0 0.2 4.6 3 2 0 4 4 4 0 HEAT repeats NPR3 PF03666.13 CDJ57940.1 - 9.4 4.9 11.9 19 3.9 11.9 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM PF00493.23 CDJ57941.1 - 8.3e-80 267.1 0.0 1.3e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ57941.1 - 9.1e-10 38.8 1.2 7.7e-09 35.9 1.1 2.4 1 1 1 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ57941.1 - 2.5e-09 36.8 0.1 4.8e-06 26.1 0.0 3.0 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ57941.1 - 3.5e-07 30.1 0.0 2.3e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDJ57941.1 - 1.5e-05 25.1 0.0 4.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ57941.1 - 0.00034 20.5 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CDJ57941.1 - 0.027 14.9 3.6 0.03 14.7 0.1 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ57941.1 - 0.061 13.1 1.4 1 9.1 0.2 3.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CDJ57941.1 - 0.086 13.2 0.7 1.3 9.5 0.1 2.8 2 1 0 2 2 2 0 RNA helicase SieB PF14163.6 CDJ57941.1 - 0.09 12.3 1.1 0.65 9.5 0.6 2.5 1 1 1 2 2 2 0 Super-infection exclusion protein B AAA_22 PF13401.6 CDJ57941.1 - 0.36 11.1 7.6 3.6 7.9 0.0 3.8 3 1 0 4 4 4 0 AAA domain Med15 PF09606.10 CDJ57941.1 - 1.2 7.7 15.4 0.65 8.6 4.2 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_16 PF13191.6 CDJ57941.1 - 3 8.2 11.9 0.32 11.4 1.2 3.0 1 1 1 2 2 2 0 AAA ATPase domain DUF2681 PF10883.8 CDJ57941.1 - 3.3 8.2 18.8 5.3 7.5 3.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Mg_chelatase_C PF13335.6 CDJ57941.1 - 6.2 7.5 8.7 6.6 7.4 0.5 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal SPT2 PF08243.11 CDJ57942.1 - 3.9e-07 30.6 13.9 3.9e-07 30.6 13.9 6.5 6 2 0 6 6 6 1 SPT2 chromatin protein RskA PF10099.9 CDJ57942.1 - 0.00054 20.3 0.3 0.00054 20.3 0.3 6.1 2 2 4 6 6 6 2 Anti-sigma-K factor rskA Surface_antigen PF11054.8 CDJ57943.1 - 1.9e-18 67.0 11.1 1.3e-11 44.6 2.7 3.4 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen WD40 PF00400.32 CDJ57944.1 - 2e-13 50.6 6.8 0.022 15.6 0.0 5.2 4 2 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ57944.1 - 1.7e-06 28.2 0.0 0.46 10.8 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 CDJ57944.1 - 0.3 9.8 5.8 0.54 9.0 5.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sin_N PF04801.13 CDJ57944.1 - 0.46 9.7 19.0 0.2 10.8 2.0 2.1 2 0 0 2 2 2 0 Sin-like protein conserved region RAB3GAP2_N PF14655.6 CDJ57944.1 - 2.1 7.5 13.2 3 7.0 0.7 4.7 4 1 2 6 6 6 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EIIBC-GUT_N PF03612.14 CDJ57946.1 - 0.027 14.2 9.6 0.027 14.2 9.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0054 PF02130.17 CDJ57946.1 - 0.031 14.1 9.4 0.08 12.8 9.4 1.8 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 CPSF100_C PF13299.6 CDJ57946.1 - 0.034 14.3 9.5 0.033 14.4 9.5 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 CDJ57946.1 - 0.041 12.9 14.5 0.045 12.7 14.5 1.0 1 0 0 1 1 1 0 Paf1 DUF2514 PF10721.9 CDJ57946.1 - 0.06 13.4 3.6 0.065 13.3 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RPN2_C PF18004.1 CDJ57946.1 - 0.09 12.7 19.3 0.087 12.7 19.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 CDJ57946.1 - 0.091 11.0 11.8 0.092 11.0 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CDJ57946.1 - 0.094 12.1 7.5 0.09 12.2 7.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4604 PF15377.6 CDJ57946.1 - 0.18 12.2 21.5 0.19 12.1 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PcfK PF14058.6 CDJ57946.1 - 0.2 12.0 19.2 0.22 11.8 19.2 1.1 1 0 0 1 1 1 0 PcfK-like protein PGA_cap PF09587.10 CDJ57946.1 - 0.28 10.6 3.9 0.3 10.5 3.9 1.0 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Nse4_C PF08743.10 CDJ57946.1 - 0.32 11.3 7.7 3.1 8.1 7.7 2.0 1 1 0 1 1 1 0 Nse4 C-terminal TMEM214 PF10151.9 CDJ57946.1 - 0.33 9.3 18.1 0.39 9.1 18.1 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RR_TM4-6 PF06459.12 CDJ57946.1 - 0.34 10.7 16.1 0.35 10.6 16.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.6 CDJ57946.1 - 0.48 10.6 12.4 0.52 10.5 12.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein HSP90 PF00183.18 CDJ57946.1 - 0.52 9.1 16.8 0.48 9.3 16.8 1.0 1 0 0 1 1 1 0 Hsp90 protein NPR3 PF03666.13 CDJ57946.1 - 0.53 9.0 8.5 0.56 8.9 8.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Merozoite_SPAM PF07133.11 CDJ57946.1 - 0.56 10.2 23.3 0.68 9.9 23.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PPL5 PF18168.1 CDJ57946.1 - 0.57 9.4 10.7 0.61 9.3 10.7 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 CDJ57946.1 - 0.62 9.8 14.7 0.67 9.7 14.7 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ57946.1 - 0.62 8.8 6.8 0.62 8.8 6.8 1.0 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 CDJ57946.1 - 0.73 9.2 6.5 0.72 9.2 6.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Eapp_C PF10238.9 CDJ57946.1 - 0.81 9.7 9.5 0.88 9.6 9.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DDHD PF02862.17 CDJ57946.1 - 0.87 9.7 5.5 0.81 9.8 5.5 1.1 1 0 0 1 1 1 0 DDHD domain Peroxin-13_N PF04088.13 CDJ57946.1 - 0.98 9.7 6.2 1 9.6 6.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SspB PF04386.13 CDJ57946.1 - 1.1 9.1 9.8 1.3 8.8 9.8 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Vfa1 PF08432.10 CDJ57946.1 - 1.3 9.3 20.0 1.4 9.2 20.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AP-5_subunit_s1 PF15001.6 CDJ57946.1 - 1.3 9.0 7.3 1.7 8.6 7.3 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 FAM176 PF14851.6 CDJ57946.1 - 1.5 8.5 8.6 1.8 8.2 8.6 1.2 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.8 CDJ57946.1 - 1.6 7.5 19.5 1.8 7.4 19.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rrn6 PF10214.9 CDJ57946.1 - 1.7 7.1 6.9 1.8 7.0 6.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Folate_carrier PF01770.18 CDJ57946.1 - 1.7 7.3 7.8 1.8 7.2 7.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_pol_Rpc4 PF05132.14 CDJ57946.1 - 1.7 9.0 13.7 2.2 8.7 13.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM91_C PF14648.6 CDJ57946.1 - 1.8 7.3 6.5 2 7.2 6.5 1.0 1 0 0 1 1 1 0 FAM91 C-terminus AAA_11 PF13086.6 CDJ57946.1 - 2.1 8.0 9.6 2.1 8.0 9.6 1.1 1 0 0 1 1 1 0 AAA domain PTPRCAP PF15713.5 CDJ57946.1 - 2.4 8.4 14.2 2.8 8.2 14.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EOS1 PF12326.8 CDJ57946.1 - 2.7 7.9 5.6 2.7 7.9 5.6 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF913 PF06025.12 CDJ57946.1 - 3.1 6.7 6.5 3.1 6.7 6.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sec62 PF03839.16 CDJ57946.1 - 3.4 7.1 14.4 4 6.9 14.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Coilin_N PF15862.5 CDJ57946.1 - 3.7 7.3 19.6 6 6.7 19.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF2828 PF11443.8 CDJ57946.1 - 4.1 5.4 13.5 4.2 5.3 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Cellulose_synt PF03552.14 CDJ57946.1 - 4.1 5.8 7.5 4.5 5.6 7.5 1.0 1 0 0 1 1 1 0 Cellulose synthase TFB6 PF17110.5 CDJ57946.1 - 5.1 6.8 9.0 5.5 6.7 9.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CLN3 PF02487.17 CDJ57946.1 - 5.9 5.8 6.2 5.7 5.9 6.2 1.0 1 0 0 1 1 1 0 CLN3 protein CENP-N PF05238.13 CDJ57946.1 - 6.5 5.9 11.3 6.7 5.9 11.3 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Protocadherin PF08374.11 CDJ57946.1 - 10 6.1 14.0 13 5.7 14.0 1.2 1 0 0 1 1 1 0 Protocadherin E_Pc_C PF06752.12 CDJ57947.1 - 0.0041 17.3 9.3 0.0041 17.3 9.3 8.1 5 3 1 6 6 6 1 Enhancer of Polycomb C-terminus UPF0489 PF12640.7 CDJ57947.1 - 9.2 6.5 9.0 1.4 9.1 2.8 2.4 2 0 0 2 2 2 0 UPF0489 domain Romo1 PF10247.9 CDJ57948.1 - 2.7e-15 56.5 15.2 3.9e-15 56.0 15.2 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Surface_antigen PF11054.8 CDJ57949.1 - 6.6e-68 229.0 0.7 9.3e-68 228.5 0.7 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ57950.1 - 5e-75 252.3 2.9 5.8e-75 252.1 2.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen UPF0182 PF03699.13 CDJ57950.1 - 0.014 13.6 0.1 0.018 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Surface_antigen PF11054.8 CDJ57951.1 - 5.1e-72 242.5 4.9 9.7e-72 241.5 4.9 1.4 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen HsbA PF12296.8 CDJ57951.1 - 0.14 12.6 1.1 0.48 10.9 0.1 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Surface_antigen PF11054.8 CDJ57952.1 - 2e-72 243.8 2.1 2.5e-72 243.5 2.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ57953.1 - 1.6e-82 276.9 0.9 1.8e-82 276.7 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Phage_TTP_13 PF16463.5 CDJ57953.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.5 1 1 0 1 1 1 1 Phage tail tube protein family GCD14 PF08704.10 CDJ57954.1 - 2e-65 220.9 0.0 3.7e-41 141.4 0.0 2.2 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDJ57954.1 - 4.2e-06 26.6 0.0 4.2e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ57954.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDJ57954.1 - 0.08 13.7 0.0 0.32 11.7 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ57954.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Surface_antigen PF11054.8 CDJ57955.1 - 1.5e-74 250.7 0.2 1.8e-74 250.5 0.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Sulf_transp PF04143.14 CDJ57956.1 - 0.043 13.4 1.8 0.061 12.9 1.8 1.3 1 0 0 1 1 1 0 Sulphur transport DUF4342 PF14242.6 CDJ57956.1 - 4.1 7.5 7.9 14 5.7 2.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF898 PF05987.13 CDJ57956.1 - 4.3 6.3 7.6 1.5 7.8 4.7 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2298 PF10060.9 CDJ57956.1 - 5.5 5.6 8.3 7.5 5.1 8.3 1.2 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Trp_oprn_chp PF09534.10 CDJ57956.1 - 6.6 6.5 46.3 2 8.2 17.1 2.3 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BAF1_ABF1 PF04684.13 CDJ57957.1 - 0.029 13.4 13.6 0.046 12.8 13.6 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM60A PF15396.6 CDJ57957.1 - 0.048 13.7 8.5 0.063 13.3 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Senescence_reg PF04520.13 CDJ57957.1 - 0.072 13.9 13.8 0.097 13.5 13.8 1.3 1 0 0 1 1 1 0 Senescence regulator RIFIN PF02009.16 CDJ57957.1 - 0.11 12.4 7.6 0.13 12.1 7.6 1.1 1 0 0 1 1 1 0 Rifin Hid1 PF12722.7 CDJ57957.1 - 0.54 8.3 15.3 0.67 8.0 15.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Podoplanin PF05808.11 CDJ57957.1 - 0.96 9.5 6.2 1.7 8.8 6.2 1.3 1 0 0 1 1 1 0 Podoplanin Shadoo PF14999.6 CDJ57957.1 - 0.97 9.5 11.6 0.76 9.9 10.4 1.5 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Ndc1_Nup PF09531.10 CDJ57957.1 - 2.2 6.9 20.0 2.5 6.7 20.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Miga PF10265.9 CDJ57957.1 - 7 5.5 13.4 8.7 5.2 13.4 1.1 1 0 0 1 1 1 0 Mitoguardin zf-CCCH PF00642.24 CDJ57958.1 - 7.2e-09 35.3 3.7 1.4e-08 34.4 1.8 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ57958.1 - 1.2e-06 28.4 3.0 1.2e-06 28.4 3.0 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CDJ57958.1 - 4.5e-06 26.3 2.2 1e-05 25.2 1.0 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 CDJ57958.1 - 0.001 19.8 1.4 0.001 19.8 1.4 3.1 1 1 1 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 CDJ57958.1 - 0.0017 18.7 4.7 0.0019 18.6 1.5 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Suf PF05843.14 CDJ57958.1 - 0.087 12.8 5.8 0.11 12.4 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCCH_3 PF15663.5 CDJ57958.1 - 0.2 11.9 8.7 0.83 9.9 5.8 2.4 2 1 0 2 2 2 0 Zinc-finger containing family BBS2_N PF14781.6 CDJ57958.1 - 1 9.3 9.9 1.6 8.7 1.1 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal KDGP_aldolase PF07071.11 CDJ57958.1 - 1.2 8.9 4.5 2.6 7.8 4.5 1.5 1 1 0 1 1 1 0 KDGP aldolase Presenilin PF01080.17 CDJ57958.1 - 1.8 7.3 6.4 2.6 6.7 6.4 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CDJ57959.1 - 0.0015 18.2 40.1 0.0015 18.2 40.1 12.1 3 3 8 11 11 11 2 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ57959.1 - 0.0061 16.8 11.0 0.0061 16.8 11.0 18.7 10 5 5 15 15 15 1 Domain of unknown function (DUF755) Spore_YhcN_YlaJ PF09580.10 CDJ57959.1 - 0.0064 16.6 0.0 0.0064 16.6 0.0 11.0 3 3 2 5 5 5 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2722 PF10846.8 CDJ57960.1 - 0.0033 16.4 7.2 0.0033 16.4 7.2 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) MAT1 PF06391.13 CDJ57960.1 - 1.1 9.0 46.5 0.21 11.4 17.1 3.4 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 Peptidase_M14 PF00246.24 CDJ57961.1 - 1.4e-08 34.9 0.0 0.006 16.4 0.0 3.0 1 1 1 2 2 2 2 Zinc carboxypeptidase SR-25 PF10500.9 CDJ57961.1 - 0.0012 18.6 4.0 0.0012 18.6 4.0 4.1 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ57961.1 - 0.23 10.3 0.0 0.23 10.3 0.0 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2722) MPM1 PF17234.2 CDJ57961.1 - 0.36 11.1 0.0 0.36 11.1 0.0 4.8 5 0 0 5 5 5 0 Mitochondrial peculiar membrane protein 1 Cdh1_DBD_1 PF18196.1 CDJ57961.1 - 9.4 6.6 7.3 3.1 8.1 1.3 3.1 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Rrn6 PF10214.9 CDJ57962.1 - 0.023 13.2 9.2 0.026 13.0 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3915 PF13054.6 CDJ57962.1 - 1.7 8.6 7.6 2.7 8.0 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Abhydro_lipase PF04083.16 CDJ57964.1 - 3.5e-07 29.7 0.0 1.2e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDJ57964.1 - 1.5e-05 24.8 3.5 0.045 13.4 0.0 3.7 5 0 0 5 5 5 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ57964.1 - 0.013 16.1 7.0 1.9 9.0 4.0 3.2 3 1 0 3 3 3 0 Alpha/beta hydrolase family Rab15_effector PF15208.6 CDJ57964.1 - 0.074 12.3 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Rab15 effector Hydrolase_4 PF12146.8 CDJ57964.1 - 0.15 11.3 4.9 4 6.6 0.0 3.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PLAC8 PF04749.17 CDJ57964.1 - 0.28 12.2 0.1 0.28 12.2 0.1 3.8 5 0 0 5 5 5 0 PLAC8 family DSBA PF01323.20 CDJ57965.1 - 5.1 6.8 7.1 6.9 6.4 0.0 2.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF4231 PF14015.6 CDJ57966.1 - 4.4 7.8 5.6 1.1e+02 3.4 5.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) dCMP_cyt_deam_2 PF08211.12 CDJ57968.1 - 5.1e-06 26.7 6.0 8.2e-06 26.1 6.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Apc15p PF05841.11 CDJ57968.1 - 0.025 15.4 12.2 0.028 15.2 12.2 1.0 1 0 0 1 1 1 0 Apc15p protein Tfb4 PF03850.14 CDJ57968.1 - 0.077 12.5 4.4 0.09 12.3 4.4 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Sin_N PF04801.13 CDJ57968.1 - 0.29 10.3 16.7 0.33 10.1 16.7 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF853 PF05872.12 CDJ57968.1 - 0.47 9.0 6.1 0.5 8.9 6.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) EPL1 PF10513.9 CDJ57968.1 - 0.86 10.0 11.1 1 9.7 11.1 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Connexin PF00029.19 CDJ57968.1 - 1.2 8.8 6.3 1.2 8.8 6.3 1.1 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 CDJ57968.1 - 1.3 8.5 6.3 1.4 8.4 6.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Spc7_N PF15402.6 CDJ57968.1 - 1.3 7.2 9.2 1.4 7.1 9.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FAM176 PF14851.6 CDJ57968.1 - 1.4 8.6 5.0 1.6 8.3 5.0 1.1 1 0 0 1 1 1 0 FAM176 family Gastrin PF00918.17 CDJ57968.1 - 1.5 9.8 8.6 1.6 9.7 8.6 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Peptidase_C58 PF03543.14 CDJ57968.1 - 1.5 8.5 15.2 1.7 8.3 15.2 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Peptidase_S15 PF02129.18 CDJ57968.1 - 2 7.9 9.5 2.4 7.7 9.5 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) EIIBC-GUT_N PF03612.14 CDJ57968.1 - 2.2 8.0 7.9 2.5 7.8 7.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 CDJ57968.1 - 2.2 8.2 26.6 2.3 8.1 26.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 CDJ57968.1 - 2.5 8.2 8.1 2.5 8.2 8.1 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.12 CDJ57968.1 - 2.7 7.3 14.6 3.2 7.1 14.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 CDJ57968.1 - 3 8.0 9.3 3.5 7.8 9.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CDJ57968.1 - 3.1 8.4 18.9 3.7 8.2 18.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CDJ57968.1 - 4.1 6.1 11.9 4.4 6.0 11.9 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ57968.1 - 4.4 6.0 7.0 4.7 5.9 7.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ57968.1 - 6.5 4.9 18.6 7.3 4.7 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ57968.1 - 7.1 5.7 5.6 8.5 5.5 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ57968.1 - 7.4 6.6 6.8 8.1 6.4 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CDJ57968.1 - 9.7 4.7 9.9 9.7 4.7 9.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLN3 PF02487.17 CDJ57968.1 - 9.7 5.1 8.6 9.9 5.1 8.6 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2722 PF10846.8 CDJ57969.1 - 0.0046 16.0 2.4 0.0046 16.0 2.4 6.3 2 1 3 6 6 6 2 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.19 CDJ57969.1 - 0.021 15.4 9.8 0.021 15.4 9.8 8.4 7 2 1 9 9 9 0 60s Acidic ribosomal protein ALMT PF11744.8 CDJ57970.1 - 0.85 8.4 36.1 0.054 12.3 15.6 2.9 3 0 0 3 3 3 0 Aluminium activated malate transporter DUF4770 PF15994.5 CDJ57970.1 - 1.4 9.1 28.5 1.4 9.1 7.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) Zip PF02535.22 CDJ57970.1 - 3.6 6.7 19.5 2.2 7.4 6.7 2.9 3 0 0 3 3 3 0 ZIP Zinc transporter Suf PF05843.14 CDJ57970.1 - 3.7 7.4 43.0 1.9 8.4 14.7 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF3597 PF12200.8 CDJ57971.1 - 0.42 11.2 6.3 0.79 10.3 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Herpes_capsid PF06112.11 CDJ57971.1 - 0.78 9.8 5.8 0.95 9.5 5.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MCR_alpha PF02249.17 CDJ57971.1 - 1.2 9.6 5.5 1.8 9.0 5.4 1.5 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain ECH_2 PF16113.5 CDJ57973.1 - 4e-18 66.0 4.9 2e-08 34.2 0.9 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Spt20 PF12090.8 CDJ57974.1 - 0.006 16.2 6.0 0.006 16.2 6.0 3.7 4 0 0 4 4 4 2 Spt20 family EPL1 PF10513.9 CDJ57974.1 - 0.53 10.7 15.7 3.7 7.9 2.3 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like dsDNA_bind PF01984.20 CDJ57974.1 - 9.4 6.6 33.4 6.4 7.1 5.9 3.7 3 0 0 3 3 3 0 Double-stranded DNA-binding domain FHA PF00498.26 CDJ57975.1 - 4.9e-06 26.8 13.2 5.7e-05 23.4 13.2 2.2 1 1 0 1 1 1 1 FHA domain HNH PF01844.23 CDJ57975.1 - 0.043 14.0 0.5 0.086 13.0 0.5 1.5 1 0 0 1 1 1 0 HNH endonuclease FAM60A PF15396.6 CDJ57975.1 - 4.6 7.2 15.5 0.38 10.7 7.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A LMBR1 PF04791.16 CDJ57975.1 - 7.3 5.4 5.4 12 4.7 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Yop-YscD_cpl PF16697.5 CDJ57975.1 - 9.2 6.7 14.5 0.15 12.4 2.3 3.3 3 0 0 3 3 3 0 Inner membrane component of T3SS, cytoplasmic domain DUF4746 PF15928.5 CDJ57976.1 - 1 8.7 7.1 3.2 7.1 7.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) WD40 PF00400.32 CDJ57977.1 - 6.2e-05 23.7 0.1 6.2e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat LptF_LptG PF03739.14 CDJ57980.1 - 0.0044 15.9 0.1 0.0061 15.4 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF3169 PF11368.8 CDJ57980.1 - 0.0083 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF4064 PF13273.6 CDJ57980.1 - 0.019 15.2 0.9 0.019 15.2 0.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Dpy19 PF10034.9 CDJ57980.1 - 0.052 11.7 4.6 0.022 13.0 2.3 1.4 1 1 0 1 1 1 0 Q-cell neuroblast polarisation TFIIA PF03153.13 CDJ57980.1 - 0.066 13.2 36.8 0.084 12.9 36.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 CDJ57980.1 - 0.12 11.4 37.5 0.15 11.1 37.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2232 PF09991.9 CDJ57980.1 - 0.15 11.2 3.6 0.21 10.7 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) GTA_holin_3TM PF11351.8 CDJ57980.1 - 0.52 10.9 3.4 0.81 10.2 3.4 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Peptidase_S64 PF08192.11 CDJ57980.1 - 2.3 6.6 50.8 3.3 6.1 50.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 OAD_gamma PF04277.13 CDJ57980.1 - 2.5 8.7 6.2 0.35 11.5 0.4 2.4 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Activator_LAG-3 PF11498.8 CDJ57981.1 - 0.0003 19.9 29.9 0.0003 19.9 29.9 8.6 3 2 7 10 10 10 1 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ57982.1 - 0.00075 19.2 18.8 0.00075 19.2 18.8 8.5 7 2 2 9 9 9 4 Nuclear RNA-splicing-associated protein PRP1_N PF06424.12 CDJ57984.1 - 0.0065 16.9 2.6 0.0065 16.9 2.6 3.0 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal XRN_M PF17846.1 CDJ57984.1 - 0.91 8.4 10.8 0.14 11.1 6.4 1.7 2 0 0 2 2 2 0 Xrn1 helical domain hDGE_amylase PF14701.6 CDJ57984.1 - 3 6.8 11.9 6.8 5.7 11.9 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CAF1 PF04857.20 CDJ57984.1 - 7.3 5.7 13.8 7.3 5.6 9.0 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease RskA PF10099.9 CDJ57985.1 - 0.0034 17.7 2.9 0.0034 17.7 2.9 9.3 2 1 3 6 6 6 2 Anti-sigma-K factor rskA Arf PF00025.21 CDJ57986.1 - 3.4e-40 137.3 0.0 3.8e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDJ57986.1 - 1.1e-08 34.6 0.2 4.5e-06 26.1 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDJ57986.1 - 3.7e-08 33.0 0.0 4.3e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ57986.1 - 8.1e-07 29.1 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ57986.1 - 9.5e-07 29.1 0.0 2.4e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ57986.1 - 0.00012 21.8 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDJ57986.1 - 0.00046 19.6 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CDJ57986.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CDJ57986.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Cys_rich_CPXG PF14255.6 CDJ57987.1 - 0.11 12.4 2.3 0.42 10.5 1.4 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG DNA_ligase_A_N PF04675.14 CDJ57987.1 - 0.19 12.1 1.7 0.36 11.1 0.0 2.3 2 1 0 2 2 2 0 DNA ligase N terminus Caldesmon PF02029.15 CDJ57988.1 - 0.00024 20.0 27.8 0.00031 19.7 27.8 1.1 1 0 0 1 1 1 1 Caldesmon Connexin PF00029.19 CDJ57988.1 - 0.0026 17.5 23.4 0.08 12.7 2.1 2.1 2 0 0 2 2 2 2 Connexin DUF4746 PF15928.5 CDJ57988.1 - 0.0091 15.5 30.0 0.043 13.2 14.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.13 CDJ57988.1 - 0.0095 16.2 20.0 0.012 15.9 20.0 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated DUF3682 PF12446.8 CDJ57988.1 - 0.02 15.4 17.1 0.02 15.4 17.1 4.6 2 2 1 3 3 2 0 Protein of unknown function (DUF3682) FAM76 PF16046.5 CDJ57988.1 - 0.03 13.7 26.5 0.12 11.7 14.6 2.0 2 0 0 2 2 2 0 FAM76 protein TCP PF03634.13 CDJ57988.1 - 0.033 14.7 25.7 0.1 13.2 13.3 2.2 2 0 0 2 2 2 0 TCP family transcription factor PAT1 PF09770.9 CDJ57988.1 - 0.046 12.0 44.0 0.062 11.6 44.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3807 PF12720.7 CDJ57988.1 - 0.052 13.8 39.3 0.27 11.5 21.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 CDJ57988.1 - 0.14 12.0 39.4 0.065 13.0 17.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Apc15p PF05841.11 CDJ57988.1 - 0.15 12.9 31.9 1.7 9.4 18.1 2.3 2 0 0 2 2 2 0 Apc15p protein PTPRCAP PF15713.5 CDJ57988.1 - 0.21 11.8 37.1 0.89 9.8 9.6 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AF-4 PF05110.13 CDJ57988.1 - 0.24 9.5 38.8 0.29 9.2 38.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Vfa1 PF08432.10 CDJ57988.1 - 0.27 11.6 36.0 0.4 11.0 7.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Dapper PF15268.6 CDJ57988.1 - 0.31 9.9 30.9 0.35 9.7 30.9 1.1 1 0 0 1 1 1 0 Dapper BAF1_ABF1 PF04684.13 CDJ57988.1 - 0.32 10.0 27.5 0.46 9.5 27.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.12 CDJ57988.1 - 0.32 9.9 33.1 0.087 11.8 19.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EFTUD2 PF16004.5 CDJ57988.1 - 0.33 11.5 32.9 1.1 9.8 5.9 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF3340 PF11818.8 CDJ57988.1 - 0.33 11.1 30.9 0.38 10.9 10.8 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Isy1 PF06246.12 CDJ57988.1 - 0.49 9.9 30.2 0.75 9.3 16.4 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Dynamin_N PF00350.23 CDJ57988.1 - 0.71 9.9 12.3 0.5 10.4 4.8 2.1 2 0 0 2 2 2 0 Dynamin family DUF4551 PF15087.6 CDJ57988.1 - 0.74 8.6 22.6 0.9 8.3 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4820 PF16091.5 CDJ57988.1 - 1.1 8.6 23.2 0.92 8.8 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4666 PF15697.5 CDJ57988.1 - 1.1 9.9 23.4 0.34 11.6 10.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Membralin PF09746.9 CDJ57988.1 - 1.1 8.2 17.2 0.45 9.5 8.5 2.2 2 0 0 2 2 2 0 Tumour-associated protein XAP5 PF04921.14 CDJ57988.1 - 1.2 9.0 29.7 3 7.6 15.5 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator TRAP_alpha PF03896.16 CDJ57988.1 - 1.4 8.0 20.7 0.075 12.2 6.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit NST1 PF13945.6 CDJ57988.1 - 1.7 8.7 39.9 2 8.5 23.8 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator RPA43_OB PF17875.1 CDJ57988.1 - 1.7 9.2 21.7 6.5 7.4 3.0 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I NPR3 PF03666.13 CDJ57988.1 - 2 7.1 29.3 1.7 7.4 3.7 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 TT_ORF1 PF02956.14 CDJ57988.1 - 2.7 6.6 16.4 0.27 9.9 8.2 2.0 2 0 0 2 2 2 0 TT viral orf 1 FAM176 PF14851.6 CDJ57988.1 - 4.2 7.0 25.3 2.5 7.8 13.1 2.2 2 0 0 2 2 2 0 FAM176 family ALMT PF11744.8 CDJ57988.1 - 4.3 6.1 23.3 1.7 7.4 12.5 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF853 PF05872.12 CDJ57988.1 - 4.3 5.8 20.5 0.23 10.0 7.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Striatin PF08232.12 CDJ57988.1 - 4.3 7.9 36.8 6.8 7.3 20.3 2.2 2 0 0 2 2 2 0 Striatin family DUF702 PF05142.12 CDJ57988.1 - 5.2 7.5 28.9 6.1 7.3 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) FAM60A PF15396.6 CDJ57988.1 - 5.3 7.0 28.0 6.1 6.8 3.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A RP-C_C PF11800.8 CDJ57988.1 - 5.9 6.9 29.8 7.8 6.5 5.7 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF3449 PF11931.8 CDJ57988.1 - 5.9 6.6 26.7 0.47 10.2 12.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF4471 PF14740.6 CDJ57988.1 - 6.4 5.9 21.7 4.2 6.5 12.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) PPL5 PF18168.1 CDJ57988.1 - 6.8 5.9 25.7 0.42 9.8 11.3 2.1 2 0 0 2 2 2 0 Prim-pol family 5 CLN3 PF02487.17 CDJ57988.1 - 7.2 5.5 25.5 3.4 6.6 14.8 2.0 2 0 0 2 2 2 0 CLN3 protein YABBY PF04690.13 CDJ57988.1 - 7.5 7.1 24.7 7 7.2 14.4 2.2 2 0 0 2 2 2 0 YABBY protein DUF1764 PF08576.10 CDJ57988.1 - 7.5 7.5 36.0 0.84 10.6 5.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) LicD PF04991.13 CDJ57988.1 - 7.9 6.5 8.6 3.5 7.7 2.5 2.1 2 0 0 2 2 2 0 LicD family ATP11 PF06644.11 CDJ57988.1 - 8 6.2 39.2 3.1 7.5 21.8 2.1 2 0 0 2 2 2 0 ATP11 protein CRT10 PF08728.10 CDJ57988.1 - 9.2 4.3 11.6 12 3.9 11.6 1.1 1 0 0 1 1 1 0 CRT10 Sec62 PF03839.16 CDJ57988.1 - 9.4 5.7 29.9 6.9 6.1 5.9 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 RPOL_N PF14700.6 CDJ57988.1 - 9.6 5.5 35.2 7.8 5.8 6.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal WASH-7_C PF14746.6 CDJ57988.1 - 9.7 5.8 25.9 0.24 11.1 10.7 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal CENP-N PF05238.13 CDJ57988.1 - 9.7 5.4 20.4 3.1 7.0 8.6 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Methyltransf_15 PF09445.10 CDJ57989.1 - 3.8e-10 39.6 0.2 4.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Dehydrin PF00257.19 CDJ57989.1 - 0.00011 22.8 2.6 0.00011 22.8 2.6 6.2 4 2 2 6 6 5 2 Dehydrin TFIIA PF03153.13 CDJ57989.1 - 0.0012 18.9 51.6 0.0025 17.9 10.6 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ57989.1 - 0.0017 18.7 0.9 0.0017 18.7 0.9 5.2 3 2 1 4 4 3 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ57989.1 - 0.0019 17.9 56.2 0.042 13.5 29.3 2.5 2 0 0 2 2 2 2 Spt20 family YL1 PF05764.13 CDJ57989.1 - 0.0048 17.1 1.3 0.0048 17.1 1.3 2.9 3 0 0 3 3 2 1 YL1 nuclear protein DDHD PF02862.17 CDJ57989.1 - 0.19 11.9 21.6 2.2 8.4 1.4 3.3 3 0 0 3 3 3 0 DDHD domain SR-25 PF10500.9 CDJ57989.1 - 0.24 11.0 73.9 0.043 13.4 2.9 4.4 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 CDJ57989.1 - 0.24 11.9 20.7 1.1 9.7 4.4 2.2 2 0 0 2 2 2 0 AAA domain MecA PF05389.12 CDJ57989.1 - 0.74 9.4 11.9 1.8 8.2 3.2 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) SET PF00856.28 CDJ57989.1 - 0.91 9.9 5.3 7.4 6.9 0.1 3.0 3 0 0 3 3 3 0 SET domain Anoctamin PF04547.12 CDJ57989.1 - 1.6 7.5 5.1 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel EPL1 PF10513.9 CDJ57989.1 - 5.6 7.3 24.1 0.068 13.5 5.0 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 CDJ57989.1 - 5.9 5.7 63.1 1.3 7.9 29.1 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SpoIIP PF07454.11 CDJ57989.1 - 8.9 5.7 20.3 2.6 7.4 9.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RskA PF10099.9 CDJ57990.1 - 0.019 15.3 10.7 0.019 15.3 10.7 4.0 1 1 2 4 4 4 0 Anti-sigma-K factor rskA Shadoo PF14999.6 CDJ57990.1 - 0.24 11.5 5.8 0.39 10.8 5.8 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PAP2 PF01569.21 CDJ57991.1 - 0.027 14.3 0.7 12 5.7 0.2 3.3 2 1 0 2 2 2 0 PAP2 superfamily Pentapeptide_4 PF13599.6 CDJ57991.1 - 0.5 10.6 13.0 53 4.1 0.7 3.2 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Ribosomal_L1 PF00687.21 CDJ57992.1 - 1.9e-29 102.9 2.4 2.3e-29 102.6 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S24e PF01282.19 CDJ57993.1 - 2.5e-25 88.2 0.0 4.2e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e P120R PF08062.11 CDJ57993.1 - 0.13 12.6 9.9 1.5 9.2 0.1 2.8 2 0 0 2 2 2 0 P120R (NUC006) repeat WD40 PF00400.32 CDJ57994.1 - 1.3e-07 32.2 13.5 3.2e-05 24.6 0.1 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Macoilin PF09726.9 CDJ57994.1 - 0.0093 14.6 12.8 0.0037 15.9 10.4 1.3 1 1 0 1 1 1 1 Macoilin family Ribosomal_60s PF00428.19 CDJ57994.1 - 6.5 7.4 22.1 0.67 10.6 12.5 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_M75 PF09375.10 CDJ57995.1 - 0.064 12.7 0.1 9.7 5.6 0.0 2.5 3 0 0 3 3 3 0 Imelysin AAA_lid_7 PF17867.1 CDJ57995.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Midasin AAA lid domain AIM3 PF17096.5 CDJ57996.1 - 0.001 20.0 2.1 0.0032 18.4 2.1 1.9 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 3 Ferritin PF00210.24 CDJ57997.1 - 0.15 12.0 2.6 0.58 10.1 0.2 2.4 1 1 0 2 2 2 0 Ferritin-like domain CCDC-167 PF15188.6 CDJ57997.1 - 0.32 11.3 1.8 0.77 10.1 1.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Sec8_exocyst PF04048.14 CDJ57997.1 - 6 6.8 7.4 2.1 8.2 0.3 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Pex14_N PF04695.13 CDJ58004.1 - 0.012 16.3 27.4 0.012 16.3 27.4 12.0 6 2 4 10 10 10 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAP1 PF07218.11 CDJ58005.1 - 0.001 17.5 3.3 0.001 17.5 3.3 2.5 3 0 0 3 3 3 1 Rhoptry-associated protein 1 (RAP-1) VIR_N PF15912.5 CDJ58005.1 - 2.5 7.7 18.0 0.1 12.2 8.9 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Caldesmon PF02029.15 CDJ58005.1 - 4 6.1 29.4 6.7 5.3 29.4 1.4 1 0 0 1 1 1 0 Caldesmon DUF4746 PF15928.5 CDJ58005.1 - 7.2 5.9 18.7 0.13 11.7 10.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SR-25 PF10500.9 CDJ58006.1 - 6.2e-05 22.7 7.7 6.2e-05 22.7 7.7 3.6 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ58006.1 - 0.0082 15.8 11.2 0.0082 15.8 11.2 5.2 3 1 1 4 4 4 1 Spt20 family CCSAP PF15748.5 CDJ58006.1 - 1.1 9.4 39.2 0.98 9.5 16.0 3.2 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated TetR_C_24 PF17932.1 CDJ58008.1 - 0.24 11.7 7.6 0.22 11.8 6.9 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3323 PF11796.8 CDJ58008.1 - 3.3 7.5 10.2 4 7.3 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Secretin_N_2 PF07655.13 CDJ58009.1 - 0.094 13.3 17.3 0.35 11.4 17.3 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Chorion_2 PF03964.15 CDJ58009.1 - 0.41 11.5 14.3 1.9 9.3 7.8 2.5 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.8 CDJ58009.1 - 1.3 9.3 22.4 0.16 12.3 18.2 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain TFIIA PF03153.13 CDJ58012.1 - 0.0053 16.8 40.3 0.17 11.9 13.5 2.5 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ58012.1 - 0.0068 17.1 5.5 0.0068 17.1 5.5 4.5 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M50B PF13398.6 CDJ58014.1 - 3e-20 72.7 5.4 3.4e-20 72.5 5.4 1.0 1 0 0 1 1 1 1 Peptidase M50B-like PLU-1 PF08429.11 CDJ58015.1 - 8.4e-17 61.4 13.6 3e-11 43.1 0.0 9.2 7 3 0 7 7 7 4 PLU-1-like protein PHD PF00628.29 CDJ58015.1 - 0.3 11.0 3.2 1.6 8.7 3.2 2.3 1 1 0 1 1 1 0 PHD-finger Npa1 PF11707.8 CDJ58017.1 - 0.03 13.7 0.7 0.14 11.5 0.5 1.9 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal MA-Mit PF09245.10 CDJ58018.1 - 0.13 11.7 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Mycoplasma arthritidis-derived mitogen DUF4936 PF16290.5 CDJ58019.1 - 1.2 9.8 5.1 1.2 9.9 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4936) DUF4834 PF16118.5 CDJ58019.1 - 6.9 7.7 6.4 2.7e+02 2.6 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) zf-CCHC_2 PF13696.6 CDJ58020.1 - 8.7e-08 31.8 3.5 2e-07 30.7 3.5 1.7 1 0 0 1 1 1 1 Zinc knuckle SUIM_assoc PF16619.5 CDJ58020.1 - 5e-06 26.5 11.3 2 8.5 15.3 4.4 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 zf-CCHC PF00098.23 CDJ58020.1 - 0.0086 16.1 5.2 0.022 14.8 5.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-RING_UBOX PF13445.6 CDJ58020.1 - 0.04 14.0 6.2 0.12 12.5 6.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC_4 PF14392.6 CDJ58020.1 - 0.15 11.8 2.8 0.39 10.5 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L23 PF00276.20 CDJ58021.1 - 8.7e-15 54.9 1.5 8.7e-15 54.9 1.5 2.6 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CDJ58021.1 - 1.3e-05 25.3 12.9 1.3e-05 25.3 12.9 2.6 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Linker_histone PF00538.19 CDJ58021.1 - 0.037 14.4 6.0 0.71 10.3 0.5 2.5 2 0 0 2 2 2 0 linker histone H1 and H5 family Syntaxin-6_N PF09177.11 CDJ58022.1 - 5.4e-06 26.9 10.1 0.00012 22.5 8.7 2.7 1 1 1 2 2 2 1 Syntaxin 6, N-terminal Nup88 PF10168.9 CDJ58022.1 - 0.0039 15.1 3.5 0.0041 15.0 3.5 1.1 1 0 0 1 1 1 1 Nuclear pore component betaPIX_CC PF16523.5 CDJ58022.1 - 0.0098 15.7 1.5 0.32 10.8 0.0 2.6 2 1 0 2 2 2 1 betaPIX coiled coil DUF3675 PF12428.8 CDJ58022.1 - 0.018 15.6 1.8 0.034 14.7 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) V_ATPase_I PF01496.19 CDJ58022.1 - 0.05 11.5 2.8 0.057 11.3 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mem_trans PF03547.18 CDJ58022.1 - 0.055 11.9 0.8 0.072 11.5 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein zf-CpG_bind_C PF12269.8 CDJ58022.1 - 0.1 12.4 6.7 0.091 12.5 5.1 1.7 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Jnk-SapK_ap_N PF09744.9 CDJ58022.1 - 0.11 12.8 7.8 0.09 13.0 4.9 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 AATF-Che1 PF13339.6 CDJ58022.1 - 0.87 10.3 8.2 1.8 9.3 8.2 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 CDJ58022.1 - 1 8.8 6.4 1.4 8.4 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M61 PF05299.12 CDJ58022.1 - 1.8 9.0 4.6 21 5.6 4.4 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase NPV_P10 PF05531.12 CDJ58022.1 - 2.7 8.5 6.4 4.2 7.9 4.8 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SNARE PF05739.19 CDJ58022.1 - 4.6 7.3 7.1 3.3 7.8 3.0 2.6 2 1 0 2 2 2 0 SNARE domain Phage_GPO PF05929.11 CDJ58022.1 - 7 6.2 11.3 13 5.3 11.3 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PI3_PI4_kinase PF00454.27 CDJ58024.1 - 2.2e-30 106.3 1.2 2.2e-30 106.3 1.2 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDJ58024.1 - 1.2e-14 54.2 2.4 1.3e-08 34.4 0.1 2.7 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDJ58024.1 - 0.0031 17.4 0.0 0.0031 17.4 0.0 3.9 5 0 0 5 5 5 1 Phosphoinositide 3-kinase C2 Herpes_BLLF1 PF05109.13 CDJ58025.1 - 0.047 11.7 1.0 0.069 11.1 1.0 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Methyltr_RsmB-F PF01189.17 CDJ58026.1 - 4.9e-10 39.4 0.0 0.0002 21.1 0.0 3.5 2 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F NPP1 PF05630.11 CDJ58026.1 - 0.15 12.1 1.0 0.26 11.4 1.0 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Metallophos PF00149.28 CDJ58027.1 - 1.1e-07 32.6 0.0 1.8e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DEAD PF00270.29 CDJ58028.1 - 7.1e-11 42.2 0.0 6.3e-06 26.1 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58028.1 - 1.4e-10 41.5 0.0 4.7e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cupin_3 PF05899.12 CDJ58029.1 - 0.036 13.8 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF974 PF06159.13 CDJ58030.1 - 7.7e-16 58.6 2.6 8.1e-11 42.2 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF974) Transglut_C PF00927.22 CDJ58030.1 - 0.0017 18.4 0.5 0.022 14.9 0.0 2.4 2 1 1 3 3 3 1 Transglutaminase family, C-terminal ig like domain DUF2393 PF09624.10 CDJ58030.1 - 0.0033 17.4 0.1 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2393) Gryzun-like PF12742.7 CDJ58030.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF3122 PF11320.8 CDJ58030.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) YjbF PF11102.8 CDJ58030.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 1 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Peptidase_M16 PF00675.20 CDJ58031.1 - 1.3e-42 145.3 1.9 2e-42 144.7 0.0 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ58031.1 - 1.8e-30 106.3 0.0 3.5e-18 66.3 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CDJ58031.1 - 9.2e-29 100.6 0.0 3.9e-27 95.2 0.0 2.6 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 STI1 PF17830.1 CDJ58031.1 - 0.13 12.2 0.0 18 5.3 0.0 3.0 2 1 1 3 3 3 0 STI1 domain Asp PF00026.23 CDJ58032.1 - 1.3e-60 205.5 0.0 1.2e-41 143.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ58032.1 - 5.1e-13 49.6 0.0 7.5e-10 39.3 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDJ58032.1 - 0.02 15.5 0.0 7.3 7.3 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease Btz PF09405.10 CDJ58033.1 - 6.1e-05 23.3 0.5 7.6e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Amidohydro_2 PF04909.14 CDJ58035.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CDJ58035.1 - 3.7e-07 29.8 0.0 7.9e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family AsnA PF03590.15 CDJ58036.1 - 0.1 12.3 0.2 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 Aspartate-ammonia ligase PEP-utilisers_N PF05524.13 CDJ58036.1 - 0.51 10.5 4.4 0.48 10.6 0.2 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal V-SNARE PF05008.15 CDJ58036.1 - 1.5 9.3 8.1 0.52 10.7 2.2 2.7 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Syntaxin_2 PF14523.6 CDJ58036.1 - 3.8 7.9 9.9 53 4.3 9.9 2.2 1 1 0 1 1 1 0 Syntaxin-like protein Mod_r PF07200.13 CDJ58036.1 - 9.3 6.4 13.3 2.8e+02 1.5 13.3 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ribosomal_L28 PF00830.19 CDJ58037.1 - 1.4e-06 28.4 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L28 family HCNGP PF07818.13 CDJ58041.1 - 5.3e-05 23.8 0.5 0.00012 22.6 0.0 1.8 2 0 0 2 2 2 1 HCNGP-like protein DUF1917 PF08939.10 CDJ58041.1 - 4 7.3 5.2 3.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) DUF2633 PF11119.8 CDJ58041.1 - 8.3 6.4 7.1 16 5.5 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) GET2 PF08690.10 CDJ58042.1 - 0.00072 19.3 12.6 0.001 18.8 12.6 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 CCDC32 PF14989.6 CDJ58042.1 - 0.0031 17.5 2.0 0.0031 17.5 2.0 2.1 2 0 0 2 2 2 1 Coiled-coil domain containing 32 Spt20 PF12090.8 CDJ58042.1 - 0.012 15.2 6.5 0.012 15.2 6.5 2.2 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ58042.1 - 0.035 13.0 16.0 0.013 14.5 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt5_N PF11942.8 CDJ58042.1 - 0.038 15.0 6.4 0.038 15.0 6.4 2.7 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF1645 PF07816.11 CDJ58042.1 - 0.47 11.0 10.9 0.42 11.2 9.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) SPT6_acidic PF14632.6 CDJ58042.1 - 0.76 10.4 14.2 0.31 11.6 6.6 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ndc1_Nup PF09531.10 CDJ58042.1 - 1.2 7.7 8.5 1.6 7.4 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TraT PF05818.12 CDJ58042.1 - 1.3 8.7 7.9 0.82 9.3 6.0 1.7 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF572 PF04502.13 CDJ58042.1 - 1.5 8.3 11.1 2 8.0 11.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) XAP5 PF04921.14 CDJ58042.1 - 2.6 7.8 11.9 2.9 7.7 2.0 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator FAM176 PF14851.6 CDJ58042.1 - 5.8 6.6 13.2 4.8 6.8 0.5 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_S64 PF08192.11 CDJ58042.1 - 7.7 4.9 9.5 9.5 4.6 9.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pep1_7 PF17232.2 CDJ58042.1 - 8.1 7.0 15.1 1.1 9.8 4.0 3.1 3 0 0 3 3 3 0 Elicitor peptide 1-7 Coilin_N PF15862.5 CDJ58042.1 - 9.2 6.1 15.0 4.2 7.2 3.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus AnfO_nitrog PF09582.10 CDJ58042.1 - 9.4 5.5 8.9 1.2 8.4 2.3 2.1 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PRCC PF10253.9 CDJ58043.1 - 0.0035 18.2 13.6 0.048 14.5 8.1 2.1 2 0 0 2 2 2 2 Mitotic checkpoint regulator, MAD2B-interacting Gti1_Pac2 PF09729.9 CDJ58043.1 - 0.021 14.9 4.5 0.078 13.1 2.0 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Transposase_21 PF02992.14 CDJ58043.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Apt1 PF10351.9 CDJ58043.1 - 0.23 10.3 11.7 0.046 12.6 7.8 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain BAF1_ABF1 PF04684.13 CDJ58043.1 - 0.31 10.1 9.2 1.3 7.9 3.1 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Hamartin PF04388.12 CDJ58043.1 - 0.44 9.1 12.8 0.16 10.6 7.8 2.0 2 0 0 2 2 2 0 Hamartin protein Apc15p PF05841.11 CDJ58043.1 - 0.52 11.1 9.9 1.7 9.5 0.2 2.5 2 0 0 2 2 2 0 Apc15p protein RskA PF10099.9 CDJ58043.1 - 0.56 10.5 30.8 1 9.6 18.1 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA OAD_gamma PF04277.13 CDJ58043.1 - 2.4 8.8 15.6 1.3 9.6 0.3 3.7 2 1 2 4 4 3 0 Oxaloacetate decarboxylase, gamma chain Med3 PF11593.8 CDJ58043.1 - 3.8 6.6 32.5 0.079 12.1 3.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDJ58043.1 - 8.3 6.0 21.6 0.24 11.0 8.0 2.2 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ58043.1 - 8.3 5.1 10.6 12 4.5 6.3 2.0 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 CDJ58043.1 - 8.7 4.8 22.3 1.4 7.4 15.7 2.0 2 0 0 2 2 2 0 Macoilin family WD40 PF00400.32 CDJ58044.1 - 7.1e-51 169.1 6.5 5.5e-09 36.5 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ58044.1 - 4.5e-20 71.7 0.0 0.00017 21.8 0.0 5.3 2 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ58044.1 - 8.6e-06 24.9 0.1 0.23 10.4 0.0 3.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDJ58044.1 - 2.9e-05 22.9 0.9 0.24 10.0 0.0 4.3 3 2 0 4 4 4 1 Nucleoporin Nup120/160 BUD22 PF09073.10 CDJ58044.1 - 0.0074 15.7 2.2 0.0074 15.7 2.2 2.0 2 0 0 2 2 2 1 BUD22 eIF2A PF08662.11 CDJ58044.1 - 0.01 15.7 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 CDJ58044.1 - 0.013 14.5 0.3 7.9 5.3 0.0 3.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 CDJ58044.1 - 0.26 10.6 0.0 16 4.7 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain SR-25 PF10500.9 CDJ58044.1 - 0.31 10.6 30.7 0.065 12.8 5.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4228 PF14009.6 CDJ58044.1 - 0.41 11.0 9.7 0.26 11.6 6.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) AF-4 PF05110.13 CDJ58044.1 - 0.47 8.5 26.8 0.065 11.3 11.1 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein TAF4 PF05236.14 CDJ58044.1 - 4.5 7.0 11.9 8.9 6.0 11.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Apt1 PF10351.9 CDJ58044.1 - 5.8 5.6 7.2 1.3 7.8 1.9 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ58044.1 - 9 4.7 10.0 0.55 8.7 4.0 1.8 2 0 0 2 2 2 0 Macoilin family Spt20 PF12090.8 CDJ58045.1 - 0.0035 17.0 9.6 0.0035 17.0 9.6 3.7 3 1 0 3 3 3 2 Spt20 family RRP7 PF12923.7 CDJ58045.1 - 0.0043 17.2 2.0 0.031 14.4 0.0 2.4 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SR-25 PF10500.9 CDJ58045.1 - 0.098 12.2 14.0 0.74 9.4 7.2 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Fer4_18 PF13746.6 CDJ58045.1 - 0.93 9.7 5.1 0.35 11.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain DEAD PF00270.29 CDJ58046.1 - 1.2e-24 87.1 0.0 3.7e-23 82.2 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ58046.1 - 0.0003 20.8 0.0 0.0003 20.8 0.0 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 CDJ58046.1 - 0.68 9.2 40.3 1.8 7.8 26.9 2.2 2 0 0 2 2 2 0 BUD22 FAM60A PF15396.6 CDJ58046.1 - 1.5 8.8 28.5 0.64 10.0 20.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A SPX PF03105.19 CDJ58046.1 - 3 7.7 32.5 0.21 11.5 5.8 2.2 2 0 0 2 2 2 0 SPX domain Cwf_Cwc_15 PF04889.12 CDJ58046.1 - 4.1 7.1 45.6 0.38 10.4 2.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CCSAP PF15748.5 CDJ58046.1 - 5 7.2 39.1 7.3 6.7 32.1 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PAT1 PF09770.9 CDJ58046.1 - 5.3 5.2 28.9 8.3 4.5 28.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ58046.1 - 6.2 5.0 34.7 2 6.6 0.7 2.4 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 CDJ58046.1 - 8.1 5.1 37.5 4.1 6.1 1.2 2.4 2 0 0 2 2 2 0 Presenilin ThiF PF00899.21 CDJ58047.1 - 5.8e-07 29.1 0.1 6.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family Dec-1 PF04624.14 CDJ58047.1 - 0.36 10.7 1.3 0.92 9.4 1.3 1.6 1 0 0 1 1 1 0 Dec-1 repeat Ank_2 PF12796.7 CDJ58048.1 - 3.1e-42 143.0 0.0 1.5e-16 60.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ58048.1 - 3.4e-28 97.7 0.1 3.8e-14 52.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ58048.1 - 2e-26 89.1 0.0 0.0002 21.6 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CDJ58048.1 - 3.7e-25 87.2 0.2 6.1e-05 23.3 0.0 6.3 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDJ58048.1 - 9.7e-18 64.0 0.1 2.1e-05 24.7 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) V_ATPase_I PF01496.19 CDJ58049.1 - 0.59 8.0 7.3 1.2 6.9 7.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nrap_D4 PF17405.2 CDJ58050.1 - 4.5e-27 94.8 0.2 8.4e-27 93.9 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CDJ58050.1 - 7.6e-19 68.4 0.0 1.2e-17 64.4 0.0 2.9 2 1 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 CDJ58050.1 - 8.7e-18 64.8 0.0 2.1e-17 63.6 0.0 1.6 1 1 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 CDJ58050.1 - 5.5e-16 58.7 2.7 2.5e-14 53.3 0.1 3.2 2 1 1 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 CDJ58050.1 - 2.5e-07 30.6 0.2 0.044 13.5 0.0 3.6 4 0 0 4 4 4 2 Nrap protein PAP/OAS-like domain DUF4157 PF13699.6 CDJ58050.1 - 0.84 9.9 3.8 0.62 10.3 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4157) Ydr279_N PF17745.1 CDJ58051.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein triple barrel domain NIF PF03031.18 CDJ58052.1 - 8.5e-17 61.4 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Myb_DNA-binding PF00249.31 CDJ58053.1 - 2.3e-10 40.5 0.0 1.7e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 CDJ58053.1 - 1.6e-09 37.4 9.1 4.3e-09 36.0 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 CDJ58053.1 - 1.5e-05 25.1 0.0 8.9e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 CDJ58053.1 - 0.0014 18.9 5.9 0.0014 18.9 5.9 2.4 2 0 0 2 2 2 1 C1 domain DUF3983 PF13137.6 CDJ58053.1 - 0.12 12.2 1.3 0.29 11.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Adeno_PIX PF03955.14 CDJ58053.1 - 7.3 6.8 14.3 2 8.6 8.9 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) SMC_N PF02463.19 CDJ58055.1 - 2.1e-32 112.4 0.0 2.3e-31 109.0 0.0 2.5 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDJ58055.1 - 1.3e-10 41.5 0.0 1.3e-10 41.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CDJ58055.1 - 3.4e-10 40.8 18.3 3.4e-10 40.8 18.3 7.1 2 2 1 4 4 2 1 AAA domain SMC_hinge PF06470.13 CDJ58055.1 - 9.9e-09 35.5 0.0 9.7e-08 32.3 0.0 2.8 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDJ58055.1 - 0.00086 19.2 0.1 0.0022 17.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ58055.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.8 CDJ58055.1 - 0.003 17.5 6.6 0.003 17.5 6.6 10.3 6 5 4 10 10 10 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 CDJ58055.1 - 0.0035 17.4 32.2 0.0035 17.4 32.2 6.6 4 2 2 6 6 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 CDJ58055.1 - 0.0066 16.5 13.6 0.0066 16.5 13.6 7.2 3 3 5 8 8 7 3 Afadin- and alpha -actinin-Binding DUF2388 PF09498.10 CDJ58055.1 - 0.016 15.2 7.1 5.1 7.1 3.2 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF3584 PF12128.8 CDJ58055.1 - 3.6 5.0 101.3 0.66 7.4 46.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CDJ58055.1 - 7.1 6.7 61.2 0.27 11.3 11.3 6.7 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) Vip3A_N PF12495.8 CDJ58055.1 - 8 6.3 10.3 13 5.6 0.1 3.0 2 1 0 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF812 PF05667.11 CDJ58055.1 - 8.4 5.1 99.4 0.03 13.2 41.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF812) CRAL_TRIO PF00650.20 CDJ58056.1 - 4.4e-27 94.7 0.1 6.5e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDJ58056.1 - 0.0043 17.2 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pkinase PF00069.25 CDJ58057.1 - 3.5e-08 33.2 0.0 8.2e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 CDJ58057.1 - 1.5e-07 31.1 0.0 9.1e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ58057.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Carcinustatin PF08261.12 CDJ58057.1 - 6 7.9 16.1 61 4.9 0.6 5.0 4 0 0 4 4 4 0 Carcinustatin peptide SNF2_N PF00176.23 CDJ58061.1 - 0.0016 17.3 0.7 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Transcript_VP30 PF11507.8 CDJ58061.1 - 0.022 14.8 0.5 0.035 14.2 0.5 1.3 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Piezo_RRas_bdg PF12166.8 CDJ58061.1 - 1.2 8.3 4.6 2.5 7.3 4.6 1.6 1 1 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Draxin PF15550.6 CDJ58061.1 - 4.2 7.1 6.6 5.4 6.8 6.6 1.1 1 0 0 1 1 1 0 Draxin Apt1 PF10351.9 CDJ58062.1 - 0.075 11.9 2.8 0.089 11.6 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ58062.1 - 0.44 10.4 5.4 0.58 10.0 5.4 1.1 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 CDJ58062.1 - 3.7 8.1 17.4 0.94 10.1 7.5 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain TFIIA PF03153.13 CDJ58063.1 - 0.036 14.1 38.7 0.045 13.8 38.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.8 CDJ58063.1 - 0.18 10.9 39.6 0.26 10.4 39.6 1.3 1 0 0 1 1 1 0 SprA-related family GREB1 PF15782.5 CDJ58063.1 - 0.19 8.8 36.3 0.22 8.6 36.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 CDJ58063.1 - 2.3 7.7 34.2 3 7.4 34.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.13 CDJ58063.1 - 3 6.3 40.3 3.8 6.0 40.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF966 PF06136.13 CDJ58063.1 - 3.3 7.4 38.1 4.4 6.9 38.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LAP1C PF05609.12 CDJ58063.1 - 5.8 5.9 34.0 7.8 5.5 34.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Spt20 PF12090.8 CDJ58064.1 - 0.00094 18.9 33.0 0.0024 17.5 14.0 9.8 9 1 1 10 10 10 3 Spt20 family DUF2722 PF10846.8 CDJ58064.1 - 0.0031 16.5 9.2 0.0031 16.5 9.2 9.7 7 2 0 7 7 7 3 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ58064.1 - 0.0037 16.9 1.4 0.0037 16.9 1.4 6.9 7 1 0 7 7 7 1 Nuclear RNA-splicing-associated protein DUF4736 PF15883.5 CDJ58064.1 - 0.004 16.9 0.5 0.004 16.9 0.5 6.3 7 0 0 7 7 7 1 Domain of unknown function (DUF4736) CLN3 PF02487.17 CDJ58064.1 - 0.0047 16.0 2.9 0.0047 16.0 2.9 5.3 6 0 0 6 6 6 1 CLN3 protein PIG-U PF06728.13 CDJ58064.1 - 0.011 14.8 0.2 0.011 14.8 0.2 5.7 5 2 1 6 6 6 0 GPI transamidase subunit PIG-U Med11 PF10280.9 CDJ58064.1 - 0.013 16.0 2.8 0.013 16.0 2.8 8.2 8 3 1 9 9 9 0 Mediator complex protein EOS1 PF12326.8 CDJ58064.1 - 0.096 12.6 22.0 0.13 12.2 1.0 5.7 6 0 0 6 6 6 0 N-glycosylation protein DUF3915 PF13054.6 CDJ58064.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) MecA PF05389.12 CDJ58064.1 - 4.2 6.9 36.5 0.11 12.1 4.9 5.9 6 0 0 6 6 6 0 Negative regulator of genetic competence (MecA) VCBS PF13517.6 CDJ58065.1 - 2.7e-14 53.5 0.3 2.4e-06 28.1 0.5 6.0 5 1 1 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAGE_N PF12440.8 CDJ58065.1 - 0.00061 20.4 3.3 0.00061 20.4 3.3 11.3 8 4 2 10 10 6 2 Melanoma associated antigen family N terminal Cyt_bd_oxida_II PF02322.15 CDJ58065.1 - 0.0022 17.4 6.9 0.034 13.5 0.9 2.5 2 0 0 2 2 2 2 Cytochrome bd terminal oxidase subunit II FG-GAP PF01839.23 CDJ58065.1 - 0.013 15.6 9.0 1.9 8.7 0.0 4.9 5 0 0 5 5 4 0 FG-GAP repeat RskA PF10099.9 CDJ58065.1 - 0.017 15.4 1.2 0.017 15.4 1.2 7.6 2 2 4 6 6 5 0 Anti-sigma-K factor rskA SIT PF15330.6 CDJ58065.1 - 0.022 15.2 0.3 0.022 15.2 0.3 4.8 7 1 1 8 8 6 0 SHP2-interacting transmembrane adaptor protein, SIT OppC_N PF12911.7 CDJ58065.1 - 0.047 13.7 0.0 0.21 11.6 0.0 2.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Tetraspanin PF00335.20 CDJ58065.1 - 0.091 12.5 0.0 0.73 9.5 0.0 2.2 1 1 0 1 1 1 0 Tetraspanin family PriA_C PF18074.1 CDJ58065.1 - 0.19 12.5 2.9 0.57 11.0 0.2 3.3 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain DUF4834 PF16118.5 CDJ58065.1 - 0.2 12.6 0.0 0.2 12.6 0.0 6.1 6 2 0 6 6 3 0 Domain of unknown function (DUF4834) KASH PF10541.9 CDJ58065.1 - 0.23 11.8 4.6 0.59 10.4 4.6 1.7 1 0 0 1 1 1 0 Nuclear envelope localisation domain FAM176 PF14851.6 CDJ58065.1 - 0.29 10.8 8.4 0.73 9.5 0.5 3.8 4 1 0 4 4 4 0 FAM176 family Itfg2 PF15907.5 CDJ58065.1 - 0.65 9.0 4.6 0.6 9.1 1.0 2.7 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 Tmemb_9 PF05434.11 CDJ58065.1 - 3.1 7.7 0.0 3.1 7.7 0.0 4.2 4 0 0 4 4 3 0 TMEM9 Rxt3 PF08642.10 CDJ58065.1 - 4.6 8.0 10.7 4.2 8.2 0.2 4.8 4 1 1 5 5 5 0 Histone deacetylation protein Rxt3 TFIIA PF03153.13 CDJ58065.1 - 7.4 6.5 80.9 5.9 6.8 7.2 4.2 1 1 1 4 4 4 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ58066.1 - 3.6e-05 24.1 0.1 3.6e-05 24.1 0.1 7.6 1 1 3 6 6 6 3 Anti-sigma-K factor rskA AF-4 PF05110.13 CDJ58066.1 - 0.0012 17.1 24.2 0.0012 17.1 24.2 6.0 3 3 2 6 6 6 1 AF-4 proto-oncoprotein SUIM_assoc PF16619.5 CDJ58066.1 - 0.013 15.6 3.0 0.013 15.6 3.0 8.6 5 3 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 FA_hydroxylase PF04116.13 CDJ58066.1 - 0.055 13.8 0.1 7.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily RskA PF10099.9 CDJ58069.1 - 0.00048 20.5 0.0 0.00048 20.5 0.0 20.6 3 2 12 15 15 15 1 Anti-sigma-K factor rskA DUF1059 PF06348.11 CDJ58071.1 - 7.4 6.9 6.8 16 5.9 0.3 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1059) Brix PF04427.18 CDJ58072.1 - 8.3e-19 68.4 0.0 1.4e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain FAM199X PF15814.5 CDJ58072.1 - 3.1 6.8 6.5 14 4.6 5.6 2.4 2 1 1 3 3 3 0 Protein family FAM199X DUF2681 PF10883.8 CDJ58072.1 - 8.5 6.9 9.0 10 6.6 8.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) SET PF00856.28 CDJ58073.1 - 6.3e-06 26.7 4.3 1.1e-05 25.8 0.0 3.2 3 1 0 3 3 3 1 SET domain Mon1 PF03164.14 CDJ58074.1 - 1.6e-54 185.6 0.0 4.4e-49 167.6 0.0 3.0 2 1 0 2 2 2 2 Trafficking protein Mon1 COMMD1_N PF17221.3 CDJ58075.1 - 4.2 7.7 7.3 0.53 10.6 2.8 1.8 2 0 0 2 2 2 0 COMMD1 N-terminal domain Aminotran_5 PF00266.19 CDJ58082.1 - 5.6e-73 246.0 0.0 2.9e-51 174.6 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V Activator_LAG-3 PF11498.8 CDJ58082.1 - 0.00013 21.1 11.3 0.00013 21.1 11.3 2.5 3 0 0 3 3 3 2 Transcriptional activator LAG-3 DegT_DnrJ_EryC1 PF01041.17 CDJ58082.1 - 0.00078 18.9 0.1 0.00078 18.9 0.1 2.1 3 0 0 3 3 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pex14_N PF04695.13 CDJ58082.1 - 0.0036 18.0 19.1 0.042 14.5 3.0 3.1 3 0 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Beta_elim_lyase PF01212.21 CDJ58082.1 - 0.024 13.9 0.3 0.062 12.6 0.3 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Spt20 PF12090.8 CDJ58082.1 - 0.26 10.9 36.5 1.1 8.8 7.7 2.3 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 CDJ58082.1 - 0.76 8.6 28.4 0.31 9.9 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 CDJ58082.1 - 4.4 7.5 7.7 2.9 8.1 1.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CDJ58082.1 - 4.6 5.9 10.7 2 7.1 3.3 2.1 2 0 0 2 2 2 0 Presenilin Suf PF05843.14 CDJ58082.1 - 5.3 6.9 15.7 1.1 9.2 5.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF5349 PF17298.2 CDJ58082.1 - 6.4 6.4 19.4 1.9 8.2 3.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5349) Connexin PF00029.19 CDJ58082.1 - 8.7 6.0 8.6 2.4 7.8 1.7 2.1 2 0 0 2 2 2 0 Connexin Pex26 PF07163.12 CDJ58082.1 - 9.4 5.4 17.1 4.7 6.4 6.1 2.3 2 0 0 2 2 2 0 Pex26 protein Spt20 PF12090.8 CDJ58083.1 - 0.21 11.2 3.0 0.29 10.7 3.0 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_C48 PF02902.19 CDJ58084.1 - 3.2e-10 40.2 0.0 3.2e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Exo_endo_phos PF03372.23 CDJ58086.1 - 0.017 14.7 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family MHC_I PF00129.18 CDJ58086.1 - 0.095 12.3 0.6 0.15 11.6 0.6 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 ABC_membrane PF00664.23 CDJ58087.1 - 3.1e-32 112.3 2.6 1.8e-28 100.0 2.6 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ58087.1 - 2.4e-29 102.6 0.0 1.1e-27 97.2 0.0 2.4 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ58087.1 - 1e-06 28.4 0.6 4.6e-06 26.2 0.3 2.1 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDJ58087.1 - 0.001 19.5 2.3 0.0045 17.4 2.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ58087.1 - 0.0012 19.1 0.1 0.059 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 CDJ58087.1 - 0.0032 16.3 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 CDJ58087.1 - 0.007 16.2 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 CDJ58087.1 - 0.011 15.5 0.2 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDJ58087.1 - 0.012 15.2 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ58087.1 - 0.015 15.3 0.0 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CDJ58087.1 - 0.015 15.5 0.5 0.22 11.8 0.5 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Aph-1 PF06105.12 CDJ58087.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Aph-1 protein AAA_29 PF13555.6 CDJ58087.1 - 0.023 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CDJ58087.1 - 0.029 13.6 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 CDJ58087.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CDJ58087.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 CDJ58087.1 - 0.059 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CDJ58087.1 - 0.11 12.9 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDJ58087.1 - 0.17 11.3 0.1 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Rad17 PF03215.15 CDJ58087.1 - 0.17 11.8 0.2 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 CDJ58087.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Thioredoxin PF00085.20 CDJ58088.1 - 8.7e-19 67.4 0.3 1.1e-06 28.6 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CDJ58088.1 - 3.7e-12 46.5 1.9 0.0024 17.8 0.2 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ58088.1 - 1.9e-06 28.3 0.1 0.13 12.7 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ58088.1 - 8.3e-06 26.1 0.7 0.64 10.4 0.0 4.0 4 1 0 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CDJ58088.1 - 0.002 17.6 3.4 2.9 7.2 0.1 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family TraF PF13728.6 CDJ58088.1 - 0.014 15.2 0.1 13 5.5 0.0 3.5 3 0 0 3 3 3 0 F plasmid transfer operon protein KaiB PF07689.12 CDJ58088.1 - 0.02 14.6 0.8 15 5.4 0.0 4.1 4 2 1 5 5 5 0 KaiB domain TrbC_Ftype PF09673.10 CDJ58088.1 - 0.94 9.6 4.1 11 6.2 0.1 3.9 3 2 2 5 5 5 0 Type-F conjugative transfer system pilin assembly protein AlaDh_PNT_N PF05222.15 CDJ58089.1 - 2.8e-41 141.0 0.1 3.2e-41 140.8 0.1 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh PF00389.30 CDJ58089.1 - 0.11 12.2 0.0 4.9 6.8 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Dehydrin PF00257.19 CDJ58090.1 - 0.00024 21.7 1.8 0.00024 21.7 1.8 6.8 4 2 2 7 7 7 1 Dehydrin Molybdopterin_N PF18364.1 CDJ58093.1 - 0.028 14.4 0.1 0.081 12.9 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain PKD_channel PF08016.12 CDJ58093.1 - 1.6 7.3 36.1 0.0049 15.6 11.9 4.4 4 1 1 5 5 5 0 Polycystin cation channel SLATT_1 PF18181.1 CDJ58093.1 - 2.6 8.0 5.4 31 4.5 0.0 3.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 ATP-synt_ab PF00006.25 CDJ58094.1 - 7.8e-58 195.6 0.0 1.3e-56 191.7 0.0 2.2 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ58094.1 - 1.2e-19 70.6 2.7 2.8e-18 66.2 2.7 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RskA PF10099.9 CDJ58094.1 - 4e-05 24.0 10.2 6.1e-05 23.4 10.2 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA ATPase PF06745.13 CDJ58094.1 - 0.0021 17.5 0.8 0.0021 17.5 0.8 1.9 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 CDJ58094.1 - 0.0072 15.5 0.3 0.0072 15.5 0.3 1.7 2 0 0 2 2 2 1 NB-ARC domain Med15 PF09606.10 CDJ58094.1 - 0.011 14.5 11.7 0.018 13.8 11.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA PF00004.29 CDJ58094.1 - 0.015 15.8 0.3 3.7 8.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rsc14 PF08586.10 CDJ58094.1 - 0.02 15.7 0.5 0.02 15.7 0.5 1.9 2 0 0 2 2 1 0 RSC complex, Rsc14/Ldb7 subunit DUF2844 PF11005.8 CDJ58094.1 - 0.023 14.7 3.5 0.045 13.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) DUF4746 PF15928.5 CDJ58094.1 - 0.028 13.8 0.3 0.052 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-L PF13092.6 CDJ58094.1 - 0.045 14.0 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 AAA_16 PF13191.6 CDJ58094.1 - 0.054 13.9 0.4 0.74 10.2 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain TFIIA PF03153.13 CDJ58094.1 - 0.072 13.1 8.3 0.15 12.0 8.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATPase_2 PF01637.18 CDJ58094.1 - 0.083 12.8 5.1 0.055 13.4 1.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CDJ58094.1 - 0.13 12.8 3.3 1.5 9.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDJ58094.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.2 2 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 CDJ58094.1 - 0.35 10.8 2.3 0.44 10.5 0.0 2.2 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 CDJ58094.1 - 0.49 10.7 6.5 17 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ58095.1 - 1.1e-06 28.9 45.8 3.9e-06 27.1 11.6 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 CDJ58095.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SARAF PF06682.12 CDJ58095.1 - 0.0018 18.0 23.2 0.0049 16.6 5.6 2.6 2 1 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis RRM_occluded PF16842.5 CDJ58095.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Dehydrin PF00257.19 CDJ58095.1 - 0.018 15.6 5.4 0.018 15.6 5.4 2.7 3 0 0 3 3 3 0 Dehydrin MMU163 PF17119.5 CDJ58095.1 - 1.8 7.7 6.0 0.48 9.5 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis RNase_H2_suC PF08615.11 CDJ58095.1 - 3.1 8.0 9.6 25 5.0 0.0 2.6 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Gcd10p PF04189.13 CDJ58096.1 - 1.1e-09 37.9 4.1 4.6e-06 26.0 2.6 2.3 1 1 1 2 2 2 2 Gcd10p family CCDC53 PF10152.9 CDJ58096.1 - 1.5 9.3 6.0 26 5.2 4.8 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 CDJ58096.1 - 2.5 7.7 12.4 1.1 8.8 7.9 2.1 2 0 0 2 2 2 0 Spt20 family Surface_antigen PF11054.8 CDJ58097.1 - 6.2e-15 55.5 1.5 7.3e-14 52.0 0.5 2.5 2 1 0 2 2 2 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ58098.1 - 2.9e-13 50.1 1.6 1.1e-12 48.2 0.4 2.3 2 1 0 2 2 2 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ58099.1 - 5.7e-15 55.6 3.6 4e-13 49.6 1.6 2.5 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen SDA1 PF05285.12 CDJ58102.1 - 0.00086 18.8 21.8 0.00086 18.8 21.8 1.9 2 0 0 2 2 2 1 SDA1 Nucleo_P87 PF07267.11 CDJ58102.1 - 0.0011 17.9 10.6 0.0011 17.9 10.6 1.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus capsid protein P87 Macoilin PF09726.9 CDJ58102.1 - 0.0019 16.9 19.0 0.0036 15.9 19.0 1.4 1 0 0 1 1 1 1 Macoilin family CDC45 PF02724.14 CDJ58102.1 - 0.16 10.2 22.3 0.26 9.5 22.3 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 CDJ58102.1 - 0.19 11.7 0.3 0.46 10.4 0.1 1.8 2 0 0 2 2 2 0 F-box-like SLC12 PF03522.15 CDJ58102.1 - 0.5 9.3 12.3 1.1 8.3 12.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ58102.1 - 0.79 8.1 1.6 1 7.7 1.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FRG2 PF15315.6 CDJ58102.1 - 1.4 9.0 23.0 0.38 10.9 19.6 1.7 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Med19 PF10278.9 CDJ58102.1 - 1.7 8.5 21.0 4 7.3 21.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hid1 PF12722.7 CDJ58102.1 - 2.2 6.3 18.7 3.2 5.7 18.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.12 CDJ58102.1 - 4.1 7.6 15.0 0.38 11.0 10.3 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family Bac_DnaA_C PF08299.11 CDJ58105.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix DUF4386 PF14329.6 CDJ58107.1 - 3.4 7.5 11.9 0.42 10.4 5.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) WW PF00397.26 CDJ58108.1 - 1.3e-05 25.2 1.5 2.9e-05 24.1 1.5 1.7 1 0 0 1 1 1 1 WW domain SR-25 PF10500.9 CDJ58108.1 - 0.00048 19.8 19.5 0.00048 19.8 19.5 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 CDJ58108.1 - 2.7 6.6 49.6 3.4 6.3 39.3 2.2 2 0 0 2 2 2 0 Caldesmon Slu7 PF11708.8 CDJ58109.1 - 0.003 17.4 0.3 0.0033 17.2 0.3 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor Pox_A12 PF04651.13 CDJ58109.1 - 0.51 10.4 4.9 0.7 9.9 4.9 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein TAF4 PF05236.14 CDJ58109.1 - 1.1 9.0 15.6 1.6 8.4 15.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Rrn6 PF10214.9 CDJ58109.1 - 1.5 7.2 5.7 1.6 7.1 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BAF1_ABF1 PF04684.13 CDJ58109.1 - 1.6 7.7 6.3 1.7 7.6 6.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SRP-alpha_N PF04086.13 CDJ58109.1 - 3.8 7.4 9.3 4.9 7.0 9.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.6 CDJ58109.1 - 4.2 6.1 7.7 4.5 6.0 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Herpes_UL25 PF01499.16 CDJ58109.1 - 7.8 4.9 9.4 10 4.5 9.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family G6PD_C PF02781.16 CDJ58110.1 - 5.4e-108 360.6 0.0 6.9e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CDJ58110.1 - 1.7e-33 116.7 0.0 2.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PEPCK_ATP PF01293.20 CDJ58110.1 - 0.23 10.1 0.1 0.33 9.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pantoate_transf PF02548.15 CDJ58111.1 - 4.1e-65 219.7 1.5 5.1e-35 121.1 0.1 2.3 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 CDJ58111.1 - 1.6e-23 83.3 0.1 2.8e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDJ58111.1 - 1.6e-07 31.1 0.1 4.6e-06 26.3 0.1 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.6 CDJ58111.1 - 0.034 13.6 0.2 0.062 12.7 0.2 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Rep_fac-A_C PF08646.10 CDJ58112.1 - 1.9e-27 95.8 0.2 4.3e-27 94.6 0.2 1.6 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDJ58112.1 - 3.7e-18 65.3 0.4 6e-14 51.8 0.1 2.4 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ58112.1 - 5.1e-10 39.2 0.0 2.6e-07 30.5 0.0 3.3 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CDJ58112.1 - 0.01 15.5 0.3 0.3 10.8 0.1 2.7 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 JAMP PF05571.12 CDJ58112.1 - 0.84 9.2 2.3 1.4 8.5 2.3 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Ribosomal_L21p PF00829.21 CDJ58113.1 - 6.5e-09 36.0 0.8 6.5e-09 36.0 0.8 1.8 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Spt20 PF12090.8 CDJ58113.1 - 5 6.7 25.3 2.2 7.8 12.7 2.2 2 0 0 2 2 2 0 Spt20 family Tim17 PF02466.19 CDJ58114.1 - 6.3e-22 78.1 3.8 9.2e-22 77.5 3.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family OB_NTP_bind PF07717.16 CDJ58115.1 - 7.8e-12 45.4 0.1 3.4e-11 43.3 0.1 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDJ58115.1 - 2.6e-10 40.6 0.1 2.6e-10 40.6 0.1 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) DUF4698 PF15769.5 CDJ58115.1 - 0.91 8.5 12.9 0.44 9.5 10.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) ERM PF00769.19 CDJ58115.1 - 1.4 8.7 8.4 0.4 10.5 5.2 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CRAL_TRIO PF00650.20 CDJ58117.1 - 6.4e-20 71.5 0.0 9.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain IL15 PF02372.15 CDJ58118.1 - 0.095 12.7 0.1 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 Interleukin 15 Popeye PF04831.13 CDJ58119.1 - 1.5e-11 44.6 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 CDJ58119.1 - 0.00015 21.8 0.2 0.04 14.0 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pex14_N PF04695.13 CDJ58121.1 - 1.5e-08 35.4 3.9 1.5e-08 35.4 3.9 8.0 3 2 3 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CDJ58121.1 - 0.0043 16.1 10.5 0.0043 16.1 10.5 5.1 4 2 0 4 4 4 2 Protein of unknown function (DUF2722) DUF2207 PF09972.9 CDJ58121.1 - 6.5 5.4 5.3 6.8 5.3 0.4 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Calponin PF00402.18 CDJ58122.1 - 0.13 12.0 3.0 37 4.1 0.1 4.6 3 0 0 3 3 3 0 Calponin family repeat KID PF02524.14 CDJ58122.1 - 2 8.9 8.7 3.6e+02 2.1 0.3 6.7 3 1 1 4 4 4 0 KID repeat Biotin_lipoyl PF00364.22 CDJ58122.1 - 4.7 7.1 9.8 8 6.4 0.4 4.2 2 1 1 3 3 3 0 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDJ58122.1 - 5.2 7.0 8.0 11 6.0 0.1 4.2 3 1 2 5 5 5 0 Biotin-lipoyl like DUF4342 PF14242.6 CDJ58123.1 - 0.0093 15.9 0.0 0.0093 15.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4342) Apt1 PF10351.9 CDJ58124.1 - 0.086 11.7 7.3 0.089 11.6 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ58124.1 - 0.11 11.0 12.9 0.15 10.6 12.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF5567 PF17722.1 CDJ58124.1 - 0.38 10.6 2.8 0.49 10.2 2.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5567) SOG2 PF10428.9 CDJ58124.1 - 0.38 9.9 15.9 0.44 9.7 15.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 CDJ58124.1 - 1.7 8.4 6.5 2.1 8.2 6.5 1.1 1 0 0 1 1 1 0 Rifin BAF1_ABF1 PF04684.13 CDJ58124.1 - 2.6 7.0 8.4 3.4 6.6 8.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Tmemb_cc2 PF10267.9 CDJ58124.1 - 2.7 7.1 5.4 2.8 7.0 5.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S64 PF08192.11 CDJ58124.1 - 3.8 5.9 8.9 3.9 5.9 8.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 SPX PF03105.19 CDJ58124.1 - 8.4 6.2 15.4 11 5.8 15.4 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 CDJ58125.1 - 1.3e-49 169.0 0.0 1.5e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58125.1 - 1e-15 57.8 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ58125.1 - 0.00022 20.6 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ58125.1 - 0.007 15.7 0.4 0.011 15.1 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ58125.1 - 0.025 14.5 0.5 0.043 13.7 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ58125.1 - 0.034 12.9 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CDJ58125.1 - 0.035 13.7 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UFD1 PF03152.14 CDJ58126.1 - 3.8e-69 231.6 0.0 6.3e-69 230.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 WD40 PF00400.32 CDJ58126.1 - 2.2e-08 34.6 0.9 0.046 14.6 1.4 5.1 4 0 0 4 4 4 1 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ58126.1 - 0.00045 20.2 0.0 0.00045 20.2 0.0 8.5 6 2 0 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CDJ58126.1 - 0.015 15.8 3.6 0.015 15.8 3.6 4.3 5 0 0 5 5 5 0 60s Acidic ribosomal protein AAA_23 PF13476.6 CDJ58126.1 - 0.048 14.2 38.4 0.027 15.0 14.3 3.3 3 0 0 3 3 3 0 AAA domain Utp14 PF04615.13 CDJ58126.1 - 0.068 11.7 38.5 0.0053 15.4 23.3 2.6 1 1 0 2 2 2 0 Utp14 protein DBINO PF13892.6 CDJ58127.1 - 0.00096 19.5 9.6 0.00096 19.5 9.6 5.2 7 0 0 7 7 7 1 DNA-binding domain DUF4179 PF13786.6 CDJ58128.1 - 7.6 7.1 5.6 1.1e+02 3.4 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) MRP-S31 PF15433.6 CDJ58130.1 - 9.9 5.7 25.8 1 9.0 13.1 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Caldesmon PF02029.15 CDJ58131.1 - 0.00035 19.5 0.2 0.00035 19.5 0.2 4.0 4 1 0 4 4 4 1 Caldesmon TFIIA PF03153.13 CDJ58131.1 - 0.001 19.1 33.8 0.001 19.1 33.8 5.8 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ58131.1 - 0.0014 18.2 4.1 0.0014 18.2 4.1 12.4 8 4 3 11 11 11 1 Nuclear RNA-splicing-associated protein DUF3042 PF11240.8 CDJ58132.1 - 6.8 6.8 11.5 0.086 12.9 2.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) MFS_2 PF13347.6 CDJ58133.1 - 0.002 16.8 1.5 0.0025 16.4 1.5 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Peptidase_M3 PF01432.20 CDJ58134.1 - 4.7e-25 88.8 0.0 7.2e-23 81.6 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M3 Androgen_recep PF02166.16 CDJ58134.1 - 1.9 7.3 3.4 2.6 6.8 3.4 1.1 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ58134.1 - 8 6.6 11.3 17 5.6 11.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Dynactin_p62 PF05502.13 CDJ58136.1 - 4.7e-07 29.0 6.3 4.7e-07 29.0 6.3 3.9 3 1 1 4 4 4 3 Dynactin p62 family DUF2722 PF10846.8 CDJ58136.1 - 0.00061 18.9 6.1 0.0095 14.9 3.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ58136.1 - 0.0055 16.4 4.4 0.0055 16.4 4.4 2.5 2 0 0 2 2 2 2 Spt20 family Med15 PF09606.10 CDJ58136.1 - 2.7 6.6 20.3 0.51 9.0 6.9 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ58137.1 - 0.0023 16.9 3.5 0.0023 16.9 3.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Polysacc_deac_1 PF01522.21 CDJ58137.1 - 0.54 10.2 6.5 0.48 10.3 0.7 2.5 2 0 0 2 2 2 0 Polysaccharide deacetylase DUF2681 PF10883.8 CDJ58137.1 - 1.8 9.0 37.1 0.04 14.3 7.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) AIM3 PF17096.5 CDJ58137.1 - 8.8 7.3 12.4 4.6 8.2 3.1 3.1 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 SUIM_assoc PF16619.5 CDJ58138.1 - 0.00062 19.8 0.0 0.00062 19.8 0.0 5.6 2 1 2 4 4 2 1 Unstructured region C-term to UIM in Ataxin3 NST1 PF13945.6 CDJ58138.1 - 0.018 15.2 28.9 0.26 11.4 11.1 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator Spt5_N PF11942.8 CDJ58138.1 - 0.05 14.6 1.7 0.05 14.6 1.7 3.4 3 2 0 3 3 2 0 Spt5 transcription elongation factor, acidic N-terminal SpoIIP PF07454.11 CDJ58138.1 - 0.11 11.9 18.6 0.45 9.9 5.3 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Afi1 PF07792.12 CDJ58138.1 - 0.11 12.9 16.1 0.31 11.5 2.9 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4746 PF15928.5 CDJ58138.1 - 0.6 9.5 12.0 1.8 7.9 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Dynamin_N PF00350.23 CDJ58138.1 - 0.8 9.7 5.8 6.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Dynamin family Spt20 PF12090.8 CDJ58138.1 - 2.1 7.9 67.9 0.12 12.0 23.3 3.2 3 0 0 3 3 3 0 Spt20 family DUF4820 PF16091.5 CDJ58138.1 - 2.4 7.5 15.8 1.8 7.9 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TCP PF03634.13 CDJ58138.1 - 2.6 8.6 29.1 0.88 10.1 8.5 2.9 3 0 0 3 3 3 0 TCP family transcription factor EIF4E-T PF10477.9 CDJ58138.1 - 3.1 6.5 35.0 0.41 9.4 29.7 1.8 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4638 PF15472.6 CDJ58138.1 - 3.2 7.4 17.4 3.3 7.4 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DUF3402 PF11882.8 CDJ58138.1 - 4.6 6.2 17.4 3.5 6.6 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Pannexin_like PF12534.8 CDJ58138.1 - 6 5.8 13.6 3.9 6.5 2.3 2.3 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 DUF4770 PF15994.5 CDJ58138.1 - 9.9 6.4 27.7 0.41 10.9 5.9 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4770) Glyoxalase PF00903.25 CDJ58139.1 - 2.4e-06 27.7 0.1 0.014 15.6 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ58139.1 - 0.15 12.3 9.1 0.26 11.6 0.2 3.6 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LMBR1 PF04791.16 CDJ58139.1 - 0.32 9.8 14.3 0.53 9.1 14.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein hDGE_amylase PF14701.6 CDJ58139.1 - 3 6.8 18.3 7.6 5.5 18.3 1.6 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CCDC154 PF15450.6 CDJ58140.1 - 0.0093 14.6 8.2 0.017 13.7 8.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 CENP-K PF11802.8 CDJ58140.1 - 0.014 15.0 8.8 0.079 12.5 5.1 2.2 2 0 0 2 2 2 0 Centromere-associated protein K SPX PF03105.19 CDJ58140.1 - 0.026 14.4 9.2 0.037 13.9 9.2 1.2 1 0 0 1 1 1 0 SPX domain Phage_GPO PF05929.11 CDJ58140.1 - 0.26 10.9 7.6 0.055 13.1 4.1 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase NRBF2 PF08961.10 CDJ58140.1 - 0.38 10.3 6.5 0.9 9.1 0.2 2.6 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 CDJ58140.1 - 0.95 10.0 11.7 1.6 9.3 0.2 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Pkinase PF00069.25 CDJ58141.1 - 2.9e-60 203.9 0.0 4.7e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 CDJ58141.1 - 4.7e-23 79.0 3.5 1.1e-08 34.1 1.5 3.6 3 0 0 3 3 3 3 EF hand Pkinase_Tyr PF07714.17 CDJ58141.1 - 3.2e-22 79.0 0.0 4.6e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ58141.1 - 3.4e-19 69.0 0.0 3.1e-11 43.5 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ58141.1 - 2.6e-15 55.1 4.6 0.00016 21.0 1.6 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDJ58141.1 - 2.6e-14 52.8 8.8 1.3e-06 28.2 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ58141.1 - 1.6e-13 49.4 10.1 7.5e-05 22.4 0.2 4.3 5 0 0 5 5 4 3 EF-hand domain Pkinase_fungal PF17667.1 CDJ58141.1 - 1.3e-06 27.5 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ58141.1 - 4.7e-05 22.8 0.0 0.00012 21.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ58141.1 - 0.0003 20.8 0.1 0.00095 19.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.6 CDJ58141.1 - 0.0014 18.9 0.3 2.2 8.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 CDJ58141.1 - 0.0042 17.0 0.9 0.39 10.7 0.1 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ58141.1 - 0.0079 16.4 0.1 1.3 9.3 0.0 3.0 3 0 0 3 3 3 1 Dockerin type I domain Kdo PF06293.14 CDJ58141.1 - 0.034 13.5 0.1 0.087 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3775 PF12616.8 CDJ58141.1 - 0.085 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) IL13 PF03487.13 CDJ58141.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Interleukin-13 Spc7 PF08317.11 CDJ58142.1 - 0.042 12.7 22.9 0.45 9.3 5.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3405 PF11885.8 CDJ58142.1 - 0.32 9.6 1.3 0.49 9.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Seryl_tRNA_N PF02403.22 CDJ58142.1 - 0.4 10.9 15.8 1.1 9.5 6.6 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PEARLI-4 PF05278.12 CDJ58142.1 - 0.55 9.8 8.7 1.6 8.3 8.7 1.8 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF1664 PF07889.12 CDJ58142.1 - 0.72 9.9 8.8 9.7 6.3 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 CDJ58142.1 - 1.5 9.1 15.6 0.4 11.0 6.7 3.1 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) CREPT PF16566.5 CDJ58142.1 - 1.7 8.8 12.1 0.71 10.0 5.7 2.6 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TSC22 PF01166.18 CDJ58142.1 - 4.4 7.7 9.3 0.41 11.0 2.8 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Ccdc124 PF06244.12 CDJ58143.1 - 5e-26 91.8 11.8 1.2e-24 87.3 11.8 2.0 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 LtuB PF17455.2 CDJ58143.1 - 0.15 12.7 0.5 0.31 11.7 0.2 1.7 2 0 0 2 2 2 0 Late transcription unit B VSG_B PF13206.6 CDJ58143.1 - 5.1 6.2 8.9 7.4 5.7 8.9 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF615 PF04751.14 CDJ58145.1 - 0.13 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Ribosomal_60s PF00428.19 CDJ58145.1 - 0.88 10.2 11.0 1.6 9.4 11.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Trypsin_2 PF13365.6 CDJ58148.1 - 4.2e-20 73.2 1.9 1.3e-19 71.6 1.9 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ58148.1 - 1.2e-10 41.6 0.0 3.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin HECT_2 PF09814.9 CDJ58149.1 - 0.00015 20.8 0.2 0.0019 17.1 0.0 2.5 3 1 0 3 3 3 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF866 PF05907.13 CDJ58149.1 - 0.016 15.2 0.3 0.016 15.2 0.3 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) DUF3006 PF11213.8 CDJ58149.1 - 0.046 13.9 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DEAD PF00270.29 CDJ58150.1 - 1.2e-13 51.2 4.1 3.8e-13 49.6 4.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58150.1 - 7.6e-11 42.3 1.6 1e-07 32.3 0.1 3.3 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ58150.1 - 8.9e-07 29.1 0.0 2.5e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ58150.1 - 0.00071 18.9 2.2 0.0013 18.1 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Spt20 PF12090.8 CDJ58150.1 - 0.00081 19.1 9.8 0.027 14.1 3.4 2.3 2 0 0 2 2 2 2 Spt20 family SecA_DEAD PF07517.14 CDJ58150.1 - 0.013 14.8 0.8 0.027 13.8 0.1 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain NACHT PF05729.12 CDJ58150.1 - 0.058 13.3 1.4 0.18 11.7 1.4 1.9 1 1 0 1 1 1 0 NACHT domain TFIIA PF03153.13 CDJ58150.1 - 0.066 13.2 18.9 0.036 14.1 7.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4484 PF14831.6 CDJ58150.1 - 0.75 9.8 7.4 6.3 6.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) CCDC53 PF10152.9 CDJ58150.1 - 6.5 7.1 13.2 0.62 10.5 0.2 3.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Apt1 PF10351.9 CDJ58150.1 - 8.6 5.1 8.7 1.5 7.6 4.5 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain HEAT PF02985.22 CDJ58152.1 - 0.012 15.7 8.6 0.69 10.3 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HEPN_LA2681 PF18733.1 CDJ58152.1 - 0.33 10.2 2.2 0.53 9.6 2.2 1.2 1 0 0 1 1 1 0 LA2681-like HEPN Sec61_beta PF03911.16 CDJ58154.1 - 5.3e-17 61.6 0.2 6.9e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Sec61beta family FH2 PF02181.23 CDJ58156.1 - 2.6e-37 128.8 0.3 9.1e-27 94.1 0.0 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain DDRGK PF09756.9 CDJ58156.1 - 0.32 10.6 0.0 0.32 10.6 0.0 7.3 9 0 0 9 9 9 0 DDRGK domain Bromodomain PF00439.25 CDJ58157.1 - 8.5e-21 73.8 0.4 1.6e-20 73.0 0.4 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CDJ58157.1 - 2.3e-11 44.0 0.1 4.8e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDJ58157.1 - 5.7e-09 36.0 0.1 9.4e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ58157.1 - 8.3e-07 29.3 1.1 1.7e-06 28.4 1.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDJ58157.1 - 0.01 15.9 0.1 0.089 12.9 0.1 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDJ58157.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein PCAF_N PF06466.11 CDJ58157.1 - 0.035 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_4 PF13420.7 CDJ58157.1 - 0.041 14.0 0.2 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L3 PF00297.22 CDJ58158.1 - 2.5e-10 39.9 4.1 1.1e-08 34.5 3.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 DUF1635 PF07795.11 CDJ58161.1 - 0.017 15.0 11.6 3.1 7.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) YajC PF02699.15 CDJ58161.1 - 0.034 14.0 4.3 2.8 7.9 0.2 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit PHD PF00628.29 CDJ58162.1 - 1.3e-05 25.0 2.8 5.1e-05 23.1 2.8 2.0 1 0 0 1 1 1 1 PHD-finger SLC12 PF03522.15 CDJ58163.1 - 0.00047 19.3 35.2 0.0067 15.5 7.3 2.0 2 0 0 2 2 2 2 Solute carrier family 12 RskA PF10099.9 CDJ58163.1 - 0.00056 20.3 0.9 0.00056 20.3 0.9 3.4 1 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF2052 PF09747.9 CDJ58163.1 - 0.00064 19.9 28.7 0.0099 16.0 14.7 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) TFIIA PF03153.13 CDJ58163.1 - 0.00091 19.3 65.3 0.042 13.8 38.6 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 CDJ58163.1 - 0.0026 16.8 14.3 0.0047 16.0 3.5 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 CDJ58163.1 - 0.0035 18.3 2.8 0.0035 18.3 2.8 4.3 2 2 2 4 4 3 2 Domain of unknown function (DUF4834) DUF2681 PF10883.8 CDJ58163.1 - 0.0048 17.3 2.9 0.0048 17.3 2.9 4.2 4 0 0 4 4 3 1 Protein of unknown function (DUF2681) Androgen_recep PF02166.16 CDJ58163.1 - 0.0064 15.4 7.6 0.0064 15.4 7.6 3.9 3 1 1 4 4 2 1 Androgen receptor EPL1 PF10513.9 CDJ58163.1 - 0.0067 16.8 19.7 0.0067 16.8 19.7 3.1 2 1 0 2 2 1 1 Enhancer of polycomb-like BUD22 PF09073.10 CDJ58163.1 - 0.0088 15.4 27.9 0.031 13.6 27.9 1.8 1 1 0 1 1 1 1 BUD22 PigN PF04987.14 CDJ58163.1 - 0.016 14.1 0.1 0.016 14.1 0.1 3.3 2 1 0 2 2 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF983 PF06170.12 CDJ58163.1 - 0.087 13.2 0.5 0.087 13.2 0.5 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF983) ALMT PF11744.8 CDJ58163.1 - 0.58 8.9 32.8 0.75 8.6 17.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Tmp39 PF10271.9 CDJ58163.1 - 0.64 9.0 3.3 2.7 6.9 0.2 2.1 2 0 0 2 2 2 0 Putative transmembrane protein DDRGK PF09756.9 CDJ58163.1 - 0.72 9.4 34.0 0.76 9.3 22.6 2.2 2 0 0 2 2 2 0 DDRGK domain SOG2 PF10428.9 CDJ58163.1 - 1.2 8.3 36.0 1.4 8.1 13.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SPX PF03105.19 CDJ58163.1 - 1.3 8.9 39.9 0.51 10.2 13.7 2.0 2 0 0 2 2 2 0 SPX domain V_ATPase_I PF01496.19 CDJ58163.1 - 1.6 6.6 27.6 0.59 8.0 2.4 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CDC27 PF09507.10 CDJ58163.1 - 1.7 8.0 37.4 0.96 8.8 19.7 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Herpes_DNAp_acc PF04929.12 CDJ58163.1 - 2.2 7.2 30.0 0.34 9.8 8.8 2.4 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.16 CDJ58163.1 - 2.4 8.2 32.0 3.9 7.5 16.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 CDJ58163.1 - 2.4 6.9 33.7 0.99 8.2 10.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Suf PF05843.14 CDJ58163.1 - 2.7 7.9 40.7 4.5 7.2 22.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.12 CDJ58163.1 - 2.9 8.1 24.9 2.2 8.5 11.9 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Dapper PF15268.6 CDJ58163.1 - 3 6.6 49.5 3.4 6.4 20.9 2.0 2 0 0 2 2 2 0 Dapper Gti1_Pac2 PF09729.9 CDJ58163.1 - 4.9 7.2 34.7 4.7 7.3 15.3 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family GPCR_chapero_1 PF11904.8 CDJ58163.1 - 5 6.5 21.4 0.22 11.0 6.6 2.2 2 0 0 2 2 2 0 GPCR-chaperone Smg8_Smg9 PF10220.9 CDJ58163.1 - 5.9 5.1 35.1 0.5 8.6 17.0 2.0 2 0 0 2 2 2 0 Smg8_Smg9 Miga PF10265.9 CDJ58163.1 - 6 5.7 26.7 0.5 9.3 11.2 2.1 2 0 0 2 2 2 0 Mitoguardin PAP1 PF08601.10 CDJ58163.1 - 6.8 6.3 48.8 5.8 6.5 14.9 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 DUF2828 PF11443.8 CDJ58163.1 - 7.5 4.5 24.9 1.8 6.5 14.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Nha1_C PF08619.10 CDJ58163.1 - 7.7 5.6 40.2 3.9 6.6 21.4 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Macoilin PF09726.9 CDJ58163.1 - 8 4.9 41.4 1.2 7.6 21.3 2.1 2 0 0 2 2 2 0 Macoilin family FAM60A PF15396.6 CDJ58163.1 - 10 6.1 36.1 1.3 9.0 14.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A UCH PF00443.29 CDJ58164.1 - 7.1e-20 71.6 0.1 7.1e-20 71.6 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ58164.1 - 1.3e-13 51.0 4.5 2.2e-13 50.3 4.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Macoilin PF09726.9 CDJ58164.1 - 0.011 14.3 3.6 0.013 14.1 3.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3788 PF12663.7 CDJ58164.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) Apt1 PF10351.9 CDJ58164.1 - 0.4 9.5 9.1 0.59 8.9 9.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ58164.1 - 6.2 4.8 15.2 8.7 4.3 15.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SPX PF03105.19 CDJ58164.1 - 9.6 6.0 15.0 14 5.4 15.0 1.1 1 0 0 1 1 1 0 SPX domain SDA1 PF05285.12 CDJ58165.1 - 8.7e-37 127.3 13.5 8.7e-37 127.3 13.5 3.1 2 1 1 3 3 3 1 SDA1 NUC130_3NT PF08158.12 CDJ58165.1 - 0.0001 22.5 8.7 0.0087 16.4 1.1 4.4 5 0 0 5 5 5 2 NUC130/3NT domain Caldesmon PF02029.15 CDJ58165.1 - 1.4 7.6 36.2 0.076 11.8 24.7 2.1 2 0 0 2 2 2 0 Caldesmon PDCD2_C PF04194.13 CDJ58166.1 - 1.1e-28 100.4 0.7 1.1e-28 100.4 0.7 2.8 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Arc_trans_TRASH PF08394.10 CDJ58166.1 - 0.1 13.0 0.6 0.1 13.0 0.6 2.7 3 0 0 3 3 3 0 Archaeal TRASH domain AP2 PF00847.20 CDJ58167.1 - 0.033 14.4 2.1 5.3 7.4 0.1 3.1 3 0 0 3 3 3 0 AP2 domain Nha1_C PF08619.10 CDJ58169.1 - 0.0033 16.7 9.5 0.0033 16.7 9.5 3.0 2 1 1 3 3 3 1 Alkali metal cation/H+ antiporter Nha1 C terminus Asparaginase_2 PF01112.18 CDJ58169.1 - 2.4 7.1 15.3 0.34 9.9 0.2 2.8 3 0 0 3 3 3 0 Asparaginase DUF1645 PF07816.11 CDJ58170.1 - 2 9.0 16.7 6.3 7.3 16.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Dsh_C PF12316.8 CDJ58170.1 - 2.5 8.5 13.4 3.1 8.1 13.4 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal IMUP PF15761.5 CDJ58170.1 - 2.7 8.7 14.4 0.43 11.3 8.8 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein Presenilin PF01080.17 CDJ58170.1 - 4.7 5.9 6.5 5.6 5.6 6.5 1.1 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 CDJ58171.1 - 0.0068 16.7 5.9 0.0068 16.7 5.9 6.5 4 2 0 5 5 5 2 Anti-sigma-K factor rskA EBP50_C PF09007.11 CDJ58172.1 - 0.061 14.3 4.6 4.1 8.4 0.8 2.5 2 0 0 2 2 2 0 EBP50, C-terminal DUF702 PF05142.12 CDJ58172.1 - 0.5 10.8 9.8 1.8 9.0 1.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF702) Hamartin PF04388.12 CDJ58172.1 - 1.1 7.9 5.6 1.5 7.4 5.6 1.1 1 0 0 1 1 1 0 Hamartin protein FAM176 PF14851.6 CDJ58172.1 - 1.3 8.7 4.6 0.78 9.4 0.7 2.2 2 0 0 2 2 2 0 FAM176 family PNISR PF15996.5 CDJ58172.1 - 1.9 8.7 18.6 0.22 11.8 2.3 2.7 2 1 0 3 3 3 0 Arginine/serine-rich protein PNISR TERB2 PF15101.6 CDJ58172.1 - 6.4 6.8 10.0 3.1 7.8 4.6 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF5427 PF10310.9 CDJ58172.1 - 6.9 5.5 17.9 0.79 8.6 6.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Choline_transpo PF04515.12 CDJ58173.1 - 2.1e-44 152.1 18.2 2.1e-44 152.1 18.2 2.5 3 0 0 3 3 3 1 Plasma-membrane choline transporter RAMP4 PF06624.12 CDJ58174.1 - 3.9e-23 81.3 0.4 4.5e-23 81.1 0.4 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MRP-S33 PF08293.11 CDJ58174.1 - 0.065 13.5 0.1 0.079 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 MORN PF02493.20 CDJ58175.1 - 3.3e-24 83.3 33.6 0.00013 21.6 0.0 8.0 7 0 0 7 7 7 6 MORN repeat Avl9 PF09794.9 CDJ58175.1 - 5.3e-10 38.5 1.9 1.2e-08 34.0 0.6 2.0 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 CDJ58175.1 - 0.00075 19.5 0.3 0.0013 18.7 0.3 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 CDJ58175.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis DUF2347 PF09804.9 CDJ58175.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) eIF3_p135 PF12807.7 CDJ58176.1 - 0.00059 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DSPc PF00782.20 CDJ58177.1 - 4.5e-19 68.6 0.1 3.8e-16 59.1 0.1 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 CDJ58177.1 - 0.02 14.8 0.0 0.07 13.0 0.0 2.0 1 0 0 1 1 1 0 Gelsolin repeat AAA_11 PF13086.6 CDJ58178.1 - 2.3e-43 148.9 2.4 1.9e-26 93.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 CDJ58178.1 - 9.5e-38 129.8 0.0 3.1e-37 128.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ58178.1 - 3.4e-11 43.2 0.0 1.2e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ58178.1 - 9.6e-10 39.0 0.0 3.4e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 CDJ58178.1 - 4.3e-05 22.9 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase dsrm PF00035.26 CDJ58178.1 - 8.9e-05 23.1 0.2 0.056 14.2 0.0 3.4 4 0 0 4 4 3 1 Double-stranded RNA binding motif DUF2075 PF09848.9 CDJ58178.1 - 0.0003 20.1 0.3 0.056 12.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDJ58178.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 CDJ58178.1 - 0.0021 17.6 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CDJ58178.1 - 0.0022 18.0 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CDJ58178.1 - 0.0089 15.8 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CDJ58178.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 CDJ58178.1 - 0.021 15.2 0.0 0.078 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ58178.1 - 0.068 12.9 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 CDJ58178.1 - 0.071 13.5 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 CDJ58178.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDJ58178.1 - 0.073 12.4 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 CDJ58178.1 - 0.095 12.2 0.3 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain G-patch PF01585.23 CDJ58179.1 - 1.3e-14 53.8 1.1 2.2e-14 53.1 1.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDJ58179.1 - 0.00038 20.5 0.4 0.0011 19.0 0.4 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDJ58179.1 - 0.00094 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBP4 PF07960.11 CDJ58179.1 - 0.053 13.4 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 CBP4 COPI_assoc PF08507.10 CDJ58181.1 - 0.011 15.7 0.2 0.014 15.4 0.2 1.2 1 0 0 1 1 1 0 COPI associated protein CD20 PF04103.15 CDJ58181.1 - 6.3 6.9 8.2 37 4.4 8.2 2.0 1 1 0 1 1 1 0 CD20-like family K-box PF01486.17 CDJ58184.1 - 0.019 15.1 4.2 0.12 12.6 1.3 2.9 2 2 1 3 3 3 0 K-box region PDZ PF00595.24 CDJ58185.1 - 2.2e-05 24.7 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ58185.1 - 2.5e-05 24.0 0.0 0.00023 20.9 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDJ58185.1 - 0.019 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RskA PF10099.9 CDJ58186.1 - 0.0047 17.2 14.9 0.0047 17.2 14.9 7.2 5 3 0 7 7 7 1 Anti-sigma-K factor rskA PAP2 PF01569.21 CDJ58187.1 - 2.6e-21 75.8 1.5 2.6e-21 75.8 1.5 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ58187.1 - 0.0033 17.9 6.2 0.082 13.5 0.4 3.5 3 0 0 3 3 3 2 PAP2 superfamily C-terminal PAP2 PF01569.21 CDJ58188.1 - 1.7e-21 76.4 1.2 1.7e-21 76.4 1.2 2.0 3 0 0 3 3 3 1 PAP2 superfamily DUF4059 PF13268.6 CDJ58188.1 - 0.068 13.6 2.5 0.074 13.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF5090 PF17009.5 CDJ58188.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ADK PF00406.22 CDJ58189.1 - 9.5e-54 181.6 0.0 1.5e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDJ58189.1 - 3.7e-27 95.4 2.5 5e-27 95.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain ADK_lid PF05191.14 CDJ58189.1 - 2.9e-16 59.2 0.0 8.9e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CDJ58189.1 - 1.5e-07 31.7 0.2 1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CDJ58189.1 - 3.8e-05 24.1 8.9 0.0011 19.3 0.1 3.2 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDJ58189.1 - 0.0002 21.9 0.1 0.0012 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Hydrolase_4 PF12146.8 CDJ58190.1 - 9.5e-06 25.0 0.5 0.18 11.0 0.0 3.3 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ58190.1 - 9.7e-05 22.1 0.1 0.015 15.0 0.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ58190.1 - 0.079 12.4 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDJ58190.1 - 0.086 12.6 0.2 1.1 9.0 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Asp2 PF16929.5 CDJ58190.1 - 0.29 10.1 0.4 0.51 9.2 0.0 1.5 2 0 0 2 2 2 0 Accessory Sec system GspB-transporter INTS5_N PF14837.6 CDJ58191.1 - 0.0077 15.9 3.2 4.4 6.8 0.0 3.3 3 0 0 3 3 3 2 Integrator complex subunit 5 N-terminus Ank_2 PF12796.7 CDJ58192.1 - 4.2e-38 129.8 0.3 3.3e-13 50.0 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ58192.1 - 2.5e-29 101.3 0.2 1.4e-05 25.5 0.0 7.3 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ58192.1 - 2.2e-27 94.7 4.2 0.0001 22.5 0.0 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ58192.1 - 6.4e-26 87.6 0.6 0.032 14.8 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 CDJ58192.1 - 4.4e-19 68.0 2.6 0.082 13.4 0.0 10.0 11 0 0 11 11 11 5 Ankyrin repeat AAA_23 PF13476.6 CDJ58192.1 - 3.6 8.0 10.7 1.9 8.9 4.1 2.5 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CDJ58192.1 - 3.6 7.5 27.2 0.4 10.6 11.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CDJ58193.1 - 5.5e-07 30.2 0.1 0.1 13.5 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ECH_2 PF16113.5 CDJ58194.1 - 3.5e-92 309.4 0.0 4.6e-77 259.8 0.0 2.2 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDJ58194.1 - 9.8e-27 93.9 0.0 4.5e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase TFIIA PF03153.13 CDJ58194.1 - 0.015 15.3 1.7 0.015 15.3 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 CDJ58194.1 - 1.3 7.0 4.5 1.8 6.5 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 CDJ58194.1 - 1.8 8.1 10.5 0.37 10.4 5.5 1.9 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 CDJ58194.1 - 9.5 6.4 14.8 37 4.5 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MMR_HSR1 PF01926.23 CDJ58195.1 - 1.4e-12 47.7 0.0 3.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ58195.1 - 2.4e-10 40.3 0.0 1e-08 35.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDJ58195.1 - 3.2e-08 33.2 0.2 4.5e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 Bacterial TniB protein RsgA_GTPase PF03193.16 CDJ58195.1 - 0.00022 21.2 0.5 0.061 13.2 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CDJ58195.1 - 0.0047 16.5 1.2 0.18 11.3 0.1 3.1 3 1 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.6 CDJ58195.1 - 0.0087 16.5 3.1 0.0087 16.5 3.1 2.2 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 CDJ58195.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CDJ58195.1 - 0.061 12.6 0.2 0.31 10.3 0.2 2.2 1 1 0 1 1 1 0 Septin Rrf2 PF02082.20 CDJ58195.1 - 0.07 13.5 0.2 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator AAA_29 PF13555.6 CDJ58195.1 - 0.082 12.7 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 CDJ58195.1 - 0.13 11.2 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 CDJ58195.1 - 0.15 11.6 0.0 8.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.23 CDJ58195.1 - 0.31 11.1 4.6 0.24 11.4 0.6 2.7 2 1 0 2 2 2 0 Dynamin family Ribosomal_60s PF00428.19 CDJ58195.1 - 0.35 11.5 11.5 0.42 11.2 4.7 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein EFG_C PF00679.24 CDJ58196.1 - 9.3e-24 83.3 0.1 1.2e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CDJ58196.1 - 5.3e-05 23.0 0.1 0.00013 21.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV RAP PF08373.10 CDJ58197.1 - 1.4e-21 76.3 0.1 3.8e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 CDJ58197.1 - 0.012 15.7 1.5 0.017 15.3 0.0 2.0 2 0 0 2 2 2 0 REase_MTES_1575 Ribosomal_60s PF00428.19 CDJ58198.1 - 0.014 16.0 7.2 0.014 16.0 7.2 7.1 3 1 1 4 4 4 0 60s Acidic ribosomal protein RPA43_OB PF17875.1 CDJ58198.1 - 1.1 9.9 13.1 2.6 8.7 0.1 3.3 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I POPLD PF08170.12 CDJ58198.1 - 8.3 6.8 10.3 9.5 6.6 0.4 3.0 2 0 0 2 2 2 0 POPLD (NUC188) domain Anticodon_1 PF08264.13 CDJ58199.1 - 2.6e-14 53.5 0.1 5.5e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Suf PF05843.14 CDJ58199.1 - 0.25 11.3 3.6 0.42 10.5 3.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 CDJ58199.1 - 6.5 5.5 8.8 11 4.7 8.8 1.3 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 CDJ58199.1 - 7.4 6.7 9.4 0.38 10.9 1.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 KH_8 PF17903.1 CDJ58200.1 - 5.7e-21 74.4 0.3 7.4e-21 74.0 0.3 1.2 1 0 0 1 1 1 1 Krr1 KH1 domain Roughex PF06020.11 CDJ58200.1 - 3.9 6.5 5.1 14 4.6 5.8 1.5 2 0 0 2 2 2 0 Drosophila roughex protein PP2C PF00481.21 CDJ58201.1 - 2.3e-23 83.2 0.0 8.5e-10 38.7 0.0 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDJ58201.1 - 0.00074 19.2 0.5 0.0026 17.4 0.5 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C RskA PF10099.9 CDJ58201.1 - 0.025 14.9 0.7 0.025 14.9 0.7 2.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Chorion_2 PF03964.15 CDJ58201.1 - 1.9 9.4 7.0 1.2 10.1 1.7 2.3 2 0 0 2 2 2 0 Chorion family 2 MBOAT PF03062.19 CDJ58202.1 - 1.6e-14 54.1 10.6 2.5e-14 53.4 10.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Presenilin PF01080.17 CDJ58202.1 - 1.6e-08 33.8 5.3 1.6e-08 33.8 5.3 2.3 2 0 0 2 2 2 1 Presenilin MBOAT_2 PF13813.6 CDJ58202.1 - 0.0003 21.0 3.9 0.00064 19.9 3.9 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LMBR1 PF04791.16 CDJ58202.1 - 0.005 15.8 5.5 0.009 15.0 5.5 1.5 1 0 0 1 1 1 1 LMBR1-like membrane protein Membralin PF09746.9 CDJ58202.1 - 0.26 10.3 9.9 0.47 9.4 9.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein Allexi_40kDa PF05549.11 CDJ58202.1 - 0.28 10.7 15.9 0.61 9.5 15.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein SID-1_RNA_chan PF13965.6 CDJ58202.1 - 1.2 7.4 8.4 2.3 6.5 8.4 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Otopetrin PF03189.13 CDJ58202.1 - 1.7 7.4 8.1 3.8 6.2 8.1 1.7 1 0 0 1 1 1 0 Otopetrin PEHE PF15275.6 CDJ58202.1 - 2.2 8.9 21.2 6.6 7.4 21.2 1.9 1 0 0 1 1 1 0 PEHE domain V_ATPase_I PF01496.19 CDJ58202.1 - 4.8 5.0 21.5 8.8 4.1 21.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 CDJ58202.1 - 5 6.2 11.5 13 4.8 11.5 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter PIH1 PF08190.12 CDJ58203.1 - 4.9e-07 29.4 0.1 1.3e-05 24.7 0.0 5.2 4 2 0 4 4 4 2 PIH1 N-terminal domain Patatin PF01734.22 CDJ58205.1 - 0.00067 19.9 3.7 0.0039 17.4 2.4 2.4 1 1 0 2 2 2 1 Patatin-like phospholipase DUF2722 PF10846.8 CDJ58205.1 - 0.038 12.9 4.2 3.1 6.7 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TMEM52 PF14979.6 CDJ58205.1 - 0.2 11.6 0.7 0.43 10.5 0.7 1.5 1 0 0 1 1 1 0 Transmembrane 52 TFIIA PF03153.13 CDJ58205.1 - 6.2 6.7 11.1 11 5.9 11.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ58205.1 - 6.6 6.7 12.2 13 5.8 11.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ThiF PF00899.21 CDJ58206.1 - 5.4e-17 62.0 11.0 4.1e-13 49.3 0.0 4.1 2 2 1 3 3 3 2 ThiF family ATG7_N PF16420.5 CDJ58206.1 - 1.5e-09 37.9 12.5 1.7e-06 27.9 5.1 5.1 4 1 2 6 6 6 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF5113 PF17140.4 CDJ58206.1 - 3 7.6 14.5 0.31 10.9 4.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Sec1 PF00995.23 CDJ58207.1 - 6.3e-17 62.0 1.1 6.8e-17 61.9 1.1 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_L11_N PF03946.14 CDJ58207.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain HOIP-UBA PF16678.5 CDJ58207.1 - 0.047 13.7 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair EBP50_C PF09007.11 CDJ58208.1 - 0.0041 18.1 8.9 0.0041 18.1 8.9 1.6 2 0 0 2 2 2 1 EBP50, C-terminal THOC7 PF05615.13 CDJ58208.1 - 0.033 14.5 3.2 0.033 14.5 3.2 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF3450 PF11932.8 CDJ58208.1 - 0.098 11.9 13.6 1.5 8.1 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 CDJ58208.1 - 0.11 12.7 18.2 0.2 11.8 18.2 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Plasmid_RAQPRD PF09686.10 CDJ58208.1 - 0.12 12.6 5.6 0.29 11.4 0.3 2.5 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) UPF0449 PF15136.6 CDJ58208.1 - 0.15 12.6 17.1 0.45 11.0 8.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Peptidase_S64 PF08192.11 CDJ58208.1 - 0.17 10.4 11.3 0.19 10.2 11.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Snapin_Pallidin PF14712.6 CDJ58208.1 - 0.48 10.9 8.7 0.61 10.5 0.4 2.3 1 1 1 2 2 2 0 Snapin/Pallidin HGD-D PF06050.13 CDJ58208.1 - 0.58 9.9 3.4 0.71 9.6 3.4 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Fes1 PF08609.10 CDJ58208.1 - 0.61 11.0 7.3 0.3 12.0 3.0 2.0 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 FapA PF03961.13 CDJ58208.1 - 0.83 8.2 10.5 1 7.9 10.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 CDJ58208.1 - 1 9.4 5.5 4.4 7.4 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) S36_mt PF10937.8 CDJ58208.1 - 1.2 10.8 7.3 0.42 12.2 1.9 2.0 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial Uso1_p115_C PF04871.13 CDJ58208.1 - 2 8.8 25.0 0.81 10.1 13.5 2.1 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 CDJ58208.1 - 2.4 8.7 23.5 9.3 6.8 7.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Syntaxin PF00804.25 CDJ58208.1 - 2.5 7.7 15.0 0.37 10.4 6.5 2.0 1 1 1 2 2 2 0 Syntaxin YabA PF06156.13 CDJ58208.1 - 4.1 8.1 13.2 2.1 9.0 3.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA WDCP PF15390.6 CDJ58208.1 - 5 5.4 11.5 0.41 9.0 6.2 1.6 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family ZapB PF06005.12 CDJ58208.1 - 7.2 7.1 22.0 1e+03 0.3 16.3 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 CDJ58208.1 - 7.2 6.5 19.4 8.6 6.3 7.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain TruD PF01142.18 CDJ58209.1 - 1e-16 60.8 9.6 5.1e-10 38.7 3.0 4.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF755 PF05501.11 CDJ58209.1 - 0.0026 18.0 9.2 0.0026 18.0 9.2 13.2 12 2 0 12 12 12 2 Domain of unknown function (DUF755) RskA PF10099.9 CDJ58209.1 - 0.0034 17.7 2.4 0.0034 17.7 2.4 13.0 2 2 8 11 11 11 4 Anti-sigma-K factor rskA TraT PF05818.12 CDJ58209.1 - 0.011 15.4 0.4 0.011 15.4 0.4 11.8 8 3 1 9 9 9 0 Enterobacterial TraT complement resistance protein HEM4 PF02602.15 CDJ58210.1 - 2e-13 50.3 11.7 3.8e-06 26.4 0.8 4.3 5 1 0 5 5 5 3 Uroporphyrinogen-III synthase HemD DUF2722 PF10846.8 CDJ58210.1 - 0.0048 15.9 0.0 0.0048 15.9 0.0 5.9 2 2 3 5 5 5 1 Protein of unknown function (DUF2722) DUF2722 PF10846.8 CDJ58211.1 - 1.3e-07 31.0 12.1 0.0005 19.1 2.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ58211.1 - 0.0019 18.6 2.9 0.13 12.6 0.2 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like SPX PF03105.19 CDJ58211.1 - 0.0039 17.2 5.4 0.0052 16.7 5.4 1.2 1 0 0 1 1 1 1 SPX domain Pex14_N PF04695.13 CDJ58211.1 - 0.014 16.0 20.8 0.21 12.3 8.5 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Protamine_P2 PF00841.19 CDJ58211.1 - 0.016 15.6 2.7 0.016 15.6 2.7 2.3 2 0 0 2 2 2 0 Sperm histone P2 RNase_H2_suC PF08615.11 CDJ58211.1 - 0.023 14.8 0.8 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SARAF PF06682.12 CDJ58211.1 - 0.029 14.0 10.1 0.061 13.0 1.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis TIMELESS PF04821.14 CDJ58211.1 - 0.032 13.5 0.0 0.032 13.5 0.0 2.0 1 1 1 2 2 2 0 Timeless protein Spore_coat_CotO PF14153.6 CDJ58211.1 - 0.2 11.6 14.6 0.24 11.3 4.2 2.4 2 0 0 2 2 2 0 Spore coat protein CotO eIF_4EBP PF05456.11 CDJ58211.1 - 0.23 11.4 9.9 2 8.4 2.1 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RskA PF10099.9 CDJ58211.1 - 1.3 9.3 24.0 7.2 6.9 0.6 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Nse4_C PF08743.10 CDJ58211.1 - 1.5 9.2 4.8 11 6.4 0.2 2.4 2 0 0 2 2 2 0 Nse4 C-terminal Roughex PF06020.11 CDJ58211.1 - 2.7 7.0 13.2 3.9 6.5 3.4 2.2 2 0 0 2 2 2 0 Drosophila roughex protein DUF3464 PF11947.8 CDJ58211.1 - 3 7.6 8.8 2.2 8.0 0.8 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 CDJ58211.1 - 3.6 5.4 6.2 0.37 8.6 0.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3043 PF11241.8 CDJ58211.1 - 5 7.1 7.5 8 6.5 1.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) DUF4366 PF14283.6 CDJ58211.1 - 5.2 7.1 7.3 4.4 7.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) CCSAP PF15748.5 CDJ58211.1 - 5.8 7.0 14.3 5.3 7.1 6.5 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SprA-related PF12118.8 CDJ58211.1 - 6.9 5.7 24.4 3.3 6.7 12.0 2.5 2 0 0 2 2 2 0 SprA-related family TERB2 PF15101.6 CDJ58211.1 - 7.8 6.5 12.1 14 5.7 3.8 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 dsDNA_bind PF01984.20 CDJ58211.1 - 9.5 6.5 22.8 7.6 6.9 8.1 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Ndc1_Nup PF09531.10 CDJ58212.1 - 2.6 6.6 0.0 2.6 6.6 0.0 9.7 5 3 4 9 9 9 0 Nucleoporin protein Ndc1-Nup Kelch_4 PF13418.6 CDJ58213.1 - 2.9e-10 40.0 0.0 0.21 11.6 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ58213.1 - 3.9e-10 39.6 0.2 0.00016 21.9 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDJ58213.1 - 1.2e-09 37.9 0.2 0.0003 20.7 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CDJ58213.1 - 1.4e-08 34.2 1.3 4.5e-05 22.9 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDJ58213.1 - 2.4e-08 34.1 1.9 0.0025 18.1 0.0 5.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ58213.1 - 3.1e-08 33.3 0.3 0.00051 19.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif RED_N PF07808.13 CDJ58213.1 - 4.4 6.8 15.2 1.5 8.3 0.5 2.6 2 0 0 2 2 2 0 RED-like protein N-terminal region PhoLip_ATPase_N PF16209.5 CDJ58215.1 - 7.6e-22 76.8 0.6 1.6e-21 75.7 0.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Spt20 PF12090.8 CDJ58215.1 - 4.5e-07 29.7 37.7 1.4e-05 24.9 7.6 2.4 2 0 0 2 2 2 2 Spt20 family Hydrolase_3 PF08282.12 CDJ58215.1 - 0.0025 17.6 0.0 0.0025 17.6 0.0 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DDHD PF02862.17 CDJ58215.1 - 0.0026 17.9 9.6 0.38 10.9 1.9 3.2 3 0 0 3 3 3 2 DDHD domain EPL1 PF10513.9 CDJ58215.1 - 0.0039 17.6 13.8 0.21 12.0 1.1 3.5 3 0 0 3 3 3 2 Enhancer of polycomb-like Presenilin PF01080.17 CDJ58215.1 - 0.0052 15.6 29.4 0.034 12.9 16.1 3.1 3 0 0 3 3 3 2 Presenilin TFIIA PF03153.13 CDJ58215.1 - 0.0073 16.4 48.8 0.053 13.5 17.9 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Hydrolase PF00702.26 CDJ58215.1 - 0.0075 16.6 11.7 0.33 11.2 0.3 4.2 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ58215.1 - 0.03 13.9 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 E1-E2 ATPase DUF4834 PF16118.5 CDJ58215.1 - 0.04 14.9 0.7 0.04 14.9 0.7 4.2 3 2 0 3 3 1 0 Domain of unknown function (DUF4834) FHIPEP PF00771.20 CDJ58215.1 - 0.041 12.4 5.8 0.15 10.5 0.3 2.4 2 0 0 2 2 2 0 FHIPEP family Cation_ATPase PF13246.6 CDJ58215.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RskA PF10099.9 CDJ58215.1 - 0.061 13.6 21.2 1.9 8.8 0.6 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SID-1_RNA_chan PF13965.6 CDJ58215.1 - 0.086 11.2 7.7 0.71 8.2 2.5 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1980 PF09323.10 CDJ58215.1 - 0.17 11.8 6.9 1.1 9.1 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TLP-20 PF06088.11 CDJ58215.1 - 0.31 10.9 14.3 0.8 9.6 1.9 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SpoIIP PF07454.11 CDJ58215.1 - 0.48 9.8 29.6 0.14 11.6 4.4 3.4 3 1 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ58215.1 - 0.58 9.2 10.7 1 8.3 1.1 2.5 2 0 0 2 2 2 0 CLN3 protein DUF4179 PF13786.6 CDJ58215.1 - 0.89 10.1 0.0 0.89 10.1 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4179) DUF3371 PF11851.8 CDJ58215.1 - 1.2 10.2 15.8 5.7 8.1 6.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) CDC45 PF02724.14 CDJ58215.1 - 1.8 6.7 32.6 2 6.6 6.2 3.2 3 0 0 3 3 3 0 CDC45-like protein CBP_BcsG PF11658.8 CDJ58215.1 - 3 6.1 11.2 1.8 6.9 0.8 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG RCR PF12273.8 CDJ58215.1 - 3.3 8.4 16.3 0.73 10.5 5.3 2.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Endostatin PF06482.11 CDJ58215.1 - 3.9 6.9 14.9 3.6 7.0 1.9 2.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Serinc PF03348.15 CDJ58215.1 - 4.1 6.2 8.9 13 4.6 4.8 2.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) TRAP_alpha PF03896.16 CDJ58215.1 - 8.8 5.4 19.8 7.1 5.7 0.9 3.2 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit GAGA_bind PF06217.12 CDJ58215.1 - 9.4 6.4 17.9 12 6.0 3.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family AMP-binding PF00501.28 CDJ58218.1 - 2.9e-78 263.4 0.0 8.3e-78 261.8 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ58218.1 - 2.6e-05 25.1 0.1 7.5e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Octopine_DH PF02317.17 CDJ58220.1 - 1e-37 129.6 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NTF2 PF02136.20 CDJ58221.1 - 1.2e-29 103.3 0.0 1.3e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 CDJ58221.1 - 0.004 17.1 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.6 CDJ58221.1 - 0.11 11.7 0.1 0.34 10.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Mitofilin PF09731.9 CDJ58222.1 - 6.8e-06 25.2 16.6 7.5e-06 25.1 16.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TFIIA PF03153.13 CDJ58222.1 - 2.4e-05 24.5 21.3 2.6e-05 24.4 21.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IER PF05760.12 CDJ58222.1 - 0.00023 21.6 11.2 0.00023 21.6 11.2 1.1 1 0 0 1 1 1 1 Immediate early response protein (IER) Hamartin PF04388.12 CDJ58222.1 - 0.0042 15.8 7.0 0.0047 15.7 7.0 1.1 1 0 0 1 1 1 1 Hamartin protein ASD2 PF08687.11 CDJ58222.1 - 0.021 14.4 13.8 0.028 14.0 13.8 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 SOG2 PF10428.9 CDJ58222.1 - 0.032 13.4 7.1 0.039 13.1 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF966 PF06136.13 CDJ58222.1 - 0.037 13.8 6.3 0.038 13.7 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Sin_N PF04801.13 CDJ58222.1 - 0.037 13.2 17.3 0.047 12.9 17.3 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region BAF1_ABF1 PF04684.13 CDJ58222.1 - 0.12 11.5 9.3 0.13 11.3 9.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 CDJ58222.1 - 0.13 11.3 5.7 0.14 11.2 5.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ58222.1 - 0.21 10.0 5.6 0.26 9.7 5.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4551 PF15087.6 CDJ58222.1 - 0.38 9.5 8.6 0.52 9.1 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Med13_C PF06333.12 CDJ58222.1 - 0.42 9.8 7.5 0.49 9.6 7.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Utp11 PF03998.13 CDJ58222.1 - 0.68 9.8 12.3 0.97 9.3 12.3 1.2 1 0 0 1 1 1 0 Utp11 protein DUF1631 PF07793.11 CDJ58222.1 - 0.71 8.2 27.5 0.9 7.9 27.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ndc1_Nup PF09531.10 CDJ58222.1 - 0.79 8.3 7.5 0.96 8.1 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ58222.1 - 0.89 7.7 20.8 1 7.6 20.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.9 CDJ58222.1 - 1 9.4 5.0 1.5 8.9 5.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 CDJ58222.1 - 1.7 7.4 7.2 2.1 7.1 7.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CDJ58222.1 - 1.7 7.3 12.3 2.4 6.8 12.3 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CDJ58222.1 - 3.2 7.7 6.6 4.7 7.2 6.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MTBP_C PF14920.6 CDJ58222.1 - 4.8 6.9 12.1 7 6.3 12.1 1.2 1 0 0 1 1 1 0 MDM2-binding DUF908 PF06012.12 CDJ58222.1 - 4.8 6.5 11.5 7.2 5.9 11.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) eIF-3_zeta PF05091.12 CDJ58222.1 - 4.9 6.0 12.2 7.4 5.4 12.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 CDJ58222.1 - 5.8 5.7 9.2 7.6 5.3 9.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SNARE PF05739.19 CDJ58223.1 - 3e-12 46.3 0.7 1.3e-11 44.3 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 CDJ58223.1 - 0.0012 17.0 0.1 0.0013 16.8 0.1 1.0 1 0 0 1 1 1 1 Prominin Turandot PF07240.11 CDJ58223.1 - 0.021 14.8 0.1 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Stress-inducible humoral factor Turandot Use1 PF09753.9 CDJ58223.1 - 0.023 14.4 0.7 0.025 14.3 0.7 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 T2SSF PF00482.23 CDJ58223.1 - 0.06 13.3 0.4 0.075 13.0 0.4 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Ribonuc_red_lgN PF00317.21 CDJ58223.1 - 0.087 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Fusion_gly PF00523.18 CDJ58223.1 - 0.1 10.8 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 PhoLip_ATPase_N PF16209.5 CDJ58224.1 - 1.8e-16 59.6 0.3 3.4e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDJ58224.1 - 5.2e-06 26.1 0.0 1.6e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase TFIIA PF03153.13 CDJ58224.1 - 0.0011 19.0 6.8 0.0011 19.0 6.8 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ58224.1 - 9.7 6.1 7.7 15 5.4 4.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MFS_1 PF07690.16 CDJ58225.1 - 7.1e-23 81.1 37.5 5.4e-21 74.9 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ58225.1 - 3e-09 36.3 21.0 1.9e-07 30.4 13.8 2.6 1 1 2 3 3 3 2 Sugar (and other) transporter BT1 PF03092.16 CDJ58225.1 - 0.48 8.6 5.2 0.69 8.1 0.1 2.1 1 1 1 2 2 2 0 BT1 family MFS_1_like PF12832.7 CDJ58225.1 - 0.73 8.6 11.2 0.81 8.5 5.6 2.8 2 1 1 3 3 3 0 MFS_1 like family RskA PF10099.9 CDJ58226.1 - 7.9e-05 23.0 0.0 7.9e-05 23.0 0.0 5.9 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ58226.1 - 0.00072 19.2 13.9 0.00072 19.2 13.9 6.3 4 3 0 4 4 4 1 Spt20 family DUF2722 PF10846.8 CDJ58226.1 - 0.0026 16.8 9.8 0.0026 16.8 9.8 6.6 5 2 0 7 7 7 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ58228.1 - 5.3e-07 30.1 11.5 5.3e-07 30.1 11.5 12.7 4 3 4 9 9 9 4 Anti-sigma-K factor rskA Mucin PF01456.17 CDJ58228.1 - 0.0097 15.9 0.8 0.0097 15.9 0.8 8.8 6 3 2 8 8 8 1 Mucin-like glycoprotein zf-C3HC4_3 PF13920.6 CDJ58234.1 - 1.6e-09 37.5 9.9 1.6e-09 37.5 9.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ58234.1 - 2.3e-08 33.7 10.8 2.3e-08 33.7 10.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ58234.1 - 2.6e-08 33.7 5.8 6.5e-08 32.5 5.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ58234.1 - 2.8e-08 33.5 11.5 7.2e-08 32.2 11.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ58234.1 - 1.2e-07 32.0 10.1 1.2e-07 32.0 10.1 1.7 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ58234.1 - 1.6e-07 31.0 9.6 4e-07 29.8 9.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDJ58234.1 - 5.2e-07 29.5 12.2 1.5e-06 28.0 12.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDJ58234.1 - 6.2e-06 26.3 7.4 6.2e-06 26.3 7.4 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 CDJ58234.1 - 0.0022 18.1 4.1 0.008 16.3 4.1 1.9 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 CDJ58234.1 - 0.0074 16.1 8.1 0.0074 16.1 8.1 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ58234.1 - 0.012 15.8 8.7 0.05 13.9 8.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CDJ58234.1 - 0.018 14.9 2.2 0.038 13.9 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein EFG_II PF14492.6 CDJ58234.1 - 0.13 12.3 0.4 1.2 9.3 0.3 2.7 3 0 0 3 3 3 0 Elongation Factor G, domain II zf-RING_10 PF16685.5 CDJ58234.1 - 0.55 10.4 7.9 1.4 9.1 7.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 CDJ58234.1 - 0.89 9.6 8.9 1.2 9.3 5.7 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 CDJ58234.1 - 3 8.9 5.0 18 6.5 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_11 PF17123.5 CDJ58234.1 - 4.5 7.1 6.9 9.6 6.0 6.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger TMEM65 PF10507.9 CDJ58235.1 - 1e-36 125.2 3.8 1e-36 125.2 3.8 2.6 3 0 0 3 3 3 1 Transmembrane protein 65 TFIIA PF03153.13 CDJ58235.1 - 0.23 11.4 11.0 0.34 10.9 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLATT_2 PF18183.1 CDJ58235.1 - 0.33 10.7 3.2 15 5.3 0.1 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 SARAF PF06682.12 CDJ58236.1 - 1.2 8.7 5.5 0.14 11.8 1.2 1.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ACCA PF03255.14 CDJ58236.1 - 4 7.3 6.3 10 5.9 6.3 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TFIIA PF03153.13 CDJ58237.1 - 0.0007 19.7 24.1 0.0011 19.1 24.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ58237.1 - 0.027 14.8 0.0 0.027 14.8 0.0 3.1 1 1 1 3 3 3 0 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ58237.1 - 0.094 11.9 15.9 0.15 11.3 15.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Lin-8 PF03353.15 CDJ58237.1 - 0.39 10.2 12.3 0.48 9.9 12.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 CDJ58237.1 - 0.59 8.3 19.9 0.69 8.1 19.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Folliculin PF11704.8 CDJ58237.1 - 0.95 9.3 6.1 2.1 8.2 6.1 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SLC12 PF03522.15 CDJ58237.1 - 1.6 7.6 8.3 2 7.4 8.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CDJ58237.1 - 1.8 6.6 11.8 2.4 6.2 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ChpXY PF10216.9 CDJ58237.1 - 2.1 7.4 4.6 2.9 6.9 4.6 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) Plasmodium_Vir PF05795.11 CDJ58237.1 - 7 6.0 6.3 8.1 5.8 6.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ALMT PF11744.8 CDJ58237.1 - 8.6 5.1 6.3 13 4.4 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SR-25 PF10500.9 CDJ58238.1 - 0.0054 16.4 4.7 0.0054 16.4 4.7 6.1 2 1 4 6 6 6 2 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ58238.1 - 0.009 16.3 40.8 0.009 16.3 40.8 7.2 2 2 6 8 8 8 1 Domain of unknown function (DUF755) K_channel_TID PF07941.11 CDJ58238.1 - 0.35 11.4 14.0 0.085 13.3 3.0 3.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain adh_short PF00106.25 CDJ58239.1 - 3e-11 43.2 22.1 4e-07 29.7 1.1 3.2 3 0 0 3 3 3 2 short chain dehydrogenase SCAI PF12070.8 CDJ58240.1 - 0.014 14.3 5.5 0.023 13.6 5.5 1.3 1 0 0 1 1 1 0 Protein SCAI zf-MIZ PF02891.20 CDJ58241.1 - 6.6e-16 57.8 8.3 7.5e-16 57.6 4.0 2.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 CDJ58241.1 - 4.7e-07 29.4 0.0 9.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain PHD_2 PF13831.6 CDJ58241.1 - 0.00076 19.0 5.4 0.00076 19.0 5.4 2.7 2 1 0 2 2 2 1 PHD-finger PHD PF00628.29 CDJ58241.1 - 0.027 14.3 16.3 0.076 12.9 7.1 2.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 CDJ58241.1 - 0.21 11.6 5.6 0.19 11.7 1.6 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_10 PF10058.9 CDJ58241.1 - 1.8 8.4 5.9 13 5.6 0.2 2.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Nse PF11789.8 CDJ58241.1 - 2.5 8.0 4.7 1.4 8.8 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MCM_OB PF17207.3 CDJ58242.1 - 3.5e-07 30.1 0.3 0.00049 19.9 0.2 2.1 1 1 1 2 2 2 2 MCM OB domain Peptidase_M16_M PF16187.5 CDJ58243.1 - 3.6e-05 23.2 0.0 0.0001 21.7 0.0 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDJ58243.1 - 0.0015 18.5 0.0 1.1 9.3 0.0 2.7 1 1 1 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ58243.1 - 0.06 13.3 0.5 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase M16 inactive domain HALZ PF02183.18 CDJ58245.1 - 1.4 9.2 18.2 0.13 12.6 1.2 3.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper Syntaxin_2 PF14523.6 CDJ58245.1 - 4.4 7.7 13.9 0.76 10.2 5.5 2.9 2 1 1 3 3 3 0 Syntaxin-like protein SHE3 PF17078.5 CDJ58245.1 - 4.7 6.8 13.6 0.14 11.9 2.3 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 PH PF00169.29 CDJ58246.1 - 4.2e-10 40.1 0.0 7e-05 23.3 0.0 4.3 3 2 1 4 4 4 3 PH domain DUF5542 PF17696.1 CDJ58247.1 - 0.22 11.7 1.5 0.45 10.7 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5542) PBP PF01161.20 CDJ58248.1 - 0.00042 20.6 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ecm29 PF13001.7 CDJ58249.1 - 7.2e-09 34.8 5.7 2.4e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 Proteasome stabiliser HEAT_EZ PF13513.6 CDJ58249.1 - 0.0065 16.9 14.7 0.21 12.1 0.0 7.4 7 0 0 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDJ58249.1 - 0.04 14.5 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDJ58249.1 - 0.06 13.6 0.1 0.06 13.6 0.1 6.5 6 0 0 6 6 6 0 HEAT repeat RTP1_C1 PF10363.9 CDJ58249.1 - 0.1 12.8 0.0 0.91 9.7 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CDJ58249.1 - 9.3 6.7 13.8 1.4 9.3 0.0 4.9 5 1 0 5 5 5 0 HEAT repeats DTW PF03942.15 CDJ58250.1 - 7.9e-23 81.2 0.7 8.4e-22 77.8 0.7 2.4 1 1 0 1 1 1 1 DTW domain CDC45 PF02724.14 CDJ58250.1 - 0.17 10.2 1.3 0.19 10.0 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt20 PF12090.8 CDJ58250.1 - 0.42 10.2 18.9 1.2 8.7 15.3 2.2 2 0 0 2 2 2 0 Spt20 family ARF7EP_C PF14949.6 CDJ58250.1 - 0.45 11.1 15.1 0.12 13.0 10.2 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus DUF3464 PF11947.8 CDJ58250.1 - 2.7 7.7 10.3 0.28 10.9 5.2 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4064 PF13273.6 CDJ58252.1 - 0.00041 20.6 1.8 7.1 7.0 0.0 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF4064) YdjM PF04307.14 CDJ58252.1 - 0.23 10.8 2.2 0.7 9.2 2.2 1.8 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase CPP1-like PF11833.8 CDJ58252.1 - 0.25 11.0 6.0 0.35 10.5 2.3 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TNFR_16_TM PF18422.1 CDJ58252.1 - 1.4 8.9 4.9 1.3 9.0 0.1 3.1 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Yip1 PF04893.17 CDJ58252.1 - 4.4 7.0 14.0 0.31 10.7 5.0 2.8 3 0 0 3 3 3 0 Yip1 domain XRN_M PF17846.1 CDJ58253.1 - 1.9e-52 178.7 7.8 1.1e-33 116.9 0.2 4.8 2 2 2 4 4 4 2 Xrn1 helical domain eIF3_subunit PF08597.10 CDJ58253.1 - 0.0047 16.9 7.7 0.0047 16.9 7.7 4.9 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit Exonuc_VII_L PF02601.15 CDJ58253.1 - 0.0057 16.3 3.3 0.0057 16.3 3.3 3.4 3 0 0 3 3 3 1 Exonuclease VII, large subunit DDHD PF02862.17 CDJ58253.1 - 0.054 13.6 0.2 0.054 13.6 0.2 4.2 4 1 0 4 4 4 0 DDHD domain CRT10 PF08728.10 CDJ58253.1 - 4.7 5.2 13.9 0.2 9.8 1.4 2.1 2 0 0 2 2 2 0 CRT10 TMEM65 PF10507.9 CDJ58254.1 - 8.2e-16 57.9 3.0 8.2e-16 57.9 3.0 4.2 4 1 1 5 5 5 1 Transmembrane protein 65 RskA PF10099.9 CDJ58254.1 - 0.0069 16.7 0.0 0.0069 16.7 0.0 5.9 2 1 3 5 5 5 3 Anti-sigma-K factor rskA Lin-8 PF03353.15 CDJ58255.1 - 8.8 5.8 45.5 4.9 6.6 36.5 2.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ58256.1 - 0.0011 18.7 20.7 0.0011 18.7 20.7 3.7 1 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein M_domain PF12938.7 CDJ58256.1 - 0.0017 18.2 5.3 0.0017 18.2 5.3 5.8 3 2 2 5 5 5 1 M domain of GW182 BUD22 PF09073.10 CDJ58257.1 - 0.00059 19.3 23.1 0.00059 19.3 23.1 2.7 3 0 0 3 3 3 1 BUD22 Vfa1 PF08432.10 CDJ58257.1 - 0.0023 18.3 22.7 0.0023 18.3 22.7 2.4 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 CDJ58257.1 - 0.0036 16.8 22.8 0.0036 16.8 22.8 2.2 2 0 0 2 2 2 1 SDA1 DUF3439 PF11921.8 CDJ58257.1 - 0.15 12.1 10.1 0.32 11.0 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MutS_IV PF05190.18 CDJ58258.1 - 4.4e-06 27.0 1.3 4.4e-06 27.0 1.3 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_V PF00488.21 CDJ58259.1 - 5.9e-40 137.3 0.1 6.4e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 MutS domain V Helicase_C PF00271.31 CDJ58260.1 - 1.4e-08 35.1 15.9 2.6e-08 34.2 0.0 4.9 4 0 0 4 4 4 2 Helicase conserved C-terminal domain TFIIA PF03153.13 CDJ58260.1 - 0.00032 20.8 36.4 0.00032 20.8 36.4 15.1 2 2 6 11 11 11 1 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 CDJ58262.1 - 5.2e-77 259.6 3.0 5.9e-77 259.4 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RskA PF10099.9 CDJ58263.1 - 5.6e-05 23.5 0.0 5.6e-05 23.5 0.0 4.8 2 2 1 3 3 3 1 Anti-sigma-K factor rskA DUF4207 PF13904.6 CDJ58263.1 - 0.00017 21.4 75.0 0.00017 21.4 75.0 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4207) Caldesmon PF02029.15 CDJ58263.1 - 0.014 14.2 61.5 0.032 13.0 61.5 1.6 1 0 0 1 1 1 0 Caldesmon MIF PF01187.18 CDJ58264.1 - 9.6e-21 74.2 0.1 1e-20 74.1 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CDJ58264.1 - 0.089 12.7 0.0 6.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme Utp14 PF04615.13 CDJ58265.1 - 0.7 8.4 47.9 0.85 8.1 47.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4813 PF16072.5 CDJ58265.1 - 2.3 7.8 22.9 3.1 7.4 22.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SOBP PF15279.6 CDJ58265.1 - 3.3 8.2 10.5 4.8 7.7 10.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S30 PF01577.16 CDJ58265.1 - 4.5 6.8 17.4 7.5 6.1 17.4 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease ketoacyl-synt PF00109.26 CDJ58266.1 - 4.8e-150 498.1 0.4 1.6e-74 250.7 0.0 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CDJ58266.1 - 2.4e-82 276.5 4.3 4.5e-43 147.6 0.5 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ58266.1 - 2.4e-81 269.5 0.7 1.8e-40 137.7 0.1 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CDJ58266.1 - 2.3e-80 268.8 0.0 5.5e-57 192.6 0.0 3.0 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.21 CDJ58266.1 - 1.7e-48 165.8 0.1 3.1e-48 164.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain ADH_zinc_N PF00107.26 CDJ58266.1 - 6.4e-27 94.1 0.1 5.9e-12 45.7 0.0 2.8 2 0 0 2 2 2 2 Zinc-binding dehydrogenase PP-binding PF00550.25 CDJ58266.1 - 1.7e-26 92.4 0.0 3.6e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 CDJ58266.1 - 1.1e-20 75.1 0.0 4.5e-09 37.4 0.0 3.0 2 0 0 2 2 2 2 Zinc-binding dehydrogenase adh_short PF00106.25 CDJ58266.1 - 6.7e-19 68.1 0.6 4.9e-11 42.4 0.0 3.6 4 0 0 4 4 4 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 CDJ58266.1 - 3.4e-15 56.5 0.2 4e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 CDJ58266.1 - 1.1e-09 38.1 12.2 0.00014 21.7 0.0 4.8 6 0 0 6 6 4 2 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 CDJ58266.1 - 5.2e-09 35.9 0.0 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 CDJ58266.1 - 8.4e-09 35.2 1.1 0.0037 16.7 0.2 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 CDJ58266.1 - 2.4e-07 30.2 0.0 0.0069 15.6 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDJ58266.1 - 9.9e-06 24.7 0.0 0.08 11.9 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CDJ58266.1 - 0.029 14.3 0.0 9.4 6.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 CDJ58266.1 - 0.045 13.8 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ACP_syn_III PF08545.10 CDJ58266.1 - 0.16 11.9 7.5 12 5.8 0.2 3.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AlaDh_PNT_C PF01262.21 CDJ58266.1 - 0.55 9.5 4.2 0.62 9.3 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 CDJ58266.1 - 1.1 8.9 7.7 6.9 6.3 0.0 3.9 5 0 0 5 5 4 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L38e PF01781.18 CDJ58267.1 - 2.6e-28 97.9 0.1 3.3e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Succ_CoA_lig PF13607.6 CDJ58267.1 - 0.071 12.9 0.4 0.081 12.7 0.4 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF1980 PF09323.10 CDJ58268.1 - 0.0015 18.5 0.5 0.0015 18.5 0.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1980) YcbB PF08664.10 CDJ58268.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 2.8 3 0 0 3 3 3 1 YcbB domain GNAT_acetyltr_2 PF13718.6 CDJ58268.1 - 0.0062 16.0 0.1 0.0062 16.0 0.1 2.8 3 0 0 3 3 3 1 GNAT acetyltransferase 2 Arginase PF00491.21 CDJ58268.1 - 0.0078 15.7 0.1 0.47 9.9 0.1 2.3 2 0 0 2 2 2 1 Arginase family Trp_oprn_chp PF09534.10 CDJ58268.1 - 0.011 15.6 2.2 0.017 14.9 0.0 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4834 PF16118.5 CDJ58268.1 - 0.044 14.8 1.0 0.044 14.8 1.0 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) PsaL PF02605.15 CDJ58268.1 - 0.062 13.0 0.2 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Spt20 PF12090.8 CDJ58268.1 - 0.069 12.8 50.8 0.47 10.0 10.0 4.0 4 0 0 4 4 4 0 Spt20 family DUF4449 PF14613.6 CDJ58268.1 - 0.21 11.7 15.1 0.23 11.6 2.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) ANAPC8 PF04049.13 CDJ58268.1 - 0.71 9.9 13.2 0.065 13.3 1.2 2.9 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 DUF2828 PF11443.8 CDJ58268.1 - 1.3 7.0 10.6 0.53 8.3 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Comm PF15957.5 CDJ58268.1 - 2.5 8.5 8.4 15 6.0 0.1 3.4 2 1 1 3 3 3 0 Commissureless RNase_Zc3h12a PF11977.8 CDJ58269.1 - 5.3e-05 23.0 0.0 5.3e-05 23.0 0.0 3.5 4 1 1 5 5 5 1 Zc3h12a-like Ribonuclease NYN domain DUF2722 PF10846.8 CDJ58269.1 - 0.29 10.0 0.0 0.29 10.0 0.0 11.3 7 4 0 9 9 9 0 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ58270.1 - 0.2 10.8 13.3 0.22 10.7 13.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SET PF00856.28 CDJ58271.1 - 2.8e-09 37.6 0.0 4.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 SET domain ABC1 PF03109.16 CDJ58272.1 - 5.9e-31 107.1 0.1 1.5e-30 105.8 0.1 1.7 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDJ58272.1 - 0.048 13.2 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Ribonuc_P_40 PF08584.11 CDJ58273.1 - 2.2e-07 30.4 0.0 3.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit Metallophos PF00149.28 CDJ58274.1 - 7.5e-06 26.6 0.0 2.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_23 PF13476.6 CDJ58274.1 - 0.0012 19.4 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MukB PF04310.12 CDJ58274.1 - 0.0065 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 MukB N-terminal TPR_2 PF07719.17 CDJ58275.1 - 7e-16 57.0 4.0 0.0012 18.8 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ58275.1 - 6.1e-13 48.0 3.6 0.00059 19.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ58275.1 - 8.2e-13 47.5 0.3 0.0058 16.7 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ58275.1 - 3.5e-10 39.8 4.4 0.014 16.2 0.1 4.6 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ58275.1 - 2.3e-09 36.6 0.1 0.09 12.9 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ58275.1 - 7.9e-09 35.5 3.7 8.3e-06 25.9 0.3 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ58275.1 - 2.2e-08 34.2 0.6 0.2 12.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ58275.1 - 5e-08 32.8 0.1 1.2 9.6 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ58275.1 - 7.6e-08 32.8 0.9 0.068 13.7 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ58275.1 - 3.6e-07 29.7 0.1 0.065 12.9 0.0 4.8 2 2 3 5 5 5 2 TPR repeat TPR_15 PF13429.6 CDJ58275.1 - 1.3e-05 24.5 0.0 2.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ58275.1 - 4.5e-05 24.0 2.6 0.0027 18.3 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ58275.1 - 0.00019 21.6 4.3 0.0051 17.1 0.4 3.7 2 1 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ58275.1 - 0.0019 18.4 2.0 0.5 10.6 0.2 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CDJ58275.1 - 0.0075 16.8 0.5 10 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CDJ58275.1 - 0.018 14.7 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 SNAP PF14938.6 CDJ58275.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 CDJ58275.1 - 0.086 12.7 2.1 0.88 9.5 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat HyaE PF07449.11 CDJ58275.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE FAST_1 PF06743.15 CDJ58277.1 - 0.00019 21.3 13.3 0.29 11.1 0.0 6.9 5 2 3 8 8 8 5 FAST kinase-like protein, subdomain 1 BTG PF07742.12 CDJ58277.1 - 0.046 13.6 0.3 0.15 12.0 0.3 1.8 1 0 0 1 1 1 0 BTG family Helicase_C PF00271.31 CDJ58279.1 - 1.5e-14 54.3 0.0 1.5e-14 54.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 CDJ58279.1 - 2.2e-10 40.3 2.9 0.00013 21.8 0.2 2.7 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Cdh1_DBD_1 PF18196.1 CDJ58279.1 - 0.0011 19.3 0.3 0.0011 19.3 0.3 7.1 4 1 2 7 7 7 1 Chromodomain helicase DNA-binding domain 1 TFIIA PF03153.13 CDJ58279.1 - 0.0024 17.9 10.5 0.0024 17.9 10.5 8.3 3 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 CDJ58279.1 - 0.21 11.6 4.1 0.37 10.8 0.8 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 CDJ58280.1 - 5.3e-09 35.8 0.0 5.5e-08 32.5 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain DUF4746 PF15928.5 CDJ58280.1 - 0.0026 17.3 5.7 0.0047 16.4 5.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Pkinase_Tyr PF07714.17 CDJ58280.1 - 0.03 13.6 0.1 6.7 5.9 0.1 2.5 3 0 0 3 3 3 0 Protein tyrosine kinase Vfa1 PF08432.10 CDJ58280.1 - 0.13 12.6 7.3 0.33 11.3 7.3 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.6 CDJ58280.1 - 0.14 12.2 1.5 0.36 10.8 1.5 1.8 1 0 0 1 1 1 0 Protein Family FAM60A Spidroin_N PF16763.5 CDJ58280.1 - 0.15 12.1 2.2 1.8 8.6 1.5 2.4 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF5580 PF17743.1 CDJ58280.1 - 0.16 10.5 3.6 0.24 9.9 3.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF2052 PF09747.9 CDJ58280.1 - 0.21 11.7 9.2 1.4 9.0 5.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NARP1 PF12569.8 CDJ58280.1 - 1.8 7.4 15.9 2.8 6.7 15.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.12 CDJ58280.1 - 4.9 6.4 16.4 10 5.4 16.4 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger PGA2 PF07543.12 CDJ58280.1 - 7.6 6.5 11.7 22 5.0 11.7 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 LOH1CR12 PF10158.9 CDJ58282.1 - 0.036 14.1 0.3 0.047 13.7 0.3 1.2 1 0 0 1 1 1 0 Tumour suppressor protein Ephrin_rec_like PF07699.13 CDJ58283.1 - 5.3 6.9 6.9 0.59 10.0 1.2 2.2 2 0 0 2 2 2 0 Putative ephrin-receptor like Nop14 PF04147.12 CDJ58285.1 - 0.085 11.1 25.4 0.1 10.8 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CDJ58285.1 - 0.21 10.3 12.3 0.32 9.7 12.3 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ58285.1 - 0.48 8.5 10.3 0.57 8.2 10.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 CDJ58285.1 - 0.9 8.6 16.5 1.2 8.2 16.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Smg8_Smg9 PF10220.9 CDJ58285.1 - 3.6 5.8 15.6 7.5 4.7 15.7 1.5 1 1 0 1 1 1 0 Smg8_Smg9 DUF3381 PF11861.8 CDJ58286.1 - 3.7 7.3 7.8 0.32 10.8 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF4407 PF14362.6 CDJ58286.1 - 6.5 6.0 9.8 8.1 5.7 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HA2 PF04408.23 CDJ58287.1 - 3.5e-19 69.1 0.0 3.5e-19 69.1 0.0 3.2 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ58287.1 - 8.6e-17 61.3 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ58287.1 - 1.1e-12 48.3 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ58287.1 - 0.00027 21.2 3.3 0.00093 19.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain DEAD PF00270.29 CDJ58287.1 - 0.00042 20.1 0.1 0.0013 18.6 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDJ58287.1 - 0.0014 19.0 0.0 0.0054 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ58287.1 - 0.0014 17.7 1.5 0.0031 16.6 1.5 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.19 CDJ58287.1 - 0.039 13.6 0.1 0.9 9.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ58287.1 - 0.061 13.7 0.0 0.061 13.7 0.0 4.2 2 1 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 CDJ58287.1 - 0.85 10.1 3.4 3.7 8.1 0.1 3.2 1 1 2 3 3 3 0 ABC transporter AAA_23 PF13476.6 CDJ58287.1 - 4 7.9 0.0 4 7.9 0.0 3.2 2 1 0 2 2 1 0 AAA domain ANAPC4_WD40 PF12894.7 CDJ58290.1 - 4.3e-09 36.5 0.0 0.00021 21.5 0.0 5.9 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ58290.1 - 1.3e-08 35.3 2.4 0.054 14.4 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDJ58290.1 - 0.013 14.5 0.1 4.1 6.3 0.0 4.2 6 0 0 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAST_1 PF06743.15 CDJ58291.1 - 0.014 15.3 0.0 6.7 6.7 0.0 4.3 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 IL12p40_C PF10420.9 CDJ58291.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus ALAD PF00490.21 CDJ58293.1 - 2.4e-129 431.1 0.0 3.9e-129 430.4 0.0 1.4 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M16_C PF05193.21 CDJ58293.1 - 1.7e-25 90.1 0.0 3.5e-14 53.2 0.0 3.7 2 2 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDJ58293.1 - 4.9e-17 62.3 0.5 3.6e-15 56.2 0.4 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PEP-utilisers_N PF05524.13 CDJ58293.1 - 1.3 9.3 4.0 11 6.2 0.3 3.7 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal YL1 PF05764.13 CDJ58293.1 - 5.9 6.9 7.3 12 5.9 7.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CDJ58293.1 - 6.4 4.9 6.8 10 4.2 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family AP2 PF00847.20 CDJ58294.1 - 7.1e-06 26.2 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AP2 domain Methyltransf_25 PF13649.6 CDJ58295.1 - 2.9e-08 34.3 0.0 1e-07 32.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ58295.1 - 3.1e-08 33.6 0.1 1.4e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ58295.1 - 3.3e-07 30.3 0.0 7.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ58295.1 - 2e-06 28.4 0.0 1.5e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ58295.1 - 0.00016 22.4 0.0 0.00052 20.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ58295.1 - 0.0046 16.5 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDJ58295.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 CDJ58295.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF755 PF05501.11 CDJ58295.1 - 1.5 9.1 13.2 2.3 8.5 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ58295.1 - 4.9 6.7 13.8 1.4 8.5 5.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_1 PF00036.32 CDJ58297.1 - 7.8e-05 22.0 0.0 0.00081 18.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ58297.1 - 0.00014 21.5 0.0 0.00077 19.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CDJ58297.1 - 0.014 15.8 0.1 0.076 13.5 0.0 2.4 3 1 0 3 3 3 0 EF-hand domain pair HSP90 PF00183.18 CDJ58300.1 - 1.2e-117 394.0 28.0 1.7e-117 393.5 28.0 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDJ58300.1 - 1.3e-16 61.1 0.0 2.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDJ58300.1 - 1.1e-09 38.2 0.1 1.1e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CDJ58300.1 - 0.01 15.8 0.2 0.01 15.8 0.2 1.8 2 0 0 2 2 2 0 Tumour suppressor protein RR_TM4-6 PF06459.12 CDJ58300.1 - 0.066 13.0 15.9 0.11 12.3 15.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CDJ58300.1 - 0.25 11.5 2.0 0.42 10.7 2.0 1.4 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CDJ58300.1 - 0.27 10.4 2.6 0.38 9.9 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 CDJ58300.1 - 0.47 10.5 24.3 0.79 9.8 24.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.16 CDJ58300.1 - 0.52 9.5 7.7 0.82 8.8 7.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GAGA_bind PF06217.12 CDJ58300.1 - 0.59 10.4 9.2 1.1 9.5 9.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 CDJ58300.1 - 1.2 7.9 7.5 1.6 7.4 7.5 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CDJ58300.1 - 1.3 7.2 16.7 1.9 6.7 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 CDJ58300.1 - 2.1 8.7 11.9 3.6 8.0 11.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_circ_N PF07157.12 CDJ58301.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Spt20 PF12090.8 CDJ58302.1 - 0.00027 20.6 98.9 0.017 14.8 8.2 4.2 4 0 0 4 4 4 4 Spt20 family DUF2722 PF10846.8 CDJ58302.1 - 0.0022 17.0 9.0 0.0022 17.0 9.0 4.4 3 1 0 4 4 4 2 Protein of unknown function (DUF2722) ESM4 PF15952.5 CDJ58302.1 - 0.061 13.8 45.6 0.07 13.6 17.9 3.4 3 0 0 3 3 3 0 Enhancer of split M4 family Methyltransf_16 PF10294.9 CDJ58303.1 - 0.093 12.5 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Lysine methyltransferase DUF4616 PF15394.6 CDJ58303.1 - 1 8.3 6.9 1.2 8.0 6.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4616) SARAF PF06682.12 CDJ58304.1 - 0.053 13.2 0.8 0.062 12.9 0.8 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zf-CCCH PF00642.24 CDJ58305.1 - 3e-06 27.0 4.3 5.6e-06 26.1 4.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ58305.1 - 0.0012 18.8 6.6 0.0025 17.8 6.6 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CDJ58305.1 - 0.0014 19.3 0.2 0.0014 19.3 0.2 3.4 3 1 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 CDJ58305.1 - 0.014 15.2 3.8 0.027 14.3 3.8 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Caldesmon PF02029.15 CDJ58305.1 - 0.036 12.8 15.3 0.056 12.2 15.3 1.3 1 0 0 1 1 1 0 Caldesmon Flu_PB1 PF00602.17 CDJ58305.1 - 0.93 7.5 2.7 1.3 7.1 2.7 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 DUF572 PF04502.13 CDJ58305.1 - 7.1 6.2 16.9 0.81 9.3 12.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) LapA_dom PF06305.11 CDJ58306.1 - 0.25 11.2 7.1 3.4 7.6 2.3 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4746 PF15928.5 CDJ58307.1 - 1.5 8.1 5.9 2.7 7.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Borrelia_P83 PF05262.11 CDJ58307.1 - 4.9 5.5 9.7 7 5.0 9.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Menin PF05053.13 CDJ58310.1 - 5.4 5.2 9.1 5.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Menin FAM60A PF15396.6 CDJ58311.1 - 5.7 6.9 5.6 12 5.9 5.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A GREB1 PF15782.5 CDJ58314.1 - 0.043 11.0 47.8 0.063 10.4 47.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ58315.1 - 0.0022 17.7 14.2 0.0022 17.7 14.2 6.3 4 1 0 4 4 4 1 Spt20 family IBN_N PF03810.19 CDJ58316.1 - 0.046 13.6 1.4 0.52 10.3 0.3 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain RRM_1 PF00076.22 CDJ58317.1 - 1.1e-20 73.2 0.0 1.9e-15 56.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ58317.1 - 0.00014 21.9 0.1 0.011 15.9 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 CDJ58317.1 - 0.0098 15.6 0.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain TFIIA PF03153.13 CDJ58319.1 - 0.00073 19.7 31.6 0.00073 19.7 31.6 13.5 3 2 7 11 11 11 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ58319.1 - 0.0015 18.6 8.2 0.0015 18.6 8.2 30.2 21 7 5 26 26 26 6 Unstructured region C-term to UIM in Ataxin3 DUF4179 PF13786.6 CDJ58319.1 - 0.64 10.5 0.0 0.64 10.5 0.0 8.4 6 2 0 6 6 6 0 Domain of unknown function (DUF4179) RuBisCO_large_N PF02788.16 CDJ58320.1 - 0.0017 18.5 0.1 0.0017 18.5 0.1 3.0 3 2 3 6 6 6 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain eIF_4EBP PF05456.11 CDJ58320.1 - 0.66 9.9 4.9 3.5 7.6 4.9 2.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) V_ATPase_I PF01496.19 CDJ58320.1 - 0.82 7.5 3.5 1.2 7.0 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2407 PF10302.9 CDJ58320.1 - 1.4 9.5 3.7 2 9.0 2.4 2.0 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain GREB1 PF15782.5 CDJ58320.1 - 8 3.4 10.0 9.2 3.2 10.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DEAD PF00270.29 CDJ58321.1 - 2.2e-19 69.9 1.4 6.3e-11 42.3 0.1 3.1 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58321.1 - 2.1e-12 47.4 0.0 1.8e-11 44.4 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Macoilin PF09726.9 CDJ58321.1 - 3e-05 22.8 0.1 3e-05 22.8 0.1 2.8 2 0 0 2 2 2 1 Macoilin family ResIII PF04851.15 CDJ58321.1 - 0.0027 17.7 3.7 0.0028 17.7 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ58321.1 - 0.12 12.7 6.9 0.57 10.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain PRAS PF15798.5 CDJ58321.1 - 0.87 10.2 0.0 0.87 10.2 0.0 3.2 3 0 0 3 3 3 0 Proline-rich AKT1 substrate 1 Glyco_trans_4_4 PF13579.6 CDJ58322.1 - 0.014 15.8 0.7 0.02 15.3 0.1 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF5473 PF17567.2 CDJ58322.1 - 0.042 14.1 0.3 0.059 13.7 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5473) Prefoldin PF02996.17 CDJ58323.1 - 2.6e-20 72.5 0.2 3e-20 72.3 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CDJ58323.1 - 0.041 13.8 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit PDEase_I PF00233.19 CDJ58324.1 - 6e-59 199.7 0.4 1.2e-58 198.6 0.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Suf PF05843.14 CDJ58324.1 - 0.019 15.0 3.7 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TMEM154 PF15102.6 CDJ58324.1 - 0.22 11.4 2.7 0.16 11.8 0.5 1.9 2 0 0 2 2 2 0 TMEM154 protein family Trypan_PARP PF05887.11 CDJ58326.1 - 0.015 15.3 5.3 0.015 15.3 5.3 2.5 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Fib_alpha PF08702.10 CDJ58327.1 - 1.1 9.4 6.1 0.14 12.4 1.0 2.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.10 CDJ58329.1 - 0.079 12.8 0.2 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 ASF1_hist_chap PF04729.13 CDJ58330.1 - 1.2e-58 197.4 0.1 3.7e-58 195.8 0.1 1.7 1 1 0 1 1 1 1 ASF1 like histone chaperone TAF4 PF05236.14 CDJ58330.1 - 0.0056 16.5 8.5 0.0056 16.5 8.5 2.4 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF1645 PF07816.11 CDJ58330.1 - 0.0088 16.6 9.9 0.0088 16.6 9.9 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1645) Apt1 PF10351.9 CDJ58330.1 - 0.33 9.8 20.6 0.0083 15.0 12.0 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain BUD22 PF09073.10 CDJ58330.1 - 0.86 8.9 40.8 0.67 9.2 16.4 2.2 2 0 0 2 2 2 0 BUD22 DUF4647 PF15504.6 CDJ58330.1 - 1.6 7.7 12.0 2.7 7.0 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Macoilin PF09726.9 CDJ58330.1 - 4.5 5.7 29.0 0.85 8.1 20.8 2.1 2 0 0 2 2 2 0 Macoilin family PI3K_1B_p101 PF10486.9 CDJ58330.1 - 5.1 4.7 19.3 4.4 5.0 0.4 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NST1 PF13945.6 CDJ58330.1 - 8.1 6.5 27.9 1.6 8.8 22.7 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator tRNA-synt_1c PF00749.21 CDJ58331.1 - 1.5e-54 185.1 0.0 1.2e-32 113.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Utp12 PF04003.12 CDJ58331.1 - 1.3e-13 51.1 2.9 1.3e-13 51.1 2.9 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.32 CDJ58331.1 - 7.5e-09 36.1 6.8 7.9e-07 29.7 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Actin PF00022.19 CDJ58333.1 - 4e-70 236.5 0.0 3e-68 230.3 0.0 2.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDJ58333.1 - 0.026 13.4 1.3 1.8 7.3 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein DNA_mis_repair PF01119.19 CDJ58335.1 - 2.6e-13 49.7 0.0 5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 CDJ58335.1 - 1.2e-08 34.9 3.9 1.2e-08 34.9 3.9 4.5 4 1 1 5 5 5 2 MutL C terminal dimerisation domain SR-25 PF10500.9 CDJ58335.1 - 0.0029 17.3 11.9 0.0029 17.3 11.9 6.2 5 1 1 6 6 6 3 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 CDJ58335.1 - 0.91 8.9 48.0 0.19 11.1 11.0 3.4 3 0 0 3 3 3 0 SDA1 AAA_11 PF13086.6 CDJ58335.1 - 1.8 8.3 46.5 0.036 13.9 9.2 3.6 3 0 0 3 3 3 0 AAA domain TPR_1 PF00515.28 CDJ58336.1 - 4.3e-11 42.1 6.8 8.2e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ58336.1 - 3.6e-10 39.4 8.5 9.3e-09 34.8 2.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 CDJ58336.1 - 1.5e-09 37.9 1.5 1.5e-09 37.9 1.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ58336.1 - 4.6e-09 35.7 8.1 0.00043 20.2 2.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ58336.1 - 1.3e-05 25.0 3.9 0.097 12.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ58336.1 - 0.00033 20.7 0.4 0.00033 20.7 0.4 2.7 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CDJ58336.1 - 0.002 18.8 1.3 0.002 18.8 1.3 3.8 2 2 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ58336.1 - 0.0029 18.1 9.7 0.0029 18.1 9.7 3.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ58336.1 - 0.0043 17.7 10.0 0.0043 17.7 10.0 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat SR-25 PF10500.9 CDJ58336.1 - 0.0047 16.6 37.4 0.0047 16.6 37.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein LCD1 PF09798.9 CDJ58336.1 - 0.0053 15.4 4.8 0.0061 15.1 4.8 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein TPR_17 PF13431.6 CDJ58336.1 - 0.019 15.3 4.5 0.19 12.2 1.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ58336.1 - 0.3 11.2 3.4 2.6 8.3 0.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ58336.1 - 0.68 9.9 9.4 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4667 PF15700.5 CDJ58336.1 - 1.2 9.2 23.9 0.73 9.9 20.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Rapsyn_N PF10579.9 CDJ58336.1 - 1.2 9.3 6.1 3.1 8.0 0.1 2.6 2 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 CDJ58336.1 - 1.6 9.5 9.3 1.1 10.1 0.5 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1635 PF07795.11 CDJ58336.1 - 2.9 7.7 24.3 2.5 7.9 21.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Herpes_pp85 PF04637.12 CDJ58336.1 - 7.3 4.9 15.3 1.7 7.0 11.7 1.7 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Kinesin_assoc PF16183.5 CDJ58336.1 - 7.7 6.6 11.8 1.6 8.9 7.8 1.8 2 0 0 2 2 2 0 Kinesin-associated AF-4 PF05110.13 CDJ58336.1 - 7.8 4.4 38.0 3.1 5.8 34.1 1.8 2 0 0 2 2 2 0 AF-4 proto-oncoprotein WD40 PF00400.32 CDJ58338.1 - 1.1e-12 48.3 7.3 0.00018 22.2 0.3 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ58338.1 - 0.002 18.4 0.0 21 5.5 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ58338.1 - 0.016 13.9 0.8 0.41 9.2 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDJ58338.1 - 0.027 13.2 0.0 0.076 11.7 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like MPS2 PF17060.5 CDJ58338.1 - 0.79 8.9 17.3 2.2 7.5 17.3 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 Rhomboid PF01694.22 CDJ58339.1 - 5.5e-07 29.7 2.7 9.6e-07 28.9 2.5 1.5 1 1 0 1 1 1 1 Rhomboid family DUF4200 PF13863.6 CDJ58341.1 - 1.4e-16 60.9 14.0 1.4e-16 60.9 14.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) HWE_HK PF07536.14 CDJ58341.1 - 0.0094 16.6 0.3 0.038 14.7 0.3 2.1 1 0 0 1 1 1 1 HWE histidine kinase Adeno_E4 PF05385.11 CDJ58341.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Sec2p PF06428.11 CDJ58341.1 - 0.41 10.7 25.0 2.2 8.3 3.3 4.7 2 2 2 4 4 4 0 GDP/GTP exchange factor Sec2p P_C10 PF14974.6 CDJ58341.1 - 1.3 9.2 4.6 8.2 6.6 0.4 3.4 2 1 2 4 4 4 0 Protein C10 Snapin_Pallidin PF14712.6 CDJ58341.1 - 1.4 9.4 18.1 0.99 9.9 6.6 3.0 3 0 0 3 3 3 0 Snapin/Pallidin DUF16 PF01519.16 CDJ58341.1 - 3.8 8.0 23.3 1 9.9 3.5 4.1 2 1 2 4 4 4 0 Protein of unknown function DUF16 ATG16 PF08614.11 CDJ58341.1 - 5.7 7.1 35.2 0.2 11.9 10.1 3.5 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) Cgr1 PF03879.14 CDJ58342.1 - 6.5e-05 23.3 22.3 0.00011 22.5 22.3 1.3 1 0 0 1 1 1 1 Cgr1 family AAA_11 PF13086.6 CDJ58342.1 - 0.051 13.4 7.3 0.072 12.9 7.3 1.4 1 0 0 1 1 1 0 AAA domain DUF4578 PF15147.6 CDJ58342.1 - 0.07 14.0 5.1 0.18 12.7 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) LAP1C PF05609.12 CDJ58342.1 - 1.4 7.9 15.8 0.33 10.0 12.6 1.5 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Kinesin PF00225.23 CDJ58343.1 - 1.7e-67 227.7 0.2 1.7e-67 227.7 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain IMCp PF12314.8 CDJ58343.1 - 0.00073 19.8 8.2 0.0016 18.7 8.2 1.6 1 0 0 1 1 1 1 Inner membrane complex protein LPP20 PF02169.16 CDJ58343.1 - 0.93 9.9 4.2 0.57 10.6 0.5 2.5 2 0 0 2 2 2 0 LPP20 lipoprotein BST2 PF16716.5 CDJ58343.1 - 4.7 7.9 26.5 13 6.5 0.1 3.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF932 PF06067.11 CDJ58343.1 - 5.5 6.7 8.8 21 4.8 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF932) DEAD PF00270.29 CDJ58344.1 - 1.1e-42 145.8 0.0 2.1e-42 144.8 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58344.1 - 1.7e-32 112.0 0.0 1.5e-31 109.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ58344.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ58344.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 CDJ58344.1 - 0.062 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 CDJ58344.1 - 0.069 12.6 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF72 PF01904.18 CDJ58344.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF72 AAA_19 PF13245.6 CDJ58344.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MDMPI_N PF11716.8 CDJ58345.1 - 2.9 8.6 7.1 30 5.3 0.1 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain AF-4 PF05110.13 CDJ58345.1 - 3.1 5.8 39.1 3.7 5.5 39.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ58347.1 - 0.0037 17.6 20.7 0.0037 17.6 20.7 14.5 3 3 4 7 7 7 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ58349.1 - 4.9e-07 29.7 0.0 4.9e-07 29.7 0.0 3.9 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 ANAPC3 PF12895.7 CDJ58349.1 - 0.0005 20.2 0.8 0.0013 18.9 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDJ58349.1 - 0.0049 16.9 6.3 0.037 14.2 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ58349.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.6 CDJ58349.1 - 0.023 15.1 0.1 0.081 13.3 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ58349.1 - 0.029 14.2 1.7 0.072 13.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ58349.1 - 0.07 14.0 0.6 0.07 14.0 0.6 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Rrn6 PF10214.9 CDJ58350.1 - 2.3 6.6 4.7 2.4 6.6 4.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Astro_capsid_N PF03115.14 CDJ58352.1 - 0.075 11.7 0.5 0.07 11.8 0.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Peptidase_A21 PF03566.13 CDJ58352.1 - 0.13 10.5 2.2 0.14 10.4 2.2 1.0 1 0 0 1 1 1 0 Peptidase family A21 G-patch PF01585.23 CDJ58353.1 - 0.00012 21.9 1.5 0.00031 20.6 1.5 1.7 1 0 0 1 1 1 1 G-patch domain zf_CCCH_4 PF18345.1 CDJ58353.1 - 0.074 13.1 0.9 0.18 11.9 0.9 1.7 1 0 0 1 1 1 0 Zinc finger domain PrmA PF06325.13 CDJ58354.1 - 6e-07 29.1 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CDJ58354.1 - 4.6e-06 26.4 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDJ58354.1 - 2.3e-05 25.0 0.1 0.00012 22.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CDJ58354.1 - 0.00015 21.3 0.1 0.00038 20.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDJ58354.1 - 0.00051 19.9 0.8 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ58354.1 - 0.00086 20.0 0.5 0.66 10.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Met_10 PF02475.16 CDJ58354.1 - 0.001 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CDJ58354.1 - 0.0033 18.1 0.0 0.0087 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CDJ58354.1 - 0.022 14.6 0.0 0.087 12.7 0.0 1.8 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 CDJ58354.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_21 PF05050.12 CDJ58354.1 - 0.063 13.3 2.6 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase FkbM domain MMR_HSR1_C PF08438.10 CDJ58355.1 - 1.2e-22 80.6 0.0 3.4e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 GTPase of unknown function C-terminal TFIIA PF03153.13 CDJ58356.1 - 2.6e-10 40.9 52.2 2.6e-10 40.9 52.2 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 CDJ58356.1 - 2.6e-08 33.7 36.8 0.00023 20.7 9.5 2.2 2 0 0 2 2 2 2 SDA1 Presenilin PF01080.17 CDJ58356.1 - 2.6e-07 29.8 28.2 1.4e-05 24.1 21.2 2.2 2 0 0 2 2 2 2 Presenilin Mpp10 PF04006.12 CDJ58356.1 - 2.6e-06 26.2 47.0 0.0012 17.4 9.6 2.1 2 0 0 2 2 2 2 Mpp10 protein CDC45 PF02724.14 CDJ58356.1 - 9.2e-06 24.2 38.7 0.001 17.5 3.2 2.2 2 0 0 2 2 2 2 CDC45-like protein BUD22 PF09073.10 CDJ58356.1 - 1.2e-05 24.8 33.7 0.0021 17.5 5.4 2.3 2 0 0 2 2 2 2 BUD22 Caldesmon PF02029.15 CDJ58356.1 - 0.00018 20.4 18.8 0.00018 20.4 18.8 2.4 2 1 0 2 2 1 1 Caldesmon DUF5427 PF10310.9 CDJ58356.1 - 0.00019 20.5 39.0 0.0039 16.2 26.5 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5427) Zip PF02535.22 CDJ58356.1 - 0.0029 16.9 18.5 0.019 14.2 10.5 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DUF4778 PF16008.5 CDJ58356.1 - 0.0041 17.2 15.4 0.5 10.4 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4778) RR_TM4-6 PF06459.12 CDJ58356.1 - 0.0042 16.9 48.5 0.014 15.2 4.2 2.2 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 CDJ58356.1 - 0.011 16.3 0.3 0.011 16.3 0.3 3.0 3 0 0 3 3 2 0 AAA domain CCSAP PF15748.5 CDJ58356.1 - 0.026 14.7 43.5 0.32 11.1 31.7 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 CDJ58356.1 - 0.04 13.5 44.8 0.052 13.1 32.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CHASE4 PF05228.13 CDJ58356.1 - 0.045 14.0 0.0 0.045 14.0 0.0 2.6 2 1 0 2 2 1 0 CHASE4 domain DUF913 PF06025.12 CDJ58356.1 - 0.07 12.1 0.1 0.07 12.1 0.1 2.7 2 1 0 2 2 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 CDJ58356.1 - 0.086 12.6 40.0 0.17 11.7 9.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CNDH2_C PF16858.5 CDJ58356.1 - 0.11 12.4 33.3 0.15 11.9 22.1 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CAC1F_C PF16885.5 CDJ58356.1 - 0.12 12.0 25.8 0.34 10.5 14.3 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term BAF1_ABF1 PF04684.13 CDJ58356.1 - 0.18 10.8 36.2 1.1 8.2 29.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DNA_pol_phi PF04931.13 CDJ58356.1 - 0.22 9.6 53.8 0.029 12.5 19.8 2.4 3 0 0 3 3 3 0 DNA polymerase phi Neur_chan_memb PF02932.16 CDJ58356.1 - 0.24 11.4 25.1 1 9.3 22.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC27 PF09507.10 CDJ58356.1 - 0.28 10.5 43.1 0.57 9.5 25.0 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 TT_ORF1 PF02956.14 CDJ58356.1 - 0.81 8.3 14.5 0.27 9.9 10.5 1.9 2 0 0 2 2 2 0 TT viral orf 1 DUF4045 PF13254.6 CDJ58356.1 - 0.89 9.1 38.5 0.97 9.0 27.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SARAF PF06682.12 CDJ58356.1 - 1.7 8.2 25.3 1.2 8.7 21.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis LAP1C PF05609.12 CDJ58356.1 - 1.7 7.6 36.9 2 7.4 3.2 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SAPS PF04499.15 CDJ58356.1 - 1.8 7.3 33.5 0.92 8.2 0.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 CDJ58356.1 - 1.8 7.9 53.4 3.7 6.9 17.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 CDJ58356.1 - 2.1 6.5 60.9 2.2 6.4 20.5 2.2 2 0 0 2 2 2 0 Nop14-like family Apt1 PF10351.9 CDJ58356.1 - 2.4 6.9 24.0 1.1 8.0 17.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain TRAP_alpha PF03896.16 CDJ58356.1 - 2.5 7.2 37.8 1.9 7.6 16.7 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4775 PF16001.5 CDJ58356.1 - 3 7.2 47.0 3.5 6.9 28.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) BORG_CEP PF14957.6 CDJ58356.1 - 3.2 8.9 26.8 17 6.6 0.2 2.4 2 0 0 2 2 2 0 Cdc42 effector DAG_kinase_N PF14513.6 CDJ58356.1 - 3.6 7.8 28.3 57 3.9 0.0 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Plasmodium_Vir PF05795.11 CDJ58356.1 - 3.8 6.8 25.1 2.2 7.6 1.5 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SART-1 PF03343.13 CDJ58356.1 - 4.4 5.7 49.8 0.073 11.6 4.8 2.2 2 0 0 2 2 2 0 SART-1 family Sec62 PF03839.16 CDJ58356.1 - 4.7 6.7 31.8 1.8 8.0 21.4 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 FRQ PF09421.10 CDJ58356.1 - 4.7 5.1 30.5 0.27 9.2 20.9 2.0 2 0 0 2 2 2 0 Frequency clock protein PPP4R2 PF09184.11 CDJ58356.1 - 5.8 6.4 49.0 0.84 9.2 15.4 2.2 2 0 0 2 2 2 0 PPP4R2 SLC12 PF03522.15 CDJ58356.1 - 5.9 5.8 36.9 1.3 8.0 27.9 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Velvet PF11754.8 CDJ58356.1 - 6.1 6.7 27.3 3.8 7.4 23.2 2.1 2 0 0 2 2 2 0 Velvet factor PNISR PF15996.5 CDJ58356.1 - 7.1 6.8 56.3 2 8.7 36.9 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR CLN3 PF02487.17 CDJ58356.1 - 9 5.2 26.8 1 8.3 16.7 2.4 2 0 0 2 2 2 0 CLN3 protein Vps16_C PF04840.12 CDJ58357.1 - 6.8e-36 123.9 0.0 2.5e-35 122.1 0.0 1.8 1 1 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CDJ58357.1 - 2.4e-15 56.2 0.1 0.0001 21.2 0.0 3.2 2 1 1 3 3 3 3 Vps16, N-terminal region TFIIA PF03153.13 CDJ58357.1 - 0.041 13.9 11.8 0.27 11.2 2.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CDJ58357.1 - 0.18 11.4 0.9 0.39 10.3 0.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ58357.1 - 5.6 5.8 7.3 0.085 11.8 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ58358.1 - 0.00068 20.0 19.2 0.0013 19.1 8.6 2.2 2 0 0 2 2 2 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ58358.1 - 0.1 12.2 35.1 0.25 11.0 17.3 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein eIF3_subunit PF08597.10 CDJ58358.1 - 0.55 10.1 26.1 0.78 9.6 2.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CD20 PF04103.15 CDJ58358.1 - 0.79 9.8 0.0 0.79 9.8 0.0 2.5 2 1 0 2 2 1 0 CD20-like family Peptidase_S64 PF08192.11 CDJ58358.1 - 1.2 7.6 31.9 1.5 7.2 31.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.10 CDJ58358.1 - 1.3 7.6 45.1 1.7 7.2 45.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GOLD_2 PF13897.6 CDJ58358.1 - 1.7 9.1 15.8 0.22 12.0 4.2 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking GBP_C PF02841.14 CDJ58358.1 - 2.7 7.3 35.5 0.13 11.7 18.8 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain LTV PF04180.14 CDJ58358.1 - 3.3 7.3 30.7 1.5 8.5 17.6 2.1 2 0 0 2 2 2 0 Low temperature viability protein DcuA_DcuB PF03605.14 CDJ58358.1 - 4.3 6.1 8.4 0.43 9.4 1.6 2.0 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Bud13 PF09736.9 CDJ58358.1 - 4.8 7.6 26.9 2.2 8.7 12.8 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex EFTUD2 PF16004.5 CDJ58358.1 - 6.3 7.4 27.1 4 8.0 13.5 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CAC1F_C PF16885.5 CDJ58358.1 - 8.2 6.0 26.4 10 5.7 26.4 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Activator_LAG-3 PF11498.8 CDJ58358.1 - 8.4 5.2 52.1 5.1 5.9 31.4 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RPN2_C PF18004.1 CDJ58358.1 - 9.1 6.2 24.3 2 8.3 12.5 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hamartin PF04388.12 CDJ58358.1 - 9.9 4.7 31.6 12 4.5 31.6 1.0 1 0 0 1 1 1 0 Hamartin protein Med15 PF09606.10 CDJ58359.1 - 0.1 11.3 30.5 0.12 11.0 30.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.19 CDJ58360.1 - 0.027 15.0 7.2 0.027 15.0 7.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NOA36 PF06524.12 CDJ58360.1 - 0.069 12.5 1.5 0.083 12.2 1.5 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CDJ58360.1 - 0.23 11.1 2.4 0.28 10.8 2.4 1.1 1 0 0 1 1 1 0 FAM176 family Se-cys_synth_N PF12390.8 CDJ58360.1 - 0.37 11.1 0.4 0.37 11.1 0.4 1.9 2 0 0 2 2 2 0 Selenocysteine synthase N terminal FXMRP1_C_core PF12235.8 CDJ58360.1 - 1.8 9.2 12.9 2.9 8.5 12.9 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Ribosomal_L11_N PF03946.14 CDJ58362.1 - 6.2e-23 80.4 0.1 1.1e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDJ58362.1 - 2.1e-06 28.1 0.0 3.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF572 PF04502.13 CDJ58363.1 - 1.7e-63 215.3 1.7 1.7e-63 215.3 1.7 1.9 2 1 0 2 2 2 1 Family of unknown function (DUF572) Tox-GHH PF15636.6 CDJ58363.1 - 0.043 13.8 0.5 0.15 12.0 0.5 1.9 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Med3 PF11593.8 CDJ58364.1 - 0.015 14.5 1.5 0.015 14.5 1.5 5.0 2 1 2 4 4 4 0 Mediator complex subunit 3 fungal DUF4045 PF13254.6 CDJ58364.1 - 0.87 9.2 22.9 0.17 11.5 19.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CAC1F_C PF16885.5 CDJ58364.1 - 2.1 8.0 19.5 0.097 12.3 14.4 1.4 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Atrophin-1 PF03154.15 CDJ58364.1 - 3.3 5.9 24.7 4.5 5.4 24.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family SLC12 PF03522.15 CDJ58364.1 - 7.3 5.5 34.4 0.31 10.0 27.5 1.8 2 0 0 2 2 2 0 Solute carrier family 12 Cellulose_synt PF03552.14 CDJ58364.1 - 7.5 4.9 7.5 11 4.3 7.5 1.4 1 0 0 1 1 1 0 Cellulose synthase GAGA_bind PF06217.12 CDJ58364.1 - 7.8 6.7 24.5 1.5 9.1 20.1 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family XRN_M PF17846.1 CDJ58364.1 - 9.6 5.0 27.0 2.2 7.2 22.2 1.8 2 0 0 2 2 2 0 Xrn1 helical domain MID_pPIWI_RE PF18157.1 CDJ58365.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 MID domain of pPIWI_RE SBF2 PF12335.8 CDJ58369.1 - 3.7 7.1 8.3 0.087 12.4 0.8 2.1 2 1 1 3 3 3 0 Myotubularin protein FCH PF00611.23 CDJ58370.1 - 0.093 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Umbravirus_LDM PF04817.12 CDJ58371.1 - 0.088 12.2 3.9 0.16 11.3 3.9 1.3 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Tubulin PF00091.25 CDJ58372.1 - 9.2e-51 172.8 0.0 1.3e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ58372.1 - 2.2e-26 92.5 0.1 2.1e-14 53.7 0.0 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ58372.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ58372.1 - 0.015 14.5 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Tubulin like DRY_EERY PF09750.9 CDJ58373.1 - 1.4 9.2 7.0 0.86 9.9 0.4 2.8 2 0 0 2 2 2 0 Alternative splicing regulator SPX PF03105.19 CDJ58374.1 - 0.0067 16.4 7.2 0.0089 16.0 7.2 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 CDJ58374.1 - 0.011 14.6 6.9 0.014 14.3 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4698 PF15769.5 CDJ58374.1 - 0.032 13.3 8.2 0.047 12.7 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SID-1_RNA_chan PF13965.6 CDJ58374.1 - 0.037 12.5 0.4 0.041 12.3 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4614 PF15391.6 CDJ58374.1 - 0.12 12.3 20.0 0.026 14.6 13.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 CDJ58374.1 - 0.37 9.3 19.4 0.0038 15.9 11.7 1.6 2 0 0 2 2 2 0 Macoilin family Secretin_N_2 PF07655.13 CDJ58374.1 - 0.93 10.1 26.1 1.9 9.1 26.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Miga PF10265.9 CDJ58374.1 - 3.5 6.5 12.3 5.7 5.8 12.3 1.3 1 0 0 1 1 1 0 Mitoguardin Methyltransf_25 PF13649.6 CDJ58375.1 - 1.4e-07 32.1 0.5 5.3e-07 30.3 0.5 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ58375.1 - 3.5e-07 30.3 5.1 3.5e-07 30.3 5.1 3.2 1 1 1 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ58375.1 - 1.7e-06 28.6 0.1 1.7e-06 28.6 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ58375.1 - 5.7e-05 23.8 0.8 5.7e-05 23.8 0.8 3.1 3 2 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CDJ58375.1 - 0.0011 18.6 0.5 0.0028 17.2 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase small domain SpecificRecomb PF10136.9 CDJ58375.1 - 0.0015 16.9 14.2 0.0024 16.3 14.2 1.3 1 0 0 1 1 1 1 Site-specific recombinase Methyltransf_18 PF12847.7 CDJ58375.1 - 0.011 15.7 0.7 0.029 14.3 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ58375.1 - 0.035 13.9 11.1 0.2 11.5 10.5 2.4 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CDJ58375.1 - 0.074 13.4 0.1 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 CDJ58375.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1840 PF08895.11 CDJ58375.1 - 0.22 11.9 10.9 1.1 9.6 6.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Senescence_reg PF04520.13 CDJ58375.1 - 3.6 8.4 21.8 0.025 15.5 7.2 3.1 3 0 0 3 3 3 0 Senescence regulator SUIM_assoc PF16619.5 CDJ58376.1 - 0.015 15.3 1.6 0.015 15.3 1.6 3.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 SurA_N_2 PF13623.6 CDJ58377.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain REC114-like PF15165.6 CDJ58377.1 - 0.17 11.7 3.8 0.2 11.4 3.8 1.0 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Secretin_N_2 PF07655.13 CDJ58377.1 - 0.26 11.9 29.2 0.46 11.0 10.0 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Adeno_PV PF03910.13 CDJ58377.1 - 0.28 9.8 3.7 0.34 9.6 3.7 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV SPX PF03105.19 CDJ58377.1 - 1.1 9.1 10.6 1.3 8.9 10.6 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ58377.1 - 2.7 6.7 13.6 2.8 6.7 13.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DAGK_cat PF00781.24 CDJ58378.1 - 2.1e-11 43.5 0.2 7.6e-08 32.0 0.0 4.5 5 1 1 6 6 6 2 Diacylglycerol kinase catalytic domain RskA PF10099.9 CDJ58378.1 - 0.0013 19.0 1.1 0.0013 19.0 1.1 7.3 2 2 1 4 4 4 1 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ58378.1 - 0.021 15.7 10.2 0.021 15.7 10.2 8.7 5 4 1 6 6 6 0 Domain of unknown function (DUF4834) ER_lumen_recept PF00810.18 CDJ58379.1 - 2.8e-07 31.5 0.4 4.1e-07 30.9 0.4 1.4 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF5417 PF17438.2 CDJ58380.1 - 0.069 13.5 0.0 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5417) Ric8 PF10165.9 CDJ58381.1 - 0.054 12.5 0.8 0.081 12.0 0.8 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Ribosomal_L7Ae PF01248.26 CDJ58383.1 - 1.3e-26 92.2 0.5 1.6e-26 91.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 CDJ58383.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding NB-LRR PF12061.8 CDJ58383.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Late blight resistance protein R1 LPD13 PF18825.1 CDJ58383.1 - 0.091 12.5 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 13 Mannitol_dh_C PF08125.13 CDJ58383.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain eIF-5_eIF-2B PF01873.17 CDJ58384.1 - 9.8e-37 125.4 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Voldacs PF03517.13 CDJ58385.1 - 8.7e-15 55.1 3.5 4.5e-13 49.5 1.5 2.2 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling Sialidase PF02973.16 CDJ58385.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain RMI1_N PF08585.12 CDJ58386.1 - 1.6e-14 54.2 0.1 1.8e-13 50.8 0.1 2.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein WD40 PF00400.32 CDJ58387.1 - 5.8e-09 36.4 2.7 0.0016 19.2 0.0 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CDJ58387.1 - 2e-05 23.8 1.9 0.0047 16.0 0.3 3.0 3 0 0 3 3 3 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 CDJ58387.1 - 0.0014 18.9 0.0 20 5.6 0.0 4.5 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 CDJ58387.1 - 0.027 14.4 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.6 CDJ58387.1 - 0.16 12.5 1.0 0.45 11.1 0.1 2.3 2 0 0 2 2 2 0 PQQ-like domain PPR PF01535.20 CDJ58387.1 - 0.69 10.3 2.4 8.8 6.8 0.0 4.0 6 0 0 6 6 6 0 PPR repeat TPR_6 PF13174.6 CDJ58387.1 - 5.8 7.8 6.2 50 4.8 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 CDJ58388.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF4131 PF13567.6 CDJ58388.1 - 0.073 12.7 2.4 0.12 12.0 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RNase_H_2 PF13482.6 CDJ58390.1 - 1.6 8.7 9.6 12 5.8 0.0 5.7 6 1 1 7 7 7 0 RNase_H superfamily SPEG_u2 PF16650.5 CDJ58390.1 - 2.5 8.3 7.5 0.34 11.1 0.2 3.2 4 0 0 4 4 4 0 Unstructured region on SPEG complex protein AP2 PF00847.20 CDJ58391.1 - 4.6e-07 30.0 5.6 0.0035 17.6 0.0 2.9 3 0 0 3 3 3 2 AP2 domain ACDC PF14733.6 CDJ58391.1 - 0.0022 18.3 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal Got1 PF04178.12 CDJ58392.1 - 4.2e-06 27.2 1.4 5.9e-06 26.7 1.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Ribosomal_L34e PF01199.18 CDJ58393.1 - 4.2e-35 119.9 5.1 4.2e-35 119.9 5.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e zf-3CxxC_2 PF17180.4 CDJ58393.1 - 0.044 14.5 2.1 0.044 14.5 2.1 1.9 2 0 0 2 2 2 0 Zinc-binding domain FtsJ PF01728.19 CDJ58394.1 - 5.4e-55 186.2 0.0 8.1e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CDJ58394.1 - 0.0035 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ58394.1 - 0.012 15.4 0.0 0.31 10.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NSP16 PF06460.12 CDJ58394.1 - 0.034 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 NUDIX_2 PF13869.6 CDJ58395.1 - 6.6e-55 185.6 0.0 9.1e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase SUIM_assoc PF16619.5 CDJ58395.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Capsid-VNN PF11729.8 CDJ58395.1 - 0.21 10.6 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 nodavirus capsid protein WD40 PF00400.32 CDJ58396.1 - 0.012 16.5 2.7 75 4.4 0.2 5.4 4 0 0 4 4 4 0 WD domain, G-beta repeat MCU PF04678.13 CDJ58397.1 - 0.008 16.3 1.1 0.008 16.3 1.1 4.2 3 1 0 3 3 3 1 Mitochondrial calcium uniporter DUF3232 PF11554.8 CDJ58397.1 - 0.15 12.4 1.7 0.35 11.2 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) Ribosomal_L36e PF01158.18 CDJ58398.1 - 1.1e-37 128.2 6.3 1.2e-37 128.0 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.11 CDJ58399.1 - 8.4e-113 376.5 0.3 1.1e-112 376.0 0.3 1.1 1 0 0 1 1 1 1 Bystin DNA_pol_phi PF04931.13 CDJ58399.1 - 2.3 6.2 6.9 3.6 5.6 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF3446 PF11928.8 CDJ58401.1 - 4.7 7.6 22.9 1.5 9.2 11.8 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain MtN3_slv PF03083.16 CDJ58402.1 - 1.3e-16 60.4 2.8 2.4e-10 40.3 0.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Macoilin PF09726.9 CDJ58403.1 - 0.15 10.6 25.3 0.2 10.2 25.3 1.2 1 0 0 1 1 1 0 Macoilin family RRM_Rrp7 PF17799.1 CDJ58403.1 - 0.96 9.2 6.4 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF3402 PF11882.8 CDJ58403.1 - 1.5 7.8 14.6 6.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) SOG2 PF10428.9 CDJ58403.1 - 4.9 6.2 30.5 6.3 5.9 30.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0020 PF01170.18 CDJ58404.1 - 0.013 15.2 0.3 0.033 13.9 0.3 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 EIF4E-T PF10477.9 CDJ58404.1 - 4.1 6.1 16.9 5.9 5.6 16.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E adh_short PF00106.25 CDJ58405.1 - 5.7e-15 55.3 0.0 7.1e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ58405.1 - 4.8e-08 32.8 0.0 5.7e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_60s PF00428.19 CDJ58406.1 - 0.018 15.7 3.4 0.018 15.7 3.4 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein UPF0449 PF15136.6 CDJ58406.1 - 0.031 14.7 1.1 0.031 14.7 1.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Utp11 PF03998.13 CDJ58406.1 - 0.27 11.1 24.3 0.5 10.3 24.3 1.4 1 1 0 1 1 1 0 Utp11 protein FapA PF03961.13 CDJ58407.1 - 5.6 5.4 13.8 1 7.9 8.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A tRNA-synt_1c PF00749.21 CDJ58407.1 - 6.2 5.6 9.1 13 4.5 9.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Thioredoxin PF00085.20 CDJ58408.1 - 3.3e-38 129.8 0.0 1.1e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CDJ58408.1 - 3.4e-11 43.4 0.0 4.6e-07 29.9 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDJ58408.1 - 0.0011 19.4 0.1 0.087 13.3 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ58408.1 - 0.015 15.6 0.0 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 CDJ58408.1 - 0.024 14.6 0.0 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 AhpC/TSA family NAPRTase_C PF17956.1 CDJ58411.1 - 0.088 13.2 0.0 0.097 13.1 0.0 1.1 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain RAP1 PF07218.11 CDJ58412.1 - 0.49 8.6 2.3 0.73 8.0 2.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-RanBP PF00641.18 CDJ58413.1 - 1.9e-06 27.1 5.2 1.9e-06 27.1 5.2 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Dynamin_M PF01031.20 CDJ58415.1 - 4.4e-79 265.7 0.3 6.1e-78 261.9 0.0 2.6 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 CDJ58415.1 - 3e-48 164.0 0.0 9e-48 162.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CDJ58415.1 - 4.8e-22 77.9 0.1 1.5e-21 76.3 0.1 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDJ58415.1 - 0.001 19.2 0.0 0.0029 17.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4726 PF15855.5 CDJ58415.1 - 0.013 15.7 1.3 0.013 15.7 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4726) SipA PF09052.10 CDJ58415.1 - 0.041 13.5 0.3 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 SipA N-terminal domain MPM1 PF17234.2 CDJ58415.1 - 8.3 6.6 7.7 0.13 12.5 0.5 1.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Na_H_Exchanger PF00999.21 CDJ58416.1 - 8.8e-46 156.4 38.2 1.3e-45 155.8 38.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Macoilin PF09726.9 CDJ58416.1 - 0.08 11.5 9.7 0.12 10.9 9.7 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ58416.1 - 0.14 11.0 10.7 0.22 10.3 10.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ58416.1 - 0.14 10.9 5.4 0.1 11.3 2.9 1.9 2 0 0 2 2 2 0 Presenilin Otopetrin PF03189.13 CDJ58416.1 - 0.18 10.6 5.0 0.028 13.2 0.3 2.0 2 0 0 2 2 2 0 Otopetrin PNISR PF15996.5 CDJ58416.1 - 8.2 6.7 11.5 0.8 9.9 5.4 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Cpn10 PF00166.21 CDJ58417.1 - 4.2e-34 116.5 0.0 6.4e-20 71.0 0.1 2.3 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit RAP1 PF07218.11 CDJ58420.1 - 0.64 8.2 4.8 0.84 7.8 4.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF-3c_N PF05470.12 CDJ58422.1 - 1.2 7.4 2.7 1.4 7.1 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.17 CDJ58422.1 - 2.5 6.8 6.6 2.6 6.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ58422.1 - 6.3 5.5 7.8 7 5.4 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LUC7 PF03194.15 CDJ58423.1 - 3.5e-63 213.6 9.4 3.5e-63 213.6 9.4 2.3 1 1 1 2 2 2 1 LUC7 N_terminus NPV_P10 PF05531.12 CDJ58423.1 - 0.14 12.6 2.9 10 6.6 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HSCB_C PF07743.13 CDJ58423.1 - 5 7.7 17.0 0.26 11.8 5.0 3.2 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Cpn60_TCP1 PF00118.24 CDJ58424.1 - 6.1e-53 180.1 1.8 7.4e-53 179.9 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4633 PF15464.6 CDJ58424.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Stomoxyn PF11585.8 CDJ58424.1 - 0.78 9.8 3.6 1.7 8.8 3.6 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Nnf1 PF03980.14 CDJ58425.1 - 0.018 15.4 1.4 0.23 11.8 0.0 3.1 2 0 0 2 2 2 0 Nnf1 FH2 PF02181.23 CDJ58425.1 - 0.041 13.0 0.2 0.075 12.1 0.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Wbp11 PF09429.10 CDJ58427.1 - 2.7e-15 56.5 5.2 3.2e-15 56.3 5.2 1.1 1 0 0 1 1 1 1 WW domain binding protein 11 TFIIA PF03153.13 CDJ58430.1 - 6.4 6.7 18.5 15 5.4 18.6 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dynein_light PF01221.18 CDJ58432.1 - 6.1e-07 29.7 0.1 9.2e-07 29.1 0.0 1.3 2 0 0 2 2 2 1 Dynein light chain type 1 FKBP_C PF00254.28 CDJ58433.1 - 1e-32 112.3 0.0 2.5e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_isomerase PF00160.21 CDJ58433.1 - 7.2e-15 55.6 0.3 9.6e-09 35.7 0.2 2.4 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CDJ58433.1 - 2.2e-11 42.9 14.1 0.0013 18.6 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ58433.1 - 1.1e-09 37.8 10.2 0.001 18.7 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 CDJ58433.1 - 4.9e-08 32.5 10.3 0.066 13.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ58433.1 - 8.6e-07 29.5 4.4 8.4e-06 26.3 1.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ58433.1 - 4.2e-06 26.5 6.6 0.035 14.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ58433.1 - 1.2e-05 25.7 2.4 0.026 15.3 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ58433.1 - 1.9e-05 25.1 3.1 0.0048 17.4 1.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ58433.1 - 0.00036 20.7 0.2 1.2 9.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ58433.1 - 0.0014 18.7 0.2 0.0029 17.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ58433.1 - 0.016 15.5 4.0 0.21 11.9 0.9 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CDJ58433.1 - 0.019 15.1 1.2 0.019 15.1 1.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CDJ58433.1 - 0.034 14.4 2.3 0.07 13.4 0.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Exonuc_VII_S PF02609.16 CDJ58433.1 - 1.1 9.3 4.9 43 4.3 3.0 2.7 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1962 PF09227.10 CDJ58434.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) RIO1 PF01163.22 CDJ58435.1 - 7.7e-47 159.3 0.0 1.2e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDJ58435.1 - 5.8e-33 113.0 0.8 1.8e-32 111.4 0.8 1.9 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CDJ58435.1 - 2e-09 37.8 1.2 0.00096 19.1 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ58435.1 - 1.3e-07 31.2 0.1 0.0029 17.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDJ58435.1 - 0.1 11.4 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1308 PF07000.11 CDJ58435.1 - 0.15 12.0 0.1 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) Ctr PF04145.15 CDJ58436.1 - 2 9.1 18.1 0.93 10.1 4.6 3.2 3 0 0 3 3 3 0 Ctr copper transporter family LMBR1 PF04791.16 CDJ58436.1 - 7 5.4 21.2 1.2 8.0 4.9 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein TFIIA PF03153.13 CDJ58437.1 - 0.0092 16.0 25.1 0.011 15.7 25.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rsc14 PF08586.10 CDJ58437.1 - 0.12 13.2 5.3 0.24 12.2 1.9 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF2407 PF10302.9 CDJ58437.1 - 0.85 10.2 4.5 0.31 11.6 1.1 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Hamartin PF04388.12 CDJ58437.1 - 0.89 8.1 23.5 1.3 7.6 23.5 1.2 1 0 0 1 1 1 0 Hamartin protein Utp14 PF04615.13 CDJ58437.1 - 2.7 6.4 22.2 3.8 6.0 22.2 1.3 1 0 0 1 1 1 0 Utp14 protein SWI-SNF_Ssr4 PF08549.10 CDJ58437.1 - 7.6 5.0 20.3 8.2 4.9 20.3 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Helitron_like_N PF14214.6 CDJ58437.1 - 9.8 6.3 10.2 2.8 8.1 6.6 1.8 1 1 1 2 2 2 0 Helitron helicase-like domain at N-terminus Ecl1 PF12855.7 CDJ58438.1 - 0.00087 20.5 20.4 0.0013 19.9 20.4 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins SR-25 PF10500.9 CDJ58438.1 - 0.097 12.3 20.2 0.14 11.8 20.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ58438.1 - 0.29 11.0 11.2 0.36 10.7 11.2 1.2 1 0 0 1 1 1 0 SPX domain Helicase_C PF00271.31 CDJ58439.1 - 2.4e-14 53.6 0.1 2.4e-14 53.6 0.1 3.7 4 2 2 6 6 6 1 Helicase conserved C-terminal domain PBC PF03792.13 CDJ58440.1 - 0.84 9.4 4.4 3.7 7.3 0.5 2.5 2 0 0 2 2 2 0 PBC domain TipAS PF07739.13 CDJ58440.1 - 8.8 6.9 10.2 1.4 9.5 0.1 3.6 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF1955 PF09205.10 CDJ58441.1 - 1 9.1 4.3 0.7 9.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) ETRAMP PF09716.10 CDJ58442.1 - 0.09 12.9 0.0 0.54 10.4 0.0 2.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4131 PF13567.6 CDJ58442.1 - 0.5 10.0 4.4 0.52 10.0 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3357 PF11837.8 CDJ58442.1 - 8 7.0 7.2 10 6.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Ras PF00071.22 CDJ58443.1 - 5.4e-54 182.2 0.1 9.7e-54 181.3 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ58443.1 - 1.9e-30 105.5 0.0 1.9e-30 105.5 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 CDJ58443.1 - 2.2e-13 50.5 17.3 0.00033 21.4 0.0 8.0 9 0 0 9 9 9 3 WD domain, G-beta repeat Arf PF00025.21 CDJ58443.1 - 5.6e-11 42.2 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ58443.1 - 0.00018 21.5 0.0 0.00083 19.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ANAPC4_WD40 PF12894.7 CDJ58443.1 - 0.021 15.1 0.0 11 6.4 0.0 4.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 CDJ58443.1 - 0.038 13.5 0.0 0.038 13.5 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Rbx_binding PF18113.1 CDJ58443.1 - 0.048 13.4 1.6 0.3 10.9 0.1 3.3 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain zf-C6H2 PF15801.5 CDJ58444.1 - 5.6e-11 42.6 9.8 9.7e-11 41.8 9.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CDJ58444.1 - 0.1 12.7 10.1 0.18 11.9 10.1 1.4 1 0 0 1 1 1 0 MYND finger Apt1 PF10351.9 CDJ58444.1 - 5.6 5.7 12.0 11 4.7 12.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain EF-hand_6 PF13405.6 CDJ58445.1 - 1.1e-09 37.5 0.3 6.5e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain Pkinase PF00069.25 CDJ58445.1 - 2.3e-09 37.0 0.9 2.9e-05 23.6 0.6 2.5 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.32 CDJ58445.1 - 3.7e-09 35.5 1.0 0.00016 21.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDJ58445.1 - 1.1e-06 27.9 3.8 0.00021 20.7 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ58445.1 - 2.5e-05 24.6 0.2 8.5e-05 22.9 0.2 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ58445.1 - 3.7e-05 23.5 1.1 0.0022 17.8 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair PH PF00169.29 CDJ58445.1 - 0.00072 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 CDJ58445.1 - 0.011 15.0 0.5 0.38 10.0 0.4 2.2 1 1 1 2 2 2 0 Protein tyrosine kinase Keratin_B2_2 PF13885.6 CDJ58445.1 - 0.02 14.9 0.4 0.11 12.4 0.4 2.3 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein eIF-1a PF01176.19 CDJ58446.1 - 2.6e-09 36.7 0.0 1.8e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_60s PF00428.19 CDJ58446.1 - 0.63 10.7 15.7 0.096 13.3 8.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein HIP1_clath_bdg PF16515.5 CDJ58447.1 - 0.035 14.7 11.5 0.035 14.7 11.5 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 CDJ58447.1 - 0.076 13.1 3.1 0.15 12.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CDJ58447.1 - 0.082 13.4 5.9 0.11 13.0 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 SOGA PF11365.8 CDJ58447.1 - 0.082 14.0 0.7 0.082 14.0 0.7 3.0 1 1 2 3 3 3 0 Protein SOGA THOC7 PF05615.13 CDJ58447.1 - 0.15 12.4 9.6 0.3 11.3 9.6 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 E2F_CC-MB PF16421.5 CDJ58447.1 - 0.59 10.5 9.0 0.28 11.6 4.5 2.3 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain DUF2730 PF10805.8 CDJ58447.1 - 0.63 10.2 4.5 1.2 9.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Atg14 PF10186.9 CDJ58447.1 - 1.8 7.5 7.5 1.4 7.9 6.6 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 CDJ58447.1 - 2.4 8.3 8.6 0.52 10.5 1.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF4164 PF13747.6 CDJ58447.1 - 3.5 8.0 13.6 0.092 13.0 6.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) CEND1 PF15677.5 CDJ58447.1 - 9.2 6.8 8.2 0.32 11.5 2.5 1.5 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 SpoIIE PF07228.12 CDJ58448.1 - 0.067 13.1 0.0 0.067 13.1 0.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SUIM_assoc PF16619.5 CDJ58449.1 - 0.068 13.2 13.2 0.046 13.8 5.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ58450.1 - 1.1e-22 80.6 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ58450.1 - 2.5e-09 37.4 0.0 7e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SKI PF01202.22 CDJ58450.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 CDJ58450.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_lid_7 PF17867.1 CDJ58451.1 - 0.39 10.9 1.7 17 5.6 0.4 3.3 2 1 1 3 3 3 0 Midasin AAA lid domain DUF4281 PF14108.6 CDJ58452.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) DUF3591 PF12157.8 CDJ58454.1 - 3.4e-12 45.8 0.0 6.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) BSP_II PF05432.11 CDJ58455.1 - 0.076 12.7 15.3 0.53 9.9 9.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Spt5_N PF11942.8 CDJ58455.1 - 0.44 11.6 22.1 2.3 9.3 8.9 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 CDJ58455.1 - 2.4 6.6 12.1 0.071 11.6 3.2 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PRP38_assoc PF12871.7 CDJ58455.1 - 4.1 8.1 20.1 1.2 9.8 4.0 3.3 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RNA_pol_3_Rpc31 PF11705.8 CDJ58455.1 - 8.1 6.6 17.7 37 4.5 0.0 2.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PP2C PF00481.21 CDJ58456.1 - 4.2e-26 92.1 0.0 7.3e-25 88.1 0.0 2.5 1 1 1 2 2 2 1 Protein phosphatase 2C PRKG1_interact PF15898.5 CDJ58456.1 - 0.046 14.6 2.1 0.12 13.3 2.1 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain UPF0225 PF17775.1 CDJ58456.1 - 0.081 13.7 0.1 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 UPF0225 domain Metallophos PF00149.28 CDJ58457.1 - 3.7e-12 47.2 0.1 5.8e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Gypsy PF07253.11 CDJ58458.1 - 0.027 13.0 1.4 0.045 12.3 1.4 1.2 1 0 0 1 1 1 0 Gypsy protein Sec2p PF06428.11 CDJ58458.1 - 0.094 12.7 2.9 0.7 9.9 0.3 2.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF5082 PF16888.5 CDJ58458.1 - 0.1 12.8 2.1 0.29 11.4 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 CDJ58458.1 - 0.21 11.6 0.4 0.69 10.0 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDJ58458.1 - 0.26 10.1 3.8 1.3 7.9 3.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 CDJ58458.1 - 0.63 10.3 5.9 6.5 7.0 4.3 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein TolA_bind_tri PF16331.5 CDJ58458.1 - 2.6 8.2 8.7 0.14 12.3 0.7 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation UPF0242 PF06785.11 CDJ58459.1 - 0.0068 16.5 14.1 0.071 13.2 0.1 3.1 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus CDC14 PF08045.11 CDJ58459.1 - 0.069 12.3 0.0 0.069 12.3 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 14, SIN component Uso1_p115_C PF04871.13 CDJ58459.1 - 3.5 8.0 20.0 0.17 12.3 2.4 4.1 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region AzlD PF05437.12 CDJ58460.1 - 0.014 15.5 0.3 0.048 13.8 0.3 1.8 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) GBP PF02263.19 CDJ58462.1 - 4.5e-19 68.7 0.0 2.4e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDJ58462.1 - 1.9e-12 47.2 16.1 2.8e-12 46.7 16.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DUF881 PF05949.12 CDJ58462.1 - 0.091 12.6 0.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) LMBR1 PF04791.16 CDJ58462.1 - 2.7 6.8 8.2 3.9 6.3 8.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NGP1NT PF08153.12 CDJ58464.1 - 2.8e-35 121.3 0.0 5.7e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CDJ58464.1 - 1.2e-15 57.6 0.0 7e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ58464.1 - 3.1e-07 30.4 0.0 7.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CDJ58464.1 - 3.3e-05 23.5 0.1 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDJ58464.1 - 0.00036 20.1 0.1 0.004 16.7 0.1 2.3 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDJ58464.1 - 0.00058 19.4 0.0 0.91 9.0 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 CDJ58464.1 - 0.12 12.8 0.0 6.5 7.1 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ58464.1 - 0.15 12.1 0.3 7.9 6.5 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Beta-Casp PF10996.8 CDJ58465.1 - 2.3e-21 76.1 0.0 4.2e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CDJ58465.1 - 5.2e-16 58.3 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 CDJ58465.1 - 5.4e-08 32.5 0.0 2.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ58465.1 - 2.5e-06 27.6 0.0 6.5e-05 23.0 0.0 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDJ58465.1 - 0.0046 16.5 0.0 0.081 12.4 0.0 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.24 CDJ58467.1 - 3.7e-32 111.6 1.3 1.5e-31 109.6 1.3 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GP3_package PF16677.5 CDJ58467.1 - 0.044 13.9 0.5 7.2 6.8 0.1 2.4 1 1 0 2 2 2 0 DNA-packaging protein gp3 DNA_primase_lrg PF04104.14 CDJ58467.1 - 0.096 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit BPL_N PF09825.9 CDJ58468.1 - 0.0016 17.6 5.9 0.0016 17.6 5.9 4.5 3 1 0 4 4 4 1 Biotin-protein ligase, N terminal Activator_LAG-3 PF11498.8 CDJ58468.1 - 0.0029 16.7 25.7 0.0029 16.7 25.7 5.9 4 1 0 5 5 5 1 Transcriptional activator LAG-3 MotB_plug PF13677.6 CDJ58469.1 - 0.019 14.6 0.1 2.3 7.9 0.1 5.1 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF3561 PF12084.8 CDJ58469.1 - 0.24 11.4 0.0 5 7.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF4110 PF13422.6 CDJ58470.1 - 1.7e-17 63.3 0.4 1.7e-17 63.3 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 CDJ58470.1 - 0.0053 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain CDC45 PF02724.14 CDJ58470.1 - 2.8 6.1 9.7 3.4 5.9 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MFMR_assoc PF16596.5 CDJ58470.1 - 8.8 6.8 11.8 0.34 11.4 3.9 2.3 2 1 0 2 2 2 0 Disordered region downstream of MFMR RNA_pol_Rpc82 PF05645.13 CDJ58471.1 - 0.02 14.7 0.4 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 OMP_b-brl PF13505.6 CDJ58471.1 - 2.3 8.3 5.1 7 6.7 5.1 1.9 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain RRM_1 PF00076.22 CDJ58472.1 - 3.1e-21 75.0 0.0 4.1e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ58472.1 - 0.00061 19.4 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ58472.1 - 0.059 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif CTP_transf_like PF01467.26 CDJ58473.1 - 0.17 12.1 2.5 0.18 12.0 2.5 1.1 1 0 0 1 1 1 0 Cytidylyltransferase-like Spt20 PF12090.8 CDJ58473.1 - 0.39 10.3 23.5 0.43 10.2 23.5 1.0 1 0 0 1 1 1 0 Spt20 family Methyltrn_RNA_4 PF09936.9 CDJ58473.1 - 1.5 8.6 4.4 1.6 8.6 4.4 1.1 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase CR6_interact PF10147.9 CDJ58473.1 - 1.8 8.2 20.6 18 4.9 20.6 1.9 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Afi1 PF07792.12 CDJ58473.1 - 2.7 8.5 10.5 2.6 8.5 10.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Med15 PF09606.10 CDJ58473.1 - 2.8 6.5 17.5 2.7 6.5 17.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.6 CDJ58473.1 - 2.8 7.6 13.2 3.3 7.4 13.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF2828 PF11443.8 CDJ58473.1 - 3.2 5.7 11.6 3.2 5.7 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RAP1 PF07218.11 CDJ58473.1 - 3.3 5.9 7.7 3.6 5.7 7.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RPN2_C PF18004.1 CDJ58473.1 - 3.5 7.5 17.1 3.9 7.4 17.1 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4834 PF16118.5 CDJ58473.1 - 3.7 8.6 14.6 4.7 8.2 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF913 PF06025.12 CDJ58473.1 - 4.1 6.3 9.7 4.2 6.2 9.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FTZ PF03867.14 CDJ58473.1 - 5 6.6 6.9 5.2 6.5 6.9 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CLN3 PF02487.17 CDJ58473.1 - 6.7 5.7 8.5 6.3 5.7 8.5 1.0 1 0 0 1 1 1 0 CLN3 protein Tim54 PF11711.8 CDJ58473.1 - 6.8 5.4 13.1 6.9 5.3 13.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.16 CDJ58473.1 - 7.7 5.9 9.2 8 5.9 9.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FYDLN_acid PF09538.10 CDJ58473.1 - 8.1 7.2 13.8 9.1 7.0 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 CDJ58473.1 - 9 6.2 20.9 9.7 6.1 20.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ58474.1 - 0.00027 20.1 7.1 0.00027 20.1 7.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RLL PF10036.9 CDJ58474.1 - 0.0032 17.4 16.2 0.0056 16.6 16.2 1.3 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Med15 PF09606.10 CDJ58474.1 - 0.021 13.6 36.1 0.026 13.3 36.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ58474.1 - 0.053 13.6 7.4 0.067 13.2 7.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDJ58474.1 - 0.094 11.0 9.9 0.12 10.7 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Draxin PF15550.6 CDJ58474.1 - 0.1 12.5 10.5 0.14 12.0 10.5 1.3 1 0 0 1 1 1 0 Draxin PAT1 PF09770.9 CDJ58474.1 - 0.12 10.7 23.8 0.14 10.4 23.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ58474.1 - 0.16 11.5 19.6 0.22 11.0 19.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glt_symporter PF03616.14 CDJ58474.1 - 0.2 10.3 0.7 0.3 9.7 0.7 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter PPP4R2 PF09184.11 CDJ58474.1 - 0.21 11.2 8.4 0.32 10.6 8.4 1.3 1 0 0 1 1 1 0 PPP4R2 MMR1 PF08505.10 CDJ58474.1 - 0.24 11.6 17.6 0.37 11.0 17.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein D123 PF07065.14 CDJ58474.1 - 0.3 10.2 8.3 0.48 9.5 8.3 1.3 1 0 0 1 1 1 0 D123 DUF4746 PF15928.5 CDJ58474.1 - 0.43 10.0 8.2 0.8 9.1 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ECH_2 PF16113.5 CDJ58474.1 - 0.88 9.0 14.7 1.5 8.2 14.7 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase SID-1_RNA_chan PF13965.6 CDJ58474.1 - 0.88 7.9 3.1 0.96 7.8 3.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4175 PF13779.6 CDJ58474.1 - 1.1 7.1 38.1 1.6 6.6 38.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CSG2 PF16965.5 CDJ58474.1 - 1.5 7.7 6.0 2.1 7.2 6.0 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Mcm10 PF09332.11 CDJ58474.1 - 1.7 8.0 20.9 2.6 7.4 20.9 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Presenilin PF01080.17 CDJ58474.1 - 1.8 7.2 20.6 2.8 6.6 20.6 1.3 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 CDJ58474.1 - 1.8 8.6 11.5 3.4 7.7 11.5 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.11 CDJ58474.1 - 2.5 7.4 6.8 3.3 7.0 6.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLN3 PF02487.17 CDJ58474.1 - 2.6 7.0 9.3 3.4 6.6 9.3 1.3 1 0 0 1 1 1 0 CLN3 protein DUF966 PF06136.13 CDJ58474.1 - 3.1 7.4 20.2 5.6 6.6 20.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GREB1 PF15782.5 CDJ58474.1 - 3.8 4.5 16.8 4.2 4.3 16.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Folate_carrier PF01770.18 CDJ58474.1 - 4.3 6.0 7.2 6.3 5.4 7.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 CDJ58474.1 - 5 5.3 6.9 6.4 4.9 6.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NST1 PF13945.6 CDJ58474.1 - 5.2 7.1 27.1 8.1 6.5 27.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PCM1_C PF15717.5 CDJ58474.1 - 6.1 5.4 26.5 7.6 5.1 26.5 1.2 1 1 0 1 1 1 0 Pericentriolar material 1 C terminus DUF4638 PF15472.6 CDJ58474.1 - 8.2 6.1 12.7 12 5.5 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF2722 PF10846.8 CDJ58475.1 - 0.0038 16.2 0.5 0.0038 16.2 0.5 7.5 6 1 0 6 6 6 3 Protein of unknown function (DUF2722) DUF202 PF02656.15 CDJ58475.1 - 0.15 12.5 0.1 0.15 12.5 0.1 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Med29 PF11568.8 CDJ58477.1 - 1.8 8.8 28.7 0.21 11.8 14.9 2.6 3 0 0 3 3 3 0 Mediator complex subunit 29 RNA_pol_Rpb4 PF03874.16 CDJ58479.1 - 0.00027 21.3 1.5 0.00061 20.1 0.0 2.3 3 1 0 3 3 3 1 RNA polymerase Rpb4 TmoB PF06234.12 CDJ58479.1 - 0.096 12.8 1.9 10 6.3 0.1 2.5 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) WD40 PF00400.32 CDJ58480.1 - 0.0011 19.8 0.1 1.3e+02 3.7 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat IL15 PF02372.15 CDJ58481.1 - 0.055 13.5 0.2 0.1 12.6 0.1 1.4 1 1 0 1 1 1 0 Interleukin 15 GGDEF_2 PF17853.1 CDJ58482.1 - 0.97 9.7 5.9 17 5.7 1.1 2.9 1 1 1 2 2 2 0 GGDEF-like domain Connexin PF00029.19 CDJ58483.1 - 0.14 11.9 6.3 0.16 11.7 6.3 1.1 1 0 0 1 1 1 0 Connexin DUF4484 PF14831.6 CDJ58483.1 - 0.32 11.0 8.1 0.41 10.7 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Pex14_N PF04695.13 CDJ58483.1 - 0.35 11.5 23.9 0.38 11.4 23.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Afi1 PF07792.12 CDJ58483.1 - 0.54 10.7 12.7 0.63 10.5 12.7 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Mcm10 PF09332.11 CDJ58483.1 - 0.59 9.5 13.0 0.6 9.5 13.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF2370 PF10176.9 CDJ58483.1 - 1.7 8.2 5.6 2 8.0 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) CBP_BcsG PF11658.8 CDJ58483.1 - 1.8 6.9 10.5 1.9 6.8 10.5 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Gastrin PF00918.17 CDJ58483.1 - 1.9 9.5 11.7 2.1 9.3 11.7 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PIP5K PF01504.18 CDJ58483.1 - 2.9 7.0 11.9 3.8 6.6 11.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 CDJ58483.1 - 3.5 5.4 14.3 3.9 5.3 14.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 CDJ58483.1 - 3.5 7.7 12.1 3.7 7.6 12.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF-3_zeta PF05091.12 CDJ58483.1 - 5 6.0 18.7 5.4 5.9 18.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ58483.1 - 5.5 5.6 19.6 5.7 5.6 19.6 1.0 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 CDJ58483.1 - 6.4 5.5 10.2 6.3 5.5 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Kei1 PF08552.11 CDJ58483.1 - 7.3 6.4 7.9 8.3 6.2 7.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FAM60A PF15396.6 CDJ58483.1 - 7.5 6.5 12.1 8.2 6.4 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FemAB PF02388.16 CDJ58483.1 - 8.1 5.2 12.6 8.7 5.1 12.6 1.1 1 0 0 1 1 1 0 FemAB family CSG2 PF16965.5 CDJ58483.1 - 8.5 5.2 6.6 10 5.0 6.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 CDJ58483.1 - 8.8 5.4 7.5 8.8 5.4 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 CDJ58483.1 - 8.9 6.9 6.7 10 6.8 6.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PPL5 PF18168.1 CDJ58483.1 - 9.9 5.3 9.7 12 5.1 9.7 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Mit_KHE1 PF10173.9 CDJ58483.1 - 10 6.2 7.9 14 5.7 7.9 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TMEM51 PF15345.6 CDJ58484.1 - 0.00057 19.8 3.2 0.00057 19.8 3.2 10.3 8 2 3 11 11 11 1 Transmembrane protein 51 SR-25 PF10500.9 CDJ58484.1 - 0.0015 18.2 2.2 0.0015 18.2 2.2 7.8 6 1 1 7 7 7 4 Nuclear RNA-splicing-associated protein TCP PF03634.13 CDJ58484.1 - 0.011 16.2 3.4 0.011 16.2 3.4 9.3 6 3 1 8 8 8 0 TCP family transcription factor Spt20 PF12090.8 CDJ58485.1 - 2.9e-05 23.8 32.9 0.0043 16.7 12.7 2.1 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CDJ58485.1 - 0.0013 17.7 27.6 0.0092 15.0 7.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ58485.1 - 0.0034 18.3 14.8 0.23 12.5 3.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) PEX11 PF05648.14 CDJ58485.1 - 0.01 15.4 2.9 0.14 11.6 0.2 2.1 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1387 PF07139.11 CDJ58485.1 - 0.011 15.5 11.3 0.015 15.0 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 CDJ58485.1 - 0.02 14.9 38.7 0.43 10.5 15.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CDJ58485.1 - 0.022 13.4 14.2 0.03 13.0 14.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RskA PF10099.9 CDJ58485.1 - 0.029 14.6 5.4 0.029 14.6 5.4 3.1 1 1 2 3 3 2 0 Anti-sigma-K factor rskA TERB2 PF15101.6 CDJ58485.1 - 0.066 13.3 17.6 0.099 12.7 4.5 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Rxt3 PF08642.10 CDJ58485.1 - 0.096 13.5 7.0 0.51 11.1 0.7 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 EPL1 PF10513.9 CDJ58485.1 - 0.1 13.0 10.7 1.6 9.1 2.7 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like MAP65_ASE1 PF03999.12 CDJ58485.1 - 0.21 10.2 11.3 0.053 12.2 1.2 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Peroxin-13_N PF04088.13 CDJ58485.1 - 0.35 11.1 9.6 0.32 11.3 1.8 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region LIM_bind PF01803.16 CDJ58485.1 - 0.39 10.2 12.1 0.49 9.9 1.4 2.2 2 0 0 2 2 2 0 LIM-domain binding protein MMR1 PF08505.10 CDJ58485.1 - 0.4 10.9 13.5 1.6 8.9 3.0 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PRC2_HTH_1 PF18118.1 CDJ58485.1 - 0.6 10.9 6.4 6.3 7.7 0.3 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RLL PF10036.9 CDJ58485.1 - 0.66 9.8 21.7 1 9.1 7.0 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF5327 PF17261.2 CDJ58485.1 - 0.71 10.6 21.7 0.99 10.2 4.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) TMEM51 PF15345.6 CDJ58485.1 - 0.87 9.4 19.0 1.6 8.5 4.9 2.3 2 1 0 2 2 2 0 Transmembrane protein 51 MPM1 PF17234.2 CDJ58485.1 - 1.4 9.1 19.9 2.2 8.5 8.6 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 UPF0560 PF10577.9 CDJ58485.1 - 1.8 6.9 20.5 1.1 7.7 5.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EphA2_TM PF14575.6 CDJ58485.1 - 2.3 9.2 7.6 3.7 8.5 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DivIC PF04977.15 CDJ58485.1 - 2.5 7.9 22.5 0.8 9.5 7.2 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF2072 PF09845.9 CDJ58485.1 - 2.9 8.1 7.4 9.2 6.5 1.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Peptidase_S49_N PF08496.10 CDJ58485.1 - 3.8 7.6 13.8 2.6 8.1 1.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CNDH2_M PF16869.5 CDJ58485.1 - 4 8.1 20.4 4.6 7.9 4.9 2.8 2 1 1 3 3 3 0 PF16858 Hid1 PF12722.7 CDJ58485.1 - 4.1 5.4 13.6 5 5.1 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATAD4 PF15321.6 CDJ58485.1 - 4.1 8.8 14.5 6.3 8.2 3.8 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF2681 PF10883.8 CDJ58485.1 - 4.4 7.8 30.0 5.5 7.5 12.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF1764 PF08576.10 CDJ58485.1 - 6.4 7.7 14.1 9.7 7.2 3.2 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RCR PF12273.8 CDJ58485.1 - 7 7.3 13.9 5.6 7.6 4.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3381 PF11861.8 CDJ58485.1 - 7.5 6.3 16.5 3.2 7.5 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF4578 PF15147.6 CDJ58485.1 - 7.8 7.4 19.6 2.1 9.2 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) RAB3GAP2_N PF14655.6 CDJ58485.1 - 8 5.6 14.4 5.8 6.1 1.7 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FliD_N PF02465.18 CDJ58487.1 - 0.011 16.4 3.1 0.011 16.4 3.1 4.4 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus PIP5K PF01504.18 CDJ58487.1 - 1.1 8.5 12.7 1.7 7.8 7.7 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase U1snRNP70_N PF12220.8 CDJ58487.1 - 1.5 9.5 30.3 0.77 10.4 3.8 4.3 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal IF-2 PF11987.8 CDJ58488.1 - 4.2e-18 65.4 0.3 1e-17 64.1 0.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CDJ58488.1 - 1.2e-13 51.2 8.5 2.4e-09 37.5 0.3 4.0 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CDJ58488.1 - 2.8e-13 49.6 0.3 2.8e-13 49.6 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU PF00009.27 CDJ58488.1 - 0.0016 18.0 6.6 0.003 17.1 0.2 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF1635 PF07795.11 CDJ58488.1 - 0.056 13.3 0.1 0.056 13.3 0.1 6.8 4 2 3 7 7 7 0 Protein of unknown function (DUF1635) PI3_PI4_kinase PF00454.27 CDJ58489.1 - 1.7e-08 34.6 0.0 3.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase AAA_lid_6 PF17866.1 CDJ58490.1 - 0.023 14.9 1.0 0.37 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA lid domain GAS PF13851.6 CDJ58490.1 - 0.083 12.2 52.1 0.014 14.7 24.3 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding BRX_N PF13713.6 CDJ58490.1 - 0.1 12.3 2.4 0.15 11.9 0.3 2.4 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain ApoO PF09769.9 CDJ58490.1 - 0.52 10.3 6.0 1.1 9.2 0.1 2.9 1 1 1 2 2 2 0 Apolipoprotein O MPS2 PF17060.5 CDJ58490.1 - 5.7 6.1 26.1 0.61 9.3 2.9 2.8 1 1 2 3 3 3 0 Monopolar spindle protein 2 Peroxin-3 PF04882.12 CDJ58491.1 - 0.00014 21.0 0.0 0.00014 21.0 0.0 4.2 3 1 0 4 4 4 2 Peroxin-3 Mucin PF01456.17 CDJ58491.1 - 0.00061 19.8 4.4 0.00061 19.8 4.4 4.4 4 0 0 4 4 4 2 Mucin-like glycoprotein RskA PF10099.9 CDJ58491.1 - 0.0013 19.0 17.7 0.0026 18.1 4.4 7.5 1 1 5 6 6 6 3 Anti-sigma-K factor rskA Tmemb_9 PF05434.11 CDJ58491.1 - 0.0023 17.8 1.5 0.0023 17.8 1.5 4.3 4 0 0 4 4 4 1 TMEM9 FAM176 PF14851.6 CDJ58491.1 - 0.0061 16.2 1.3 0.0061 16.2 1.3 4.1 4 0 0 4 4 4 2 FAM176 family BUD22 PF09073.10 CDJ58491.1 - 0.0066 15.8 1.7 0.0066 15.8 1.7 3.4 3 1 0 3 3 3 2 BUD22 DUF4834 PF16118.5 CDJ58491.1 - 0.031 15.2 2.7 0.031 15.2 2.7 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) PACT_coil_coil PF10495.9 CDJ58492.1 - 0.11 13.1 0.6 0.28 11.8 0.6 1.7 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PKcGMP_CC PF16808.5 CDJ58493.1 - 4.1e-06 26.5 23.3 0.0011 18.7 2.4 4.5 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 CDJ58493.1 - 1.4e-05 25.3 29.3 0.15 12.5 6.0 4.5 2 2 2 4 4 4 3 Csm1 N-terminal domain Sec2p PF06428.11 CDJ58493.1 - 6.2e-05 22.9 25.0 0.22 11.5 6.4 4.1 3 1 1 4 4 4 3 GDP/GTP exchange factor Sec2p TMF_TATA_bd PF12325.8 CDJ58493.1 - 0.00011 22.3 34.1 0.07 13.4 4.2 4.1 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 CDJ58493.1 - 0.0012 18.5 31.1 0.013 15.1 19.0 2.1 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease FAM76 PF16046.5 CDJ58493.1 - 0.0019 17.6 19.8 0.11 11.8 1.6 3.0 2 1 1 3 3 3 2 FAM76 protein DUF1515 PF07439.11 CDJ58493.1 - 0.002 18.2 8.6 0.21 11.6 0.2 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) TMCO5 PF14992.6 CDJ58493.1 - 0.002 17.7 22.9 0.12 11.9 8.6 3.1 2 1 1 3 3 3 2 TMCO5 family UPF0242 PF06785.11 CDJ58493.1 - 0.0044 17.2 0.6 0.0044 17.2 0.6 3.0 2 1 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus CEP63 PF17045.5 CDJ58493.1 - 0.011 15.7 24.6 0.17 11.8 1.3 2.8 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4407 PF14362.6 CDJ58493.1 - 0.013 14.9 16.1 0.16 11.3 9.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 CDJ58493.1 - 0.019 15.0 8.0 1.5 8.8 0.1 2.9 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CDJ58493.1 - 0.024 14.0 26.6 0.93 8.8 11.1 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 CDJ58493.1 - 0.025 14.6 0.4 0.025 14.6 0.4 3.7 3 1 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 CDJ58493.1 - 0.033 14.0 1.3 0.033 14.0 1.3 4.0 3 1 1 4 4 4 0 Septum formation initiator DUF641 PF04859.12 CDJ58493.1 - 0.035 14.4 24.0 0.096 13.0 0.4 4.0 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 CDJ58493.1 - 0.038 14.3 14.7 0.16 12.3 3.7 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_N PF15905.5 CDJ58493.1 - 0.041 13.3 27.1 0.025 14.1 4.4 3.1 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Med30 PF11315.8 CDJ58493.1 - 0.042 14.1 14.1 4.6 7.4 0.1 3.9 2 1 2 4 4 4 0 Mediator complex subunit 30 DUF2570 PF10828.8 CDJ58493.1 - 0.048 13.5 6.9 3 7.7 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Vps53_N PF04100.12 CDJ58493.1 - 0.086 11.8 12.9 0.92 8.4 2.5 3.0 3 0 0 3 3 3 0 Vps53-like, N-terminal NYD-SP28 PF14772.6 CDJ58493.1 - 0.092 12.8 24.4 0.31 11.1 1.5 3.1 2 1 1 3 3 3 0 Sperm tail FapA PF03961.13 CDJ58493.1 - 0.099 11.2 12.2 0.053 12.1 4.5 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A XPC-binding PF09280.11 CDJ58493.1 - 0.11 12.3 0.2 11 5.8 0.0 2.9 4 0 0 4 4 2 0 XPC-binding domain TPD52 PF04201.15 CDJ58493.1 - 0.13 11.9 0.2 0.13 11.9 0.2 3.5 2 1 1 4 4 4 0 Tumour protein D52 family COG2 PF06148.11 CDJ58493.1 - 0.13 12.3 0.4 0.13 12.3 0.4 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 CDJ58493.1 - 0.16 12.6 19.1 0.23 12.1 1.6 4.1 2 1 2 4 4 4 0 SlyX Spc7 PF08317.11 CDJ58493.1 - 0.16 10.8 29.2 0.91 8.3 11.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein MPS2 PF17060.5 CDJ58493.1 - 0.18 11.0 24.3 0.39 9.9 5.6 3.3 1 1 1 3 3 3 0 Monopolar spindle protein 2 ADIP PF11559.8 CDJ58493.1 - 0.19 11.8 24.5 0.58 10.2 10.2 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 CDJ58493.1 - 0.24 11.9 9.6 6.7 7.3 0.6 3.3 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 CDJ58493.1 - 0.24 11.2 17.8 1.2 8.9 1.7 3.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 Tweety PF04906.13 CDJ58493.1 - 0.34 9.5 1.5 1.6 7.3 0.4 2.0 2 0 0 2 2 2 0 Tweety PhoU PF01895.19 CDJ58493.1 - 0.35 11.4 11.1 11 6.6 2.9 3.5 3 1 0 3 3 3 0 PhoU domain HemX PF04375.14 CDJ58493.1 - 0.35 10.1 20.1 0.16 11.2 1.0 2.6 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase FliJ PF02050.16 CDJ58493.1 - 0.36 11.1 17.4 1.2 9.4 0.2 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein DUF948 PF06103.11 CDJ58493.1 - 0.36 11.1 6.6 1.2 9.4 0.2 2.8 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Sulfatase_C PF14707.6 CDJ58493.1 - 0.37 11.5 4.3 6.7 7.5 0.1 2.7 2 1 1 3 3 2 0 C-terminal region of aryl-sulfatase Vac_Fusion PF02346.16 CDJ58493.1 - 0.39 10.4 3.9 1.2 8.9 0.2 2.8 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Fib_alpha PF08702.10 CDJ58493.1 - 0.4 10.9 7.2 5.1 7.3 0.1 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CDJ58493.1 - 0.51 9.9 20.5 1.1e+02 2.1 20.5 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CDJ58493.1 - 0.53 10.3 34.1 0.66 10.0 2.7 3.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4795 PF16043.5 CDJ58493.1 - 0.65 9.6 19.6 1.4 8.5 19.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 CDJ58493.1 - 0.81 10.1 25.0 5.9 7.3 18.6 2.4 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CDJ58493.1 - 0.89 9.6 10.8 8.2 6.5 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Trans_reg_C PF00486.28 CDJ58493.1 - 1.1 9.3 10.5 4.9 7.3 2.6 3.1 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal ING PF12998.7 CDJ58493.1 - 1.2 9.7 8.3 4.8 7.8 0.4 2.7 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding AAA_13 PF13166.6 CDJ58493.1 - 1.4 7.5 14.4 0.55 8.8 10.0 2.0 1 1 1 2 2 2 0 AAA domain SIMPL PF04402.14 CDJ58493.1 - 1.4 9.4 6.9 2.3 8.7 6.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Glutaredoxin2_C PF04399.13 CDJ58493.1 - 1.5 8.7 6.3 1.2 9.0 0.2 2.9 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain AATF-Che1 PF13339.6 CDJ58493.1 - 1.6 9.4 19.9 22 5.7 0.4 3.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Tropomyosin_1 PF12718.7 CDJ58493.1 - 2.1 8.5 34.4 0.38 10.9 3.2 3.1 2 1 1 3 3 3 0 Tropomyosin like DUF3450 PF11932.8 CDJ58493.1 - 2.1 7.6 22.8 1.8 7.8 7.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Plk4_PB2 PF18409.1 CDJ58493.1 - 3.5 8.4 7.1 53 4.6 1.3 3.0 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 PspA_IM30 PF04012.12 CDJ58493.1 - 4 6.9 29.9 0.39 10.2 1.9 2.7 1 1 1 2 2 2 0 PspA/IM30 family Med9 PF07544.13 CDJ58493.1 - 5.6 7.1 15.7 6.8 6.9 4.8 3.6 3 1 1 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF489 PF04356.12 CDJ58493.1 - 6.2 6.8 12.0 13 5.8 0.5 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF812 PF05667.11 CDJ58493.1 - 6.5 5.5 23.1 80 1.9 23.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CR6_interact PF10147.9 CDJ58493.1 - 8.7 6.0 16.6 0.11 12.2 6.7 2.3 2 1 1 3 3 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 KxDL PF10241.9 CDJ58493.1 - 9.6 6.6 17.1 8 6.8 1.2 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein PMC2NT PF08066.12 CDJ58493.1 - 9.7 7.0 9.8 0.69 10.6 1.5 2.7 3 0 0 3 3 2 0 PMC2NT (NUC016) domain N6_N4_Mtase PF01555.18 CDJ58494.1 - 2.1e-07 30.9 0.0 6.6 6.4 0.0 5.8 3 2 1 4 4 4 1 DNA methylase GATA PF00320.27 CDJ58494.1 - 5.9e-07 29.0 3.8 1.2e-06 28.0 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger RskA PF10099.9 CDJ58495.1 - 1.9e-06 28.3 8.7 0.00016 22.1 1.5 5.2 2 2 1 3 3 3 2 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ58495.1 - 0.00064 18.2 22.0 0.00064 18.2 22.0 3.3 2 1 2 4 4 4 1 Rhoptry-associated protein 1 (RAP-1) Pinin_SDK_memA PF04696.13 CDJ58495.1 - 0.84 9.7 60.8 1.3 9.1 34.8 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SPX PF03105.19 CDJ58496.1 - 7.5e-05 22.8 1.4 7.5e-05 22.8 1.4 5.8 2 2 2 5 5 5 1 SPX domain PRC2_HTH_1 PF18118.1 CDJ58496.1 - 0.12 13.2 0.1 0.12 13.2 0.1 9.3 8 3 0 8 8 8 0 Polycomb repressive complex 2 tri-helical domain Profilin PF00235.19 CDJ58497.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Profilin TFIIA PF03153.13 CDJ58499.1 - 0.0021 18.1 16.8 0.003 17.6 16.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ58499.1 - 0.1 12.2 13.9 0.23 11.1 13.9 1.5 1 0 0 1 1 1 0 Spt20 family DUF3533 PF12051.8 CDJ58499.1 - 0.67 8.8 4.5 1 8.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF3682 PF12446.8 CDJ58499.1 - 0.79 10.2 26.0 0.58 10.6 4.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Pol_alpha_B_N PF08418.10 CDJ58499.1 - 1.7 8.6 7.8 2.9 7.8 7.8 1.5 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2294 PF10057.9 CDJ58499.1 - 2.2 8.4 7.5 27 5.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) TrbI PF03743.14 CDJ58499.1 - 5.8 6.7 6.4 22 4.8 4.3 2.1 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein DHHC PF01529.20 CDJ58500.1 - 6.3e-27 94.3 14.2 6.3e-27 94.3 14.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CDJ58500.1 - 7.5e-19 68.1 1.1 2.9e-09 37.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ58500.1 - 7.6e-18 64.6 1.7 5.2e-06 26.9 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ58500.1 - 1.1e-12 47.9 0.8 6e-07 29.6 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ58500.1 - 1.1e-12 46.9 8.1 5.1e-06 26.4 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CDJ58500.1 - 1.9e-12 47.0 3.3 8.6e-07 29.1 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat DUF3446 PF11928.8 CDJ58500.1 - 0.25 11.7 11.3 0.17 12.2 5.0 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF1772 PF08592.11 CDJ58500.1 - 2.4 8.5 10.1 11 6.3 3.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) SARAF PF06682.12 CDJ58501.1 - 6.2 6.4 23.9 6.7 6.3 23.9 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CHORD PF04968.12 CDJ58502.1 - 5.5e-20 71.9 2.3 5.5e-20 71.9 2.3 1.8 2 0 0 2 2 2 1 CHORD rRNA_processing PF08524.11 CDJ58502.1 - 0.0033 17.5 7.0 0.0068 16.4 7.0 1.4 1 0 0 1 1 1 1 rRNA processing DUF2956 PF11169.8 CDJ58502.1 - 0.0057 16.8 9.8 0.0057 16.8 9.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2956) GREB1 PF15782.5 CDJ58502.1 - 0.014 12.5 22.0 0.017 12.3 22.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CDJ58502.1 - 0.081 12.5 19.1 0.21 11.1 12.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SWI-SNF_Ssr4 PF08549.10 CDJ58502.1 - 0.088 11.4 13.0 0.11 11.1 13.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PBP1_TM PF14812.6 CDJ58502.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.9 CDJ58502.1 - 0.46 8.7 16.3 0.53 8.5 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ58502.1 - 1.1 7.8 18.1 1.6 7.3 18.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sin_N PF04801.13 CDJ58502.1 - 2.4 7.3 23.3 0.74 9.0 20.8 1.4 1 1 0 1 1 1 0 Sin-like protein conserved region Methyltransf_32 PF13679.6 CDJ58502.1 - 2.7 8.0 7.4 2.4 8.1 4.3 2.2 2 0 0 2 2 2 0 Methyltransferase domain Bromodomain PF00439.25 CDJ58504.1 - 2.1e-16 59.7 0.0 3.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3591 PF12157.8 CDJ58504.1 - 1e-08 34.3 0.0 2.2e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CDJ58504.1 - 0.0011 18.8 1.2 0.0029 17.4 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDJ58504.1 - 0.008 16.2 0.4 0.018 15.1 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1487 PF07368.11 CDJ58504.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) zf-CCHC_2 PF13696.6 CDJ58504.1 - 0.59 10.0 1.8 1.1 9.1 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Adaptin_N PF01602.20 CDJ58505.1 - 1.1e-15 57.2 0.9 6.3e-08 31.6 0.2 3.2 1 1 2 3 3 3 3 Adaptin N terminal region B2-adapt-app_C PF09066.10 CDJ58505.1 - 0.008 16.3 3.5 0.063 13.4 0.5 2.4 1 1 1 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Sporozoite_P67 PF05642.11 CDJ58505.1 - 0.083 11.0 18.2 0.23 9.5 18.1 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ58505.1 - 0.11 12.1 11.4 0.17 11.5 11.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Uds1 PF15456.6 CDJ58505.1 - 0.13 12.4 1.4 0.25 11.5 1.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation TraG-D_C PF12696.7 CDJ58505.1 - 0.36 10.8 4.3 0.69 9.9 4.3 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG CDK2AP PF09806.9 CDJ58505.1 - 3.7 7.5 9.5 0.091 12.8 2.9 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RT_RNaseH_2 PF17919.1 CDJ58506.1 - 2.5e-28 98.1 0.0 6.4e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ58506.1 - 1.1e-24 86.7 0.0 2.1e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDJ58506.1 - 4.7e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain DUF1542 PF07564.11 CDJ58507.1 - 0.067 13.3 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) VWA PF00092.28 CDJ58508.1 - 1.2e-30 107.0 0.0 1.7e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CDJ58508.1 - 1.6e-24 85.9 67.8 2.4e-09 37.3 1.8 7.2 6 1 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.6 CDJ58508.1 - 9e-14 52.0 0.0 1.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CDJ58508.1 - 0.0049 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CDJ58508.1 - 0.032 14.3 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF3273 PF11677.8 CDJ58509.1 - 1.1e-57 195.4 0.8 1.3e-57 195.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) TPR_14 PF13428.6 CDJ58511.1 - 0.0022 18.7 0.3 0.0034 18.1 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ58511.1 - 0.063 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ58511.1 - 0.22 12.3 2.0 0.37 11.5 2.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Aldedh PF00171.22 CDJ58512.1 - 8.8e-06 24.5 0.0 0.036 12.6 0.1 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family Unstab_antitox PF09720.10 CDJ58512.1 - 0.072 13.1 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 Putative addiction module component PaRep2b PF07775.11 CDJ58512.1 - 0.26 9.7 0.0 0.36 9.2 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein UMP1 PF05348.11 CDJ58513.1 - 1.3e-09 38.3 0.1 2.5e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 AAA_lid_3 PF17862.1 CDJ58514.1 - 8.1e-13 48.0 0.5 1e-12 47.6 0.5 1.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ58514.1 - 0.013 15.9 0.1 0.026 15.0 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) WES_acyltransf PF03007.16 CDJ58515.1 - 0.00017 21.5 0.0 0.00079 19.3 0.0 2.1 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-ribbon_3 PF13248.6 CDJ58515.1 - 0.059 12.8 1.0 0.16 11.5 1.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF4588 PF15251.6 CDJ58516.1 - 0.042 13.6 0.2 0.079 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) SRC-1 PF08832.10 CDJ58517.1 - 4 8.5 10.1 8.9 7.4 4.6 2.3 2 0 0 2 2 2 0 Steroid receptor coactivator Macoilin PF09726.9 CDJ58517.1 - 6.4 5.2 9.8 7.2 5.0 9.8 1.1 1 0 0 1 1 1 0 Macoilin family CDC14 PF08045.11 CDJ58520.1 - 0.076 12.1 0.4 0.096 11.8 0.3 1.3 1 1 0 1 1 1 0 Cell division control protein 14, SIN component VID27 PF08553.10 CDJ58522.1 - 2.6e-18 66.2 1.1 1.1e-08 34.5 0.2 2.0 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain WD40 PF00400.32 CDJ58522.1 - 0.038 14.9 0.1 1.1 10.2 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat CARDB PF07705.11 CDJ58523.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 CARDB HTH_3 PF01381.22 CDJ58525.1 - 8e-15 54.6 0.2 1.2e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CDJ58525.1 - 2.6e-08 34.1 0.0 3.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CDJ58525.1 - 2e-07 30.9 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 CDJ58525.1 - 0.0038 17.6 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 CDJ58525.1 - 0.0045 16.7 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 CDJ58525.1 - 0.011 15.7 0.3 0.028 14.3 0.2 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 CDJ58525.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pou PF00157.17 CDJ58525.1 - 0.05 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Transketolase_N PF00456.21 CDJ58526.1 - 5.4e-90 301.7 0.0 1.1e-89 300.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDJ58526.1 - 1.1e-36 126.2 0.0 1.8e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ58526.1 - 0.001 18.9 0.0 0.0029 17.5 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain PAM2 PF07145.15 CDJ58529.1 - 0.16 11.7 8.3 0.041 13.6 3.3 2.4 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SAWADEE PF16719.5 CDJ58530.1 - 0.01 15.9 0.1 0.062 13.3 0.0 2.4 2 1 1 3 3 3 0 SAWADEE domain XRN_M PF17846.1 CDJ58530.1 - 0.027 13.4 8.2 0.017 14.1 2.7 2.1 2 0 0 2 2 2 0 Xrn1 helical domain DDHD PF02862.17 CDJ58530.1 - 0.65 10.1 9.3 1.2 9.3 2.8 2.2 2 0 0 2 2 2 0 DDHD domain zf-CpG_bind_C PF12269.8 CDJ58530.1 - 7.3 6.3 11.8 4.1 7.1 0.6 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain BAF1_ABF1 PF04684.13 CDJ58530.1 - 7.7 5.4 15.9 2.9 6.8 9.9 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.25 CDJ58531.1 - 1.1e-23 84.0 0.0 1.5e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58531.1 - 1.5e-14 53.9 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ58531.1 - 6.8e-08 31.7 0.0 9.1e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ58531.1 - 0.0022 18.0 0.2 0.0022 18.0 0.2 4.0 3 2 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 CDJ58531.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PepSY_2 PF13670.6 CDJ58531.1 - 5.5 7.1 9.1 34 4.5 8.7 2.5 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain BSD PF03909.17 CDJ58534.1 - 0.015 15.3 0.9 11 6.1 0.2 3.3 2 1 0 2 2 2 0 BSD domain DFRP_C PF16543.5 CDJ58534.1 - 5.9 7.5 7.7 50 4.5 0.1 3.6 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 PLDc_2 PF13091.6 CDJ58535.1 - 2e-07 31.0 0.0 0.0033 17.3 0.0 3.3 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDJ58535.1 - 0.0023 18.0 3.2 0.71 10.2 0.0 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif FlpD PF02662.16 CDJ58535.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit MyTH4 PF00784.17 CDJ58536.1 - 2.6e-13 50.4 4.6 3.6e-13 49.9 1.4 2.6 3 0 0 3 3 3 1 MyTH4 domain DegS PF05384.11 CDJ58536.1 - 0.0024 17.4 2.6 4.4 6.8 0.6 3.7 3 0 0 3 3 3 2 Sensor protein DegS Peptidase_S46 PF10459.9 CDJ58536.1 - 0.0032 16.2 2.4 0.0048 15.6 2.4 1.2 1 0 0 1 1 1 1 Peptidase S46 PLU-1 PF08429.11 CDJ58536.1 - 0.033 13.4 3.3 0.065 12.4 2.3 2.0 2 0 0 2 2 2 0 PLU-1-like protein DUF948 PF06103.11 CDJ58536.1 - 0.14 12.4 1.0 0.4 11.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Presenilin PF01080.17 CDJ58537.1 - 0.31 9.8 3.1 0.28 9.9 1.7 1.6 2 0 0 2 2 2 0 Presenilin MnhB PF04039.13 CDJ58537.1 - 0.44 10.9 2.6 1.2 9.5 2.6 1.6 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF2353 PF09789.9 CDJ58538.1 - 0.024 14.0 4.1 0.048 13.0 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Baculo_F PF12259.8 CDJ58538.1 - 0.27 9.7 1.6 0.57 8.6 1.0 1.7 2 0 0 2 2 2 0 Baculovirus F protein DUF3037 PF11236.8 CDJ58538.1 - 2.4 8.6 5.0 2.4 8.6 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) YabA PF06156.13 CDJ58538.1 - 6 7.6 7.3 63 4.3 5.9 3.0 2 1 0 2 2 2 0 Initiation control protein YabA Diphthami_syn_2 PF01902.17 CDJ58541.1 - 1.9e-25 89.6 0.0 2.5e-23 82.7 0.0 2.7 1 1 0 1 1 1 1 Diphthamide synthase AAA PF00004.29 CDJ58542.1 - 4.4e-40 137.2 0.0 1.1e-39 135.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CDJ58542.1 - 2.5e-16 59.5 0.3 2.5e-16 59.5 0.3 1.7 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 CDJ58542.1 - 6.7e-15 54.8 1.0 1.5e-14 53.7 1.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CDJ58542.1 - 1.3e-08 34.5 0.0 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 CDJ58542.1 - 6.1e-06 26.1 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ58542.1 - 4.2e-05 23.4 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CDJ58542.1 - 0.00016 22.1 1.5 0.3 11.4 0.0 3.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CDJ58542.1 - 0.00019 21.4 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ58542.1 - 0.00023 21.4 0.5 0.011 16.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ58542.1 - 0.00028 21.0 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDJ58542.1 - 0.00062 19.4 1.5 1 8.9 0.3 3.4 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.14 CDJ58542.1 - 0.00065 19.7 0.4 0.0055 16.7 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDJ58542.1 - 0.00094 19.3 0.1 0.0023 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 CDJ58542.1 - 0.0099 15.3 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 1 PhoH-like protein TPR_12 PF13424.6 CDJ58542.1 - 0.012 15.9 3.1 0.026 14.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_30 PF13604.6 CDJ58542.1 - 0.014 15.1 0.3 0.071 12.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ58542.1 - 0.015 15.9 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ58542.1 - 0.015 15.5 0.1 0.07 13.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDJ58542.1 - 0.025 15.0 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ58542.1 - 0.075 12.9 0.1 5.6 6.9 0.0 3.0 1 1 1 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 CDJ58542.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 CDJ58542.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PND PF17949.1 CDJ58542.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 FANCM pseudonuclease domain RNA_helicase PF00910.22 CDJ58542.1 - 0.24 11.8 0.0 0.59 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TPR_2 PF07719.17 CDJ58542.1 - 1 9.7 3.9 6.1 7.2 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 CDJ58543.1 - 6.7e-11 42.1 3.6 9.7e-11 41.6 0.0 3.0 3 1 0 3 3 3 1 DnaJ domain PNISR PF15996.5 CDJ58547.1 - 0.0099 16.2 2.5 0.0099 16.2 2.5 2.9 1 1 2 3 3 3 2 Arginine/serine-rich protein PNISR FHA PF00498.26 CDJ58548.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain ACP_syn_III_C PF08541.10 CDJ58550.1 - 7.1e-21 74.2 3.9 3.9e-11 43.0 0.2 2.9 1 1 2 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 CDJ58550.1 - 8.6e-16 57.6 0.0 8.6e-16 57.6 0.0 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.15 CDJ58550.1 - 0.027 14.5 0.3 0.093 12.7 0.1 1.8 1 1 1 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain Macoilin PF09726.9 CDJ58551.1 - 2.1e-05 23.3 2.0 2.1e-05 23.3 2.0 1.9 2 0 0 2 2 1 1 Macoilin family BCDHK_Adom3 PF10436.9 CDJ58551.1 - 0.00034 20.5 0.0 0.00034 20.5 0.0 2.1 3 0 0 3 3 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TAF4 PF05236.14 CDJ58551.1 - 0.0011 18.7 10.9 0.0011 18.7 10.9 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Paf1 PF03985.13 CDJ58551.1 - 0.003 16.6 14.2 0.003 16.6 14.2 1.9 2 0 0 2 2 2 1 Paf1 Sporozoite_P67 PF05642.11 CDJ58551.1 - 0.0035 15.5 8.7 0.0054 14.9 8.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF2052 PF09747.9 CDJ58551.1 - 0.0064 16.6 11.7 0.0064 16.6 11.7 2.1 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Fmp27 PF10344.9 CDJ58551.1 - 0.083 11.0 4.8 0.13 10.3 4.8 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DNA_pol_phi PF04931.13 CDJ58551.1 - 0.086 10.9 11.9 0.14 10.3 11.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Spt20 PF12090.8 CDJ58551.1 - 0.13 11.9 41.8 0.062 12.9 15.9 2.2 2 0 0 2 2 2 0 Spt20 family Med19 PF10278.9 CDJ58551.1 - 0.19 11.7 8.8 0.089 12.7 2.2 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF572 PF04502.13 CDJ58551.1 - 0.54 9.8 14.5 0.16 11.6 10.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIF_alpha PF05793.12 CDJ58551.1 - 0.66 8.5 13.4 1.1 7.8 13.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CPSF100_C PF13299.6 CDJ58551.1 - 0.78 9.9 11.5 0.69 10.1 7.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SART-1 PF03343.13 CDJ58551.1 - 1.1 7.7 18.8 0.99 7.9 12.4 2.0 2 0 0 2 2 2 0 SART-1 family Slu7 PF11708.8 CDJ58551.1 - 1.3 8.7 17.7 8 6.1 14.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor TERB2 PF15101.6 CDJ58551.1 - 1.4 8.9 19.9 0.26 11.3 7.1 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SpoIIIAH PF12685.7 CDJ58551.1 - 1.5 8.6 14.7 0.078 12.8 8.1 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein EPL1 PF10513.9 CDJ58551.1 - 1.5 9.2 14.5 4.6 7.6 8.8 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Afi1 PF07792.12 CDJ58551.1 - 1.6 9.2 14.8 1.1 9.8 9.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 CDJ58551.1 - 1.7 6.8 18.9 0.6 8.3 14.8 1.9 2 0 0 2 2 2 0 CDC45-like protein DUF1645 PF07816.11 CDJ58551.1 - 1.8 9.1 19.0 0.99 10.0 15.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) MPM1 PF17234.2 CDJ58551.1 - 1.8 8.8 17.3 0.46 10.7 6.6 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 SpoIIP PF07454.11 CDJ58551.1 - 1.9 7.9 16.2 0.29 10.6 8.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ58551.1 - 2.2 6.9 12.9 0.35 9.5 6.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Mif2_N PF15624.6 CDJ58551.1 - 3 8.6 15.6 2.1 9.1 12.2 2.1 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Rtf2 PF04641.12 CDJ58551.1 - 5.8 6.2 11.7 0.32 10.3 5.2 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger DUF936 PF06075.12 CDJ58551.1 - 6.3 5.6 18.7 0.4 9.5 13.8 1.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) YABBY PF04690.13 CDJ58551.1 - 6.8 7.2 8.9 9.4 6.8 3.7 2.3 2 0 0 2 2 2 0 YABBY protein Chorion_2 PF03964.15 CDJ58551.1 - 7.1 7.5 23.1 0.077 13.8 8.6 2.5 1 1 1 2 2 2 0 Chorion family 2 RXT2_N PF08595.11 CDJ58551.1 - 7.3 6.6 14.2 0.94 9.5 9.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF913 PF06025.12 CDJ58551.1 - 7.9 5.3 11.1 1.3 8.0 6.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RPA43_OB PF17875.1 CDJ58551.1 - 8.1 7.1 12.4 36 5.0 7.0 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Roughex PF06020.11 CDJ58551.1 - 8.9 5.3 28.0 0.15 11.1 15.1 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Methyltransf_11 PF08241.12 CDJ58552.1 - 3.3e-22 78.9 0.0 2.1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ58552.1 - 3.5e-22 78.9 0.1 1.9e-21 76.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ58552.1 - 1.1e-19 70.9 0.0 1.9e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ58552.1 - 1.1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDJ58552.1 - 2e-13 50.3 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CDJ58552.1 - 7.5e-12 45.1 0.0 2e-09 37.2 0.0 2.3 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDJ58552.1 - 4.7e-11 43.3 0.0 1.4e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDJ58552.1 - 1.7e-06 27.7 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 CDJ58552.1 - 0.00043 20.4 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 CDJ58552.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 CDJ58552.1 - 0.0011 18.8 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 CDJ58552.1 - 0.0012 18.3 0.0 0.019 14.5 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TPMT PF05724.11 CDJ58552.1 - 0.0014 18.3 0.0 0.0064 16.2 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 CDJ58552.1 - 0.0019 17.8 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_PK PF05891.12 CDJ58552.1 - 0.0054 16.3 0.0 0.04 13.4 0.0 2.0 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.20 CDJ58552.1 - 0.0081 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 CDJ58552.1 - 0.0092 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 CDJ58552.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 CDJ58552.1 - 0.033 14.2 0.1 0.096 12.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 CDJ58552.1 - 0.058 12.8 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Str_synth PF03088.16 CDJ58554.1 - 7.5e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 CDJ58554.1 - 0.00044 19.9 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF2722 PF10846.8 CDJ58555.1 - 0.00042 19.4 7.6 0.00042 19.4 7.6 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) DUF5312 PF17239.2 CDJ58555.1 - 2.9 6.1 14.8 0.16 10.3 1.8 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5312) MFS_1 PF07690.16 CDJ58558.1 - 9.2e-21 74.1 31.7 9.2e-21 74.1 31.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ58558.1 - 0.00058 18.8 9.5 0.00058 18.8 9.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 CDJ58558.1 - 1 7.6 13.5 0.013 13.9 1.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PSS PF03034.15 CDJ58559.1 - 6.2e-74 249.2 14.9 8.9e-74 248.7 14.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF962 PF06127.11 CDJ58559.1 - 0.028 14.5 0.0 1.9 8.6 0.0 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF1635 PF07795.11 CDJ58559.1 - 0.16 11.8 3.8 0.26 11.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) NIF PF03031.18 CDJ58561.1 - 3.7e-15 56.0 0.0 5.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LAP1C PF05609.12 CDJ58561.1 - 2.5 7.1 11.9 3.6 6.6 11.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Porin_3 PF01459.22 CDJ58562.1 - 8.6e-21 74.6 0.0 1.5e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic porin DUF3645 PF12359.8 CDJ58562.1 - 0.055 12.9 0.1 0.055 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3645) DUF444 PF04285.12 CDJ58564.1 - 0.13 11.3 0.6 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF444) RRM_1 PF00076.22 CDJ58565.1 - 1.5e-18 66.3 0.0 2.2e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ58565.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RhoGEF67_u2 PF16614.5 CDJ58565.1 - 0.073 13.1 0.2 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Pkinase PF00069.25 CDJ58566.1 - 6.2e-69 232.3 0.0 7.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58566.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ58566.1 - 4.1e-06 26.3 0.0 2.8e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ58566.1 - 7.1e-06 25.5 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ58566.1 - 0.00047 20.1 0.0 0.55 10.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cytokin-bind PF09265.10 CDJ58566.1 - 0.063 12.6 0.0 0.2 11.0 0.0 1.8 3 0 0 3 3 3 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TFIIA PF03153.13 CDJ58567.1 - 0.016 15.3 13.2 0.014 15.4 9.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5349 PF17298.2 CDJ58567.1 - 0.93 9.2 10.9 0.21 11.3 6.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5349) Spt20 PF12090.8 CDJ58567.1 - 0.94 9.0 15.4 1.9 8.0 15.4 1.4 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CDJ58567.1 - 3.2 6.7 12.0 0.067 12.3 5.1 1.7 2 0 0 2 2 2 0 Drosophila roughex protein BAP PF06639.11 CDJ58571.1 - 0.0027 18.0 0.2 0.004 17.5 0.2 1.3 1 0 0 1 1 1 1 Basal layer antifungal peptide (BAP) DUF4148 PF13663.6 CDJ58571.1 - 1.2 9.4 11.0 4.8 7.4 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SR-25 PF10500.9 CDJ58571.1 - 1.8 8.1 12.7 2 8.0 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 CDJ58571.1 - 6 4.8 8.7 5.8 4.9 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen K_channel_TID PF07941.11 CDJ58571.1 - 6.4 7.3 17.5 1.2 9.6 2.7 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4680 PF15730.5 CDJ58571.1 - 8.7 6.7 11.5 3.9 7.8 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4680) OTCace PF00185.24 CDJ58572.1 - 0.015 15.4 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SR-25 PF10500.9 CDJ58572.1 - 0.39 10.3 5.6 0.83 9.2 5.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4724 PF15852.5 CDJ58572.1 - 0.83 10.2 3.1 0.76 10.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) Dehydrin PF00257.19 CDJ58572.1 - 7.1 7.2 13.0 0.12 13.0 4.8 2.0 2 1 0 2 2 2 0 Dehydrin zf-ZPR1 PF03367.13 CDJ58573.1 - 1.7e-33 115.7 0.0 1.7e-33 115.7 0.0 3.9 4 0 0 4 4 2 1 ZPR1 zinc-finger domain BRF1 PF07741.13 CDJ58573.1 - 0.0018 18.6 5.2 0.0018 18.6 5.2 3.3 2 1 0 2 2 1 1 Brf1-like TBP-binding domain U1snRNP70_N PF12220.8 CDJ58573.1 - 0.004 17.8 1.7 0.004 17.8 1.7 2.7 2 1 0 2 2 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SDA1 PF05285.12 CDJ58573.1 - 0.017 14.5 43.0 0.15 11.4 10.3 2.3 2 0 0 2 2 2 0 SDA1 DUF572 PF04502.13 CDJ58573.1 - 0.018 14.7 27.1 0.48 10.0 1.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Raftlin PF15250.6 CDJ58573.1 - 0.021 13.6 25.8 0.042 12.6 17.8 2.3 2 0 0 2 2 2 0 Raftlin Presenilin PF01080.17 CDJ58573.1 - 0.032 13.0 32.1 0.27 9.9 1.0 2.2 2 0 0 2 2 2 0 Presenilin Corona_nucleoca PF00937.18 CDJ58573.1 - 0.25 10.3 18.3 0.42 9.6 18.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Activator_LAG-3 PF11498.8 CDJ58573.1 - 0.26 10.2 29.8 0.47 9.4 29.8 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Mpp10 PF04006.12 CDJ58573.1 - 0.26 9.7 43.0 0.26 9.7 27.2 2.1 2 0 0 2 2 2 0 Mpp10 protein CCSAP PF15748.5 CDJ58573.1 - 0.3 11.2 35.8 1.6 8.9 25.0 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Velvet PF11754.8 CDJ58573.1 - 0.31 10.9 18.1 0.1 12.5 13.6 2.0 2 0 0 2 2 2 0 Velvet factor SR-25 PF10500.9 CDJ58573.1 - 0.43 10.2 49.8 0.47 10.0 7.8 2.6 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CDJ58573.1 - 0.45 8.7 33.1 0.85 7.8 21.3 2.1 2 0 0 2 2 2 0 CDC45-like protein zf-ribbon_3 PF13248.6 CDJ58573.1 - 0.61 9.6 3.1 13 5.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain BAF1_ABF1 PF04684.13 CDJ58573.1 - 1.3 8.0 37.9 0.63 9.0 8.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Rtf2 PF04641.12 CDJ58573.1 - 1.4 8.2 31.1 0.37 10.1 6.4 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4045 PF13254.6 CDJ58573.1 - 4.6 6.8 30.8 1.5 8.4 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) TCP PF03634.13 CDJ58573.1 - 4.7 7.8 34.4 3.3 8.3 0.7 2.4 2 0 0 2 2 2 0 TCP family transcription factor Neur_chan_memb PF02932.16 CDJ58573.1 - 4.9 7.1 20.7 16 5.4 0.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LptF_LptG PF03739.14 CDJ58573.1 - 5 5.9 6.7 1.8 7.3 4.5 1.6 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG eIF-3_zeta PF05091.12 CDJ58573.1 - 5.8 5.8 27.0 14 4.5 22.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SLC12 PF03522.15 CDJ58573.1 - 7.5 5.5 30.4 3.2 6.7 0.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Suf PF05843.14 CDJ58573.1 - 8.7 6.2 29.5 1.2 9.1 22.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 CDJ58573.1 - 9.1 5.1 20.8 7.2 5.5 12.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 CDJ58573.1 - 9.1 5.8 31.9 4.5 6.8 3.7 2.3 2 0 0 2 2 2 0 PPP4R2 Topoisom_I_N PF02919.15 CDJ58573.1 - 10 5.6 18.9 0.089 12.3 3.0 2.4 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment HemY_N PF07219.13 CDJ58574.1 - 0.00084 19.5 2.2 0.00084 19.5 2.2 3.8 3 1 0 3 3 3 1 HemY protein N-terminus DUF5345 PF17280.2 CDJ58574.1 - 0.0066 16.4 4.4 0.0066 16.4 4.4 4.3 4 1 0 4 4 4 1 Family of unknown function (DUF5345) Collagen PF01391.18 CDJ58574.1 - 2.1 8.1 16.7 0.16 11.8 11.2 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Caldesmon PF02029.15 CDJ58575.1 - 1.2 7.9 76.0 1.5 7.5 76.0 1.0 1 0 0 1 1 1 0 Caldesmon DUF966 PF06136.13 CDJ58575.1 - 1.5 8.5 48.5 2 8.0 48.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) AMA-1 PF02430.15 CDJ58576.1 - 1.6e-13 50.4 3.9 3.6e-09 36.1 0.3 2.1 1 1 1 2 2 2 2 Apical membrane antigen 1 PNP_UDP_1 PF01048.20 CDJ58577.1 - 5e-11 42.3 0.0 5.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2111 PF09884.9 CDJ58577.1 - 0.065 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Dehydrin PF00257.19 CDJ58578.1 - 0.0013 19.3 6.2 0.0013 19.3 6.2 13.9 6 2 3 9 9 9 2 Dehydrin SPX PF03105.19 CDJ58578.1 - 7.4 6.4 118.9 0.33 10.8 14.1 6.1 6 0 0 6 6 6 0 SPX domain cNMP_binding PF00027.29 CDJ58579.1 - 2.1e-25 88.6 0.4 2.6e-18 65.9 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Mlh1_C PF16413.5 CDJ58580.1 - 0.019 14.3 26.0 0.41 10.0 5.0 4.5 4 0 0 4 4 4 0 DNA mismatch repair protein Mlh1 C-terminus DUF4834 PF16118.5 CDJ58580.1 - 0.61 11.1 49.1 0.83 10.7 10.1 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) DUF719 PF05334.13 CDJ58580.1 - 0.65 10.2 29.4 1.5 9.0 2.4 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF719) DUF4770 PF15994.5 CDJ58580.1 - 1.7 8.9 41.4 0.34 11.1 5.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4770) RPA43_OB PF17875.1 CDJ58580.1 - 2 9.1 20.8 5.8 7.5 3.0 4.4 4 0 0 4 4 4 0 RPA43 OB domain in RNA Pol I MecA PF05389.12 CDJ58580.1 - 2.2 7.9 29.7 0.3 10.7 2.8 4.2 3 1 0 4 4 4 0 Negative regulator of genetic competence (MecA) SAPS PF04499.15 CDJ58580.1 - 2.6 6.7 22.7 0.28 9.9 4.9 2.6 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein PRC2_HTH_1 PF18118.1 CDJ58580.1 - 7.6 7.4 27.5 36 5.2 5.9 4.8 4 0 0 4 4 4 0 Polycomb repressive complex 2 tri-helical domain Rer1 PF03248.13 CDJ58581.1 - 1.1e-61 207.5 1.7 1.3e-61 207.2 1.7 1.1 1 0 0 1 1 1 1 Rer1 family DAGAT PF03982.13 CDJ58582.1 - 1.9e-40 138.6 0.0 5.1e-38 130.7 0.0 2.2 1 1 1 2 2 2 2 Diacylglycerol acyltransferase Apt1 PF10351.9 CDJ58582.1 - 0.037 12.9 1.2 0.045 12.6 1.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PNISR PF15996.5 CDJ58582.1 - 0.051 13.9 7.1 0.077 13.3 7.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR AF-4 PF05110.13 CDJ58582.1 - 0.078 11.1 13.5 0.11 10.6 13.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 CDJ58582.1 - 0.094 11.5 5.4 0.13 11.0 5.4 1.2 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 CDJ58582.1 - 0.25 9.6 8.3 0.33 9.2 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPX PF03105.19 CDJ58582.1 - 0.92 9.4 12.3 1.3 8.8 12.3 1.1 1 0 0 1 1 1 0 SPX domain BNIP3 PF06553.12 CDJ58582.1 - 1.6 8.4 8.6 2.5 7.8 8.6 1.3 1 0 0 1 1 1 0 BNIP3 DUF4484 PF14831.6 CDJ58582.1 - 4.2 7.4 8.0 6.2 6.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF5427 PF10310.9 CDJ58582.1 - 7.1 5.5 12.1 9.2 5.1 12.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Spt20 PF12090.8 CDJ58583.1 - 0.66 9.5 6.6 1.4 8.5 6.6 1.5 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 CDJ58585.1 - 0.0013 18.7 5.4 0.018 15.1 0.1 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CDJ58585.1 - 2.3 9.1 21.8 0.42 11.5 1.7 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Pex14_N PF04695.13 CDJ58585.1 - 3.7 8.2 14.5 5.1 7.7 1.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ58585.1 - 4.9 6.7 8.9 2.3 7.8 2.2 2.2 2 0 0 2 2 2 0 Spt20 family LMF1 PF06762.14 CDJ58586.1 - 8.5e-39 133.9 0.1 3.5e-38 131.9 0.1 1.8 1 1 0 1 1 1 1 Lipase maturation factor XPG_I PF00867.18 CDJ58588.1 - 9.3e-20 70.8 0.6 2.2e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CDJ58588.1 - 0.00014 21.4 0.1 0.00021 20.9 0.1 1.4 1 1 0 1 1 1 1 XPG domain containing Rh5 PF18515.1 CDJ58588.1 - 0.058 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain TFIIE_beta PF02186.15 CDJ58588.1 - 0.12 12.7 0.5 4.8 7.6 0.0 2.3 2 0 0 2 2 2 0 TFIIE beta subunit core domain TSP_1 PF00090.19 CDJ58589.1 - 1.1e-101 332.9 232.8 1.5e-12 47.5 5.4 20.1 19 1 0 19 19 19 16 Thrombospondin type 1 domain Notch PF00066.17 CDJ58589.1 - 1.3e-26 92.7 84.9 2.1e-07 31.3 14.0 8.7 5 0 0 5 5 5 4 LNR domain Cwf_Cwc_15 PF04889.12 CDJ58591.1 - 0.0097 15.7 6.4 0.015 15.1 6.4 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Ric8 PF10165.9 CDJ58591.1 - 0.021 13.9 0.8 0.027 13.5 0.8 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Mcm10 PF09332.11 CDJ58591.1 - 0.021 14.3 15.7 0.034 13.6 15.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Lin-8 PF03353.15 CDJ58591.1 - 0.027 14.1 10.8 0.035 13.7 10.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 CDJ58591.1 - 0.032 14.6 4.3 0.056 13.8 4.3 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like TetR_C_20 PF17925.1 CDJ58591.1 - 0.057 13.7 0.7 0.057 13.7 0.7 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Band_3_cyto PF07565.13 CDJ58591.1 - 0.082 12.7 4.2 0.11 12.3 4.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BAF1_ABF1 PF04684.13 CDJ58591.1 - 0.11 11.5 8.6 0.21 10.6 8.6 1.4 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MMR1 PF08505.10 CDJ58591.1 - 0.17 12.2 13.1 0.25 11.6 13.1 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF775 PF05603.12 CDJ58591.1 - 0.19 11.2 12.3 0.36 10.4 12.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) ALMT PF11744.8 CDJ58591.1 - 0.22 10.3 5.0 0.26 10.1 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 CDJ58591.1 - 0.33 10.3 21.8 0.072 12.5 18.3 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 CDJ58591.1 - 0.37 10.7 45.8 0.49 10.3 45.4 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ58591.1 - 0.42 8.8 21.5 0.5 8.6 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ58591.1 - 0.81 8.3 9.5 1 8.0 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.13 CDJ58591.1 - 0.89 9.1 10.9 1.4 8.5 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 CDJ58591.1 - 1.2 9.2 8.0 1.9 8.5 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CDJ58591.1 - 1.9 7.2 9.3 2.9 6.6 9.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RCR PF12273.8 CDJ58591.1 - 2.1 9.0 15.4 4.2 8.0 15.4 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red GREB1 PF15782.5 CDJ58591.1 - 2.2 5.3 12.9 2.6 5.0 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CDJ58591.1 - 2.2 6.3 9.6 2.7 6.0 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAE2 PF08573.10 CDJ58591.1 - 2.9 9.0 12.2 8.2 7.6 12.2 1.7 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Presenilin PF01080.17 CDJ58591.1 - 3.8 6.2 14.1 5.6 5.6 14.1 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CDJ58591.1 - 5.5 6.7 8.0 7.9 6.2 8.0 1.2 1 0 0 1 1 1 0 Connexin GRP PF07172.11 CDJ58591.1 - 5.8 7.7 16.7 0.65 10.7 6.7 2.5 2 0 0 2 2 2 0 Glycine rich protein family Het-C PF07217.11 CDJ58591.1 - 8.8 4.7 10.0 12 4.2 10.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Exonuc_VII_L PF02601.15 CDJ58592.1 - 0.00068 19.3 11.8 0.00068 19.3 11.8 8.6 7 2 0 8 8 8 1 Exonuclease VII, large subunit DUF4207 PF13904.6 CDJ58592.1 - 0.004 16.9 2.7 0.004 16.9 2.7 13.0 12 2 2 14 14 14 2 Domain of unknown function (DUF4207) DUF2722 PF10846.8 CDJ58592.1 - 0.0089 15.0 0.1 0.0089 15.0 0.1 12.8 10 3 2 12 12 12 5 Protein of unknown function (DUF2722) Ribosomal_L6e PF01159.19 CDJ58593.1 - 0.00042 20.8 9.9 0.0008 19.9 9.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L6e FmiP_Thoc5 PF09766.9 CDJ58593.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.9 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 DUF4179 PF13786.6 CDJ58593.1 - 0.14 12.7 0.3 0.39 11.2 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Dynamin_N PF00350.23 CDJ58593.1 - 0.21 11.6 2.1 0.32 11.0 2.1 1.4 1 0 0 1 1 1 0 Dynamin family Late_protein_L2 PF00513.18 CDJ58593.1 - 0.3 10.1 4.1 0.35 9.8 4.1 1.1 1 0 0 1 1 1 0 Late Protein L2 FancD2 PF14631.6 CDJ58593.1 - 0.31 8.4 9.2 0.42 8.0 9.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CBP_BcsG PF11658.8 CDJ58593.1 - 0.46 8.8 2.0 0.55 8.6 2.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pox_Ag35 PF03286.14 CDJ58593.1 - 1.8 8.3 30.3 0.026 14.3 16.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3987 PF13148.6 CDJ58593.1 - 3.5 6.6 10.9 5.4 5.9 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Prothymosin PF03247.14 CDJ58593.1 - 4.2 7.9 48.5 2.4 8.7 24.7 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-N PF05238.13 CDJ58593.1 - 5.4 6.2 12.1 8.8 5.5 12.1 1.3 1 1 0 1 1 1 0 Kinetochore protein CHL4 like PA26 PF04636.13 CDJ58593.1 - 6.6 5.5 8.0 8.7 5.1 8.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) O-antigen_lig PF13425.6 CDJ58593.1 - 8.3 5.1 4.6 9.3 4.9 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RskA PF10099.9 CDJ58594.1 - 1.5e-06 28.7 10.5 0.0011 19.3 3.1 4.2 1 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF4887 PF16228.5 CDJ58594.1 - 0.0044 17.2 11.8 0.0044 17.2 11.8 7.3 6 2 1 7 7 7 3 Domain of unknown function (DUF4887) ADP_ribosyl_GH PF03747.14 CDJ58594.1 - 2.3 7.8 6.6 0.18 11.5 1.2 1.8 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase DUF4616 PF15394.6 CDJ58595.1 - 0.1 11.5 2.3 0.14 11.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Tyr_Deacylase PF02580.16 CDJ58596.1 - 2.1e-38 132.1 0.0 2.4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase OB_NTP_bind PF07717.16 CDJ58597.1 - 4e-17 62.4 0.1 1.2e-16 60.8 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ58597.1 - 1.1e-12 48.2 2.3 1.3e-12 48.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 CDJ58597.1 - 6.5e-11 42.5 0.1 6.5e-11 42.5 0.1 4.4 4 1 0 4 4 4 1 Helicase associated domain (HA2) DEAD PF00270.29 CDJ58597.1 - 8.9e-07 28.8 0.2 2.3e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ58597.1 - 4.3e-06 27.0 1.2 3.8e-05 24.0 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 CDJ58597.1 - 0.0039 17.7 2.2 4.8 7.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CDJ58597.1 - 0.015 15.2 0.1 0.081 12.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CDJ58597.1 - 0.081 13.3 0.2 0.081 13.3 0.2 4.2 2 1 0 2 2 2 0 AAA ATPase domain U1snRNP70_N PF12220.8 CDJ58597.1 - 5.4 7.7 10.9 2.1 9.0 2.6 3.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal WD40 PF00400.32 CDJ58598.1 - 1.1e-15 57.7 7.0 0.00027 21.7 0.8 5.4 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ58598.1 - 1.3e-08 35.0 0.0 0.37 11.1 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CDJ58598.1 - 0.0027 17.2 0.0 0.0065 15.9 0.0 1.7 1 0 0 1 1 1 1 EF hand PQQ PF01011.21 CDJ58598.1 - 0.0083 16.0 0.3 7.8 6.6 0.0 4.0 3 1 1 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 CDJ58598.1 - 0.0096 15.3 0.0 0.86 8.9 0.0 2.0 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 CDJ58598.1 - 0.86 10.2 3.4 19 5.9 0.0 4.2 6 0 0 6 6 6 0 PQQ-like domain RCC1_2 PF13540.6 CDJ58599.1 - 6.9e-05 22.5 1.9 0.011 15.5 0.4 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ58599.1 - 0.00072 20.1 0.7 2.5 8.8 0.0 3.6 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat PDEase_I PF00233.19 CDJ58600.1 - 1.7e-60 204.7 6.1 6e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase CBM_48 PF02922.18 CDJ58601.1 - 1.3e-21 76.7 0.0 7.7e-21 74.3 0.0 2.4 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 CDJ58601.1 - 1.8e-19 70.0 0.0 9.9e-19 67.6 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CDJ58601.1 - 1.5e-14 54.3 0.3 5.1e-06 26.3 0.0 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CDJ58601.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Peptidase_S49_N PF08496.10 CDJ58602.1 - 0.62 10.1 14.4 0.37 10.8 3.8 2.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Connexin PF00029.19 CDJ58602.1 - 3.8 7.2 7.1 4 7.1 2.2 2.4 2 0 0 2 2 2 0 Connexin MecA PF05389.12 CDJ58602.1 - 4.3 6.9 10.3 0.92 9.1 1.8 2.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) SDH_alpha PF03313.15 CDJ58603.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Serine dehydratase alpha chain DUF572 PF04502.13 CDJ58603.1 - 0.48 10.0 23.6 0.65 9.6 23.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 CDJ58603.1 - 4.3 5.1 20.3 5.8 4.7 20.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.9 CDJ58604.1 - 0.14 11.0 1.1 0.13 11.1 1.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_lid_5 PF17865.1 CDJ58604.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Midasin AAA lid domain SPX PF03105.19 CDJ58604.1 - 3.2 7.6 7.2 3.7 7.4 7.2 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CDJ58604.1 - 9.4 5.3 11.0 11 5.1 11.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein K_channel_TID PF07941.11 CDJ58605.1 - 0.0046 17.4 8.6 0.0046 17.4 8.6 10.5 10 1 1 11 11 11 3 Potassium channel Kv1.4 tandem inactivation domain Band_3_cyto PF07565.13 CDJ58605.1 - 2 8.2 12.6 1.1 8.9 1.8 3.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MecA PF05389.12 CDJ58605.1 - 2.5 7.7 9.0 0.45 10.1 0.4 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) RCC1_2 PF13540.6 CDJ58607.1 - 3e-13 49.2 15.4 2e-09 37.0 0.1 4.4 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CDJ58607.1 - 2.1e-05 25.0 11.9 0.032 14.9 0.1 5.5 4 3 1 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat TauE PF01925.19 CDJ58609.1 - 1.7e-21 77.0 25.6 7.7e-12 45.3 0.6 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF4328 PF14219.6 CDJ58609.1 - 0.00011 21.9 0.1 0.00033 20.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) FAM104 PF15434.6 CDJ58611.1 - 0.15 12.6 1.5 0.89 10.1 0.2 2.4 2 0 0 2 2 2 0 Family 104 Myb_DNA-bind_7 PF15963.5 CDJ58614.1 - 1.6e-22 79.2 0.3 8.8e-22 76.8 0.3 2.4 1 0 0 1 1 1 1 Myb DNA-binding like HMG_box_2 PF09011.10 CDJ58614.1 - 2.1e-05 25.0 7.0 0.11 13.2 0.8 4.2 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 CDJ58614.1 - 0.00064 20.1 4.3 1.7 9.1 2.3 3.8 3 0 0 3 3 3 2 HMG (high mobility group) box Myb_DNA-binding PF00249.31 CDJ58614.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain FrhB_FdhB_N PF04422.13 CDJ58615.1 - 0.4 10.9 4.5 10 6.4 0.2 3.7 3 1 1 4 4 4 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PA PF02225.22 CDJ58616.1 - 2.8e-06 27.2 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF1422 PF07226.11 CDJ58616.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) PspB PF06667.12 CDJ58616.1 - 0.14 12.2 0.5 0.24 11.5 0.5 1.4 1 0 0 1 1 1 0 Phage shock protein B Vma12 PF11712.8 CDJ58617.1 - 0.72 9.9 6.8 0.15 12.1 0.5 2.6 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Citrate_synt PF00285.21 CDJ58618.1 - 9.1e-86 288.2 0.0 1.1e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain RT_RNaseH_2 PF17919.1 CDJ58619.1 - 8e-30 102.8 0.2 1.7e-29 101.7 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ58619.1 - 3.6e-29 101.1 0.1 1e-28 99.7 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ58619.1 - 2.2e-22 79.7 0.0 4.2e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDJ58619.1 - 5.1e-15 55.3 0.5 3.2e-14 52.7 0.3 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RVP_2 PF08284.11 CDJ58619.1 - 5.5e-09 35.9 0.0 9.4e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDJ58619.1 - 1e-06 29.2 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.26 CDJ58619.1 - 1.8e-06 28.1 0.2 2.3e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 CDJ58619.1 - 2.8e-06 27.9 0.0 6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDJ58619.1 - 0.0095 16.2 0.0 0.053 13.8 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_3 PF13456.6 CDJ58619.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Asp_protease PF09668.10 CDJ58619.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-DNL PF05180.12 CDJ58620.1 - 0.00016 21.5 0.1 0.00027 20.8 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger FSA_C PF10479.9 CDJ58620.1 - 0.71 7.9 2.5 0.88 7.6 2.5 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Methyltransf_11 PF08241.12 CDJ58621.1 - 3.7e-13 49.9 0.2 7.6e-12 45.7 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ58621.1 - 2.8e-10 40.8 0.6 6.5e-09 36.4 0.4 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ58621.1 - 1.6e-06 28.0 0.0 3.9e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ58621.1 - 8.5e-06 26.4 0.1 0.00012 22.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ58621.1 - 0.00023 21.0 0.6 0.00066 19.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain FmiP_Thoc5 PF09766.9 CDJ58621.1 - 0.006 15.9 3.5 0.0088 15.4 3.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Methyltransf_9 PF08003.11 CDJ58621.1 - 0.093 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NNMT_PNMT_TEMT PF01234.17 CDJ58621.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TMEM208_SND2 PF05620.11 CDJ58621.1 - 4.9 6.9 6.8 7.8 6.2 6.8 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CDC45 PF02724.14 CDJ58621.1 - 8.7 4.5 6.3 12 4.1 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 CDJ58621.1 - 8.8 4.7 8.6 12 4.2 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Filamin PF00630.19 CDJ58623.1 - 1.5e-06 28.9 0.0 0.026 15.3 0.0 3.4 2 1 1 3 3 3 2 Filamin/ABP280 repeat FapA PF03961.13 CDJ58623.1 - 0.9 8.1 15.8 1.6 7.2 15.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CDJ58623.1 - 3.2 6.5 9.9 5.2 5.9 9.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_REV PF03978.13 CDJ58623.1 - 4.1 7.3 10.6 0.55 10.2 5.3 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Dpy-30 PF05186.13 CDJ58626.1 - 3e-06 26.8 0.0 6.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif BT1 PF03092.16 CDJ58626.1 - 0.033 12.4 3.0 0.76 7.9 0.1 2.5 2 1 0 2 2 2 0 BT1 family TFIIA PF03153.13 CDJ58626.1 - 1.2 9.1 27.2 1.3 8.9 13.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Trypsin_2 PF13365.6 CDJ58627.1 - 3.7e-11 44.1 3.3 1.5e-07 32.4 0.5 2.9 1 1 1 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 CDJ58627.1 - 3.7e-08 33.1 0.5 1.1e-07 31.6 0.5 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDJ58627.1 - 3.4e-06 27.3 0.0 1e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDJ58627.1 - 0.00012 22.4 0.1 0.00023 21.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 CDJ58627.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.6 1 1 0 1 1 1 0 Trypsin Peptidase_S29 PF02907.15 CDJ58627.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease TraL PF07178.11 CDJ58630.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 TraL protein SelP_C PF04593.14 CDJ58631.1 - 0.023 14.7 0.5 0.05 13.6 0.2 1.7 2 0 0 2 2 2 0 Selenoprotein P, C terminal region MobL PF18555.1 CDJ58631.1 - 5.4 6.2 10.4 1.3 8.2 1.9 2.0 1 1 1 2 2 2 0 MobL relaxases AIP3 PF03915.13 CDJ58632.1 - 0.00024 20.3 2.9 0.00033 19.9 2.9 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF745 PF05335.13 CDJ58632.1 - 0.026 14.3 1.2 0.04 13.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 CDJ58632.1 - 3.2 7.9 9.0 0.14 12.3 3.5 1.5 2 0 0 2 2 2 0 Tropomyosin like Phage_AlpA PF05930.12 CDJ58633.1 - 0.028 14.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Asp-B-Hydro_N PF05279.11 CDJ58633.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Calreticulin PF00262.18 CDJ58634.1 - 5.1e-13 48.6 0.0 6.1e-09 35.2 0.0 3.2 1 1 2 3 3 3 3 Calreticulin family Methyltransf_32 PF13679.6 CDJ58634.1 - 0.2 11.7 0.0 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cullin PF00888.22 CDJ58635.1 - 3.9e-11 42.3 0.0 5.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ58635.1 - 4.6e-11 42.6 0.1 8.5e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_Crp_2 PF13545.6 CDJ58635.1 - 0.027 14.4 0.1 3.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ComX PF05952.12 CDJ58635.1 - 0.072 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX AAA_6 PF12774.7 CDJ58637.1 - 3.2e-148 493.0 0.6 6.6e-147 488.7 0.1 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ58637.1 - 5.2e-120 401.2 3.8 5.2e-120 401.2 3.8 5.1 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CDJ58637.1 - 1.5e-81 272.8 0.7 1.5e-81 272.8 0.7 3.6 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ58637.1 - 2e-77 258.8 0.0 2e-71 239.3 0.0 3.5 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 CDJ58637.1 - 8.4e-50 167.8 0.4 3.7e-43 146.4 0.0 4.5 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CDJ58637.1 - 6.2e-48 163.6 6.1 7.3e-47 160.1 0.0 4.6 3 1 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDJ58637.1 - 8.2e-43 146.6 0.8 5.3e-42 143.9 0.1 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 MT PF12777.7 CDJ58637.1 - 1e-35 123.4 18.0 1.7e-30 106.2 11.9 3.2 2 1 0 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ58637.1 - 2.7e-27 95.6 0.4 1.5e-19 70.4 0.0 2.9 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ58637.1 - 6.8e-23 81.2 0.0 5.4e-07 29.7 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ58637.1 - 1.1e-22 80.5 0.0 4.3e-22 78.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ58637.1 - 3.2e-21 75.4 0.1 1e-20 73.8 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ58637.1 - 3e-08 34.1 0.8 0.024 15.0 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ58637.1 - 3.6e-07 30.5 0.1 3 8.1 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 CDJ58637.1 - 4.6e-05 23.9 2.2 1.6 9.1 0.0 5.2 4 0 0 4 4 3 1 AAA ATPase domain Phage_GP20 PF06810.11 CDJ58637.1 - 5.9e-05 22.9 11.0 5.9e-05 22.9 11.0 3.5 4 1 1 5 5 3 1 Phage minor structural protein GP20 T2SSE PF00437.20 CDJ58637.1 - 0.00023 20.3 1.0 0.088 11.9 0.1 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 CDJ58637.1 - 0.00095 18.6 0.5 2.4 7.5 0.0 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ58637.1 - 0.0021 18.6 0.0 0.19 12.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDJ58637.1 - 0.0021 18.4 0.0 0.54 10.7 0.0 3.5 3 0 0 3 3 3 1 RNA helicase DEAD PF00270.29 CDJ58637.1 - 0.0076 16.0 0.0 1.6 8.5 0.0 3.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TsaE PF02367.17 CDJ58637.1 - 0.045 13.8 0.6 14 5.7 0.1 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EzrA PF06160.12 CDJ58637.1 - 0.054 11.7 16.4 1.3 7.1 0.0 3.8 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA AbiJ_NTD4 PF18863.1 CDJ58637.1 - 0.059 13.8 0.1 0.48 10.9 0.0 2.6 3 0 0 3 3 1 0 AbiJ N-terminal domain 4 DUF853 PF05872.12 CDJ58637.1 - 0.063 11.9 11.9 0.39 9.3 0.1 3.7 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 CDJ58637.1 - 0.14 12.3 0.6 40 4.3 0.0 4.7 5 0 0 5 5 5 0 AAA domain AAA_30 PF13604.6 CDJ58637.1 - 0.23 11.2 8.4 1.9 8.2 0.0 4.0 4 0 0 4 4 3 0 AAA domain rve_2 PF13333.6 CDJ58637.1 - 0.25 11.6 0.9 0.99 9.6 0.9 2.0 1 0 0 1 1 1 0 Integrase core domain AAA_28 PF13521.6 CDJ58637.1 - 0.25 11.6 4.1 6.7 6.9 0.0 4.3 5 0 0 5 5 3 0 AAA domain LMBR1 PF04791.16 CDJ58637.1 - 1.6 7.6 9.7 0.12 11.3 2.8 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein DASH_Hsk3 PF08227.11 CDJ58637.1 - 1.7 9.0 5.2 15 6.0 5.2 2.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like AAA_25 PF13481.6 CDJ58637.1 - 2 7.9 6.6 18 4.8 0.1 3.8 4 0 0 4 4 3 0 AAA domain DUF3138 PF11336.8 CDJ58637.1 - 2.1 6.9 5.6 3.4 6.2 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_1 PF00170.21 CDJ58637.1 - 9.8 6.4 7.9 0.58 10.3 1.0 2.7 2 0 0 2 2 1 0 bZIP transcription factor SNAPc_SNAP43 PF09808.9 CDJ58638.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 tRNA-synt_His PF13393.6 CDJ58640.1 - 9.1e-12 44.9 0.8 1.2e-06 28.0 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase Cyclin PF08613.11 CDJ58641.1 - 1.6e-06 28.6 0.1 2.4e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CDJ58641.1 - 0.048 13.4 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain SMP_2 PF10144.9 CDJ58641.1 - 0.81 9.3 3.3 3.7 7.2 0.4 2.4 2 1 0 2 2 2 0 Bacterial virulence factor haemolysin Hydrolase_4 PF12146.8 CDJ58642.1 - 7e-20 71.3 0.3 1.6e-08 34.1 0.0 3.1 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ58642.1 - 7.2e-05 23.5 4.4 0.00063 20.4 4.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family COPI_assoc PF08507.10 CDJ58643.1 - 1.4e-05 25.1 0.4 1.6e-05 25.0 0.4 1.1 1 0 0 1 1 1 1 COPI associated protein LRR_8 PF13855.6 CDJ58646.1 - 2.2e-06 27.3 6.3 8e-05 22.3 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CDJ58646.1 - 0.015 15.7 7.5 0.039 14.4 0.3 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDJ58646.1 - 0.029 13.9 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Flg_bb_rod PF00460.20 CDJ58647.1 - 0.0029 17.5 5.5 0.6 10.1 0.3 2.4 2 0 0 2 2 2 2 Flagella basal body rod protein Myosin_head PF00063.21 CDJ58648.1 - 5.2e-174 580.2 0.0 6.8e-174 579.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.18 CDJ58648.1 - 1.1e-05 25.6 0.1 0.0031 17.8 0.0 3.0 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_16 PF13191.6 CDJ58648.1 - 0.015 15.7 0.0 0.075 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ58648.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ58648.1 - 0.14 12.4 0.0 0.78 10.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain RskA PF10099.9 CDJ58649.1 - 0.01 16.1 7.6 0.01 16.1 7.6 5.1 4 1 1 5 5 5 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ58649.1 - 0.34 10.5 42.3 0.2 11.2 16.3 2.9 3 0 0 3 3 3 0 Spt20 family Neur_chan_memb PF02932.16 CDJ58649.1 - 3.6 7.6 5.7 19 5.2 0.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1645 PF07816.11 CDJ58649.1 - 8.6 6.9 31.2 0.48 11.0 3.5 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1645) UPF0561 PF10573.9 CDJ58651.1 - 0.5 10.5 3.3 0.81 9.8 3.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 Phage_rep_org_N PF09681.10 CDJ58652.1 - 1.5 8.8 5.0 4.8 7.1 5.0 1.8 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Alpha_GJ PF03229.13 CDJ58653.1 - 7.7 7.1 22.3 0.1 13.1 7.4 3.3 3 0 0 3 3 3 0 Alphavirus glycoprotein J Kelch_3 PF13415.6 CDJ58655.1 - 1.2e-18 66.9 10.4 6.4e-05 23.1 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ58655.1 - 1.8e-13 50.3 1.6 0.0044 17.0 0.0 6.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Spt20 PF12090.8 CDJ58655.1 - 2.9e-09 36.9 29.7 2.1e-06 27.5 8.9 3.4 3 0 0 3 3 3 3 Spt20 family Kelch_5 PF13854.6 CDJ58655.1 - 8.7e-08 32.0 9.6 0.00026 20.9 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CDJ58655.1 - 9.4e-08 31.5 2.6 0.0019 17.7 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDJ58655.1 - 1.9e-07 31.1 7.8 0.0012 19.1 0.1 4.6 4 1 0 4 4 3 2 Kelch motif DUF2722 PF10846.8 CDJ58655.1 - 3.2e-06 26.4 5.0 3.2e-06 26.4 5.0 3.8 3 1 1 4 4 3 1 Protein of unknown function (DUF2722) Kelch_2 PF07646.15 CDJ58655.1 - 4e-05 23.4 12.0 0.00016 21.5 0.2 4.5 4 1 0 4 4 4 1 Kelch motif CCDC53 PF10152.9 CDJ58655.1 - 0.0023 18.4 2.0 0.0023 18.4 2.0 3.5 3 1 0 3 3 2 1 Subunit CCDC53 of WASH complex Suf PF05843.14 CDJ58655.1 - 0.0036 17.3 6.6 0.0036 17.3 6.6 3.0 2 1 1 3 3 2 1 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 CDJ58655.1 - 0.0069 16.4 2.6 0.0069 16.4 2.6 5.2 5 1 0 5 5 2 2 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ58655.1 - 0.018 15.7 11.0 0.018 15.7 11.0 3.4 3 1 0 3 3 2 0 Protein of unknown function (DUF1645) THOC2_N PF16134.5 CDJ58655.1 - 0.12 11.0 4.7 0.18 10.4 0.2 2.3 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus eIF-3_zeta PF05091.12 CDJ58655.1 - 0.52 9.2 13.7 1.3 7.9 6.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 CDJ58655.1 - 0.99 9.6 12.7 0.34 11.1 4.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF4366 PF14283.6 CDJ58655.1 - 1.6 8.8 10.5 0.78 9.8 0.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4366) BUD22 PF09073.10 CDJ58656.1 - 0.77 9.0 49.6 0.0044 16.4 2.2 6.4 5 1 0 6 6 6 0 BUD22 TRAP_alpha PF03896.16 CDJ58656.1 - 8.6 5.5 7.4 1.9 7.6 1.1 2.9 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit MRI PF15325.6 CDJ58658.1 - 0.09 13.9 4.0 0.11 13.6 4.0 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection CbtA PF09490.10 CDJ58658.1 - 0.24 11.1 6.0 0.27 10.9 6.0 1.0 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) RskA PF10099.9 CDJ58659.1 - 4.8e-05 23.7 45.5 0.0084 16.4 0.0 4.4 2 2 2 4 4 4 3 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ58659.1 - 0.022 15.3 3.9 0.022 15.3 3.9 4.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein Macoilin PF09726.9 CDJ58660.1 - 0.0019 16.9 25.7 0.0019 16.9 25.7 6.9 7 2 0 7 7 7 2 Macoilin family IMUP PF15761.5 CDJ58660.1 - 0.0046 17.6 7.2 0.0046 17.6 7.2 11.2 9 2 3 12 12 12 1 Immortalisation up-regulated protein NAM-associated PF14303.6 CDJ58660.1 - 4.6 7.9 0.0 4.6 7.9 0.0 9.4 7 2 1 8 8 8 0 No apical meristem-associated C-terminal domain RAP1 PF07218.11 CDJ58661.1 - 0.1 10.9 1.2 0.15 10.3 1.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1645 PF07816.11 CDJ58661.1 - 0.44 11.1 12.5 0.14 12.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) EIF4E-T PF10477.9 CDJ58661.1 - 1 8.1 26.0 0.11 11.2 21.8 1.5 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PRP1_N PF06424.12 CDJ58661.1 - 1.1 9.6 22.9 0.19 12.1 19.0 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Sas10_Utp3 PF04000.15 CDJ58661.1 - 5 7.8 11.3 50 4.6 7.2 2.6 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Exo_endo_phos PF03372.23 CDJ58662.1 - 0.00057 19.5 2.3 0.0011 18.6 0.0 2.5 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family GpcrRhopsn4 PF10192.9 CDJ58663.1 - 6.5e-09 35.6 1.9 8.2e-09 35.2 0.9 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain SUIM_assoc PF16619.5 CDJ58663.1 - 0.0069 16.4 0.0 1.6 8.9 4.1 2.2 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4719 PF15843.5 CDJ58663.1 - 0.0074 16.4 1.2 0.098 12.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4719) 7TMR-DISM_7TM PF07695.11 CDJ58663.1 - 0.026 14.4 5.3 0.042 13.7 5.3 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling TspO_MBR PF03073.15 CDJ58663.1 - 0.032 14.3 5.3 0.069 13.2 5.3 1.6 1 0 0 1 1 1 0 TspO/MBR family CS PF04969.16 CDJ58664.1 - 1.3e-15 58.1 0.4 2e-15 57.6 0.4 1.3 1 0 0 1 1 1 1 CS domain SGS PF05002.15 CDJ58664.1 - 9.9e-08 32.0 4.4 1.3e-07 31.6 2.8 2.2 2 1 0 2 2 2 1 SGS domain URO-D PF01208.17 CDJ58665.1 - 4.2e-67 226.7 0.0 3.9e-66 223.6 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Chorion_2 PF03964.15 CDJ58665.1 - 0.32 11.9 2.5 0.69 10.8 2.5 1.5 1 0 0 1 1 1 0 Chorion family 2 SpoIIP PF07454.11 CDJ58666.1 - 0.0045 16.5 8.5 0.01 15.3 8.5 1.6 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CDJ58666.1 - 0.027 15.1 25.2 0.027 15.1 25.2 3.6 4 1 0 4 4 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 CDJ58666.1 - 0.21 10.5 6.2 0.56 9.1 6.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ58666.1 - 0.45 9.7 1.8 0.67 9.1 1.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Rxt3 PF08642.10 CDJ58666.1 - 0.77 10.5 6.3 2.8 8.7 6.3 2.0 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 OATP PF03137.20 CDJ58666.1 - 0.9 7.7 4.6 1.3 7.2 4.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family F-protein PF00469.20 CDJ58666.1 - 0.99 9.0 9.8 0.088 12.4 4.3 2.0 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Tim54 PF11711.8 CDJ58666.1 - 1.1 8.0 15.9 3.5 6.3 15.9 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 CDJ58666.1 - 1.4 7.0 10.9 2.2 6.3 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ureide_permease PF07168.11 CDJ58666.1 - 1.4 7.6 2.1 2.2 6.9 2.1 1.3 1 0 0 1 1 1 0 Ureide permease PRIMA1 PF16101.5 CDJ58666.1 - 1.4 8.9 5.5 3.4 7.7 5.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Borrelia_P83 PF05262.11 CDJ58666.1 - 1.7 7.0 13.7 2.4 6.6 13.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 CDJ58666.1 - 2.1 8.2 64.7 0.3 11.0 47.9 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Membralin PF09746.9 CDJ58666.1 - 2.3 7.2 4.3 3.7 6.5 4.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Lin-8 PF03353.15 CDJ58666.1 - 2.9 7.4 25.2 0.051 13.1 13.1 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist NARP1 PF12569.8 CDJ58666.1 - 3.2 6.6 13.1 5.4 5.8 13.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.14 CDJ58666.1 - 3.6 7.5 27.8 0.038 14.0 17.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Eapp_C PF10238.9 CDJ58666.1 - 4.2 7.4 15.7 0.3 11.2 9.8 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Asparaginase_2 PF01112.18 CDJ58666.1 - 4.6 6.2 5.4 7.5 5.5 5.4 1.3 1 0 0 1 1 1 0 Asparaginase FHIPEP PF00771.20 CDJ58666.1 - 6.5 5.1 6.3 12 4.3 6.3 1.4 1 0 0 1 1 1 0 FHIPEP family CLN3 PF02487.17 CDJ58666.1 - 6.7 5.6 10.3 13 4.7 10.3 1.4 1 0 0 1 1 1 0 CLN3 protein MDM10 PF12519.8 CDJ58666.1 - 7.2 5.4 13.0 0.17 10.7 6.6 1.6 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Glyco_transf_15 PF01793.16 CDJ58666.1 - 7.6 5.7 8.3 13 4.9 8.3 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Connexin PF00029.19 CDJ58666.1 - 7.7 6.2 11.3 17 5.1 11.3 1.5 1 0 0 1 1 1 0 Connexin Pannexin_like PF12534.8 CDJ58666.1 - 9.2 5.2 18.8 0.15 11.2 11.7 1.6 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Surface_antigen PF11054.8 CDJ58667.1 - 2.7e-16 60.0 2.9 5e-09 36.2 3.5 3.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Histone_HNS PF00816.21 CDJ58667.1 - 0.63 10.9 2.0 1.9 9.4 0.1 2.4 3 0 0 3 3 3 0 H-NS histone family Surface_antigen PF11054.8 CDJ58668.1 - 1e-09 38.5 6.8 1.1e-08 35.1 3.5 2.9 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen SR-25 PF10500.9 CDJ58669.1 - 4.6e-07 29.7 5.0 4.6e-07 29.7 5.0 5.7 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ58669.1 - 0.0029 17.9 4.5 0.0029 17.9 4.5 4.9 4 1 0 4 4 4 3 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ58669.1 - 0.0039 16.2 7.5 0.0039 16.2 7.5 5.2 5 0 0 5 5 5 2 Protein of unknown function (DUF2722) Mak16 PF04874.14 CDJ58669.1 - 0.015 15.9 5.4 0.015 15.9 5.4 5.0 6 0 0 6 6 6 0 Mak16 protein C-terminal region DUF3446 PF11928.8 CDJ58669.1 - 1.2 9.5 19.6 1.5 9.2 3.8 3.5 4 0 0 4 4 4 0 Early growth response N-terminal domain PP2C PF00481.21 CDJ58672.1 - 6.2e-39 134.2 0.0 8.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CDJ58672.1 - 3.4e-06 27.1 0.0 2.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDJ58672.1 - 6.8e-06 25.9 0.0 7.8e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Mac PF12464.8 CDJ58673.1 - 0.3 11.3 4.5 3.6 7.9 0.5 3.4 3 1 0 3 3 3 0 Maltose acetyltransferase CSD PF00313.22 CDJ58674.1 - 8.4e-23 80.0 0.2 1.3e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Prenyltrans PF00432.21 CDJ58675.1 - 1.2e-08 34.5 9.8 0.19 11.5 0.0 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pkinase PF00069.25 CDJ58676.1 - 4.7e-60 203.2 0.0 7.3e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58676.1 - 5.7e-36 124.1 0.0 1.5e-35 122.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ58676.1 - 0.0006 18.7 0.2 0.0026 16.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase UPF0113_N PF17833.1 CDJ58678.1 - 1.5e-26 92.8 0.1 2.2e-26 92.2 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDJ58678.1 - 1.8e-17 63.3 0.0 3.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain MMR_HSR1 PF01926.23 CDJ58679.1 - 4e-09 36.6 0.0 7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ58679.1 - 0.0036 16.8 0.0 0.028 13.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CDJ58679.1 - 0.017 14.5 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CDJ58679.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 CDJ58679.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DEAD PF00270.29 CDJ58680.1 - 1.7e-45 154.9 0.1 2.3e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58680.1 - 2.6e-28 98.6 1.0 1.2e-27 96.5 0.2 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CDJ58680.1 - 0.0094 16.3 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 CDJ58680.1 - 0.054 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_60s PF00428.19 CDJ58682.1 - 0.15 12.7 4.5 0.25 11.9 4.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M17 PF00883.21 CDJ58683.1 - 1.4e-76 257.7 13.7 6.8e-61 206.2 6.7 2.5 2 1 0 3 3 3 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CDJ58683.1 - 0.025 14.4 0.1 0.025 14.4 0.1 4.5 3 2 1 4 4 4 0 Cytosol aminopeptidase family, N-terminal domain Thioredoxin PF00085.20 CDJ58684.1 - 3.1e-09 36.7 0.0 0.0014 18.6 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Flavodoxin_5 PF12724.7 CDJ58684.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain EMP24_GP25L PF01105.24 CDJ58685.1 - 1.8e-21 76.9 0.0 2.4e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2183 PF09949.9 CDJ58686.1 - 0.0034 17.7 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pkinase PF00069.25 CDJ58688.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 CDJ58689.1 - 5.5e-40 137.4 0.2 1.4e-39 136.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58689.1 - 7.2e-18 64.8 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MITF_TFEB_C_3_N PF15951.5 CDJ58689.1 - 0.02 15.5 7.4 0.02 15.5 7.4 7.9 6 2 2 9 9 9 0 MITF/TFEB/TFEC/TFE3 N-terminus DUF2722 PF10846.8 CDJ58689.1 - 0.27 10.1 0.0 0.27 10.1 0.0 5.9 4 2 0 4 4 4 0 Protein of unknown function (DUF2722) RIFIN PF02009.16 CDJ58690.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.6 2 1 1 3 3 3 0 Rifin SR-25 PF10500.9 CDJ58690.1 - 0.34 10.5 48.6 0.12 12.0 18.9 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 CDJ58690.1 - 1.2 8.9 22.6 0.085 12.7 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) Mitofilin PF09731.9 CDJ58690.1 - 4.6 5.9 13.3 1.9 7.2 2.8 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Fumble PF03630.14 CDJ58691.1 - 1.5e-27 96.7 0.4 1.3e-23 83.7 0.1 5.4 4 2 2 6 6 6 2 Fumble DUF2722 PF10846.8 CDJ58691.1 - 0.00016 20.8 6.5 0.00016 20.8 6.5 7.5 6 2 0 6 6 6 2 Protein of unknown function (DUF2722) Presenilin PF01080.17 CDJ58692.1 - 0.019 13.8 3.4 0.023 13.5 3.4 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ58692.1 - 0.027 14.5 12.1 0.035 14.1 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.13 CDJ58692.1 - 0.12 10.4 21.2 0.16 10.1 21.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Totivirus_coat PF05518.11 CDJ58692.1 - 0.26 9.3 8.4 0.31 9.1 8.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein Plasmodium_Vir PF05795.11 CDJ58692.1 - 0.44 9.9 3.6 0.49 9.8 3.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ58692.1 - 0.66 9.5 8.5 0.9 9.0 8.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 CDJ58692.1 - 1.8 7.3 9.5 2.3 7.0 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GAS PF13851.6 CDJ58693.1 - 2.3 7.5 42.5 0.072 12.4 15.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Peptidase_M22 PF00814.25 CDJ58694.1 - 3.1e-72 243.5 0.2 1e-53 182.8 0.3 2.2 1 1 1 2 2 2 2 Glycoprotease family Kelch_2 PF07646.15 CDJ58695.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Kelch motif EGF_2 PF07974.13 CDJ58695.1 - 0.64 10.4 9.3 1.5 9.3 9.3 1.6 1 0 0 1 1 1 0 EGF-like domain IPK PF03770.16 CDJ58696.1 - 2.2e-09 37.5 1.8 2.2e-09 37.5 1.8 4.5 3 1 0 4 4 4 1 Inositol polyphosphate kinase DUF2722 PF10846.8 CDJ58696.1 - 0.0073 15.3 15.6 0.0073 15.3 15.6 6.0 2 1 2 5 5 5 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ58696.1 - 0.0084 14.9 36.9 0.13 11.0 9.9 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ58696.1 - 0.022 15.0 13.5 0.17 12.2 4.2 3.3 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Photo_RC PF00124.19 CDJ58696.1 - 0.33 10.1 0.1 0.79 8.9 0.1 1.6 1 0 0 1 1 1 0 Photosynthetic reaction centre protein TPK_catalytic PF04263.16 CDJ58697.1 - 9e-28 96.7 0.0 1.5e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDJ58697.1 - 1.7e-13 50.1 0.0 2.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Plasmodium_Vir PF05795.11 CDJ58698.1 - 0.0036 16.8 5.8 0.0036 16.8 5.8 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Lin-8 PF03353.15 CDJ58698.1 - 0.0042 16.7 17.8 0.0053 16.4 17.8 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 CDJ58698.1 - 0.0052 16.3 8.1 0.0071 15.8 8.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Ctr PF04145.15 CDJ58698.1 - 0.007 17.0 6.7 0.007 17.0 6.7 2.0 1 1 1 2 2 2 1 Ctr copper transporter family Apt1 PF10351.9 CDJ58698.1 - 0.0078 15.1 17.1 0.0094 14.9 17.1 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ58698.1 - 0.014 15.4 18.1 0.017 15.1 18.1 1.0 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CDJ58698.1 - 0.018 13.7 19.0 0.021 13.4 19.0 1.0 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 CDJ58698.1 - 0.023 14.5 19.9 0.027 14.2 19.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 FHIPEP PF00771.20 CDJ58698.1 - 0.04 12.4 2.7 0.048 12.1 2.7 1.1 1 0 0 1 1 1 0 FHIPEP family Presenilin PF01080.17 CDJ58698.1 - 0.043 12.6 17.6 0.06 12.1 17.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 CDJ58698.1 - 0.055 11.4 20.9 0.062 11.2 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.14 CDJ58698.1 - 0.11 10.8 12.5 0.15 10.4 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 CDJ58698.1 - 0.13 12.3 31.3 0.17 11.9 31.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 CDJ58698.1 - 0.15 12.6 19.2 0.061 13.9 4.3 2.1 2 0 0 2 2 2 0 TCP family transcription factor Peptidase_S64 PF08192.11 CDJ58698.1 - 0.26 9.7 20.5 0.31 9.5 20.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 CDJ58698.1 - 0.29 9.2 17.2 0.39 8.8 17.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.10 CDJ58698.1 - 0.39 9.4 29.1 0.48 9.1 29.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1645 PF07816.11 CDJ58698.1 - 0.43 11.1 23.2 1 9.9 23.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) GREB1 PF15782.5 CDJ58698.1 - 0.71 6.9 21.6 0.8 6.7 21.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPF0239 PF06783.11 CDJ58698.1 - 1.2 9.3 8.6 0.26 11.5 3.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) SLC12 PF03522.15 CDJ58698.1 - 1.6 7.7 16.5 2.1 7.3 16.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 AUX_IAA PF02309.16 CDJ58698.1 - 2.2 8.1 10.0 3.2 7.5 10.0 1.2 1 0 0 1 1 1 0 AUX/IAA family HSD3 PF15244.6 CDJ58698.1 - 2.3 7.6 26.0 2.9 7.3 26.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 DUF4598 PF15370.6 CDJ58698.1 - 2.5 8.6 17.1 1.5 9.4 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) DUF3408 PF11888.8 CDJ58698.1 - 2.7 8.2 14.3 0.28 11.3 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) YfhO PF09586.10 CDJ58698.1 - 2.7 6.1 9.9 0.39 8.9 5.8 1.4 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Eapp_C PF10238.9 CDJ58698.1 - 3 7.9 23.8 0.098 12.7 11.9 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein RAP1 PF07218.11 CDJ58698.1 - 4.3 5.5 13.5 4.1 5.6 13.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TraT PF05818.12 CDJ58698.1 - 6.4 6.4 21.3 0.68 9.6 11.0 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF1764 PF08576.10 CDJ58698.1 - 6.5 7.7 17.7 3.4 8.6 10.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Peroxin-13_N PF04088.13 CDJ58698.1 - 9.5 6.5 15.5 3.2 8.0 0.8 2.1 1 1 1 2 2 2 0 Peroxin 13, N-terminal region MAT1 PF06391.13 CDJ58698.1 - 9.6 6.0 20.6 15 5.4 20.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF5327 PF17261.2 CDJ58698.1 - 9.9 7.0 27.5 8.9 7.1 16.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5327) Glycos_transf_1 PF00534.20 CDJ58699.1 - 0.0028 17.2 0.8 0.0028 17.2 0.8 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 TIP41 PF04176.13 CDJ58699.1 - 0.004 16.7 0.9 0.0065 16.0 0.9 1.3 1 0 0 1 1 1 1 TIP41-like family FAM176 PF14851.6 CDJ58699.1 - 0.87 9.2 7.6 0.91 9.2 6.4 1.6 2 0 0 2 2 2 0 FAM176 family Lin-8 PF03353.15 CDJ58699.1 - 1.2 8.7 15.5 0.15 11.6 7.2 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist AAA_23 PF13476.6 CDJ58700.1 - 0.0077 16.8 0.7 0.0077 16.8 0.7 9.5 9 3 1 10 10 10 1 AAA domain RSN1_TM PF13967.6 CDJ58700.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.8 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TMEM65 PF10507.9 CDJ58700.1 - 5.8 6.9 7.4 1.1e+02 2.8 0.0 5.9 3 0 0 3 3 3 0 Transmembrane protein 65 AIM3 PF17096.5 CDJ58701.1 - 0.0072 17.2 7.7 0.0072 17.2 7.7 20.2 4 3 2 6 6 6 1 Altered inheritance of mitochondria protein 3 Presenilin PF01080.17 CDJ58702.1 - 0.76 8.5 23.2 1 8.1 8.2 2.5 2 0 0 2 2 2 0 Presenilin ANAPC_CDC26 PF10471.9 CDJ58704.1 - 0.029 15.2 70.3 0.09 13.6 13.6 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 eIF-3_zeta PF05091.12 CDJ58704.1 - 0.033 13.2 22.9 0.065 12.2 11.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TMEM65 PF10507.9 CDJ58704.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.2 3 1 1 4 4 4 0 Transmembrane protein 65 DUF4834 PF16118.5 CDJ58704.1 - 0.37 11.8 33.7 2.3 9.3 4.6 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 CDJ58704.1 - 2.1 8.7 16.3 0.93 9.8 0.1 4.2 4 0 0 4 4 4 0 Orf78 (ac78) RskA PF10099.9 CDJ58705.1 - 9.6e-05 22.7 0.0 9.6e-05 22.7 0.0 10.1 5 4 1 7 7 7 3 Anti-sigma-K factor rskA CAF1 PF04857.20 CDJ58706.1 - 7.8e-58 196.1 5.7 7.8e-58 196.1 5.7 2.4 1 1 1 2 2 2 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 CDJ58706.1 - 0.012 15.3 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease OmpH PF03938.14 CDJ58706.1 - 0.98 9.8 40.5 0.8 10.0 22.4 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 CDJ58707.1 - 1.1e-07 32.4 0.7 0.0054 17.5 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ58707.1 - 3.1e-05 24.2 0.7 0.16 12.3 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 60KD_IMP PF02096.20 CDJ58707.1 - 0.006 16.5 1.4 0.016 15.1 1.5 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein NUC205 PF08168.11 CDJ58707.1 - 0.025 14.1 0.7 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 NUC205 domain Trp_oprn_chp PF09534.10 CDJ58707.1 - 0.034 13.9 19.8 0.15 11.8 9.4 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2232 PF09991.9 CDJ58707.1 - 0.76 8.9 4.8 1.3 8.1 4.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) LMBR1 PF04791.16 CDJ58707.1 - 0.8 8.5 4.3 1.3 7.9 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CHAD PF05235.14 CDJ58707.1 - 0.98 9.3 11.4 1.6 8.6 11.4 1.6 1 1 0 1 1 1 0 CHAD domain DUF1645 PF07816.11 CDJ58707.1 - 2.7 8.5 11.1 0.29 11.7 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) PorA PF11271.8 CDJ58707.1 - 7.3 5.8 20.5 3.7 6.8 3.7 2.1 2 0 0 2 2 2 0 Porin PorA TPR_14 PF13428.6 CDJ58708.1 - 0.00035 21.1 0.7 0.00035 21.1 0.7 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ58708.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 CDJ58708.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ58708.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SR-25 PF10500.9 CDJ58708.1 - 0.19 11.3 7.7 0.28 10.7 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 CDJ58708.1 - 3 5.9 4.5 3.9 5.5 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NICE-1 PF15845.5 CDJ58708.1 - 3.2 8.6 11.3 0.072 13.9 2.1 2.7 1 1 2 3 3 3 0 Cysteine-rich C-terminal 1 family Leu_Phe_trans PF03588.14 CDJ58710.1 - 8.8e-10 38.4 0.1 3.2e-09 36.5 0.0 2.0 3 0 0 3 3 3 1 Leucyl/phenylalanyl-tRNA protein transferase zf-B_box PF00643.24 CDJ58711.1 - 6.3e-12 45.5 13.1 2.1e-05 24.5 0.4 2.5 2 0 0 2 2 2 2 B-box zinc finger DUF3135 PF11333.8 CDJ58711.1 - 0.018 15.3 0.2 0.053 13.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PARP PF00644.20 CDJ58711.1 - 0.074 12.6 0.3 0.16 11.5 0.3 1.7 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain XPA_N PF01286.18 CDJ58711.1 - 3.7 7.7 7.1 4.7 7.3 0.1 3.4 3 0 0 3 3 3 0 XPA protein N-terminal Patched PF02460.18 CDJ58713.1 - 6.6e-90 302.3 0.0 1.9e-52 178.5 0.0 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDJ58713.1 - 1.9e-25 89.5 23.0 4.1e-24 85.2 1.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation UCR_6-4kD PF08997.10 CDJ58713.1 - 0.052 13.5 0.3 0.15 12.1 0.3 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein ACR_tran PF00873.19 CDJ58713.1 - 0.22 9.1 26.4 0.058 11.0 21.2 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family SUIM_assoc PF16619.5 CDJ58713.1 - 0.59 10.3 17.1 0.034 14.2 1.8 3.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Surface_antigen PF11054.8 CDJ58715.1 - 1.4e-12 47.8 1.8 2.3e-11 43.8 0.2 2.5 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ58716.1 - 3.8e-12 46.4 2.8 6.9e-12 45.6 1.6 1.9 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen Bindin PF02084.15 CDJ58716.1 - 6.1 7.0 14.5 2.9 8.1 11.9 1.7 1 1 0 1 1 1 0 Bindin PPP4R2 PF09184.11 CDJ58717.1 - 0.0028 17.3 1.5 0.0028 17.3 1.5 1.7 2 0 0 2 2 2 1 PPP4R2 MAGE_N PF12440.8 CDJ58717.1 - 0.0045 17.6 1.9 0.0045 17.6 1.9 7.1 5 3 3 8 8 8 1 Melanoma associated antigen family N terminal RNA_polI_A34 PF08208.11 CDJ58717.1 - 0.0054 16.8 2.9 0.012 15.7 2.9 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 MecA PF05389.12 CDJ58717.1 - 0.55 9.8 7.3 19 4.8 0.0 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Rgp1 PF08737.10 CDJ58717.1 - 0.71 9.0 5.9 3.5 6.7 3.5 2.2 2 0 0 2 2 2 0 Rgp1 MRP-S26 PF14943.6 CDJ58717.1 - 3.5 7.5 17.8 0.65 9.9 9.2 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Herpes_UL87 PF03043.14 CDJ58717.1 - 4.5 5.6 5.1 0.97 7.8 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL87 family HEAT PF02985.22 CDJ58718.1 - 0.4 11.1 3.5 1.9 8.9 0.1 4.2 2 0 0 2 2 2 0 HEAT repeat RskA PF10099.9 CDJ58718.1 - 1.1 9.6 0.0 0.18 12.1 16.5 9.7 3 2 3 6 6 6 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ58719.1 - 0.0014 17.6 9.4 0.0014 17.6 9.4 8.3 9 1 0 9 9 9 4 Protein of unknown function (DUF2722) AAA_2 PF07724.14 CDJ58720.1 - 6.3e-39 133.8 1.5 4.4e-37 127.8 0.4 3.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDJ58720.1 - 1.3e-24 86.1 0.2 3.9e-24 84.5 0.2 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CDJ58720.1 - 3.7e-21 75.9 0.1 2.1e-11 44.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ58720.1 - 2.7e-14 53.9 2.1 6.7e-07 29.8 0.1 3.8 3 1 0 3 3 2 2 AAA ATPase domain ClpB_D2-small PF10431.9 CDJ58720.1 - 4.2e-14 52.4 0.1 1.8e-13 50.3 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ58720.1 - 8.3e-12 45.3 0.7 4e-07 30.1 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDJ58720.1 - 8.8e-09 35.3 0.2 3.4e-06 26.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CDJ58720.1 - 9.1e-08 32.5 3.4 0.0057 16.9 0.1 4.8 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 CDJ58720.1 - 1.1e-06 28.7 0.0 0.064 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDJ58720.1 - 1.8e-06 28.6 0.0 0.032 14.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 CDJ58720.1 - 2.6e-06 26.9 0.0 0.0025 17.1 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin ATPase_2 PF01637.18 CDJ58720.1 - 1.6e-05 25.0 4.2 0.032 14.2 0.4 4.5 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDJ58720.1 - 2.2e-05 24.5 0.8 0.41 10.5 0.0 3.6 5 0 0 5 5 4 2 RsgA GTPase TniB PF05621.11 CDJ58720.1 - 3e-05 23.5 0.6 0.0092 15.4 0.1 3.7 3 1 0 3 3 2 1 Bacterial TniB protein RuvB_N PF05496.12 CDJ58720.1 - 4.7e-05 23.2 0.3 0.49 10.1 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDJ58720.1 - 5.3e-05 23.2 0.0 0.28 11.1 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 CDJ58720.1 - 5.7e-05 22.7 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ58720.1 - 9.6e-05 22.7 0.1 0.33 11.3 0.2 3.2 2 1 0 2 2 2 1 RNA helicase Torsin PF06309.11 CDJ58720.1 - 0.00014 21.9 0.0 0.00061 19.9 0.0 2.0 2 0 0 2 2 1 1 Torsin TsaE PF02367.17 CDJ58720.1 - 0.00021 21.3 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CDJ58720.1 - 0.00022 21.0 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Roc PF08477.13 CDJ58720.1 - 0.00033 20.9 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CDJ58720.1 - 0.00064 18.9 0.3 0.1 11.8 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 CDJ58720.1 - 0.00086 19.6 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CDJ58720.1 - 0.0023 17.2 4.6 2.3 7.3 0.1 3.6 3 1 1 4 4 3 2 TIP49 P-loop domain AAA_17 PF13207.6 CDJ58720.1 - 0.0031 17.9 1.0 1.8 9.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CDJ58720.1 - 0.0035 17.5 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 CDJ58720.1 - 0.0036 17.1 0.0 0.063 13.1 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 CDJ58720.1 - 0.0055 17.2 0.1 0.72 10.4 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 CDJ58720.1 - 0.0088 15.9 0.0 26 4.7 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_34 PF13872.6 CDJ58720.1 - 0.0092 14.9 0.0 0.18 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Mg_chelatase PF01078.21 CDJ58720.1 - 0.013 14.9 0.1 2.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 CDJ58720.1 - 0.018 14.9 0.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 CDJ58720.1 - 0.021 15.1 0.3 0.73 10.2 0.3 3.0 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 CDJ58720.1 - 0.032 14.2 4.3 1.3 9.0 0.0 4.2 3 2 1 5 5 4 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDJ58720.1 - 0.033 13.9 0.1 3 7.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CDJ58720.1 - 0.054 13.2 0.0 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CDJ58720.1 - 0.075 13.1 0.2 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain T2SSE PF00437.20 CDJ58720.1 - 0.082 11.9 0.0 0.48 9.4 0.0 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 CDJ58720.1 - 0.089 12.7 0.2 13 5.6 0.0 3.1 2 1 1 3 3 3 0 NTPase EIIBC-GUT_N PF03612.14 CDJ58721.1 - 0.65 9.7 3.0 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SbcD_C PF12320.8 CDJ58721.1 - 0.81 10.0 7.3 0.43 10.9 2.4 2.3 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain TFIIA PF03153.13 CDJ58721.1 - 1.2 9.0 25.1 0.36 10.8 8.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ58721.1 - 1.4 8.5 16.5 0.16 11.6 11.2 1.9 2 0 0 2 2 2 0 Spt20 family Rtf2 PF04641.12 CDJ58721.1 - 2.1 7.6 5.7 0.2 11.0 0.7 1.8 2 1 0 2 2 2 0 Rtf2 RING-finger DUF4611 PF15387.6 CDJ58722.1 - 0.00096 19.3 0.7 0.0016 18.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) TFIIA PF03153.13 CDJ58722.1 - 0.00099 19.2 18.3 0.0012 18.9 18.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ58722.1 - 0.011 15.3 14.5 0.015 14.9 14.5 1.2 1 0 0 1 1 1 0 Spt20 family PGA2 PF07543.12 CDJ58722.1 - 0.035 14.1 9.1 0.05 13.6 9.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF908 PF06012.12 CDJ58722.1 - 0.043 13.2 10.4 0.051 13.0 10.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF2052 PF09747.9 CDJ58722.1 - 0.08 13.1 7.3 0.11 12.6 7.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 CDJ58722.1 - 0.19 11.4 4.0 0.26 11.0 3.7 1.3 1 1 0 1 1 1 0 FAM176 family Nop53 PF07767.11 CDJ58722.1 - 1.4 8.3 14.8 1.8 7.9 14.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Virul_Fac PF10139.9 CDJ58722.1 - 1.4 7.0 11.9 1.9 6.6 11.9 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Hamartin PF04388.12 CDJ58722.1 - 2 7.0 10.4 2.4 6.7 10.4 1.1 1 0 0 1 1 1 0 Hamartin protein MRP-S31 PF15433.6 CDJ58722.1 - 2.9 7.5 10.1 3.6 7.2 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RR_TM4-6 PF06459.12 CDJ58722.1 - 3.1 7.5 9.8 4.5 7.0 9.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ58722.1 - 5.6 5.9 9.5 6.9 5.6 9.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 CDJ58722.1 - 6.3 5.4 15.5 8.2 5.0 15.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 CDJ58722.1 - 8.2 5.1 8.8 10 4.8 8.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 CDJ58722.1 - 8.7 6.3 6.2 11 5.9 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF382 PF04037.13 CDJ58723.1 - 1.2e-17 64.3 0.2 1.2e-17 64.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF382) SR-25 PF10500.9 CDJ58723.1 - 9.8e-05 22.1 10.3 9.8e-05 22.1 10.3 2.6 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF1860 PF08949.10 CDJ58723.1 - 0.052 13.3 0.1 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) BUD22 PF09073.10 CDJ58723.1 - 0.18 11.1 43.3 0.56 9.5 43.3 1.5 1 1 0 1 1 1 0 BUD22 Herpes_pp85 PF04637.12 CDJ58723.1 - 0.47 8.8 2.8 0.85 8.0 2.8 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF755 PF05501.11 CDJ58723.1 - 0.8 10.0 29.2 0.21 11.9 11.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Spt5_N PF11942.8 CDJ58723.1 - 2.5 9.1 37.8 1.2 10.2 9.9 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Prothymosin PF03247.14 CDJ58723.1 - 2.7 8.5 44.9 2.8 8.4 18.3 3.8 4 0 0 4 4 4 0 Prothymosin/parathymosin family RskA PF10099.9 CDJ58723.1 - 4 7.7 22.4 20 5.4 22.4 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF5423 PF17461.2 CDJ58723.1 - 5.5 5.7 18.3 0.078 11.8 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Ndc1_Nup PF09531.10 CDJ58723.1 - 7.8 5.1 9.7 4.1 6.0 0.7 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4614 PF15391.6 CDJ58723.1 - 9.3 6.2 17.6 0.1 12.6 5.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Mem_trans PF03547.18 CDJ58723.1 - 9.3 4.5 9.7 0.14 10.6 1.7 1.8 2 0 0 2 2 2 0 Membrane transport protein Helicase_C PF00271.31 CDJ58724.1 - 2.3e-27 95.5 0.0 2.3e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CDJ58724.1 - 5.2e-06 26.7 0.0 0.0013 18.9 0.0 3.0 1 1 0 1 1 1 1 GUCT (NUC152) domain TFIIA PF03153.13 CDJ58724.1 - 0.0079 16.2 16.8 0.08 12.9 5.2 2.6 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ58724.1 - 0.013 15.1 16.7 0.028 14.0 5.5 2.7 3 0 0 3 3 3 0 Spt20 family LIM_bind PF01803.16 CDJ58724.1 - 0.015 14.8 0.5 0.015 14.8 0.5 2.0 3 0 0 3 3 3 0 LIM-domain binding protein SUIM_assoc PF16619.5 CDJ58724.1 - 0.096 12.8 27.3 0.033 14.3 5.2 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 CDJ58724.1 - 0.16 10.9 9.6 0.28 10.1 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ctf8 PF09696.10 CDJ58724.1 - 0.92 9.8 8.8 2.3 8.5 2.3 2.9 3 0 0 3 3 3 0 Ctf8 RAB3GAP2_N PF14655.6 CDJ58724.1 - 5.1 6.2 8.4 0.11 11.8 0.5 2.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RNA_pol_Rpc4 PF05132.14 CDJ58724.1 - 8.9 6.7 9.3 6.5 7.2 0.6 3.8 4 0 0 4 4 4 0 RNA polymerase III RPC4 DNA_ligase_A_N PF04675.14 CDJ58725.1 - 4.6e-09 36.8 0.0 2.1e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 DNA ligase N terminus TFIIA PF03153.13 CDJ58726.1 - 0.018 15.1 22.0 0.021 14.8 22.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 CDJ58726.1 - 0.023 15.0 18.2 0.029 14.7 18.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ58726.1 - 0.092 9.9 14.1 0.095 9.8 14.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CDJ58726.1 - 0.13 11.6 7.8 0.17 11.3 7.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4746 PF15928.5 CDJ58726.1 - 0.18 11.2 17.3 0.29 10.5 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 CDJ58726.1 - 0.23 10.8 16.9 0.31 10.4 16.9 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 CDJ58726.1 - 0.51 8.4 12.2 0.65 8.0 12.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CCDC84 PF14968.6 CDJ58726.1 - 0.77 9.3 14.8 0.96 9.0 14.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 CCSAP PF15748.5 CDJ58726.1 - 0.85 9.7 20.8 1.2 9.2 20.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated WTX PF09422.10 CDJ58726.1 - 1.1 8.3 18.6 1.3 8.0 18.6 1.1 1 0 0 1 1 1 0 WTX protein RR_TM4-6 PF06459.12 CDJ58726.1 - 1.3 8.8 22.6 1.6 8.5 22.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ58726.1 - 1.8 6.7 14.6 2.3 6.4 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 CDJ58726.1 - 1.9 9.1 16.3 2.3 8.7 16.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Lin-8 PF03353.15 CDJ58726.1 - 1.9 7.9 20.8 2.6 7.5 20.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 CDJ58726.1 - 2.2 8.0 11.1 2.6 7.8 11.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LAP1C PF05609.12 CDJ58726.1 - 3.1 6.8 18.6 3.8 6.5 18.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3584 PF12128.8 CDJ58726.1 - 4 4.8 23.9 5.1 4.5 23.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 CDJ58726.1 - 4.1 6.1 19.0 4.9 5.8 19.0 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ58726.1 - 4.6 5.4 24.0 5.3 5.2 24.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CDJ58726.1 - 5 5.7 10.0 6.2 5.4 10.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2151 PF10221.9 CDJ58726.1 - 5 5.6 13.8 5.7 5.4 13.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3295 PF11702.8 CDJ58726.1 - 5.7 6.2 20.1 7 5.9 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF5427 PF10310.9 CDJ58726.1 - 8.2 5.3 23.2 11 4.9 23.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ABC_membrane PF00664.23 CDJ58727.1 - 5.2e-33 114.9 5.8 7.2e-33 114.4 5.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDJ58727.1 - 2.4e-29 102.6 0.1 6.9e-28 97.9 0.1 2.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDJ58727.1 - 1.3e-08 34.6 1.0 1.9e-05 24.2 0.1 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ58727.1 - 3.5e-05 24.1 0.8 0.064 13.5 0.8 2.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDJ58727.1 - 0.00036 20.2 0.5 0.017 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CDJ58727.1 - 0.00046 20.0 0.6 0.043 13.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 CDJ58727.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 CDJ58727.1 - 0.0014 19.1 7.3 0.0014 19.1 7.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDJ58727.1 - 0.003 17.3 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 CDJ58727.1 - 0.0083 15.6 4.8 12 5.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein Rad17 PF03215.15 CDJ58727.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 CDJ58727.1 - 0.017 15.0 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDJ58727.1 - 0.023 14.9 0.2 0.08 13.2 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CDJ58727.1 - 0.031 13.6 0.2 0.23 10.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 CDJ58727.1 - 0.031 14.0 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CDJ58727.1 - 0.033 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase APS_kinase PF01583.20 CDJ58727.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 CDJ58727.1 - 0.097 13.1 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDJ58727.1 - 0.4 10.8 4.7 1.1 9.5 2.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CDJ58727.1 - 0.67 9.6 1.8 1.9 8.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CDJ58727.1 - 1.2 9.6 7.4 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 CDJ58728.1 - 0.0044 16.0 21.6 0.072 12.0 7.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) OmpH PF03938.14 CDJ58728.1 - 0.043 14.2 19.8 0.14 12.5 5.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rnk_N PF14760.6 CDJ58728.1 - 0.11 13.0 0.1 0.35 11.4 0.1 1.9 1 0 0 1 1 1 0 Rnk N-terminus Zip PF02535.22 CDJ58728.1 - 0.59 9.3 1.7 2.9 7.0 0.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.14 CDJ58728.1 - 0.69 9.8 15.6 0.65 9.9 1.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 CDJ58728.1 - 2.8 7.9 11.3 5.4 7.0 3.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Spt20 PF12090.8 CDJ58728.1 - 4.1 6.9 40.5 0.015 14.9 8.7 2.5 2 1 0 2 2 2 0 Spt20 family Roughex PF06020.11 CDJ58728.1 - 7.7 5.5 18.6 4.4 6.3 4.0 2.2 2 0 0 2 2 2 0 Drosophila roughex protein SAE2 PF08573.10 CDJ58728.1 - 9 7.5 13.3 12 7.0 1.5 2.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus EGF_CA PF07645.15 CDJ58731.1 - 3e-223 721.9 535.4 6.8e-12 45.4 9.8 33.8 33 1 0 33 33 33 27 Calcium-binding EGF domain EGF_3 PF12947.7 CDJ58731.1 - 5.9e-152 493.5 545.0 2.5e-11 43.6 13.0 33.7 32 1 1 33 33 33 28 EGF domain cEGF PF12662.7 CDJ58731.1 - 1.4e-137 447.0 306.8 5.5e-08 32.6 3.2 31.4 31 0 0 31 31 31 29 Complement Clr-like EGF-like EGF PF00008.27 CDJ58731.1 - 9.4e-72 236.8 437.4 4.9e-05 23.5 7.5 32.2 32 0 0 32 32 32 29 EGF-like domain hEGF PF12661.7 CDJ58731.1 - 3.5e-71 233.6 342.5 2.6e-05 24.7 6.9 33.1 31 0 0 31 31 31 26 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDJ58731.1 - 1.7e-44 149.6 389.7 1.5e-06 28.2 3.4 32.2 31 0 0 31 31 31 23 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CDJ58731.1 - 3.2e-32 110.5 491.0 0.0019 18.5 9.6 32.4 30 2 1 31 31 31 25 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CDJ58731.1 - 1.6e-31 108.3 418.2 0.0021 18.3 4.5 31.6 30 2 1 31 31 31 26 Pvs28 EGF domain DUF4366 PF14283.6 CDJ58731.1 - 0.32 11.0 8.6 0.031 14.3 0.8 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) TMA7 PF09072.10 CDJ58732.1 - 8e-08 33.0 16.8 8e-08 33.0 16.8 1.7 2 0 0 2 2 2 1 Translation machinery associated TMA7 CTU2 PF10288.9 CDJ58732.1 - 0.053 13.8 0.2 0.059 13.6 0.2 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF2517 PF10725.9 CDJ58733.1 - 0.07 12.9 0.2 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) HasA PF06438.12 CDJ58734.1 - 0.0014 18.4 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Heme-binding protein A (HasA) DUF2706 PF10913.8 CDJ58734.1 - 0.045 13.6 0.2 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) C2 PF00168.30 CDJ58735.1 - 5.9e-35 119.7 0.0 4.2e-14 52.7 0.0 4.7 4 0 0 4 4 4 4 C2 domain Ferlin_C PF16165.5 CDJ58735.1 - 0.082 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus SF3b1 PF08920.10 CDJ58736.1 - 6.1e-27 94.5 18.6 1.7e-24 86.6 4.0 4.1 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT PF02985.22 CDJ58736.1 - 2.7e-08 33.4 6.4 1.3 9.5 0.1 8.1 8 0 0 8 8 8 2 HEAT repeat UME PF08064.13 CDJ58736.1 - 4.2e-05 23.4 1.0 10 6.1 0.0 5.3 5 1 0 5 5 5 1 UME (NUC010) domain Adaptin_N PF01602.20 CDJ58736.1 - 6.3e-05 21.7 0.7 0.17 10.4 0.0 3.8 3 1 1 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 CDJ58736.1 - 9.6e-05 22.8 11.2 0.29 11.7 0.0 6.3 7 1 1 8 8 7 2 HEAT-like repeat HEAT_2 PF13646.6 CDJ58736.1 - 0.0012 19.1 18.8 0.19 12.1 0.1 7.3 5 2 4 9 9 9 3 HEAT repeats Bep_C_terminal PF17841.1 CDJ58736.1 - 0.022 15.0 2.2 0.073 13.3 2.2 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) NUC173 PF08161.12 CDJ58736.1 - 0.025 14.2 0.0 3.6 7.2 0.0 3.9 3 1 1 4 4 4 0 NUC173 domain CLASP_N PF12348.8 CDJ58736.1 - 0.026 14.1 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.23 CDJ58736.1 - 0.074 13.1 3.3 72 3.6 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PsbH PF00737.20 CDJ58736.1 - 2.3 8.0 6.6 3.4 7.5 0.5 3.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein RskA PF10099.9 CDJ58737.1 - 0.086 13.1 4.7 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3395 PF11875.8 CDJ58738.1 - 3.1e-18 66.2 13.4 1.4e-17 64.0 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3395) DnaJ PF00226.31 CDJ58738.1 - 3.2e-16 59.2 0.0 8.2e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain GLTT PF01744.20 CDJ58739.1 - 0.0001 22.0 10.1 0.0018 18.0 2.7 2.3 1 1 1 2 2 2 2 GLTT repeat (6 copies) PAT1 PF09770.9 CDJ58739.1 - 0.0017 16.8 28.3 0.0024 16.2 28.3 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Zip PF02535.22 CDJ58739.1 - 0.24 10.6 7.4 0.075 12.2 4.4 1.6 1 1 1 2 2 2 0 ZIP Zinc transporter Pheromone PF08015.11 CDJ58739.1 - 0.25 12.4 7.4 0.14 13.3 2.4 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone O-antigen_lig PF13425.6 CDJ58739.1 - 1 8.1 4.1 1.8 7.3 4.1 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LMBR1 PF04791.16 CDJ58739.1 - 3 6.6 9.2 3.8 6.3 9.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein TRAP_alpha PF03896.16 CDJ58739.1 - 4.7 6.3 11.4 5.3 6.2 10.6 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.19 CDJ58740.1 - 0.0076 16.8 30.3 0.018 15.6 5.9 4.0 3 0 0 3 3 3 3 60s Acidic ribosomal protein Claudin_2 PF13903.6 CDJ58740.1 - 8.4 6.1 16.4 2.1 8.1 0.1 4.0 3 1 1 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Macoilin PF09726.9 CDJ58741.1 - 0.0031 16.2 51.1 0.0046 15.6 51.1 1.2 1 0 0 1 1 1 1 Macoilin family SR-25 PF10500.9 CDJ58741.1 - 0.08 12.5 73.1 2.6 7.6 41.4 3.0 1 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 CDJ58741.1 - 1.1 7.0 32.8 1.4 6.6 32.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Orbi_VP6 PF01516.16 CDJ58743.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF5524 PF17662.1 CDJ58743.1 - 0.79 9.0 7.4 0.033 13.6 0.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5524) SARAF PF06682.12 CDJ58744.1 - 0.00042 20.1 3.7 0.00042 20.1 3.7 6.5 2 2 3 6 6 6 1 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CDJ58744.1 - 0.00072 19.2 7.9 0.00072 19.2 7.9 10.1 5 2 2 7 7 7 2 Spt20 family SUIM_assoc PF16619.5 CDJ58744.1 - 0.014 15.5 1.5 0.014 15.5 1.5 17.0 7 4 6 13 13 13 0 Unstructured region C-term to UIM in Ataxin3 DUF1612 PF07756.12 CDJ58745.1 - 8.2 6.7 13.2 9.3 6.5 4.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Velvet PF11754.8 CDJ58746.1 - 0.0021 18.0 20.7 0.016 15.2 3.9 2.3 2 0 0 2 2 2 2 Velvet factor Tim54 PF11711.8 CDJ58746.1 - 2.2 7.0 19.2 0.58 8.9 3.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 CDJ58746.1 - 2.3 7.5 29.2 0.71 9.2 9.3 2.2 2 0 0 2 2 2 0 FAM76 protein SpoIIP PF07454.11 CDJ58746.1 - 3 7.2 22.0 0.67 9.4 4.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CDJ58746.1 - 3.9 6.8 27.5 5.7 6.3 8.9 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Band_3_cyto PF07565.13 CDJ58746.1 - 4.6 7.0 28.1 0.57 9.9 10.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Lin-8 PF03353.15 CDJ58746.1 - 7.3 6.1 30.6 0.45 10.0 8.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist AMP-binding PF00501.28 CDJ58747.1 - 2.3e-56 191.2 0.0 3.7e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme SUIM_assoc PF16619.5 CDJ58747.1 - 0.042 13.9 16.1 0.67 10.1 2.7 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Takusan PF04822.13 CDJ58749.1 - 0.0028 17.5 0.5 0.0028 17.5 0.5 3.0 3 0 0 3 3 3 1 Takusan baeRF_family10 PF18854.1 CDJ58749.1 - 0.61 10.3 13.0 0.15 12.3 4.4 2.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF2208 PF09973.9 CDJ58750.1 - 0.31 10.6 0.4 0.52 9.9 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Nucleoporin_FG PF13634.6 CDJ58751.1 - 1.7e-07 32.0 79.2 8.3e-06 26.6 36.6 11.3 8 3 6 14 14 14 3 Nucleoporin FG repeat region SUIM_assoc PF16619.5 CDJ58752.1 - 0.011 15.8 5.3 0.011 15.8 5.3 16.5 7 5 5 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 CBF PF03914.17 CDJ58753.1 - 4.8e-15 56.0 0.9 4.8e-15 56.0 0.9 5.4 5 2 2 7 7 7 2 CBF/Mak21 family Caprin-1_dimer PF18293.1 CDJ58755.1 - 0.0014 19.1 0.9 0.0026 18.3 0.9 1.3 1 0 0 1 1 1 1 Caprin-1 dimerization domain POX PF07526.11 CDJ58755.1 - 0.0069 17.0 3.9 0.013 16.0 3.9 1.6 1 0 0 1 1 1 1 Associated with HOX WDCP PF15390.6 CDJ58755.1 - 0.05 12.0 5.1 0.058 11.8 5.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Menin PF05053.13 CDJ58755.1 - 0.097 11.0 9.1 0.12 10.7 9.1 1.1 1 0 0 1 1 1 0 Menin Corona_nucleoca PF00937.18 CDJ58755.1 - 0.11 11.5 16.1 0.14 11.1 16.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Apt1 PF10351.9 CDJ58755.1 - 0.14 11.0 14.9 0.18 10.6 14.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ58755.1 - 0.56 8.7 16.2 0.75 8.3 16.2 1.2 1 0 0 1 1 1 0 Macoilin family AF-4 PF05110.13 CDJ58755.1 - 1.7 6.7 26.6 2.2 6.3 26.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PA26 PF04636.13 CDJ58755.1 - 2.3 7.1 6.1 2.9 6.7 6.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RPS31 PF17067.5 CDJ58755.1 - 4.3 7.6 15.3 3.3 7.9 13.8 1.5 1 1 0 1 1 1 0 Ribosomal protein S31e SARAF PF06682.12 CDJ58755.1 - 4.6 6.8 11.4 0.17 11.5 5.8 1.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 CDJ58755.1 - 6.5 5.3 15.3 8.3 5.0 15.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC106 PF15794.5 CDJ58755.1 - 9.7 5.8 15.4 15 5.2 15.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Radical_SAM PF04055.21 CDJ58756.1 - 0.00078 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF4667 PF15700.5 CDJ58756.1 - 0.078 13.1 3.3 0.1 12.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) NBD_C PF17042.5 CDJ58756.1 - 0.098 13.2 6.1 0.063 13.8 2.4 2.2 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain SR-25 PF10500.9 CDJ58756.1 - 0.97 9.0 10.9 1.4 8.5 10.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VWA_2 PF13519.6 CDJ58757.1 - 3.3 8.4 5.3 3.4 8.3 0.1 3.2 1 1 2 3 3 3 0 von Willebrand factor type A domain CAP_N PF01213.19 CDJ58759.1 - 0.007 15.9 6.5 0.0074 15.8 6.5 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDJ58759.1 - 0.28 11.2 4.9 0.3 11.1 4.9 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 CDJ58759.1 - 0.37 10.8 0.8 0.34 10.9 0.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2076 PF09849.9 CDJ58759.1 - 0.43 10.6 9.7 0.45 10.5 9.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) AAA_23 PF13476.6 CDJ58760.1 - 9.2e-05 23.0 19.1 0.0082 16.7 0.7 2.3 2 0 0 2 2 2 2 AAA domain RskA PF10099.9 CDJ58760.1 - 0.0016 18.7 4.6 0.0025 18.1 2.4 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Halogen_Hydrol PF10112.9 CDJ58760.1 - 0.0017 18.4 0.2 0.0017 18.4 0.2 2.4 2 0 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein Tmemb_cc2 PF10267.9 CDJ58760.1 - 0.0084 15.3 24.8 0.013 14.7 24.8 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF521 PF04412.13 CDJ58760.1 - 0.019 13.7 4.1 0.029 13.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) PAS PF00989.25 CDJ58760.1 - 0.081 12.9 2.4 0.24 11.4 2.4 1.7 1 0 0 1 1 1 0 PAS fold LMBR1 PF04791.16 CDJ58760.1 - 0.13 11.2 9.0 0.2 10.6 9.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF572 PF04502.13 CDJ58760.1 - 0.36 10.4 23.1 0.53 9.8 23.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Transglut_prok PF09017.10 CDJ58760.1 - 0.49 9.7 6.6 0.75 9.1 6.6 1.2 1 0 0 1 1 1 0 Microbial transglutaminase FAM199X PF15814.5 CDJ58760.1 - 0.79 8.7 14.5 1.4 7.9 14.5 1.3 1 0 0 1 1 1 0 Protein family FAM199X Roughex PF06020.11 CDJ58760.1 - 0.95 8.5 12.6 1.8 7.6 12.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein GREB1 PF15782.5 CDJ58760.1 - 1 6.4 19.4 1.2 6.2 19.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spore_coat_CotO PF14153.6 CDJ58760.1 - 2.2 8.2 25.6 0.2 11.6 17.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SSPI PF14098.6 CDJ58760.1 - 2.2 8.5 7.2 1.7 8.9 2.4 2.7 2 0 0 2 2 2 0 Small, acid-soluble spore protein I DUF3537 PF12056.8 CDJ58760.1 - 2.3 7.0 8.7 4 6.2 8.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SMYLE_N PF18615.1 CDJ58760.1 - 3.8 7.0 17.2 2.2 7.8 13.7 1.9 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain AAT PF03417.16 CDJ58760.1 - 5.4 6.6 12.5 0.37 10.4 7.4 1.6 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase OATP PF03137.20 CDJ58760.1 - 7.9 4.6 7.3 23 3.1 0.0 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family OmpH PF03938.14 CDJ58760.1 - 8.6 6.7 38.2 11 6.4 6.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Roughex PF06020.11 CDJ58761.1 - 1.3 8.0 13.5 2.5 7.1 13.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Plasmodium_Vir PF05795.11 CDJ58761.1 - 9.2 5.6 15.8 1.4 8.2 12.1 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ribosomal_60s PF00428.19 CDJ58762.1 - 0.0048 17.5 6.6 0.0048 17.5 6.6 4.4 3 1 1 4 4 4 1 60s Acidic ribosomal protein Ecl1 PF12855.7 CDJ58762.1 - 1.3 10.2 47.8 6.5 7.9 15.4 2.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Glyco_transf_5 PF08323.11 CDJ58764.1 - 7.5e-08 32.4 1.1 1.3e-05 25.0 1.1 2.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 CDJ58764.1 - 1.9e-07 31.3 0.0 5.6e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 CBM_48 PF02922.18 CDJ58764.1 - 4.8e-07 30.0 0.0 4.2e-06 27.0 0.0 2.3 1 1 1 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDJ58764.1 - 6.4e-07 29.3 0.0 1.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_trans_4_4 PF13579.6 CDJ58764.1 - 9.9e-07 29.3 6.1 4.7e-06 27.1 0.0 4.0 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 CDJ58765.1 - 2.9e-36 124.6 0.0 4.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ58765.1 - 8.5e-28 97.4 0.0 1.8e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase_C PF02806.18 CDJ58765.1 - 9.7e-15 54.8 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_transf_4 PF13439.6 CDJ58765.1 - 1.2e-12 48.1 0.1 1.1e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDJ58765.1 - 1.3e-07 32.2 0.0 4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CDJ58765.1 - 0.0018 18.6 0.0 0.0031 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Poxvirus_B22R_N PF13169.6 CDJ58765.1 - 0.16 12.5 0.1 0.32 11.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal TTL PF03133.15 CDJ58766.1 - 0.014 14.6 1.8 0.019 14.1 0.0 1.9 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATG101 PF07855.12 CDJ58766.1 - 0.026 14.5 0.6 3.1 7.8 0.6 2.5 1 1 0 1 1 1 0 Autophagy-related protein 101 SR-25 PF10500.9 CDJ58766.1 - 0.39 10.3 13.4 0.09 12.4 9.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ58766.1 - 0.92 9.1 17.5 0.11 12.1 3.0 2.1 2 0 0 2 2 2 0 Spt20 family E1-N PF14463.6 CDJ58768.1 - 0.013 15.4 1.2 0.025 14.4 1.2 1.5 1 0 0 1 1 1 0 E1 N-terminal domain PWI PF01480.17 CDJ58768.1 - 0.017 15.4 0.1 0.017 15.4 0.1 1.9 2 0 0 2 2 2 0 PWI domain DEDD_Tnp_IS110 PF01548.17 CDJ58768.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Transposase Activator_LAG-3 PF11498.8 CDJ58768.1 - 0.21 10.5 44.4 0.16 10.9 35.3 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.9 CDJ58771.1 - 3.9 7.0 11.6 8.5 5.9 11.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PCI PF01399.27 CDJ58772.1 - 1.1e-11 45.2 1.6 1.2e-11 45.0 0.2 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CDJ58772.1 - 0.13 12.5 2.6 0.65 10.3 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 CDJ58773.1 - 0.14 12.4 3.2 0.32 11.3 1.4 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Titin_Z PF09042.11 CDJ58773.1 - 0.33 10.9 6.2 4.4 7.3 4.8 2.3 2 0 0 2 2 2 0 Titin Z RPN1_RPN2_N PF17781.1 CDJ58774.1 - 2.1e-99 332.8 0.0 1.6e-75 254.4 0.0 2.3 1 1 1 2 2 2 2 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDJ58774.1 - 3.7e-27 94.1 0.0 8e-27 93.0 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDJ58774.1 - 2.5e-12 46.6 34.4 0.00027 21.2 0.2 8.7 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDJ58774.1 - 0.044 14.2 9.5 0.12 12.8 0.1 4.5 4 2 1 5 5 5 0 HEAT repeats Mucin PF01456.17 CDJ58774.1 - 0.078 13.0 9.8 1.6 8.8 0.4 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein PI3_PI4_kinase PF00454.27 CDJ58776.1 - 2e-33 116.2 0.0 3.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SHMT PF00464.19 CDJ58777.1 - 5.1e-171 568.7 0.0 5.9e-171 568.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase zf-C2H2_12 PF18658.1 CDJ58777.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type PglZ PF08665.12 CDJ58779.1 - 1.3 9.1 6.0 0.88 9.6 1.8 2.4 2 1 1 3 3 3 0 PglZ domain LANC_like PF05147.13 CDJ58780.1 - 4.2e-10 38.7 0.8 0.00055 18.6 0.1 3.1 2 1 1 3 3 3 3 Lanthionine synthetase C-like protein DUF755 PF05501.11 CDJ58781.1 - 0.0064 16.8 18.1 0.0064 16.8 18.1 7.7 7 1 1 8 8 8 1 Domain of unknown function (DUF755) RskA PF10099.9 CDJ58781.1 - 0.011 16.0 17.7 0.011 16.0 17.7 9.4 4 2 2 6 6 6 0 Anti-sigma-K factor rskA MAR_sialic_bdg PF10564.9 CDJ58782.1 - 2.3e-47 158.9 17.7 5.8e-28 96.8 2.6 3.3 3 0 0 3 3 3 3 Sialic-acid binding micronemal adhesive repeat GARS_A PF01071.19 CDJ58783.1 - 0.041 13.6 0.3 0.15 11.8 0.3 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MAR_sialic_bdg PF10564.9 CDJ58785.1 - 1.3e-21 76.5 0.9 1.6e-21 76.1 0.9 1.1 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat BRO1 PF03097.18 CDJ58787.1 - 1.8e-31 109.3 1.6 1.5e-30 106.3 0.0 2.4 2 0 0 2 2 2 1 BRO1-like domain FKBP_N PF01346.18 CDJ58788.1 - 0.41 11.6 4.2 8.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pro_isomerase PF00160.21 CDJ58789.1 - 6.1e-35 120.8 0.0 2e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CLAMP PF14769.6 CDJ58790.1 - 1.3e-13 51.2 0.1 2.2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 NRDE-2 PF08424.10 CDJ58790.1 - 0.17 11.0 1.4 0.31 10.1 1.4 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference AAA_2 PF07724.14 CDJ58791.1 - 5.7e-30 104.7 0.0 1.3e-29 103.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDJ58791.1 - 2.1e-06 28.2 0.0 3.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDJ58791.1 - 0.0037 17.3 0.1 0.013 15.6 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein DnaA_N PF11638.8 CDJ58791.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 DnaA N-terminal domain DNA_pol_B PF00136.21 CDJ58792.1 - 5.2e-23 81.5 0.0 6.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 CDJ58792.1 - 3.9e-18 65.7 5.7 6.5e-18 65.0 5.7 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta ParB_C PF18064.1 CDJ58792.1 - 0.15 12.2 1.5 0.37 11.0 1.4 1.7 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal zf-RING-like PF08746.11 CDJ58792.1 - 0.7 10.3 8.7 0.31 11.4 0.5 2.4 2 0 0 2 2 2 0 RING-like domain C6_DPF PF10170.9 CDJ58792.1 - 0.84 10.0 5.1 0.71 10.3 0.3 2.3 1 1 0 2 2 2 0 Cysteine-rich domain AAA_2 PF07724.14 CDJ58793.1 - 8.4e-38 130.2 0.0 1.4e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CDJ58793.1 - 7.7e-13 48.3 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDJ58793.1 - 1.8e-08 34.5 0.0 2.1e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CDJ58793.1 - 1.6e-07 31.8 0.0 3.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDJ58793.1 - 8.4e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ58793.1 - 0.00032 20.1 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Torsin PF06309.11 CDJ58793.1 - 0.0028 17.7 0.9 0.0041 17.2 0.0 1.7 2 0 0 2 2 1 1 Torsin RuvB_N PF05496.12 CDJ58793.1 - 0.0045 16.8 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ58793.1 - 0.01 16.2 0.4 0.36 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 CDJ58793.1 - 0.021 15.4 0.0 0.057 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDJ58793.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CDJ58793.1 - 0.073 13.3 2.3 1.3 9.3 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDJ58793.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDJ58793.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 CDJ58793.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CDJ58793.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 CDJ58793.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 CDJ58793.1 - 0.2 12.0 0.1 0.58 10.6 0.1 2.0 1 1 0 1 1 1 0 RNA helicase Ins145_P3_rec PF08709.11 CDJ58794.1 - 0.022 14.0 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor TF_Zn_Ribbon PF08271.12 CDJ58796.1 - 0.00021 20.7 11.3 0.24 10.9 0.2 5.0 5 0 0 5 5 5 2 TFIIB zinc-binding zf_C2H2_13 PF18508.1 CDJ58796.1 - 0.00071 19.1 3.4 1.6 8.4 0.1 4.4 4 0 0 4 4 4 1 Zinc finger domain CmcI PF04989.12 CDJ58796.1 - 0.064 12.9 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase HipA_C PF07804.12 CDJ58796.1 - 0.11 12.2 4.7 3.7 7.2 0.0 4.1 2 2 1 4 4 4 0 HipA-like C-terminal domain Sigma70_r2 PF04542.14 CDJ58796.1 - 1.6 8.5 6.1 8.4 6.2 0.0 4.5 6 0 0 6 6 6 0 Sigma-70 region 2 zf-CHY PF05495.12 CDJ58796.1 - 2.3 8.8 18.7 0.74 10.3 6.8 3.6 3 1 1 4 4 4 0 CHY zinc finger Mut7-C PF01927.16 CDJ58796.1 - 3.5 7.7 10.0 2.4 8.3 2.4 3.1 2 1 1 3 3 3 0 Mut7-C RNAse domain TMEM132D_C PF15706.5 CDJ58797.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Enkurin PF13864.6 CDJ58799.1 - 5.8e-05 23.5 1.3 9.4e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Calmodulin-binding CAP PF00188.26 CDJ58800.1 - 1.1e-09 39.1 1.7 1.6e-09 38.7 1.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RskA PF10099.9 CDJ58801.1 - 0.00051 20.4 0.0 0.00051 20.4 0.0 12.3 6 4 3 9 9 9 2 Anti-sigma-K factor rskA Vps26 PF03643.15 CDJ58802.1 - 1.4e-106 355.5 1.2 1.6e-106 355.3 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CDJ58802.1 - 0.064 13.7 0.1 0.37 11.3 0.1 2.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain ASH PF15780.5 CDJ58805.1 - 9.6e-10 38.6 0.1 0.003 17.7 0.0 3.1 2 1 1 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CDJ58805.1 - 2.3e-05 24.5 0.1 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein 131-like PapD-like PF14874.6 CDJ58805.1 - 0.16 12.1 1.0 1.2 9.3 0.0 2.9 4 0 0 4 4 4 0 Flagellar-associated PapD-like IMUP PF15761.5 CDJ58806.1 - 0.014 16.1 7.5 0.014 16.1 7.5 6.9 5 3 1 6 6 6 0 Immortalisation up-regulated protein WD40 PF00400.32 CDJ58807.1 - 9e-11 42.2 12.2 0.0072 17.2 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ATP-synt_C PF00137.21 CDJ58808.1 - 6.6e-31 106.4 33.2 3.4e-19 68.9 14.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PanZ PF12568.8 CDJ58809.1 - 4.9e-05 23.1 0.1 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_10 PF13673.7 CDJ58809.1 - 0.00015 21.7 0.1 0.0032 17.4 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ58809.1 - 0.00016 22.0 0.0 0.00047 20.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ58809.1 - 0.00078 19.7 0.9 0.0044 17.2 0.1 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDJ58809.1 - 0.12 12.4 0.2 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein RecX PF02631.16 CDJ58809.1 - 0.82 10.1 0.0 0.82 10.1 0.0 2.5 2 1 0 2 2 2 0 RecX family Cpn60_TCP1 PF00118.24 CDJ58810.1 - 3.2e-33 115.1 1.6 3.5e-33 115.0 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PPTA PF01239.22 CDJ58811.1 - 1.6e-09 37.1 2.8 6.2e-07 28.9 1.3 2.5 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat Suf PF05843.14 CDJ58811.1 - 1 9.3 12.3 8.2 6.3 12.3 1.9 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3391 PF11871.8 CDJ58811.1 - 3.2 8.3 8.2 29 5.2 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Spt20 PF12090.8 CDJ58811.1 - 3.4 7.2 12.9 0.78 9.3 8.1 1.9 2 0 0 2 2 2 0 Spt20 family ABC_tran PF00005.27 CDJ58812.1 - 2.4e-16 60.5 0.4 9.5e-16 58.6 0.4 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ58812.1 - 3e-06 27.3 0.1 0.024 14.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ58812.1 - 0.041 13.6 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ58812.1 - 0.051 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CDJ58812.1 - 0.068 13.7 0.1 0.16 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 CDJ58812.1 - 0.086 12.5 0.4 0.15 11.7 0.4 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Ribosomal_60s PF00428.19 CDJ58813.1 - 0.28 11.8 10.2 0.9 10.2 3.1 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein UreF PF01730.16 CDJ58813.1 - 0.31 11.6 16.9 0.37 11.4 3.0 4.1 3 1 1 4 4 4 0 UreF Pilus_CpaD PF09476.10 CDJ58813.1 - 6.6 6.4 11.1 0.17 11.6 0.9 2.4 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) CLN3 PF02487.17 CDJ58814.1 - 0.96 8.4 10.1 2 7.3 10.1 1.6 1 0 0 1 1 1 0 CLN3 protein GAGA_bind PF06217.12 CDJ58814.1 - 9.6 6.4 24.2 19 5.4 24.2 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1645 PF07816.11 CDJ58815.1 - 4.3e-05 24.2 6.2 4.3e-05 24.2 6.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) PAP1 PF08601.10 CDJ58815.1 - 0.00062 19.6 9.3 0.0014 18.5 9.2 1.6 1 1 0 1 1 1 1 Transcription factor PAP1 CobT PF06213.12 CDJ58815.1 - 0.0045 16.4 15.7 0.0045 16.4 15.7 2.2 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT RskA PF10099.9 CDJ58815.1 - 0.012 15.9 9.8 0.26 11.5 0.1 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PTPRCAP PF15713.5 CDJ58815.1 - 0.02 15.2 15.5 0.056 13.7 9.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Connexin PF00029.19 CDJ58815.1 - 0.028 14.2 13.4 0.088 12.5 6.8 2.2 2 0 0 2 2 2 0 Connexin Peptidase_S49_N PF08496.10 CDJ58815.1 - 0.028 14.5 20.5 0.031 14.4 9.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2052 PF09747.9 CDJ58815.1 - 0.16 12.1 21.0 0.1 12.7 11.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) OATP PF03137.20 CDJ58815.1 - 0.41 8.9 7.8 1.8 6.7 4.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 CDJ58815.1 - 0.71 8.4 6.0 1.5 7.3 0.1 2.1 2 0 0 2 2 2 0 AMP-binding enzyme Tim54 PF11711.8 CDJ58815.1 - 0.73 8.6 16.1 0.52 9.0 8.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Peptidase_U57 PF05582.12 CDJ58815.1 - 0.87 8.8 15.6 2.2 7.5 1.7 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Bacteriocin_IIc PF10439.9 CDJ58815.1 - 0.89 9.7 14.1 0.22 11.7 10.1 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Vfa1 PF08432.10 CDJ58815.1 - 1.2 9.5 23.7 0.15 12.4 10.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DNApol_Exo PF18136.1 CDJ58815.1 - 1.2 8.2 18.4 0.49 9.5 2.8 2.1 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DUF3169 PF11368.8 CDJ58815.1 - 1.6 8.2 0.0 1.6 8.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) Lin-8 PF03353.15 CDJ58815.1 - 2.7 7.5 32.6 0.19 11.2 20.5 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CDJ58815.1 - 3.2 6.4 26.9 4.3 6.0 0.8 2.1 2 0 0 2 2 2 0 Presenilin DUF4666 PF15697.5 CDJ58815.1 - 3.3 8.5 20.7 3.1 8.5 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) AIF_C PF14721.6 CDJ58815.1 - 3.4 8.0 17.8 0.4 11.0 6.0 2.6 3 1 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Adaptin_binding PF10199.9 CDJ58815.1 - 4.2 8.0 19.6 1.7 9.2 11.8 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF2232 PF09991.9 CDJ58815.1 - 4.4 6.4 5.3 7.3 5.7 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2232) FAM176 PF14851.6 CDJ58815.1 - 5 6.8 16.6 5.1 6.7 7.7 2.4 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 CDJ58815.1 - 5 7.0 21.2 0.38 10.6 9.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 CDJ58815.1 - 5.2 6.2 6.5 8.7 5.4 4.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SpoIIP PF07454.11 CDJ58815.1 - 5.2 6.4 22.5 0.54 9.7 13.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Ureide_permease PF07168.11 CDJ58815.1 - 5.3 5.7 8.7 13 4.4 0.1 2.2 2 0 0 2 2 2 0 Ureide permease DNA_pol_delta_4 PF04081.13 CDJ58815.1 - 6.2 7.2 22.1 1.5 9.1 3.0 2.2 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 V_ATPase_I PF01496.19 CDJ58815.1 - 6.3 4.6 25.9 1.2 7.0 12.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Afi1 PF07792.12 CDJ58815.1 - 6.3 7.3 17.8 7.8 7.0 10.6 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 CDJ58815.1 - 6.7 6.5 25.3 0.39 10.5 12.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1764 PF08576.10 CDJ58815.1 - 6.8 7.7 20.6 11 7.0 11.4 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) eIF3_subunit PF08597.10 CDJ58815.1 - 8.2 6.3 24.6 0.43 10.5 10.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit eIF-3_zeta PF05091.12 CDJ58815.1 - 8.6 5.2 24.1 0.94 8.4 12.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-A20 PF01754.16 CDJ58816.1 - 8.4e-12 44.8 7.3 8.4e-12 44.8 7.3 2.5 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.16 CDJ58816.1 - 6.5e-08 32.6 8.2 6.5e-08 32.6 8.2 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger TFIIA PF03153.13 CDJ58816.1 - 1 9.3 6.1 1.1 9.1 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUP50 PF08911.11 CDJ58817.1 - 0.0026 18.4 7.5 0.0064 17.1 6.9 2.1 1 1 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) TFIID_30kDa PF03540.13 CDJ58819.1 - 7e-06 25.9 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Prefoldin PF02996.17 CDJ58820.1 - 4.4e-21 75.0 5.6 6.5e-21 74.5 5.6 1.3 1 0 0 1 1 1 1 Prefoldin subunit eIF-4B PF06273.11 CDJ58820.1 - 0.0023 17.1 0.8 0.003 16.7 0.8 1.2 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B Vac17 PF17321.2 CDJ58820.1 - 0.019 14.4 1.0 0.019 14.4 1.0 1.8 3 0 0 3 3 3 0 Vacuole-related protein 17 PKHD_C PF18331.1 CDJ58820.1 - 0.027 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Nsp1_C PF05064.13 CDJ58820.1 - 0.036 13.9 1.4 0.036 13.9 1.4 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region TMPIT PF07851.13 CDJ58820.1 - 0.038 13.3 0.2 0.038 13.3 0.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein CHDCT2 PF08074.11 CDJ58820.1 - 0.39 10.9 3.7 3.3 7.8 0.3 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF3120 PF11318.8 CDJ58822.1 - 0.02 15.2 0.2 0.038 14.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) FIST PF08495.10 CDJ58823.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FIST N domain RCC1 PF00415.18 CDJ58826.1 - 8.8e-51 170.3 29.5 1e-13 51.7 0.8 7.1 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ58826.1 - 1.3e-30 104.5 42.5 3e-09 36.4 1.5 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CDJ58826.1 - 8.2e-06 25.7 0.1 3.1 7.4 0.0 4.0 4 0 0 4 4 4 3 TUP1-like enhancer of split Kelch_2 PF07646.15 CDJ58826.1 - 0.0011 18.8 0.2 29 4.8 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDJ58826.1 - 0.16 12.0 1.0 20 5.3 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Ribosomal_L5e PF17144.4 CDJ58827.1 - 4e-80 267.6 0.6 4e-80 267.6 0.6 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDJ58827.1 - 1.2e-31 109.5 6.7 1.2e-31 109.5 6.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Choline_sulf_C PF12411.8 CDJ58827.1 - 0.074 12.9 0.7 7.4 6.5 0.1 2.7 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal VitK2_biosynth PF02621.14 CDJ58827.1 - 0.27 10.7 1.4 0.48 9.9 1.4 1.5 1 0 0 1 1 1 0 Menaquinone biosynthesis Anticodon_1 PF08264.13 CDJ58828.1 - 1.1e-28 100.2 0.1 2.2e-27 95.9 0.1 2.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 CDJ58828.1 - 1.5e-05 25.2 6.2 3e-05 24.2 6.2 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Mito_fiss_reg PF05308.11 CDJ58828.1 - 0.025 14.6 1.4 0.043 13.9 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Enkurin PF13864.6 CDJ58828.1 - 0.18 12.3 6.7 1.2 9.6 5.2 2.8 2 1 0 2 2 2 0 Calmodulin-binding bZIP_2 PF07716.15 CDJ58828.1 - 5.1 7.3 6.6 0.42 10.7 0.5 2.3 3 0 0 3 3 3 0 Basic region leucine zipper DUF4179 PF13786.6 CDJ58829.1 - 0.045 14.2 9.4 1.6 9.2 0.4 4.8 3 2 2 5 5 5 0 Domain of unknown function (DUF4179) ketoacyl-synt PF00109.26 CDJ58830.1 - 1.8e-63 214.5 0.0 8e-63 212.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ58830.1 - 9.3e-46 156.0 0.1 4.2e-45 153.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 CDJ58830.1 - 2.8e-30 104.7 0.2 7.3e-30 103.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 CDJ58830.1 - 5e-29 101.3 0.0 9.3e-27 93.8 0.0 2.8 3 0 0 3 3 3 1 Male sterility protein PP-binding PF00550.25 CDJ58830.1 - 3.9e-10 39.9 0.6 1.2e-09 38.4 0.6 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CDJ58830.1 - 6.9e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.21 CDJ58830.1 - 1.4e-08 34.6 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short_C2 PF13561.6 CDJ58830.1 - 2e-07 30.8 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CDJ58830.1 - 1.9e-05 23.9 0.0 0.00015 21.0 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CDJ58830.1 - 5.9e-05 22.6 0.3 0.017 14.6 0.0 3.3 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ58830.1 - 0.028 13.8 0.0 0.08 12.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TPR_19 PF14559.6 CDJ58831.1 - 0.0013 19.2 3.8 0.0082 16.6 1.2 13.3 12 3 4 16 16 16 5 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ58831.1 - 0.13 12.9 0.2 0.13 12.9 0.2 13.8 12 2 1 13 13 13 0 Tetratricopeptide repeat SulA PF03846.14 CDJ58831.1 - 0.18 11.8 6.8 0.077 12.9 2.5 2.8 2 0 0 2 2 2 0 Cell division inhibitor SulA Ldt_C PF17969.1 CDJ58831.1 - 0.73 10.6 2.6 3.4 8.5 2.6 2.2 1 0 0 1 1 1 0 L,D-transpeptidase C-terminal domain Tcf25 PF04910.14 CDJ58831.1 - 9.9 5.1 10.3 0.23 10.5 1.2 2.8 3 0 0 3 3 3 0 Transcriptional repressor TCF25 Ephrin_rec_like PF07699.13 CDJ58832.1 - 0.0037 17.0 6.8 0.0037 17.0 6.8 5.4 2 1 3 5 5 5 4 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ58834.1 - 4.3e-06 26.4 14.0 3.8e-05 23.3 2.4 5.5 3 1 2 5 5 5 2 Putative ephrin-receptor like Lustrin_cystein PF14625.6 CDJ58834.1 - 0.28 11.6 47.1 0.24 11.8 3.1 7.1 4 3 3 7 7 7 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 CDJ58835.1 - 3.8e-11 42.6 25.4 3.9e-06 26.5 0.8 4.4 3 1 1 4 4 4 3 Putative ephrin-receptor like PCI PF01399.27 CDJ58836.1 - 0.14 12.7 0.0 1.7 9.2 0.0 2.0 1 1 1 2 2 2 0 PCI domain NPV_P10 PF05531.12 CDJ58836.1 - 0.34 11.4 1.8 3.2 8.3 0.2 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein eIF3g PF12353.8 CDJ58838.1 - 9e-13 48.7 9.6 1.6e-11 44.7 9.6 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Helicase_RecD PF05127.14 CDJ58840.1 - 6.1e-56 189.0 0.0 6.1e-56 189.0 0.0 3.2 4 2 1 5 5 5 1 Helicase PCMT PF01135.19 CDJ58840.1 - 1.4e-51 175.2 1.0 2.9e-46 157.9 0.2 3.4 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDJ58840.1 - 0.00066 19.5 0.4 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ58840.1 - 0.12 13.1 0.1 0.54 11.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ58840.1 - 0.18 11.6 5.0 2 8.2 1.6 3.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDJ58840.1 - 0.2 11.6 6.3 0.39 10.7 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain CbiM PF01891.16 CDJ58840.1 - 0.89 9.3 7.0 0.73 9.6 0.1 3.0 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region RskA PF10099.9 CDJ58840.1 - 3 8.1 36.4 0.11 12.8 6.4 4.9 3 1 1 4 4 4 0 Anti-sigma-K factor rskA CemA PF03040.14 CDJ58840.1 - 8.1 6.3 6.0 0.43 10.5 0.3 1.7 2 0 0 2 2 2 0 CemA family Merozoite_SPAM PF07133.11 CDJ58841.1 - 0.002 18.2 40.0 0.0027 17.7 40.0 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CCSAP PF15748.5 CDJ58841.1 - 0.013 15.7 35.3 0.024 14.8 35.3 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CDJ58841.1 - 0.28 9.4 31.8 0.41 8.9 31.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDJ58841.1 - 0.34 9.1 35.8 0.43 8.7 35.8 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CDJ58841.1 - 0.5 8.4 29.1 0.76 7.8 29.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4647 PF15504.6 CDJ58841.1 - 0.91 8.6 26.7 1.3 8.1 26.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Suf PF05843.14 CDJ58841.1 - 0.92 9.4 24.5 1.4 8.8 24.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 CDJ58841.1 - 1.6 9.4 22.3 0.46 11.1 17.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TP53IP5 PF15331.6 CDJ58841.1 - 1.6 8.8 22.3 2.4 8.2 22.3 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Rav1p_C PF12234.8 CDJ58841.1 - 1.7 6.9 12.8 2.1 6.6 12.8 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal Tyrosinase PF00264.20 CDJ58841.1 - 3.3 7.9 8.0 4.5 7.5 8.0 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase NPAT_C PF15712.5 CDJ58841.1 - 3.6 6.1 29.4 4.5 5.8 29.4 1.1 1 0 0 1 1 1 0 NPAT C terminus SR-25 PF10500.9 CDJ58841.1 - 4.2 6.9 54.0 6.7e+03 -3.6 54.0 2.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDRGK PF09756.9 CDJ58841.1 - 4.3 6.9 53.5 6.4 6.3 53.5 1.2 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.9 CDJ58841.1 - 5.6 5.4 31.5 8.2 4.8 31.5 1.2 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 CDJ58841.1 - 5.8 5.8 28.5 7.8 5.4 28.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ58841.1 - 6 6.6 39.2 8.9 6.0 39.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.13 CDJ58841.1 - 6.7 6.3 29.9 9.4 5.8 29.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LSM PF01423.22 CDJ58843.1 - 1.9e-17 62.7 0.0 2.6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDJ58843.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Nop14 PF04147.12 CDJ58844.1 - 0.63 8.2 56.0 0.84 7.8 56.0 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 CDJ58844.1 - 1.3 9.1 24.4 1.9 8.6 24.4 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 CDJ58844.1 - 2.5 7.4 57.7 3.2 7.1 57.7 1.2 1 0 0 1 1 1 0 SDA1 SUIM_assoc PF16619.5 CDJ58845.1 - 0.0012 18.9 0.3 0.0012 18.9 0.3 8.7 3 1 2 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Utp14 PF04615.13 CDJ58845.1 - 0.57 8.7 33.9 0.76 8.3 33.9 1.1 1 0 0 1 1 1 0 Utp14 protein RskA PF10099.9 CDJ58846.1 - 0.00035 20.9 0.1 0.00035 20.9 0.1 4.2 2 1 2 4 4 4 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ58846.1 - 0.0014 17.7 11.7 0.0014 17.7 11.7 3.2 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ58846.1 - 0.0059 16.3 19.8 0.0059 16.3 19.8 3.0 2 1 1 3 3 2 1 Spt20 family SDA1 PF05285.12 CDJ58846.1 - 0.026 14.0 42.3 0.38 10.1 37.8 2.1 2 0 0 2 2 2 0 SDA1 AAA_11 PF13086.6 CDJ58846.1 - 0.12 12.2 18.8 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ASC PF00858.24 CDJ58846.1 - 1.4 7.8 9.0 7.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel AUX_IAA PF02309.16 CDJ58846.1 - 1.9 8.3 15.2 7.4 6.4 0.6 2.3 2 0 0 2 2 2 0 AUX/IAA family Drc1-Sld2 PF11719.8 CDJ58846.1 - 3.3 7.2 37.3 0.37 10.3 25.7 2.2 2 0 0 2 2 2 0 DNA replication and checkpoint protein BUD22 PF09073.10 CDJ58846.1 - 6.5 6.0 41.0 11 5.3 0.1 2.2 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 CDJ58846.1 - 7.6 6.2 44.1 3.8 7.2 1.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM60A PF15396.6 CDJ58846.1 - 8.6 6.3 24.0 7.3 6.5 0.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A FBPase PF00316.20 CDJ58847.1 - 6.5e-67 224.7 0.0 8.4e-67 224.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Med4 PF10018.9 CDJ58850.1 - 0.0014 18.3 1.1 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1604 PF07713.13 CDJ58851.1 - 1.3e-05 24.9 2.2 2e-05 24.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) FSA_C PF10479.9 CDJ58851.1 - 3 5.9 18.1 4.7 5.2 18.1 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 CDJ58851.1 - 3.4 7.8 21.6 10 6.3 21.6 1.8 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Podoplanin PF05808.11 CDJ58852.1 - 0.014 15.5 1.4 0.016 15.3 0.2 1.7 2 0 0 2 2 2 0 Podoplanin Gram_pos_anchor PF00746.21 CDJ58852.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Flp1_like PF16982.5 CDJ58852.1 - 0.091 12.2 0.8 0.17 11.3 0.8 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain SUIM_assoc PF16619.5 CDJ58854.1 - 0.67 10.1 6.0 1.3 9.1 6.1 1.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RNA_pol_Rpb2_1 PF04563.15 CDJ58855.1 - 1.7e-60 204.0 0.0 2.2e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDJ58855.1 - 4.1e-48 163.6 0.0 7.9e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CDJ58855.1 - 1.6e-26 92.2 0.0 3.1e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDJ58856.1 - 3.4e-93 312.4 7.6 3.6e-73 246.6 0.4 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CDJ58856.1 - 9.8e-75 250.3 0.9 1.9e-74 249.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 CDJ58856.1 - 1.7e-67 227.7 0.1 3.3e-67 226.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 CDJ58856.1 - 4.2e-46 157.2 3.6 8.9e-46 156.1 3.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CDJ58856.1 - 4.7e-45 152.9 5.4 1.5e-44 151.3 5.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CDJ58856.1 - 3.7e-43 147.2 0.0 5.1e-42 143.5 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDJ58856.1 - 3.5e-39 133.1 0.3 3.5e-39 133.1 0.3 2.9 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 4 Ribo_biogen_C PF04034.13 CDJ58858.1 - 8.7e-36 122.4 0.0 1.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CDJ58858.1 - 0.00014 21.6 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SUIM_assoc PF16619.5 CDJ58859.1 - 0.11 12.6 3.0 1.1 9.3 0.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Lung_7-TM_R PF06814.13 CDJ58859.1 - 0.12 11.6 2.7 0.24 10.6 2.7 1.4 1 0 0 1 1 1 0 Lung seven transmembrane receptor Blt1_C PF17183.4 CDJ58860.1 - 0.034 13.7 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain DEAD PF00270.29 CDJ58861.1 - 1.6e-50 171.3 0.0 2.8e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58861.1 - 7.3e-34 116.4 0.0 2.3e-33 114.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CDJ58861.1 - 0.0034 16.2 0.1 0.016 14.0 0.0 2.1 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CDJ58861.1 - 0.072 13.4 0.0 2 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain SUIM_assoc PF16619.5 CDJ58861.1 - 1.2 9.2 14.6 0.86 9.7 4.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ58861.1 - 1.4 8.7 3.8 2.4 8.0 3.8 1.3 1 0 0 1 1 1 0 SPX domain AAA PF00004.29 CDJ58862.1 - 3.9e-30 105.0 0.0 8.3e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ58862.1 - 1.6e-13 50.2 0.0 5e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ58862.1 - 1.6e-05 25.2 0.2 0.0052 17.1 0.0 2.6 1 1 2 3 3 3 1 AAA domain Vps4_C PF09336.10 CDJ58862.1 - 1.8e-05 24.7 0.0 7.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CDJ58862.1 - 0.0016 18.8 0.5 0.0056 17.1 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CDJ58862.1 - 0.0036 16.7 0.3 0.0094 15.4 0.3 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDJ58862.1 - 0.004 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ58862.1 - 0.005 16.9 0.1 0.023 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDJ58862.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CDJ58862.1 - 0.028 14.6 0.1 0.062 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ58862.1 - 0.039 14.2 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDJ58862.1 - 0.051 13.2 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDJ58862.1 - 0.067 13.7 0.0 0.22 12.1 0.0 1.9 2 1 0 2 2 1 0 AAA domain Peptidase_M24 PF00557.24 CDJ58862.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 NACHT PF05729.12 CDJ58862.1 - 0.092 12.7 0.3 1.4 8.8 0.0 2.4 2 1 1 3 3 2 0 NACHT domain AFG1_ATPase PF03969.16 CDJ58862.1 - 0.095 11.6 0.2 0.56 9.0 0.2 2.0 1 1 1 2 2 2 0 AFG1-like ATPase AAA_7 PF12775.7 CDJ58862.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CDJ58862.1 - 0.16 12.4 0.0 0.78 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CDJ58862.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ58862.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CDJ58862.1 - 0.2 11.1 0.1 0.42 10.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 CDJ58863.1 - 1.7e-43 148.4 0.0 6.6e-43 146.5 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ58863.1 - 1.6e-30 105.7 0.0 9.4e-30 103.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ58863.1 - 5e-07 29.9 0.1 6.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CDJ58863.1 - 0.0023 17.3 1.0 0.003 16.9 0.0 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain zf-CCHC PF00098.23 CDJ58863.1 - 4.6 7.5 8.6 0.35 11.0 3.6 1.8 2 0 0 2 2 2 0 Zinc knuckle PAN_4 PF14295.6 CDJ58864.1 - 0.077 12.9 0.4 0.17 11.8 0.4 1.6 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.21 CDJ58866.1 - 1.3e-40 139.3 0.0 1.7e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CDJ58866.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 CDJ58867.1 - 2.2e-50 171.2 0.0 2.8e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CDJ58867.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Fringe-like MMR_HSR1 PF01926.23 CDJ58868.1 - 6.2e-10 39.2 0.0 1.4e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ58868.1 - 6.7e-05 22.9 0.0 0.05 13.5 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDJ58868.1 - 0.00026 20.6 0.0 0.93 9.0 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDJ58868.1 - 0.00044 20.4 0.0 0.17 11.9 0.1 2.6 2 0 0 2 2 2 2 Dynamin family Spore_IV_A PF09547.10 CDJ58868.1 - 0.066 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_PrkA PF08298.11 CDJ58868.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain FeoB_N PF02421.18 CDJ58868.1 - 0.18 11.3 1.1 21 4.6 0.0 2.9 4 0 0 4 4 4 0 Ferrous iron transport protein B SMK-1 PF04802.15 CDJ58869.1 - 1.1e-09 38.4 9.9 2.9e-07 30.5 5.3 2.6 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 SR-25 PF10500.9 CDJ58869.1 - 9.1e-05 22.2 22.9 9.1e-05 22.2 22.9 9.4 7 2 3 10 10 10 3 Nuclear RNA-splicing-associated protein Roughex PF06020.11 CDJ58869.1 - 0.00039 19.6 4.5 0.00039 19.6 4.5 7.4 5 2 2 7 7 7 3 Drosophila roughex protein RskA PF10099.9 CDJ58869.1 - 0.0054 17.0 0.8 0.0054 17.0 0.8 10.3 3 2 1 6 6 6 3 Anti-sigma-K factor rskA STOP PF05217.12 CDJ58870.1 - 0.00012 22.3 6.7 0.0011 19.2 1.0 4.6 5 0 0 5 5 5 1 STOP protein PDEase_I PF00233.19 CDJ58871.1 - 1.7e-59 201.4 0.5 1.1e-56 192.2 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase NPL PF17800.1 CDJ58872.1 - 1.1e-09 38.8 0.0 1.1e-09 38.8 0.0 1.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain RskA PF10099.9 CDJ58874.1 - 0.014 15.7 5.7 0.014 15.7 5.7 5.2 3 2 1 4 4 4 0 Anti-sigma-K factor rskA Zip PF02535.22 CDJ58874.1 - 4.3 6.4 32.0 7.3e+02 -0.9 32.0 3.3 1 1 0 1 1 1 0 ZIP Zinc transporter DnaJ PF00226.31 CDJ58875.1 - 2.4e-06 27.6 0.2 5.1e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Hist_deacetyl PF00850.19 CDJ58876.1 - 4.9e-60 203.6 1.8 4.9e-60 203.6 1.8 1.5 2 0 0 2 2 2 1 Histone deacetylase domain DEAD PF00270.29 CDJ58877.1 - 8.4e-35 120.1 8.0 4.6e-33 114.5 8.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Spt20 PF12090.8 CDJ58877.1 - 0.0016 18.1 28.2 0.03 14.0 4.0 3.4 4 0 0 4 4 4 2 Spt20 family Helicase_C PF00271.31 CDJ58877.1 - 0.0068 16.7 1.9 0.068 13.5 0.6 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Suf PF05843.14 CDJ58877.1 - 0.06 13.3 8.1 0.11 12.5 1.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ58877.1 - 0.12 13.4 8.9 3.3 8.7 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) BBP1_N PF15271.6 CDJ58877.1 - 0.52 11.1 4.5 0.96 10.2 0.1 2.6 3 0 0 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein DUF2722 PF10846.8 CDJ58877.1 - 2.9 6.7 28.0 0.046 12.7 1.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 CDJ58877.1 - 4.1 6.1 30.6 0.7 8.7 7.6 3.1 3 0 0 3 3 3 0 Androgen receptor EphA2_TM PF14575.6 CDJ58877.1 - 4.3 8.3 6.3 57 4.7 0.1 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain EPL1 PF10513.9 CDJ58877.1 - 8.7 6.7 9.9 6.1 7.2 0.5 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like SPX PF03105.19 CDJ58878.1 - 0.00026 21.1 9.5 0.00026 21.1 9.5 2.6 2 1 0 2 2 1 1 SPX domain Apt1 PF10351.9 CDJ58878.1 - 0.0037 16.2 14.9 0.0053 15.7 14.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain PAP1 PF08601.10 CDJ58878.1 - 0.021 14.5 16.2 0.045 13.5 16.2 1.6 1 0 0 1 1 1 0 Transcription factor PAP1 NST1 PF13945.6 CDJ58878.1 - 0.037 14.1 8.3 0.057 13.5 8.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Lin-8 PF03353.15 CDJ58878.1 - 0.4 10.2 4.5 0.61 9.6 4.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF913 PF06025.12 CDJ58878.1 - 0.55 9.2 6.8 0.82 8.6 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ58878.1 - 0.88 8.3 8.8 1.3 7.7 8.8 1.1 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 CDJ58878.1 - 0.97 8.7 5.5 1.4 8.2 5.5 1.1 1 0 0 1 1 1 0 FAM76 protein POX PF07526.11 CDJ58878.1 - 1.9 9.1 9.9 3.8 8.1 9.9 1.4 1 0 0 1 1 1 0 Associated with HOX Macoilin PF09726.9 CDJ58878.1 - 2.3 6.7 25.2 4.3 5.8 25.2 1.3 1 0 0 1 1 1 0 Macoilin family Striatin PF08232.12 CDJ58878.1 - 2.9 8.5 6.5 5.2 7.6 6.5 1.3 1 0 0 1 1 1 0 Striatin family Cwf_Cwc_15 PF04889.12 CDJ58878.1 - 4 7.1 8.4 6.5 6.4 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nha1_C PF08619.10 CDJ58879.1 - 0.0027 17.0 9.8 0.0027 17.0 9.8 2.4 2 1 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus SLC12 PF03522.15 CDJ58879.1 - 0.0089 15.1 17.0 0.016 14.2 17.0 1.3 1 0 0 1 1 1 1 Solute carrier family 12 Rxt3 PF08642.10 CDJ58879.1 - 0.027 15.3 6.9 2.3 9.0 2.9 2.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Ribosomal_L30 PF00327.20 CDJ58879.1 - 0.25 11.3 0.3 0.64 9.9 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e RskA PF10099.9 CDJ58879.1 - 0.38 11.0 65.2 0.58 10.4 11.2 4.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Afi1 PF07792.12 CDJ58879.1 - 0.5 10.8 15.0 9.7 6.7 9.9 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FHIPEP PF00771.20 CDJ58879.1 - 1.1 7.7 19.2 0.21 10.0 0.7 2.4 1 1 1 2 2 2 0 FHIPEP family Connexin PF00029.19 CDJ58879.1 - 3.4 7.4 11.1 14 5.3 0.1 2.2 2 0 0 2 2 2 0 Connexin Kin17_mid PF10357.9 CDJ58879.1 - 6.7 6.6 17.0 1.2 9.0 4.5 2.8 3 0 0 3 3 3 0 Domain of Kin17 curved DNA-binding protein GRIP PF01465.20 CDJ58880.1 - 3.9e-11 42.7 0.8 3.9e-11 42.7 0.8 2.7 2 0 0 2 2 2 1 GRIP domain Sec16 PF12932.7 CDJ58880.1 - 0.018 15.6 0.9 0.018 15.6 0.9 6.9 3 2 3 6 6 6 0 Vesicle coat trafficking protein Sec16 mid-region PRIMA1 PF16101.5 CDJ58880.1 - 3.3 7.7 8.8 16 5.6 8.8 2.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Macoilin PF09726.9 CDJ58881.1 - 0.61 8.6 58.5 1.2 7.6 58.5 1.5 1 1 0 1 1 1 0 Macoilin family 2OG-FeII_Oxy_2 PF13532.6 CDJ58881.1 - 1.2 9.2 20.3 0.81 9.8 12.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ribosomal_60s PF00428.19 CDJ58881.1 - 2.5 8.7 21.2 6.7 7.4 2.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Scs3p PF10261.9 CDJ58882.1 - 0.00028 20.5 0.2 0.00028 20.5 0.2 2.6 3 0 0 3 3 3 1 Inositol phospholipid synthesis and fat-storage-inducing TM Tim54 PF11711.8 CDJ58882.1 - 0.0011 17.8 9.8 0.0011 17.8 9.8 3.7 4 0 0 4 4 4 1 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ58882.1 - 0.0013 18.4 17.7 0.0013 18.4 17.7 6.3 5 1 0 6 6 5 1 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 CDJ58882.1 - 0.0018 17.4 7.8 0.0018 17.4 7.8 3.1 3 0 0 3 3 3 1 CLN3 protein Connexin PF00029.19 CDJ58882.1 - 0.0018 18.1 7.3 0.0018 18.1 7.3 3.2 3 0 0 3 3 3 1 Connexin CDC45 PF02724.14 CDJ58882.1 - 0.003 15.9 15.1 0.003 15.9 15.1 3.0 3 0 0 3 3 3 1 CDC45-like protein SpoIIIAH PF12685.7 CDJ58882.1 - 0.009 15.9 15.4 0.009 15.9 15.4 4.2 3 1 0 3 3 2 1 SpoIIIAH-like protein Spt5_N PF11942.8 CDJ58882.1 - 0.0097 16.9 10.2 0.0097 16.9 10.2 4.4 4 0 0 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal DUF4604 PF15377.6 CDJ58882.1 - 0.016 15.6 16.8 0.016 15.6 16.8 3.4 2 1 0 2 2 1 0 Domain of unknown function (DUF4604) DUF2151 PF10221.9 CDJ58882.1 - 0.073 11.7 15.5 0.013 14.1 11.3 1.9 2 0 0 2 2 2 0 Cell cycle and development regulator Sin_N PF04801.13 CDJ58882.1 - 0.082 12.1 45.2 0.0047 16.2 30.6 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region ASC PF00858.24 CDJ58882.1 - 0.18 10.7 6.3 0.37 9.7 6.3 1.5 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel HCO3_cotransp PF00955.21 CDJ58882.1 - 1.4 7.7 7.2 3.1 6.5 7.2 1.5 1 0 0 1 1 1 0 HCO3- transporter family OATP PF03137.20 CDJ58882.1 - 1.4 7.1 13.5 0.027 12.8 2.1 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SID-1_RNA_chan PF13965.6 CDJ58882.1 - 2 6.7 8.8 4.7 5.5 8.8 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nucleoside_tran PF01733.18 CDJ58882.1 - 3.2 7.1 6.3 7.9 5.8 6.3 1.6 1 0 0 1 1 1 0 Nucleoside transporter SpoIIP PF07454.11 CDJ58882.1 - 5.2 6.4 36.1 0.022 14.2 18.3 3.2 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CDJ58882.1 - 5.5 5.0 27.8 0.46 8.6 19.9 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PIP5K PF01504.18 CDJ58882.1 - 7.1 5.8 22.3 3.7 6.7 15.4 3.1 1 1 1 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF3_subunit PF08597.10 CDJ58883.1 - 0.0038 17.2 10.5 0.004 17.1 10.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit rve PF00665.26 CDJ58884.1 - 1.3e-07 31.8 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.25 CDJ58886.1 - 8.8e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NPR3 PF03666.13 CDJ58887.1 - 0.068 12.0 11.7 0.12 11.2 11.7 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 CDJ58887.1 - 0.81 8.5 14.5 1.4 7.7 14.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CDJ58887.1 - 1.3 8.2 4.0 2.1 7.5 4.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 CDJ58887.1 - 3.1 6.2 6.4 4 5.8 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 CDJ58887.1 - 8.5 3.3 9.5 11 2.9 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2151 PF10221.9 CDJ58887.1 - 9.3 4.7 12.7 16 4.0 12.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator OATP PF03137.20 CDJ58888.1 - 0.0017 16.7 2.7 0.0017 16.7 2.7 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pim PF16765.5 CDJ58889.1 - 0.042 14.0 0.2 0.13 12.5 0.2 1.8 1 0 0 1 1 1 0 Pesticin immunity protein SAC3_GANP PF03399.16 CDJ58890.1 - 1.5e-07 31.2 4.1 0.02 14.3 0.0 3.0 2 1 1 3 3 3 3 SAC3/GANP family TAF4 PF05236.14 CDJ58890.1 - 0.00025 20.9 0.1 0.00031 20.6 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TraT PF05818.12 CDJ58890.1 - 1.7 8.2 7.2 2.5 7.7 7.2 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein RSRP PF17069.5 CDJ58891.1 - 0.0069 16.0 2.0 0.0069 16.0 2.0 4.3 3 1 1 4 4 2 1 Arginine/Serine-Rich protein 1 Ribosomal_60s PF00428.19 CDJ58891.1 - 0.022 15.3 9.5 0.022 15.3 9.5 13.5 8 3 5 13 13 8 0 60s Acidic ribosomal protein SR-25 PF10500.9 CDJ58891.1 - 0.12 12.0 62.4 0.027 14.1 13.4 3.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 CDJ58891.1 - 0.14 12.2 29.0 1.3 9.1 3.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CDJ58891.1 - 1.5 7.0 19.6 0.17 10.1 10.5 2.4 2 0 0 2 2 2 0 CDC45-like protein FAM60A PF15396.6 CDJ58891.1 - 1.6 8.7 22.4 1.4 8.9 9.7 3.4 3 0 0 3 3 3 0 Protein Family FAM60A MMR1 PF08505.10 CDJ58891.1 - 2.8 8.2 35.9 0.08 13.2 19.1 3.1 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein SID-1_RNA_chan PF13965.6 CDJ58891.1 - 5.7 5.2 5.1 14 4.0 5.1 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Apt1 PF10351.9 CDJ58891.1 - 5.7 5.7 34.0 0.94 8.3 13.6 3.1 3 0 0 3 3 3 0 Golgi-body localisation protein domain PAT1 PF09770.9 CDJ58891.1 - 6.3 4.9 41.1 0.24 9.6 23.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CDJ58891.1 - 7.5 5.4 17.0 14 4.5 17.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Merozoite_SPAM PF07133.11 CDJ58891.1 - 8.4 6.3 18.0 2.3 8.2 11.1 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Y2_Tnp PF04986.13 CDJ58891.1 - 9.5 6.2 8.3 20 5.1 8.3 1.5 1 0 0 1 1 1 0 Putative transposase Sin_N PF04801.13 CDJ58892.1 - 1.4e-05 24.5 13.8 1.4e-05 24.5 13.8 6.8 2 2 3 5 5 5 1 Sin-like protein conserved region Spt20 PF12090.8 CDJ58893.1 - 0.15 11.6 10.5 0.2 11.2 10.5 1.3 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ58893.1 - 0.44 9.5 20.4 0.64 8.9 20.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4192 PF13830.6 CDJ58893.1 - 5.3 7.0 25.9 0.58 10.2 20.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF3446 PF11928.8 CDJ58893.1 - 8.6 6.7 17.3 0.12 12.7 3.8 2.7 2 1 0 2 2 2 0 Early growth response N-terminal domain PDEase_I PF00233.19 CDJ58894.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DUF572 PF04502.13 CDJ58894.1 - 0.089 12.4 2.4 0.1 12.2 1.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) MASE2 PF05230.11 CDJ58894.1 - 0.15 12.1 4.2 0.37 10.9 3.3 2.2 1 1 0 1 1 1 0 MASE2 domain DUF1635 PF07795.11 CDJ58894.1 - 0.19 11.6 8.4 6.9 6.5 3.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) DUF966 PF06136.13 CDJ58894.1 - 1.6 8.4 9.3 4.1 7.0 9.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Sel1 PF08238.12 CDJ58895.1 - 2.1e-05 25.0 0.1 6.3e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Sel1 repeat Spt20 PF12090.8 CDJ58895.1 - 0.00032 20.4 22.6 0.00032 20.4 22.6 7.8 6 2 0 6 6 6 1 Spt20 family zf-RING_2 PF13639.6 CDJ58896.1 - 9.1e-12 45.1 6.0 9.1e-12 45.1 6.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ58896.1 - 1.2e-08 34.7 6.3 3.4e-08 33.2 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ58896.1 - 3.7e-08 32.9 5.8 8.7e-08 31.8 5.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CDJ58896.1 - 4.3e-07 29.8 2.3 4.3e-07 29.8 2.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDJ58896.1 - 4.8e-06 26.8 6.8 3.5e-05 24.0 6.8 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDJ58896.1 - 9.8e-06 25.4 4.4 9.8e-06 25.4 4.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ58896.1 - 0.00013 21.7 5.2 0.00013 21.7 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ58896.1 - 0.00017 21.5 1.4 0.00017 21.5 1.4 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDJ58896.1 - 0.092 12.8 1.8 0.34 11.0 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CDJ58896.1 - 0.19 12.1 1.3 0.6 10.5 1.3 2.0 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 CDJ58896.1 - 0.49 10.1 7.1 0.63 9.8 5.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_4 PF14447.6 CDJ58896.1 - 1.4 8.9 13.8 0.16 11.9 8.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 LPG_synthase_TM PF03706.13 CDJ58898.1 - 0.0089 15.6 2.6 0.67 9.4 0.0 2.1 2 0 0 2 2 2 2 Lysylphosphatidylglycerol synthase TM region TFIIA PF03153.13 CDJ58898.1 - 0.011 15.8 28.4 0.016 15.2 28.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDJ58898.1 - 0.49 8.6 21.2 0.63 8.3 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.15 CDJ58898.1 - 3 6.7 4.9 8.1 5.2 4.3 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) FAM222A PF15258.6 CDJ58898.1 - 3.2 6.8 24.2 4.3 6.3 24.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Peptidase_U57 PF05582.12 CDJ58898.1 - 3.4 6.9 9.3 5.2 6.2 9.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 MAJIN PF15077.6 CDJ58898.1 - 3.9 7.2 10.9 6.2 6.5 10.9 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein MRP-L46 PF11788.8 CDJ58898.1 - 4.6 8.0 22.3 2 9.2 16.1 2.2 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 DUF823 PF05689.11 CDJ58898.1 - 8.1 6.2 10.8 14 5.4 10.8 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) TERB2 PF15101.6 CDJ58898.1 - 8.1 6.4 19.2 15 5.6 19.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Kelch_5 PF13854.6 CDJ58899.1 - 8.3e-11 41.6 0.1 1.8e-06 27.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CDJ58899.1 - 8.2e-07 28.9 0.1 0.0023 17.9 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ58899.1 - 1.7e-05 24.9 14.5 0.23 11.8 0.0 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ58899.1 - 0.00012 22.2 0.1 0.065 13.6 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CDJ58899.1 - 0.041 13.9 1.3 23 5.1 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Peptidase_A22B PF04258.13 CDJ58900.1 - 1.2e-64 218.6 9.0 1.6e-64 218.1 9.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CDJ58900.1 - 0.007 15.9 14.4 0.33 10.4 14.4 2.5 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Secretin_N_2 PF07655.13 CDJ58902.1 - 0.0054 17.3 11.6 0.0054 17.3 11.6 6.6 5 1 1 6 6 6 3 Secretin N-terminal domain SAE2 PF08573.10 CDJ58902.1 - 0.0076 17.4 5.4 0.0076 17.4 5.4 7.5 3 2 2 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Myosin_head PF00063.21 CDJ58903.1 - 1.1e-50 172.6 1.0 1.1e-50 172.6 1.0 4.2 5 1 0 5 5 5 2 Myosin head (motor domain) Sporozoite_P67 PF05642.11 CDJ58903.1 - 0.00017 19.9 2.1 0.00017 19.9 2.1 5.0 4 1 0 4 4 4 2 Sporozoite P67 surface antigen RskA PF10099.9 CDJ58903.1 - 0.00064 20.1 1.6 0.00064 20.1 1.6 6.9 4 2 2 6 6 6 3 Anti-sigma-K factor rskA PIP5K PF01504.18 CDJ58903.1 - 3.1 6.9 22.4 0.91 8.7 0.1 4.1 4 1 0 4 4 4 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2722 PF10846.8 CDJ58904.1 - 0.0012 17.9 17.8 0.0012 17.9 17.8 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) K_channel_TID PF07941.11 CDJ58904.1 - 0.0043 17.5 13.4 0.0043 17.5 13.4 17.7 5 3 6 11 11 11 1 Potassium channel Kv1.4 tandem inactivation domain Atg14 PF10186.9 CDJ58904.1 - 7.3 5.6 42.4 1 8.4 11.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 CDJ58905.1 - 3.9e-41 141.2 1.1 3.9e-38 131.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58905.1 - 2.4e-20 72.9 3.4 9.2e-15 54.6 0.1 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ58905.1 - 7.6e-07 28.2 4.5 7.6e-07 28.2 4.5 2.4 2 1 0 2 2 2 1 Fungal protein kinase DUF2722 PF10846.8 CDJ58905.1 - 3.1e-05 23.1 5.2 3.1e-05 23.1 5.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Kdo PF06293.14 CDJ58905.1 - 0.00015 21.2 4.9 0.00015 21.2 4.9 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Spt20 PF12090.8 CDJ58905.1 - 0.0098 15.5 22.9 0.0098 15.5 22.9 2.5 3 0 0 3 3 2 2 Spt20 family DUF3464 PF11947.8 CDJ58905.1 - 0.011 15.5 8.3 0.38 10.5 2.6 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 CDJ58905.1 - 0.012 15.4 4.4 0.012 15.4 4.4 3.0 3 1 0 3 3 1 0 Transmembrane protein 51 APH PF01636.23 CDJ58905.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 CDJ58905.1 - 0.053 13.5 42.8 0.07 13.1 16.4 2.4 3 0 0 3 3 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ58905.1 - 0.066 13.9 31.6 0.17 12.5 6.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ58905.1 - 0.13 12.0 3.6 0.81 9.4 0.2 2.2 2 0 0 2 2 2 0 Connexin EPL1 PF10513.9 CDJ58905.1 - 0.13 12.6 12.7 0.088 13.2 1.0 2.9 3 0 0 3 3 3 0 Enhancer of polycomb-like AIF_C PF14721.6 CDJ58905.1 - 0.18 12.2 9.6 0.84 10.0 0.4 3.0 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Roughex PF06020.11 CDJ58905.1 - 0.22 10.6 14.6 1.3 8.1 0.6 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Lgl_C PF08596.10 CDJ58905.1 - 0.26 10.0 6.0 0.95 8.1 0.1 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal Apc15p PF05841.11 CDJ58905.1 - 0.29 11.9 21.2 1.6 9.5 6.0 3.4 3 0 0 3 3 3 0 Apc15p protein DUF4770 PF15994.5 CDJ58905.1 - 0.34 11.1 11.9 0.8 9.9 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) OATP PF03137.20 CDJ58905.1 - 0.39 8.9 1.9 3.3 5.9 0.2 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Thg1C PF14413.6 CDJ58905.1 - 0.43 10.7 9.0 0.5 10.5 1.7 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain Pet20 PF08692.10 CDJ58905.1 - 0.47 11.2 2.9 5.2 7.8 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 TERB2 PF15101.6 CDJ58905.1 - 0.59 10.2 19.1 0.054 13.5 4.3 2.8 3 0 0 3 3 3 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 CDJ58905.1 - 0.62 9.0 17.2 0.38 9.7 6.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) U3_snoRNA_assoc PF08297.11 CDJ58905.1 - 0.81 10.4 6.3 5.6 7.7 1.7 2.8 2 0 0 2 2 2 0 U3 snoRNA associated FAM60A PF15396.6 CDJ58905.1 - 0.95 9.4 13.2 1.3 9.0 1.3 2.9 3 0 0 3 3 3 0 Protein Family FAM60A RNA_pol_Rbc25 PF08292.12 CDJ58905.1 - 0.99 9.6 6.8 0.55 10.5 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 DUF4834 PF16118.5 CDJ58905.1 - 1 10.4 21.4 0.5 11.4 6.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) MCU PF04678.13 CDJ58905.1 - 1 9.4 9.0 5.5 7.1 1.5 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF3504 PF12012.8 CDJ58905.1 - 1.2 9.0 9.0 1.6 8.6 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Tsg PF04668.12 CDJ58905.1 - 2 9.1 6.7 3.6 8.3 1.9 2.3 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region V_ATPase_I PF01496.19 CDJ58905.1 - 2.5 5.9 9.6 0.44 8.4 2.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 CDJ58905.1 - 2.5 7.5 5.5 1.6 8.2 0.3 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 SpoIIP PF07454.11 CDJ58905.1 - 2.8 7.3 12.9 0.8 9.1 4.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF1764 PF08576.10 CDJ58905.1 - 2.9 8.8 11.2 1.8 9.5 2.4 2.7 3 0 0 3 3 2 0 Eukaryotic protein of unknown function (DUF1764) FHIPEP PF00771.20 CDJ58905.1 - 3.2 6.1 7.9 1.8 7.0 0.9 2.1 2 0 0 2 2 2 0 FHIPEP family Activator_LAG-3 PF11498.8 CDJ58905.1 - 3.7 6.4 46.7 0.072 12.0 5.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MMM1 PF10296.9 CDJ58905.1 - 3.7 6.5 8.9 6.3 5.7 1.2 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Hydin_ADK PF17213.3 CDJ58905.1 - 4.8 7.4 24.0 0.57 10.4 7.4 2.9 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain CLN3 PF02487.17 CDJ58905.1 - 5.1 6.0 7.4 0.99 8.4 0.5 2.1 2 0 0 2 2 2 0 CLN3 protein EphA2_TM PF14575.6 CDJ58905.1 - 6.4 7.7 9.2 1.4 9.9 1.6 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OmpH PF03938.14 CDJ58905.1 - 7.1 7.0 35.2 2.5 8.4 9.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FAM150 PF15129.6 CDJ58905.1 - 7.7 6.7 11.8 20 5.3 6.4 2.6 2 0 0 2 2 2 0 FAM150 family Suf PF05843.14 CDJ58905.1 - 8.4 6.3 22.2 1.1 9.2 6.1 2.5 3 0 0 3 3 2 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ58905.1 - 8.8 4.9 43.9 0.27 9.9 18.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal EIIBC-GUT_N PF03612.14 CDJ58905.1 - 9.6 5.9 11.8 3.1 7.5 3.6 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3449 PF11931.8 CDJ58906.1 - 1.6e-10 41.1 0.8 2.1e-10 40.7 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) FAM176 PF14851.6 CDJ58906.1 - 0.026 14.2 0.6 0.031 14.0 0.6 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CDJ58906.1 - 0.29 9.2 6.0 0.33 9.0 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CDJ58906.1 - 0.36 10.1 5.5 0.36 10.1 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein S-antigen PF05756.11 CDJ58906.1 - 0.36 11.2 3.0 0.53 10.7 3.0 1.3 1 0 0 1 1 1 0 S-antigen protein Med17 PF10156.9 CDJ58906.1 - 0.77 8.4 6.9 0.79 8.4 6.9 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex SUIM_assoc PF16619.5 CDJ58908.1 - 0.011 15.7 60.8 0.27 11.3 9.1 4.8 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 FSA_C PF10479.9 CDJ58908.1 - 8.6 4.4 10.0 15 3.5 10.0 1.5 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CGI-121 PF08617.10 CDJ58909.1 - 3.9e-14 53.1 7.0 9.9e-13 48.5 0.3 2.9 3 0 0 3 3 3 2 Kinase binding protein CGI-121 TFIIA PF03153.13 CDJ58909.1 - 1.6e-05 25.1 35.6 0.003 17.6 12.4 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 CDJ58909.1 - 0.0036 16.6 1.2 0.0036 16.6 1.2 2.3 2 0 0 2 2 2 1 Sin-like protein conserved region Spt20 PF12090.8 CDJ58909.1 - 0.0052 16.4 23.2 0.0052 16.4 23.2 3.0 3 0 0 3 3 3 2 Spt20 family DUF3402 PF11882.8 CDJ58909.1 - 0.0081 15.3 3.4 0.013 14.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) RskA PF10099.9 CDJ58909.1 - 0.01 16.2 15.8 0.38 11.0 0.7 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA SLC12 PF03522.15 CDJ58909.1 - 0.026 13.6 7.4 0.032 13.3 2.1 2.2 2 0 0 2 2 2 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 CDJ58909.1 - 0.027 14.9 2.1 0.027 14.9 2.1 3.1 4 0 0 4 4 4 0 RNA polymerase III RPC4 eIF-3_zeta PF05091.12 CDJ58909.1 - 0.23 10.4 12.3 0.087 11.8 3.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAXIP1_C PF15364.6 CDJ58909.1 - 0.32 11.3 11.8 1.8 8.9 6.5 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein CCSAP PF15748.5 CDJ58909.1 - 0.87 9.7 23.0 0.88 9.7 12.0 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CLN3 PF02487.17 CDJ58909.1 - 1.1 8.3 5.8 0.63 9.0 1.9 2.3 2 0 0 2 2 2 0 CLN3 protein RCR PF12273.8 CDJ58909.1 - 1.1 9.9 11.9 2.6 8.7 1.5 2.7 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Med15 PF09606.10 CDJ58909.1 - 1.2 7.7 35.1 1.4 7.5 14.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Afi1 PF07792.12 CDJ58909.1 - 1.6 9.3 11.0 3 8.3 5.9 2.7 3 0 0 3 3 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Suf PF05843.14 CDJ58909.1 - 3.5 7.5 13.8 3.4 7.6 4.6 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4366 PF14283.6 CDJ58909.1 - 5.1 7.1 12.3 0.16 12.0 1.9 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4366) Chorein_N PF12624.7 CDJ58909.1 - 5.8 7.1 13.2 9.2 6.4 0.8 2.6 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 RR_TM4-6 PF06459.12 CDJ58909.1 - 6.1 6.6 12.6 5.2 6.8 6.5 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2681 PF10883.8 CDJ58909.1 - 7.4 7.1 20.8 10 6.6 6.5 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2681) DUF4692 PF15763.5 CDJ58909.1 - 10 6.6 26.2 5 7.6 7.1 3.6 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) PrsW-protease PF13367.6 CDJ58911.1 - 1.7e-10 40.7 17.7 9e-09 35.1 4.9 4.3 5 0 0 5 5 5 2 PrsW family intramembrane metalloprotease DUF1980 PF09323.10 CDJ58911.1 - 0.42 10.5 7.7 11 5.8 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TFIIA PF03153.13 CDJ58911.1 - 0.81 9.6 52.6 0.92 9.4 23.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RCR PF12273.8 CDJ58911.1 - 4.1 8.1 22.1 0.47 11.1 7.5 3.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red GAGA_bind PF06217.12 CDJ58911.1 - 5.2 7.3 12.6 0.42 10.8 2.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family CDC45 PF02724.14 CDJ58912.1 - 0.00041 18.8 3.7 0.00046 18.6 3.7 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 CDJ58912.1 - 0.0067 14.7 10.5 0.0077 14.5 10.5 1.0 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 CDJ58912.1 - 0.016 15.3 17.5 0.022 14.9 17.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Metallophos PF00149.28 CDJ58913.1 - 1.1e-28 101.1 0.0 1.5e-28 100.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_2 PF07646.15 CDJ58913.1 - 7.8e-08 32.0 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 CDJ58913.1 - 5.1e-07 29.2 0.2 1.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CDJ58913.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 CDJ58913.1 - 0.00029 20.8 0.0 0.00076 19.4 0.0 1.7 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ58913.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CDJ58913.1 - 0.12 12.7 0.1 0.97 9.8 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain TFIIA PF03153.13 CDJ58913.1 - 4 7.3 22.6 0.11 12.5 16.5 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ING PF12998.7 CDJ58916.1 - 4.3e-08 33.7 1.4 4.3e-08 33.7 1.4 3.6 2 2 1 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding CcdA PF07362.12 CDJ58916.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.7 5 1 0 5 5 5 0 Post-segregation antitoxin CcdA DUF5479 PF17575.2 CDJ58916.1 - 0.96 10.0 4.8 2 9.0 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Dicer_dimer PF03368.14 CDJ58917.1 - 0.0052 16.9 0.9 0.0052 16.9 0.9 2.7 2 1 0 2 2 2 1 Dicer dimerisation domain CNDH2_C PF16858.5 CDJ58917.1 - 0.018 14.9 25.6 0.14 12.0 10.2 3.3 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AAA_11 PF13086.6 CDJ58917.1 - 1.8 8.3 25.6 0.66 9.7 9.8 3.6 3 0 0 3 3 3 0 AAA domain HC2 PF07382.11 CDJ58918.1 - 7.6e-09 35.9 65.1 8.2e-06 26.0 19.5 3.8 1 1 4 5 5 5 5 Histone H1-like nucleoprotein HC2 NblA PF04485.12 CDJ58918.1 - 5e-05 23.6 38.3 13 6.3 0.1 12.7 4 4 7 11 11 11 5 Phycobilisome degradation protein nblA SATase_N PF06426.14 CDJ58918.1 - 0.078 13.4 19.1 0.19 12.1 0.9 4.9 1 1 5 6 6 6 0 Serine acetyltransferase, N-terminal GRP PF07172.11 CDJ58919.1 - 0.012 16.3 0.0 0.012 16.3 0.0 2.4 3 1 0 3 3 3 0 Glycine rich protein family DUF572 PF04502.13 CDJ58919.1 - 8.6 5.9 14.3 2 8.0 11.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) ICE2 PF08426.10 CDJ58920.1 - 2.2 7.3 5.2 2.3 7.2 0.8 3.3 3 0 0 3 3 3 0 ICE2 PDEase_I PF00233.19 CDJ58921.1 - 9.2e-66 222.0 0.7 1.1e-65 221.7 0.7 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CDJ58921.1 - 0.15 12.3 0.6 0.51 10.6 0.4 2.1 1 1 1 2 2 2 0 HD domain BSP_II PF05432.11 CDJ58922.1 - 0.079 12.6 9.5 0.14 11.9 9.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Thioredoxin_15 PF18403.1 CDJ58922.1 - 0.68 9.8 9.3 0.82 9.6 8.4 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DcuA_DcuB PF03605.14 CDJ58922.1 - 1.1 8.1 3.2 1.8 7.4 3.2 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter CARMIL_C PF16000.5 CDJ58922.1 - 2.1 7.9 22.6 0.1 12.2 17.0 1.5 2 0 0 2 2 2 0 CARMIL C-terminus PAPS_reduct PF01507.19 CDJ58923.1 - 1.1e-11 45.1 0.1 2e-11 44.2 0.1 1.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TMEM208_SND2 PF05620.11 CDJ58923.1 - 7.3 6.3 10.8 0.26 11.1 0.5 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 RskA PF10099.9 CDJ58923.1 - 7.7 6.8 22.5 18 5.6 16.9 2.9 2 1 0 2 2 2 0 Anti-sigma-K factor rskA CAC1F_C PF16885.5 CDJ58924.1 - 2 8.0 30.2 2.4 7.7 30.2 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SLIDE PF09111.10 CDJ58925.1 - 0.0058 16.6 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 SLIDE AAA PF00004.29 CDJ58927.1 - 1.7e-12 47.9 0.0 2.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ58927.1 - 2.2e-06 27.5 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CDJ58927.1 - 0.00081 19.2 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CDJ58927.1 - 0.00098 19.4 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ58927.1 - 0.002 18.5 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDJ58927.1 - 0.0038 17.2 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CDJ58927.1 - 0.0044 16.6 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ58927.1 - 0.0053 16.2 0.1 0.0083 15.5 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CDJ58927.1 - 0.0083 15.4 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CDJ58927.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ58927.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDJ58927.1 - 0.019 14.4 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 CDJ58927.1 - 0.024 15.2 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDJ58927.1 - 0.035 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDJ58927.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CDJ58927.1 - 0.044 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CDJ58927.1 - 0.058 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CDJ58927.1 - 0.064 12.4 0.0 0.093 11.9 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 CDJ58927.1 - 0.07 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 CDJ58927.1 - 0.072 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ58927.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 CDJ58927.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 CDJ58927.1 - 0.2 11.3 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 CDJ58927.1 - 0.25 10.4 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4200 PF13863.6 CDJ58929.1 - 0.013 15.9 6.4 0.013 15.9 6.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CpG_bind_C PF12269.8 CDJ58929.1 - 1.9 8.2 29.8 0.047 13.5 2.8 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Sin_N PF04801.13 CDJ58929.1 - 2.3 7.4 37.1 2.9 7.0 37.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Ndc1_Nup PF09531.10 CDJ58929.1 - 5.8 5.5 15.2 6.5 5.3 15.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cellulose_synt PF03552.14 CDJ58929.1 - 6.2 5.2 7.0 6.4 5.1 7.0 1.2 1 0 0 1 1 1 0 Cellulose synthase zf-Tim10_DDP PF02953.15 CDJ58930.1 - 4.8e-10 38.9 5.6 7.1e-10 38.4 5.1 1.7 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Pam16 PF03656.13 CDJ58930.1 - 1.2 9.1 5.4 3.1 7.8 4.4 1.9 1 1 0 1 1 1 0 Pam16 ADH_zinc_N PF00107.26 CDJ58931.1 - 1e-24 87.0 0.1 1.6e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDJ58931.1 - 8.4e-07 28.8 0.8 8.4e-07 28.8 0.8 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDJ58931.1 - 1.9e-05 24.3 0.0 5.6e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDJ58931.1 - 0.0011 18.3 0.4 0.0017 17.7 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CDJ58931.1 - 0.0016 18.0 0.2 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CDJ58931.1 - 0.26 10.6 0.8 0.65 9.3 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L5 PF00281.19 CDJ58932.1 - 1.3e-21 76.7 0.2 2.3e-21 75.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 CDJ58932.1 - 3.5e-16 59.2 0.0 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus SUIM_assoc PF16619.5 CDJ58933.1 - 0.0013 18.8 2.6 0.0013 18.8 2.6 3.6 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ58933.1 - 0.0045 16.6 4.8 0.0045 16.6 4.8 3.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FAM60A PF15396.6 CDJ58933.1 - 1.4 8.8 13.8 15 5.5 0.6 3.3 3 0 0 3 3 3 0 Protein Family FAM60A ATP-synt PF00231.19 CDJ58934.1 - 0.0072 16.1 0.0 0.0075 16.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase DUF2723 PF11028.8 CDJ58934.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF1002 PF06207.11 CDJ58935.1 - 0.037 13.5 1.7 0.061 12.9 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) DSPc PF00782.20 CDJ58936.1 - 1e-16 61.0 0.0 7.1e-15 55.0 0.0 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Mo25 PF08569.11 CDJ58936.1 - 0.1 11.9 0.6 0.16 11.3 0.6 1.2 1 0 0 1 1 1 0 Mo25-like DUF5536 PF17688.1 CDJ58936.1 - 5.4 6.9 14.4 0.036 13.9 3.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5536) Pkinase PF00069.25 CDJ58937.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Proteasome PF00227.26 CDJ58938.1 - 9.6e-22 77.4 0.0 1.2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ58938.1 - 5.7e-14 51.5 0.0 8.3e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TFIIA PF03153.13 CDJ58939.1 - 0.0014 18.7 10.0 0.0022 18.1 10.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ58939.1 - 0.24 11.0 18.9 1.2 8.8 10.3 2.1 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Utp14 PF04615.13 CDJ58939.1 - 2.6 6.5 10.4 3.3 6.2 10.4 1.1 1 0 0 1 1 1 0 Utp14 protein Pyrid_oxidase_2 PF13883.6 CDJ58939.1 - 4.9 7.1 7.4 9 6.2 7.4 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Secretin_N_2 PF07655.13 CDJ58939.1 - 6.2 7.4 36.0 9.5 6.8 2.3 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain 14-3-3 PF00244.20 CDJ58941.1 - 1.6e-94 315.5 4.5 2e-94 315.3 4.5 1.1 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 CDJ58941.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MKT1_N PF12247.8 CDJ58941.1 - 0.075 13.4 0.9 0.19 12.1 0.1 2.2 2 1 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_C PF04679.15 CDJ58942.1 - 1.8e-14 54.1 0.9 5.4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.21 CDJ58942.1 - 0.00019 21.1 0.1 0.00019 21.1 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain RskA PF10099.9 CDJ58942.1 - 0.043 14.1 8.9 0.087 13.1 8.9 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA BSP_II PF05432.11 CDJ58942.1 - 0.14 11.9 20.9 0.17 11.6 20.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PA26 PF04636.13 CDJ58942.1 - 0.25 10.2 9.2 0.26 10.2 9.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CRISPR_Cse2 PF09485.10 CDJ58942.1 - 0.57 10.7 6.7 0.91 10.0 6.7 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PPP4R2 PF09184.11 CDJ58942.1 - 0.76 9.3 20.1 0.88 9.1 20.1 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 CDJ58942.1 - 0.84 8.9 12.2 1.4 8.2 12.2 1.5 1 0 0 1 1 1 0 NOA36 protein CSG2 PF16965.5 CDJ58942.1 - 2.8 6.8 3.6 3.1 6.7 3.6 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4629 PF15442.6 CDJ58942.1 - 3.6 7.8 18.2 13 6.0 17.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) R_equi_Vir PF05526.11 CDJ58942.1 - 3.7 7.4 6.1 6.2 6.6 6.1 1.5 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SID-1_RNA_chan PF13965.6 CDJ58942.1 - 4 5.7 4.2 4 5.7 4.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 CDJ58942.1 - 4.8 5.9 13.2 5.2 5.7 13.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Velvet PF11754.8 CDJ58942.1 - 5.2 6.9 11.1 6.4 6.6 11.1 1.2 1 0 0 1 1 1 0 Velvet factor E1_dh PF00676.20 CDJ58943.1 - 1.2e-08 34.2 0.1 1.4e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Mak10 PF04112.13 CDJ58945.1 - 0.67 9.4 4.0 0.99 8.9 0.6 2.7 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Methyltr_RsmB-F PF01189.17 CDJ58946.1 - 1.2e-16 60.9 2.0 3.6e-07 30.0 0.0 4.0 3 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ58946.1 - 0.0032 17.6 0.5 0.32 11.1 0.1 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDJ58946.1 - 0.0065 16.3 5.8 0.058 13.2 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ58946.1 - 0.0076 16.9 0.2 0.29 11.9 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ58946.1 - 0.037 14.7 0.0 8.1 7.2 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Utp14 PF04615.13 CDJ58946.1 - 0.39 9.2 21.6 0.51 8.8 21.6 1.1 1 0 0 1 1 1 0 Utp14 protein PIEZO PF15917.5 CDJ58946.1 - 0.4 10.1 11.9 0.72 9.3 11.9 1.3 1 0 0 1 1 1 0 Piezo Methyltransf_23 PF13489.6 CDJ58946.1 - 3.1 7.6 11.7 3.5 7.4 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Zip PF02535.22 CDJ58946.1 - 5.4 6.1 6.7 9.8 5.3 6.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 CDJ58946.1 - 9.8 5.0 13.5 18 4.2 13.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Transketolase_C PF02780.20 CDJ58948.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Transketolase, C-terminal domain IMP2_N PF18590.1 CDJ58950.1 - 8.4e-26 90.4 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) N-terminal domain IMP2_C PF18591.1 CDJ58950.1 - 0.00052 19.8 0.5 0.00097 19.0 0.5 1.4 1 0 0 1 1 1 1 Immune Mapped Protein 2 (IMP2) C-terminal domain Biotin_lipoyl PF00364.22 CDJ58951.1 - 5.5e-19 67.8 1.6 9.7e-19 67.0 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 CDJ58951.1 - 2.5e-05 25.8 0.5 9.7e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S36, mitochondrial Biotin_lipoyl_2 PF13533.6 CDJ58951.1 - 0.00083 19.1 1.7 0.2 11.5 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CDJ58951.1 - 0.073 13.8 1.5 5 7.9 0.3 2.4 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 CDJ58951.1 - 0.32 10.9 1.0 0.55 10.1 0.6 1.6 2 0 0 2 2 2 0 Glycine cleavage H-protein DSHCT PF08148.12 CDJ58952.1 - 2.5e-21 76.0 0.0 2.7e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain Sporozoite_P67 PF05642.11 CDJ58953.1 - 0.0037 15.4 11.4 0.0043 15.2 11.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen rRNA_proc-arch PF13234.6 CDJ58953.1 - 0.033 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain DUF515 PF04415.12 CDJ58953.1 - 0.37 9.1 14.5 0.57 8.5 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SSP160 PF06933.11 CDJ58953.1 - 4.9 5.2 19.7 6.6 4.8 19.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Spt20 PF12090.8 CDJ58954.1 - 0.0023 17.6 8.5 0.0023 17.6 8.5 3.6 4 0 0 4 4 4 1 Spt20 family PBP1_TM PF14812.6 CDJ58954.1 - 0.023 15.1 1.1 0.023 15.1 1.1 7.9 8 0 0 8 8 8 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RskA PF10099.9 CDJ58957.1 - 0.017 15.4 0.2 0.017 15.4 0.2 4.4 1 1 2 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ58957.1 - 0.021 14.8 76.0 0.0082 16.2 30.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glt_symporter PF03616.14 CDJ58957.1 - 1.1 7.9 5.6 0.48 9.0 0.2 2.3 2 0 0 2 2 2 0 Sodium/glutamate symporter FPN1 PF06963.12 CDJ58957.1 - 3 6.3 8.2 1.7 7.1 0.8 2.3 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Ureide_permease PF07168.11 CDJ58957.1 - 7 5.3 9.2 1.5 7.5 2.8 2.2 2 0 0 2 2 2 0 Ureide permease SUIM_assoc PF16619.5 CDJ58958.1 - 0.014 15.5 14.7 0.014 15.5 14.7 7.6 6 2 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CDJ58958.1 - 0.11 12.3 0.2 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_alpha_N PF12254.8 CDJ58959.1 - 4.8e-16 58.6 4.0 4.8e-16 58.6 4.0 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal SR-25 PF10500.9 CDJ58959.1 - 0.013 15.1 12.4 0.013 15.1 12.4 4.9 4 1 2 6 6 6 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ58959.1 - 7.5 6.4 45.3 0.0089 16.1 19.3 2.7 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ58961.1 - 0.0024 18.2 0.0 0.0024 18.2 0.0 15.9 2 1 9 11 11 11 2 Anti-sigma-K factor rskA PDEase_I PF00233.19 CDJ58962.1 - 0.015 15.1 0.3 0.025 14.3 0.3 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Pyr_redox_2 PF07992.14 CDJ58963.1 - 1.5e-11 44.1 1.1 2.4e-08 33.6 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDJ58963.1 - 9.7e-07 29.0 0.5 0.00016 21.9 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDJ58963.1 - 0.00073 20.1 1.5 0.0015 19.0 1.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CDJ58963.1 - 0.0045 16.4 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDJ58963.1 - 0.19 11.3 0.4 0.33 10.5 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Exo_endo_phos PF03372.23 CDJ58964.1 - 6.1e-05 22.6 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SseC PF04888.12 CDJ58967.1 - 0.0038 16.9 12.7 0.0038 16.9 12.7 4.7 4 1 0 4 4 2 1 Secretion system effector C (SseC) like family DUF1387 PF07139.11 CDJ58967.1 - 0.19 11.4 11.6 0.26 11.0 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PA26 PF04636.13 CDJ58967.1 - 0.23 10.4 3.9 0.33 9.8 3.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCM_bind PF09739.9 CDJ58967.1 - 0.4 9.1 9.4 0.68 8.3 9.4 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Endostatin PF06482.11 CDJ58967.1 - 0.45 9.9 8.5 0.39 10.1 4.1 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SURF6 PF04935.12 CDJ58967.1 - 0.55 10.0 22.4 0.092 12.5 12.1 2.4 2 1 0 2 2 2 0 Surfeit locus protein 6 Suf PF05843.14 CDJ58967.1 - 0.56 10.1 15.9 1.7 8.6 7.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SART-1 PF03343.13 CDJ58967.1 - 0.69 8.4 17.1 0.96 7.9 17.1 1.2 1 0 0 1 1 1 0 SART-1 family Peptidase_S64 PF08192.11 CDJ58967.1 - 1 7.7 7.9 2.2 6.7 7.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 SpoIIP PF07454.11 CDJ58967.1 - 1 8.7 13.7 0.69 9.3 10.5 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CDJ58967.1 - 1.2 7.4 10.7 2.1 6.6 10.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 CDJ58967.1 - 1.3 8.5 20.6 0.74 9.3 15.0 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 CDJ58967.1 - 1.4 8.3 16.9 1.3 8.4 15.9 1.4 1 1 0 1 1 1 0 SDA1 TCP PF03634.13 CDJ58967.1 - 2.3 8.8 16.0 0.73 10.4 11.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF1980 PF09323.10 CDJ58967.1 - 2.3 8.1 7.5 1.3 8.9 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Membralin PF09746.9 CDJ58967.1 - 2.9 6.9 3.6 4.3 6.3 3.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF908 PF06012.12 CDJ58967.1 - 3.8 6.8 15.0 1.5 8.2 6.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) eIF-3_zeta PF05091.12 CDJ58967.1 - 5.8 5.8 14.9 0.23 10.4 8.3 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 CDJ58967.1 - 6.6 5.4 6.3 10 4.8 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Activator_LAG-3 PF11498.8 CDJ58967.1 - 8.3 5.3 41.5 0.014 14.4 23.9 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Connexin PF00029.19 CDJ58968.1 - 0.029 14.1 4.8 0.029 14.1 4.8 1.0 1 0 0 1 1 1 0 Connexin PIP5K PF01504.18 CDJ58968.1 - 0.11 11.8 3.4 0.12 11.6 3.4 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF5523 PF17661.1 CDJ58968.1 - 0.45 10.2 19.7 0.48 10.1 19.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Tim54 PF11711.8 CDJ58968.1 - 0.45 9.3 11.2 0.48 9.1 11.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 CDJ58968.1 - 0.47 9.7 7.1 0.51 9.6 7.1 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Dynactin_p62 PF05502.13 CDJ58968.1 - 0.5 9.1 4.7 0.48 9.1 4.7 1.0 1 0 0 1 1 1 0 Dynactin p62 family CPSF100_C PF13299.6 CDJ58968.1 - 0.53 10.4 6.8 0.67 10.1 6.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 CDJ58968.1 - 0.63 9.2 12.7 0.68 9.1 12.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 CDJ58968.1 - 0.83 8.8 5.3 0.88 8.7 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 CDJ58968.1 - 0.86 9.9 12.7 0.99 9.7 12.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 CDJ58968.1 - 1 7.5 25.1 1.1 7.4 25.1 1.0 1 0 0 1 1 1 0 Nop14-like family Serinc PF03348.15 CDJ58968.1 - 1 8.2 3.5 0.87 8.4 3.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Afi1 PF07792.12 CDJ58968.1 - 1.1 9.8 10.5 1.2 9.6 10.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CLN3 PF02487.17 CDJ58968.1 - 1.1 8.2 2.6 1.1 8.3 2.6 1.0 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ58968.1 - 1.2 8.9 14.3 1.3 8.8 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ58968.1 - 1.6 7.4 8.3 1.8 7.3 8.3 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ58968.1 - 1.6 8.8 3.7 1.7 8.8 3.7 1.1 1 0 0 1 1 1 0 DDHD domain ORC_WH_C PF18137.1 CDJ58968.1 - 1.7 8.7 11.0 2 8.5 11.0 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal CobT PF06213.12 CDJ58968.1 - 2.2 7.6 24.8 2.7 7.3 24.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CDJ58968.1 - 2.4 7.5 24.8 2.6 7.4 24.8 1.0 1 0 0 1 1 1 0 SDA1 Eapp_C PF10238.9 CDJ58968.1 - 2.8 8.0 8.6 3.7 7.6 8.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3306 PF11748.8 CDJ58968.1 - 3.3 8.6 10.9 3.8 8.4 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Drc1-Sld2 PF11719.8 CDJ58968.1 - 3.9 6.9 17.2 4.1 6.8 17.2 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein CTU2 PF10288.9 CDJ58968.1 - 4.2 7.6 6.9 4.8 7.5 6.9 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 NPR3 PF03666.13 CDJ58968.1 - 4.4 6.0 9.4 4.6 5.9 9.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.13 CDJ58968.1 - 4.4 6.2 25.7 5.2 5.9 25.7 1.0 1 0 0 1 1 1 0 Paf1 DDRGK PF09756.9 CDJ58968.1 - 4.8 6.7 25.9 5.7 6.5 25.9 1.1 1 0 0 1 1 1 0 DDRGK domain RNA_pol_Rpc4 PF05132.14 CDJ58968.1 - 4.9 7.6 9.0 5.8 7.3 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 CDJ58968.1 - 5.4 5.9 7.4 5.8 5.8 7.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RAB3GAP2_C PF14656.6 CDJ58968.1 - 5.6 5.1 6.5 5.5 5.1 6.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus TFIIF_alpha PF05793.12 CDJ58968.1 - 5.7 5.4 28.2 6.3 5.3 28.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_delta_4 PF04081.13 CDJ58968.1 - 6 7.2 14.8 7.4 6.9 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 DARPP-32 PF05395.12 CDJ58968.1 - 6.1 7.1 18.5 8 6.7 18.5 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 YqfQ PF14181.6 CDJ58968.1 - 6.2 7.0 10.5 6.7 6.9 10.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein ATP-synt_E PF05680.12 CDJ58968.1 - 6.5 7.2 11.0 8.7 6.8 11.0 1.3 1 0 0 1 1 1 0 ATP synthase E chain BUD22 PF09073.10 CDJ58968.1 - 6.9 5.9 22.2 7.7 5.7 22.2 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 CDJ58968.1 - 6.9 6.4 18.5 9.6 5.9 18.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop53 PF07767.11 CDJ58968.1 - 7.8 5.8 25.1 8.5 5.7 25.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 CDJ58968.1 - 7.8 4.5 30.0 8.9 4.3 30.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 CDJ58968.1 - 8.1 4.4 6.4 8.4 4.4 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gcd10p PF04189.13 CDJ58968.1 - 8.2 5.4 9.8 9.6 5.2 9.8 1.0 1 0 0 1 1 1 0 Gcd10p family CSRNP_N PF16019.5 CDJ58968.1 - 9.3 6.1 9.0 11 5.8 9.0 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RskA PF10099.9 CDJ58969.1 - 0.0015 18.9 0.8 0.0015 18.9 0.8 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA RRM_7 PF16367.5 CDJ58969.1 - 0.15 12.2 1.2 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Ribosomal_60s PF00428.19 CDJ58969.1 - 3.7 8.2 11.0 10 6.8 11.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2258 PF10015.9 CDJ58970.1 - 0.1 12.7 0.1 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) HSP20 PF00011.21 CDJ58971.1 - 3.3e-12 46.5 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ58971.1 - 4.4e-06 26.2 0.0 1.5e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA TFIIA PF03153.13 CDJ58972.1 - 1.3e-07 32.0 26.9 2e-07 31.4 26.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tfb2 PF03849.14 CDJ58972.1 - 4e-07 29.3 5.1 0.0055 15.7 5.4 2.2 2 0 0 2 2 2 2 Transcription factor Tfb2 Med15 PF09606.10 CDJ58972.1 - 0.44 9.2 32.0 0.75 8.4 32.0 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LRR_4 PF12799.7 CDJ58973.1 - 3.8e-10 39.9 22.4 0.0055 17.1 0.4 4.6 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ58973.1 - 1e-08 34.8 21.5 4e-05 23.3 5.9 3.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 CDJ58973.1 - 3e-05 24.0 10.0 0.048 14.2 0.2 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 CDJ58973.1 - 0.0014 18.5 14.2 3.3 8.0 0.1 6.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 CDJ58973.1 - 0.11 12.0 4.6 0.2 11.2 0.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeat RAP1 PF07218.11 CDJ58976.1 - 0.092 11.0 4.2 0.12 10.7 4.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MAGE_N PF12440.8 CDJ58976.1 - 1.5 9.6 22.3 2.2 9.0 5.3 3.2 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Spt20 PF12090.8 CDJ58976.1 - 5.8 6.5 9.5 5.8 6.5 6.8 2.0 2 0 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.13 CDJ58977.1 - 0.19 10.7 36.0 0.59 9.1 19.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor AATase PF07247.12 CDJ58981.1 - 0.04 12.5 0.0 0.3 9.6 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase HEAT PF02985.22 CDJ58982.1 - 0.29 11.5 1.3 5.7 7.5 0.0 4.0 2 0 0 2 2 2 0 HEAT repeat JmjC PF02373.22 CDJ58983.1 - 4.4e-34 117.3 1.0 4.4e-34 117.3 1.0 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.17 CDJ58983.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 jmjN domain Arf PF00025.21 CDJ58984.1 - 8.6e-37 126.3 0.2 3.2e-35 121.1 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDJ58984.1 - 9.3e-09 35.5 0.5 4.8e-07 30.0 0.5 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDJ58984.1 - 4.6e-07 29.3 0.2 0.00029 20.1 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDJ58984.1 - 2.2e-06 27.2 0.1 0.00079 18.8 0.0 2.1 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 CDJ58984.1 - 0.0045 16.6 0.2 0.018 14.6 0.1 1.8 1 1 1 2 2 2 1 Ras family SRPRB PF09439.10 CDJ58984.1 - 0.006 16.0 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDJ58984.1 - 0.0098 16.0 0.1 0.96 9.5 0.1 2.2 1 1 1 2 2 2 2 50S ribosome-binding GTPase TFIIA PF03153.13 CDJ58985.1 - 0.0013 18.8 41.1 0.011 15.8 21.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CDJ58985.1 - 0.042 11.0 13.5 0.0025 15.1 4.8 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 CDJ58985.1 - 2.2 7.7 15.5 0.94 8.9 5.5 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin LIN52 PF10044.9 CDJ58985.1 - 2.3 9.0 10.6 0.059 14.1 2.7 2.4 2 1 0 2 2 2 0 Retinal tissue protein eIF-5a PF01287.20 CDJ58986.1 - 7.2e-26 90.1 0.2 1.1e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDJ58986.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain MAP PF03642.13 CDJ58986.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 MAP domain RskA PF10099.9 CDJ58989.1 - 0.0019 18.5 7.9 0.0019 18.5 7.9 7.0 2 2 4 6 6 6 1 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ58989.1 - 0.0058 15.6 6.3 0.0058 15.6 6.3 6.0 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) Pkinase PF00069.25 CDJ58990.1 - 9.3e-31 107.1 0.1 1.2e-15 57.6 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ58990.1 - 5.1e-15 55.5 0.0 6.9e-08 32.1 0.4 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDJ58990.1 - 1.2e-06 28.1 1.2 0.0062 15.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ58990.1 - 2e-05 24.6 0.5 2e-05 24.6 0.5 2.5 2 1 1 3 3 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 CDJ58990.1 - 0.00021 21.0 1.9 0.00021 21.0 1.9 1.8 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Macoilin PF09726.9 CDJ58990.1 - 0.0022 16.7 13.0 0.0031 16.1 13.0 1.1 1 0 0 1 1 1 1 Macoilin family TFIIA PF03153.13 CDJ58990.1 - 0.0025 17.9 28.6 0.0037 17.3 28.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ58990.1 - 0.0037 17.5 8.5 0.0057 16.9 8.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ58990.1 - 0.0046 16.6 30.5 0.0087 15.7 30.5 1.5 1 0 0 1 1 1 1 Spt20 family CCDC53 PF10152.9 CDJ58990.1 - 0.018 15.4 5.7 0.034 14.5 5.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CSG2 PF16965.5 CDJ58990.1 - 0.15 11.0 1.4 0.22 10.4 1.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator SpoIIP PF07454.11 CDJ58990.1 - 0.15 11.5 10.0 0.23 10.9 10.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ58990.1 - 0.16 11.8 10.2 0.24 11.2 10.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ58990.1 - 0.26 9.5 22.2 0.35 9.1 22.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ58990.1 - 0.27 10.8 18.9 0.41 10.2 18.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ58990.1 - 0.28 11.2 6.2 0.48 10.4 6.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.11 CDJ58990.1 - 0.35 10.2 3.3 0.48 9.8 3.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CPSF100_C PF13299.6 CDJ58990.1 - 0.36 11.0 7.5 0.63 10.2 7.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CDJ58990.1 - 0.36 9.2 3.2 0.48 8.8 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMU163 PF17119.5 CDJ58990.1 - 0.37 9.9 3.1 0.67 9.1 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PNISR PF15996.5 CDJ58990.1 - 0.46 10.7 18.5 0.78 10.0 18.5 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Peptidase_S49_N PF08496.10 CDJ58990.1 - 0.47 10.5 8.3 0.85 9.7 8.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EPL1 PF10513.9 CDJ58990.1 - 0.64 10.4 11.3 1.1 9.6 11.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like GREB1 PF15782.5 CDJ58990.1 - 0.76 6.8 17.1 1 6.4 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM51 PF15345.6 CDJ58990.1 - 1.3 8.8 13.1 2.3 8.0 13.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Coilin_N PF15862.5 CDJ58990.1 - 1.3 8.8 12.8 3 7.6 12.8 1.5 1 0 0 1 1 1 0 Coilin N-terminus eIF-3_zeta PF05091.12 CDJ58990.1 - 1.5 7.7 20.6 2.2 7.2 20.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDJ58990.1 - 2.1 8.3 13.0 3.5 7.5 13.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CobT PF06213.12 CDJ58990.1 - 2.4 7.5 19.5 4.2 6.7 19.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2828 PF11443.8 CDJ58990.1 - 2.4 6.1 12.3 3.5 5.6 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ58990.1 - 2.7 6.7 17.0 3.9 6.1 17.0 1.2 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 CDJ58990.1 - 2.9 6.1 5.9 4.3 5.5 5.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1980 PF09323.10 CDJ58990.1 - 2.9 7.8 6.4 4.8 7.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FAM176 PF14851.6 CDJ58990.1 - 3.4 7.3 7.7 6.4 6.4 7.7 1.4 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 CDJ58990.1 - 3.7 7.2 11.2 3.4 7.4 9.7 1.6 2 0 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus tRNA_synt_1c_R2 PF04557.15 CDJ58990.1 - 5.6 8.0 13.1 11 7.0 13.1 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Band_3_cyto PF07565.13 CDJ58990.1 - 5.6 6.7 12.2 11 5.8 12.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Connexin PF00029.19 CDJ58990.1 - 6.2 6.5 11.8 9.9 5.8 11.8 1.2 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 CDJ58990.1 - 6.4 5.7 15.7 9.1 5.2 15.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 UPF0560 PF10577.9 CDJ58990.1 - 7.1 5.0 22.2 11 4.3 22.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MAS20 PF02064.15 CDJ58990.1 - 9.4 6.3 20.8 23 5.1 20.8 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Methyltransf_12 PF08242.12 CDJ58990.1 - 9.4 7.1 6.5 1.7 9.5 2.0 2.2 2 1 0 2 2 1 0 Methyltransferase domain DUF2722 PF10846.8 CDJ58991.1 - 7.6e-07 28.4 1.4 7.6e-07 28.4 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ58991.1 - 0.022 14.8 5.3 0.82 9.7 8.1 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Hep_59 PF07052.11 CDJ58991.1 - 0.049 14.4 4.3 26 5.6 5.7 2.1 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Med15 PF09606.10 CDJ58991.1 - 0.067 11.9 13.7 0.081 11.6 13.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PH_4 PF15404.6 CDJ58991.1 - 0.22 11.3 3.9 0.31 10.8 3.9 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Presenilin PF01080.17 CDJ58991.1 - 0.26 10.0 1.8 0.33 9.7 1.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CDJ58991.1 - 0.31 12.0 6.0 0.44 11.5 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) GET2 PF08690.10 CDJ58991.1 - 0.33 10.6 6.5 0.42 10.2 6.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ58991.1 - 0.34 10.8 17.9 0.44 10.5 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ58991.1 - 3.1 8.4 13.0 2.7 8.6 11.2 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ58991.1 - 3.4 7.2 27.9 4.9 6.7 27.9 1.2 1 0 0 1 1 1 0 Spt20 family RNA_pol_Rbc25 PF08292.12 CDJ58991.1 - 4 7.7 8.3 7.3 6.8 7.5 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 MnhB PF04039.13 CDJ58992.1 - 0.016 15.5 1.5 0.03 14.6 1.2 1.6 1 1 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter SSP160 PF06933.11 CDJ58993.1 - 0.07 11.3 9.4 0.081 11.1 9.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hamartin PF04388.12 CDJ58993.1 - 0.082 11.6 22.5 0.096 11.3 22.5 1.1 1 0 0 1 1 1 0 Hamartin protein BSP_II PF05432.11 CDJ58993.1 - 0.84 9.3 21.3 1.4 8.5 21.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 CDJ58993.1 - 1.6 8.0 37.6 0.14 11.4 18.8 2.0 2 0 0 2 2 2 0 BUD22 SRP-alpha_N PF04086.13 CDJ58993.1 - 1.9 8.4 30.5 2.6 7.9 30.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_pp85 PF04637.12 CDJ58993.1 - 2.2 6.6 9.5 3.6 5.9 9.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) adh_short PF00106.25 CDJ58993.1 - 3.3 7.1 8.1 0.2 11.1 2.9 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DUF572 PF04502.13 CDJ58993.1 - 3.4 7.2 30.5 4.6 6.8 30.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3807 PF12720.7 CDJ58993.1 - 6.8 6.9 37.2 8.4 6.6 13.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) NifU_N PF01592.16 CDJ58994.1 - 9e-48 161.7 0.1 1.1e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Peptidase_C12 PF01088.21 CDJ58995.1 - 4.3e-07 29.9 0.4 1.6e-06 28.1 0.3 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Spt20 PF12090.8 CDJ58995.1 - 0.045 13.4 20.2 0.071 12.7 7.6 2.1 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 CDJ58995.1 - 7.4 5.6 19.7 2.6 7.1 9.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal La PF05383.17 CDJ58996.1 - 1.7e-11 44.0 0.4 2.1e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 La domain RskA PF10099.9 CDJ58996.1 - 0.00069 19.9 1.0 0.00069 19.9 1.0 8.7 1 1 5 6 6 6 2 Anti-sigma-K factor rskA SpoIIP PF07454.11 CDJ58996.1 - 0.0029 17.1 1.5 0.0029 17.1 1.5 7.0 5 3 0 5 5 5 1 Stage II sporulation protein P (SpoIIP) TMEM223 PF14640.6 CDJ58996.1 - 8.2 6.6 0.0 8.2 6.6 0.0 4.6 5 0 0 5 5 5 0 Transmembrane protein 223 AP2 PF00847.20 CDJ58998.1 - 4.1e-07 30.1 0.7 0.042 14.1 0.0 3.4 2 0 0 2 2 2 2 AP2 domain LRR_4 PF12799.7 CDJ59001.1 - 2.1e-13 50.2 9.8 0.00018 21.8 0.3 4.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ59001.1 - 8.5e-07 28.7 13.1 0.0059 16.3 1.7 4.4 1 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CDJ59001.1 - 2.1e-05 24.1 0.2 8.1e-05 22.2 0.1 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDJ59001.1 - 2.8e-05 23.8 12.3 0.84 9.9 0.1 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CDJ59001.1 - 6.3e-05 23.0 13.5 3.5 8.6 0.1 6.4 5 1 1 6 6 6 2 Leucine Rich Repeat SIS PF01380.22 CDJ59002.1 - 5.6e-35 120.0 0.5 1.1e-18 67.4 0.0 2.9 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDJ59002.1 - 3.9e-20 72.4 0.0 8.1e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDJ59002.1 - 5.1e-16 58.7 0.0 9.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDJ59002.1 - 2.8e-05 23.2 0.1 5.7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II C2 PF00168.30 CDJ59003.1 - 0.027 14.8 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 C2 domain DUF4398 PF14346.6 CDJ59003.1 - 1.7 9.4 5.0 27 5.5 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Ubie_methyltran PF01209.18 CDJ59004.1 - 1.6e-69 233.8 0.0 1.4e-44 152.2 0.0 3.1 3 0 0 3 3 3 3 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDJ59004.1 - 3.9e-12 46.7 0.0 8.2e-06 26.4 0.0 3.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ59004.1 - 1.1e-10 42.0 0.0 2.6e-09 37.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ59004.1 - 1.2e-07 31.7 0.0 0.009 15.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ59004.1 - 3.6e-05 24.4 0.0 0.00013 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ59004.1 - 5.2e-05 23.1 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDJ59004.1 - 0.04 13.8 0.0 0.97 9.2 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase zf-CCCH_4 PF18044.1 CDJ59006.1 - 0.00049 19.8 3.1 0.00049 19.8 3.1 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDJ59006.1 - 0.00081 19.2 3.6 0.002 18.0 3.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ59006.1 - 0.0096 15.9 4.2 0.021 14.9 4.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CDJ59006.1 - 0.032 14.9 1.0 0.032 14.9 1.0 4.2 5 0 0 5 5 5 0 Torus domain RskA PF10099.9 CDJ59007.1 - 0.0032 17.8 6.1 0.0032 17.8 6.1 12.8 5 3 5 10 10 10 1 Anti-sigma-K factor rskA DUF2052 PF09747.9 CDJ59008.1 - 0.11 12.6 35.4 0.14 12.3 35.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 CDJ59008.1 - 0.24 9.6 31.1 0.25 9.5 31.1 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 CDJ59008.1 - 1.3 9.4 40.8 1.5 9.2 40.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 CDJ59008.1 - 1.8 6.7 34.7 1.9 6.7 34.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.18 CDJ59008.1 - 2.8 6.2 14.2 3.6 5.9 14.2 1.0 1 0 0 1 1 1 0 Membrane transport protein RR_TM4-6 PF06459.12 CDJ59008.1 - 2.9 7.7 39.4 3.4 7.4 39.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4569 PF15133.6 CDJ59008.1 - 3.8 7.1 30.3 4.3 7.0 30.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Rtf2 PF04641.12 CDJ59008.1 - 4 6.7 31.6 4.7 6.5 31.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4045 PF13254.6 CDJ59008.1 - 5.5 6.5 28.8 6.1 6.4 28.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) COX6A PF02046.15 CDJ59008.1 - 5.9 7.4 14.4 8.4 6.9 14.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF4647 PF15504.6 CDJ59008.1 - 6.2 5.8 34.2 7.7 5.5 34.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Sporozoite_P67 PF05642.11 CDJ59008.1 - 8.5 4.3 27.3 10 4.1 27.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.7 CDJ59008.1 - 9.5 4.2 33.1 10 4.1 33.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pro_isomerase PF00160.21 CDJ59010.1 - 6.1e-50 169.6 0.0 8.6e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDJ59010.1 - 0.14 13.0 0.0 0.4 11.6 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat PQQ_2 PF13360.6 CDJ59012.1 - 0.006 16.2 0.0 0.006 16.2 0.0 1.0 1 0 0 1 1 1 1 PQQ-like domain RAB3GAP2_N PF14655.6 CDJ59012.1 - 0.061 12.6 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.8 CDJ59013.1 - 6.1e-05 22.2 8.0 9.1e-05 21.6 8.0 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ59013.1 - 0.0014 18.7 6.5 0.0018 18.4 6.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MTP18 PF10558.9 CDJ59013.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) MAP65_ASE1 PF03999.12 CDJ59013.1 - 0.0098 14.6 2.1 0.0098 14.6 2.1 1.3 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) DUF3429 PF11911.8 CDJ59013.1 - 0.0098 16.2 1.0 0.018 15.3 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) PepSY_TM PF03929.16 CDJ59013.1 - 0.072 12.7 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM region GREB1 PF15782.5 CDJ59013.1 - 0.086 10.0 6.2 0.1 9.7 6.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 CDJ59013.1 - 0.14 11.8 13.6 0.22 11.1 13.6 1.2 1 0 0 1 1 1 0 Spt20 family TAF4 PF05236.14 CDJ59013.1 - 0.32 10.7 4.6 0.32 10.7 1.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF5421 PF17458.2 CDJ59013.1 - 6.1 6.1 8.6 10 5.4 8.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF4718 PF15842.5 CDJ59013.1 - 6.9 6.4 13.6 0.025 14.4 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Roughex PF06020.11 CDJ59013.1 - 9.6 5.2 6.3 15 4.5 6.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 CDJ59013.1 - 10 5.0 20.3 0.068 12.1 12.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Afi1 PF07792.12 CDJ59014.1 - 5e-05 23.8 42.7 0.0017 18.8 0.0 5.9 4 1 1 5 5 5 2 Docking domain of Afi1 for Arf3 in vesicle trafficking RskA PF10099.9 CDJ59014.1 - 0.0044 17.3 1.2 0.0044 17.3 1.2 9.3 3 3 2 8 8 8 2 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ59015.1 - 3.1e-05 23.7 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5401 PF17380.2 CDJ59015.1 - 0.043 11.9 1.3 0.051 11.7 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF179 PF02622.15 CDJ59016.1 - 4.8e-09 36.4 0.0 2.9e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 Glycolytic PF00274.19 CDJ59017.1 - 8.8e-163 541.0 0.0 9.9e-163 540.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RRM_1 PF00076.22 CDJ59018.1 - 1.3e-73 242.7 0.1 5.5e-20 71.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDJ59018.1 - 2e-27 95.2 1.9 1.1e-26 92.8 1.7 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 CDJ59018.1 - 0.00012 22.2 0.1 0.8 9.9 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDJ59018.1 - 0.003 17.5 0.0 7.5 6.6 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif FAM199X PF15814.5 CDJ59018.1 - 0.039 13.0 7.1 0.073 12.1 7.1 1.4 1 0 0 1 1 1 0 Protein family FAM199X TerD PF02342.18 CDJ59019.1 - 7.7e-06 25.5 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 TerD domain DUF2730 PF10805.8 CDJ59019.1 - 0.008 16.3 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.12 CDJ59019.1 - 0.031 14.3 1.0 0.06 13.4 1.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 CDJ59019.1 - 0.039 14.3 1.6 0.21 12.0 0.1 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nsp1_C PF05064.13 CDJ59019.1 - 0.068 13.0 0.3 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region ZapB PF06005.12 CDJ59019.1 - 0.084 13.3 2.0 0.16 12.4 2.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF4164 PF13747.6 CDJ59019.1 - 0.094 13.0 2.1 0.13 12.5 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 CDJ59019.1 - 0.24 11.8 0.8 1.2 9.6 0.4 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 CDJ59019.1 - 0.73 10.3 3.3 0.72 10.3 1.8 1.7 2 0 0 2 2 2 0 Snapin/Pallidin DEAD PF00270.29 CDJ59021.1 - 1.7e-32 112.6 0.0 2.9e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ59021.1 - 3e-27 95.2 0.1 3.8e-26 91.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ59021.1 - 0.066 13.2 0.0 0.48 10.4 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Proteasome PF00227.26 CDJ59022.1 - 3.2e-59 199.6 0.0 4.4e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDJ59022.1 - 1.6e-09 37.2 0.0 1.6e-09 37.2 0.0 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature SR-25 PF10500.9 CDJ59024.1 - 0.014 15.0 9.6 0.014 15.0 9.6 3.9 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ59024.1 - 0.46 10.3 35.8 1.3 8.8 4.8 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 CDJ59024.1 - 0.48 10.1 35.5 0.38 10.4 5.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5523) DUF3807 PF12720.7 CDJ59024.1 - 0.49 10.6 42.2 0.21 11.8 8.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) DAG_kinase_N PF14513.6 CDJ59024.1 - 2.8 8.1 31.4 0.94 9.7 5.1 3.2 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus SID-1_RNA_chan PF13965.6 CDJ59024.1 - 5.3 5.3 18.0 0.42 9.0 3.9 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 RskA PF10099.9 CDJ59025.1 - 0.00021 21.7 29.7 0.00082 19.7 8.1 5.2 2 2 2 4 4 4 3 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 CDJ59025.1 - 0.011 16.3 6.8 0.011 16.3 6.8 6.6 4 2 2 6 6 6 0 60s Acidic ribosomal protein CD20 PF04103.15 CDJ59026.1 - 0.00051 20.1 9.6 0.029 14.5 0.0 4.3 4 0 0 4 4 4 2 CD20-like family DUF3038 PF11237.8 CDJ59027.1 - 0.0027 17.8 1.6 0.0027 17.8 1.6 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3038) SAGA-Tad1 PF12767.7 CDJ59027.1 - 0.61 9.8 9.1 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3408 PF11888.8 CDJ59027.1 - 6.2 7.0 15.6 0.56 10.3 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) Apt1 PF10351.9 CDJ59028.1 - 0.12 11.3 17.4 0.13 11.1 17.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CDJ59028.1 - 0.8 8.8 8.9 0.88 8.6 8.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Mcm10 PF09332.11 CDJ59028.1 - 0.89 8.9 7.3 1.2 8.5 7.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor PPP4R2 PF09184.11 CDJ59028.1 - 1 8.9 12.2 1.1 8.8 12.2 1.1 1 0 0 1 1 1 0 PPP4R2 Ipi1_N PF12333.8 CDJ59028.1 - 1.2 9.7 8.6 0.92 10.1 0.4 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation SPX PF03105.19 CDJ59028.1 - 2.1 8.1 18.7 2.6 7.9 18.7 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.7 CDJ59028.1 - 4.4 5.3 10.1 4.8 5.2 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CytochromB561_N PF09786.9 CDJ59028.1 - 7 5.5 17.6 9.2 5.1 17.6 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal SMC_hinge PF06470.13 CDJ59030.1 - 1.3 9.4 3.8 0.97 9.8 0.4 2.5 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain LYTB PF02401.18 CDJ59031.1 - 2.3e-70 236.9 1.9 3.2e-70 236.4 1.9 1.2 1 0 0 1 1 1 1 LytB protein DNA_primase_S PF01896.19 CDJ59032.1 - 1.3e-33 116.5 0.0 2.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit SR-25 PF10500.9 CDJ59032.1 - 2.9 7.5 7.8 4.1 7.0 7.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3385 PF11865.8 CDJ59034.1 - 0.04 13.8 0.1 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) ELMO_CED12 PF04727.13 CDJ59036.1 - 1.8e-11 44.5 0.0 2.7e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 ELMO/CED-12 family His_Phos_2 PF00328.22 CDJ59037.1 - 7.9e-15 55.1 1.6 2.6e-06 27.1 1.4 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PGC7_Stella PF15549.6 CDJ59037.1 - 0.7 9.9 17.0 0.033 14.2 8.2 3.1 3 0 0 3 3 3 0 PGC7/Stella/Dppa3 domain IMUP PF15761.5 CDJ59039.1 - 0.0021 18.8 6.0 0.0021 18.8 6.0 7.7 8 1 0 8 8 8 2 Immortalisation up-regulated protein GDP_Man_Dehyd PF16363.5 CDJ59040.1 - 1.1e-108 363.6 0.0 6.6e-106 354.5 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDJ59040.1 - 3.1e-50 170.9 0.0 1.2e-49 169.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDJ59040.1 - 2.8e-05 23.4 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ59040.1 - 0.0075 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2371 PF10177.9 CDJ59041.1 - 0.23 11.6 0.1 0.71 10.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) PvlArgDC PF01862.16 CDJ59042.1 - 0.0051 16.6 1.8 0.0086 15.9 1.7 1.3 1 1 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Med15 PF09606.10 CDJ59042.1 - 0.0053 15.5 26.7 0.0057 15.4 26.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal MR_MLE_N PF02746.16 CDJ59042.1 - 0.0059 16.8 1.8 0.009 16.2 1.8 1.2 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UCH_1 PF13423.6 CDJ59042.1 - 0.016 14.8 1.7 0.016 14.8 1.7 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TFIIA PF03153.13 CDJ59042.1 - 0.029 14.4 19.8 0.034 14.2 19.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ59042.1 - 0.13 11.8 8.5 0.16 11.5 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDJ59042.1 - 0.31 10.3 10.3 0.38 10.1 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 CDJ59042.1 - 0.55 9.1 32.7 0.72 8.8 32.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.6 CDJ59042.1 - 0.8 7.5 22.8 0.86 7.4 22.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ZYG-11_interact PF05884.12 CDJ59042.1 - 1.4 8.3 5.9 1.7 8.0 5.9 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 PMI_typeI PF01238.21 CDJ59042.1 - 1.4 8.0 8.4 0.52 9.4 5.6 1.6 2 0 0 2 2 2 0 Phosphomannose isomerase type I TERB2 PF15101.6 CDJ59042.1 - 2.3 8.2 7.8 3.2 7.7 7.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GTP_EFTU_D3 PF03143.17 CDJ59043.1 - 2.2e-21 76.2 0.0 3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ59043.1 - 0.00022 21.5 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DNA_pol_phi PF04931.13 CDJ59044.1 - 0.0036 15.5 36.0 0.015 13.4 15.4 2.0 2 0 0 2 2 2 2 DNA polymerase phi DUF4820 PF16091.5 CDJ59044.1 - 0.015 14.6 22.0 0.088 12.2 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 CDJ59044.1 - 0.019 14.4 34.4 0.028 13.9 34.4 1.2 1 0 0 1 1 1 0 SDA1 OKR_DC_1_C PF03711.15 CDJ59044.1 - 0.046 14.0 0.2 0.046 14.0 0.2 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain Afi1 PF07792.12 CDJ59044.1 - 0.049 14.1 27.7 0.041 14.4 7.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 CDJ59044.1 - 0.057 13.1 27.4 0.5 10.0 9.1 2.5 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.11 CDJ59044.1 - 0.08 12.5 33.0 0.031 13.9 10.1 2.2 2 0 0 2 2 2 0 PPP4R2 MCD PF05292.11 CDJ59044.1 - 0.41 10.2 4.7 1.8 8.1 0.3 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Androgen_recep PF02166.16 CDJ59044.1 - 0.98 8.2 27.1 0.24 10.2 10.8 2.1 2 0 0 2 2 2 0 Androgen receptor NOA36 PF06524.12 CDJ59044.1 - 1.1 8.5 36.4 0.52 9.6 16.1 2.1 2 0 0 2 2 2 0 NOA36 protein Astro_capsid_p PF12226.8 CDJ59044.1 - 1.3 8.1 24.7 0.37 9.9 5.2 2.1 2 0 0 2 2 2 0 Turkey astrovirus capsid protein TLP-20 PF06088.11 CDJ59044.1 - 2.3 8.1 21.3 0.87 9.5 5.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4834 PF16118.5 CDJ59044.1 - 3.3 8.7 31.2 5.5 8.0 12.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SLAIN PF15301.6 CDJ59044.1 - 4.7 6.4 13.9 6.8 5.8 13.9 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family Herpes_UL32 PF06070.11 CDJ59044.1 - 5.3 4.7 15.3 7.5 4.2 15.3 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ureide_permease PF07168.11 CDJ59044.1 - 5.5 5.6 8.4 0.35 9.6 0.1 2.2 2 0 0 2 2 2 0 Ureide permease Radial_spoke PF04712.12 CDJ59044.1 - 8.2 5.2 37.0 9.1 5.1 16.1 2.1 1 1 1 2 2 2 0 Radial spokehead-like protein EphA2_TM PF14575.6 CDJ59044.1 - 8.5 7.3 9.5 7.4 7.5 0.6 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-RVT PF13966.6 CDJ59047.1 - 0.0022 18.7 0.3 0.0044 17.7 0.3 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Hamartin PF04388.12 CDJ59048.1 - 1.5 7.4 56.9 0.066 11.9 6.2 2.1 2 0 0 2 2 2 0 Hamartin protein Chromo PF00385.24 CDJ59049.1 - 1.9e-07 30.9 0.2 3.4e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BRF1 PF07741.13 CDJ59049.1 - 1.3 9.4 6.8 7.5 7.0 0.5 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain 60KD_IMP PF02096.20 CDJ59049.1 - 3.4 7.5 5.9 5.6 6.8 5.9 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein PhoU PF01895.19 CDJ59050.1 - 0.0079 16.6 1.9 0.0079 16.6 1.9 1.6 2 1 0 2 2 2 1 PhoU domain SlyX PF04102.12 CDJ59050.1 - 0.28 11.8 4.6 1.8 9.3 1.0 2.2 1 1 1 2 2 2 0 SlyX HalX PF08663.10 CDJ59050.1 - 0.4 11.0 5.5 0.47 10.8 3.6 2.1 1 1 1 2 2 2 0 HalX domain ADIP PF11559.8 CDJ59050.1 - 1.1 9.3 8.2 1.3 9.1 8.2 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LCAT PF02450.15 CDJ59051.1 - 6.5e-33 114.4 0.0 2e-32 112.8 0.0 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 CDJ59052.1 - 1.1e-17 64.3 0.3 3.1e-14 53.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59052.1 - 3.7e-09 36.3 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ59052.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ59052.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_methylase PF00145.17 CDJ59053.1 - 1.5e-35 123.2 0.0 3.7e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase GAS PF13851.6 CDJ59054.1 - 1.6e-21 76.6 13.7 1.6e-21 76.6 13.7 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CDJ59054.1 - 0.0022 17.9 11.0 0.0022 17.9 11.0 2.6 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 CDJ59054.1 - 0.021 15.2 6.7 0.021 15.2 6.7 4.1 5 0 0 5 5 5 0 Cell division protein ZapB DUF3695 PF12494.8 CDJ59054.1 - 0.037 13.9 2.3 0.05 13.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3695) Acetyltransf_11 PF13720.6 CDJ59054.1 - 4.4 7.8 8.7 10 6.6 0.9 3.3 1 1 2 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GCP_C_terminal PF04130.13 CDJ59055.1 - 3e-12 46.6 0.7 3e-12 46.6 0.7 3.3 3 1 0 4 4 4 2 Gamma tubulin complex component C-terminal RskA PF10099.9 CDJ59056.1 - 0.0088 16.4 8.9 0.0088 16.4 8.9 5.1 2 2 2 4 4 4 1 Anti-sigma-K factor rskA DUF2201_N PF13203.6 CDJ59059.1 - 1.9 8.1 8.2 2.6 7.6 7.2 1.7 1 1 0 1 1 1 0 Putative metallopeptidase domain RHH_1 PF01402.21 CDJ59060.1 - 0.12 12.4 0.5 0.43 10.6 0.5 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Acyl-CoA_dh_M PF02770.19 CDJ59061.1 - 1.8e-14 53.7 0.0 2.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDJ59061.1 - 1.8e-10 41.5 0.2 2.7e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Ribosomal_L1 PF00687.21 CDJ59062.1 - 5.6e-36 124.2 0.0 9.2e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TAF4 PF05236.14 CDJ59063.1 - 1.9 8.2 5.7 3 7.5 5.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family EF-hand_7 PF13499.6 CDJ59064.1 - 0.11 12.9 0.3 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain pair Isy1 PF06246.12 CDJ59066.1 - 9.2e-30 104.0 5.2 1.2e-29 103.7 5.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family SR-25 PF10500.9 CDJ59066.1 - 0.02 14.5 8.0 0.027 14.1 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ59066.1 - 0.037 14.3 13.9 0.077 13.3 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Band_3_cyto PF07565.13 CDJ59066.1 - 0.082 12.7 5.8 0.11 12.3 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4192 PF13830.6 CDJ59066.1 - 0.12 12.4 2.9 0.15 12.1 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) MDFI PF15316.6 CDJ59066.1 - 2.2 8.4 6.8 3.3 7.8 6.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor BUD22 PF09073.10 CDJ59067.1 - 0.059 12.7 72.1 0.021 14.2 3.5 4.1 2 1 1 3 3 3 0 BUD22 DUF4342 PF14242.6 CDJ59067.1 - 3.7 7.6 0.0 3.7 7.6 0.0 8.9 9 2 1 10 10 10 0 Domain of unknown function (DUF4342) Lactamase_B_2 PF12706.7 CDJ59068.1 - 1e-07 31.7 0.0 1e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ59068.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ndc1_Nup PF09531.10 CDJ59068.1 - 0.066 11.9 21.9 0.004 15.9 16.3 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.9 CDJ59068.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.4 1 1 1 2 2 2 0 Enhancer of polycomb-like Phage_connect_1 PF05135.13 CDJ59068.1 - 2.3 8.8 6.8 0.64 10.6 0.1 2.9 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein Spt20 PF12090.8 CDJ59068.1 - 2.4 7.7 32.1 0.054 13.1 18.4 2.3 2 0 0 2 2 2 0 Spt20 family MMU163 PF17119.5 CDJ59068.1 - 7.7 5.6 12.6 1.3 8.1 0.8 2.6 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Hamartin PF04388.12 CDJ59068.1 - 8 5.0 21.2 14 4.2 21.2 1.3 1 0 0 1 1 1 0 Hamartin protein BRF1 PF07741.13 CDJ59068.1 - 8.3 6.8 11.8 0.57 10.5 6.2 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PikAIV_N PF18605.1 CDJ59069.1 - 0.17 11.5 6.5 0.85 9.3 6.5 2.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Pkinase PF00069.25 CDJ59070.1 - 2.8e-56 190.8 0.0 7.2e-56 189.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59070.1 - 1.9e-28 99.4 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ59070.1 - 1.1e-06 28.2 0.0 2.1e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ59070.1 - 0.09 12.7 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family MCC-bdg_PDZ PF10506.9 CDJ59071.1 - 0.062 13.3 0.2 0.21 11.6 0.2 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Utp13 PF08625.11 CDJ59071.1 - 0.064 13.2 1.1 0.092 12.7 0.2 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain SAM_Exu PF18609.1 CDJ59071.1 - 0.13 12.4 0.3 0.5 10.5 0.3 2.0 1 0 0 1 1 1 0 Exuperantia SAM-like domain TPR_2 PF07719.17 CDJ59072.1 - 0.00017 21.4 0.6 0.00056 19.8 0.6 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ59072.1 - 0.0065 16.2 0.3 0.017 14.9 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ59072.1 - 0.0083 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 TPR repeat DUF4404 PF14357.6 CDJ59072.1 - 0.013 16.1 0.4 0.036 14.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_14 PF13428.6 CDJ59072.1 - 0.02 15.7 1.7 0.081 13.8 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ59072.1 - 0.034 14.2 1.5 0.2 11.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CTU2 PF10288.9 CDJ59072.1 - 0.19 12.0 6.5 1.3 9.3 6.5 2.5 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Macoilin PF09726.9 CDJ59072.1 - 0.25 9.8 0.3 0.39 9.2 0.3 1.3 1 0 0 1 1 1 0 Macoilin family TPR_6 PF13174.6 CDJ59072.1 - 1.6 9.6 4.5 0.88 10.4 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt20 PF12090.8 CDJ59074.1 - 0.00065 19.4 24.2 0.00065 19.4 24.2 13.7 11 2 3 14 14 14 4 Spt20 family UCR_Fe-S_N PF10399.9 CDJ59075.1 - 0.065 12.6 0.3 0.065 12.6 0.3 4.3 4 1 0 4 4 4 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Herpes_pp85 PF04637.12 CDJ59076.1 - 5.3 5.4 10.0 37 2.5 8.2 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CDJ59077.1 - 0.0016 18.1 0.5 0.0016 18.1 0.5 5.0 3 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein CCSAP PF15748.5 CDJ59077.1 - 0.0017 18.6 0.2 0.0017 18.6 0.2 3.6 3 0 0 3 3 3 1 Centriole, cilia and spindle-associated RskA PF10099.9 CDJ59077.1 - 0.0025 18.2 88.9 0.22 11.8 9.4 5.9 3 3 1 4 4 4 3 Anti-sigma-K factor rskA SPX PF03105.19 CDJ59077.1 - 0.0051 16.8 0.0 0.0051 16.8 0.0 2.8 1 1 1 2 2 2 1 SPX domain Spt20 PF12090.8 CDJ59077.1 - 0.0069 16.0 10.2 0.0069 16.0 10.2 5.2 3 1 2 5 5 5 1 Spt20 family DUF755 PF05501.11 CDJ59077.1 - 0.046 14.0 0.3 0.046 14.0 0.3 7.5 5 1 1 6 6 6 0 Domain of unknown function (DUF755) SpoIIIAH PF12685.7 CDJ59077.1 - 2.4 7.9 0.0 2.4 7.9 0.0 4.3 1 1 1 2 2 2 0 SpoIIIAH-like protein PPP4R2 PF09184.11 CDJ59077.1 - 2.7 7.5 23.1 0.45 10.1 15.0 2.9 3 0 0 3 3 3 0 PPP4R2 Ribosomal_60s PF00428.19 CDJ59077.1 - 8.1 7.1 79.4 1.9 9.2 5.7 6.5 6 0 0 6 6 6 0 60s Acidic ribosomal protein DUF2309 PF10070.9 CDJ59078.1 - 0.022 13.1 5.7 1.1 7.4 2.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) TFIIA PF03153.13 CDJ59078.1 - 0.047 13.7 29.6 0.025 14.6 18.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CDJ59078.1 - 0.11 12.6 26.4 0.021 14.9 14.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SR-25 PF10500.9 CDJ59078.1 - 0.5 9.9 29.9 1.7 8.2 18.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CDJ59078.1 - 0.69 8.6 16.0 0.036 12.8 9.3 1.8 2 0 0 2 2 2 0 Presenilin Senescence_reg PF04520.13 CDJ59078.1 - 1 10.2 21.0 1 10.2 1.0 2.2 2 0 0 2 2 2 0 Senescence regulator DUF4457 PF14652.6 CDJ59078.1 - 2 7.6 7.2 0.076 12.3 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) KIAA1430 PF13879.6 CDJ59078.1 - 3.1 8.6 17.1 2.2 9.1 0.9 3.2 3 0 0 3 3 3 0 KIAA1430 homologue FAM60A PF15396.6 CDJ59078.1 - 3.5 7.6 15.9 1.4 8.9 10.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Apt1 PF10351.9 CDJ59078.1 - 5.9 5.6 14.9 0.23 10.3 8.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain AF-4 PF05110.13 CDJ59079.1 - 1.6 6.7 44.6 2.5 6.1 44.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4746 PF15928.5 CDJ59079.1 - 4.4 6.6 23.8 0.28 10.6 9.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF572 PF04502.13 CDJ59079.1 - 6.6 6.2 36.3 10 5.7 36.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.9 CDJ59080.1 - 0.0072 14.7 27.9 0.0069 14.7 27.9 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 RskA PF10099.9 CDJ59080.1 - 0.4 10.9 35.0 1.1 9.5 3.0 3.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Adaptin_binding PF10199.9 CDJ59080.1 - 2.2 8.9 27.3 0.67 10.6 23.6 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SpoIIIAH PF12685.7 CDJ59080.1 - 2.5 7.9 28.5 2.4 7.9 19.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein BSP_II PF05432.11 CDJ59080.1 - 2.8 7.5 16.2 0.076 12.7 9.4 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CRT10 PF08728.10 CDJ59080.1 - 3.1 5.8 12.5 4.5 5.3 12.5 1.3 1 1 0 1 1 1 0 CRT10 Nucleoside_tran PF01733.18 CDJ59080.1 - 6.6 6.0 8.1 11 5.3 8.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter FHIPEP PF00771.20 CDJ59080.1 - 6.7 5.0 13.4 11 4.3 13.4 1.3 1 0 0 1 1 1 0 FHIPEP family RRM_1 PF00076.22 CDJ59082.1 - 0.036 13.9 0.0 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRF1 PF07741.13 CDJ59085.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain AhpC-TSA PF00578.21 CDJ59087.1 - 2.2e-36 124.5 0.0 2.7e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ59087.1 - 3.1e-18 65.9 0.0 3.9e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ59087.1 - 3.6e-13 49.1 0.1 7.6e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CHD5 PF04420.14 CDJ59089.1 - 1.2e-06 28.4 3.6 2.1e-06 27.7 3.6 1.3 1 0 0 1 1 1 1 CHD5-like protein OmpH PF03938.14 CDJ59089.1 - 0.0006 20.2 7.8 0.0011 19.3 7.8 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) CitG PF01874.16 CDJ59089.1 - 0.044 13.4 0.2 0.074 12.7 0.2 1.3 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF2408 PF10303.9 CDJ59089.1 - 0.057 14.0 4.5 0.089 13.4 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Flavi_propep PF01570.17 CDJ59089.1 - 0.15 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide CAP59_mtransfer PF11735.8 CDJ59089.1 - 0.23 11.1 1.9 0.45 10.2 1.9 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Bacillus_HBL PF05791.11 CDJ59089.1 - 1.7 8.4 9.9 1.1 9.1 1.9 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5632 PF18646.1 CDJ59090.1 - 0.02 15.0 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5632) dsDNA_bind PF01984.20 CDJ59090.1 - 0.052 13.8 8.0 0.15 12.3 8.0 1.6 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Serpin PF00079.20 CDJ59091.1 - 8.6e-33 114.1 0.0 9e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ins_P5_2-kin PF06090.12 CDJ59093.1 - 0.001 18.6 3.4 0.001 18.6 3.4 1.5 2 0 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase SUIM_assoc PF16619.5 CDJ59093.1 - 0.042 13.9 0.8 0.042 13.9 0.8 6.0 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ59094.1 - 0.0003 20.5 12.7 0.0003 20.5 12.7 5.0 4 1 2 6 6 6 2 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CDJ59095.1 - 0.46 8.7 57.8 0.087 11.1 38.7 2.4 2 0 0 2 2 2 0 CDC45-like protein zf-RanBP PF00641.18 CDJ59097.1 - 4.8e-15 54.6 20.4 2.9e-09 36.1 5.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-P11 PF03854.14 CDJ59097.1 - 0.0068 16.0 3.8 0.51 10.0 0.2 2.3 2 0 0 2 2 2 2 P-11 zinc finger Spt20 PF12090.8 CDJ59097.1 - 0.031 13.9 8.5 0.04 13.5 8.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ59097.1 - 0.13 12.2 20.4 0.17 11.9 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RecR PF02132.15 CDJ59097.1 - 0.82 9.3 6.5 0.35 10.5 0.9 2.4 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.6 CDJ59097.1 - 2.2 7.8 14.0 3.1 7.3 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PP2C PF00481.21 CDJ59099.1 - 1.2e-63 215.2 0.5 1.7e-52 178.6 0.0 4.0 4 0 0 4 4 4 3 Protein phosphatase 2C DUF3782 PF12644.7 CDJ59099.1 - 0.18 12.0 0.6 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Cytochrom_B561 PF03188.16 CDJ59100.1 - 4e-09 36.7 7.4 8.2e-06 26.0 0.7 2.5 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 DUF5480 PF17576.2 CDJ59100.1 - 0.09 12.8 0.5 0.22 11.5 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Ni_hydr_CYTB PF01292.20 CDJ59100.1 - 0.14 11.7 2.6 0.19 11.3 2.6 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2157 PF09925.9 CDJ59100.1 - 3.5 7.4 9.0 4.9 6.9 0.9 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) SUIM_assoc PF16619.5 CDJ59101.1 - 1.5 8.9 9.4 0.55 10.3 5.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ59101.1 - 1.8 8.2 7.4 0.058 13.0 1.4 1.5 2 0 0 2 2 2 0 Spt20 family 2OG-FeII_Oxy_3 PF13640.6 CDJ59102.1 - 6.2e-08 33.4 0.0 1.2e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Band_7 PF01145.25 CDJ59103.1 - 1.7e-30 106.4 0.1 1.7e-30 106.4 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDJ59103.1 - 2.9e-20 72.1 0.0 8.1e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDJ59103.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Arf PF00025.21 CDJ59104.1 - 1.3e-24 86.6 0.0 1.5e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDJ59104.1 - 0.0033 17.0 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDJ59104.1 - 0.036 13.5 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Autophagy_N PF03986.13 CDJ59105.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Prp18 PF02840.15 CDJ59106.1 - 5e-33 114.2 0.2 5e-33 114.2 0.2 2.8 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 CDJ59106.1 - 7.1e-10 38.3 0.2 1.4e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Sec23_trunk PF04811.15 CDJ59108.1 - 9.1e-54 182.6 0.0 1e-49 169.4 0.0 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ59108.1 - 1.8e-16 60.6 0.0 4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDJ59108.1 - 2.7e-15 56.1 2.6 4.7e-15 55.4 2.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CDJ59108.1 - 6.1e-09 35.6 0.1 1.4e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Pkinase PF00069.25 CDJ59109.1 - 1.9e-42 145.5 0.7 9.2e-34 117.0 0.0 4.4 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59109.1 - 1.4e-17 63.9 0.3 3.6e-15 55.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CDJ59109.1 - 0.0041 16.5 0.2 0.0099 15.2 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ59109.1 - 0.0071 16.3 2.5 0.0071 16.3 2.5 3.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family THOC2_N PF16134.5 CDJ59109.1 - 0.055 12.1 0.1 0.11 11.1 0.1 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus FTA2 PF13095.6 CDJ59109.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.9 3 1 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDJ59109.1 - 8.9 5.0 12.1 7.9 5.1 6.1 3.0 2 1 0 2 2 2 0 Fungal protein kinase DUF4129 PF13559.6 CDJ59110.1 - 0.012 15.9 0.6 0.12 12.7 0.6 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) EF_TS PF00889.19 CDJ59111.1 - 4.5e-27 95.0 0.0 1.4e-26 93.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor TS Ribosomal_S27 PF01599.19 CDJ59112.1 - 1.2e-25 89.4 1.8 2.2e-25 88.6 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CDJ59112.1 - 4.1e-14 52.1 0.1 8.8e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ59112.1 - 4.8e-07 29.5 0.1 1.4e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ59112.1 - 0.0056 16.7 0.5 0.019 15.0 0.0 2.1 3 1 0 3 3 3 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ59112.1 - 0.032 14.7 0.0 0.14 12.6 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CDJ59112.1 - 0.039 14.2 1.2 0.065 13.5 1.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DNA_topoisoIV PF00521.20 CDJ59113.1 - 2e-118 396.0 0.0 4.2e-118 394.9 0.0 1.5 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDJ59113.1 - 8.2e-18 64.9 0.2 3.9e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDJ59114.1 - 1.3e-20 73.6 0.1 2.4e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDJ59114.1 - 2.1e-11 44.3 0.0 1.1e-10 42.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TOPRIM_C PF16898.5 CDJ59114.1 - 2.6e-11 43.9 0.2 5e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM Toprim PF01751.22 CDJ59114.1 - 9.2e-08 32.2 0.0 2.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Nucleoporin_FG PF13634.6 CDJ59116.1 - 1.1e-52 176.8 331.4 3.9e-10 40.4 40.5 10.8 2 2 8 10 10 10 10 Nucleoporin FG repeat region SlyX PF04102.12 CDJ59116.1 - 0.2 12.3 2.3 2.2 9.0 0.3 2.8 3 0 0 3 3 3 0 SlyX Methyltransf_16 PF10294.9 CDJ59119.1 - 1.3e-10 41.3 0.0 4.7e-07 29.7 0.0 3.2 3 0 0 3 3 3 2 Lysine methyltransferase Pkinase PF00069.25 CDJ59120.1 - 1.8e-27 96.4 10.8 3.7e-14 52.7 0.0 3.7 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59120.1 - 3.1e-10 39.8 1.2 9.2e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase SUIM_assoc PF16619.5 CDJ59120.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 18.4 10 4 7 17 17 17 1 Unstructured region C-term to UIM in Ataxin3 Flavokinase PF01687.17 CDJ59121.1 - 6e-23 81.3 0.0 1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase TFIIA PF03153.13 CDJ59123.1 - 3.4 7.6 59.7 1.2 9.0 9.6 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H_2 PF13832.6 CDJ59124.1 - 2.3e-08 34.2 13.7 2.3e-08 34.2 13.7 3.4 2 2 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 CDJ59124.1 - 8.3e-06 25.6 21.3 7.6e-05 22.5 9.1 3.0 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 CDJ59124.1 - 6.4e-05 22.4 7.0 6.4e-05 22.4 7.0 2.8 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDJ59124.1 - 0.0049 16.8 2.6 0.0049 16.8 2.6 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 NAM-associated PF14303.6 CDJ59124.1 - 0.01 16.5 1.2 0.01 16.5 1.2 7.5 7 3 1 8 8 8 0 No apical meristem-associated C-terminal domain zf-HC5HC2H PF13771.6 CDJ59124.1 - 0.02 15.2 21.4 0.011 15.9 14.0 3.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain ketoacyl-synt PF00109.26 CDJ59125.1 - 7.8e-75 251.7 0.0 2.5e-74 250.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CDJ59125.1 - 2.7e-58 196.8 3.6 3e-57 193.4 0.0 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 CDJ59125.1 - 7.1e-44 150.6 0.4 1.2e-43 149.8 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CDJ59125.1 - 1.8e-43 148.9 0.1 2.9e-43 148.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ59125.1 - 2.3e-40 137.3 0.1 4.8e-40 136.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 CDJ59125.1 - 2.2e-15 57.9 0.0 9.4e-09 36.4 0.0 3.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase PP-binding PF00550.25 CDJ59125.1 - 8.9e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 CDJ59125.1 - 9.8e-13 48.2 0.0 6.6e-12 45.5 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 CDJ59125.1 - 2e-10 40.5 0.1 1.6e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ59125.1 - 3.5e-09 36.6 0.0 9.1e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 CDJ59125.1 - 1.4e-08 35.2 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ59125.1 - 0.00019 20.9 0.1 0.00078 18.9 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 CDJ59125.1 - 0.00027 20.8 1.2 0.0007 19.4 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 CDJ59125.1 - 0.00092 18.7 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ59125.1 - 0.0063 16.0 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1015 PF06245.11 CDJ59125.1 - 0.028 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) ACP_syn_III PF08545.10 CDJ59125.1 - 0.059 13.2 0.6 0.2 11.5 0.6 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 CDJ59125.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 4HB PF17947.1 CDJ59125.1 - 0.16 12.1 0.0 0.52 10.4 0.0 1.8 1 0 0 1 1 1 0 Four helical bundle domain DUF2795 PF11387.8 CDJ59127.1 - 0.00019 21.5 1.0 0.00023 21.3 0.1 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF2795) DUF5327 PF17261.2 CDJ59127.1 - 0.0039 17.9 15.8 0.0053 17.5 15.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5327) DUF4746 PF15928.5 CDJ59127.1 - 0.0069 15.8 14.9 0.0081 15.6 14.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DUF4834 PF16118.5 CDJ59127.1 - 0.008 17.1 14.9 0.011 16.7 14.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 CDJ59127.1 - 0.02 14.9 29.0 0.02 14.9 29.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 CDJ59127.1 - 0.022 14.1 8.7 0.024 14.0 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pex14_N PF04695.13 CDJ59127.1 - 0.03 15.0 19.3 0.036 14.7 19.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATAD4 PF15321.6 CDJ59127.1 - 0.076 14.4 7.1 0.085 14.2 7.1 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Suf PF05843.14 CDJ59127.1 - 0.14 12.1 14.3 0.15 12.0 14.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ59127.1 - 0.18 10.8 18.2 0.18 10.8 18.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Baculo_PP31 PF05311.11 CDJ59127.1 - 0.25 10.8 10.7 0.25 10.8 10.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Paf1 PF03985.13 CDJ59127.1 - 0.28 10.2 23.3 0.32 10.0 23.3 1.0 1 0 0 1 1 1 0 Paf1 PIP5K PF01504.18 CDJ59127.1 - 0.28 10.4 7.7 0.23 10.6 7.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CobT PF06213.12 CDJ59127.1 - 0.3 10.4 22.7 0.33 10.3 22.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.17 CDJ59127.1 - 0.31 11.2 12.2 0.34 11.0 12.2 1.1 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ59127.1 - 0.39 10.5 14.3 0.46 10.2 14.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2828 PF11443.8 CDJ59127.1 - 0.39 8.7 12.5 0.38 8.8 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 CDJ59127.1 - 0.47 8.8 5.8 0.42 9.0 5.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 CDJ59127.1 - 0.52 10.5 10.4 0.55 10.4 10.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CCDC53 PF10152.9 CDJ59127.1 - 0.56 10.6 12.8 0.63 10.5 12.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SLC12 PF03522.15 CDJ59127.1 - 0.56 9.2 12.7 0.54 9.2 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Spt20 PF12090.8 CDJ59127.1 - 0.69 9.5 40.7 0.88 9.1 40.7 1.1 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 CDJ59127.1 - 0.71 7.7 14.5 0.71 7.7 14.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CDJ59127.1 - 0.73 9.8 10.1 0.79 9.7 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Peroxin-13_N PF04088.13 CDJ59127.1 - 0.75 10.1 6.0 0.9 9.8 6.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF913 PF06025.12 CDJ59127.1 - 0.99 8.3 9.0 1.1 8.2 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NARP1 PF12569.8 CDJ59127.1 - 1 8.2 15.4 1.1 8.1 15.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MMR1 PF08505.10 CDJ59127.1 - 1 9.6 16.4 1.1 9.5 16.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 CDJ59127.1 - 1.1 9.3 20.7 1.3 9.0 20.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Eapp_C PF10238.9 CDJ59127.1 - 1.2 9.3 16.0 1.5 8.9 16.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FYDLN_acid PF09538.10 CDJ59127.1 - 1.2 9.9 11.2 1.7 9.4 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Dynamin_N PF00350.23 CDJ59127.1 - 1.3 9.1 7.2 1.4 8.9 7.2 1.1 1 0 0 1 1 1 0 Dynamin family Peptidase_S49_N PF08496.10 CDJ59127.1 - 1.4 9.0 11.4 1.6 8.8 11.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CLN3 PF02487.17 CDJ59127.1 - 1.5 7.8 9.6 1.6 7.7 9.6 1.0 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ59127.1 - 1.5 8.6 16.0 1.5 8.5 16.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 CDJ59127.1 - 1.6 7.7 7.8 1.6 7.7 7.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Spem1 PF15670.5 CDJ59127.1 - 1.6 8.2 16.0 2 7.9 16.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 SpoIIP PF07454.11 CDJ59127.1 - 1.7 8.1 18.0 2.1 7.7 18.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ59127.1 - 1.7 7.3 9.2 1.6 7.3 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 CDJ59127.1 - 1.7 7.9 16.8 1.9 7.8 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EOS1 PF12326.8 CDJ59127.1 - 1.7 8.5 6.3 1.7 8.5 6.3 1.1 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 CDJ59127.1 - 1.8 7.3 18.7 2 7.1 18.7 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ59127.1 - 2.2 8.3 14.0 2.7 8.0 14.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ59127.1 - 2.3 6.9 11.2 2.4 6.9 11.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter BORG_CEP PF14957.6 CDJ59127.1 - 2.8 9.1 11.1 3.6 8.8 11.1 1.1 1 0 0 1 1 1 0 Cdc42 effector RPA43_OB PF17875.1 CDJ59127.1 - 2.8 8.6 11.7 3.5 8.3 11.7 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I NPR3 PF03666.13 CDJ59127.1 - 3 6.6 14.2 3.3 6.4 14.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pannexin_like PF12534.8 CDJ59127.1 - 3.4 6.7 10.3 4.1 6.4 10.3 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Hid1 PF12722.7 CDJ59127.1 - 3.5 5.7 14.8 3.5 5.6 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.6 CDJ59127.1 - 3.5 8.0 11.1 4.5 7.6 11.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term F-protein PF00469.20 CDJ59127.1 - 3.9 7.0 15.4 4.8 6.7 15.4 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef MAJIN PF15077.6 CDJ59127.1 - 4 7.2 10.8 4.3 7.1 10.8 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1682 PF07946.14 CDJ59127.1 - 4.7 6.3 20.6 5 6.2 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 CDJ59127.1 - 4.9 6.8 12.8 5.7 6.6 12.8 1.1 1 0 0 1 1 1 0 Connexin Caldesmon PF02029.15 CDJ59127.1 - 5.1 5.8 28.7 5.8 5.6 28.7 1.1 1 0 0 1 1 1 0 Caldesmon HCO3_cotransp PF00955.21 CDJ59127.1 - 5.5 5.7 4.6 5.9 5.6 4.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family SpecificRecomb PF10136.9 CDJ59127.1 - 5.7 5.1 10.3 6.1 5.0 10.3 1.0 1 0 0 1 1 1 0 Site-specific recombinase Rtf2 PF04641.12 CDJ59127.1 - 5.8 6.2 19.1 7.8 5.8 19.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Gti1_Pac2 PF09729.9 CDJ59127.1 - 6.7 6.8 13.1 8.4 6.4 13.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Serinc PF03348.15 CDJ59127.1 - 7.9 5.3 10.1 8.1 5.2 10.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.15 CDJ59127.1 - 8.1 7.0 9.4 9.6 6.8 9.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_TM PF03929.16 CDJ59127.1 - 8.2 6.0 7.8 8.3 6.0 7.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region EIIBC-GUT_N PF03612.14 CDJ59127.1 - 8.7 6.0 14.2 11 5.7 14.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Folliculin PF11704.8 CDJ59127.1 - 9.2 6.1 12.7 11 5.8 12.7 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TFIIA PF03153.13 CDJ59128.1 - 0.027 14.5 18.9 0.032 14.2 10.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NAD_kinase PF01513.21 CDJ59128.1 - 0.059 12.6 0.0 0.45 9.7 0.0 2.4 2 0 0 2 2 2 0 ATP-NAD kinase Presenilin PF01080.17 CDJ59128.1 - 0.52 9.0 1.5 0.51 9.0 0.1 1.7 2 0 0 2 2 2 0 Presenilin DAGK_cat PF00781.24 CDJ59128.1 - 0.57 9.8 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF2722 PF10846.8 CDJ59128.1 - 0.6 9.0 12.1 0.11 11.4 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) KH_1 PF00013.29 CDJ59129.1 - 3.4e-16 58.8 0.0 4.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDJ59129.1 - 0.0062 16.4 0.3 2.1 8.3 0.0 2.5 2 0 0 2 2 2 2 KH domain SUIM_assoc PF16619.5 CDJ59129.1 - 0.007 16.4 19.2 0.034 14.2 7.7 3.8 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 KH_2 PF07650.17 CDJ59129.1 - 0.0074 16.1 0.0 0.099 12.5 0.0 2.2 2 0 0 2 2 2 1 KH domain Lin-8 PF03353.15 CDJ59129.1 - 0.66 9.5 12.8 0.03 13.9 7.3 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TMEM51 PF15345.6 CDJ59129.1 - 1.2 8.9 11.2 1.4 8.7 8.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 SAPIS-gp6 PF16722.5 CDJ59129.1 - 2.6 8.5 6.7 21 5.6 2.5 2.6 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus GREB1 PF15782.5 CDJ59129.1 - 3.4 4.7 17.7 0.026 11.7 9.4 1.7 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer MPM1 PF17234.2 CDJ59129.1 - 5.6 7.2 9.8 0.4 10.9 4.6 1.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Utp14 PF04615.13 CDJ59130.1 - 0.00021 20.0 26.3 0.00021 20.0 26.3 3.3 2 1 0 2 2 2 1 Utp14 protein Pro_isomerase PF00160.21 CDJ59131.1 - 1.4e-28 100.2 0.0 4e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ThiD2 PF17792.1 CDJ59131.1 - 0.85 10.1 14.4 0.094 13.2 5.2 2.9 3 0 0 3 3 3 0 ThiD2 family PAC1 PF16094.5 CDJ59131.1 - 7 5.7 7.0 12 5.0 7.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AP2 PF00847.20 CDJ59132.1 - 5.3e-10 39.4 2.0 7e-06 26.2 0.5 4.5 5 0 0 5 5 5 2 AP2 domain Baculo_VP91_N PF08475.10 CDJ59135.1 - 0.077 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal CBM_14 PF01607.24 CDJ59135.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain SARAF PF06682.12 CDJ59135.1 - 3 7.4 11.7 4.3 6.9 0.2 2.6 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis V_ATPase_I PF01496.19 CDJ59135.1 - 4.1 5.2 7.3 6.9 4.5 7.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SelP_N PF04592.14 CDJ59135.1 - 5.2 6.4 37.9 0.13 11.6 31.5 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.22 CDJ59135.1 - 6.3 5.9 14.9 6.8 5.8 13.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2052 PF09747.9 CDJ59137.1 - 1.9e-06 28.2 15.6 0.0025 18.0 8.9 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF2722 PF10846.8 CDJ59137.1 - 7.9e-06 25.1 8.6 7.9e-06 25.1 8.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) FAM176 PF14851.6 CDJ59137.1 - 1.2e-05 25.1 13.3 0.0045 16.6 7.4 2.3 2 0 0 2 2 2 2 FAM176 family EPL1 PF10513.9 CDJ59137.1 - 2.5e-05 24.7 13.1 0.019 15.3 1.7 2.5 2 0 0 2 2 2 2 Enhancer of polycomb-like DUF4834 PF16118.5 CDJ59137.1 - 3.5e-05 24.7 21.6 0.02 15.8 5.3 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) RNase_H2_suC PF08615.11 CDJ59137.1 - 0.00013 22.1 3.9 0.22 11.7 0.4 2.3 2 0 0 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RskA PF10099.9 CDJ59137.1 - 0.00017 21.9 48.4 0.0017 18.7 14.7 4.2 1 1 3 4 4 3 2 Anti-sigma-K factor rskA MecA PF05389.12 CDJ59137.1 - 0.00034 20.3 13.3 0.0053 16.4 0.8 2.2 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) HNOBA PF07701.14 CDJ59137.1 - 0.00041 19.9 6.5 0.099 12.1 1.5 2.2 2 0 0 2 2 2 2 Heme NO binding associated Tim54 PF11711.8 CDJ59137.1 - 0.00047 19.1 19.4 0.067 12.0 11.3 2.3 2 0 0 2 2 2 2 Inner membrane protein import complex subunit Tim54 Spem1 PF15670.5 CDJ59137.1 - 0.00048 19.8 9.8 0.061 12.9 0.1 2.3 2 0 0 2 2 2 1 Spermatid maturation protein 1 DUF4611 PF15387.6 CDJ59137.1 - 0.00048 20.3 11.5 0.029 14.6 6.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 CDJ59137.1 - 0.00078 17.7 3.9 0.00078 17.7 3.9 3.0 2 1 1 3 3 1 1 Sporozoite P67 surface antigen SLC12 PF03522.15 CDJ59137.1 - 0.00084 18.5 11.2 0.018 14.1 0.6 2.1 2 0 0 2 2 2 2 Solute carrier family 12 CD20 PF04103.15 CDJ59137.1 - 0.00097 19.2 2.2 0.012 15.7 0.1 2.4 2 0 0 2 2 2 1 CD20-like family AAA_11 PF13086.6 CDJ59137.1 - 0.00098 19.0 10.8 0.076 12.8 1.4 2.3 2 0 0 2 2 2 2 AAA domain CNDH2_C PF16858.5 CDJ59137.1 - 0.0011 18.9 13.2 0.084 12.7 4.1 2.1 2 0 0 2 2 2 2 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3464 PF11947.8 CDJ59137.1 - 0.0013 18.5 18.0 0.11 12.2 5.6 2.6 2 0 0 2 2 2 2 Photosynthesis affected mutant 68 MMR1 PF08505.10 CDJ59137.1 - 0.0017 18.7 25.7 0.12 12.7 8.5 2.4 2 0 0 2 2 2 2 Mitochondrial Myo2 receptor-related protein OATP PF03137.20 CDJ59137.1 - 0.0021 16.4 9.7 0.0074 14.6 0.7 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DcuA_DcuB PF03605.14 CDJ59137.1 - 0.0026 16.7 4.4 0.0026 16.7 4.4 2.5 1 1 1 2 2 1 1 Anaerobic c4-dicarboxylate membrane transporter RXT2_N PF08595.11 CDJ59137.1 - 0.0029 17.7 14.4 0.028 14.4 6.5 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal CDC45 PF02724.14 CDJ59137.1 - 0.0031 15.9 16.2 0.052 11.9 1.5 2.1 2 0 0 2 2 2 2 CDC45-like protein Nop14 PF04147.12 CDJ59137.1 - 0.0033 15.7 4.0 0.0033 15.7 4.0 2.1 2 0 0 2 2 2 1 Nop14-like family RPA43_OB PF17875.1 CDJ59137.1 - 0.0035 18.0 11.6 0.34 11.5 0.5 2.5 2 0 0 2 2 2 2 RPA43 OB domain in RNA Pol I EOS1 PF12326.8 CDJ59137.1 - 0.0042 17.0 10.3 0.0098 15.8 2.2 2.3 2 0 0 2 2 2 1 N-glycosylation protein SpoIIP PF07454.11 CDJ59137.1 - 0.0047 16.4 20.8 0.16 11.4 7.7 2.2 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) RPN2_C PF18004.1 CDJ59137.1 - 0.0047 16.9 19.8 0.15 12.0 8.6 2.3 2 0 0 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain TMEM51 PF15345.6 CDJ59137.1 - 0.0049 16.7 1.5 0.0049 16.7 1.5 2.5 2 0 0 2 2 2 1 Transmembrane protein 51 DUF4471 PF14740.6 CDJ59137.1 - 0.005 16.1 9.3 0.059 12.6 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) BSP_II PF05432.11 CDJ59137.1 - 0.0054 16.5 8.2 0.0054 16.5 8.2 2.6 2 1 1 3 3 1 1 Bone sialoprotein II (BSP-II) Connexin PF00029.19 CDJ59137.1 - 0.0057 16.5 17.9 0.019 14.7 2.2 2.2 2 0 0 2 2 2 1 Connexin FAM76 PF16046.5 CDJ59137.1 - 0.0068 15.8 16.8 0.2 11.0 5.3 2.1 2 0 0 2 2 2 2 FAM76 protein PI3K_1B_p101 PF10486.9 CDJ59137.1 - 0.0086 13.9 10.3 0.1 10.4 2.2 2.1 2 0 0 2 2 2 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Vfa1 PF08432.10 CDJ59137.1 - 0.01 16.2 20.1 0.22 11.8 2.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Eapp_C PF10238.9 CDJ59137.1 - 0.01 15.9 19.8 0.42 10.7 6.6 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein eIF-3_zeta PF05091.12 CDJ59137.1 - 0.011 14.8 23.5 0.089 11.8 8.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4820 PF16091.5 CDJ59137.1 - 0.012 15.0 18.8 0.1 12.0 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Spt20 PF12090.8 CDJ59137.1 - 0.013 15.1 18.0 0.013 15.1 18.0 3.0 3 0 0 3 3 2 0 Spt20 family Pox_Ag35 PF03286.14 CDJ59137.1 - 0.018 14.9 11.9 0.13 12.1 7.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM60A PF15396.6 CDJ59137.1 - 0.023 14.7 12.4 0.062 13.3 0.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A FmiP_Thoc5 PF09766.9 CDJ59137.1 - 0.025 13.9 24.3 0.12 11.6 5.2 2.5 3 0 0 3 3 2 0 Fms-interacting protein/Thoc5 TCP PF03634.13 CDJ59137.1 - 0.027 15.0 21.7 0.14 12.7 6.7 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF913 PF06025.12 CDJ59137.1 - 0.028 13.4 14.8 0.22 10.5 6.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FHIPEP PF00771.20 CDJ59137.1 - 0.036 12.5 14.8 0.17 10.3 4.3 2.1 2 0 0 2 2 2 0 FHIPEP family Orf78 PF06024.12 CDJ59137.1 - 0.038 14.3 15.9 1 9.7 3.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Mak16 PF04874.14 CDJ59137.1 - 0.04 14.5 17.8 1.7 9.3 0.3 2.5 2 0 0 2 2 2 0 Mak16 protein C-terminal region Tom22 PF04281.13 CDJ59137.1 - 0.044 13.6 13.6 0.12 12.2 3.2 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF4647 PF15504.6 CDJ59137.1 - 0.055 12.6 18.6 0.1 11.7 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Radial_spoke PF04712.12 CDJ59137.1 - 0.056 12.4 14.2 0.058 12.3 5.4 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein CobT PF06213.12 CDJ59137.1 - 0.058 12.8 37.6 0.0099 15.3 14.1 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 CDJ59137.1 - 0.06 13.7 14.1 0.68 10.3 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CSG2 PF16965.5 CDJ59137.1 - 0.06 12.3 12.2 0.19 10.6 1.8 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator TRAP_alpha PF03896.16 CDJ59137.1 - 0.061 12.5 11.9 0.92 8.7 7.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2235 PF09994.9 CDJ59137.1 - 0.062 12.6 9.4 0.28 10.5 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PA26 PF04636.13 CDJ59137.1 - 0.064 12.2 11.1 0.26 10.1 0.7 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Serinc PF03348.15 CDJ59137.1 - 0.069 12.1 12.6 0.57 9.1 2.8 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Afi1 PF07792.12 CDJ59137.1 - 0.076 13.5 20.7 1.1 9.7 8.9 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.19 CDJ59137.1 - 0.076 10.9 21.2 0.1 10.5 2.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2956 PF11169.8 CDJ59137.1 - 0.08 13.1 25.0 1 9.6 10.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) MRNIP PF15749.5 CDJ59137.1 - 0.088 13.5 32.0 0.051 14.3 10.7 2.3 2 0 0 2 2 2 0 MRN-interacting protein G0-G1_switch_2 PF15103.6 CDJ59137.1 - 0.09 13.2 21.1 0.12 12.8 6.6 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 Peroxin-13_N PF04088.13 CDJ59137.1 - 0.098 12.9 11.5 0.69 10.2 1.8 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region BSMAP PF12280.8 CDJ59137.1 - 0.11 12.7 14.7 0.18 12.0 3.6 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein PRC2_HTH_1 PF18118.1 CDJ59137.1 - 0.12 13.1 21.3 1.5 9.7 4.2 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF3169 PF11368.8 CDJ59137.1 - 0.13 11.8 4.9 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) LAP1C PF05609.12 CDJ59137.1 - 0.17 11.0 25.4 0.44 9.6 10.3 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 CDJ59137.1 - 0.2 9.8 17.4 0.53 8.4 2.2 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF1266 PF06889.11 CDJ59137.1 - 0.21 11.6 11.0 0.45 10.5 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF5523 PF17661.1 CDJ59137.1 - 0.23 11.1 25.2 0.69 9.6 11.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) CLN3 PF02487.17 CDJ59137.1 - 0.26 10.3 14.5 0.21 10.6 1.0 2.2 2 0 0 2 2 2 0 CLN3 protein MAT1 PF06391.13 CDJ59137.1 - 0.28 11.0 27.9 0.73 9.6 9.6 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Dynamin_N PF00350.23 CDJ59137.1 - 0.3 11.1 10.2 0.77 9.8 0.6 2.3 2 0 0 2 2 2 0 Dynamin family FAM91_C PF14648.6 CDJ59137.1 - 0.31 9.8 12.5 0.55 9.0 1.7 2.1 2 0 0 2 2 2 0 FAM91 C-terminus Zip PF02535.22 CDJ59137.1 - 0.36 10.0 11.8 1 8.5 3.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter IPP-2 PF04979.14 CDJ59137.1 - 0.36 11.6 21.8 3 8.6 8.1 2.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) XRN_M PF17846.1 CDJ59137.1 - 0.37 9.7 11.4 1.3 7.8 0.6 2.2 2 0 0 2 2 2 0 Xrn1 helical domain XAP5 PF04921.14 CDJ59137.1 - 0.37 10.6 17.2 1.5 8.6 2.2 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator Rrp15p PF07890.12 CDJ59137.1 - 0.37 11.1 22.5 1.3 9.4 7.9 2.7 2 0 0 2 2 2 0 Rrp15p ESM4 PF15952.5 CDJ59137.1 - 0.38 11.2 27.0 0.66 10.4 9.7 2.3 2 0 0 2 2 2 0 Enhancer of split M4 family Anoctamin PF04547.12 CDJ59137.1 - 0.38 9.5 3.7 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel Mlh1_C PF16413.5 CDJ59137.1 - 0.4 10.0 16.5 0.34 10.2 1.9 2.2 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus GEN1_C PF18380.1 CDJ59137.1 - 0.4 11.6 15.6 3 8.8 0.4 2.9 3 0 0 3 3 2 0 Holliday junction resolvase Gen1 C-terminal domain MFS_Mycoplasma PF07672.13 CDJ59137.1 - 0.4 9.9 0.0 0.4 9.9 0.0 1.9 2 0 0 2 2 1 0 Mycoplasma MFS transporter DUF1980 PF09323.10 CDJ59137.1 - 0.4 10.6 14.5 0.85 9.5 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2828 PF11443.8 CDJ59137.1 - 0.41 8.7 17.2 0.062 11.4 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) MAM33 PF02330.16 CDJ59137.1 - 0.42 10.5 22.0 0.56 10.1 2.7 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein NOA36 PF06524.12 CDJ59137.1 - 0.44 9.8 13.4 0.2 10.9 7.5 2.1 2 0 0 2 2 2 0 NOA36 protein TMEM208_SND2 PF05620.11 CDJ59137.1 - 0.52 10.1 13.3 1.7 8.4 4.9 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Conotoxin PF02950.17 CDJ59137.1 - 0.52 11.4 18.2 2.1 9.4 5.8 3.0 2 0 0 2 2 2 0 Conotoxin Glt_symporter PF03616.14 CDJ59137.1 - 0.59 8.8 6.6 0.33 9.6 0.2 2.4 2 0 0 2 2 2 0 Sodium/glutamate symporter DNA_pol_phi PF04931.13 CDJ59137.1 - 0.65 8.0 17.2 0.0097 14.1 5.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi PPL5 PF18168.1 CDJ59137.1 - 0.66 9.2 16.4 0.84 8.9 5.0 2.3 2 0 0 2 2 2 0 Prim-pol family 5 Pkinase_fungal PF17667.1 CDJ59137.1 - 0.69 8.6 8.1 0.67 8.7 1.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase PTPRCAP PF15713.5 CDJ59137.1 - 0.7 10.2 35.6 0.69 10.2 4.2 3.3 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated AIF_C PF14721.6 CDJ59137.1 - 0.73 10.2 20.0 0.11 12.8 1.0 2.7 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TMEM82 PF15816.5 CDJ59137.1 - 0.77 8.7 5.3 3.3 6.6 0.6 2.3 2 0 0 2 2 2 0 Transmembrane protein 82 NST1 PF13945.6 CDJ59137.1 - 0.88 9.6 33.2 0.079 13.1 8.9 2.6 3 0 0 3 3 2 0 Salt tolerance down-regulator Cellulose_synt PF03552.14 CDJ59137.1 - 1 7.8 7.5 3.2 6.1 0.5 2.1 2 0 0 2 2 2 0 Cellulose synthase NEMP PF10225.9 CDJ59137.1 - 1.1 8.9 10.9 3.3 7.3 1.2 2.2 2 0 0 2 2 2 0 NEMP family Pinin_SDK_memA PF04696.13 CDJ59137.1 - 1.1 9.3 42.3 3.3 7.8 18.2 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4199 PF13858.6 CDJ59137.1 - 1.2 9.5 14.2 0.81 10.1 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3405 PF11885.8 CDJ59137.1 - 1.4 7.5 17.5 0.21 10.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) Peptidase_S64 PF08192.11 CDJ59137.1 - 1.4 7.3 13.2 0.83 8.1 1.4 2.1 2 0 0 2 2 2 0 Peptidase family S64 LMBR1 PF04791.16 CDJ59137.1 - 1.5 7.7 6.8 0.17 10.7 0.2 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein AbLIM_anchor PF16182.5 CDJ59137.1 - 1.7 8.4 15.1 0.38 10.5 0.4 2.2 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Paf1 PF03985.13 CDJ59137.1 - 1.7 7.5 31.6 0.37 9.7 12.6 2.2 2 0 0 2 2 2 0 Paf1 DUF702 PF05142.12 CDJ59137.1 - 1.8 9.0 25.4 1.1 9.8 3.6 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF702) RAB3GAP2_N PF14655.6 CDJ59137.1 - 1.9 7.6 14.3 2.2 7.4 4.3 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DnaJ-X PF14308.6 CDJ59137.1 - 2 7.8 18.0 3.5 7.0 3.1 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing Nha1_C PF08619.10 CDJ59137.1 - 2.2 7.4 27.8 0.093 11.9 9.4 2.5 3 0 0 3 3 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus LRRC37AB_C PF14914.6 CDJ59137.1 - 2.2 8.2 21.0 0.41 10.6 5.3 2.2 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF2370 PF10176.9 CDJ59137.1 - 2.5 7.7 9.3 6.9 6.2 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) ALMT PF11744.8 CDJ59137.1 - 2.5 6.9 17.6 2 7.2 4.8 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Sin_N PF04801.13 CDJ59137.1 - 2.5 7.2 30.9 0.091 12.0 7.1 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region AIM3 PF17096.5 CDJ59137.1 - 2.6 9.0 25.2 0.52 11.3 10.6 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Rgp1 PF08737.10 CDJ59137.1 - 2.9 7.0 14.6 4 6.5 3.6 2.1 2 0 0 2 2 2 0 Rgp1 TLP-20 PF06088.11 CDJ59137.1 - 3.1 7.7 18.0 0.48 10.3 6.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HCO3_cotransp PF00955.21 CDJ59137.1 - 3.4 6.4 10.2 0.57 8.9 1.3 2.1 2 0 0 2 2 2 0 HCO3- transporter family Membralin PF09746.9 CDJ59137.1 - 3.4 6.6 12.5 6 5.8 1.2 2.2 2 0 0 2 2 2 0 Tumour-associated protein CENP-B_dimeris PF09026.10 CDJ59137.1 - 4 7.9 10.2 1.5 9.3 7.1 1.8 2 0 0 2 2 1 0 Centromere protein B dimerisation domain EIIBC-GUT_N PF03612.14 CDJ59137.1 - 4 7.2 25.2 0.32 10.7 4.9 2.8 3 0 0 3 3 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 CDJ59137.1 - 4.2 8.2 15.2 1.2 9.9 0.9 2.6 3 0 0 3 3 2 0 Histone deacetylation protein Rxt3 Thg1C PF14413.6 CDJ59137.1 - 4.3 7.5 21.5 5.8 7.1 4.4 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain CDC27 PF09507.10 CDJ59137.1 - 4.5 6.6 42.9 0.15 11.4 18.7 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.19 CDJ59137.1 - 4.5 6.1 15.0 2.2 7.1 2.0 2.4 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein DUF4746 PF15928.5 CDJ59137.1 - 4.5 6.6 26.5 0.36 10.2 10.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Peptidase_S15 PF02129.18 CDJ59137.1 - 4.7 6.7 23.5 0.028 14.0 5.5 2.6 3 0 0 3 3 2 0 X-Pro dipeptidyl-peptidase (S15 family) RuvC_III PF18541.1 CDJ59137.1 - 4.7 7.1 22.7 6.1 6.8 7.8 2.4 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 DUF3506 PF12014.8 CDJ59137.1 - 4.9 7.2 11.3 2 8.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Activator_LAG-3 PF11498.8 CDJ59137.1 - 5 6.0 52.2 0.031 13.2 25.5 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 O-antigen_lig PF13425.6 CDJ59137.1 - 5.5 5.7 11.2 8.8 5.0 5.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein UPF0239 PF06783.11 CDJ59137.1 - 5.8 7.2 16.3 0.28 11.4 2.4 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) PH_4 PF15404.6 CDJ59137.1 - 6.3 6.6 17.0 8.2 6.2 5.5 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain YABBY PF04690.13 CDJ59137.1 - 6.3 7.3 17.9 11 6.6 5.1 2.5 2 0 0 2 2 2 0 YABBY protein TRM13 PF05206.14 CDJ59137.1 - 6.4 6.2 17.5 0.69 9.4 2.4 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 SUFU_C PF12470.8 CDJ59137.1 - 6.7 6.7 13.0 5.6 7.0 2.0 2.3 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain UBN_AB PF14075.6 CDJ59137.1 - 6.7 6.4 24.6 2.9 7.6 4.8 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Ctr PF04145.15 CDJ59137.1 - 7.9 7.1 18.3 2.2 8.9 3.4 2.6 3 0 0 3 3 2 0 Ctr copper transporter family DUF2126 PF09899.9 CDJ59137.1 - 8.2 4.3 14.0 0.68 7.9 1.5 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF3381 PF11861.8 CDJ59137.1 - 8.4 6.2 34.2 3.1 7.6 14.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TERB2 PF15101.6 CDJ59137.1 - 8.6 6.4 36.6 1.8 8.6 10.2 2.5 3 0 0 3 3 2 0 Telomere-associated protein TERB2 BRF1 PF07741.13 CDJ59137.1 - 8.7 6.8 27.4 0.95 9.8 6.0 3.3 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DUF4638 PF15472.6 CDJ59137.1 - 9.2 5.9 17.0 9.1 5.9 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) CFIA_Pcf11 PF11526.8 CDJ59137.1 - 9.5 6.8 26.3 0.33 11.5 3.3 3.4 3 0 0 3 3 2 0 Subunit of cleavage factor IA Pcf11 Med24_N PF11277.8 CDJ59137.1 - 9.5 4.1 13.2 2.8 5.9 4.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 24 N-terminal Tau95_N PF17682.1 CDJ59137.1 - 9.8 6.4 12.7 1.7 8.8 1.5 2.4 2 0 0 2 2 2 0 Tau95 Triple barrel domain Scs3p PF10261.9 CDJ59138.1 - 1.6 8.2 5.4 0.36 10.3 0.4 2.2 2 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM AP2 PF00847.20 CDJ59139.1 - 2.7e-09 37.1 1.2 4.4e-05 23.6 0.1 3.4 2 0 0 2 2 2 2 AP2 domain RskA PF10099.9 CDJ59139.1 - 0.0044 17.3 4.3 0.0044 17.3 4.3 13.2 6 4 1 8 8 8 1 Anti-sigma-K factor rskA MCU PF04678.13 CDJ59139.1 - 9.4 6.3 25.6 4.7 7.3 5.5 3.5 3 0 0 3 3 3 0 Mitochondrial calcium uniporter HGTP_anticodon PF03129.20 CDJ59142.1 - 2e-06 27.9 1.3 2e-06 27.9 1.3 2.6 2 1 0 2 2 2 1 Anticodon binding domain PIP5K PF01504.18 CDJ59142.1 - 0.00011 21.6 0.0 0.00011 21.6 0.0 4.1 3 2 0 3 3 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Macoilin PF09726.9 CDJ59142.1 - 0.00062 18.5 2.5 0.00062 18.5 2.5 4.8 4 1 1 5 5 5 3 Macoilin family Presenilin PF01080.17 CDJ59142.1 - 0.00063 18.6 5.1 0.00063 18.6 5.1 4.1 4 0 0 4 4 4 2 Presenilin UNC-79 PF14776.6 CDJ59142.1 - 0.0036 16.1 0.2 0.0036 16.1 0.2 2.5 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 SPX PF03105.19 CDJ59142.1 - 0.0049 16.8 0.4 0.0049 16.8 0.4 3.8 3 1 0 3 3 3 1 SPX domain MecA PF05389.12 CDJ59142.1 - 0.0084 15.8 1.7 0.0084 15.8 1.7 4.1 4 0 0 4 4 4 1 Negative regulator of genetic competence (MecA) SUIM_assoc PF16619.5 CDJ59142.1 - 0.0086 16.1 1.4 0.0086 16.1 1.4 6.0 4 2 0 4 4 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ59142.1 - 0.013 15.5 77.0 0.016 15.2 20.8 3.9 4 2 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit FKS1_dom1 PF14288.6 CDJ59142.1 - 3.1 8.1 8.1 2.3 8.5 2.4 3.1 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF913 PF06025.12 CDJ59142.1 - 6.2 5.7 30.7 1.2 8.1 0.4 4.7 5 0 0 5 5 5 0 Domain of Unknown Function (DUF913) Myosin_head PF00063.21 CDJ59143.1 - 3.1e-96 323.2 1.0 3.5e-96 323.0 1.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CDJ59143.1 - 8.9e-06 25.4 1.6 1.7e-05 24.6 1.6 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CDJ59143.1 - 0.00074 19.9 0.0 0.0018 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDJ59143.1 - 0.0049 17.1 0.1 0.0092 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CDJ59143.1 - 0.019 15.0 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 CDJ59143.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ59143.1 - 0.059 12.6 0.1 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 CDJ59143.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CDJ59143.1 - 0.12 12.3 1.3 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 NACHT domain SH3_19 PF18597.1 CDJ59143.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain T2SSE PF00437.20 CDJ59143.1 - 0.18 10.9 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CDJ59143.1 - 0.33 11.4 1.7 0.65 10.4 0.1 2.1 2 0 0 2 2 2 0 RNA helicase TFIIA PF03153.13 CDJ59144.1 - 0.0077 16.3 25.8 0.0099 15.9 25.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ59144.1 - 0.048 13.6 11.4 0.06 13.3 11.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CDJ59144.1 - 0.16 10.9 6.2 0.19 10.6 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CDJ59144.1 - 1.8 7.3 6.8 2.3 6.9 6.8 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ59144.1 - 1.9 8.2 6.7 3 7.6 6.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 G0-G1_switch_2 PF15103.6 CDJ59144.1 - 6.5 7.2 7.3 15 6.1 7.3 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 UPF0560 PF10577.9 CDJ59144.1 - 7.8 4.9 14.3 12 4.3 14.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 tRNA-synt_1 PF00133.22 CDJ59145.1 - 2.7e-17 62.3 0.0 7.9e-09 34.3 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ59145.1 - 4.3e-08 32.3 0.0 1e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) Tmemb_9 PF05434.11 CDJ59145.1 - 0.26 11.2 1.5 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 TMEM9 DUF4748 PF15932.5 CDJ59145.1 - 6.3 6.6 6.4 14 5.5 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Pterin_bind PF00809.22 CDJ59146.1 - 4.1e-53 180.6 0.4 5.9e-53 180.0 0.4 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CDJ59146.1 - 3.7e-25 88.6 0.0 7.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Usp PF00582.26 CDJ59146.1 - 0.066 13.7 0.0 0.16 12.5 0.0 1.7 1 1 0 1 1 1 0 Universal stress protein family ScsC_N PF18312.1 CDJ59146.1 - 0.15 11.9 0.4 0.69 9.8 0.4 2.2 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Glyco_transf_88 PF16849.5 CDJ59146.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 REPA_OB_2 PF16900.5 CDJ59147.1 - 2e-20 72.5 0.0 1.9e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CDJ59147.1 - 0.0098 15.9 0.0 0.16 12.0 0.0 2.5 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Presenilin PF01080.17 CDJ59147.1 - 9 4.9 6.9 4.6 5.9 1.9 2.0 2 0 0 2 2 2 0 Presenilin eIF-3c_N PF05470.12 CDJ59148.1 - 2.9e-134 448.6 18.0 3.9e-133 444.9 18.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDJ59148.1 - 3.9e-11 43.4 0.2 2.3e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 PCI domain DNA_photolyase PF00875.18 CDJ59149.1 - 1.5e-09 38.1 1.2 5.2e-09 36.3 1.2 1.8 1 1 0 1 1 1 1 DNA photolyase Methyltransf_3 PF01596.17 CDJ59149.1 - 0.062 12.5 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DIM1 PF02966.16 CDJ59150.1 - 2e-46 157.1 0.7 2.2e-46 156.9 0.7 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Adaptin_N PF01602.20 CDJ59151.1 - 6.1e-90 302.3 1.3 6.8e-84 282.3 0.2 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDJ59151.1 - 1.2e-14 54.6 0.0 3.1e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDJ59151.1 - 1.7e-06 28.2 0.1 0.025 14.6 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ59151.1 - 0.00046 20.5 4.7 0.0048 17.3 0.2 5.6 6 2 2 8 8 8 2 HEAT repeats HEAT PF02985.22 CDJ59151.1 - 0.002 18.2 3.8 0.41 11.0 0.1 5.7 5 1 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 CDJ59151.1 - 0.029 14.5 1.3 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RVT_1 PF00078.27 CDJ59152.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDJ59152.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 CDJ59153.1 - 1.4e-19 70.5 0.0 3.4e-10 39.8 0.0 4.3 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59153.1 - 0.0066 15.8 0.0 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDJ59153.1 - 0.12 12.3 12.4 0.011 15.6 4.3 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family CTU2 PF10288.9 CDJ59153.1 - 8.2 6.7 6.4 17 5.7 4.6 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 ATP-grasp_2 PF08442.10 CDJ59154.1 - 1.8e-11 44.0 16.5 0.0001 22.0 0.2 3.7 2 1 2 4 4 4 3 ATP-grasp domain Ligase_CoA PF00549.19 CDJ59154.1 - 6.2e-08 32.6 1.1 3.3e-05 23.8 0.1 3.8 4 0 0 4 4 4 2 CoA-ligase ATP-grasp_5 PF13549.6 CDJ59154.1 - 0.0029 17.1 0.2 0.0029 17.1 0.2 1.9 2 0 0 2 2 2 1 ATP-grasp domain DUF2722 PF10846.8 CDJ59154.1 - 0.0045 16.0 1.7 0.0045 16.0 1.7 4.1 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ59154.1 - 0.061 14.3 0.3 0.061 14.3 0.3 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ59154.1 - 0.73 10.1 0.0 0.73 10.1 0.0 4.2 4 0 0 4 4 4 0 Anti-sigma-K factor rskA EIIBC-GUT_N PF03612.14 CDJ59154.1 - 4.1 7.1 27.9 2.9 7.6 0.2 4.4 4 0 0 4 4 4 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxin-13_N PF04088.13 CDJ59154.1 - 7.8 6.8 20.7 0.61 10.4 0.2 4.1 4 0 0 4 4 4 0 Peroxin 13, N-terminal region Suf PF05843.14 CDJ59155.1 - 0.18 11.8 10.5 0.15 12.0 5.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Peroxin-13_N PF04088.13 CDJ59155.1 - 0.31 11.3 5.8 1.8 8.8 1.9 2.6 3 0 0 3 3 3 0 Peroxin 13, N-terminal region FAM176 PF14851.6 CDJ59155.1 - 0.34 10.6 8.5 0.97 9.1 0.1 2.8 3 0 0 3 3 3 0 FAM176 family HA2 PF04408.23 CDJ59155.1 - 0.37 11.1 10.1 2.4 8.5 1.0 2.6 3 0 0 3 3 3 0 Helicase associated domain (HA2) Med15 PF09606.10 CDJ59155.1 - 1.3 7.6 27.0 1.3 7.6 19.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CDJ59155.1 - 1.3 7.9 36.6 0.12 11.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ59155.1 - 1.4 9.9 19.0 1.2 10.1 7.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SprA-related PF12118.8 CDJ59155.1 - 4.2 6.4 27.2 5.5 6.0 3.9 3.0 3 0 0 3 3 3 0 SprA-related family Spt20 PF12090.8 CDJ59155.1 - 6.7 6.2 41.7 0.39 10.3 24.0 2.4 2 1 0 2 2 2 0 Spt20 family DUF1644 PF07800.12 CDJ59155.1 - 8 6.5 11.8 3.6 7.6 2.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) DUF4175 PF13779.6 CDJ59155.1 - 8.1 4.2 21.1 1.7 6.5 13.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) RRM_1 PF00076.22 CDJ59156.1 - 1.9e-19 69.2 0.6 3.3e-19 68.5 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CDJ59156.1 - 9.3e-12 45.4 3.0 9.3e-12 45.4 3.0 3.2 2 1 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.6 CDJ59156.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ59156.1 - 0.059 13.5 0.1 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Di19_C PF14571.6 CDJ59156.1 - 0.17 12.5 2.2 5.1 7.7 0.2 3.0 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal SNRNP27 PF08648.12 CDJ59157.1 - 9.1e-25 86.5 0.8 9.1e-25 86.5 0.8 2.3 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Pex14_N PF04695.13 CDJ59157.1 - 0.0084 16.8 3.7 0.012 16.3 3.7 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ59157.1 - 0.009 15.7 14.9 0.013 15.1 14.9 1.2 1 0 0 1 1 1 1 Spt20 family Topoisom_I_N PF02919.15 CDJ59157.1 - 0.04 13.4 0.3 0.064 12.8 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Band_3_cyto PF07565.13 CDJ59157.1 - 0.48 10.2 3.3 0.61 9.8 3.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ59157.1 - 0.74 9.7 8.9 0.99 9.3 8.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CDJ59157.1 - 0.9 9.6 5.4 1.1 9.2 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region E_Pc_C PF06752.12 CDJ59157.1 - 2 8.5 17.9 3.1 7.8 17.9 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Raftlin PF15250.6 CDJ59157.1 - 5.8 5.6 11.4 4.3 6.0 10.3 1.3 1 1 0 1 1 1 0 Raftlin Peptidase_S64 PF08192.11 CDJ59157.1 - 8.2 4.8 11.2 9.6 4.6 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 HipN PF18253.1 CDJ59159.1 - 2.8e-15 55.7 0.1 4.9e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 CDJ59159.1 - 9.5e-13 47.4 4.8 1.2e-08 34.4 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ59159.1 - 2.5e-12 45.9 7.7 3.6e-07 29.8 0.8 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ59159.1 - 1.4e-09 38.4 11.5 9.1e-06 26.2 1.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ59159.1 - 2.2e-09 37.3 6.1 1.2e-05 25.3 0.7 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ59159.1 - 5.3e-08 32.4 1.2 9.7e-06 25.2 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 CDJ59159.1 - 1e-05 25.9 4.8 0.00081 20.0 0.9 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ59159.1 - 1.4e-05 25.5 8.8 0.00059 20.3 2.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ59159.1 - 3e-05 24.2 9.7 3e-05 24.2 0.7 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ59159.1 - 3.2e-05 23.8 8.5 0.00016 21.6 0.3 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ59159.1 - 0.00011 22.3 3.1 0.005 17.1 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ59159.1 - 0.066 13.4 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Herpes_UL92 PF03048.14 CDJ59160.1 - 0.12 12.2 0.3 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 UL92 family XK-related PF09815.9 CDJ59160.1 - 0.18 10.8 5.6 0.038 13.0 1.8 1.8 2 0 0 2 2 2 0 XK-related protein PDEase_I PF00233.19 CDJ59161.1 - 4.1e-14 52.9 15.1 4.5e-13 49.5 0.0 2.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase TFIIA PF03153.13 CDJ59161.1 - 2.5e-06 27.8 44.9 3.1e-06 27.5 44.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CDJ59161.1 - 0.00014 21.6 11.7 0.00017 21.3 11.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4486 PF14858.6 CDJ59161.1 - 0.001 17.6 9.4 0.0015 17.1 9.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) DDHD PF02862.17 CDJ59161.1 - 0.0036 17.5 13.2 0.005 17.0 13.2 1.3 1 0 0 1 1 1 1 DDHD domain Endostatin PF06482.11 CDJ59161.1 - 0.0037 16.8 12.4 0.0051 16.3 12.4 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin CAF1 PF04857.20 CDJ59161.1 - 0.011 14.9 7.5 0.013 14.6 7.5 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease PAT1 PF09770.9 CDJ59161.1 - 0.021 13.1 35.5 0.025 12.9 35.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 CDJ59161.1 - 0.024 14.2 23.7 0.029 13.9 23.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR1 PF08505.10 CDJ59161.1 - 0.025 14.9 21.5 0.035 14.4 21.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ59161.1 - 0.056 12.3 17.7 0.077 11.8 17.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4045 PF13254.6 CDJ59161.1 - 0.059 13.0 12.7 0.076 12.6 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HD PF01966.22 CDJ59161.1 - 0.067 13.4 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 HD domain V_ATPase_I PF01496.19 CDJ59161.1 - 0.091 10.7 25.8 0.0052 14.8 20.8 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YjbH PF06082.11 CDJ59161.1 - 0.12 11.2 11.5 0.13 11.0 11.5 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH SLC12 PF03522.15 CDJ59161.1 - 0.14 11.2 21.5 0.2 10.6 21.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ59161.1 - 0.15 9.1 19.7 0.18 8.9 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MFS_2 PF13347.6 CDJ59161.1 - 0.2 10.2 0.1 0.34 9.4 0.1 1.4 1 0 0 1 1 1 0 MFS/sugar transport protein Het-C PF07217.11 CDJ59161.1 - 0.42 9.1 13.2 0.52 8.8 13.2 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Ndc1_Nup PF09531.10 CDJ59161.1 - 0.42 9.2 17.1 0.53 8.9 17.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dapper PF15268.6 CDJ59161.1 - 0.5 9.2 26.5 0.62 8.8 26.5 1.1 1 0 0 1 1 1 0 Dapper FAM60A PF15396.6 CDJ59161.1 - 0.65 10.0 16.9 1.3 9.0 16.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CDJ59161.1 - 0.88 9.6 19.7 0.65 10.0 16.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CemA PF03040.14 CDJ59161.1 - 1.1 9.2 13.0 2.3 8.1 13.0 1.6 1 0 0 1 1 1 0 CemA family Presenilin PF01080.17 CDJ59161.1 - 1.1 7.9 26.8 0.024 13.4 19.7 1.7 2 0 0 2 2 2 0 Presenilin RR_TM4-6 PF06459.12 CDJ59161.1 - 1.3 8.8 21.5 0.2 11.5 17.6 1.5 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 FUSC PF04632.12 CDJ59161.1 - 1.6 7.1 11.1 2.1 6.8 11.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PhosphMutase PF10143.9 CDJ59161.1 - 1.7 8.5 4.2 2.8 7.8 4.2 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Conotoxin PF02950.17 CDJ59161.1 - 1.8 9.6 0.0 1.8 9.6 0.0 3.4 2 1 1 3 3 2 0 Conotoxin AMP-binding PF00501.28 CDJ59161.1 - 2 6.9 8.0 34 2.8 8.4 2.1 2 0 0 2 2 2 0 AMP-binding enzyme DUF4050 PF13259.6 CDJ59161.1 - 3.3 8.0 18.6 5.8 7.2 18.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF2347 PF09804.9 CDJ59161.1 - 3.4 7.2 13.6 5.7 6.4 13.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Auxin_canalis PF05703.11 CDJ59161.1 - 3.7 7.4 7.6 5 7.0 7.6 1.3 1 0 0 1 1 1 0 Auxin canalisation GET2 PF08690.10 CDJ59161.1 - 4.4 6.9 30.0 7.5 6.1 30.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 BPL_N PF09825.9 CDJ59161.1 - 5.6 5.9 14.4 7.7 5.5 14.4 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal LAP1C PF05609.12 CDJ59161.1 - 6 5.9 25.0 8.6 5.3 25.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Band_3_cyto PF07565.13 CDJ59161.1 - 7.6 6.2 23.5 13 5.4 23.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MRP-S27 PF10037.9 CDJ59161.1 - 8.1 5.2 28.3 12 4.6 28.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Senescence_reg PF04520.13 CDJ59161.1 - 9 7.1 13.5 15 6.4 13.5 1.4 1 0 0 1 1 1 0 Senescence regulator MDM10 PF12519.8 CDJ59161.1 - 9 5.0 17.2 14 4.4 17.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF2967 PF11179.8 CDJ59162.1 - 0.00027 19.2 10.8 0.00027 19.2 10.8 6.4 4 1 2 6 6 3 1 Protein of unknown function (DUF2967) TMEM51 PF15345.6 CDJ59162.1 - 0.0021 17.9 4.7 0.0021 17.9 4.7 4.7 5 1 0 5 5 5 1 Transmembrane protein 51 Gaa1 PF04114.14 CDJ59162.1 - 0.0047 16.0 3.3 0.0047 16.0 3.3 2.1 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component DUF4207 PF13904.6 CDJ59162.1 - 0.0059 16.3 11.2 0.0059 16.3 11.2 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4207) Pkinase PF00069.25 CDJ59162.1 - 0.014 14.8 0.2 1.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein kinase domain FliP PF00813.20 CDJ59162.1 - 0.12 12.2 2.5 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 FliP family PEX11 PF05648.14 CDJ59162.1 - 0.16 11.4 7.0 2.6 7.4 2.4 2.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) FHIPEP PF00771.20 CDJ59162.1 - 0.22 9.9 7.9 2.2 6.6 2.4 2.7 2 0 0 2 2 2 0 FHIPEP family Dpy19 PF10034.9 CDJ59162.1 - 0.33 9.1 4.2 3 5.9 0.8 2.2 2 0 0 2 2 2 0 Q-cell neuroblast polarisation LapA_dom PF06305.11 CDJ59162.1 - 1.1 9.1 11.0 8 6.4 0.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2852 PF11014.8 CDJ59162.1 - 9.5 6.4 9.2 0.38 10.9 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) Med3 PF11593.8 CDJ59165.1 - 0.0019 17.4 7.7 0.0019 17.4 7.7 2.2 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DUF913 PF06025.12 CDJ59165.1 - 2 7.3 5.4 2.3 7.1 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 CDJ59165.1 - 4.5 7.1 22.7 0.26 11.1 3.6 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Trm112p PF03966.16 CDJ59166.1 - 7.4e-13 48.9 0.1 1.2e-12 48.2 0.1 1.4 1 1 0 1 1 1 1 Trm112p-like protein zf-UDP PF14569.6 CDJ59166.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger SRAP PF02586.14 CDJ59167.1 - 1e-27 97.1 0.0 1e-27 97.1 0.0 2.9 1 1 0 2 2 2 1 SOS response associated peptidase (SRAP) Ribosomal_60s PF00428.19 CDJ59167.1 - 0.02 15.5 4.3 0.02 15.5 4.3 5.4 2 1 1 3 3 3 0 60s Acidic ribosomal protein Med15 PF09606.10 CDJ59167.1 - 5.5 5.5 55.0 0.04 12.6 46.8 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Membralin PF09746.9 CDJ59167.1 - 8.8 5.2 15.9 41 3.0 13.4 2.2 2 0 0 2 2 2 0 Tumour-associated protein RSN1_TM PF13967.6 CDJ59169.1 - 0.12 12.2 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Acyl-CoA_dh_1 PF00441.24 CDJ59170.1 - 6e-25 88.2 0.3 7.2e-25 87.9 0.3 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CDJ59170.1 - 2.6e-05 24.5 0.1 6.7e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Strep_pep PF14404.6 CDJ59170.1 - 0.042 14.1 0.1 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species Peptidase_C97 PF05903.14 CDJ59171.1 - 1.8e-21 76.5 0.1 2.6e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 CDJ59171.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase SUIM_assoc PF16619.5 CDJ59172.1 - 1.8e-06 27.9 0.1 2.7e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ59172.1 - 0.0007 19.9 8.2 0.00081 19.7 8.2 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4307 PF14155.6 CDJ59172.1 - 0.049 13.5 0.5 0.089 12.6 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) Spt20 PF12090.8 CDJ59172.1 - 0.1 12.2 12.7 0.092 12.3 12.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF5529 PF17669.1 CDJ59172.1 - 0.12 12.4 3.5 0.18 11.8 3.5 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5529) DivIC PF04977.15 CDJ59172.1 - 0.21 11.4 7.5 0.25 11.2 7.5 1.1 1 0 0 1 1 1 0 Septum formation initiator K_channel_TID PF07941.11 CDJ59172.1 - 2 8.9 26.1 3.8 8.0 26.2 1.5 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ndufs5 PF10200.9 CDJ59173.1 - 0.015 15.5 2.0 0.023 14.9 2.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Inhibitor_I71 PF12628.7 CDJ59173.1 - 0.018 14.9 2.5 0.02 14.8 2.5 1.0 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor XTBD PF11952.8 CDJ59173.1 - 0.022 14.5 1.4 0.022 14.5 1.4 1.5 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD CDC45 PF02724.14 CDJ59173.1 - 0.45 8.8 12.6 0.48 8.7 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Folliculin PF11704.8 CDJ59173.1 - 1.4 8.8 4.5 1.4 8.7 4.5 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Eapp_C PF10238.9 CDJ59173.1 - 1.7 8.7 7.6 2.1 8.4 7.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 CDJ59173.1 - 2 8.2 13.1 2.1 8.1 13.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 CDJ59173.1 - 2.3 8.1 16.3 2.4 8.0 16.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 CDJ59173.1 - 2.9 5.9 12.8 3.3 5.7 12.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 CDJ59173.1 - 3.2 7.5 7.0 3.4 7.4 7.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Vfa1 PF08432.10 CDJ59173.1 - 3.3 8.0 16.7 3.4 8.0 16.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 CDJ59173.1 - 3.5 6.5 17.0 3.6 6.5 17.0 1.0 1 0 0 1 1 1 0 Paf1 SspB PF04386.13 CDJ59173.1 - 3.5 7.5 7.7 3.7 7.4 7.7 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Ureide_permease PF07168.11 CDJ59173.1 - 4.3 6.0 5.1 4.7 5.9 5.1 1.0 1 0 0 1 1 1 0 Ureide permease Zip PF02535.22 CDJ59173.1 - 5 6.2 4.0 5.4 6.1 4.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter MAP17 PF15807.5 CDJ59173.1 - 7.5 6.8 11.7 8.4 6.6 11.7 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4746 PF15928.5 CDJ59173.1 - 8.7 5.7 15.7 9.5 5.5 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Beta-Casp PF10996.8 CDJ59174.1 - 1.2e-10 41.6 0.0 1.2e-10 41.6 0.0 2.5 2 1 0 2 2 1 1 Beta-Casp domain CPSF73-100_C PF11718.8 CDJ59174.1 - 2.8e-08 33.6 3.8 2.1e-07 30.7 6.0 4.2 1 1 3 4 4 3 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term SR-25 PF10500.9 CDJ59174.1 - 9.3e-06 25.4 17.9 9.3e-06 25.4 17.9 3.8 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 CDJ59174.1 - 3.1e-05 23.0 22.7 0.012 14.5 8.3 2.3 2 0 0 2 2 2 2 Golgi-body localisation protein domain BUD22 PF09073.10 CDJ59174.1 - 0.00015 21.2 61.1 0.0045 16.4 18.7 3.2 2 1 0 3 3 3 2 BUD22 Mpp10 PF04006.12 CDJ59174.1 - 0.00015 20.4 12.7 0.00015 20.4 12.7 2.3 2 0 0 2 2 2 2 Mpp10 protein CDC45 PF02724.14 CDJ59174.1 - 0.0017 16.7 41.2 0.004 15.5 10.3 2.3 2 0 0 2 2 2 2 CDC45-like protein CCSAP PF15748.5 CDJ59174.1 - 0.0034 17.6 23.0 0.0034 17.6 23.0 3.9 3 1 0 3 3 2 1 Centriole, cilia and spindle-associated DUF4604 PF15377.6 CDJ59174.1 - 0.0037 17.7 7.6 0.0037 17.7 7.6 3.8 3 1 0 3 3 2 1 Domain of unknown function (DUF4604) Nop14 PF04147.12 CDJ59174.1 - 0.39 8.9 59.6 1 7.5 32.2 2.4 2 0 0 2 2 2 0 Nop14-like family TT_ORF1 PF02956.14 CDJ59174.1 - 1.3 7.6 8.6 0.35 9.5 1.5 2.1 2 0 0 2 2 2 0 TT viral orf 1 CNDH2_C PF16858.5 CDJ59174.1 - 2.5 7.9 42.5 1.2 9.0 17.9 3.1 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SID-1_RNA_chan PF13965.6 CDJ59174.1 - 8.1 4.7 16.9 0.63 8.4 4.6 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 CDJ59174.1 - 9.3 5.6 43.9 12 5.3 16.1 2.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Coilin_N PF15862.5 CDJ59175.1 - 0.016 15.0 0.1 0.016 15.0 0.1 3.6 1 1 0 2 2 2 0 Coilin N-terminus Hamartin PF04388.12 CDJ59175.1 - 0.063 11.9 24.1 0.079 11.6 24.1 1.1 1 0 0 1 1 1 0 Hamartin protein HEAT_EZ PF13513.6 CDJ59176.1 - 0.00014 22.3 22.1 0.023 15.2 0.0 7.4 9 0 0 9 9 9 3 HEAT-like repeat RIX1 PF08167.12 CDJ59176.1 - 0.00041 20.1 0.5 0.68 9.7 0.3 3.5 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis HTH_15 PF12324.8 CDJ59176.1 - 0.019 14.9 0.2 9.8 6.2 0.0 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase HEAT PF02985.22 CDJ59176.1 - 0.094 13.0 8.2 0.69 10.3 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat HECT PF00632.25 CDJ59179.1 - 3.4e-37 128.6 0.0 1.1e-36 126.9 0.0 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.6 CDJ59179.1 - 4.8e-08 33.4 0.4 0.019 15.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CDJ59179.1 - 8.4e-08 32.3 0.0 0.013 15.9 0.1 5.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CDJ59179.1 - 2e-07 31.5 0.0 2.4e-06 28.0 0.0 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ59179.1 - 4.1e-05 23.8 0.2 2.1 8.8 0.1 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Spt20 PF12090.8 CDJ59179.1 - 0.0075 15.9 0.1 0.0075 15.9 0.1 11.6 11 1 0 11 11 11 2 Spt20 family Ank_3 PF13606.6 CDJ59179.1 - 0.043 14.4 0.0 68 4.5 0.0 4.7 4 0 0 4 4 4 0 Ankyrin repeat UPF0524 PF15823.5 CDJ59184.1 - 1.3 8.4 5.7 3.5 6.9 0.2 3.2 3 0 0 3 3 3 0 UPF0524 of C3orf70 HHH_9 PF17674.1 CDJ59184.1 - 1.6 9.7 6.2 5.9 7.9 0.1 3.9 3 0 0 3 3 3 0 HHH domain Sec62 PF03839.16 CDJ59184.1 - 4.1 6.8 13.1 24 4.3 8.3 3.1 2 1 0 2 2 2 0 Translocation protein Sec62 Peptidase_M20 PF01546.28 CDJ59185.1 - 8.6e-15 55.0 0.1 1e-06 28.6 0.0 3.6 3 0 0 3 3 3 2 Peptidase family M20/M25/M40 WD40 PF00400.32 CDJ59185.1 - 9.9e-08 32.5 14.2 0.08 13.9 0.7 6.1 5 1 0 5 5 5 3 WD domain, G-beta repeat GATase_6 PF13522.6 CDJ59185.1 - 0.00015 22.0 0.0 0.0009 19.4 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase domain M20_dimer PF07687.14 CDJ59185.1 - 0.00018 21.4 0.0 0.00052 19.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain CKS PF01111.19 CDJ59186.1 - 5.2e-21 74.7 0.0 1.1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Amidase_3 PF01520.18 CDJ59187.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase NAD_binding_8 PF13450.6 CDJ59187.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HTH_35 PF13693.6 CDJ59188.1 - 0.13 12.3 0.1 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding CREPT PF16566.5 CDJ59188.1 - 1.8 8.7 6.7 2.6 8.2 0.8 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour A_deaminase PF00962.22 CDJ59189.1 - 2.1e-12 47.0 0.2 3.1e-12 46.5 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Meis_PKNOX_N PF16493.5 CDJ59189.1 - 0.023 15.0 0.1 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 DnaJ_C PF01556.18 CDJ59191.1 - 7.8e-30 103.9 0.0 9.1e-29 100.5 0.0 1.9 1 1 1 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDJ59191.1 - 1.9e-08 34.6 11.3 4.7e-08 33.3 11.3 1.8 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 CDJ59191.1 - 0.11 12.6 0.1 0.63 10.2 0.1 2.0 1 1 0 1 1 1 0 DnaJ domain Mu-like_Pro PF10123.9 CDJ59191.1 - 0.12 11.9 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein NDK PF00334.19 CDJ59193.1 - 3.7e-52 175.9 0.0 4.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UPF0524 PF15823.5 CDJ59194.1 - 0.93 8.8 3.1 1.6 8.1 3.1 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 SUIM_assoc PF16619.5 CDJ59195.1 - 6.3e-05 23.0 13.6 0.0018 18.3 0.5 2.3 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ59195.1 - 0.026 14.1 16.8 0.032 13.8 1.7 2.1 2 0 0 2 2 2 0 Spt20 family Ldh_1_N PF00056.23 CDJ59196.1 - 2.6e-37 128.1 0.5 3.7e-37 127.5 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ59196.1 - 1.3e-25 90.3 0.0 2.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ59196.1 - 1.5e-06 27.9 1.1 2.6e-05 23.9 0.1 2.5 2 1 0 2 2 2 1 Family 4 glycosyl hydrolase Frataxin_Cyay PF01491.16 CDJ59198.1 - 5.9e-13 48.8 0.0 8.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain FAM104 PF15434.6 CDJ59198.1 - 0.04 14.5 1.2 0.05 14.2 1.2 1.2 1 0 0 1 1 1 0 Family 104 DUF755 PF05501.11 CDJ59198.1 - 0.05 13.9 3.7 0.056 13.7 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) IMUP PF15761.5 CDJ59198.1 - 0.07 13.8 4.1 0.075 13.7 4.1 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDJ59198.1 - 0.18 11.4 5.5 0.19 11.3 5.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 CDJ59198.1 - 2.5 6.4 3.9 3 6.2 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HATPase_c_3 PF13589.6 CDJ59200.1 - 3e-11 43.3 1.1 3e-11 43.3 1.1 2.6 2 2 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDJ59200.1 - 1.1e-08 35.5 4.2 2.7e-08 34.3 4.2 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4518 PF15008.6 CDJ59200.1 - 0.0025 17.0 2.0 0.0025 17.0 2.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4518) RskA PF10099.9 CDJ59200.1 - 0.74 10.1 41.7 12 6.2 10.9 3.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF5529 PF17669.1 CDJ59200.1 - 1.4 9.0 8.8 4.7 7.2 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5529) Presenilin PF01080.17 CDJ59200.1 - 7.3 5.3 21.6 0.18 10.5 4.6 2.1 2 0 0 2 2 2 0 Presenilin Activator_LAG-3 PF11498.8 CDJ59201.1 - 4e-06 26.1 40.7 4e-06 26.1 40.7 4.7 4 1 0 4 4 4 1 Transcriptional activator LAG-3 GHMP_kinases_N PF00288.26 CDJ59201.1 - 0.00012 22.2 0.0 0.00012 22.2 0.0 7.8 6 1 1 7 7 7 1 GHMP kinases N terminal domain RskA PF10099.9 CDJ59201.1 - 0.00017 21.9 1.5 0.00017 21.9 1.5 6.7 2 2 3 5 5 5 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ59201.1 - 0.0067 16.1 6.8 0.0067 16.1 6.8 5.6 4 1 0 5 5 5 4 Spt20 family SR-25 PF10500.9 CDJ59202.1 - 4.6 6.8 94.1 0.81 9.3 1.6 5.7 3 1 2 5 5 5 0 Nuclear RNA-splicing-associated protein Rhodanese PF00581.20 CDJ59203.1 - 0.00018 22.0 1.2 0.00056 20.4 0.2 2.4 2 0 0 2 2 2 1 Rhodanese-like domain AF-4 PF05110.13 CDJ59203.1 - 0.00087 17.5 4.6 0.00087 17.5 4.6 6.8 5 2 0 6 6 6 1 AF-4 proto-oncoprotein AF-4 PF05110.13 CDJ59205.1 - 0.001 17.3 5.3 0.001 17.3 5.3 4.4 4 1 0 5 5 5 1 AF-4 proto-oncoprotein PS_Dcarbxylase PF02666.15 CDJ59206.1 - 3.8e-20 72.3 0.0 5.1e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase DNA_primase_lrg PF04104.14 CDJ59207.1 - 2.8e-44 151.5 0.0 4.1e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit His_Phos_1 PF00300.22 CDJ59208.1 - 3.4e-38 131.3 0.0 8.1e-31 107.2 0.1 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Surface_antigen PF11054.8 CDJ59211.1 - 4.5e-12 46.2 0.0 8.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Calpain_III PF01067.22 CDJ59212.1 - 0.27 11.5 0.2 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Calpain large subunit, domain III Alpha-amyl_C2 PF07821.12 CDJ59213.1 - 0.00045 20.4 0.0 0.00067 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain FliD_N PF02465.18 CDJ59214.1 - 0.43 11.3 0.0 0.43 11.3 0.0 7.9 7 2 1 8 8 8 0 Flagellar hook-associated protein 2 N-terminus DUF4732 PF15876.5 CDJ59215.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) XRN_M PF17846.1 CDJ59216.1 - 4.5e-42 144.5 6.0 5.4e-24 85.0 0.0 2.3 2 0 0 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 CDJ59216.1 - 6.4e-08 32.6 0.0 0.0076 16.3 0.0 3.2 3 0 0 3 3 3 2 Xrn1 SH3-like domain Glutaredoxin PF00462.24 CDJ59218.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin FHA PF00498.26 CDJ59219.1 - 2e-12 47.2 0.0 6.8e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ59219.1 - 0.00066 19.9 0.0 0.28 11.5 0.0 2.3 1 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain MCR PF18509.1 CDJ59219.1 - 0.079 12.5 1.2 0.22 11.1 1.2 1.7 1 0 0 1 1 1 0 Magnetochrome domain Codanin-1_C PF15296.6 CDJ59222.1 - 0.43 10.7 7.5 0.75 9.9 0.6 3.0 3 0 0 3 3 3 0 Codanin-1 C-terminus EF-hand_7 PF13499.6 CDJ59223.1 - 6.4e-16 58.6 0.0 1.1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ59223.1 - 7.6e-15 53.3 0.0 0.0014 18.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDJ59223.1 - 3.1e-13 48.5 0.0 0.017 15.0 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 CDJ59223.1 - 2.6e-09 37.3 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ59223.1 - 1.3e-06 28.2 0.1 1.2 9.0 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDJ59223.1 - 3.3e-06 26.3 0.1 0.14 11.7 0.0 3.6 4 0 0 4 4 4 2 EF hand DUF3911 PF13050.6 CDJ59223.1 - 0.018 15.1 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) SPARC_Ca_bdg PF10591.9 CDJ59223.1 - 0.029 14.7 0.0 4.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region VIT1 PF01988.19 CDJ59224.1 - 1.1e-56 192.1 0.5 1.6e-56 191.6 0.5 1.2 1 0 0 1 1 1 1 VIT family SH3-WW_linker PF16618.5 CDJ59224.1 - 0.014 15.9 0.1 0.021 15.3 0.1 1.1 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 DUF1700 PF08006.11 CDJ59224.1 - 5.3 6.5 6.0 50 3.4 6.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) SNF PF00209.18 CDJ59225.1 - 6.2e-13 48.3 30.9 1.5e-11 43.7 25.2 3.0 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family RskA PF10099.9 CDJ59226.1 - 0.0019 18.5 11.0 0.0019 18.5 11.0 8.7 3 2 3 6 6 6 1 Anti-sigma-K factor rskA GFP PF01353.22 CDJ59229.1 - 3.8e-23 82.1 0.1 4.4e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Green fluorescent protein Beta-lactamase2 PF13354.6 CDJ59230.1 - 4.2e-39 134.3 0.0 5.2e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 CDJ59230.1 - 9.8e-30 103.9 0.0 1.8e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 CDJ59230.1 - 2.5e-06 27.1 0.0 6.4e-06 25.8 0.0 1.5 1 1 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase GFP PF01353.22 CDJ59231.1 - 1.3e-97 325.6 0.7 1.5e-97 325.4 0.7 1.0 1 0 0 1 1 1 1 Green fluorescent protein Peptidase_S8 PF00082.22 CDJ59234.1 - 1e-46 159.6 0.3 1.5e-46 159.0 0.3 1.2 1 0 0 1 1 1 1 Subtilase family CPSase_L_D2 PF02786.17 CDJ59235.1 - 7.1e-25 87.8 0.2 1.1e-24 87.2 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 CDJ59235.1 - 5.2e-08 32.7 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CDJ59235.1 - 1.3e-06 28.1 0.1 2.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CDJ59235.1 - 3e-06 26.9 0.4 5.2e-06 26.1 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 CDJ59235.1 - 4.9e-06 26.7 0.1 1.4e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain ATP-grasp_3 PF02655.14 CDJ59235.1 - 0.0056 16.7 0.2 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain SPAR_C PF11881.8 CDJ59236.1 - 0.019 14.9 4.0 0.025 14.5 4.0 1.2 1 0 0 1 1 1 0 C-terminal domain of SPAR protein MerR-DNA-bind PF09278.11 CDJ59236.1 - 0.056 14.0 3.3 0.056 14.0 3.3 2.0 1 1 1 2 2 2 0 MerR, DNA binding Acyl-CoA_dh_2 PF08028.11 CDJ59236.1 - 0.13 12.5 8.2 0.28 11.5 8.2 1.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Pex26 PF07163.12 CDJ59236.1 - 0.25 10.6 5.9 0.28 10.5 5.9 1.0 1 0 0 1 1 1 0 Pex26 protein Gastrin PF00918.17 CDJ59236.1 - 0.35 11.8 7.6 0.39 11.7 7.6 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family GCN5L1 PF06320.13 CDJ59236.1 - 0.55 10.4 15.1 0.69 10.1 15.1 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Spt20 PF12090.8 CDJ59236.1 - 0.71 9.4 16.7 0.77 9.3 16.7 1.1 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 CDJ59236.1 - 1.2 8.8 10.8 1.4 8.5 10.8 1.1 1 0 0 1 1 1 0 FAM176 family DUF3450 PF11932.8 CDJ59236.1 - 1.4 8.2 18.8 1.5 8.1 18.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Androgen_recep PF02166.16 CDJ59236.1 - 2 7.2 10.0 2.1 7.1 10.0 1.1 1 0 0 1 1 1 0 Androgen receptor Roughex PF06020.11 CDJ59236.1 - 6 5.9 11.5 6.3 5.8 11.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein FUSC-like PF12805.7 CDJ59236.1 - 8.4 5.4 11.5 0.13 11.3 2.6 1.8 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS HemX PF04375.14 CDJ59236.1 - 9 5.5 19.5 9.7 5.4 19.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Neur_chan_memb PF02932.16 CDJ59236.1 - 9.1 6.3 7.8 9.6 6.2 7.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 CDJ59237.1 - 1.9e-21 75.9 10.6 0.0043 17.9 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ59237.1 - 6.6e-07 29.5 1.0 0.67 10.3 0.1 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Dapper PF15268.6 CDJ59237.1 - 0.43 9.4 25.7 0.63 8.8 25.7 1.2 1 0 0 1 1 1 0 Dapper DUF966 PF06136.13 CDJ59237.1 - 0.74 9.5 13.4 1.3 8.7 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) WTX PF09422.10 CDJ59237.1 - 1.7 7.6 18.7 0.54 9.3 15.1 1.7 2 0 0 2 2 2 0 WTX protein GREB1 PF15782.5 CDJ59237.1 - 3.8 4.5 22.4 5.2 4.0 22.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PCI PF01399.27 CDJ59240.1 - 1.2e-08 35.4 0.0 7.9e-08 32.8 0.0 2.3 3 0 0 3 3 3 1 PCI domain DUF3896 PF13035.6 CDJ59240.1 - 0.073 13.2 1.2 0.3 11.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Secretin_N_2 PF07655.13 CDJ59240.1 - 1.2 9.7 10.7 2.2 8.9 10.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain AvrB_AvrC PF05394.11 CDJ59241.1 - 0.049 12.8 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein UxaC PF02614.14 CDJ59241.1 - 0.2 10.5 0.0 0.43 9.4 0.0 1.5 2 0 0 2 2 2 0 Glucuronate isomerase Parathyroid PF01279.17 CDJ59245.1 - 0.03 15.0 2.6 0.03 15.0 2.6 2.9 2 1 0 2 2 2 0 Parathyroid hormone family PIG-S PF10510.9 CDJ59246.1 - 1.2e-07 31.0 0.0 4.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Notch PF00066.17 CDJ59246.1 - 0.17 12.4 1.8 0.39 11.2 1.8 1.5 1 0 0 1 1 1 0 LNR domain PBP1_TM PF14812.6 CDJ59248.1 - 0.17 12.3 0.1 0.17 12.3 0.1 5.4 3 2 2 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SepSecS PF05889.13 CDJ59249.1 - 1.9e-23 82.8 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SAD_SRA PF02182.17 CDJ59250.1 - 0.0043 16.8 0.0 0.0043 16.8 0.0 2.3 3 0 0 3 3 3 1 SAD/SRA domain SelK_SelG PF10961.8 CDJ59253.1 - 2 9.1 6.7 2.9 8.6 6.7 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF2201_N PF13203.6 CDJ59253.1 - 5.9 6.4 7.9 7.3 6.1 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain WD40 PF00400.32 CDJ59254.1 - 4.4e-17 62.1 13.7 3.8e-05 24.4 1.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ59254.1 - 2.9e-06 27.5 0.0 0.37 11.1 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ59254.1 - 0.0077 15.2 0.2 0.34 9.8 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrolase_4 PF12146.8 CDJ59255.1 - 2.2e-10 40.2 0.5 1.1e-06 28.1 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDJ59255.1 - 1.1e-06 28.3 0.0 1.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDJ59255.1 - 2.9e-06 28.0 0.7 6.6e-06 26.9 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ59255.1 - 2.4e-05 24.1 0.1 0.0053 16.4 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ59255.1 - 0.0026 17.6 0.1 0.04 13.7 0.1 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDJ59255.1 - 0.0077 15.9 0.0 0.039 13.6 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Ntox34 PF15606.6 CDJ59255.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 34 Pkinase PF00069.25 CDJ59256.1 - 3.5e-24 85.6 0.0 1.2e-11 44.5 0.0 4.0 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59256.1 - 1.6e-08 34.1 0.0 0.00062 19.1 0.0 4.4 4 0 0 4 4 4 2 Protein tyrosine kinase EcKinase PF02958.20 CDJ59256.1 - 0.45 9.8 0.0 0.45 9.8 0.0 2.6 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 CDJ59256.1 - 1.2 7.8 0.0 1.2 7.8 0.0 3.1 3 1 0 3 3 3 0 Fungal protein kinase DHHC PF01529.20 CDJ59257.1 - 1.1e-38 132.4 12.8 1.5e-37 128.6 5.3 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase TMEM239 PF15841.5 CDJ59257.1 - 0.0044 16.9 5.3 2.1 8.2 3.7 3.0 3 0 0 3 3 3 2 Transmembrane protein 239 family SUR7 PF06687.12 CDJ59257.1 - 0.026 14.2 0.1 0.026 14.2 0.1 2.2 2 1 0 2 2 2 0 SUR7/PalI family Yip1 PF04893.17 CDJ59257.1 - 1.1 9.0 10.5 4.2 7.1 1.3 2.2 2 0 0 2 2 2 0 Yip1 domain Colicin_V PF02674.16 CDJ59257.1 - 4.1 7.4 16.2 0.79 9.7 4.1 2.5 2 1 0 2 2 2 0 Colicin V production protein Tetraspanin PF00335.20 CDJ59257.1 - 5.9 6.5 13.7 0.85 9.3 1.5 2.7 2 1 0 2 2 2 0 Tetraspanin family START PF01852.19 CDJ59258.1 - 9.8e-10 38.2 0.0 1.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 START domain TP_methylase PF00590.20 CDJ59260.1 - 1.7e-23 83.7 0.1 3.5e-23 82.7 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UQ_con PF00179.26 CDJ59261.1 - 1.4e-47 160.9 0.1 1.6e-47 160.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ59261.1 - 0.00027 20.6 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ59261.1 - 0.0096 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Rhomboid PF01694.22 CDJ59262.1 - 4.7e-30 104.6 10.7 6.2e-30 104.2 10.7 1.2 1 0 0 1 1 1 1 Rhomboid family APG5 PF04106.12 CDJ59263.1 - 3e-45 154.6 0.0 4.6e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 Ribosomal_L18 PF17135.4 CDJ59264.1 - 3.3e-18 65.7 0.0 4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDJ59264.1 - 0.001 19.7 0.1 0.0071 17.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CS PF04969.16 CDJ59265.1 - 2.3e-12 47.8 0.0 2.8e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 CS domain Ribosomal_L28e PF01778.17 CDJ59266.1 - 1.3e-30 106.5 1.6 1.3e-30 106.5 1.6 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CDJ59266.1 - 2.5e-18 66.5 6.5 6.1e-18 65.3 6.5 1.7 1 0 0 1 1 1 1 Mak16 protein C-terminal region RepB-RCR_reg PF10723.9 CDJ59266.1 - 0.11 12.4 3.2 0.11 12.4 0.6 2.2 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF630 PF04783.12 CDJ59266.1 - 1.6 9.0 3.8 20 5.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Spt20 PF12090.8 CDJ59267.1 - 0.015 14.9 5.5 0.015 14.9 5.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ59267.1 - 0.018 14.0 1.6 0.016 14.2 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FTZ PF03867.14 CDJ59267.1 - 0.18 11.3 1.3 0.19 11.3 1.3 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SUIM_assoc PF16619.5 CDJ59267.1 - 1.3 9.2 16.0 2.5 8.2 16.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 CDJ59267.1 - 4.4 6.0 7.8 5.1 5.8 7.8 1.1 1 0 0 1 1 1 0 Androgen receptor DUF1712 PF08217.11 CDJ59268.1 - 0.011 14.3 0.1 0.014 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Zein-binding PF04576.15 CDJ59268.1 - 0.016 15.5 1.6 0.15 12.3 0.1 2.7 2 0 0 2 2 2 0 Zein-binding Peptidase_M16 PF00675.20 CDJ59268.1 - 1.7 8.6 4.3 0.53 10.2 0.1 2.2 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) FAM76 PF16046.5 CDJ59269.1 - 0.048 13.0 16.0 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 FAM76 protein TMEM51 PF15345.6 CDJ59269.1 - 0.064 13.1 0.1 0.064 13.1 0.1 3.3 2 1 1 3 3 2 0 Transmembrane protein 51 FAM176 PF14851.6 CDJ59269.1 - 0.086 12.5 0.2 0.086 12.5 0.2 3.2 2 1 0 2 2 1 0 FAM176 family Zip PF02535.22 CDJ59269.1 - 0.24 10.6 8.2 0.54 9.4 4.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ59269.1 - 0.42 9.6 9.2 5.6 5.9 5.6 2.2 2 0 0 2 2 2 0 CLN3 protein V_ATPase_I PF01496.19 CDJ59269.1 - 0.91 7.4 16.6 1.3 6.8 10.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family cwf18 PF08315.12 CDJ59269.1 - 2.1 9.0 23.9 5.9 7.6 11.3 2.4 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor SARAF PF06682.12 CDJ59269.1 - 2.3 7.8 18.7 3.5 7.2 0.0 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis RPN2_C PF18004.1 CDJ59269.1 - 2.4 8.0 20.4 0.3 11.0 2.4 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain SID-1_RNA_chan PF13965.6 CDJ59269.1 - 2.8 6.3 5.4 7.8 4.8 0.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4050 PF13259.6 CDJ59269.1 - 3 8.1 11.5 11 6.3 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) TRAP_alpha PF03896.16 CDJ59269.1 - 3 7.0 8.9 3.1 6.9 0.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF5427 PF10310.9 CDJ59269.1 - 3.1 6.7 26.6 0.038 13.0 13.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Serinc PF03348.15 CDJ59269.1 - 3.1 6.6 7.2 7.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) PIEZO PF15917.5 CDJ59269.1 - 4.5 6.7 23.0 3.2 7.2 2.0 2.2 2 0 0 2 2 2 0 Piezo NicO PF03824.16 CDJ59269.1 - 6.1 6.1 6.8 1.4e+02 1.7 7.2 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein TPR_1 PF00515.28 CDJ59270.1 - 1.6e-22 78.3 1.8 1.9e-07 30.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ59270.1 - 1.8e-20 71.3 1.0 6.9e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ59270.1 - 1e-18 65.9 1.2 3.1e-05 23.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ59270.1 - 1.4e-16 59.9 1.0 6.5e-08 32.1 0.0 3.5 2 1 2 4 4 3 3 TPR repeat TPR_14 PF13428.6 CDJ59270.1 - 1.3e-11 44.3 0.6 0.00068 20.3 0.1 3.8 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ59270.1 - 7.3e-10 38.5 0.2 0.012 16.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ59270.1 - 1.1e-09 38.7 0.1 0.00023 21.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ59270.1 - 5.8e-09 36.3 2.4 0.0015 19.0 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ59270.1 - 2.2e-08 34.1 0.1 0.0014 18.7 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ59270.1 - 6.9e-08 32.7 0.7 0.0007 19.8 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ59270.1 - 4.1e-05 23.3 0.1 0.2 11.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 CDJ59270.1 - 0.00012 21.2 0.4 0.00016 20.8 0.4 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 CDJ59270.1 - 0.00012 21.8 0.1 0.78 9.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ59270.1 - 0.0013 18.8 1.2 0.81 9.8 0.0 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 CDJ59270.1 - 0.0023 17.4 0.1 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 SHNi-TPR STI1 PF17830.1 CDJ59270.1 - 0.0031 17.4 0.5 0.011 15.6 0.3 2.1 1 1 0 1 1 1 1 STI1 domain YIEGIA PF14045.6 CDJ59270.1 - 0.0078 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 YIEGIA protein MAS20 PF02064.15 CDJ59270.1 - 0.011 15.9 0.3 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor HemY_N PF07219.13 CDJ59270.1 - 0.012 15.8 3.4 0.24 11.6 0.1 2.6 1 1 0 2 2 2 0 HemY protein N-terminus TPR_20 PF14561.6 CDJ59270.1 - 0.015 15.6 1.3 0.89 9.9 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDJ59270.1 - 0.05 13.7 0.6 0.32 11.1 0.4 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 CDJ59270.1 - 0.069 13.6 1.8 1.4 9.3 1.1 2.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain ChAPs PF09295.10 CDJ59270.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CDJ59270.1 - 0.32 11.7 4.2 43 5.0 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40_alt PF14077.6 CDJ59273.1 - 0.09 12.7 5.8 16 5.5 0.1 3.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif Fez1 PF06818.15 CDJ59273.1 - 0.26 11.7 60.9 0.06 13.8 3.7 3.4 2 1 0 3 3 3 0 Fez1 SID-1_RNA_chan PF13965.6 CDJ59274.1 - 0.47 8.8 3.3 0.18 10.2 0.3 1.8 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 RAP1 PF07218.11 CDJ59275.1 - 4.1 5.5 8.0 7 4.8 8.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IMCp PF12314.8 CDJ59276.1 - 8.2e-07 29.2 7.7 1.2e-06 28.7 7.7 1.2 1 0 0 1 1 1 1 Inner membrane complex protein CPSase_L_D3 PF02787.19 CDJ59280.1 - 4.7e-37 127.0 0.0 7.7e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain NBD_C PF17042.5 CDJ59280.1 - 0.065 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain CLP_protease PF00574.23 CDJ59281.1 - 3.2e-07 30.4 1.7 0.0093 15.9 0.1 2.7 3 0 0 3 3 3 2 Clp protease DUF4446 PF14584.6 CDJ59281.1 - 0.48 10.4 4.3 1.2 9.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HemX PF04375.14 CDJ59281.1 - 0.85 8.8 38.6 0.1 11.9 5.4 3.1 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Chorion_2 PF03964.15 CDJ59282.1 - 0.0072 17.1 1.9 0.0072 17.1 1.9 3.1 2 1 1 3 3 3 1 Chorion family 2 Nop14 PF04147.12 CDJ59282.1 - 0.054 11.7 43.6 0.082 11.1 43.6 1.4 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 CDJ59282.1 - 0.19 11.7 52.2 0.085 12.9 49.7 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) SURF6 PF04935.12 CDJ59282.1 - 0.57 9.9 42.5 0.031 14.1 34.0 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 SR-25 PF10500.9 CDJ59282.1 - 3.6 7.1 55.4 16 5.0 39.9 2.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 CDJ59282.1 - 7.4 6.6 42.6 5.2 7.1 20.6 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RNA_polI_A34 PF08208.11 CDJ59283.1 - 1 9.4 46.1 0.55 10.3 27.8 2.7 1 1 1 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF262 PF03235.14 CDJ59283.1 - 3.3 7.8 11.2 5.9 7.0 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF262 Pkinase PF00069.25 CDJ59284.1 - 2.6e-09 36.9 0.0 2.6e-09 36.9 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain zf-UBP_var PF17807.1 CDJ59286.1 - 0.19 11.5 0.1 0.65 9.8 0.1 1.9 1 0 0 1 1 1 0 Variant UBP zinc finger DUF5583 PF17821.1 CDJ59287.1 - 0.062 13.3 0.2 0.073 13.0 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5583) T2SSppdC PF12528.8 CDJ59288.1 - 0.054 14.3 0.9 0.054 14.3 0.9 2.1 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C G2BR PF18442.1 CDJ59288.1 - 0.2 11.3 5.7 0.55 9.9 5.7 1.8 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DUF547 PF04784.14 CDJ59290.1 - 1.6e-19 70.1 3.1 2.9e-19 69.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF547 PAT1 PF09770.9 CDJ59290.1 - 1.2 7.3 40.6 2.2 6.4 40.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ59290.1 - 3.9 5.7 27.4 5.8 5.1 27.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CDJ59290.1 - 9.7 5.1 28.2 18 4.2 28.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Ras PF00071.22 CDJ59291.1 - 4.6e-12 45.8 0.0 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDJ59291.1 - 0.00094 19.4 0.0 0.075 13.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ59291.1 - 0.063 12.7 0.0 7.1 6.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 CDJ59291.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CDJ59291.1 - 0.19 11.8 0.0 0.49 10.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CDJ59291.1 - 0.19 12.2 0.1 0.4 11.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter K_channel_TID PF07941.11 CDJ59292.1 - 0.029 14.8 2.5 0.029 14.8 2.5 4.8 5 1 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 CDJ59292.1 - 5.9 7.1 17.2 0.86 9.9 8.5 3.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA UTP15_C PF09384.10 CDJ59293.1 - 2.4e-15 56.5 0.5 5e-15 55.5 0.5 1.6 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CDJ59293.1 - 7.1e-09 36.2 2.3 0.00091 20.0 0.1 5.8 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ59293.1 - 5.2e-05 23.5 0.0 0.13 12.6 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 CDJ59293.1 - 0.88 9.5 13.3 4.1 7.3 7.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit E_Pc_C PF06752.12 CDJ59293.1 - 2.4 8.2 16.5 3.5 7.7 4.8 2.8 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Spt20 PF12090.8 CDJ59293.1 - 3.9 7.0 16.1 0.87 9.1 0.2 2.4 2 0 0 2 2 2 0 Spt20 family Diacid_rec PF05651.13 CDJ59293.1 - 5.4 6.7 6.6 0.29 10.8 0.2 1.9 2 0 0 2 2 2 0 Putative sugar diacid recognition SID-1_RNA_chan PF13965.6 CDJ59294.1 - 0.0036 15.8 2.1 0.0052 15.3 2.1 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 TFIIA PF03153.13 CDJ59294.1 - 0.0055 16.8 37.5 0.0071 16.4 37.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ59294.1 - 0.032 14.2 21.9 0.036 14.1 21.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2828 PF11443.8 CDJ59294.1 - 0.054 11.6 11.9 0.069 11.2 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) V_ATPase_I PF01496.19 CDJ59294.1 - 0.16 9.9 19.9 0.19 9.6 19.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 CDJ59294.1 - 0.21 10.3 20.0 0.25 10.1 20.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 CDJ59294.1 - 0.41 10.6 17.5 0.54 10.2 17.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDRGK PF09756.9 CDJ59294.1 - 0.57 9.8 31.5 0.86 9.2 31.5 1.4 1 0 0 1 1 1 0 DDRGK domain RP-C_C PF11800.8 CDJ59294.1 - 0.59 10.2 19.9 0.77 9.8 19.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4746 PF15928.5 CDJ59294.1 - 0.61 9.5 14.9 0.75 9.2 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CDJ59294.1 - 0.64 8.7 27.9 1 8.1 27.9 1.3 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CDJ59294.1 - 0.82 7.9 32.7 0.96 7.6 32.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Velvet PF11754.8 CDJ59294.1 - 0.87 9.5 16.8 1.1 9.2 16.8 1.2 1 0 0 1 1 1 0 Velvet factor XRN_M PF17846.1 CDJ59294.1 - 0.92 8.4 17.5 1.2 8.1 17.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 CDJ59294.1 - 1.3 8.3 25.0 1.5 8.1 25.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 CDJ59294.1 - 1.3 9.3 25.3 1.9 8.8 25.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Endostatin PF06482.11 CDJ59294.1 - 1.3 8.4 18.1 1.7 8.1 18.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 CDJ59294.1 - 1.4 7.9 23.9 1.7 7.6 23.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CDJ59294.1 - 1.4 8.6 24.2 1.8 8.3 24.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 CDJ59294.1 - 1.7 7.5 23.2 2.3 7.1 23.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 CDJ59294.1 - 1.8 6.6 22.1 2.1 6.4 22.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 CDJ59294.1 - 1.9 8.2 17.4 2.5 7.9 17.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GREB1 PF15782.5 CDJ59294.1 - 2 5.4 16.8 2.1 5.4 16.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 CDJ59294.1 - 2.1 8.3 22.7 2.6 8.1 22.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GAGA_bind PF06217.12 CDJ59294.1 - 2.5 8.3 16.8 3 8.0 16.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family HCO3_cotransp PF00955.21 CDJ59294.1 - 2.7 6.7 4.7 3.3 6.4 4.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family Lin-8 PF03353.15 CDJ59294.1 - 3.6 7.1 28.6 4.6 6.7 28.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ59294.1 - 3.7 6.3 18.2 4.5 6.0 18.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 CDJ59294.1 - 4 6.2 9.6 4.2 6.2 9.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF913 PF06025.12 CDJ59294.1 - 4.1 6.3 12.5 5.8 5.8 12.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VIR_N PF15912.5 CDJ59294.1 - 4.9 6.7 18.0 6 6.4 18.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 CDJ59294.1 - 5.4 7.0 19.3 7.3 6.6 19.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 CDJ59294.1 - 6.8 5.3 19.2 7.9 5.1 19.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peroxin-3 PF04882.12 CDJ59294.1 - 7.9 5.4 27.0 9.8 5.0 27.0 1.1 1 0 0 1 1 1 0 Peroxin-3 Zip PF02535.22 CDJ59294.1 - 8 5.6 15.6 11 5.2 15.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 CDJ59295.1 - 1.4e-09 38.7 1.4 2.9e-09 37.7 0.2 1.9 2 0 0 2 2 2 1 Ctr copper transporter family Glyco_tran_28_C PF04101.16 CDJ59297.1 - 2.4e-16 60.1 0.0 9.9e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain DUF2335 PF10097.9 CDJ59298.1 - 0.054 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) SNF2_N PF00176.23 CDJ59300.1 - 7.2e-16 57.8 0.0 4.6e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.19 CDJ59300.1 - 1.4e-08 34.4 4.2 3.3e-08 33.2 4.2 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Helicase_C PF00271.31 CDJ59300.1 - 0.00053 20.3 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ59300.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ59300.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Cyclin PF08613.11 CDJ59302.1 - 2.2e-29 102.9 0.1 2.2e-29 102.9 0.1 2.6 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 CDJ59302.1 - 1e-06 28.5 0.0 1e-06 28.5 0.0 3.7 3 1 1 4 4 4 1 Cyclin, N-terminal domain CRF1 PF10380.9 CDJ59302.1 - 3 8.2 0.0 3 8.2 0.0 3.3 3 1 0 4 4 4 0 Transcription factor CRF1 DUF4179 PF13786.6 CDJ59304.1 - 0.00096 19.6 3.9 0.91 10.0 0.0 3.6 2 2 0 2 2 2 2 Domain of unknown function (DUF4179) V-ATPase_G PF03179.15 CDJ59306.1 - 7.4e-06 26.5 16.6 1.2e-05 25.8 16.6 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit FAM76 PF16046.5 CDJ59306.1 - 0.068 12.5 0.3 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein MOZART1 PF12554.8 CDJ59307.1 - 2.4e-18 65.6 0.4 3.8e-18 65.0 0.4 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated ArgoL1 PF08699.10 CDJ59308.1 - 0.61 9.8 6.5 29 4.4 0.1 3.7 4 0 0 4 4 4 0 Argonaute linker 1 domain PRP38_assoc PF12871.7 CDJ59308.1 - 2.6 8.7 6.9 83 3.9 0.1 3.2 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term B9-C2 PF07162.11 CDJ59309.1 - 0.00023 21.4 0.0 0.00023 21.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ribosomal_60s PF00428.19 CDJ59310.1 - 4.9 7.8 40.9 0.39 11.3 13.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Kinase-like PF14531.6 CDJ59311.1 - 1.9e-08 34.0 0.0 3.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Chromo PF00385.24 CDJ59312.1 - 5.7e-06 26.1 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Utp14 PF04615.13 CDJ59313.1 - 4.8e-68 230.5 94.8 1.6e-37 129.5 46.8 2.5 1 1 1 2 2 2 2 Utp14 protein Fip1 PF05182.13 CDJ59314.1 - 0.00096 18.6 1.5 0.0023 17.4 1.5 1.6 1 0 0 1 1 1 1 Fip1 motif ALMT PF11744.8 CDJ59314.1 - 0.31 9.8 4.8 0.37 9.6 4.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 CDJ59314.1 - 0.53 8.5 20.6 0.6 8.3 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ59314.1 - 1.5 8.8 5.3 2.3 8.2 5.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CDJ59314.1 - 3 7.0 5.9 3.8 6.6 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GCP_C_terminal PF04130.13 CDJ59316.1 - 4.5e-14 52.6 0.0 8.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDJ59316.1 - 1.1e-09 38.4 0.0 3.4e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal YqzE PF14038.6 CDJ59316.1 - 1.7 8.7 3.6 10 6.2 0.2 2.7 2 0 0 2 2 2 0 YqzE-like protein RskA PF10099.9 CDJ59317.1 - 0.00016 22.0 30.7 0.028 14.7 14.2 2.4 2 0 0 2 2 2 2 Anti-sigma-K factor rskA AstE_AspA PF04952.14 CDJ59317.1 - 0.0025 16.9 2.0 0.0039 16.3 2.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Dehydrin PF00257.19 CDJ59317.1 - 0.0072 16.9 2.1 0.0072 16.9 2.1 3.0 2 1 0 2 2 2 1 Dehydrin TERB2 PF15101.6 CDJ59317.1 - 0.11 12.6 11.6 0.56 10.2 0.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF2298 PF10060.9 CDJ59317.1 - 0.8 8.4 9.2 0.065 11.9 2.1 2.0 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) SR-25 PF10500.9 CDJ59317.1 - 2.5 7.7 14.4 0.065 12.8 3.1 2.2 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ59317.1 - 2.6 8.0 38.3 4.1 7.3 38.2 1.4 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ59317.1 - 2.9 6.8 34.2 0.19 10.7 16.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PAT1 PF09770.9 CDJ59317.1 - 6.4 4.9 20.4 7.8 4.6 20.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RP-C_C PF11800.8 CDJ59318.1 - 0.018 15.2 5.4 0.022 14.9 5.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region TFIIA PF03153.13 CDJ59318.1 - 0.079 13.0 27.2 0.083 12.9 27.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BBP1_N PF15271.6 CDJ59318.1 - 0.14 13.0 5.5 0.17 12.7 5.5 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein TERB2 PF15101.6 CDJ59318.1 - 0.63 10.1 10.6 0.8 9.7 10.6 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MMR1 PF08505.10 CDJ59318.1 - 0.74 10.1 10.8 0.84 9.9 10.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pex14_N PF04695.13 CDJ59318.1 - 1.3 9.7 15.8 1.7 9.3 15.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 CDJ59318.1 - 1.4 7.1 17.8 1.5 7.0 17.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2464 PF10240.9 CDJ59318.1 - 1.8 8.1 7.5 2.2 7.8 7.5 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 EMC3_TMCO1 PF01956.16 CDJ59318.1 - 3.3 7.4 7.3 3.5 7.3 7.3 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4457 PF14652.6 CDJ59318.1 - 4.2 6.5 6.6 5.2 6.2 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) EIIBC-GUT_N PF03612.14 CDJ59318.1 - 4.8 6.9 6.7 6 6.6 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2722 PF10846.8 CDJ59318.1 - 7.3 5.4 20.4 8.5 5.2 20.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Totivirus_coat PF05518.11 CDJ59319.1 - 4.6 5.2 15.2 5.7 4.8 15.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein FXMRP1_C_core PF12235.8 CDJ59319.1 - 9 6.9 23.9 6.2 7.5 7.5 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Vps35 PF03635.17 CDJ59320.1 - 1.1e-81 275.4 0.2 6.6e-81 272.9 0.1 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 35 Xpo1 PF08389.12 CDJ59320.1 - 0.0078 16.3 0.3 0.042 13.9 0.3 2.4 1 1 0 1 1 1 1 Exportin 1-like protein Npa1 PF11707.8 CDJ59320.1 - 0.02 14.3 0.6 0.038 13.4 0.6 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Amidase_2 PF01510.25 CDJ59320.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase HXXSHH PF07586.11 CDJ59322.1 - 0.026 14.1 0.5 0.043 13.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Pox_A_type_inc PF04508.12 CDJ59322.1 - 0.35 10.8 2.0 0.78 9.7 1.5 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Jnk-SapK_ap_N PF09744.9 CDJ59322.1 - 0.54 10.5 16.8 1 9.6 16.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 CDJ59322.1 - 0.58 9.7 8.4 0.96 9.0 8.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CDJ59322.1 - 0.76 9.8 7.8 4.3 7.4 3.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1269 PF06897.12 CDJ59322.1 - 2.3 8.5 6.1 7.4 6.9 5.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Spc7 PF08317.11 CDJ59322.1 - 2.7 6.8 19.9 3.7 6.3 19.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 CDJ59322.1 - 2.8 6.4 13.4 3.8 6.0 13.4 1.1 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 CDJ59322.1 - 3.7 7.8 22.0 7.4 6.8 10.6 2.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CtIP_N PF10482.9 CDJ59322.1 - 5.9 7.0 14.4 18 5.4 14.4 1.8 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Seryl_tRNA_N PF02403.22 CDJ59322.1 - 6.5 7.0 19.4 2.3 8.5 11.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.6 CDJ59322.1 - 6.9 5.2 11.0 10 4.7 11.0 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDJ59323.1 - 0.00079 18.7 0.1 0.001 18.3 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CDJ59323.1 - 0.0014 19.0 0.3 0.0014 19.0 0.3 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDJ59323.1 - 0.0015 18.3 0.2 0.0015 18.3 0.2 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 CDJ59323.1 - 0.0022 17.3 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 CDJ59323.1 - 0.0023 17.7 0.4 0.003 17.4 0.4 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 CDJ59323.1 - 0.0026 17.5 0.0 0.0074 16.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CDJ59323.1 - 0.0068 16.6 2.0 0.0082 16.3 0.3 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CDJ59323.1 - 0.0079 16.1 0.3 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CDJ59323.1 - 0.0097 16.5 0.5 0.015 15.9 0.5 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDJ59323.1 - 0.01 15.4 0.3 0.015 14.9 0.3 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 CDJ59323.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 CDJ59323.1 - 0.015 15.6 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ59323.1 - 0.015 15.8 3.2 0.023 15.2 0.6 1.9 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.6 CDJ59323.1 - 0.019 15.5 0.1 0.033 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain RskA PF10099.9 CDJ59323.1 - 0.033 14.5 13.1 0.041 14.2 13.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TsaE PF02367.17 CDJ59323.1 - 0.046 13.7 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CDJ59323.1 - 0.07 12.7 0.2 0.07 12.7 0.2 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CDJ59323.1 - 0.075 12.8 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 CDJ59323.1 - 0.077 12.7 0.5 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 CDJ59323.1 - 0.12 12.3 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 CDJ59323.1 - 0.14 11.8 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDJ59323.1 - 0.17 12.2 0.2 0.17 12.2 0.2 1.5 2 0 0 2 2 1 0 AAA domain Septin PF00735.18 CDJ59323.1 - 0.21 10.8 0.1 0.26 10.5 0.1 1.1 1 0 0 1 1 1 0 Septin HNF-1_N PF04814.13 CDJ59323.1 - 0.24 12.0 3.1 0.32 11.6 3.1 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CCSAP PF15748.5 CDJ59323.1 - 0.24 11.5 4.8 0.3 11.2 4.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ATPase_2 PF01637.18 CDJ59323.1 - 0.26 11.2 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CDJ59323.1 - 0.28 11.4 0.3 0.28 11.4 0.3 1.9 2 0 0 2 2 2 0 AAA domain Pex14_N PF04695.13 CDJ59323.1 - 0.38 11.4 9.0 0.64 10.7 9.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_14 PF13173.6 CDJ59323.1 - 0.6 10.1 0.1 0.6 10.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain DUF4366 PF14283.6 CDJ59323.1 - 1.8 8.6 3.5 4.6 7.3 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3043 PF11241.8 CDJ59323.1 - 3.1 7.8 5.4 3.9 7.5 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2057 PF09829.9 CDJ59323.1 - 3.2 7.9 8.7 3.8 7.6 8.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SOG2 PF10428.9 CDJ59323.1 - 3.4 6.8 9.0 3.4 6.7 9.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CDK2AP PF09806.9 CDJ59323.1 - 4.6 7.2 11.9 6.8 6.7 11.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CAP_N PF01213.19 CDJ59323.1 - 6 6.3 11.4 8.2 5.8 11.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CobT PF06213.12 CDJ59325.1 - 0.76 9.1 21.3 0.75 9.1 21.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 CDJ59325.1 - 9.5 4.0 5.7 9.2 4.0 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hamartin PF04388.12 CDJ59326.1 - 7 5.2 11.8 9.2 4.8 11.8 1.2 1 0 0 1 1 1 0 Hamartin protein Notch PF00066.17 CDJ59328.1 - 5.4e-05 23.6 8.6 5.4e-05 23.6 8.6 3.6 2 0 0 2 2 2 1 LNR domain Big_5 PF13205.6 CDJ59328.1 - 0.00012 22.7 0.0 0.51 11.0 0.0 4.5 4 0 0 4 4 4 1 Bacterial Ig-like domain FG-GAP PF01839.23 CDJ59328.1 - 1.5 9.0 7.8 7.8 6.7 0.4 4.1 3 0 0 3 3 3 0 FG-GAP repeat SR-25 PF10500.9 CDJ59330.1 - 0.00063 19.4 10.2 0.00063 19.4 10.2 4.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein RWD PF05773.22 CDJ59330.1 - 0.015 15.6 0.0 0.072 13.4 0.0 2.1 2 0 0 2 2 2 0 RWD domain TFIIA PF03153.13 CDJ59330.1 - 0.13 12.2 28.1 1.2 9.1 13.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDJ59330.1 - 0.23 10.0 21.1 0.28 9.7 9.2 2.6 2 1 0 2 2 2 0 Macoilin family Pkinase PF00069.25 CDJ59331.1 - 3.9e-08 33.0 2.9 2.6e-07 30.3 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59331.1 - 0.0022 17.3 0.1 0.011 15.0 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Spore_YhcN_YlaJ PF09580.10 CDJ59331.1 - 0.047 13.8 0.2 0.047 13.8 0.2 3.4 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ribosomal_S18 PF01084.20 CDJ59333.1 - 2.3e-10 40.5 0.1 5.3e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 RNA_pol_3_Rpc31 PF11705.8 CDJ59334.1 - 9.2e-05 22.8 6.7 0.00019 21.8 6.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 CDJ59334.1 - 0.00011 21.1 5.9 0.00016 20.6 5.9 1.3 1 0 0 1 1 1 1 Presenilin Spt20 PF12090.8 CDJ59334.1 - 0.00026 20.7 28.2 0.0011 18.6 19.3 2.3 2 0 0 2 2 2 1 Spt20 family PNISR PF15996.5 CDJ59334.1 - 0.00091 19.6 14.4 0.0069 16.7 7.7 2.4 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DUF2722 PF10846.8 CDJ59334.1 - 0.00095 18.2 14.4 0.00095 18.2 14.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) AAR2 PF05282.11 CDJ59334.1 - 0.0035 16.8 2.2 0.0048 16.4 2.2 1.2 1 0 0 1 1 1 1 AAR2 protein DUF4834 PF16118.5 CDJ59334.1 - 0.0041 18.0 15.4 0.013 16.4 10.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF4746 PF15928.5 CDJ59334.1 - 0.0047 16.4 6.8 0.0047 16.4 6.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) FAM176 PF14851.6 CDJ59334.1 - 0.0081 15.8 7.4 0.0081 15.8 7.4 2.4 2 0 0 2 2 2 1 FAM176 family DUF2052 PF09747.9 CDJ59334.1 - 0.0087 16.2 9.0 0.0087 16.2 9.0 2.4 3 0 0 3 3 2 1 Coiled-coil domain containing protein (DUF2052) Hydrolase PF00702.26 CDJ59334.1 - 0.0099 16.2 9.8 0.0099 16.2 9.8 2.1 1 1 1 2 2 1 1 haloacid dehalogenase-like hydrolase Connexin PF00029.19 CDJ59334.1 - 0.011 15.5 2.5 0.011 15.5 2.5 2.0 2 0 0 2 2 2 0 Connexin Nucleo_P87 PF07267.11 CDJ59334.1 - 0.015 14.2 5.9 0.021 13.7 5.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neur_chan_memb PF02932.16 CDJ59334.1 - 0.016 15.2 7.4 0.024 14.7 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 CDJ59334.1 - 0.026 12.8 2.6 0.065 11.5 0.7 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Afi1 PF07792.12 CDJ59334.1 - 0.027 14.9 7.1 0.027 14.9 7.1 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SLC12 PF03522.15 CDJ59334.1 - 0.045 12.8 8.6 0.06 12.4 8.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Radial_spoke PF04712.12 CDJ59334.1 - 0.059 12.3 9.7 0.08 11.9 5.1 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein SAPS PF04499.15 CDJ59334.1 - 0.096 11.4 7.5 0.13 11.0 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 CDJ59334.1 - 0.13 11.7 14.4 0.07 12.6 8.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PPL5 PF18168.1 CDJ59334.1 - 0.14 11.4 6.5 0.13 11.5 4.2 1.9 2 0 0 2 2 2 0 Prim-pol family 5 Peroxin-3 PF04882.12 CDJ59334.1 - 0.14 11.1 12.5 0.23 10.4 12.5 1.2 1 0 0 1 1 1 0 Peroxin-3 TRAP_alpha PF03896.16 CDJ59334.1 - 0.2 10.8 7.1 0.076 12.2 3.1 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit EPL1 PF10513.9 CDJ59334.1 - 0.28 11.6 14.0 0.056 13.8 5.2 2.5 3 0 0 3 3 2 0 Enhancer of polycomb-like Coilin_N PF15862.5 CDJ59334.1 - 0.4 10.5 19.8 0.073 12.9 10.3 2.4 2 0 0 2 2 2 0 Coilin N-terminus DUF768 PF05589.11 CDJ59334.1 - 0.43 10.6 0.0 0.43 10.6 0.0 2.9 4 0 0 4 4 1 0 Protein of unknown function (DUF768) Utp14 PF04615.13 CDJ59334.1 - 0.44 9.1 19.2 0.049 12.2 12.8 1.8 2 0 0 2 2 2 0 Utp14 protein Peptidase_S49_N PF08496.10 CDJ59334.1 - 0.57 10.2 14.8 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2681 PF10883.8 CDJ59334.1 - 0.59 10.6 22.9 2.5 8.6 12.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CPSF100_C PF13299.6 CDJ59334.1 - 0.6 10.3 16.0 0.067 13.4 5.6 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 CDJ59334.1 - 0.63 9.0 7.3 0.11 11.5 2.9 1.8 2 0 0 2 2 2 0 CLN3 protein MRP-S31 PF15433.6 CDJ59334.1 - 0.63 9.6 15.8 0.096 12.3 8.4 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Serinc PF03348.15 CDJ59334.1 - 0.71 8.7 11.8 2.1 7.2 11.7 1.7 1 1 1 2 2 2 0 Serine incorporator (Serinc) Thg1C PF14413.6 CDJ59334.1 - 0.93 9.7 9.4 5.7 7.1 5.2 2.4 2 0 0 2 2 2 0 Thg1 C terminal domain EFTUD2 PF16004.5 CDJ59334.1 - 1 10.0 19.4 0.074 13.6 9.1 2.7 3 0 0 3 3 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus NPR3 PF03666.13 CDJ59334.1 - 1.3 7.7 12.8 0.18 10.6 8.2 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 CDJ59334.1 - 1.5 9.1 18.2 0.58 10.4 11.0 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein O-antigen_lig PF13425.6 CDJ59334.1 - 1.5 7.5 5.7 0.061 12.1 0.2 1.4 2 0 0 2 2 1 0 O-antigen ligase like membrane protein Rxt3 PF08642.10 CDJ59334.1 - 1.7 9.4 5.1 2.4 9.0 1.6 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 BORG_CEP PF14957.6 CDJ59334.1 - 1.7 9.8 9.4 2.1 9.5 5.5 2.2 2 0 0 2 2 2 0 Cdc42 effector RPN2_C PF18004.1 CDJ59334.1 - 2 8.3 21.5 0.14 12.1 11.5 2.5 3 0 0 3 3 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CTU2 PF10288.9 CDJ59334.1 - 2 8.7 20.6 1.3 9.3 12.5 2.5 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PRC2_HTH_1 PF18118.1 CDJ59334.1 - 2.1 9.2 12.6 5.4 7.9 8.2 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Orf78 PF06024.12 CDJ59334.1 - 3.1 8.2 5.9 5.9 7.3 2.7 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Cellulose_synt PF03552.14 CDJ59334.1 - 3.3 6.1 4.5 5.2 5.4 4.5 1.3 1 0 0 1 1 1 0 Cellulose synthase TMEM51 PF15345.6 CDJ59334.1 - 3.4 7.4 16.7 0.5 10.2 8.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 NEMP PF10225.9 CDJ59334.1 - 3.7 7.1 6.5 2.5 7.7 2.7 2.1 2 0 0 2 2 2 0 NEMP family DUF719 PF05334.13 CDJ59334.1 - 3.8 7.7 17.6 3.5 7.8 7.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF5523 PF17661.1 CDJ59334.1 - 4.1 7.0 20.8 2.5 7.7 13.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF775 PF05603.12 CDJ59334.1 - 4.2 6.9 10.3 6.8 6.2 6.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF4820 PF16091.5 CDJ59334.1 - 4.5 6.6 21.9 11 5.3 21.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) XAP5 PF04921.14 CDJ59334.1 - 4.8 6.9 12.8 14 5.4 8.0 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator PEX11 PF05648.14 CDJ59334.1 - 4.8 6.6 6.6 3.9 6.9 1.4 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Folate_carrier PF01770.18 CDJ59334.1 - 5.3 5.7 8.4 2.3 6.9 4.5 1.9 2 0 0 2 2 2 0 Reduced folate carrier dsRBD2 PF17842.1 CDJ59334.1 - 5.6 7.2 13.7 1.8 8.8 7.7 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Baculo_PP31 PF05311.11 CDJ59334.1 - 6.2 6.2 11.7 2.8 7.3 7.6 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) EIIBC-GUT_N PF03612.14 CDJ59334.1 - 6.2 6.5 15.3 0.71 9.6 6.4 2.6 3 0 0 3 3 2 0 Sorbitol phosphotransferase enzyme II N-terminus RAB3GAP2_N PF14655.6 CDJ59334.1 - 6.3 6.0 11.0 18 4.5 0.1 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CDC45 PF02724.14 CDJ59334.1 - 6.4 4.9 16.5 4.8 5.4 12.5 2.0 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ59334.1 - 6.5 6.5 22.6 0.54 10.0 11.7 2.4 3 0 0 3 3 2 0 Ryanodine Receptor TM 4-6 G0-G1_switch_2 PF15103.6 CDJ59334.1 - 7 7.1 12.6 16 6.0 7.3 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF3408 PF11888.8 CDJ59334.1 - 7 6.8 18.1 7 6.8 10.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Med17 PF10156.9 CDJ59334.1 - 8.2 5.0 21.2 1.2 7.8 8.0 2.1 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Slu7 PF11708.8 CDJ59334.1 - 9.1 5.9 22.7 0.24 11.1 11.3 2.5 3 0 0 3 3 2 0 Pre-mRNA splicing Prp18-interacting factor ORC_WH_C PF18137.1 CDJ59334.1 - 9.4 6.3 20.8 1.8 8.6 11.0 3.0 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal RICTOR_N PF14664.6 CDJ59334.1 - 9.5 5.1 8.6 23 3.8 8.6 1.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term TPH PF13868.6 CDJ59336.1 - 3.6e-47 160.6 150.3 3.6e-47 160.6 150.3 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RPAP2_Rtr1 PF04181.13 CDJ59337.1 - 1.1e-07 32.1 1.6 1.1e-07 32.1 1.6 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family Cpn10 PF00166.21 CDJ59338.1 - 1.9e-15 56.7 0.0 2.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ThiF PF00899.21 CDJ59339.1 - 1.1e-44 152.7 0.1 1.8e-44 152.0 0.1 1.3 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CDJ59339.1 - 0.0011 19.3 0.2 1.9 8.8 0.0 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDJ59339.1 - 0.012 16.0 0.0 0.05 14.1 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Arm PF00514.23 CDJ59340.1 - 4.8e-06 26.4 14.2 0.31 11.2 0.0 9.7 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDJ59340.1 - 0.00053 20.3 12.5 0.014 15.8 0.1 6.0 4 1 1 5 5 5 2 HEAT repeats DUF913 PF06025.12 CDJ59340.1 - 0.097 11.6 0.1 0.85 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) AAA PF00004.29 CDJ59342.1 - 7.6e-29 100.8 0.0 9.4e-26 90.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CDJ59342.1 - 8.6e-14 51.7 0.0 2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CDJ59342.1 - 4.2e-06 27.2 0.2 0.067 13.6 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 CDJ59342.1 - 4.2e-05 23.4 0.2 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_lid_3 PF17862.1 CDJ59342.1 - 0.001 18.8 0.0 0.22 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 CDJ59342.1 - 0.002 18.4 1.8 1.3 9.3 0.1 3.5 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CDJ59342.1 - 0.0025 18.0 0.1 0.047 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDJ59342.1 - 0.012 15.9 0.0 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 CDJ59342.1 - 0.019 15.0 0.6 0.46 10.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CDJ59342.1 - 0.02 14.9 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CDJ59342.1 - 0.068 12.9 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CDJ59342.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 CDJ59342.1 - 0.17 11.3 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF2722 PF10846.8 CDJ59342.1 - 0.65 8.9 9.1 0.012 14.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4611 PF15387.6 CDJ59343.1 - 0.0016 18.6 3.5 0.0025 18.0 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 CDJ59343.1 - 0.029 14.2 0.6 0.049 13.4 0.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 CDJ59343.1 - 0.11 12.9 10.5 0.69 10.3 9.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 CDJ59343.1 - 0.16 12.0 4.0 0.13 12.2 0.6 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 CDJ59343.1 - 0.18 11.4 1.9 0.95 9.1 0.2 2.5 3 0 0 3 3 3 0 FAM176 family DUF3245 PF11595.8 CDJ59343.1 - 0.35 11.3 7.1 0.2 12.1 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) WRNPLPNID PF15017.6 CDJ59343.1 - 0.57 11.1 6.8 1.4 9.8 0.2 2.7 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Cwf_Cwc_15 PF04889.12 CDJ59343.1 - 4.4 6.9 14.3 11 5.7 14.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CDJ59343.1 - 5.8 6.5 7.5 5.5 6.5 4.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PHD PF00628.29 CDJ59344.1 - 1.1e-07 31.6 14.1 1e-05 25.3 6.2 2.4 2 0 0 2 2 2 2 PHD-finger DUF4710 PF15828.5 CDJ59344.1 - 0.00021 21.3 2.5 0.00021 21.3 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4710) zf-HC5HC2H PF13771.6 CDJ59344.1 - 0.0013 18.9 2.7 0.003 17.8 2.7 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDJ59344.1 - 0.024 14.8 2.8 0.048 13.8 2.4 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain DUF3725 PF12523.8 CDJ59344.1 - 0.12 12.7 0.2 0.33 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Rubredoxin PF00301.20 CDJ59344.1 - 0.41 10.7 12.1 0.75 9.9 3.4 2.7 2 0 0 2 2 2 0 Rubredoxin zf-4CXXC_R1 PF10497.9 CDJ59344.1 - 0.44 10.8 10.5 1.7 8.9 4.2 2.5 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-MIZ PF02891.20 CDJ59344.1 - 0.47 10.3 6.1 1.4 8.7 0.3 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PHD_4 PF16866.5 CDJ59344.1 - 0.57 10.3 15.5 0.23 11.6 8.7 3.1 2 1 0 2 2 2 0 PHD-finger Rad50_zn_hook PF04423.14 CDJ59344.1 - 1.8 8.5 7.0 2.1 8.3 0.2 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif PHD_2 PF13831.6 CDJ59344.1 - 3.6 7.2 12.2 1.5 8.4 1.8 3.0 3 0 0 3 3 3 0 PHD-finger zf-RING_2 PF13639.6 CDJ59344.1 - 5.1 7.5 14.2 0.67 10.3 6.7 2.6 2 0 0 2 2 2 0 Ring finger domain RskA PF10099.9 CDJ59345.1 - 2.3e-13 50.8 1.1 1.9e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Anti-sigma-K factor rskA TMEM51 PF15345.6 CDJ59345.1 - 0.0084 16.0 2.6 0.0084 16.0 2.6 2.9 2 1 1 3 3 3 1 Transmembrane protein 51 Utp14 PF04615.13 CDJ59345.1 - 0.0084 14.7 27.9 0.012 14.3 28.0 1.2 1 0 0 1 1 1 1 Utp14 protein Conotoxin PF02950.17 CDJ59345.1 - 0.07 14.1 1.0 0.07 14.1 1.0 3.7 3 1 0 3 3 3 0 Conotoxin DUF4834 PF16118.5 CDJ59345.1 - 0.084 13.8 0.3 0.084 13.8 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Lig_chan PF00060.26 CDJ59345.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel PUCC PF03209.15 CDJ59345.1 - 1.5 7.7 8.3 4.9 6.0 2.8 2.3 2 0 0 2 2 2 0 PUCC protein 7tm_3 PF00003.22 CDJ59345.1 - 2.6 7.7 5.4 1.7 8.3 0.4 2.1 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Cwf_Cwc_15 PF04889.12 CDJ59345.1 - 6.1 6.5 35.7 1.1 8.9 24.9 2.4 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein KH_1 PF00013.29 CDJ59348.1 - 2.8e-23 81.5 0.0 4e-07 29.8 0.0 4.2 4 0 0 4 4 4 4 KH domain PTS_2-RNA PF01885.16 CDJ59350.1 - 2.5e-41 141.7 0.0 1.1e-40 139.6 0.0 1.9 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3710 PF12502.8 CDJ59350.1 - 0.37 10.4 7.7 0.68 9.6 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3710) SUIM_assoc PF16619.5 CDJ59351.1 - 0.022 14.8 4.1 0.022 14.8 4.1 3.7 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Sdh5 PF03937.16 CDJ59351.1 - 0.027 14.4 0.2 0.088 12.8 0.2 1.9 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase BORG_CEP PF14957.6 CDJ59351.1 - 1.7 9.8 5.2 0.81 10.9 0.7 2.5 3 0 0 3 3 3 0 Cdc42 effector Spt20 PF12090.8 CDJ59351.1 - 5.1 6.6 14.9 0.38 10.3 5.9 2.3 2 0 0 2 2 2 0 Spt20 family CSN8_PSD8_EIF3K PF10075.9 CDJ59352.1 - 5.8e-14 52.3 0.1 2.9e-13 50.0 0.1 1.9 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Uds1 PF15456.6 CDJ59352.1 - 0.094 12.9 1.2 0.17 12.0 1.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation SSP160 PF06933.11 CDJ59352.1 - 0.11 10.7 10.8 0.14 10.4 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 CDJ59352.1 - 0.29 10.7 12.2 0.41 10.2 12.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 CDJ59352.1 - 1.3 8.0 5.2 1.7 7.6 5.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF515 PF04415.12 CDJ59352.1 - 7.9 4.7 9.6 12 4.1 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sec7_N PF12783.7 CDJ59353.1 - 4.3e-11 43.0 3.7 4.3e-11 43.0 3.7 3.6 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SUIM_assoc PF16619.5 CDJ59353.1 - 0.29 11.2 0.0 0.29 11.2 0.0 18.9 14 4 2 16 16 16 0 Unstructured region C-term to UIM in Ataxin3 SID-1_RNA_chan PF13965.6 CDJ59354.1 - 0.44 8.9 4.6 6.7 5.0 0.0 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CNOT1_CAF1_bind PF16415.5 CDJ59355.1 - 1.2e-24 87.0 2.0 2.5e-12 46.7 0.1 3.5 1 1 2 3 3 3 3 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CDJ59355.1 - 5.5e-21 75.0 4.3 3.9e-14 52.8 1.6 6.6 5 2 1 6 6 6 2 Domain of unknown function (DUF3819) Pex14_N PF04695.13 CDJ59355.1 - 0.00025 21.7 26.2 0.0015 19.2 16.2 11.5 10 3 1 12 12 12 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 CDJ59355.1 - 0.14 11.1 26.7 0.037 13.0 4.3 3.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) HCO3_cotransp PF00955.21 CDJ59355.1 - 1.3 7.8 13.0 0.33 9.7 1.0 2.3 2 0 0 2 2 2 0 HCO3- transporter family TT_ORF1 PF02956.14 CDJ59355.1 - 1.7 7.2 22.9 1.5 7.4 7.1 2.6 2 0 0 2 2 2 0 TT viral orf 1 ASC PF00858.24 CDJ59355.1 - 1.7 7.5 15.9 1.4 7.8 2.5 2.4 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel CDC45 PF02724.14 CDJ59355.1 - 2.1 6.5 33.8 0.0068 14.8 2.9 2.8 3 0 0 3 3 3 0 CDC45-like protein Na_trans_assoc PF06512.13 CDJ59355.1 - 7.1 6.9 23.4 0.39 11.0 5.7 3.2 3 0 0 3 3 3 0 Sodium ion transport-associated CNDH2_C PF16858.5 CDJ59356.1 - 0.038 13.9 1.5 0.059 13.2 1.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SelK_SelG PF10961.8 CDJ59356.1 - 5 7.8 15.8 1.3 9.7 12.0 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PC_rep PF01851.22 CDJ59357.1 - 1.4e-16 60.0 10.1 7.2e-06 26.2 0.5 5.0 4 0 0 4 4 4 4 Proteasome/cyclosome repeat BAF1_ABF1 PF04684.13 CDJ59357.1 - 0.012 14.7 8.3 0.018 14.1 8.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SUIM_assoc PF16619.5 CDJ59357.1 - 0.018 15.1 6.4 0.018 15.1 6.4 3.1 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 CDJ59357.1 - 0.029 14.0 5.7 0.051 13.2 5.7 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DDHD PF02862.17 CDJ59357.1 - 0.034 14.3 4.8 0.064 13.4 4.8 1.4 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 CDJ59357.1 - 0.048 11.9 12.3 0.058 11.7 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF913 PF06025.12 CDJ59357.1 - 0.056 12.4 4.6 0.085 11.8 4.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Baculo_PP31 PF05311.11 CDJ59357.1 - 0.18 11.2 2.9 0.29 10.6 2.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Presenilin PF01080.17 CDJ59357.1 - 0.38 9.5 10.6 0.6 8.8 10.6 1.3 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CDJ59357.1 - 0.68 7.8 8.7 0.92 7.3 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDJ59357.1 - 0.95 9.6 18.8 1.7 8.7 18.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 CDJ59357.1 - 1.2 9.2 8.9 1.9 8.5 8.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ59357.1 - 1.8 7.3 5.8 2.4 6.9 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IER PF05760.12 CDJ59357.1 - 2 8.6 27.4 0.049 13.9 19.0 2.0 2 0 0 2 2 2 0 Immediate early response protein (IER) Ndc1_Nup PF09531.10 CDJ59357.1 - 2.3 6.8 11.7 3.6 6.2 11.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CDJ59357.1 - 2.9 7.4 18.1 4.8 6.7 18.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ59357.1 - 3.5 7.5 38.4 8.8 6.2 38.4 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ59357.1 - 3.7 6.8 21.3 7.2 5.9 21.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR1 PF08505.10 CDJ59357.1 - 3.9 7.7 12.3 6.9 6.9 12.3 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CwfJ_C_2 PF04676.14 CDJ59357.1 - 4.5 8.2 6.4 2.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 Tim54 PF11711.8 CDJ59357.1 - 5.4 5.7 10.6 8.3 5.1 10.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 CDJ59357.1 - 6.8 5.6 9.7 9.9 5.1 9.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 CDJ59357.1 - 9 5.4 6.4 14 4.8 6.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SR-25 PF10500.9 CDJ59358.1 - 0.002 17.8 18.7 0.002 17.8 18.7 7.4 4 2 2 7 7 7 2 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.8 CDJ59358.1 - 0.0028 16.7 9.8 0.0028 16.7 9.8 7.1 6 1 1 7 7 7 1 Transcriptional activator LAG-3 Lin-8 PF03353.15 CDJ59358.1 - 0.0056 16.3 22.0 0.0056 16.3 22.0 5.1 6 0 0 6 6 6 3 Ras-mediated vulval-induction antagonist Utp14 PF04615.13 CDJ59358.1 - 4.1 5.8 46.3 0.59 8.6 33.3 2.5 1 1 0 2 2 2 0 Utp14 protein Pkinase PF00069.25 CDJ59360.1 - 5.8e-09 35.7 0.0 1.9e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59360.1 - 0.00014 21.3 0.1 0.0004 19.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2722 PF10846.8 CDJ59360.1 - 0.0011 18.0 2.6 0.0015 17.6 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ59360.1 - 0.095 12.3 12.0 0.15 11.6 12.0 1.2 1 0 0 1 1 1 0 Spt20 family PGA2 PF07543.12 CDJ59360.1 - 0.37 10.8 6.9 0.39 10.7 0.4 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 CRF1 PF10380.9 CDJ59360.1 - 0.47 10.8 2.5 0.3 11.4 0.4 1.7 2 0 0 2 2 2 0 Transcription factor CRF1 CCDC53 PF10152.9 CDJ59360.1 - 0.61 10.5 7.5 2.3 8.6 0.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex LRR_10 PF18805.1 CDJ59361.1 - 0.016 14.9 0.1 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeat Ank_3 PF13606.6 CDJ59362.1 - 3.2 8.6 6.8 8.8 7.3 0.0 3.7 2 1 1 3 3 3 0 Ankyrin repeat Ndc80_HEC PF03801.13 CDJ59363.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 3.5 3 1 0 3 3 3 1 HEC/Ndc80p family Spc7 PF08317.11 CDJ59363.1 - 0.0012 17.8 10.1 0.0012 17.8 10.1 3.1 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF812 PF05667.11 CDJ59363.1 - 2.3 7.0 61.0 1.1 8.0 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) tRNA-synt_1 PF00133.22 CDJ59364.1 - 4.4e-46 157.3 0.0 6.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ59364.1 - 1.4e-06 27.3 0.0 1.4e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CDJ59364.1 - 0.076 11.9 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain T2SSI PF02501.17 CDJ59364.1 - 0.089 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Ras PF00071.22 CDJ59366.1 - 2.3e-51 173.6 0.1 3.1e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ59366.1 - 1.5e-32 112.4 0.5 4e-32 110.9 0.0 1.9 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ59366.1 - 5.6e-10 38.9 0.0 7.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ59366.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ59366.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ59366.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDJ59366.1 - 0.29 11.0 5.1 2 8.3 0.6 2.4 2 0 0 2 2 2 0 RsgA GTPase SUIM_assoc PF16619.5 CDJ59367.1 - 0.025 14.6 5.5 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CAF1A PF12253.8 CDJ59368.1 - 0.18 12.0 18.2 0.6 10.3 18.2 1.9 1 1 0 1 1 1 0 Chromatin assembly factor 1 subunit A FAM196 PF15265.6 CDJ59368.1 - 0.19 11.2 6.0 0.35 10.3 6.0 1.4 1 0 0 1 1 1 0 FAM196 family Ribosomal_S21 PF01165.20 CDJ59368.1 - 0.48 10.2 5.6 0.36 10.6 3.4 2.0 2 0 0 2 2 2 0 Ribosomal protein S21 Pkinase PF00069.25 CDJ59370.1 - 1.3e-44 152.6 18.9 3.1e-20 72.6 0.0 5.0 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59370.1 - 2.8e-25 89.1 1.1 1.6e-11 44.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ59370.1 - 4.4e-11 41.5 1.1 0.00019 20.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ59370.1 - 2e-09 36.6 1.3 0.0032 17.3 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ59370.1 - 5.9e-08 31.9 1.7 0.0011 18.4 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDJ59370.1 - 4.8e-07 30.1 0.0 0.052 14.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ59370.1 - 0.00055 19.7 4.9 0.046 13.6 0.2 3.4 3 1 1 4 4 4 2 EF-hand domain pair PH PF00169.29 CDJ59370.1 - 0.031 14.8 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 PH domain DUF572 PF04502.13 CDJ59370.1 - 0.13 11.8 0.0 0.13 11.8 0.0 4.5 3 2 1 4 4 4 0 Family of unknown function (DUF572) TBCC PF07986.12 CDJ59372.1 - 3.5e-12 46.1 0.3 7.6e-12 45.0 0.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 CDJ59372.1 - 0.0064 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CRM1_repeat_2 PF18784.1 CDJ59374.1 - 9.5e-18 63.6 0.5 1.6e-17 62.9 0.5 1.4 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 CDJ59374.1 - 9.6e-18 64.7 1.1 1.4e-17 64.1 0.1 1.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 CDJ59374.1 - 1.6e-10 40.7 0.0 4.3e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 CDJ59374.1 - 4.8e-06 26.0 0.1 9.2e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Rcd1 PF04078.13 CDJ59375.1 - 9.8e-14 51.3 0.0 9.8e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like KR PF08659.10 CDJ59377.1 - 3.4e-51 173.7 0.0 1.3e-50 171.8 0.0 2.0 1 1 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 CDJ59377.1 - 7e-45 153.6 1.6 1.8e-40 139.1 0.8 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CDJ59377.1 - 3.8e-41 141.3 0.1 1.1e-40 139.7 0.1 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CDJ59377.1 - 2.2e-39 135.8 2.2 2.2e-39 135.8 2.2 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CDJ59377.1 - 1.2e-35 122.1 0.1 3.8e-35 120.5 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 CDJ59377.1 - 8.4e-13 48.5 0.2 1.8e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CDJ59377.1 - 5.2e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 CDJ59377.1 - 7.9e-05 23.1 0.0 0.00023 21.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF4723 PF15851.5 CDJ59377.1 - 0.097 12.8 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4723) Cwf_Cwc_15 PF04889.12 CDJ59378.1 - 0.15 11.8 16.3 0.19 11.4 16.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CDJ59378.1 - 0.54 8.3 12.9 0.67 8.0 12.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CDJ59378.1 - 1.4 7.0 12.3 1.4 7.0 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 CDJ59378.1 - 2.8 7.5 11.5 3.6 7.1 11.5 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 CDJ59378.1 - 3.1 6.0 11.3 3.4 5.8 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CDJ59378.1 - 4 6.1 5.7 4.7 5.9 5.7 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CDJ59378.1 - 6.3 5.5 7.7 7.8 5.2 7.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 CDJ59378.1 - 7.6 5.8 6.5 10 5.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DEAD PF00270.29 CDJ59379.1 - 9.1e-34 116.7 0.0 2.2e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ59379.1 - 1.3e-23 83.5 0.0 2.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ59379.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ59379.1 - 0.033 14.4 0.0 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ59380.1 - 2.1e-24 86.6 0.1 3e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDJ59380.1 - 1.4e-05 25.1 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDJ59380.1 - 8.1e-05 23.1 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ59380.1 - 9.9e-05 22.3 0.3 0.00018 21.5 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CDJ59380.1 - 0.00015 21.5 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ59380.1 - 0.00093 18.9 0.4 0.0019 17.9 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CDJ59380.1 - 0.003 18.1 0.0 0.0053 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CDJ59380.1 - 0.0052 16.9 0.7 0.0098 16.0 0.7 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CDJ59380.1 - 0.0092 15.7 0.0 0.034 13.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 CDJ59380.1 - 0.0095 16.0 1.2 0.014 15.5 0.5 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 CDJ59380.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDJ59380.1 - 0.036 13.3 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CDJ59380.1 - 0.045 13.5 0.3 0.094 12.4 0.3 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CDJ59380.1 - 0.055 12.4 0.8 0.13 11.2 0.5 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 CDJ59380.1 - 0.074 12.5 0.0 0.72 9.3 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4158 PF13700.6 CDJ59380.1 - 0.092 12.6 0.0 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) AAA_22 PF13401.6 CDJ59380.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CDJ59380.1 - 0.16 12.0 0.4 0.29 11.2 0.4 1.6 1 1 0 1 1 1 0 Dynamin family APS_kinase PF01583.20 CDJ59380.1 - 0.18 11.7 0.1 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC2_membrane PF01061.24 CDJ59381.1 - 3e-26 92.2 4.8 4.1e-26 91.7 4.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CDJ59381.1 - 6.4e-07 28.8 3.9 9.2e-07 28.3 3.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein T2SSF PF00482.23 CDJ59383.1 - 0.08 12.9 1.8 5.9 6.9 0.1 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Sec20 PF03908.13 CDJ59383.1 - 0.13 12.2 2.2 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 Sec20 TBCA PF02970.16 CDJ59383.1 - 0.17 12.3 6.4 4.3 7.7 0.1 3.3 3 0 0 3 3 3 0 Tubulin binding cofactor A KxDL PF10241.9 CDJ59383.1 - 4.5 7.6 10.3 19 5.6 2.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein RasGAP_C PF03836.15 CDJ59383.1 - 5 7.3 9.0 5.1 7.2 1.7 2.6 2 0 0 2 2 2 0 RasGAP C-terminus LMBR1 PF04791.16 CDJ59384.1 - 2.4e-08 33.4 0.0 4.2e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein CD225 PF04505.12 CDJ59384.1 - 0.088 13.0 0.2 0.088 13.0 0.2 4.2 5 0 0 5 5 5 0 Interferon-induced transmembrane protein DUF2207 PF09972.9 CDJ59384.1 - 0.44 9.3 1.1 4.7 5.9 0.9 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S8 PF00082.22 CDJ59385.1 - 9.6e-42 143.3 5.4 2.3e-41 142.0 5.4 1.6 1 0 0 1 1 1 1 Subtilase family PAP2 PF01569.21 CDJ59386.1 - 0.43 10.3 2.1 12 5.6 0.1 3.2 3 0 0 3 3 3 0 PAP2 superfamily C2 PF00168.30 CDJ59387.1 - 3.8e-11 43.2 0.0 9.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain TF_Zn_Ribbon PF08271.12 CDJ59388.1 - 6.8e-08 31.9 0.3 6.8e-08 31.9 0.3 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CDJ59388.1 - 0.61 9.6 3.8 0.7 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF789 PF05623.12 CDJ59390.1 - 0.17 11.5 0.7 0.21 11.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TFIIA PF03153.13 CDJ59392.1 - 0.057 13.4 16.2 0.063 13.3 16.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KGK PF08872.10 CDJ59392.1 - 2 8.9 10.5 1 9.9 7.1 1.9 1 1 1 2 2 2 0 KGK domain BRF1 PF07741.13 CDJ59392.1 - 3.2 8.1 10.5 2.2 8.7 8.3 1.8 1 1 1 2 2 2 0 Brf1-like TBP-binding domain CNDH2_N PF06278.11 CDJ59392.1 - 3.9 7.7 15.8 0.23 11.7 0.2 2.1 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ribosomal_60s PF00428.19 CDJ59394.1 - 1.2e-21 77.1 11.2 1.5e-21 76.8 11.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hydrolase_4 PF12146.8 CDJ59395.1 - 2.8e-06 26.8 0.0 0.00023 20.5 0.0 3.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ59395.1 - 0.00014 21.6 0.0 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Phi-29_GP16_7 PF06720.11 CDJ59396.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 FAD_binding_3 PF01494.19 CDJ59397.1 - 6.2e-56 190.1 3.4 3.3e-28 98.9 0.3 4.3 3 1 1 5 5 5 3 FAD binding domain Lycopene_cycl PF05834.12 CDJ59397.1 - 0.00011 21.4 0.7 0.00022 20.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CDJ59397.1 - 0.00021 21.0 0.1 0.00068 19.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ59397.1 - 0.00028 21.0 0.4 0.0029 17.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ59397.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ59397.1 - 0.0026 16.5 0.7 0.0044 15.8 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CDJ59397.1 - 0.0027 17.0 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CDJ59397.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CDC45 PF02724.14 CDJ59397.1 - 0.31 9.3 8.6 0.74 8.0 8.6 1.6 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 CDJ59397.1 - 2.6 8.0 14.9 5 7.1 14.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GramPos_pilinD1 PF16555.5 CDJ59397.1 - 5.7 7.1 8.6 15 5.7 8.6 1.6 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain Dcc1 PF09724.9 CDJ59398.1 - 8.2e-10 38.5 0.0 7.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 TMEM208_SND2 PF05620.11 CDJ59399.1 - 0.033 14.0 0.4 0.083 12.7 0.4 1.7 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF4248 PF14053.6 CDJ59399.1 - 0.039 14.0 0.2 0.13 12.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Pkinase PF00069.25 CDJ59401.1 - 1.1e-37 129.9 0.0 1.7e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59401.1 - 1.1e-20 74.0 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ59401.1 - 1.3e-12 48.0 1.6 4.8e-07 30.1 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ59401.1 - 5.5e-10 39.0 2.7 3.5e-06 26.8 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ59401.1 - 6.5e-08 31.6 3.2 0.0026 17.2 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CDJ59401.1 - 6.1e-07 28.9 2.1 0.0084 16.0 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDJ59401.1 - 3.4e-06 26.3 2.7 0.064 12.8 0.4 2.8 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CDJ59401.1 - 2.3e-05 23.9 0.1 4.9e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.7 CDJ59401.1 - 0.2 11.6 3.2 4.9 7.2 0.1 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Topoisom_bac PF01131.20 CDJ59402.1 - 3.6e-28 98.7 0.0 1.2e-14 54.2 0.0 5.0 2 2 3 5 5 5 5 DNA topoisomerase Toprim PF01751.22 CDJ59402.1 - 3e-06 27.4 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Toprim domain TSC22 PF01166.18 CDJ59404.1 - 0.0067 16.7 0.3 0.023 15.0 0.3 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family ACOX PF01756.19 CDJ59404.1 - 3.1 7.3 6.3 2.1 7.9 3.7 1.9 2 0 0 2 2 2 0 Acyl-CoA oxidase Pkinase PF00069.25 CDJ59406.1 - 1.1e-73 247.9 0.0 2e-73 247.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59406.1 - 4.7e-37 127.7 0.0 8.5e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ59406.1 - 7.1e-06 26.1 0.0 7.1e-06 26.1 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDJ59406.1 - 5.1e-05 22.7 0.0 0.00017 21.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ59406.1 - 0.00049 19.5 0.3 0.00097 18.5 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDJ59406.1 - 0.0013 17.8 0.2 0.0013 17.8 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Phosducin PF02114.16 CDJ59406.1 - 0.041 12.8 0.0 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosducin Choline_kinase PF01633.20 CDJ59406.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase UvrD-helicase PF00580.21 CDJ59406.1 - 0.078 12.5 2.5 0.18 11.3 2.5 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain FTA2 PF13095.6 CDJ59406.1 - 0.089 12.4 0.0 0.089 12.4 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YchF-GTPase_C PF06071.13 CDJ59407.1 - 1.8e-37 127.4 0.2 3.6e-29 100.8 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CDJ59407.1 - 1.8e-06 28.0 0.2 1.2e-05 25.3 0.0 2.3 1 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CDJ59407.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 TGS domain Peptidase_S49_N PF08496.10 CDJ59407.1 - 0.24 11.4 3.3 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PRP21_like_P PF12230.8 CDJ59408.1 - 8.1e-21 74.9 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein RRM_1 PF00076.22 CDJ59409.1 - 0.0092 15.8 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mer2 PF09074.10 CDJ59409.1 - 0.039 13.8 0.0 0.072 12.9 0.0 1.4 2 0 0 2 2 2 0 Mer2 NLE PF08154.12 CDJ59410.1 - 0.00013 22.4 0.1 0.00025 21.5 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain SR-25 PF10500.9 CDJ59410.1 - 0.0084 15.7 9.5 0.01 15.5 9.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Foie-gras_1 PF11817.8 CDJ59410.1 - 0.16 11.5 0.4 0.19 11.3 0.4 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 Roughex PF06020.11 CDJ59410.1 - 0.21 10.6 2.4 0.23 10.5 2.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein IMUP PF15761.5 CDJ59410.1 - 0.47 11.2 7.9 0.68 10.6 7.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDJ59410.1 - 1.8 9.1 8.1 2.3 8.7 8.1 1.1 1 0 0 1 1 1 0 Dehydrin Hydrolase_4 PF12146.8 CDJ59411.1 - 6.5e-12 45.2 1.5 7.6e-12 45.0 1.5 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ59411.1 - 2e-10 40.8 0.2 2.2e-10 40.6 0.2 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ59411.1 - 5.7e-09 36.9 1.1 6.7e-09 36.7 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CDJ59411.1 - 0.00023 20.8 0.5 0.00031 20.4 0.5 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Asp2 PF16929.5 CDJ59411.1 - 0.0016 17.5 0.1 0.0019 17.3 0.1 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter SAT PF16073.5 CDJ59411.1 - 0.013 15.3 4.1 0.017 14.9 4.1 1.1 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ribosomal_60s PF00428.19 CDJ59411.1 - 0.018 15.6 6.8 0.025 15.2 6.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chlorophyllase2 PF12740.7 CDJ59411.1 - 0.042 12.8 0.4 0.055 12.4 0.4 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF676 PF05057.14 CDJ59411.1 - 0.13 11.8 0.2 0.31 10.5 0.1 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Stevor PF17410.2 CDJ59411.1 - 0.27 10.7 0.5 0.29 10.6 0.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ABC_tran PF00005.27 CDJ59412.1 - 7.6e-35 120.4 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ59412.1 - 2.9e-13 50.1 0.0 2.9e-13 50.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 CDJ59412.1 - 1.3e-06 28.0 0.2 0.0001 21.8 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CDJ59412.1 - 5.6e-05 23.0 0.1 0.00031 20.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain ABC_ATPase PF09818.9 CDJ59412.1 - 0.00014 20.8 0.1 0.013 14.3 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 CDJ59412.1 - 0.0002 21.0 0.2 0.0051 16.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ59412.1 - 0.00038 20.9 0.1 0.0013 19.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDJ59412.1 - 0.00074 19.9 0.0 0.0035 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ59412.1 - 0.00079 19.7 0.2 0.0063 16.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDJ59412.1 - 0.0044 16.8 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ59412.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ59412.1 - 0.0081 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CDJ59412.1 - 0.01 15.6 0.0 0.14 11.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 CDJ59412.1 - 0.021 14.3 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CDJ59412.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 CDJ59412.1 - 0.026 14.8 0.2 0.077 13.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 CDJ59412.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 CDJ59412.1 - 0.054 13.7 0.3 1.1 9.5 0.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 CDJ59412.1 - 0.059 13.8 0.0 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CDJ59412.1 - 0.072 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 CDJ59412.1 - 0.13 12.1 0.9 1.6 8.6 0.2 2.3 1 1 1 2 2 2 0 NTPase Rad17 PF03215.15 CDJ59412.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 CDJ59412.1 - 0.17 11.9 0.2 0.52 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CDJ59412.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 CDJ59412.1 - 0.39 10.6 1.4 2.4 8.1 1.4 2.1 1 1 0 1 1 1 0 NACHT domain TPR_2 PF07719.17 CDJ59413.1 - 5.9e-06 26.0 2.7 0.00019 21.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ59413.1 - 0.00025 20.7 0.5 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ59413.1 - 0.00081 19.4 0.3 0.064 13.5 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ59413.1 - 0.0018 18.5 0.1 3.8 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ59413.1 - 0.0047 17.0 0.1 1.4 9.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ59413.1 - 0.0066 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ59413.1 - 0.013 16.1 0.6 0.41 11.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4698 PF15769.5 CDJ59414.1 - 0.85 8.6 3.4 1.1 8.2 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SR-25 PF10500.9 CDJ59414.1 - 5.7 6.5 18.7 6.4 6.3 17.2 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Bud13 PF09736.9 CDJ59416.1 - 1.6e-17 64.2 0.3 2.1e-17 63.9 0.3 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex eIF3_subunit PF08597.10 CDJ59417.1 - 0.015 15.3 5.0 0.015 15.3 5.0 3.0 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit Rxt3 PF08642.10 CDJ59417.1 - 0.04 14.7 0.6 0.04 14.7 0.6 4.2 3 2 0 4 4 4 0 Histone deacetylation protein Rxt3 MPM1 PF17234.2 CDJ59417.1 - 1.7 8.9 29.6 1.3 9.3 5.4 3.4 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 CIAPIN1 PF05093.13 CDJ59417.1 - 5.4 7.6 14.0 11 6.6 0.2 3.3 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Lipase_GDSL PF00657.22 CDJ59417.1 - 7.3 6.5 14.3 26 4.7 9.9 3.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase RskA PF10099.9 CDJ59417.1 - 8.5 6.6 48.0 2 8.7 18.1 3.8 2 2 0 2 2 2 0 Anti-sigma-K factor rskA BSP_II PF05432.11 CDJ59418.1 - 0.0039 16.9 9.8 0.0039 16.9 9.8 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) SUIM_assoc PF16619.5 CDJ59418.1 - 0.64 10.1 8.2 7.1 6.8 1.7 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SDA1 PF05285.12 CDJ59418.1 - 9.7 5.5 10.9 0.75 9.2 5.5 1.8 2 0 0 2 2 2 0 SDA1 V_ATPase_I PF01496.19 CDJ59419.1 - 0.023 12.7 20.2 0.029 12.3 20.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CDJ59419.1 - 0.17 10.7 23.5 0.25 10.2 23.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MecA PF05389.12 CDJ59419.1 - 1 8.9 13.9 1.8 8.2 13.9 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) GREB1 PF15782.5 CDJ59419.1 - 2 5.4 17.5 3.1 4.8 17.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MID_MedPIWI PF18296.1 CDJ59419.1 - 2 8.1 21.4 1.2 8.8 19.2 1.7 2 0 0 2 2 2 0 MID domain of medPIWI DUF4484 PF14831.6 CDJ59419.1 - 2.1 8.3 13.0 3.9 7.5 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) OATP PF03137.20 CDJ59419.1 - 2.2 6.5 4.0 3.6 5.8 4.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4518 PF15008.6 CDJ59419.1 - 2.2 7.4 17.3 4 6.6 17.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RR_TM4-6 PF06459.12 CDJ59419.1 - 2.6 7.8 16.9 5.1 6.8 16.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ59419.1 - 2.8 6.9 16.4 4.8 6.1 16.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CDJ59419.1 - 2.8 6.7 20.4 4.7 5.9 20.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Het-C PF07217.11 CDJ59419.1 - 3.2 6.2 10.5 4.8 5.6 10.5 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C eIF-3_zeta PF05091.12 CDJ59419.1 - 4.1 6.3 20.4 6.5 5.6 20.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 CDJ59419.1 - 4.3 6.2 31.8 0.013 14.5 21.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 CDJ59419.1 - 5.5 7.0 16.7 0.75 9.8 11.9 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 CDJ59419.1 - 8 6.5 18.0 17 5.5 18.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) LMBR1 PF04791.16 CDJ59419.1 - 9.5 5.0 15.8 16 4.3 15.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CRAL_TRIO PF00650.20 CDJ59421.1 - 2e-25 89.4 0.0 3.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Gly-zipper_OmpA PF13436.6 CDJ59421.1 - 0.00025 20.7 10.3 0.0038 17.0 1.7 2.5 2 0 0 2 2 2 2 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 CDJ59421.1 - 0.004 16.9 8.4 0.0047 16.6 1.1 2.4 2 0 0 2 2 2 1 YMGG-like Gly-zipper CRAL_TRIO_N PF03765.15 CDJ59421.1 - 0.0066 16.6 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ATF7IP_BD PF16788.5 CDJ59421.1 - 6.8 6.7 7.7 17 5.4 1.8 2.4 2 0 0 2 2 2 0 ATF-interacting protein binding domain DnaJ PF00226.31 CDJ59422.1 - 1.4e-13 50.7 9.0 2.8e-11 43.4 0.1 4.3 5 0 0 5 5 5 2 DnaJ domain Myb_DNA-binding PF00249.31 CDJ59422.1 - 3e-13 49.7 6.0 8.2e-08 32.3 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ59422.1 - 1.3e-06 28.6 11.2 0.0069 16.6 0.0 4.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain SAP PF02037.27 CDJ59423.1 - 9.4e-06 25.3 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain zinc_ribbon_6 PF14599.6 CDJ59424.1 - 7.6e-22 77.1 1.1 7.6e-22 77.1 1.1 4.1 4 0 0 4 4 3 1 Zinc-ribbon zf-RING_2 PF13639.6 CDJ59424.1 - 1.1e-07 32.1 4.6 1.1e-07 32.1 4.6 5.3 3 1 1 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CDJ59424.1 - 3.8e-07 30.0 2.6 3.8e-07 30.0 2.6 4.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-CHY PF05495.12 CDJ59424.1 - 6.7e-07 29.7 14.8 6.7e-07 29.7 14.8 5.3 2 2 1 3 3 2 1 CHY zinc finger zf-RING_5 PF14634.6 CDJ59424.1 - 7.5e-05 22.6 8.1 7.5e-05 22.6 8.1 6.1 3 2 1 4 4 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ59424.1 - 0.00056 19.7 5.2 0.00056 19.7 5.2 5.0 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ59424.1 - 0.0024 17.7 6.5 0.0024 17.7 6.5 5.0 3 2 2 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ59424.1 - 0.0041 16.8 2.0 0.0041 16.8 2.0 5.0 7 0 0 7 7 7 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ59424.1 - 0.0096 16.1 3.9 0.0096 16.1 3.9 5.0 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-WRNIP1_ubi PF18279.1 CDJ59424.1 - 2.2 9.1 7.4 26 5.8 0.1 4.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain SOG2 PF10428.9 CDJ59424.1 - 5 6.2 23.5 8.3 5.5 23.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RabGAP-TBC PF00566.18 CDJ59425.1 - 2.1e-45 155.0 0.1 4.3e-45 154.0 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HA2 PF04408.23 CDJ59426.1 - 8.4e-12 45.3 0.1 1.5e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDJ59426.1 - 1.3e-11 44.9 0.0 1.4e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1645 PF07816.11 CDJ59427.1 - 2.2 8.8 9.7 8.8 6.9 0.1 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) Coiled-coil_56 PF09813.9 CDJ59427.1 - 2.2 8.4 4.8 6.9 6.8 4.8 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 PknG_rubred PF16919.5 CDJ59428.1 - 0.027 14.6 4.1 0.032 14.4 4.1 1.0 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain SR-25 PF10500.9 CDJ59428.1 - 0.037 13.6 23.5 0.043 13.4 23.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF4 PF05236.14 CDJ59428.1 - 0.087 12.6 8.7 0.087 12.6 8.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4228 PF14009.6 CDJ59428.1 - 0.2 12.1 8.3 0.21 12.0 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RSRP PF17069.5 CDJ59428.1 - 0.55 9.8 21.1 0.58 9.7 21.1 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC106 PF15794.5 CDJ59428.1 - 0.58 9.8 12.0 0.65 9.7 12.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 CDJ59428.1 - 0.63 8.1 20.8 0.66 8.0 20.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein N-SET PF11764.8 CDJ59428.1 - 0.85 9.7 9.2 1.2 9.2 9.2 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Corona_nucleoca PF00937.18 CDJ59428.1 - 0.86 8.6 12.7 0.92 8.5 12.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rtf2 PF04641.12 CDJ59428.1 - 1.2 8.4 5.7 1.3 8.3 5.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger SDP_N PF12278.8 CDJ59428.1 - 1.7 8.8 9.1 2 8.5 9.1 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Presenilin PF01080.17 CDJ59428.1 - 2 7.1 7.0 1.9 7.2 7.0 1.0 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ59428.1 - 2 7.2 11.8 2 7.2 11.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ59428.1 - 2.6 7.5 5.4 2.7 7.5 5.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4692 PF15763.5 CDJ59428.1 - 2.7 8.4 11.9 3 8.3 11.9 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Macoilin PF09726.9 CDJ59428.1 - 2.9 6.3 14.1 2.9 6.3 14.1 1.0 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 CDJ59428.1 - 3.2 8.4 10.3 3.8 8.1 10.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.13 CDJ59428.1 - 3.3 5.9 7.2 3.4 5.9 7.2 1.0 1 0 0 1 1 1 0 Menin RNA_pol_Rpc4 PF05132.14 CDJ59428.1 - 4.3 7.7 7.1 5.1 7.5 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 GREB1 PF15782.5 CDJ59428.1 - 9.3 3.2 8.0 9.2 3.2 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pox_A12 PF04651.13 CDJ59428.1 - 9.3 6.3 12.0 11 6.0 12.0 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein Peptidase_S64 PF08192.11 CDJ59429.1 - 2.4 6.5 15.6 4.9 5.5 15.6 1.5 1 0 0 1 1 1 0 Peptidase family S64 Ank PF00023.30 CDJ59430.1 - 2.1e-07 31.1 2.7 0.0064 16.9 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 CDJ59430.1 - 5.1e-06 27.0 4.5 0.0074 16.8 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ59430.1 - 8e-05 22.9 0.2 0.11 12.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ59430.1 - 8.9e-05 23.0 5.4 0.037 14.6 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) LRR_8 PF13855.6 CDJ59430.1 - 0.00027 20.6 3.3 0.00027 20.6 3.3 2.6 3 0 0 3 3 3 1 Leucine rich repeat Ank_3 PF13606.6 CDJ59430.1 - 0.78 10.5 0.0 0.78 10.5 0.0 6.3 8 0 0 8 8 8 0 Ankyrin repeat LRR_4 PF12799.7 CDJ59430.1 - 4.8 7.7 7.6 20 5.8 4.5 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF4776 PF16003.5 CDJ59431.1 - 3.2 6.7 46.6 0.038 13.0 34.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) TFIIA PF03153.13 CDJ59432.1 - 0.00073 19.7 39.8 0.00073 19.7 39.8 5.8 3 2 2 5 5 5 1 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 CDJ59432.1 - 0.017 15.0 0.1 0.055 13.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like FA_hydroxylase PF04116.13 CDJ59432.1 - 1.6 9.1 7.8 3.8 7.9 0.3 3.5 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily zf-U1 PF06220.12 CDJ59433.1 - 1.7e-17 62.9 1.5 2.4e-17 62.4 1.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 CDJ59433.1 - 5.1 7.6 5.2 65 4.1 5.2 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDJ59433.1 - 6.2 7.2 5.7 0.63 10.4 1.3 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GGA_N-GAT PF18308.1 CDJ59436.1 - 7.8 6.2 6.0 1.9 8.2 0.0 3.0 3 1 0 3 3 3 0 GGA N-GAT domain CLTH PF10607.9 CDJ59438.1 - 1.2e-05 25.2 0.0 0.0001 22.2 0.0 2.0 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDJ59438.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 LisH BTB PF00651.31 CDJ59439.1 - 0.016 15.4 0.1 0.048 13.9 0.1 1.8 1 0 0 1 1 1 0 BTB/POZ domain Dus PF01207.17 CDJ59440.1 - 1e-39 136.5 0.0 1.7e-38 132.5 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1768 PF08719.11 CDJ59441.1 - 0.32 11.2 6.5 0.57 10.4 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1768) Met_10 PF02475.16 CDJ59442.1 - 6.8e-40 137.0 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 CDJ59442.1 - 0.0011 18.2 0.1 0.0018 17.5 0.1 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase SAM_MT PF04445.13 CDJ59442.1 - 0.0043 16.5 0.3 0.0073 15.8 0.3 1.4 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_15 PF09445.10 CDJ59442.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DNA_methylase PF00145.17 CDJ59442.1 - 0.048 13.0 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Fmp27 PF10344.9 CDJ59442.1 - 0.11 10.5 0.5 0.16 10.0 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF3040 PF11239.8 CDJ59443.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF1658 PF07871.11 CDJ59445.1 - 0.4 10.7 2.2 0.81 9.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Molydop_binding PF01568.21 CDJ59447.1 - 0.15 12.1 0.9 0.28 11.2 0.9 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RskA PF10099.9 CDJ59449.1 - 6.7e-05 23.3 2.4 8.6e-05 22.9 2.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA EPL1 PF10513.9 CDJ59449.1 - 0.0024 18.3 10.1 0.0026 18.2 10.1 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like GNAT_acetyltr_2 PF13718.6 CDJ59449.1 - 0.0039 16.6 2.9 0.0043 16.5 2.9 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase 2 DDHD PF02862.17 CDJ59449.1 - 0.0045 17.2 7.7 0.0052 17.0 7.7 1.1 1 0 0 1 1 1 1 DDHD domain CDC45 PF02724.14 CDJ59449.1 - 0.016 13.5 19.5 0.018 13.4 19.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CDJ59449.1 - 0.022 14.2 11.4 0.023 14.2 11.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Apt1 PF10351.9 CDJ59449.1 - 0.023 13.6 6.7 0.021 13.7 6.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC27 PF09507.10 CDJ59449.1 - 0.027 13.9 17.4 0.031 13.7 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 CDJ59449.1 - 0.028 14.2 21.3 0.039 13.7 21.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Shadoo PF14999.6 CDJ59449.1 - 0.032 14.3 1.3 0.052 13.7 1.3 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Utp14 PF04615.13 CDJ59449.1 - 0.035 12.7 19.9 0.041 12.5 19.9 1.1 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 CDJ59449.1 - 0.037 12.8 16.0 0.039 12.7 16.0 1.0 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CDJ59449.1 - 0.042 13.8 3.0 0.051 13.5 3.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF4589 PF15252.6 CDJ59449.1 - 0.042 13.9 7.5 0.063 13.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) O-antigen_lig PF13425.6 CDJ59449.1 - 0.042 12.6 6.0 0.051 12.4 6.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Nop14 PF04147.12 CDJ59449.1 - 0.045 12.0 19.1 0.049 11.9 19.1 1.0 1 0 0 1 1 1 0 Nop14-like family MAJIN PF15077.6 CDJ59449.1 - 0.05 13.4 8.9 0.059 13.2 8.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SDA1 PF05285.12 CDJ59449.1 - 0.067 12.6 19.0 0.073 12.5 19.0 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 CDJ59449.1 - 0.073 12.5 28.7 0.092 12.1 28.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 CDJ59449.1 - 0.074 11.8 10.7 0.072 11.9 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BAF1_ABF1 PF04684.13 CDJ59449.1 - 0.078 12.0 19.3 0.093 11.8 19.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PGA2 PF07543.12 CDJ59449.1 - 0.08 12.9 24.2 0.12 12.4 24.2 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4175 PF13779.6 CDJ59449.1 - 0.14 10.0 19.8 0.16 9.9 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PTPRCAP PF15713.5 CDJ59449.1 - 0.15 12.4 24.6 0.19 12.0 24.6 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 CDJ59449.1 - 0.17 11.9 5.0 0.18 11.8 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PCM1_C PF15717.5 CDJ59449.1 - 0.18 10.5 17.3 0.21 10.2 17.3 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Spt20 PF12090.8 CDJ59449.1 - 0.18 11.4 30.3 0.27 10.8 30.3 1.2 1 0 0 1 1 1 0 Spt20 family DNA_pol_phi PF04931.13 CDJ59449.1 - 0.18 9.9 18.0 0.23 9.5 18.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Med13_C PF06333.12 CDJ59449.1 - 0.19 11.0 7.9 0.23 10.7 7.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Lin-8 PF03353.15 CDJ59449.1 - 0.2 11.2 13.9 0.21 11.1 13.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec62 PF03839.16 CDJ59449.1 - 0.2 11.1 7.1 0.21 11.1 7.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MCM_bind PF09739.9 CDJ59449.1 - 0.21 10.0 13.2 0.22 9.9 13.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Connexin PF00029.19 CDJ59449.1 - 0.21 11.3 7.7 0.24 11.1 7.7 1.1 1 0 0 1 1 1 0 Connexin MDM10 PF12519.8 CDJ59449.1 - 0.22 10.3 7.4 0.21 10.4 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5523 PF17661.1 CDJ59449.1 - 0.24 11.1 17.9 0.27 10.9 17.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Rrn6 PF10214.9 CDJ59449.1 - 0.24 9.8 12.0 0.27 9.7 12.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mpp10 PF04006.12 CDJ59449.1 - 0.25 9.7 24.7 0.3 9.5 24.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Membralin PF09746.9 CDJ59449.1 - 0.26 10.3 2.6 0.24 10.4 2.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein TFIIF_alpha PF05793.12 CDJ59449.1 - 0.27 9.8 19.0 0.31 9.6 19.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 CDJ59449.1 - 0.27 10.6 26.5 0.34 10.2 26.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pox_Ag35 PF03286.14 CDJ59449.1 - 0.33 10.7 19.3 0.54 10.0 19.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S49_N PF08496.10 CDJ59449.1 - 0.46 10.5 6.8 0.61 10.1 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PNISR PF15996.5 CDJ59449.1 - 0.47 10.7 20.8 0.6 10.4 20.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Pex14_N PF04695.13 CDJ59449.1 - 0.49 11.0 16.4 0.72 10.5 16.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 CDJ59449.1 - 0.49 10.6 7.1 0.57 10.4 7.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RR_TM4-6 PF06459.12 CDJ59449.1 - 0.53 10.1 20.0 0.66 9.8 20.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OATP PF03137.20 CDJ59449.1 - 0.57 8.4 1.6 0.62 8.3 1.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.13 CDJ59449.1 - 0.62 9.8 5.9 0.65 9.7 5.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.6 CDJ59449.1 - 0.64 10.0 9.1 1 9.3 9.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 CDJ59449.1 - 0.66 10.0 9.4 0.85 9.7 9.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4045 PF13254.6 CDJ59449.1 - 0.77 9.3 13.4 0.85 9.2 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SID-1_RNA_chan PF13965.6 CDJ59449.1 - 0.9 7.9 4.5 1.1 7.6 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paf1 PF03985.13 CDJ59449.1 - 0.94 8.4 25.2 1.1 8.1 25.2 1.1 1 0 0 1 1 1 0 Paf1 Ndc1_Nup PF09531.10 CDJ59449.1 - 0.98 8.0 4.6 1 8.0 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 CDJ59449.1 - 1.1 8.1 13.9 1.3 8.0 13.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 CDJ59449.1 - 1.3 6.8 16.9 1.5 6.6 16.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ureide_permease PF07168.11 CDJ59449.1 - 1.3 7.7 6.7 1.4 7.6 6.7 1.1 1 0 0 1 1 1 0 Ureide permease Endostatin PF06482.11 CDJ59449.1 - 1.4 8.4 10.1 1.6 8.1 10.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Sin_N PF04801.13 CDJ59449.1 - 1.4 8.0 18.8 1.6 7.8 18.8 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region TERB2 PF15101.6 CDJ59449.1 - 1.5 8.8 13.5 1.8 8.6 13.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 CDJ59449.1 - 1.6 7.8 20.7 1.9 7.5 20.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_S64 PF08192.11 CDJ59449.1 - 1.6 7.1 9.8 1.6 7.1 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 BNIP2 PF12496.8 CDJ59449.1 - 1.7 9.1 16.3 2.4 8.6 16.3 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 AAA_11 PF13086.6 CDJ59449.1 - 1.8 8.3 12.4 2.2 8.0 12.4 1.1 1 0 0 1 1 1 0 AAA domain CLN3 PF02487.17 CDJ59449.1 - 1.8 7.5 7.7 2.2 7.2 7.7 1.2 1 0 0 1 1 1 0 CLN3 protein RP-C_C PF11800.8 CDJ59449.1 - 1.8 8.6 12.2 2.4 8.2 12.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PA26 PF04636.13 CDJ59449.1 - 2.1 7.2 9.2 2.2 7.1 9.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MAP17 PF15807.5 CDJ59449.1 - 2.5 8.3 10.0 3.4 7.9 10.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PPP4R2 PF09184.11 CDJ59449.1 - 2.7 7.5 21.3 4.7 6.7 21.3 1.4 1 0 0 1 1 1 0 PPP4R2 R_equi_Vir PF05526.11 CDJ59449.1 - 2.9 7.7 6.6 4.1 7.2 6.6 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein ASC PF00858.24 CDJ59449.1 - 3 6.7 7.5 3.6 6.4 7.5 1.0 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3245 PF11595.8 CDJ59449.1 - 3.2 8.2 30.2 1.2 9.6 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) DUF4484 PF14831.6 CDJ59449.1 - 3.4 7.6 15.3 4.5 7.3 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Serinc PF03348.15 CDJ59449.1 - 3.5 6.5 8.2 4.9 6.0 8.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ59449.1 - 3.5 6.5 15.1 4.2 6.3 15.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM163 PF15069.6 CDJ59449.1 - 3.8 7.9 9.6 2.9 8.3 8.5 1.4 1 1 0 1 1 1 0 FAM163 family Macoilin PF09726.9 CDJ59449.1 - 3.9 5.9 12.0 4.7 5.7 12.0 1.0 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 CDJ59449.1 - 4 6.1 13.6 4.5 5.9 13.6 1.0 1 0 0 1 1 1 0 Raftlin SAPS PF04499.15 CDJ59449.1 - 4.1 6.1 17.4 4.7 5.9 17.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Suf PF05843.14 CDJ59449.1 - 4.2 7.3 13.9 4.9 7.0 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 CDJ59449.1 - 4.6 4.2 10.1 4.9 4.1 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Folate_carrier PF01770.18 CDJ59449.1 - 4.9 5.8 5.1 5.4 5.7 5.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF5427 PF10310.9 CDJ59449.1 - 5.2 5.9 20.5 6.5 5.6 20.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hid1 PF12722.7 CDJ59449.1 - 5.6 5.0 15.9 6.4 4.8 15.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 CDJ59449.1 - 6.5 5.5 9.7 7.2 5.3 9.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2457 PF10446.9 CDJ59449.1 - 6.6 5.8 25.1 8.9 5.3 25.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zip PF02535.22 CDJ59449.1 - 8.2 5.5 13.9 9.6 5.3 13.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S25 PF03297.15 CDJ59456.1 - 0.47 10.7 2.9 0.75 10.0 0.1 2.4 3 0 0 3 3 3 0 S25 ribosomal protein Ldh_1_N PF00056.23 CDJ59457.1 - 1.6e-37 128.7 0.4 3e-37 127.9 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDJ59457.1 - 4.7e-29 101.5 0.0 6.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDJ59457.1 - 0.00014 21.5 0.8 0.0035 16.9 0.0 2.5 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 CDJ59457.1 - 0.071 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PGA2 PF07543.12 CDJ59459.1 - 0.0011 18.9 9.0 0.0014 18.6 9.0 1.3 1 0 0 1 1 1 1 Protein trafficking PGA2 MPP6 PF10175.9 CDJ59459.1 - 0.053 14.0 15.2 0.38 11.3 2.2 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 NOA36 PF06524.12 CDJ59459.1 - 0.39 10.0 13.6 0.49 9.7 13.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CDJ59459.1 - 1.2 9.6 18.3 0.32 11.4 8.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PPL5 PF18168.1 CDJ59459.1 - 1.5 8.0 8.7 1.7 7.9 8.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 FGF-BP1 PF06473.12 CDJ59459.1 - 1.8 8.4 7.3 2.1 8.1 7.3 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TLP-20 PF06088.11 CDJ59459.1 - 1.8 8.4 17.4 0.77 9.6 3.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NKAP PF15692.5 CDJ59459.1 - 1.8 9.3 22.4 4.4 8.1 3.6 2.1 2 0 0 2 2 2 0 NF-kappa-B-activating protein DUF4746 PF15928.5 CDJ59459.1 - 2.2 7.7 9.7 2.5 7.5 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIF_alpha PF05793.12 CDJ59459.1 - 3.2 6.2 26.3 4.1 5.9 26.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) V_ATPase_I PF01496.19 CDJ59459.1 - 4.6 5.0 5.2 5.1 4.9 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4611 PF15387.6 CDJ59459.1 - 4.6 7.5 24.2 7 7.0 7.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.13 CDJ59459.1 - 7.9 6.3 17.7 8.2 6.2 3.4 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region K_channel_TID PF07941.11 CDJ59460.1 - 0.00046 20.6 8.7 0.00046 20.6 8.7 7.9 6 2 2 8 8 8 2 Potassium channel Kv1.4 tandem inactivation domain SR-25 PF10500.9 CDJ59460.1 - 9 5.8 119.4 0.045 13.4 38.3 4.8 3 1 2 5 5 5 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpb2_6 PF00562.28 CDJ59462.1 - 9.9e-92 308.0 0.0 1.3e-91 307.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_4 PF04566.13 CDJ59462.1 - 5.5e-21 74.6 0.1 9.8e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CDJ59462.1 - 1.3e-16 60.9 2.5 2.8e-16 59.8 2.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SH2 PF00017.24 CDJ59462.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 SH2 domain DUF4231 PF14015.6 CDJ59463.1 - 0.73 10.3 0.0 0.73 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Med3 PF11593.8 CDJ59465.1 - 0.95 8.6 2.3 1.4 8.0 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DnaJ PF00226.31 CDJ59467.1 - 2.2e-14 53.3 0.8 3.4e-14 52.7 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CDJ59467.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin SR-25 PF10500.9 CDJ59468.1 - 4.6 6.8 12.5 7.3 6.1 12.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PARP PF00644.20 CDJ59472.1 - 1e-53 181.8 0.0 1.7e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDJ59472.1 - 1e-31 109.9 2.2 1.6e-31 109.2 2.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CDJ59472.1 - 1.3e-11 44.4 1.8 2.4e-11 43.5 0.9 2.0 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.12 CDJ59472.1 - 3.2e-11 42.8 0.1 3.2e-11 42.8 0.1 2.7 2 0 0 2 2 2 1 PADR1 (NUC008) domain BRCT PF00533.26 CDJ59472.1 - 1.1e-07 32.1 0.0 3.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.18 CDJ59472.1 - 2.1e-05 25.3 0.4 7.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PTCB-BRCT PF12738.7 CDJ59472.1 - 0.0072 16.3 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain Ribosomal_L27e PF01777.18 CDJ59473.1 - 9.2e-25 86.8 3.7 1.2e-24 86.5 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDJ59473.1 - 0.00078 19.3 1.7 0.0015 18.5 1.7 1.4 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.6 CDJ59473.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain DUF1294 PF06961.13 CDJ59474.1 - 0.072 13.3 0.4 0.21 11.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Endonuclease_NS PF01223.23 CDJ59477.1 - 1.5e-06 28.2 1.1 1.8e-06 27.9 1.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease RskA PF10099.9 CDJ59477.1 - 0.00033 21.0 3.7 0.00038 20.8 3.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3682 PF12446.8 CDJ59477.1 - 0.0032 18.0 19.6 0.0061 17.0 19.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) TFIIA PF03153.13 CDJ59477.1 - 0.0095 16.0 12.9 0.01 15.8 12.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ59477.1 - 0.038 13.5 2.4 0.037 13.5 2.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CDJ59477.1 - 0.047 12.5 3.5 0.049 12.4 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 CDJ59477.1 - 0.052 13.2 16.0 0.068 12.8 16.0 1.1 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 CDJ59477.1 - 0.089 12.6 4.5 0.099 12.5 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CDJ59477.1 - 0.2 10.4 4.1 0.19 10.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CDJ59477.1 - 0.21 11.0 2.2 0.2 11.0 2.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF_4EBP PF05456.11 CDJ59477.1 - 0.29 11.1 9.0 0.48 10.4 9.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Connexin PF00029.19 CDJ59477.1 - 0.35 10.6 1.0 0.37 10.5 1.0 1.1 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 CDJ59477.1 - 0.4 10.8 4.7 0.51 10.5 4.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Protamine_P2 PF00841.19 CDJ59477.1 - 0.5 10.9 7.1 0.81 10.2 7.1 1.3 1 0 0 1 1 1 0 Sperm histone P2 DUF1180 PF06679.12 CDJ59477.1 - 0.83 10.1 8.7 1.2 9.6 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4407 PF14362.6 CDJ59477.1 - 0.85 8.9 6.7 1.1 8.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 CDJ59477.1 - 1.1 8.5 13.5 1.7 8.0 13.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 CDJ59477.1 - 1.3 8.0 11.1 1.6 7.6 11.1 1.1 1 0 0 1 1 1 0 Paf1 DUF5421 PF17458.2 CDJ59477.1 - 2.6 7.4 13.6 3.6 6.9 13.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) THOC2_N PF16134.5 CDJ59477.1 - 3.4 6.2 8.0 4 5.9 8.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4834 PF16118.5 CDJ59477.1 - 6 7.9 10.5 8.9 7.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RskA PF10099.9 CDJ59478.1 - 0.0016 18.8 15.8 0.0016 18.8 15.8 13.5 2 1 9 12 12 12 5 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ59479.1 - 0.0065 16.1 1.7 0.0065 16.1 1.7 10.3 7 3 1 9 9 9 3 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ59479.1 - 0.0068 17.0 0.2 0.0068 17.0 0.2 11.6 4 3 5 9 9 9 1 Dehydrin DUF4179 PF13786.6 CDJ59479.1 - 5.2 7.6 19.9 12 6.5 0.1 6.6 6 1 0 6 6 6 0 Domain of unknown function (DUF4179) Oxidored_q6 PF01058.22 CDJ59480.1 - 0.26 11.1 3.9 0.09 12.6 0.4 2.1 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit ubiquitin PF00240.23 CDJ59481.1 - 3.2e-09 36.4 0.0 1.4e-08 34.4 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDJ59481.1 - 4.1e-06 26.6 0.2 4.1e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Macoilin PF09726.9 CDJ59481.1 - 4.6 5.7 39.1 0.017 13.7 28.2 2.0 2 0 0 2 2 2 0 Macoilin family SR-25 PF10500.9 CDJ59481.1 - 8.9 5.9 43.5 0.22 11.1 26.1 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SWIB PF02201.18 CDJ59482.1 - 5.2e-23 80.7 0.1 8e-23 80.1 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain RCC1 PF00415.18 CDJ59483.1 - 1.1e-24 86.8 11.5 8.4e-09 35.9 0.1 5.4 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Myosin_head PF00063.21 CDJ59483.1 - 1.6e-20 72.9 0.0 3.7e-17 61.8 0.0 2.9 2 1 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 CDJ59483.1 - 1.4e-09 36.9 31.7 0.062 13.1 2.0 7.9 7 0 0 7 7 7 4 IQ calmodulin-binding motif RCC1_2 PF13540.6 CDJ59483.1 - 1.6e-09 37.3 20.5 2.7e-08 33.4 0.4 5.4 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Mannosyl_trans PF05007.13 CDJ59484.1 - 1.2e-38 133.5 8.7 1.1e-37 130.4 8.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF1045 PF06299.12 CDJ59484.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) BTB PF00651.31 CDJ59485.1 - 2.1e-05 24.7 0.1 7.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain FPL PF09758.9 CDJ59486.1 - 3e-57 192.8 3.7 5.1e-57 192.0 3.7 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein MRG PF05712.13 CDJ59486.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 MRG DUF2357 PF09823.9 CDJ59486.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF4200 PF13863.6 CDJ59488.1 - 0.00028 21.3 15.5 0.00028 21.3 15.5 4.9 2 1 2 5 5 5 1 Domain of unknown function (DUF4200) MarR_2 PF12802.7 CDJ59493.1 - 0.014 15.3 0.8 0.93 9.4 0.0 3.7 4 0 0 4 4 4 0 MarR family Cofac_haem_bdg PF04187.13 CDJ59495.1 - 0.03 14.3 0.5 0.055 13.5 0.5 1.4 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN NopRA1 PF16201.5 CDJ59498.1 - 3.2e-05 23.6 1.1 0.00012 21.7 1.1 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 ISP1_C PF18161.1 CDJ59499.1 - 1.2e-38 131.4 0.0 1.6e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal ISP3_C PF18045.1 CDJ59499.1 - 7.5e-37 125.6 0.0 9.4e-37 125.3 0.0 1.1 1 0 0 1 1 1 1 ISP3 C-terminal RskA PF10099.9 CDJ59501.1 - 0.0084 16.4 4.6 0.0084 16.4 4.6 11.2 4 4 3 9 9 9 3 Anti-sigma-K factor rskA Photo_RC PF00124.19 CDJ59501.1 - 0.064 12.5 0.0 0.2 10.9 0.0 1.8 1 0 0 1 1 1 0 Photosynthetic reaction centre protein DUF2434 PF10361.9 CDJ59501.1 - 0.22 10.5 1.3 0.48 9.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) UPF0565 PF10561.9 CDJ59502.1 - 8.5e-05 21.9 0.9 0.0015 17.8 0.7 2.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0565 eIF3_subunit PF08597.10 CDJ59502.1 - 0.00028 20.9 10.3 0.00076 19.5 10.3 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CAF1 PF04857.20 CDJ59502.1 - 0.0011 18.2 3.9 0.0017 17.6 3.9 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease TMEM51 PF15345.6 CDJ59502.1 - 0.0015 18.5 14.5 0.0015 18.5 14.5 2.3 3 0 0 3 3 2 1 Transmembrane protein 51 GPCR_chapero_1 PF11904.8 CDJ59502.1 - 0.0095 15.4 9.6 0.012 15.1 8.0 1.9 2 0 0 2 2 2 1 GPCR-chaperone DUF4746 PF15928.5 CDJ59502.1 - 0.0099 15.3 8.3 0.016 14.6 8.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) MDM10 PF12519.8 CDJ59502.1 - 0.011 14.7 10.5 0.019 13.9 10.5 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 CDJ59502.1 - 0.024 13.5 1.3 0.045 12.6 1.3 1.6 1 0 0 1 1 1 0 Otopetrin Apt1 PF10351.9 CDJ59502.1 - 0.024 13.5 15.8 0.17 10.7 9.3 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ59502.1 - 0.031 12.6 16.4 0.011 14.1 13.2 1.8 2 0 0 2 2 2 0 CDC45-like protein SID-1_RNA_chan PF13965.6 CDJ59502.1 - 0.034 12.6 2.4 0.055 11.9 2.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.12 CDJ59502.1 - 0.039 12.9 23.4 0.076 12.0 23.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S64 PF08192.11 CDJ59502.1 - 0.089 11.3 16.6 0.13 10.8 12.1 2.2 2 0 0 2 2 2 0 Peptidase family S64 Serinc PF03348.15 CDJ59502.1 - 0.27 10.1 5.5 0.43 9.5 5.5 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ59502.1 - 0.64 9.0 21.3 1.4 7.8 21.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Glyco_transf_41 PF13844.6 CDJ59502.1 - 0.74 8.2 4.6 1.1 7.6 4.6 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 PPL5 PF18168.1 CDJ59502.1 - 4 6.7 14.9 2.4 7.4 12.3 1.9 2 0 0 2 2 2 0 Prim-pol family 5 TAF4 PF05236.14 CDJ59502.1 - 4.4 7.0 26.0 0.2 11.4 8.1 3.7 4 0 0 4 4 4 0 Transcription initiation factor TFIID component TAF4 family PPP4R2 PF09184.11 CDJ59502.1 - 5.2 6.6 17.4 0.012 15.2 4.9 2.5 2 1 0 2 2 2 0 PPP4R2 RR_TM4-6 PF06459.12 CDJ59502.1 - 7.2 6.3 29.4 22 4.8 29.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 CDJ59502.1 - 7.8 6.5 17.4 16 5.4 17.4 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pex14_N PF04695.13 CDJ59502.1 - 7.9 7.1 53.2 11 6.6 37.5 4.5 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3959 PF13105.6 CDJ59503.1 - 0.31 10.5 0.0 0.31 10.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3959) Topoisom_bac PF01131.20 CDJ59504.1 - 8.3e-33 114.0 0.0 8.7e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase DnaJ PF00226.31 CDJ59505.1 - 2.3e-16 59.7 2.6 3.8e-16 59.0 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain Macoilin PF09726.9 CDJ59505.1 - 0.00067 18.4 30.0 0.00088 18.0 30.0 1.1 1 0 0 1 1 1 1 Macoilin family SOG2 PF10428.9 CDJ59505.1 - 0.03 13.5 36.0 0.035 13.3 36.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 CDJ59505.1 - 0.041 12.5 19.6 0.044 12.4 19.6 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1387 PF07139.11 CDJ59505.1 - 0.2 11.4 21.3 0.27 10.9 21.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ndc1_Nup PF09531.10 CDJ59505.1 - 0.68 8.6 18.2 0.88 8.2 18.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 CDJ59505.1 - 2.5 6.8 13.2 3.1 6.5 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF572 PF04502.13 CDJ59505.1 - 3.3 7.2 21.2 3.9 7.0 21.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.9 CDJ59506.1 - 0.0026 17.4 10.2 0.0026 17.4 10.2 3.1 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 CDJ59506.1 - 0.0052 17.3 15.2 0.0052 17.3 15.2 7.5 5 2 2 7 7 7 1 60s Acidic ribosomal protein DUF1635 PF07795.11 CDJ59506.1 - 0.0084 16.0 1.9 0.0084 16.0 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) Secretin_N_2 PF07655.13 CDJ59506.1 - 0.019 15.5 10.7 0.019 15.5 10.7 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain BRCT_2 PF16589.5 CDJ59506.1 - 0.062 13.7 0.2 0.16 12.4 0.2 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AF-4 PF05110.13 CDJ59506.1 - 0.62 8.1 26.3 0.44 8.6 11.6 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ59506.1 - 1 8.9 35.1 0.93 9.1 26.1 2.5 2 0 0 2 2 2 0 Spt20 family Chorion_2 PF03964.15 CDJ59507.1 - 4.5 8.2 10.7 1.1 10.1 3.1 2.4 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.8 CDJ59507.1 - 8.2 6.8 25.6 6.9 7.0 10.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Slu7 PF11708.8 CDJ59509.1 - 0.0083 15.9 5.5 0.0083 15.9 5.5 1.8 1 1 1 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor TFIIA PF03153.13 CDJ59509.1 - 0.011 15.8 23.9 0.014 15.4 23.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M28 PF04389.17 CDJ59509.1 - 0.12 12.0 4.7 0.082 12.6 2.0 1.9 1 1 1 2 2 2 0 Peptidase family M28 Ndc1_Nup PF09531.10 CDJ59509.1 - 0.35 9.5 12.0 0.39 9.4 12.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 CDJ59509.1 - 2.3 7.9 12.9 2.3 7.9 11.8 1.6 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ59509.1 - 3.3 6.4 13.4 4.7 5.9 13.4 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ59509.1 - 3.4 6.4 9.5 4.6 5.9 9.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ59509.1 - 9.6 5.1 15.8 13 4.7 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 BUD22 PF09073.10 CDJ59510.1 - 0.0023 17.3 17.1 0.0023 17.3 17.1 3.3 2 1 1 3 3 3 2 BUD22 Band_3_cyto PF07565.13 CDJ59510.1 - 0.0095 15.8 11.1 0.0095 15.8 11.1 3.7 3 1 0 3 3 3 1 Band 3 cytoplasmic domain Caldesmon PF02029.15 CDJ59510.1 - 0.01 14.6 60.6 0.13 11.0 8.1 2.2 2 0 0 2 2 2 0 Caldesmon Calici_MSP PF05752.11 CDJ59511.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF2817 PF10994.8 CDJ59511.1 - 0.094 12.1 0.8 0.13 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) WXG100 PF06013.12 CDJ59512.1 - 0.11 12.7 1.6 0.31 11.3 1.6 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF3947 PF13135.6 CDJ59513.1 - 0.053 13.7 2.9 0.12 12.6 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TFIIF_alpha PF05793.12 CDJ59515.1 - 0.0011 17.7 16.3 0.0011 17.7 16.3 1.9 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Torus PF16131.5 CDJ59515.1 - 0.0058 17.3 0.2 0.0058 17.3 0.2 3.9 4 0 0 4 4 4 1 Torus domain zf-CCCH PF00642.24 CDJ59515.1 - 0.026 14.5 6.0 0.029 14.3 4.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ59515.1 - 1.2 9.3 5.3 2.5 8.3 5.3 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CDJ59515.1 - 2.8 8.5 5.3 5.3 7.7 5.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CTP_transf_like PF01467.26 CDJ59516.1 - 7.3e-32 110.5 0.2 1.2e-31 109.8 0.2 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like LPP PF04728.13 CDJ59517.1 - 0.013 15.8 4.9 0.013 15.8 4.9 3.7 3 1 1 4 4 3 0 Lipoprotein leucine-zipper HALZ PF02183.18 CDJ59517.1 - 0.067 13.4 0.1 0.067 13.4 0.1 4.4 4 1 0 4 4 4 0 Homeobox associated leucine zipper ATG16 PF08614.11 CDJ59517.1 - 0.11 12.8 46.6 0.48 10.6 8.8 3.7 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 CDJ59517.1 - 0.16 10.8 10.3 1 8.2 2.4 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein IFT57 PF10498.9 CDJ59517.1 - 0.21 10.5 18.2 0.23 10.4 8.9 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF812 PF05667.11 CDJ59517.1 - 0.39 9.5 32.3 0.061 12.2 12.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) OmpH PF03938.14 CDJ59517.1 - 0.4 11.0 27.5 1.2 9.5 13.6 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Rootletin PF15035.6 CDJ59517.1 - 0.89 9.6 25.4 0.067 13.2 1.5 3.5 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 CDJ59517.1 - 1 8.9 43.4 1.5 8.4 21.3 4.2 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease FliD_C PF07195.12 CDJ59517.1 - 1.1 8.6 8.9 12 5.3 5.0 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Leu_zip PF15294.6 CDJ59517.1 - 1.4 8.4 32.1 0.97 8.9 11.1 2.6 2 1 0 2 2 2 0 Leucine zipper FapA PF03961.13 CDJ59517.1 - 1.7 7.2 22.4 0.0066 15.1 5.6 2.6 2 1 1 3 3 3 0 Flagellar Assembly Protein A MMPL PF03176.15 CDJ59517.1 - 2 7.3 5.8 3.4 6.5 5.8 1.3 1 0 0 1 1 1 0 MMPL family Phage_GPO PF05929.11 CDJ59517.1 - 2.5 7.6 20.0 0.97 9.0 0.1 2.6 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.13 CDJ59517.1 - 2.6 7.2 21.5 0.0092 15.3 5.7 2.7 3 0 0 3 3 3 0 TMPIT-like protein Fez1 PF06818.15 CDJ59517.1 - 3.8 7.9 29.0 6.2 7.2 10.9 2.6 2 0 0 2 2 2 0 Fez1 Atg14 PF10186.9 CDJ59517.1 - 6.6 5.7 29.0 0.85 8.6 10.5 3.1 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 CDJ59517.1 - 6.6 6.5 36.5 4 7.2 9.9 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH KH_1 PF00013.29 CDJ59518.1 - 9.2e-23 79.9 0.0 5.5e-07 29.3 0.0 6.3 6 0 0 6 6 6 4 KH domain Secretin_N PF03958.17 CDJ59518.1 - 5.8e-07 29.8 5.2 0.032 14.6 0.1 5.3 4 0 0 4 4 4 3 Bacterial type II/III secretion system short domain KH_2 PF07650.17 CDJ59518.1 - 0.0024 17.6 1.3 7.1 6.5 0.0 4.0 3 0 0 3 3 3 2 KH domain BMC PF00936.19 CDJ59518.1 - 0.0078 16.2 0.2 3.2 7.8 0.0 4.4 4 0 0 4 4 4 1 BMC domain Dodecin PF07311.12 CDJ59518.1 - 0.46 10.8 2.2 8.5 6.7 0.0 3.9 4 0 0 4 4 4 0 Dodecin TF_Zn_Ribbon PF08271.12 CDJ59519.1 - 2.6e-08 33.2 3.7 5e-08 32.3 3.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 CDJ59519.1 - 1.5e-06 28.2 0.1 5.9e-06 26.2 0.1 2.1 1 0 0 1 1 1 1 Transcription factor TFIIB repeat BRF1 PF07741.13 CDJ59519.1 - 0.00031 21.1 1.4 0.0015 18.9 0.7 3.8 3 1 1 4 4 4 2 Brf1-like TBP-binding domain DUF4503 PF14951.6 CDJ59519.1 - 0.09 11.2 0.9 0.13 10.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) A2L_zn_ribbon PF08792.10 CDJ59519.1 - 0.24 11.2 1.2 0.5 10.2 1.2 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Rgp1 PF08737.10 CDJ59520.1 - 0.96 8.5 29.5 1.3 8.1 16.3 2.6 2 0 0 2 2 2 0 Rgp1 RR_TM4-6 PF06459.12 CDJ59520.1 - 5.3 6.8 34.7 0.62 9.8 17.8 3.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 CDJ59520.1 - 8.6 5.5 17.3 0.69 9.1 8.2 2.8 2 0 0 2 2 2 0 ZIP Zinc transporter CLN3 PF02487.17 CDJ59520.1 - 9.8 5.1 23.8 0.4 9.7 10.9 2.9 2 0 0 2 2 2 0 CLN3 protein Tub_N PF16322.5 CDJ59521.1 - 0.0073 16.7 0.9 0.0073 16.7 0.9 2.2 2 0 0 2 2 2 1 Tubby N-terminal Spt20 PF12090.8 CDJ59521.1 - 0.42 10.2 7.8 0.83 9.2 7.8 1.4 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 CDJ59522.1 - 3.1e-07 30.1 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.28 CDJ59523.1 - 1.3e-24 87.0 0.0 1.1e-23 84.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDJ59523.1 - 1.3e-05 25.1 0.1 9.7e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 CDJ59523.1 - 6.9e-05 22.1 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 CDJ59523.1 - 0.00074 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.19 CDJ59523.1 - 0.0052 16.1 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 CDJ59523.1 - 0.0074 16.4 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CDJ59523.1 - 0.05 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 CDJ59523.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NICE-1 PF15845.5 CDJ59524.1 - 0.024 15.4 1.5 0.024 15.4 1.5 10.5 5 3 5 10 10 10 0 Cysteine-rich C-terminal 1 family ABC_membrane PF00664.23 CDJ59525.1 - 4.8e-18 65.8 0.5 5.8e-18 65.5 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF478 PF04334.12 CDJ59525.1 - 0.053 13.6 0.6 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF478) RseC_MucC PF04246.12 CDJ59525.1 - 0.083 12.8 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Thioredoxin_7 PF13899.6 CDJ59526.1 - 9.3e-09 35.4 0.7 1.8e-08 34.5 0.7 1.4 1 0 0 1 1 1 1 Thioredoxin-like adh_short PF00106.25 CDJ59529.1 - 1.7e-29 102.7 3.3 1.8e-18 66.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ59529.1 - 4e-13 49.5 3.0 7.7e-08 32.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ59529.1 - 1.7e-08 34.6 3.2 3.7e-07 30.2 0.7 2.3 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 CDJ59529.1 - 0.00066 19.2 0.2 0.025 14.0 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 CDJ59529.1 - 0.0039 17.1 0.3 0.0094 15.9 0.2 1.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus DFP PF04127.15 CDJ59529.1 - 0.0061 16.4 4.0 0.03 14.2 3.4 2.3 1 1 2 3 3 3 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 CDJ59529.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 CDJ59529.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CDJ59529.1 - 0.069 13.0 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H-binding ExoD PF06055.12 CDJ59529.1 - 0.14 11.5 3.3 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD LRR_8 PF13855.6 CDJ59530.1 - 1.2e-08 34.6 0.8 0.00016 21.3 0.0 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ59530.1 - 3.7e-06 27.2 3.5 0.19 12.2 0.0 5.1 2 1 4 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDJ59530.1 - 0.0014 18.5 1.9 9.5 6.6 0.0 5.6 7 0 0 7 7 7 1 Leucine Rich repeat Phage_T7_Capsid PF05396.11 CDJ59531.1 - 0.026 14.9 0.0 0.093 13.1 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein TSP_1 PF00090.19 CDJ59532.1 - 0.0073 16.5 6.2 0.016 15.4 5.1 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain Myosin_head PF00063.21 CDJ59533.1 - 3.3e-35 121.5 0.4 2.5e-19 69.0 0.0 2.5 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_head PF00063.21 CDJ59534.1 - 2.3e-10 39.4 0.0 3.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) FlaG PF03646.15 CDJ59535.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 FlaG protein MFAP1 PF06991.11 CDJ59537.1 - 2.4e-10 40.6 22.1 2.4e-10 40.6 22.1 2.6 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing SUIM_assoc PF16619.5 CDJ59537.1 - 0.12 12.4 46.1 0.31 11.2 8.4 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Hamartin PF04388.12 CDJ59537.1 - 1.5 7.4 21.3 1.8 7.1 21.3 1.0 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 CDJ59537.1 - 1.6 6.9 28.2 1.9 6.7 28.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.6 CDJ59537.1 - 1.7 9.2 15.4 2.2 8.8 15.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TYW3 PF02676.14 CDJ59537.1 - 6.9 6.0 10.7 16 4.8 10.5 1.8 1 1 0 1 1 1 0 Methyltransferase TYW3 Sipho_Gp157 PF05565.11 CDJ59538.1 - 0.0077 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Siphovirus Gp157 LST1 PF05083.13 CDJ59538.1 - 0.024 14.9 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 LST-1 protein Troponin PF00992.20 CDJ59538.1 - 0.042 14.2 0.2 0.064 13.6 0.2 1.2 1 0 0 1 1 1 0 Troponin GreA_GreB_N PF03449.15 CDJ59538.1 - 0.061 13.5 0.6 0.11 12.6 0.6 1.4 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal TMF_DNA_bd PF12329.8 CDJ59538.1 - 0.091 12.8 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 CDJ59538.1 - 0.24 10.8 1.1 0.35 10.3 1.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PhoLip_ATPase_C PF16212.5 CDJ59541.1 - 2.6e-38 132.2 8.5 2.9e-37 128.8 4.5 2.2 2 0 0 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 CDJ59541.1 - 1.4e-08 34.7 0.2 2.1e-07 30.9 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDJ59541.1 - 1.9e-08 34.9 10.9 0.0001 22.7 5.6 4.2 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ59541.1 - 0.015 15.0 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1700 PF08006.11 CDJ59541.1 - 0.17 11.4 0.1 0.4 10.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Tma16 PF11176.8 CDJ59541.1 - 1.9 8.3 10.3 0.021 14.7 2.0 2.0 2 0 0 2 2 2 0 Translation machinery-associated protein 16 Las1 PF04031.13 CDJ59543.1 - 1.7e-37 128.9 0.1 1.7e-37 128.9 0.1 5.1 4 1 0 4 4 4 1 Las1-like WW PF00397.26 CDJ59544.1 - 2.8e-09 36.9 2.3 4.9e-09 36.1 2.3 1.4 1 0 0 1 1 1 1 WW domain Yip1 PF04893.17 CDJ59544.1 - 3.5e-06 26.8 8.1 1.1e-05 25.3 8.2 1.8 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 CDJ59544.1 - 0.091 12.3 0.1 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 YIF1 Glyco_hydro_100 PF12899.7 CDJ59544.1 - 0.097 11.3 0.9 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase Caldesmon PF02029.15 CDJ59546.1 - 0.00025 20.0 24.5 0.00025 20.0 24.5 2.2 1 1 1 2 2 2 1 Caldesmon CENP-N PF05238.13 CDJ59546.1 - 4 6.6 28.2 1.4 8.1 18.4 2.5 2 0 0 2 2 2 0 Kinetochore protein CHL4 like PIP5K PF01504.18 CDJ59547.1 - 3.2e-78 262.7 0.0 3.9e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA_lid_9 PF17871.1 CDJ59549.1 - 2.1e-23 82.2 2.4 4.2e-23 81.2 2.4 1.5 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CDJ59549.1 - 2.1e-12 47.6 0.1 5.7e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ59549.1 - 1.7e-11 44.8 0.6 2.7e-10 40.9 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain TniB PF05621.11 CDJ59549.1 - 9.8e-07 28.4 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein ATPase_2 PF01637.18 CDJ59549.1 - 1.8e-06 28.0 0.4 0.061 13.2 0.0 2.7 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDJ59549.1 - 1.9e-06 28.2 0.9 6.4e-05 23.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CDJ59549.1 - 0.00089 19.0 0.6 0.68 9.7 0.1 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDJ59549.1 - 0.0011 19.0 0.2 0.0075 16.3 0.1 2.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDJ59549.1 - 0.0012 18.4 0.1 0.18 11.3 0.0 2.5 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 CDJ59549.1 - 0.0015 18.9 0.1 0.0036 17.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain MutS_V PF00488.21 CDJ59549.1 - 0.002 18.2 0.6 0.45 10.5 0.1 2.3 2 0 0 2 2 2 1 MutS domain V TsaE PF02367.17 CDJ59549.1 - 0.0044 17.0 0.1 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CDJ59549.1 - 0.0064 16.4 0.2 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 CDJ59549.1 - 0.0073 15.5 0.5 0.024 13.8 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 CDJ59549.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Herpes_UL69 PF05459.12 CDJ59549.1 - 0.013 14.8 0.5 0.029 13.7 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family MMR_HSR1 PF01926.23 CDJ59549.1 - 0.024 14.7 0.0 0.073 13.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CDJ59549.1 - 0.03 14.9 0.5 0.4 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ligase_CoA PF00549.19 CDJ59549.1 - 0.032 14.0 0.1 0.095 12.5 0.1 1.8 1 0 0 1 1 1 0 CoA-ligase DUF815 PF05673.13 CDJ59549.1 - 0.053 12.7 0.2 1.4 8.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CDJ59549.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CDJ59549.1 - 0.12 11.7 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2396 PF09654.10 CDJ59551.1 - 0.11 12.5 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) TPKR_C2 PF16920.5 CDJ59551.1 - 0.71 10.1 0.0 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 Tyrosine-protein kinase receptor C2 Ig-like domain DNA_primase_S PF01896.19 CDJ59552.1 - 0.15 12.1 1.4 0.27 11.3 1.4 1.6 1 1 0 1 1 1 0 DNA primase small subunit SseC PF04888.12 CDJ59552.1 - 0.97 9.0 19.4 1.2 8.7 14.2 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ZYG-11_interact PF05884.12 CDJ59552.1 - 1.7 8.0 4.7 2.9 7.2 4.7 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 ELFV_dehydrog PF00208.21 CDJ59553.1 - 8.1e-20 71.6 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Nicastrin PF05450.15 CDJ59556.1 - 0.055 12.9 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Nicastrin Serpin PF00079.20 CDJ59557.1 - 1.5e-77 261.4 0.1 1.8e-77 261.1 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Methyltransf_3 PF01596.17 CDJ59558.1 - 0.052 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PRMT5_C PF17286.2 CDJ59558.1 - 0.07 13.0 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 PRMT5 oligomerisation domain PrmA PF06325.13 CDJ59558.1 - 0.15 11.4 0.2 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CDJ59558.1 - 0.21 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S8 PF00082.22 CDJ59559.1 - 7.4e-23 81.3 1.0 2.4e-17 63.1 0.0 2.1 1 1 1 2 2 2 2 Subtilase family AP2 PF00847.20 CDJ59560.1 - 0.00025 21.2 1.5 0.00076 19.7 1.5 1.9 1 0 0 1 1 1 1 AP2 domain TPR_1 PF00515.28 CDJ59561.1 - 2.5e-45 150.5 29.6 3.2e-10 39.4 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ59561.1 - 2.6e-37 123.9 26.3 3.9e-08 32.8 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ59561.1 - 1.1e-23 82.7 13.9 3e-09 36.4 1.9 5.4 4 1 1 5 5 5 4 TPR repeat TPR_12 PF13424.6 CDJ59561.1 - 6.5e-21 74.4 7.4 1.9e-12 47.3 0.6 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ59561.1 - 3.6e-20 70.4 23.9 4.8e-05 23.2 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ59561.1 - 5.2e-19 68.6 2.9 8.9e-05 23.1 0.5 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ59561.1 - 1e-16 60.2 4.7 0.0053 17.5 0.3 6.4 3 2 3 6 6 6 3 Tetratricopeptide repeat STI1 PF17830.1 CDJ59561.1 - 1.3e-14 53.8 4.4 4.3e-14 52.2 4.0 2.2 2 0 0 2 2 1 1 STI1 domain TPR_7 PF13176.6 CDJ59561.1 - 1.6e-13 49.6 6.3 9.5e-05 22.2 0.2 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ59561.1 - 3.8e-13 49.4 0.2 0.0018 18.4 0.0 4.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ59561.1 - 1.5e-12 46.9 11.0 0.08 12.8 0.3 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ59561.1 - 4.6e-12 46.3 11.5 0.0011 19.5 1.7 4.5 1 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ59561.1 - 1.7e-11 43.6 19.9 0.013 15.9 0.6 6.2 7 0 0 7 7 6 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDJ59561.1 - 4.7e-07 29.8 9.7 0.58 10.3 0.0 5.5 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CDJ59561.1 - 7.2e-06 26.3 13.3 0.27 12.0 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ59561.1 - 6.4e-05 23.1 16.5 0.039 14.2 2.1 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 CDJ59561.1 - 0.043 12.8 4.5 0.8 8.6 1.3 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) RNase_PH_C PF03725.15 CDJ59561.1 - 0.05 13.6 0.8 0.62 10.1 0.2 2.8 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 MIT PF04212.18 CDJ59561.1 - 0.15 12.1 14.1 5.6 7.1 0.8 4.8 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 CDJ59561.1 - 0.15 12.3 7.5 0.84 10.0 0.2 3.6 4 0 0 4 4 2 0 PPR repeat Chlamy_scaf PF09675.10 CDJ59561.1 - 0.22 11.9 3.0 5.8 7.3 0.0 3.6 3 1 1 4 4 3 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) DnaI_N PF07319.11 CDJ59561.1 - 0.26 12.0 8.0 0.17 12.5 1.1 3.4 2 1 0 3 3 3 0 Primosomal protein DnaI N-terminus DUF5113 PF17140.4 CDJ59561.1 - 0.28 11.0 9.8 0.24 11.2 4.7 3.0 2 2 3 5 5 5 0 Domain of unknown function (DUF5113) PPR_2 PF13041.6 CDJ59561.1 - 0.81 9.9 4.6 21 5.4 0.2 3.2 3 0 0 3 3 2 0 PPR repeat family DUF3391 PF11871.8 CDJ59561.1 - 1.1 9.7 11.5 1.7 9.2 2.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) ABA_GPCR PF12430.8 CDJ59562.1 - 2.5e-32 112.1 11.8 4e-32 111.4 11.8 1.3 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CDJ59562.1 - 6.1e-18 64.7 1.8 1.3e-16 60.5 0.0 2.7 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Spt20 PF12090.8 CDJ59562.1 - 0.002 17.8 7.6 0.003 17.2 7.6 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ59562.1 - 0.0052 16.8 3.3 0.0064 16.5 3.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ59562.1 - 0.01 14.9 5.4 0.014 14.4 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ59562.1 - 0.034 12.9 8.8 0.046 12.4 8.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.9 CDJ59562.1 - 0.31 10.6 13.2 0.58 9.7 13.3 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4175 PF13779.6 CDJ59562.1 - 0.68 7.8 8.3 1.1 7.1 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.8 CDJ59562.1 - 5.7 6.0 11.9 9 5.4 11.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4333 PF14230.6 CDJ59563.1 - 0.43 10.8 4.7 1.3 9.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) SR-25 PF10500.9 CDJ59563.1 - 2.4 7.7 34.1 0.4 10.3 19.7 2.4 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CDJ59563.1 - 8.9 6.8 30.7 0.12 12.9 8.4 3.4 1 1 2 3 3 3 0 Dehydrin DSBA PF01323.20 CDJ59564.1 - 0.079 12.7 0.3 0.089 12.6 0.3 1.0 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Hydrolase_4 PF12146.8 CDJ59565.1 - 2.9e-07 30.0 0.4 2.9e-07 30.0 0.4 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Spt20 PF12090.8 CDJ59565.1 - 0.0007 19.3 63.7 0.063 12.9 5.5 4.2 4 0 0 4 4 4 4 Spt20 family TFIIA PF03153.13 CDJ59565.1 - 3 7.7 63.0 0.047 13.7 9.1 3.5 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ59566.1 - 4.3e-05 23.3 7.6 0.00038 20.2 0.5 2.5 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis WD40 PF00400.32 CDJ59566.1 - 7.1e-05 23.5 3.5 0.5 11.3 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat SUIM_assoc PF16619.5 CDJ59566.1 - 0.00019 21.4 54.4 0.014 15.5 0.3 6.6 6 0 0 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ59566.1 - 0.00023 21.3 4.4 0.00023 21.3 4.4 3.1 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 CDJ59566.1 - 0.053 13.3 1.4 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Connexin Ge1_WD40 PF16529.5 CDJ59566.1 - 0.059 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tmemb_9 PF05434.11 CDJ59566.1 - 0.068 13.1 0.2 0.068 13.1 0.2 3.0 3 0 0 3 3 3 0 TMEM9 Glycophorin_A PF01102.18 CDJ59566.1 - 0.091 13.0 0.2 0.091 13.0 0.2 2.5 3 1 1 4 4 4 0 Glycophorin A TMEM154 PF15102.6 CDJ59566.1 - 0.11 12.4 1.6 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 TMEM154 protein family EOS1 PF12326.8 CDJ59566.1 - 0.12 12.3 0.3 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 N-glycosylation protein Peptidase_S49_N PF08496.10 CDJ59566.1 - 0.13 12.3 0.7 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1180 PF06679.12 CDJ59566.1 - 0.14 12.6 0.1 0.14 12.6 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) Coilin_N PF15862.5 CDJ59566.1 - 1.5 8.6 9.6 0.36 10.6 0.1 2.8 3 0 0 3 3 3 0 Coilin N-terminus DUF966 PF06136.13 CDJ59566.1 - 2.3 7.8 10.1 0.43 10.3 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FAM176 PF14851.6 CDJ59566.1 - 3.7 7.2 6.5 0.39 10.4 0.5 2.4 3 0 0 3 3 3 0 FAM176 family Serinc PF03348.15 CDJ59566.1 - 7.8 5.3 11.8 0.2 10.5 2.0 2.7 2 1 1 3 3 3 0 Serine incorporator (Serinc) BAF1_ABF1 PF04684.13 CDJ59567.1 - 0.0029 16.7 4.6 0.0029 16.7 4.6 7.4 3 1 2 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor Gemini_mov PF01708.16 CDJ59567.1 - 0.034 13.9 4.0 2.5 7.9 0.4 4.7 2 0 0 2 2 2 0 Geminivirus putative movement protein GBV-C_env PF12786.7 CDJ59567.1 - 2.1 7.0 4.0 4.1 6.0 4.0 1.4 1 0 0 1 1 1 0 GB virus C genotype envelope Syndecan PF01034.20 CDJ59567.1 - 2.3 8.2 3.8 9.8 6.2 3.8 2.1 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 CDJ59567.1 - 4.2 6.0 6.0 1.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BTB PF00651.31 CDJ59568.1 - 1.4e-09 38.2 1.1 7.4e-09 35.8 1.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF4207 PF13904.6 CDJ59568.1 - 0.0014 18.4 1.9 0.0014 18.4 1.9 8.8 5 2 2 7 7 7 2 Domain of unknown function (DUF4207) Spt20 PF12090.8 CDJ59568.1 - 0.0039 16.9 13.4 0.0039 16.9 13.4 9.8 5 3 2 7 7 7 2 Spt20 family zf-CDGSH PF09360.10 CDJ59569.1 - 5.8e-11 42.4 0.1 2e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF4667 PF15700.5 CDJ59569.1 - 5.1e-06 26.8 8.4 5.6e-06 26.6 8.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Lin-8 PF03353.15 CDJ59569.1 - 0.0086 15.7 2.8 0.0087 15.7 2.8 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF1645 PF07816.11 CDJ59569.1 - 0.023 15.3 7.6 0.029 15.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ59569.1 - 0.025 14.2 10.1 0.036 13.7 10.1 1.1 1 0 0 1 1 1 0 Spt20 family AF-4 PF05110.13 CDJ59569.1 - 0.052 11.6 15.5 0.068 11.3 15.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FANCM-MHF_bd PF16783.5 CDJ59569.1 - 0.057 13.5 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 FANCM to MHF binding domain Apt1 PF10351.9 CDJ59569.1 - 0.1 11.4 5.5 0.1 11.4 5.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ59569.1 - 0.29 9.6 10.5 0.36 9.3 10.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4718 PF15842.5 CDJ59569.1 - 0.33 10.7 9.3 0.45 10.3 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Herpes_capsid PF06112.11 CDJ59569.1 - 0.48 10.5 13.0 0.62 10.1 13.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GREB1 PF15782.5 CDJ59569.1 - 0.49 7.5 6.5 0.45 7.6 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ59569.1 - 3 6.5 5.7 3.6 6.3 5.7 1.1 1 0 0 1 1 1 0 Presenilin Peroxin-3 PF04882.12 CDJ59569.1 - 7.2 5.5 10.0 9 5.2 10.0 1.1 1 0 0 1 1 1 0 Peroxin-3 EF-hand_4 PF12763.7 CDJ59570.1 - 6.2e-15 55.0 0.0 6.9e-06 26.0 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CDJ59570.1 - 1.9e-06 28.2 0.0 0.0074 16.7 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ59570.1 - 3.4e-06 26.5 0.0 0.16 12.0 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDJ59570.1 - 1.1e-05 24.7 0.0 0.051 13.1 0.0 2.9 2 0 0 2 2 2 2 EF hand DUF2722 PF10846.8 CDJ59570.1 - 0.0019 17.3 2.1 0.0019 17.3 2.1 8.2 4 3 3 7 7 7 1 Protein of unknown function (DUF2722) EF-hand_5 PF13202.6 CDJ59570.1 - 0.056 13.0 0.0 10 5.8 0.0 2.8 2 0 0 2 2 2 0 EF hand CBP_BcsG PF11658.8 CDJ59571.1 - 0.096 11.1 1.6 0.1 11.0 1.6 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG SKN1 PF03935.15 CDJ59571.1 - 0.15 10.4 0.1 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Amnionless PF14828.6 CDJ59571.1 - 0.31 9.8 0.6 0.31 9.8 0.6 1.1 1 0 0 1 1 1 0 Amnionless DUF4834 PF16118.5 CDJ59571.1 - 0.66 11.0 3.3 1.4 10.0 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 CDJ59571.1 - 0.74 10.0 10.3 1.2 9.3 10.3 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GPI2 PF06432.11 CDJ59571.1 - 4 6.8 7.3 5.4 6.4 7.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ion_trans PF00520.31 CDJ59572.1 - 1.3e-10 41.0 0.5 1.5e-10 40.8 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDJ59572.1 - 0.022 13.5 4.3 0.029 13.1 4.3 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF3446 PF11928.8 CDJ59572.1 - 0.053 13.8 13.0 0.42 11.0 12.8 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4763 PF15960.5 CDJ59572.1 - 0.2 10.9 11.0 2.6 7.3 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Corona_nucleoca PF00937.18 CDJ59572.1 - 0.56 9.2 3.8 0.91 8.5 3.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FSIP1 PF15554.6 CDJ59573.1 - 0.004 16.3 1.3 0.25 10.4 0.1 2.0 2 0 0 2 2 2 2 FSIP1 family Lin-8 PF03353.15 CDJ59573.1 - 0.041 13.4 6.1 0.045 13.3 6.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Methyltr_RsmB-F PF01189.17 CDJ59573.1 - 0.087 12.5 0.3 0.18 11.4 0.1 1.7 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF755 PF05501.11 CDJ59573.1 - 0.14 12.4 28.4 0.093 13.0 7.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GREB1 PF15782.5 CDJ59573.1 - 0.77 6.8 13.6 0.9 6.6 13.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 CDJ59573.1 - 0.82 8.3 14.8 1 7.9 14.8 1.1 1 0 0 1 1 1 0 Hamartin protein Adeno_PV PF03910.13 CDJ59573.1 - 1.4 7.6 7.2 1.8 7.2 7.2 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Secretin_N_2 PF07655.13 CDJ59573.1 - 1.8 9.2 19.0 4.3 7.9 4.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain SR-25 PF10500.9 CDJ59573.1 - 1.8 8.1 37.6 1.1 8.8 14.3 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 CDJ59573.1 - 3.2 7.6 13.7 4.1 7.2 13.7 1.1 1 0 0 1 1 1 0 SPX domain Med13_C PF06333.12 CDJ59573.1 - 3.9 6.6 15.2 5 6.3 15.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rtf2 PF04641.12 CDJ59573.1 - 4.2 6.7 9.3 8.9 5.6 9.3 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger SRP-alpha_N PF04086.13 CDJ59573.1 - 5.1 6.9 11.7 6 6.7 11.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOG2 PF10428.9 CDJ59573.1 - 5.2 6.2 18.7 6.1 5.9 18.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Transposase_24 PF03004.14 CDJ59573.1 - 7.8 6.6 10.7 3 8.0 0.9 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) RIP PF00161.19 CDJ59575.1 - 0.0063 16.1 0.9 0.014 15.0 0.9 1.7 1 1 0 1 1 1 1 Ribosome inactivating protein RskA PF10099.9 CDJ59576.1 - 0.0025 18.1 0.7 0.0025 18.1 0.7 3.4 1 1 1 3 3 3 1 Anti-sigma-K factor rskA CENP-O PF09496.10 CDJ59576.1 - 0.012 15.6 10.7 0.017 15.1 10.7 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component UEV PF05743.13 CDJ59576.1 - 0.039 13.8 0.9 7.6 6.4 1.9 2.2 2 0 0 2 2 2 0 UEV domain Gti1_Pac2 PF09729.9 CDJ59576.1 - 0.049 13.7 6.9 0.074 13.1 6.9 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4710 PF15828.5 CDJ59576.1 - 0.094 12.8 0.1 0.094 12.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Asp-B-Hydro_N PF05279.11 CDJ59576.1 - 0.12 12.4 13.0 0.14 12.2 13.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S46 PF10459.9 CDJ59576.1 - 0.13 10.9 15.6 0.14 10.7 15.6 1.0 1 0 0 1 1 1 0 Peptidase S46 Presenilin PF01080.17 CDJ59576.1 - 0.13 11.0 15.2 0.16 10.7 15.2 1.1 1 0 0 1 1 1 0 Presenilin Neuraminidase PF18413.1 CDJ59576.1 - 0.14 11.9 7.9 0.21 11.3 7.9 1.2 1 0 0 1 1 1 0 Neuraminidase-like domain Exonuc_VII_L PF02601.15 CDJ59576.1 - 0.14 11.7 16.1 0.18 11.4 16.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.6 CDJ59576.1 - 0.15 12.1 9.0 0.22 11.5 9.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dicty_REP PF05086.12 CDJ59576.1 - 0.23 9.4 8.5 0.28 9.1 8.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4876 PF16215.5 CDJ59576.1 - 0.26 11.3 3.9 0.73 9.8 4.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4876) SLC12 PF03522.15 CDJ59576.1 - 0.43 9.6 14.2 0.53 9.3 14.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Het-C PF07217.11 CDJ59576.1 - 0.43 9.0 9.3 0.52 8.8 9.3 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF1117 PF06547.12 CDJ59576.1 - 0.47 11.0 5.1 9.1 6.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1117) V_ATPase_I PF01496.19 CDJ59576.1 - 0.48 8.3 13.2 0.53 8.1 13.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ThylakoidFormat PF11264.8 CDJ59576.1 - 0.49 10.1 13.1 0.93 9.1 13.1 1.6 1 0 0 1 1 1 0 Thylakoid formation protein Neur_chan_memb PF02932.16 CDJ59576.1 - 0.94 9.5 9.8 1.2 9.1 9.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRP-S27 PF10037.9 CDJ59576.1 - 1.5 7.6 20.7 2.1 7.1 20.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 SID-1_RNA_chan PF13965.6 CDJ59576.1 - 2.1 6.7 3.5 2.6 6.3 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ59576.1 - 2.3 7.4 5.4 3.2 6.9 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CDJ59576.1 - 2.4 7.9 15.9 3.8 7.3 15.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 CDJ59576.1 - 2.5 7.4 16.6 0.95 8.8 14.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PIP5K PF01504.18 CDJ59576.1 - 2.5 7.2 9.9 3.8 6.7 9.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CAF1 PF04857.20 CDJ59576.1 - 2.8 7.0 9.8 3.8 6.6 9.8 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease LMBR1 PF04791.16 CDJ59576.1 - 2.9 6.7 6.3 3.1 6.6 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CLN3 PF02487.17 CDJ59576.1 - 3 6.8 9.3 5.1 6.0 9.3 1.3 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 CDJ59576.1 - 5.7 5.6 12.7 7.9 5.2 12.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter F-protein PF00469.20 CDJ59576.1 - 6.9 6.2 14.3 9.7 5.7 14.3 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Suf PF05843.14 CDJ59576.1 - 7 6.5 26.6 15 5.5 26.6 1.5 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Membralin PF09746.9 CDJ59576.1 - 8.7 5.3 10.1 11 4.9 10.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein TFIIA PF03153.13 CDJ59577.1 - 0.0022 18.1 40.0 0.0028 17.7 40.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 CDJ59577.1 - 0.04 14.4 1.3 0.058 13.9 1.3 1.3 1 0 0 1 1 1 0 AAA domain SOBP PF15279.6 CDJ59577.1 - 0.1 13.2 19.0 0.13 12.9 19.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0564 PF10595.9 CDJ59577.1 - 0.25 10.4 13.3 0.35 9.9 13.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 GREB1 PF15782.5 CDJ59577.1 - 4.8 4.2 20.2 6.1 3.8 20.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM232 PF15877.5 CDJ59577.1 - 7.3 5.5 6.8 9.8 5.0 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein family 232 ECM1 PF05782.11 CDJ59577.1 - 8.6 5.2 19.6 12 4.7 19.6 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PP2C PF00481.21 CDJ59578.1 - 6.1e-14 52.3 0.3 6.1e-14 52.3 0.3 7.0 5 2 2 7 7 7 1 Protein phosphatase 2C TFIIA PF03153.13 CDJ59578.1 - 0.00026 21.1 29.4 0.00026 21.1 29.4 11.9 3 3 5 8 8 8 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ59578.1 - 0.019 15.0 0.4 0.019 15.0 0.4 23.9 10 5 3 13 13 13 0 Unstructured region C-term to UIM in Ataxin3 DUF1645 PF07816.11 CDJ59578.1 - 0.16 12.5 0.1 0.16 12.5 0.1 16.4 8 5 2 11 11 11 0 Protein of unknown function (DUF1645) SAP18 PF06487.12 CDJ59579.1 - 1.2e-12 48.2 0.0 1.2e-12 48.2 0.0 3.4 2 1 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) TFIIA PF03153.13 CDJ59579.1 - 0.56 10.2 44.8 0.086 12.8 40.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 CDJ59580.1 - 0.017 14.0 7.5 0.019 13.8 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF305 PF03713.13 CDJ59580.1 - 0.54 10.4 9.0 4.5 7.4 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF305) Macoilin PF09726.9 CDJ59581.1 - 0.00045 18.9 34.7 0.00071 18.3 34.7 1.2 1 0 0 1 1 1 1 Macoilin family SpoIIIAH PF12685.7 CDJ59581.1 - 0.0035 17.2 12.2 0.0035 17.2 12.2 2.7 2 1 0 2 2 2 1 SpoIIIAH-like protein TFIIA PF03153.13 CDJ59581.1 - 0.48 10.4 21.0 0.62 10.0 21.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 CDJ59581.1 - 3.8 7.9 11.0 0.65 10.4 6.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF948 PF06103.11 CDJ59581.1 - 7.7 6.8 7.3 1.9 8.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CDJ59581.1 - 7.8 6.5 11.4 0.95 9.5 3.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 CDJ59582.1 - 7.2e-09 36.1 0.1 0.0062 17.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ59582.1 - 5.4e-08 33.2 0.1 0.0025 18.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ59582.1 - 8.3e-07 28.8 0.0 0.39 11.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ59582.1 - 1.2e-05 25.5 0.0 1.3 9.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CDJ59582.1 - 0.00092 19.5 0.1 0.29 11.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF966 PF06136.13 CDJ59582.1 - 2.6 7.7 45.8 1.4 8.6 23.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) CAC1F_C PF16885.5 CDJ59582.1 - 9.8 5.7 35.4 0.82 9.3 17.8 2.4 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term JUPITER PF17054.5 CDJ59583.1 - 2.3 7.6 4.4 3.5 7.0 3.7 1.5 1 1 0 1 1 1 0 Microtubule-Associated protein Jupiter AF-4 PF05110.13 CDJ59584.1 - 2e-05 23.0 16.8 2e-05 23.0 16.8 2.1 2 0 0 2 2 2 2 AF-4 proto-oncoprotein Spt20 PF12090.8 CDJ59584.1 - 0.00012 21.7 5.6 0.00012 21.7 5.6 3.6 2 1 0 2 2 2 1 Spt20 family Macoilin PF09726.9 CDJ59584.1 - 0.0075 14.9 36.3 0.011 14.3 36.3 1.3 1 0 0 1 1 1 1 Macoilin family RskA PF10099.9 CDJ59584.1 - 0.058 13.7 0.0 0.058 13.7 0.0 5.1 1 1 0 2 2 2 0 Anti-sigma-K factor rskA SLC12 PF03522.15 CDJ59584.1 - 2.8 6.9 36.4 3.9 6.4 2.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Pox_A12 PF04651.13 CDJ59584.1 - 5.9 6.9 13.5 0.16 12.0 6.8 1.8 2 0 0 2 2 2 0 Poxvirus A12 protein DUF2115 PF09888.9 CDJ59584.1 - 6.4 7.3 18.6 0.57 10.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2052 PF09747.9 CDJ59584.1 - 7.8 6.6 34.0 7.9 6.5 27.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Metallophos PF00149.28 CDJ59585.1 - 9.8e-37 127.4 0.1 1.4e-36 127.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NYD-SP12_N PF15015.6 CDJ59585.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Glyco_hydro_65N PF03636.15 CDJ59585.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain tRNA-synt_1 PF00133.22 CDJ59587.1 - 9.4e-172 572.4 0.0 3.8e-171 570.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ59587.1 - 3e-24 85.7 0.0 8.6e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ59587.1 - 3.5e-14 52.4 0.0 0.00031 19.6 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDJ59587.1 - 6.2e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PGAP1 PF07819.13 CDJ59587.1 - 0.12 12.1 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein TFIIA PF03153.13 CDJ59588.1 - 0.0013 18.8 56.9 0.0013 18.8 56.9 15.5 10 4 2 14 14 14 2 Transcription factor IIA, alpha/beta subunit Surface_antigen PF11054.8 CDJ59590.1 - 8e-14 51.9 1.0 9.4e-13 48.4 0.5 2.5 2 1 0 2 2 2 1 Sporozoite TA4 surface antigen RIFIN PF02009.16 CDJ59591.1 - 5.1e-05 23.3 7.1 5.9e-05 23.1 7.1 1.1 1 0 0 1 1 1 1 Rifin Presenilin PF01080.17 CDJ59591.1 - 0.07 11.9 19.9 0.098 11.4 19.9 1.3 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ59591.1 - 0.11 12.6 8.8 0.15 12.1 8.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CDJ59591.1 - 0.11 11.3 11.7 0.15 10.9 11.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ribosomal_60s PF00428.19 CDJ59591.1 - 0.74 10.4 8.9 0.71 10.5 2.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hydin_ADK PF17213.3 CDJ59591.1 - 1.6 9.0 16.8 2.3 8.4 16.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CDJ59591.1 - 2.3 8.1 24.2 3.3 7.6 24.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4045 PF13254.6 CDJ59591.1 - 2.4 7.7 18.1 3.5 7.2 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) V_ATPase_I PF01496.19 CDJ59591.1 - 2.7 5.8 21.9 3.3 5.5 21.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 CDJ59591.1 - 3 7.9 32.5 0.29 11.2 28.4 1.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SLC12 PF03522.15 CDJ59591.1 - 4.3 6.3 22.5 5.2 6.0 22.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CDJ59591.1 - 4.3 4.3 19.8 5 4.1 19.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SARAF PF06682.12 CDJ59592.1 - 0.00013 21.7 15.1 0.00015 21.5 15.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SOG2 PF10428.9 CDJ59592.1 - 0.0035 16.6 12.7 0.0038 16.5 12.7 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein RR_TM4-6 PF06459.12 CDJ59592.1 - 0.0057 16.5 16.6 0.0069 16.3 16.6 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CDJ59592.1 - 0.0091 15.0 10.6 0.012 14.7 10.6 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) ASD2 PF08687.11 CDJ59592.1 - 0.0099 15.5 16.8 0.012 15.2 16.8 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Spore_coat_CotO PF14153.6 CDJ59592.1 - 0.017 15.0 28.4 0.03 14.2 28.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 CDJ59592.1 - 0.018 13.4 10.6 0.018 13.4 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF908 PF06012.12 CDJ59592.1 - 0.021 14.3 11.8 0.023 14.2 11.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SLC12 PF03522.15 CDJ59592.1 - 0.021 13.9 15.9 0.024 13.7 15.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Pex14_N PF04695.13 CDJ59592.1 - 0.025 15.2 32.7 0.034 14.8 32.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAPS PF04499.15 CDJ59592.1 - 0.029 13.2 8.7 0.029 13.2 8.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 CDJ59592.1 - 0.029 13.2 16.7 0.035 12.9 16.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EPL1 PF10513.9 CDJ59592.1 - 0.035 14.5 21.5 0.053 13.9 21.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like G0-G1_switch_2 PF15103.6 CDJ59592.1 - 0.037 14.4 7.1 0.037 14.4 7.1 2.2 1 1 1 2 2 2 0 G0/G1 switch protein 2 Presenilin PF01080.17 CDJ59592.1 - 0.038 12.8 23.1 0.046 12.5 23.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ59592.1 - 0.074 13.1 11.2 0.087 12.9 11.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sox_N PF12444.8 CDJ59592.1 - 0.076 14.2 2.6 0.076 14.2 2.6 2.2 1 1 1 2 2 1 0 Sox developmental protein N terminal PIP5K PF01504.18 CDJ59592.1 - 0.087 12.0 11.2 0.11 11.7 11.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF775 PF05603.12 CDJ59592.1 - 0.089 12.3 17.5 0.32 10.5 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Endostatin PF06482.11 CDJ59592.1 - 0.099 12.1 15.3 0.11 11.9 15.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Velvet PF11754.8 CDJ59592.1 - 0.12 12.3 14.6 0.16 11.9 14.6 1.3 1 0 0 1 1 1 0 Velvet factor CLN3 PF02487.17 CDJ59592.1 - 0.13 11.3 9.8 0.18 10.8 9.8 1.2 1 0 0 1 1 1 0 CLN3 protein Rtf2 PF04641.12 CDJ59592.1 - 0.13 11.6 17.3 0.17 11.3 17.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger MDM31_MDM32 PF08118.11 CDJ59592.1 - 0.17 10.5 10.7 0.22 10.2 10.7 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4551 PF15087.6 CDJ59592.1 - 0.18 10.6 15.3 0.2 10.4 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3807 PF12720.7 CDJ59592.1 - 0.19 12.0 28.3 0.27 11.5 28.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AUX_IAA PF02309.16 CDJ59592.1 - 0.21 11.4 9.2 0.23 11.3 9.2 1.1 1 0 0 1 1 1 0 AUX/IAA family RNA_pol_Rbc25 PF08292.12 CDJ59592.1 - 0.25 11.6 15.5 0.19 12.0 2.0 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Serinc PF03348.15 CDJ59592.1 - 0.25 10.2 6.5 0.29 10.0 6.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peroxin-3 PF04882.12 CDJ59592.1 - 0.26 10.2 22.9 0.32 10.0 22.9 1.0 1 0 0 1 1 1 0 Peroxin-3 ALMT PF11744.8 CDJ59592.1 - 0.31 9.8 12.8 0.36 9.6 12.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GREB1 PF15782.5 CDJ59592.1 - 0.34 8.0 14.9 0.34 8.0 14.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAGA_bind PF06217.12 CDJ59592.1 - 0.35 11.1 14.2 0.4 10.9 14.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2828 PF11443.8 CDJ59592.1 - 0.38 8.8 14.6 0.47 8.5 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sin_N PF04801.13 CDJ59592.1 - 0.52 9.5 28.5 0.68 9.1 28.5 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region FAM60A PF15396.6 CDJ59592.1 - 0.65 10.0 16.1 0.83 9.6 16.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 CDJ59592.1 - 0.67 8.1 34.7 0.75 8.0 34.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2370 PF10176.9 CDJ59592.1 - 0.68 9.5 6.4 0.89 9.2 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) V_ATPase_I PF01496.19 CDJ59592.1 - 0.69 7.7 17.1 0.95 7.3 17.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2347 PF09804.9 CDJ59592.1 - 0.77 9.3 4.9 1.1 8.8 4.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4746 PF15928.5 CDJ59592.1 - 0.92 8.9 17.8 1.3 8.4 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EIIBC-GUT_N PF03612.14 CDJ59592.1 - 0.95 9.2 17.1 0.45 10.2 5.0 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 CDJ59592.1 - 1.1 7.1 45.4 1.5 6.6 45.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.10 CDJ59592.1 - 1.1 9.3 16.9 1.1 9.4 6.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal XRN_M PF17846.1 CDJ59592.1 - 1.2 8.0 14.2 1.5 7.7 14.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SWIRM-assoc_2 PF16496.5 CDJ59592.1 - 1.2 7.9 18.6 1.6 7.5 18.6 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Senescence_reg PF04520.13 CDJ59592.1 - 1.2 9.9 17.8 1.7 9.4 17.8 1.1 1 0 0 1 1 1 0 Senescence regulator RP-C_C PF11800.8 CDJ59592.1 - 1.4 9.0 16.1 2.1 8.4 16.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Plasmodium_Vir PF05795.11 CDJ59592.1 - 1.4 8.2 9.7 1.7 8.0 9.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1180 PF06679.12 CDJ59592.1 - 1.9 8.9 8.6 2.8 8.3 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gti1_Pac2 PF09729.9 CDJ59592.1 - 2.3 8.3 17.2 3.3 7.8 17.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SRP-alpha_N PF04086.13 CDJ59592.1 - 2.3 8.1 20.6 3 7.7 20.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 CDJ59592.1 - 2.5 8.2 23.5 3.8 7.6 23.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDRGK PF09756.9 CDJ59592.1 - 2.7 7.6 31.5 4.2 6.9 31.5 1.3 1 0 0 1 1 1 0 DDRGK domain Lin-8 PF03353.15 CDJ59592.1 - 3.4 7.1 25.9 4.4 6.8 25.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1387 PF07139.11 CDJ59592.1 - 3.5 7.3 19.1 4.8 6.8 19.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Kei1 PF08552.11 CDJ59592.1 - 3.5 7.5 10.6 5.3 6.9 10.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tsg PF04668.12 CDJ59592.1 - 3.7 8.2 11.2 11 6.7 4.3 2.1 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Zip PF02535.22 CDJ59592.1 - 4.6 6.4 8.9 6.4 5.9 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 CDJ59592.1 - 5.4 5.7 5.5 6.8 5.4 5.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family Mitofilin PF09731.9 CDJ59592.1 - 5.4 5.7 26.0 6.9 5.4 26.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Auxin_canalis PF05703.11 CDJ59592.1 - 6.2 6.7 8.9 7.6 6.4 8.9 1.1 1 0 0 1 1 1 0 Auxin canalisation Membralin PF09746.9 CDJ59592.1 - 7 5.6 10.4 8.9 5.2 10.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein SKA1 PF07160.12 CDJ59592.1 - 7.7 6.3 22.7 10 5.9 22.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF5094 PF17015.5 CDJ59592.1 - 8 6.5 16.6 10 6.1 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Otopetrin PF03189.13 CDJ59592.1 - 8.3 5.1 9.5 11 4.8 9.5 1.1 1 0 0 1 1 1 0 Otopetrin FixO PF02433.15 CDJ59592.1 - 9.6 5.6 15.4 6.8 6.1 6.5 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO ubiquitin PF00240.23 CDJ59593.1 - 2.4e-20 72.0 0.1 4.6e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDJ59593.1 - 3.4e-07 30.0 0.0 6.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CDJ59593.1 - 3.1e-05 23.8 0.1 8.5e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 CDJ59593.1 - 0.00014 21.9 1.2 0.0087 16.1 0.0 2.5 2 0 0 2 2 2 1 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 CDJ59593.1 - 0.00021 21.4 0.9 0.00021 21.4 0.9 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDJ59593.1 - 0.00054 20.5 1.0 0.00054 20.5 1.0 1.6 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain SUIM_assoc PF16619.5 CDJ59593.1 - 0.00087 19.3 7.4 0.00087 19.3 7.4 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 CUE PF02845.16 CDJ59593.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 CUE domain STI1 PF17830.1 CDJ59593.1 - 0.0041 17.0 3.0 0.0041 17.0 3.0 4.0 3 0 0 3 3 3 1 STI1 domain TBK1_ULD PF18396.1 CDJ59593.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CDJ59593.1 - 0.035 14.5 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_4 PF14555.6 CDJ59593.1 - 0.048 13.5 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Roughex PF06020.11 CDJ59593.1 - 0.81 8.7 7.2 0.074 12.1 0.9 2.0 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 CDJ59593.1 - 1.6 8.3 19.9 0.3 10.7 12.6 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 CDJ59593.1 - 2.5 9.1 7.8 8.4 7.4 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NINJA_B PF16136.5 CDJ59593.1 - 5.1 7.5 8.8 11 6.4 1.9 3.0 2 0 0 2 2 2 0 Putative nuclear localisation signal SPX PF03105.19 CDJ59594.1 - 0.007 16.3 12.7 0.031 14.2 4.5 2.4 2 0 0 2 2 2 2 SPX domain RskA PF10099.9 CDJ59594.1 - 0.033 14.5 0.5 0.033 14.5 0.5 3.7 3 1 1 4 4 4 0 Anti-sigma-K factor rskA Plasmodium_Vir PF05795.11 CDJ59594.1 - 3 7.2 7.2 12 5.2 0.5 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DHHW PF14286.6 CDJ59594.1 - 7.2 5.8 7.5 23 4.1 3.1 2.4 2 0 0 2 2 2 0 DHHW protein DEAD PF00270.29 CDJ59595.1 - 1.2e-43 148.9 1.0 2.5e-43 147.9 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ59595.1 - 6.9e-30 103.6 2.3 2.7e-29 101.7 0.4 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ59595.1 - 5e-06 26.6 0.0 5e-06 26.6 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.25 CDJ59595.1 - 0.0022 17.4 0.0 0.0053 16.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 CDJ59595.1 - 0.015 15.3 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 CDJ59595.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 0 Helicase Presenilin PF01080.17 CDJ59595.1 - 0.02 13.7 0.9 0.026 13.3 0.9 1.2 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CDJ59595.1 - 0.04 14.1 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 DDHD domain PapG_C PF03628.13 CDJ59595.1 - 0.076 12.9 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 PapG chaperone-binding domain SR-25 PF10500.9 CDJ59595.1 - 0.2 11.2 15.4 0.29 10.7 15.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CMS1 PF14617.6 CDJ59595.1 - 0.24 10.7 0.0 0.24 10.7 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit TERB2 PF15101.6 CDJ59595.1 - 0.57 10.2 7.8 1.1 9.3 7.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GREB1 PF15782.5 CDJ59595.1 - 0.93 6.5 8.6 1.2 6.2 8.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_22 PF13401.6 CDJ59595.1 - 2.8 8.2 5.8 0.4 10.9 0.1 2.5 3 1 0 3 3 2 0 AAA domain DUF4692 PF15763.5 CDJ59595.1 - 4.2 7.8 10.6 7.2 7.0 10.6 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TFIIA PF03153.13 CDJ59595.1 - 5.2 7.0 15.4 9.9 6.0 15.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDZ_3 PF17815.1 CDJ59597.1 - 1.7e-20 73.3 0.0 6e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 CDJ59597.1 - 5.1e-12 46.9 0.1 9.1e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CDJ59597.1 - 5.4e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 CDJ59597.1 - 6.7e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDJ59597.1 - 0.00049 20.4 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ59597.1 - 0.025 14.4 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Peptidase_S46 PF10459.9 CDJ59597.1 - 0.033 12.8 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 CDJ59597.1 - 0.046 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_C2 PF00648.21 CDJ59597.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease RRM_1 PF00076.22 CDJ59598.1 - 6.7e-09 35.4 0.3 1.2e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDJ59598.1 - 0.019 14.6 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ59598.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ59598.1 - 0.029 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Mannosyl_trans4 PF15971.5 CDJ59598.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase RICTOR_M PF14666.6 CDJ59601.1 - 0.0046 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 CDJ59601.1 - 0.52 9.2 13.3 0.12 11.3 0.5 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Cohesin_HEAT PF12765.7 CDJ59602.1 - 0.00021 21.5 0.4 0.16 12.3 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CDJ59602.1 - 0.00093 19.3 5.9 0.28 11.6 0.2 5.5 4 0 0 4 4 4 2 HEAT repeat Rootletin PF15035.6 CDJ59603.1 - 0.038 14.0 0.6 0.066 13.2 0.6 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SR-25 PF10500.9 CDJ59604.1 - 1.1 8.8 43.9 0.02 14.5 18.7 2.1 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ59604.1 - 7.9 6.0 59.7 4.5 6.8 21.1 2.2 2 0 0 2 2 2 0 Spt20 family Spc7_N PF15402.6 CDJ59604.1 - 9.7 4.3 30.9 25 2.9 30.9 1.6 1 1 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Androgen_recep PF02166.16 CDJ59606.1 - 0.052 12.4 6.2 0.052 12.4 6.2 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 CDJ59606.1 - 0.13 11.9 7.6 0.13 11.8 7.6 1.0 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ59606.1 - 0.22 10.6 5.3 0.22 10.7 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 CDJ59606.1 - 0.34 11.0 11.0 0.48 10.5 11.0 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 E_Pc_C PF06752.12 CDJ59606.1 - 0.56 10.3 9.0 0.66 10.0 9.0 1.0 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus RTC_insert PF05189.13 CDJ59608.1 - 1.7e-14 54.2 6.5 9.2e-14 51.8 6.5 2.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 CDJ59608.1 - 7.5e-07 28.6 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Spt20 PF12090.8 CDJ59608.1 - 0.02 14.5 7.5 0.028 14.0 2.1 2.1 2 0 0 2 2 2 0 Spt20 family WD40 PF00400.32 CDJ59609.1 - 7.1e-20 71.0 12.4 0.0062 17.4 0.6 9.9 10 0 0 10 10 10 5 WD domain, G-beta repeat Utp12 PF04003.12 CDJ59609.1 - 5.3e-08 33.1 4.5 1.6e-07 31.6 4.5 1.9 1 0 0 1 1 1 1 Dip2/Utp12 Family TFIIA PF03153.13 CDJ59609.1 - 0.037 14.0 36.5 0.02 14.9 16.0 4.3 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 CDJ59609.1 - 0.93 9.4 5.4 0.33 10.9 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Campylo_MOMP PF05538.11 CDJ59609.1 - 1 8.3 6.4 2.2 7.2 6.4 1.5 1 0 0 1 1 1 0 Campylobacter major outer membrane protein Cellulose_synt PF03552.14 CDJ59609.1 - 1.8 7.0 5.9 3.7 5.9 5.9 1.4 1 0 0 1 1 1 0 Cellulose synthase PQQ_3 PF13570.6 CDJ59609.1 - 1.8 9.1 6.1 17 6.1 0.0 4.6 6 0 0 6 6 6 0 PQQ-like domain Connexin PF00029.19 CDJ59609.1 - 3.5 7.3 14.5 14 5.4 7.5 2.9 3 0 0 3 3 3 0 Connexin SPX PF03105.19 CDJ59609.1 - 6.8 6.5 20.9 1.4 8.7 5.1 3.1 3 0 0 3 3 3 0 SPX domain GREB1 PF15782.5 CDJ59609.1 - 8.6 3.3 16.8 3.6 4.6 10.1 2.3 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer BT1 PF03092.16 CDJ59610.1 - 0.1 10.8 9.0 0.79 7.9 4.5 3.1 2 0 0 2 2 2 0 BT1 family CPSase_sm_chain PF00988.22 CDJ59611.1 - 1.3e-43 147.9 0.0 2.5e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CDJ59611.1 - 4.6e-39 134.2 0.0 8.1e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D2 PF02786.17 CDJ59611.1 - 2.7e-37 128.3 0.0 5.1e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_C26 PF07722.13 CDJ59611.1 - 3.5e-08 33.5 0.1 7.3e-06 25.9 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp PF02222.22 CDJ59611.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DJ-1_PfpI PF01965.24 CDJ59611.1 - 0.016 15.0 0.0 0.094 12.5 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family Dala_Dala_lig_C PF07478.13 CDJ59611.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 CDJ59611.1 - 0.065 12.7 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 ATP-grasp domain YppG PF14179.6 CDJ59611.1 - 1.3 9.8 8.8 3.6 8.3 8.8 1.6 1 0 0 1 1 1 0 YppG-like protein Syntaxin_2 PF14523.6 CDJ59612.1 - 0.076 13.4 3.5 0.37 11.2 0.9 3.2 3 0 0 3 3 3 0 Syntaxin-like protein Serinc PF03348.15 CDJ59612.1 - 0.18 10.7 0.5 0.46 9.3 0.5 1.7 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2730 PF10805.8 CDJ59612.1 - 1.8 8.7 5.0 7.2 6.8 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) PA26 PF04636.13 CDJ59612.1 - 8.6 5.2 8.6 0.38 9.6 1.9 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Pkinase PF00069.25 CDJ59614.1 - 4.9e-52 176.9 7.4 1.1e-51 175.7 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59614.1 - 4.8e-26 91.6 0.0 1.5e-25 90.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RskA PF10099.9 CDJ59614.1 - 0.0002 21.7 20.9 0.002 18.4 20.9 2.0 1 1 0 1 1 1 1 Anti-sigma-K factor rskA EPL1 PF10513.9 CDJ59614.1 - 0.004 17.6 2.1 0.004 17.6 2.1 2.9 2 1 0 2 2 1 1 Enhancer of polycomb-like NAM-associated PF14303.6 CDJ59614.1 - 0.0047 17.7 1.2 0.0047 17.7 1.2 2.4 1 1 1 2 2 1 1 No apical meristem-associated C-terminal domain DcuA_DcuB PF03605.14 CDJ59614.1 - 0.053 12.4 4.8 0.099 11.5 4.8 1.4 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4179 PF13786.6 CDJ59614.1 - 0.11 13.0 0.6 5.2 7.6 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) SelP_N PF04592.14 CDJ59614.1 - 0.33 10.3 21.9 0.12 11.7 9.4 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Shadoo PF14999.6 CDJ59614.1 - 0.59 10.2 11.9 1.7 8.7 2.6 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Cellulose_synt PF03552.14 CDJ59614.1 - 0.94 7.9 2.3 1.6 7.1 2.3 1.3 1 0 0 1 1 1 0 Cellulose synthase GAGA_bind PF06217.12 CDJ59614.1 - 0.99 9.6 12.6 1.4 9.1 12.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_pol_Rpb1_2 PF00623.20 CDJ59614.1 - 2.8 8.1 5.2 0.85 9.8 0.8 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 Peptidase_S15 PF02129.18 CDJ59614.1 - 3.5 7.1 18.8 0.033 13.8 8.6 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FYDLN_acid PF09538.10 CDJ59614.1 - 3.6 8.3 15.2 1.6 9.4 6.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SurA_N_2 PF13623.6 CDJ59614.1 - 5.3 6.9 19.4 12 5.7 19.4 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Kinase-like PF14531.6 CDJ59615.1 - 3.7e-06 26.5 0.0 3.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 CDJ59615.1 - 0.018 14.4 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Kinase-like PF14531.6 CDJ59616.1 - 0.00066 19.1 0.0 0.66 9.2 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.25 CDJ59617.1 - 9.1e-19 67.8 0.0 4e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59617.1 - 5.4e-06 25.9 0.0 2.5e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ59617.1 - 1.8e-05 24.2 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDJ59617.1 - 0.019 14.9 0.9 0.065 13.1 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Nup54_C PF18437.1 CDJ59617.1 - 0.64 10.0 2.8 5.3 7.0 0.1 2.8 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Solute_trans_a PF03619.16 CDJ59618.1 - 1.5e-17 64.0 0.3 3.2e-09 36.7 0.1 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha Pro_isomerase PF00160.21 CDJ59620.1 - 3.4e-41 141.1 0.0 3.9e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kinase-like PF14531.6 CDJ59621.1 - 8.2e-06 25.3 0.0 3.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 CDJ59621.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ59621.1 - 0.00028 20.4 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ59622.1 - 0.00026 20.4 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 CDJ59622.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Quaking_NLS PF16551.5 CDJ59622.1 - 0.016 14.9 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking Adenylate_cycl PF01295.18 CDJ59622.1 - 0.07 11.7 0.0 0.45 9.1 0.0 2.1 3 0 0 3 3 3 0 Adenylate cyclase, class-I Complex1_LYR PF05347.15 CDJ59623.1 - 0.069 13.2 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Methyltr_RsmF_N PF17125.5 CDJ59623.1 - 0.097 13.2 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF cIII PF08134.11 CDJ59623.1 - 0.17 11.7 0.6 0.63 9.8 0.5 1.8 2 0 0 2 2 2 0 cIII protein family tRNA-synt_1b PF00579.25 CDJ59624.1 - 3.2e-16 59.5 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Macoilin PF09726.9 CDJ59624.1 - 0.00084 18.0 5.4 0.00084 18.0 5.4 1.1 1 0 0 1 1 1 1 Macoilin family Menin PF05053.13 CDJ59624.1 - 0.068 11.5 4.2 0.075 11.4 4.2 1.1 1 0 0 1 1 1 0 Menin Apc15p PF05841.11 CDJ59624.1 - 0.13 13.1 4.4 0.49 11.2 3.6 2.0 2 0 0 2 2 2 0 Apc15p protein Apt1 PF10351.9 CDJ59624.1 - 0.33 9.7 10.6 0.4 9.5 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ59624.1 - 0.55 10.1 11.3 0.63 9.9 11.3 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 CDJ59624.1 - 1.7 7.3 4.1 2.3 6.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF1635 PF07795.11 CDJ59624.1 - 6.2 6.6 8.3 9.7 6.0 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SUZ PF12752.7 CDJ59624.1 - 7.4 7.4 18.8 1.4e+03 0.1 18.8 2.2 1 1 0 1 1 1 0 SUZ domain Pkinase PF00069.25 CDJ59625.1 - 0.0017 17.8 1.4 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DLIC PF05783.11 CDJ59625.1 - 0.1 11.4 1.9 0.11 11.3 1.9 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Presenilin PF01080.17 CDJ59625.1 - 4 6.1 4.2 4.6 5.9 4.2 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CDJ59625.1 - 6.2 6.4 13.4 7.9 6.0 13.4 1.1 1 0 0 1 1 1 0 Spt20 family PUF PF00806.19 CDJ59626.1 - 4.3e-41 136.3 1.4 4.9e-05 22.8 0.0 8.3 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Sacchrp_dh_NADP PF03435.18 CDJ59626.1 - 0.052 13.8 0.1 1.9 8.7 0.0 3.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ANAPC4_WD40 PF12894.7 CDJ59627.1 - 0.054 13.8 0.0 41 4.6 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PAN_4 PF14295.6 CDJ59629.1 - 9.3e-07 28.7 0.6 1.8e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CDJ59629.1 - 0.043 13.9 1.3 0.18 12.0 1.3 2.1 1 0 0 1 1 1 0 PAN-like domain SR-25 PF10500.9 CDJ59630.1 - 0.00023 20.9 3.8 0.00029 20.5 3.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ59630.1 - 0.041 13.2 5.6 0.041 13.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIM3 PF17096.5 CDJ59630.1 - 0.046 14.7 2.1 0.046 14.7 2.1 2.0 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF775 PF05603.12 CDJ59630.1 - 0.085 12.4 7.2 0.11 12.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PA26 PF04636.13 CDJ59630.1 - 0.11 11.4 4.8 0.12 11.3 4.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Suf PF05843.14 CDJ59630.1 - 0.2 11.6 9.8 0.22 11.5 9.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.15 CDJ59630.1 - 0.36 10.6 13.4 0.47 10.2 13.4 1.2 1 0 0 1 1 1 0 Septum formation initiator PIP5K PF01504.18 CDJ59630.1 - 0.44 9.7 5.6 0.53 9.5 5.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase MMR1 PF08505.10 CDJ59630.1 - 0.6 10.4 12.4 0.77 10.0 12.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 CDJ59630.1 - 0.67 8.7 9.0 0.8 8.4 9.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4199 PF13858.6 CDJ59630.1 - 0.92 9.9 2.0 1.1 9.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Neur_chan_memb PF02932.16 CDJ59630.1 - 3.4 7.7 8.0 4.4 7.3 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ59630.1 - 3.9 6.1 5.1 1.9 7.1 3.4 1.3 1 1 0 1 1 1 0 Ureide permease FmiP_Thoc5 PF09766.9 CDJ59630.1 - 4 6.6 17.6 0.1 11.9 11.6 1.3 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Activator_LAG-3 PF11498.8 CDJ59630.1 - 4 6.3 31.1 5.8 5.8 31.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pkinase PF00069.25 CDJ59633.1 - 6.3e-06 25.8 0.4 6.3e-06 25.8 0.4 2.9 2 2 1 3 3 3 1 Protein kinase domain RR_TM4-6 PF06459.12 CDJ59633.1 - 0.0011 18.9 10.6 0.0011 18.9 10.6 3.1 3 0 0 3 3 3 1 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 CDJ59633.1 - 0.005 16.5 22.9 0.005 16.5 22.9 3.9 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 CDJ59633.1 - 0.0067 15.8 0.3 0.0067 15.8 0.3 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase RskA PF10099.9 CDJ59633.1 - 0.0088 16.4 13.6 0.0088 16.4 13.6 3.8 3 1 1 4 4 4 2 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ59633.1 - 0.27 10.8 32.7 0.079 12.5 17.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit SMYLE_N PF18615.1 CDJ59633.1 - 1.6 8.2 27.1 1.3 8.5 8.7 2.3 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CNDH2_C PF16858.5 CDJ59633.1 - 3.1 7.6 30.6 0.23 11.3 15.9 2.5 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term GREB1 PF15782.5 CDJ59634.1 - 0.0018 15.5 19.2 0.0018 15.5 19.2 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer DUF966 PF06136.13 CDJ59634.1 - 0.0045 16.8 20.5 0.0052 16.6 20.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Macoilin PF09726.9 CDJ59634.1 - 0.35 9.4 35.1 0.51 8.8 35.1 1.2 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 CDJ59634.1 - 0.6 9.4 37.1 0.96 8.7 37.1 1.2 1 0 0 1 1 1 0 BUD22 Miga PF10265.9 CDJ59634.1 - 3.3 6.6 25.6 4.3 6.2 25.6 1.1 1 0 0 1 1 1 0 Mitoguardin PI3K_1B_p101 PF10486.9 CDJ59634.1 - 4.2 5.0 28.0 5.3 4.7 28.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.13 CDJ59634.1 - 4.5 5.2 42.5 6.2 4.8 42.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Asp-B-Hydro_N PF05279.11 CDJ59634.1 - 7.3 6.6 36.9 11 6.0 36.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAP PF00188.26 CDJ59636.1 - 0.0025 18.7 0.0 0.0033 18.3 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Hydrolase_3 PF08282.12 CDJ59637.1 - 1.7e-20 73.8 0.0 2.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ59637.1 - 2.7e-06 27.1 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ59637.1 - 0.0055 17.0 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CSG2 PF16965.5 CDJ59638.1 - 0.039 12.9 0.5 0.046 12.7 0.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4834 PF16118.5 CDJ59638.1 - 0.044 14.7 1.8 0.044 14.7 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ59638.1 - 0.089 11.5 3.3 0.079 11.7 3.3 1.2 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CDJ59638.1 - 0.22 11.9 5.2 0.085 13.2 2.7 1.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term LMBR1 PF04791.16 CDJ59638.1 - 0.89 8.4 2.3 0.9 8.4 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF775 PF05603.12 CDJ59638.1 - 0.91 9.0 9.7 0.038 13.5 4.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF3573 PF12097.8 CDJ59638.1 - 1.6 7.5 6.7 2.2 7.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PRP38_assoc PF12871.7 CDJ59639.1 - 0.69 10.5 10.4 0.82 10.3 10.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2052 PF09747.9 CDJ59639.1 - 1.5 8.9 18.5 1.8 8.6 18.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PGA2 PF07543.12 CDJ59639.1 - 2 8.4 15.6 3 7.8 15.6 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 SelP_N PF04592.14 CDJ59639.1 - 2 7.8 32.1 3.1 7.1 32.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 CDJ59639.1 - 2.2 7.4 23.3 2.4 7.3 23.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SMYLE_N PF18615.1 CDJ59639.1 - 2.9 7.3 14.0 3.4 7.1 14.0 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Gti1_Pac2 PF09729.9 CDJ59639.1 - 3.7 7.6 19.4 5.9 7.0 19.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Macoilin PF09726.9 CDJ59639.1 - 4.2 5.8 20.5 4.8 5.6 20.5 1.0 1 0 0 1 1 1 0 Macoilin family FAM60A PF15396.6 CDJ59639.1 - 4.5 7.2 20.2 5.7 6.9 20.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.12 CDJ59639.1 - 6 6.1 16.7 8.9 5.6 16.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4551 PF15087.6 CDJ59639.1 - 6.9 5.4 19.4 8.1 5.1 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 CDJ59639.1 - 8.3 4.6 20.5 10 4.3 20.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Erp_C PF06780.11 CDJ59640.1 - 0.39 10.7 1.2 0.6 10.1 0.1 1.9 2 0 0 2 2 2 0 Erp protein C-terminus CCDC24 PF15669.5 CDJ59641.1 - 1.9 8.3 9.8 2 8.3 9.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF4512 PF14975.6 CDJ59641.1 - 2.4 9.0 4.2 3.1 8.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) TAF4 PF05236.14 CDJ59641.1 - 3.3 7.4 11.6 3.7 7.2 11.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Apt1 PF10351.9 CDJ59641.1 - 5.4 5.8 15.6 5.2 5.8 15.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ59641.1 - 8.4 6.2 15.3 8.1 6.2 15.3 1.0 1 0 0 1 1 1 0 SPX domain zf_CCCH_4 PF18345.1 CDJ59642.1 - 8.6e-11 41.5 19.1 4.2e-05 23.4 2.6 4.2 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 CDJ59642.1 - 2.5e-10 40.0 18.4 3.6e-07 29.9 2.2 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ59642.1 - 0.0073 16.1 1.8 0.0073 16.1 1.8 3.7 3 0 0 3 3 3 2 CCCH-type zinc finger NPR3 PF03666.13 CDJ59643.1 - 0.028 13.2 17.7 0.042 12.6 17.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 CDJ59643.1 - 0.68 9.7 29.1 0.086 12.6 22.7 2.1 2 0 0 2 2 2 0 AAA domain Bul1_N PF04425.12 CDJ59643.1 - 0.82 8.4 17.2 1.4 7.5 17.2 1.4 1 0 0 1 1 1 0 Bul1 N terminus Mem_trans PF03547.18 CDJ59643.1 - 0.89 7.9 3.1 0.87 7.9 3.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Membralin PF09746.9 CDJ59643.1 - 1.5 7.8 11.2 2.6 7.0 11.2 1.4 1 0 0 1 1 1 0 Tumour-associated protein Band_3_cyto PF07565.13 CDJ59643.1 - 1.7 8.4 33.8 0.16 11.7 27.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 CDJ59643.1 - 1.7 8.0 21.7 0.42 10.0 18.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Macoilin PF09726.9 CDJ59643.1 - 1.9 7.0 28.8 2.6 6.5 28.8 1.2 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 CDJ59643.1 - 3.7 5.9 20.9 4.8 5.5 20.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF3292 PF11696.8 CDJ59643.1 - 3.7 5.8 17.6 5.9 5.1 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF913 PF06025.12 CDJ59643.1 - 4.6 6.1 15.3 1.5 7.7 12.4 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CDJ59643.1 - 5.2 6.8 31.2 0.29 10.9 23.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 CDJ59643.1 - 5.5 5.1 48.1 0.23 9.7 40.2 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 CDJ59643.1 - 5.9 6.4 29.0 1.2 8.6 23.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Cellulose_synt PF03552.14 CDJ59643.1 - 6.8 5.1 6.3 8.6 4.7 6.3 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.12 CDJ59643.1 - 7.4 5.4 32.1 0.21 10.6 24.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF778 PF05608.12 CDJ59643.1 - 10 6.5 14.1 3.2 8.1 9.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Ribosomal_L6e PF01159.19 CDJ59644.1 - 2.5e-36 124.6 2.0 3.8e-36 124.0 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ycf54 PF10674.9 CDJ59644.1 - 0.14 12.4 0.7 0.24 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Kelch_4 PF13418.6 CDJ59645.1 - 1.6e-18 66.4 0.3 3.7e-05 23.6 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDJ59645.1 - 8.3e-17 61.0 6.8 3.2e-05 24.1 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ59645.1 - 1e-12 47.7 2.6 6.5e-06 26.0 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ59645.1 - 1.5e-09 37.8 1.4 0.39 11.1 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CDJ59645.1 - 1e-06 28.2 0.1 0.45 10.1 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDJ59645.1 - 0.00011 22.0 4.1 1.9 8.6 0.8 4.9 5 0 0 5 5 5 2 Kelch motif DUF3540 PF12059.8 CDJ59645.1 - 0.071 12.9 1.7 0.12 12.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) DUF2420 PF10336.9 CDJ59645.1 - 0.079 13.0 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) DUF148 PF02520.17 CDJ59645.1 - 0.12 12.4 2.2 0.21 11.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF948 PF06103.11 CDJ59645.1 - 0.16 12.3 1.4 0.29 11.4 1.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 CDJ59645.1 - 0.22 10.6 4.0 0.32 10.1 4.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ARGLU PF15346.6 CDJ59645.1 - 0.27 11.1 6.7 0.5 10.3 6.5 1.5 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Sec34 PF04136.15 CDJ59645.1 - 0.28 11.1 3.0 0.66 9.9 3.0 1.5 1 1 0 1 1 1 0 Sec34-like family UPF0242 PF06785.11 CDJ59645.1 - 0.31 11.1 3.1 0.46 10.5 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_30_8 PF06019.11 CDJ59646.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.7 1 1 0 1 1 1 0 Phage GP30.8 protein SUIM_assoc PF16619.5 CDJ59647.1 - 0.36 10.9 11.8 0.4 10.8 11.8 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SpoIIIAH PF12685.7 CDJ59648.1 - 0.0025 17.7 3.2 0.0025 17.7 3.2 2.2 1 1 1 2 2 2 1 SpoIIIAH-like protein Spore_III_AF PF09581.10 CDJ59648.1 - 0.029 14.4 0.2 0.029 14.4 0.2 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) OAD_gamma PF04277.13 CDJ59648.1 - 0.16 12.5 0.1 0.16 12.5 0.1 4.2 2 2 1 3 3 2 0 Oxaloacetate decarboxylase, gamma chain TLP-20 PF06088.11 CDJ59648.1 - 0.51 10.2 11.4 0.45 10.4 1.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3402 PF11882.8 CDJ59648.1 - 0.69 9.0 10.6 0.89 8.6 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CAC1F_C PF16885.5 CDJ59648.1 - 0.7 9.5 15.8 1.1 8.9 15.8 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Merozoite_SPAM PF07133.11 CDJ59648.1 - 0.83 9.6 32.5 0.039 14.0 10.0 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Spt5_N PF11942.8 CDJ59648.1 - 1.1 10.2 34.9 0.094 13.7 15.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3381 PF11861.8 CDJ59648.1 - 1.3 8.8 19.3 1.6 8.5 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PI3K_1B_p101 PF10486.9 CDJ59648.1 - 1.4 6.6 13.0 1.7 6.4 13.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Tmemb_9 PF05434.11 CDJ59648.1 - 1.4 8.8 5.0 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 TMEM9 Nop14 PF04147.12 CDJ59648.1 - 1.8 6.7 30.4 0.028 12.7 8.9 2.0 2 0 0 2 2 2 0 Nop14-like family OATP PF03137.20 CDJ59648.1 - 2.5 6.3 4.0 6.9 4.8 0.2 2.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CDC45 PF02724.14 CDJ59648.1 - 3.9 5.7 25.2 0.18 10.1 7.3 2.0 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 CDJ59648.1 - 4.2 6.6 22.8 4.2 6.6 3.4 2.1 2 0 0 2 2 2 0 NOA36 protein TMEM51 PF15345.6 CDJ59648.1 - 6 6.6 16.2 0.1 12.4 5.3 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 Fer4_24 PF18109.1 CDJ59649.1 - 0.14 12.4 0.5 0.36 11.2 0.5 1.7 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain HTH_38 PF13936.6 CDJ59649.1 - 0.83 9.5 4.6 37 4.2 0.2 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain Surface_antigen PF11054.8 CDJ59650.1 - 6.8e-14 52.1 0.5 1.7e-13 50.8 0.5 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ59651.1 - 0.19 11.4 1.0 13 5.4 0.2 2.2 2 0 0 2 2 2 0 Sporozoite TA4 surface antigen GTP_EFTU PF00009.27 CDJ59653.1 - 8.2e-54 182.1 0.0 1.2e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDJ59653.1 - 6.3e-42 142.4 0.1 2.3e-41 140.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDJ59653.1 - 1.8e-15 57.0 0.8 5.6e-15 55.5 0.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ59653.1 - 0.00022 21.3 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NIF3 PF01784.18 CDJ59653.1 - 0.0027 17.4 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) GTP_EFTU_D4 PF14578.6 CDJ59653.1 - 0.041 13.8 0.4 0.041 13.8 0.4 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RskA PF10099.9 CDJ59654.1 - 0.00042 20.7 8.3 0.00049 20.4 8.3 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ59654.1 - 0.00073 19.6 5.7 0.0012 18.9 4.9 1.8 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ59654.1 - 0.017 14.8 8.5 0.023 14.3 8.5 1.2 1 0 0 1 1 1 0 Spt20 family ANAPC_CDC26 PF10471.9 CDJ59654.1 - 0.026 15.4 11.3 0.062 14.1 11.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF2232 PF09991.9 CDJ59654.1 - 0.093 11.9 0.9 0.12 11.5 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF775 PF05603.12 CDJ59654.1 - 0.12 11.9 2.3 0.13 11.7 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Roughex PF06020.11 CDJ59654.1 - 0.25 10.4 4.3 0.34 9.9 4.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1180 PF06679.12 CDJ59654.1 - 0.63 10.4 7.1 0.58 10.5 6.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2722 PF10846.8 CDJ59654.1 - 0.9 8.4 9.0 1.5 7.7 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ59654.1 - 1.5 9.8 3.7 1.8 9.6 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hydrolase_3 PF08282.12 CDJ59655.1 - 1.1e-20 74.5 0.0 1.1e-18 68.0 0.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ59655.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ59655.1 - 0.0048 17.2 0.0 0.0095 16.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1340 PF07067.11 CDJ59656.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Collagen PF01391.18 CDJ59656.1 - 0.092 12.5 30.8 0.2 11.5 30.8 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF1980 PF09323.10 CDJ59656.1 - 0.74 9.7 3.7 0.26 11.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RCR PF12273.8 CDJ59656.1 - 1.1 10.0 8.1 0.1 13.3 3.6 1.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SR-25 PF10500.9 CDJ59656.1 - 8.1 6.0 45.7 0.14 11.8 9.0 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ59657.1 - 0.0059 16.7 17.4 0.0082 16.2 17.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ59657.1 - 0.025 13.4 12.5 0.034 12.9 12.5 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDJ59657.1 - 0.24 11.2 14.6 0.36 10.6 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 CDJ59657.1 - 1.3 7.8 11.9 1.8 7.3 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Asp-B-Hydro_N PF05279.11 CDJ59657.1 - 2.3 8.2 10.9 3.5 7.6 10.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.9 CDJ59657.1 - 2.5 6.3 18.1 3.3 5.9 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ59657.1 - 3.4 5.9 15.4 4.9 5.3 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 CDJ59657.1 - 3.4 6.3 13.0 4.5 5.9 13.0 1.1 1 0 0 1 1 1 0 Raftlin Lin-8 PF03353.15 CDJ59657.1 - 4.7 6.7 17.6 7.5 6.0 17.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ59657.1 - 8.2 5.3 16.5 12 4.8 16.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ59657.1 - 9.5 6.4 15.6 18 5.6 15.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ATP-synt_10 PF05176.14 CDJ59659.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 ATP10 protein Toxin_35 PF10530.9 CDJ59659.1 - 0.037 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold IMS PF00817.20 CDJ59660.1 - 5.8e-32 110.8 0.0 1.2e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CDJ59660.1 - 2.3e-06 27.9 0.0 0.00088 19.6 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CDJ59660.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DEAD PF00270.29 CDJ59661.1 - 1.4e-37 129.1 0.0 7.4e-37 126.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ59661.1 - 5.4e-16 58.9 10.7 4.1e-11 43.2 0.1 3.8 5 0 0 5 5 5 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDJ59661.1 - 2.9e-14 53.0 0.9 7.3e-14 51.7 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDJ59661.1 - 0.00016 21.7 3.7 0.00019 21.5 0.0 3.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Glutaredoxin PF00462.24 CDJ59662.1 - 3.1e-17 62.5 0.1 4e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CDJ59662.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 CDJ59662.1 - 0.00081 19.8 0.1 0.0018 18.7 0.1 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 CDJ59662.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.6 CDJ59662.1 - 0.018 15.5 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 CDJ59662.1 - 0.019 15.4 0.4 0.053 14.0 0.4 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 CDJ59662.1 - 0.026 14.3 0.5 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain FANCL_C PF11793.8 CDJ59662.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 FANCL C-terminal domain TraF PF13728.6 CDJ59662.1 - 0.041 13.7 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 CDJ59662.1 - 0.044 13.9 0.3 6.6 6.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin STI1 PF17830.1 CDJ59663.1 - 3.5e-05 23.6 1.6 0.0023 17.8 0.3 1.8 1 1 1 2 2 2 2 STI1 domain GerD PF17898.1 CDJ59663.1 - 0.04 13.9 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Spore germination GerD central core domain ComC PF03047.14 CDJ59663.1 - 0.15 11.9 0.3 14 5.6 0.1 2.4 2 0 0 2 2 2 0 COMC family DUF4240 PF14024.6 CDJ59664.1 - 0.0069 16.6 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4240) Cauli_DNA-bind PF03310.13 CDJ59664.1 - 0.33 11.0 1.8 0.87 9.7 0.1 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein SBE2 PF17076.5 CDJ59665.1 - 3.5 5.7 5.6 0.66 8.1 1.0 1.8 2 0 0 2 2 2 0 SBE2, cell-wall formation LMF1 PF06762.14 CDJ59666.1 - 4.2e-27 95.4 5.6 6.1e-17 61.9 0.0 3.1 2 1 1 3 3 3 3 Lipase maturation factor DUF983 PF06170.12 CDJ59666.1 - 0.057 13.8 1.5 7.3 7.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Peptidase_C26 PF07722.13 CDJ59666.1 - 0.24 11.1 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 Neur_chan_memb PF02932.16 CDJ59667.1 - 0.0087 16.1 0.4 6 6.8 0.2 2.7 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 CDJ59667.1 - 0.21 10.1 9.0 0.54 8.7 9.0 1.6 1 1 0 1 1 1 0 Macoilin family Fringe PF02434.16 CDJ59668.1 - 1.1e-17 64.4 0.0 6.7e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 Fringe-like GP40 PF11025.8 CDJ59668.1 - 0.077 12.8 0.3 0.077 12.8 0.3 1.7 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium EXS PF03124.14 CDJ59669.1 - 1.6e-64 218.3 12.7 2.3e-64 217.8 12.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CDJ59669.1 - 2.4e-18 67.2 13.5 2.9e-15 57.1 13.5 2.5 1 1 0 1 1 1 1 SPX domain DUF3445 PF11927.8 CDJ59670.1 - 0.084 12.5 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3445) WD40 PF00400.32 CDJ59671.1 - 1.9e-10 41.1 0.0 0.00014 22.6 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ59671.1 - 0.00061 20.0 0.2 0.078 13.3 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Na_trans_assoc PF06512.13 CDJ59671.1 - 0.041 14.2 9.8 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Nup160 PF11715.8 CDJ59671.1 - 0.048 12.3 0.2 0.048 12.3 0.2 2.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF702 PF05142.12 CDJ59671.1 - 0.077 13.5 6.7 1.2 9.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) LIM_bind PF01803.16 CDJ59671.1 - 0.078 12.5 3.4 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 LIM-domain binding protein CNDH2_C PF16858.5 CDJ59671.1 - 0.12 12.2 13.3 0.05 13.5 7.9 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM60A PF15396.6 CDJ59671.1 - 0.13 12.3 6.1 0.21 11.5 1.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A BRF1 PF07741.13 CDJ59671.1 - 0.18 12.1 12.0 0.69 10.3 1.4 2.7 3 0 0 3 3 2 0 Brf1-like TBP-binding domain TFIIA PF03153.13 CDJ59671.1 - 0.22 11.5 22.7 0.3 11.0 1.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 CDJ59671.1 - 0.23 11.0 4.8 8.2 5.9 2.5 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 CDJ59671.1 - 0.39 8.8 15.3 0.71 7.9 15.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi SLC12 PF03522.15 CDJ59671.1 - 0.43 9.6 9.2 1.2 8.1 5.3 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Androgen_recep PF02166.16 CDJ59671.1 - 0.85 8.4 15.5 2.1 7.1 3.7 2.1 2 0 0 2 2 2 0 Androgen receptor DUF4746 PF15928.5 CDJ59671.1 - 1.2 8.5 12.6 0.9 8.9 8.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 CDJ59671.1 - 1.4 8.6 15.0 0.3 10.8 8.9 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF913 PF06025.12 CDJ59671.1 - 1.7 7.5 8.0 2.6 7.0 3.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4770 PF15994.5 CDJ59671.1 - 1.8 8.8 8.8 1.1 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 CDJ59671.1 - 2.8 7.9 6.9 11 6.0 3.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Afi1 PF07792.12 CDJ59671.1 - 4 7.9 15.5 8 7.0 8.3 2.6 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.13 CDJ59671.1 - 4.4 6.0 12.6 0.43 9.3 5.3 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 CDJ59671.1 - 6.8 5.9 13.2 0.86 8.8 6.3 2.2 2 0 0 2 2 2 0 Prim-pol family 5 Spt20 PF12090.8 CDJ59671.1 - 7.4 6.1 28.6 0.59 9.7 6.4 2.2 2 0 0 2 2 2 0 Spt20 family AP3D1 PF06375.11 CDJ59671.1 - 7.7 6.7 20.2 1.1 9.5 0.3 2.5 3 0 0 3 3 2 0 AP-3 complex subunit delta-1 Zip PF02535.22 CDJ59671.1 - 10 5.3 5.8 9.6 5.3 2.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Aha1_N PF09229.11 CDJ59672.1 - 3.6e-06 27.2 0.2 5.2e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal IF-2B PF01008.17 CDJ59673.1 - 3.8e-40 137.9 0.0 5.4e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family U-box PF04564.15 CDJ59676.1 - 4.5e-29 100.4 1.0 5.2e-29 100.2 1.0 1.1 1 0 0 1 1 1 1 U-box domain PRR18 PF15671.5 CDJ59676.1 - 0.019 14.8 0.4 0.022 14.6 0.4 1.0 1 0 0 1 1 1 0 Proline-rich protein family 18 DUF1293 PF06950.11 CDJ59676.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Apt1 PF10351.9 CDJ59683.1 - 0.057 12.3 31.9 0.057 12.3 20.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain MDFI PF15316.6 CDJ59683.1 - 0.13 12.3 23.0 0.16 12.1 2.4 2.8 3 0 0 3 3 3 0 MyoD family inhibitor PAP1 PF08601.10 CDJ59683.1 - 0.2 11.3 39.5 0.17 11.6 24.3 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 DUF572 PF04502.13 CDJ59683.1 - 0.25 10.9 18.8 0.9 9.1 9.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 CDJ59683.1 - 0.31 10.6 16.4 0.076 12.6 10.3 2.1 2 0 0 2 2 2 0 PPP4R2 DUF5321 PF17254.2 CDJ59683.1 - 4.4 6.7 8.5 0.28 10.6 1.7 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5321) SLC12 PF03522.15 CDJ59683.1 - 6.1 5.8 14.3 0.97 8.4 5.6 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Staphylokinase PF02821.16 CDJ59685.1 - 0.033 14.6 0.5 0.074 13.5 0.0 1.7 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family Transglut_core PF01841.19 CDJ59685.1 - 0.051 14.0 0.3 0.16 12.4 0.3 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Methyltransf_28 PF02636.17 CDJ59686.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2829 PF11195.8 CDJ59686.1 - 0.12 12.7 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) Rhomboid PF01694.22 CDJ59687.1 - 1.5e-29 103.0 8.5 1.5e-29 103.0 8.5 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 CDJ59687.1 - 0.083 13.5 0.7 0.083 13.5 0.7 2.5 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) TraS PF10624.9 CDJ59687.1 - 0.12 12.3 0.9 0.22 11.4 0.3 1.8 1 1 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS TrmB PF01978.19 CDJ59688.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RRM_1 PF00076.22 CDJ59689.1 - 3.3e-16 58.8 0.0 4.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ59689.1 - 0.013 15.6 0.0 0.057 13.6 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 CDJ59689.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sas10 PF09368.10 CDJ59691.1 - 5.1e-23 81.3 7.7 5.1e-23 81.3 7.7 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CDJ59691.1 - 9.2e-19 67.9 1.9 9.2e-19 67.9 1.9 2.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Methyltransf_8 PF05148.15 CDJ59693.1 - 8e-76 254.7 0.0 1.1e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CDJ59693.1 - 1.8e-08 34.9 0.9 1e-07 32.5 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ59693.1 - 4.3e-06 27.3 0.3 0.00011 22.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ59693.1 - 0.00012 21.9 0.0 0.0034 17.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ59693.1 - 0.03 15.0 1.2 9.5 7.0 0.0 2.9 3 1 1 4 4 4 0 Methyltransferase domain Ubie_methyltran PF01209.18 CDJ59693.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDJ59693.1 - 0.089 12.6 0.1 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain RNA_pol_Rpb1_5 PF04998.17 CDJ59695.1 - 2.8e-28 99.1 0.2 2.8e-28 99.1 0.2 2.2 1 1 1 2 2 1 1 RNA polymerase Rpb1, domain 5 TFIIA PF03153.13 CDJ59695.1 - 0.00016 21.8 49.9 0.00016 21.8 49.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit UPF0564 PF10595.9 CDJ59695.1 - 0.0029 16.7 34.3 0.0039 16.3 34.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 PAT1 PF09770.9 CDJ59695.1 - 0.0029 16.0 34.6 0.0029 16.0 34.6 1.3 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 CDJ59695.1 - 0.011 14.3 24.1 0.018 13.6 24.1 1.2 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 CDJ59695.1 - 0.03 12.9 25.6 0.038 12.6 25.6 1.1 1 0 0 1 1 1 0 Utp14 protein LEA_3 PF03242.13 CDJ59695.1 - 0.1 13.3 0.2 0.1 13.3 0.2 3.5 3 1 0 3 3 1 0 Late embryogenesis abundant protein Membralin PF09746.9 CDJ59695.1 - 0.21 10.6 13.6 0.093 11.7 11.0 1.6 2 0 0 2 2 2 0 Tumour-associated protein Zip PF02535.22 CDJ59695.1 - 0.68 9.1 15.8 0.056 12.7 9.2 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4175 PF13779.6 CDJ59695.1 - 0.85 7.5 50.1 1.1 7.1 50.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase_fungal PF17667.1 CDJ59695.1 - 1.5 7.5 12.6 0.26 10.0 7.8 1.9 2 0 0 2 2 2 0 Fungal protein kinase Radical_SAM_N PF08497.10 CDJ59695.1 - 1.5 8.0 8.7 2.7 7.2 8.7 1.4 1 0 0 1 1 1 0 Radical SAM N-terminal Rrn6 PF10214.9 CDJ59695.1 - 2.6 6.4 37.0 3.9 5.8 37.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PTPRCAP PF15713.5 CDJ59695.1 - 3 8.1 30.8 0.21 11.9 25.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NARP1 PF12569.8 CDJ59695.1 - 3.1 6.6 21.9 5.5 5.8 21.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DAG_kinase_N PF14513.6 CDJ59695.1 - 3.9 7.7 27.9 1.4 9.1 21.9 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Asp-B-Hydro_N PF05279.11 CDJ59695.1 - 3.9 7.5 18.2 6.4 6.8 18.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.6 CDJ59695.1 - 7.9 6.4 37.9 2.8 7.8 34.9 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Kinase-like PF14531.6 CDJ59696.1 - 4.4e-08 32.8 0.0 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 CDJ59696.1 - 0.0053 16.2 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ATP-synt_ab PF00006.25 CDJ59697.1 - 3.4e-26 92.2 0.0 4.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CDJ59697.1 - 6e-21 74.5 0.0 2.3e-10 40.4 0.0 2.3 1 1 1 2 2 2 2 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CDJ59697.1 - 1.8e-09 38.0 0.1 3.4e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Med3 PF11593.8 CDJ59698.1 - 0.23 10.6 2.6 0.31 10.2 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 CDJ59701.1 - 7.1e-47 160.0 0.0 1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59701.1 - 5.2e-37 127.5 0.0 7.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDJ59701.1 - 0.014 14.3 0.3 0.027 13.4 0.3 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CDJ59701.1 - 0.019 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDJ59701.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ59701.1 - 1.4 7.6 4.1 4.9 5.8 0.0 2.4 2 1 0 2 2 2 0 Fungal protein kinase Actin PF00022.19 CDJ59702.1 - 2.5e-144 480.9 0.0 1.1e-143 478.8 0.0 1.7 1 1 0 1 1 1 1 Actin ACDC PF14733.6 CDJ59703.1 - 3.5e-18 65.7 1.0 5.1e-18 65.2 1.0 1.2 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ59704.1 - 0.0033 17.6 0.8 0.0059 16.8 0.8 1.4 1 0 0 1 1 1 1 AP2 domain MRP-L46 PF11788.8 CDJ59705.1 - 5 7.9 8.5 35 5.1 8.6 2.2 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Lipase_3 PF01764.25 CDJ59707.1 - 5.7e-17 61.9 0.0 8.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ59707.1 - 0.012 16.2 0.5 0.012 16.2 0.5 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ59707.1 - 0.012 14.8 0.3 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cutinase PF01083.22 CDJ59707.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.8 CDJ59707.1 - 0.22 11.1 0.0 0.5 9.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) MA3 PF02847.17 CDJ59709.1 - 3.8e-29 100.9 1.6 1.2e-09 38.1 0.0 3.2 3 0 0 3 3 3 3 MA3 domain PARP PF00644.20 CDJ59710.1 - 2.4e-10 40.3 0.0 2.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Pex16 PF08610.10 CDJ59711.1 - 1.3e-32 113.3 1.1 2.2e-32 112.5 1.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Sec7 PF01369.20 CDJ59712.1 - 7.9e-66 221.2 0.0 1.2e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDJ59712.1 - 6.7e-14 52.1 0.1 3.2e-13 49.9 0.1 2.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ComGF PF15980.5 CDJ59712.1 - 0.13 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Putative Competence protein ComGF ASH PF15780.5 CDJ59713.1 - 6e-06 26.4 3.7 0.084 13.1 0.0 6.3 7 0 0 7 7 7 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ59713.1 - 0.00037 20.6 0.3 0.048 13.8 0.0 3.7 4 0 0 4 4 4 1 Flagellar-associated PapD-like RcsF PF16358.5 CDJ59713.1 - 0.082 13.0 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 RcsF lipoprotein PAZ PF02170.22 CDJ59714.1 - 6.6e-09 35.7 0.0 3.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.17 CDJ59714.1 - 4e-08 32.9 0.0 3.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Piwi domain WGG PF10273.9 CDJ59715.1 - 6.3e-10 39.6 2.2 6.8e-10 39.5 0.7 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 CDJ59715.1 - 0.0082 16.3 0.2 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TPR_2 PF07719.17 CDJ59716.1 - 1.3e-11 43.7 10.9 0.00091 19.2 0.3 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ59716.1 - 9.9e-09 34.7 10.8 0.01 15.6 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ59716.1 - 5.7e-05 22.7 2.8 0.015 15.0 0.2 3.0 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 CDJ59716.1 - 0.038 14.2 4.2 0.061 13.5 1.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDJ59716.1 - 0.038 14.0 1.1 0.11 12.5 1.1 1.8 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_12 PF13424.6 CDJ59716.1 - 0.067 13.5 0.1 0.067 13.5 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ59716.1 - 0.26 11.6 7.7 0.29 11.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ59716.1 - 0.53 11.3 11.4 0.71 10.9 0.3 5.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ59716.1 - 1 9.3 9.6 2.3 8.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.19 CDJ59718.1 - 0.0087 16.0 27.4 0.13 12.2 14.7 3.9 2 1 0 2 2 2 1 SPX domain CstA_5TM PF13722.6 CDJ59718.1 - 0.031 14.6 0.3 0.17 12.2 0.3 2.3 1 0 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA Pex14_N PF04695.13 CDJ59719.1 - 0.005 17.5 18.8 0.0061 17.2 18.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM76 PF16046.5 CDJ59719.1 - 0.091 12.1 10.7 0.092 12.1 10.7 1.0 1 0 0 1 1 1 0 FAM76 protein Spt20 PF12090.8 CDJ59719.1 - 0.13 11.8 26.3 0.15 11.7 26.3 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ59719.1 - 0.2 11.6 27.0 0.23 11.4 27.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ59719.1 - 0.22 10.5 20.2 0.26 10.2 20.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 CDJ59719.1 - 0.36 11.2 11.1 0.37 11.2 11.1 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like MMR1 PF08505.10 CDJ59719.1 - 0.53 10.5 13.0 0.54 10.5 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PTPRCAP PF15713.5 CDJ59719.1 - 0.78 10.0 13.2 0.95 9.8 13.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4718 PF15842.5 CDJ59719.1 - 1.1 9.0 6.8 1.3 8.8 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) FAM176 PF14851.6 CDJ59719.1 - 1.6 8.4 5.4 1.9 8.1 5.4 1.1 1 0 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.13 CDJ59719.1 - 1.8 8.3 9.5 1.8 8.3 9.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tim54 PF11711.8 CDJ59719.1 - 2.5 6.8 10.2 2.5 6.8 10.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 CDJ59719.1 - 2.8 6.6 10.1 2.6 6.7 10.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 CDJ59719.1 - 3.1 6.3 10.0 3.1 6.2 10.0 1.0 1 0 0 1 1 1 0 Macoilin family BRF1 PF07741.13 CDJ59719.1 - 3.1 8.2 10.3 4 7.8 10.3 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Sec62 PF03839.16 CDJ59719.1 - 3.1 7.3 6.2 3 7.3 6.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Gti1_Pac2 PF09729.9 CDJ59719.1 - 3.1 7.8 9.9 3.5 7.7 9.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 CDJ59719.1 - 3.3 6.9 7.7 3.5 6.8 7.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.14 CDJ59719.1 - 3.5 7.5 14.4 3.6 7.5 14.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SelP_N PF04592.14 CDJ59719.1 - 3.6 6.9 16.4 4.1 6.7 16.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.9 CDJ59719.1 - 3.6 5.7 20.0 3.8 5.7 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 CDJ59719.1 - 4.1 6.3 9.8 3.9 6.4 9.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4834 PF16118.5 CDJ59719.1 - 4.1 8.4 16.2 5.9 7.9 16.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 CDJ59719.1 - 4.1 5.8 15.0 4.4 5.7 15.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDHD PF02862.17 CDJ59719.1 - 4.4 7.4 10.6 4.3 7.4 10.6 1.1 1 0 0 1 1 1 0 DDHD domain TERB2 PF15101.6 CDJ59719.1 - 4.8 7.2 15.5 5.6 7.0 15.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 VIT1 PF01988.19 CDJ59719.1 - 5.1 6.9 9.2 6.4 6.6 9.2 1.1 1 0 0 1 1 1 0 VIT family Totivirus_coat PF05518.11 CDJ59719.1 - 5.3 5.0 17.0 5.8 4.8 17.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein Connexin PF00029.19 CDJ59719.1 - 5.9 6.6 8.2 5.8 6.6 8.2 1.1 1 0 0 1 1 1 0 Connexin RIC3 PF15361.6 CDJ59719.1 - 6.2 7.2 10.1 7.1 7.0 10.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ALMT PF11744.8 CDJ59719.1 - 6.2 5.5 8.8 6.5 5.5 8.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 CDJ59719.1 - 6.3 5.5 8.7 6.5 5.5 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 CDJ59719.1 - 7 5.3 6.1 6.3 5.5 6.1 1.0 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 CDJ59719.1 - 7.1 6.4 12.3 7.7 6.3 12.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spem1 PF15670.5 CDJ59719.1 - 7.3 6.1 12.7 7.8 6.0 12.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Neur_chan_memb PF02932.16 CDJ59719.1 - 7.5 6.5 10.7 7.4 6.5 10.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 CDJ59719.1 - 8 5.4 8.1 8.5 5.3 8.1 1.1 1 0 0 1 1 1 0 CLN3 protein eIF-3_zeta PF05091.12 CDJ59719.1 - 8.8 5.2 13.9 8.9 5.2 13.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Velvet PF11754.8 CDJ59719.1 - 9.1 6.1 15.1 11 5.9 15.1 1.1 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 CDJ59719.1 - 9.3 4.9 16.5 9.4 4.9 16.5 1.0 1 0 0 1 1 1 0 Presenilin AIM3 PF17096.5 CDJ59719.1 - 9.5 7.2 16.2 2.5 9.1 13.5 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 CPSF100_C PF13299.6 CDJ59719.1 - 9.8 6.3 12.2 11 6.1 12.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CDJ59720.1 - 0.007 16.4 36.5 0.01 15.9 36.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 CDJ59720.1 - 0.029 12.7 7.1 0.034 12.4 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.12 CDJ59720.1 - 0.045 12.4 26.3 0.055 12.2 26.3 1.0 1 0 0 1 1 1 0 Hamartin protein Pim PF16765.5 CDJ59720.1 - 0.076 13.2 3.1 0.17 12.1 3.1 1.6 1 0 0 1 1 1 0 Pesticin immunity protein DUF5427 PF10310.9 CDJ59720.1 - 0.14 11.1 18.2 0.19 10.7 18.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SOBP PF15279.6 CDJ59720.1 - 0.17 12.4 22.5 0.22 12.1 22.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LAP1C PF05609.12 CDJ59720.1 - 0.18 10.9 26.0 0.22 10.6 26.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAT1 PF09770.9 CDJ59720.1 - 0.18 10.0 22.1 0.21 9.8 22.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transglut_prok PF09017.10 CDJ59720.1 - 0.23 10.7 9.0 0.29 10.4 9.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase LptF_LptG PF03739.14 CDJ59720.1 - 0.36 9.6 1.8 0.42 9.4 1.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SWIM PF04434.17 CDJ59720.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.2 2 1 0 2 2 1 0 SWIM zinc finger GET2 PF08690.10 CDJ59720.1 - 3.5 7.2 20.7 4.7 6.8 20.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PCI PF01399.27 CDJ59721.1 - 0.012 16.1 0.0 0.026 15.1 0.0 1.6 1 1 0 1 1 1 0 PCI domain zf-C3HC4_3 PF13920.6 CDJ59722.1 - 0.1 12.5 1.8 0.21 11.5 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Utp14 PF04615.13 CDJ59722.1 - 1.4 7.4 58.8 0.02 13.5 8.1 2.9 2 1 0 2 2 2 0 Utp14 protein EF-hand_1 PF00036.32 CDJ59723.1 - 9.5e-12 43.6 0.9 7e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ59723.1 - 5e-11 41.6 1.0 1e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ59723.1 - 2.5e-10 40.6 9.2 9e-07 29.3 2.7 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ59723.1 - 7.6e-08 31.5 2.2 5e-05 22.6 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ59723.1 - 0.00048 19.9 1.2 0.073 12.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair HTH_31 PF13560.6 CDJ59723.1 - 0.074 13.4 0.0 0.091 13.1 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain Spt20 PF12090.8 CDJ59723.1 - 0.27 10.8 11.5 0.38 10.3 11.5 1.3 1 0 0 1 1 1 0 Spt20 family PseudoU_synth_1 PF01416.20 CDJ59724.1 - 0.0018 18.7 0.6 0.0083 16.6 0.1 2.4 2 1 1 3 3 3 1 tRNA pseudouridine synthase Caldesmon PF02029.15 CDJ59724.1 - 0.42 9.3 38.8 0.58 8.8 38.8 1.1 1 0 0 1 1 1 0 Caldesmon DUF979 PF06166.12 CDJ59724.1 - 1.3 8.2 3.5 0.46 9.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF979) EB1_binding PF05937.11 CDJ59725.1 - 1.7 9.2 8.1 9.2 6.8 2.9 2.2 2 0 0 2 2 2 0 EB-1 Binding Domain SARAF PF06682.12 CDJ59726.1 - 0.0051 16.5 1.4 0.0051 16.5 1.4 4.5 4 1 1 5 5 5 2 SOCE-associated regulatory factor of calcium homoeostasis Ant_C PF05586.11 CDJ59726.1 - 0.11 13.1 0.2 0.11 13.1 0.2 4.4 5 0 0 5 5 5 0 Anthrax receptor C-terminus region Class_IIIsignal PF04021.12 CDJ59727.1 - 0.05 13.6 0.6 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Class III signal peptide DUF2388 PF09498.10 CDJ59727.1 - 0.19 11.7 0.7 12 6.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2388) TLP-20 PF06088.11 CDJ59728.1 - 0.34 10.8 4.8 0.63 9.9 4.8 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.11 CDJ59728.1 - 1.8 8.1 8.8 0.2 11.2 4.8 1.4 2 0 0 2 2 2 0 PPP4R2 Pex14_N PF04695.13 CDJ59728.1 - 4.2 8.0 23.8 2.8 8.6 14.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region O-antigen_lig PF13425.6 CDJ59728.1 - 5 5.8 3.9 7.3 5.3 3.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ribosomal_S17e PF00833.18 CDJ59729.1 - 1.5e-24 86.2 0.4 1.8e-24 86.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 DnaJ PF00226.31 CDJ59730.1 - 6.3e-15 55.0 0.0 2.6e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain DUF2967 PF11179.8 CDJ59730.1 - 0.75 7.8 12.3 1.9 6.5 12.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2967) AAA_9 PF12781.7 CDJ59731.1 - 2.4e-13 49.8 4.9 3.9e-13 49.0 4.9 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region APG6_N PF17675.1 CDJ59731.1 - 0.0098 16.4 9.5 0.065 13.8 2.7 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region DUF3729 PF12526.8 CDJ59732.1 - 0.7 11.5 6.8 3.1 9.4 8.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) SAYSvFN PF10260.9 CDJ59734.1 - 8.9e-13 48.0 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.15 CDJ59734.1 - 1.8e-05 24.5 15.0 2.8e-05 23.9 15.0 1.3 1 0 0 1 1 1 1 SEC-C motif DUF4831 PF16115.5 CDJ59735.1 - 0.21 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) tRNA-synt_1b PF00579.25 CDJ59736.1 - 3e-32 112.1 0.5 4.3e-16 59.1 1.8 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (W and Y) SR-25 PF10500.9 CDJ59736.1 - 3.2e-05 23.7 6.0 3.2e-05 23.7 6.0 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ59736.1 - 0.0002 20.4 3.1 0.0002 20.4 3.1 4.2 4 1 0 4 4 4 1 Protein of unknown function (DUF2722) CCSAP PF15748.5 CDJ59736.1 - 0.018 15.2 4.0 0.018 15.2 4.0 2.7 3 1 0 3 3 3 0 Centriole, cilia and spindle-associated SNARE PF05739.19 CDJ59736.1 - 0.29 11.2 3.6 1.2 9.2 3.6 2.1 1 0 0 1 1 1 0 SNARE domain SMYLE_N PF18615.1 CDJ59736.1 - 3.3 7.2 12.8 0.077 12.5 3.7 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF2232 PF09991.9 CDJ59736.1 - 4.6 6.3 4.8 1.6 7.8 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Presenilin PF01080.17 CDJ59736.1 - 6 5.5 10.9 0.79 8.4 4.2 2.2 2 0 0 2 2 2 0 Presenilin DEAD PF00270.29 CDJ59737.1 - 1.3e-17 64.2 0.4 1.3e-17 64.2 0.4 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase Exonuc_VII_L PF02601.15 CDJ59737.1 - 0.0082 15.7 40.7 0.0088 15.6 29.1 2.6 2 0 0 2 2 2 2 Exonuclease VII, large subunit Tox-SHH PF15652.6 CDJ59739.1 - 6.6 7.8 8.8 0.37 11.8 1.2 2.8 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature FG-GAP PF01839.23 CDJ59741.1 - 8.1e-05 22.7 0.7 8.1e-05 22.7 0.7 1.9 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 CDJ59741.1 - 0.0048 17.5 1.3 0.52 10.9 1.7 3.1 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Hydin_ADK PF17213.3 CDJ59741.1 - 0.015 15.6 17.2 0.27 11.5 8.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Tim54 PF11711.8 CDJ59741.1 - 0.035 12.9 12.3 0.4 9.4 1.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RXT2_N PF08595.11 CDJ59741.1 - 0.042 13.9 0.7 0.042 13.9 0.7 2.7 2 1 0 2 2 1 0 RXT2-like, N-terminal CCDC53 PF10152.9 CDJ59741.1 - 0.05 14.0 1.1 0.05 14.0 1.1 2.9 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex DUF4569 PF15133.6 CDJ59741.1 - 0.11 12.3 18.8 0.71 9.5 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) DUF2072 PF09845.9 CDJ59741.1 - 0.28 11.4 11.3 1.3 9.3 1.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein Ndc1_Nup PF09531.10 CDJ59741.1 - 0.31 9.7 15.5 0.43 9.2 15.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Senescence_reg PF04520.13 CDJ59741.1 - 0.86 10.4 15.0 7.6 7.3 8.9 2.1 2 0 0 2 2 2 0 Senescence regulator RR_TM4-6 PF06459.12 CDJ59741.1 - 1.7 8.4 18.9 2 8.2 4.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ORC_WH_C PF18137.1 CDJ59741.1 - 3.4 7.7 17.3 4.1 7.5 3.6 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal FAM60A PF15396.6 CDJ59741.1 - 6.2 6.8 16.6 0.69 9.9 1.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A V_ATPase_I PF01496.19 CDJ59741.1 - 7.7 4.3 20.3 0.36 8.7 2.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MAT1 PF06391.13 CDJ59741.1 - 8.2 6.2 28.8 9.1 6.1 13.2 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Kri1_C PF12936.7 CDJ59742.1 - 0.00064 19.9 0.0 0.00084 19.5 0.0 1.1 1 0 0 1 1 1 1 KRI1-like family C-terminal Cadherin_C_2 PF16492.5 CDJ59744.1 - 0.14 12.9 0.8 0.45 11.3 0.8 2.0 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Dynamitin PF04912.14 CDJ59745.1 - 3.7e-26 92.4 2.7 4.7e-24 85.5 2.7 2.5 1 1 0 1 1 1 1 Dynamitin SlyX PF04102.12 CDJ59745.1 - 4.4 8.0 11.4 9.2 7.0 0.3 3.7 3 1 0 3 3 3 0 SlyX zf-C3HC4 PF00097.25 CDJ59746.1 - 1.4e-06 28.1 4.2 2.7e-06 27.1 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ59746.1 - 7.8e-06 25.6 5.0 1.7e-05 24.6 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDJ59746.1 - 1.6e-05 25.0 7.5 3.7e-05 23.8 7.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDJ59746.1 - 0.00014 21.9 6.2 0.00031 20.7 6.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ59746.1 - 0.00022 21.0 2.0 0.00042 20.1 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CDJ59746.1 - 0.0015 18.4 4.8 0.0044 17.0 4.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CDJ59746.1 - 0.0042 16.9 0.4 0.0087 15.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 CDJ59746.1 - 0.01 16.1 5.6 0.02 15.2 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 CDJ59746.1 - 0.016 15.1 4.7 0.032 14.1 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NP1-WLL PF11733.8 CDJ59746.1 - 0.061 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 Rsbr_N PF08678.10 CDJ59746.1 - 0.079 13.0 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Rsbr N terminal zf-RING_4 PF14570.6 CDJ59750.1 - 1.2e-19 69.8 10.6 2.1e-19 69.0 10.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDJ59750.1 - 3.6e-06 26.7 9.1 3.6e-06 26.7 9.1 1.8 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDJ59750.1 - 2.5e-05 24.0 0.0 5.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CDJ59750.1 - 0.0049 17.6 0.1 0.0049 17.6 0.1 3.3 2 0 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 CDJ59750.1 - 0.011 16.1 11.4 0.011 16.1 11.4 1.8 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 CDJ59750.1 - 0.45 10.4 11.1 1.8 8.5 4.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CDJ59750.1 - 0.57 10.1 5.0 1.1 9.2 5.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 CDJ59750.1 - 0.62 10.2 3.1 1.4 9.1 3.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.7 CDJ59750.1 - 3.4 7.8 9.6 11 6.2 9.6 1.9 1 0 0 1 1 1 0 Double zinc ribbon Radical_SAM PF04055.21 CDJ59751.1 - 2.6e-19 70.2 0.0 6.8e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 CDJ59751.1 - 3e-16 59.3 0.2 9.2e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 CDJ59751.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 TRAM domain DUF4578 PF15147.6 CDJ59751.1 - 5.2 8.0 6.3 1.4 9.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) BRF1 PF07741.13 CDJ59752.1 - 0.63 10.4 16.2 1.7 9.0 3.3 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4407 PF14362.6 CDJ59752.1 - 1.1 8.6 24.1 0.14 11.5 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) JmjC PF02373.22 CDJ59752.1 - 1.5 9.3 11.2 0.053 13.9 2.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Suf PF05843.14 CDJ59752.1 - 4.2 7.3 17.1 8.1 6.3 5.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3371 PF11851.8 CDJ59752.1 - 5.5 8.1 15.7 3.3 8.8 4.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) AAA_23 PF13476.6 CDJ59752.1 - 7.2 7.1 17.7 6.8 7.1 4.4 2.2 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 CDJ59752.1 - 7.8 6.5 11.4 12 5.8 0.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4820 PF16091.5 CDJ59752.1 - 8.8 5.6 13.3 8.3 5.7 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) SecY PF00344.20 CDJ59754.1 - 2.1e-39 135.6 5.0 2.3e-39 135.5 5.0 1.0 1 0 0 1 1 1 1 SecY translocase QCR10 PF09796.9 CDJ59754.1 - 0.11 12.6 0.4 3.1 7.9 0.1 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AhpC-TSA PF00578.21 CDJ59755.1 - 2e-30 105.2 0.0 2.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDJ59755.1 - 3e-12 46.5 0.0 3.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDJ59755.1 - 4.3e-10 39.3 0.2 6.6e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDJ59755.1 - 0.0076 16.4 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme GSHPx PF00255.19 CDJ59755.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase SET PF00856.28 CDJ59757.1 - 3.4e-06 27.5 0.0 1.9e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 SET domain Peptidase_U4 PF03419.13 CDJ59758.1 - 0.42 9.9 4.2 0.66 9.2 4.2 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Gamma-thionin PF00304.20 CDJ59758.1 - 0.44 10.8 3.2 3.5 8.0 0.6 3.3 3 0 0 3 3 3 0 Gamma-thionin family DUF4512 PF14975.6 CDJ59758.1 - 2.8 8.8 11.5 5.2 7.9 0.4 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4512) Phage_holin_3_6 PF07332.11 CDJ59761.1 - 0.011 15.7 0.7 0.016 15.2 0.1 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1206 PF06724.11 CDJ59761.1 - 0.095 12.8 0.1 0.095 12.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) EMP70 PF02990.16 CDJ59762.1 - 1.4e-134 449.6 11.4 7.2e-75 252.6 0.0 3.2 1 1 1 2 2 2 2 Endomembrane protein 70 ER_lumen_recept PF00810.18 CDJ59763.1 - 2e-12 48.2 0.3 3e-12 47.6 0.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DctQ PF04290.12 CDJ59763.1 - 0.019 14.9 0.5 0.026 14.4 0.5 1.4 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component ATG7_N PF16420.5 CDJ59763.1 - 0.043 13.4 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Ribosomal_L14e PF01929.17 CDJ59764.1 - 1.9e-30 105.2 4.4 2.5e-30 104.8 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CDJ59764.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KOW motif PPTA PF01239.22 CDJ59765.1 - 2.5e-20 71.5 7.9 3e-05 23.6 0.1 5.7 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Presenilin PF01080.17 CDJ59765.1 - 0.014 14.2 4.4 0.017 13.9 2.7 1.7 2 0 0 2 2 2 0 Presenilin DUF2203 PF09969.9 CDJ59765.1 - 0.099 13.4 1.0 0.3 11.8 1.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SPX PF03105.19 CDJ59765.1 - 0.2 11.6 6.2 0.61 9.9 4.1 2.2 2 0 0 2 2 2 0 SPX domain DUF3959 PF13105.6 CDJ59765.1 - 0.22 11.0 0.4 0.47 9.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) LisH_TPL PF17814.1 CDJ59766.1 - 0.075 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain ORC_WH_C PF18137.1 CDJ59766.1 - 1.4 9.0 6.5 4.4 7.4 0.2 3.3 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal DUF2408 PF10303.9 CDJ59767.1 - 0.035 14.7 0.9 0.057 14.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Syntaxin-6_N PF09177.11 CDJ59767.1 - 0.038 14.5 0.7 0.53 10.9 0.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PHM7_cyt PF14703.6 CDJ59767.1 - 0.11 12.8 2.9 0.46 10.7 0.6 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Hrs_helical PF12210.8 CDJ59767.1 - 0.15 12.6 2.9 3.7 8.1 0.0 3.3 2 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TSNAXIP1_N PF15739.5 CDJ59767.1 - 0.84 10.0 0.1 0.84 10.0 0.1 2.6 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus MFS_1 PF07690.16 CDJ59768.1 - 9.9e-08 31.3 1.6 9.9e-08 31.3 1.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Lipoprotein_18 PF06804.11 CDJ59768.1 - 0.09 11.8 4.4 0.22 10.5 4.4 1.7 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Ribosomal_L13 PF00572.18 CDJ59769.1 - 1.6e-37 128.5 0.0 2.4e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Prot_ATP_ID_OB PF16450.5 CDJ59770.1 - 3.4e-10 39.7 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain Prot_ATP_OB_N PF17758.1 CDJ59770.1 - 0.052 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PDEase_I PF00233.19 CDJ59771.1 - 2.5e-59 200.9 0.0 3.7e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CAP_C PF08603.11 CDJ59773.1 - 1.7e-51 173.9 3.2 1.9e-51 173.8 3.2 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CDJ59773.1 - 5e-06 26.2 1.5 6.9e-06 25.8 1.5 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C HlyD_3 PF13437.6 CDJ59773.1 - 0.1 13.3 0.1 4.4 8.1 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein DUF918 PF06033.11 CDJ59773.1 - 0.12 12.4 0.6 0.56 10.2 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Glucan_synthase PF02364.15 CDJ59777.1 - 2.3e-138 462.7 4.3 9.3e-107 358.2 4.0 2.5 2 0 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CDJ59777.1 - 9.3e-13 48.6 5.3 2.3e-10 40.9 5.3 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_trans_2_3 PF13632.6 CDJ59777.1 - 0.015 15.2 0.2 0.015 15.2 0.2 2.6 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Methyltrn_RNA_3 PF02598.17 CDJ59781.1 - 4.9e-24 85.3 0.0 5.6e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 CDJ59781.1 - 0.057 13.6 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 SpoU rRNA Methylase family Rav1p_C PF12234.8 CDJ59782.1 - 6.1e-24 84.4 7.7 1.7e-13 49.9 0.5 4.9 4 0 0 4 4 4 4 RAVE protein 1 C terminal ADP_ribosyl_GH PF03747.14 CDJ59785.1 - 0.14 11.9 11.1 0.15 11.7 11.1 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Activator_LAG-3 PF11498.8 CDJ59785.1 - 0.21 10.5 27.6 0.23 10.4 27.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 IHABP4_N PF16174.5 CDJ59785.1 - 0.72 10.4 24.5 0.84 10.2 24.5 1.0 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal LCIB_C_CA PF18599.1 CDJ59785.1 - 0.96 8.7 9.9 1.2 8.4 9.9 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4569 PF15133.6 CDJ59785.1 - 1.5 8.5 16.0 1.6 8.4 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) PAF-AH_p_II PF03403.13 CDJ59785.1 - 2.4 6.6 9.7 2.9 6.3 9.7 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RskA PF10099.9 CDJ59785.1 - 3.6 7.9 23.0 13 6.0 23.0 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 CDJ59785.1 - 5.9 5.7 17.9 6.2 5.7 17.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HemX PF04375.14 CDJ59785.1 - 6.2 6.0 27.4 7.5 5.7 27.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S15 PF02129.18 CDJ59785.1 - 8.8 5.8 11.9 9.9 5.7 11.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GREB1 PF15782.5 CDJ59788.1 - 7.3 3.6 23.5 9.4 3.2 23.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EIF4E-T PF10477.9 CDJ59789.1 - 0.016 14.1 9.3 0.028 13.3 9.3 1.5 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Activator_LAG-3 PF11498.8 CDJ59789.1 - 1 8.3 39.1 1.6 7.6 38.3 1.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PAT1 PF09770.9 CDJ59789.1 - 1.9 6.7 25.2 2.4 6.3 25.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hydrolase_4 PF12146.8 CDJ59791.1 - 7.2e-23 81.1 0.0 1.9e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDJ59791.1 - 3.9e-07 30.9 0.3 3.9e-07 30.9 0.3 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDJ59791.1 - 0.0013 18.5 0.0 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDJ59791.1 - 0.0024 17.8 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ59791.1 - 0.013 15.0 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF900 PF05990.12 CDJ59791.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 CDJ59791.1 - 0.048 13.6 0.0 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Cutinase DUF726 PF05277.12 CDJ59791.1 - 2.2 7.1 5.3 0.95 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF726) Kin17_mid PF10357.9 CDJ59794.1 - 2.3e-41 140.6 1.9 2.3e-41 140.6 1.9 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDJ59794.1 - 2.8e-21 75.4 1.2 5.4e-21 74.5 1.2 1.5 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CDJ59794.1 - 0.0078 16.6 4.0 0.019 15.4 4.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NdhS PF11623.8 CDJ59794.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S YolD PF08863.10 CDJ59794.1 - 0.25 11.4 3.1 0.74 9.9 3.1 1.9 1 0 0 1 1 1 0 YolD-like protein zf-C2H2_jaz PF12171.8 CDJ59794.1 - 0.38 11.1 7.3 0.14 12.5 4.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_6 PF12774.7 CDJ59797.1 - 9e-119 396.3 3.1 9.3e-118 392.9 0.1 3.1 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ59797.1 - 2.3e-82 277.2 2.1 2.3e-82 277.2 2.1 3.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 CDJ59797.1 - 8.9e-58 195.9 1.8 2e-57 194.8 1.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CDJ59797.1 - 7.4e-50 169.1 2.5 2.2e-49 167.5 0.0 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDJ59797.1 - 3.3e-49 167.5 0.0 1.1e-48 165.8 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ59797.1 - 2.8e-44 151.6 1.3 1e-43 149.7 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ59797.1 - 4.8e-29 100.9 0.0 9.6e-28 96.7 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 CDJ59797.1 - 3.2e-27 95.2 0.0 1.4e-14 54.1 0.0 4.5 3 1 1 4 4 4 3 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 CDJ59797.1 - 1.5e-15 57.4 0.0 5.2e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_11 PF18198.1 CDJ59797.1 - 7e-15 55.2 0.0 2.2e-14 53.6 0.0 1.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ59797.1 - 5.2e-07 29.7 4.5 0.31 11.0 0.0 5.3 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDJ59797.1 - 7e-05 23.1 1.4 3 8.1 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 CDJ59797.1 - 0.00011 22.6 0.4 0.46 10.9 0.0 4.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_1 PF17857.1 CDJ59797.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 CDJ59797.1 - 0.017 14.5 2.9 1 8.7 0.1 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 CDJ59797.1 - 0.073 12.4 1.0 16 4.8 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 CDJ59797.1 - 0.11 12.9 0.4 24 5.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase MPS2 PF17060.5 CDJ59797.1 - 4.8 6.3 6.9 0.32 10.2 0.7 2.0 2 0 0 2 2 2 0 Monopolar spindle protein 2 Tubulin PF00091.25 CDJ59798.1 - 1.3e-33 116.9 0.0 5.1e-25 88.8 0.0 2.4 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 CDJ59798.1 - 0.0015 18.8 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain RRM_1 PF00076.22 CDJ59799.1 - 1.1e-29 102.0 0.0 1.1e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ59799.1 - 1.7e-06 28.0 0.1 1.7e-05 24.8 0.1 2.5 2 2 0 2 2 2 1 RNA recognition motif TFIIA PF03153.13 CDJ59802.1 - 0.00034 20.7 6.2 0.00034 20.7 6.2 3.5 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ59802.1 - 0.0047 17.2 7.5 0.0047 17.2 7.5 7.2 4 1 3 7 7 7 2 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ59802.1 - 0.034 13.7 0.3 0.034 13.7 0.3 4.0 2 1 1 3 3 3 0 Exonuclease VII, large subunit DUF2722 PF10846.8 CDJ59803.1 - 0.0013 17.8 14.2 0.0013 17.8 14.2 11.9 7 3 2 10 10 10 3 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ59803.1 - 0.002 18.5 1.1 0.002 18.5 1.1 9.5 4 4 3 7 7 7 2 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ59805.1 - 0.00039 19.8 0.0 0.00039 19.8 0.0 12.4 10 3 1 12 12 12 5 Sin-like protein conserved region RNA_pol_Rpb1_5 PF04998.17 CDJ59806.1 - 6.4e-29 101.2 0.0 8.7e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RAP PF08373.10 CDJ59808.1 - 2.1e-10 40.5 0.0 5.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 RAP domain DUF3654 PF12376.8 CDJ59809.1 - 0.25 11.5 3.0 2 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) Cullin_Nedd8 PF10557.9 CDJ59812.1 - 0.08 13.0 1.3 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Cullin protein neddylation domain DUF1700 PF08006.11 CDJ59812.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Surface_antigen PF11054.8 CDJ59814.1 - 1.7e-12 47.6 0.4 3.2e-12 46.7 0.4 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen AP2 PF00847.20 CDJ59816.1 - 2.5e-06 27.6 1.6 0.0072 16.5 0.7 2.3 2 0 0 2 2 2 2 AP2 domain DUF588 PF04535.12 CDJ59816.1 - 4 7.2 5.0 8.6 6.1 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) tRNA-synt_2b PF00587.25 CDJ59817.1 - 1.2e-22 80.8 0.0 2.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDJ59817.1 - 1.7e-19 69.8 0.0 8.5e-19 67.5 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 CDJ59817.1 - 2.2e-19 69.7 0.2 4.5e-19 68.7 0.1 1.6 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain ProRS-C_1 PF09180.11 CDJ59817.1 - 6.7e-19 67.9 0.2 1.6e-18 66.6 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF4263 PF14082.6 CDJ59817.1 - 0.059 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DUF1415 PF07209.12 CDJ59817.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) DUF726 PF05277.12 CDJ59819.1 - 3.5e-98 328.7 6.0 5.8e-72 242.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Cutinase PF01083.22 CDJ59819.1 - 0.043 13.8 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 CDJ59819.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Bromodomain PF00439.25 CDJ59820.1 - 1.4e-33 114.8 0.0 3.7e-18 65.4 0.0 2.6 2 0 0 2 2 2 2 Bromodomain AZUL PF16558.5 CDJ59820.1 - 0.59 10.4 0.0 0.59 10.4 0.0 3.1 3 0 0 3 3 3 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HAP1_N PF04849.13 CDJ59820.1 - 1.4 8.0 17.9 0.51 9.5 10.8 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SR-25 PF10500.9 CDJ59821.1 - 0.96 9.0 8.6 1 8.9 8.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2076 PF09849.9 CDJ59821.1 - 5.5 6.9 11.1 7.2 6.6 11.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) AP2 PF00847.20 CDJ59823.1 - 7e-09 35.8 4.9 0.00013 22.1 1.1 2.6 2 0 0 2 2 2 2 AP2 domain Spt20 PF12090.8 CDJ59823.1 - 0.00092 18.9 2.8 0.00092 18.9 2.8 5.2 2 1 2 5 5 5 1 Spt20 family ACDC PF14733.6 CDJ59823.1 - 0.0018 18.5 0.2 0.0018 18.5 0.2 3.2 3 0 0 3 3 3 1 AP2-coincident C-terminal SARAF PF06682.12 CDJ59823.1 - 0.98 9.0 48.9 0.16 11.6 29.3 3.1 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ETRAMP PF09716.10 CDJ59823.1 - 1.3 9.1 4.6 4.5 7.4 0.5 3.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Caldesmon PF02029.15 CDJ59823.1 - 8.4 5.0 42.4 1.2 7.8 35.8 2.1 2 0 0 2 2 2 0 Caldesmon GAF PF01590.26 CDJ59824.1 - 1.2e-07 32.4 0.3 3.8e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 CDJ59824.1 - 1.8e-05 25.1 0.1 6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 GAF domain Neil1-DNA_bind PF09292.10 CDJ59824.1 - 0.16 12.0 1.3 0.37 10.8 0.4 2.0 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind Phosphorylase PF00343.20 CDJ59825.1 - 1.5e-260 866.4 0.0 1.8e-260 866.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Aminotran_5 PF00266.19 CDJ59827.1 - 1.8e-33 116.0 0.0 2e-30 106.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Spt20 PF12090.8 CDJ59830.1 - 2.8 7.5 11.5 6.2 6.4 11.5 1.5 1 0 0 1 1 1 0 Spt20 family DNA_pol_A PF00476.20 CDJ59831.1 - 4.7e-77 259.6 0.7 2.7e-50 171.5 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase family A 5_3_exonuc PF01367.20 CDJ59831.1 - 7.7e-09 36.0 0.0 2.4e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CDJ59831.1 - 6.6e-05 22.9 0.0 0.0014 18.6 0.0 2.5 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain CLP_protease PF00574.23 CDJ59831.1 - 1.5 8.7 6.7 18 5.2 1.9 2.7 2 0 0 2 2 2 0 Clp protease SecY PF00344.20 CDJ59835.1 - 1.5e-27 96.7 8.5 1.7e-27 96.5 8.5 1.0 1 0 0 1 1 1 1 SecY translocase RRM_1 PF00076.22 CDJ59836.1 - 3.9e-30 103.5 0.0 1.7e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ59836.1 - 6.4e-05 22.9 0.0 0.25 11.4 0.0 2.4 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 CDJ59836.1 - 0.00035 20.6 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF3343 PF11823.8 CDJ59836.1 - 0.062 12.8 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) WD40 PF00400.32 CDJ59837.1 - 0.00018 22.3 2.3 9.4 7.3 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat SR-25 PF10500.9 CDJ59837.1 - 9.5 5.8 25.5 0.6 9.7 19.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Guanylate_cyc PF00211.20 CDJ59839.1 - 1.3e-12 47.8 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 CDJ59840.1 - 5e-06 26.3 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TipAS PF07739.13 CDJ59843.1 - 0.086 13.4 0.5 5.8 7.5 0.2 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RRP7 PF12923.7 CDJ59843.1 - 0.16 12.1 1.3 0.32 11.1 1.3 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain VasL PF12486.8 CDJ59845.1 - 0.22 11.4 2.2 0.49 10.3 0.4 2.5 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL Pentapeptide PF00805.22 CDJ59846.1 - 1.3e-08 34.3 0.1 0.011 15.4 0.0 2.5 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) DUF296 PF03479.15 CDJ59846.1 - 0.51 10.7 9.5 3.9e+02 1.5 9.5 3.3 1 1 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain Aminotran_5 PF00266.19 CDJ59848.1 - 4.9e-18 65.2 0.0 6.5e-16 58.2 0.0 3.2 1 1 0 1 1 1 1 Aminotransferase class-V Prok-RING_1 PF14446.6 CDJ59849.1 - 7.3e-05 22.6 1.2 7.3e-05 22.6 1.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 CDJ59849.1 - 0.0043 16.9 2.1 0.0043 16.9 2.1 4.0 4 0 0 4 4 4 1 PHD-finger Syja_N PF02383.18 CDJ59851.1 - 5.1e-31 108.2 0.0 5.4e-28 98.2 0.0 3.9 3 1 0 3 3 3 2 SacI homology domain PX PF00787.24 CDJ59852.1 - 4.1e-15 55.8 0.0 1.3e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 PX domain Ras PF00071.22 CDJ59853.1 - 8.3e-17 61.2 0.0 2.1e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ59853.1 - 4.7e-09 36.5 0.0 1.5e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ59853.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family Methyltransf_25 PF13649.6 CDJ59854.1 - 3e-06 27.8 0.0 5.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ59854.1 - 0.0028 17.5 0.1 0.0042 16.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDJ59854.1 - 0.055 13.3 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Orexin PF02072.15 CDJ59854.1 - 0.14 12.1 2.0 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Prepro-orexin MetW PF07021.12 CDJ59854.1 - 0.2 11.2 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Macoilin PF09726.9 CDJ59855.1 - 9.1e-07 27.8 3.8 1.4e-06 27.2 3.8 1.3 1 0 0 1 1 1 1 Macoilin family SR-25 PF10500.9 CDJ59855.1 - 0.00081 19.1 50.1 0.0045 16.6 25.6 2.3 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein PAP1 PF08601.10 CDJ59855.1 - 0.24 11.1 27.5 0.33 10.6 27.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 CDJ59855.1 - 0.75 8.6 17.1 1.2 7.9 17.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ59855.1 - 5 5.3 8.4 9.4 4.4 8.4 1.5 1 0 0 1 1 1 0 CDC45-like protein Surface_antigen PF11054.8 CDJ59856.1 - 1.4e-06 28.2 0.2 1.4e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen LBP_M PF17385.2 CDJ59858.1 - 0.039 13.5 0.5 0.26 10.8 0.5 2.1 1 1 0 1 1 1 0 Lacto-N-biose phosphorylase central domain H2O2_YaaD PF03883.14 CDJ59858.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Peroxide stress protein YaaA SH3_17 PF18350.1 CDJ59858.1 - 0.053 13.4 1.2 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Restriction endonuclease SH3 domain Hamartin PF04388.12 CDJ59859.1 - 0.18 10.4 15.5 0.21 10.2 15.5 1.0 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 CDJ59859.1 - 0.79 8.5 10.3 1 8.1 10.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDJ59859.1 - 2.1 8.2 10.3 2.6 7.9 10.3 1.2 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 CDJ59859.1 - 2.3 7.0 8.9 2.6 6.8 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CDJ59861.1 - 0.0076 15.0 3.4 0.01 14.6 3.4 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 CDJ59861.1 - 0.057 12.3 8.2 0.091 11.6 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 CDJ59861.1 - 0.079 11.8 3.8 0.14 11.0 3.8 1.4 1 0 0 1 1 1 0 Otopetrin Slu7 PF11708.8 CDJ59861.1 - 0.088 12.5 16.3 0.92 9.2 9.7 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF719 PF05334.13 CDJ59861.1 - 0.22 11.7 11.5 3 8.0 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Proton_antipo_C PF01010.19 CDJ59861.1 - 0.4 10.3 0.7 0.58 9.7 0.7 1.3 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DUF853 PF05872.12 CDJ59861.1 - 0.55 8.8 14.5 1.2 7.6 4.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) SelP_N PF04592.14 CDJ59861.1 - 0.68 9.3 35.3 0.19 11.1 20.3 2.6 3 0 0 3 3 3 0 Selenoprotein P, N terminal region MCU PF04678.13 CDJ59861.1 - 0.75 9.9 9.5 6.6 6.8 5.6 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RRP36 PF06102.12 CDJ59861.1 - 0.91 9.5 18.1 1.4 8.8 2.1 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 RPA43_OB PF17875.1 CDJ59861.1 - 1 10.0 14.0 1.1 9.9 3.3 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I SRP9-21 PF05486.12 CDJ59861.1 - 1.1 9.7 6.5 11 6.5 2.8 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) FAM176 PF14851.6 CDJ59861.1 - 1.1 8.9 11.6 3.5 7.3 4.7 2.6 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.10 CDJ59861.1 - 1.2 9.2 14.1 1.3 9.1 6.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MDM31_MDM32 PF08118.11 CDJ59861.1 - 1.8 7.1 10.1 0.14 10.8 2.5 2.0 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2828 PF11443.8 CDJ59861.1 - 2.4 6.1 11.5 4.1 5.4 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SLC12 PF03522.15 CDJ59861.1 - 3.3 6.6 16.6 5.7 5.8 16.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PPDK_N PF01326.19 CDJ59863.1 - 1.6e-09 37.5 0.0 0.048 12.9 0.0 3.9 4 0 0 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain IBR PF01485.21 CDJ59864.1 - 1e-10 41.6 8.5 1.2e-09 38.2 6.6 3.2 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 CDJ59864.1 - 6.3 6.9 7.4 5.9 7.0 4.8 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain DEAD PF00270.29 CDJ59865.1 - 9.7e-27 93.9 0.0 2.3e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ59865.1 - 1.1e-22 80.5 0.0 2.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4351 PF14261.6 CDJ59865.1 - 0.027 14.5 1.9 0.11 12.5 1.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) EF-hand_7 PF13499.6 CDJ59866.1 - 8.9e-13 48.5 0.1 2.7e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ59866.1 - 4.5e-11 41.8 0.0 0.00014 21.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDJ59866.1 - 3.6e-09 35.5 0.0 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CDJ59866.1 - 5.5e-06 26.6 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ59866.1 - 4e-05 23.4 0.0 0.059 13.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDJ59866.1 - 0.0038 16.7 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 EF hand GPHH PF16905.5 CDJ59866.1 - 0.056 13.2 0.1 17 5.3 0.0 3.0 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated HLH PF00010.26 CDJ59866.1 - 0.13 12.2 2.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain BRCT_2 PF16589.5 CDJ59867.1 - 0.00018 21.9 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain UPF0160 PF03690.13 CDJ59868.1 - 5.1e-81 272.8 3.4 6e-50 170.7 0.1 3.6 2 2 0 2 2 2 2 Uncharacterised protein family (UPF0160) HOOK PF05622.12 CDJ59869.1 - 1.8e-05 23.1 7.7 1.8e-05 23.1 7.7 2.8 1 1 2 3 3 3 1 HOOK protein RILP PF11461.8 CDJ59869.1 - 0.00034 20.8 1.8 2.9 8.2 0.0 4.2 4 0 0 4 4 4 1 Rab interacting lysosomal protein DUF2353 PF09789.9 CDJ59869.1 - 0.0012 18.3 15.8 2 7.7 14.1 2.9 1 1 2 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.18 CDJ59869.1 - 0.0022 18.2 26.2 0.035 14.3 1.1 5.8 6 0 0 6 6 6 1 Homeobox associated leucine zipper YabA PF06156.13 CDJ59869.1 - 0.0063 17.1 11.1 0.16 12.6 0.7 3.5 2 2 2 4 4 4 2 Initiation control protein YabA DUF1202 PF06717.11 CDJ59869.1 - 0.0066 15.9 1.0 1.4 8.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1202) TSC22 PF01166.18 CDJ59869.1 - 0.011 16.0 12.9 2.7 8.4 0.2 4.7 4 1 1 5 5 5 0 TSC-22/dip/bun family ATG16 PF08614.11 CDJ59869.1 - 0.02 15.1 31.9 1.8 8.8 6.1 4.2 2 2 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 CDJ59869.1 - 0.024 14.4 31.4 1.9 8.3 2.3 5.4 4 2 1 5 5 5 0 Septum formation initiator GAS PF13851.6 CDJ59869.1 - 0.056 12.8 23.8 0.34 10.2 2.3 3.7 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.6 CDJ59869.1 - 0.067 13.5 18.5 0.93 9.8 0.3 4.4 4 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 JIP_LZII PF16471.5 CDJ59869.1 - 0.092 12.9 17.2 8.5 6.6 0.1 5.0 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II FAP206 PF12018.8 CDJ59869.1 - 0.097 12.2 3.7 3.3 7.1 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function CASP_C PF08172.12 CDJ59869.1 - 0.13 11.6 15.4 1.6 8.0 0.9 2.9 2 1 0 2 2 2 0 CASP C terminal SlyX PF04102.12 CDJ59869.1 - 0.15 12.7 16.0 20 5.9 1.9 4.9 4 1 0 4 4 4 0 SlyX Borrelia_REV PF03978.13 CDJ59869.1 - 0.35 10.8 4.4 3.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein STAT_alpha PF01017.20 CDJ59869.1 - 0.46 10.4 6.0 2.1 8.2 0.8 2.6 2 0 0 2 2 2 0 STAT protein, all-alpha domain Phage_GP20 PF06810.11 CDJ59869.1 - 0.48 10.2 20.7 7.9 6.3 2.7 4.1 3 1 1 4 4 4 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.8 CDJ59869.1 - 0.56 10.4 22.5 1.3 9.3 4.2 4.0 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 CDJ59869.1 - 0.59 8.7 12.1 0.93 8.0 2.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DivIVA PF05103.13 CDJ59869.1 - 0.64 10.1 19.1 4.9 7.2 0.0 4.9 4 2 0 4 4 4 0 DivIVA protein ZapB PF06005.12 CDJ59869.1 - 0.81 10.2 27.0 11 6.6 7.8 4.5 3 1 0 3 3 3 0 Cell division protein ZapB CCDC-167 PF15188.6 CDJ59869.1 - 0.85 10.0 17.8 4.9 7.6 2.9 4.2 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 Syntaxin PF00804.25 CDJ59869.1 - 1.1 8.9 10.2 0.17 11.5 0.4 2.9 1 1 1 3 3 3 0 Syntaxin PCRF PF03462.18 CDJ59869.1 - 1.1 9.1 12.8 1.7 8.5 3.4 2.4 2 0 0 2 2 2 0 PCRF domain NPV_P10 PF05531.12 CDJ59869.1 - 1.2 9.6 9.9 11 6.6 1.2 3.5 3 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.17 CDJ59869.1 - 2.2 8.2 13.1 7.1 6.6 2.3 3.9 4 0 0 4 4 4 0 Prefoldin subunit DUF4778 PF16008.5 CDJ59869.1 - 2.2 8.3 6.1 3.3 7.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) LOH1CR12 PF10158.9 CDJ59869.1 - 3.1 7.8 6.3 4 7.5 0.5 2.6 3 0 0 3 3 2 0 Tumour suppressor protein DUF1515 PF07439.11 CDJ59869.1 - 3.5 7.7 8.9 12 5.9 2.3 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1515) Uds1 PF15456.6 CDJ59869.1 - 3.5 7.8 22.4 3.2 7.9 8.0 3.6 1 1 1 3 3 3 0 Up-regulated During Septation Rho_Binding PF08912.11 CDJ59869.1 - 4.4 8.2 19.1 24 5.9 0.0 4.7 4 2 0 4 4 4 0 Rho Binding SOGA PF11365.8 CDJ59869.1 - 4.5 8.5 15.2 5.3 8.2 2.3 3.6 2 1 2 4 4 4 0 Protein SOGA CK2S PF15011.6 CDJ59869.1 - 4.7 7.1 7.1 2.1 8.2 0.6 2.6 3 0 0 3 3 2 0 Casein Kinase 2 substrate KASH_CCD PF14662.6 CDJ59869.1 - 6.3 6.6 27.2 25 4.6 2.7 3.9 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4618 PF15397.6 CDJ59869.1 - 6.8 6.0 12.9 18 4.6 0.7 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) GIT_CC PF16559.5 CDJ59869.1 - 7.1 6.6 8.4 40 4.2 1.9 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 CDJ59869.1 - 8.9 6.4 18.2 7 6.7 4.4 3.6 2 2 0 3 3 3 0 FlxA-like protein NYD-SP28_assoc PF14775.6 CDJ59869.1 - 9.9 6.4 20.4 5.6 7.1 5.9 4.3 5 1 0 5 5 3 0 Sperm tail C-terminal domain Fmp27_WPPW PF10359.9 CDJ59869.1 - 10 4.9 8.1 1.7 7.4 1.9 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ArfGap PF01412.18 CDJ59870.1 - 1.7e-27 95.8 0.0 3.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Sec23_trunk PF04811.15 CDJ59871.1 - 9.6e-21 74.5 0.8 3.4e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CDJ59871.1 - 9.9e-10 38.3 4.2 2.2e-09 37.2 4.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CDJ59871.1 - 2.3e-05 25.0 0.0 0.0003 21.5 0.0 2.9 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Peptidase_M18 PF02127.15 CDJ59872.1 - 1.2e-109 367.0 0.0 2e-75 254.2 0.0 2.0 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CDJ59872.1 - 8.6e-08 31.5 0.0 8.4e-05 21.7 0.0 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Actin PF00022.19 CDJ59873.1 - 1e-23 83.6 0.0 1.3e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 Actin PPR_2 PF13041.6 CDJ59875.1 - 2.8e-49 165.1 2.7 3.2e-15 56.0 0.0 6.3 2 1 4 6 6 6 6 PPR repeat family PPR PF01535.20 CDJ59875.1 - 6.9e-36 120.0 4.9 5.5e-06 26.3 0.0 8.0 7 1 1 8 8 8 6 PPR repeat PPR_3 PF13812.6 CDJ59875.1 - 1e-34 118.4 0.0 7e-14 51.7 0.0 4.3 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 CDJ59875.1 - 3.3e-30 103.5 0.5 2e-08 33.8 0.0 6.6 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 CDJ59875.1 - 7.5e-21 74.5 0.1 1.2e-13 50.9 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CDJ59875.1 - 0.0042 16.9 0.0 4.4 7.2 0.0 3.1 2 1 0 3 3 3 2 Mitochondrial ATPase expression 2TM PF13239.6 CDJ59877.1 - 0.71 10.2 0.1 0.71 10.2 0.1 3.8 2 1 1 3 3 3 0 2TM domain Metallophos PF00149.28 CDJ59878.1 - 6.1e-05 23.6 0.0 0.0027 18.2 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ59878.1 - 0.0012 19.1 0.0 1.8 8.8 0.0 2.9 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain PUB PF09409.10 CDJ59879.1 - 5.9e-20 71.0 0.0 1.9e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 CDJ59879.1 - 0.0077 16.1 0.1 0.023 14.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain MAJIN PF15077.6 CDJ59879.1 - 0.0081 16.0 7.5 0.012 15.4 7.5 1.2 1 0 0 1 1 1 1 Membrane-anchored junction protein Exonuc_VII_L PF02601.15 CDJ59879.1 - 0.44 10.1 7.1 0.53 9.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5401 PF17380.2 CDJ59879.1 - 0.73 7.8 21.6 1.1 7.3 21.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) 3HCDH_N PF02737.18 CDJ59879.1 - 1.1 9.1 5.5 2.2 8.1 5.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain V_ATPase_I PF01496.19 CDJ59879.1 - 2.8 5.7 6.5 3.2 5.6 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Selenoprotein_S PF06936.11 CDJ59879.1 - 3.7 7.3 14.9 6.8 6.5 14.9 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) APG6_N PF17675.1 CDJ59881.1 - 9e-10 39.2 7.7 9e-10 39.2 7.7 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region DASH_Dad3 PF08656.10 CDJ59881.1 - 0.12 12.5 1.8 0.25 11.5 1.8 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 AAA_13 PF13166.6 CDJ59881.1 - 0.27 9.8 3.4 0.39 9.3 3.4 1.1 1 0 0 1 1 1 0 AAA domain TEX13 PF15186.6 CDJ59881.1 - 2.1 8.0 8.7 3.6 7.3 8.7 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family APG6 PF04111.12 CDJ59882.1 - 8.9e-25 87.7 0.0 1e-24 87.5 0.0 1.0 1 0 0 1 1 1 1 Apg6 BARA domain Integrase_H2C2 PF17921.1 CDJ59883.1 - 2.8e-17 62.6 0.4 2.8e-17 62.6 0.4 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 CDJ59883.1 - 4.6e-17 62.3 0.0 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDJ59883.1 - 3.9e-11 42.7 0.0 8.3e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CDJ59883.1 - 3.9e-09 36.4 0.0 8.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDJ59883.1 - 0.0052 17.0 0.1 0.015 15.5 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDJ59883.1 - 0.0091 15.8 1.9 0.017 14.9 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CDJ59883.1 - 0.023 15.0 0.1 0.072 13.4 0.1 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase TFIIA PF03153.13 CDJ59883.1 - 7.9 6.4 54.3 1.8 8.4 46.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FoP_duplication PF13865.6 CDJ59884.1 - 0.28 11.8 3.2 0.39 11.3 0.5 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 UQ_con PF00179.26 CDJ59885.1 - 5.5e-07 29.3 0.0 9.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.27 CDJ59886.1 - 6.3e-15 54.9 8.4 3.2e-08 33.4 0.0 3.4 3 1 1 4 4 4 3 Mitochondrial carrier protein DUF2399 PF09664.10 CDJ59886.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Spt20 PF12090.8 CDJ59886.1 - 0.017 14.7 7.5 0.021 14.5 7.5 1.1 1 0 0 1 1 1 0 Spt20 family Hormone_1 PF00103.20 CDJ59886.1 - 0.057 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Somatotropin hormone family AMMECR1 PF01871.17 CDJ59886.1 - 0.068 12.8 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 AMMECR1 CYSTM PF12734.7 CDJ59886.1 - 0.13 12.6 7.8 0.3 11.4 7.8 1.6 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2722 PF10846.8 CDJ59886.1 - 0.26 10.2 6.2 0.32 9.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 CDJ59886.1 - 0.96 8.6 9.3 1.3 8.2 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RskA PF10099.9 CDJ59887.1 - 0.0012 19.2 5.9 0.0012 19.2 5.9 4.2 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Peptidase_S8 PF00082.22 CDJ59888.1 - 1.6e-06 27.6 7.7 1.6e-06 27.6 7.7 4.7 3 2 0 3 3 3 1 Subtilase family Collagen PF01391.18 CDJ59888.1 - 0.18 11.6 5.5 0.43 10.4 5.5 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) EOS1 PF12326.8 CDJ59888.1 - 0.89 9.5 2.8 24 4.8 1.3 2.4 2 0 0 2 2 2 0 N-glycosylation protein DUF4667 PF15700.5 CDJ59888.1 - 0.98 9.5 8.3 2.8 8.0 8.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF572 PF04502.13 CDJ59888.1 - 1.1 8.8 19.9 3.3 7.2 2.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2813 PF11398.8 CDJ59888.1 - 1.3 8.2 15.8 2.6 7.2 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) FAM60A PF15396.6 CDJ59888.1 - 3.9 7.4 13.8 5.9 6.8 6.7 2.4 2 0 0 2 2 2 0 Protein Family FAM60A MPM1 PF17234.2 CDJ59888.1 - 5.1 7.3 18.8 2 8.6 2.5 2.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF2722 PF10846.8 CDJ59888.1 - 5.7 5.8 36.7 0.27 10.1 9.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MMR1 PF08505.10 CDJ59888.1 - 9.7 6.4 24.1 4.2 7.6 12.6 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein zf-RING_2 PF13639.6 CDJ59889.1 - 3.9e-12 46.3 10.9 5.7e-12 45.8 10.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDJ59889.1 - 5.1e-07 29.9 10.2 7.8e-07 29.3 9.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDJ59889.1 - 1e-06 28.5 7.7 1.5e-06 28.0 7.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ59889.1 - 3.3e-06 27.1 4.3 4.9e-06 26.5 4.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDJ59889.1 - 8.7e-06 25.8 4.5 1.6e-05 24.9 4.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.6 CDJ59889.1 - 1.7e-05 24.7 6.4 2.9e-05 23.9 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDJ59889.1 - 2.4e-05 24.1 10.6 3.9e-05 23.4 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ59889.1 - 3.1e-05 23.6 2.6 3.1e-05 23.6 2.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ59889.1 - 0.00021 21.2 1.0 0.00021 21.2 1.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CDJ59889.1 - 0.0011 18.7 4.9 0.0017 18.1 4.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF5318 PF17249.2 CDJ59889.1 - 0.0024 17.7 1.2 0.0066 16.2 1.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5318) zf-C3HC4 PF00097.25 CDJ59889.1 - 0.0027 17.6 8.9 0.0049 16.7 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ59889.1 - 0.0031 17.3 10.3 0.014 15.3 7.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDJ59889.1 - 0.0089 16.2 6.2 0.058 13.6 6.0 2.2 1 1 1 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 CDJ59889.1 - 0.011 15.6 6.2 0.12 12.4 3.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 CDJ59889.1 - 0.024 14.2 6.0 0.04 13.5 6.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 CDJ59889.1 - 0.059 13.0 0.5 0.059 13.0 0.5 2.2 1 1 1 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.14 CDJ59889.1 - 0.29 11.0 1.3 3.7 7.5 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif Baculo_RING PF05883.11 CDJ59889.1 - 0.36 10.8 1.7 0.61 10.1 1.7 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_2 PF13923.6 CDJ59890.1 - 1e-09 38.1 7.5 3e-09 36.6 7.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ59890.1 - 7.7e-08 32.1 3.6 2.1e-07 30.7 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDJ59890.1 - 2.8e-07 30.3 5.4 8e-07 28.8 5.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ59890.1 - 7.1e-07 29.5 6.7 2.2e-06 27.9 6.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDJ59890.1 - 9.4e-06 25.5 4.9 3e-05 23.9 4.9 2.0 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ59890.1 - 1.6e-05 24.7 5.0 3.8e-05 23.5 5.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDJ59890.1 - 1.6e-05 24.9 8.6 1.6e-05 24.9 8.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 CDJ59890.1 - 0.00011 22.0 2.1 0.00025 20.8 2.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDJ59890.1 - 0.0038 17.4 10.7 0.0038 17.4 10.7 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Peptidase_C97 PF05903.14 CDJ59890.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-rbx1 PF12678.7 CDJ59890.1 - 1.1 9.6 9.9 0.17 12.2 3.9 2.9 3 0 0 3 3 2 0 RING-H2 zinc finger domain MACPF PF01823.19 CDJ59894.1 - 0.011 15.8 2.1 0.015 15.4 2.1 1.3 1 0 0 1 1 1 0 MAC/Perforin domain Vps23_core PF09454.10 CDJ59894.1 - 0.018 15.0 0.8 0.074 13.0 0.1 2.3 2 1 1 3 3 3 0 Vps23 core domain DUF1732 PF08340.11 CDJ59894.1 - 0.085 12.8 2.0 0.13 12.3 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) KIAA1430 PF13879.6 CDJ59894.1 - 0.22 12.3 8.7 0.33 11.7 8.7 1.4 1 1 0 1 1 1 0 KIAA1430 homologue BLOC1_2 PF10046.9 CDJ59894.1 - 0.37 11.1 5.6 2.3 8.6 1.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.9 CDJ59895.1 - 0.00011 21.9 20.2 0.0011 18.6 11.6 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ59895.1 - 0.0014 17.7 5.3 0.0014 17.7 5.3 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) E_Pc_C PF06752.12 CDJ59895.1 - 0.0025 18.0 12.5 0.0025 18.0 12.5 2.6 2 1 0 2 2 1 1 Enhancer of Polycomb C-terminus Spt20 PF12090.8 CDJ59895.1 - 0.008 15.8 10.7 0.008 15.8 10.7 2.5 3 0 0 3 3 3 2 Spt20 family RskA PF10099.9 CDJ59895.1 - 0.018 15.4 13.1 0.018 15.4 13.1 3.1 1 1 2 3 3 2 0 Anti-sigma-K factor rskA Sigma70_ECF PF07638.11 CDJ59895.1 - 0.018 14.9 0.1 0.018 14.9 0.1 1.6 2 0 0 2 2 2 0 ECF sigma factor RseA_C PF03873.13 CDJ59895.1 - 0.078 13.2 23.1 1.3 9.4 3.8 2.8 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain RAB3GAP2_N PF14655.6 CDJ59895.1 - 0.45 9.7 7.3 0.1 11.9 1.3 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_S64 PF08192.11 CDJ59895.1 - 0.62 8.5 20.5 0.38 9.2 11.2 2.0 2 0 0 2 2 2 0 Peptidase family S64 DUF3439 PF11921.8 CDJ59895.1 - 2.3 8.2 7.2 8.9 6.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Maf1 PF09174.10 CDJ59895.1 - 3.6 7.7 10.6 7.8 6.6 1.3 2.3 2 0 0 2 2 2 0 Maf1 regulator Activator_LAG-3 PF11498.8 CDJ59895.1 - 4.6 6.1 33.2 0.022 13.8 0.9 2.6 3 0 0 3 3 3 0 Transcriptional activator LAG-3 DUF1635 PF07795.11 CDJ59895.1 - 5.2 6.9 21.4 0.21 11.4 7.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF755 PF05501.11 CDJ59895.1 - 7.7 6.8 37.2 0.73 10.1 20.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SART-1 PF03343.13 CDJ59896.1 - 3e-52 178.1 78.1 9e-32 110.4 72.3 4.2 1 1 1 2 2 2 2 SART-1 family MPP6 PF10175.9 CDJ59897.1 - 3.6e-07 30.8 0.3 4.6e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Spt20 PF12090.8 CDJ59897.1 - 0.027 14.1 5.3 0.03 13.9 5.3 1.1 1 0 0 1 1 1 0 Spt20 family DUF1411 PF07199.11 CDJ59897.1 - 0.034 13.8 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) K_channel_TID PF07941.11 CDJ59897.1 - 0.11 13.0 12.8 0.056 13.9 6.0 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FTZ PF03867.14 CDJ59897.1 - 0.18 11.3 5.6 0.33 10.5 5.7 1.3 1 1 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TFIIA PF03153.13 CDJ59897.1 - 0.26 11.2 9.1 0.31 11.0 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 CDJ59898.1 - 4.6e-37 127.7 25.8 1.9e-20 73.1 0.2 4.1 2 1 2 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ59898.1 - 7.4e-11 42.2 5.0 7.4e-11 42.2 5.0 4.0 3 1 0 3 3 3 1 Microtubule binding Androgen_recep PF02166.16 CDJ59898.1 - 0.0032 16.4 7.1 0.0032 16.4 7.1 9.7 6 3 4 10 10 10 1 Androgen receptor Spt20 PF12090.8 CDJ59898.1 - 0.0044 16.7 13.7 0.0044 16.7 13.7 7.9 6 2 1 7 7 7 3 Spt20 family RskA PF10099.9 CDJ59898.1 - 0.36 11.1 0.1 0.36 11.1 0.1 6.2 2 2 3 6 6 6 0 Anti-sigma-K factor rskA Hat1_N PF10394.9 CDJ59899.1 - 0.012 15.9 0.1 0.036 14.3 0.1 1.9 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus ANAPC_CDC26 PF10471.9 CDJ59899.1 - 0.035 14.9 4.7 0.035 14.9 4.7 6.7 5 3 1 6 6 6 0 Anaphase-promoting complex APC subunit CDC26 OATP PF03137.20 CDJ59899.1 - 0.17 10.2 5.2 1.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4199 PF13858.6 CDJ59899.1 - 1 9.7 4.8 3.7 7.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) RNA_pol_Rbc25 PF08292.12 CDJ59899.1 - 2.7 8.3 7.6 7.2 6.9 1.0 3.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 DUF4770 PF15994.5 CDJ59899.1 - 3.4 7.9 13.9 9.7 6.4 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) V_ATPase_I PF01496.19 CDJ59899.1 - 4.9 4.9 9.2 7.1 4.4 4.3 2.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Afi1 PF07792.12 CDJ59899.1 - 9.7 6.7 12.3 9 6.8 2.0 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SlyX PF04102.12 CDJ59901.1 - 0.058 14.0 0.9 0.13 12.9 0.3 1.9 2 0 0 2 2 2 0 SlyX ComC PF03047.14 CDJ59901.1 - 0.096 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 COMC family SET PF00856.28 CDJ59902.1 - 4.5e-15 56.4 0.0 6.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 SET domain Serglycin PF04360.12 CDJ59902.1 - 0.055 13.4 9.8 0.091 12.7 9.8 1.3 1 0 0 1 1 1 0 Serglycin MRP-S33 PF08293.11 CDJ59903.1 - 0.079 13.2 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 CFAP91 PF14738.6 CDJ59904.1 - 7e-25 87.9 1.5 7e-25 87.9 1.5 2.5 2 1 0 2 2 2 1 Cilia- and flagella-associated protein 91 Spectrin PF00435.21 CDJ59904.1 - 2.3 8.8 12.7 7.2 7.1 0.4 3.0 2 1 0 2 2 2 0 Spectrin repeat Dpy-30 PF05186.13 CDJ59906.1 - 6.1e-12 45.0 0.2 1.3e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 Dpy-30 motif IRK_C PF17655.1 CDJ59907.1 - 5e-07 29.5 0.0 1.1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain MDM10 PF12519.8 CDJ59909.1 - 0.21 10.4 14.4 0.034 13.0 5.6 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 HAUS6_N PF14661.6 CDJ59909.1 - 0.97 9.0 24.3 0.44 10.1 7.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus XRN_M PF17846.1 CDJ59909.1 - 1.8 7.4 11.1 0.15 10.9 2.4 2.2 2 0 0 2 2 2 0 Xrn1 helical domain Cellulose_synt PF03552.14 CDJ59910.1 - 3.7 5.9 7.7 7.3 4.9 7.7 1.4 1 0 0 1 1 1 0 Cellulose synthase Vps54 PF07928.12 CDJ59911.1 - 9.7e-19 68.1 2.2 9.7e-19 68.1 2.2 5.1 5 0 0 5 5 5 1 Vps54-like protein Caldesmon PF02029.15 CDJ59911.1 - 0.00091 18.1 29.3 0.00091 18.1 29.3 4.7 4 1 0 4 4 4 1 Caldesmon TFIIA PF03153.13 CDJ59911.1 - 0.0015 18.6 19.9 0.0015 18.6 19.9 7.9 4 1 1 6 6 6 4 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ59911.1 - 0.017 15.1 0.3 0.017 15.1 0.3 16.3 11 4 4 15 15 15 0 Unstructured region C-term to UIM in Ataxin3 RtxA PF07634.11 CDJ59911.1 - 1.3 9.7 4.7 0.84 10.3 0.5 3.2 2 0 0 2 2 2 0 RtxA repeat DUF2722 PF10846.8 CDJ59913.1 - 0.013 14.5 0.8 0.013 14.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ59913.1 - 0.019 15.0 17.9 0.52 10.4 0.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 CDJ59913.1 - 0.099 13.6 6.5 0.78 10.7 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 CDJ59913.1 - 0.36 10.9 3.2 2 8.5 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spt20 PF12090.8 CDJ59913.1 - 0.42 10.2 25.4 0.56 9.8 10.6 2.1 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 CDJ59913.1 - 0.62 8.8 5.9 1.1 8.0 5.9 1.4 1 1 0 1 1 1 0 Presenilin TAF4 PF05236.14 CDJ59913.1 - 0.87 9.3 11.6 4.9 6.8 5.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Rad60-SLD_2 PF13881.6 CDJ59913.1 - 2.2 8.4 6.7 2.8 8.1 1.6 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DRY_EERY PF09750.9 CDJ59913.1 - 4.2 7.7 10.0 2 8.7 1.0 2.1 2 0 0 2 2 2 0 Alternative splicing regulator SR-25 PF10500.9 CDJ59914.1 - 0.0013 18.4 14.7 0.0013 18.4 14.7 2.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ59914.1 - 0.076 12.0 11.8 1.1 8.2 0.5 2.1 2 0 0 2 2 2 0 Solute carrier family 12 DUF406 PF04175.12 CDJ59914.1 - 0.076 13.5 0.6 0.076 13.5 0.6 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF406) DUF2149 PF09919.9 CDJ59914.1 - 0.092 13.0 0.5 0.092 13.0 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) MRPL52 PF18699.1 CDJ59914.1 - 0.22 11.7 12.5 0.06 13.5 1.1 2.4 2 0 0 2 2 2 0 Mitoribosomal protein mL52 DUF4834 PF16118.5 CDJ59914.1 - 0.24 12.4 0.2 0.24 12.4 0.2 3.4 2 1 1 3 3 1 0 Domain of unknown function (DUF4834) Macoilin PF09726.9 CDJ59914.1 - 0.34 9.4 14.2 0.31 9.5 7.0 2.2 2 0 0 2 2 2 0 Macoilin family Folliculin PF11704.8 CDJ59914.1 - 2.5 8.0 12.5 0.23 11.3 0.5 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport SPX PF03105.19 CDJ59914.1 - 4.8 7.0 25.5 2.7 7.8 12.7 2.2 2 0 0 2 2 2 0 SPX domain FAM60A PF15396.6 CDJ59914.1 - 5 7.1 12.0 10 6.0 8.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF1644 PF07800.12 CDJ59914.1 - 7.7 6.5 10.2 0.59 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Fumerase_C PF05683.12 CDJ59916.1 - 3.9e-68 228.8 0.1 2.7e-67 226.1 0.0 1.8 1 1 1 2 2 2 1 Fumarase C-terminus Fumerase PF05681.14 CDJ59916.1 - 2.6e-07 30.4 0.0 3.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) GTP-bdg_M PF16360.5 CDJ59917.1 - 0.53 10.9 5.1 3.1 8.5 5.0 2.5 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Podoplanin PF05808.11 CDJ59918.1 - 4.1 7.5 9.5 0.077 13.1 1.7 2.1 2 0 0 2 2 2 0 Podoplanin PDDEXK_10 PF07788.11 CDJ59919.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Adaptin_binding PF10199.9 CDJ59919.1 - 9 6.9 6.4 46 4.6 3.4 3.1 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RNA_pol_Rpb4 PF03874.16 CDJ59920.1 - 1.4 9.3 4.0 1.3 9.4 0.2 2.7 3 1 1 4 4 4 0 RNA polymerase Rpb4 DUF948 PF06103.11 CDJ59921.1 - 0.42 10.9 5.2 0.53 10.6 0.1 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) 7TMR-HDED PF07697.11 CDJ59921.1 - 3.9 7.5 10.3 0.13 12.4 1.8 2.4 2 1 0 2 2 2 0 7TM-HD extracellular Helicase_C_2 PF13307.6 CDJ59922.1 - 1.6e-36 126.0 1.8 1.2e-33 116.7 0.1 3.3 3 0 0 3 3 3 2 Helicase C-terminal domain DEAD_2 PF06733.15 CDJ59922.1 - 6.2e-28 97.6 0.0 2.4e-27 95.7 0.0 2.1 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CDJ59922.1 - 0.0077 16.0 0.2 0.035 13.9 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3015 PF11220.8 CDJ59922.1 - 0.03 14.2 0.8 1.2 9.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) AAT PF03417.16 CDJ59922.1 - 0.032 13.9 6.1 1 9.0 0.4 2.7 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DNA_pol_D_N PF18018.1 CDJ59924.1 - 0.012 15.8 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain THOC2_N PF16134.5 CDJ59924.1 - 0.51 8.9 6.4 0.62 8.6 6.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Pkinase PF00069.25 CDJ59925.1 - 9.9e-10 38.2 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59925.1 - 3.1e-05 23.4 0.0 3.2e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ59925.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ59925.1 - 0.055 13.4 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M24 PF00557.24 CDJ59926.1 - 5.6e-30 104.6 0.0 8.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Aa_trans PF01490.18 CDJ59927.1 - 0.073 11.8 21.9 0.27 9.9 2.8 2.5 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein WW PF00397.26 CDJ59929.1 - 4.3e-07 29.9 2.6 1e-06 28.7 2.6 1.7 1 0 0 1 1 1 1 WW domain DegT_DnrJ_EryC1 PF01041.17 CDJ59931.1 - 1.7e-17 63.8 0.0 6.7e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family AAA_9 PF12781.7 CDJ59932.1 - 1.7e-54 184.3 0.6 1.5e-52 177.9 0.0 2.8 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDJ59932.1 - 4.3e-39 134.6 1.2 8.7e-37 127.0 0.3 2.3 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ59932.1 - 4.5e-37 126.8 0.1 2.3e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDJ59932.1 - 3.7e-36 124.9 6.4 3.7e-36 124.9 6.4 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 CDJ59932.1 - 3e-32 112.0 0.0 2.3e-18 66.5 0.0 3.4 1 1 1 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ59932.1 - 1.7e-27 96.1 0.0 3.3e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDJ59932.1 - 1.9e-15 57.1 0.0 5.7e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ59932.1 - 1.3e-07 31.7 0.0 4.4e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain DHR10 PF18595.1 CDJ59932.1 - 0.0017 18.4 5.0 0.0017 18.4 5.0 2.6 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain AcylCoA_dehyd_C PF12186.8 CDJ59932.1 - 0.088 12.9 2.3 1.4 9.1 0.3 3.0 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal Sec8_exocyst PF04048.14 CDJ59932.1 - 1.1 9.2 5.4 1.1 9.1 0.8 3.2 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain UPF0242 PF06785.11 CDJ59932.1 - 1.9 8.5 6.2 0.57 10.3 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CDJ59932.1 - 2.9 6.7 15.8 0.05 12.5 3.8 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 CDJ59932.1 - 4.1 7.1 16.8 0.082 12.6 4.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DHC_N2 PF08393.13 CDJ59933.1 - 3.4e-96 322.8 1.3 3.4e-96 322.8 1.3 2.4 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CDJ59933.1 - 7.7e-86 288.0 0.0 8.7e-63 212.3 0.0 2.4 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CDJ59933.1 - 1.7e-14 54.0 0.2 0.0012 18.8 0.0 5.0 3 2 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ59933.1 - 4e-11 43.6 0.1 0.00041 20.9 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CDJ59933.1 - 1.6e-06 28.5 0.5 0.0026 18.2 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDJ59933.1 - 4.2e-05 23.9 0.4 0.49 10.6 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CDJ59933.1 - 4.2e-05 23.8 0.1 0.096 13.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ59933.1 - 0.00015 22.2 3.2 0.093 13.1 0.0 3.7 4 1 0 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 CDJ59933.1 - 0.00017 21.8 0.0 0.28 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDJ59933.1 - 0.00063 19.5 0.6 0.78 9.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDJ59933.1 - 0.00083 18.9 0.1 0.46 10.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CDJ59933.1 - 0.0022 18.0 0.4 1.7 8.5 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain ABC_tran PF00005.27 CDJ59933.1 - 0.0042 17.6 0.1 0.034 14.7 0.0 2.6 3 0 0 3 3 1 1 ABC transporter RNA_helicase PF00910.22 CDJ59933.1 - 0.0044 17.4 0.0 2 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 CDJ59933.1 - 0.0094 16.0 0.1 0.028 14.5 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CDJ59933.1 - 0.017 15.0 0.1 0.054 13.4 0.0 1.8 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 CDJ59933.1 - 0.021 14.8 0.5 1.9 8.4 0.1 3.4 3 0 0 3 3 2 0 NACHT domain Viral_helicase1 PF01443.18 CDJ59933.1 - 0.026 14.3 0.2 0.43 10.3 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 CDJ59933.1 - 0.028 14.2 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 CDJ59933.1 - 0.028 14.7 2.4 2.8 8.3 0.1 3.6 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 CDJ59933.1 - 0.037 13.3 0.6 0.27 10.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 CDJ59933.1 - 0.038 13.4 1.3 0.1 12.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CDJ59933.1 - 0.04 13.8 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 CDJ59933.1 - 0.044 13.8 0.2 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CDJ59933.1 - 0.045 13.0 0.1 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_17 PF13207.6 CDJ59933.1 - 0.098 13.1 0.2 35 4.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF4200 PF13863.6 CDJ59933.1 - 0.13 12.7 8.0 0.082 13.3 4.7 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.6 CDJ59933.1 - 0.16 11.6 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CDJ59933.1 - 0.17 11.6 5.9 2.1 8.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CDJ59933.1 - 0.45 10.1 2.5 0.89 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain DegQ PF08181.11 CDJ59933.1 - 1 9.5 4.2 0.79 9.9 0.2 3.0 3 0 0 3 3 2 0 DegQ (SacQ) family ATP_bind_1 PF03029.17 CDJ59933.1 - 2.2 8.0 4.2 3.8 7.2 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Peptidase_A17 PF05380.13 CDJ59934.1 - 0.4 10.7 6.8 1.1 9.3 1.9 2.5 1 1 1 2 2 2 0 Pao retrotransposon peptidase Exonuc_VII_L PF02601.15 CDJ59934.1 - 0.46 10.0 6.8 0.61 9.6 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MeaB PF03308.16 CDJ59934.1 - 0.68 8.9 4.8 0.94 8.4 4.8 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2362 PF10154.9 CDJ59934.1 - 1.7 7.5 12.5 2.3 7.1 12.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF883 PF05957.13 CDJ59934.1 - 1.7 9.3 7.4 8.2 7.1 0.9 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Retrotrans_gag PF03732.17 CDJ59934.1 - 3.3 8.1 12.3 9.4 6.6 11.6 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein Pkinase PF00069.25 CDJ59935.1 - 3.3e-13 49.6 0.0 4.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59935.1 - 3.1e-05 23.4 0.0 3.8e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ59935.1 - 0.00014 20.7 0.0 0.00017 20.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ59935.1 - 0.0065 16.4 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ59935.1 - 0.07 12.7 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CDJ59935.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAGE_N PF12440.8 CDJ59935.1 - 0.71 10.6 4.1 0.96 10.2 4.1 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SUIM_assoc PF16619.5 CDJ59939.1 - 7.1e-05 22.8 0.4 7.1e-05 22.8 0.4 4.1 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 CDJ59939.1 - 0.0011 19.3 13.1 0.0011 19.3 13.1 6.1 1 1 3 4 4 4 1 Anti-sigma-K factor rskA CLN3 PF02487.17 CDJ59939.1 - 0.34 9.9 2.3 0.71 8.8 2.3 1.7 1 0 0 1 1 1 0 CLN3 protein Mog1 PF04603.12 CDJ59941.1 - 2.1e-24 86.5 0.0 2e-23 83.3 0.0 1.9 1 1 0 1 1 1 1 Ran-interacting Mog1 protein ANAPC15 PF15243.6 CDJ59942.1 - 0.0013 19.1 4.4 0.0016 18.8 4.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Adenylsucc_synt PF00709.21 CDJ59942.1 - 0.027 13.4 0.1 0.03 13.2 0.1 1.0 1 0 0 1 1 1 0 Adenylosuccinate synthetase PP_kinase_C_1 PF17941.1 CDJ59942.1 - 0.057 13.0 0.6 0.074 12.6 0.6 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 NOA36 PF06524.12 CDJ59942.1 - 1.2 8.4 5.3 1.3 8.3 5.3 1.0 1 0 0 1 1 1 0 NOA36 protein ubiquitin PF00240.23 CDJ59943.1 - 1e-09 38.0 0.1 3.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_4 PF18036.1 CDJ59943.1 - 0.00031 20.7 0.1 0.041 13.9 0.1 2.9 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ59943.1 - 0.0041 16.9 0.2 0.0091 15.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 CDJ59943.1 - 0.059 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 IMCp PF12314.8 CDJ59944.1 - 2.3e-24 85.5 51.6 2.8e-24 85.2 17.8 3.8 2 1 2 4 4 4 3 Inner membrane complex protein VPS11_C PF12451.8 CDJ59945.1 - 9e-05 22.6 0.1 0.0002 21.5 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal AsnA PF03590.15 CDJ59946.1 - 8.8e-52 176.1 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 CDJ59946.1 - 0.054 12.6 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Ribosomal_L24e PF01246.20 CDJ59947.1 - 7.8e-24 83.7 0.6 7.8e-24 83.7 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CDJ59947.1 - 0.021 14.3 0.5 0.026 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) EF-hand_7 PF13499.6 CDJ59948.1 - 1.8e-15 57.1 3.7 2e-15 57.0 3.7 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ59948.1 - 5.4e-15 55.0 1.5 5.4e-15 55.0 1.5 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ59948.1 - 2.8e-14 51.5 5.8 4.3e-09 35.3 2.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ59948.1 - 1.1e-12 46.8 3.2 2.2e-05 24.0 0.5 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ59948.1 - 6.4e-08 31.8 6.9 3.5e-06 26.3 1.3 2.7 2 1 1 3 3 3 2 EF hand EF-hand_9 PF14658.6 CDJ59948.1 - 1.2e-07 31.9 0.1 1.4e-07 31.7 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 CDJ59948.1 - 0.00094 19.1 0.3 0.0011 18.9 0.3 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 CDJ59948.1 - 0.02 15.2 0.3 0.052 13.9 0.3 1.6 1 1 0 1 1 1 0 EF-hand domain Mst1_SARAH PF11629.8 CDJ59948.1 - 0.039 14.0 1.5 0.068 13.3 1.2 1.6 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 PhetRS_B1 PF18262.1 CDJ59948.1 - 0.065 13.5 0.2 0.071 13.3 0.2 1.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain DUF3008 PF11450.8 CDJ59948.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) PB1 PF00564.24 CDJ59948.1 - 0.12 12.4 1.5 4.8 7.2 0.1 2.5 2 1 1 3 3 3 0 PB1 domain Tsc35 PF15079.6 CDJ59948.1 - 0.13 11.8 1.1 0.15 11.6 1.1 1.0 1 0 0 1 1 1 0 Testis-specific protein 35 PI3K_1B_p101 PF10486.9 CDJ59949.1 - 4.3 5.0 19.5 5 4.8 19.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BTB PF00651.31 CDJ59950.1 - 2.2e-11 44.0 0.0 1.8e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain UPF0565 PF10561.9 CDJ59950.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 SIR2 PF02146.17 CDJ59951.1 - 8.7e-34 117.0 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDJ59951.1 - 0.00085 19.1 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain EFG_II PF14492.6 CDJ59952.1 - 1.9e-06 27.8 0.1 4.3e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 CDJ59952.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV Ribosomal_S19 PF00203.21 CDJ59954.1 - 2.4e-30 104.2 0.1 3.2e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 CS PF04969.16 CDJ59955.1 - 2.9e-10 41.0 0.0 4.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.11 CDJ59955.1 - 2e-06 28.0 0.1 6.5e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Siah interacting protein, N terminal SGS PF05002.15 CDJ59955.1 - 1.2e-05 25.3 1.0 0.00018 21.5 1.3 2.1 2 0 0 2 2 2 1 SGS domain Ribosomal_S3Ae PF01015.18 CDJ59956.1 - 2.8e-89 298.0 0.1 3.5e-89 297.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CDJ59956.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Kelch_3 PF13415.6 CDJ59957.1 - 1.2e-16 60.5 3.2 5.2e-07 29.8 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ59957.1 - 3.2e-16 58.9 0.6 0.0038 17.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CDJ59957.1 - 3.9e-14 52.4 4.9 1.3e-05 25.1 0.0 5.7 4 1 1 5 5 5 3 Galactose oxidase, central domain HATPase_c_3 PF13589.6 CDJ59957.1 - 1.5e-09 37.8 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.25 CDJ59957.1 - 7.2e-05 22.3 0.1 1.9 8.1 0.0 3.8 3 0 0 3 3 3 2 Kelch motif HATPase_c PF02518.26 CDJ59957.1 - 0.00012 22.5 0.0 0.00027 21.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 CDJ59957.1 - 0.0012 19.0 2.5 0.077 13.3 0.1 4.1 2 2 2 5 5 5 1 Kelch motif Zn_ribbon_17 PF17120.5 CDJ59958.1 - 2.5 7.8 6.1 0.4 10.3 1.8 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PDCD2_C PF04194.13 CDJ59959.1 - 1.3e-37 129.5 1.2 2.6e-36 125.3 0.1 2.3 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-RRN7 PF11781.8 CDJ59959.1 - 0.00094 18.8 0.9 0.068 12.9 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Type_ISP_C PF18135.1 CDJ59959.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain zinc_ribbon_2 PF13240.6 CDJ59959.1 - 0.81 9.5 8.6 2.4 8.0 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain vATP-synt_E PF01991.18 CDJ59960.1 - 1.9e-58 197.1 2.1 2.3e-58 196.9 2.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.6 CDJ59960.1 - 0.0068 16.1 4.9 0.073 12.8 5.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4239) IL13 PF03487.13 CDJ59960.1 - 0.056 13.2 1.7 0.11 12.2 0.4 2.0 2 0 0 2 2 2 0 Interleukin-13 Helicase_PWI PF18149.1 CDJ59960.1 - 0.081 13.1 7.0 0.047 13.9 3.0 2.2 2 0 0 2 2 2 0 N-terminal helicase PWI domain CemA PF03040.14 CDJ59960.1 - 0.24 11.3 4.9 0.34 10.8 4.9 1.3 1 0 0 1 1 1 0 CemA family DUF445 PF04286.12 CDJ59960.1 - 1.4 8.7 9.3 1.7 8.4 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Dynein_light PF01221.18 CDJ59960.1 - 5.5 7.4 5.9 4.1 7.8 3.5 2.0 2 0 0 2 2 2 0 Dynein light chain type 1 CutA1 PF03091.15 CDJ59961.1 - 3.3e-31 107.1 1.3 6.9e-15 54.7 0.1 2.0 2 0 0 2 2 2 2 CutA1 divalent ion tolerance protein AsnC_trans_reg PF01037.21 CDJ59961.1 - 0.034 14.1 1.0 0.27 11.2 0.2 2.5 2 1 1 3 3 3 0 Lrp/AsnC ligand binding domain ubiquitin PF00240.23 CDJ59962.1 - 2.8e-70 232.0 3.9 2.5e-34 116.9 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDJ59962.1 - 8.4e-34 115.2 5.0 3.2e-16 58.9 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ59962.1 - 1.1e-13 51.5 0.7 4.3e-05 23.9 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ59962.1 - 1.6e-08 34.3 0.2 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ59962.1 - 1.2e-07 31.8 0.2 0.029 14.5 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDJ59962.1 - 1.3e-07 31.9 0.2 0.02 15.2 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 CDJ59962.1 - 4.6e-06 27.1 0.0 0.15 12.6 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDJ59962.1 - 7.5e-05 22.7 6.6 9.3 6.4 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CDJ59962.1 - 0.00048 20.0 0.0 0.96 9.3 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 CDJ59962.1 - 0.014 15.8 0.1 11 6.4 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2870) TmoB PF06234.12 CDJ59962.1 - 0.059 13.5 0.3 18 5.5 0.0 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FERM_f0 PF16511.5 CDJ59962.1 - 0.066 13.5 1.9 33 4.9 0.2 3.6 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM UDP-g_GGTase PF06427.11 CDJ59962.1 - 0.11 12.6 0.2 2.1 8.5 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase FlgD_ig PF13860.6 CDJ59962.1 - 0.12 12.2 0.6 22 5.0 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain DUF969 PF06149.12 CDJ59962.1 - 0.19 11.1 0.0 6.7 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Pkinase PF00069.25 CDJ59964.1 - 8.1e-13 48.3 2.6 1.1e-07 31.5 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ59964.1 - 0.1 11.9 1.3 1.3 8.3 0.0 3.1 3 1 0 3 3 3 0 Protein tyrosine kinase CTU2 PF10288.9 CDJ59964.1 - 1.1 9.5 13.7 0.094 13.0 0.5 3.5 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF2722 PF10846.8 CDJ59964.1 - 1.3 7.9 49.8 0.014 14.3 0.9 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2722) MPM1 PF17234.2 CDJ59964.1 - 3.5 7.9 14.9 1 9.6 1.7 3.0 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 CDC45 PF02724.14 CDJ59965.1 - 0.0018 16.7 13.3 0.0018 16.7 13.3 2.1 2 0 0 2 2 2 1 CDC45-like protein Apt1 PF10351.9 CDJ59965.1 - 0.0032 16.4 8.4 0.0032 16.4 8.4 2.9 3 0 0 3 3 3 1 Golgi-body localisation protein domain PP2C PF00481.21 CDJ59965.1 - 0.06 13.0 0.0 0.06 13.0 0.0 2.9 3 1 0 3 3 3 0 Protein phosphatase 2C YL1 PF05764.13 CDJ59965.1 - 2.5 8.2 33.5 0.068 13.3 16.0 2.6 2 0 0 2 2 2 0 YL1 nuclear protein CDK2AP PF09806.9 CDJ59966.1 - 0.0062 16.6 3.8 0.0068 16.5 3.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein CIAPIN1 PF05093.13 CDJ59966.1 - 0.0074 16.8 2.3 0.0088 16.5 2.3 1.1 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis WBP-1 PF11669.8 CDJ59966.1 - 0.0084 16.7 1.5 0.0095 16.6 1.5 1.1 1 0 0 1 1 1 1 WW domain-binding protein 1 DivIC PF04977.15 CDJ59966.1 - 0.014 15.1 4.3 0.017 14.9 4.3 1.1 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDJ59966.1 - 0.031 13.9 12.9 0.034 13.8 12.9 1.1 1 0 0 1 1 1 0 Spt20 family TssO PF17561.2 CDJ59966.1 - 0.032 14.3 3.0 0.04 14.0 3.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF1206 PF06724.11 CDJ59966.1 - 0.037 14.1 0.3 0.037 14.1 0.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) UPF0524 PF15823.5 CDJ59966.1 - 0.044 13.2 2.2 0.054 12.9 2.2 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 OPA3 PF07047.12 CDJ59966.1 - 0.048 13.5 0.6 0.062 13.1 0.6 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF1645 PF07816.11 CDJ59966.1 - 0.072 13.7 6.3 0.085 13.4 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Cytochrom_C_asm PF01578.20 CDJ59966.1 - 0.073 12.8 0.2 0.083 12.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein AF-4 PF05110.13 CDJ59966.1 - 0.073 11.2 13.8 0.089 10.9 13.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 CDJ59966.1 - 0.085 12.8 13.3 0.088 12.8 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2227 PF09988.9 CDJ59966.1 - 0.19 11.6 0.2 0.21 11.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) DUF1635 PF07795.11 CDJ59966.1 - 0.22 11.3 10.0 0.28 11.0 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) EphA2_TM PF14575.6 CDJ59966.1 - 0.41 11.6 4.4 0.53 11.2 4.4 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EIF4E-T PF10477.9 CDJ59966.1 - 0.59 8.9 11.1 0.65 8.7 11.1 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Lin-8 PF03353.15 CDJ59966.1 - 1.2 8.6 7.1 1.3 8.5 7.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2722 PF10846.8 CDJ59966.1 - 1.5 7.7 16.9 1.7 7.5 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Vasculin PF15337.6 CDJ59966.1 - 1.9 9.4 9.4 2.3 9.1 9.4 1.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 SUIM_assoc PF16619.5 CDJ59968.1 - 0.0068 16.5 12.7 0.0068 16.5 12.7 22.2 12 8 5 17 17 17 2 Unstructured region C-term to UIM in Ataxin3 DUF2541 PF10807.8 CDJ59968.1 - 0.0099 16.0 0.7 0.021 14.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2541) SUIM_assoc PF16619.5 CDJ59969.1 - 0.025 14.7 68.4 0.033 14.3 9.2 4.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RP-C_C PF11800.8 CDJ59969.1 - 0.38 10.8 11.6 0.31 11.1 7.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region SPX PF03105.19 CDJ59969.1 - 0.64 9.9 10.2 0.9 9.4 10.2 1.1 1 0 0 1 1 1 0 SPX domain NINJA_B PF16136.5 CDJ59969.1 - 5.6 7.4 14.9 6.1 7.3 1.2 3.1 3 0 0 3 3 3 0 Putative nuclear localisation signal TFIIA PF03153.13 CDJ59970.1 - 0.00015 21.9 32.6 0.00017 21.8 32.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDJ59970.1 - 0.00048 20.1 15.3 0.00054 19.9 15.3 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SR-25 PF10500.9 CDJ59970.1 - 0.00092 18.9 28.6 0.00092 18.9 28.6 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PNISR PF15996.5 CDJ59970.1 - 0.0024 18.2 23.6 0.0033 17.7 23.6 1.2 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR CDC45 PF02724.14 CDJ59970.1 - 0.0033 15.8 21.4 0.0038 15.6 21.4 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF2052 PF09747.9 CDJ59970.1 - 0.0055 16.9 15.9 0.0067 16.6 15.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Peptidase_S30 PF01577.16 CDJ59970.1 - 0.0087 15.7 20.1 0.012 15.3 20.1 1.3 1 0 0 1 1 1 1 Potyvirus P1 protease RR_TM4-6 PF06459.12 CDJ59970.1 - 0.065 13.1 23.2 0.11 12.3 23.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CDJ59970.1 - 0.079 12.0 21.7 0.09 11.8 21.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Orf78 PF06024.12 CDJ59970.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.5 2 1 1 3 3 3 0 Orf78 (ac78) Draxin PF15550.6 CDJ59970.1 - 0.11 12.4 21.9 0.14 12.1 21.9 1.0 1 0 0 1 1 1 0 Draxin DUF572 PF04502.13 CDJ59970.1 - 0.22 11.1 26.9 0.3 10.7 26.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ALMT PF11744.8 CDJ59970.1 - 0.63 8.8 16.9 0.78 8.5 16.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CDJ59970.1 - 0.65 8.7 15.5 0.84 8.4 15.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MCU PF04678.13 CDJ59970.1 - 0.89 9.6 12.5 4.4 7.4 5.5 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter LAP1C PF05609.12 CDJ59970.1 - 1 8.4 26.7 0.65 9.0 25.4 1.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Smg8_Smg9 PF10220.9 CDJ59970.1 - 1.6 7.0 22.0 1.8 6.8 22.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Dicty_REP PF05086.12 CDJ59970.1 - 1.9 6.4 19.0 2.1 6.3 19.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.9 CDJ59970.1 - 2.4 6.3 28.2 2.6 6.2 28.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.11 CDJ59970.1 - 4.1 5.8 30.8 5.2 5.4 30.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.9 CDJ59970.1 - 5.2 5.5 28.7 6.8 5.1 28.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF3452 PF11934.8 CDJ59970.1 - 7.3 6.2 11.9 0.33 10.5 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4407 PF14362.6 CDJ59970.1 - 7.7 5.8 25.1 9.5 5.5 25.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sterol-sensing PF12349.8 CDJ59971.1 - 8.1e-06 25.7 2.7 8.1e-06 25.7 2.7 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDJ59971.1 - 0.0012 17.0 0.1 0.0012 17.0 0.1 1.9 2 0 0 2 2 2 1 Patched family BAF1_ABF1 PF04684.13 CDJ59971.1 - 0.81 8.7 33.3 0.004 16.3 13.7 3.3 2 1 1 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.19 CDJ59971.1 - 1.8 9.2 41.2 5 7.8 9.4 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nucleoside_tran PF01733.18 CDJ59976.1 - 1.2e-15 57.7 11.9 1.8e-15 57.1 11.9 1.2 1 0 0 1 1 1 1 Nucleoside transporter EMP24_GP25L PF01105.24 CDJ59976.1 - 0.023 14.6 0.7 0.061 13.3 0.7 1.8 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Ycf70 PF17382.2 CDJ59976.1 - 1.4 9.4 3.8 37 4.8 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized Ycf70-like RRM_1 PF00076.22 CDJ59978.1 - 5.8e-08 32.4 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM PF01423.22 CDJ59979.1 - 4.9e-15 55.0 0.6 4.9e-15 55.0 0.6 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 CDJ59979.1 - 0.095 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Hfq protein IMCp PF12314.8 CDJ59980.1 - 6.5e-31 106.5 91.3 8e-19 67.7 38.9 4.3 1 1 3 4 4 4 4 Inner membrane complex protein IMCp PF12314.8 CDJ59981.1 - 5.2e-26 90.8 62.8 9.6e-26 89.9 40.8 5.8 3 2 2 5 5 5 2 Inner membrane complex protein NAD_binding_4 PF07993.12 CDJ59982.1 - 2.4e-54 184.2 0.0 4.1e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sulfotransfer_3 PF13469.6 CDJ59982.1 - 7.1e-25 88.7 0.1 2.5e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 Sulfotransferase family PP-binding PF00550.25 CDJ59982.1 - 6.9e-12 45.6 0.0 2.9e-11 43.5 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sulfotransfer_1 PF00685.27 CDJ59982.1 - 8.4e-12 45.1 0.3 3.9e-11 42.9 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Epimerase PF01370.21 CDJ59982.1 - 3.2e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Syntaxin-6_N PF09177.11 CDJ59982.1 - 0.1 13.2 0.1 5.3 7.7 0.1 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1331 PF07048.11 CDJ59982.1 - 0.11 12.2 0.2 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Pribosyltran_N PF13793.6 CDJ59984.1 - 1.7e-47 160.1 0.1 7e-47 158.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDJ59984.1 - 6.2e-35 120.9 1.5 1.2e-34 119.9 1.5 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain AAA PF00004.29 CDJ59984.1 - 2.4e-13 50.7 0.0 1.2e-11 45.1 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.27 CDJ59984.1 - 2.5e-13 49.9 0.2 5.3e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain BCS1_N PF08740.11 CDJ59984.1 - 6.6e-08 32.7 0.0 6.6e-08 32.7 0.0 1.9 2 0 0 2 2 1 1 BCS1 N terminal AAA_11 PF13086.6 CDJ59984.1 - 0.00028 20.8 3.2 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ59984.1 - 0.00071 20.0 2.0 0.0016 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain UPRTase PF14681.6 CDJ59984.1 - 0.0023 17.4 0.0 0.006 16.0 0.0 1.7 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_5 PF07728.14 CDJ59984.1 - 0.034 14.1 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDJ59984.1 - 0.048 13.8 2.5 0.053 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDJ59984.1 - 0.068 13.6 0.0 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 CDJ59984.1 - 0.091 12.3 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ59984.1 - 0.34 11.4 2.8 0.53 10.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CDJ59984.1 - 7.7 7.0 12.0 72 3.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SARAF PF06682.12 CDJ59986.1 - 0.001 18.8 0.4 0.001 18.8 0.4 11.6 7 4 5 12 12 12 1 SOCE-associated regulatory factor of calcium homoeostasis HIRA_B PF09453.10 CDJ59986.1 - 0.0012 18.6 0.1 0.0045 16.8 0.1 2.1 1 0 0 1 1 1 1 HIRA B motif FHIPEP PF00771.20 CDJ59986.1 - 0.0012 17.4 8.5 0.0012 17.4 8.5 6.6 7 1 2 9 9 9 1 FHIPEP family ANAPC4_WD40 PF12894.7 CDJ59986.1 - 0.015 15.6 0.1 0.16 12.3 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4079 PF13301.6 CDJ59986.1 - 4.7 7.4 6.5 2.6 8.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) AAA_23 PF13476.6 CDJ59987.1 - 0.0012 19.4 10.6 0.0017 18.9 10.6 1.3 1 0 0 1 1 1 1 AAA domain TFIIA PF03153.13 CDJ59987.1 - 0.013 15.6 21.3 0.015 15.3 21.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GPCR_chapero_1 PF11904.8 CDJ59987.1 - 0.09 12.2 8.7 0.13 11.6 8.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone DDHD PF02862.17 CDJ59987.1 - 0.18 11.9 6.7 0.23 11.6 6.7 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CDJ59987.1 - 0.35 8.7 13.0 0.4 8.6 13.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CDJ59987.1 - 0.9 9.0 16.1 1.1 8.7 16.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PTPRCAP PF15713.5 CDJ59987.1 - 1 9.6 15.3 1.9 8.8 15.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Hid1 PF12722.7 CDJ59987.1 - 1.2 7.2 11.5 1.5 6.9 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 CDJ59987.1 - 1.3 8.8 9.4 1.7 8.3 9.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CDJ59987.1 - 1.8 8.5 9.4 2.3 8.2 9.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 CDJ59987.1 - 2 9.6 7.1 3 9.0 7.1 1.2 1 0 0 1 1 1 0 Cdc42 effector Hydin_ADK PF17213.3 CDJ59987.1 - 2.1 8.6 8.1 2.9 8.1 8.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SLC12 PF03522.15 CDJ59987.1 - 3.1 6.7 16.2 4.2 6.3 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 CDJ59987.1 - 5.5 6.3 12.5 8.2 5.7 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Membralin PF09746.9 CDJ59987.1 - 6.7 5.7 9.5 8.5 5.3 9.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 CDJ59987.1 - 7.7 5.2 15.5 10 4.8 15.5 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 CDJ59987.1 - 9.2 5.1 13.1 12 4.7 13.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF2076 PF09849.9 CDJ59988.1 - 1.2 9.1 4.8 1.4 8.9 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L3 PF00297.22 CDJ59989.1 - 4.1e-12 45.8 5.2 2.2e-09 36.8 2.7 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 DUF4637 PF15470.6 CDJ59991.1 - 0.001 18.8 1.2 0.77 9.5 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4637) SH2_2 PF14633.6 CDJ59991.1 - 0.0025 17.3 0.5 2.5 7.4 0.1 2.5 2 0 0 2 2 2 2 SH2 domain E2R135 PF11570.8 CDJ59991.1 - 0.0026 18.1 0.4 3.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Coiled-coil receptor-binding R-domain of colicin E2 DUF1041 PF06292.17 CDJ59991.1 - 0.16 12.3 0.6 7.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) ArsA_ATPase PF02374.15 CDJ59991.1 - 5 6.2 5.9 17 4.5 0.4 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase K_channel_TID PF07941.11 CDJ59992.1 - 0.014 15.8 2.0 0.014 15.8 2.0 7.0 4 2 2 6 6 6 0 Potassium channel Kv1.4 tandem inactivation domain GCV_T PF01571.21 CDJ59993.1 - 1.3e-11 44.4 0.0 1.3e-07 31.2 0.0 2.8 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain DUF4179 PF13786.6 CDJ59993.1 - 0.051 14.1 0.0 1.5e+02 2.9 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) U3_snoRNA_assoc PF08297.11 CDJ59993.1 - 0.64 10.8 4.9 3.6 8.4 1.7 2.9 2 0 0 2 2 2 0 U3 snoRNA associated DUF2722 PF10846.8 CDJ59994.1 - 4.8e-05 22.5 3.9 4.9e-05 22.5 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ59994.1 - 0.00045 19.1 9.6 0.00049 18.9 9.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 CDJ59994.1 - 0.0012 18.9 7.0 0.0012 18.9 7.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit WW_FCH_linker PF16623.5 CDJ59994.1 - 0.0069 17.1 0.1 0.01 16.6 0.1 1.2 1 0 0 1 1 1 1 Unstructured linker region between on GAS7 protein Spt20 PF12090.8 CDJ59994.1 - 0.0076 15.9 13.9 0.0086 15.7 13.9 1.1 1 0 0 1 1 1 1 Spt20 family Suf PF05843.14 CDJ59994.1 - 0.026 14.5 2.8 0.032 14.2 2.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 CDJ59994.1 - 0.027 13.7 7.4 0.028 13.6 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NPBW PF15180.6 CDJ59994.1 - 0.031 14.1 0.2 0.049 13.5 0.2 1.2 1 0 0 1 1 1 0 Neuropeptides B and W UPF0560 PF10577.9 CDJ59994.1 - 0.051 12.1 2.4 0.054 12.0 2.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Activator_LAG-3 PF11498.8 CDJ59994.1 - 0.16 10.9 20.8 0.2 10.6 20.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CrgA PF06781.12 CDJ59994.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Cell division protein CrgA DUF3337 PF11816.8 CDJ59994.1 - 0.19 11.5 2.2 0.27 11.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF4834 PF16118.5 CDJ59994.1 - 0.23 12.4 4.9 0.35 11.8 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MACPF PF01823.19 CDJ59996.1 - 3.3e-44 151.5 0.1 3.3e-44 151.5 0.1 3.1 4 1 0 4 4 4 1 MAC/Perforin domain Ndc1_Nup PF09531.10 CDJ59996.1 - 0.29 9.8 4.8 0.47 9.1 4.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IATP PF04568.12 CDJ59996.1 - 2.2 8.8 7.0 8.9 6.8 7.0 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP CAF1C_H4-bd PF12265.8 CDJ59997.1 - 2.4e-22 79.0 0.2 5.2e-22 77.9 0.2 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDJ59997.1 - 0.00011 23.0 3.3 5.6 8.0 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Apt1 PF10351.9 CDJ59997.1 - 0.021 13.7 4.9 0.027 13.3 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CDJ59997.1 - 0.13 10.8 7.7 0.18 10.4 7.7 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CDJ59997.1 - 0.74 8.5 5.1 1 8.1 5.1 1.1 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 CDJ59997.1 - 1.1 7.4 5.5 1.6 7.0 5.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF1645 PF07816.11 CDJ59997.1 - 1.5 9.3 17.5 2.9 8.4 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Menin PF05053.13 CDJ59997.1 - 3.5 5.9 8.1 6.1 5.1 8.1 1.3 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 CDJ59997.1 - 3.9 4.5 6.5 5.1 4.1 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ59997.1 - 4.1 6.9 19.9 6.9 6.2 19.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CDJ59997.1 - 5.8 5.1 15.8 8 4.6 15.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol3_delta2 PF13177.6 CDJ59998.1 - 2.6e-09 37.1 0.0 1.6e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 CDJ59998.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDJ59998.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CDJ59998.1 - 0.058 13.8 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ59998.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_S26e PF01283.19 CDJ59998.1 - 0.081 13.4 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S26e PGK PF00162.19 CDJ59999.1 - 1.5e-116 389.5 0.0 2e-116 389.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-CCHC_3 PF13917.6 CDJ60000.1 - 4.4e-18 65.0 2.6 1.3e-17 63.4 2.6 1.9 1 0 0 1 1 1 1 Zinc knuckle RAP1 PF07218.11 CDJ60000.1 - 1.3 7.2 53.8 1.3 7.2 17.4 2.4 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) PhoR PF11808.8 CDJ60001.1 - 2.2 8.8 10.6 7.7 7.0 1.0 6.6 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR DUF2722 PF10846.8 CDJ60002.1 - 8.9e-05 21.6 0.5 0.001 18.1 5.4 6.5 4 3 2 6 6 6 2 Protein of unknown function (DUF2722) SPX PF03105.19 CDJ60002.1 - 0.016 15.2 0.0 0.016 15.2 0.0 4.3 2 1 1 3 3 3 0 SPX domain MDM31_MDM32 PF08118.11 CDJ60002.1 - 0.25 10.0 4.0 0.87 8.2 4.0 1.9 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Arm PF00514.23 CDJ60002.1 - 6.2 7.0 12.1 2.8 8.1 0.2 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TSSC4 PF15264.6 CDJ60003.1 - 0.029 14.6 1.6 0.045 14.0 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 MCM_bind PF09739.9 CDJ60003.1 - 1.3 7.3 4.3 2.2 6.6 4.3 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HC2 PF07382.11 CDJ60004.1 - 5e-09 36.5 132.9 1.2e-06 28.8 59.7 6.2 1 1 5 7 7 7 4 Histone H1-like nucleoprotein HC2 TPR_19 PF14559.6 CDJ60005.1 - 7.3e-13 48.8 9.9 1.5e-05 25.4 0.1 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ60005.1 - 1e-07 32.2 14.0 0.12 13.2 0.8 6.0 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60005.1 - 2.4e-07 30.4 4.4 0.02 14.9 0.5 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60005.1 - 6.2e-06 25.8 0.8 0.13 12.2 0.2 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60005.1 - 1.5e-05 24.8 0.5 1.5 9.2 0.0 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ60005.1 - 8.1e-05 22.2 0.6 0.61 9.8 0.1 3.6 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 CDJ60005.1 - 0.00042 20.4 2.7 4.7 7.4 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ60005.1 - 0.00059 20.0 0.1 6 7.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60005.1 - 0.0018 18.2 4.4 3.7 7.8 0.2 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ60005.1 - 0.016 15.1 2.5 0.041 13.8 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 CDJ60005.1 - 0.048 13.9 1.8 4.3 7.8 0.1 3.9 3 1 0 3 3 3 0 PPR repeat CdiI_N PF18228.1 CDJ60005.1 - 0.05 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 CdiI N-terminal domain Nterm_IS4 PF13006.7 CDJ60005.1 - 0.087 13.0 0.2 0.38 11.0 0.0 2.1 3 0 0 3 3 2 0 Insertion element 4 transposase N-terminal TPR_12 PF13424.6 CDJ60005.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDJ60005.1 - 5.4 7.4 13.6 4.8 7.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HA2 PF04408.23 CDJ60006.1 - 4.9e-18 65.4 1.1 4.6e-17 62.2 0.0 3.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ60006.1 - 1.8e-17 63.4 0.0 4.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ60006.1 - 9.4e-12 45.3 0.0 2.1e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ60006.1 - 4.7e-05 23.2 0.6 0.00074 19.3 0.6 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDJ60006.1 - 0.00036 20.8 0.1 0.0019 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDJ60006.1 - 0.00065 18.8 0.0 0.0019 17.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CDJ60006.1 - 0.055 13.8 0.4 0.55 10.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDJ60006.1 - 0.1 12.7 0.0 9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ60006.1 - 0.13 12.7 0.4 0.58 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDJ60006.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Ribosomal_60s PF00428.19 CDJ60008.1 - 0.025 15.2 5.8 0.025 15.2 5.8 4.4 2 2 2 4 4 4 0 60s Acidic ribosomal protein TMEM51 PF15345.6 CDJ60008.1 - 0.15 11.9 14.4 0.38 10.6 14.4 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 CDJ60008.1 - 3.1 7.4 20.0 0.77 9.3 17.1 1.5 2 0 0 2 2 2 0 Spt20 family tRNA-synt_1 PF00133.22 CDJ60009.1 - 2.3e-53 181.4 0.5 4.3e-42 144.2 3.7 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDJ60009.1 - 9.4e-07 27.9 0.2 0.014 14.2 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DUF4667 PF15700.5 CDJ60011.1 - 0.012 15.7 5.6 0.014 15.5 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) AF-4 PF05110.13 CDJ60011.1 - 0.04 12.0 14.5 0.041 12.0 14.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 CDJ60011.1 - 0.17 10.4 5.7 0.21 10.1 5.7 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ60011.1 - 0.21 10.4 3.9 0.21 10.4 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDJ60011.1 - 0.43 9.3 2.0 0.5 9.1 2.0 1.1 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 CDJ60011.1 - 0.47 10.1 12.5 0.56 9.9 12.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 BUD22 PF09073.10 CDJ60011.1 - 0.52 9.6 10.7 0.67 9.2 10.7 1.1 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 CDJ60011.1 - 4.9 7.0 11.2 5.8 6.7 11.2 1.1 1 0 0 1 1 1 0 SPX domain RskA PF10099.9 CDJ60014.1 - 0.00024 21.5 0.8 0.00069 20.0 0.8 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA PCI PF01399.27 CDJ60014.1 - 0.00096 19.6 0.1 0.00096 19.6 0.1 2.7 3 1 0 3 3 3 1 PCI domain FbpA PF05833.11 CDJ60014.1 - 0.0019 17.1 3.9 0.0027 16.6 3.9 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) TFIIA PF03153.13 CDJ60014.1 - 0.075 13.0 14.1 0.098 12.6 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3245 PF11595.8 CDJ60014.1 - 0.28 11.7 8.0 0.45 11.0 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 CDJ60014.1 - 3.8 8.2 8.8 0.54 10.9 4.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Exonuc_VII_L PF02601.15 CDJ60015.1 - 0.011 15.3 19.8 0.02 14.5 19.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lipase PF00151.19 CDJ60015.1 - 0.24 10.6 6.5 0.4 9.9 6.5 1.3 1 0 0 1 1 1 0 Lipase Neur_chan_memb PF02932.16 CDJ60015.1 - 2.1 8.4 12.7 0.47 10.5 8.4 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PAF-AH_p_II PF03403.13 CDJ60015.1 - 4.3 5.7 10.8 6.1 5.2 9.2 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PIH1_CS PF18201.1 CDJ60016.1 - 1.7e-08 34.8 0.1 4.9e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain Band_3_cyto PF07565.13 CDJ60017.1 - 1.6 8.5 9.0 6.7 6.4 0.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.8 CDJ60017.1 - 1.9 8.0 28.5 3.5 7.2 16.5 2.3 2 0 0 2 2 2 0 Spt20 family MTP18 PF10558.9 CDJ60020.1 - 0.65 9.9 1.9 0.64 10.0 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Rrn6 PF10214.9 CDJ60020.1 - 1.5 7.3 21.2 1.5 7.2 21.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EOS1 PF12326.8 CDJ60020.1 - 2.3 8.1 8.4 2.9 7.8 8.4 1.1 1 0 0 1 1 1 0 N-glycosylation protein Pal1 PF08316.11 CDJ60020.1 - 2.9 8.6 7.1 3.8 8.3 7.1 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein CLN3 PF02487.17 CDJ60020.1 - 3.7 6.5 9.0 3.2 6.7 9.0 1.2 1 0 0 1 1 1 0 CLN3 protein DDHD PF02862.17 CDJ60020.1 - 5.3 7.1 13.2 5.8 7.0 13.2 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 CDJ60020.1 - 6 6.8 10.7 6 6.8 10.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 CDJ60020.1 - 6.1 5.5 5.0 5.1 5.7 5.0 1.2 1 0 0 1 1 1 0 Ureide permease V_ATPase_I PF01496.19 CDJ60020.1 - 6.6 4.5 14.3 5.6 4.8 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYDLN_acid PF09538.10 CDJ60020.1 - 6.8 7.4 13.0 2.9 8.6 10.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 CDJ60020.1 - 7.2 6.3 19.4 7.8 6.2 19.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ60020.1 - 7.3 6.3 12.6 7.6 6.3 12.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 CDJ60020.1 - 7.4 5.3 8.8 6.3 5.5 8.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Surface_antigen PF11054.8 CDJ60022.1 - 1.4e-13 51.1 1.1 9.5e-13 48.4 0.5 2.0 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen MRP-S31 PF15433.6 CDJ60024.1 - 0.58 9.8 25.8 0.75 9.4 25.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Hamartin PF04388.12 CDJ60024.1 - 8.4 4.9 26.7 9.6 4.7 26.7 1.0 1 0 0 1 1 1 0 Hamartin protein Surface_antigen PF11054.8 CDJ60025.1 - 2.6e-12 47.0 0.3 4.7e-12 46.1 0.3 1.5 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen CDK2AP PF09806.9 CDJ60025.1 - 6.2 6.8 10.0 14 5.7 10.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CSTF1_dimer PF16699.5 CDJ60027.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Asparaginase_C PF17763.1 CDJ60027.1 - 0.075 13.3 1.0 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DUF1073 PF06381.11 CDJ60028.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Amino_oxidase PF01593.24 CDJ60029.1 - 3.2e-40 138.8 15.7 2.4e-24 86.5 0.1 5.9 4 2 1 5 5 5 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ60029.1 - 3.8e-14 52.7 0.6 3.8e-14 52.7 0.6 3.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CDJ60029.1 - 0.0011 19.4 0.4 0.014 15.9 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ60029.1 - 0.0051 16.1 1.3 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.21 CDJ60029.1 - 0.013 14.9 1.7 1.5 8.1 0.1 4.6 3 1 0 3 3 3 0 ThiF family N6_N4_Mtase PF01555.18 CDJ60030.1 - 0.068 12.9 0.0 49 3.5 2.3 3.1 2 1 0 2 2 2 0 DNA methylase Spt20 PF12090.8 CDJ60031.1 - 0.03 13.9 65.3 0.44 10.1 9.7 4.8 4 0 0 4 4 4 0 Spt20 family Mem_trans PF03547.18 CDJ60031.1 - 0.32 9.4 2.1 0.5 8.7 2.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Trp_oprn_chp PF09534.10 CDJ60033.1 - 0.06 13.1 21.8 0.28 11.0 1.7 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Presenilin PF01080.17 CDJ60034.1 - 2.4 6.9 4.7 2.5 6.8 4.7 1.0 1 0 0 1 1 1 0 Presenilin MMU163 PF17119.5 CDJ60034.1 - 2.5 7.2 5.4 2.7 7.1 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis ACC_central PF08326.12 CDJ60034.1 - 7.1 4.7 8.8 7.5 4.6 8.8 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region SPX PF03105.19 CDJ60034.1 - 7.3 6.4 19.5 7.6 6.3 19.5 1.0 1 0 0 1 1 1 0 SPX domain RRN3 PF05327.11 CDJ60035.1 - 0.089 11.3 2.1 0.09 11.3 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 CDJ60035.1 - 0.17 10.0 6.8 0.19 9.9 6.8 1.0 1 0 0 1 1 1 0 Nop14-like family FF PF01846.19 CDJ60036.1 - 6e-10 39.1 0.0 6e-10 39.1 0.0 2.7 3 0 0 3 3 3 1 FF domain TetR_C_11 PF16859.5 CDJ60036.1 - 0.00055 20.2 0.0 0.00099 19.4 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 CDJ60036.1 - 0.059 13.6 0.9 0.96 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Adeno_E4 PF05385.11 CDJ60036.1 - 0.099 12.7 0.3 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein Kelch_3 PF13415.6 CDJ60037.1 - 0.0001 22.5 1.5 0.00046 20.4 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDJ60037.1 - 0.00011 22.0 0.0 0.00039 20.3 0.0 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CDJ60037.1 - 0.00016 21.5 0.0 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CDJ60037.1 - 0.0004 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ60037.1 - 0.019 15.3 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Kelch motif RskA PF10099.9 CDJ60039.1 - 0.00023 21.5 8.1 0.00023 21.5 8.1 3.5 2 1 1 3 3 3 1 Anti-sigma-K factor rskA EIF4E-T PF10477.9 CDJ60039.1 - 0.00082 18.3 0.7 0.002 17.1 0.2 1.4 1 1 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E His_Phos_1 PF00300.22 CDJ60039.1 - 0.0051 16.5 9.9 0.23 11.1 1.4 3.9 3 2 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF4834 PF16118.5 CDJ60039.1 - 0.049 14.6 2.3 0.049 14.6 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 CDJ60039.1 - 0.098 12.8 3.9 1.7 8.8 0.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FIT1_2 PF17357.2 CDJ60039.1 - 0.5 10.5 6.2 0.42 10.7 1.7 2.5 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 HGTP_anticodon2 PF12745.7 CDJ60039.1 - 1 8.8 7.7 0.61 9.6 3.7 2.2 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs FAM176 PF14851.6 CDJ60039.1 - 1.1 8.9 5.0 9.3 5.9 0.6 2.3 2 0 0 2 2 2 0 FAM176 family LRR19-TM PF15176.6 CDJ60039.1 - 3.7 7.6 4.7 1.2 9.1 0.5 2.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Ctr PF04145.15 CDJ60039.1 - 6.4 7.4 6.1 1 10.0 0.5 2.3 2 1 0 2 2 2 0 Ctr copper transporter family AAA PF00004.29 CDJ60040.1 - 1.3e-31 109.7 0.0 1.8e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ60040.1 - 1.3e-06 28.5 0.3 5.3e-06 26.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ60040.1 - 2.2e-05 24.2 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ60040.1 - 3.3e-05 24.3 0.0 0.00055 20.4 0.1 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CDJ60040.1 - 0.00033 20.8 0.0 0.00065 19.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDJ60040.1 - 0.0005 20.4 0.4 0.0052 17.1 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ60040.1 - 0.00074 19.7 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ60040.1 - 0.00097 19.7 0.1 0.0018 18.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDJ60040.1 - 0.0028 17.4 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ60040.1 - 0.003 17.8 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ60040.1 - 0.0033 16.9 0.2 0.0069 15.8 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FoP_duplication PF13865.6 CDJ60040.1 - 0.004 17.7 0.9 0.0061 17.1 0.9 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 AAA_24 PF13479.6 CDJ60040.1 - 0.0045 16.7 0.0 0.0068 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CDJ60040.1 - 0.0045 16.8 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CDJ60040.1 - 0.0059 16.2 0.1 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDJ60040.1 - 0.0063 16.9 0.0 0.0094 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CDJ60040.1 - 0.0082 15.4 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 CDJ60040.1 - 0.0095 15.7 0.0 0.052 13.2 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CDJ60040.1 - 0.013 15.9 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CDJ60040.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CDJ60040.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 CDJ60040.1 - 0.03 13.8 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 CDJ60040.1 - 0.031 14.3 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDJ60040.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDJ60040.1 - 0.044 13.7 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Flot PF15975.5 CDJ60040.1 - 0.052 13.7 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 Flotillin ADK PF00406.22 CDJ60040.1 - 0.085 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA_7 PF12775.7 CDJ60040.1 - 0.096 12.2 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CDJ60040.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 CDJ60040.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDJ60040.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CDJ60040.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ60041.1 - 2.8e-22 79.7 0.0 4.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CDJ60041.1 - 1.1e-14 54.4 9.6 1.5e-14 54.0 9.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 CDJ60041.1 - 0.0001 22.2 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CDJ60041.1 - 0.0037 16.4 16.3 0.0047 16.1 16.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 CDJ60041.1 - 0.0044 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CDJ60041.1 - 0.0051 16.4 0.0 0.039 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDJ60041.1 - 0.0077 16.3 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDJ60041.1 - 0.023 15.1 0.1 0.059 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 CDJ60041.1 - 0.028 14.2 0.0 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDJ60041.1 - 0.037 14.5 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CDJ60041.1 - 0.28 11.2 0.4 0.48 10.5 0.4 1.3 1 0 0 1 1 1 0 Dynamin family RRM_1 PF00076.22 CDJ60042.1 - 3.7e-23 81.1 0.0 4.2e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ60042.1 - 0.11 12.6 0.0 21 5.3 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif MMR_HSR1 PF01926.23 CDJ60045.1 - 2.4e-16 59.8 0.0 1.7e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 CDJ60045.1 - 1e-15 57.6 13.4 1e-15 57.6 13.4 2.7 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 CDJ60045.1 - 5.8e-08 32.4 0.0 4.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDJ60045.1 - 0.00011 22.2 0.6 0.031 14.2 0.2 3.1 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CDJ60045.1 - 0.0025 17.9 5.5 0.72 9.9 0.1 3.9 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 CDJ60045.1 - 0.0029 17.2 0.1 0.15 11.6 0.0 3.1 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDJ60045.1 - 0.0079 16.6 0.2 0.0079 16.6 0.2 3.3 2 2 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 CDJ60045.1 - 0.078 12.0 0.1 0.2 10.6 0.1 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3086 PF11285.8 CDJ60045.1 - 0.088 11.9 8.9 0.25 10.4 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) PDZ_3 PF17815.1 CDJ60046.1 - 1.7e-36 125.3 1.0 2.3e-27 95.6 0.2 3.0 3 0 0 3 3 3 2 PDZ domain Trypsin_2 PF13365.6 CDJ60046.1 - 2.5e-12 47.9 0.9 6.2e-12 46.7 0.5 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 CDJ60046.1 - 2.8e-06 27.6 1.5 1.1e-05 25.7 0.0 2.6 3 0 0 3 3 3 1 PDZ domain Trypsin PF00089.26 CDJ60046.1 - 1.7e-05 24.7 0.1 3.3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 CDJ60046.1 - 0.024 14.5 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Peptidase_S46 PF10459.9 CDJ60046.1 - 0.49 9.0 2.0 0.31 9.6 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 GAPES3 PF17154.4 CDJ60047.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain FAM176 PF14851.6 CDJ60048.1 - 7 6.3 19.4 3.1 7.5 1.0 3.5 3 0 0 3 3 3 0 FAM176 family WBP-1 PF11669.8 CDJ60049.1 - 0.019 15.6 0.1 6.5 7.4 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF2870 PF11069.8 CDJ60050.1 - 6e-19 68.2 0.8 7.2e-11 42.3 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) RNA_pol_Rpb4 PF03874.16 CDJ60053.1 - 3.4e-09 37.1 0.0 4.6e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Mito_carr PF00153.27 CDJ60055.1 - 8.4e-39 131.4 1.2 1.2e-15 57.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5344 PF17279.2 CDJ60056.1 - 0.075 13.6 0.2 0.25 11.9 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Endonuc-BglII PF09195.11 CDJ60056.1 - 0.29 11.0 0.9 0.49 10.2 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease BglII DHHC PF01529.20 CDJ60057.1 - 1.5e-32 112.5 12.7 1.5e-32 112.5 12.7 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase ABC2_membrane_2 PF12679.7 CDJ60057.1 - 0.071 12.4 0.1 0.071 12.4 0.1 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein Adeno_E3B PF03376.14 CDJ60057.1 - 0.85 9.9 10.3 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Adenovirus E3B protein SBE2 PF17076.5 CDJ60058.1 - 7.3 4.7 6.3 10 4.2 6.3 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation DnaJ PF00226.31 CDJ60059.1 - 4.2e-08 33.2 0.2 1.6e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CDJ60059.1 - 0.21 11.8 6.3 1.3 9.3 0.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L6 PF00347.23 CDJ60060.1 - 3.6e-25 88.4 0.7 1.7e-14 54.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CENP-W PF15510.6 CDJ60060.1 - 0.033 14.4 0.4 2.3 8.5 0.1 2.4 2 0 0 2 2 2 0 CENP-W protein DUF2203 PF09969.9 CDJ60061.1 - 0.073 13.8 0.2 0.46 11.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2228 PF10228.9 CDJ60061.1 - 0.11 12.2 1.1 0.15 11.8 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Phage_lysis PF03245.13 CDJ60061.1 - 0.49 10.5 5.6 0.78 9.9 5.6 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein YabA PF06156.13 CDJ60061.1 - 1.6 9.4 5.4 2.7 8.7 5.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA VTC PF09359.10 CDJ60062.1 - 9.4e-80 267.9 0.0 1.5e-79 267.2 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CDJ60062.1 - 4.7e-05 23.8 0.7 4.7e-05 23.8 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Chloroplast_duf PF14476.6 CDJ60062.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Petal formation-expressed AAA PF00004.29 CDJ60063.1 - 8.9e-87 288.2 0.0 1.5e-46 158.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ60063.1 - 1.6e-23 82.2 13.2 1.3e-13 50.6 0.6 3.4 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CDJ60063.1 - 2.2e-21 75.8 0.8 5e-21 74.7 0.8 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDJ60063.1 - 1e-13 51.4 0.0 5e-06 26.4 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDJ60063.1 - 3.1e-12 46.9 0.0 2.1e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ60063.1 - 4.7e-12 46.6 0.2 0.00052 20.4 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 CDJ60063.1 - 1.3e-10 41.6 0.0 5.5e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ60063.1 - 2.7e-10 40.4 0.2 3.6e-05 23.8 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CDJ60063.1 - 1.4e-09 37.6 0.0 3.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CDJ60063.1 - 7e-09 36.1 0.2 0.073 13.4 0.0 3.8 2 2 2 4 4 3 2 AAA domain TIP49 PF06068.13 CDJ60063.1 - 2.2e-08 33.7 0.1 0.00075 18.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CDJ60063.1 - 5.6e-07 29.2 0.3 0.037 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDJ60063.1 - 5.8e-07 30.1 0.0 0.03 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDJ60063.1 - 9.1e-07 29.2 0.0 0.021 15.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.10 CDJ60063.1 - 9.3e-07 28.8 0.1 0.00052 20.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 CDJ60063.1 - 2.1e-06 27.4 1.3 1.2 8.7 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_14 PF13173.6 CDJ60063.1 - 4.5e-06 26.7 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ60063.1 - 1.2e-05 25.1 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ60063.1 - 2e-05 24.9 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CDJ60063.1 - 3.9e-05 23.7 0.1 0.65 9.9 0.1 3.1 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CDJ60063.1 - 4.6e-05 23.0 0.0 0.35 10.4 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 CDJ60063.1 - 5.6e-05 22.6 0.1 2.6 7.3 0.0 3.3 3 0 0 3 3 3 2 KaiC ABC_tran PF00005.27 CDJ60063.1 - 6.1e-05 23.6 0.1 0.34 11.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 CDJ60063.1 - 6.5e-05 23.4 0.1 0.17 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CDJ60063.1 - 8.3e-05 22.6 0.1 0.17 11.8 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 CDJ60063.1 - 0.0001 22.1 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CDJ60063.1 - 0.00016 21.7 0.0 0.92 9.5 0.0 2.8 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ60063.1 - 0.00022 20.4 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CDJ60063.1 - 0.00039 19.7 0.0 0.87 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 CDJ60063.1 - 0.00061 19.5 0.0 1.4 8.6 0.0 3.4 2 1 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDJ60063.1 - 0.00097 18.5 0.0 0.8 8.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 CDJ60063.1 - 0.00099 19.2 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 CDJ60063.1 - 0.0011 18.2 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CDJ60063.1 - 0.002 18.0 0.0 0.87 9.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein PhoH PF02562.16 CDJ60063.1 - 0.0026 17.2 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 CDJ60063.1 - 0.0027 17.6 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDJ60063.1 - 0.0055 16.6 0.0 2.3 8.1 0.0 2.8 2 1 1 3 3 2 1 Rad17 P-loop domain ResIII PF04851.15 CDJ60063.1 - 0.0067 16.4 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CDJ60063.1 - 0.0069 16.2 0.0 0.72 9.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CDJ60063.1 - 0.0091 15.3 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CDJ60063.1 - 0.016 15.1 1.0 13 5.7 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_19 PF13245.6 CDJ60063.1 - 0.017 15.5 0.8 6.8 7.0 0.1 3.3 3 1 1 4 4 2 0 AAA domain AAA_30 PF13604.6 CDJ60063.1 - 0.024 14.3 0.1 6.5 6.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDJ60063.1 - 0.032 13.5 0.1 3.3 6.8 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain AAA_11 PF13086.6 CDJ60063.1 - 0.036 13.8 0.0 8 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CDJ60063.1 - 0.048 13.8 0.3 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase Cytidylate_kin PF02224.18 CDJ60063.1 - 0.065 12.9 0.1 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 CDJ60063.1 - 0.074 13.2 0.2 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase-like family UFD1 PF03152.14 CDJ60063.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_29 PF13555.6 CDJ60063.1 - 0.22 11.3 2.3 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 CDJ60063.1 - 0.98 9.7 4.0 62 3.8 0.0 4.1 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain HIT PF01230.23 CDJ60065.1 - 1.8e-21 76.7 0.0 2.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDJ60065.1 - 2e-09 37.9 0.0 2.6e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 CDJ60066.1 - 2.4e-37 128.7 0.0 4.8e-12 45.8 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60066.1 - 6.2e-19 68.3 0.0 3.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ60066.1 - 5e-08 31.9 0.0 0.007 15.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDJ60066.1 - 5.2e-07 30.0 0.0 0.07 13.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60066.1 - 4e-06 26.3 0.2 0.13 12.3 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ60066.1 - 3.7e-05 23.0 0.1 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ60066.1 - 0.0022 17.8 0.5 0.15 12.0 0.1 3.1 4 0 0 4 4 4 1 EF-hand domain pair TFIIA PF03153.13 CDJ60066.1 - 0.52 10.2 15.7 0.73 9.8 11.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lipase_3 PF01764.25 CDJ60067.1 - 3.6e-18 65.8 0.0 8.7e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDJ60067.1 - 0.00017 22.3 0.3 0.0065 17.1 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 CDJ60067.1 - 0.0054 16.3 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CDJ60067.1 - 0.032 13.5 0.0 0.091 12.0 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDJ60067.1 - 0.035 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain WD40 PF00400.32 CDJ60068.1 - 1.1e-34 117.9 25.1 4.1e-08 33.7 0.1 8.9 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ60068.1 - 5.6e-09 36.2 0.3 0.0019 18.5 0.0 4.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDJ60068.1 - 7.6e-06 24.9 0.5 1.6 7.3 0.0 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDJ60068.1 - 0.0013 17.8 2.4 1.1 8.1 0.1 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CDJ60068.1 - 0.0088 14.8 0.4 0.17 10.6 0.0 2.4 2 1 1 3 3 3 1 Nup133 N terminal like DUF1513 PF07433.11 CDJ60068.1 - 0.15 11.1 0.8 0.58 9.2 0.2 2.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1513) zn-ribbon_14 PF16503.5 CDJ60069.1 - 0.0096 15.4 2.1 0.02 14.4 0.8 2.2 2 0 0 2 2 2 1 Zinc-ribbon MCM PF00493.23 CDJ60070.1 - 3.2e-59 199.7 0.0 4.9e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDJ60070.1 - 4.3e-23 81.5 3.8 1e-22 80.4 3.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDJ60070.1 - 8.9e-07 28.5 0.1 2.3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDJ60070.1 - 6.9e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDJ60070.1 - 0.0001 22.1 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GntR PF00392.21 CDJ60070.1 - 0.029 14.0 0.0 0.089 12.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Mg_chelatase_C PF13335.6 CDJ60070.1 - 0.057 14.0 1.8 0.43 11.2 1.2 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Glycos_trans_3N PF02885.17 CDJ60070.1 - 0.079 12.8 0.3 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Dabb PF07876.12 CDJ60070.1 - 0.082 13.5 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Sigma54_activat PF00158.26 CDJ60070.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain HxlR PF01638.17 CDJ60070.1 - 0.14 12.0 0.2 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Paf67 PF10255.9 CDJ60071.1 - 1.2e-116 390.1 0.5 1.7e-116 389.6 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CDJ60071.1 - 0.013 15.6 0.0 0.072 13.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2605 PF10792.9 CDJ60071.1 - 0.069 13.1 2.1 0.11 12.4 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) TMEM65 PF10507.9 CDJ60071.1 - 0.075 13.0 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 65 DUF1440 PF07274.12 CDJ60071.1 - 0.17 12.2 0.1 0.36 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) Ribosomal_60s PF00428.19 CDJ60071.1 - 4.8 7.8 19.2 5.1 7.7 14.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ProSAAS PF07259.12 CDJ60071.1 - 7.9 6.4 11.9 1.2e+02 2.5 11.2 2.3 2 0 0 2 2 2 0 ProSAAS precursor Chromo PF00385.24 CDJ60072.1 - 1.8e-08 34.1 0.0 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SLC12 PF03522.15 CDJ60072.1 - 0.005 15.9 12.8 0.005 15.9 12.8 2.8 3 0 0 3 3 3 2 Solute carrier family 12 RNA_pol_Rpb1_5 PF04998.17 CDJ60075.1 - 7.5e-18 64.9 0.2 8.4e-18 64.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Apolipoprotein PF01442.18 CDJ60076.1 - 0.011 15.7 2.0 0.017 15.0 2.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TrbI PF03743.14 CDJ60076.1 - 0.017 15.0 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF1053 PF06327.14 CDJ60076.1 - 0.13 12.8 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF760 PF05542.11 CDJ60076.1 - 0.4 11.1 2.3 0.56 10.6 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF760) Auts2 PF15336.6 CDJ60077.1 - 0.0088 16.2 3.1 0.0088 16.2 3.1 1.7 1 1 0 2 2 2 1 Autism susceptibility gene 2 protein Peptidase_C65 PF10275.9 CDJ60079.1 - 9.8e-35 120.2 11.1 2.5e-33 115.5 11.1 2.6 1 1 0 1 1 1 1 Peptidase C65 Otubain TFIIA PF03153.13 CDJ60079.1 - 0.002 18.2 15.7 0.0027 17.8 15.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 CDJ60079.1 - 0.0077 15.5 6.2 0.014 14.6 6.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 CDJ60079.1 - 0.023 13.7 1.6 0.031 13.3 1.6 1.3 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 CDJ60079.1 - 0.25 10.0 2.1 0.36 9.5 2.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4199 PF13858.6 CDJ60079.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF4199) RIFIN PF02009.16 CDJ60079.1 - 0.58 10.0 8.8 1.1 9.1 8.8 1.5 1 0 0 1 1 1 0 Rifin DUF2368 PF10166.9 CDJ60079.1 - 0.59 9.7 7.3 1.6 8.4 7.3 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) HCO3_cotransp PF00955.21 CDJ60079.1 - 0.74 8.6 3.1 1.1 8.0 3.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family PDDEXK_6 PF04720.12 CDJ60079.1 - 1.1 9.1 8.9 0.076 13.0 2.8 2.0 2 0 0 2 2 2 0 PDDEXK-like family of unknown function CSG2 PF16965.5 CDJ60079.1 - 1.2 8.0 3.3 1.6 7.6 3.3 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator BAF1_ABF1 PF04684.13 CDJ60079.1 - 2 7.4 15.9 3.1 6.8 15.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.22 CDJ60079.1 - 3.4 6.8 4.9 0.29 10.3 0.5 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter EPL1 PF10513.9 CDJ60079.1 - 7.4 6.9 14.9 0.48 10.8 9.0 1.9 1 1 1 2 2 2 0 Enhancer of polycomb-like mTERF PF02536.14 CDJ60080.1 - 1.6e-13 50.3 0.1 2.2e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 mTERF PI3K_1B_p101 PF10486.9 CDJ60080.1 - 0.00081 17.3 4.3 0.00081 17.3 4.3 3.2 3 0 0 3 3 3 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 CDJ60080.1 - 0.0011 18.6 16.0 0.0011 18.6 16.0 3.5 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein RXT2_N PF08595.11 CDJ60080.1 - 0.0022 18.0 1.3 0.0022 18.0 1.3 4.6 3 2 2 5 5 5 1 RXT2-like, N-terminal DUF755 PF05501.11 CDJ60080.1 - 0.0055 17.0 20.2 0.0055 17.0 20.2 4.8 5 1 0 5 5 5 1 Domain of unknown function (DUF755) Otopetrin PF03189.13 CDJ60080.1 - 4.6 6.0 4.3 24 3.6 4.3 2.2 1 1 0 1 1 1 0 Otopetrin IF-2B PF01008.17 CDJ60081.1 - 3.1e-29 102.1 0.0 8.9e-25 87.4 0.0 2.4 1 1 1 2 2 2 2 Initiation factor 2 subunit family SUIM_assoc PF16619.5 CDJ60081.1 - 0.0025 17.9 1.3 0.0025 17.9 1.3 4.6 4 1 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ60081.1 - 0.0031 17.2 9.4 0.0031 17.2 9.4 3.8 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Med15 PF09606.10 CDJ60081.1 - 0.0044 15.8 13.7 0.0044 15.8 13.7 2.4 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal MCU PF04678.13 CDJ60081.1 - 6.7 6.8 6.7 23 5.0 2.2 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter ARS2 PF04959.13 CDJ60082.1 - 4.2e-10 40.3 0.7 8.8e-10 39.3 0.7 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 CDJ60082.1 - 2.6e-09 37.3 0.3 1.1e-08 35.2 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 CDJ60082.1 - 0.0021 17.8 0.4 0.0052 16.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) CDK2AP PF09806.9 CDJ60082.1 - 0.037 14.1 6.5 0.077 13.0 6.5 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Bul1_C PF04426.12 CDJ60082.1 - 0.038 13.4 3.6 0.063 12.7 3.6 1.3 1 0 0 1 1 1 0 Bul1 C terminus DUF1635 PF07795.11 CDJ60082.1 - 0.28 11.0 8.8 0.73 9.7 8.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3915 PF13054.6 CDJ60082.1 - 0.64 10.0 5.9 1.5 8.8 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SMN PF06003.12 CDJ60082.1 - 3.5 6.8 8.3 8.9 5.5 1.1 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) KCNQ2_u3 PF16642.5 CDJ60082.1 - 9.1 7.3 15.8 3.4 8.7 7.8 2.8 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DUF2228 PF10228.9 CDJ60083.1 - 1.9e-20 73.7 5.7 2.8e-19 69.9 0.3 3.1 2 2 2 4 4 4 2 Uncharacterised conserved protein (DUF2228) DUF4518 PF15008.6 CDJ60083.1 - 0.039 13.1 6.5 0.41 9.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) RNA_pol_Rpc82 PF05645.13 CDJ60083.1 - 0.1 12.3 6.6 3.7 7.2 2.2 2.7 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Lin-8 PF03353.15 CDJ60083.1 - 0.21 11.1 17.5 0.44 10.0 7.9 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ60083.1 - 0.27 11.5 45.5 0.023 15.0 3.7 2.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PDGF PF00341.17 CDJ60083.1 - 0.27 11.5 1.8 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 PDGF/VEGF domain Miga PF10265.9 CDJ60083.1 - 5.5 5.9 15.3 1.2 8.1 5.2 2.2 2 0 0 2 2 2 0 Mitoguardin Dicty_REP PF05086.12 CDJ60083.1 - 9.4 4.1 9.4 0.74 7.7 3.6 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein hDGE_amylase PF14701.6 CDJ60084.1 - 2.4e-120 402.6 0.0 1.8e-62 211.8 0.0 2.3 1 1 0 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CDJ60084.1 - 2.6e-48 164.9 0.0 4.1e-29 101.7 0.0 2.9 2 1 1 3 3 3 2 Amylo-alpha-1,6-glucosidase DUF4667 PF15700.5 CDJ60084.1 - 1.1e-06 28.9 4.9 0.00022 21.4 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) Spt20 PF12090.8 CDJ60084.1 - 0.0022 17.7 2.6 0.0022 17.7 2.6 2.3 2 0 0 2 2 2 1 Spt20 family MID_MedPIWI PF18296.1 CDJ60084.1 - 0.11 12.3 6.8 1.2 8.9 0.5 3.3 3 0 0 3 3 3 0 MID domain of medPIWI DUF4050 PF13259.6 CDJ60084.1 - 0.23 11.8 5.3 2.2 8.6 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) TFIIA PF03153.13 CDJ60084.1 - 0.38 10.7 15.2 0.06 13.3 4.1 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CDJ60084.1 - 2.4 6.8 5.0 10 4.7 1.5 2.2 2 0 0 2 2 2 0 Presenilin Tubulin PF00091.25 CDJ60085.1 - 4e-52 177.3 0.0 6.1e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ60085.1 - 5e-51 172.1 0.3 1.4e-50 170.7 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDJ60085.1 - 0.032 13.9 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Ribosomal_L3 PF00297.22 CDJ60086.1 - 5.7e-173 575.1 2.2 6.4e-173 574.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 HemN_C PF06969.16 CDJ60087.1 - 0.06 13.4 0.1 0.06 13.4 0.1 3.2 3 0 0 3 3 3 0 HemN C-terminal domain AAA_23 PF13476.6 CDJ60087.1 - 0.19 12.2 1.4 0.34 11.4 1.4 1.3 1 0 0 1 1 1 0 AAA domain AF-4 PF05110.13 CDJ60087.1 - 1.1 7.3 10.6 2 6.4 10.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sporozoite_P67 PF05642.11 CDJ60087.1 - 2.2 6.2 4.6 7.8 4.4 5.0 1.7 1 1 1 2 2 2 0 Sporozoite P67 surface antigen SPX PF03105.19 CDJ60087.1 - 4.1 7.2 10.6 0.091 12.7 3.9 1.6 2 0 0 2 2 2 0 SPX domain RRM_1 PF00076.22 CDJ60088.1 - 1.6e-13 50.3 0.1 3.7e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ60088.1 - 0.012 15.6 0.0 0.077 13.0 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Methyltransf_25 PF13649.6 CDJ60089.1 - 0.0056 17.4 1.4 0.14 12.9 0.1 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ60089.1 - 0.11 13.2 0.2 4.7 7.9 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDJ60089.1 - 0.67 10.7 0.0 0.67 10.7 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain eIF2_C PF09173.11 CDJ60091.1 - 3.5e-33 113.7 1.0 5.7e-33 113.0 0.2 1.8 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CDJ60091.1 - 1.9e-23 83.0 0.1 2.7e-22 79.2 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDJ60091.1 - 5.3e-11 42.8 0.3 5.3e-11 42.8 0.3 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDJ60091.1 - 0.0036 17.4 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDJ60091.1 - 0.035 14.0 0.3 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Dmrt1 PF12374.8 CDJ60092.1 - 0.83 10.1 8.3 0.46 11.0 0.2 3.0 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Ribosomal_60s PF00428.19 CDJ60092.1 - 3.4 8.3 13.4 6.1 7.5 1.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2057 PF09829.9 CDJ60092.1 - 5.5 7.1 8.4 17 5.5 5.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Helicase_C PF00271.31 CDJ60095.1 - 4.2e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ60095.1 - 2.1e-07 30.8 0.1 6e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CDJ60095.1 - 0.00097 19.3 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SNF2_N PF00176.23 CDJ60096.1 - 2e-68 230.7 0.0 3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 CDJ60096.1 - 2e-07 30.8 3.3 5.4e-07 29.5 3.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ60096.1 - 1.9e-06 27.6 4.8 4.2e-06 26.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ60096.1 - 1.8e-05 24.5 5.4 3.8e-05 23.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDJ60096.1 - 8.3e-05 22.3 6.7 0.0002 21.1 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ60096.1 - 0.00034 20.9 6.0 0.00034 20.9 6.0 2.1 2 0 0 2 2 1 1 Ring finger domain Helicase_C PF00271.31 CDJ60096.1 - 0.0012 19.2 0.0 0.027 14.8 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CDJ60096.1 - 0.0024 17.8 2.7 0.0024 17.8 2.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ60096.1 - 0.018 15.2 7.9 0.044 13.9 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDJ60096.1 - 0.023 14.6 8.2 0.06 13.2 8.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CDJ60096.1 - 0.27 11.1 2.4 0.85 9.5 2.4 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.20 CDJ60096.1 - 2 8.2 6.3 32 4.4 7.2 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Pkinase_Tyr PF07714.17 CDJ60097.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDJ60097.1 - 0.00042 19.8 0.0 0.098 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain HEAT_2 PF13646.6 CDJ60097.1 - 0.094 13.1 5.3 0.11 12.9 2.5 2.5 2 1 1 3 3 3 0 HEAT repeats KinB_sensor PF16767.5 CDJ60098.1 - 0.53 10.8 3.2 0.99 9.9 0.7 2.5 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Etmic-2 PF06670.11 CDJ60099.1 - 2.6e-70 237.3 11.6 2.3e-51 174.9 7.2 2.6 1 1 1 2 2 2 2 Microneme protein Etmic-2 CAP_N PF01213.19 CDJ60104.1 - 7.6 5.9 6.1 8.1 5.8 6.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YL1 PF05764.13 CDJ60106.1 - 9.4e-05 22.6 30.7 0.0001 22.5 30.7 1.0 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 CDJ60106.1 - 0.18 11.2 38.4 0.19 11.1 38.4 1.1 1 0 0 1 1 1 0 SDA1 SARAF PF06682.12 CDJ60106.1 - 0.26 10.9 9.9 0.28 10.8 9.9 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CDC45 PF02724.14 CDJ60106.1 - 0.28 9.4 31.6 0.33 9.2 31.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDJ60106.1 - 0.29 10.9 22.0 0.42 10.4 22.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 CDJ60106.1 - 0.35 11.5 8.9 0.45 11.2 8.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop53 PF07767.11 CDJ60106.1 - 0.64 9.4 35.4 0.94 8.8 35.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LTV PF04180.14 CDJ60106.1 - 0.74 9.5 24.6 0.78 9.4 24.6 1.0 1 0 0 1 1 1 0 Low temperature viability protein BUD22 PF09073.10 CDJ60106.1 - 0.79 9.0 32.0 0.96 8.7 32.0 1.3 1 0 0 1 1 1 0 BUD22 GAGA_bind PF06217.12 CDJ60106.1 - 0.96 9.7 7.9 1.1 9.5 7.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S64 PF08192.11 CDJ60106.1 - 2.1 6.7 11.0 2.2 6.6 11.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 TFIIF_alpha PF05793.12 CDJ60106.1 - 2.3 6.7 41.1 2.8 6.4 41.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 CDJ60106.1 - 2.8 7.4 21.7 3.1 7.3 21.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCSAP PF15748.5 CDJ60106.1 - 3.7 7.6 19.3 4 7.5 19.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PI3K_1B_p101 PF10486.9 CDJ60106.1 - 3.9 5.1 12.7 4.5 4.9 12.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LAP1C PF05609.12 CDJ60106.1 - 4.1 6.4 18.2 4.1 6.4 18.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 CDJ60106.1 - 4.5 5.4 43.3 5.1 5.2 43.3 1.0 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.14 CDJ60106.1 - 5.2 7.0 9.0 5.3 6.9 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Kei1 PF08552.11 CDJ60106.1 - 5.3 6.9 4.1 5.6 6.8 4.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Rrn6 PF10214.9 CDJ60106.1 - 6.1 5.2 12.1 6.6 5.1 12.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Apt1 PF10351.9 CDJ60106.1 - 7.7 5.2 18.0 8 5.2 18.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Drc1-Sld2 PF11719.8 CDJ60106.1 - 9.6 5.6 25.4 11 5.4 25.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SUIM_assoc PF16619.5 CDJ60110.1 - 0.021 14.9 6.9 0.021 14.9 6.9 2.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 CDJ60110.1 - 0.14 11.4 1.9 0.19 10.9 1.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.13 CDJ60110.1 - 0.38 10.7 22.4 0.48 10.4 22.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 CDJ60110.1 - 0.89 7.6 4.4 1.1 7.3 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Transket_pyr PF02779.24 CDJ60113.1 - 1e-58 198.0 0.0 1.4e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDJ60113.1 - 2.5e-46 157.1 0.0 6.9e-46 155.7 0.0 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal BRF1 PF07741.13 CDJ60113.1 - 0.065 13.6 7.2 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LRR_6 PF13516.6 CDJ60114.1 - 9.6e-10 37.7 0.8 0.0026 17.7 0.2 5.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 CDJ60114.1 - 0.004 17.5 2.3 6.5 7.7 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat Activator_LAG-3 PF11498.8 CDJ60114.1 - 0.68 8.8 17.3 1.1 8.1 17.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hydrolase PF00702.26 CDJ60115.1 - 0.002 18.5 0.1 0.062 13.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ60115.1 - 0.017 14.6 0.5 0.18 11.3 0.0 2.8 2 1 0 2 2 2 0 E1-E2 ATPase Guanylate_cyc PF00211.20 CDJ60116.1 - 2.4e-71 239.2 0.0 3.8e-36 124.4 0.0 3.1 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain p25-alpha PF05517.12 CDJ60117.1 - 3.1e-37 128.1 3.1 3.5e-37 128.0 3.1 1.0 1 0 0 1 1 1 1 p25-alpha Toprim_C_rpt PF13368.6 CDJ60117.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat HH_signal PF01085.18 CDJ60117.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain SET PF00856.28 CDJ60118.1 - 1.3e-08 35.4 0.0 5e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 SET domain RsgI_N PF12791.7 CDJ60118.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor N-terminus ISP3_C PF18045.1 CDJ60119.1 - 9.5e-30 102.7 0.1 1.8e-29 101.9 0.1 1.4 2 0 0 2 2 2 1 ISP3 C-terminal ISP1_C PF18161.1 CDJ60119.1 - 6.8e-23 80.7 0.0 8.6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 ISP1 C-terminal Bin3 PF06859.12 CDJ60119.1 - 0.079 13.6 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) DUF789 PF05623.12 CDJ60120.1 - 1.3e-20 74.3 0.1 1.3e-20 74.3 0.1 5.8 6 2 0 6 6 6 1 Protein of unknown function (DUF789) TraE PF05309.11 CDJ60120.1 - 0.16 11.3 0.1 0.37 10.1 0.1 1.6 1 0 0 1 1 1 0 TraE protein Pkinase PF00069.25 CDJ60122.1 - 2.5e-58 197.6 0.7 1.8e-56 191.5 0.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60122.1 - 1.1e-32 113.4 0.4 6.5e-25 87.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.6 CDJ60122.1 - 6.3e-22 77.8 0.7 1.3e-06 28.8 0.0 4.5 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 CDJ60122.1 - 1.1e-21 74.7 4.9 9.7e-06 24.8 0.0 5.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 CDJ60122.1 - 1.4e-18 65.2 2.5 0.0002 21.0 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 CDJ60122.1 - 2.8e-16 58.2 13.5 7.4e-07 28.4 0.0 6.1 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 CDJ60122.1 - 4.2e-10 39.3 3.0 0.092 12.6 0.0 5.0 4 2 2 6 6 6 3 EF-hand domain pair Kdo PF06293.14 CDJ60122.1 - 2.4e-06 27.0 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDJ60122.1 - 0.00013 21.4 0.1 0.14 11.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like SPARC_Ca_bdg PF10591.9 CDJ60122.1 - 0.0048 17.2 0.1 3.2 8.1 0.0 3.9 3 1 1 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDJ60122.1 - 0.032 14.1 0.2 11 6.0 0.0 3.6 4 0 0 4 4 4 0 EF hand Choline_kinase PF01633.20 CDJ60122.1 - 0.049 13.2 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2452 PF10504.9 CDJ60123.1 - 0.0085 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) GIT1_C PF12205.8 CDJ60123.1 - 0.015 15.4 0.6 0.024 14.7 0.6 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Miga PF10265.9 CDJ60123.1 - 0.062 12.3 0.2 0.06 12.3 0.2 1.1 1 0 0 1 1 1 0 Mitoguardin DUF5327 PF17261.2 CDJ60123.1 - 0.29 11.9 5.2 0.47 11.2 5.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5327) Muted PF14942.6 CDJ60123.1 - 0.35 11.2 4.3 0.22 11.9 2.4 1.6 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_C1 PF00112.23 CDJ60125.1 - 1.1e-49 169.4 1.4 1.6e-49 168.9 1.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 CDJ60125.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide DEAD PF00270.29 CDJ60126.1 - 6.4e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ60126.1 - 9.5e-06 25.9 0.0 3.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TTL PF03133.15 CDJ60127.1 - 8e-18 64.6 0.0 1.8e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ60127.1 - 0.00019 20.8 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDJ60127.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp PRIMA1 PF16101.5 CDJ60128.1 - 9.5 6.3 11.9 26 4.9 7.5 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HSBP1 PF06825.12 CDJ60129.1 - 3.1e-09 36.5 0.7 4.4e-09 36.0 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Allexi_40kDa PF05549.11 CDJ60129.1 - 0.07 12.6 0.4 0.082 12.4 0.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein ANAPC_CDC26 PF10471.9 CDJ60129.1 - 0.2 12.5 3.9 0.61 11.0 3.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 EPL1 PF10513.9 CDJ60129.1 - 0.42 11.0 2.8 0.6 10.5 2.8 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Ribosomal_L18p PF00861.22 CDJ60132.1 - 2.7e-22 79.3 3.2 1.3e-21 77.1 3.2 1.9 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Leu_leader PF08054.11 CDJ60132.1 - 1.1 8.9 4.0 0.53 9.9 1.1 2.0 2 0 0 2 2 2 0 Leucine operon leader peptide Spc7 PF08317.11 CDJ60133.1 - 5.1 5.9 17.8 0.054 12.4 5.6 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3522 PF12036.8 CDJ60134.1 - 2.3e-06 28.0 14.2 0.0059 16.9 0.3 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3522) AAA_23 PF13476.6 CDJ60134.1 - 0.44 11.0 12.0 0.95 9.9 12.0 1.5 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 CDJ60134.1 - 0.89 9.7 6.6 4.7 7.3 1.8 2.5 2 0 0 2 2 2 0 DDHD domain YEATS PF03366.16 CDJ60135.1 - 4e-09 36.3 0.0 9.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 YEATS family Nha1_C PF08619.10 CDJ60135.1 - 0.0021 17.4 3.4 0.0025 17.1 3.4 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Endonuclease_NS PF01223.23 CDJ60137.1 - 0.098 12.5 0.0 0.75 9.6 0.0 1.9 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease DUF4217 PF13959.6 CDJ60138.1 - 4.3e-09 36.4 0.0 6.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) TPH PF13868.6 CDJ60139.1 - 1.6e-25 89.4 122.0 2.6e-14 52.5 51.9 3.0 3 0 0 3 3 3 2 Trichohyalin-plectin-homology domain ELO PF01151.18 CDJ60141.1 - 1.6e-48 165.4 22.0 2.1e-48 165.0 22.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-MYND PF01753.18 CDJ60142.1 - 0.0028 17.7 5.8 0.0064 16.6 5.8 1.6 1 0 0 1 1 1 1 MYND finger DUF2722 PF10846.8 CDJ60143.1 - 8.2e-05 21.7 2.9 8.2e-05 21.7 2.9 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CDJ60143.1 - 0.00067 18.8 2.2 0.00067 18.8 2.2 4.0 4 0 0 4 4 4 2 Transcriptional activator LAG-3 SUIM_assoc PF16619.5 CDJ60144.1 - 0.0081 16.2 9.5 0.0081 16.2 9.5 5.6 4 1 1 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 OppC_N PF12911.7 CDJ60145.1 - 0.074 13.0 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Lin-8 PF03353.15 CDJ60145.1 - 0.14 11.7 2.3 0.15 11.6 2.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CDJ60145.1 - 0.16 11.6 11.2 0.25 10.9 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMCp PF12314.8 CDJ60146.1 - 5.6e-11 42.6 58.9 1.2e-08 35.1 37.7 3.3 1 1 2 3 3 3 3 Inner membrane complex protein adh_short PF00106.25 CDJ60147.1 - 9.9e-56 188.3 0.0 3.5e-55 186.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDJ60147.1 - 8.3e-35 120.4 0.1 2.6e-34 118.8 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDJ60147.1 - 1.4e-11 44.6 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CDJ60147.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pkinase PF00069.25 CDJ60148.1 - 2.6e-64 217.1 0.0 3.9e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60148.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ60148.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Vasculin PF15337.6 CDJ60151.1 - 0.13 13.1 0.6 0.13 13.1 0.6 4.1 2 2 2 4 4 4 0 Vascular protein family Vasculin-like 1 RskA PF10099.9 CDJ60152.1 - 0.00052 20.3 48.4 0.1 12.9 8.7 4.2 3 1 1 4 4 4 3 Anti-sigma-K factor rskA Filament_head PF04732.14 CDJ60152.1 - 0.13 13.1 38.2 0.15 12.9 11.6 4.3 4 0 0 4 4 4 0 Intermediate filament head (DNA binding) region DUF3824 PF12868.7 CDJ60152.1 - 0.18 12.5 29.7 1 10.0 0.1 4.3 3 1 0 4 4 4 0 Domain of unknwon function (DUF3824) EphA2_TM PF14575.6 CDJ60152.1 - 1.2 10.1 12.2 4.4 8.3 0.0 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Mito_carr PF00153.27 CDJ60152.1 - 3.6 7.6 9.8 1.7 8.6 0.2 3.3 3 0 0 3 3 3 0 Mitochondrial carrier protein PepSY_2 PF13670.6 CDJ60152.1 - 4.3 7.4 46.7 0.48 10.5 3.1 4.4 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain AAA_17 PF13207.6 CDJ60153.1 - 1e-13 51.9 0.1 1e-13 51.9 0.1 4.0 2 1 2 4 4 4 1 AAA domain ADK PF00406.22 CDJ60153.1 - 1.1e-13 51.5 0.0 1.1e-13 51.5 0.0 2.8 2 1 1 3 3 3 1 Adenylate kinase SUIM_assoc PF16619.5 CDJ60153.1 - 2.5e-08 33.9 9.0 1e-05 25.5 0.1 6.8 1 1 5 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 CDJ60153.1 - 0.00025 20.7 24.0 0.00025 20.7 24.0 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein ASD2 PF08687.11 CDJ60153.1 - 0.0028 17.3 26.4 0.0028 17.3 26.4 2.1 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 DUF3439 PF11921.8 CDJ60153.1 - 0.12 12.4 1.7 0.32 11.0 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RXLR PF16810.5 CDJ60153.1 - 0.47 10.9 18.7 0.038 14.4 8.1 2.5 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity PPP4R2 PF09184.11 CDJ60153.1 - 2.8 7.5 34.1 0.51 9.9 18.0 2.1 2 0 0 2 2 2 0 PPP4R2 Apt1 PF10351.9 CDJ60153.1 - 3.9 6.2 35.1 3.3 6.5 17.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Rad9 PF04139.13 CDJ60154.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad9 Spt20 PF12090.8 CDJ60154.1 - 1.6 8.3 30.3 0.23 11.0 0.5 3.1 3 0 0 3 3 3 0 Spt20 family Snf7 PF03357.21 CDJ60155.1 - 4e-16 59.1 16.6 4e-16 59.1 16.6 4.1 2 2 2 4 4 4 1 Snf7 SR-25 PF10500.9 CDJ60155.1 - 0.17 11.5 27.8 0.049 13.2 12.7 2.7 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ60156.1 - 0.004 17.5 1.2 0.004 17.5 1.2 39.4 9 5 17 26 26 26 3 Anti-sigma-K factor rskA DUF1418 PF07214.12 CDJ60156.1 - 0.15 12.0 1.9 2.6 7.9 0.0 4.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF4179 PF13786.6 CDJ60156.1 - 3.1 8.3 0.0 3.1 8.3 0.0 24.1 23 5 1 24 24 24 0 Domain of unknown function (DUF4179) NPR3 PF03666.13 CDJ60157.1 - 3.9 6.1 6.6 0.16 10.7 0.5 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 EF-hand_1 PF00036.32 CDJ60158.1 - 1.2e-23 80.8 6.1 4.8e-08 32.0 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ60158.1 - 6e-18 65.1 5.7 1.1e-11 44.9 1.8 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60158.1 - 6.3e-18 63.1 2.5 7.3e-06 25.5 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CDJ60158.1 - 4.7e-15 54.3 4.2 1e-06 28.0 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDJ60158.1 - 1.2e-11 44.3 9.6 9.2e-06 25.4 2.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 CDJ60158.1 - 2.3e-07 30.7 3.7 1.7e-05 24.7 1.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ60158.1 - 1.3e-05 25.5 2.4 0.00035 20.9 0.6 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDJ60158.1 - 0.024 15.0 0.9 0.22 11.9 0.2 2.3 2 1 0 2 2 2 0 EF-hand domain TerB PF05099.13 CDJ60158.1 - 0.049 13.6 0.1 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TerB DEK_C PF08766.11 CDJ60158.1 - 0.096 12.6 0.3 0.26 11.2 0.3 1.8 1 0 0 1 1 1 0 DEK C terminal domain EF-hand_10 PF14788.6 CDJ60158.1 - 0.68 9.8 3.6 1.9 8.4 0.5 2.8 2 1 1 3 3 3 0 EF hand DUF4763 PF15960.5 CDJ60159.1 - 0.00077 18.8 3.1 0.00094 18.6 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF1682 PF07946.14 CDJ60159.1 - 0.19 10.9 3.5 0.24 10.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hist_deacetyl PF00850.19 CDJ60161.1 - 1.3e-59 202.2 2.0 4.9e-59 200.3 0.0 2.9 4 0 0 4 4 4 1 Histone deacetylase domain Ank_2 PF12796.7 CDJ60161.1 - 1.6e-10 41.4 0.3 5.8e-07 30.0 0.2 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ60161.1 - 5.1e-09 36.5 2.5 0.00038 21.0 0.5 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ60161.1 - 1.1e-08 35.1 1.3 1.2e-06 28.7 0.3 3.4 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ60161.1 - 1e-06 28.6 2.6 0.082 13.5 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDJ60161.1 - 0.0003 21.1 12.7 0.0016 18.8 0.8 4.2 4 0 0 4 4 4 2 Ankyrin repeat DDRGK PF09756.9 CDJ60162.1 - 1.2e-37 129.3 20.7 1.2e-37 129.3 20.7 2.7 1 1 0 2 2 2 1 DDRGK domain SR-25 PF10500.9 CDJ60162.1 - 0.0036 16.9 15.5 0.0059 16.3 15.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ60162.1 - 0.0041 17.2 4.0 0.0041 17.2 4.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 CDJ60162.1 - 0.028 14.1 5.6 0.042 13.5 5.6 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SfLAP PF11139.8 CDJ60162.1 - 0.037 13.5 0.7 0.064 12.7 0.7 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein HemY_N PF07219.13 CDJ60162.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.3 1 1 2 3 3 2 0 HemY protein N-terminus BAT2_N PF07001.11 CDJ60162.1 - 0.28 11.6 11.8 0.4 11.1 11.8 1.2 1 0 0 1 1 1 0 BAT2 N-terminus Ndc1_Nup PF09531.10 CDJ60162.1 - 0.29 9.8 1.9 0.33 9.6 1.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 CDJ60162.1 - 0.36 9.8 10.4 0.51 9.3 10.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4778 PF16008.5 CDJ60162.1 - 0.41 10.7 6.4 0.49 10.4 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) VIR_N PF15912.5 CDJ60162.1 - 0.87 9.1 3.9 1.3 8.6 3.9 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal SRP-alpha_N PF04086.13 CDJ60162.1 - 0.93 9.4 14.3 1.3 8.9 14.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_memb PF02932.16 CDJ60162.1 - 1.2 9.1 2.8 2.1 8.3 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 CDJ60162.1 - 1.3 9.5 5.0 1.8 9.1 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 CDJ60162.1 - 4.6 5.9 13.0 0.36 9.6 8.4 1.6 2 0 0 2 2 2 0 Presenilin RskA PF10099.9 CDJ60162.1 - 9.5 6.5 26.6 0.16 12.2 12.0 2.8 1 1 1 2 2 1 0 Anti-sigma-K factor rskA RXLR PF16810.5 CDJ60162.1 - 9.8 6.6 14.3 1.7 9.1 8.8 2.3 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Abhydrolase_1 PF00561.20 CDJ60163.1 - 0.0003 20.5 0.4 0.00079 19.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_60s PF00428.19 CDJ60164.1 - 2.4 8.8 9.0 5.2 7.7 9.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.22 CDJ60165.1 - 1.1 8.4 28.4 1.2 8.3 28.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDRGK PF09756.9 CDJ60165.1 - 6.5 6.3 29.9 9.2 5.8 29.9 1.3 1 0 0 1 1 1 0 DDRGK domain SUIM_assoc PF16619.5 CDJ60166.1 - 0.66 10.1 10.8 1 9.4 4.4 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Myosin_head PF00063.21 CDJ60167.1 - 3.1e-33 115.0 0.1 6.6e-18 64.3 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) PAP1 PF08601.10 CDJ60167.1 - 0.18 11.5 4.1 0.23 11.2 4.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 CDJ60167.1 - 0.24 11.0 4.2 0.34 10.5 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med3 PF11593.8 CDJ60167.1 - 6.1 5.9 16.1 12 4.9 16.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3273 PF11677.8 CDJ60169.1 - 2.6e-63 213.8 11.4 3e-63 213.6 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Ras PF00071.22 CDJ60170.1 - 1.8e-54 183.7 0.1 1.8e-54 183.7 0.1 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDJ60170.1 - 8.9e-36 122.7 0.1 8.9e-36 122.7 0.1 3.0 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ60170.1 - 1e-13 51.1 0.1 1e-13 51.1 0.1 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ60170.1 - 3.9e-06 26.9 3.9 0.0028 17.7 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase SRPRB PF09439.10 CDJ60170.1 - 7.1e-06 25.6 2.3 0.0023 17.4 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDJ60170.1 - 0.0065 15.9 0.0 0.0065 15.9 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDJ60170.1 - 0.081 12.5 9.6 0.84 9.1 9.6 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.15 CDJ60170.1 - 0.82 9.2 27.6 1.3 8.6 27.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ60170.1 - 0.92 7.7 31.5 1.3 7.2 31.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 T2SSF PF00482.23 CDJ60170.1 - 7.6 6.5 11.8 9.4 6.2 10.8 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F IZUMO PF15005.6 CDJ60170.1 - 7.8 7.0 20.1 15 6.1 20.1 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Myb_DNA-binding PF00249.31 CDJ60171.1 - 4.1e-11 42.9 0.0 7.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CDJ60171.1 - 6.5e-09 35.6 8.1 6.5e-09 35.6 8.1 3.9 5 0 0 5 5 5 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CDJ60171.1 - 5.2e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 CDJ60171.1 - 0.013 15.6 2.2 0.013 15.6 2.2 5.4 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Fungal_trans_2 PF11951.8 CDJ60171.1 - 0.11 11.3 1.3 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Myb_DNA-bind_4 PF13837.6 CDJ60171.1 - 0.11 12.9 0.4 3 8.3 0.0 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SWIRM PF04433.17 CDJ60171.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 SWIRM domain Hamartin PF04388.12 CDJ60172.1 - 0.78 8.3 59.1 0.92 8.1 59.1 1.0 1 0 0 1 1 1 0 Hamartin protein Mpp10 PF04006.12 CDJ60173.1 - 0.005 15.3 32.4 0.005 15.3 32.4 2.3 2 0 0 2 2 2 1 Mpp10 protein Peptidase_S64 PF08192.11 CDJ60173.1 - 0.11 11.0 26.1 0.17 10.4 26.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.12 CDJ60173.1 - 0.33 9.1 55.5 0.035 12.3 44.3 2.0 2 0 0 2 2 2 0 Nop14-like family DUF572 PF04502.13 CDJ60173.1 - 5.3 6.6 37.3 7.7 6.0 37.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) YL1 PF05764.13 CDJ60173.1 - 9.1 6.3 60.6 0.03 14.4 47.0 2.3 1 1 1 2 2 2 0 YL1 nuclear protein TFIIA PF03153.13 CDJ60174.1 - 7.4e-05 22.9 24.5 7.4e-05 22.9 24.5 3.4 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit ANAPC_CDC26 PF10471.9 CDJ60174.1 - 0.0041 17.9 0.3 0.0041 17.9 0.3 8.1 6 3 1 7 7 7 1 Anaphase-promoting complex APC subunit CDC26 RskA PF10099.9 CDJ60174.1 - 0.013 15.8 3.1 0.013 15.8 3.1 6.8 4 3 1 5 5 5 0 Anti-sigma-K factor rskA PRIMA1 PF16101.5 CDJ60174.1 - 2.5 8.2 9.2 8.5 6.4 9.2 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Macoilin PF09726.9 CDJ60174.1 - 4.6 5.7 49.7 0.4 9.2 28.9 3.9 3 0 0 3 3 3 0 Macoilin family Caldesmon PF02029.15 CDJ60174.1 - 8.5 5.0 53.0 0.028 13.2 2.6 3.3 3 0 0 3 3 3 0 Caldesmon Spatacsin_C PF14649.6 CDJ60175.1 - 4.9e-13 48.8 2.0 0.00015 21.0 2.3 3.6 3 0 0 3 3 3 3 Spatacsin C-terminus Peptidase_M48_N PF16491.5 CDJ60176.1 - 5.1e-53 179.7 0.4 1.2e-52 178.5 0.4 1.6 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDJ60176.1 - 4e-38 131.2 0.0 6.9e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Ras PF00071.22 CDJ60178.1 - 0.002 17.7 0.0 0.003 17.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Arf PF00025.21 CDJ60178.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 CDJ60178.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SCP2 PF02036.17 CDJ60178.1 - 0.079 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family Hydrolase_4 PF12146.8 CDJ60179.1 - 2.1e-14 53.4 0.0 3.6e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ60179.1 - 1.1e-10 41.6 0.0 7.5e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDJ60179.1 - 6.4e-07 29.1 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CDJ60179.1 - 1.1e-06 27.5 0.3 0.0044 15.8 0.1 3.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 CDJ60179.1 - 1.1e-05 26.2 0.0 3.6e-05 24.5 0.0 1.8 1 1 2 3 3 3 1 Alpha/beta hydrolase family FSH1 PF03959.13 CDJ60179.1 - 3.1e-05 23.7 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 CDJ60179.1 - 3.5e-05 23.5 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 CDJ60179.1 - 0.00013 21.6 0.0 0.00053 19.6 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDJ60179.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDJ60179.1 - 0.0013 18.6 0.0 0.0082 16.0 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CDJ60179.1 - 0.013 15.4 0.0 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 CDJ60179.1 - 0.036 13.0 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 CDJ60179.1 - 0.16 11.7 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family LRR_6 PF13516.6 CDJ60180.1 - 0.075 13.1 0.3 46 4.4 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat CENP-B_dimeris PF09026.10 CDJ60180.1 - 3.2 8.2 6.7 7.8 6.9 6.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UPF1_Zn_bind PF09416.10 CDJ60184.1 - 6e-19 68.5 0.2 6.8e-19 68.3 0.2 1.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Nup214_FG PF18617.1 CDJ60185.1 - 0.056 14.0 4.0 19 5.9 1.4 3.4 2 1 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain NUP50 PF08911.11 CDJ60185.1 - 6.3 7.5 5.9 46 4.8 0.1 3.3 2 1 1 3 3 3 0 NUP50 (Nucleoporin 50 kDa) AAA_lid_11 PF18198.1 CDJ60186.1 - 7.7e-38 129.9 0.1 8.9e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Peptidase_S24 PF00717.23 CDJ60187.1 - 3.8e-08 33.1 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Bclt PF15318.6 CDJ60188.1 - 0.019 14.8 0.1 0.11 12.3 0.1 2.3 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis CS PF04969.16 CDJ60189.1 - 1.1e-14 55.1 0.0 2.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CDJ60189.1 - 6.8e-12 45.2 0.3 1.4e-11 44.2 0.3 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. WASH-7_C PF14746.6 CDJ60189.1 - 0.0055 16.4 6.4 0.0055 16.4 6.4 1.8 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal LCD1 PF09798.9 CDJ60189.1 - 0.065 11.8 7.2 0.079 11.5 7.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Spt20 PF12090.8 CDJ60189.1 - 0.69 9.5 22.3 0.02 14.5 13.7 2.0 2 0 0 2 2 2 0 Spt20 family Caudo_TAP PF02413.17 CDJ60189.1 - 0.77 9.9 12.7 0.56 10.4 8.5 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Activator_LAG-3 PF11498.8 CDJ60189.1 - 0.84 8.5 20.8 1.7 7.5 15.6 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MMR1 PF08505.10 CDJ60189.1 - 1 9.6 16.4 0.2 11.9 10.5 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Plasmodium_Vir PF05795.11 CDJ60189.1 - 1.4 8.3 8.2 0.17 11.3 3.7 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF1943 PF09172.11 CDJ60189.1 - 1.5 7.9 6.8 0.16 11.2 2.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) SLC12 PF03522.15 CDJ60189.1 - 2.1 7.3 14.1 0.15 11.0 6.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 YABBY PF04690.13 CDJ60189.1 - 3.8 8.1 7.5 1.9 9.0 3.7 2.1 2 0 0 2 2 2 0 YABBY protein Neur_chan_memb PF02932.16 CDJ60189.1 - 8.6 6.3 9.6 1.8 8.5 5.2 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PikAIV_N PF18605.1 CDJ60190.1 - 0.099 12.2 15.9 0.034 13.7 4.5 4.1 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF1018 PF06252.12 CDJ60190.1 - 0.44 11.6 5.5 1.1 10.3 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Leu_zip PF15294.6 CDJ60190.1 - 1.9 8.0 18.1 0.53 9.8 13.3 2.4 2 1 0 2 2 2 0 Leucine zipper DUF4746 PF15928.5 CDJ60191.1 - 0.27 10.6 12.7 0.15 11.4 6.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Myosin_head PF00063.21 CDJ60193.1 - 1.4e-73 248.3 0.1 1.9e-73 247.9 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Peptidase_M41 PF01434.18 CDJ60194.1 - 8.9e-48 162.7 0.0 8.9e-48 162.7 0.0 2.7 2 1 0 2 2 2 1 Peptidase family M41 AAA_lid_3 PF17862.1 CDJ60194.1 - 4.3e-12 45.6 0.1 1.6e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDJ60194.1 - 1.8e-07 31.6 0.0 1.8e-07 31.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF4719 PF15843.5 CDJ60194.1 - 0.54 10.3 2.3 1.6 8.8 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) CBM_25 PF03423.13 CDJ60194.1 - 1.7 8.9 8.7 0.15 12.3 0.7 2.5 3 0 0 3 3 3 0 Carbohydrate binding domain (family 25) Lin-8 PF03353.15 CDJ60194.1 - 3.3 7.2 58.7 2.6 7.5 2.6 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 CDJ60194.1 - 5.1 7.0 73.6 8.1 6.3 65.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Coilin_N PF15862.5 CDJ60199.1 - 0.0039 17.0 2.9 0.0039 17.0 2.9 10.7 8 2 3 11 11 11 1 Coilin N-terminus LETM1 PF07766.13 CDJ60200.1 - 1.5e-45 155.7 4.4 1.5e-45 155.7 4.4 2.8 3 1 0 3 3 3 1 LETM1-like protein RAP1 PF07218.11 CDJ60200.1 - 9.5 4.4 5.8 14 3.8 5.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PITH PF06201.13 CDJ60202.1 - 9.7e-17 61.6 0.0 1.8e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 PITH domain Mucin PF01456.17 CDJ60202.1 - 0.13 12.3 11.6 0.19 11.7 11.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SOG2 PF10428.9 CDJ60202.1 - 1.6 7.8 7.0 2.1 7.4 7.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DnaJ PF00226.31 CDJ60204.1 - 1.3e-08 34.8 0.0 2.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain AAA_9 PF12781.7 CDJ60206.1 - 7.1e-31 107.0 0.1 8.8e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Myosin_head PF00063.21 CDJ60207.1 - 5.7e-94 315.7 0.0 7.6e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CDJ60207.1 - 0.015 15.6 0.5 0.058 13.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDJ60207.1 - 0.039 13.2 0.1 0.096 11.9 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin PAP2 PF01569.21 CDJ60211.1 - 1.3e-22 80.0 3.7 1.3e-22 80.0 3.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CDJ60211.1 - 0.0021 18.5 1.0 0.0021 18.5 1.0 2.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal zf-RING_UBOX PF13445.6 CDJ60211.1 - 0.071 13.1 0.6 0.17 11.9 0.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DpnI PF06044.12 CDJ60211.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Dam-replacing family DUF2157 PF09925.9 CDJ60211.1 - 0.6 9.9 5.6 9.9 5.9 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Band_7 PF01145.25 CDJ60212.1 - 1.3e-27 96.9 0.9 2.5e-27 96.0 0.3 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CDJ60212.1 - 0.00037 19.7 2.3 0.00047 19.3 2.3 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CDJ60212.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family WHAMM-JMY_N PF15920.5 CDJ60212.1 - 0.068 13.0 0.5 0.17 11.8 0.5 1.6 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated DUF4290 PF14123.6 CDJ60212.1 - 0.093 12.3 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) Mannitol_dh PF01232.23 CDJ60212.1 - 0.15 12.2 1.1 0.27 11.4 1.1 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Dymeclin PF09742.9 CDJ60214.1 - 3.3e-14 52.2 0.6 2.8e-06 26.1 0.0 2.0 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CDJ60214.1 - 2.8e-13 48.9 0.9 3.5e-06 25.5 0.8 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein DAO PF01266.24 CDJ60215.1 - 1.8e-13 50.8 0.1 1.9e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDJ60215.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain Metallophos PF00149.28 CDJ60216.1 - 8.2e-12 46.0 0.2 1.8e-11 45.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HD_6 PF18019.1 CDJ60216.1 - 4.7 7.3 6.3 0.74 9.9 0.2 2.8 2 0 0 2 2 2 0 HD domain Adaptin_binding PF10199.9 CDJ60217.1 - 0.49 11.0 16.7 3.2 8.4 8.3 3.1 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Neur_chan_memb PF02932.16 CDJ60217.1 - 2.7 8.0 10.6 1.7 8.6 0.8 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.15 CDJ60217.1 - 9.6 6.8 8.9 6.9 7.3 0.5 2.9 3 0 0 3 3 3 0 Ctr copper transporter family Cpn60_TCP1 PF00118.24 CDJ60218.1 - 5.2e-128 427.8 2.3 8.8e-128 427.0 2.3 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TB2_DP1_HVA22 PF03134.19 CDJ60219.1 - 1.4e-14 53.7 2.6 2.3e-14 53.1 2.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SURF1 PF02104.15 CDJ60220.1 - 1.1e-25 90.9 0.1 1.4e-15 58.0 0.0 2.6 2 1 0 2 2 2 2 SURF1 family Cadherin_C_2 PF16492.5 CDJ60221.1 - 0.01 16.6 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Neurokinin_B PF03823.14 CDJ60221.1 - 0.012 15.6 1.4 1.2 9.2 0.1 2.8 2 0 0 2 2 2 0 Neurokinin B Chordopox_A33R PF05966.12 CDJ60221.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein NVEALA PF14055.6 CDJ60221.1 - 0.19 11.8 0.2 0.39 10.7 0.2 1.5 1 0 0 1 1 1 0 NVEALA protein RIC1 PF07064.13 CDJ60222.1 - 1.3e-08 34.6 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RIC1 DUF2083 PF09856.9 CDJ60222.1 - 0.04 13.8 1.7 0.12 12.2 1.7 1.7 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) ThiF PF00899.21 CDJ60223.1 - 2.9e-54 184.0 0.0 4.4e-31 108.1 0.0 4.8 4 1 0 4 4 4 4 ThiF family Shikimate_DH PF01488.20 CDJ60223.1 - 0.0017 18.4 0.2 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 CDJ60223.1 - 0.0085 16.0 2.4 4.8 7.0 0.2 3.6 4 0 0 4 4 4 1 Ubiquitin-activating enzyme active site 2-Hacid_dh_C PF02826.19 CDJ60223.1 - 0.013 14.9 0.0 1 8.7 0.0 2.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain E1_UFD PF09358.10 CDJ60223.1 - 0.025 15.2 0.0 0.064 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold domain Pyr_redox PF00070.27 CDJ60223.1 - 0.17 12.5 0.9 22 5.7 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KfrA_N PF11740.8 CDJ60224.1 - 0.024 15.3 2.8 0.024 15.3 2.8 3.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Erythro_esteras PF05139.14 CDJ60224.1 - 0.027 14.3 5.3 0.051 13.4 5.3 1.4 1 0 0 1 1 1 0 Erythromycin esterase KASH_CCD PF14662.6 CDJ60224.1 - 0.06 13.2 4.8 0.16 11.8 4.8 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 CDJ60224.1 - 0.06 13.5 0.7 0.77 9.9 0.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ferritin PF00210.24 CDJ60224.1 - 0.097 12.6 3.1 0.2 11.6 3.1 1.5 1 0 0 1 1 1 0 Ferritin-like domain NPV_P10 PF05531.12 CDJ60224.1 - 0.25 11.8 7.7 26 5.4 3.9 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoLp-III PF07464.11 CDJ60224.1 - 0.48 10.5 5.3 0.31 11.1 3.0 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 CDJ60224.1 - 0.54 10.3 3.9 1.9 8.5 3.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 CDJ60224.1 - 0.56 10.2 7.0 5.7 7.0 0.1 4.3 4 0 0 4 4 4 0 Short coiled-coil protein DUF4795 PF16043.5 CDJ60224.1 - 0.62 9.6 6.9 0.79 9.3 5.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 CDJ60224.1 - 0.87 8.4 7.2 1.6 7.6 7.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 CDJ60224.1 - 0.94 8.7 6.7 0.18 11.1 3.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PIN_8 PF18476.1 CDJ60224.1 - 1.5 8.7 5.3 6.6 6.5 1.7 2.5 2 1 0 2 2 2 0 PIN like domain DUF883 PF05957.13 CDJ60224.1 - 2.3 8.9 9.8 1.4 9.5 5.7 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 CDJ60224.1 - 2.6 7.3 10.2 5.6 6.2 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 CDJ60224.1 - 3 7.7 18.8 4 7.3 16.3 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 CDJ60224.1 - 3.3 8.0 5.3 5.5 7.3 1.8 3.2 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_S30 PF04758.14 CDJ60226.1 - 4.9e-25 87.5 10.3 7.1e-25 87.0 10.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 PhoLip_ATPase_N PF16209.5 CDJ60226.1 - 0.11 12.2 1.8 0.19 11.4 1.8 1.3 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal SOGA PF11365.8 CDJ60229.1 - 1.2 10.3 9.0 0.11 13.6 0.9 3.3 2 0 0 2 2 2 0 Protein SOGA Rft-1 PF04506.13 CDJ60230.1 - 3.6e-26 92.0 2.1 1.1e-16 60.7 0.1 2.2 2 0 0 2 2 2 2 Rft protein SET PF00856.28 CDJ60233.1 - 0.0066 16.9 0.0 0.0066 16.9 0.0 4.3 5 1 0 5 5 5 1 SET domain Pkinase PF00069.25 CDJ60234.1 - 4.8e-35 121.2 0.0 1.2e-22 80.5 0.0 6.4 4 2 2 7 7 7 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60234.1 - 1.8e-16 60.2 0.0 4.8e-15 55.5 0.0 4.8 4 1 1 5 5 5 2 Protein tyrosine kinase Spt20 PF12090.8 CDJ60235.1 - 0.0049 16.5 18.6 0.0049 16.5 18.6 8.0 6 2 0 6 6 6 3 Spt20 family Ribosomal_60s PF00428.19 CDJ60235.1 - 0.0061 17.1 11.2 0.0061 17.1 11.2 11.8 8 4 2 10 10 10 1 60s Acidic ribosomal protein RskA PF10099.9 CDJ60235.1 - 0.007 16.7 17.8 0.007 16.7 17.8 9.5 1 1 4 6 6 6 1 Anti-sigma-K factor rskA MecA PF05389.12 CDJ60235.1 - 0.0078 15.9 1.6 0.0078 15.9 1.6 6.3 6 1 0 6 6 6 2 Negative regulator of genetic competence (MecA) FAM176 PF14851.6 CDJ60235.1 - 0.011 15.4 1.9 0.011 15.4 1.9 6.8 6 2 1 7 7 7 0 FAM176 family DUF5523 PF17661.1 CDJ60235.1 - 8.5 6.0 68.4 1.2 8.8 6.7 5.3 5 0 0 5 5 5 0 Family of unknown function (DUF5523) PDZ_3 PF17815.1 CDJ60236.1 - 2e-17 63.4 0.4 2.2e-17 63.3 0.4 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDJ60236.1 - 0.0025 17.6 1.5 0.0025 17.6 0.1 1.8 3 0 0 3 3 3 1 PDZ domain RuBisCo_chap_C PF18087.1 CDJ60236.1 - 0.064 12.9 0.2 0.072 12.7 0.2 1.1 1 0 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain Tricorn_PDZ PF14685.6 CDJ60236.1 - 0.086 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain TMEM171 PF15471.6 CDJ60237.1 - 0.04 12.9 1.0 0.056 12.4 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Nas2_N PF18265.1 CDJ60238.1 - 3e-25 88.0 0.1 4.3e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CDJ60238.1 - 0.00037 20.3 0.1 0.00037 20.3 0.1 2.3 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 CDJ60238.1 - 0.02 15.2 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain NPV_P10 PF05531.12 CDJ60239.1 - 5.7 7.5 18.6 0.66 10.5 2.0 5.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Ribophorin_I PF04597.14 CDJ60240.1 - 1.4e-64 218.9 0.0 2e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 Ribophorin I DUF3327 PF11806.8 CDJ60240.1 - 0.11 13.3 0.5 0.34 11.6 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) SET PF00856.28 CDJ60241.1 - 1.6e-07 31.9 0.4 7.6e-06 26.4 0.0 2.5 3 0 0 3 3 3 2 SET domain Clathrin PF00637.20 CDJ60244.1 - 1.2e-171 563.4 20.5 1.6e-29 102.6 0.7 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CDJ60244.1 - 1.2e-27 95.6 0.1 1.1e-26 92.6 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 CDJ60244.1 - 2.6e-09 36.9 0.0 1e-05 25.6 0.0 4.4 4 0 0 4 4 4 1 Clathrin propeller repeat Coatomer_WDAD PF04053.14 CDJ60244.1 - 1.7e-07 30.7 0.6 0.32 10.0 0.0 3.8 3 0 0 3 3 3 3 Coatomer WD associated region TPR_19 PF14559.6 CDJ60244.1 - 0.059 13.9 9.9 0.63 10.6 0.2 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ60244.1 - 0.1 13.0 0.1 16 6.1 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60244.1 - 0.38 10.7 9.8 29 4.7 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60244.1 - 0.52 10.7 6.2 56 4.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ60244.1 - 1.2 8.9 4.8 8.6 6.1 0.2 4.0 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 CDJ60244.1 - 1.8 8.8 0.0 1.8 8.8 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ60244.1 - 4.1 8.1 15.4 2.9 8.6 0.1 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2457 PF10446.9 CDJ60245.1 - 0.015 14.5 35.4 0.043 13.0 35.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_tranf_2_3 PF13641.6 CDJ60245.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Nop14 PF04147.12 CDJ60245.1 - 0.42 8.8 25.8 0.96 7.6 25.8 1.5 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 CDJ60245.1 - 1.3 7.3 19.1 2.8 6.3 19.1 1.4 1 0 0 1 1 1 0 Mpp10 protein DUF4573 PF15140.6 CDJ60245.1 - 3.5 7.4 30.8 0.019 14.8 4.0 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4573) Sugar_tr PF00083.24 CDJ60246.1 - 7.1e-86 288.8 23.4 8.6e-86 288.6 23.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDJ60246.1 - 5.9e-29 101.1 30.8 8.1e-16 57.9 9.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDJ60246.1 - 0.066 11.5 10.2 0.014 13.8 4.5 2.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Holin_SPP1 PF04688.13 CDJ60246.1 - 4.1 7.6 7.2 8.1 6.7 1.2 3.2 2 0 0 2 2 2 0 SPP1 phage holin RRM_1 PF00076.22 CDJ60251.1 - 1.6e-09 37.4 0.0 5.1e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ60251.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.29 CDJ60252.1 - 1.2e-10 41.5 1.0 1.3e-06 28.3 0.2 5.6 6 2 0 6 6 6 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ60252.1 - 9.6e-06 25.9 0.0 9.6e-06 25.9 0.0 3.7 4 1 0 4 4 4 1 Helicase conserved C-terminal domain FAD_binding_2 PF00890.24 CDJ60253.1 - 2.6e-65 221.2 2.6 8.1e-62 209.6 1.1 5.3 4 2 2 6 6 4 2 FAD binding domain Succ_DH_flav_C PF02910.20 CDJ60253.1 - 3.1e-33 114.5 0.7 7.1e-33 113.3 0.7 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Spt20 PF12090.8 CDJ60253.1 - 0.0078 15.9 19.4 0.013 15.1 19.4 1.3 1 0 0 1 1 1 1 Spt20 family Lin-8 PF03353.15 CDJ60253.1 - 0.4 10.2 9.8 0.038 13.6 5.1 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 CDJ60253.1 - 0.52 9.3 4.3 0.41 9.6 2.8 1.5 2 0 0 2 2 2 0 Solute carrier family 12 Peptidase_S64 PF08192.11 CDJ60253.1 - 0.96 7.9 8.4 1.7 7.0 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 MAJIN PF15077.6 CDJ60253.1 - 1.3 8.8 3.5 2.5 7.8 3.5 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2722 PF10846.8 CDJ60253.1 - 1.3 7.8 21.9 0.06 12.3 15.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ60253.1 - 1.8 8.5 9.0 0.17 11.8 4.0 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 CDJ60253.1 - 3.2 6.6 22.6 5.5 5.8 22.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Plasmodium_Vir PF05795.11 CDJ60253.1 - 4.6 6.5 5.7 8.8 5.6 5.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 CDJ60253.1 - 5 8.2 7.3 16 6.5 7.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SWIRM-assoc_2 PF16496.5 CDJ60253.1 - 7.2 5.4 10.3 0.41 9.5 4.8 1.7 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal CAF1 PF04857.20 CDJ60255.1 - 0.066 12.4 10.7 0.52 9.4 6.6 2.4 2 1 0 2 2 2 0 CAF1 family ribonuclease BNR_3 PF13859.6 CDJ60255.1 - 1.3 8.2 8.5 7.2 5.8 5.6 2.4 2 0 0 2 2 2 0 BNR repeat-like domain AAA_11 PF13086.6 CDJ60255.1 - 1.4 8.7 22.3 13 5.5 0.2 2.6 2 1 0 2 2 2 0 AAA domain HMA PF00403.26 CDJ60256.1 - 3e-10 40.4 0.2 2.7e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CDJ60256.1 - 3.3e-05 23.5 16.4 0.079 12.5 0.0 4.8 4 1 1 5 5 5 3 E1-E2 ATPase UAA PF08449.11 CDJ60256.1 - 0.0021 17.3 0.2 0.65 9.2 0.0 2.5 2 0 0 2 2 2 2 UAA transporter family DUF2722 PF10846.8 CDJ60256.1 - 0.0034 16.4 11.1 0.0034 16.4 11.1 8.0 4 2 2 7 7 7 1 Protein of unknown function (DUF2722) PRCC PF10253.9 CDJ60257.1 - 4.5e-05 24.4 22.9 4.5e-05 24.4 22.9 3.3 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SUIM_assoc PF16619.5 CDJ60257.1 - 0.0095 16.0 10.5 0.0095 16.0 10.5 5.3 5 1 0 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 DUF3474 PF11960.8 CDJ60257.1 - 2.5 8.3 10.2 1.4 9.1 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) SPX PF03105.19 CDJ60257.1 - 5.6 6.8 51.2 0.31 10.9 17.3 2.3 2 0 0 2 2 2 0 SPX domain RskA PF10099.9 CDJ60257.1 - 9.4 6.5 46.4 0.045 14.0 4.2 3.2 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ60258.1 - 0.00058 18.9 8.5 0.00058 18.9 8.5 2.7 2 1 0 2 2 1 1 Protein of unknown function (DUF2722) MecA PF05389.12 CDJ60258.1 - 0.0039 16.9 7.7 0.028 14.0 0.7 2.5 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) DUF4834 PF16118.5 CDJ60258.1 - 0.0058 17.6 2.0 0.0058 17.6 2.0 3.8 2 1 1 3 3 2 1 Domain of unknown function (DUF4834) Jak1_Phl PF17887.1 CDJ60258.1 - 0.018 15.0 2.0 0.018 15.0 2.0 2.6 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Connexin PF00029.19 CDJ60258.1 - 0.071 12.9 9.9 0.63 9.8 1.8 2.3 2 0 0 2 2 2 0 Connexin Peroxin-13_N PF04088.13 CDJ60258.1 - 1.3 9.3 9.9 2.4 8.4 0.5 2.9 3 0 0 3 3 3 0 Peroxin 13, N-terminal region Tub PF01167.18 CDJ60258.1 - 2.4 7.8 9.2 4.2 7.1 3.5 2.2 2 0 0 2 2 2 0 Tub family Peptidase_S49_N PF08496.10 CDJ60258.1 - 2.9 8.0 21.2 0.58 10.2 6.4 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal V_ATPase_I PF01496.19 CDJ60258.1 - 3 5.6 13.6 2.2 6.1 3.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CDJ60258.1 - 4.1 6.2 8.0 8.5 5.2 0.7 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF1980 PF09323.10 CDJ60258.1 - 4.7 7.1 10.3 1.3 8.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Dpy19 PF10034.9 CDJ60258.1 - 7.7 4.6 6.1 3.5 5.7 3.0 1.7 2 0 0 2 2 2 0 Q-cell neuroblast polarisation PRC2_HTH_1 PF18118.1 CDJ60258.1 - 8.9 7.2 17.0 0.49 11.2 0.9 3.2 4 0 0 4 4 3 0 Polycomb repressive complex 2 tri-helical domain SR-25 PF10500.9 CDJ60259.1 - 0.075 12.6 19.5 0.1 12.2 19.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AMPKBI PF04739.15 CDJ60260.1 - 0.097 12.9 0.3 0.097 12.9 0.3 3.7 4 0 0 4 4 4 0 5'-AMP-activated protein kinase beta subunit, interaction domain LCCL PF03815.19 CDJ60261.1 - 9.6e-13 48.1 0.0 3e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.25 CDJ60261.1 - 1.3e-11 44.7 0.0 3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Ricin_B_lectin PF00652.22 CDJ60261.1 - 0.00099 19.4 0.5 0.0019 18.5 0.1 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Laminin_N PF00055.17 CDJ60261.1 - 0.0015 18.2 0.0 0.32 10.6 0.0 2.4 1 1 1 2 2 2 2 Laminin N-terminal (Domain VI) DUF1080 PF06439.11 CDJ60261.1 - 0.18 11.9 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Golgin_A5 PF09787.9 CDJ60261.1 - 2 7.8 6.1 2.8 7.3 0.3 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 CDJ60261.1 - 4.1 6.7 6.7 3.7 6.9 1.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RNA_pol_3_Rpc31 PF11705.8 CDJ60262.1 - 4.7e-08 33.6 11.2 4.7e-07 30.3 11.2 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 CDJ60262.1 - 0.0021 18.7 6.4 0.0044 17.7 6.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 CDJ60262.1 - 0.022 14.1 1.3 0.026 13.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) LRR19-TM PF15176.6 CDJ60262.1 - 5 7.2 5.9 9.6 6.3 5.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain AMP-binding PF00501.28 CDJ60264.1 - 1.7e-91 307.0 0.0 2.2e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDJ60264.1 - 3.8e-23 82.3 1.5 8e-23 81.2 1.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CDJ60264.1 - 1.1e-16 60.5 1.3 2.5e-16 59.3 1.3 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Cation_ATPase_C PF00689.21 CDJ60265.1 - 6.1e-35 120.6 0.5 6.1e-35 120.6 0.5 3.6 5 0 0 5 5 5 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDJ60265.1 - 1.5e-34 119.1 0.1 1.5e-34 119.1 0.1 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ60265.1 - 5.8e-17 62.7 1.1 1.7e-10 41.5 0.1 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDJ60265.1 - 3.2e-14 52.8 0.1 6e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDJ60265.1 - 6.6e-08 32.1 0.0 2.1e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDJ60265.1 - 0.00029 20.7 0.5 0.0018 18.1 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 CDJ60265.1 - 0.19 10.7 0.3 0.41 9.6 0.3 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain MMtag PF10159.9 CDJ60266.1 - 6.3e-18 64.8 2.4 6.3e-18 64.8 2.4 2.8 3 0 0 3 3 3 1 Multiple myeloma tumor-associated LCD1 PF09798.9 CDJ60266.1 - 5.4 5.4 10.3 5.5 5.4 10.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PIG-L PF02585.17 CDJ60266.1 - 9.7 6.8 7.0 2.3e+02 2.4 6.8 2.3 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase FUSC_2 PF13515.6 CDJ60267.1 - 2.6e-12 46.9 8.2 2.6e-12 46.9 8.2 3.5 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 CDJ60267.1 - 0.086 11.7 2.9 0.19 10.5 2.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.32 CDJ60269.1 - 0.0034 18.2 4.9 0.27 12.2 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Foie-gras_1 PF11817.8 CDJ60270.1 - 9e-07 28.7 0.2 9e-07 28.7 0.2 1.9 2 0 0 2 2 2 1 Foie gras liver health family 1 FeThRed_B PF02943.15 CDJ60270.1 - 0.042 13.8 0.7 0.1 12.6 0.7 1.6 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain STT3 PF02516.14 CDJ60271.1 - 2.4e-57 195.0 43.0 1.4e-44 152.8 25.7 3.4 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit BT1 PF03092.16 CDJ60272.1 - 1.1e-54 185.5 13.0 1.2e-27 96.4 2.2 2.2 2 0 0 2 2 2 2 BT1 family MFS_1 PF07690.16 CDJ60272.1 - 4.5e-13 48.8 35.5 9.3e-13 47.8 35.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 CDJ60272.1 - 0.0044 16.1 0.4 0.0044 16.1 0.4 2.1 2 1 0 2 2 2 1 PUCC protein DUF5418 PF17439.2 CDJ60272.1 - 0.033 14.3 1.5 0.084 12.9 1.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5418) Mt_ATP-synt_B PF05405.14 CDJ60272.1 - 0.049 13.3 2.1 0.1 12.2 2.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CitMHS PF03600.16 CDJ60272.1 - 0.075 12.2 12.2 0.5 9.5 11.7 2.0 1 1 0 1 1 1 0 Citrate transporter zf-CDGSH PF09360.10 CDJ60273.1 - 1.4e-08 34.8 1.1 1.4e-08 34.8 1.1 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Pyr_redox PF00070.27 CDJ60274.1 - 0.024 15.2 0.0 0.099 13.2 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc7 PF08317.11 CDJ60275.1 - 0.0052 15.7 6.3 0.0052 15.7 6.3 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Laminin_I PF06008.14 CDJ60275.1 - 0.012 15.3 12.3 0.11 12.2 7.6 2.1 2 0 0 2 2 2 0 Laminin Domain I Tropomyosin_1 PF12718.7 CDJ60275.1 - 0.017 15.3 7.7 0.017 15.3 7.7 2.0 2 0 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 CDJ60275.1 - 0.024 15.2 7.6 0.024 15.2 7.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region RUN PF02759.19 CDJ60275.1 - 0.038 13.9 1.1 0.068 13.1 0.8 1.7 1 1 0 1 1 1 0 RUN domain PAH PF02671.21 CDJ60275.1 - 0.12 12.6 1.4 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Jnk-SapK_ap_N PF09744.9 CDJ60275.1 - 0.29 11.4 13.5 0.25 11.6 7.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 CDJ60275.1 - 0.36 10.9 13.2 0.81 9.8 8.4 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 CDJ60275.1 - 0.66 10.3 6.6 2.6 8.3 5.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Trimer_CC PF08954.11 CDJ60275.1 - 0.96 9.1 8.5 0.29 10.7 4.3 2.2 1 1 1 2 2 2 0 Trimerisation motif Sec34 PF04136.15 CDJ60275.1 - 1.9 8.4 9.9 0.53 10.2 7.0 1.5 2 0 0 2 2 2 0 Sec34-like family TMF_DNA_bd PF12329.8 CDJ60275.1 - 3.4 7.7 14.0 19 5.4 9.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 CDJ60275.1 - 4.3 7.3 13.1 4.2 7.3 5.9 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 CDJ60275.1 - 4.3 8.3 13.1 2.6 9.0 8.2 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 CDJ60275.1 - 6.3 6.1 11.4 2.9 7.2 8.3 1.8 2 0 0 2 2 2 0 FAM76 protein ADIP PF11559.8 CDJ60275.1 - 7.6 6.6 16.1 8.9 6.4 11.3 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 CDJ60276.1 - 0.00045 19.9 3.0 0.00069 19.3 3.0 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF948 PF06103.11 CDJ60276.1 - 0.011 16.0 1.8 0.017 15.4 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Flg_hook PF02120.16 CDJ60276.1 - 0.011 15.6 1.8 0.062 13.2 0.0 2.9 2 1 0 2 2 2 0 Flagellar hook-length control protein FliK Macoilin PF09726.9 CDJ60276.1 - 0.012 14.2 2.0 0.014 14.0 2.0 1.2 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 CDJ60276.1 - 0.025 14.8 5.0 2.1 8.5 4.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Alpha-E PF04168.12 CDJ60276.1 - 0.051 13.4 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. vMSA PF00695.19 CDJ60276.1 - 0.17 10.9 0.9 0.26 10.4 0.9 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Prominin PF05478.11 CDJ60276.1 - 0.3 9.0 3.4 0.4 8.6 3.4 1.1 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 CDJ60276.1 - 0.47 9.5 8.2 0.11 11.5 4.8 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Plasmid_parti PF01672.16 CDJ60276.1 - 0.93 10.2 3.3 3.2 8.4 2.4 2.2 2 0 0 2 2 2 0 Putative plasmid partition protein FapA PF03961.13 CDJ60276.1 - 1.2 7.6 7.8 0.52 8.9 4.6 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A RskA PF10099.9 CDJ60278.1 - 7.6e-05 23.1 0.1 7.6e-05 23.1 0.1 13.8 4 4 6 10 10 10 2 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ60278.1 - 0.00014 21.6 14.0 0.00014 21.6 14.0 11.2 8 3 2 10 10 10 5 Nuclear RNA-splicing-associated protein TRM13 PF05206.14 CDJ60278.1 - 0.0004 20.0 2.8 0.0004 20.0 2.8 8.1 7 3 0 7 7 7 1 Methyltransferase TRM13 PAP_assoc PF03828.19 CDJ60278.1 - 0.0047 17.1 0.2 0.0047 17.1 0.2 2.6 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF4603 PF15376.6 CDJ60279.1 - 0.00047 17.7 15.5 0.00061 17.3 15.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) TCP PF03634.13 CDJ60279.1 - 0.17 12.4 27.3 3 8.4 21.0 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF572 PF04502.13 CDJ60279.1 - 0.21 11.2 24.7 0.29 10.7 24.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 CDJ60279.1 - 0.64 9.9 31.5 0.92 9.4 31.5 1.2 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 CDJ60279.1 - 0.86 7.6 39.4 1.3 7.0 39.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CCSAP PF15748.5 CDJ60279.1 - 2.1 8.4 32.5 0.55 10.4 19.8 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Utp14 PF04615.13 CDJ60279.1 - 2.5 6.5 27.0 3.4 6.1 27.0 1.0 1 0 0 1 1 1 0 Utp14 protein Peptidase_S64 PF08192.11 CDJ60279.1 - 5.2 5.4 33.6 6.4 5.1 33.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 CDJ60280.1 - 0.0084 15.7 3.5 0.0084 15.7 3.5 2.3 2 0 0 2 2 2 1 Spt20 family OATP PF03137.20 CDJ60280.1 - 0.068 11.4 1.3 3.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CCSAP PF15748.5 CDJ60280.1 - 0.12 12.6 17.0 0.3 11.2 7.6 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MAGE PF01454.19 CDJ60280.1 - 0.19 11.4 11.1 0.34 10.6 1.9 2.4 2 0 0 2 2 2 0 MAGE family SPX PF03105.19 CDJ60280.1 - 0.55 10.1 12.4 0.79 9.6 11.4 1.7 1 1 0 1 1 1 0 SPX domain TMEM208_SND2 PF05620.11 CDJ60280.1 - 0.98 9.2 5.4 4.9 6.9 5.4 2.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Jak1_Phl PF17887.1 CDJ60280.1 - 2.7 8.0 9.2 0.8 9.7 3.0 2.4 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Presenilin PF01080.17 CDJ60280.1 - 3 6.5 16.2 1.8 7.3 0.9 2.2 2 0 0 2 2 2 0 Presenilin Peptidase_S49_N PF08496.10 CDJ60280.1 - 4.4 7.4 9.4 0.18 11.9 2.2 2.4 2 1 0 2 2 2 0 Peptidase family S49 N-terminal Hid1 PF12722.7 CDJ60280.1 - 5.1 5.1 15.2 0.42 8.7 7.1 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PDDEXK_6 PF04720.12 CDJ60280.1 - 5.2 7.0 12.9 1.3 8.9 4.5 2.5 2 0 0 2 2 2 0 PDDEXK-like family of unknown function UPF0093 PF03653.13 CDJ60282.1 - 0.0053 17.0 0.2 0.008 16.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) DUF1967 PF09269.11 CDJ60283.1 - 0.045 13.7 0.1 0.82 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Cpn60_TCP1 PF00118.24 CDJ60285.1 - 1.6e-37 129.3 0.0 2.8e-37 128.5 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aminotran_1_2 PF00155.21 CDJ60286.1 - 1.8e-38 132.7 0.0 2.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 CDJ60286.1 - 0.00014 20.8 0.0 0.00055 18.8 0.0 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 CDJ60286.1 - 0.00039 19.1 0.0 0.00084 18.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDJ60286.1 - 0.00088 18.7 0.3 0.015 14.6 0.3 2.6 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDJ60286.1 - 0.057 12.7 0.1 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DUF2236 PF09995.9 CDJ60286.1 - 0.071 13.3 0.6 0.93 9.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) eIF3_subunit PF08597.10 CDJ60287.1 - 2.4 8.0 15.6 3.5 7.5 15.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Striatin PF08232.12 CDJ60287.1 - 3.1 8.4 6.9 4.4 7.9 6.9 1.2 1 0 0 1 1 1 0 Striatin family PUA_3 PF17785.1 CDJ60288.1 - 4.8e-13 48.7 0.0 9.5e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain zf-CCCH PF00642.24 CDJ60289.1 - 1.6e-08 34.2 22.9 1.9e-06 27.6 4.5 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDJ60289.1 - 3.2e-05 23.6 4.7 3.2e-05 23.6 4.7 3.8 4 0 0 4 4 4 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDJ60289.1 - 0.00018 21.4 6.6 0.00018 21.4 6.6 4.8 4 1 0 4 4 4 1 Zinc finger domain Torus PF16131.5 CDJ60289.1 - 0.00043 21.0 2.2 0.00043 21.0 2.2 4.4 2 1 2 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 CDJ60289.1 - 0.011 16.0 6.7 0.062 13.5 6.0 2.6 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDJ60289.1 - 2.1 9.0 8.5 20 5.8 0.1 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SUIM_assoc PF16619.5 CDJ60290.1 - 0.0026 17.8 5.1 0.02 14.9 5.1 2.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Orf78 PF06024.12 CDJ60290.1 - 0.48 10.7 3.7 1 9.7 0.3 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Roughex PF06020.11 CDJ60290.1 - 2 7.4 10.7 0.23 10.5 0.9 2.3 2 0 0 2 2 2 0 Drosophila roughex protein LZ_Tnp_IS66 PF13007.7 CDJ60291.1 - 1.5 9.7 6.4 2 9.2 0.5 2.3 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain E1-E2_ATPase PF00122.20 CDJ60292.1 - 1e-15 57.7 8.6 1.3e-08 34.6 3.2 2.9 2 1 1 3 3 3 2 E1-E2 ATPase HMA PF00403.26 CDJ60292.1 - 1.8e-09 37.9 0.3 4.8e-09 36.5 0.2 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase PF00702.26 CDJ60292.1 - 0.0078 16.5 0.0 0.12 12.7 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Virul_fac_BrkB PF03631.15 CDJ60293.1 - 9.7 5.7 18.8 0.12 11.9 1.2 4.1 4 1 0 4 4 4 0 Virulence factor BrkB DEAD PF00270.29 CDJ60294.1 - 6.5e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ60294.1 - 1.4e-19 70.5 0.0 4e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Abhydrolase_6 PF12697.7 CDJ60295.1 - 7.7e-17 62.6 0.5 2.6e-15 57.6 0.2 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDJ60295.1 - 5.1e-08 32.5 0.1 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ60295.1 - 2.2e-07 30.8 0.0 6.3e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ60295.1 - 0.00026 20.8 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CDJ60295.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CDJ60295.1 - 0.027 14.6 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 CDJ60295.1 - 0.032 14.1 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) MT PF12777.7 CDJ60296.1 - 2.9e-79 266.6 13.3 4.7e-79 265.9 13.3 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CDJ60296.1 - 1.5e-55 187.7 1.4 2.3e-53 180.6 0.0 2.8 1 1 1 2 2 2 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ60296.1 - 2e-48 164.3 0.0 3.5e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CDJ60296.1 - 1.9e-47 162.0 1.8 1.7e-44 152.3 0.1 3.1 2 1 1 3 3 3 2 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CDJ60296.1 - 1.7e-16 60.4 0.0 4.9e-06 26.6 0.0 3.9 2 1 1 3 3 3 2 Dynein heavy chain region D6 P-loop domain Spc7 PF08317.11 CDJ60296.1 - 1.3 7.8 21.7 0.034 13.0 1.0 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec34 PF04136.15 CDJ60296.1 - 4.3 7.2 8.7 14 5.6 0.3 3.3 3 0 0 3 3 3 0 Sec34-like family DUF3450 PF11932.8 CDJ60296.1 - 5.8 6.2 18.6 1.2 8.3 3.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 CDJ60296.1 - 7 6.7 19.9 0.041 13.9 1.7 4.6 4 1 1 5 5 5 0 Laminin Domain II DUF948 PF06103.11 CDJ60296.1 - 9.3 6.6 12.7 3.6 7.9 0.2 4.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 CDJ60297.1 - 4.6e-12 46.5 0.0 5.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ60297.1 - 6.3e-07 29.7 0.1 3.6e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ60297.1 - 8.6e-07 29.5 0.8 9.3e-06 26.1 0.8 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 CDJ60297.1 - 1.5e-06 28.3 0.1 1.1e-05 25.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ60297.1 - 4.8e-06 26.4 0.0 6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 CDJ60297.1 - 1.6e-05 24.7 0.0 0.0024 17.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 CDJ60297.1 - 0.00032 21.0 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDJ60297.1 - 0.00037 20.5 0.0 0.00049 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ60297.1 - 0.0006 19.9 0.0 0.0028 17.7 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDJ60297.1 - 0.00082 18.7 0.0 0.0024 17.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CDJ60297.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDJ60297.1 - 0.0012 18.8 0.0 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ60297.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CDJ60297.1 - 0.0034 16.9 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 CDJ60297.1 - 0.0074 16.1 0.1 0.36 10.6 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase NACHT PF05729.12 CDJ60297.1 - 0.0079 16.1 0.3 0.017 15.0 0.3 1.5 1 1 0 1 1 1 1 NACHT domain TniB PF05621.11 CDJ60297.1 - 0.008 15.6 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 CDJ60297.1 - 0.0085 15.5 0.1 0.038 13.4 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CDJ60297.1 - 0.02 14.4 0.0 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CDJ60297.1 - 0.028 14.6 0.1 0.033 14.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CDJ60297.1 - 0.033 13.9 0.0 0.046 13.4 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CDJ60297.1 - 0.05 12.8 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 CDJ60297.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDJ60297.1 - 0.059 13.2 0.1 0.23 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDJ60297.1 - 0.066 13.3 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_35 PF14516.6 CDJ60297.1 - 0.067 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 CDJ60297.1 - 0.072 13.3 0.2 0.1 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDJ60297.1 - 0.082 12.7 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain TIP49 PF06068.13 CDJ60297.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ60297.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 RNA helicase SbcCD_C PF13558.6 CDJ60297.1 - 0.13 12.5 0.3 0.36 11.1 0.1 1.7 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CDJ60297.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CDJ60297.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 CDJ60297.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ERCC4 PF02732.15 CDJ60299.1 - 3.3e-09 37.1 1.6 4.7e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 ERCC4 domain SR-25 PF10500.9 CDJ60299.1 - 0.003 17.2 2.8 0.003 17.2 2.8 11.9 9 3 2 11 11 11 4 Nuclear RNA-splicing-associated protein GCFC PF07842.12 CDJ60300.1 - 1e-20 74.5 21.0 1e-20 74.5 21.0 4.7 3 2 1 4 4 4 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CDJ60300.1 - 1.2e-08 34.7 1.4 3.7e-08 33.1 1.4 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 CDJ60300.1 - 0.00018 21.8 8.3 0.00018 21.8 8.3 8.1 5 2 3 8 8 8 1 Tuftelin interacting protein N terminal SUIM_assoc PF16619.5 CDJ60300.1 - 0.068 13.2 0.0 0.068 13.2 0.0 15.5 13 3 1 14 14 14 0 Unstructured region C-term to UIM in Ataxin3 TatD_DNase PF01026.21 CDJ60302.1 - 5.6e-34 117.7 0.0 1.9e-33 116.0 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Spt20 PF12090.8 CDJ60302.1 - 0.015 14.9 30.3 0.093 12.3 3.1 3.3 3 0 0 3 3 3 0 Spt20 family DUF1833 PF08875.11 CDJ60302.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) RskA PF10099.9 CDJ60302.1 - 2.2 8.6 39.8 0.066 13.5 7.6 3.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TSGP1 PF07771.11 CDJ60303.1 - 4.8 7.3 12.0 2.5 8.3 8.2 2.7 1 1 0 1 1 1 0 Tick salivary peptide group 1 DUF2722 PF10846.8 CDJ60306.1 - 0.0059 15.6 0.9 0.0059 15.6 0.9 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) HisKA_3 PF07730.13 CDJ60306.1 - 0.11 13.0 0.4 0.11 13.0 0.4 4.1 4 1 0 4 4 4 0 Histidine kinase Peptidase_S15 PF02129.18 CDJ60306.1 - 9.5 5.7 18.1 0.66 9.5 4.5 3.2 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) AAA_25 PF13481.6 CDJ60307.1 - 0.0056 16.3 0.4 0.38 10.3 0.2 2.7 2 0 0 2 2 2 1 AAA domain SMC_hinge PF06470.13 CDJ60307.1 - 0.05 13.9 1.3 0.86 9.9 0.0 3.0 2 1 0 2 2 2 0 SMC proteins Flexible Hinge Domain NACHT PF05729.12 CDJ60307.1 - 0.083 12.8 7.1 1.7 8.5 0.1 3.6 4 0 0 4 4 4 0 NACHT domain CENP-Q PF13094.6 CDJ60308.1 - 0.0084 16.3 16.3 0.0084 16.3 16.3 2.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit LUC7 PF03194.15 CDJ60309.1 - 5.9e-18 65.5 0.2 5.9e-18 65.5 0.2 2.3 2 0 0 2 2 2 1 LUC7 N_terminus V_ATPase_I PF01496.19 CDJ60309.1 - 0.89 7.4 4.7 1.4 6.8 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Endonuc_Holl PF10107.9 CDJ60309.1 - 1.3 8.8 5.4 3.1 7.6 5.4 1.6 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CLN3 PF02487.17 CDJ60309.1 - 6.4 5.7 4.7 12 4.8 4.7 1.4 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 CDJ60309.1 - 7.4 6.6 20.1 0.52 10.3 14.2 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Totivirus_coat PF05518.11 CDJ60310.1 - 1.9e-24 85.8 0.1 5e-18 64.6 0.0 2.0 2 0 0 2 2 2 2 Totivirus coat protein Pkinase PF00069.25 CDJ60313.1 - 6.8e-46 156.8 8.5 1.9e-32 112.7 0.0 3.9 4 0 0 4 4 4 2 Protein kinase domain LSM PF01423.22 CDJ60314.1 - 3.4e-09 36.3 0.0 6.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain Thiol_cytolysin PF01289.19 CDJ60314.1 - 0.12 11.3 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin RAP1 PF07218.11 CDJ60314.1 - 7.4 4.7 5.3 7.1 4.8 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Utp21 PF04192.12 CDJ60315.1 - 7.8 5.9 7.8 0.87 9.0 1.4 2.1 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CDJ60316.1 - 1.5e-08 34.8 0.1 0.029 14.7 0.0 4.9 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ60316.1 - 2.3e-05 25.1 15.4 4.2 8.4 0.0 6.0 7 0 0 7 7 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 CDJ60316.1 - 0.0072 16.3 0.0 7.5 6.6 0.0 4.1 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region AP3D1 PF06375.11 CDJ60316.1 - 0.017 15.3 7.0 0.017 15.3 7.0 1.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Hira PF07569.11 CDJ60316.1 - 0.04 13.7 1.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split GREB1 PF15782.5 CDJ60316.1 - 0.073 10.2 1.4 0.088 9.9 1.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Adaptin_binding PF10199.9 CDJ60316.1 - 0.11 13.1 7.4 1 10.0 8.8 1.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Rhabdo_ncap PF00945.18 CDJ60316.1 - 0.16 10.8 1.7 0.21 10.4 1.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein NARP1 PF12569.8 CDJ60316.1 - 0.92 8.3 9.8 1.5 7.6 9.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Androgen_recep PF02166.16 CDJ60316.1 - 1.3 7.8 7.2 2.5 6.8 7.2 1.4 1 0 0 1 1 1 0 Androgen receptor DUF4692 PF15763.5 CDJ60316.1 - 1.4 9.4 4.9 2.5 8.5 4.9 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Vfa1 PF08432.10 CDJ60316.1 - 1.5 9.1 14.1 0.17 12.2 9.8 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF755 PF05501.11 CDJ60316.1 - 2.1 8.7 20.6 0.031 14.6 12.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4746 PF15928.5 CDJ60316.1 - 2.7 7.3 7.0 4.1 6.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) U3_snoRNA_assoc PF08297.11 CDJ60316.1 - 2.8 8.7 12.8 25 5.7 7.5 2.4 2 0 0 2 2 2 0 U3 snoRNA associated zf-CW PF07496.15 CDJ60317.1 - 2.1e-15 56.4 4.9 2.1e-15 56.4 4.9 1.8 2 0 0 2 2 2 1 CW-type Zinc Finger IMUP PF15761.5 CDJ60318.1 - 0.089 13.5 10.3 0.2 12.3 10.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SDA1 PF05285.12 CDJ60318.1 - 0.32 10.4 52.1 0.37 10.2 52.1 1.1 1 0 0 1 1 1 0 SDA1 PRP38_assoc PF12871.7 CDJ60318.1 - 4.2 8.0 32.4 3.6 8.2 15.7 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFIIA PF03153.13 CDJ60322.1 - 0.38 10.7 28.4 0.055 13.5 19.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SHR-BD PF06650.12 CDJ60323.1 - 1.5e-05 24.5 0.0 4.6e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CDJ60323.1 - 0.00033 20.5 0.0 0.00083 19.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_L31e PF01198.19 CDJ60324.1 - 1e-39 134.6 2.7 1e-39 134.6 2.7 1.4 2 0 0 2 2 2 1 Ribosomal protein L31e Rep_fac_C PF08542.11 CDJ60325.1 - 2.6e-08 34.1 0.0 7.5e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CDJ60325.1 - 5e-05 23.7 0.0 0.0013 19.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDJ60325.1 - 0.0002 21.2 0.1 0.00034 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CDJ60325.1 - 0.00031 21.0 0.0 0.0007 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 CDJ60325.1 - 0.0035 17.6 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 CDJ60325.1 - 0.0041 16.9 0.1 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 CDJ60325.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ60325.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CDJ60325.1 - 0.069 13.1 0.2 7 6.5 0.0 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 CDJ60325.1 - 0.097 12.2 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 CDJ60325.1 - 0.15 12.0 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 CDJ60325.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Macoilin PF09726.9 CDJ60325.1 - 0.24 9.9 1.3 0.27 9.7 1.3 1.2 1 0 0 1 1 1 0 Macoilin family HA2 PF04408.23 CDJ60326.1 - 4.4e-23 81.6 0.2 1.7e-22 79.7 0.2 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDJ60326.1 - 9.8e-21 73.9 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDJ60326.1 - 6.5e-11 42.6 0.0 3.4e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ60326.1 - 2.4e-07 31.1 0.1 8.9e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDJ60326.1 - 1.6e-06 28.0 0.1 3.3e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDJ60326.1 - 2.9e-05 23.9 0.1 6.2e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ60326.1 - 3.9e-05 24.0 0.2 9.5e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDJ60326.1 - 0.0021 17.6 0.0 0.0055 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CDJ60326.1 - 0.0029 17.6 0.1 0.31 11.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 CDJ60326.1 - 0.0045 16.6 0.5 0.019 14.6 0.5 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CDJ60326.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 CDJ60326.1 - 0.011 15.9 0.2 0.063 13.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDJ60326.1 - 0.019 15.3 0.0 0.096 13.1 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CDJ60326.1 - 0.026 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 CDJ60326.1 - 0.03 13.9 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ60326.1 - 0.038 14.5 3.3 1.2 9.6 0.2 3.8 3 1 1 4 4 4 0 ABC transporter DAP3 PF10236.9 CDJ60326.1 - 0.07 12.3 0.2 0.17 11.0 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 CDJ60326.1 - 0.57 10.1 2.5 0.56 10.1 0.1 2.3 3 0 0 3 3 2 0 NACHT domain TrwB_AAD_bind PF10412.9 CDJ60326.1 - 3.5 6.4 5.9 0.24 10.3 0.3 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DPPIV_N PF00930.21 CDJ60327.1 - 9.9e-21 73.9 0.2 1.8e-13 50.0 0.0 4.2 5 0 0 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ribosomal_60s PF00428.19 CDJ60327.1 - 0.0075 16.8 0.7 0.0075 16.8 0.7 11.0 9 2 3 12 12 12 3 60s Acidic ribosomal protein DUF2828 PF11443.8 CDJ60327.1 - 0.16 10.0 15.2 0.78 7.8 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Otopetrin PF03189.13 CDJ60327.1 - 0.65 8.7 5.2 0.89 8.3 0.9 2.2 2 0 0 2 2 2 0 Otopetrin Peptidase_S9 PF00326.21 CDJ60328.1 - 1.6e-34 119.3 0.0 4.1e-33 114.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDJ60328.1 - 0.00033 20.4 0.9 0.09 12.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CDJ60328.1 - 0.0008 19.1 0.0 0.0019 17.9 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CDJ60328.1 - 0.069 12.4 0.5 0.73 9.1 0.2 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Myosin_head PF00063.21 CDJ60330.1 - 5.9e-187 622.9 0.1 7.1e-187 622.7 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CDJ60330.1 - 0.017 15.5 0.0 0.049 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CDJ60330.1 - 0.15 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ICMT PF04140.14 CDJ60332.1 - 1.2e-19 70.5 0.6 5.9e-19 68.3 0.2 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDJ60332.1 - 3.4e-07 30.6 0.1 1.1e-06 29.0 0.1 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CDJ60332.1 - 0.0023 17.5 0.4 0.0023 17.5 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) TetR_C_12 PF16914.5 CDJ60332.1 - 0.017 15.2 0.0 0.057 13.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal ERG4_ERG24 PF01222.17 CDJ60332.1 - 0.048 12.4 1.6 0.1 11.4 1.6 1.4 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1075 PF06388.11 CDJ60332.1 - 0.43 10.6 2.9 1 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) DUF3021 PF11457.8 CDJ60332.1 - 2.1 8.7 7.4 1.5 9.1 2.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3021) BaxI_1 PF12811.7 CDJ60333.1 - 0.0036 16.9 0.9 0.0036 16.9 0.9 1.5 2 0 0 2 2 2 1 Bax inhibitor 1 like DUF3611 PF12263.8 CDJ60333.1 - 0.57 10.1 6.2 3 7.7 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) UQ_con PF00179.26 CDJ60334.1 - 2.8e-44 150.2 0.0 3.4e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ60334.1 - 0.0033 17.1 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDJ60334.1 - 0.0063 16.4 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CDJ60334.1 - 0.16 12.3 0.2 0.26 11.6 0.2 1.3 1 1 0 1 1 1 0 RWD domain DUF4064 PF13273.6 CDJ60335.1 - 0.0015 18.8 5.4 0.041 14.2 0.4 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4064) Peptidase_U4 PF03419.13 CDJ60335.1 - 9.1 5.5 12.4 17 4.6 12.4 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Glyco_transf_90 PF05686.12 CDJ60336.1 - 4.7e-67 226.6 0.0 6.8e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.20 CDJ60336.1 - 6.7e-42 141.7 0.0 4.4e-22 78.0 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 CDJ60336.1 - 7.3e-11 42.5 0.0 0.00017 22.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDJ60336.1 - 1.3e-09 37.8 0.1 3.1e-06 26.8 0.0 3.2 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDJ60336.1 - 5.6e-08 32.9 0.0 0.0032 17.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.6 CDJ60336.1 - 8.5e-05 22.5 0.1 0.073 13.0 0.1 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDJ60336.1 - 0.0023 18.2 0.0 1.8 9.0 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like ERp29_N PF07912.13 CDJ60336.1 - 0.0037 17.4 0.1 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 ERp29, N-terminal domain Glyco_trans_1_2 PF13524.6 CDJ60336.1 - 0.0062 16.9 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TraF PF13728.6 CDJ60336.1 - 0.01 15.7 0.0 5 6.9 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 CDJ60336.1 - 0.013 15.5 0.0 7.1 6.6 0.0 2.9 2 0 0 2 2 2 0 AhpC/TSA family Glutaredoxin PF00462.24 CDJ60336.1 - 0.016 15.4 0.0 0.93 9.8 0.0 3.1 3 0 0 3 3 3 0 Glutaredoxin Thioredoxin_9 PF14595.6 CDJ60336.1 - 0.048 13.4 0.1 5 6.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 CDJ60336.1 - 0.092 12.4 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Redoxin EF-hand_1 PF00036.32 CDJ60338.1 - 1.4e-27 93.1 4.7 1.9e-07 30.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CDJ60338.1 - 4.7e-25 85.9 2.5 5.6e-07 28.8 0.3 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CDJ60338.1 - 6.9e-24 84.1 3.1 2.8e-12 46.9 0.5 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60338.1 - 7e-21 72.3 4.4 0.00084 19.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDJ60338.1 - 1.8e-12 46.9 8.8 3.7e-05 23.5 1.4 4.6 4 1 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ60338.1 - 1.5e-09 38.2 0.0 0.0003 21.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDJ60338.1 - 6.3e-05 22.9 2.3 0.15 12.0 0.4 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDJ60338.1 - 0.0002 21.5 3.7 0.0086 16.2 0.1 3.7 2 1 2 4 4 4 3 Dockerin type I domain EF-hand_9 PF14658.6 CDJ60338.1 - 0.00076 19.8 0.0 0.048 14.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain NOD2_WH PF17779.1 CDJ60338.1 - 0.031 14.6 0.1 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 NOD2 winged helix domain Caleosin PF05042.13 CDJ60338.1 - 0.059 13.3 1.3 4.6 7.2 0.0 3.2 2 1 2 4 4 4 0 Caleosin related protein BDV_P40 PF06407.11 CDJ60338.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Borna disease virus P40 protein PUB PF09409.10 CDJ60339.1 - 0.0024 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 PUB domain Mito_carr PF00153.27 CDJ60340.1 - 2.3e-31 107.6 1.5 2.8e-14 52.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO PF00650.20 CDJ60343.1 - 2.3e-26 92.4 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain IMCp PF12314.8 CDJ60344.1 - 7.3e-29 99.9 55.8 5.2e-26 90.8 39.4 2.0 1 1 1 2 2 2 2 Inner membrane complex protein RRM_1 PF00076.22 CDJ60345.1 - 2.9e-26 91.1 0.0 9.1e-16 57.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ60345.1 - 0.28 11.0 3.2 31 4.5 0.0 3.6 4 0 0 4 4 4 0 Occluded RNA-recognition motif CorA PF01544.18 CDJ60346.1 - 0.036 13.4 0.2 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein NAD_binding_1 PF00175.21 CDJ60348.1 - 1.5e-15 57.8 0.0 2.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pkinase PF00069.25 CDJ60349.1 - 4.3e-58 196.8 0.0 6.2e-57 193.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60349.1 - 5.4e-27 94.7 0.0 1.5e-18 67.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4064 PF13273.6 CDJ60352.1 - 0.0092 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Peptidase_C14 PF00656.22 CDJ60356.1 - 1.5e-27 97.2 0.0 2.9e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Caspase domain DUF384 PF04064.13 CDJ60357.1 - 6.8e-07 29.0 1.0 2.3e-06 27.4 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 CDJ60357.1 - 0.016 14.9 9.6 0.024 14.3 4.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF383) CoA_binding PF02629.19 CDJ60358.1 - 3.7e-21 75.6 0.0 1.3e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CDJ60358.1 - 1.4e-12 47.7 1.1 1.9e-09 37.5 0.3 2.2 1 1 1 2 2 2 2 CoA-ligase Succ_CoA_lig PF13607.6 CDJ60358.1 - 0.032 14.0 3.5 0.34 10.7 0.6 2.4 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Pga1 PF10333.9 CDJ60360.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Vps35 PF03635.17 CDJ60361.1 - 4.7e-132 442.0 0.2 5.6e-132 441.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 POB3_N PF17292.2 CDJ60363.1 - 3.1e-23 82.0 0.2 1.6e-22 79.8 0.1 2.2 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 CDJ60363.1 - 5.2e-21 74.3 0.6 2.2e-20 72.3 0.0 2.4 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 CDJ60363.1 - 3.2e-19 69.1 1.4 2.3e-17 63.2 0.2 3.6 3 1 0 3 3 3 1 Histone chaperone Rttp106-like YL1 PF05764.13 CDJ60363.1 - 0.00057 20.1 29.6 0.0012 19.0 29.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CCDC106 PF15794.5 CDJ60363.1 - 2 8.1 12.7 3.6 7.2 12.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop14 PF04147.12 CDJ60363.1 - 6.3 4.9 25.1 8.6 4.4 25.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 CDJ60365.1 - 9.1e-22 78.1 1.2 2e-21 77.0 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 AP2 PF00847.20 CDJ60366.1 - 9e-10 38.6 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.20 CDJ60367.1 - 2.3e-12 46.9 0.1 4.6e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 AP2 domain DAO_C PF16901.5 CDJ60368.1 - 9.6e-27 93.3 0.0 1.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DUF3131 PF11329.8 CDJ60368.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) ABC_tran PF00005.27 CDJ60369.1 - 2.2e-19 70.4 0.0 5.9e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDJ60369.1 - 4.1e-06 26.7 0.1 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SbcCD_C PF13558.6 CDJ60369.1 - 6.8e-06 26.2 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CDJ60369.1 - 8.2e-05 23.0 0.0 8.2e-05 23.0 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 CDJ60369.1 - 0.00013 21.5 0.1 0.048 13.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDJ60369.1 - 0.0045 17.3 0.0 0.31 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDJ60369.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CDJ60369.1 - 0.082 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CDJ60369.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UME PF08064.13 CDJ60372.1 - 0.039 13.9 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain TrmO_C PF18389.1 CDJ60373.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain RT_RNaseH_2 PF17919.1 CDJ60374.1 - 2.9e-30 104.2 0.2 4.2e-30 103.7 0.2 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ60374.1 - 2.5e-29 101.6 0.1 4.1e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 CDJ60376.1 - 4.1e-38 129.1 0.2 2.5e-16 59.2 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ60376.1 - 2.9e-07 30.5 0.1 0.089 12.9 0.0 4.1 3 0 0 3 3 3 3 RNA recognition motif WW PF00397.26 CDJ60376.1 - 3.9e-06 26.8 3.6 7.5e-06 25.9 3.6 1.4 1 0 0 1 1 1 1 WW domain Caldesmon PF02029.15 CDJ60376.1 - 0.0017 17.3 18.1 0.0017 17.3 18.1 2.1 2 0 0 2 2 2 2 Caldesmon RNA_bind PF08675.11 CDJ60376.1 - 0.071 13.2 0.2 1.8 8.6 0.0 2.9 3 1 0 3 3 3 0 RNA binding domain SUIM_assoc PF16619.5 CDJ60378.1 - 0.0041 17.2 15.5 4.5 7.4 6.4 4.8 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 RIC3 PF15361.6 CDJ60378.1 - 0.084 13.3 0.0 0.084 13.3 0.0 3.5 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2722 PF10846.8 CDJ60378.1 - 9.4 5.0 21.6 0.22 10.4 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Tubulin PF00091.25 CDJ60379.1 - 7.4e-16 58.9 0.0 1.5e-11 44.8 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sec1 PF00995.23 CDJ60380.1 - 9.1e-29 101.1 0.0 1e-28 100.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Helicase_C PF00271.31 CDJ60381.1 - 7.4e-19 68.1 0.0 1.3e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDJ60381.1 - 0.0042 16.3 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1652 PF07865.11 CDJ60381.1 - 0.14 12.0 0.3 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) UQ_con PF00179.26 CDJ60382.1 - 3.7e-45 153.0 0.0 4.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ60382.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CDJ60382.1 - 0.25 11.7 1.2 0.42 10.9 1.1 1.6 1 1 0 1 1 1 0 RWD domain GLTP PF08718.11 CDJ60384.1 - 1e-23 84.3 0.0 1.2e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) RRM_1 PF00076.22 CDJ60386.1 - 8.6e-15 54.3 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDJ60386.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Limkain b1 Phage_holin_3_1 PF05106.12 CDJ60388.1 - 1.9 9.0 5.7 6.6 7.2 0.3 2.8 1 1 1 3 3 3 0 Phage holin family (Lysis protein S) BRCT_3 PF18428.1 CDJ60390.1 - 3.2e-05 23.9 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain ASC PF00858.24 CDJ60390.1 - 0.0072 15.3 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel NEMP PF10225.9 CDJ60390.1 - 0.41 10.3 1.9 1.3 8.6 1.9 1.8 1 0 0 1 1 1 0 NEMP family Lin-8 PF03353.15 CDJ60390.1 - 6.1 6.3 36.7 2.1 7.9 2.3 3.2 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.9 CDJ60391.1 - 0.00012 22.2 1.0 0.00013 22.2 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) THOC2_N PF16134.5 CDJ60391.1 - 0.0081 14.8 3.5 0.012 14.3 3.5 1.1 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus CENP-B_dimeris PF09026.10 CDJ60391.1 - 0.013 15.9 3.4 0.021 15.2 3.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GDA1_CD39 PF01150.17 CDJ60391.1 - 0.015 14.0 0.2 0.28 9.8 0.1 2.3 2 1 1 3 3 3 0 GDA1/CD39 (nucleoside phosphatase) family Radial_spoke PF04712.12 CDJ60391.1 - 0.017 14.1 5.0 0.021 13.8 5.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Shadoo PF14999.6 CDJ60391.1 - 0.024 14.7 9.0 0.063 13.4 0.0 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective FAM176 PF14851.6 CDJ60391.1 - 0.024 14.3 4.3 0.034 13.8 4.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF4366 PF14283.6 CDJ60391.1 - 0.072 13.1 1.8 0.76 9.8 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FHIPEP PF00771.20 CDJ60391.1 - 0.12 10.8 1.3 0.15 10.5 1.3 1.1 1 0 0 1 1 1 0 FHIPEP family TRAP_alpha PF03896.16 CDJ60391.1 - 0.13 11.4 3.3 0.19 10.9 3.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1840 PF08895.11 CDJ60391.1 - 0.13 12.6 5.8 0.27 11.6 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) PI3K_1B_p101 PF10486.9 CDJ60391.1 - 0.14 9.9 0.5 0.17 9.6 0.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAXIP1_C PF15364.6 CDJ60391.1 - 0.15 12.4 6.9 0.21 11.9 6.9 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Zip PF02535.22 CDJ60391.1 - 0.15 11.2 0.8 0.27 10.4 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FancD2 PF14631.6 CDJ60391.1 - 0.17 9.3 4.4 0.21 9.0 4.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Tim54 PF11711.8 CDJ60391.1 - 0.2 10.4 4.8 0.25 10.1 4.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 CDJ60391.1 - 0.21 11.8 3.0 0.29 11.3 3.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 CDJ60391.1 - 0.22 11.4 7.0 0.32 10.9 7.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4518 PF15008.6 CDJ60391.1 - 0.23 10.6 2.5 0.29 10.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) PMSI1 PF15322.6 CDJ60391.1 - 0.36 10.2 3.5 0.55 9.6 3.5 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative NOA36 PF06524.12 CDJ60391.1 - 0.95 8.7 9.2 1.3 8.3 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein Chorion_2 PF03964.15 CDJ60391.1 - 1.1 10.2 4.8 4.3 8.2 0.7 2.2 2 0 0 2 2 2 0 Chorion family 2 SPC25 PF06703.11 CDJ60391.1 - 1.4 8.7 5.6 0.32 10.8 2.1 1.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Cytomega_UL84 PF06284.11 CDJ60391.1 - 1.7 7.0 4.0 2.2 6.6 4.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DNA_pol_phi PF04931.13 CDJ60391.1 - 2.6 6.0 9.7 3.3 5.7 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.18 CDJ60391.1 - 2.6 7.8 8.2 4.4 7.1 8.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 CDJ60391.1 - 3.8 6.8 11.5 5.2 6.4 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Phage_Gp23 PF10669.9 CDJ60391.1 - 4.9 7.5 11.6 7.7 6.9 11.6 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CDC45 PF02724.14 CDJ60391.1 - 6.3 5.0 8.5 7.9 4.6 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 CDJ60391.1 - 7 5.5 14.5 9.1 5.2 14.5 1.1 1 0 0 1 1 1 0 Paf1 zf-C2H2_jaz PF12171.8 CDJ60392.1 - 0.18 12.1 1.5 0.34 11.2 1.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDJ60392.1 - 0.25 11.9 1.5 0.68 10.5 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDJ60392.1 - 1 10.4 7.9 0.097 13.6 2.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PAT1 PF09770.9 CDJ60392.1 - 1.8 6.7 28.9 3.3 5.9 28.9 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GPCR_chapero_1 PF11904.8 CDJ60392.1 - 2.4 7.5 6.6 4.4 6.7 6.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone CDC45 PF02724.14 CDJ60392.1 - 3 6.0 10.2 5 5.3 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein MMR1 PF08505.10 CDJ60392.1 - 3.5 7.8 13.0 8.8 6.5 13.0 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peptidase_M24 PF00557.24 CDJ60393.1 - 1.5e-06 28.1 0.0 3.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 SUIM_assoc PF16619.5 CDJ60393.1 - 0.008 16.2 3.3 0.008 16.2 3.3 3.1 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Phostensin_N PF13916.6 CDJ60393.1 - 0.61 10.5 4.2 0.43 11.0 1.3 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Spt20 PF12090.8 CDJ60393.1 - 0.91 9.1 11.3 0.15 11.6 1.6 2.3 3 0 0 3 3 3 0 Spt20 family RCC1 PF00415.18 CDJ60394.1 - 2.2e-11 44.2 0.1 0.0021 18.7 0.0 5.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ60394.1 - 1.4e-06 28.0 2.2 0.0012 18.6 0.1 4.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Otopetrin PF03189.13 CDJ60394.1 - 0.00027 19.9 0.0 0.012 14.5 0.0 3.1 3 1 0 3 3 3 1 Otopetrin DDHD PF02862.17 CDJ60394.1 - 0.0092 16.2 34.9 0.057 13.6 0.4 5.9 6 0 0 6 6 6 4 DDHD domain DUF3801 PF12687.7 CDJ60394.1 - 0.61 10.1 41.7 0.13 12.3 2.0 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3801) Viral_P18 PF04521.13 CDJ60394.1 - 1.5 8.6 3.8 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2722 PF10846.8 CDJ60395.1 - 0.0048 15.9 1.5 0.0048 15.9 1.5 5.4 6 0 0 6 6 6 2 Protein of unknown function (DUF2722) Adaptin_binding PF10199.9 CDJ60395.1 - 0.0083 16.7 0.7 0.0083 16.7 0.7 4.6 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 Slu7 PF11708.8 CDJ60395.1 - 0.69 9.6 0.0 0.69 9.6 0.0 3.8 4 0 0 4 4 4 0 Pre-mRNA splicing Prp18-interacting factor Folliculin PF11704.8 CDJ60395.1 - 2.4 8.0 11.3 14 5.5 0.4 4.4 4 0 0 4 4 4 0 Vesicle coat protein involved in Golgi to plasma membrane transport MecA PF05389.12 CDJ60395.1 - 4.1 7.0 12.5 0.59 9.7 0.1 3.6 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) LRR_6 PF13516.6 CDJ60396.1 - 7.1e-08 31.9 13.3 0.49 10.6 0.0 8.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ60396.1 - 1.7e-06 28.3 8.9 0.36 11.3 0.1 5.8 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) Pkinase PF00069.25 CDJ60397.1 - 2.5e-15 56.6 0.0 1.7e-13 50.5 0.0 2.9 2 1 1 3 3 3 1 Protein kinase domain EDR1 PF14381.6 CDJ60397.1 - 8.9e-15 54.9 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase_Tyr PF07714.17 CDJ60397.1 - 4.2e-14 52.5 0.0 7.9e-10 38.5 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase LRR_6 PF13516.6 CDJ60397.1 - 0.00021 21.1 0.6 20 5.6 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 CDJ60397.1 - 0.003 17.9 0.9 30 5.7 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat APH PF01636.23 CDJ60397.1 - 0.0044 17.0 0.2 0.0044 17.0 0.2 3.4 4 0 0 4 4 4 1 Phosphotransferase enzyme family DUF4667 PF15700.5 CDJ60397.1 - 0.013 15.6 0.8 0.013 15.6 0.8 8.5 6 2 2 8 8 8 0 Domain of unknown function (DUF4667) HflK_N PF12221.8 CDJ60397.1 - 0.32 11.0 3.0 3.3 7.8 3.0 2.9 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Rep_fac-A_3 PF08661.11 CDJ60401.1 - 2.3e-09 37.6 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 DUF150_C PF17384.2 CDJ60401.1 - 0.075 13.2 1.4 0.2 11.8 0.1 2.1 2 1 0 2 2 2 0 RimP C-terminal SH3 domain tRNA_Me_trans PF03054.16 CDJ60402.1 - 5.5e-79 265.5 0.0 4.9e-71 239.4 0.0 2.6 2 1 0 2 2 2 2 tRNA methyl transferase DnaG_DnaB_bind PF08278.11 CDJ60402.1 - 0.019 15.5 1.1 0.16 12.6 0.1 2.8 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding SufE PF02657.15 CDJ60402.1 - 0.024 14.5 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Fe-S metabolism associated domain ThiI PF02568.14 CDJ60402.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Methyltransf_3 PF01596.17 CDJ60403.1 - 3.4e-20 72.1 0.0 2.9e-11 42.9 0.0 3.3 3 1 0 3 3 3 2 O-methyltransferase UPF0176_N PF17773.1 CDJ60403.1 - 6.6e-20 71.3 0.0 1.5e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CDJ60403.1 - 1.3e-11 44.7 10.3 1.3e-11 44.7 10.3 1.8 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 CDJ60403.1 - 1.5e-09 38.3 0.0 4.4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.6 CDJ60403.1 - 1e-07 32.9 0.1 1.1e-06 29.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ion_trans PF00520.31 CDJ60404.1 - 2.4e-22 79.4 20.5 3.3e-22 78.9 20.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDJ60404.1 - 0.004 15.9 11.9 0.0055 15.4 11.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel DENN PF02141.21 CDJ60406.1 - 2.4e-21 76.5 14.1 4.5e-18 65.9 10.2 2.7 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CDJ60406.1 - 0.00013 22.6 8.9 0.00045 20.9 0.1 3.4 3 0 0 3 3 3 2 uDENN domain Wzy_C_2 PF11846.8 CDJ60406.1 - 0.18 11.7 5.3 0.11 12.5 0.2 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Ank_4 PF13637.6 CDJ60408.1 - 0.00029 21.3 0.1 0.00089 19.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ60408.1 - 0.0018 18.8 0.2 0.0068 17.0 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_25 PF13649.6 CDJ60408.1 - 0.0052 17.5 0.2 0.14 12.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ60408.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain POR_N PF01855.19 CDJ60408.1 - 0.3 10.8 2.0 0.53 10.0 2.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF2362 PF10154.9 CDJ60409.1 - 5.7e-07 28.9 0.0 5.7e-07 28.9 0.0 3.7 3 2 0 3 3 3 2 Uncharacterized conserved protein (DUF2362) REV PF00424.18 CDJ60409.1 - 0.0093 16.0 5.9 0.011 15.7 0.4 3.1 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) DHC_N2 PF08393.13 CDJ60412.1 - 2.8e-80 270.3 1.0 2.8e-80 270.3 1.0 2.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 RskA PF10099.9 CDJ60412.1 - 0.00085 19.7 34.1 0.064 13.5 19.1 2.7 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ60412.1 - 0.0035 16.3 4.1 0.0035 16.3 4.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TERB2 PF15101.6 CDJ60412.1 - 0.0038 17.3 8.5 0.3 11.1 1.1 2.5 2 0 0 2 2 2 2 Telomere-associated protein TERB2 DDHD PF02862.17 CDJ60412.1 - 0.0082 16.3 9.3 0.51 10.5 1.3 2.7 2 0 0 2 2 2 2 DDHD domain TFIIA PF03153.13 CDJ60412.1 - 0.026 14.5 41.9 0.2 11.6 12.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 CDJ60412.1 - 0.026 14.9 9.7 0.8 10.1 0.5 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like SAGA-Tad1 PF12767.7 CDJ60412.1 - 0.035 13.8 7.4 0.26 11.0 0.3 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Baculo_PEP_C PF04513.12 CDJ60412.1 - 0.037 14.1 9.2 1.2 9.2 0.0 4.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ctr PF04145.15 CDJ60412.1 - 1.2 9.8 5.5 22 5.7 0.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Spt20 PF12090.8 CDJ60412.1 - 1.5 8.4 48.5 3.6 7.1 21.2 2.5 2 0 0 2 2 2 0 Spt20 family CPSF100_C PF13299.6 CDJ60412.1 - 1.7 8.8 13.9 1.7 8.8 0.4 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Med15 PF09606.10 CDJ60412.1 - 3.9 6.0 41.9 0.33 9.6 16.2 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hydin_ADK PF17213.3 CDJ60412.1 - 3.9 7.7 20.6 9.4 6.5 8.9 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain MMR1 PF08505.10 CDJ60412.1 - 6 7.1 16.8 7.3 6.8 4.4 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein BORG_CEP PF14957.6 CDJ60412.1 - 6.5 7.9 8.5 19 6.4 0.5 2.9 2 0 0 2 2 2 0 Cdc42 effector FAM60A PF15396.6 CDJ60412.1 - 6.7 6.7 12.2 6 6.8 3.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF2076 PF09849.9 CDJ60412.1 - 7.9 6.4 43.0 0.019 15.0 14.2 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2076) SpoIIP PF07454.11 CDJ60412.1 - 8.7 5.7 14.2 3.4 7.1 2.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PepSY_TM PF03929.16 CDJ60412.1 - 8.8 5.9 7.9 16 5.0 2.2 2.5 2 0 0 2 2 2 0 PepSY-associated TM region DUF4228 PF14009.6 CDJ60412.1 - 9.7 6.5 10.9 11 6.3 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) AAA_6 PF12774.7 CDJ60413.1 - 1.1e-97 326.9 4.5 6.3e-96 321.2 0.0 3.9 3 1 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 CDJ60413.1 - 4.1e-58 195.9 0.0 2.8e-49 167.1 0.0 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 CDJ60413.1 - 1e-48 165.9 4.5 6.7e-38 130.5 0.1 3.7 4 0 0 4 4 3 2 P-loop containing dynein motor region D4 MT PF12777.7 CDJ60413.1 - 7.8e-43 146.8 9.7 1.3e-42 146.1 9.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDJ60413.1 - 7.6e-23 80.9 0.0 1.2e-21 77.0 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CDJ60413.1 - 9.1e-22 77.3 0.4 9.1e-22 77.3 0.4 4.4 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CDJ60413.1 - 1.7e-18 67.0 0.2 7.5e-18 64.9 0.0 2.2 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ60413.1 - 1.4e-15 57.3 0.0 4.5e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ60413.1 - 1.1e-13 51.4 0.0 0.0032 17.5 0.0 5.8 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_C PF18199.1 CDJ60413.1 - 6.4e-12 45.3 0.2 6.4e-12 45.3 0.2 4.1 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA PF00004.29 CDJ60413.1 - 1.1e-10 42.1 0.5 0.00094 19.6 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ60413.1 - 3.1e-08 34.0 2.9 0.00088 19.6 0.0 5.1 4 0 0 4 4 3 1 AAA domain Dynein_AAA_lid PF17852.1 CDJ60413.1 - 3.8e-08 33.5 0.0 3.5e-07 30.4 0.0 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 CDJ60413.1 - 1.4e-05 25.6 6.6 0.013 16.0 0.0 4.9 5 0 0 5 5 4 2 AAA domain Sigma54_activat PF00158.26 CDJ60413.1 - 0.00012 21.8 4.9 0.017 14.8 0.0 4.4 5 0 0 5 5 3 1 Sigma-54 interaction domain AAA_19 PF13245.6 CDJ60413.1 - 0.00013 22.3 1.9 14 6.0 0.0 4.7 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 CDJ60413.1 - 0.00014 21.8 0.2 0.04 13.9 0.0 3.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CDJ60413.1 - 0.00014 21.0 6.3 0.042 12.9 0.0 4.7 5 0 0 5 5 5 2 Type II/IV secretion system protein Rad17 PF03215.15 CDJ60413.1 - 0.00015 21.7 0.9 0.28 11.1 0.1 3.7 3 0 0 3 3 3 1 Rad17 P-loop domain cobW PF02492.19 CDJ60413.1 - 0.00025 20.7 0.2 0.0076 15.9 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CDJ60413.1 - 0.00036 20.9 0.0 0.00036 20.9 0.0 9.5 9 3 1 10 10 7 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDJ60413.1 - 0.001 19.0 5.5 0.08 12.8 0.1 3.7 4 0 0 4 4 3 1 RsgA GTPase AAA_29 PF13555.6 CDJ60413.1 - 0.0014 18.4 1.9 4.4 7.1 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain UPF0242 PF06785.11 CDJ60413.1 - 0.0016 18.6 6.6 0.0016 18.6 6.6 4.6 4 0 0 4 4 3 1 Uncharacterised protein family (UPF0242) N-terminus ATPase_2 PF01637.18 CDJ60413.1 - 0.0021 18.0 0.1 0.15 12.0 0.0 3.2 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CDJ60413.1 - 0.0031 17.9 0.2 2 8.9 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.6 CDJ60413.1 - 0.0077 16.3 0.0 0.15 12.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDJ60413.1 - 0.0082 15.9 25.3 0.076 12.7 0.0 5.5 5 0 0 5 5 4 3 AAA domain Mg_chelatase PF01078.21 CDJ60413.1 - 0.0095 15.3 0.3 0.7 9.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDJ60413.1 - 0.012 14.8 0.5 2.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Adaptin_binding PF10199.9 CDJ60413.1 - 0.027 15.1 0.1 0.027 15.1 0.1 4.5 3 2 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Viral_helicase1 PF01443.18 CDJ60413.1 - 0.027 14.2 1.3 37 4.0 0.0 3.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CDJ60413.1 - 0.031 13.6 3.8 0.94 8.7 0.1 3.5 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 CDJ60413.1 - 0.035 13.8 6.4 4.5 7.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain dNK PF01712.19 CDJ60413.1 - 0.039 13.8 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activ_2 PF14532.6 CDJ60413.1 - 0.059 13.5 4.2 0.11 12.6 0.1 3.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Roc PF08477.13 CDJ60413.1 - 0.086 13.1 3.9 0.12 12.6 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CDJ60413.1 - 0.11 12.3 2.9 11 5.8 0.0 3.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EOS1 PF12326.8 CDJ60413.1 - 0.19 11.7 2.7 0.17 11.8 0.1 2.3 2 0 0 2 2 1 0 N-glycosylation protein AAA_33 PF13671.6 CDJ60413.1 - 0.4 10.8 0.0 0.4 10.8 0.0 5.5 8 0 0 8 8 3 0 AAA domain Cytidylate_kin PF02224.18 CDJ60413.1 - 0.61 9.8 4.7 3.3 7.4 0.1 3.3 3 0 0 3 3 2 0 Cytidylate kinase PRK PF00485.18 CDJ60413.1 - 1.1 8.9 4.5 39 3.9 0.0 3.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 CDJ60413.1 - 1.1 9.1 11.2 0.44 10.4 0.0 4.5 5 0 0 5 5 3 0 NACHT domain AAA_28 PF13521.6 CDJ60413.1 - 1.3 9.3 0.0 1.3 9.3 0.0 5.5 6 0 0 6 6 3 0 AAA domain Ebp2 PF05890.12 CDJ60414.1 - 3.8e-20 72.6 21.2 5.9e-17 62.1 12.1 3.3 3 0 0 3 3 3 2 Eukaryotic rRNA processing protein EBP2 TFIIA PF03153.13 CDJ60415.1 - 0.0053 16.8 45.6 0.0053 16.8 45.6 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3267 PF11667.8 CDJ60415.1 - 0.2 12.0 2.4 0.57 10.5 2.4 1.7 1 0 0 1 1 1 0 Putative zincin peptidase LAP1C PF05609.12 CDJ60415.1 - 5.8 5.9 22.5 10 5.1 22.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAN_4 PF14295.6 CDJ60416.1 - 4.6e-50 167.3 69.2 6.6e-06 25.9 3.8 11.7 11 0 0 11 11 11 11 PAN domain PAN_1 PF00024.26 CDJ60416.1 - 7.5e-46 154.0 76.8 6.1e-07 29.3 1.0 12.1 8 3 4 12 12 12 11 PAN domain PAN_2 PF08276.11 CDJ60416.1 - 6.3e-05 23.0 65.7 0.24 11.5 0.8 11.5 11 0 0 11 11 11 6 PAN-like domain PAN_3 PF08277.12 CDJ60416.1 - 0.00083 19.1 0.4 0.00083 19.1 0.4 10.8 11 0 0 11 11 11 4 PAN-like domain Sporozoite_P67 PF05642.11 CDJ60416.1 - 0.39 8.8 7.1 0.93 7.5 7.1 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TSP_1 PF00090.19 CDJ60417.1 - 0.0012 19.0 0.4 0.0012 19.0 0.4 3.7 3 0 0 3 3 3 1 Thrombospondin type 1 domain Caldesmon PF02029.15 CDJ60417.1 - 0.059 12.1 34.4 0.007 15.2 15.5 2.3 2 0 0 2 2 2 0 Caldesmon SDA1 PF05285.12 CDJ60417.1 - 0.26 10.7 25.7 0.13 11.6 1.8 3.4 3 0 0 3 3 3 0 SDA1 Na_trans_assoc PF06512.13 CDJ60417.1 - 1.7 8.9 26.2 2.5 8.3 18.0 2.6 2 0 0 2 2 2 0 Sodium ion transport-associated MRNIP PF15749.5 CDJ60417.1 - 3.5 8.4 33.9 0.55 11.0 8.2 3.8 3 0 0 3 3 3 0 MRN-interacting protein Eapp_C PF10238.9 CDJ60417.1 - 3.6 7.7 25.0 0.61 10.2 4.9 4.0 4 0 0 4 4 4 0 E2F-associated phosphoprotein RNase_H2_suC PF08615.11 CDJ60417.1 - 4 7.6 11.9 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3405 PF11885.8 CDJ60417.1 - 4.4 5.8 22.1 0.017 13.8 3.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3405) RPN2_C PF18004.1 CDJ60417.1 - 5.6 6.9 27.2 0.77 9.7 1.2 3.6 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 CDJ60417.1 - 8.6 5.0 23.3 1.2 7.8 4.1 3.3 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 TAFII55_N PF04658.13 CDJ60418.1 - 1.4e-17 63.9 0.1 1.8e-16 60.2 0.0 2.9 2 1 0 2 2 2 1 TAFII55 protein conserved region Hydrolase_4 PF12146.8 CDJ60419.1 - 1.6e-16 60.3 0.1 1.7e-13 50.4 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ60419.1 - 6.2e-15 55.5 0.3 1.4e-11 44.6 0.5 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDJ60419.1 - 5.5e-11 43.5 0.3 1.1e-10 42.6 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CDJ60419.1 - 0.0001 21.1 0.0 0.024 13.3 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 CDJ60419.1 - 0.00011 21.9 0.0 0.00031 20.4 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CDJ60419.1 - 0.0005 19.6 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.12 CDJ60419.1 - 0.001 18.2 0.0 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 CDJ60419.1 - 0.0029 17.4 0.1 0.015 15.1 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CDJ60419.1 - 0.0038 17.1 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CDJ60419.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S15 PF02129.18 CDJ60419.1 - 0.006 16.2 0.0 0.039 13.5 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 CDJ60419.1 - 0.0097 15.8 0.0 0.22 11.4 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 CDJ60419.1 - 0.013 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 CDJ60419.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 CDJ60419.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 CDJ60419.1 - 0.061 13.4 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF818 PF05677.12 CDJ60419.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) UPF0227 PF05728.12 CDJ60419.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pex14_N PF04695.13 CDJ60422.1 - 1.8 9.2 7.8 1.3 9.7 0.2 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Histone PF00125.24 CDJ60423.1 - 1.3e-11 45.0 0.1 1.7e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDJ60423.1 - 4.6e-11 42.3 0.2 7.4e-11 41.6 0.2 1.4 1 1 0 1 1 1 1 C-terminus of histone H2A Suppressor_APC PF11414.8 CDJ60424.1 - 0.0035 17.4 3.0 0.0048 16.9 3.0 1.1 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein APG6_N PF17675.1 CDJ60424.1 - 0.0041 17.6 7.5 0.0058 17.2 7.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region NleF_casp_inhib PF16809.5 CDJ60424.1 - 0.012 15.5 1.7 0.013 15.4 1.7 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor DUF4200 PF13863.6 CDJ60424.1 - 0.013 15.9 8.2 0.016 15.6 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PqqD PF05402.12 CDJ60424.1 - 0.024 14.9 0.5 0.039 14.2 0.2 1.5 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Arc_C PF18162.1 CDJ60424.1 - 0.024 14.5 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Arc C-lobe COX16 PF14138.6 CDJ60424.1 - 0.027 15.0 1.0 0.037 14.5 1.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Nup88 PF10168.9 CDJ60424.1 - 0.076 10.8 5.6 0.079 10.8 5.6 1.0 1 0 0 1 1 1 0 Nuclear pore component UPF0242 PF06785.11 CDJ60424.1 - 0.079 13.1 6.4 0.088 12.9 6.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CDJ60424.1 - 0.098 12.7 2.1 0.12 12.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CDJ60424.1 - 0.16 12.1 9.8 0.2 11.8 2.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.18 CDJ60424.1 - 0.18 11.1 1.4 0.2 11.0 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 CDJ60424.1 - 0.74 9.0 4.0 0.79 8.9 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 CDJ60424.1 - 0.85 9.4 6.0 0.98 9.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TIP120 PF08623.10 CDJ60426.1 - 0.028 14.2 0.8 3.5 7.4 0.1 3.4 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) HEAT PF02985.22 CDJ60426.1 - 0.034 14.4 2.9 18 5.9 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat TPR_7 PF13176.6 CDJ60427.1 - 0.00032 20.5 1.7 0.034 14.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CDJ60427.1 - 0.0033 16.5 1.0 0.05 12.6 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region TPR_19 PF14559.6 CDJ60427.1 - 1.7 9.2 9.8 4 8.0 0.1 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 CDJ60428.1 - 8.1e-05 22.8 0.0 0.77 10.1 0.0 4.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ60428.1 - 0.046 14.6 2.9 0.12 13.3 0.1 3.2 2 1 0 2 2 2 0 WD domain, G-beta repeat TPH PF13868.6 CDJ60429.1 - 9e-12 44.2 140.8 9e-12 44.2 140.8 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain FAP206 PF12018.8 CDJ60433.1 - 1.6e-14 54.1 0.1 3.5e-05 23.5 0.0 3.9 3 0 0 3 3 3 3 Domain of unknown function YHS PF04945.13 CDJ60433.1 - 0.022 14.8 0.1 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 YHS domain PIEZO PF15917.5 CDJ60433.1 - 1.6 8.2 6.4 4 6.9 0.6 3.1 2 0 0 2 2 2 0 Piezo DUF5302 PF17227.2 CDJ60433.1 - 2 9.5 10.7 0.31 12.1 4.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5302) AMA-1 PF02430.15 CDJ60434.1 - 1.5e-67 228.6 0.5 5.5e-67 226.7 1.6 1.3 2 0 0 2 2 2 1 Apical membrane antigen 1 CD34_antigen PF06365.12 CDJ60434.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family WD40 PF00400.32 CDJ60435.1 - 2.2e-09 37.8 10.5 0.00011 22.8 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3040 PF11239.8 CDJ60435.1 - 0.0074 16.5 1.3 0.0074 16.5 1.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) HPS6 PF15702.5 CDJ60435.1 - 0.17 9.9 0.0 0.26 9.2 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein ABC1 PF03109.16 CDJ60436.1 - 1.3e-05 25.3 1.3 3.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 ABC1 family SR-25 PF10500.9 CDJ60436.1 - 0.0029 17.3 18.6 0.0029 17.3 18.6 11.7 4 3 6 10 10 10 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ60436.1 - 0.0044 17.3 2.7 0.0044 17.3 2.7 13.6 5 3 6 11 11 11 1 Anti-sigma-K factor rskA RskA PF10099.9 CDJ60439.1 - 5.3e-07 30.1 23.1 1.2e-05 25.7 4.6 4.0 2 1 2 4 4 4 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ60439.1 - 2.4e-05 23.5 5.1 2.4e-05 23.5 5.1 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) DUF4148 PF13663.6 CDJ60439.1 - 0.001 19.2 6.8 0.11 12.7 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) Shadoo PF14999.6 CDJ60439.1 - 0.0023 18.0 6.9 0.32 11.1 5.3 2.2 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective CDC27 PF09507.10 CDJ60439.1 - 0.0042 16.5 30.1 0.0042 16.5 30.1 2.1 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Pex14_N PF04695.13 CDJ60439.1 - 0.02 15.5 4.4 0.02 15.5 4.4 3.4 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4179 PF13786.6 CDJ60439.1 - 0.56 10.7 0.0 0.56 10.7 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) Fusion_gly PF00523.18 CDJ60440.1 - 0.05 11.9 0.1 0.1 10.8 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 YccV-like PF08755.11 CDJ60441.1 - 1.1e-14 54.7 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.13 CDJ60441.1 - 5.1e-12 46.6 0.1 3.2e-05 24.9 0.0 3.2 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CDJ60441.1 - 0.0034 17.1 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PhdYeFM_antitox PF02604.19 CDJ60442.1 - 1.4 8.8 7.0 2.4 8.0 0.6 2.4 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system TPR_MalT PF17874.1 CDJ60443.1 - 1.2e-07 31.4 3.1 0.00026 20.5 0.2 2.1 2 0 0 2 2 2 2 MalT-like TPR region TPR_12 PF13424.6 CDJ60443.1 - 6.4e-07 29.6 2.5 0.014 15.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60443.1 - 4.2e-05 23.4 2.1 0.09 13.0 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60443.1 - 0.0011 18.9 0.6 0.081 13.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60443.1 - 0.01 15.6 0.0 0.87 9.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60443.1 - 0.014 15.4 0.2 1.3 9.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN6_N PF18055.1 CDJ60443.1 - 0.058 13.8 0.4 0.16 12.3 0.4 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_19 PF14559.6 CDJ60443.1 - 0.089 13.3 1.5 0.26 11.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat UCH PF00443.29 CDJ60444.1 - 3.2e-35 121.9 0.0 3.2e-35 121.9 0.0 3.7 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase ABC_tran PF00005.27 CDJ60445.1 - 1.6e-35 122.6 0.9 5e-22 78.9 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CDJ60445.1 - 2.5e-19 69.1 1.8 2.5e-19 69.1 1.8 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ60445.1 - 2.2e-13 50.7 9.1 4.6e-06 26.7 0.1 3.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDJ60445.1 - 1.1e-07 31.6 6.9 0.00011 21.7 0.1 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDJ60445.1 - 0.00082 19.9 6.3 0.02 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDJ60445.1 - 0.0013 19.3 3.9 0.017 15.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 CDJ60445.1 - 0.0022 17.8 10.5 0.054 13.2 0.2 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CDJ60445.1 - 0.0028 17.3 0.2 0.0094 15.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDJ60445.1 - 0.006 16.9 0.4 0.082 13.2 0.0 2.9 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 CDJ60445.1 - 0.0063 16.7 0.0 0.025 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain ATP-synt_10 PF05176.14 CDJ60445.1 - 0.027 13.7 0.2 0.052 12.8 0.2 1.5 1 0 0 1 1 1 0 ATP10 protein RsgA_GTPase PF03193.16 CDJ60445.1 - 0.03 14.2 0.1 0.074 13.0 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CDJ60445.1 - 0.037 14.1 0.3 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 CDJ60445.1 - 0.27 11.3 1.7 0.68 10.0 0.0 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain RVT_1 PF00078.27 CDJ60446.1 - 1.8e-05 24.4 0.0 3.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 CDJ60447.1 - 0.0025 18.1 0.0 0.0039 17.5 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Chromo PF00385.24 CDJ60447.1 - 0.0033 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SBDS_C PF09377.10 CDJ60448.1 - 1.9e-16 60.1 0.0 1.9e-16 60.1 0.0 2.5 2 1 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 CDJ60448.1 - 2.9e-12 46.5 0.0 6.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein GDI PF00996.18 CDJ60449.1 - 2.6e-203 675.4 0.0 3.1e-203 675.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CDJ60449.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DAO PF01266.24 CDJ60449.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ60449.1 - 0.15 12.3 0.7 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Dehydrin PF00257.19 CDJ60451.1 - 0.05 14.1 0.8 0.075 13.6 0.8 1.3 1 0 0 1 1 1 0 Dehydrin Zw10 PF06248.13 CDJ60454.1 - 0.018 13.7 11.7 0.077 11.6 7.7 3.2 3 1 0 3 3 3 0 Centromere/kinetochore Zw10 PIG-X PF08320.12 CDJ60456.1 - 1.1e-16 61.4 0.0 2.4e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 PIG-X / PBN1 CDK2AP PF09806.9 CDJ60456.1 - 0.038 14.1 6.4 2.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Herpes_LP PF03363.13 CDJ60456.1 - 0.088 12.6 3.4 0.14 11.9 2.3 1.8 1 1 0 2 2 2 0 Herpesvirus leader protein DUF5470 PF17564.2 CDJ60456.1 - 0.81 9.9 5.2 2.4 8.4 1.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5470) TFIIA PF03153.13 CDJ60458.1 - 0.0035 17.4 32.7 0.0035 17.4 32.7 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3576 PF12100.8 CDJ60458.1 - 0.21 11.7 3.6 0.84 9.8 3.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) LMBR1 PF04791.16 CDJ60458.1 - 1 8.2 15.1 0.074 12.0 0.2 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein Sin_N PF04801.13 CDJ60459.1 - 1.8e-06 27.4 14.2 1.8e-06 27.4 14.2 5.9 5 1 0 5 5 5 2 Sin-like protein conserved region BAF1_ABF1 PF04684.13 CDJ60459.1 - 0.00018 20.7 4.6 0.00018 20.7 4.6 6.0 5 1 1 6 6 6 2 BAF1 / ABF1 chromatin reorganising factor Utp14 PF04615.13 CDJ60459.1 - 0.00053 18.7 6.7 0.00053 18.7 6.7 3.9 2 2 1 3 3 3 1 Utp14 protein Adaptin_binding PF10199.9 CDJ60459.1 - 0.01 16.4 3.9 0.01 16.4 3.9 7.4 3 3 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 RskA PF10099.9 CDJ60459.1 - 1.6 9.0 0.0 1.6 9.0 0.0 10.9 3 2 4 8 8 8 0 Anti-sigma-K factor rskA UCH PF00443.29 CDJ60460.1 - 2.4e-23 82.9 0.0 6.7e-22 78.2 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Macoilin PF09726.9 CDJ60460.1 - 7.4e-06 24.8 0.2 7.4e-06 24.8 0.2 5.8 3 2 2 6 6 6 1 Macoilin family TraT PF05818.12 CDJ60460.1 - 0.057 13.1 0.1 0.057 13.1 0.1 6.5 7 2 1 8 8 8 0 Enterobacterial TraT complement resistance protein N6_N4_Mtase PF01555.18 CDJ60460.1 - 0.87 9.2 4.7 1.7 8.3 4.7 1.4 1 0 0 1 1 1 0 DNA methylase EIIBC-GUT_N PF03612.14 CDJ60460.1 - 1.3 8.7 6.8 4.4 7.0 6.8 1.9 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 CDJ60460.1 - 2.3 7.8 49.5 0.15 11.6 5.0 3.0 3 0 0 3 3 3 0 Spt20 family TFIIA PF03153.13 CDJ60461.1 - 0.057 13.4 10.0 0.058 13.4 10.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CDJ60461.1 - 0.2 12.6 6.0 0.26 12.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RAB3GAP2_N PF14655.6 CDJ60461.1 - 0.96 8.6 4.8 1.1 8.4 4.8 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.10 CDJ60461.1 - 1.2 7.7 21.9 1.4 7.5 21.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.8 CDJ60461.1 - 1.7 7.5 19.9 1.9 7.4 19.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CDJ60461.1 - 1.9 8.0 20.7 2.4 7.7 20.7 1.0 1 0 0 1 1 1 0 Spt20 family DNA_pol3_a_NII PF11490.8 CDJ60462.1 - 0.01 15.7 5.5 0.01 15.7 5.5 4.5 4 0 0 4 4 4 0 DNA polymerase III polC-type N-terminus II Ank_2 PF12796.7 CDJ60464.1 - 1.3e-25 89.8 4.3 4.5e-13 49.6 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ60464.1 - 4.3e-19 68.1 1.2 4e-06 27.0 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDJ60464.1 - 7.8e-19 65.8 0.2 5.6e-05 23.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CDJ60464.1 - 8.4e-18 64.5 0.6 1.3e-12 48.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDJ60464.1 - 3e-15 56.1 0.2 3e-05 24.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NAAA-beta PF15508.6 CDJ60464.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GTP1_OBG PF01018.22 CDJ60466.1 - 5.5e-26 91.0 6.7 3.5e-24 85.1 6.7 2.4 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CDJ60466.1 - 1.2e-06 28.5 0.0 1.3e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CDJ60466.1 - 0.00014 21.3 0.0 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CDJ60466.1 - 0.00032 20.6 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CDJ60466.1 - 0.0033 17.0 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDJ60466.1 - 0.035 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2561 PF10812.8 CDJ60466.1 - 0.038 14.0 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) NOG1 PF06858.14 CDJ60466.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) SRPRB PF09439.10 CDJ60466.1 - 0.055 12.9 0.0 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CDJ60466.1 - 0.083 12.8 0.0 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 CDJ60466.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 CDJ60466.1 - 4.2 7.8 0.0 4.2 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain IMS PF00817.20 CDJ60467.1 - 1.3e-39 135.6 0.3 2.8e-39 134.5 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CDJ60467.1 - 3.4e-12 47.1 0.4 1.3e-11 45.2 0.4 1.9 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDJ60467.1 - 3.5e-05 23.9 0.0 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif Acetyltransf_6 PF13480.7 CDJ60467.1 - 6.2 7.0 5.7 54 3.9 0.2 3.8 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain Folate_rec PF03024.14 CDJ60468.1 - 8.6e-08 32.2 0.4 1.6e-07 31.4 0.4 1.4 1 0 0 1 1 1 1 Folate receptor family Synaphin PF05835.12 CDJ60468.1 - 0.037 14.3 3.8 0.055 13.8 3.8 1.2 1 0 0 1 1 1 0 Synaphin protein DUF1828 PF08861.10 CDJ60468.1 - 0.076 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF1828 MORN PF02493.20 CDJ60469.1 - 1.3e-11 43.6 11.3 0.00046 19.9 0.0 5.5 5 0 0 5 5 5 4 MORN repeat AP2 PF00847.20 CDJ60469.1 - 0.047 13.9 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 AP2 domain NDK PF00334.19 CDJ60473.1 - 1e-19 70.9 0.0 7.1e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DDHD PF02862.17 CDJ60473.1 - 6.5 6.8 7.5 26 4.9 0.1 3.4 4 0 0 4 4 4 0 DDHD domain RRM_1 PF00076.22 CDJ60474.1 - 2.2e-15 56.2 0.0 4.8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CDJ60474.1 - 4e-14 52.4 0.1 7.7e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Surp module cwf21 PF08312.12 CDJ60474.1 - 1e-13 51.2 5.2 1e-13 51.2 5.2 2.3 3 0 0 3 3 3 1 cwf21 domain CTK3 PF12243.8 CDJ60474.1 - 0.00035 20.6 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Herpes_UL14 PF03580.14 CDJ60474.1 - 0.48 10.7 11.2 0.53 10.5 5.0 2.6 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Tubulin PF00091.25 CDJ60475.1 - 9.9e-25 87.9 0.0 1.4e-17 64.6 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CDJ60475.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Clp_N PF02861.20 CDJ60475.1 - 0.076 13.2 0.1 2.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component E1-E2_ATPase PF00122.20 CDJ60476.1 - 3.9e-40 137.3 0.2 8e-40 136.3 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDJ60476.1 - 1.1e-18 68.3 0.2 3.1e-18 66.8 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ60476.1 - 4.1e-11 42.4 0.0 9.7e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ60476.1 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) FTSW_RODA_SPOVE PF01098.19 CDJ60476.1 - 0.068 12.2 0.2 0.14 11.2 0.1 1.5 2 0 0 2 2 2 0 Cell cycle protein Rootletin PF15035.6 CDJ60477.1 - 0.013 15.5 1.9 0.026 14.6 1.9 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Transposase_31 PF04754.12 CDJ60477.1 - 0.14 11.7 0.7 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 Putative transposase, YhgA-like EF-hand_7 PF13499.6 CDJ60478.1 - 5.7e-15 55.5 0.0 3.8e-11 43.3 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60478.1 - 8e-14 50.3 0.5 1.6e-05 24.4 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDJ60478.1 - 8.5e-14 50.0 0.1 6.9e-07 28.4 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CDJ60478.1 - 4e-09 35.5 0.1 2.3e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ60478.1 - 3.8e-07 29.8 0.3 0.035 13.9 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDJ60478.1 - 0.00085 19.6 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDJ60478.1 - 0.1 12.5 0.1 22 4.9 0.0 2.9 2 1 1 3 3 3 0 Caleosin related protein EF-hand_9 PF14658.6 CDJ60478.1 - 0.15 12.4 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain HAP2-GCS1 PF10699.9 CDJ60479.1 - 2.3e-09 37.1 0.3 1.4e-08 34.6 0.1 2.4 2 0 0 2 2 2 1 Male gamete fusion factor DUF2649 PF10854.8 CDJ60479.1 - 0.086 13.2 0.4 0.24 11.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) SAS4 PF15460.6 CDJ60479.1 - 0.66 10.1 5.6 1.3 9.2 5.6 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 FAM176 PF14851.6 CDJ60480.1 - 0.004 16.8 0.2 0.0043 16.7 0.2 1.0 1 0 0 1 1 1 1 FAM176 family TMEM208_SND2 PF05620.11 CDJ60480.1 - 0.028 14.2 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 eIF2A PF08662.11 CDJ60481.1 - 1.5e-40 139.1 0.0 6.8e-35 120.7 0.0 3.7 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A GYF PF02213.16 CDJ60481.1 - 1.8e-15 56.4 0.3 3.9e-15 55.2 0.3 1.7 1 0 0 1 1 1 1 GYF domain RNase_T PF00929.24 CDJ60482.1 - 1.9e-29 103.3 0.0 2.2e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CDJ60483.1 - 1.9e-34 118.9 0.0 3.5e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDJ60483.1 - 1e-11 44.6 0.0 2.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDJ60483.1 - 0.031 15.0 0.1 0.37 11.5 0.0 2.9 2 1 0 2 2 2 0 PMC2NT (NUC016) domain RAP1 PF07218.11 CDJ60483.1 - 7.3 4.7 5.6 11 4.1 5.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spc7 PF08317.11 CDJ60485.1 - 0.00053 19.0 0.8 0.00067 18.6 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein LZ3wCH PF18517.1 CDJ60485.1 - 0.00084 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Mnd1 PF03962.15 CDJ60485.1 - 0.0049 17.1 0.1 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Mnd1 HTH domain ABC_tran_CTD PF16326.5 CDJ60485.1 - 0.026 14.7 3.2 0.044 14.0 3.2 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Methyltr_RsmB-F PF01189.17 CDJ60486.1 - 1.8e-29 102.8 0.0 2.8e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 CDJ60486.1 - 5.9e-09 35.6 0.0 8.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CDJ60486.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 CDJ60486.1 - 1.8e-05 25.1 0.0 3.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 CDJ60486.1 - 0.00014 22.5 0.0 0.00028 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDJ60486.1 - 0.0084 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 CDJ60486.1 - 0.015 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 CDJ60486.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PASTA PF03793.19 CDJ60486.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 PASTA domain FtsJ PF01728.19 CDJ60486.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Skp1_POZ PF03931.15 CDJ60487.1 - 2.6e-09 37.1 0.0 7.3e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Patatin PF01734.22 CDJ60488.1 - 9.8e-27 94.5 4.8 2.4e-26 93.2 2.5 2.9 2 0 0 2 2 2 1 Patatin-like phospholipase NAD_binding_8 PF13450.6 CDJ60489.1 - 1.8e-09 37.7 0.1 7.5e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDJ60489.1 - 7.2e-08 32.1 0.1 3.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 CDJ60489.1 - 2.9e-06 27.1 0.1 7.7e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 CDJ60489.1 - 2.2e-05 23.5 0.1 3.3e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 CDJ60489.1 - 0.0018 17.5 0.1 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ60489.1 - 0.003 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CDJ60489.1 - 0.005 16.8 0.2 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CDJ60489.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDJ60489.1 - 0.022 15.3 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDJ60489.1 - 0.034 13.3 0.3 0.034 13.3 0.3 2.2 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 CDJ60489.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MTBP_C PF14920.6 CDJ60489.1 - 0.29 10.8 3.0 0.85 9.3 0.5 2.8 2 0 0 2 2 2 0 MDM2-binding Myosin_head PF00063.21 CDJ60490.1 - 1.9e-124 416.4 0.0 1.7e-86 291.0 0.0 2.0 1 1 1 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 CDJ60490.1 - 0.00093 19.6 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ60490.1 - 0.0067 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDJ60490.1 - 0.0079 15.5 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.7 CDJ60490.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Hpr_kinase_C PF07475.12 CDJ60490.1 - 0.2 11.2 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myosin_head PF00063.21 CDJ60491.1 - 1.1e-14 53.7 0.0 1.4e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Fil_haemagg PF05594.14 CDJ60491.1 - 1.7 9.2 8.1 0.28 11.7 0.7 2.6 2 1 0 2 2 2 0 Haemagluttinin repeat Spc7 PF08317.11 CDJ60492.1 - 0.0019 17.1 17.8 0.0028 16.6 17.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 CDJ60492.1 - 0.0068 16.4 7.8 0.029 14.4 1.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDJ60492.1 - 0.014 15.9 24.3 0.049 14.1 24.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 CDJ60492.1 - 0.1 12.8 19.1 1 9.6 19.2 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CDJ60492.1 - 0.19 11.2 8.6 0.23 11.0 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 CDJ60492.1 - 0.38 10.7 14.0 0.62 10.0 0.7 3.1 1 1 1 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 CDJ60492.1 - 0.54 9.5 12.5 0.72 9.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM75 PF14650.6 CDJ60492.1 - 0.62 9.6 4.1 1.1 8.7 4.0 1.5 1 1 0 1 1 1 0 FAM75 family DUF4449 PF14613.6 CDJ60492.1 - 0.73 9.9 10.2 0.5 10.5 7.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) FlxA PF14282.6 CDJ60492.1 - 1 9.4 9.9 3.9 7.5 7.2 2.3 1 1 1 2 2 2 0 FlxA-like protein GAS PF13851.6 CDJ60492.1 - 1.2 8.4 23.9 0.37 10.1 14.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CDJ60492.1 - 1.3 9.4 19.2 0.29 11.6 2.0 2.0 1 1 1 2 2 2 0 Fez1 Swi5 PF07061.11 CDJ60492.1 - 1.4 9.1 11.3 0.96 9.6 0.4 3.2 2 1 1 3 3 3 0 Swi5 UPF0565 PF10561.9 CDJ60492.1 - 1.5 8.0 6.3 2.1 7.4 6.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 FUSC PF04632.12 CDJ60492.1 - 1.9 6.9 4.5 2.4 6.6 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4472 PF14739.6 CDJ60492.1 - 2.7 8.8 18.3 1 10.1 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) COQ7 PF03232.13 CDJ60492.1 - 2.7 7.7 8.5 5.9 6.6 8.5 1.9 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Atg14 PF10186.9 CDJ60492.1 - 3.2 6.8 17.4 4 6.4 17.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 CDJ60492.1 - 3.2 6.3 18.5 6.7 5.2 18.5 1.4 1 1 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 CDJ60492.1 - 3.8 5.9 16.9 28 3.0 16.5 1.8 1 1 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 CDJ60492.1 - 5 4.9 9.8 6.7 4.5 9.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 CDJ60492.1 - 5 7.2 20.4 10 6.2 20.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 CDJ60492.1 - 5.5 6.5 13.0 6.4 6.3 11.8 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TMPIT PF07851.13 CDJ60492.1 - 9.6 5.3 10.0 15 4.7 10.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein Kinesin PF00225.23 CDJ60493.1 - 3.8e-90 302.2 0.1 5.8e-90 301.6 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ60493.1 - 4.8e-23 81.7 0.0 1.2e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF1922 PF09082.10 CDJ60493.1 - 0.029 14.7 0.5 0.1 12.9 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Cep57_MT_bd PF06657.13 CDJ60493.1 - 0.18 12.3 2.9 0.61 10.6 0.2 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SecA_DEAD PF07517.14 CDJ60493.1 - 0.23 10.7 1.3 0.77 9.0 0.5 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_16 PF13191.6 CDJ60493.1 - 2.3 8.6 5.6 2.4 8.5 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain TIM PF00121.18 CDJ60494.1 - 1.2e-88 296.6 0.4 1.4e-88 296.4 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1802 PF08819.11 CDJ60494.1 - 0.054 13.3 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) MS_channel PF00924.18 CDJ60495.1 - 1.1e-12 48.0 2.4 1.7e-11 44.1 2.3 2.2 1 1 1 2 2 2 2 Mechanosensitive ion channel DUF908 PF06012.12 CDJ60496.1 - 2.5e-24 86.4 0.1 2.5e-24 86.4 0.1 22.6 17 9 1 20 20 20 1 Domain of Unknown Function (DUF908) UBM PF14377.6 CDJ60496.1 - 2.5e-15 55.3 22.6 6e-10 38.2 2.3 7.9 3 1 1 4 4 4 2 Ubiquitin binding region UBA PF00627.31 CDJ60496.1 - 4.3e-10 39.3 0.3 1.6e-09 37.4 0.3 2.1 1 0 0 1 1 1 1 UBA/TS-N domain DUF913 PF06025.12 CDJ60496.1 - 0.0003 19.9 0.0 4.9e-06 25.8 0.0 20.6 17 6 2 21 21 21 1 Domain of Unknown Function (DUF913) ORC6 PF05460.13 CDJ60496.1 - 0.00032 20.1 2.5 0.00032 20.1 2.5 17.2 17 2 2 19 19 19 1 Origin recognition complex subunit 6 (ORC6) BUD22 PF09073.10 CDJ60496.1 - 0.0098 15.3 0.1 0.0098 15.3 0.1 21.3 17 6 2 21 21 21 3 BUD22 Imm25 PF15564.6 CDJ60496.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 25 Sporozoite_P67 PF05642.11 CDJ60496.1 - 0.26 9.3 0.0 0.26 9.3 0.0 20.1 12 6 4 17 17 17 0 Sporozoite P67 surface antigen SDA1 PF05285.12 CDJ60496.1 - 0.28 10.6 0.0 0.28 10.6 0.0 17.1 14 5 1 15 15 15 0 SDA1 CCDC24 PF15669.5 CDJ60496.1 - 1.2 8.9 0.0 1.2 8.9 0.0 22.2 22 6 2 24 24 24 0 Coiled-coil domain-containing protein 24 family Plasmodium_Vir PF05795.11 CDJ60498.1 - 0.0035 16.8 3.7 0.0035 16.8 3.7 4.3 2 1 1 3 3 3 1 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 CDJ60499.1 - 0.013 13.5 0.2 0.029 12.3 0.2 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 CDJ60499.1 - 2.1 7.2 3.3 1.8 7.5 0.1 2.3 3 0 0 3 3 3 0 Ceramide synthase regulator Mito_carr PF00153.27 CDJ60500.1 - 4.2e-41 138.8 0.8 5.2e-16 58.3 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein DNA_pol_B_exo1 PF03104.19 CDJ60501.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain ArsA_ATPase PF02374.15 CDJ60502.1 - 7.4e-76 255.2 18.5 8e-57 192.7 0.0 5.3 4 1 2 6 6 6 3 Anion-transporting ATPase CbiA PF01656.23 CDJ60502.1 - 3.6e-11 43.2 0.2 6.7e-10 39.1 0.2 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDJ60502.1 - 1.6e-10 41.2 0.0 4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 CDJ60502.1 - 3.3e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CDJ60502.1 - 0.00021 20.8 0.7 0.00091 18.7 0.1 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase DUF1645 PF07816.11 CDJ60502.1 - 0.00021 21.9 2.5 0.00021 21.9 2.5 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1645) DUF2722 PF10846.8 CDJ60502.1 - 0.0017 17.4 24.9 0.0037 16.3 1.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Med25_VWA PF11265.8 CDJ60502.1 - 0.026 14.4 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A NB-ARC PF00931.22 CDJ60502.1 - 0.05 12.8 0.0 0.05 12.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 CDJ60502.1 - 0.08 12.7 6.7 1.8 8.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain MecA PF05389.12 CDJ60502.1 - 0.14 11.8 5.6 2.4 7.8 0.7 2.7 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) PTPlike_phytase PF14566.6 CDJ60502.1 - 0.2 11.8 3.3 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Inositol hexakisphosphate MipZ PF09140.11 CDJ60502.1 - 0.7 9.1 4.7 5 6.3 0.1 2.4 2 0 0 2 2 2 0 ATPase MipZ WASH-7_C PF14746.6 CDJ60502.1 - 1.7 8.3 11.7 1.2 8.8 2.3 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal SARAF PF06682.12 CDJ60502.1 - 2.7 7.5 14.9 1.9 8.0 1.3 3.2 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Ctr PF04145.15 CDJ60502.1 - 4.9 7.8 6.9 53 4.4 0.2 3.4 3 0 0 3 3 3 0 Ctr copper transporter family RLL PF10036.9 CDJ60502.1 - 5 6.9 28.8 1.1 9.0 11.8 2.8 2 1 1 3 3 3 0 RNA transcription, translation and transport factor protein HSP20 PF00011.21 CDJ60504.1 - 1.5e-18 66.8 0.0 2.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDJ60504.1 - 5.8e-06 25.8 0.0 9.6e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CODH_A_N PF18537.1 CDJ60504.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF365 PF04033.12 CDJ60504.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Kinesin PF00225.23 CDJ60505.1 - 6.7e-24 84.4 5.5 9.3e-17 60.9 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ60505.1 - 5.4e-06 26.4 0.0 5.4e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding SID-1_RNA_chan PF13965.6 CDJ60505.1 - 8.4 4.7 5.5 12 4.1 5.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SOG2 PF10428.9 CDJ60506.1 - 0.37 9.9 44.7 0.43 9.7 44.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein XRN_N PF03159.18 CDJ60508.1 - 2e-47 161.7 11.3 7.9e-41 140.1 0.0 3.5 3 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDJ60508.1 - 1.2e-43 149.8 0.2 2.4e-27 96.0 1.2 4.8 5 0 0 5 5 5 3 Xrn1 helical domain DUF2076 PF09849.9 CDJ60508.1 - 0.003 17.7 9.1 0.003 17.7 9.1 4.1 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_U57 PF05582.12 CDJ60508.1 - 0.52 9.5 3.9 4.5 6.4 3.7 2.2 2 0 0 2 2 2 0 YabG peptidase U57 RNA_pol_Rpc4 PF05132.14 CDJ60508.1 - 1.1 9.7 22.0 3.8 7.9 0.4 3.9 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF4050 PF13259.6 CDJ60508.1 - 1.5 9.1 28.3 0.15 12.3 4.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) AAR2 PF05282.11 CDJ60508.1 - 4.2 6.7 9.7 1.3 8.3 2.9 2.6 3 0 0 3 3 3 0 AAR2 protein Orf78 PF06024.12 CDJ60508.1 - 6 7.2 8.0 59 4.0 0.0 3.2 2 0 0 2 2 2 0 Orf78 (ac78) Aldo_ket_red PF00248.21 CDJ60509.1 - 9.1e-47 159.7 0.0 6.8e-44 150.2 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Prot_ATP_ID_OB PF16450.5 CDJ60510.1 - 2e-09 37.3 0.1 3.1e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain Prot_ATP_OB_N PF17758.1 CDJ60510.1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Med4 PF10018.9 CDJ60510.1 - 0.024 14.3 0.3 0.029 14.1 0.3 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ABC_tran PF00005.27 CDJ60511.1 - 1.2e-17 64.7 4.7 4.4e-13 49.9 0.0 4.3 4 0 0 4 4 4 2 ABC transporter ABC_membrane PF00664.23 CDJ60511.1 - 4.9e-12 46.1 12.4 7.4e-12 45.5 0.7 3.3 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_16 PF13191.6 CDJ60511.1 - 0.00044 20.7 0.0 0.00044 20.7 0.0 3.2 3 1 0 3 3 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ60511.1 - 0.00055 19.6 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TFIIA PF03153.13 CDJ60511.1 - 0.0015 18.6 21.1 0.0015 18.6 21.1 3.3 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 CDJ60511.1 - 0.0027 18.1 0.0 0.013 15.9 0.0 2.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CDJ60511.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CDJ60511.1 - 0.0075 16.8 0.5 0.037 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CDJ60511.1 - 0.0079 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.6 CDJ60511.1 - 0.014 15.0 0.1 0.044 13.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain MID_MedPIWI PF18296.1 CDJ60511.1 - 0.014 15.2 7.2 0.93 9.2 1.2 2.6 2 0 0 2 2 2 0 MID domain of medPIWI T2SSE PF00437.20 CDJ60511.1 - 0.016 14.3 0.0 0.043 12.9 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDJ60511.1 - 0.019 15.2 0.0 0.019 15.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 CDJ60511.1 - 0.024 15.0 0.3 0.1 12.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 CDJ60511.1 - 0.031 13.6 0.5 2 7.8 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CDJ60511.1 - 0.035 14.0 0.1 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ctr PF04145.15 CDJ60511.1 - 0.096 13.3 8.8 7.6 7.2 1.6 4.2 3 0 0 3 3 3 0 Ctr copper transporter family CW_binding_2 PF04122.12 CDJ60511.1 - 0.11 13.1 5.6 2 9.1 1.6 3.0 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 AAA_22 PF13401.6 CDJ60511.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain HA2 PF04408.23 CDJ60511.1 - 0.12 12.7 7.6 12 6.3 0.0 4.0 3 0 0 3 3 3 0 Helicase associated domain (HA2) AAA_5 PF07728.14 CDJ60511.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L6e PF01159.19 CDJ60511.1 - 0.14 12.7 0.1 0.14 12.7 0.1 3.7 4 0 0 4 4 2 0 Ribosomal protein L6e TsaE PF02367.17 CDJ60511.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CDJ60511.1 - 0.17 11.2 0.8 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 KaiC ATG22 PF11700.8 CDJ60511.1 - 0.17 10.5 6.7 3.5 6.1 1.6 3.3 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like AAA_11 PF13086.6 CDJ60511.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.4 4 1 0 4 4 4 0 AAA domain PIP5K PF01504.18 CDJ60511.1 - 0.45 9.7 3.9 0.36 10.0 0.9 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase MecA PF05389.12 CDJ60511.1 - 0.6 9.7 9.8 0.35 10.5 2.1 3.2 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF2722 PF10846.8 CDJ60511.1 - 0.65 8.9 43.2 0.013 14.5 24.3 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 CDJ60511.1 - 0.66 11.0 26.7 0.031 15.2 4.6 5.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 CDJ60511.1 - 0.77 10.2 0.0 0.77 10.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain Med15 PF09606.10 CDJ60511.1 - 0.8 8.3 35.6 0.24 10.0 22.2 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Folliculin PF11704.8 CDJ60511.1 - 3.7 7.4 8.5 2 8.3 2.7 2.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport OATP PF03137.20 CDJ60511.1 - 9.7 4.3 6.4 6.8 4.9 1.8 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Vps51 PF08700.11 CDJ60512.1 - 7.7e-20 70.8 0.7 2.5e-19 69.1 0.1 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CDJ60512.1 - 2.6e-07 30.8 0.7 9.6e-07 29.0 0.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 CDJ60512.1 - 2e-05 24.5 0.9 5.5e-05 23.0 0.9 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.9 CDJ60512.1 - 3.2e-05 24.1 2.5 5.1e-05 23.4 1.1 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Dor1 PF04124.12 CDJ60512.1 - 8e-05 21.5 6.8 0.00015 20.6 6.8 1.4 1 0 0 1 1 1 1 Dor1-like family Laminin_II PF06009.12 CDJ60512.1 - 0.0095 16.0 0.3 0.033 14.2 0.3 1.9 1 0 0 1 1 1 1 Laminin Domain II Vps54_N PF10475.9 CDJ60512.1 - 0.017 14.4 0.5 0.034 13.4 0.5 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF948 PF06103.11 CDJ60512.1 - 0.08 13.2 5.0 0.14 12.4 1.8 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_15 PF13429.6 CDJ60513.1 - 0.0039 16.4 0.7 0.0065 15.7 0.7 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat YebO PF13974.6 CDJ60513.1 - 0.94 9.6 4.7 3.2 7.9 4.7 1.9 1 0 0 1 1 1 0 YebO-like protein Pkinase PF00069.25 CDJ60514.1 - 9.6e-37 126.8 0.0 1.3e-29 103.4 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60514.1 - 4.2e-22 78.7 0.0 4.6e-18 65.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CDJ60514.1 - 0.028 14.4 0.0 0.24 11.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ60514.1 - 0.077 11.8 0.1 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_60s PF00428.19 CDJ60515.1 - 1.6 9.4 10.7 0.31 11.6 5.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3138 PF11336.8 CDJ60515.1 - 3.5 6.1 8.4 6.3 5.3 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Glycos_transf_2 PF00535.26 CDJ60516.1 - 2e-19 70.1 0.0 4e-19 69.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CDJ60516.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDJ60516.1 - 0.00021 20.9 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LRR_8 PF13855.6 CDJ60517.1 - 4.1e-05 23.3 5.9 0.043 13.6 0.9 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDJ60517.1 - 0.028 14.8 6.3 0.83 10.2 1.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Citrate_synt PF00285.21 CDJ60518.1 - 1e-10 41.2 0.1 1.9e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain Macoilin PF09726.9 CDJ60519.1 - 6.9 5.1 11.1 9.8 4.6 11.1 1.2 1 0 0 1 1 1 0 Macoilin family Shadoo PF14999.6 CDJ60522.1 - 0.004 17.2 3.7 0.011 15.8 3.7 1.7 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Spem1 PF15670.5 CDJ60522.1 - 0.016 14.8 4.3 0.023 14.3 4.3 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 CCDC106 PF15794.5 CDJ60522.1 - 0.099 12.3 9.0 0.14 11.8 9.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Dehydrin PF00257.19 CDJ60522.1 - 0.32 11.5 20.1 0.12 12.9 12.8 2.1 2 0 0 2 2 2 0 Dehydrin Transformer PF06495.11 CDJ60522.1 - 0.62 10.1 15.5 1.2 9.2 15.5 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein NPR3 PF03666.13 CDJ60522.1 - 1.1 8.0 7.5 1.3 7.7 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3827 PF12877.7 CDJ60522.1 - 1.7 7.0 8.2 2.1 6.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Presenilin PF01080.17 CDJ60522.1 - 1.7 7.3 4.1 2.2 7.0 4.1 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDJ60522.1 - 2 7.2 8.4 2.4 6.9 8.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HSP70 PF00012.20 CDJ60523.1 - 4.8e-208 692.2 0.5 5.9e-208 691.9 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDJ60523.1 - 4.4e-16 58.6 1.2 4.6e-14 52.0 0.3 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDJ60523.1 - 0.0016 18.9 0.1 4.7 7.7 0.0 3.1 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 CDJ60523.1 - 0.032 13.9 0.0 0.081 12.6 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 CDJ60524.1 - 7e-44 150.0 1.8 9.1e-44 149.6 1.8 1.1 1 0 0 1 1 1 1 Hsp70 protein HBS1_N PF08938.10 CDJ60524.1 - 0.0017 18.6 2.6 0.0029 17.9 2.6 1.4 1 0 0 1 1 1 1 HBS1 N-terminus Big_1 PF02369.16 CDJ60524.1 - 0.17 11.9 6.0 2 8.5 1.4 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 1) MRNIP PF15749.5 CDJ60524.1 - 4.1 8.2 8.1 1.1 10.0 0.2 2.1 1 1 1 2 2 2 0 MRN-interacting protein CP12 PF02672.15 CDJ60524.1 - 4.6 8.1 6.9 26 5.6 3.8 2.2 1 1 1 2 2 2 0 CP12 domain Pkinase PF00069.25 CDJ60525.1 - 1.3e-38 132.9 0.1 1.6e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60525.1 - 1e-20 74.2 0.1 1.2e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDJ60525.1 - 2.1e-05 24.0 0.2 5.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ60525.1 - 0.0015 18.5 0.0 0.59 10.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ60525.1 - 0.026 13.3 0.1 0.047 12.5 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CDJ60525.1 - 0.029 14.0 0.0 0.062 12.9 0.0 1.6 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Integrin_alpha PF00357.20 CDJ60525.1 - 0.2 11.7 0.1 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region RNase_HII PF01351.18 CDJ60526.1 - 4.5e-48 163.7 0.0 2.8e-44 151.3 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII HNHc_6 PF16784.5 CDJ60526.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative HNHc nuclease PASTA PF03793.19 CDJ60526.1 - 0.11 12.4 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 PASTA domain DUF1874 PF08960.10 CDJ60526.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) Aminotran_4 PF01063.19 CDJ60527.1 - 2.1e-15 57.2 0.1 8.7e-15 55.2 0.1 2.0 1 1 1 2 2 2 1 Amino-transferase class IV Spt20 PF12090.8 CDJ60527.1 - 0.0023 17.6 33.7 0.05 13.2 13.4 2.2 2 0 0 2 2 2 2 Spt20 family TFIIA PF03153.13 CDJ60527.1 - 0.015 15.3 33.3 0.12 12.3 13.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 CDJ60527.1 - 0.062 13.4 10.8 0.15 12.2 1.8 2.3 2 0 0 2 2 2 0 DDHD domain BORG_CEP PF14957.6 CDJ60527.1 - 1.5 10.0 8.0 1.3 10.2 0.5 2.3 2 0 0 2 2 2 0 Cdc42 effector Neur_chan_memb PF02932.16 CDJ60527.1 - 1.6 8.7 7.0 5.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 CDJ60527.1 - 4.3 7.6 8.8 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Zip PF02535.22 CDJ60527.1 - 7.9 5.6 7.3 5.1 6.2 1.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter TM231 PF10149.9 CDJ60528.1 - 1.3 8.3 7.7 2.4 7.4 7.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 231 GTP_EFTU PF00009.27 CDJ60530.1 - 7.1e-56 188.8 0.0 1.8e-55 187.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDJ60530.1 - 1.2e-30 105.4 0.0 2.3e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDJ60530.1 - 5.3e-12 45.9 0.0 1.5e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CDJ60530.1 - 1.7e-07 31.0 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 CDJ60530.1 - 3e-06 27.1 0.1 5.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 CDJ60530.1 - 0.016 15.7 0.0 0.37 11.3 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain DNA_pol3_tau_5 PF12170.8 CDJ60530.1 - 0.016 15.2 0.4 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha Methyltr_RsmB-F PF01189.17 CDJ60531.1 - 1.4e-17 64.1 1.1 2.8e-08 33.7 0.1 4.7 5 0 0 5 5 5 2 16S rRNA methyltransferase RsmB/F TFIIA PF03153.13 CDJ60531.1 - 0.0084 16.1 8.6 0.012 15.6 7.5 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CDJ60531.1 - 1.2 9.5 6.7 0.41 11.0 2.0 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 CDJ60531.1 - 8.5 5.0 5.6 14 4.3 5.6 1.2 1 0 0 1 1 1 0 Presenilin MIF4G PF02854.19 CDJ60535.1 - 4.9e-18 65.5 1.1 1e-17 64.5 0.1 1.9 2 0 0 2 2 2 1 MIF4G domain Gp_dh_N PF00044.24 CDJ60535.1 - 5.9e-06 26.6 0.7 1.4e-05 25.4 0.7 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RAP1 PF07218.11 CDJ60535.1 - 3.9 5.7 7.8 8 4.6 7.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2098 PF09871.9 CDJ60535.1 - 7.4 7.0 7.2 8.4 6.8 0.1 3.7 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2098) Peptidase_C48 PF02902.19 CDJ60537.1 - 2.7e-14 53.5 0.0 6.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DDHD PF02862.17 CDJ60537.1 - 0.075 13.2 11.5 0.76 9.9 2.5 3.4 4 0 0 4 4 4 0 DDHD domain MAAL_C PF07476.11 CDJ60537.1 - 0.096 11.8 0.3 0.18 10.9 0.3 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus TCP PF03634.13 CDJ60537.1 - 2.2 8.8 25.0 5.8 7.5 9.9 3.9 4 0 0 4 4 4 0 TCP family transcription factor Peptidase_S64 PF08192.11 CDJ60537.1 - 4.9 5.5 9.5 5 5.5 4.2 2.3 2 0 0 2 2 2 0 Peptidase family S64 Pkinase PF00069.25 CDJ60538.1 - 9.4e-27 94.0 0.0 3.3e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60538.1 - 6e-08 32.3 0.0 0.00037 19.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3402 PF11882.8 CDJ60538.1 - 0.0014 17.8 1.6 0.0014 17.8 1.6 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3402) EPL1 PF10513.9 CDJ60538.1 - 0.17 12.3 12.2 0.25 11.7 1.3 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF2722 PF10846.8 CDJ60539.1 - 2.9e-06 26.5 19.6 1.8e-05 23.9 10.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ60539.1 - 0.00022 21.3 35.6 0.0011 19.1 14.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ60539.1 - 0.00041 19.2 11.5 0.00041 19.2 11.5 3.0 3 0 0 3 3 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 CDJ60539.1 - 0.0018 18.3 4.0 0.0018 18.3 4.0 2.4 3 0 0 3 3 2 1 Suppressor of forked protein (Suf) RLL PF10036.9 CDJ60539.1 - 0.0032 17.4 1.6 0.0032 17.4 1.6 2.2 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein MecA PF05389.12 CDJ60539.1 - 0.0082 15.8 4.8 0.092 12.4 0.8 2.1 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) Tsg PF04668.12 CDJ60539.1 - 0.0086 16.8 2.4 0.0086 16.8 2.4 2.3 2 0 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region OATP PF03137.20 CDJ60539.1 - 0.03 12.6 3.4 0.049 11.9 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Mlh1_C PF16413.5 CDJ60539.1 - 0.073 12.4 6.6 0.06 12.7 0.7 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus eIF-3_zeta PF05091.12 CDJ60539.1 - 0.073 12.0 13.1 0.017 14.1 4.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 CDJ60539.1 - 0.075 13.4 11.0 1.2 9.5 6.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like TERB2 PF15101.6 CDJ60539.1 - 0.082 13.0 17.2 0.39 10.7 8.7 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF913 PF06025.12 CDJ60539.1 - 0.12 11.4 2.4 0.11 11.5 0.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Peroxin-13_N PF04088.13 CDJ60539.1 - 0.12 12.7 3.6 0.64 10.3 0.3 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Het-C PF07217.11 CDJ60539.1 - 0.13 10.8 6.7 0.75 8.3 0.5 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C RR_TM4-6 PF06459.12 CDJ60539.1 - 0.17 11.7 7.2 0.058 13.2 0.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ60539.1 - 0.18 11.6 8.0 0.18 11.6 1.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Eapp_C PF10238.9 CDJ60539.1 - 0.21 11.7 10.5 0.12 12.5 4.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Connexin PF00029.19 CDJ60539.1 - 0.25 11.1 4.2 0.19 11.4 0.4 2.0 2 0 0 2 2 2 0 Connexin SAE2 PF08573.10 CDJ60539.1 - 0.3 12.2 11.8 4.3 8.5 0.9 2.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus SpoIIP PF07454.11 CDJ60539.1 - 0.35 10.3 12.1 1.3 8.4 7.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) GET2 PF08690.10 CDJ60539.1 - 0.61 9.7 12.4 0.019 14.7 2.0 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4175 PF13779.6 CDJ60539.1 - 0.76 7.6 32.4 0.059 11.3 16.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Rxt3 PF08642.10 CDJ60539.1 - 1.1 10.1 4.2 1.6 9.5 0.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF3371 PF11851.8 CDJ60539.1 - 1.3 10.1 16.1 0.93 10.6 5.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Afi1 PF07792.12 CDJ60539.1 - 1.4 9.4 12.4 0.18 12.3 4.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ANAPC_CDC26 PF10471.9 CDJ60539.1 - 1.5 9.7 40.0 0.33 11.8 19.6 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 ORC_WH_C PF18137.1 CDJ60539.1 - 1.5 8.9 10.2 1.2 9.2 4.5 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RPA43_OB PF17875.1 CDJ60539.1 - 1.6 9.4 7.0 0.53 10.9 1.5 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I BRF1 PF07741.13 CDJ60539.1 - 1.7 9.0 12.7 5.4 7.4 5.7 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Tim54 PF11711.8 CDJ60539.1 - 1.8 7.3 9.3 5.6 5.6 5.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3464 PF11947.8 CDJ60539.1 - 1.8 8.3 12.8 9.4 6.0 8.8 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF775 PF05603.12 CDJ60539.1 - 1.9 8.0 18.7 0.12 11.8 7.5 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF775) Senescence_reg PF04520.13 CDJ60539.1 - 2.3 9.0 13.9 2.8 8.7 0.1 3.2 3 0 0 3 3 3 0 Senescence regulator Spt20 PF12090.8 CDJ60539.1 - 3.3 7.3 54.6 2.7 7.5 34.5 2.3 2 0 0 2 2 2 0 Spt20 family DUF2126 PF09899.9 CDJ60539.1 - 3.3 5.7 6.3 0.28 9.2 0.5 1.8 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF702 PF05142.12 CDJ60539.1 - 3.9 7.9 14.0 5.3 7.5 6.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) ARF7EP_C PF14949.6 CDJ60539.1 - 4.5 7.9 12.7 0.46 11.1 5.1 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus FAM176 PF14851.6 CDJ60539.1 - 5.1 6.8 6.4 4.2 7.0 2.3 2.1 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.6 CDJ60539.1 - 5.1 7.5 10.1 2.2 8.6 3.7 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PH_4 PF15404.6 CDJ60539.1 - 6.6 6.5 10.5 0.8 9.5 3.7 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain V_ATPase_I PF01496.19 CDJ60539.1 - 6.7 4.5 10.9 0.46 8.3 3.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3381 PF11861.8 CDJ60539.1 - 7.1 6.4 18.0 8.5 6.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF868 PF05910.12 CDJ60539.1 - 8.6 5.9 9.7 0.25 10.9 2.8 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF868) CLN3 PF02487.17 CDJ60539.1 - 9.3 5.2 7.3 1.9 7.4 2.1 1.9 2 0 0 2 2 2 0 CLN3 protein Pkinase PF00069.25 CDJ60540.1 - 4.1e-21 75.5 0.0 1.6e-14 54.0 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain RskA PF10099.9 CDJ60540.1 - 0.0015 18.9 2.1 0.0015 18.9 2.1 6.7 3 1 3 6 6 6 1 Anti-sigma-K factor rskA LRR_8 PF13855.6 CDJ60541.1 - 5.9e-05 22.8 0.1 0.0001 22.0 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat FHIPEP PF00771.20 CDJ60541.1 - 0.00032 19.3 2.1 0.00041 19.0 2.1 1.1 1 0 0 1 1 1 1 FHIPEP family LRR_4 PF12799.7 CDJ60541.1 - 0.0033 17.8 0.3 0.0064 16.9 0.3 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LigT_PEase PF02834.16 CDJ60541.1 - 0.063 13.5 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 LigT like Phosphoesterase DUF4484 PF14831.6 CDJ60541.1 - 0.18 11.8 4.2 0.27 11.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) PAT1 PF09770.9 CDJ60541.1 - 0.24 9.6 13.7 0.3 9.3 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_9 PF14580.6 CDJ60541.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeat PEX11 PF05648.14 CDJ60541.1 - 1.6 8.2 5.4 3.3 7.1 5.4 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Ferlin_C PF16165.5 CDJ60541.1 - 1.8 8.5 6.4 0.17 11.8 0.7 2.2 2 0 0 2 2 2 0 Ferlin C-terminus LAP1C PF05609.12 CDJ60541.1 - 2.4 7.2 13.5 3.2 6.7 13.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 CDJ60541.1 - 2.6 7.3 8.3 3.3 7.0 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 CDJ60541.1 - 2.7 7.7 8.5 0.14 11.8 2.4 1.9 2 0 0 2 2 2 0 FAM176 family PA26 PF04636.13 CDJ60541.1 - 3.6 6.4 6.8 4.9 6.0 6.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4551 PF15087.6 CDJ60541.1 - 5.3 5.8 14.0 7.4 5.3 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RNA_pol_Rpo13 PF12136.8 CDJ60543.1 - 9.9 6.2 7.8 7.3 6.6 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain BPL_N PF09825.9 CDJ60544.1 - 0.49 9.4 15.9 0.55 9.3 15.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PAT1 PF09770.9 CDJ60544.1 - 2.8 6.1 49.2 3.2 5.9 49.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MRP-S26 PF14943.6 CDJ60544.1 - 6.9 6.6 31.5 13 5.6 31.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 ACDC PF14733.6 CDJ60546.1 - 3e-14 53.1 2.0 3.2e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ60546.1 - 2.5e-05 24.4 0.4 2.5e-05 24.4 0.4 2.9 3 0 0 3 3 3 1 AP2 domain DUF4025 PF13217.6 CDJ60547.1 - 0.086 12.7 0.0 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4025) DUF4046 PF13255.6 CDJ60547.1 - 0.17 12.4 0.0 28 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) RIB43A PF05914.12 CDJ60549.1 - 0.0011 17.9 1.6 0.0019 17.0 1.6 1.3 1 0 0 1 1 1 1 RIB43A FAM27 PF15832.5 CDJ60549.1 - 0.052 14.1 1.6 0.11 13.0 1.6 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family Fer4_14 PF13394.6 CDJ60549.1 - 0.11 12.7 0.0 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Synaptobrevin PF00957.21 CDJ60551.1 - 3.3e-28 97.3 2.8 4.6e-28 96.9 2.8 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDJ60551.1 - 2e-19 69.4 0.1 3.2e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Corona_S2 PF01601.16 CDJ60551.1 - 0.0088 14.6 0.0 0.0088 14.6 0.0 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Baculo_F PF12259.8 CDJ60551.1 - 0.056 12.0 0.1 0.072 11.6 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein Herpes_teg_N PF04843.12 CDJ60551.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region MCU PF04678.13 CDJ60551.1 - 0.16 12.1 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4224 PF13986.6 CDJ60552.1 - 0.11 12.4 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Mak10 PF04112.13 CDJ60552.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Kazal_2 PF07648.15 CDJ60553.1 - 2.8e-08 33.7 9.3 3.3e-08 33.5 2.1 3.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDJ60553.1 - 5.1e-05 23.2 4.8 0.00011 22.1 0.5 3.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain STI1 PF17830.1 CDJ60554.1 - 0.00012 21.9 0.2 0.00017 21.4 0.2 1.2 1 0 0 1 1 1 1 STI1 domain DUF817 PF05675.12 CDJ60555.1 - 0.012 15.3 0.6 0.015 14.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF817) ASH PF15780.5 CDJ60556.1 - 0.00027 21.1 5.6 0.0048 17.1 0.2 4.5 4 1 1 5 5 5 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDJ60556.1 - 0.00097 19.3 2.2 0.046 13.9 0.1 4.0 4 0 0 4 4 4 1 Flagellar-associated PapD-like Peptidase_S9 PF00326.21 CDJ60557.1 - 4.7e-15 55.6 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ60557.1 - 0.011 15.1 0.0 0.58 9.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ60557.1 - 0.028 14.0 0.1 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 CDJ60557.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4110 PF13422.6 CDJ60558.1 - 0.04 14.0 0.3 0.04 14.0 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Surp PF01805.20 CDJ60559.1 - 2.2e-37 126.8 1.1 7.1e-18 64.4 0.0 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 CDJ60559.1 - 4.6e-16 59.3 4.9 4.6e-16 59.3 4.9 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein DUF1682 PF07946.14 CDJ60559.1 - 0.00038 19.8 1.2 0.00038 19.8 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) RRP36 PF06102.12 CDJ60559.1 - 0.036 14.0 7.0 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 TNT PF14021.6 CDJ60559.1 - 0.071 13.7 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Toprim_Crpt PF13342.6 CDJ60559.1 - 0.2 11.6 0.5 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Peptidase_S30 PF01577.16 CDJ60560.1 - 0.59 9.7 20.1 0.7 9.5 20.1 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease HGTP_anticodon2 PF12745.7 CDJ60560.1 - 1.8 8.0 20.2 2.2 7.7 20.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs VIR_N PF15912.5 CDJ60560.1 - 4.9 6.7 15.3 5.8 6.4 15.3 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal TFIIA PF03153.13 CDJ60560.1 - 5.7 6.8 42.0 6.6 6.6 42.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CDJ60560.1 - 6.7 7.4 27.3 9.1 6.9 27.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2828 PF11443.8 CDJ60560.1 - 7.1 4.6 17.5 8.1 4.4 17.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CDJ60560.1 - 8.5 5.0 25.0 9.4 4.9 25.0 1.0 1 0 0 1 1 1 0 Presenilin zf-MYND PF01753.18 CDJ60561.1 - 0.00011 22.2 3.3 0.00011 22.2 3.3 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CDJ60561.1 - 0.0092 16.1 1.0 0.0092 16.1 1.0 3.0 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 LBP_M PF17385.2 CDJ60561.1 - 0.1 12.1 1.6 0.21 11.1 1.6 1.5 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain CheY-binding PF09078.11 CDJ60561.1 - 0.76 9.9 4.0 2.6 8.2 4.0 1.9 1 0 0 1 1 1 0 CheY binding RRM_1 PF00076.22 CDJ60564.1 - 4.8e-05 23.1 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Activator_LAG-3 PF11498.8 CDJ60564.1 - 0.00074 18.6 72.4 0.01 14.9 14.1 4.4 4 0 0 4 4 4 4 Transcriptional activator LAG-3 Anticodon_1 PF08264.13 CDJ60566.1 - 6.2e-14 52.2 0.8 1.3e-10 41.4 0.4 2.6 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CDJ60566.1 - 2e-11 42.9 14.1 0.0001 20.7 0.1 4.7 5 0 0 5 5 5 3 tRNA synthetases class I (I, L, M and V) P53_C PF11619.8 CDJ60566.1 - 3.9e-05 23.6 1.3 8.1e-05 22.6 0.3 2.0 2 0 0 2 2 2 1 Transcription factor P53 - C terminal domain tRNA-synt_1g PF09334.11 CDJ60566.1 - 6.2e-05 21.9 14.2 0.0016 17.3 0.2 3.6 4 0 0 4 4 4 2 tRNA synthetases class I (M) BUD22 PF09073.10 CDJ60566.1 - 0.0046 16.4 46.1 0.084 12.2 8.0 4.7 4 0 0 4 4 4 4 BUD22 DUF2207 PF09972.9 CDJ60566.1 - 0.11 11.2 0.0 0.28 9.9 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LMBR1 PF04791.16 CDJ60566.1 - 3.3 6.5 4.2 5.6 5.8 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HCO3_cotransp PF00955.21 CDJ60566.1 - 3.8 6.2 4.7 9.6 4.9 4.7 1.6 1 0 0 1 1 1 0 HCO3- transporter family SID-1_RNA_chan PF13965.6 CDJ60566.1 - 6.3 5.1 7.8 4.7 5.5 3.1 2.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Ketoacyl-synt_C PF02801.22 CDJ60567.1 - 1.4e-37 128.3 0.3 2.8e-37 127.3 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CDJ60567.1 - 1.2e-35 123.3 1.9 6.6e-35 120.9 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CDJ60567.1 - 0.00077 18.9 1.5 0.0035 16.7 0.8 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CDJ60567.1 - 0.14 12.0 4.7 5.3 7.0 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CactinC_cactus PF09732.9 CDJ60568.1 - 5.6e-54 181.4 9.6 5.6e-54 181.4 9.6 1.6 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CDJ60568.1 - 3.3e-46 157.5 1.7 3.3e-46 157.5 1.7 2.7 2 0 0 2 2 2 1 Conserved mid region of cactin Spt20 PF12090.8 CDJ60569.1 - 0.033 13.8 2.1 0.034 13.8 2.1 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ60569.1 - 1.6 7.6 14.7 2 7.3 14.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNA_pol_Rbc25 PF08292.12 CDJ60570.1 - 2.6e-15 56.8 0.0 7.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDJ60570.1 - 1.2e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F5_F8_type_C PF00754.25 CDJ60570.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain RskA PF10099.9 CDJ60570.1 - 0.13 12.6 16.2 0.19 12.0 16.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA S1 PF00575.23 CDJ60570.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 2 0 0 2 2 2 0 S1 RNA binding domain Tic110 PF16940.5 CDJ60570.1 - 1.8 6.9 11.5 2.2 6.7 11.5 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Spt20 PF12090.8 CDJ60571.1 - 0.00011 21.9 14.7 0.00011 21.9 14.7 8.9 5 2 4 9 9 9 2 Spt20 family DUF755 PF05501.11 CDJ60571.1 - 0.0022 18.3 17.1 0.0022 18.3 17.1 11.1 9 3 1 10 10 10 1 Domain of unknown function (DUF755) GTP_EFTU PF00009.27 CDJ60572.1 - 1e-39 136.1 0.0 3.5e-32 111.5 0.0 3.0 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDJ60572.1 - 5.9e-12 45.5 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CDJ60572.1 - 2.6e-07 30.5 0.3 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_C PF00679.24 CDJ60572.1 - 0.011 15.7 0.0 0.039 14.0 0.0 1.9 1 0 0 1 1 1 0 Elongation factor G C-terminus Pro-MCH PF05824.12 CDJ60572.1 - 0.029 14.3 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) MMR_HSR1 PF01926.23 CDJ60572.1 - 0.033 14.3 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ldi PF18566.1 CDJ60572.1 - 0.28 10.6 2.6 0.94 8.9 2.6 1.8 1 0 0 1 1 1 0 Linalool dehydratase/isomerase SPOUT_MTase PF02590.17 CDJ60572.1 - 1.4 8.9 6.7 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Draxin PF15550.6 CDJ60572.1 - 5 6.9 9.0 0.43 10.4 3.1 2.1 2 0 0 2 2 2 0 Draxin Actin PF00022.19 CDJ60573.1 - 3.8e-19 68.6 4.1 2.8e-18 65.7 0.0 2.9 3 1 0 3 3 3 1 Actin DUF2722 PF10846.8 CDJ60573.1 - 7.3e-05 21.9 9.2 7.3e-05 21.9 9.2 3.5 3 1 1 4 4 2 1 Protein of unknown function (DUF2722) DUF755 PF05501.11 CDJ60573.1 - 0.0022 18.2 26.4 0.0022 18.2 26.4 3.7 3 1 0 3 3 1 1 Domain of unknown function (DUF755) Pex14_N PF04695.13 CDJ60573.1 - 0.0028 18.3 1.3 0.0028 18.3 1.3 4.2 3 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 CDJ60573.1 - 0.065 13.0 0.0 0.065 13.0 0.0 2.8 2 1 0 2 2 1 0 Connexin TFIIA PF03153.13 CDJ60573.1 - 0.089 12.8 61.8 0.089 12.8 17.9 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ60573.1 - 0.79 8.6 23.9 0.051 12.6 3.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Atg14 PF10186.9 CDJ60573.1 - 0.96 8.5 27.7 0.39 9.8 12.2 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Band_3_cyto PF07565.13 CDJ60573.1 - 1.5 8.6 24.4 2.1 8.1 4.3 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Suf PF05843.14 CDJ60573.1 - 5.1 7.0 34.2 0.73 9.8 7.4 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Dala_Dala_lig_N PF01820.21 CDJ60573.1 - 7.8 7.0 6.9 13 6.3 0.7 2.8 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Exonuc_VII_L PF02601.15 CDJ60573.1 - 8.2 5.9 30.2 0.74 9.3 13.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Carb_kinase PF01256.17 CDJ60575.1 - 8.1e-25 87.7 4.0 1e-14 54.6 0.2 4.6 3 2 0 3 3 3 3 Carbohydrate kinase GET2 PF08690.10 CDJ60575.1 - 0.33 10.6 2.3 2.1 7.9 1.4 2.1 1 1 1 2 2 2 0 GET complex subunit GET2 ANAPC_CDC26 PF10471.9 CDJ60575.1 - 2 9.3 9.6 2.3 9.1 4.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CDJ60575.1 - 3.5 7.2 7.4 0.4 10.3 3.3 1.4 2 0 0 2 2 2 0 Spt20 family AP2 PF00847.20 CDJ60577.1 - 3.6e-07 30.3 2.9 3.3e-06 27.2 0.6 3.1 2 0 0 2 2 2 1 AP2 domain Glyco_transf_17 PF04724.13 CDJ60578.1 - 4.1e-18 65.5 0.3 2.9e-17 62.7 0.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 17 Epimerase PF01370.21 CDJ60579.1 - 2.9e-41 141.5 0.0 4.2e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDJ60579.1 - 5.9e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDJ60579.1 - 0.00026 20.1 0.0 0.001 18.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDJ60579.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDJ60579.1 - 0.018 14.2 0.1 0.037 13.2 0.0 1.5 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Lebercilin PF15619.6 CDJ60580.1 - 0.026 14.2 0.5 0.026 14.2 0.5 4.1 5 0 0 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease SLT_2 PF13406.6 CDJ60580.1 - 0.24 10.6 2.7 0.26 10.5 0.0 2.4 3 0 0 3 3 3 0 Transglycosylase SLT domain FapA PF03961.13 CDJ60580.1 - 0.38 9.3 16.1 0.96 8.0 6.5 2.8 3 0 0 3 3 3 0 Flagellar Assembly Protein A DUF4618 PF15397.6 CDJ60580.1 - 0.39 10.1 22.9 0.079 12.4 1.8 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) FlxA PF14282.6 CDJ60580.1 - 0.54 10.3 27.5 4.1 7.5 0.9 4.0 3 1 0 3 3 3 0 FlxA-like protein BST2 PF16716.5 CDJ60580.1 - 2.1 9.0 20.5 0.18 12.4 6.1 3.6 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 ZnuA PF01297.17 CDJ60580.1 - 2.7 7.3 5.8 0.34 10.3 1.4 1.6 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Ax_dynein_light PF10211.9 CDJ60580.1 - 3.8 7.4 26.2 0.024 14.6 10.4 3.4 4 0 0 4 4 4 0 Axonemal dynein light chain BRCT PF00533.26 CDJ60581.1 - 0.0035 17.7 0.1 0.022 15.1 0.0 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TIP49 PF06068.13 CDJ60582.1 - 2.1e-149 497.5 0.1 2.6e-149 497.2 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ60582.1 - 1.8e-19 69.6 0.1 1.2e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ60582.1 - 3.5e-06 27.5 0.1 0.043 14.3 0.1 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ60582.1 - 0.014 15.7 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLPTM1 PF05602.12 CDJ60583.1 - 7.2e-74 249.3 22.6 5.8e-61 206.8 2.4 2.2 1 1 1 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CDJ60583.1 - 2.5e-05 24.0 3.0 0.016 14.9 0.1 3.0 3 0 0 3 3 3 2 PQ loop repeat TT_ORF1 PF02956.14 CDJ60583.1 - 0.0055 15.5 7.5 0.0084 14.8 7.5 1.2 1 0 0 1 1 1 1 TT viral orf 1 DDHD PF02862.17 CDJ60583.1 - 0.013 15.7 12.2 0.11 12.7 10.1 2.3 2 0 0 2 2 2 0 DDHD domain Velvet PF11754.8 CDJ60583.1 - 0.16 11.9 11.5 0.061 13.3 6.3 2.2 2 0 0 2 2 2 0 Velvet factor BSMAP PF12280.8 CDJ60583.1 - 0.31 11.2 10.7 1.8 8.7 10.5 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein Presenilin PF01080.17 CDJ60583.1 - 0.33 9.7 23.8 0.49 9.1 18.3 2.4 2 0 0 2 2 2 0 Presenilin RNA_pol_Rpc4 PF05132.14 CDJ60583.1 - 0.35 11.3 18.0 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 UPF0242 PF06785.11 CDJ60583.1 - 0.48 10.5 24.8 0.73 9.9 20.7 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CAF1 PF04857.20 CDJ60583.1 - 1.4 8.1 10.4 2.9 7.0 10.4 1.5 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF2723 PF11028.8 CDJ60583.1 - 2 8.3 7.3 0.55 10.2 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Zip PF02535.22 CDJ60583.1 - 3.2 6.9 12.5 0.46 9.7 5.4 2.6 2 1 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CDJ60583.1 - 4.6 7.2 17.3 1.8 8.5 12.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.12 CDJ60583.1 - 5.1 6.0 14.1 1.8 7.5 8.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Exonuc_VII_L PF02601.15 CDJ60583.1 - 6.1 6.3 18.4 10 5.6 18.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RTA1 PF04479.13 CDJ60583.1 - 6.5 6.3 8.0 0.44 10.1 0.6 2.5 3 0 0 3 3 3 0 RTA1 like protein Endostatin PF06482.11 CDJ60583.1 - 7.6 5.9 20.1 2.5 7.5 16.0 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin RIFIN PF02009.16 CDJ60583.1 - 8.7 6.1 19.0 0.72 9.7 10.9 2.2 2 0 0 2 2 2 0 Rifin CPSF100_C PF13299.6 CDJ60583.1 - 9.6 6.4 19.0 1 9.5 9.5 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EIF_2_alpha PF07541.12 CDJ60584.1 - 2.9e-31 108.0 0.0 6.1e-31 106.9 0.0 1.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CDJ60584.1 - 8.3e-12 45.3 0.9 1.6e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 CDJ60584.1 - 0.069 13.8 0.2 0.2 12.3 0.2 1.8 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Phage_1_1 PF08200.11 CDJ60584.1 - 0.13 12.7 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Mob1_phocein PF03637.17 CDJ60585.1 - 4.5e-14 52.8 0.0 8.3e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Clathrin PF00637.20 CDJ60586.1 - 5.1e-09 36.1 10.6 8.5e-06 25.7 0.2 6.1 3 2 4 7 7 7 2 Region in Clathrin and VPS Nic96 PF04097.14 CDJ60586.1 - 0.0099 14.4 7.7 0.44 8.9 0.1 3.3 2 1 2 4 4 4 2 Nup93/Nic96 TPR_7 PF13176.6 CDJ60586.1 - 0.13 12.3 16.9 0.16 12.1 0.4 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60586.1 - 4.1 7.4 13.8 19 5.3 0.0 7.0 7 3 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60586.1 - 5.8 7.3 35.4 6.8 7.1 0.1 10.1 9 4 3 12 12 12 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60586.1 - 6.9 7.2 14.1 57 4.3 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat JAB PF01398.21 CDJ60587.1 - 0.003 17.5 0.0 0.0089 16.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PFU PF09070.11 CDJ60589.1 - 5.3e-23 81.4 0.1 1.1e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 CDJ60589.1 - 3.4e-12 46.2 10.4 5.7e-10 38.9 8.0 3.3 2 1 0 2 2 2 1 PUL domain WD40 PF00400.32 CDJ60589.1 - 5.5e-05 23.9 0.9 5.6 8.0 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3340 PF11818.8 CDJ60589.1 - 0.12 12.6 4.5 0.081 13.1 1.2 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Zn_ribbon_recom PF13408.6 CDJ60589.1 - 0.17 12.5 1.4 0.4 11.2 1.4 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain EphA2_TM PF14575.6 CDJ60589.1 - 0.42 11.5 1.5 1.2 10.1 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AAA_6 PF12774.7 CDJ60590.1 - 3e-145 483.3 0.2 1.3e-142 474.6 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDJ60590.1 - 2.6e-86 289.2 0.0 7.8e-86 287.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDJ60590.1 - 8.3e-83 278.1 0.5 3.4e-82 276.1 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDJ60590.1 - 3.9e-78 261.6 0.9 3.9e-78 261.6 0.9 2.7 3 0 0 3 3 2 1 ATP-binding dynein motor region DHC_N2 PF08393.13 CDJ60590.1 - 2.4e-60 204.7 6.2 1.5e-45 156.0 3.4 6.5 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CDJ60590.1 - 3.2e-55 186.5 0.1 1.5e-49 167.9 0.0 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDJ60590.1 - 1.6e-49 167.9 0.0 3.8e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDJ60590.1 - 1.7e-40 137.8 0.0 1.9e-39 134.5 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDJ60590.1 - 1.9e-27 96.2 19.0 2e-27 96.2 17.0 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CDJ60590.1 - 2.8e-21 76.0 0.1 4.3e-07 30.0 0.0 5.7 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ60590.1 - 7.6e-20 71.3 3.4 1.1e-19 70.7 0.8 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ60590.1 - 1.2e-19 70.3 1.9 1.1e-18 67.2 0.1 3.3 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CDJ60590.1 - 4.1e-07 30.5 1.9 0.71 10.3 0.0 5.4 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDJ60590.1 - 7.1e-06 26.5 8.1 2.4 8.5 0.0 6.9 6 1 1 7 7 7 1 AAA ATPase domain AAA_22 PF13401.6 CDJ60590.1 - 0.00012 22.4 7.0 1.3 9.3 0.0 6.1 7 0 0 7 7 4 1 AAA domain AAA_18 PF13238.6 CDJ60590.1 - 0.0076 16.8 1.4 6.4 7.3 0.0 4.4 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 CDJ60590.1 - 0.015 14.3 0.0 0.12 11.4 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_29 PF13555.6 CDJ60590.1 - 0.032 14.0 0.5 0.6 9.9 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CDJ60590.1 - 0.034 14.3 1.1 2.9 8.0 0.0 3.5 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 CDJ60590.1 - 0.041 14.0 0.1 0.33 11.1 0.0 2.7 3 0 0 3 3 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CDJ60590.1 - 0.045 14.0 0.2 14 5.9 0.0 4.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CDJ60590.1 - 0.067 12.6 0.3 0.62 9.4 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDJ60590.1 - 0.074 12.8 0.0 23 4.7 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Nab2 PF11517.8 CDJ60590.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.2 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RNA_helicase PF00910.22 CDJ60590.1 - 0.12 12.8 0.2 13 6.3 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 CDJ60590.1 - 0.76 10.1 9.3 12 6.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 CDJ60590.1 - 4.5 7.0 8.9 6.8 6.4 0.1 3.9 4 0 0 4 4 4 0 AAA domain Chorein_N PF12624.7 CDJ60591.1 - 6.3e-21 74.7 0.1 1.5e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ60591.1 - 3.4e-07 30.3 0.0 5.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal zf-ZPR1 PF03367.13 CDJ60591.1 - 0.12 12.2 0.6 1 9.2 0.0 2.6 3 0 0 3 3 3 0 ZPR1 zinc-finger domain VPS13_C PF16909.5 CDJ60592.1 - 4.6e-16 59.1 0.0 9.2e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CDJ60592.1 - 1.5e-12 47.5 0.0 4.7e-09 36.0 0.0 3.3 3 1 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 IF4E PF01652.18 CDJ60593.1 - 1.6e-08 34.5 0.0 5.6e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E PS_Dcarbxylase PF02666.15 CDJ60594.1 - 3.6e-31 108.3 0.0 6.3e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AP2 PF00847.20 CDJ60596.1 - 5.7e-11 42.5 0.4 5.7e-11 42.5 0.4 2.7 4 0 0 4 4 4 1 AP2 domain RskA PF10099.9 CDJ60596.1 - 0.033 14.5 0.0 0.033 14.5 0.0 3.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ60596.1 - 0.66 10.1 7.8 1.1 9.3 7.8 1.3 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 CDJ60596.1 - 1.3 8.7 8.4 2 8.2 8.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FemAB PF02388.16 CDJ60596.1 - 2.2 7.1 12.5 3.1 6.6 12.5 1.1 1 0 0 1 1 1 0 FemAB family RRS1 PF04939.12 CDJ60596.1 - 2.6 7.9 17.3 4.3 7.2 17.3 1.2 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Neur_chan_memb PF02932.16 CDJ60596.1 - 2.7 8.0 5.6 4.7 7.2 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Slu7 PF11708.8 CDJ60596.1 - 4 7.1 17.9 6 6.5 17.9 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor PIEZO PF15917.5 CDJ60596.1 - 4.8 6.6 17.9 7.6 5.9 17.9 1.2 1 0 0 1 1 1 0 Piezo DUF2722 PF10846.8 CDJ60597.1 - 0.048 12.6 3.2 0.097 11.6 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SR-25 PF10500.9 CDJ60598.1 - 0.011 15.4 29.8 0.017 14.7 29.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 CDJ60598.1 - 0.2 11.4 15.5 0.25 11.2 15.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CDJ60598.1 - 0.28 9.4 19.2 0.32 9.2 19.2 1.0 1 0 0 1 1 1 0 CDC45-like protein MID_MedPIWI PF18296.1 CDJ60598.1 - 0.54 10.0 9.0 0.67 9.7 9.0 1.1 1 0 0 1 1 1 0 MID domain of medPIWI GAGA_bind PF06217.12 CDJ60598.1 - 0.55 10.5 14.0 0.69 10.2 14.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family EOS1 PF12326.8 CDJ60598.1 - 0.76 9.7 6.8 1 9.2 6.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Med19 PF10278.9 CDJ60598.1 - 1.2 9.0 31.4 0.34 10.8 28.2 1.6 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF913 PF06025.12 CDJ60598.1 - 1.8 7.5 7.9 1.9 7.4 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nucleo_P87 PF07267.11 CDJ60598.1 - 2.1 7.1 14.9 2.5 6.8 14.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA_11 PF13086.6 CDJ60598.1 - 2.7 7.7 13.7 3.4 7.4 13.7 1.2 1 0 0 1 1 1 0 AAA domain DUF1168 PF06658.12 CDJ60598.1 - 2.8 7.7 37.1 0.26 11.1 31.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Vfa1 PF08432.10 CDJ60598.1 - 3.4 8.0 26.5 1 9.7 23.4 1.5 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rubella_Capsid PF05750.11 CDJ60598.1 - 6.4 6.3 7.0 8.4 5.9 7.0 1.2 1 0 0 1 1 1 0 Rubella capsid protein FGF-BP1 PF06473.12 CDJ60598.1 - 7 6.4 22.2 15 5.3 22.2 1.4 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SprA-related PF12118.8 CDJ60598.1 - 8.2 5.5 17.2 9.8 5.2 17.2 1.1 1 0 0 1 1 1 0 SprA-related family NPR3 PF03666.13 CDJ60598.1 - 8.9 5.0 17.5 11 4.7 17.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CDJ60598.1 - 10 6.1 10.3 12 5.9 10.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region N_NLPC_P60 PF12912.7 CDJ60599.1 - 6.2 7.2 6.7 9.1 6.7 1.1 2.7 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term Lipase_3 PF01764.25 CDJ60601.1 - 4.3e-13 49.3 0.0 8.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ist1 PF03398.14 CDJ60602.1 - 7.8e-21 74.7 0.7 5.9e-09 36.1 1.1 2.5 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway V_ATPase_I PF01496.19 CDJ60602.1 - 0.4 8.6 0.9 0.53 8.1 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CDJ60602.1 - 0.66 9.5 9.2 1 8.9 9.2 1.2 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ60602.1 - 0.9 9.5 3.3 1.6 8.7 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDJ60602.1 - 1.7 7.3 4.1 2.5 6.8 4.1 1.1 1 0 0 1 1 1 0 Presenilin Chorein_N PF12624.7 CDJ60603.1 - 5.6e-30 103.8 0.0 5.6e-30 103.8 0.0 2.9 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CDJ60603.1 - 2.8e-14 53.5 7.2 8.7e-13 48.6 0.0 3.7 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CDJ60603.1 - 1.3e-05 24.8 0.0 7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDJ60603.1 - 2.9e-05 24.3 0.0 0.00019 21.7 0.0 2.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CDJ60603.1 - 0.13 12.0 3.4 21 4.9 0.1 3.6 2 1 1 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal 2-Hacid_dh_C PF02826.19 CDJ60604.1 - 3.5e-33 114.5 0.0 5.4e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tn7_Tnp_TnsA_C PF08721.11 CDJ60604.1 - 0.13 12.9 0.0 0.58 10.8 0.0 2.0 2 0 0 2 2 2 0 TnsA endonuclease C terminal Amino_oxidase PF01593.24 CDJ60605.1 - 1.3e-20 74.1 0.0 1.9e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ60605.1 - 2.6e-09 37.2 0.4 8.3e-09 35.6 0.4 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDJ60605.1 - 2.9e-05 23.8 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDJ60605.1 - 0.001 18.3 0.0 0.0068 15.5 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 CDJ60605.1 - 0.0081 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDJ60605.1 - 0.039 13.2 0.1 0.081 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ60605.1 - 0.04 13.2 0.6 0.13 11.5 0.0 2.0 3 0 0 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 CDJ60605.1 - 0.052 12.8 0.2 0.2 10.9 0.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CDJ60605.1 - 0.068 13.7 0.0 0.2 12.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 CDJ60606.1 - 9.2e-41 139.9 0.1 3e-38 131.6 0.1 2.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Alba PF01918.21 CDJ60609.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Alba DUF3396 PF11876.8 CDJ60609.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3396) DUF3948 PF13134.6 CDJ60609.1 - 7 6.4 6.4 27 4.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Lin-8 PF03353.15 CDJ60610.1 - 0.051 13.1 16.2 0.064 12.8 16.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist V_ATPase_I PF01496.19 CDJ60610.1 - 0.16 9.8 12.1 0.17 9.8 12.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 CDJ60610.1 - 0.18 11.8 19.1 0.24 11.4 19.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCSAP PF15748.5 CDJ60610.1 - 0.2 11.8 17.4 0.25 11.5 17.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FapA PF03961.13 CDJ60610.1 - 0.4 9.2 9.7 0.51 8.9 9.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM83 PF07894.12 CDJ60610.1 - 0.65 9.5 12.6 0.95 9.0 12.6 1.3 1 0 0 1 1 1 0 FAM83 A-H PAT1 PF09770.9 CDJ60610.1 - 0.92 7.7 35.2 1 7.5 35.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CDJ60610.1 - 1.5 8.6 15.2 2.2 8.0 15.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Draxin PF15550.6 CDJ60610.1 - 1.6 8.5 14.2 2.1 8.1 14.2 1.2 1 0 0 1 1 1 0 Draxin GREB1 PF15782.5 CDJ60610.1 - 3.1 4.8 18.3 3.3 4.7 18.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LCIB_C_CA PF18599.1 CDJ60610.1 - 3.6 6.8 17.4 0.24 10.7 12.3 1.5 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Pex14_N PF04695.13 CDJ60610.1 - 3.7 8.2 40.1 2.1e+02 2.5 40.1 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4045 PF13254.6 CDJ60610.1 - 7.8 6.0 17.9 10 5.7 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.16 CDJ60610.1 - 8.5 6.4 18.1 12 5.9 18.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 CDJ60610.1 - 9.2 5.2 11.5 11 5.0 11.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein SUIM_assoc PF16619.5 CDJ60611.1 - 0.014 15.4 25.6 0.16 12.1 8.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ60611.1 - 0.32 10.6 30.0 0.29 10.7 6.5 2.1 2 0 0 2 2 2 0 Spt20 family Pkinase PF00069.25 CDJ60612.1 - 2.3e-07 30.4 0.0 5.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDJ60612.1 - 0.0081 15.5 0.6 0.032 13.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Utp14 PF04615.13 CDJ60613.1 - 0.0001 21.1 14.4 0.0001 21.1 14.4 17.3 3 2 11 17 17 17 1 Utp14 protein RskA PF10099.9 CDJ60613.1 - 0.0036 17.6 3.9 0.0036 17.6 3.9 41.3 7 5 16 26 26 26 3 Anti-sigma-K factor rskA Pentapeptide_4 PF13599.6 CDJ60613.1 - 5.2 7.3 10.9 4.8 7.4 2.7 2.4 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) DUF3899 PF13038.6 CDJ60613.1 - 6.2 7.4 6.0 10 6.7 0.4 4.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MOLO1 PF17175.4 CDJ60614.1 - 1.2 9.3 6.0 3.1 8.0 6.0 1.7 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 CCDC106 PF15794.5 CDJ60616.1 - 0.01 15.6 18.9 0.013 15.3 18.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NICE-1 PF15845.5 CDJ60616.1 - 0.055 14.2 30.9 0.072 13.9 30.9 1.1 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Apt1 PF10351.9 CDJ60616.1 - 3 6.6 21.3 3.5 6.4 21.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ60616.1 - 3.6 5.8 12.1 4.3 5.5 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 CDJ60616.1 - 3.6 6.0 22.2 4.1 5.9 22.2 1.0 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CDJ60616.1 - 5 7.0 15.1 5.7 6.8 15.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDK2AP PF09806.9 CDJ60616.1 - 6.4 6.8 15.5 7.6 6.5 15.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4207 PF13904.6 CDJ60616.1 - 7.5 6.2 16.7 9 5.9 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Presenilin PF01080.17 CDJ60616.1 - 9.8 4.8 12.3 11 4.7 12.3 1.0 1 0 0 1 1 1 0 Presenilin Sec23_trunk PF04811.15 CDJ60618.1 - 5.1e-38 131.0 0.1 7.1e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDJ60618.1 - 1.2e-30 106.1 0.1 2e-29 102.2 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDJ60618.1 - 4e-24 84.4 0.5 8.2e-24 83.4 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDJ60618.1 - 1.2e-13 50.9 3.2 3.3e-13 49.4 3.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDJ60618.1 - 1.5e-11 44.0 0.0 4.3e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Gelsolin repeat Rad51 PF08423.11 CDJ60619.1 - 1.2e-118 395.0 0.0 2.1e-118 394.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CDJ60619.1 - 6.5e-09 35.6 0.0 9.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CDJ60619.1 - 1.9e-06 27.6 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDJ60619.1 - 0.00036 20.0 0.0 0.0007 19.0 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CDJ60619.1 - 0.00056 20.5 0.3 0.0016 19.0 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 CDJ60619.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NMT_C PF02799.15 CDJ60620.1 - 5.8e-56 189.3 0.0 8.5e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CDJ60620.1 - 1.1e-24 87.1 0.1 9.9e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain TPR_MLP1_2 PF07926.12 CDJ60621.1 - 0.0039 17.3 23.8 0.0039 17.3 23.8 10.6 3 3 5 10 10 10 2 TPR/MLP1/MLP2-like protein zf-CCCH PF00642.24 CDJ60622.1 - 2.9e-07 30.2 18.5 0.00015 21.6 0.8 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDJ60622.1 - 1.2e-05 25.5 10.0 0.0072 16.5 3.1 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 CDJ60622.1 - 0.0051 16.5 2.8 0.16 11.7 1.7 2.6 2 0 0 2 2 2 1 Putative zinc-finger domain Torus PF16131.5 CDJ60622.1 - 0.0087 16.7 23.5 0.08 13.7 0.0 4.4 2 1 2 4 4 4 2 Torus domain zf-CCCH_2 PF14608.6 CDJ60622.1 - 0.03 14.8 0.9 0.03 14.8 0.9 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDJ60622.1 - 0.067 13.0 23.5 0.062 13.1 5.7 3.8 3 1 0 3 3 3 0 CCCH-type zinc finger GET2 PF08690.10 CDJ60622.1 - 0.15 11.8 1.2 0.29 10.8 1.2 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 CDJ60622.1 - 0.41 10.6 22.6 0.047 13.7 16.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf_CCCH_4 PF18345.1 CDJ60622.1 - 2.6 8.2 28.8 0.72 10.0 3.4 4.5 4 1 0 4 4 4 0 Zinc finger domain GETHR PF05671.11 CDJ60624.1 - 0.003 16.9 10.5 0.0042 16.4 0.6 3.5 1 1 3 5 5 5 3 GETHR pentapeptide repeat (5 copies) MAP7 PF05672.11 CDJ60624.1 - 3.1 7.5 48.7 0.17 11.6 28.9 3.3 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family SpoIIP PF07454.11 CDJ60624.1 - 3.9 6.9 19.4 2.4 7.6 9.2 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Mito_carr PF00153.27 CDJ60625.1 - 6.1e-33 112.6 3.1 3.9e-15 55.5 0.4 3.6 2 2 0 2 2 2 2 Mitochondrial carrier protein Rpr2 PF04032.16 CDJ60626.1 - 0.01 16.1 0.3 0.01 16.1 0.3 4.6 3 1 2 5 5 5 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_1 PF00515.28 CDJ60627.1 - 8.7e-08 31.7 0.8 0.0065 16.2 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60627.1 - 1.3e-05 24.9 2.6 0.016 15.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ60627.1 - 0.00027 21.4 0.5 0.00087 19.7 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ60627.1 - 0.0018 18.9 2.8 0.011 16.4 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60627.1 - 0.0043 17.2 0.6 3.3 8.2 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ60627.1 - 0.032 13.9 0.5 0.093 12.4 0.5 1.9 1 1 0 1 1 1 0 TPR repeat ANAPC3 PF12895.7 CDJ60627.1 - 0.034 14.3 1.0 0.2 11.9 1.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDJ60627.1 - 0.041 14.2 1.4 0.17 12.2 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CDJ60627.1 - 0.086 12.9 1.3 33 4.7 0.0 3.7 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CDJ60627.1 - 0.73 10.6 5.7 11 6.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CsiV PF10972.8 CDJ60627.1 - 3 7.5 7.5 7 6.3 3.5 2.8 1 1 1 2 2 2 0 Peptidoglycan-binding protein, CsiV TPR_14 PF13428.6 CDJ60627.1 - 6.2 7.9 6.7 2 9.4 0.5 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CDJ60628.1 - 0.00018 20.4 0.2 0.25 10.1 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like TMEM232 PF15877.5 CDJ60628.1 - 0.18 10.7 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 232 TFIIA PF03153.13 CDJ60628.1 - 2.5 8.0 37.4 0.84 9.6 19.7 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DNA_pol3_delta2 PF13177.6 CDJ60629.1 - 2.1e-09 37.3 0.0 1e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CDJ60629.1 - 8e-09 36.0 0.0 3.8e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ60629.1 - 3.4e-05 24.1 0.0 0.00014 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CDJ60629.1 - 0.00012 22.4 0.6 0.00036 20.8 0.3 2.0 2 0 0 2 2 2 1 AAA C-terminal domain Rep_fac_C PF08542.11 CDJ60629.1 - 0.00015 22.1 0.1 0.00033 21.0 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_30 PF13604.6 CDJ60629.1 - 0.00016 21.5 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDJ60629.1 - 0.00023 20.6 0.1 0.001 18.5 0.0 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ60629.1 - 0.00029 20.8 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CDJ60629.1 - 0.00038 20.9 0.1 0.0094 16.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDJ60629.1 - 0.00041 20.3 0.1 0.0052 16.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDJ60629.1 - 0.00045 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CDJ60629.1 - 0.00049 20.4 0.1 0.0034 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 CDJ60629.1 - 0.0021 17.9 0.0 0.84 9.4 0.0 2.6 3 0 0 3 3 2 1 DEAD/DEAH box helicase TIP49 PF06068.13 CDJ60629.1 - 0.0023 17.2 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MeaB PF03308.16 CDJ60629.1 - 0.0025 16.8 0.3 0.21 10.5 0.0 2.6 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDJ60629.1 - 0.0026 18.3 0.0 0.013 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDJ60629.1 - 0.0046 16.3 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDJ60629.1 - 0.013 15.3 0.1 0.037 13.8 0.0 1.8 3 0 0 3 3 1 0 AAA domain AAA_14 PF13173.6 CDJ60629.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CDJ60629.1 - 0.023 14.8 0.0 0.13 12.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDJ60629.1 - 0.024 14.8 0.3 0.076 13.2 0.1 2.0 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CDJ60629.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDJ60629.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 CDJ60629.1 - 0.05 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 CDJ60629.1 - 0.095 12.0 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family SNF2_N PF00176.23 CDJ60629.1 - 0.12 11.0 0.0 0.69 8.6 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.15 CDJ60629.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 CDJ60629.1 - 0.13 12.5 0.2 0.7 10.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain TIP49_C PF17856.1 CDJ60629.1 - 0.14 12.3 0.5 0.35 11.0 0.5 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_7 PF12775.7 CDJ60629.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SprA-related PF12118.8 CDJ60630.1 - 5.5e-05 22.5 34.5 7e-05 22.1 34.5 1.1 1 0 0 1 1 1 1 SprA-related family Androgen_recep PF02166.16 CDJ60630.1 - 0.0044 15.9 23.5 0.0044 15.9 23.5 2.2 2 0 0 2 2 2 1 Androgen receptor Presenilin PF01080.17 CDJ60630.1 - 0.033 13.0 16.3 0.044 12.6 16.3 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CDJ60630.1 - 0.034 14.1 0.4 0.034 14.1 0.4 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit RXLR PF16810.5 CDJ60630.1 - 0.059 13.8 24.4 0.035 14.5 7.9 2.1 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity eIF-3_zeta PF05091.12 CDJ60630.1 - 0.081 11.9 14.7 0.1 11.6 14.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ60630.1 - 0.13 12.8 17.7 0.2 12.2 17.7 1.2 1 0 0 1 1 1 0 TCP family transcription factor Hamartin PF04388.12 CDJ60630.1 - 0.48 9.0 12.5 0.58 8.8 12.5 1.1 1 0 0 1 1 1 0 Hamartin protein Nop14 PF04147.12 CDJ60630.1 - 0.51 8.5 18.2 0.63 8.2 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family SWI-SNF_Ssr4 PF08549.10 CDJ60630.1 - 0.61 8.7 25.2 0.86 8.2 25.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Cwf_Cwc_15 PF04889.12 CDJ60630.1 - 0.65 9.7 24.4 0.79 9.4 13.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 CDJ60630.1 - 0.72 9.2 25.9 0.94 8.8 25.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4551 PF15087.6 CDJ60630.1 - 1.5 7.5 14.9 1.9 7.2 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FSA_C PF10479.9 CDJ60630.1 - 1.6 6.8 8.3 2.7 6.0 8.3 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CEP19 PF14933.6 CDJ60630.1 - 2.1 8.7 16.3 8 6.7 10.8 2.1 2 0 0 2 2 2 0 CEP19-like protein NST1 PF13945.6 CDJ60630.1 - 2.8 8.0 19.0 0.38 10.8 10.2 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator RskA PF10099.9 CDJ60630.1 - 3.3 8.0 44.9 5.6e+02 0.7 44.8 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ60630.1 - 3.9 5.6 5.9 4.7 5.4 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) VIR_N PF15912.5 CDJ60630.1 - 6.9 6.2 13.9 8.4 5.9 13.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PepSY_2 PF13670.6 CDJ60630.1 - 7 6.7 24.4 0.36 10.9 6.0 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF4834 PF16118.5 CDJ60630.1 - 7.8 7.5 21.0 3.5 8.7 15.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Plasmodium_Vir PF05795.11 CDJ60630.1 - 8 5.8 17.5 45 3.3 17.5 1.9 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF5327 PF17261.2 CDJ60630.1 - 8.3 7.2 26.6 5.6 7.8 17.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF702 PF05142.12 CDJ60630.1 - 9.3 6.7 15.1 0.39 11.2 6.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) RRM_1 PF00076.22 CDJ60631.1 - 9e-13 47.8 0.0 2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 CDJ60632.1 - 8.9e-06 25.5 6.9 8.9e-06 25.5 6.9 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 CDJ60635.1 - 1.3 9.3 50.2 0.2 12.0 18.6 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 SMC_N PF02463.19 CDJ60637.1 - 6e-27 94.5 63.5 1.3e-25 90.1 0.1 6.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDJ60637.1 - 7.9e-16 58.4 0.0 7.9e-16 58.4 0.0 3.6 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CDJ60637.1 - 1e-08 35.3 10.5 1e-08 35.3 10.5 5.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CDJ60637.1 - 6.8e-07 29.4 0.0 2.7e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDJ60637.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2722 PF10846.8 CDJ60638.1 - 1.3 7.9 11.8 0.019 13.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ60638.1 - 8.5 6.2 22.1 12 5.7 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GrpE PF01025.19 CDJ60639.1 - 9.5e-36 123.0 6.0 1.5e-35 122.3 6.0 1.4 1 0 0 1 1 1 1 GrpE Activator_LAG-3 PF11498.8 CDJ60639.1 - 0.00069 18.7 7.3 0.00091 18.3 7.3 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 MRP-S31 PF15433.6 CDJ60639.1 - 0.032 13.9 6.3 0.045 13.4 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Spt20 PF12090.8 CDJ60639.1 - 0.084 12.5 8.7 0.15 11.6 8.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ60639.1 - 0.2 10.6 12.5 0.033 13.2 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1664 PF07889.12 CDJ60639.1 - 0.29 11.2 4.2 0.16 12.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CDJ60639.1 - 0.79 10.5 4.3 1.5 9.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cluap1 PF10234.9 CDJ60639.1 - 0.84 9.0 10.4 1.2 8.5 10.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 GET2 PF08690.10 CDJ60639.1 - 0.93 9.1 10.7 1.4 8.5 10.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 STAG PF08514.11 CDJ60639.1 - 1.6 8.7 4.8 2.5 8.0 4.4 1.5 1 1 0 1 1 1 0 STAG domain CREPT PF16566.5 CDJ60639.1 - 1.8 8.7 11.0 6.9 6.8 1.0 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TPPII_N PF12583.8 CDJ60639.1 - 2.3 8.8 7.9 4.9 7.7 7.9 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF4559 PF15112.6 CDJ60639.1 - 3.8 7.1 8.7 4.8 6.8 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ARL2_Bind_BART PF11527.8 CDJ60642.1 - 0.00047 20.2 1.3 0.45 10.6 0.1 3.5 3 1 1 4 4 4 3 The ARF-like 2 binding protein BART TRAUB PF08164.12 CDJ60643.1 - 2.1e-11 44.2 0.0 2.1e-11 44.2 0.0 3.5 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CDJ60643.1 - 0.0011 19.6 9.5 0.0011 19.6 9.5 2.4 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor MAM33 PF02330.16 CDJ60646.1 - 0.055 13.4 0.2 0.08 12.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein SR-25 PF10500.9 CDJ60646.1 - 0.14 11.8 24.7 0.03 13.9 10.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ABC1 PF03109.16 CDJ60647.1 - 1.2e-24 86.8 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDJ60647.1 - 0.11 12.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family RabGAP-TBC PF00566.18 CDJ60648.1 - 4.9e-29 101.5 2.9 8.8e-28 97.4 0.1 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Macoilin PF09726.9 CDJ60648.1 - 0.3 9.6 15.3 0.013 14.1 3.0 2.2 2 0 0 2 2 2 0 Macoilin family Kinase-like PF14531.6 CDJ60649.1 - 3.3e-16 59.4 0.0 5.9e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 CDJ60649.1 - 0.00018 21.0 0.0 0.00072 19.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60649.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Mito_carr PF00153.27 CDJ60650.1 - 2.9e-40 136.1 7.6 4.9e-21 74.5 0.8 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Adap_comp_sub PF00928.21 CDJ60651.1 - 8.8e-87 290.8 0.0 1.1e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDJ60651.1 - 1.5e-05 25.0 0.2 2.8e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Presenilin PF01080.17 CDJ60652.1 - 0.0037 16.1 17.9 0.0037 16.1 17.9 6.2 3 2 1 4 4 4 1 Presenilin RskA PF10099.9 CDJ60652.1 - 0.0097 16.2 89.9 0.011 16.1 16.3 8.0 4 2 2 6 6 6 3 Anti-sigma-K factor rskA Nucleoporin_FG PF13634.6 CDJ60653.1 - 1.5e-23 83.5 362.9 1.4e-07 32.3 31.6 14.5 7 4 6 14 14 14 10 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CDJ60653.1 - 1.8e-06 28.2 0.7 1.8e-06 28.2 0.7 3.6 4 0 0 4 4 4 1 Nucleoporin autopeptidase AAA_23 PF13476.6 CDJ60653.1 - 0.0012 19.4 0.1 0.0012 19.4 0.1 7.0 6 2 0 6 6 6 1 AAA domain DUF737 PF05300.11 CDJ60655.1 - 2.1 8.6 13.9 0.29 11.5 8.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF737) GMC_oxred_C PF05199.13 CDJ60656.1 - 3.5e-19 69.8 0.1 1.6e-14 54.6 0.1 2.6 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 CDJ60656.1 - 2.2e-16 60.1 0.1 2.9e-07 30.2 0.0 2.8 3 0 0 3 3 3 2 GMC oxidoreductase NAD_binding_8 PF13450.6 CDJ60656.1 - 9.4e-05 22.6 0.4 0.0003 20.9 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CDJ60656.1 - 0.00078 18.8 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 CDJ60656.1 - 0.0011 18.1 1.3 0.0046 16.1 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDJ60656.1 - 0.0016 18.1 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDJ60656.1 - 0.0028 16.9 0.7 0.0061 15.8 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDJ60656.1 - 0.003 16.9 0.1 0.065 12.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ60656.1 - 0.0036 16.1 0.1 0.0053 15.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 CDJ60656.1 - 0.0039 16.3 0.2 0.0066 15.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 CDJ60656.1 - 0.0051 17.3 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 CDJ60656.1 - 0.0063 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.22 CDJ60656.1 - 0.018 14.1 0.6 0.032 13.3 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDJ60656.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sin3_corepress PF08295.12 CDJ60657.1 - 3.6e-23 81.5 0.2 9.1e-23 80.2 0.2 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Adaptin_binding PF10199.9 CDJ60657.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.3 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 FSA_C PF10479.9 CDJ60657.1 - 7.6 4.5 9.8 12 3.8 9.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Laminin_G_3 PF13385.6 CDJ60658.1 - 1.9e-15 57.3 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ60658.1 - 3.9e-05 24.2 0.0 0.00015 22.4 0.0 2.0 2 1 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CDJ60658.1 - 7.9e-05 22.9 0.0 0.00016 21.9 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain DUF3774 PF12609.8 CDJ60659.1 - 1 10.4 0.0 1 10.4 0.0 5.2 3 1 0 3 3 3 0 Wound-induced protein DNA_pol_A PF00476.20 CDJ60660.1 - 1.1e-50 172.8 0.1 3.1e-36 125.2 1.2 2.2 2 0 0 2 2 2 2 DNA polymerase family A TFIIA PF03153.13 CDJ60660.1 - 6 6.7 36.4 0.2 11.6 3.0 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit V-SNARE_C PF12352.8 CDJ60661.1 - 0.00011 22.5 1.5 0.00011 22.5 1.5 3.9 4 0 0 4 4 4 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDJ60661.1 - 0.0011 18.9 0.9 0.0011 18.9 0.9 3.2 3 1 1 4 4 4 1 Sec20 DUF948 PF06103.11 CDJ60661.1 - 0.2 12.0 6.8 5.2 7.4 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 CDJ60661.1 - 0.77 10.3 4.2 0.21 12.1 0.4 1.9 2 0 0 2 2 2 0 PhoU domain CCDC53 PF10152.9 CDJ60663.1 - 0.093 13.1 8.6 0.066 13.6 1.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2229 PF09989.9 CDJ60663.1 - 1 9.0 6.2 0.11 12.1 1.2 1.8 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Pex14_N PF04695.13 CDJ60663.1 - 2.3 8.9 15.2 4 8.1 8.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CDJ60663.1 - 8 6.0 34.7 7.8 6.0 4.2 2.2 2 0 0 2 2 2 0 Spt20 family PHD PF00628.29 CDJ60664.1 - 4.8e-06 26.4 6.0 4.8e-06 26.4 6.0 3.8 4 0 0 4 4 4 2 PHD-finger PH PF00169.29 CDJ60665.1 - 1.1e-05 25.9 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 CDJ60665.1 - 0.003 17.8 0.1 0.0046 17.2 0.1 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PBP1_TM PF14812.6 CDJ60665.1 - 0.018 15.4 0.3 0.038 14.4 0.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PH_TFIIH PF08567.11 CDJ60665.1 - 0.023 15.0 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain PH_16 PF17838.1 CDJ60665.1 - 0.026 14.4 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 PH domain MSP1_C PF07462.11 CDJ60665.1 - 0.06 12.0 3.8 0.082 11.6 3.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1373 PF07117.11 CDJ60665.1 - 0.54 10.2 5.3 1.3 9.0 3.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1373) LRR_9 PF14580.6 CDJ60666.1 - 2.5e-06 27.1 1.4 2.5e-06 27.1 1.4 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CDJ60666.1 - 0.0014 18.9 9.2 0.01 16.3 0.2 3.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Coilin_N PF15862.5 CDJ60666.1 - 0.0021 17.9 3.3 0.0021 17.9 3.3 1.7 2 0 0 2 2 2 1 Coilin N-terminus LRR_8 PF13855.6 CDJ60666.1 - 0.018 14.8 1.4 0.018 14.8 1.4 2.0 2 0 0 2 2 2 0 Leucine rich repeat DUF775 PF05603.12 CDJ60666.1 - 0.06 12.9 6.3 0.099 12.2 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2992 PF11208.8 CDJ60666.1 - 0.23 11.7 19.0 0.36 11.1 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) CLN3 PF02487.17 CDJ60666.1 - 0.82 8.6 5.5 1.2 8.1 5.5 1.2 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 CDJ60666.1 - 0.82 9.7 8.2 0.89 9.6 7.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 CDJ60666.1 - 0.97 8.2 12.6 1.6 7.5 12.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter YABBY PF04690.13 CDJ60666.1 - 9.7 6.7 10.8 20 5.7 10.8 1.5 1 0 0 1 1 1 0 YABBY protein Apolipoprotein PF01442.18 CDJ60668.1 - 0.0065 16.4 0.1 0.031 14.2 0.1 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 CDJ60668.1 - 0.0075 14.3 0.4 0.0096 13.9 0.4 1.2 1 0 0 1 1 1 1 Prominin Desmo_N PF06771.11 CDJ60668.1 - 0.026 14.9 0.4 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus N2227 PF07942.12 CDJ60668.1 - 0.077 12.2 0.1 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 N2227-like protein HalX PF08663.10 CDJ60668.1 - 0.078 13.3 0.7 21 5.6 0.0 3.2 2 1 1 3 3 3 0 HalX domain zf-LITAF-like PF10601.9 CDJ60671.1 - 1.8e-11 44.2 2.4 3.1e-11 43.4 2.4 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain RCC1 PF00415.18 CDJ60672.1 - 2.5e-25 88.8 22.0 1.2e-08 35.4 1.5 8.3 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ60672.1 - 5.1e-12 45.3 37.9 6.6e-06 25.8 3.6 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 CDJ60673.1 - 4e-38 128.8 52.9 1.8e-09 37.7 3.3 7.1 3 2 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ60673.1 - 1.3e-32 111.3 57.6 9.1e-09 35.0 1.2 5.7 1 1 6 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 CDJ60673.1 - 2.2e-23 82.7 11.2 7.2e-07 28.9 0.0 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CDJ60673.1 - 0.091 13.4 32.8 3.5 8.5 0.5 9.2 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 CDJ60673.1 - 0.44 10.7 27.3 0.17 12.0 0.8 7.1 8 0 0 8 8 8 0 Leucine Rich repeat RT_RNaseH_2 PF17919.1 CDJ60674.1 - 2.1e-22 79.0 0.0 2.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDJ60674.1 - 7.1e-13 48.7 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDJ60674.1 - 0.00031 20.4 0.0 0.00057 19.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Utp14 PF04615.13 CDJ60675.1 - 0.0018 17.0 34.8 0.0018 17.0 34.8 8.5 3 1 3 6 6 6 2 Utp14 protein DUF1676 PF07898.13 CDJ60675.1 - 3 7.9 0.0 3 7.9 0.0 11.6 7 5 5 13 13 13 0 Protein of unknown function (DUF1676) KBP_C PF12309.8 CDJ60676.1 - 5.8e-10 39.2 0.2 5.8e-10 39.2 0.2 5.9 5 2 0 5 5 5 2 KIF-1 binding protein C terminal RskA PF10099.9 CDJ60676.1 - 0.00093 19.5 0.0 0.00093 19.5 0.0 14.7 2 1 5 8 8 8 2 Anti-sigma-K factor rskA FAM104 PF15434.6 CDJ60676.1 - 1.3 9.6 0.0 1.3 9.6 0.0 11.5 8 3 3 11 11 11 0 Family 104 TPR_10 PF13374.6 CDJ60677.1 - 0.0066 16.3 0.3 0.0066 16.3 0.3 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Adeno_terminal PF02459.15 CDJ60677.1 - 0.76 8.1 5.1 2.2 6.6 5.1 1.7 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CCDC106 PF15794.5 CDJ60678.1 - 0.00094 19.0 3.1 0.0013 18.5 3.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDJ60678.1 - 0.051 12.1 4.5 0.049 12.2 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CDJ60678.1 - 0.4 9.5 5.5 0.44 9.4 5.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 CDJ60678.1 - 0.67 8.2 8.9 0.78 7.9 8.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.18 CDJ60678.1 - 0.7 8.9 6.2 0.85 8.6 6.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-C3HC4_3 PF13920.6 CDJ60679.1 - 1.7e-12 47.0 12.8 3.5e-12 46.0 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ60679.1 - 1e-07 31.7 12.1 1.8e-07 30.9 12.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CDJ60679.1 - 0.00018 21.8 13.5 0.00036 20.8 13.5 1.5 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 CDJ60679.1 - 0.15 12.0 19.0 0.12 12.3 11.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_14 PF17978.1 CDJ60679.1 - 0.86 10.1 5.8 1.9 9.0 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1180 PF06679.12 CDJ60679.1 - 3.2 8.1 26.8 0.83 10.0 2.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) zf-RING_4 PF14570.6 CDJ60679.1 - 3.6 7.4 10.4 6.6 6.6 10.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SUIM_assoc PF16619.5 CDJ60679.1 - 4.6 7.4 13.4 4.1 7.5 5.5 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CDJ60680.1 - 2e-53 181.4 0.0 4.6e-53 180.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60680.1 - 1e-20 74.2 0.0 2.1e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2268 PF10026.9 CDJ60680.1 - 0.004 16.7 0.8 0.0088 15.6 0.8 1.5 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) ABC1 PF03109.16 CDJ60680.1 - 0.007 16.5 0.0 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 CDJ60680.1 - 0.016 15.1 0.0 0.016 15.1 0.0 5.9 3 3 2 5 5 5 0 Phosphotransferase enzyme family Ribosomal_S9 PF00380.19 CDJ60683.1 - 7.9e-17 61.9 0.4 1.2e-16 61.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SRPRB PF09439.10 CDJ60684.1 - 1.1e-20 73.8 0.1 3.5e-15 55.9 0.0 2.1 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 CDJ60684.1 - 4.7e-08 32.7 0.0 4.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ60684.1 - 3.4e-05 23.5 0.0 5.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ60684.1 - 0.00016 21.7 0.0 0.0018 18.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDJ60684.1 - 0.0033 17.6 0.0 0.54 10.5 0.0 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ60684.1 - 0.0078 15.8 0.0 0.093 12.3 0.0 2.2 1 1 0 2 2 2 1 Ras family AAA_28 PF13521.6 CDJ60684.1 - 0.012 15.9 0.1 0.02 15.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDJ60684.1 - 0.018 15.4 0.9 0.03 14.7 0.6 1.5 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 CDJ60684.1 - 0.051 12.9 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDJ60684.1 - 0.062 12.8 0.1 1.5 8.3 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B ResIII PF04851.15 CDJ60684.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 CDJ60684.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase RCC1 PF00415.18 CDJ60685.1 - 1.9e-67 223.7 28.8 4.9e-09 36.7 0.1 13.6 13 0 0 13 13 13 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ60685.1 - 1.2e-26 91.9 55.0 4.3e-09 35.9 0.4 10.2 13 0 0 13 13 13 7 Regulator of chromosome condensation (RCC1) repeat K_channel_TID PF07941.11 CDJ60685.1 - 0.0072 16.8 19.1 0.0072 16.8 19.1 8.6 8 1 1 9 9 9 1 Potassium channel Kv1.4 tandem inactivation domain DUF2052 PF09747.9 CDJ60685.1 - 0.049 13.8 6.1 1.8 8.7 2.0 2.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) SUIM_assoc PF16619.5 CDJ60685.1 - 0.09 12.9 14.3 0.54 10.4 0.3 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Myc_N PF01056.18 CDJ60685.1 - 1.8 8.4 11.6 0.79 9.6 1.2 2.7 3 0 0 3 3 3 0 Myc amino-terminal region NOA36 PF06524.12 CDJ60685.1 - 2.7 7.2 7.0 5.5 6.2 2.0 2.2 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 CDJ60685.1 - 4.9 6.8 9.8 1.9 8.2 1.5 2.5 2 0 0 2 2 2 0 FAM176 family BSP_II PF05432.11 CDJ60685.1 - 7.9 6.1 19.1 4 7.0 4.2 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.9 CDJ60686.1 - 2.9e-05 22.9 11.2 5.2e-05 22.0 11.2 1.4 1 1 0 1 1 1 1 Macoilin family ELO PF01151.18 CDJ60686.1 - 0.0084 15.7 0.3 0.013 15.0 0.3 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family RskA PF10099.9 CDJ60686.1 - 0.0088 16.4 0.2 0.03 14.6 0.1 1.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA DDHD PF02862.17 CDJ60686.1 - 0.028 14.6 2.4 4.8 7.3 3.4 2.3 2 0 0 2 2 2 0 DDHD domain SID-1_RNA_chan PF13965.6 CDJ60686.1 - 0.051 12.0 0.1 0.06 11.8 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ60686.1 - 0.092 12.3 9.6 0.11 12.0 9.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.16 CDJ60686.1 - 0.83 9.7 3.7 3 7.8 3.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CK_II_beta PF01214.18 CDJ60686.1 - 4.7 7.0 6.4 3 7.6 4.3 1.6 1 1 0 1 1 1 0 Casein kinase II regulatory subunit Asp-B-Hydro_N PF05279.11 CDJ60686.1 - 8.3 6.4 14.2 11 6.0 14.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMPIT PF07851.13 CDJ60686.1 - 9.3 5.4 15.8 14 4.8 15.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-C2HC_2 PF13913.6 CDJ60687.1 - 4e-08 33.0 20.3 1.2e-06 28.2 4.3 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type Mito_carr PF00153.27 CDJ60688.1 - 4.7e-07 29.6 0.0 0.00053 19.9 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Hydin_ADK PF17213.3 CDJ60688.1 - 0.093 13.0 2.5 0.13 12.5 2.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4637 PF15470.6 CDJ60688.1 - 2.7 7.7 5.5 0.55 10.0 1.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4637) Kinesin PF00225.23 CDJ60689.1 - 0.00022 20.3 0.0 0.00022 20.3 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 CDJ60689.1 - 0.0012 19.0 0.7 0.0012 19.0 0.7 4.8 3 3 2 5 5 5 2 Kinesin-associated KIF1B PF12423.8 CDJ60689.1 - 0.0091 16.4 0.0 0.0091 16.4 0.0 2.8 3 0 0 3 3 3 1 Kinesin protein 1B FHA PF00498.26 CDJ60689.1 - 0.026 14.9 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 FHA domain UbiA PF01040.18 CDJ60690.1 - 3.9e-06 26.4 13.7 3.9e-06 26.4 13.7 3.0 1 1 1 3 3 3 1 UbiA prenyltransferase family DUF515 PF04415.12 CDJ60690.1 - 0.76 8.1 3.6 1.1 7.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Colicin_V PF02674.16 CDJ60690.1 - 9 6.3 17.3 0.12 12.4 8.6 2.3 2 2 0 2 2 2 0 Colicin V production protein DEAD PF00270.29 CDJ60692.1 - 5.7e-15 55.5 4.7 5.7e-15 55.5 4.7 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ60692.1 - 6.9e-10 39.3 16.2 8.2e-10 39.0 5.9 4.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Oxidored_q6 PF01058.22 CDJ60692.1 - 0.19 11.5 4.5 1.1 9.1 2.1 3.0 2 1 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit TT_ORF1 PF02956.14 CDJ60693.1 - 1.6 7.3 10.4 0.11 11.1 0.3 3.0 3 0 0 3 3 3 0 TT viral orf 1 PPP4R2 PF09184.11 CDJ60694.1 - 0.047 13.3 23.6 0.062 12.9 23.6 1.1 1 0 0 1 1 1 0 PPP4R2 DUF1840 PF08895.11 CDJ60694.1 - 0.79 10.1 12.9 1.1 9.7 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) MscS_TM PF12794.7 CDJ60694.1 - 1.1 8.1 6.9 1.4 7.7 6.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TFIIA PF03153.13 CDJ60694.1 - 1.1 9.2 35.3 1.6 8.6 35.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Synuclein PF01387.17 CDJ60694.1 - 5.3 7.2 8.3 11 6.3 8.3 1.5 1 0 0 1 1 1 0 Synuclein PNISR PF15996.5 CDJ60694.1 - 5.9 7.1 26.0 8.1 6.7 15.3 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR EF-hand_1 PF00036.32 CDJ60695.1 - 1.6e-40 133.6 10.2 1.2e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ60695.1 - 7.6e-35 119.2 1.9 5.3e-17 62.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDJ60695.1 - 1e-32 111.8 10.5 8.2e-16 57.6 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60695.1 - 7.1e-29 97.2 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ60695.1 - 4.9e-26 89.0 8.6 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDJ60695.1 - 4.3e-15 55.8 0.1 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDJ60695.1 - 2.3e-09 37.1 0.3 0.00039 20.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDJ60695.1 - 1.5e-07 31.7 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDJ60695.1 - 3.3e-06 27.9 0.0 0.0009 20.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CDJ60695.1 - 2.8e-05 24.0 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CDJ60695.1 - 0.00082 19.5 4.3 0.16 12.2 0.5 2.8 2 2 1 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 CDJ60695.1 - 0.0017 18.3 0.2 0.52 10.2 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.8 CDJ60695.1 - 0.0018 19.0 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 CDJ60695.1 - 0.0033 17.7 0.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.11 CDJ60695.1 - 0.0056 16.3 1.2 0.0067 16.1 1.2 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.10 CDJ60695.1 - 0.0068 16.5 0.4 0.042 13.9 0.0 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand YqeY PF09424.10 CDJ60695.1 - 0.012 15.6 0.2 0.15 12.1 0.1 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 CDJ60695.1 - 0.015 15.1 0.4 0.85 9.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CDJ60695.1 - 0.026 13.2 0.2 0.7 8.4 0.1 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 CDJ60695.1 - 0.035 14.4 0.1 9.2 6.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 CDJ60695.1 - 0.047 13.9 0.1 9.3 6.6 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 CDJ60695.1 - 0.071 11.6 0.0 0.071 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Fe_hyd_lg_C PF02906.14 CDJ60695.1 - 0.072 12.7 0.6 0.23 11.1 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 CDJ60695.1 - 0.095 12.7 0.0 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain SurA_N_3 PF13624.6 CDJ60695.1 - 0.1 12.4 0.2 0.44 10.3 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 CDJ60695.1 - 0.1 11.7 0.0 7.7 5.6 0.0 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 CDJ60695.1 - 0.12 12.6 0.4 2 8.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain CwfJ_C_1 PF04677.15 CDJ60696.1 - 5e-27 94.2 0.1 1.1e-26 93.1 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 CDJ60696.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 CDJ60696.1 - 2.1e-06 28.5 0.0 5.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Ank_4 PF13637.6 CDJ60698.1 - 2.8e-28 97.9 2.1 2.6e-08 34.3 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ60698.1 - 2.1e-26 92.3 0.0 5.5e-12 46.1 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ60698.1 - 2.7e-20 71.8 6.1 0.0082 16.5 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 CDJ60698.1 - 3.6e-18 63.8 0.6 0.025 15.1 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat RNA_GG_bind PF10258.9 CDJ60698.1 - 8.4e-17 61.0 0.0 8.4e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 PHAX RNA-binding domain Ank_5 PF13857.6 CDJ60698.1 - 4.4e-15 55.6 1.1 0.00095 19.4 0.0 5.4 2 2 2 5 5 5 5 Ankyrin repeats (many copies) DUF4464 PF14713.6 CDJ60699.1 - 2.4e-06 27.3 2.0 2.6e-06 27.2 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) SR-25 PF10500.9 CDJ60699.1 - 0.0029 17.2 5.0 0.0029 17.2 5.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ60699.1 - 0.009 16.1 4.0 0.009 16.1 4.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.8 CDJ60699.1 - 0.023 14.3 6.9 0.026 14.2 6.9 1.1 1 0 0 1 1 1 0 Spt20 family Corona_nucleoca PF00937.18 CDJ60699.1 - 0.87 8.6 8.5 0.92 8.5 8.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RskA PF10099.9 CDJ60700.1 - 2.2e-07 31.3 6.2 2.2e-07 31.3 6.2 9.3 2 2 4 6 6 6 2 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ60700.1 - 0.0061 16.2 20.9 0.0061 16.2 20.9 7.9 2 1 2 5 5 5 1 Spt20 family E1_dh PF00676.20 CDJ60702.1 - 1.2e-47 162.4 0.0 1.6e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 CDJ60702.1 - 9.5e-16 57.1 0.2 7.6e-15 54.2 0.1 2.2 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus ARID PF01388.21 CDJ60703.1 - 3.6e-12 46.8 0.0 3.6e-12 46.8 0.0 3.2 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain TFIIA PF03153.13 CDJ60703.1 - 0.0025 17.9 0.1 0.0025 17.9 0.1 9.5 3 3 5 9 9 9 1 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 CDJ60706.1 - 0.17 12.1 0.1 0.17 12.1 0.1 4.2 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) HD_assoc PF13286.6 CDJ60706.1 - 0.54 10.8 4.0 0.36 11.4 0.9 2.3 2 0 0 2 2 2 0 Phosphohydrolase-associated domain DEK_C PF08766.11 CDJ60709.1 - 2.1e-05 24.4 2.1 3.5e-05 23.6 2.1 1.4 1 0 0 1 1 1 1 DEK C terminal domain Nucleopor_Nup85 PF07575.13 CDJ60709.1 - 0.059 11.9 0.6 0.069 11.7 0.6 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin PhageMin_Tail PF10145.9 CDJ60709.1 - 0.061 13.2 0.4 0.088 12.6 0.4 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein Med8 PF10232.9 CDJ60709.1 - 0.081 12.5 5.7 0.11 12.1 5.7 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Sigma70_ner PF04546.13 CDJ60709.1 - 0.088 12.7 14.1 0.061 13.2 12.5 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Adaptin_binding PF10199.9 CDJ60709.1 - 0.14 12.8 9.0 0.19 12.3 9.0 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 GCIP PF13324.6 CDJ60709.1 - 0.22 11.1 5.1 0.28 10.8 5.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 CDJ60709.1 - 0.3 11.3 12.0 0.41 10.9 11.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3810 PF12725.7 CDJ60709.1 - 0.62 9.3 1.6 0.82 9.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Vfa1 PF08432.10 CDJ60709.1 - 2.7 8.3 10.5 3.6 7.9 10.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 CDJ60709.1 - 4.9 5.6 7.0 5.2 5.5 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ku_C PF03730.14 CDJ60709.1 - 6.3 7.6 10.5 10 6.9 10.5 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm CDC45 PF02724.14 CDJ60709.1 - 7.8 4.7 10.4 9 4.5 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Rad51 PF08423.11 CDJ60710.1 - 5.8e-114 379.6 0.0 8.7e-114 379.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CDJ60710.1 - 1.8e-11 44.0 0.1 2.4e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CDJ60710.1 - 4e-06 26.3 0.5 1.3e-05 24.7 0.5 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CDJ60710.1 - 4.3e-06 26.4 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDJ60710.1 - 0.00078 19.9 0.0 0.0022 18.4 0.0 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH_5 PF14520.6 CDJ60710.1 - 0.076 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DnaB_C PF03796.15 CDJ60710.1 - 0.15 11.3 0.2 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Adeno_VII PF03228.14 CDJ60711.1 - 0.27 11.9 0.9 0.66 10.6 0.1 1.9 2 1 0 2 2 2 0 Adenoviral core protein VII Peptidase_C48 PF02902.19 CDJ60712.1 - 1.1e-19 71.2 0.0 4.1e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Remorin_N PF03766.13 CDJ60712.1 - 0.029 14.4 0.1 0.12 12.4 0.1 2.1 1 0 0 1 1 1 0 Remorin, N-terminal region Ank_2 PF12796.7 CDJ60713.1 - 0.0025 18.3 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ60713.1 - 0.031 14.7 0.0 0.81 10.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 CDJ60713.1 - 0.2 12.3 0.1 2.9 8.6 0.1 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ60714.1 - 2.9e-15 56.6 0.1 7.7e-08 32.8 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDJ60714.1 - 2.6e-07 30.8 0.1 6.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDJ60714.1 - 0.0001 22.8 0.0 0.092 13.4 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDJ60714.1 - 0.0012 19.2 0.0 7.7 7.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDJ60714.1 - 0.0018 18.6 0.0 0.94 10.3 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeat Mpv17_PMP22 PF04117.12 CDJ60716.1 - 2.7e-11 43.5 0.5 2.7e-11 43.5 0.5 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Dpy19 PF10034.9 CDJ60716.1 - 0.00075 17.8 0.6 0.001 17.4 0.6 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Pex14_N PF04695.13 CDJ60716.1 - 0.0022 18.7 5.7 0.0022 18.7 5.7 3.4 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.9 CDJ60716.1 - 0.0041 17.3 6.9 0.046 13.9 0.6 2.3 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 CDJ60716.1 - 0.0094 15.4 5.3 0.28 10.6 0.6 2.1 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CDJ60716.1 - 0.0097 15.2 4.6 1.1 8.4 2.8 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Bac_export_2 PF01312.19 CDJ60716.1 - 0.0097 15.2 0.5 0.0097 15.2 0.5 2.2 2 0 0 2 2 2 1 FlhB HrpN YscU SpaS Family Connexin PF00029.19 CDJ60716.1 - 0.012 15.4 8.2 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 Connexin DUF4834 PF16118.5 CDJ60716.1 - 0.031 15.3 15.7 0.38 11.7 0.8 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) PXA PF02194.15 CDJ60716.1 - 0.18 11.8 11.0 0.76 9.7 5.0 2.2 2 0 0 2 2 2 0 PXA domain EPL1 PF10513.9 CDJ60716.1 - 0.22 11.9 13.5 0.1 13.0 3.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like SID-1_RNA_chan PF13965.6 CDJ60716.1 - 0.4 9.0 4.5 2.4 6.4 0.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 CDJ60716.1 - 0.47 10.6 9.4 2.6 8.2 3.0 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.20 CDJ60716.1 - 0.8 7.9 3.8 4.6 5.4 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CSG2 PF16965.5 CDJ60716.1 - 0.87 8.5 13.7 0.24 10.3 1.8 2.3 1 1 0 2 2 2 0 Ceramide synthase regulator EphA2_TM PF14575.6 CDJ60716.1 - 1.1 10.2 4.3 25 5.8 0.7 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 CDJ60716.1 - 1.2 8.8 6.9 6.2 6.5 1.5 2.4 2 0 0 2 2 2 0 FAM176 family SARAF PF06682.12 CDJ60716.1 - 1.3 8.6 18.3 1.6 8.3 5.5 2.7 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FAM60A PF15396.6 CDJ60716.1 - 1.5 8.8 6.9 1.8 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein Family FAM60A FHIPEP PF00771.20 CDJ60716.1 - 2.1 6.7 13.0 2.1 6.7 4.2 2.1 2 0 0 2 2 2 0 FHIPEP family DUF2149 PF09919.9 CDJ60716.1 - 2.5 8.4 5.0 1.6 9.0 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Exonuc_VII_L PF02601.15 CDJ60716.1 - 2.6 7.5 19.2 2.2 7.8 5.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit CLN3 PF02487.17 CDJ60716.1 - 3.1 6.7 11.9 5.8 5.8 1.5 2.5 2 0 0 2 2 2 0 CLN3 protein TERB2 PF15101.6 CDJ60716.1 - 3.5 7.6 21.9 1.7 8.7 7.5 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ALMT PF11744.8 CDJ60716.1 - 4 6.2 8.4 4.9 5.9 2.8 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3371 PF11851.8 CDJ60716.1 - 4.9 8.3 18.7 3.1 8.9 5.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) eIF-3_zeta PF05091.12 CDJ60716.1 - 5 6.0 18.0 0.88 8.5 3.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIF4E-T PF10477.9 CDJ60716.1 - 5 5.8 26.8 2.2 7.0 12.5 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FliP PF00813.20 CDJ60716.1 - 5.5 6.8 9.1 10 5.9 1.7 2.2 2 0 0 2 2 2 0 FliP family V_ATPase_I PF01496.19 CDJ60716.1 - 7.2 4.4 17.2 1.7 6.5 1.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Peroxin-13_N PF04088.13 CDJ60716.1 - 7.3 6.9 9.1 11 6.2 1.0 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Peptidase_S49_N PF08496.10 CDJ60716.1 - 7.4 6.6 11.0 15 5.6 0.2 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4746 PF15928.5 CDJ60716.1 - 7.6 5.9 8.7 4.1 6.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Folate_carrier PF01770.18 CDJ60716.1 - 7.7 5.1 12.3 0.66 8.7 1.5 2.1 2 0 0 2 2 2 0 Reduced folate carrier DUF2973 PF11189.8 CDJ60716.1 - 8.8 6.5 6.7 21 5.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Sporozoite_P67 PF05642.11 CDJ60716.1 - 9.5 4.2 10.7 0.11 10.6 3.2 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Kelch_4 PF13418.6 CDJ60717.1 - 3.7e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ60717.1 - 0.0001 22.4 0.0 0.00057 20.1 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CDJ60717.1 - 0.024 14.9 0.0 2.1 8.7 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain PAM2 PF07145.15 CDJ60717.1 - 0.025 14.3 0.2 0.062 13.0 0.2 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TraV PF09676.10 CDJ60717.1 - 0.052 14.5 0.2 0.052 14.5 0.2 11.4 5 3 4 9 9 9 0 Type IV conjugative transfer system lipoprotein (TraV) Kelch_1 PF01344.25 CDJ60717.1 - 0.1 12.2 0.0 0.42 10.2 0.0 2.1 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.6 CDJ60717.1 - 0.23 11.5 0.0 0.79 9.8 0.0 1.9 1 0 0 1 1 1 0 Kelch motif SPX PF03105.19 CDJ60718.1 - 0.00078 19.5 9.4 0.00078 19.5 9.4 2.6 2 1 0 2 2 2 1 SPX domain CDC45 PF02724.14 CDJ60718.1 - 0.008 14.5 13.3 0.055 11.8 7.3 2.5 2 0 0 2 2 2 2 CDC45-like protein Apt1 PF10351.9 CDJ60718.1 - 0.016 14.1 24.3 0.058 12.2 14.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cwf_Cwc_15 PF04889.12 CDJ60718.1 - 0.021 14.5 21.7 0.4 10.4 15.7 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 CDJ60718.1 - 0.75 8.5 14.7 0.52 9.0 7.1 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CDJ60718.1 - 0.8 9.2 30.2 1.1 8.7 4.5 2.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Mem_trans PF03547.18 CDJ60718.1 - 2.7 6.3 8.1 0.1 11.0 0.8 2.2 2 0 0 2 2 2 0 Membrane transport protein Sin_N PF04801.13 CDJ60718.1 - 2.8 7.1 26.2 4 6.6 5.3 2.6 2 0 0 2 2 2 0 Sin-like protein conserved region Peptidase_S49_N PF08496.10 CDJ60718.1 - 3.6 7.6 16.8 12 5.9 8.8 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.11 CDJ60718.1 - 4.6 6.6 19.9 2.1 7.7 12.3 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Hid1 PF12722.7 CDJ60718.1 - 5.8 4.9 22.1 0.56 8.3 11.1 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein MAT1 PF06391.13 CDJ60718.1 - 6.5 6.5 28.8 0.54 10.1 2.7 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 ESM4 PF15952.5 CDJ60718.1 - 7.4 7.0 29.3 3.2 8.2 13.8 2.4 2 0 0 2 2 2 0 Enhancer of split M4 family RskA PF10099.9 CDJ60719.1 - 0.00059 20.2 0.5 0.00059 20.2 0.5 3.8 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ60719.1 - 0.16 10.6 37.8 0.18 10.4 37.8 1.1 1 0 0 1 1 1 0 Hamartin protein VIR_N PF15912.5 CDJ60719.1 - 0.7 9.4 26.5 0.072 12.7 11.0 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal DUF2722 PF10846.8 CDJ60720.1 - 0.0046 16.0 7.8 0.0046 16.0 7.8 6.4 4 2 1 5 5 5 2 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 CDJ60721.1 - 0.0073 15.8 3.7 0.0073 15.8 3.7 3.3 3 0 0 3 3 3 1 Plasmodium vivax Vir protein Shadoo PF14999.6 CDJ60721.1 - 0.0097 16.0 1.2 0.0097 16.0 1.2 4.5 4 1 0 4 4 4 2 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.19 CDJ60721.1 - 0.028 15.0 2.5 0.028 15.0 2.5 6.7 4 1 2 6 6 6 0 60s Acidic ribosomal protein Utp14 PF04615.13 CDJ60721.1 - 0.41 9.2 53.4 0.17 10.4 28.7 2.1 2 0 0 2 2 2 0 Utp14 protein TFIIA PF03153.13 CDJ60722.1 - 0.046 13.7 31.2 0.06 13.3 31.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 CDJ60722.1 - 0.22 11.4 21.2 0.02 14.8 16.1 1.7 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF3391 PF11871.8 CDJ60723.1 - 0.071 13.6 0.4 0.071 13.6 0.4 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) SOUL PF04832.12 CDJ60724.1 - 3.8e-30 105.3 0.0 2e-23 83.4 0.0 2.0 2 0 0 2 2 2 2 SOUL heme-binding protein Pkinase PF00069.25 CDJ60726.1 - 3.9e-77 259.2 0.0 5.4e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60726.1 - 5.1e-36 124.3 0.0 8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDJ60726.1 - 2.6e-30 101.7 3.5 1.9e-07 30.2 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDJ60726.1 - 3e-24 85.2 1.2 2.5e-11 43.9 0.0 3.4 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60726.1 - 1.5e-23 80.6 0.4 3.1e-06 26.7 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDJ60726.1 - 1.2e-21 75.2 3.9 4.5e-06 25.9 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDJ60726.1 - 4.2e-19 68.1 7.2 8.9e-09 35.1 0.4 4.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CDJ60726.1 - 1.5e-06 28.1 0.6 0.012 15.6 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 CDJ60726.1 - 2.6e-05 23.7 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 CDJ60726.1 - 3.9e-05 23.9 0.0 0.02 15.2 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 CDJ60726.1 - 8.2e-05 22.1 0.0 0.0008 18.8 0.0 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDJ60726.1 - 0.00012 22.0 0.0 0.014 15.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_9 PF14658.6 CDJ60726.1 - 0.00027 21.2 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF2267 PF10025.9 CDJ60726.1 - 0.002 18.4 0.0 0.28 11.5 0.0 3.0 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2267) Peptidase_S8 PF00082.22 CDJ60727.1 - 1.5e-33 116.3 0.2 1.5e-33 116.3 0.2 6.5 5 2 0 5 5 5 1 Subtilase family adh_short_C2 PF13561.6 CDJ60728.1 - 5.3e-38 130.9 0.0 6.6e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Enoyl_reductase PF12241.8 CDJ60728.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Es2 PF09751.9 CDJ60729.1 - 2.4e-07 30.9 40.1 1.5e-05 25.0 23.7 5.5 2 2 2 4 4 4 2 Nuclear protein Es2 Totivirus_coat PF05518.11 CDJ60730.1 - 0.11 10.5 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein YbjQ_1 PF01906.17 CDJ60731.1 - 4.6e-18 65.8 0.0 6.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding PNP_UDP_1 PF01048.20 CDJ60732.1 - 1.1e-11 44.4 0.2 1.2e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CDP-OH_P_transf PF01066.21 CDJ60733.1 - 8.2e-14 52.1 0.1 8.2e-14 52.1 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_L32e PF01655.18 CDJ60734.1 - 2.4e-45 153.4 0.6 2.4e-45 153.4 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L32 pPIWI_RE_X PF13111.6 CDJ60734.1 - 0.029 13.6 0.5 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 pPIWI_RE module N-terminal domain LCCL PF03815.19 CDJ60735.1 - 2.8e-36 123.5 0.2 2e-16 59.9 0.0 4.5 3 1 1 4 4 4 4 LCCL domain SRCR PF00530.18 CDJ60735.1 - 3.4e-06 27.5 3.6 0.012 16.0 1.0 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Rtf2 PF04641.12 CDJ60736.1 - 5.9 6.2 14.5 6.7 6.0 14.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.6 CDJ60736.1 - 6 6.8 11.5 7.4 6.5 11.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GRAM PF02893.20 CDJ60737.1 - 1.7e-11 44.0 2.2 3.9e-09 36.4 2.2 2.8 1 1 0 1 1 1 1 GRAM domain DUF1081 PF06448.11 CDJ60737.1 - 0.53 10.7 0.0 0.53 10.7 0.0 4.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1081) ETRAMP PF09716.10 CDJ60737.1 - 1.4 9.0 0.0 1.4 9.0 0.0 7.8 9 0 0 9 9 9 0 Malarial early transcribed membrane protein (ETRAMP) Syntaxin PF00804.25 CDJ60738.1 - 2.2e-20 73.2 10.9 2.2e-20 73.2 10.9 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CDJ60738.1 - 7.7e-10 38.6 1.5 7.7e-10 38.6 1.5 1.8 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 CDJ60738.1 - 0.0027 17.6 2.6 0.025 14.4 0.5 2.3 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4577 PF15145.6 CDJ60738.1 - 0.023 14.7 0.2 0.067 13.2 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4577) DUF846 PF05832.12 CDJ60738.1 - 0.066 13.2 0.1 0.099 12.7 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) MCU PF04678.13 CDJ60738.1 - 0.18 11.9 12.4 0.87 9.7 1.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Sigma54_AID PF00309.20 CDJ60738.1 - 0.21 11.5 11.8 0.57 10.1 11.8 1.8 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) AKNA PF12443.8 CDJ60738.1 - 0.32 11.7 5.8 9.9 6.9 0.3 2.9 2 1 0 2 2 2 0 AT-hook-containing transcription factor LMBR1 PF04791.16 CDJ60738.1 - 0.92 8.3 6.1 1.2 8.0 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mit_KHE1 PF10173.9 CDJ60738.1 - 1.2 9.2 6.9 3.3 7.7 0.4 2.4 1 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF1515 PF07439.11 CDJ60738.1 - 2 8.5 6.8 0.15 12.1 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) SUIM_assoc PF16619.5 CDJ60739.1 - 0.3 11.2 65.6 0.22 11.6 14.3 5.6 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 DUF4064 PF13273.6 CDJ60739.1 - 4.1 7.7 5.8 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) SPT6_acidic PF14632.6 CDJ60739.1 - 6.6 7.4 8.0 0.57 10.8 0.8 2.6 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Profilin PF00235.19 CDJ60740.1 - 5.1e-16 59.1 1.3 9.4e-16 58.2 1.3 1.4 1 1 0 1 1 1 1 Profilin Kinase-like PF14531.6 CDJ60741.1 - 0.0036 16.7 0.0 0.022 14.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 CDJ60744.1 - 0.012 15.7 1.1 0.012 15.7 1.1 11.6 11 2 1 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 DUF1612 PF07756.12 CDJ60744.1 - 0.18 12.1 2.4 0.35 11.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Pkinase PF00069.25 CDJ60745.1 - 7.4e-25 87.8 0.0 9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60745.1 - 3.8e-16 59.2 0.0 4.7e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ60745.1 - 1.7e-08 33.6 0.0 2.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF3626 PF12294.8 CDJ60746.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3626) DUF3626 PF12294.8 CDJ60747.1 - 0.0081 15.2 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) Chlam_OMP PF01308.17 CDJ60748.1 - 0.0079 15.0 2.3 0.014 14.2 2.3 1.3 1 0 0 1 1 1 1 Chlamydia major outer membrane protein SET PF00856.28 CDJ60748.1 - 0.012 16.1 0.1 0.17 12.3 0.1 2.4 2 1 0 2 2 2 0 SET domain TPR_2 PF07719.17 CDJ60748.1 - 0.025 14.7 3.9 3.2 8.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ60748.1 - 0.25 11.9 3.4 0.15 12.6 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ60748.1 - 1.8 9.6 15.2 0.5 11.3 3.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ60748.1 - 7.2 7.4 16.3 7.5 7.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IspD PF01128.19 CDJ60750.1 - 6.3e-17 62.1 12.4 1.2e-13 51.4 2.8 4.5 4 1 0 5 5 5 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase OmpH PF03938.14 CDJ60750.1 - 0.85 10.0 68.0 3.4 8.0 14.5 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DHHA1 PF02272.19 CDJ60750.1 - 5.5 7.4 5.4 4 7.8 1.1 2.6 2 0 0 2 2 2 0 DHHA1 domain SUIM_assoc PF16619.5 CDJ60751.1 - 0.00074 19.5 1.0 0.00074 19.5 1.0 2.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 CDJ60751.1 - 0.002 18.1 25.4 0.12 12.3 5.0 2.2 2 0 0 2 2 2 2 SPX domain RskA PF10099.9 CDJ60751.1 - 0.0022 18.3 3.1 0.0022 18.3 3.1 3.5 3 0 0 3 3 3 1 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ60751.1 - 0.0031 17.2 6.0 0.0031 17.2 6.0 2.5 2 0 0 2 2 2 1 Spt20 family TLP-20 PF06088.11 CDJ60751.1 - 7.6 6.4 9.4 3.2 7.6 2.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1764 PF08576.10 CDJ60752.1 - 1.4e-09 38.7 7.4 1.4e-09 38.7 7.4 2.9 1 1 1 2 2 1 1 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.9 CDJ60752.1 - 0.013 15.1 39.3 0.049 13.2 39.3 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein IL5 PF02025.15 CDJ60752.1 - 0.06 13.6 2.8 0.099 12.9 2.8 1.3 1 0 0 1 1 1 0 Interleukin 5 GEMIN8 PF15348.6 CDJ60752.1 - 0.13 12.5 18.4 0.2 11.9 18.4 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SOG2 PF10428.9 CDJ60752.1 - 0.27 10.4 23.0 0.33 10.1 23.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein YL1 PF05764.13 CDJ60752.1 - 0.28 11.3 31.6 0.37 10.9 31.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein REV PF00424.18 CDJ60752.1 - 0.49 10.4 5.9 4.6 7.3 0.3 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Cwf_Cwc_15 PF04889.12 CDJ60752.1 - 0.61 9.8 30.2 0.85 9.3 30.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SRP-alpha_N PF04086.13 CDJ60752.1 - 2.7 7.8 32.8 3.9 7.3 32.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SMYLE_N PF18615.1 CDJ60752.1 - 5 6.6 19.9 6.9 6.1 19.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CAC1F_C PF16885.5 CDJ60752.1 - 7.4 6.1 19.6 9.2 5.8 19.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Ndc1_Nup PF09531.10 CDJ60752.1 - 8.4 5.0 23.8 9.4 4.8 23.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_10 PF13374.6 CDJ60753.1 - 0.00052 19.8 0.3 0.00052 19.8 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60753.1 - 0.0014 18.3 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60753.1 - 0.013 15.6 0.0 7.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat FH2 PF02181.23 CDJ60754.1 - 3e-15 56.2 0.2 3e-15 56.2 0.2 2.1 3 0 0 3 3 3 1 Formin Homology 2 Domain AAA_23 PF13476.6 CDJ60754.1 - 1.5 9.2 10.3 1.1 9.7 0.9 2.4 2 0 0 2 2 2 0 AAA domain RNB PF00773.19 CDJ60755.1 - 3.2e-26 92.4 23.0 2.2e-14 53.5 0.0 5.5 5 1 0 6 6 6 3 RNB domain DUF2722 PF10846.8 CDJ60755.1 - 0.0015 17.5 3.1 0.0015 17.5 3.1 12.7 9 2 0 11 11 11 4 Protein of unknown function (DUF2722) MAPKK1_Int PF08923.10 CDJ60756.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting eIF3_subunit PF08597.10 CDJ60758.1 - 0.006 16.5 8.7 0.006 16.5 8.7 4.2 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit PseudoU_synth_2 PF00849.22 CDJ60759.1 - 2.9e-21 76.2 0.1 2.9e-21 76.2 0.1 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase USP7_ICP0_bdg PF12436.8 CDJ60759.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 RskA PF10099.9 CDJ60759.1 - 0.064 13.5 0.0 0.064 13.5 0.0 27.2 12 9 5 18 18 18 0 Anti-sigma-K factor rskA NARP1 PF12569.8 CDJ60760.1 - 1.2e-94 318.1 15.1 5.4e-62 210.4 10.1 4.6 2 1 1 4 4 4 4 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 CDJ60760.1 - 2e-05 24.6 0.4 0.01 16.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ60760.1 - 4.6e-05 23.9 8.8 0.56 11.2 0.0 7.0 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDJ60760.1 - 0.00011 21.5 0.8 0.0012 18.1 0.0 2.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60760.1 - 0.0033 17.4 6.5 0.27 11.3 0.1 5.4 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60760.1 - 0.0039 17.3 8.2 6.8 7.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60760.1 - 0.013 15.5 8.5 6 7.2 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ60760.1 - 0.017 15.4 10.7 0.31 11.3 1.2 4.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60760.1 - 0.031 14.1 6.1 38 4.3 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ60760.1 - 0.045 14.3 5.1 12 6.5 0.0 4.2 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ60760.1 - 4.1 8.2 8.4 50 4.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Thiolase_N PF00108.23 CDJ60761.1 - 5.4e-19 68.6 0.0 3.5e-08 33.1 0.0 2.4 3 0 0 3 3 3 2 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CDJ60761.1 - 0.012 15.4 0.7 0.031 14.1 0.2 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Tox-ODYAM1 PF15642.6 CDJ60761.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus RDM PF11002.8 CDJ60763.1 - 0.11 12.5 0.5 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 RFPL defining motif (RDM) DUF4332 PF14229.6 CDJ60766.1 - 0.0082 16.4 0.3 9.4 6.5 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4332) zf-Paramyx-P PF13008.7 CDJ60766.1 - 0.11 11.9 0.1 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Nup_retrotrp_bd PF10599.9 CDJ60767.1 - 0.027 15.1 3.7 0.077 13.7 3.7 1.9 1 1 0 1 1 1 0 Retro-transposon transporting motif TFIIF_alpha PF05793.12 CDJ60767.1 - 0.81 8.2 32.8 1.1 7.7 32.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.13 CDJ60767.1 - 3.1 7.3 30.2 4.1 6.9 30.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RskA PF10099.9 CDJ60769.1 - 8.6e-08 32.7 16.0 5e-05 23.7 13.6 10.5 4 2 5 10 10 10 4 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ60769.1 - 2.4e-05 24.1 15.0 2.4e-05 24.1 15.0 14.0 11 2 0 12 12 12 2 Nuclear RNA-splicing-associated protein Otopetrin PF03189.13 CDJ60769.1 - 0.33 9.7 12.5 77 1.9 11.9 4.3 1 1 0 1 1 1 0 Otopetrin Abhydrolase_3 PF07859.13 CDJ60772.1 - 0.00013 22.0 0.1 0.0003 20.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CDJ60772.1 - 0.00073 18.5 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF3678 PF12435.8 CDJ60772.1 - 0.009 15.4 1.2 0.026 13.9 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) BPL_LplA_LipB PF03099.19 CDJ60773.1 - 4.8e-10 39.4 0.2 9.9e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CDJ60773.1 - 0.0054 16.6 0.8 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain Neur_chan_memb PF02932.16 CDJ60774.1 - 3.8 7.5 6.2 21 5.1 0.3 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region REF PF05755.12 CDJ60774.1 - 4.8 6.9 6.1 1 9.2 2.3 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Spt20 PF12090.8 CDJ60777.1 - 0.00022 20.9 18.4 0.00022 20.9 18.4 8.4 6 1 2 8 8 8 4 Spt20 family Sporozoite_P67 PF05642.11 CDJ60777.1 - 0.0038 15.4 1.2 0.0038 15.4 1.2 4.8 5 1 0 5 5 5 2 Sporozoite P67 surface antigen Ribosomal_S28e PF01200.18 CDJ60778.1 - 1.3e-31 108.3 1.9 1.5e-31 108.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e GDPD PF03009.17 CDJ60779.1 - 1.3e-06 28.3 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Mitofilin PF09731.9 CDJ60779.1 - 0.36 9.6 8.3 0.46 9.3 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CRAL_TRIO PF00650.20 CDJ60780.1 - 0.0008 19.2 0.1 0.0063 16.2 0.0 1.9 1 1 1 2 2 2 2 CRAL/TRIO domain DOT1 PF08123.13 CDJ60781.1 - 0.00042 19.9 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 CDJ60781.1 - 0.0039 16.6 0.8 0.0087 15.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RIBIOP_C PF04950.12 CDJ60782.1 - 6.1e-34 117.8 0.0 9.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDJ60782.1 - 9.9e-07 28.8 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CCDC66 PF15236.6 CDJ60783.1 - 0.011 15.5 20.5 0.033 14.0 20.5 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 EGF_CA PF07645.15 CDJ60787.1 - 5.8e-09 36.0 7.7 5.8e-09 36.0 7.7 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CDJ60787.1 - 8.8e-06 25.5 14.9 0.017 15.0 4.6 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like Notch PF00066.17 CDJ60787.1 - 7.6e-05 23.1 2.5 0.00026 21.4 2.5 1.9 1 0 0 1 1 1 1 LNR domain EGF_3 PF12947.7 CDJ60787.1 - 0.00015 21.9 8.3 0.00015 21.9 8.3 2.6 2 0 0 2 2 2 1 EGF domain FXa_inhibition PF14670.6 CDJ60787.1 - 0.0014 18.9 7.9 0.0014 18.9 7.9 3.4 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDJ60787.1 - 0.0018 18.5 2.6 0.0018 18.5 2.6 3.5 2 1 1 3 3 3 2 EGF-like domain EGF_MSP1_1 PF12946.7 CDJ60787.1 - 3.6 7.7 13.4 0.54 10.4 3.8 2.5 2 0 0 2 2 2 0 MSP1 EGF domain 1 Peptidase_C11 PF03415.14 CDJ60788.1 - 2.2e-07 30.6 0.0 5.6e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 Clostripain family PHA-1 PF06542.11 CDJ60788.1 - 0.23 10.2 0.0 0.51 9.1 0.0 1.5 2 0 0 2 2 2 0 Regulator protein PHA-1 CBM_20 PF00686.19 CDJ60789.1 - 5.3e-12 45.5 0.0 5.3e-12 45.5 0.0 2.1 2 1 0 2 2 2 1 Starch binding domain DUF913 PF06025.12 CDJ60789.1 - 0.0052 15.8 0.6 0.0052 15.8 0.6 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF2722 PF10846.8 CDJ60789.1 - 0.037 13.0 0.1 0.037 13.0 0.1 3.0 2 1 1 3 3 1 0 Protein of unknown function (DUF2722) Serinc PF03348.15 CDJ60789.1 - 0.057 12.3 1.4 0.072 12.0 1.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1345 PF07077.11 CDJ60789.1 - 0.071 12.8 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) CLN3 PF02487.17 CDJ60789.1 - 0.38 9.8 8.9 0.63 9.0 8.9 1.3 1 0 0 1 1 1 0 CLN3 protein PUNUT PF16913.5 CDJ60789.1 - 0.54 9.4 3.8 0.79 8.9 0.9 2.2 2 1 1 3 3 3 0 Purine nucleobase transmembrane transport V_ATPase_I PF01496.19 CDJ60789.1 - 1.2 6.9 18.2 0.1 10.5 13.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CDJ60789.1 - 1.3 7.7 4.7 1.9 7.2 4.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein INSIG PF07281.12 CDJ60789.1 - 2.7 7.6 6.5 0.84 9.2 3.7 1.6 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) RR_TM4-6 PF06459.12 CDJ60789.1 - 2.9 7.7 16.1 0.11 12.3 10.4 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 CDJ60789.1 - 4.9 5.1 14.0 7.1 4.6 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 CDJ60789.1 - 5.3 5.3 5.1 7.1 4.9 5.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 CDJ60789.1 - 8.8 5.4 7.3 14 4.8 7.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Rad4 PF03835.15 CDJ60790.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 4.1 4 0 0 4 4 4 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CDJ60790.1 - 0.42 11.1 0.0 0.42 11.1 0.0 5.0 5 0 0 5 5 5 0 Transglutaminase-like superfamily Spt20 PF12090.8 CDJ60791.1 - 0.0019 17.9 7.4 0.0019 17.9 7.4 11.2 9 2 0 9 9 9 6 Spt20 family RPAP1_C PF08620.10 CDJ60792.1 - 2.1e-19 69.4 0.2 8.6e-19 67.4 0.2 2.2 1 0 0 1 1 1 1 RPAP1-like, C-terminal Peptidase_M16_C PF05193.21 CDJ60793.1 - 7.7e-09 35.8 0.0 2.1e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 CDJ60793.1 - 2.1 7.4 6.4 4.2 6.4 6.4 1.5 1 0 0 1 1 1 0 Peptidase M16C associated HECT PF00632.25 CDJ60794.1 - 2.9e-06 27.0 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CDJ60794.1 - 3.8e-05 23.8 0.1 0.00041 20.4 0.1 3.0 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 CDJ60794.1 - 0.00029 21.0 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 CDJ60794.1 - 0.36 10.8 2.5 0.91 9.5 0.1 2.8 2 0 0 2 2 2 0 UBA/TS-N domain RskA PF10099.9 CDJ60796.1 - 3.2e-05 24.3 7.2 5.7e-05 23.5 7.2 1.4 1 1 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ60796.1 - 0.033 13.8 9.5 0.041 13.5 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ETRAMP PF09716.10 CDJ60796.1 - 0.39 10.8 1.8 1.3 9.2 0.2 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) BAF1_ABF1 PF04684.13 CDJ60796.1 - 0.6 9.1 22.5 0.66 9.0 22.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SWI-SNF_Ssr4 PF08549.10 CDJ60796.1 - 2.5 6.6 22.8 2.7 6.5 22.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PIP5K PF01504.18 CDJ60796.1 - 2.5 7.2 12.7 3.3 6.8 12.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Trp_oprn_chp PF09534.10 CDJ60796.1 - 3.1 7.6 11.2 5.1 6.9 11.0 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BRF1 PF07741.13 CDJ60796.1 - 3.4 8.0 15.1 7.3 7.0 1.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Pex14_N PF04695.13 CDJ60796.1 - 4.7 7.8 33.6 0.23 12.1 12.8 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.6 CDJ60796.1 - 4.9 5.4 9.0 6.1 5.1 9.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_tran_10_N PF17039.5 CDJ60796.1 - 5 7.6 10.0 20 5.7 10.0 1.9 1 1 0 1 1 1 0 Fucosyltransferase, N-terminal Dishevelled PF02377.15 CDJ60796.1 - 5.2 7.5 15.5 9.7 6.6 15.5 1.5 1 1 0 1 1 1 0 Dishevelled specific domain Draxin PF15550.6 CDJ60796.1 - 6.2 6.6 14.3 7.1 6.4 14.3 1.2 1 0 0 1 1 1 0 Draxin Hydin_ADK PF17213.3 CDJ60796.1 - 8.4 6.6 20.5 13 6.0 20.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SARAF PF06682.12 CDJ60796.1 - 8.7 5.9 17.4 10 5.6 17.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Maf1 PF09174.10 CDJ60796.1 - 9.9 6.3 23.4 0.15 12.2 7.8 2.0 1 1 1 2 2 2 0 Maf1 regulator DUF2722 PF10846.8 CDJ60798.1 - 6.5e-05 22.1 9.7 7e-05 22.0 9.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF898 PF05987.13 CDJ60798.1 - 0.062 12.4 4.5 0.076 12.1 4.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) MMR1 PF08505.10 CDJ60798.1 - 0.067 13.5 7.3 0.069 13.4 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Spore_YhcN_YlaJ PF09580.10 CDJ60798.1 - 0.073 13.2 7.1 0.095 12.8 7.1 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) EPL1 PF10513.9 CDJ60798.1 - 0.076 13.4 3.6 0.075 13.4 3.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Nramp PF01566.18 CDJ60798.1 - 0.093 11.7 16.8 0.12 11.4 16.8 1.0 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein PEHE PF15275.6 CDJ60798.1 - 0.12 13.1 7.0 0.14 12.8 7.0 1.1 1 0 0 1 1 1 0 PEHE domain Roughex PF06020.11 CDJ60798.1 - 0.14 11.2 11.3 0.17 10.9 11.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CSG2 PF16965.5 CDJ60798.1 - 0.38 9.6 2.4 0.49 9.3 2.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MPM1 PF17234.2 CDJ60798.1 - 0.48 10.7 7.6 0.63 10.3 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Presenilin PF01080.17 CDJ60798.1 - 0.52 9.0 8.0 0.57 8.9 8.0 1.2 1 0 0 1 1 1 0 Presenilin AF-4 PF05110.13 CDJ60798.1 - 0.67 8.0 12.9 0.76 7.8 12.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SID-1_RNA_chan PF13965.6 CDJ60798.1 - 1.3 7.4 2.7 1.5 7.1 2.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spt20 PF12090.8 CDJ60798.1 - 1.6 8.3 29.0 2.1 7.9 29.0 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_M56 PF05569.11 CDJ60798.1 - 1.8 7.7 5.9 0.88 8.7 4.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 eIF-3_zeta PF05091.12 CDJ60798.1 - 2.1 7.3 11.0 2.5 7.0 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0524 PF15823.5 CDJ60798.1 - 2.6 7.4 7.1 4 6.8 7.1 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 TERB2 PF15101.6 CDJ60798.1 - 2.6 8.0 13.6 3.8 7.5 13.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 WBP-1 PF11669.8 CDJ60798.1 - 2.6 8.7 6.9 4.6 7.9 6.9 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 XRN_M PF17846.1 CDJ60798.1 - 3.4 6.5 5.7 3.7 6.4 5.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain TMEM51 PF15345.6 CDJ60798.1 - 3.6 7.4 14.8 4.2 7.1 14.8 1.2 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4834 PF16118.5 CDJ60798.1 - 4.1 8.4 12.6 7.3 7.6 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PAT1 PF09770.9 CDJ60798.1 - 5 5.3 17.8 5.3 5.2 17.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 CDJ60798.1 - 5.7 6.6 9.9 0.84 9.4 6.3 1.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0560 PF10577.9 CDJ60798.1 - 5.7 5.3 13.0 6.7 5.1 13.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FSA_C PF10479.9 CDJ60798.1 - 8 4.5 13.8 9.8 4.2 13.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hid1 PF12722.7 CDJ60798.1 - 8.2 4.4 9.6 8.5 4.4 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CDJ60798.1 - 9.2 3.2 12.6 9.9 3.1 12.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1192 PF06698.11 CDJ60799.1 - 0.028 14.4 1.0 0.028 14.4 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FAM76 PF16046.5 CDJ60799.1 - 0.036 13.4 26.0 0.052 12.9 2.4 3.1 3 0 0 3 3 3 0 FAM76 protein FapA PF03961.13 CDJ60799.1 - 0.37 9.4 12.2 0.022 13.4 2.4 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A RAP1 PF07218.11 CDJ60799.1 - 2 6.6 14.3 1.5 7.0 2.7 2.3 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Fcf1 PF04900.12 CDJ60800.1 - 2e-05 24.9 0.1 2e-05 24.9 0.1 2.7 2 0 0 2 2 2 1 Fcf1 BUD22 PF09073.10 CDJ60800.1 - 0.0041 16.5 8.5 0.0041 16.5 8.5 3.4 3 0 0 3 3 3 1 BUD22 DUF4718 PF15842.5 CDJ60800.1 - 0.0049 16.7 9.6 0.0049 16.7 9.6 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4718) TFIIA PF03153.13 CDJ60800.1 - 0.096 12.7 80.4 0.2 11.6 30.0 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.8 CDJ60800.1 - 9.5 6.2 21.4 29 4.6 21.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SUIM_assoc PF16619.5 CDJ60801.1 - 0.0003 20.8 3.2 0.0003 20.8 3.2 8.3 4 2 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ60801.1 - 0.00048 19.8 8.8 0.00048 19.8 8.8 4.5 3 2 0 3 3 3 1 Spt20 family DUF2722 PF10846.8 CDJ60801.1 - 0.0056 15.7 7.7 0.0056 15.7 7.7 4.6 3 2 1 4 4 4 2 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ60801.1 - 0.14 12.4 76.5 0.14 12.5 5.8 5.1 2 2 2 4 4 4 0 Anti-sigma-K factor rskA EOS1 PF12326.8 CDJ60801.1 - 1.2 9.1 15.8 6.4 6.7 0.4 3.3 3 0 0 3 3 3 0 N-glycosylation protein DUF5081 PF16887.5 CDJ60801.1 - 1.5 7.9 6.9 0.12 11.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5081) eIF-3_zeta PF05091.12 CDJ60801.1 - 3.2 6.6 33.6 2.5 7.0 1.2 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TCP PF03634.13 CDJ60801.1 - 8.4 6.9 47.7 0.075 13.6 8.3 3.5 3 1 0 3 3 3 0 TCP family transcription factor SPX PF03105.19 CDJ60802.1 - 0.047 13.6 16.2 0.055 13.4 16.2 1.0 1 0 0 1 1 1 0 SPX domain SARAF PF06682.12 CDJ60802.1 - 0.97 9.0 10.5 1.2 8.7 10.5 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RskA PF10099.9 CDJ60802.1 - 2.7 8.3 11.9 1.8 8.8 1.1 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Apt1 PF10351.9 CDJ60802.1 - 5 5.8 17.9 5.6 5.7 17.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2722 PF10846.8 CDJ60804.1 - 5.2e-05 22.4 0.7 5.2e-05 22.4 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF1730 PF08331.10 CDJ60804.1 - 0.018 15.0 0.5 0.04 13.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) ThylakoidFormat PF11264.8 CDJ60804.1 - 0.021 14.5 0.2 0.021 14.5 0.2 1.6 2 0 0 2 2 2 0 Thylakoid formation protein Hep_59 PF07052.11 CDJ60804.1 - 0.11 13.2 5.8 0.16 12.7 0.3 3.0 3 1 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 TFIIA PF03153.13 CDJ60804.1 - 1.2 9.1 26.3 0.18 11.8 22.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nbs1_C PF08599.10 CDJ60804.1 - 6.7 6.9 7.3 14 5.9 7.3 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Vac14_Fig4_bd PF11916.8 CDJ60805.1 - 1.8e-37 128.7 0.1 8.1e-37 126.6 0.1 2.0 1 1 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CDJ60805.1 - 7.9e-31 106.5 0.0 2.7e-28 98.4 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDJ60805.1 - 1.7e-11 43.3 0.3 0.021 15.0 0.0 5.6 4 0 0 4 4 4 3 HEAT repeat Tti2 PF10521.9 CDJ60805.1 - 0.003 17.1 3.2 2 7.9 0.0 3.6 3 1 0 3 3 3 2 Tti2 family HEAT_EZ PF13513.6 CDJ60805.1 - 0.64 10.6 0.0 0.64 10.6 0.0 7.0 8 0 0 8 8 8 0 HEAT-like repeat PPR PF01535.20 CDJ60806.1 - 1.7e-12 46.7 4.2 0.012 15.8 0.2 6.1 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 CDJ60806.1 - 1.4e-11 44.4 0.0 2e-05 24.7 0.0 4.5 5 1 1 6 6 6 2 PPR repeat family PPR_long PF17177.4 CDJ60806.1 - 1.6e-08 34.2 0.0 1.6e-08 34.2 0.0 3.7 2 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CDJ60806.1 - 0.00076 19.5 0.0 5.8 7.1 0.0 5.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain TPR_3 PF07720.12 CDJ60806.1 - 0.02 14.9 0.3 0.36 10.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60806.1 - 0.026 14.5 11.9 0.066 13.3 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ60806.1 - 0.035 13.9 0.2 0.035 13.9 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60806.1 - 0.31 11.3 0.1 0.31 11.3 0.1 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 CDJ60806.1 - 6.4 6.6 5.1 8.1 6.2 0.2 3.1 4 0 0 4 4 4 0 PPR repeat SF3A2 PF16835.5 CDJ60807.1 - 1.2e-35 121.7 0.0 1.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDJ60807.1 - 3.1e-07 30.6 1.4 6.4e-07 29.6 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CDJ60807.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Antistasin PF02822.14 CDJ60808.1 - 0.15 12.7 5.3 0.24 12.1 5.3 1.3 1 0 0 1 1 1 0 Antistasin family BAF1_ABF1 PF04684.13 CDJ60808.1 - 5.3 6.0 25.0 6.5 5.7 25.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CRAL_TRIO PF00650.20 CDJ60809.1 - 0.00021 21.1 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Doppel PF11466.8 CDJ60809.1 - 0.14 11.8 2.6 0.85 9.3 0.6 2.3 2 0 0 2 2 2 0 Prion-like protein Doppel ART-PolyVal PF18760.1 CDJ60811.1 - 0.041 14.9 0.9 0.11 13.6 0.9 1.6 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins CDC48_2 PF02933.17 CDJ60811.1 - 0.084 12.7 0.2 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 Plasmodium_Vir PF05795.11 CDJ60811.1 - 0.43 9.9 4.2 0.98 8.8 4.2 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.12 CDJ60811.1 - 2.9 6.8 5.8 0.46 9.4 1.6 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MID_MedPIWI PF18296.1 CDJ60811.1 - 5.9 6.6 9.9 2.5 7.8 3.6 2.4 2 0 0 2 2 2 0 MID domain of medPIWI SNARE_assoc PF09335.11 CDJ60812.1 - 9e-16 58.4 8.2 8.4e-15 55.3 6.0 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3087 PF11286.8 CDJ60812.1 - 0.3 10.5 0.7 0.9 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) PARG_cat PF05028.14 CDJ60813.1 - 1.6e-81 274.2 0.0 2.5e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) FAD_binding_4 PF01565.23 CDJ60814.1 - 1.5e-30 105.7 0.7 2.8e-30 104.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 CDJ60814.1 - 8.1e-18 65.0 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Surface_antigen PF11054.8 CDJ60815.1 - 2.7e-30 105.8 0.6 3.5e-30 105.5 0.6 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen ubiquitin PF00240.23 CDJ60816.1 - 2.6e-34 116.8 0.3 3.6e-34 116.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDJ60816.1 - 5.9e-30 102.9 11.2 9e-30 102.3 11.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDJ60816.1 - 6.8e-17 61.1 0.5 1e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDJ60816.1 - 3.3e-06 27.5 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDJ60816.1 - 0.004 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDJ60816.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDJ60816.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDJ60816.1 - 0.025 14.6 0.8 5.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDJ60816.1 - 0.044 14.4 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain TPR_1 PF00515.28 CDJ60817.1 - 1.8e-13 49.7 5.0 3.7e-05 23.4 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ60817.1 - 3e-12 45.7 5.8 0.00019 21.3 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60817.1 - 6.4e-08 32.2 5.9 0.0078 16.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ60817.1 - 5.5e-07 29.2 3.6 0.062 13.0 0.0 3.8 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.6 CDJ60817.1 - 5.9e-06 26.5 6.5 0.033 14.5 0.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ60817.1 - 7.2e-06 26.6 10.6 3.1e-05 24.5 1.6 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ60817.1 - 8.9e-06 25.8 0.7 1.5e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDJ60817.1 - 0.00018 21.6 0.4 0.00018 21.6 0.4 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ60817.1 - 0.0086 16.6 4.1 0.028 14.9 2.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ60817.1 - 0.014 15.7 0.3 6.7 7.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_17 PF12728.7 CDJ60817.1 - 0.016 15.4 1.1 0.048 13.9 0.6 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_14 PF13428.6 CDJ60817.1 - 0.58 11.1 10.0 1.6 9.7 0.0 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ60817.1 - 0.94 10.3 3.5 23 5.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDJ60817.1 - 2 8.4 6.0 3.1 7.8 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60817.1 - 4.5 7.5 8.5 40 4.6 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 CDJ60820.1 - 4.4e-39 134.6 4.0 4.4e-39 134.6 4.0 3.8 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 CDJ60820.1 - 3e-29 101.9 0.0 2.6e-22 79.0 0.0 3.4 2 1 1 3 3 3 2 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 CDJ60820.1 - 1.5e-21 76.6 2.1 6.8e-14 51.9 0.0 4.1 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 CDJ60820.1 - 2e-08 34.4 0.5 9.4e-08 32.3 0.2 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF4366 PF14283.6 CDJ60820.1 - 0.049 13.7 6.7 6 6.9 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4366) DUF4199 PF13858.6 CDJ60820.1 - 0.057 13.8 5.3 0.44 10.9 1.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF4064 PF13273.6 CDJ60820.1 - 0.31 11.3 1.7 3.6 7.9 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Zip PF02535.22 CDJ60820.1 - 2.5 7.3 12.3 0.25 10.5 0.1 3.8 3 0 0 3 3 3 0 ZIP Zinc transporter MCM PF00493.23 CDJ60821.1 - 1.9e-84 282.3 0.0 3.1e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDJ60821.1 - 4.4e-14 52.4 0.1 1.5e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CDJ60821.1 - 1.8e-05 24.3 0.1 0.0094 15.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDJ60821.1 - 9.6e-05 22.3 0.1 0.0015 18.4 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDJ60821.1 - 0.0053 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SF1-HH PF16275.5 CDJ60821.1 - 0.055 13.8 0.7 0.13 12.7 0.7 1.6 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain AAA PF00004.29 CDJ60821.1 - 0.055 13.9 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Kelch_3 PF13415.6 CDJ60822.1 - 3e-16 59.2 8.8 4.5e-09 36.4 0.2 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ60822.1 - 2.2e-13 49.9 5.2 1.5e-05 24.8 0.8 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CDJ60822.1 - 9.4e-13 48.0 9.3 9.7e-06 25.5 0.8 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDJ60822.1 - 4.6e-08 33.1 10.4 8.7e-06 25.8 0.6 3.3 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CDJ60822.1 - 1.4e-07 31.2 15.6 0.00058 19.7 0.6 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CDJ60822.1 - 0.00046 19.7 15.3 0.002 17.7 0.1 4.4 4 1 0 4 4 4 2 Kelch motif Prefoldin_2 PF01920.20 CDJ60822.1 - 0.00069 19.5 0.6 0.0012 18.7 0.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF4795 PF16043.5 CDJ60822.1 - 0.0019 17.8 0.7 0.0026 17.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF4678 PF15727.5 CDJ60822.1 - 0.0076 15.6 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4678) DUF241 PF03087.14 CDJ60822.1 - 0.0085 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Yuri_gagarin PF15934.5 CDJ60822.1 - 0.012 15.5 0.8 0.016 15.0 0.8 1.1 1 0 0 1 1 1 0 Yuri gagarin APG6_N PF17675.1 CDJ60822.1 - 0.09 13.3 1.1 0.12 12.9 1.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 CDJ60822.1 - 0.13 12.4 2.4 0.45 10.6 0.7 2.4 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 HAUS6_N PF14661.6 CDJ60822.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Gon7 PF08738.10 CDJ60822.1 - 0.26 11.4 1.3 0.94 9.6 1.2 1.9 1 1 1 2 2 2 0 Gon7 family TFIIS_C PF01096.18 CDJ60823.1 - 1.7e-14 53.3 3.6 1.7e-14 53.3 3.6 3.4 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 CDJ60823.1 - 0.0072 16.4 11.5 0.63 10.2 0.0 4.6 3 1 0 3 3 3 1 Zinc ribbon domain zf-FPG_IleRS PF06827.14 CDJ60823.1 - 0.053 13.4 7.2 0.85 9.5 0.6 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DNA_RNApol_7kD PF03604.13 CDJ60823.1 - 0.086 12.5 0.2 0.086 12.5 0.2 4.2 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 CDJ60823.1 - 0.64 10.0 11.2 0.72 9.8 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 CDJ60823.1 - 3.5 7.7 10.8 1.5 8.9 0.7 3.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2757 PF10955.8 CDJ60823.1 - 4.6 7.6 8.6 39 4.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Exo_endo_phos PF03372.23 CDJ60824.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FliJ PF02050.16 CDJ60825.1 - 0.011 16.0 2.9 0.014 15.6 2.9 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein ABC_ATPase PF09818.9 CDJ60826.1 - 1.3e-149 498.8 0.0 1.9e-149 498.3 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CDJ60826.1 - 0.00033 21.2 0.0 0.00045 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDJ60826.1 - 0.049 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SUIM_assoc PF16619.5 CDJ60828.1 - 2.9 8.0 7.9 13 5.9 5.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Trehalose_PPase PF02358.16 CDJ60829.1 - 0.065 12.4 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase DUF3584 PF12128.8 CDJ60830.1 - 0.37 8.3 18.9 0.41 8.1 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Paramyxo_ncap PF00973.19 CDJ60830.1 - 1.1 8.1 6.9 1.2 7.9 6.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3807 PF12720.7 CDJ60830.1 - 6 7.1 19.2 14 5.9 19.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) XRN_M PF17846.1 CDJ60830.1 - 7.8 5.3 11.1 9.5 5.0 11.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain LMBR1 PF04791.16 CDJ60830.1 - 9.8 4.9 8.5 12 4.7 8.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Glu_dehyd_C PF16912.5 CDJ60831.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus BUD22 PF09073.10 CDJ60834.1 - 1.9 7.7 35.4 0.22 10.9 12.2 2.5 2 0 0 2 2 2 0 BUD22 Hydrolase PF00702.26 CDJ60836.1 - 2.1e-15 57.6 0.0 3.5e-11 43.8 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDJ60836.1 - 0.0039 17.0 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ArfGap PF01412.18 CDJ60837.1 - 6.6e-13 48.8 0.4 4.4e-08 33.2 0.0 2.7 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf Lipoprotein_2 PF00921.17 CDJ60837.1 - 0.042 13.4 7.2 0.068 12.7 7.2 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein CYSTM PF12734.7 CDJ60837.1 - 1.6 9.1 6.3 16 5.9 1.3 2.7 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance SARAF PF06682.12 CDJ60838.1 - 0.0041 16.8 0.6 0.0041 16.8 0.6 2.3 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis ATP11 PF06644.11 CDJ60838.1 - 0.026 14.3 6.6 0.65 9.7 1.5 2.2 2 0 0 2 2 2 0 ATP11 protein NAM-associated PF14303.6 CDJ60838.1 - 0.24 12.1 11.7 0.16 12.6 0.8 2.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Hydrolase_3 PF08282.12 CDJ60840.1 - 0.0022 17.8 0.3 0.0022 17.8 0.3 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase CytochromB561_N PF09786.9 CDJ60840.1 - 0.037 13.0 3.1 0.042 12.9 3.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.13 CDJ60840.1 - 0.046 13.7 18.6 0.048 13.7 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 CDJ60840.1 - 0.17 10.5 17.9 0.19 10.4 17.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 CDJ60840.1 - 0.25 10.9 19.1 0.27 10.8 19.1 1.1 1 0 0 1 1 1 0 Spt20 family Chon_Sulph_att PF06566.11 CDJ60840.1 - 0.25 11.2 4.1 0.3 10.9 4.1 1.0 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain BAT2_N PF07001.11 CDJ60840.1 - 0.27 11.7 9.1 0.34 11.3 9.1 1.2 1 0 0 1 1 1 0 BAT2 N-terminus ALMT PF11744.8 CDJ60840.1 - 0.27 10.0 2.5 0.29 9.9 2.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 CDJ60840.1 - 0.31 9.9 12.6 0.33 9.8 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CDJ60840.1 - 0.32 11.6 12.0 0.43 11.2 12.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Adeno_PV PF03910.13 CDJ60840.1 - 0.86 8.2 5.5 0.9 8.2 5.5 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV BRF1 PF07741.13 CDJ60840.1 - 1.2 9.5 6.8 1.7 9.1 6.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Hydrolase PF00702.26 CDJ60840.1 - 1.9 8.7 8.6 0.53 10.5 5.3 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Activator_LAG-3 PF11498.8 CDJ60840.1 - 2.9 6.8 25.5 3.5 6.5 25.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4834 PF16118.5 CDJ60840.1 - 4 8.5 5.7 5.3 8.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 CDJ60840.1 - 4.3 6.0 5.5 4.5 5.9 5.5 1.1 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 CDJ60840.1 - 4.8 6.2 11.5 5.7 5.9 11.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 CDJ60840.1 - 4.9 7.1 5.4 5.7 6.9 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Utp14 PF04615.13 CDJ60841.1 - 0.035 12.7 22.1 0.063 11.8 22.1 1.4 1 0 0 1 1 1 0 Utp14 protein Bud13 PF09736.9 CDJ60841.1 - 0.19 12.1 13.5 0.23 11.9 4.0 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF4770 PF15994.5 CDJ60841.1 - 0.51 10.6 15.0 1.1 9.5 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MAT1 PF06391.13 CDJ60841.1 - 2.2 8.0 19.9 0.95 9.3 5.8 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CDC37_N PF03234.14 CDJ60841.1 - 2.9 8.8 15.6 0.81 10.6 4.4 2.5 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Peptidase_S49_N PF08496.10 CDJ60841.1 - 3.8 7.5 11.4 7.1 6.7 0.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spore_III_AF PF09581.10 CDJ60841.1 - 6.4 6.8 11.0 0.99 9.4 5.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) TPR_1 PF00515.28 CDJ60844.1 - 1.1e-09 37.6 0.1 8.6e-07 28.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 CDJ60844.1 - 9e-08 33.0 0.0 2.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_2 PF07719.17 CDJ60844.1 - 2.7e-07 30.2 0.4 0.003 17.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ60844.1 - 2e-06 27.6 0.0 0.0017 18.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ60844.1 - 0.00017 21.8 0.1 1.2 9.5 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ60844.1 - 0.00029 20.7 0.1 0.64 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ60844.1 - 0.0005 20.5 0.0 0.0014 19.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ60844.1 - 0.0013 19.4 0.1 5 8.2 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ60844.1 - 0.006 16.3 0.0 1.3 8.8 0.0 2.7 1 1 1 2 2 2 1 TPR repeat Methyltransf_24 PF13578.6 CDJ60844.1 - 0.11 13.5 0.3 5.7 8.0 0.0 3.3 3 1 0 3 3 3 0 Methyltransferase domain CIAPIN1 PF05093.13 CDJ60845.1 - 2.7 8.5 9.2 0.07 13.6 1.8 2.2 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SelP_N PF04592.14 CDJ60846.1 - 0.013 14.9 8.4 0.036 13.5 8.4 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex24p PF06398.11 CDJ60846.1 - 0.063 12.3 0.2 0.2 10.6 0.1 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin BBS2_N PF14781.6 CDJ60846.1 - 0.067 13.1 1.3 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Spc24 PF08286.11 CDJ60846.1 - 2.8 8.2 6.7 4.5 7.6 1.6 3.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Secretin_N_2 PF07655.13 CDJ60846.1 - 3.3 8.3 17.1 1.2 9.7 3.1 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Spt20 PF12090.8 CDJ60846.1 - 7.2 6.1 22.4 5.2 6.6 10.8 2.9 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 CDJ60846.1 - 9.9 5.7 35.7 0.028 14.0 4.6 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SKIP_SNW PF02731.15 CDJ60847.1 - 2.5e-69 232.0 1.7 2.5e-69 232.0 1.7 2.7 3 0 0 3 3 3 1 SKIP/SNW domain Kelch_3 PF13415.6 CDJ60848.1 - 0.0013 19.0 1.0 1.7 9.0 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CDJ60848.1 - 0.0029 17.6 0.1 0.0085 16.1 0.1 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain RskA PF10099.9 CDJ60848.1 - 0.0032 17.8 11.2 0.0032 17.8 11.2 24.7 10 6 8 18 18 18 1 Anti-sigma-K factor rskA Kelch_5 PF13854.6 CDJ60848.1 - 0.016 15.1 0.0 0.11 12.5 0.0 2.5 1 0 0 1 1 1 0 Kelch motif TraT PF05818.12 CDJ60849.1 - 0.0031 17.2 3.0 0.0031 17.2 3.0 5.1 2 2 2 4 4 4 1 Enterobacterial TraT complement resistance protein RskA PF10099.9 CDJ60849.1 - 0.0078 16.5 9.2 0.0078 16.5 9.2 6.1 2 1 2 4 4 4 2 Anti-sigma-K factor rskA Utp14 PF04615.13 CDJ60849.1 - 0.073 11.6 30.8 0.0091 14.6 23.6 2.1 2 0 0 2 2 2 0 Utp14 protein O-antigen_lig PF13425.6 CDJ60849.1 - 0.44 9.3 7.3 0.78 8.5 7.3 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Blt1 PF12754.7 CDJ60849.1 - 3.3 8.0 7.5 0.71 10.2 1.9 2.8 1 1 0 2 2 2 0 Blt1 N-terminal domain Band_3_cyto PF07565.13 CDJ60849.1 - 3.5 7.4 32.5 0.1 12.4 16.5 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF3439 PF11921.8 CDJ60849.1 - 6.6 6.7 9.1 0.1 12.6 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) TMEM132D_C PF15706.5 CDJ60850.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LepA_C PF06421.12 CDJ60851.1 - 9.6e-41 138.3 0.0 1.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CDJ60851.1 - 4.4e-09 36.3 0.0 2e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CDJ60851.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CDJ60851.1 - 0.0079 16.3 0.0 0.03 14.4 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II Phage_HK97_TLTM PF06120.11 CDJ60851.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Sec63 PF02889.16 CDJ60853.1 - 7.6e-145 480.8 0.0 2.2e-84 282.7 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDJ60853.1 - 1.1e-42 145.8 1.3 8.5e-25 87.5 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDJ60853.1 - 5e-32 110.4 0.5 1.5e-31 108.9 0.5 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CDJ60853.1 - 1.4e-18 67.5 0.0 2.6e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDJ60853.1 - 2.7e-13 50.2 0.0 2.2e-07 31.2 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ60853.1 - 0.0011 19.3 0.4 0.16 12.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ60853.1 - 0.13 12.6 0.0 0.65 10.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Penicil_amidase PF01804.18 CDJ60854.1 - 3.8e-106 356.7 0.1 7.7e-94 316.0 0.1 2.3 2 1 0 2 2 2 2 Penicillin amidase zf-U1 PF06220.12 CDJ60855.1 - 0.0026 17.5 0.6 0.0026 17.5 0.6 2.1 2 0 0 2 2 2 1 U1 zinc finger WW PF00397.26 CDJ60855.1 - 0.05 13.7 0.8 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 WW domain Ribosomal_S2 PF00318.20 CDJ60855.1 - 8.5 5.5 8.8 0.16 11.2 1.4 1.8 2 0 0 2 2 2 0 Ribosomal protein S2 Peptidase_M24 PF00557.24 CDJ60856.1 - 1.4e-37 129.4 0.0 2.2e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CDJ60856.1 - 1.2e-34 119.7 0.0 1.6e-33 116.1 0.0 2.5 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CDJ60856.1 - 5.6e-24 84.0 1.3 2.1e-23 82.2 0.0 2.7 4 0 0 4 4 4 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDJ60856.1 - 1.3e-18 68.0 0.0 6.2e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain cEGF PF12662.7 CDJ60857.1 - 2.4e-05 24.1 36.9 0.019 14.9 0.3 7.5 7 1 0 7 7 7 4 Complement Clr-like EGF-like EGF PF00008.27 CDJ60857.1 - 0.025 14.9 40.6 0.86 10.0 0.1 9.4 9 1 0 9 9 9 0 EGF-like domain EGF_3 PF12947.7 CDJ60857.1 - 0.36 11.0 0.1 0.36 11.0 0.1 8.0 8 0 0 8 8 8 0 EGF domain RANK_CRD_2 PF18278.1 CDJ60857.1 - 7.2 6.9 30.6 0.84 9.8 0.5 7.5 7 1 1 8 8 8 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 ASH PF15780.5 CDJ60858.1 - 0.059 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ASH PF15780.5 CDJ60859.1 - 5.3e-13 49.0 0.1 0.0018 18.4 0.0 3.4 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CDJ60859.1 - 1.3e-05 25.0 0.0 0.11 12.4 0.0 3.5 3 1 0 3 3 3 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CDJ60859.1 - 0.0012 18.8 0.7 0.78 9.8 0.0 4.3 3 2 1 4 4 4 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 CDJ60859.1 - 0.004 16.2 0.0 0.39 9.6 0.0 2.5 2 1 1 3 3 3 2 MYCBP-associated protein family TMEM131_like PF12371.8 CDJ60859.1 - 0.0066 16.7 0.2 0.94 9.8 0.0 3.0 3 0 0 3 3 3 1 Transmembrane protein 131-like DUF1573 PF07610.11 CDJ60860.1 - 9.9e-05 22.3 0.0 0.32 11.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1573) DDOST_48kD PF03345.14 CDJ60862.1 - 1.2e-09 37.6 0.2 0.00032 19.7 0.0 2.5 1 1 2 3 3 3 2 Oligosaccharyltransferase 48 kDa subunit beta Pox_A_type_inc PF04508.12 CDJ60863.1 - 3.8 7.5 6.6 2 8.4 0.3 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.11 CDJ60863.1 - 5.1 7.6 12.1 5.6 7.4 0.1 4.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Heme_oxygenase PF01126.20 CDJ60864.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Heme oxygenase CAP PF00188.26 CDJ60865.1 - 5.7e-05 24.0 0.2 7.8e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cofilin_ADF PF00241.20 CDJ60866.1 - 9.7e-27 93.2 0.0 1.2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rtf2 PF04641.12 CDJ60868.1 - 5.9e-45 153.7 0.6 1.2e-44 152.6 0.6 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger Nha1_C PF08619.10 CDJ60868.1 - 0.062 12.5 5.6 0.086 12.0 5.6 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Aconitase PF00330.20 CDJ60869.1 - 3.7e-170 566.9 0.0 5.2e-170 566.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDJ60869.1 - 1.6e-41 141.7 0.0 2.6e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CytB6-F_Fe-S PF08802.10 CDJ60870.1 - 0.52 10.4 3.8 1.2 9.2 0.7 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit EF-hand_1 PF00036.32 CDJ60871.1 - 9.5e-27 90.5 13.6 4.2e-05 22.8 0.3 6.6 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 CDJ60871.1 - 3.2e-25 88.4 11.3 1.9e-09 37.9 0.8 3.9 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ60871.1 - 1.8e-21 74.2 10.0 0.00035 20.3 0.3 6.7 5 1 1 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 CDJ60871.1 - 2.8e-21 74.0 13.2 9.3e-05 21.8 0.3 6.5 6 0 0 6 6 6 5 EF hand SPARC_Ca_bdg PF10591.9 CDJ60871.1 - 1.2e-09 38.5 6.4 0.0072 16.6 0.2 3.3 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDJ60871.1 - 1.1e-06 28.4 14.6 0.03 14.2 0.1 5.6 4 2 2 6 6 6 2 EF-hand domain pair Arg_decarbox_C PF17944.1 CDJ60871.1 - 0.016 15.8 0.7 4.7 7.8 0.0 3.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension sCache_2 PF17200.4 CDJ60871.1 - 0.034 14.0 1.9 5.3 6.9 0.0 2.9 2 1 0 2 2 2 0 Single Cache domain 2 Unstab_antitox PF09720.10 CDJ60871.1 - 0.042 13.9 0.1 0.042 13.9 0.1 3.1 5 0 0 5 5 5 0 Putative addiction module component DUF3867 PF12983.7 CDJ60871.1 - 0.087 12.9 2.4 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Dockerin_1 PF00404.18 CDJ60871.1 - 0.093 12.9 2.7 6.6 7.0 0.2 3.7 2 2 2 4 4 4 0 Dockerin type I domain Glutaredoxin PF00462.24 CDJ60871.1 - 0.23 11.7 0.5 5.2 7.4 0.0 3.0 2 1 1 3 3 3 0 Glutaredoxin Bac_globin PF01152.21 CDJ60871.1 - 0.27 11.4 1.7 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial-like globin DUF533 PF04391.12 CDJ60871.1 - 0.42 10.2 5.3 0.45 10.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Iron_permease PF04120.12 CDJ60871.1 - 0.64 9.8 3.7 3.2 7.5 0.3 2.4 2 1 0 2 2 2 0 Low affinity iron permease DUF3349 PF11829.8 CDJ60871.1 - 1.8 9.4 4.7 8.1 7.3 0.2 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3349) Hydrolase PF00702.26 CDJ60872.1 - 2e-14 54.4 1.1 2.6e-06 27.9 0.1 3.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDJ60872.1 - 9.7e-08 31.7 0.0 0.00057 19.5 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Spore_YhcN_YlaJ PF09580.10 CDJ60872.1 - 0.0054 16.8 0.5 0.0054 16.8 0.5 3.6 5 0 0 5 5 5 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ERF PF04404.12 CDJ60872.1 - 0.019 14.8 0.7 0.019 14.8 0.7 4.1 4 0 0 4 4 4 0 ERF superfamily SUIM_assoc PF16619.5 CDJ60872.1 - 1.3 9.1 0.0 0.076 13.1 2.1 10.0 8 2 2 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 ApbA PF02558.16 CDJ60873.1 - 0.0016 18.1 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Phostensin_N PF13916.6 CDJ60873.1 - 0.047 14.0 4.8 0.096 13.0 2.4 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal IATP PF04568.12 CDJ60873.1 - 0.11 12.9 4.2 0.88 10.0 0.9 3.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Nab1 PF04902.12 CDJ60873.1 - 0.22 11.9 10.2 0.065 13.6 6.9 1.8 2 0 0 2 2 2 0 Conserved region in Nab1 SAS-6_N PF16531.5 CDJ60874.1 - 1.1e-12 48.3 0.0 1.1e-12 48.3 0.0 4.4 3 3 1 4 4 4 1 Centriolar protein SAS N-terminal HATPase_c PF02518.26 CDJ60875.1 - 0.0018 18.7 0.0 0.025 15.1 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 CDJ60875.1 - 0.007 16.4 16.7 0.007 16.4 16.7 3.7 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 CDJ60877.1 - 1.7 7.4 17.1 1.9 7.3 17.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Chorion_2 PF03964.15 CDJ60877.1 - 6.9 7.6 14.8 4.5 8.2 4.4 2.1 2 0 0 2 2 2 0 Chorion family 2 Fcf2 PF08698.11 CDJ60878.1 - 1.2e-10 41.6 0.1 1.4e-09 38.2 0.1 2.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing SR-25 PF10500.9 CDJ60879.1 - 0.00095 18.8 16.1 0.00095 18.8 16.1 15.2 11 3 6 18 18 18 4 Nuclear RNA-splicing-associated protein DUF4131 PF13567.6 CDJ60880.1 - 1.2 8.7 5.0 4.1 7.0 4.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) EMC1_C PF07774.13 CDJ60882.1 - 4.9e-25 88.5 0.0 2e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CDJ60882.1 - 0.00023 20.8 13.7 0.0096 15.5 11.6 3.3 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 CDJ60882.1 - 0.0064 16.4 1.0 0.94 9.5 0.1 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat STAC2_u1 PF16664.5 CDJ60882.1 - 2.3 8.7 5.4 8.7 6.8 5.4 2.0 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Peroxin-22 PF12827.7 CDJ60883.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family PEX11 PF05648.14 CDJ60884.1 - 0.0079 15.7 1.3 0.018 14.5 1.3 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sec66 PF09802.9 CDJ60885.1 - 3.9e-08 33.1 4.9 3.9e-08 33.1 4.9 2.1 3 0 0 3 3 3 1 Preprotein translocase subunit Sec66 Ost5 PF05251.12 CDJ60885.1 - 0.069 13.4 0.6 0.14 12.4 0.6 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Suf PF05843.14 CDJ60885.1 - 1.3 8.9 18.8 2.4 8.1 18.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4064 PF13273.6 CDJ60885.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Serinc PF03348.15 CDJ60885.1 - 2.5 6.9 5.6 7.3 5.4 3.9 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-RVT PF13966.6 CDJ60888.1 - 0.00064 20.4 0.1 0.001 19.7 0.1 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase TFIIA PF03153.13 CDJ60889.1 - 0.0021 18.2 5.4 0.0027 17.8 5.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ60889.1 - 0.0023 17.0 5.9 0.0023 17.0 5.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4407 PF14362.6 CDJ60889.1 - 0.033 13.5 1.6 0.05 12.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gti1_Pac2 PF09729.9 CDJ60889.1 - 0.11 12.5 0.5 0.17 12.0 0.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 CDJ60889.1 - 0.19 10.4 0.8 0.25 10.1 0.8 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CDJ60889.1 - 0.55 10.2 5.1 0.98 9.3 5.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CDJ60889.1 - 3.1 8.8 6.0 0.34 11.9 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Methyltransf_16 PF10294.9 CDJ60890.1 - 5.3e-09 36.1 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CDJ60890.1 - 0.00024 20.7 0.1 0.00049 19.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDJ60890.1 - 0.00031 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ60890.1 - 0.0011 19.6 0.0 0.028 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDJ60890.1 - 0.0012 18.3 0.1 0.003 17.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDJ60890.1 - 0.022 14.7 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CDJ60890.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 CDJ60890.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 CDJ60890.1 - 0.19 11.5 0.0 4.4 7.1 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain Cyclin PF08613.11 CDJ60891.1 - 4e-29 102.1 0.5 7.8e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CDJ60891.1 - 2.5e-11 43.4 0.1 4e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NAD_Gly3P_dh_N PF01210.23 CDJ60892.1 - 3.2e-41 140.9 0.0 5.5e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CDJ60892.1 - 1.7e-38 132.1 0.1 2.6e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SseB PF07179.12 CDJ60892.1 - 0.052 13.8 0.1 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 SseB protein N-terminal domain PreAtp-grasp PF18604.1 CDJ60892.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain PfkB PF00294.24 CDJ60894.1 - 7.2e-40 137.2 1.3 1.7e-33 116.2 0.5 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Importin_rep_6 PF18829.1 CDJ60895.1 - 0.00037 20.6 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 Importin repeat 6 Tymo_coat PF00983.18 CDJ60897.1 - 0.013 15.3 0.1 0.03 14.2 0.1 1.6 1 1 0 1 1 1 0 Tymovirus coat protein DUF2205 PF10224.9 CDJ60898.1 - 0.0084 16.1 1.2 0.0084 16.1 1.2 2.8 3 0 0 3 3 3 1 Short coiled-coil protein DUF2486 PF10667.9 CDJ60899.1 - 0.0007 19.9 4.7 0.00086 19.6 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) Metallophos PF00149.28 CDJ60899.1 - 0.023 15.2 0.1 0.03 14.8 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Med3 PF11593.8 CDJ60899.1 - 0.023 13.9 10.4 0.029 13.6 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mobilization_B PF17511.2 CDJ60899.1 - 0.075 13.4 5.7 0.099 13.0 5.7 1.1 1 0 0 1 1 1 0 Mobilization protein B CDK2AP PF09806.9 CDJ60899.1 - 0.15 12.1 11.2 0.21 11.6 11.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MID_MedPIWI PF18296.1 CDJ60899.1 - 0.23 11.2 5.2 0.35 10.6 5.2 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Spt20 PF12090.8 CDJ60899.1 - 0.95 9.0 13.5 1.4 8.5 13.5 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CDJ60899.1 - 7.4 5.2 7.4 9.8 4.8 7.4 1.1 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 CDJ60899.1 - 7.6 6.3 6.3 11 5.8 6.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus Pkinase PF00069.25 CDJ60900.1 - 1.3e-49 168.9 0.0 2e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60900.1 - 6.9e-23 81.3 0.0 1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ60900.1 - 9.6e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDJ60900.1 - 0.0023 17.3 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDJ60900.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDJ60900.1 - 0.019 13.9 0.1 0.019 13.9 0.1 1.8 2 1 0 2 2 2 0 Haspin like kinase domain YukC PF10140.9 CDJ60900.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC AdenylateSensor PF16579.5 CDJ60900.1 - 0.22 12.0 0.2 29 5.2 0.1 3.2 1 1 1 2 2 2 0 Adenylate sensor of SNF1-like protein kinase Porphobil_deam PF01379.20 CDJ60901.1 - 2e-44 151.6 10.8 6.4e-40 136.8 7.5 3.9 2 1 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CDJ60901.1 - 6e-14 52.2 0.2 1.7e-13 50.7 0.2 1.9 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF349 PF03993.12 CDJ60901.1 - 0.76 10.1 10.4 0.046 14.0 2.7 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Glyco_transf_5 PF08323.11 CDJ60902.1 - 4.1e-33 115.1 1.3 5.2e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 CDJ60902.1 - 1.7e-16 60.2 0.0 4.8e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 CDJ60902.1 - 5.4e-12 45.6 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDJ60902.1 - 1.7e-06 28.5 0.0 4.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hyccin PF09790.9 CDJ60903.1 - 0.0015 17.7 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Hyccin WRNPLPNID PF15017.6 CDJ60903.1 - 4.5 8.2 8.2 29 5.7 3.6 3.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box IMCp PF12314.8 CDJ60904.1 - 1.6e-08 34.7 55.9 3.7e-08 33.5 28.3 3.4 2 1 1 3 3 3 2 Inner membrane complex protein Thioredoxin PF00085.20 CDJ60905.1 - 1.2e-27 95.9 0.0 1.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDJ60905.1 - 0.00033 21.1 0.2 0.0047 17.4 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 CDJ60905.1 - 0.00052 20.0 0.0 0.00079 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CDJ60905.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CDJ60905.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 CDJ60905.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 CDJ60905.1 - 0.02 15.2 0.0 0.34 11.3 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Pollen_allerg_2 PF01620.16 CDJ60905.1 - 0.036 14.3 0.5 0.052 13.8 0.5 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) OST3_OST6 PF04756.13 CDJ60905.1 - 0.04 13.3 0.1 0.073 12.4 0.0 1.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family HyaE PF07449.11 CDJ60905.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE JAB PF01398.21 CDJ60906.1 - 6.9e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDJ60906.1 - 7.5e-10 39.2 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function HTH_3 PF01381.22 CDJ60906.1 - 0.037 14.1 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix ApoLp-III PF07464.11 CDJ60907.1 - 5.8 7.0 9.7 13 5.9 0.0 4.3 6 0 0 6 6 6 0 Apolipophorin-III precursor (apoLp-III) EamA PF00892.20 CDJ60908.1 - 5.6e-10 39.5 16.6 5.6e-10 39.5 16.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family SlyX PF04102.12 CDJ60909.1 - 2.8 8.6 15.4 7.7 7.2 15.4 1.7 1 0 0 1 1 1 0 SlyX SRP14 PF02290.15 CDJ60910.1 - 1.1e-16 60.9 5.4 1.2e-16 60.8 0.0 2.7 2 1 0 2 2 2 1 Signal recognition particle 14kD protein TFIIA PF03153.13 CDJ60910.1 - 0.14 12.2 20.6 0.14 12.1 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 CDJ60911.1 - 5.4e-46 157.2 0.0 1.2e-45 156.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDJ60911.1 - 3.1e-12 46.6 0.0 6.8e-11 42.3 0.0 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CDJ60911.1 - 5.5e-11 42.1 8.9 7.5e-06 25.7 0.1 3.5 4 0 0 4 4 4 2 UBA/TS-N domain UCH_1 PF13423.6 CDJ60911.1 - 2.6e-09 37.1 0.0 0.00024 20.8 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RuvA_C PF07499.13 CDJ60911.1 - 0.00037 20.9 2.5 0.021 15.3 0.1 3.5 3 0 0 3 3 3 1 RuvA, C-terminal domain Dis3l2_C_term PF17877.1 CDJ60911.1 - 0.057 13.7 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal SOG2 PF10428.9 CDJ60912.1 - 6.6 5.8 16.3 7.9 5.5 16.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4054 PF13262.6 CDJ60912.1 - 8.9 6.4 10.6 2.3 8.3 0.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4054) Sporozoite_P67 PF05642.11 CDJ60913.1 - 0.43 8.6 1.6 1.1 7.2 1.6 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RdRP_4 PF02123.16 CDJ60914.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase zf-CCCH_4 PF18044.1 CDJ60915.1 - 0.0029 17.4 0.2 0.0051 16.6 0.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CDJ60915.1 - 0.0048 17.6 2.2 0.0079 16.9 0.0 2.0 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 CDJ60915.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDJ60915.1 - 0.054 13.6 0.2 0.095 12.8 0.2 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CDJ60915.1 - 0.11 13.0 0.5 0.2 12.2 0.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDJ60915.1 - 0.16 12.2 0.5 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger containing family Peptidase_S15 PF02129.18 CDJ60915.1 - 0.89 9.1 5.0 1.1 8.8 4.2 1.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) SUIM_assoc PF16619.5 CDJ60916.1 - 0.89 9.7 6.0 0.23 11.5 1.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UQ_con PF00179.26 CDJ60917.1 - 2e-39 134.4 0.1 2.9e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ60917.1 - 0.047 13.4 0.1 0.079 12.7 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B DUF3273 PF11677.8 CDJ60918.1 - 8.3e-94 313.8 3.7 9.8e-94 313.6 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2569 PF10754.9 CDJ60918.1 - 0.02 15.4 3.4 0.037 14.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Tetraspanin PF00335.20 CDJ60918.1 - 6.1 6.5 7.3 18 4.9 2.7 2.8 1 1 1 3 3 3 0 Tetraspanin family HAD PF12710.7 CDJ60919.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ntox15 PF15604.6 CDJ60919.1 - 0.28 11.3 2.2 0.53 10.4 2.2 1.3 1 0 0 1 1 1 0 Novel toxin 15 GPI2 PF06432.11 CDJ60920.1 - 4e-73 246.3 13.9 5.1e-73 245.9 13.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Ac76 PF05814.11 CDJ60920.1 - 3.3 7.8 7.9 0.58 10.2 0.1 3.2 4 0 0 4 4 4 0 Orf76 (Ac76) UPF0016 PF01169.19 CDJ60921.1 - 3.3e-26 91.4 26.3 6.9e-16 58.4 7.1 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF2076 PF09849.9 CDJ60921.1 - 3.5 7.6 17.1 0.12 12.3 0.6 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Bud13 PF09736.9 CDJ60922.1 - 4.6e-07 30.3 2.7 4.6e-07 30.3 2.7 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.29 CDJ60923.1 - 2.1e-38 131.7 0.0 4.4e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ60923.1 - 6.1e-08 32.3 0.2 1.3e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ60923.1 - 8.1e-05 22.6 0.1 0.00033 20.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ60923.1 - 0.00018 21.9 9.9 0.027 14.8 9.4 3.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDJ60923.1 - 0.00037 20.8 0.2 0.07 13.4 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDJ60923.1 - 0.0022 18.2 0.0 0.0063 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDJ60923.1 - 0.01 16.4 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CDJ60923.1 - 0.02 14.4 0.2 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 CDJ60923.1 - 0.026 14.0 0.0 0.062 12.8 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 CDJ60923.1 - 0.038 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CDJ60923.1 - 0.046 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDJ60923.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDJ60923.1 - 0.058 13.1 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 CDJ60923.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDJ60923.1 - 0.073 13.0 0.4 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CDJ60923.1 - 0.082 12.6 0.2 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ60923.1 - 0.13 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CDJ60923.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 CDJ60923.1 - 0.17 11.6 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 CDJ60923.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 CDJ60923.1 - 0.18 11.0 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 CDJ60923.1 - 0.22 11.5 0.1 0.4 10.7 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PBP_sp32 PF07222.12 CDJ60924.1 - 0.22 11.0 2.4 0.38 10.2 2.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RRM_1 PF00076.22 CDJ60925.1 - 1.8e-36 123.8 0.1 5.1e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDJ60925.1 - 6.5e-06 26.1 0.0 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDJ60925.1 - 1.8e-05 24.5 0.0 0.0055 16.5 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CDJ60925.1 - 0.0069 16.5 0.0 0.68 10.1 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif FixQ PF05545.11 CDJ60926.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF418 PF04235.12 CDJ60926.1 - 0.086 12.8 0.2 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF418) MtaB PF12176.8 CDJ60926.1 - 0.18 10.6 2.3 0.23 10.2 2.3 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit AMP-binding PF00501.28 CDJ60927.1 - 8.8e-16 57.5 0.0 5.7e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Vmethyltransf_C PF08456.10 CDJ60927.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Exonuc_VII_L PF02601.15 CDJ60928.1 - 0.04 13.5 25.4 0.25 10.9 21.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF347 PF03988.12 CDJ60928.1 - 0.21 11.8 6.5 6.7 7.0 4.2 3.2 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) MerC PF03203.14 CDJ60928.1 - 1.1 9.8 9.0 0.31 11.5 0.2 3.0 3 0 0 3 3 3 0 MerC mercury resistance protein CD20 PF04103.15 CDJ60928.1 - 1.7 8.7 7.4 0.21 11.7 1.4 2.4 2 1 1 3 3 3 0 CD20-like family RskA PF10099.9 CDJ60929.1 - 0.019 15.3 20.6 0.026 14.8 20.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Amidase_3 PF01520.18 CDJ60929.1 - 0.21 11.7 6.5 0.23 11.6 6.5 1.1 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase EMC3_TMCO1 PF01956.16 CDJ60929.1 - 0.35 10.6 14.3 0.4 10.4 14.3 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Activator_LAG-3 PF11498.8 CDJ60929.1 - 0.35 9.8 33.6 0.39 9.6 33.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DASH_Spc34 PF08657.10 CDJ60929.1 - 0.37 10.6 14.3 0.39 10.5 14.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 OmpH PF03938.14 CDJ60929.1 - 1.1 9.6 30.2 1.3 9.3 30.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EIF4E-T PF10477.9 CDJ60929.1 - 1.2 7.9 21.8 1.2 7.9 21.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Cyclin_C PF02984.19 CDJ60929.1 - 1.3 9.1 12.6 1.7 8.8 12.6 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Peptidase_S49_N PF08496.10 CDJ60929.1 - 1.5 8.9 10.9 1.6 8.8 10.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NEMP PF10225.9 CDJ60929.1 - 2.7 7.6 8.1 2.8 7.5 8.1 1.0 1 0 0 1 1 1 0 NEMP family ADP_ribosyl_GH PF03747.14 CDJ60929.1 - 3 7.5 9.2 3.1 7.4 9.2 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase FAM199X PF15814.5 CDJ60929.1 - 3.3 6.7 15.4 3.8 6.5 15.4 1.0 1 0 0 1 1 1 0 Protein family FAM199X Peptidase_S15 PF02129.18 CDJ60929.1 - 4.5 6.8 14.5 5 6.6 14.5 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2232 PF09991.9 CDJ60929.1 - 5.5 6.1 8.9 5.9 6.0 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MCU PF04678.13 CDJ60929.1 - 6.6 6.8 12.1 8 6.5 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF945 PF06097.11 CDJ60929.1 - 6.8 5.7 23.6 8 5.4 23.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) TFIIA PF03153.13 CDJ60930.1 - 8.8e-06 26.0 26.3 2.1e-05 24.7 26.3 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CDJ60930.1 - 0.23 11.1 19.5 5.8 6.6 7.9 3.8 4 0 0 4 4 4 0 FAM176 family Med15 PF09606.10 CDJ60930.1 - 7.3 5.1 21.7 10 4.6 21.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YqgB PF11036.8 CDJ60932.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Virulence promoting factor IL34 PF15036.6 CDJ60933.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 MT-A70 PF05063.14 CDJ60934.1 - 8.7e-58 195.0 0.4 1.7e-57 194.1 0.4 1.5 1 0 0 1 1 1 1 MT-A70 RAP1 PF07218.11 CDJ60934.1 - 0.0019 16.6 3.1 0.0019 16.6 3.1 2.8 2 1 0 2 2 2 1 Rhoptry-associated protein 1 (RAP-1) TIM PF00121.18 CDJ60935.1 - 6.3e-81 271.3 0.0 9.4e-81 270.7 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase RskA PF10099.9 CDJ60935.1 - 0.0029 17.9 5.2 0.0053 17.1 5.2 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4763 PF15960.5 CDJ60935.1 - 0.012 15.0 7.7 0.018 14.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF2722 PF10846.8 CDJ60935.1 - 0.027 13.4 1.3 0.034 13.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ60935.1 - 0.036 14.1 10.8 0.064 13.2 10.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.14 CDJ60935.1 - 0.085 13.2 11.0 0.21 11.9 11.0 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1800 PF08811.11 CDJ60935.1 - 0.74 8.8 6.2 0.4 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) Spt20 PF12090.8 CDJ60935.1 - 1 8.9 12.1 1.6 8.3 12.1 1.4 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.8 CDJ60936.1 - 0.0017 17.4 2.3 0.0017 17.4 2.3 5.4 3 1 2 5 5 5 1 Transcriptional activator LAG-3 Telomere_Sde2_2 PF13297.6 CDJ60936.1 - 0.045 13.4 0.5 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Telomere stability C-terminal Ribonuc_red_lgC PF02867.15 CDJ60936.1 - 0.053 12.1 0.1 0.082 11.4 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Phage_TAC_7 PF10109.9 CDJ60936.1 - 0.072 13.2 1.7 0.18 12.0 0.2 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Death_2 PF14786.6 CDJ60936.1 - 9.9 6.1 9.0 0.51 10.3 1.8 2.6 3 0 0 3 3 3 0 Tube Death domain zf-RING_2 PF13639.6 CDJ60937.1 - 3.7e-12 46.4 8.1 3.7e-12 46.4 8.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ60937.1 - 2.4e-09 36.9 6.3 2.4e-09 36.9 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ60937.1 - 3.2e-08 33.2 3.7 3.2e-08 33.2 3.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDJ60937.1 - 8e-08 32.2 1.8 8e-08 32.2 1.8 3.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ60937.1 - 1.4e-07 31.3 6.0 1.4e-07 31.3 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ60937.1 - 1.7e-06 28.2 8.6 1.7e-06 28.2 8.6 3.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDJ60937.1 - 1.4e-05 24.9 6.6 1.4e-05 24.9 6.6 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDJ60937.1 - 0.0028 17.5 4.7 0.0028 17.5 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDJ60937.1 - 0.0067 16.3 4.1 0.0067 16.3 4.1 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDJ60937.1 - 0.48 10.6 8.5 0.13 12.4 4.7 2.1 2 0 0 2 2 1 0 FANCL C-terminal domain RINGv PF12906.7 CDJ60937.1 - 0.52 10.5 6.2 1.5 9.0 6.2 1.9 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CDJ60937.1 - 0.75 9.5 5.8 2.3 7.9 5.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ribbon_3 PF13248.6 CDJ60937.1 - 3.6 7.1 5.3 21 4.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain HTH_28 PF13518.6 CDJ60938.1 - 0.038 14.1 0.1 1.1 9.5 0.0 3.7 2 0 0 2 2 2 0 Helix-turn-helix domain Antimicrobial10 PF08105.11 CDJ60938.1 - 0.56 10.3 3.0 26 5.0 0.8 3.4 2 0 0 2 2 2 0 Metchnikowin family HSP90 PF00183.18 CDJ60939.1 - 6e-110 368.6 5.7 7.6e-110 368.2 5.7 1.0 1 0 0 1 1 1 1 Hsp90 protein GP3_package PF16677.5 CDJ60939.1 - 0.018 15.2 0.1 0.096 12.8 0.0 1.9 1 1 1 2 2 2 0 DNA-packaging protein gp3 Cofac_haem_bdg PF04187.13 CDJ60939.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Methyltransf_16 PF10294.9 CDJ60941.1 - 7.4e-18 64.9 0.0 6.2e-17 61.9 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Ank_4 PF13637.6 CDJ60941.1 - 6.7e-16 58.4 3.4 4.9e-10 39.7 1.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDJ60941.1 - 1e-14 54.8 1.3 3.9e-12 46.6 0.2 2.9 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDJ60941.1 - 3.9e-12 46.0 1.5 8.5e-07 29.2 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CDJ60941.1 - 1e-10 41.6 2.2 5.9e-08 32.8 0.2 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDJ60941.1 - 2.1e-10 39.9 1.0 0.0016 18.7 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_23 PF13489.6 CDJ60941.1 - 6.6e-07 29.3 3.9 1.7e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CDJ60941.1 - 0.0011 18.5 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDJ60941.1 - 0.0027 18.4 0.0 0.0027 18.4 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Spt20 PF12090.8 CDJ60941.1 - 0.011 15.4 36.4 0.1 12.2 2.0 3.4 3 0 0 3 3 3 0 Spt20 family IHABP4_N PF16174.5 CDJ60941.1 - 0.024 15.3 11.3 0.024 15.3 11.3 3.8 4 0 0 4 4 4 0 Intracellular hyaluronan-binding protein 4 N-terminal PrmA PF06325.13 CDJ60941.1 - 0.097 12.0 0.0 0.097 12.0 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3562 PF12085.8 CDJ60941.1 - 0.11 12.1 0.2 0.28 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Zip PF02535.22 CDJ60941.1 - 0.14 11.4 0.4 0.24 10.6 0.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3487 PF11990.8 CDJ60941.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Methyltransf_31 PF13847.6 CDJ60941.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.6 4 0 0 4 4 4 0 Methyltransferase domain DUF1765 PF08578.10 CDJ60942.1 - 4.1e-14 53.1 0.5 7.7e-14 52.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DUF2722 PF10846.8 CDJ60942.1 - 0.00079 18.5 4.2 0.00079 18.5 4.2 8.5 7 2 1 8 8 8 3 Protein of unknown function (DUF2722) Mucin PF01456.17 CDJ60942.1 - 0.0011 19.0 5.9 0.0011 19.0 5.9 7.1 7 0 0 7 7 7 1 Mucin-like glycoprotein F-box-like PF12937.7 CDJ60943.1 - 1.5e-05 24.8 0.2 4.7e-05 23.2 0.2 2.0 1 0 0 1 1 1 1 F-box-like Adaptin_N PF01602.20 CDJ60944.1 - 0.026 13.1 0.4 0.026 13.1 0.4 2.6 3 0 0 3 3 3 0 Adaptin N terminal region SUIM_assoc PF16619.5 CDJ60944.1 - 0.063 13.4 0.0 0.063 13.4 0.0 7.5 5 2 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 DUF2973 PF11189.8 CDJ60944.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2973) Dynein_light PF01221.18 CDJ60944.1 - 8.2 6.8 6.4 0.61 10.4 0.5 2.1 2 0 0 2 2 2 0 Dynein light chain type 1 K_channel_TID PF07941.11 CDJ60945.1 - 0.021 15.3 8.0 0.021 15.3 8.0 1.6 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain YukD PF08817.10 CDJ60945.1 - 0.25 12.1 0.8 0.43 11.3 0.8 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ku_N PF03731.15 CDJ60946.1 - 0.17 11.6 0.1 0.17 11.6 0.1 3.2 3 0 0 3 3 3 0 Ku70/Ku80 N-terminal alpha/beta domain Herpes_UL7 PF01677.16 CDJ60946.1 - 7.1 6.3 6.3 13 5.4 6.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL7 like B56 PF01603.20 CDJ60947.1 - 8.4e-161 535.6 6.5 8.4e-161 535.6 6.5 1.7 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Spt20 PF12090.8 CDJ60947.1 - 0.031 13.9 12.9 0.053 13.1 12.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 CDJ60947.1 - 0.11 11.4 11.8 0.17 10.8 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2052 PF09747.9 CDJ60947.1 - 0.14 12.3 6.8 7.4 6.7 4.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sec7_N PF12783.7 CDJ60947.1 - 0.2 11.6 4.6 0.15 11.9 0.4 2.9 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Peptidase_S49_N PF08496.10 CDJ60947.1 - 0.47 10.5 5.3 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFMR_assoc PF16596.5 CDJ60947.1 - 1.9 8.9 5.7 3.3 8.2 5.7 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR DDHD PF02862.17 CDJ60947.1 - 3.5 7.7 6.3 3.2 7.9 2.8 2.4 3 0 0 3 3 3 0 DDHD domain TAF4 PF05236.14 CDJ60947.1 - 4.7 6.9 17.0 0.11 12.2 9.2 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RPA43_OB PF17875.1 CDJ60947.1 - 5.9 7.5 6.3 37 5.0 2.9 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MAR_sialic_bdg PF10564.9 CDJ60949.1 - 6.6e-74 244.0 18.7 1.3e-26 92.5 1.1 3.3 3 0 0 3 3 3 3 Sialic-acid binding micronemal adhesive repeat DUF1348 PF07080.11 CDJ60949.1 - 0.053 13.4 0.0 10 6.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1348) SUIM_assoc PF16619.5 CDJ60951.1 - 0.0068 16.5 0.0 0.0068 16.5 0.0 16.1 9 3 2 11 11 11 4 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CDJ60952.1 - 0.25 11.3 24.5 1.4 8.9 14.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.28 CDJ60953.1 - 1.3e-11 43.8 0.1 2.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme HGTP_anticodon PF03129.20 CDJ60956.1 - 0.0002 21.5 0.2 0.0006 19.9 0.2 1.8 1 1 0 1 1 1 1 Anticodon binding domain WD40 PF00400.32 CDJ60957.1 - 6.2e-14 52.2 5.7 0.0051 17.6 0.2 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat AAA_6 PF12774.7 CDJ60958.1 - 2.9e-145 483.3 0.0 7.1e-145 482.1 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ60958.1 - 1.6e-106 356.8 5.6 1.6e-106 356.8 5.6 5.5 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDJ60958.1 - 5.7e-102 342.2 6.4 5.7e-102 342.2 6.4 4.0 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CDJ60958.1 - 6e-86 288.0 0.0 1.9e-85 286.3 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDJ60958.1 - 6.4e-70 234.7 17.9 2.3e-64 216.5 0.7 3.8 3 0 0 3 3 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 CDJ60958.1 - 1.7e-67 226.4 0.5 1.7e-61 206.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 CDJ60958.1 - 9.7e-51 172.8 9.9 2.3e-50 171.6 9.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDJ60958.1 - 5.4e-39 133.6 0.0 1.3e-38 132.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CDJ60958.1 - 2.1e-32 112.6 0.0 2.7e-30 105.6 0.0 3.2 1 1 1 2 2 2 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 CDJ60958.1 - 4.8e-22 78.4 0.2 1.5e-05 25.0 0.0 6.3 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDJ60958.1 - 2e-18 66.7 0.0 1.6e-17 63.8 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ60958.1 - 1e-16 61.0 0.0 4.1e-16 59.0 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_heavy PF03028.15 CDJ60958.1 - 5.2e-08 33.0 0.8 8.4e-05 22.6 0.1 3.6 2 1 1 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 CDJ60958.1 - 6.2e-07 30.0 2.8 2.1 8.7 0.0 6.6 6 0 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 CDJ60958.1 - 3.1e-06 27.5 1.1 0.52 10.6 0.0 4.9 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 CDJ60958.1 - 4.1e-05 24.0 0.8 0.3 11.5 0.0 5.0 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ60958.1 - 0.00037 21.1 5.2 0.49 11.0 0.0 5.3 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CDJ60958.1 - 0.0085 15.5 0.1 3.1 7.1 0.0 3.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 CDJ60958.1 - 0.028 14.1 0.1 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 CDJ60958.1 - 0.03 14.0 2.1 3.8 7.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain BAR_3_WASP_bdg PF10456.9 CDJ60958.1 - 0.032 13.7 0.0 2.2 7.7 0.0 3.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein RsgA_GTPase PF03193.16 CDJ60958.1 - 0.097 12.6 0.2 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase SKA2 PF16740.5 CDJ60958.1 - 0.1 12.4 12.3 10 6.0 7.1 4.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 AAA_28 PF13521.6 CDJ60958.1 - 0.1 12.8 3.2 4.5 7.5 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 CDJ60958.1 - 0.24 11.2 0.7 20 5.0 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF3450 PF11932.8 CDJ60958.1 - 3.2 7.0 20.2 0.15 11.3 5.5 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SSP160 PF06933.11 CDJ60959.1 - 0.069 11.4 18.8 0.095 10.9 18.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 CDJ60959.1 - 0.096 12.7 6.3 0.14 12.1 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 CDJ60959.1 - 0.46 10.5 21.5 0.75 9.8 21.5 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 CDJ60959.1 - 0.69 8.0 6.6 0.66 8.0 6.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ran_BP1 PF00638.18 CDJ60961.1 - 4e-38 130.4 3.3 8.1e-38 129.4 3.3 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CDJ60961.1 - 0.056 13.4 3.4 0.22 11.5 3.4 1.9 1 1 0 1 1 1 0 WH1 domain NAD_binding_11 PF14833.6 CDJ60962.1 - 1.1e-32 112.9 0.1 4.9e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 CDJ60962.1 - 1.4e-30 106.6 0.6 3.2e-20 72.9 0.1 2.2 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CDJ60962.1 - 1.7e-05 25.3 0.2 3.3e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CDJ60962.1 - 0.00017 21.7 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CDJ60962.1 - 0.00084 18.7 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDJ60962.1 - 0.0065 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 CDJ60962.1 - 0.016 15.1 0.3 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDJ60962.1 - 0.022 15.0 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 CDJ60962.1 - 0.059 14.2 0.0 0.097 13.5 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2722 PF10846.8 CDJ60963.1 - 4e-05 22.8 0.0 9.5e-05 21.5 0.6 17.2 8 4 8 16 16 16 5 Protein of unknown function (DUF2722) Exonuc_VII_L PF02601.15 CDJ60963.1 - 0.00027 20.6 2.6 0.00027 20.6 2.6 10.6 3 2 4 7 7 7 1 Exonuclease VII, large subunit RskA PF10099.9 CDJ60963.1 - 0.0004 20.7 39.0 0.0012 19.2 4.9 20.8 7 6 7 16 16 16 5 Anti-sigma-K factor rskA zn-ribbon_14 PF16503.5 CDJ60964.1 - 5.6e-07 29.0 5.2 5.6e-07 29.0 5.2 3.9 5 0 0 5 5 5 1 Zinc-ribbon ATP_bind_3 PF01171.20 CDJ60964.1 - 2.1e-05 24.4 2.3 7.5e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 PP-loop family RecR PF02132.15 CDJ60964.1 - 0.0043 16.6 1.5 0.0043 16.6 1.5 2.5 2 0 0 2 2 2 1 RecR protein FAM199X PF15814.5 CDJ60966.1 - 0.0043 16.2 9.0 0.005 15.9 9.0 1.1 1 0 0 1 1 1 1 Protein family FAM199X TFIIA PF03153.13 CDJ60966.1 - 0.1 12.5 14.8 0.11 12.4 14.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 CDJ60966.1 - 0.14 12.7 6.6 0.19 12.3 6.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RskA PF10099.9 CDJ60966.1 - 0.44 10.8 21.6 1.2 9.4 21.6 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 CDJ60966.1 - 0.51 9.3 6.2 0.61 9.1 6.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MSP1_C PF07462.11 CDJ60966.1 - 0.56 8.9 4.6 0.63 8.7 4.6 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dehydrin PF00257.19 CDJ60966.1 - 0.6 10.6 6.9 0.74 10.4 6.9 1.1 1 0 0 1 1 1 0 Dehydrin Hamartin PF04388.12 CDJ60966.1 - 2.1 6.9 6.9 2.2 6.9 6.9 1.0 1 0 0 1 1 1 0 Hamartin protein K_channel_TID PF07941.11 CDJ60966.1 - 3.7 8.1 34.8 0.07 13.6 11.8 2.3 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1645 PF07816.11 CDJ60967.1 - 0.0068 17.0 15.6 0.0068 17.0 15.6 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF1645) GDE_N PF12439.8 CDJ60967.1 - 0.036 13.5 2.6 0.24 10.8 2.0 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Kinesin PF00225.23 CDJ60968.1 - 9.3e-08 31.4 1.2 9.2e-06 24.8 0.2 3.6 3 1 0 4 4 4 2 Kinesin motor domain GYF PF02213.16 CDJ60969.1 - 3.3e-12 45.9 0.0 7.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.25 CDJ60970.1 - 1.6e-05 24.4 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ60970.1 - 2.1e-05 24.0 0.0 7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase MOZ_SAS PF01853.18 CDJ60971.1 - 7.1e-37 126.8 1.6 5.6e-36 123.9 0.7 2.2 1 1 1 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 CDJ60971.1 - 4.3e-20 71.1 0.8 2e-19 68.9 0.4 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ60971.1 - 3.9e-09 36.3 0.2 6.9e-07 29.1 0.1 2.5 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain DUF4590 PF15257.6 CDJ60971.1 - 0.11 12.5 0.9 0.23 11.4 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) RskA PF10099.9 CDJ60971.1 - 0.5 10.6 17.6 0.058 13.7 13.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA THOC2_N PF16134.5 CDJ60972.1 - 0.0053 15.5 0.6 0.0053 15.5 0.6 2.6 2 1 0 2 2 2 1 THO complex subunit 2 N-terminus DNA_topoisoIV PF00521.20 CDJ60973.1 - 5.9e-47 160.5 0.2 5.9e-42 144.1 0.0 2.0 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A ATC_hydrolase PF14196.6 CDJ60973.1 - 0.02 15.7 0.8 2.4 8.9 0.0 2.1 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Spt20 PF12090.8 CDJ60973.1 - 0.087 12.4 8.4 0.1 12.2 3.4 2.1 2 0 0 2 2 2 0 Spt20 family Nup188 PF10487.9 CDJ60973.1 - 0.087 10.7 0.0 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Phage_holin_2_4 PF16082.5 CDJ60973.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like AIG1 PF04548.16 CDJ60973.1 - 0.36 10.1 0.0 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Adaptin_binding PF10199.9 CDJ60974.1 - 0.012 16.2 0.8 0.012 16.2 0.8 11.0 7 4 2 10 10 10 0 Alpha and gamma adaptin binding protein p34 AP2 PF00847.20 CDJ60975.1 - 5.7e-09 36.1 0.2 5.7e-09 36.1 0.2 2.5 2 0 0 2 2 2 1 AP2 domain RskA PF10099.9 CDJ60975.1 - 0.0026 18.1 0.6 0.0026 18.1 0.6 9.5 2 2 5 8 8 8 2 Anti-sigma-K factor rskA DUF812 PF05667.11 CDJ60975.1 - 1.6 7.5 61.5 0.072 12.0 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF812) NAM-associated PF14303.6 CDJ60976.1 - 0.078 13.7 0.0 0.078 13.7 0.0 8.9 3 2 2 6 6 6 0 No apical meristem-associated C-terminal domain Myb_DNA-binding PF00249.31 CDJ60977.1 - 0.0034 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_7 PF13499.6 CDJ60978.1 - 7.6e-19 67.9 0.2 1.1e-11 45.0 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ60978.1 - 4.3e-18 63.4 0.2 7.2e-06 25.2 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDJ60978.1 - 1.1e-16 59.3 1.3 1.8e-06 27.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDJ60978.1 - 2.2e-11 42.7 0.6 3.3e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ60978.1 - 1.8e-10 40.5 2.3 6.4e-05 22.7 0.0 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_11 PF08976.11 CDJ60978.1 - 6.4e-07 30.2 0.1 1.8e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 CDJ60978.1 - 0.00095 19.4 0.0 0.038 14.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDJ60978.1 - 0.022 15.1 0.0 0.077 13.3 0.0 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDJ60978.1 - 0.027 14.6 0.2 0.67 10.2 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain DUF5580 PF17743.1 CDJ60978.1 - 0.029 12.9 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Caleosin PF05042.13 CDJ60978.1 - 0.055 13.4 0.0 0.62 10.0 0.0 2.2 1 1 0 1 1 1 0 Caleosin related protein GPHH PF16905.5 CDJ60978.1 - 0.11 12.3 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated XisH PF08814.10 CDJ60982.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 XisH protein DUF4045 PF13254.6 CDJ60984.1 - 0.5 9.9 26.6 0.69 9.5 26.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 CDJ60984.1 - 0.92 8.9 51.1 1.7 8.0 51.1 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDJ60984.1 - 7.7 4.6 47.8 13 3.9 47.8 1.3 1 0 0 1 1 1 0 Nop14-like family Alpha-amylase PF00128.24 CDJ60986.1 - 1.7 8.1 0.0 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Alpha amylase, catalytic domain START PF01852.19 CDJ60989.1 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 START domain LapA_dom PF06305.11 CDJ60989.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Draxin PF15550.6 CDJ60992.1 - 5.1 6.9 22.9 8.6 6.1 22.9 1.4 1 0 0 1 1 1 0 Draxin Cadherin_C_2 PF16492.5 CDJ60993.1 - 5.8 7.7 0.0 5.8 7.7 0.0 3.7 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal PALP PF00291.25 CDJ60994.1 - 1.1e-47 162.9 2.3 2.8e-47 161.6 2.3 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TruB_C PF09142.11 CDJ60994.1 - 0.19 11.5 0.9 6.7 6.6 0.1 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Pex16 PF08610.10 CDJ60997.1 - 0.0092 15.2 0.7 0.012 14.8 0.7 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1980 PF09323.10 CDJ60997.1 - 1.6 8.6 3.4 1.6 8.6 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) GRP PF07172.11 CDJ60997.1 - 2.1 9.1 6.3 10 6.9 3.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family Dynein_C PF18199.1 CDJ60998.1 - 1.6e-47 162.3 0.0 1.7e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PG_isomerase_N PF18353.1 CDJ60999.1 - 0.025 15.0 0.2 0.025 15.0 0.2 2.5 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain Caldesmon PF02029.15 CDJ60999.1 - 0.56 8.9 21.4 0.99 8.1 21.4 1.3 1 0 0 1 1 1 0 Caldesmon Presenilin PF01080.17 CDJ60999.1 - 9.4 4.9 20.7 19 3.9 20.7 1.5 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 CDJ61000.1 - 0.91 8.6 14.4 1 8.5 14.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_4 PF12799.7 CDJ61001.1 - 9.8e-12 44.9 10.3 2.2e-06 27.9 0.4 3.9 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ61001.1 - 1.8e-09 37.2 8.7 0.0001 22.0 5.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CDJ61001.1 - 0.059 13.5 8.2 2.9 8.2 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 CDJ61001.1 - 0.096 12.2 1.0 1.5 8.3 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeat Adaptin_binding PF10199.9 CDJ61002.1 - 0.036 14.7 2.1 0.083 13.5 0.2 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SPX PF03105.19 CDJ61002.1 - 0.62 9.9 5.4 0.12 12.3 1.3 1.7 2 0 0 2 2 2 0 SPX domain MID_MedPIWI PF18296.1 CDJ61002.1 - 9.2 6.0 9.5 5.5 6.7 4.3 2.2 2 0 0 2 2 2 0 MID domain of medPIWI SR-25 PF10500.9 CDJ61002.1 - 9.4 5.8 12.5 5.3 6.6 10.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_2d PF01409.20 CDJ61003.1 - 1e-31 110.3 0.0 1.9e-12 47.2 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CDJ61003.1 - 9.3e-18 64.4 0.6 5.4e-14 52.4 0.0 2.8 2 0 0 2 2 2 2 Ferredoxin-fold anticodon binding domain SPX PF03105.19 CDJ61003.1 - 0.057 13.3 17.9 0.76 9.6 11.4 3.1 2 1 0 2 2 2 0 SPX domain Peptidase_M16 PF00675.20 CDJ61004.1 - 8e-22 77.8 0.9 6.4e-21 74.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDJ61004.1 - 8.8e-05 22.6 0.2 3.2 7.7 0.1 4.3 5 0 0 5 5 5 3 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CDJ61004.1 - 0.002 17.5 0.0 1.8 7.8 0.0 2.7 2 1 0 2 2 2 2 Middle or third domain of peptidase_M16 Inositol_P PF00459.25 CDJ61005.1 - 8.5e-16 58.3 0.0 0.0013 18.3 0.0 4.8 4 1 0 4 4 4 3 Inositol monophosphatase family DDHD PF02862.17 CDJ61005.1 - 0.0016 18.6 13.4 1.4 9.0 3.9 4.3 4 0 0 4 4 4 2 DDHD domain DUF3801 PF12687.7 CDJ61005.1 - 0.095 12.8 22.1 0.052 13.6 4.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3801) CPSF100_C PF13299.6 CDJ61005.1 - 0.3 11.3 26.4 2.4 8.3 8.0 4.4 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal DUF4050 PF13259.6 CDJ61005.1 - 2.6 8.4 28.5 0.51 10.6 3.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4050) Cons_hypoth95 PF03602.15 CDJ61006.1 - 2.1e-07 30.7 0.0 9.1e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Roughex PF06020.11 CDJ61006.1 - 6 5.9 6.4 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Drosophila roughex protein DUF1645 PF07816.11 CDJ61007.1 - 0.0096 16.5 5.3 0.014 16.0 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Spt20 PF12090.8 CDJ61007.1 - 0.029 14.0 1.7 0.038 13.6 1.7 1.1 1 0 0 1 1 1 0 Spt20 family Yip1 PF04893.17 CDJ61007.1 - 0.03 14.1 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Yip1 domain SR-25 PF10500.9 CDJ61007.1 - 0.28 10.8 17.9 1.1 8.8 1.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PAF PF15715.5 CDJ61007.1 - 0.82 10.3 8.9 0.29 11.7 4.4 2.3 2 0 0 2 2 2 0 PCNA-associated factor histone like domain DUF1635 PF07795.11 CDJ61007.1 - 1.8 8.3 5.7 2.4 7.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Dehydrin PF00257.19 CDJ61007.1 - 2.2 8.8 13.7 0.59 10.7 2.9 2.3 2 0 0 2 2 2 0 Dehydrin AF-4 PF05110.13 CDJ61007.1 - 8.5 4.3 15.2 0.074 11.1 3.3 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein AIRS PF00586.24 CDJ61008.1 - 1.4e-10 41.6 2.7 1.4e-10 41.6 2.7 3.6 2 2 0 3 3 3 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 CDJ61008.1 - 5.9e-09 36.2 6.7 2.5e-06 27.7 6.7 3.2 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain SR-25 PF10500.9 CDJ61008.1 - 0.25 10.9 13.6 0.43 10.1 4.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 CDJ61008.1 - 3.4 7.2 25.8 1 8.9 6.5 2.8 3 0 0 3 3 3 0 Spt20 family DivIC PF04977.15 CDJ61010.1 - 9.8e-05 22.0 0.5 0.00015 21.4 0.5 1.3 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.18 CDJ61010.1 - 0.00011 22.3 8.5 0.00069 19.8 1.1 2.0 1 1 1 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 CDJ61010.1 - 0.00016 21.7 2.3 0.00023 21.2 2.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 CDJ61010.1 - 0.0005 20.3 0.3 0.0012 19.1 0.3 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 CDJ61010.1 - 0.00084 19.3 1.8 0.0012 18.8 1.8 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 CDJ61010.1 - 0.0015 18.6 3.1 0.0027 17.8 3.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 CDJ61010.1 - 0.0017 18.5 0.2 0.0022 18.1 0.2 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF2968 PF11180.8 CDJ61010.1 - 0.0017 18.0 0.5 0.0021 17.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) ZapB PF06005.12 CDJ61010.1 - 0.0036 17.7 3.5 0.0053 17.2 3.5 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Nnf1 PF03980.14 CDJ61010.1 - 0.0039 17.6 0.2 0.0045 17.4 0.2 1.3 1 0 0 1 1 1 1 Nnf1 FlaC_arch PF05377.11 CDJ61010.1 - 0.0075 16.6 1.5 0.054 13.9 1.2 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 CDJ61010.1 - 0.0077 16.6 2.1 0.011 16.0 2.1 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain DUF1640 PF07798.11 CDJ61010.1 - 0.008 16.2 0.4 0.015 15.3 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF4140 PF13600.6 CDJ61010.1 - 0.0082 16.6 0.1 0.009 16.4 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) JIP_LZII PF16471.5 CDJ61010.1 - 0.0087 16.2 2.0 0.024 14.8 2.0 1.8 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II DUF2730 PF10805.8 CDJ61010.1 - 0.013 15.6 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) APG6_N PF17675.1 CDJ61010.1 - 0.013 16.0 0.2 0.013 16.0 0.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region MIP-T3_C PF17749.1 CDJ61010.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Macoilin PF09726.9 CDJ61010.1 - 0.017 13.7 0.1 0.017 13.7 0.1 1.0 1 0 0 1 1 1 0 Macoilin family TRAF_BIRC3_bd PF16673.5 CDJ61010.1 - 0.017 14.9 1.2 0.017 14.9 1.2 1.5 2 0 0 2 2 1 0 TNF receptor-associated factor BIRC3 binding domain MbeD_MobD PF04899.12 CDJ61010.1 - 0.018 15.2 1.1 0.036 14.2 1.2 1.5 2 0 0 2 2 1 0 MbeD/MobD like DUF3450 PF11932.8 CDJ61010.1 - 0.022 14.1 1.4 0.028 13.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LPP PF04728.13 CDJ61010.1 - 0.028 14.8 1.5 0.04 14.3 1.5 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Spc7 PF08317.11 CDJ61010.1 - 0.03 13.2 0.1 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CDJ61010.1 - 0.038 14.1 1.2 0.055 13.6 1.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phasin PF05597.11 CDJ61010.1 - 0.04 13.9 0.3 0.62 10.1 0.0 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 CDJ61010.1 - 0.046 13.1 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 CDJ61010.1 - 0.048 13.5 3.5 0.17 11.7 3.5 1.8 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Prominin PF05478.11 CDJ61010.1 - 0.12 10.3 0.1 0.82 7.6 0.4 1.6 1 1 0 1 1 1 0 Prominin NPV_P10 PF05531.12 CDJ61010.1 - 0.16 12.4 0.9 1 9.9 0.2 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Bap31_Bap29_C PF18035.1 CDJ61010.1 - 0.25 11.4 3.1 0.9 9.6 3.3 1.9 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4200 PF13863.6 CDJ61011.1 - 9.3e-24 84.1 12.4 9.3e-24 84.1 12.4 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) THDPS_N_2 PF14805.6 CDJ61011.1 - 0.78 10.0 4.8 3.2 8.1 3.5 2.8 1 1 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Robl_LC7 PF03259.17 CDJ61013.1 - 9.6e-12 44.5 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CDJ61013.1 - 0.0065 16.4 0.0 0.0095 15.8 0.0 1.4 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 CLPTM1 PF05602.12 CDJ61013.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DMPK_coil PF08826.10 CDJ61015.1 - 0.0084 16.2 1.8 0.018 15.2 1.8 1.5 1 0 0 1 1 1 1 DMPK coiled coil domain like MIP-T3_C PF17749.1 CDJ61015.1 - 0.019 15.0 1.1 0.1 12.6 1.0 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 CDJ61015.1 - 0.023 14.9 0.5 0.04 14.1 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.16 CDJ61015.1 - 0.058 13.0 0.4 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF16 PF01519.16 CDJ61015.1 - 0.11 13.0 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 cNMPbd_u2 PF16643.5 CDJ61016.1 - 2 8.8 7.4 0.36 11.3 1.8 2.6 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein DUF4612 PF15389.6 CDJ61017.1 - 0.087 13.9 6.9 0.054 14.6 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) CFTR_R PF14396.6 CDJ61019.1 - 3 7.4 9.8 2.7 7.5 0.3 2.2 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain HrcA PF01628.21 CDJ61020.1 - 0.46 10.3 8.5 0.73 9.7 8.5 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain SprA-related PF12118.8 CDJ61020.1 - 4.3 6.4 27.0 6.4 5.8 22.8 2.1 2 0 0 2 2 2 0 SprA-related family LMBR1 PF04791.16 CDJ61020.1 - 7.5 5.3 8.2 9.4 5.0 8.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Radial_spoke PF04712.12 CDJ61021.1 - 0.00032 19.8 0.0 0.00034 19.7 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein LMBR1 PF04791.16 CDJ61023.1 - 0.0015 17.5 2.6 0.0015 17.5 2.6 2.4 1 1 0 2 2 2 1 LMBR1-like membrane protein RskA PF10099.9 CDJ61023.1 - 0.0074 16.6 14.9 0.0074 16.6 14.9 2.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Wzy_C PF04932.15 CDJ61023.1 - 0.054 13.1 0.4 0.15 11.7 0.4 1.7 1 1 0 1 1 1 0 O-Antigen ligase ABC2_membrane_2 PF12679.7 CDJ61023.1 - 0.12 11.6 0.0 1.9 7.7 0.0 2.3 2 2 0 2 2 2 0 ABC-2 family transporter protein TFIIA PF03153.13 CDJ61023.1 - 0.65 9.9 51.6 0.79 9.6 10.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.12 CDJ61023.1 - 1.1 9.6 11.2 0.76 10.2 2.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.19 CDJ61023.1 - 1.2 9.7 15.5 0.58 10.8 7.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF5338 PF17273.2 CDJ61023.1 - 3.8 7.7 0.0 3.8 7.7 0.0 3.9 4 1 1 5 5 5 0 Family of unknown function (DUF5338) Tweety PF04906.13 CDJ61023.1 - 7.2 5.1 13.1 0.19 10.4 0.7 2.3 2 0 0 2 2 2 0 Tweety Kinesin PF00225.23 CDJ61024.1 - 7.9e-66 222.3 0.0 4.2e-54 183.7 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ61024.1 - 2.3e-13 50.3 0.0 2.2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding AP_endonuc_2 PF01261.24 CDJ61026.1 - 3.4 7.1 4.1 41 3.5 4.1 2.1 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel GYF PF02213.16 CDJ61027.1 - 2.9e-10 39.6 6.1 7.1e-10 38.4 5.4 2.1 2 0 0 2 2 2 1 GYF domain Metallophos PF00149.28 CDJ61028.1 - 1.9e-09 38.3 0.0 2.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_E_B PF04042.16 CDJ61028.1 - 0.0011 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.7 CDJ61028.1 - 0.023 14.9 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Spt20 PF12090.8 CDJ61029.1 - 0.017 14.8 24.3 0.49 10.0 3.0 2.7 2 0 0 2 2 2 0 Spt20 family KHA PF11834.8 CDJ61032.1 - 0.017 15.2 0.5 1.4 9.0 0.1 2.7 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel YjeF_N PF03853.15 CDJ61032.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.5 3 0 0 3 3 3 0 YjeF-related protein N-terminus Connexin PF00029.19 CDJ61034.1 - 0.091 12.5 14.5 0.11 12.2 3.0 3.0 3 0 0 3 3 3 0 Connexin Folliculin PF11704.8 CDJ61034.1 - 0.13 12.2 14.6 4.8 7.0 0.7 3.3 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Dpy-30 PF05186.13 CDJ61034.1 - 0.22 11.3 7.0 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Dpy-30 motif TCP PF03634.13 CDJ61034.1 - 0.39 11.3 23.2 0.77 10.3 11.2 3.3 3 0 0 3 3 3 0 TCP family transcription factor Suf PF05843.14 CDJ61034.1 - 0.83 9.6 23.7 0.52 10.3 3.3 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Coilin_N PF15862.5 CDJ61034.1 - 1.9 8.3 29.7 0.026 14.3 10.3 3.5 3 0 0 3 3 3 0 Coilin N-terminus Spt20 PF12090.8 CDJ61034.1 - 3.5 7.2 54.9 0.031 13.9 2.2 3.3 3 0 0 3 3 3 0 Spt20 family CPSF100_C PF13299.6 CDJ61034.1 - 3.6 7.7 19.8 2 8.6 0.6 3.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 CDJ61034.1 - 3.9 8.1 18.0 11 6.6 3.4 3.5 2 1 1 3 3 3 0 Ctr copper transporter family SprA-related PF12118.8 CDJ61034.1 - 4.6 6.3 41.0 0.38 9.8 16.8 3.4 3 0 0 3 3 3 0 SprA-related family EPL1 PF10513.9 CDJ61034.1 - 5.1 7.5 27.2 1.2 9.5 1.8 3.5 3 0 0 3 3 3 0 Enhancer of polycomb-like RR_TM4-6 PF06459.12 CDJ61034.1 - 5.8 6.7 26.7 3.7 7.3 12.7 3.2 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 CDJ61034.1 - 7.1 6.5 10.3 17 5.3 3.7 3.0 3 0 0 3 3 3 0 N-glycosylation protein SpoIIP PF07454.11 CDJ61034.1 - 7.5 5.9 25.7 1.7 8.0 0.4 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) YABBY PF04690.13 CDJ61034.1 - 9.4 6.8 15.5 1.2 9.7 2.8 3.1 3 0 0 3 3 3 0 YABBY protein DEAD PF00270.29 CDJ61035.1 - 1.7e-18 67.0 0.0 2.2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ61035.1 - 0.0073 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLAG PF03805.13 CDJ61037.1 - 0.00016 19.5 0.0 0.00025 18.8 0.0 1.2 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein TFIIA PF03153.13 CDJ61037.1 - 0.021 14.8 9.6 0.047 13.7 9.6 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF454 PF04304.13 CDJ61037.1 - 0.13 12.3 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Roughex PF06020.11 CDJ61037.1 - 5.1 6.1 9.2 8.4 5.4 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF572 PF04502.13 CDJ61039.1 - 0.02 14.6 12.2 0.024 14.3 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Laminin_G_3 PF13385.6 CDJ61041.1 - 2.2e-24 86.4 0.0 4.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDJ61041.1 - 0.00025 21.6 0.0 0.0009 19.8 0.0 1.9 2 0 0 2 2 2 1 Laminin G domain ACDC PF14733.6 CDJ61042.1 - 9.1e-24 83.6 2.2 9.8e-24 83.5 0.1 2.2 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ61042.1 - 1.7e-06 28.2 4.9 4.5e-06 26.8 4.9 1.8 1 0 0 1 1 1 1 AP2 domain SUIM_assoc PF16619.5 CDJ61042.1 - 2.1 8.5 13.9 0.046 13.8 4.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 CDJ61043.1 - 2.1e-17 63.5 0.3 3.2e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ61043.1 - 0.00039 20.5 0.4 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Y_phosphatase PF00102.27 CDJ61043.1 - 0.064 12.8 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Tim54 PF11711.8 CDJ61043.1 - 0.29 9.9 2.2 0.36 9.6 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 CDJ61043.1 - 0.8 9.3 15.3 0.1 12.2 0.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_A_exo1 PF01612.20 CDJ61044.1 - 2.3e-09 37.2 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DEAD PF00270.29 CDJ61045.1 - 6.2e-25 88.0 31.8 1.9e-24 86.4 5.6 3.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ61045.1 - 0.0011 19.3 6.4 0.0039 17.5 0.1 4.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4239 PF14023.6 CDJ61045.1 - 0.086 12.5 2.5 0.12 12.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Lin-8 PF03353.15 CDJ61045.1 - 3.7 7.0 57.9 0.15 11.6 16.5 4.3 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist RskA PF10099.9 CDJ61046.1 - 0.00098 19.5 4.3 0.0012 19.2 4.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.9 CDJ61046.1 - 0.0039 16.8 1.0 0.0058 16.3 1.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF5423 PF17461.2 CDJ61046.1 - 0.012 14.5 2.6 0.015 14.2 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) TFIIA PF03153.13 CDJ61046.1 - 0.079 13.0 13.3 0.086 12.8 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ61046.1 - 0.12 12.3 3.6 0.13 12.3 3.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3292 PF11696.8 CDJ61046.1 - 0.13 10.6 2.5 0.15 10.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FAM199X PF15814.5 CDJ61046.1 - 0.59 9.1 4.4 0.76 8.8 4.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 CDJ61046.1 - 1.8 7.3 4.2 2 7.1 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF3446 PF11928.8 CDJ61046.1 - 5.1 7.5 12.6 12 6.3 12.6 1.7 1 1 0 1 1 1 0 Early growth response N-terminal domain RskA PF10099.9 CDJ61047.1 - 0.0034 17.7 20.2 0.0034 17.7 20.2 8.1 2 2 3 5 5 5 1 Anti-sigma-K factor rskA RAP1 PF07218.11 CDJ61047.1 - 5.7 5.1 17.7 9.4 4.4 17.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TSP_1 PF00090.19 CDJ61048.1 - 2.2e-05 24.6 11.4 0.036 14.3 1.0 4.7 3 0 0 3 3 3 2 Thrombospondin type 1 domain TSP_1 PF00090.19 CDJ61049.1 - 0.0063 16.7 0.1 0.0063 16.7 0.1 5.9 6 0 0 6 6 6 2 Thrombospondin type 1 domain Meis_PKNOX_N PF16493.5 CDJ61049.1 - 4.6 7.6 6.1 15 6.0 0.2 3.0 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 ORF_12_N PF18042.1 CDJ61050.1 - 0.15 12.5 0.1 0.36 11.3 0.1 1.5 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Gal_Lectin PF02140.18 CDJ61050.1 - 0.32 11.5 9.4 0.47 10.9 3.2 3.3 2 1 1 3 3 3 0 Galactose binding lectin domain EGF PF00008.27 CDJ61050.1 - 2.8 8.3 7.3 16 5.9 0.1 3.6 3 0 0 3 3 3 0 EGF-like domain Nsp1_C PF05064.13 CDJ61052.1 - 1.4e-12 47.4 3.2 1.4e-12 47.4 3.2 1.8 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CDJ61052.1 - 1.8e-06 28.7 146.8 0.44 11.4 13.0 6.9 1 1 4 5 5 5 2 Nucleoporin FG repeat region SPECT1 PF18680.1 CDJ61052.1 - 0.24 11.0 0.1 0.44 10.2 0.1 1.3 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 PI3K_P85_iSH2 PF16454.5 CDJ61052.1 - 1.2 8.7 5.0 2.5 7.7 5.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 CDJ61052.1 - 1.2 9.2 7.2 8.7 6.4 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 CDJ61053.1 - 5.3e-32 111.2 0.0 6.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61053.1 - 1.9e-23 83.1 0.0 2.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDJ61053.1 - 1.6e-10 40.4 0.0 2.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ61053.1 - 0.0012 18.8 0.5 0.029 14.3 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 CDJ61053.1 - 0.025 14.8 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CDJ61053.1 - 0.062 12.3 0.1 0.093 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAM_LAG1_CLN8 PF03798.16 CDJ61055.1 - 3.8e-26 92.1 19.7 5.3e-26 91.6 19.7 1.2 1 0 0 1 1 1 1 TLC domain Septin PF00735.18 CDJ61056.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin DUF572 PF04502.13 CDJ61056.1 - 2.3 7.8 6.7 5 6.7 6.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dynamin_M PF01031.20 CDJ61057.1 - 1.3e-91 306.8 0.0 2.9e-87 292.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CDJ61057.1 - 3.8e-32 111.6 0.0 8.4e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDJ61057.1 - 2.7e-30 104.4 3.6 3.5e-30 104.0 1.9 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain T3SS_needle_E PF08988.10 CDJ61057.1 - 0.024 14.8 2.7 1 9.6 0.1 2.8 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle zf-CW PF07496.15 CDJ61058.1 - 1.1e-36 124.6 38.6 1.9e-12 47.0 8.8 3.9 3 0 0 3 3 3 3 CW-type Zinc Finger Amino_oxidase PF01593.24 CDJ61058.1 - 6.3e-24 85.1 5.9 5.8e-09 35.7 0.0 3.7 3 1 1 4 4 4 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDJ61058.1 - 8.5e-07 29.1 2.7 6e-06 26.4 2.7 2.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ61058.1 - 0.00052 19.3 0.6 0.0012 18.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDJ61058.1 - 0.014 14.1 0.2 0.014 14.1 0.2 2.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 CDJ61058.1 - 0.028 13.5 0.1 0.071 12.1 0.1 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDJ61058.1 - 0.05 12.9 1.4 0.095 11.9 1.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ61058.1 - 0.095 11.9 0.4 0.21 10.8 0.4 1.5 1 0 0 1 1 1 0 Thi4 family PHD PF00628.29 CDJ61058.1 - 0.53 10.2 11.6 7.7 6.5 0.4 4.2 3 1 0 3 3 3 0 PHD-finger Thioredoxin PF00085.20 CDJ61059.1 - 2.7e-24 85.1 0.0 3.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CDJ61059.1 - 6.4e-07 29.0 0.0 7.9e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDJ61059.1 - 1.5e-06 28.6 0.0 2.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDJ61059.1 - 1.4e-05 25.2 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.13 CDJ61059.1 - 0.0034 17.5 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 CDJ61059.1 - 0.0054 17.0 0.0 0.046 14.0 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CDJ61059.1 - 0.0068 16.3 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CDJ61059.1 - 0.025 14.5 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 CDJ61059.1 - 0.028 14.1 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Redoxin TraF PF13728.6 CDJ61059.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein Cnd2 PF05786.14 CDJ61060.1 - 3.5e-23 82.2 2.6 8.9e-22 77.6 8.2 4.9 4 1 0 5 5 5 2 Condensin complex subunit 2 CNDH2_N PF06278.11 CDJ61060.1 - 0.0028 17.8 0.1 0.0028 17.8 0.1 4.8 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Lin-8 PF03353.15 CDJ61060.1 - 2.4 7.6 39.4 1.4 8.4 5.9 3.0 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist Adaptin_N PF01602.20 CDJ61061.1 - 6.6e-15 54.7 0.4 7.1e-15 54.5 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDJ61061.1 - 0.032 14.3 0.1 0.23 11.5 0.1 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDJ61061.1 - 0.052 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats APA3_viroporin PF11289.8 CDJ61062.1 - 0.55 9.8 2.0 0.59 9.6 0.4 1.7 2 0 0 2 2 2 0 Coronavirus accessory protein 3a LRR_2 PF07723.13 CDJ61063.1 - 5.2 7.9 7.6 14 6.5 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat PGM_PMM_I PF02878.16 CDJ61064.1 - 9.3e-10 38.4 0.0 1.6e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RskA PF10099.9 CDJ61064.1 - 0.00023 21.5 3.1 0.00023 21.5 3.1 5.1 2 1 3 5 5 5 1 Anti-sigma-K factor rskA Exonuc_VII_L PF02601.15 CDJ61064.1 - 0.0027 17.4 6.2 0.0027 17.4 6.2 2.3 1 1 1 2 2 2 1 Exonuclease VII, large subunit DUF4486 PF14858.6 CDJ61064.1 - 0.055 12.0 13.3 0.18 10.2 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4486) Zip PF02535.22 CDJ61064.1 - 0.098 11.9 14.3 0.4 9.8 14.4 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter ASD2 PF08687.11 CDJ61064.1 - 0.13 11.8 27.1 0.2 11.2 1.3 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 SARAF PF06682.12 CDJ61064.1 - 1.8 8.2 13.5 0.065 12.9 3.8 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CNDH2_C PF16858.5 CDJ61064.1 - 2.4 7.9 23.1 0.4 10.5 13.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SLC12 PF03522.15 CDJ61064.1 - 2.4 7.1 18.3 1.4 7.9 12.3 2.0 2 0 0 2 2 2 0 Solute carrier family 12 BORG_CEP PF14957.6 CDJ61064.1 - 2.7 9.2 11.0 9.2 7.4 6.8 2.4 2 0 0 2 2 2 0 Cdc42 effector PRP1_N PF06424.12 CDJ61064.1 - 6.3 7.2 20.2 0.7 10.3 10.7 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal AP2 PF00847.20 CDJ61065.1 - 1.7e-15 57.0 11.5 1.7e-10 41.0 0.7 5.5 5 0 0 5 5 5 3 AP2 domain RskA PF10099.9 CDJ61065.1 - 0.031 14.6 0.2 0.031 14.6 0.2 16.0 3 2 7 11 11 11 0 Anti-sigma-K factor rskA SMAP PF15477.6 CDJ61066.1 - 1.7e-11 44.9 0.7 1.7e-11 44.9 0.7 3.6 2 2 1 3 3 3 1 Small acidic protein family Cwf_Cwc_15 PF04889.12 CDJ61066.1 - 0.015 15.1 8.5 0.015 15.1 8.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4050 PF13259.6 CDJ61066.1 - 0.017 15.5 14.9 0.48 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF677 PF05055.12 CDJ61066.1 - 0.019 13.9 1.2 0.027 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Med8 PF10232.9 CDJ61066.1 - 0.91 9.1 9.4 2.2 7.8 9.4 1.8 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1635 PF07795.11 CDJ61066.1 - 5.1 6.9 14.4 22 4.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PIN_12 PF16289.5 CDJ61066.1 - 8.2 6.9 7.4 1.1 9.7 2.2 1.9 2 0 0 2 2 2 0 PIN domain Mg_trans_NIPA PF05653.14 CDJ61067.1 - 5.8e-11 42.1 9.7 1.5e-07 30.9 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Pex2_Pex12 PF04757.14 CDJ61068.1 - 5.9e-22 78.4 7.0 1.3e-21 77.3 7.0 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region Connexin PF00029.19 CDJ61068.1 - 0.004 16.9 1.0 0.0069 16.2 1.0 1.3 1 0 0 1 1 1 1 Connexin Ctr PF04145.15 CDJ61068.1 - 2.2 8.9 5.0 0.88 10.2 0.6 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Syntaxin_2 PF14523.6 CDJ61070.1 - 0.064 13.6 0.6 0.24 11.8 0.6 2.0 1 0 0 1 1 1 0 Syntaxin-like protein Prominin PF05478.11 CDJ61071.1 - 0.086 10.8 0.0 0.11 10.4 0.0 1.0 1 0 0 1 1 1 0 Prominin DASH_Dam1 PF08653.10 CDJ61071.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 PepSY_TM PF03929.16 CDJ61072.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM region SET PF00856.28 CDJ61073.1 - 1.5e-06 28.7 0.0 5e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 SET domain Abhydrolase_2 PF02230.16 CDJ61074.1 - 3.3e-48 164.4 0.0 7.2e-48 163.3 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDJ61074.1 - 6.8e-05 23.6 3.2 0.00015 22.5 0.4 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDJ61074.1 - 0.0005 20.0 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 CDJ61074.1 - 0.00054 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CDJ61074.1 - 0.0031 17.0 0.0 0.74 9.2 0.0 2.6 2 1 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDJ61074.1 - 0.0034 16.7 0.4 0.26 10.5 0.1 2.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDJ61074.1 - 0.0065 16.1 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 CDJ61074.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 CDJ61074.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TPR_9 PF13371.6 CDJ61075.1 - 6.2e-10 39.1 6.3 1.4e-09 37.9 0.9 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ61075.1 - 2.3e-09 37.6 1.5 5.7e-09 36.4 1.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ61075.1 - 2.3e-08 33.5 0.3 0.014 15.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDJ61075.1 - 1.2e-07 31.3 0.1 0.0025 17.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ61075.1 - 3.7e-06 27.5 5.3 0.00078 20.0 0.5 3.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDJ61075.1 - 4.7e-06 27.0 4.2 0.00014 22.3 0.4 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ61075.1 - 0.00049 20.5 1.7 0.0036 17.8 0.2 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ61075.1 - 0.0016 18.5 0.1 0.064 13.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ61075.1 - 0.002 18.4 0.5 0.0058 16.9 0.3 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TMEM52 PF14979.6 CDJ61075.1 - 0.0023 17.9 0.2 0.0053 16.7 0.2 1.5 1 0 0 1 1 1 1 Transmembrane 52 ANAPC3 PF12895.7 CDJ61075.1 - 0.0023 18.1 0.8 0.0023 18.1 0.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CDJ61075.1 - 0.0094 14.9 0.0 0.0094 14.9 0.0 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 CDJ61075.1 - 0.02 14.9 0.9 3.3 7.8 0.1 3.2 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CDJ61075.1 - 0.029 14.7 1.2 0.13 12.6 1.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDJ61075.1 - 0.07 13.8 0.2 0.07 13.8 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ61075.1 - 0.083 13.0 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat DNA_pol_B_thumb PF14791.6 CDJ61078.1 - 0.96 9.7 4.5 8.5 6.6 0.3 3.6 2 0 0 2 2 2 0 DNA polymerase beta thumb Pkinase PF00069.25 CDJ61079.1 - 4.2e-62 209.9 0.0 4.2e-62 209.9 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.29 CDJ61079.1 - 5.8e-58 192.9 1.7 9.3e-20 70.5 0.0 4.9 5 0 0 5 5 4 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CDJ61079.1 - 5.2e-31 107.9 0.0 5.2e-31 107.9 0.0 2.1 2 0 0 2 2 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ61079.1 - 2.6e-06 27.0 0.0 2.6e-06 27.0 0.0 2.1 2 1 0 2 2 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ61079.1 - 9e-05 21.4 1.5 0.091 11.5 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Cupin_2 PF07883.11 CDJ61079.1 - 0.0011 18.7 0.2 3.6 7.4 0.0 4.1 4 0 0 4 4 4 1 Cupin domain AAA_11 PF13086.6 CDJ61079.1 - 0.027 14.3 13.1 0.062 13.1 13.1 1.5 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 CDJ61079.1 - 0.061 12.1 11.6 0.091 11.5 11.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 CDJ61079.1 - 0.081 13.1 8.7 0.14 12.3 8.7 1.4 1 0 0 1 1 1 0 DDHD domain Atg14 PF10186.9 CDJ61079.1 - 0.11 11.6 16.0 0.18 10.8 16.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seadorna_VP7 PF07387.11 CDJ61079.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SET PF00856.28 CDJ61079.1 - 0.35 11.3 1.5 3.3 8.0 2.3 2.2 2 0 0 2 2 2 0 SET domain Zip PF02535.22 CDJ61079.1 - 0.75 8.9 5.0 1.1 8.3 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 CDJ61079.1 - 1.5 8.2 18.1 2.5 7.5 18.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 CDJ61079.1 - 1.5 7.4 14.5 2.7 6.6 14.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0560 PF10577.9 CDJ61079.1 - 2.2 6.7 20.6 3.4 6.0 20.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 CDJ61079.1 - 2.5 5.9 14.6 4.1 5.2 14.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR1 PF08505.10 CDJ61079.1 - 2.7 8.2 23.3 5.7 7.2 23.3 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Band_3_cyto PF07565.13 CDJ61079.1 - 3.5 7.4 12.6 7.4 6.3 12.6 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Asp-B-Hydro_N PF05279.11 CDJ61079.1 - 5.4 7.0 21.4 9.4 6.2 21.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Gti1_Pac2 PF09729.9 CDJ61079.1 - 7.5 6.6 12.7 17 5.5 12.7 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.12 CDJ61079.1 - 9 5.6 30.7 16 4.8 30.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3_zeta PF05091.12 CDJ61079.1 - 9.6 5.1 22.6 14 4.5 22.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lon_C PF05362.13 CDJ61080.1 - 6e-47 159.8 2.5 6.8e-46 156.4 2.5 2.1 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 CDJ61080.1 - 2.8e-06 27.2 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase MSC PF09402.10 CDJ61081.1 - 0.056 12.9 1.8 0.083 12.3 1.0 1.7 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain T7SS_ESX_EspC PF10824.8 CDJ61081.1 - 0.091 13.2 0.2 0.45 11.0 0.2 2.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm PKD_channel PF08016.12 CDJ61081.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Polycystin cation channel Mobilization_B PF17511.2 CDJ61081.1 - 0.79 10.1 3.3 0.4 11.1 0.2 2.1 3 0 0 3 3 3 0 Mobilization protein B DUF5473 PF17567.2 CDJ61082.1 - 0.85 9.9 6.8 0.29 11.4 0.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5473) RabGAP-TBC PF00566.18 CDJ61083.1 - 2.7e-08 33.7 0.1 4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Paf1 PF03985.13 CDJ61084.1 - 4.5 6.2 8.0 10 5.0 8.0 1.5 1 0 0 1 1 1 0 Paf1 CDK2AP PF09806.9 CDJ61085.1 - 0.00018 21.6 9.7 0.00023 21.3 9.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.8 CDJ61085.1 - 0.0095 15.6 12.3 0.013 15.2 12.3 1.2 1 0 0 1 1 1 1 Spt20 family Sec1 PF00995.23 CDJ61085.1 - 0.012 14.9 1.1 0.013 14.7 1.1 1.0 1 0 0 1 1 1 0 Sec1 family Roughex PF06020.11 CDJ61085.1 - 0.016 14.3 3.4 0.024 13.7 3.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF1712 PF08217.11 CDJ61085.1 - 0.062 11.8 4.5 0.071 11.6 4.5 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) TFIIA PF03153.13 CDJ61085.1 - 0.095 12.7 10.5 0.12 12.4 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC24 PF15669.5 CDJ61085.1 - 0.13 12.1 6.4 0.21 11.4 6.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NST1 PF13945.6 CDJ61085.1 - 0.13 12.3 7.5 0.21 11.7 7.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator INO80_Ies4 PF08193.11 CDJ61085.1 - 0.2 11.6 9.6 0.038 14.0 6.3 1.5 1 1 1 2 2 2 0 INO80 complex subunit Ies4 Lin-8 PF03353.15 CDJ61085.1 - 0.8 9.2 6.9 1 8.9 6.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Clr2 PF10383.9 CDJ61085.1 - 5.2 7.8 7.3 20 5.9 7.3 1.8 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 DUF2151 PF10221.9 CDJ61086.1 - 0.17 10.5 17.0 0.2 10.2 17.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 CDJ61086.1 - 4.2 5.5 19.4 5 5.3 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S10 PF00450.22 CDJ61086.1 - 4.6 6.5 17.6 5.2 6.4 17.6 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase Presenilin PF01080.17 CDJ61086.1 - 8 5.1 27.7 12 4.5 27.7 1.3 1 0 0 1 1 1 0 Presenilin Vac7 PF12751.7 CDJ61086.1 - 8.6 5.7 18.8 9.8 5.5 18.8 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 SR-25 PF10500.9 CDJ61087.1 - 2e-11 44.0 22.5 8.6e-05 22.3 10.3 3.1 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ61087.1 - 6.3e-05 22.1 14.3 6.3e-05 22.1 14.3 4.0 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) Pkinase PF00069.25 CDJ61087.1 - 0.0089 15.4 0.0 0.0089 15.4 0.0 3.7 3 1 1 4 4 4 1 Protein kinase domain DUF4179 PF13786.6 CDJ61087.1 - 0.069 13.6 0.1 0.069 13.6 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) PAT1 PF09770.9 CDJ61087.1 - 0.13 10.5 62.5 0.23 9.7 29.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 CDJ61087.1 - 0.38 9.8 31.3 1.1 8.2 0.6 3.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Connexin PF00029.19 CDJ61087.1 - 0.46 10.2 19.1 0.37 10.5 4.9 2.9 3 0 0 3 3 3 0 Connexin TCP PF03634.13 CDJ61087.1 - 2 9.0 42.7 1.3 9.6 14.6 3.2 3 0 0 3 3 3 0 TCP family transcription factor Ribosomal_60s PF00428.19 CDJ61088.1 - 0.03 14.9 8.3 0.03 14.9 8.3 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein TFIIA PF03153.13 CDJ61088.1 - 1.3 8.9 12.4 1.3 8.9 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit POPLD PF08170.12 CDJ61089.1 - 1.2e-16 60.8 0.0 1.2e-16 60.8 0.0 6.7 7 1 1 8 8 8 1 POPLD (NUC188) domain POP1 PF06978.11 CDJ61089.1 - 2.6e-16 60.2 0.2 2.6e-16 60.2 0.2 7.6 7 1 1 8 8 8 2 Ribonucleases P/MRP protein subunit POP1 TFIIA PF03153.13 CDJ61089.1 - 0.0016 18.5 24.3 0.0016 18.5 24.3 6.5 3 2 3 6 6 6 1 Transcription factor IIA, alpha/beta subunit AP3D1 PF06375.11 CDJ61089.1 - 0.041 14.1 0.2 0.041 14.1 0.2 6.3 6 0 0 6 6 6 0 AP-3 complex subunit delta-1 EOS1 PF12326.8 CDJ61089.1 - 0.99 9.3 25.0 12 5.8 0.7 5.8 6 0 0 6 6 6 0 N-glycosylation protein Med15 PF09606.10 CDJ61090.1 - 0.00046 19.0 52.6 0.0015 17.3 14.7 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.19 CDJ61090.1 - 0.016 15.8 26.3 0.016 15.8 26.3 10.4 5 5 1 7 7 7 0 60s Acidic ribosomal protein eIF-3_zeta PF05091.12 CDJ61090.1 - 5.4 5.9 48.7 0.74 8.7 17.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.9 CDJ61091.1 - 0.0012 17.8 12.6 0.0018 17.2 12.6 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Sin_N PF04801.13 CDJ61091.1 - 0.051 12.8 31.9 0.084 12.1 31.9 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Macoilin PF09726.9 CDJ61091.1 - 0.083 11.4 16.5 0.19 10.3 16.5 1.5 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 CDJ61091.1 - 0.11 12.3 24.9 0.016 14.9 20.4 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 Dynactin_p62 PF05502.13 CDJ61091.1 - 0.11 11.3 16.2 0.16 10.7 16.2 1.2 1 0 0 1 1 1 0 Dynactin p62 family DUF442 PF04273.13 CDJ61091.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.3 3 0 0 3 3 2 0 Putative phosphatase (DUF442) Tim54 PF11711.8 CDJ61091.1 - 0.23 10.2 13.3 0.37 9.5 13.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 CDJ61091.1 - 0.23 9.5 15.8 0.34 8.9 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PAT1 PF09770.9 CDJ61091.1 - 0.25 9.5 38.8 0.36 9.1 38.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cellulose_synt PF03552.14 CDJ61091.1 - 0.26 9.7 8.6 5.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Cellulose synthase FHIPEP PF00771.20 CDJ61091.1 - 0.26 9.7 8.4 0.4 9.1 8.4 1.3 1 0 0 1 1 1 0 FHIPEP family DUF4746 PF15928.5 CDJ61091.1 - 0.38 10.1 9.2 0.76 9.1 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF572 PF04502.13 CDJ61091.1 - 0.74 9.4 20.6 0.03 14.0 14.9 1.5 2 0 0 2 2 1 0 Family of unknown function (DUF572) CLN3 PF02487.17 CDJ61091.1 - 0.87 8.6 11.5 1.5 7.8 11.5 1.4 1 0 0 1 1 1 0 CLN3 protein HCO3_cotransp PF00955.21 CDJ61091.1 - 0.89 8.3 6.5 1.3 7.7 6.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family SLC12 PF03522.15 CDJ61091.1 - 1.3 8.0 24.6 2 7.3 24.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PDDEXK_6 PF04720.12 CDJ61091.1 - 1.3 8.9 13.9 2.9 7.8 13.9 1.6 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Dicty_REP PF05086.12 CDJ61091.1 - 3.1 5.7 11.5 4.2 5.2 11.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.11 CDJ61091.1 - 3.6 6.0 18.9 5.5 5.3 18.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Membralin PF09746.9 CDJ61091.1 - 3.9 6.4 11.5 6.1 5.8 11.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein Calici_coat_C PF08435.11 CDJ61091.1 - 4.4 6.8 17.1 8 5.9 17.1 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal GREB1 PF15782.5 CDJ61091.1 - 5 4.1 27.7 6.8 3.7 27.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SARAF PF06682.12 CDJ61091.1 - 5 6.7 24.7 10 5.6 24.7 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MMR1 PF08505.10 CDJ61091.1 - 9.1 6.5 29.7 19 5.4 29.7 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF966 PF06136.13 CDJ61091.1 - 9.4 5.8 20.9 4.3 7.0 17.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Ku PF02735.16 CDJ61092.1 - 0.015 15.0 0.0 0.098 12.3 0.0 2.1 2 0 0 2 2 2 0 Ku70/Ku80 beta-barrel domain Ras PF00071.22 CDJ61093.1 - 8.4e-52 175.0 0.5 3.5e-51 173.0 0.5 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDJ61093.1 - 3.1e-28 98.4 0.5 1.3e-27 96.4 0.1 2.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ61093.1 - 2.7e-10 40.0 0.0 6.6e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDJ61093.1 - 6.1e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDJ61093.1 - 7.7e-07 29.2 0.0 1.6e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDJ61093.1 - 0.00024 20.5 0.1 0.00041 19.8 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 CDJ61093.1 - 0.0029 16.9 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 CDJ61093.1 - 0.0037 16.7 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CDJ61093.1 - 0.014 15.3 0.2 0.14 12.0 0.1 2.3 1 1 2 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 CDJ61093.1 - 0.017 15.1 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 CDJ61093.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CDJ61093.1 - 0.073 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3196 PF11428.8 CDJ61093.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) PduV-EutP PF10662.9 CDJ61093.1 - 0.11 12.2 0.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CDJ61093.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 CDJ61093.1 - 0.13 11.4 0.5 0.36 9.9 0.1 1.8 2 0 0 2 2 2 0 MCM P-loop domain FeoB_N PF02421.18 CDJ61093.1 - 0.13 11.8 0.1 1.3 8.5 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.20 CDJ61093.1 - 0.19 10.9 4.8 0.29 10.3 0.5 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Spt20 PF12090.8 CDJ61094.1 - 8.1 6.0 21.7 0.093 12.3 2.7 3.2 3 0 0 3 3 3 0 Spt20 family RskA PF10099.9 CDJ61097.1 - 1.8e-06 28.4 6.7 1.8e-06 28.4 6.7 3.3 2 1 1 3 3 3 1 Anti-sigma-K factor rskA UAE_UbL PF14732.6 CDJ61098.1 - 6.6e-05 23.4 0.0 6.6e-05 23.4 0.0 2.6 4 0 0 4 4 4 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain BUD22 PF09073.10 CDJ61098.1 - 0.072 12.4 25.2 0.077 12.3 23.6 1.9 1 1 1 2 2 2 0 BUD22 TetR_C_1 PF02909.17 CDJ61098.1 - 0.1 12.4 5.7 0.093 12.5 0.9 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RAP1 PF07218.11 CDJ61098.1 - 0.72 8.1 17.7 1.2 7.4 17.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) OAD_gamma PF04277.13 CDJ61098.1 - 1.2 9.8 12.6 14 6.3 0.1 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain UBA_e1_thiolCys PF10585.9 CDJ61098.1 - 4.3 7.2 33.4 4.2 7.2 27.3 3.0 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site SSP160 PF06933.11 CDJ61098.1 - 8.1 4.5 16.5 12 3.9 16.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Choline_kinase PF01633.20 CDJ61099.1 - 2.6e-11 43.5 0.1 6.5e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase TFIIA PF03153.13 CDJ61099.1 - 0.64 9.9 25.1 1.3 9.0 13.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Asparaginase_2 PF01112.18 CDJ61099.1 - 5.6 5.9 10.8 0.13 11.3 3.8 1.8 2 0 0 2 2 2 0 Asparaginase Activator_LAG-3 PF11498.8 CDJ61100.1 - 0.0016 17.5 17.6 0.0016 17.5 17.6 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 EIF4E-T PF10477.9 CDJ61100.1 - 0.28 9.9 16.4 0.38 9.5 16.4 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E CAF1 PF04857.20 CDJ61100.1 - 0.49 9.5 3.5 0.68 9.1 3.5 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease NHase_alpha PF02979.16 CDJ61100.1 - 0.63 9.3 5.7 7 5.9 1.3 2.9 2 1 0 3 3 3 0 Nitrile hydratase, alpha chain DUF1788 PF08747.11 CDJ61100.1 - 1.6 8.8 5.9 0.85 9.6 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1788) Mcm10 PF09332.11 CDJ61100.1 - 1.9 7.8 18.0 1 8.7 7.4 2.2 2 0 0 2 2 2 0 Mcm10 replication factor DUF3223 PF11523.8 CDJ61101.1 - 3.5e-10 40.6 0.0 1.2e-08 35.7 0.0 3.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3223) Caldesmon PF02029.15 CDJ61101.1 - 1.3e-06 27.5 4.0 1.3e-06 27.5 4.0 15.2 8 4 5 14 14 14 1 Caldesmon Utp14 PF04615.13 CDJ61101.1 - 0.0078 14.8 0.0 0.0078 14.8 0.0 14.2 7 5 4 13 13 13 1 Utp14 protein RskA PF10099.9 CDJ61101.1 - 0.017 15.4 0.0 0.017 15.4 0.0 43.7 17 10 11 30 30 30 0 Anti-sigma-K factor rskA PBP PF01161.20 CDJ61102.1 - 6.8e-17 62.0 0.2 1.7e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PepSY_2 PF13670.6 CDJ61102.1 - 0.012 15.6 4.0 0.012 15.6 4.0 3.3 2 1 2 4 4 4 0 Peptidase propeptide and YPEB domain SpoIIIAH PF12685.7 CDJ61102.1 - 0.022 14.6 15.7 0.37 10.6 10.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Presenilin PF01080.17 CDJ61102.1 - 0.047 12.5 29.0 0.047 12.5 18.9 2.2 2 0 0 2 2 2 0 Presenilin ANXA2R PF15721.5 CDJ61102.1 - 0.082 13.4 0.6 0.082 13.4 0.6 2.7 3 0 0 3 3 3 0 Annexin-2 receptor DUF913 PF06025.12 CDJ61102.1 - 2.8 6.8 12.3 5 6.0 9.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CDJ61102.1 - 4.1 6.5 12.7 2.9 7.0 7.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter HhH-GPD PF00730.25 CDJ61103.1 - 3.5e-20 72.5 0.1 7.8e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Activator_LAG-3 PF11498.8 CDJ61103.1 - 0.044 12.7 16.7 0.071 12.1 16.7 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CDJ61103.1 - 1.5 8.7 26.4 2.1 8.3 26.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Secretin_N_2 PF07655.13 CDJ61103.1 - 5.6 7.6 27.3 12 6.6 8.4 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain OmpH PF03938.14 CDJ61103.1 - 7.6 6.9 17.9 6.7 7.1 15.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RNA_pol_L PF01193.24 CDJ61104.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain MMM1 PF10296.9 CDJ61104.1 - 1.3 8.0 0.0 1.3 8.0 0.0 4.0 3 1 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 Nop14 PF04147.12 CDJ61105.1 - 2.3e-08 32.8 90.3 2.3e-08 32.8 90.3 5.8 4 1 0 4 4 4 3 Nop14-like family Dus PF01207.17 CDJ61106.1 - 4.5e-15 55.5 21.0 2.6e-11 43.2 5.7 5.1 3 2 1 4 4 4 3 Dihydrouridine synthase (Dus) Rad52_Rad22 PF04098.15 CDJ61106.1 - 4.3 7.2 9.0 6.9 6.6 6.5 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Sugar_tr PF00083.24 CDJ61107.1 - 3e-41 141.7 8.4 9.2e-35 120.4 2.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDJ61107.1 - 1.6e-20 73.3 30.1 9.6e-18 64.2 18.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DDHD PF02862.17 CDJ61107.1 - 0.025 14.8 0.2 5.3 7.1 0.0 2.1 2 0 0 2 2 2 0 DDHD domain CLN3 PF02487.17 CDJ61107.1 - 0.065 12.3 0.1 0.065 12.3 0.1 2.4 2 0 0 2 2 2 0 CLN3 protein Tir_receptor_N PF07490.11 CDJ61107.1 - 0.093 12.5 1.9 0.18 11.6 1.9 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus EPL1 PF10513.9 CDJ61107.1 - 0.13 12.7 6.0 0.78 10.1 0.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Toprim_N PF08275.11 CDJ61107.1 - 0.29 11.2 1.5 0.53 10.3 1.5 1.3 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain DUF4834 PF16118.5 CDJ61107.1 - 1.5 9.8 0.0 1.5 9.8 0.0 3.3 3 1 0 3 3 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CDJ61107.1 - 2.6 7.6 32.2 1.2 8.7 15.5 2.1 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 CDJ61107.1 - 8 4.2 9.1 0.18 9.7 0.9 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pex26 PF07163.12 CDJ61107.1 - 8.9 5.5 13.5 0.72 9.1 7.1 2.1 2 0 0 2 2 2 0 Pex26 protein Macoilin PF09726.9 CDJ61108.1 - 2e-05 23.4 7.0 2e-05 23.4 7.0 2.2 2 0 0 2 2 2 1 Macoilin family SPX PF03105.19 CDJ61108.1 - 0.00055 20.0 2.6 0.00055 20.0 2.6 2.2 1 1 0 2 2 2 1 SPX domain Apt1 PF10351.9 CDJ61108.1 - 0.00058 18.8 22.7 0.0017 17.3 7.3 2.3 2 0 0 2 2 2 2 Golgi-body localisation protein domain DUF4614 PF15391.6 CDJ61108.1 - 0.0021 18.1 6.0 0.0021 18.1 6.0 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4614) BUD22 PF09073.10 CDJ61108.1 - 0.0048 16.3 12.8 0.0048 16.3 12.8 2.4 2 0 0 2 2 2 2 BUD22 Ecl1 PF12855.7 CDJ61108.1 - 0.012 16.8 35.2 0.27 12.4 18.1 2.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins SAPS PF04499.15 CDJ61108.1 - 0.11 11.2 8.6 0.069 11.9 3.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein U3_snoRNA_assoc PF08297.11 CDJ61108.1 - 0.66 10.7 0.0 0.66 10.7 0.0 3.8 4 0 0 4 4 4 0 U3 snoRNA associated Tic110 PF16940.5 CDJ61108.1 - 0.9 7.9 3.7 1.5 7.2 3.7 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter SLC12 PF03522.15 CDJ61108.1 - 7 5.5 14.0 1.9 7.5 8.3 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Afi1 PF07792.12 CDJ61109.1 - 0.014 15.9 8.4 0.014 15.9 8.4 6.6 2 2 3 5 5 5 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2722 PF10846.8 CDJ61110.1 - 0.013 14.5 8.9 4.5 6.1 8.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) tRNA-synt_1 PF00133.22 CDJ61111.1 - 2.4e-16 59.1 50.8 7.3e-09 34.4 1.6 8.8 6 1 3 9 9 9 6 tRNA synthetases class I (I, L, M and V) RskA PF10099.9 CDJ61111.1 - 0.0047 17.2 13.4 0.0047 17.2 13.4 12.5 4 2 4 10 10 10 3 Anti-sigma-K factor rskA RskA PF10099.9 CDJ61112.1 - 0.00063 20.1 17.5 0.00063 20.1 17.5 3.9 1 1 2 3 3 3 1 Anti-sigma-K factor rskA PAT1 PF09770.9 CDJ61112.1 - 0.2 9.9 41.9 0.35 9.1 41.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRP8_domainIV PF12134.8 CDJ61114.1 - 9.7e-125 414.7 0.8 1.5e-124 414.1 0.8 1.3 1 0 0 1 1 1 1 PRP8 domain IV core Glyco_transf_92 PF01697.27 CDJ61114.1 - 0.024 14.3 0.1 0.052 13.2 0.1 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 92 DUF775 PF05603.12 CDJ61114.1 - 0.096 12.2 1.1 0.15 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ribosomal_60s PF00428.19 CDJ61115.1 - 0.0047 17.5 12.8 0.0047 17.5 12.8 4.7 3 1 1 4 4 4 1 60s Acidic ribosomal protein Borrelia_P83 PF05262.11 CDJ61115.1 - 0.037 12.5 3.9 0.053 12.0 3.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TetR_C_15 PF17918.1 CDJ61115.1 - 0.46 11.3 4.6 1.7 9.4 0.8 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain OATP PF03137.20 CDJ61116.1 - 9.9e-12 43.9 0.1 1.8e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.13 CDJ61116.1 - 0.023 15.4 26.0 0.046 14.4 9.7 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 CDJ61116.1 - 0.037 14.4 1.1 0.037 14.4 1.1 2.4 3 0 0 3 3 2 0 Enhancer of polycomb-like FAM60A PF15396.6 CDJ61116.1 - 0.047 13.7 4.6 6.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A PTPRCAP PF15713.5 CDJ61116.1 - 0.06 13.6 13.0 0.027 14.8 3.4 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF4050 PF13259.6 CDJ61116.1 - 0.25 11.6 10.6 0.13 12.6 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Presenilin PF01080.17 CDJ61116.1 - 0.71 8.6 13.4 0.06 12.1 0.5 3.1 3 0 0 3 3 3 0 Presenilin CPSF100_C PF13299.6 CDJ61116.1 - 0.98 9.6 10.2 0.67 10.1 2.3 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CDJ61116.1 - 1 8.7 7.9 0.46 9.9 2.5 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 CDJ61116.1 - 3.2 7.3 41.1 0.21 11.2 17.3 3.3 3 0 0 3 3 3 0 Spt20 family EIIBC-GUT_N PF03612.14 CDJ61116.1 - 4.3 7.0 9.8 0.86 9.3 2.8 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF719 PF05334.13 CDJ61116.1 - 6.6 6.9 9.7 5.4 7.2 2.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF719) RR_TM4-6 PF06459.12 CDJ61116.1 - 9.9 5.9 13.2 0.84 9.4 3.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FYTT PF07078.11 CDJ61118.1 - 0.00011 21.7 1.0 0.00015 21.2 1.0 1.2 1 0 0 1 1 1 1 Forty-two-three protein DUF2722 PF10846.8 CDJ61118.1 - 0.00019 20.5 0.7 0.00019 20.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RRM_1 PF00076.22 CDJ61118.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC_CDC26 PF10471.9 CDJ61118.1 - 0.00073 20.3 6.9 0.0012 19.6 6.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Limkain-b1 PF11608.8 CDJ61118.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 DUF4770 PF15994.5 CDJ61118.1 - 0.17 12.1 3.6 0.24 11.6 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Spt20 PF12090.8 CDJ61118.1 - 0.72 9.4 14.5 0.89 9.1 14.5 1.1 1 0 0 1 1 1 0 Spt20 family PKI PF02827.16 CDJ61118.1 - 6.1 7.1 8.5 3.7 7.8 6.2 1.7 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF2052 PF09747.9 CDJ61119.1 - 1.7e-26 93.6 96.7 2.6e-14 53.8 28.3 4.2 2 1 2 4 4 4 3 Coiled-coil domain containing protein (DUF2052) RNase_PH PF01138.21 CDJ61120.1 - 2e-05 25.1 0.5 7.5e-05 23.2 0.5 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF726 PF05277.12 CDJ61120.1 - 0.19 10.6 1.3 0.39 9.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) SID-1_RNA_chan PF13965.6 CDJ61120.1 - 8.4 4.7 6.3 12 4.2 0.2 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4471 PF14740.6 CDJ61121.1 - 0.0084 15.4 0.7 0.0084 15.4 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) GBP_C PF02841.14 CDJ61121.1 - 1.5 8.1 27.6 0.073 12.5 19.4 2.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain tRNA_synt_1c_R2 PF04557.15 CDJ61123.1 - 0.1 13.5 0.2 0.1 13.5 0.2 3.0 2 1 1 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PepSY_TM PF03929.16 CDJ61123.1 - 0.22 11.1 12.5 0.57 9.8 1.4 2.1 2 0 0 2 2 2 0 PepSY-associated TM region Spore_coat_CotO PF14153.6 CDJ61123.1 - 0.49 10.3 30.2 0.062 13.2 9.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Rtf2 PF04641.12 CDJ61123.1 - 0.55 9.5 13.7 0.47 9.8 2.2 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger SARAF PF06682.12 CDJ61123.1 - 0.63 9.6 17.0 1.7 8.2 10.1 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis RR_TM4-6 PF06459.12 CDJ61123.1 - 0.83 9.4 20.8 0.34 10.7 6.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MDM31_MDM32 PF08118.11 CDJ61123.1 - 5 5.7 11.7 2 7.0 2.8 2.1 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins ORC_WH_C PF18137.1 CDJ61123.1 - 6 6.9 18.2 5.8 7.0 4.5 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal UPF0239 PF06783.11 CDJ61123.1 - 9 6.6 12.5 0.4 10.9 1.4 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) G0-G1_switch_2 PF15103.6 CDJ61123.1 - 9.2 6.8 15.9 1.6 9.2 3.7 3.1 3 0 0 3 3 3 0 G0/G1 switch protein 2 Hist_deacetyl PF00850.19 CDJ61124.1 - 4e-47 161.2 0.1 6.5e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.32 CDJ61125.1 - 2e-41 139.2 25.4 1.2e-09 38.6 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ61125.1 - 5.4e-05 23.4 1.0 1 9.7 0.0 3.5 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDJ61125.1 - 0.00048 19.5 0.0 1 8.6 0.0 2.6 2 1 1 3 3 3 3 WD40-like domain Nup160 PF11715.8 CDJ61125.1 - 0.021 13.5 9.2 0.055 12.1 0.4 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDJ61125.1 - 0.033 13.2 0.0 3 6.7 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Adeno_terminal PF02459.15 CDJ61125.1 - 0.064 11.7 0.1 0.083 11.3 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein tRNA-synt_1 PF00133.22 CDJ61126.1 - 6.9e-61 206.2 0.0 4.9e-23 81.2 0.0 5.3 5 0 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDJ61126.1 - 7.8e-17 61.6 0.0 1.5e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDJ61126.1 - 9.3e-10 37.8 0.0 1.3e-06 27.4 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 CDJ61126.1 - 0.33 10.8 2.9 1.8 8.5 0.6 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2012 PF09430.10 CDJ61127.1 - 1.8e-11 44.2 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) TarH PF02203.15 CDJ61127.1 - 0.081 12.8 1.0 10 6.0 0.1 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue OTU PF02338.19 CDJ61128.1 - 0.00018 22.0 0.1 0.0016 18.9 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDJ61128.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain SHR-BD PF06650.12 CDJ61129.1 - 3.3e-08 33.3 0.0 1.1e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Kelch_4 PF13418.6 CDJ61130.1 - 1.7e-07 31.1 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ61130.1 - 3.2e-06 26.6 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 CDJ61130.1 - 8.6e-06 25.9 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDJ61130.1 - 0.00098 19.0 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CDJ61130.1 - 0.0019 18.1 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CDJ61130.1 - 0.11 12.8 0.2 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain adh_short_C2 PF13561.6 CDJ61131.1 - 4.8e-06 26.3 0.0 6.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDJ61131.1 - 8.3e-05 22.1 0.0 0.00012 21.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase ORC2 PF04084.14 CDJ61132.1 - 1.5e-30 106.3 0.0 7.9e-30 103.9 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Nup35_RRM PF05172.13 CDJ61132.1 - 0.14 12.1 0.0 0.94 9.5 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif IMUP PF15761.5 CDJ61132.1 - 2.5 8.8 9.9 9.5 7.0 0.8 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein RT_RNaseH PF17917.1 CDJ61133.1 - 0.00046 20.4 0.0 0.00066 19.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CDJ61134.1 - 2.2e-07 30.7 0.0 4.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAP206 PF12018.8 CDJ61136.1 - 0.057 12.9 0.0 0.059 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function Flagellin_N PF00669.20 CDJ61138.1 - 0.39 10.8 7.0 4.8 7.3 7.9 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region NUFIP2 PF15293.6 CDJ61138.1 - 3.4 6.5 21.0 4.4 6.1 21.0 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Cwf_Cwc_15 PF04889.12 CDJ61139.1 - 1.4e-40 139.6 13.1 2.1e-40 139.0 13.1 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Bestrophin PF01062.21 CDJ61139.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Histone_HNS PF00816.21 CDJ61139.1 - 0.048 14.5 12.3 0.63 10.9 2.5 2.5 2 1 0 2 2 2 0 H-NS histone family PAC1 PF16094.5 CDJ61139.1 - 0.41 9.7 3.6 0.37 9.9 0.9 1.9 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 PA26 PF04636.13 CDJ61139.1 - 0.98 8.3 3.4 0.94 8.3 2.7 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) Kinesin_assoc PF16183.5 CDJ61139.1 - 2.7 8.1 6.8 5.1 7.2 6.4 1.8 1 1 0 1 1 1 0 Kinesin-associated DUF3450 PF11932.8 CDJ61139.1 - 4.8 6.4 16.2 0.051 12.9 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) End3 PF12761.7 CDJ61139.1 - 7.9 6.6 13.4 0.43 10.7 6.8 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Methyltransf_16 PF10294.9 CDJ61143.1 - 3.5e-06 26.9 0.0 5.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase IPK PF03770.16 CDJ61144.1 - 1.7e-25 90.0 6.8 5e-15 55.9 0.0 2.9 4 0 0 4 4 4 2 Inositol polyphosphate kinase Glyco_transf_20 PF00982.21 CDJ61145.1 - 6.8e-105 351.5 0.0 9.6e-105 351.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDJ61145.1 - 2.9e-50 170.6 0.0 5e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 CDJ61145.1 - 5.7e-17 61.4 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.12 CDJ61145.1 - 0.00018 21.4 0.0 0.00054 19.8 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PTPA PF03095.15 CDJ61146.1 - 2e-62 211.4 0.0 2.5e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TPR_1 PF00515.28 CDJ61147.1 - 2.7e-10 39.6 0.7 0.00061 19.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ61147.1 - 5.7e-08 32.3 1.1 0.0099 15.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Prenyltrans PF00432.21 CDJ61147.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF4239 PF14023.6 CDJ61147.1 - 2.2 7.9 5.6 5.7 6.6 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DFP PF04127.15 CDJ61148.1 - 1.2e-13 51.3 9.2 2.3e-09 37.3 0.0 3.7 4 0 0 4 4 4 3 DNA / pantothenate metabolism flavoprotein RAP1 PF07218.11 CDJ61148.1 - 0.71 8.1 3.6 1.2 7.3 3.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol3_gamma3 PF12169.8 CDJ61149.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DUF3106 PF11304.8 CDJ61149.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) PhoR PF11808.8 CDJ61149.1 - 2.7 8.4 5.1 1.5 9.3 0.2 2.4 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR CDC50 PF03381.15 CDJ61150.1 - 3.3e-62 210.5 0.0 4.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CitT PF12431.8 CDJ61151.1 - 0.065 13.6 0.2 19 5.7 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulator WW_FCH_linker PF16623.5 CDJ61151.1 - 0.089 13.6 0.5 0.21 12.4 0.1 1.7 1 1 1 2 2 2 0 Unstructured linker region between on GAS7 protein HTH_15 PF12324.8 CDJ61151.1 - 0.15 12.0 1.3 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Spt20 PF12090.8 CDJ61153.1 - 0.026 14.1 1.3 0.026 14.1 1.3 1.5 2 0 0 2 2 2 0 Spt20 family DUF4710 PF15828.5 CDJ61153.1 - 0.17 12.0 2.1 0.32 11.1 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Skp1_POZ PF03931.15 CDJ61154.1 - 8.1e-20 70.8 0.2 1.5e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CDJ61154.1 - 7.9e-19 67.5 0.0 1.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain RNA_pol_Rpc34 PF05158.12 CDJ61155.1 - 3.3e-35 122.0 0.2 2.9e-26 92.7 0.0 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RT_RNaseH PF17917.1 CDJ61155.1 - 2e-10 40.9 0.1 3.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDJ61155.1 - 0.037 14.1 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase UBA_3 PF09288.10 CDJ61155.1 - 0.062 13.1 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Hydrolase_3 PF08282.12 CDJ61159.1 - 1.3e-43 149.6 0.0 1.6e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ61159.1 - 1.8e-06 27.7 0.0 3.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 CDJ61159.1 - 0.16 12.0 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PFK PF00365.20 CDJ61160.1 - 3.1e-54 184.2 0.1 8e-34 117.3 0.1 3.3 4 0 0 4 4 4 3 Phosphofructokinase T3SS_HrpK1 PF16937.5 CDJ61160.1 - 0.24 11.0 0.1 0.43 10.2 0.1 1.2 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF SR-25 PF10500.9 CDJ61161.1 - 0.00037 20.2 10.8 0.00052 19.7 10.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 CDJ61161.1 - 0.1 12.5 4.6 0.15 12.0 4.6 1.2 1 0 0 1 1 1 0 Serglycin Period_C PF12114.8 CDJ61161.1 - 0.11 12.1 11.3 0.18 11.4 11.3 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CCDC106 PF15794.5 CDJ61161.1 - 0.31 10.7 2.6 0.46 10.1 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF515 PF04415.12 CDJ61161.1 - 1.7 6.9 6.9 2.2 6.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HEAT_EZ PF13513.6 CDJ61161.1 - 5.9 7.5 14.4 0.34 11.4 5.6 2.6 2 0 0 2 2 2 0 HEAT-like repeat SR-25 PF10500.9 CDJ61162.1 - 9.5e-06 25.4 10.3 1.1e-05 25.1 10.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CDJ61162.1 - 0.012 15.7 9.8 0.016 15.3 9.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PI3K_1B_p101 PF10486.9 CDJ61162.1 - 0.073 10.9 19.4 0.087 10.6 19.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit IMUP PF15761.5 CDJ61162.1 - 0.092 13.5 14.9 0.074 13.8 13.4 1.6 1 1 0 1 1 1 0 Immortalisation up-regulated protein DUF3446 PF11928.8 CDJ61162.1 - 0.16 12.3 11.1 0.31 11.4 11.1 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain SLAIN PF15301.6 CDJ61162.1 - 1.2 8.3 15.8 1.6 7.9 15.8 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Macoilin PF09726.9 CDJ61162.1 - 2.1 6.8 11.8 2.7 6.5 11.8 1.2 1 0 0 1 1 1 0 Macoilin family Protamine_P2 PF00841.19 CDJ61162.1 - 3.1 8.3 11.8 2.4 8.7 0.3 2.3 2 0 0 2 2 2 0 Sperm histone P2 GEN1_C PF18380.1 CDJ61162.1 - 4.6 8.2 21.6 1.8 9.5 6.7 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF755 PF05501.11 CDJ61162.1 - 6.9 7.0 17.8 0.85 9.9 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Apt1 PF10351.9 CDJ61162.1 - 8.2 5.2 15.7 8.9 5.0 15.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3292 PF11696.8 CDJ61162.1 - 9.3 4.5 10.1 3.3 6.0 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) SDA1 PF05285.12 CDJ61162.1 - 9.4 5.6 33.2 13 5.0 33.2 1.3 1 0 0 1 1 1 0 SDA1 Arf PF00025.21 CDJ61163.1 - 3.7e-20 72.1 0.1 1.6e-12 47.2 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDJ61163.1 - 1.6e-05 25.1 0.5 1.6e-05 25.1 0.5 3.2 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDJ61163.1 - 0.0025 17.4 0.3 0.025 14.2 0.0 2.3 1 1 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 CDJ61163.1 - 0.0038 16.6 0.0 0.0038 16.6 0.0 2.6 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDJ61163.1 - 0.0058 16.1 5.3 0.037 13.4 1.0 3.2 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Vmethyltransf PF01660.17 CDJ61163.1 - 0.057 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral methyltransferase AAA_18 PF13238.6 CDJ61163.1 - 0.062 13.9 1.7 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDJ61163.1 - 0.11 13.0 0.0 0.11 13.0 0.0 3.1 2 1 1 3 3 3 0 ABC transporter G-alpha PF00503.20 CDJ61163.1 - 0.79 8.8 15.9 0.16 11.1 0.6 3.3 3 1 0 3 3 3 0 G-protein alpha subunit RRM_1 PF00076.22 CDJ61164.1 - 5.2e-11 42.2 0.0 7.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 CDJ61164.1 - 0.39 10.3 7.0 0.54 9.8 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rsm1 PF08600.10 CDJ61164.1 - 0.67 10.2 3.4 2.7 8.2 2.0 2.1 1 1 1 2 2 2 0 Rsm1-like Acetyltransf_10 PF13673.7 CDJ61165.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDJ61165.1 - 2.3e-05 24.7 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDJ61165.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CDJ61165.1 - 0.0022 18.1 0.1 0.0038 17.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDJ61165.1 - 0.006 16.8 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SUIM_assoc PF16619.5 CDJ61165.1 - 0.0097 16.0 16.7 0.85 9.7 0.8 3.4 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 MF_alpha_N PF05436.11 CDJ61165.1 - 0.2 11.6 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus RskA PF10099.9 CDJ61166.1 - 5.9e-05 23.4 27.1 0.00039 20.8 13.7 9.7 4 4 3 8 8 8 3 Anti-sigma-K factor rskA SNF PF00209.18 CDJ61167.1 - 7.6e-07 28.2 13.8 1.3e-06 27.4 13.8 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Fez1 PF06818.15 CDJ61168.1 - 1.7 9.1 29.4 0.14 12.6 4.2 3.0 3 0 0 3 3 3 0 Fez1 TMF_TATA_bd PF12325.8 CDJ61168.1 - 3.8 7.7 29.1 0.091 13.0 8.8 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ribosomal_L20 PF00453.18 CDJ61168.1 - 5.3 7.2 8.8 0.36 10.9 2.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L20 SF-assemblin PF06705.11 CDJ61170.1 - 6.7e-26 91.1 12.7 3.9e-19 69.0 9.1 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin SHE3 PF17078.5 CDJ61170.1 - 0.0088 15.8 2.4 0.024 14.3 2.4 1.7 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 CCDC144C PF14915.6 CDJ61170.1 - 0.027 13.6 11.3 0.041 13.0 4.3 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF2408 PF10303.9 CDJ61170.1 - 0.2 12.2 5.6 0.2 12.2 0.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) ApoLp-III PF07464.11 CDJ61170.1 - 0.37 10.9 4.1 0.84 9.7 0.2 2.3 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Pex19 PF04614.12 CDJ61170.1 - 0.63 9.8 4.9 0.99 9.1 4.9 1.3 1 0 0 1 1 1 0 Pex19 protein family Exonuc_VII_L PF02601.15 CDJ61170.1 - 1 8.9 10.0 2 7.9 10.0 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 CDJ61170.1 - 1.1 9.1 20.6 0.081 12.8 2.0 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2018 PF09442.10 CDJ61170.1 - 1.3 10.0 4.4 4.4 8.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2018) Uds1 PF15456.6 CDJ61170.1 - 3.4 7.8 13.4 11 6.2 9.4 2.8 1 1 1 2 2 2 0 Up-regulated During Septation MCU PF04678.13 CDJ61170.1 - 8.4 6.4 8.2 15 5.7 2.7 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter zf-C2H2 PF00096.26 CDJ61171.1 - 7e-05 23.1 0.4 0.00013 22.2 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CDJ61171.1 - 0.0023 18.6 2.4 0.0069 17.1 0.0 2.3 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats XPA_N PF01286.18 CDJ61171.1 - 0.0048 16.9 0.1 0.0079 16.2 0.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal DUF5320 PF17253.2 CDJ61171.1 - 0.016 16.3 1.9 1.2 10.2 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) zf-C2H2_4 PF13894.6 CDJ61171.1 - 0.019 15.8 0.3 0.041 14.7 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDJ61171.1 - 0.046 14.0 0.8 0.11 12.8 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PEP-utilisers_N PF05524.13 CDJ61171.1 - 0.39 10.9 3.8 5.1 7.3 1.2 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal ARS2 PF04959.13 CDJ61171.1 - 0.39 11.1 5.9 7.3 6.9 5.5 2.6 1 1 0 1 1 1 0 Arsenite-resistance protein 2 TFIIA PF03153.13 CDJ61171.1 - 1 9.3 20.5 1.9 8.4 20.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 CDJ61171.1 - 1.2 8.0 21.0 0.028 13.4 13.5 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4140 PF13600.6 CDJ61171.1 - 2.2 8.8 9.0 7.4 7.1 1.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tweety PF04906.13 CDJ61171.1 - 9.9 4.7 8.5 4 6.0 2.7 2.0 2 0 0 2 2 2 0 Tweety MORN PF02493.20 CDJ61173.1 - 4.9e-16 57.6 22.5 1.6e-05 24.5 0.9 5.2 5 0 0 5 5 5 4 MORN repeat Ephrin_rec_like PF07699.13 CDJ61175.1 - 0.35 10.7 39.8 0.025 14.3 5.4 5.5 4 1 1 5 5 5 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 CDJ61176.1 - 0.014 15.2 5.1 0.014 15.2 5.1 5.3 3 2 3 6 6 6 0 Putative ephrin-receptor like COA2 PF17051.5 CDJ61176.1 - 2.6 8.2 3.8 29 4.8 0.2 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 CarboxypepD_reg PF13620.6 CDJ61177.1 - 0.022 15.0 0.3 0.68 10.2 0.0 3.2 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain Pkinase PF00069.25 CDJ61178.1 - 1e-19 71.0 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61178.1 - 8.4e-13 48.2 0.0 9.7e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_9 PF14580.6 CDJ61180.1 - 4.5e-16 58.8 0.0 4.1e-07 29.7 0.0 3.1 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 CDJ61180.1 - 1.2e-11 44.6 6.6 3e-06 27.4 0.6 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ61180.1 - 2.6e-07 30.3 6.1 0.006 16.3 0.6 4.5 2 2 0 3 3 3 3 Leucine rich repeat TolA_bind_tri PF16331.5 CDJ61181.1 - 0.014 15.5 0.8 0.014 15.5 0.8 9.9 5 1 5 10 10 10 0 TolA binding protein trimerisation AP2 PF00847.20 CDJ61181.1 - 0.04 14.1 0.1 0.16 12.2 0.1 2.1 1 0 0 1 1 1 0 AP2 domain EF-hand_6 PF13405.6 CDJ61182.1 - 2.4e-17 61.3 1.5 3.2e-07 29.7 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDJ61182.1 - 2.7e-16 57.8 0.8 9.6e-07 27.9 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDJ61182.1 - 3.2e-15 56.3 0.5 1.3e-08 35.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDJ61182.1 - 6.2e-12 45.7 0.0 5.4e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDJ61182.1 - 1.1e-09 37.4 0.3 2.5e-05 23.5 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDJ61182.1 - 9e-07 28.7 0.1 0.00042 20.1 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair LNS2 PF08235.13 CDJ61183.1 - 2.3e-94 315.1 0.0 3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDJ61183.1 - 1.9e-29 101.6 0.0 3.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CDJ61183.1 - 1.4e-20 73.3 0.0 2.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain RRM_1 PF00076.22 CDJ61185.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cNMP_binding PF00027.29 CDJ61186.1 - 1e-57 192.1 0.3 2.7e-19 69.0 0.0 4.7 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain EF-hand_7 PF13499.6 CDJ61186.1 - 3.4e-05 24.2 0.1 0.88 10.1 0.0 4.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CDJ61186.1 - 6.5e-05 22.2 1.6 0.35 10.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ61186.1 - 8.9e-05 22.1 1.6 0.56 10.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDJ61186.1 - 0.033 14.0 2.2 6.6 6.7 0.2 3.4 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_11 PF08976.11 CDJ61186.1 - 0.074 13.9 0.0 0.31 11.9 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Shugoshin_N PF07558.11 CDJ61186.1 - 0.15 12.0 3.9 34 4.4 0.0 4.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region cNMP_binding PF00027.29 CDJ61187.1 - 2e-22 79.1 0.2 1.1e-14 54.2 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LOR PF04525.12 CDJ61188.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 LURP-one-related PVL_ORF50 PF07768.11 CDJ61188.1 - 3 8.2 8.8 0.22 11.8 3.5 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Phosphodiest PF01663.22 CDJ61189.1 - 0.00041 20.1 0.0 0.00066 19.4 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pox_A_type_inc PF04508.12 CDJ61190.1 - 4.7 7.2 14.7 0.7 9.8 0.7 4.3 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat zf-RING_2 PF13639.6 CDJ61191.1 - 1e-11 45.0 7.9 1.6e-11 44.3 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDJ61191.1 - 5.1e-10 38.9 6.1 1.1e-09 37.9 6.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDJ61191.1 - 1.2e-07 31.4 6.9 1.9e-07 30.8 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDJ61191.1 - 3.1e-06 27.4 6.9 7.9e-06 26.1 6.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDJ61191.1 - 5.6e-06 26.1 7.4 9.6e-06 25.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ61191.1 - 6.5e-06 26.1 1.3 1.6e-05 24.8 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ61191.1 - 1.9e-05 24.6 5.5 4.1e-05 23.5 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDJ61191.1 - 0.00016 21.6 5.5 0.00026 20.9 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDJ61191.1 - 0.00056 19.5 5.0 0.00097 18.7 5.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CDJ61191.1 - 0.0013 18.5 4.5 0.002 17.9 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDJ61191.1 - 0.0032 17.3 2.6 0.0071 16.1 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CDJ61191.1 - 0.03 14.2 6.5 0.058 13.3 6.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 CDJ61191.1 - 0.044 13.9 6.3 0.099 12.8 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CDJ61191.1 - 0.24 11.6 6.1 0.59 10.3 6.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CDJ61191.1 - 0.31 11.4 5.1 0.56 10.6 5.1 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CDJ61191.1 - 1.2 9.3 7.6 5.3 7.3 7.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CDJ61191.1 - 2.7 8.0 5.1 4.4 7.3 5.1 1.4 1 0 0 1 1 1 0 PHD-finger C2 PF00168.30 CDJ61192.1 - 8.7e-37 125.6 0.0 2.1e-09 37.6 0.0 6.9 7 0 0 7 7 7 6 C2 domain FerI PF08151.12 CDJ61192.1 - 0.18 11.9 0.0 0.87 9.7 0.0 2.0 2 0 0 2 2 2 0 FerI (NUC094) domain DNA_pol_E_B PF04042.16 CDJ61193.1 - 4.6e-21 75.1 2.0 3.2e-20 72.4 1.0 2.6 2 1 1 3 3 3 1 DNA polymerase alpha/epsilon subunit B Phage_endo_I PF05367.11 CDJ61193.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage endonuclease I HEAT PF02985.22 CDJ61194.1 - 0.081 13.2 0.8 24 5.5 0.0 4.4 2 0 0 2 2 2 0 HEAT repeat BLIP PF07467.11 CDJ61194.1 - 0.096 13.3 0.1 0.096 13.3 0.1 2.7 3 0 0 3 3 3 0 Beta-lactamase inhibitor (BLIP) zf-C3H1 PF10650.9 CDJ61196.1 - 0.23 11.2 0.4 0.23 11.2 0.4 2.5 3 0 0 3 3 3 0 Putative zinc-finger domain Nodulin_late PF07127.11 CDJ61196.1 - 0.64 10.4 0.1 0.64 10.4 0.1 1.9 2 0 0 2 2 2 0 Late nodulin protein RPN2_C PF18004.1 CDJ61197.1 - 0.0032 17.4 19.6 0.0036 17.2 19.6 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 CDJ61197.1 - 0.0085 14.9 17.2 0.0094 14.8 17.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 CDJ61197.1 - 0.0089 16.2 27.2 0.011 15.8 27.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Merozoite_SPAM PF07133.11 CDJ61197.1 - 0.0093 16.0 21.1 0.011 15.8 21.1 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) TRAP_alpha PF03896.16 CDJ61197.1 - 0.031 13.5 9.7 0.035 13.3 9.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 CDJ61197.1 - 0.034 13.4 9.5 0.038 13.2 9.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CDJ61197.1 - 0.047 12.0 19.7 0.044 12.1 19.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CDJ61197.1 - 0.076 13.4 10.2 0.12 12.8 10.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kei1 PF08552.11 CDJ61197.1 - 0.18 11.7 6.8 0.23 11.3 6.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NPR3 PF03666.13 CDJ61197.1 - 0.26 10.0 16.7 0.29 9.9 16.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OATP PF03137.20 CDJ61197.1 - 0.26 9.5 8.1 0.36 9.1 8.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CSG2 PF16965.5 CDJ61197.1 - 0.3 10.0 8.2 0.37 9.7 8.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF913 PF06025.12 CDJ61197.1 - 0.34 9.8 12.3 0.35 9.8 12.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TraV PF09676.10 CDJ61197.1 - 0.51 11.3 13.0 0.68 10.9 13.0 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) SID-1_RNA_chan PF13965.6 CDJ61197.1 - 0.59 8.5 12.3 0.66 8.3 12.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpc4 PF05132.14 CDJ61197.1 - 0.72 10.3 16.8 1.1 9.7 16.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 CDJ61197.1 - 0.74 9.6 15.0 0.98 9.2 15.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2151 PF10221.9 CDJ61197.1 - 1 7.9 15.8 1.1 7.8 15.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CobT PF06213.12 CDJ61197.1 - 1.4 8.3 33.6 2.1 7.7 33.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CCSAP PF15748.5 CDJ61197.1 - 1.5 9.0 23.4 1.7 8.8 23.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ALMT PF11744.8 CDJ61197.1 - 1.7 7.4 14.9 2.1 7.1 14.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2370 PF10176.9 CDJ61197.1 - 2 8.0 9.0 2.4 7.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2828 PF11443.8 CDJ61197.1 - 2 6.4 21.8 2.3 6.2 21.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4228 PF14009.6 CDJ61197.1 - 2.3 8.6 9.4 2.5 8.5 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ureide_permease PF07168.11 CDJ61197.1 - 2.5 6.8 6.7 3.1 6.4 6.7 1.3 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 CDJ61197.1 - 2.7 7.4 18.2 3.2 7.2 18.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Ctr PF04145.15 CDJ61197.1 - 2.8 8.6 9.6 4.5 7.9 9.6 1.4 1 0 0 1 1 1 0 Ctr copper transporter family O-antigen_lig PF13425.6 CDJ61197.1 - 2.9 6.6 14.6 3.2 6.4 14.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Vfa1 PF08432.10 CDJ61197.1 - 3.2 8.0 29.1 3.7 7.8 29.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.11 CDJ61197.1 - 3.5 6.9 13.1 3.7 6.9 13.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PDDEXK_6 PF04720.12 CDJ61197.1 - 3.8 7.4 15.0 4.3 7.2 15.0 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Cellulose_synt PF03552.14 CDJ61197.1 - 4.9 5.5 9.1 4.7 5.6 9.1 1.1 1 0 0 1 1 1 0 Cellulose synthase LptF_LptG PF03739.14 CDJ61197.1 - 5.2 5.8 6.8 5.8 5.7 6.8 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF3306 PF11748.8 CDJ61197.1 - 7.5 7.4 20.4 14 6.6 20.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF789 PF05623.12 CDJ61197.1 - 7.6 6.1 16.7 10 5.7 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Paf1 PF03985.13 CDJ61197.1 - 8.5 5.2 30.7 13 4.6 30.7 1.2 1 0 0 1 1 1 0 Paf1 Med19 PF10278.9 CDJ61197.1 - 9 6.2 20.6 3.4 7.6 18.0 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CAF1 PF04857.20 CDJ61197.1 - 9.7 5.3 16.2 12 5.0 16.2 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Serinc PF03348.15 CDJ61198.1 - 1 8.2 21.5 0.47 9.3 1.2 3.5 3 0 0 3 3 3 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 CDJ61198.1 - 1.7 7.0 15.8 0.99 7.7 5.3 3.1 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 Ank_3 PF13606.6 CDJ61199.1 - 1.2e-14 52.9 0.5 1.3e-06 28.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 CDJ61199.1 - 2.7e-14 53.5 0.2 1.6e-11 44.7 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDJ61199.1 - 5.6e-14 52.3 0.4 2.5e-12 47.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CDJ61199.1 - 7.4e-14 51.5 1.5 7.9e-07 29.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CDJ61199.1 - 1.8e-13 50.4 0.1 6.6e-07 29.5 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) PAM2 PF07145.15 CDJ61201.1 - 0.052 13.3 0.4 0.62 9.9 0.2 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region AAA_18 PF13238.6 CDJ61202.1 - 3.3e-05 24.4 0.4 0.00031 21.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ61202.1 - 0.00068 20.1 0.0 0.0085 16.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ61202.1 - 0.0027 18.0 0.2 0.082 13.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CDJ61202.1 - 0.0039 17.4 4.4 0.041 14.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CDJ61202.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 CDJ61202.1 - 0.0096 16.0 0.3 0.52 10.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 CDJ61202.1 - 0.015 15.5 0.1 0.015 15.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDJ61202.1 - 0.019 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ61202.1 - 0.02 15.3 0.1 0.02 15.3 0.1 2.7 3 0 0 3 3 2 0 AAA ATPase domain DUF2075 PF09848.9 CDJ61202.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CDJ61202.1 - 0.025 13.9 0.2 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ADK PF00406.22 CDJ61202.1 - 0.026 14.6 0.0 32 4.6 0.0 3.4 3 0 0 3 3 3 0 Adenylate kinase ATPase PF06745.13 CDJ61202.1 - 0.038 13.4 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiC 6PF2K PF01591.18 CDJ61202.1 - 0.051 12.9 0.0 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Sulfotransfer_3 PF13469.6 CDJ61202.1 - 0.055 13.8 1.2 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase family Dpy-30 PF05186.13 CDJ61202.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif AAA_17 PF13207.6 CDJ61202.1 - 0.14 12.6 2.5 0.43 11.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDJ61202.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 CDJ61202.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Plasmodium_Vir PF05795.11 CDJ61202.1 - 0.87 8.9 20.0 0.028 13.8 10.6 2.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Cytidylate_kin PF02224.18 CDJ61202.1 - 0.94 9.2 0.0 0.94 9.2 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase BUD22 PF09073.10 CDJ61202.1 - 1.2 8.4 25.3 0.03 13.7 13.4 2.9 3 0 0 3 3 3 0 BUD22 SLC12 PF03522.15 CDJ61202.1 - 2.8 6.9 9.2 9 5.2 4.2 2.4 2 0 0 2 2 2 0 Solute carrier family 12 TFIIA PF03153.13 CDJ61202.1 - 4.6 7.1 29.0 0.24 11.3 1.9 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ61202.1 - 4.6 5.9 9.1 3.1 6.5 4.8 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4201 PF13870.6 CDJ61203.1 - 6.1e-11 42.4 14.0 6.1e-11 42.4 14.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) TFIIA PF03153.13 CDJ61203.1 - 0.073 13.1 28.1 0.036 14.1 26.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CDJ61203.1 - 0.65 10.1 15.5 5.4 7.2 0.9 3.3 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TMEM43 PF07787.12 CDJ61203.1 - 2.3 7.5 6.7 1.8 7.9 0.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 43 RNA_pol_Rpb2_6 PF00562.28 CDJ61204.1 - 3e-118 395.3 0.0 1.3e-117 393.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ61204.1 - 4.2e-42 144.0 0.0 6.2e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CDJ61204.1 - 6e-31 106.7 0.3 1.6e-30 105.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CDJ61204.1 - 7.7e-22 77.4 0.1 1.5e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 CDJ61204.1 - 1.3e-20 73.8 0.0 2.3e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CDJ61204.1 - 7e-20 71.0 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CDJ61204.1 - 6.5e-08 33.0 0.4 1.4e-07 31.9 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_PEP_C PF04513.12 CDJ61205.1 - 3.5e-05 23.9 1.6 0.00039 20.5 0.0 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.10 CDJ61205.1 - 0.0055 17.0 9.2 0.0055 17.0 9.2 3.6 2 1 1 3 3 3 1 HalX domain Goodbye PF17109.5 CDJ61205.1 - 0.045 14.2 0.0 0.045 14.2 0.0 2.7 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Apolipoprotein PF01442.18 CDJ61205.1 - 0.22 11.4 28.9 1.6 8.5 28.5 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.9 CDJ61205.1 - 0.23 11.8 17.1 3.1 8.1 2.2 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 CDJ61205.1 - 0.33 11.3 13.2 0.056 13.8 2.9 3.6 2 1 2 4 4 4 0 Uncharacterized KorC regulated protein A RIX1 PF08167.12 CDJ61205.1 - 0.54 10.0 3.3 2.2 8.0 0.6 2.3 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis TPR_MLP1_2 PF07926.12 CDJ61205.1 - 0.61 10.1 29.9 0.53 10.4 13.6 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 CDJ61205.1 - 0.95 10.0 17.3 0.27 11.7 5.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1798 PF08807.10 CDJ61205.1 - 1.1 9.4 9.2 0.12 12.5 2.4 2.3 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Mgr1 PF08602.10 CDJ61205.1 - 1.2 7.9 13.2 0.074 11.9 4.3 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DUF3584 PF12128.8 CDJ61205.1 - 1.2 6.5 25.6 6.6 4.1 25.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CCM2_C PF16545.5 CDJ61205.1 - 1.3 9.6 4.4 0.43 11.1 0.3 2.3 2 2 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology FlaC_arch PF05377.11 CDJ61205.1 - 1.6 9.2 11.5 3.1 8.2 0.2 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 CDJ61205.1 - 2.5 8.2 23.9 0.14 12.2 5.0 3.8 2 2 2 4 4 4 0 TolA binding protein trimerisation ApoO PF09769.9 CDJ61205.1 - 3.6 7.6 6.3 6.4 6.8 2.2 2.7 2 2 0 2 2 2 0 Apolipoprotein O DUF4407 PF14362.6 CDJ61205.1 - 4.1 6.7 18.5 4.1 6.7 15.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 CDJ61205.1 - 6.1 6.4 18.6 5.3 6.6 7.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cdh1_DBD_1 PF18196.1 CDJ61205.1 - 6.9 7.0 15.9 6.1 7.2 4.2 2.7 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 UPF0242 PF06785.11 CDJ61205.1 - 7.7 6.6 32.8 0.47 10.5 13.7 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 CDJ61205.1 - 8 4.3 11.5 1.3 6.9 2.9 2.1 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 CDJ61205.1 - 8.6 6.4 10.4 2.6 8.1 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nop14 PF04147.12 CDJ61206.1 - 1.7 6.7 10.0 2.5 6.2 10.0 1.2 1 0 0 1 1 1 0 Nop14-like family Coq4 PF05019.13 CDJ61207.1 - 5.7e-35 120.6 0.0 1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TFIIA PF03153.13 CDJ61207.1 - 1.6 8.7 7.5 2.2 8.2 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ61207.1 - 1.8 8.1 6.9 2.8 7.5 6.9 1.2 1 0 0 1 1 1 0 Spt20 family SF-assemblin PF06705.11 CDJ61208.1 - 6e-05 22.5 16.2 0.0003 20.2 15.4 2.2 1 1 1 2 2 2 1 SF-assemblin/beta giardin TPH PF13868.6 CDJ61208.1 - 0.019 13.5 34.8 0.022 13.3 34.8 1.0 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain SPOB_ab PF14682.6 CDJ61208.1 - 0.54 10.4 6.6 1.8 8.6 1.2 2.4 1 1 1 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Bestrophin PF01062.21 CDJ61208.1 - 0.55 9.6 5.4 0.64 9.4 5.4 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2428 PF10350.9 CDJ61210.1 - 8.8e-16 58.0 7.3 1.1e-12 47.8 3.7 4.8 4 1 0 4 4 4 2 Putative death-receptor fusion protein (DUF2428) DUF2992 PF11208.8 CDJ61210.1 - 5.5 7.3 9.4 1.4 9.2 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) RskA PF10099.9 CDJ61211.1 - 0.017 15.4 2.0 0.017 15.4 2.0 5.7 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Hamartin PF04388.12 CDJ61211.1 - 2.8 6.5 44.8 1.5 7.4 38.0 2.1 2 0 0 2 2 2 0 Hamartin protein Ephrin_rec_like PF07699.13 CDJ61213.1 - 1.2e-27 95.4 120.5 8e-07 28.7 0.2 12.9 12 3 2 14 14 14 8 Putative ephrin-receptor like Kringle PF00051.18 CDJ61213.1 - 1.8e-12 47.4 5.3 1e-11 45.0 5.3 2.4 1 0 0 1 1 1 1 Kringle domain Erg28 PF03694.13 CDJ61213.1 - 0.047 14.1 0.5 0.13 12.6 0.5 1.7 1 0 0 1 1 1 0 Erg28 like protein FRB_dom PF08771.11 CDJ61214.1 - 1.5e-11 44.6 0.0 1.5e-11 44.6 0.0 6.3 6 0 0 6 6 6 1 FKBP12-rapamycin binding domain CD99L2 PF12301.8 CDJ61214.1 - 0.023 15.0 6.7 0.038 14.3 2.1 2.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Spt20 PF12090.8 CDJ61215.1 - 0.007 16.0 14.9 0.007 16.0 14.9 4.1 2 1 2 4 4 4 1 Spt20 family Med15 PF09606.10 CDJ61215.1 - 0.29 9.8 115.6 0.36 9.5 115.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.9 CDJ61216.1 - 0.0048 17.2 14.8 0.0048 17.2 14.8 9.6 1 1 2 4 4 4 2 Anti-sigma-K factor rskA AP2 PF00847.20 CDJ61216.1 - 0.0054 16.9 1.3 0.0054 16.9 1.3 2.6 2 0 0 2 2 2 1 AP2 domain IBN_N PF03810.19 CDJ61218.1 - 1.4e-05 24.9 0.8 5.1e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2767 PF10965.8 CDJ61218.1 - 0.12 12.4 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) Peptidase_M99_m PF17130.4 CDJ61218.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 Ribosomal_L12 PF00542.19 CDJ61219.1 - 3.7e-19 68.8 2.5 3.7e-19 68.8 2.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDJ61219.1 - 2.6e-12 46.2 13.6 2.6e-12 46.2 13.6 2.6 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain FAD_binding_3 PF01494.19 CDJ61220.1 - 1.1e-41 143.3 1.8 4.3e-20 72.2 0.0 4.7 5 0 0 5 5 5 3 FAD binding domain Pyr_redox_3 PF13738.6 CDJ61220.1 - 0.00065 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDJ61220.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDJ61220.1 - 0.0043 17.3 0.2 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDJ61220.1 - 0.097 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDJ61220.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family SUV3_C PF12513.8 CDJ61221.1 - 2.5e-11 43.3 0.0 5.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CDJ61221.1 - 1.2e-05 25.7 0.0 0.00016 21.9 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 CDJ61221.1 - 0.0038 17.1 0.5 0.0094 15.8 0.5 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF2572 PF10833.8 CDJ61221.1 - 6.5 6.4 7.5 15 5.2 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Methyltr_RsmB-F PF01189.17 CDJ61224.1 - 2.7e-18 66.4 0.4 3.6e-10 39.8 0.0 2.7 2 1 1 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDJ61224.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF1084 PF06454.11 CDJ61227.1 - 2.1e-05 24.0 5.8 3.3e-05 23.4 4.4 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1084) Fuseless PF15993.5 CDJ61227.1 - 0.0006 19.1 1.0 0.00084 18.6 1.0 1.1 1 0 0 1 1 1 1 Fuseless Cadherin_C PF01049.17 CDJ61228.1 - 0.014 15.8 4.3 0.031 14.6 4.3 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region Carb_anhydrase PF00194.21 CDJ61230.1 - 5.7e-22 78.5 2.5 1.9e-13 50.6 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SMC_ScpB PF04079.16 CDJ61230.1 - 0.009 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB MFS_1 PF07690.16 CDJ61231.1 - 3.1e-10 39.5 17.3 2.5e-08 33.2 16.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MAP17 PF15807.5 CDJ61231.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Nop14 PF04147.12 CDJ61232.1 - 1.5 6.9 10.3 2.1 6.4 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 CDJ61232.1 - 2.6 7.8 6.9 4.4 7.1 6.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 CDJ61232.1 - 2.7 7.3 12.4 4.2 6.7 12.4 1.2 1 0 0 1 1 1 0 SDA1 DNA_ligase_aden PF01653.18 CDJ61233.1 - 7.4e-46 156.7 2.0 9.2e-12 44.7 0.0 6.6 6 1 1 7 7 7 6 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 CDJ61233.1 - 3.3e-23 81.4 0.0 6.8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain Radical_SAM PF04055.21 CDJ61234.1 - 1.2e-16 61.6 0.0 3.7e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 CDJ61234.1 - 7.6e-12 45.4 0.0 1.8e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation CMD PF02627.20 CDJ61234.1 - 0.01 15.9 0.2 0.029 14.4 0.2 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Vpu PF00558.19 CDJ61235.1 - 0.091 12.5 2.4 0.19 11.5 2.4 1.4 1 0 0 1 1 1 0 Vpu protein Cmyb_C PF09316.10 CDJ61235.1 - 0.72 9.5 5.7 2.5 7.8 5.5 2.0 1 1 0 1 1 1 0 C-myb, C-terminal CASP_C PF08172.12 CDJ61235.1 - 5.8 6.2 11.3 0.91 8.8 4.3 2.3 2 0 0 2 2 2 0 CASP C terminal Ocnus PF05005.15 CDJ61236.1 - 3.7e-22 78.5 0.2 5.9e-22 77.8 0.2 1.2 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) MukB_hinge PF16330.5 CDJ61236.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 MukB hinge domain E1_dh PF00676.20 CDJ61237.1 - 1.3e-82 277.1 0.0 1.6e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CDJ61237.1 - 2.9e-11 43.4 0.7 6.6e-11 42.2 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CDJ61237.1 - 4.2e-05 22.9 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CDJ61237.1 - 0.00016 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain PP2C_C PF07830.13 CDJ61238.1 - 0.0071 16.8 0.2 0.0071 16.8 0.2 3.7 4 0 0 4 4 4 1 Protein serine/threonine phosphatase 2C, C-terminal domain Ntox28 PF15605.6 CDJ61238.1 - 0.11 12.8 16.4 0.71 10.1 2.5 3.6 3 1 1 4 4 4 0 Bacterial toxin 28 Nexin_C PF08628.12 CDJ61239.1 - 0.11 13.1 0.4 0.54 10.9 0.0 2.4 3 0 0 3 3 3 0 Sorting nexin C terminal IL32 PF15225.6 CDJ61240.1 - 0.034 14.5 3.0 0.13 12.6 0.0 3.3 3 0 0 3 3 3 0 Interleukin 32 Histone PF00125.24 CDJ61241.1 - 6.2e-53 178.6 1.5 6.9e-53 178.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDJ61241.1 - 9e-05 22.8 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CDJ61241.1 - 0.00014 22.4 0.9 0.00017 22.2 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CDJ61241.1 - 0.00038 20.5 0.1 0.00071 19.7 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CDJ61241.1 - 0.0094 16.0 0.1 0.015 15.3 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CDJ61241.1 - 0.015 15.6 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDEase_I PF00233.19 CDJ61242.1 - 3.4e-57 193.9 1.3 3.4e-57 193.9 1.3 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase NFACT-R_1 PF05670.13 CDJ61243.1 - 1.1e-37 129.0 0.0 2.4e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF1943 PF09172.11 CDJ61243.1 - 0.29 10.3 9.8 0.42 9.8 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Tho2 PF11262.8 CDJ61243.1 - 8.3 5.5 12.5 14 4.7 12.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nnf1 PF03980.14 CDJ61247.1 - 0.00063 20.1 6.5 0.14 12.6 2.0 2.7 2 1 0 2 2 2 2 Nnf1 TRAPPC-Trs85 PF12739.7 CDJ61247.1 - 0.041 12.9 1.3 0.057 12.4 1.3 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RP-C_C PF11800.8 CDJ61247.1 - 0.063 13.4 4.2 0.11 12.6 4.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_60s PF00428.19 CDJ61247.1 - 2.3 8.9 6.4 1.4 9.5 3.6 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Presenilin PF01080.17 CDJ61247.1 - 7 5.3 5.7 8.1 5.1 5.7 1.2 1 0 0 1 1 1 0 Presenilin Sox_N PF12444.8 CDJ61247.1 - 7.3 7.8 12.5 23 6.2 12.5 1.8 1 0 0 1 1 1 0 Sox developmental protein N terminal ABC_tran_CTD PF16326.5 CDJ61247.1 - 9.6 6.5 15.0 0.066 13.5 3.1 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain HA2 PF04408.23 CDJ61248.1 - 0.016 15.5 0.6 0.027 14.8 0.6 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) sCache_like PF16736.5 CDJ61248.1 - 0.02 15.0 4.1 0.028 14.5 4.1 1.1 1 0 0 1 1 1 0 Single Cache-like SUIM_assoc PF16619.5 CDJ61248.1 - 0.029 14.4 3.9 0.029 14.4 3.9 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Laps PF10169.9 CDJ61248.1 - 0.075 13.6 3.9 0.1 13.2 3.9 1.1 1 0 0 1 1 1 0 Learning-associated protein Malic_M PF03949.15 CDJ61248.1 - 0.11 11.8 1.2 0.13 11.5 1.2 1.1 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain TFIIA PF03153.13 CDJ61248.1 - 0.13 12.3 15.6 0.15 12.0 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ubiquitin PF00240.23 CDJ61248.1 - 1.3 8.8 7.9 2.1 8.1 0.0 3.0 1 1 2 3 3 3 0 Ubiquitin family Presenilin PF01080.17 CDJ61248.1 - 5.1 5.8 5.4 6 5.5 5.4 1.1 1 0 0 1 1 1 0 Presenilin AF-4 PF05110.13 CDJ61249.1 - 0.00096 17.4 29.4 0.00096 17.4 29.4 3.3 3 0 0 3 3 3 2 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 CDJ61249.1 - 0.015 15.8 18.8 0.015 15.8 18.8 5.7 5 1 0 5 5 5 0 Secretin N-terminal domain PmbA_TldD PF01523.16 CDJ61249.1 - 0.97 9.2 10.2 0.23 11.3 4.0 2.4 2 0 0 2 2 2 0 Putative modulator of DNA gyrase JAB PF01398.21 CDJ61250.1 - 4.2e-32 110.6 0.1 5.5e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDJ61250.1 - 3e-09 36.7 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FH2 PF02181.23 CDJ61251.1 - 0.091 11.9 0.0 0.091 11.9 0.0 3.0 3 0 0 3 3 3 0 Formin Homology 2 Domain PKcGMP_CC PF16808.5 CDJ61251.1 - 0.41 10.6 2.2 9 6.2 0.1 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NPV_P10 PF05531.12 CDJ61251.1 - 9.5 6.8 10.0 2.5 8.6 1.7 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PTPA PF03095.15 CDJ61252.1 - 4.4e-28 98.6 0.0 4.8e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MIP PF00230.20 CDJ61254.1 - 9.1e-12 45.2 29.9 2.1e-07 30.9 13.4 4.4 2 2 2 4 4 4 4 Major intrinsic protein AAA PF00004.29 CDJ61255.1 - 1.9e-43 148.0 0.0 3.4e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ61255.1 - 2.3e-11 43.3 0.6 4.6e-11 42.3 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDJ61255.1 - 4.3e-07 30.3 0.0 0.00091 19.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDJ61255.1 - 8.7e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDJ61255.1 - 7.3e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDJ61255.1 - 2e-05 25.1 0.2 0.002 18.6 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CDJ61255.1 - 2.5e-05 24.3 0.2 0.00017 21.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CDJ61255.1 - 3.5e-05 23.1 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDJ61255.1 - 0.0006 19.6 0.1 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 CDJ61255.1 - 0.00093 19.8 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDJ61255.1 - 0.001 19.2 0.0 0.0067 16.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CDJ61255.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CDJ61255.1 - 0.002 17.4 0.0 0.0042 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CDJ61255.1 - 0.0025 18.1 0.2 0.0067 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ61255.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDJ61255.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CDJ61255.1 - 0.0079 15.8 0.4 0.15 11.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 CDJ61255.1 - 0.0093 15.8 0.2 0.041 13.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDJ61255.1 - 0.013 15.2 0.9 0.028 14.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ61255.1 - 0.021 14.6 0.2 0.12 12.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CDJ61255.1 - 0.021 14.7 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 CDJ61255.1 - 0.021 14.3 0.0 0.064 12.8 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CDJ61255.1 - 0.022 14.1 0.2 0.52 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 CDJ61255.1 - 0.023 14.1 0.2 0.069 12.6 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 CDJ61255.1 - 0.029 14.3 0.1 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CDJ61255.1 - 0.046 14.1 0.3 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDJ61255.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDJ61255.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CDJ61255.1 - 0.083 12.6 0.0 0.43 10.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Nuc_deoxyrib_tr PF05014.15 CDJ61255.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase NB-ARC PF00931.22 CDJ61255.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CDJ61255.1 - 0.12 12.9 0.1 0.25 11.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter DUF1128 PF06569.11 CDJ61255.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) NTPase_1 PF03266.15 CDJ61255.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.6 1 1 0 1 1 1 0 NTPase DnaJ_C PF01556.18 CDJ61257.1 - 0.00027 21.1 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain AAA PF00004.29 CDJ61259.1 - 7.3e-83 275.6 0.0 5.8e-41 140.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ61259.1 - 7.7e-19 67.2 1.1 1e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CDJ61259.1 - 2.5e-12 46.8 0.0 3.8e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDJ61259.1 - 1.1e-10 41.8 0.0 0.00057 20.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CDJ61259.1 - 1.4e-10 41.6 0.0 0.0001 22.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDJ61259.1 - 1.6e-09 38.4 1.4 0.00021 21.7 0.2 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CDJ61259.1 - 9e-09 35.5 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ61259.1 - 2e-08 34.4 0.3 0.021 14.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 CDJ61259.1 - 7.3e-07 29.2 0.7 0.0036 17.2 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein TsaE PF02367.17 CDJ61259.1 - 1e-05 25.6 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 CDJ61259.1 - 1.5e-05 25.2 0.0 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.6 CDJ61259.1 - 1.9e-05 24.9 3.6 0.053 13.8 0.0 4.3 3 2 2 5 5 5 1 AAA domain TIP49 PF06068.13 CDJ61259.1 - 4.5e-05 22.8 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 CDJ61259.1 - 5.5e-05 23.5 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CDJ61259.1 - 6.4e-05 22.9 0.7 0.33 10.8 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 CDJ61259.1 - 9.7e-05 22.9 0.0 0.099 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ61259.1 - 0.00011 22.0 0.1 0.089 12.5 0.0 2.8 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 CDJ61259.1 - 0.00013 22.3 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ61259.1 - 0.00035 20.4 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CDJ61259.1 - 0.00084 18.8 1.1 0.041 13.3 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 CDJ61259.1 - 0.0011 18.9 0.0 0.2 11.7 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 CDJ61259.1 - 0.0016 18.0 0.1 0.11 12.0 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDJ61259.1 - 0.0017 18.1 0.1 2.6 7.7 0.0 3.5 2 2 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 CDJ61259.1 - 0.0024 18.4 0.1 0.11 13.0 0.0 2.6 2 1 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 CDJ61259.1 - 0.0027 17.0 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.11 CDJ61259.1 - 0.0027 17.5 0.0 2.4 8.0 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CDJ61259.1 - 0.0052 17.2 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CDJ61259.1 - 0.006 15.8 0.0 0.54 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CDJ61259.1 - 0.012 15.5 0.2 1.6 8.6 0.0 3.2 3 1 0 3 3 3 0 NTPase PhoH PF02562.16 CDJ61259.1 - 0.026 14.0 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 CDJ61259.1 - 0.047 13.4 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDJ61259.1 - 0.047 13.6 0.1 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CDJ61259.1 - 0.052 12.9 0.4 1.4 8.2 0.0 2.8 2 1 0 2 2 2 0 KaiC DUF2075 PF09848.9 CDJ61259.1 - 0.056 12.7 0.0 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 CDJ61259.1 - 0.08 12.2 0.0 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 CDJ61259.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CDJ61259.1 - 0.12 12.0 0.3 2.2 7.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain CAF1 PF04857.20 CDJ61261.1 - 4.6e-25 88.4 0.5 1.4e-13 50.7 0.0 3.2 2 1 1 3 3 3 2 CAF1 family ribonuclease SUIM_assoc PF16619.5 CDJ61261.1 - 5.4e-07 29.6 8.9 4.3e-05 23.5 0.8 3.8 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ61261.1 - 0.00087 19.0 17.5 0.0014 18.3 17.5 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 CDJ61261.1 - 0.015 15.3 14.5 0.021 14.8 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CDJ61261.1 - 0.06 12.3 2.0 0.076 12.0 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 CDJ61261.1 - 0.37 9.7 15.8 0.63 8.9 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 CDJ61261.1 - 1.2 9.0 4.6 2.3 8.1 4.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 CDJ61261.1 - 2.1 6.9 28.9 3.6 6.1 28.9 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.13 CDJ61261.1 - 6.5 7.4 10.3 12 6.6 10.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MutS_II PF05188.17 CDJ61262.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 MutS domain II Arm PF00514.23 CDJ61264.1 - 5.7e-17 61.1 0.4 0.00061 19.7 0.0 4.4 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CDJ61264.1 - 0.0021 17.6 0.1 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CDJ61264.1 - 0.0032 17.8 1.0 0.096 13.1 0.2 2.9 1 1 1 3 3 3 2 HEAT repeats WAPL PF07814.13 CDJ61264.1 - 0.17 10.6 0.0 1 8.1 0.0 2.3 3 0 0 3 3 3 0 Wings apart-like protein regulation of heterochromatin DSPc PF00782.20 CDJ61265.1 - 4.2e-05 23.4 0.2 4.2e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDJ61265.1 - 0.0048 16.9 0.1 0.0048 16.9 0.1 3.3 4 0 0 4 4 4 1 Tyrosine phosphatase family ACDC PF14733.6 CDJ61266.1 - 1.4e-16 60.6 0.0 6.7e-16 58.4 0.0 2.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ61266.1 - 2.1e-05 24.6 2.9 0.00014 22.0 2.9 2.5 1 0 0 1 1 1 1 AP2 domain CT_A_B PF02626.15 CDJ61268.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B RRM_1 PF00076.22 CDJ61269.1 - 8.7e-22 76.7 0.0 3.7e-08 33.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDJ61269.1 - 0.0007 19.4 0.0 8.7 6.3 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif VWA_3 PF13768.6 CDJ61269.1 - 0.1 12.5 0.3 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Ribonuc_red_sm PF00268.21 CDJ61270.1 - 3.2e-101 338.5 1.3 4.6e-101 338.0 1.3 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain BROMI PF14961.6 CDJ61270.1 - 0.031 11.7 0.1 0.041 11.3 0.1 1.1 1 0 0 1 1 1 0 Broad-minded protein cobW PF02492.19 CDJ61271.1 - 4.4e-24 85.0 0.1 1.5e-23 83.2 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Dishevelled PF02377.15 CDJ61271.1 - 0.0031 18.0 3.1 0.0031 18.0 3.1 2.2 2 1 0 2 2 1 1 Dishevelled specific domain Consortin_C PF15281.6 CDJ61271.1 - 0.0064 16.5 1.7 0.13 12.3 0.7 2.5 2 0 0 2 2 2 1 Consortin C-terminus Velvet PF11754.8 CDJ61271.1 - 0.027 14.4 12.8 0.75 9.7 6.0 2.2 2 0 0 2 2 2 0 Velvet factor SpoIIP PF07454.11 CDJ61271.1 - 0.037 13.5 10.2 0.033 13.7 7.3 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 CDJ61271.1 - 0.07 12.3 4.4 0.033 13.4 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) XRN_N PF03159.18 CDJ61271.1 - 0.11 12.0 13.1 0.19 11.1 7.4 2.4 2 1 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Zip PF02535.22 CDJ61271.1 - 0.12 11.5 2.0 0.28 10.3 0.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 CDJ61271.1 - 0.2 10.4 14.3 0.04 12.7 7.4 2.1 2 0 0 2 2 2 0 Presenilin ATAD4 PF15321.6 CDJ61271.1 - 0.31 12.4 8.9 1 10.8 2.8 2.7 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF4770 PF15994.5 CDJ61271.1 - 0.38 11.0 13.6 0.23 11.7 8.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CDJ61271.1 - 0.39 10.4 7.6 0.51 10.0 5.5 2.0 2 0 0 2 2 2 0 Connexin FAM60A PF15396.6 CDJ61271.1 - 0.46 10.5 7.1 0.33 10.9 3.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF2828 PF11443.8 CDJ61271.1 - 0.54 8.3 9.7 0.17 9.9 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) EPL1 PF10513.9 CDJ61271.1 - 0.56 10.6 13.6 0.36 11.2 7.7 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like SLC12 PF03522.15 CDJ61271.1 - 0.82 8.6 12.4 0.35 9.8 8.1 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CDJ61271.1 - 0.87 9.6 11.1 2.4 8.2 5.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 CDJ61271.1 - 0.89 7.4 11.3 0.29 9.0 7.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4050 PF13259.6 CDJ61271.1 - 1.1 9.6 10.3 1.7 8.9 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Band_3_cyto PF07565.13 CDJ61271.1 - 1.2 8.9 11.4 1.4 8.6 6.7 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Apc15p PF05841.11 CDJ61271.1 - 1.8 9.4 23.4 0.043 14.6 12.4 2.8 3 0 0 3 3 2 0 Apc15p protein DUF913 PF06025.12 CDJ61271.1 - 2.2 7.2 8.0 0.6 9.0 3.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2370 PF10176.9 CDJ61271.1 - 2.2 7.9 4.6 0.91 9.1 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) FAM176 PF14851.6 CDJ61271.1 - 2.7 7.6 9.2 2.6 7.7 6.6 2.3 2 0 0 2 2 2 0 FAM176 family Ureide_permease PF07168.11 CDJ61271.1 - 3.3 6.4 6.4 11 4.6 6.4 1.8 1 0 0 1 1 1 0 Ureide permease RR_TM4-6 PF06459.12 CDJ61271.1 - 4.1 7.2 15.4 3.8 7.3 10.8 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MecA PF05389.12 CDJ61271.1 - 4.3 6.9 12.7 0.73 9.4 6.2 2.5 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) Afi1 PF07792.12 CDJ61271.1 - 4.3 7.8 13.7 6.5 7.2 10.7 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Plasmodium_Vir PF05795.11 CDJ61271.1 - 6.3 6.1 9.3 0.55 9.6 3.4 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein XRN_M PF17846.1 CDJ61271.1 - 6.5 5.6 7.6 1.3 7.9 3.4 1.8 2 0 0 2 2 2 0 Xrn1 helical domain MDM10 PF12519.8 CDJ61271.1 - 6.9 5.4 9.7 1 8.1 4.9 1.8 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 OATP PF03137.20 CDJ61271.1 - 8.3 4.6 10.7 0.58 8.4 3.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S64 PF08192.11 CDJ61271.1 - 8.3 4.8 11.5 0.73 8.3 5.6 2.0 2 0 0 2 2 2 0 Peptidase family S64 DNApol_Exo PF18136.1 CDJ61271.1 - 8.7 5.4 15.1 14 4.7 0.1 2.2 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain TPR_1 PF00515.28 CDJ61272.1 - 1.4e-16 59.5 11.7 2.3e-06 27.1 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDJ61272.1 - 3.3e-16 58.0 12.6 1.9e-05 24.4 0.3 6.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDJ61272.1 - 1.4e-11 43.9 5.9 6.7e-06 25.7 0.7 5.6 3 2 3 6 6 6 2 TPR repeat TPR_19 PF14559.6 CDJ61272.1 - 1e-08 35.5 1.3 8.7e-05 23.0 0.9 5.6 5 1 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ61272.1 - 1.1e-08 35.6 1.3 2.9e-06 27.8 2.7 6.9 5 2 0 6 6 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDJ61272.1 - 1.2e-08 34.9 0.8 3e-05 24.1 0.3 3.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ61272.1 - 4.1e-08 32.8 6.1 0.0011 19.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ61272.1 - 1.5e-07 31.6 9.1 0.0018 18.5 2.7 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ61272.1 - 2.9e-06 26.9 2.4 0.068 13.2 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDJ61272.1 - 6.2e-06 26.2 19.0 0.0088 16.4 0.3 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDJ61272.1 - 7.8e-05 22.8 4.3 0.32 11.2 0.0 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CDJ61272.1 - 0.0036 18.0 0.1 0.2 12.6 0.0 8.5 6 2 3 9 9 7 3 Tetratricopeptide repeat DUF3506 PF12014.8 CDJ61272.1 - 0.5 10.4 9.1 0.067 13.2 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) MMR1 PF08505.10 CDJ61273.1 - 0.00022 21.6 7.6 0.00022 21.6 7.6 4.3 4 1 0 4 4 4 1 Mitochondrial Myo2 receptor-related protein Sporozoite_P67 PF05642.11 CDJ61276.1 - 3.9e-07 28.6 0.4 3.9e-07 28.6 0.4 6.7 4 2 3 7 7 7 2 Sporozoite P67 surface antigen RRM_1 PF00076.22 CDJ61276.1 - 0.00013 21.7 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ61276.1 - 0.00079 19.8 5.0 0.00079 19.8 5.0 14.3 3 1 6 10 10 10 2 Anti-sigma-K factor rskA RskA PF10099.9 CDJ61277.1 - 0.017 15.5 0.9 0.017 15.5 0.9 12.5 2 2 6 9 9 9 0 Anti-sigma-K factor rskA Notch PF00066.17 CDJ61279.1 - 1.6e-44 150.1 103.3 6e-09 36.2 11.7 6.2 6 0 0 6 6 6 6 LNR domain DUF4949 PF16307.5 CDJ61279.1 - 0.017 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) PDE8 PF08629.10 CDJ61281.1 - 0.16 12.0 0.6 0.46 10.5 0.6 1.8 1 0 0 1 1 1 0 PDE8 phosphodiesterase Fasciclin PF02469.22 CDJ61282.1 - 3e-07 30.7 0.0 6.7e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Ribosomal_L13e PF01294.18 CDJ61283.1 - 0.068 13.0 0.9 0.1 12.4 0.9 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e Radial_spoke_3 PF06098.11 CDJ61284.1 - 2.3e-38 132.1 25.9 4.5e-37 127.9 25.9 2.4 1 1 0 1 1 1 1 Radial spoke protein 3 DUF2722 PF10846.8 CDJ61284.1 - 0.0005 19.1 8.9 0.00056 19.0 8.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ61284.1 - 0.012 15.2 20.5 0.024 14.2 20.5 1.6 1 0 0 1 1 1 0 Spt20 family MAJIN PF15077.6 CDJ61284.1 - 0.2 11.4 9.4 0.37 10.5 9.4 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Ndc1_Nup PF09531.10 CDJ61284.1 - 0.22 10.2 9.3 0.26 9.9 9.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 CDJ61284.1 - 0.4 9.6 7.9 0.62 9.0 7.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Miga PF10265.9 CDJ61284.1 - 1.3 7.9 10.1 2 7.3 10.1 1.2 1 0 0 1 1 1 0 Mitoguardin Neur_chan_memb PF02932.16 CDJ61284.1 - 1.4 8.9 5.9 2 8.4 5.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 CDJ61284.1 - 2 5.4 14.5 2.4 5.2 14.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CDJ61284.1 - 3.7 6.2 10.1 4.9 5.8 10.1 1.2 1 0 0 1 1 1 0 Presenilin DUF2149 PF09919.9 CDJ61284.1 - 4.1 7.7 7.9 19 5.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Asp PF00026.23 CDJ61285.1 - 4.8e-15 55.8 6.2 4.4e-07 29.6 0.0 3.7 2 1 1 4 4 4 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDJ61285.1 - 1e-11 45.4 10.9 3e-11 43.9 0.2 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal DUF5531 PF17671.1 CDJ61285.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5531) DUF1180 PF06679.12 CDJ61285.1 - 0.014 15.8 7.5 0.014 15.8 7.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2615 PF11027.8 CDJ61285.1 - 0.089 12.9 0.1 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Pex14_N PF04695.13 CDJ61285.1 - 0.12 13.0 13.8 0.55 10.9 7.7 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 CDJ61285.1 - 0.23 11.3 2.9 0.28 11.0 2.9 1.4 1 1 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDJ61285.1 - 0.36 9.5 3.3 0.68 8.5 3.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GRP PF07172.11 CDJ61285.1 - 3.8 8.3 15.1 3.5e+03 -1.3 15.1 2.4 1 1 0 1 1 1 0 Glycine rich protein family Macoilin PF09726.9 CDJ61285.1 - 4.8 5.6 8.0 6.7 5.1 8.0 1.1 1 0 0 1 1 1 0 Macoilin family TPR_14 PF13428.6 CDJ61286.1 - 2.5e-05 24.7 23.8 0.027 15.3 2.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDJ61286.1 - 0.01 16.1 17.4 0.54 10.6 0.6 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat FAM176 PF14851.6 CDJ61286.1 - 0.015 15.0 25.9 0.039 13.6 7.0 3.6 3 0 0 3 3 3 0 FAM176 family DUF913 PF06025.12 CDJ61286.1 - 0.037 13.0 21.8 0.047 12.7 5.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) SPX PF03105.19 CDJ61286.1 - 0.29 11.0 32.4 0.11 12.4 21.6 2.9 3 0 0 3 3 3 0 SPX domain TPR_10 PF13374.6 CDJ61286.1 - 1.1 9.2 8.4 18 5.4 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C37 PF05416.12 CDJ61286.1 - 2.7 6.4 7.3 4.8 5.6 7.3 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Connexin PF00029.19 CDJ61286.1 - 4.4 7.0 17.9 0.076 12.8 4.6 3.1 3 0 0 3 3 3 0 Connexin Cyclin_N PF00134.23 CDJ61287.1 - 2.3e-12 46.8 0.8 5.6e-12 45.5 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDJ61287.1 - 0.00012 22.1 0.0 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DDE_Tnp_1_2 PF13586.6 CDJ61288.1 - 0.31 11.5 2.3 1 9.8 2.3 1.9 1 0 0 1 1 1 0 Transposase DDE domain Ribosomal_S8e PF01201.22 CDJ61290.1 - 7.9e-48 162.1 10.9 1.7e-47 161.0 10.9 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e CCDC-167 PF15188.6 CDJ61290.1 - 1.8 9.0 8.8 4.9 7.6 5.4 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.25 CDJ61291.1 - 3.3e-60 203.7 0.0 3.8e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61291.1 - 5.3e-37 127.5 0.0 6.3e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ61291.1 - 6.2e-06 26.3 0.0 0.011 15.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDJ61291.1 - 0.00018 20.5 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDJ61291.1 - 0.00032 20.1 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDJ61291.1 - 0.016 14.6 0.2 0.03 13.7 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bax1-I PF01027.20 CDJ61296.1 - 0.00015 21.7 0.3 0.00016 21.6 0.3 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cpn60_TCP1 PF00118.24 CDJ61297.1 - 2e-127 425.8 6.2 2.2e-95 320.1 0.8 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Na_K-ATPase PF00287.18 CDJ61298.1 - 0.041 13.1 0.9 0.064 12.4 0.9 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain PAP2 PF01569.21 CDJ61298.1 - 1.8 8.4 9.9 11 5.8 0.4 3.5 3 0 0 3 3 3 0 PAP2 superfamily SLC12 PF03522.15 CDJ61298.1 - 4 6.4 11.2 9.5 5.1 11.2 1.7 1 0 0 1 1 1 0 Solute carrier family 12 Couple_hipA PF13657.6 CDJ61299.1 - 0.079 13.6 0.4 0.24 12.1 0.1 2.0 2 0 0 2 2 2 0 HipA N-terminal domain Phage_TAC_7 PF10109.9 CDJ61300.1 - 0.22 11.7 3.0 0.43 10.7 0.0 3.1 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 RabGAP-TBC PF00566.18 CDJ61303.1 - 2.7e-32 112.2 0.7 2.3e-17 63.4 0.0 2.8 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Peptidase_C48 PF02902.19 CDJ61304.1 - 0.0027 17.6 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Myb_DNA-binding PF00249.31 CDJ61305.1 - 1.2e-10 41.4 0.8 2.3e-10 40.5 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDJ61305.1 - 1.4e-07 31.7 0.3 4.8e-07 29.9 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIIA PF03153.13 CDJ61305.1 - 2.8 7.8 31.7 0.11 12.5 23.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNase_H2_suC PF08615.11 CDJ61306.1 - 2.8e-10 40.5 0.0 5.4e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) UPF0016 PF01169.19 CDJ61307.1 - 3.1e-32 110.7 15.8 1.7e-16 60.3 3.0 3.3 2 1 0 2 2 2 2 Uncharacterized protein family UPF0016 MFS_1 PF07690.16 CDJ61310.1 - 0.057 12.3 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Major Facilitator Superfamily Oxidored_q6 PF01058.22 CDJ61311.1 - 0.1 12.4 0.1 0.34 10.7 0.1 1.9 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Sel1 PF08238.12 CDJ61315.1 - 1.7e-29 101.6 14.5 0.00048 20.7 0.2 10.6 10 0 0 10 10 10 7 Sel1 repeat Mucin PF01456.17 CDJ61315.1 - 0.0037 17.3 10.9 0.0037 17.3 10.9 4.0 2 1 0 3 3 3 1 Mucin-like glycoprotein MSP1a PF11670.8 CDJ61315.1 - 2.6 7.3 13.6 0.11 11.8 1.3 3.1 2 1 0 2 2 2 0 Major surface protein 1a (MSP1a) Exo_endo_phos PF03372.23 CDJ61316.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C1 PF00112.23 CDJ61317.1 - 8.6e-47 160.0 0.0 1.4e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDJ61317.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C1-like family PAP_assoc PF03828.19 CDJ61319.1 - 1.9e-05 24.8 0.0 9e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase RskA PF10099.9 CDJ61319.1 - 0.00087 19.6 3.1 0.00087 19.6 3.1 4.8 4 1 1 5 5 5 1 Anti-sigma-K factor rskA NTP_transf_2 PF01909.23 CDJ61319.1 - 0.0059 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1676 PF07898.13 CDJ61319.1 - 1 9.4 0.0 1 9.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) SNF2_N PF00176.23 CDJ61320.1 - 3.5e-44 151.0 0.1 6.1e-44 150.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ61320.1 - 1.7e-15 57.3 0.0 8.2e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ61320.1 - 4.9e-06 26.6 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CDJ61320.1 - 0.0037 17.3 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 CDJ61321.1 - 0.039 13.8 1.3 0.093 12.6 1.4 1.9 1 1 0 1 1 1 0 BAH domain SET PF00856.28 CDJ61322.1 - 8e-16 58.9 2.9 5.8e-14 52.8 0.0 3.6 3 0 0 3 3 3 2 SET domain Gp-FAR-1 PF05823.12 CDJ61322.1 - 0.29 11.5 9.5 0.21 12.0 4.4 3.0 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Arm PF00514.23 CDJ61323.1 - 1.3e-08 34.6 5.2 0.061 13.4 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CDJ61323.1 - 3.1e-06 27.3 0.0 4.2e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 CDJ61323.1 - 5.7e-05 23.4 0.2 0.032 14.6 0.0 3.7 2 1 2 4 4 4 1 HEAT repeats Proteasom_PSMB PF10508.9 CDJ61323.1 - 0.45 9.0 2.1 3.2 6.2 2.1 2.0 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 CDJ61323.1 - 1 9.8 9.1 43 4.8 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat Tim17 PF02466.19 CDJ61325.1 - 5.5e-23 81.5 7.0 8.8e-23 80.8 7.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0060 PF02694.15 CDJ61325.1 - 0.11 12.8 0.8 0.15 12.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3128 PF11326.8 CDJ61326.1 - 0.049 14.0 1.2 0.11 12.9 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Antistasin PF02822.14 CDJ61328.1 - 0.27 11.9 4.9 6.7 7.4 0.7 3.4 2 0 0 2 2 2 0 Antistasin family PDR_CDR PF06422.12 CDJ61329.1 - 0.096 12.6 0.2 0.43 10.5 0.2 2.2 1 0 0 1 1 1 0 CDR ABC transporter DHO_dh PF01180.21 CDJ61330.1 - 5.9e-103 344.1 0.0 7.6e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDJ61330.1 - 0.0042 16.2 0.1 0.011 14.8 0.1 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase RecX PF02631.16 CDJ61330.1 - 0.079 13.4 0.3 0.37 11.3 0.9 1.8 2 0 0 2 2 2 0 RecX family FAM92 PF06730.11 CDJ61330.1 - 0.092 12.2 0.3 0.15 11.5 0.3 1.2 1 0 0 1 1 1 0 FAM92 protein CarD_CdnL_TRCF PF02559.16 CDJ61330.1 - 0.19 12.5 0.4 0.46 11.2 0.2 1.7 2 0 0 2 2 2 0 CarD-like/TRCF domain UvrD-helicase PF00580.21 CDJ61331.1 - 4.1e-45 154.6 0.0 2.1e-44 152.3 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CDJ61331.1 - 3.9e-28 98.8 0.0 2.7e-18 66.5 0.0 3.6 4 0 0 4 4 4 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDJ61331.1 - 7.5e-19 68.5 0.0 2.9e-18 66.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDJ61331.1 - 2.1e-10 40.3 0.7 0.00024 20.8 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 CDJ61331.1 - 0.028 14.0 0.0 0.028 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDJ61331.1 - 0.04 13.6 0.0 0.04 13.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain TTL PF03133.15 CDJ61335.1 - 4e-27 95.1 33.8 1.8e-16 60.1 1.2 3.3 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDJ61335.1 - 4.2e-05 22.9 0.0 4.2e-05 22.9 0.0 3.5 3 1 0 3 3 3 1 YheC/D like ATP-grasp Pox_Ag35 PF03286.14 CDJ61335.1 - 0.00062 19.6 6.3 0.00062 19.6 6.3 2.9 3 0 0 3 3 3 1 Pox virus Ag35 surface protein DUF1754 PF08555.10 CDJ61335.1 - 0.0038 18.0 11.3 0.0038 18.0 11.3 4.3 4 1 0 4 4 4 1 Eukaryotic family of unknown function (DUF1754) CCDC53 PF10152.9 CDJ61335.1 - 1.6 9.1 37.1 0.47 10.9 1.4 3.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Vfa1 PF08432.10 CDJ61335.1 - 5.3 7.3 46.1 1.2 9.5 11.6 3.8 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 CDJ61335.1 - 5.5 7.0 29.2 5.6 7.0 1.7 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 CDJ61335.1 - 7.4 4.9 26.3 1.7 7.0 21.2 1.9 2 0 0 2 2 2 0 Peptidase family S64 Tim54 PF11711.8 CDJ61335.1 - 8.4 5.1 35.0 0.035 12.9 3.2 3.4 4 0 0 4 4 4 0 Inner membrane protein import complex subunit Tim54 DAG_kinase_N PF14513.6 CDJ61335.1 - 9.9 6.3 30.9 1.9 8.7 2.5 3.2 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus Pyridoxal_deC PF00282.19 CDJ61336.1 - 0.02 13.6 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Roughex PF06020.11 CDJ61336.1 - 0.03 13.4 1.6 0.029 13.5 1.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Inj_translocase PF16928.5 CDJ61336.1 - 0.058 12.8 4.5 0.075 12.5 4.5 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Spt20 PF12090.8 CDJ61336.1 - 0.16 11.6 7.8 0.17 11.5 7.8 1.1 1 0 0 1 1 1 0 Spt20 family RNase_P_p30 PF01876.16 CDJ61337.1 - 9.7e-19 67.7 0.1 5.8e-15 55.4 0.4 3.7 3 1 0 3 3 3 1 RNase P subunit p30 DUF2722 PF10846.8 CDJ61337.1 - 0.041 12.8 3.5 0.059 12.3 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CDJ61337.1 - 0.094 12.8 9.7 4.1 7.5 10.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CDJ61337.1 - 0.92 9.1 14.6 1.6 8.3 14.6 1.3 1 0 0 1 1 1 0 Spt20 family Helicase_C PF00271.31 CDJ61338.1 - 1.3e-18 67.3 0.1 1.7e-15 57.3 0.0 3.2 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ61338.1 - 1.6e-13 50.8 17.3 4e-13 49.5 10.9 3.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CDJ61338.1 - 1.1e-11 44.8 0.1 4.2e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ETRAMP PF09716.10 CDJ61338.1 - 0.03 14.4 0.1 0.03 14.4 0.1 3.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF572 PF04502.13 CDJ61339.1 - 0.02 14.5 22.0 0.032 13.9 22.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.13 CDJ61339.1 - 0.097 11.2 27.1 0.13 10.8 27.1 1.1 1 0 0 1 1 1 0 Utp14 protein Methyltransf_23 PF13489.6 CDJ61340.1 - 1e-10 41.7 0.0 1e-10 41.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDJ61340.1 - 6.8e-08 33.1 2.1 6.8e-06 26.7 0.4 3.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDJ61340.1 - 9e-07 29.5 0.9 0.0099 16.5 0.1 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 CDJ61340.1 - 3.3e-06 27.0 9.7 0.00022 21.1 0.1 3.3 3 0 0 3 3 3 2 Methyltransferase domain FtsJ PF01728.19 CDJ61340.1 - 0.0023 18.0 0.1 0.0094 16.1 0.0 2.0 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CDJ61340.1 - 0.0032 18.2 0.2 0.0032 18.2 0.2 3.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDJ61340.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CDJ61340.1 - 0.32 12.0 0.2 0.32 12.0 0.2 4.4 4 1 0 4 4 4 0 Methyltransferase domain Glycolytic PF00274.19 CDJ61342.1 - 2.2e-168 559.4 0.0 2.5e-168 559.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Rad10 PF03834.14 CDJ61343.1 - 7.8e-25 87.1 0.0 1.6e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 CDJ61343.1 - 0.00016 21.3 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 CDJ61343.1 - 0.013 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 CDJ61343.1 - 0.14 12.7 0.0 0.55 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3464 PF11947.8 CDJ61343.1 - 3.9 7.2 5.6 0.68 9.7 1.8 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Thioredoxin PF00085.20 CDJ61344.1 - 4.5e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDJ61344.1 - 0.0036 17.2 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Antimicrobial_1 PF08018.11 CDJ61344.1 - 0.49 10.6 2.3 1.1 9.5 2.3 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide ketoacyl-synt PF00109.26 CDJ61345.1 - 9.6e-79 264.5 0.5 9.6e-79 264.5 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 CDJ61345.1 - 2.5e-75 253.7 0.0 6.8e-75 252.3 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme PS-DH PF14765.6 CDJ61345.1 - 9.3e-41 140.0 0.0 1.8e-30 106.2 0.0 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CDJ61345.1 - 1.1e-40 138.3 0.0 3.4e-40 136.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CDJ61345.1 - 1.4e-21 77.4 0.0 2.6e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ADH_zinc_N PF00107.26 CDJ61345.1 - 4.9e-12 46.0 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 CDJ61345.1 - 2.3e-11 43.9 0.3 8.1e-11 42.1 0.3 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 CDJ61345.1 - 5.2e-09 36.6 0.0 1.5e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDJ61345.1 - 8.5e-05 22.0 0.2 0.00021 20.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 CDJ61345.1 - 0.0002 21.2 0.5 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AMP-binding_C_2 PF14535.6 CDJ61345.1 - 0.0016 18.7 0.0 0.005 17.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.10 CDJ61345.1 - 0.11 12.3 1.1 0.32 10.9 0.5 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N_2 PF13602.6 CDJ61345.1 - 0.13 13.3 0.0 0.79 10.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Helicase_C PF00271.31 CDJ61347.1 - 2.1e-11 44.1 0.2 2.3e-10 40.8 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SR-25 PF10500.9 CDJ61347.1 - 0.00012 21.8 12.3 0.00012 21.8 12.3 7.4 6 1 0 6 6 6 3 Nuclear RNA-splicing-associated protein DUF4667 PF15700.5 CDJ61347.1 - 0.0049 17.0 4.5 0.0049 17.0 4.5 7.7 4 3 1 5 5 5 1 Domain of unknown function (DUF4667) Pox_A3L PF05288.11 CDJ61347.1 - 0.065 13.2 0.3 0.23 11.5 0.3 2.0 1 0 0 1 1 1 0 Poxvirus A3L Protein LYRIC PF15686.5 CDJ61349.1 - 0.03 13.9 0.2 0.03 13.9 0.2 3.5 1 1 1 3 3 3 0 Lysine-rich CEACAM1 co-isolated protein family TMEM125 PF15109.6 CDJ61349.1 - 0.033 14.5 0.3 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 TMEM125 protein family SARAF PF06682.12 CDJ61349.1 - 0.074 12.7 33.8 0.054 13.1 7.5 3.2 1 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Ribosomal_60s PF00428.19 CDJ61349.1 - 0.35 11.5 36.6 0.15 12.7 7.0 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein FxsA PF04186.13 CDJ61349.1 - 0.45 10.7 10.3 0.49 10.5 0.0 3.7 4 0 0 4 4 4 0 FxsA cytoplasmic membrane protein DUF3995 PF13160.6 CDJ61349.1 - 1.1 9.6 13.3 0.028 14.8 2.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) OATP PF03137.20 CDJ61349.1 - 1.5 7.0 3.3 0.53 8.5 0.3 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3402 PF11882.8 CDJ61349.1 - 4.8 6.2 13.7 0.74 8.9 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3402) YTH PF04146.15 CDJ61350.1 - 7.7e-14 52.0 11.8 9.1e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 YT521-B-like domain eIF-3_zeta PF05091.12 CDJ61350.1 - 0.00097 18.2 8.9 0.00097 18.2 8.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 CDJ61350.1 - 0.054 12.9 3.0 0.071 12.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 CDJ61350.1 - 1.8 8.5 30.3 2.7 7.9 30.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CDJ61350.1 - 2.1 8.1 12.1 2.5 7.9 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CDJ61350.1 - 2.1 8.4 4.6 2.2 8.3 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP12 PF07542.11 CDJ61351.1 - 5.2e-09 36.3 1.6 5.2e-09 36.3 1.6 2.1 2 0 0 2 2 2 1 ATP12 chaperone protein HisKA PF00512.25 CDJ61351.1 - 0.0056 16.7 1.4 0.025 14.6 1.4 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TMEM252 PF15664.5 CDJ61351.1 - 0.014 15.1 0.4 0.052 13.3 0.4 1.9 1 0 0 1 1 1 0 Transmembrane protein 252 family Spt20 PF12090.8 CDJ61351.1 - 0.31 10.6 16.3 0.1 12.2 9.3 2.4 2 0 0 2 2 2 0 Spt20 family TMEM51 PF15345.6 CDJ61352.1 - 0.0051 16.7 1.3 0.0051 16.7 1.3 2.7 2 1 0 2 2 2 1 Transmembrane protein 51 Tau95_N PF17682.1 CDJ61352.1 - 0.032 14.4 2.3 0.032 14.4 2.3 1.9 2 1 0 2 2 2 0 Tau95 Triple barrel domain Folate_carrier PF01770.18 CDJ61352.1 - 0.13 10.9 0.1 0.26 10.0 0.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier FAM76 PF16046.5 CDJ61352.1 - 0.23 10.8 15.8 0.063 12.6 12.5 1.6 1 1 0 1 1 1 0 FAM76 protein DUF572 PF04502.13 CDJ61352.1 - 0.29 10.7 10.4 0.48 10.0 10.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAP_RNA-bind PF04926.15 CDJ61352.1 - 0.54 9.9 5.4 2.5 7.7 0.4 2.4 2 1 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain SR-25 PF10500.9 CDJ61352.1 - 0.78 9.3 22.4 0.39 10.3 10.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.13 CDJ61352.1 - 0.8 10.3 20.1 4.6 7.9 0.2 4.9 4 1 1 5 5 5 0 Oxaloacetate decarboxylase, gamma chain CSG2 PF16965.5 CDJ61352.1 - 0.82 8.6 2.6 0.48 9.3 0.3 1.7 2 0 0 2 2 2 0 Ceramide synthase regulator Ctr PF04145.15 CDJ61352.1 - 1.1 9.9 5.9 13 6.4 0.4 2.3 2 0 0 2 2 2 0 Ctr copper transporter family RskA PF10099.9 CDJ61352.1 - 2 8.7 37.0 0.19 12.0 6.5 3.7 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 CDJ61352.1 - 3.3 8.7 12.6 0.097 13.6 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 CDJ61352.1 - 6.3 5.6 22.8 0.57 9.1 12.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CCDC53 PF10152.9 CDJ61352.1 - 8.9 6.7 18.7 2.1 8.7 8.0 3.0 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex CASP_C PF08172.12 CDJ61353.1 - 0.94 8.8 11.3 1 8.7 11.3 1.0 1 0 0 1 1 1 0 CASP C terminal DUF4834 PF16118.5 CDJ61353.1 - 2.1 9.4 4.4 2.2 9.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Secretin_N_2 PF07655.13 CDJ61353.1 - 4.4 7.9 32.6 6.9 7.3 32.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain NAM-associated PF14303.6 CDJ61353.1 - 6.1 7.5 15.9 6.8 7.4 15.9 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RskA PF10099.9 CDJ61355.1 - 0.00077 19.8 23.5 0.00077 19.8 23.5 2.1 1 1 1 2 2 1 1 Anti-sigma-K factor rskA Peptidase_S49_N PF08496.10 CDJ61355.1 - 0.01 15.9 7.0 0.01 15.9 7.0 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal SARAF PF06682.12 CDJ61355.1 - 0.037 13.7 16.2 0.04 13.6 16.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PIP5K PF01504.18 CDJ61355.1 - 0.083 12.1 10.4 0.086 12.1 10.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Serinc PF03348.15 CDJ61355.1 - 0.14 11.0 10.7 0.16 10.8 10.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 CDJ61355.1 - 0.27 10.2 17.9 0.25 10.3 17.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ61355.1 - 0.27 9.6 7.0 0.33 9.3 7.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 CDJ61355.1 - 0.27 9.5 12.8 0.31 9.3 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4813 PF16072.5 CDJ61355.1 - 0.28 10.8 15.8 0.35 10.5 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RR_TM4-6 PF06459.12 CDJ61355.1 - 0.29 10.9 18.1 0.33 10.7 18.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1754 PF08555.10 CDJ61355.1 - 0.34 11.7 17.4 0.14 13.0 15.1 1.5 2 0 0 2 2 1 0 Eukaryotic family of unknown function (DUF1754) PA26 PF04636.13 CDJ61355.1 - 0.36 9.7 13.3 0.36 9.7 13.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) X PF00739.19 CDJ61355.1 - 0.41 10.8 4.6 0.5 10.5 4.6 1.1 1 0 0 1 1 1 0 Trans-activation protein X CLN3 PF02487.17 CDJ61355.1 - 0.44 9.5 11.2 0.44 9.5 11.2 1.3 1 0 0 1 1 1 0 CLN3 protein PPL5 PF18168.1 CDJ61355.1 - 0.46 9.7 11.7 0.61 9.3 11.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 CDJ61355.1 - 0.47 9.4 13.1 0.53 9.2 13.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CDJ61355.1 - 0.61 8.8 24.2 0.66 8.7 24.2 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CDJ61355.1 - 0.64 8.8 14.8 0.65 8.8 14.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Velvet PF11754.8 CDJ61355.1 - 0.72 9.7 19.7 1.2 9.1 19.7 1.4 1 0 0 1 1 1 0 Velvet factor DUF2464 PF10240.9 CDJ61355.1 - 0.75 9.3 11.8 0.77 9.3 11.8 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 STAC2_u1 PF16664.5 CDJ61355.1 - 0.75 10.3 17.1 0.23 11.9 14.4 1.5 2 0 0 2 2 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF2370 PF10176.9 CDJ61355.1 - 1.6 8.3 11.1 2.2 7.9 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Nop53 PF07767.11 CDJ61355.1 - 1.6 8.0 26.9 1.7 7.9 26.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) O-antigen_lig PF13425.6 CDJ61355.1 - 2 7.1 9.7 2.2 7.0 9.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.16 CDJ61355.1 - 2.1 8.4 15.6 2.9 7.9 15.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAJIN PF15077.6 CDJ61355.1 - 2.1 8.1 17.0 2.4 7.9 17.0 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Hid1 PF12722.7 CDJ61355.1 - 2.2 6.3 18.3 2.1 6.4 18.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.10 CDJ61355.1 - 2.4 6.7 53.1 3.1 6.4 53.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hamartin PF04388.12 CDJ61355.1 - 2.7 6.6 23.2 2.9 6.4 23.2 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_U57 PF05582.12 CDJ61355.1 - 2.9 7.1 12.1 4.3 6.5 12.1 1.3 1 0 0 1 1 1 0 YabG peptidase U57 V_ATPase_I PF01496.19 CDJ61355.1 - 3.2 5.5 18.3 3.8 5.3 18.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.14 CDJ61355.1 - 3.4 6.9 42.4 4.5 6.5 42.4 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase XRN_M PF17846.1 CDJ61355.1 - 4 6.3 12.7 4.3 6.2 12.7 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Membralin PF09746.9 CDJ61355.1 - 4.1 6.3 13.8 5.1 6.0 13.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF1151 PF06625.11 CDJ61355.1 - 4.4 7.3 30.9 6.1 6.8 30.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) LMBR1 PF04791.16 CDJ61355.1 - 4.8 6.0 12.0 4.9 6.0 12.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 CDJ61355.1 - 5.2 5.2 39.1 6.3 4.9 39.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 CDJ61355.1 - 7.3 5.0 18.4 7.7 4.9 18.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 HCO3_cotransp PF00955.21 CDJ61355.1 - 7.6 5.2 8.3 8 5.2 8.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family CCSAP PF15748.5 CDJ61355.1 - 9.1 6.4 27.3 12 6.0 27.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AUX_IAA PF02309.16 CDJ61355.1 - 9.7 6.0 17.0 14 5.5 17.0 1.2 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.13 CDJ61356.1 - 0.004 17.2 13.2 0.0043 17.1 13.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1645 PF07816.11 CDJ61356.1 - 0.014 16.0 7.2 0.014 16.0 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF4711 PF15829.5 CDJ61356.1 - 0.18 11.7 3.6 0.26 11.2 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) GREB1 PF15782.5 CDJ61356.1 - 0.4 7.8 11.2 0.62 7.1 11.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer K_channel_TID PF07941.11 CDJ61356.1 - 0.49 10.9 7.0 1.6 9.2 2.9 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Presenilin PF01080.17 CDJ61356.1 - 0.65 8.7 9.3 0.88 8.3 9.3 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CDJ61356.1 - 1.2 7.8 9.3 1.3 7.6 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ61356.1 - 2.8 6.1 17.7 3.5 5.8 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDJ61357.1 - 0.01 15.9 44.1 0.33 10.9 31.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 CDJ61357.1 - 0.017 14.9 14.0 0.31 10.8 7.9 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 CDJ61357.1 - 0.019 15.6 23.7 0.43 11.2 15.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Torus PF16131.5 CDJ61357.1 - 0.091 13.5 0.4 0.091 13.5 0.4 2.4 2 1 0 2 2 1 0 Torus domain EPL1 PF10513.9 CDJ61357.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.4 2 1 0 2 2 1 0 Enhancer of polycomb-like Velvet PF11754.8 CDJ61357.1 - 0.19 11.6 11.5 1.1 9.1 7.4 2.1 2 0 0 2 2 2 0 Velvet factor Gti1_Pac2 PF09729.9 CDJ61357.1 - 0.38 10.8 8.4 13 5.9 0.0 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Presenilin PF01080.17 CDJ61357.1 - 0.4 9.4 18.2 1.2 7.9 10.7 2.1 2 0 0 2 2 2 0 Presenilin BORG_CEP PF14957.6 CDJ61357.1 - 0.78 10.9 8.7 6.6 7.9 4.3 2.3 2 0 0 2 2 2 0 Cdc42 effector MMR1 PF08505.10 CDJ61357.1 - 4.2 7.6 24.9 6.7 6.9 4.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF2052 PF09747.9 CDJ61357.1 - 4.9 7.2 17.3 3.4 7.8 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PIEZO PF15917.5 CDJ61357.1 - 5.6 6.4 26.5 0.032 13.7 2.4 2.1 2 0 0 2 2 2 0 Piezo Neur_chan_memb PF02932.16 CDJ61357.1 - 6.4 6.8 15.7 8 6.4 8.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 CDJ61357.1 - 6.4 6.1 14.2 8.7 5.7 0.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CDJ61357.1 - 6.9 5.8 5.9 23 4.0 3.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Membralin PF09746.9 CDJ61357.1 - 7.2 5.5 11.7 6.9 5.6 5.4 2.0 2 0 0 2 2 2 0 Tumour-associated protein DUF4638 PF15472.6 CDJ61357.1 - 7.4 6.2 13.8 15 5.2 8.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Rtf2 PF04641.12 CDJ61357.1 - 8 5.7 13.7 2.4 7.5 0.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger CPSF100_C PF13299.6 CDJ61357.1 - 8.9 6.5 16.0 12 6.0 5.9 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Rhodanese PF00581.20 CDJ61358.1 - 7.5e-11 42.5 2.3 8.6e-05 23.0 0.6 3.1 2 1 0 2 2 2 2 Rhodanese-like domain FAM60A PF15396.6 CDJ61358.1 - 0.00059 19.9 16.8 0.0099 15.9 0.1 2.5 2 0 0 2 2 2 1 Protein Family FAM60A SLC12 PF03522.15 CDJ61358.1 - 0.00078 18.6 4.7 0.00078 18.6 4.7 2.4 2 1 0 2 2 2 1 Solute carrier family 12 Spem1 PF15670.5 CDJ61358.1 - 0.0069 16.0 9.3 0.0069 16.0 9.3 2.4 3 0 0 3 3 2 1 Spermatid maturation protein 1 SUIM_assoc PF16619.5 CDJ61358.1 - 0.014 15.4 1.4 0.014 15.4 1.4 7.1 4 1 1 5 5 2 0 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 CDJ61358.1 - 0.04 12.9 19.2 0.094 11.7 15.6 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIP5K PF01504.18 CDJ61358.1 - 0.056 12.7 10.9 0.98 8.6 6.8 2.4 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4366 PF14283.6 CDJ61358.1 - 0.059 13.4 5.5 0.13 12.3 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) 60KD_IMP PF02096.20 CDJ61358.1 - 0.062 13.2 0.3 0.062 13.2 0.3 3.7 3 1 1 4 4 2 0 60Kd inner membrane protein Dicty_REP PF05086.12 CDJ61358.1 - 0.12 10.3 1.5 0.16 9.9 1.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 CDJ61358.1 - 0.21 10.2 21.8 0.055 12.1 3.0 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup ThiC-associated PF13667.6 CDJ61358.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.8 4 0 0 4 4 2 0 ThiC-associated domain DUF4407 PF14362.6 CDJ61358.1 - 0.88 8.9 22.7 5.4 6.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Connexin PF00029.19 CDJ61358.1 - 0.89 9.3 10.4 4.5 7.0 9.4 2.4 2 0 0 2 2 2 0 Connexin CDC45 PF02724.14 CDJ61358.1 - 1 7.6 14.7 0.39 8.9 9.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF2370 PF10176.9 CDJ61358.1 - 1.3 8.7 6.5 14 5.3 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) RNA_pol_Rpc4 PF05132.14 CDJ61358.1 - 1.4 9.3 27.8 0.054 13.9 9.3 3.6 3 1 0 3 3 3 0 RNA polymerase III RPC4 RAP1 PF07218.11 CDJ61358.1 - 1.7 6.8 9.5 2.7 6.2 9.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Endostatin PF06482.11 CDJ61358.1 - 2.2 7.7 19.4 3 7.2 15.2 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin GAGA_bind PF06217.12 CDJ61358.1 - 2.3 8.5 19.0 0.47 10.7 13.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4064 PF13273.6 CDJ61358.1 - 2.3 8.5 0.0 2.3 8.5 0.0 3.4 2 1 0 2 2 1 0 Protein of unknown function (DUF4064) DUF913 PF06025.12 CDJ61358.1 - 3.2 6.6 13.9 1.9 7.4 5.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ureide_permease PF07168.11 CDJ61358.1 - 3.6 6.2 7.5 41 2.8 0.0 2.2 2 0 0 2 2 2 0 Ureide permease SID-1_RNA_chan PF13965.6 CDJ61358.1 - 4.1 5.7 5.9 3.8 5.8 4.5 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ61358.1 - 6.5 6.2 22.5 38 3.7 20.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CDJ61358.1 - 9.2 6.0 24.1 0.27 11.1 14.3 2.9 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 SNase PF00565.17 CDJ61359.1 - 2e-07 31.5 0.7 0.029 14.8 0.0 3.6 3 0 0 3 3 3 2 Staphylococcal nuclease homologue PBP1_TM PF14812.6 CDJ61359.1 - 0.021 15.2 0.9 0.021 15.2 0.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spore_III_AF PF09581.10 CDJ61359.1 - 0.029 14.4 0.8 0.029 14.4 0.8 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF913 PF06025.12 CDJ61359.1 - 0.087 11.8 6.3 0.85 8.5 1.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Otopetrin PF03189.13 CDJ61359.1 - 0.28 9.9 2.0 0.38 9.5 0.2 1.8 2 0 0 2 2 2 0 Otopetrin SpoIIP PF07454.11 CDJ61359.1 - 0.31 10.4 11.4 0.23 10.9 3.9 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CLN3 PF02487.17 CDJ61359.1 - 0.45 9.5 7.0 0.2 10.7 2.2 2.1 2 0 0 2 2 2 0 CLN3 protein LMBR1 PF04791.16 CDJ61359.1 - 0.54 9.1 2.0 0.94 8.3 2.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RNA_pol_Rpc4 PF05132.14 CDJ61359.1 - 0.66 10.4 15.5 2.3 8.6 1.9 3.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF572 PF04502.13 CDJ61359.1 - 0.72 9.4 12.2 3 7.4 1.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Connexin PF00029.19 CDJ61359.1 - 0.75 9.5 9.1 0.075 12.8 1.5 2.2 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 CDJ61359.1 - 0.83 8.3 15.7 0.31 9.8 4.2 2.2 2 0 0 2 2 2 0 Presenilin OATP PF03137.20 CDJ61359.1 - 0.92 7.7 7.3 0.054 11.8 0.9 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 60KD_IMP PF02096.20 CDJ61359.1 - 1.5 8.7 4.4 0.58 10.0 0.5 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein NPR3 PF03666.13 CDJ61359.1 - 1.5 7.5 8.7 0.76 8.5 1.9 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CDJ61359.1 - 1.7 8.7 8.9 6.3 6.8 0.1 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region BSMAP PF12280.8 CDJ61359.1 - 2.3 8.4 8.0 0.71 10.1 1.7 2.4 2 0 0 2 2 2 0 Brain specific membrane anchored protein Band_3_cyto PF07565.13 CDJ61359.1 - 2.4 7.9 10.1 17 5.1 6.2 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Hydin_ADK PF17213.3 CDJ61359.1 - 3.7 7.8 17.9 2 8.7 4.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF2052 PF09747.9 CDJ61359.1 - 6.3 6.9 13.5 0.55 10.3 1.6 3.0 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Endostatin PF06482.11 CDJ61359.1 - 7 6.0 11.6 7.2 6.0 3.3 2.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Mit_KHE1 PF10173.9 CDJ61359.1 - 7.8 6.5 6.5 2.7 8.0 1.8 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Peroxin-13_N PF04088.13 CDJ61359.1 - 9.4 6.5 7.6 15 5.9 1.8 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CSG2 PF16965.5 CDJ61359.1 - 9.9 5.0 7.8 0.5 9.2 1.8 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator SLC12 PF03522.15 CDJ61359.1 - 10 5.1 11.6 1.9 7.4 3.8 2.2 2 0 0 2 2 2 0 Solute carrier family 12 DUF5327 PF17261.2 CDJ61361.1 - 0.035 14.8 4.1 0.035 14.8 4.1 3.6 3 1 0 3 3 3 0 Family of unknown function (DUF5327) CCDC117 PF15810.5 CDJ61361.1 - 0.048 14.0 1.0 0.048 14.0 1.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 117 SARAF PF06682.12 CDJ61361.1 - 2.3 7.8 16.2 3.8 7.1 4.2 2.6 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SF3b10 PF07189.11 CDJ61362.1 - 3.9e-32 110.2 0.0 3.9e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Splicing factor 3B subunit 10 (SF3b10) DUF4820 PF16091.5 CDJ61362.1 - 0.013 14.9 2.4 0.016 14.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Coilin_N PF15862.5 CDJ61362.1 - 0.092 12.6 4.8 0.12 12.1 4.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 CDJ61362.1 - 0.15 10.8 2.0 0.13 11.0 2.0 1.1 1 0 0 1 1 1 0 Presenilin FYDLN_acid PF09538.10 CDJ61362.1 - 0.23 12.2 12.4 0.32 11.7 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Roughex PF06020.11 CDJ61362.1 - 0.4 9.7 5.5 0.45 9.6 5.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TRAP_alpha PF03896.16 CDJ61362.1 - 0.44 9.7 7.7 0.62 9.2 7.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 CDJ61362.1 - 3.5 8.1 8.3 5 7.5 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 AIF_C PF14721.6 CDJ61362.1 - 8 6.8 7.6 12 6.3 7.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RskA PF10099.9 CDJ61363.1 - 6.1e-05 23.4 28.7 0.073 13.4 0.0 4.3 1 1 3 4 4 4 3 Anti-sigma-K factor rskA DnaJ PF00226.31 CDJ61363.1 - 0.0002 21.4 0.3 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Utp14 PF04615.13 CDJ61366.1 - 0.67 8.5 43.8 0.82 8.2 43.8 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 CDJ61367.1 - 0.0024 17.9 4.8 0.0024 17.9 4.8 4.4 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 CDJ61367.1 - 8.8 5.1 9.6 2.3 7.0 0.3 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein SAMP PF05924.11 CDJ61368.1 - 0.094 12.0 1.2 0.26 10.6 1.2 1.7 1 0 0 1 1 1 0 SAMP Motif Phage_Integr_2 PF13009.6 CDJ61368.1 - 3.8 6.5 11.4 0.066 12.3 2.7 2.3 2 0 0 2 2 2 0 Putative phage integrase DUF1515 PF07439.11 CDJ61369.1 - 1.4 9.0 5.5 0.4 10.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) cwf21 PF08312.12 CDJ61370.1 - 4.7e-06 26.6 10.4 4.7e-06 26.6 10.4 3.3 3 0 0 3 3 3 1 cwf21 domain Pheromone PF08015.11 CDJ61370.1 - 0.85 10.7 10.1 2.9 9.0 10.1 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone DegQ PF08181.11 CDJ61371.1 - 1.4 9.1 2.7 2.2 8.4 0.3 2.4 2 0 0 2 2 2 0 DegQ (SacQ) family H_PPase PF03030.16 CDJ61372.1 - 2e-215 717.3 25.8 2.5e-215 717.0 25.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase IPPT PF01715.17 CDJ61373.1 - 3.2e-61 207.1 0.0 7.2e-61 205.9 0.0 1.5 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 CDJ61373.1 - 0.0029 17.0 0.9 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_16 PF13191.6 CDJ61373.1 - 0.004 17.6 0.2 0.011 16.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDJ61373.1 - 0.014 15.5 0.3 0.058 13.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDJ61373.1 - 0.015 15.6 0.1 0.046 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDJ61373.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein baeRF_family3 PF18845.1 CDJ61373.1 - 0.033 14.4 0.3 0.082 13.2 0.3 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 HTH_17 PF12728.7 CDJ61373.1 - 0.045 13.9 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain ATPase_2 PF01637.18 CDJ61373.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CDJ61373.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CDJ61373.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain MOZART1 PF12554.8 CDJ61373.1 - 0.14 11.9 0.4 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated NTPase_1 PF03266.15 CDJ61373.1 - 0.15 11.9 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 NTPase DEK_C PF08766.11 CDJ61373.1 - 4 7.4 5.2 0.71 9.8 0.6 2.1 2 0 0 2 2 2 0 DEK C terminal domain PGAP1 PF07819.13 CDJ61374.1 - 1.2e-09 38.2 0.3 5.1e-09 36.2 0.3 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CDJ61374.1 - 0.017 14.7 0.5 0.032 13.7 0.1 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) zf-rbx1 PF12678.7 CDJ61375.1 - 1.1e-08 35.3 2.7 2.4e-08 34.1 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDJ61375.1 - 1.7e-06 28.2 4.5 1.7e-06 28.2 4.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDJ61375.1 - 0.00019 21.2 4.8 0.00042 20.1 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDJ61375.1 - 0.00022 21.2 0.3 0.00043 20.3 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CDJ61375.1 - 0.00048 20.1 2.8 0.0013 18.8 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDJ61375.1 - 0.001 18.9 2.2 0.001 18.9 2.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDJ61375.1 - 0.0081 16.1 2.8 0.019 14.9 2.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDJ61375.1 - 0.018 14.9 3.2 0.018 14.9 3.2 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CDJ61375.1 - 1.7 8.5 8.2 0.05 13.4 2.0 1.7 2 0 0 2 2 2 0 RING-like zinc finger TFIIA PF03153.13 CDJ61376.1 - 0.35 10.8 16.8 0.36 10.8 16.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 CDJ61376.1 - 0.37 10.1 6.3 0.44 9.9 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 CDJ61376.1 - 0.41 10.8 5.8 0.47 10.6 5.8 1.1 1 0 0 1 1 1 0 DDHD domain Menin PF05053.13 CDJ61376.1 - 0.41 8.9 11.7 0.46 8.8 11.7 1.0 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.12 CDJ61376.1 - 0.65 9.8 8.4 0.79 9.5 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Baculo_PP31 PF05311.11 CDJ61376.1 - 0.67 9.4 5.5 0.81 9.1 5.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) XAP5 PF04921.14 CDJ61376.1 - 1 9.1 8.7 1.4 8.7 8.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Presenilin PF01080.17 CDJ61376.1 - 1.1 8.0 9.9 1 8.0 9.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ61376.1 - 1.1 9.3 5.6 1.2 9.2 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kinesin_assoc PF16183.5 CDJ61376.1 - 1.1 9.4 3.7 2.2 8.4 3.7 1.7 1 1 0 1 1 1 0 Kinesin-associated Med3 PF11593.8 CDJ61376.1 - 1.6 7.8 20.2 1.9 7.6 20.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CPSF100_C PF13299.6 CDJ61376.1 - 1.8 8.7 6.5 2.2 8.4 6.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 CDJ61376.1 - 5 5.1 7.6 4.9 5.2 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 CDJ61376.1 - 8.8 5.9 17.0 12 5.5 17.0 1.1 1 0 0 1 1 1 0 Spt20 family Inositol_P PF00459.25 CDJ61377.1 - 8.5e-25 87.8 0.0 1.2e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 CDJ61377.1 - 0.0013 18.3 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF3223 PF11523.8 CDJ61379.1 - 3.7e-16 59.7 0.5 3.6e-15 56.6 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) La PF05383.17 CDJ61379.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 La domain FHA PF00498.26 CDJ61380.1 - 1.5e-18 66.8 0.6 4.1e-09 36.6 0.3 2.7 2 0 0 2 2 2 2 FHA domain zf-C3HC4_2 PF13923.6 CDJ61380.1 - 7.9e-08 32.0 9.8 2.3e-07 30.5 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDJ61380.1 - 3e-07 30.2 7.8 4.4e-07 29.7 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDJ61380.1 - 3.1e-07 30.3 9.9 1.1e-06 28.5 9.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDJ61380.1 - 7.4e-07 29.2 10.5 7.4e-07 29.2 10.5 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDJ61380.1 - 1.3e-06 28.2 10.0 5.3e-06 26.2 10.0 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDJ61380.1 - 1.3e-06 28.6 9.4 6.7e-06 26.3 9.4 2.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDJ61380.1 - 1.5e-05 24.8 6.6 5.6e-05 22.9 6.6 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CDJ61380.1 - 0.0001 22.3 7.8 0.0001 22.3 7.8 2.5 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 CDJ61380.1 - 0.00014 21.8 8.4 0.00014 21.8 8.4 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CDJ61380.1 - 0.0092 15.8 2.5 0.032 14.0 2.5 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDJ61380.1 - 0.0098 16.2 3.6 0.072 13.4 3.6 2.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 CDJ61380.1 - 0.13 12.5 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 U-box domain SPX PF03105.19 CDJ61380.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.4 2 2 0 2 2 1 0 SPX domain RRM_1 PF00076.22 CDJ61381.1 - 5.1e-25 87.1 0.1 1.9e-11 43.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDJ61381.1 - 9.1e-09 35.3 0.1 0.0023 18.0 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif DUF5558 PF17713.1 CDJ61381.1 - 0.046 14.1 2.6 0.12 12.8 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5558) DUF2722 PF10846.8 CDJ61382.1 - 1.1e-06 27.9 22.5 0.002 17.2 0.0 3.7 3 1 0 3 3 3 3 Protein of unknown function (DUF2722) BAF1_ABF1 PF04684.13 CDJ61382.1 - 0.00025 20.3 13.3 0.00025 20.3 13.3 2.1 3 0 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor D123 PF07065.14 CDJ61382.1 - 0.00084 18.6 0.0 0.00084 18.6 0.0 5.7 4 2 0 4 4 4 1 D123 CDC45 PF02724.14 CDJ61382.1 - 0.0063 14.9 3.8 0.011 14.0 3.8 1.3 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 CDJ61382.1 - 0.2 11.1 11.6 0.013 15.0 5.6 2.0 3 0 0 3 3 3 0 SDA1 Utp14 PF04615.13 CDJ61382.1 - 0.22 10.0 16.7 0.045 12.3 13.0 1.7 2 0 0 2 2 2 0 Utp14 protein Otopetrin PF03189.13 CDJ61382.1 - 7.5 5.3 5.5 23 3.6 5.6 1.6 1 1 0 1 1 1 0 Otopetrin EamA PF00892.20 CDJ61383.1 - 1.4e-09 38.3 29.9 1.1e-06 28.9 17.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CDJ61383.1 - 0.0087 15.4 0.7 0.0087 15.4 0.7 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family His_Phos_2 PF00328.22 CDJ61385.1 - 4e-09 36.3 1.0 0.0066 15.8 0.0 3.6 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) MMR_HSR1_Xtn PF16897.5 CDJ61386.1 - 6.6e-42 141.8 0.2 1.3e-41 140.9 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDJ61386.1 - 4.8e-23 81.0 0.1 1e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDJ61386.1 - 8.5e-21 74.2 0.0 1.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDJ61386.1 - 3.4e-11 42.9 0.1 1.6e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDJ61386.1 - 0.0002 21.5 0.0 0.54 10.3 0.0 2.6 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 CDJ61386.1 - 0.00028 20.0 0.2 0.0022 17.0 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CDJ61386.1 - 0.057 13.3 0.9 0.7 9.8 0.1 2.7 2 1 1 3 3 3 0 RsgA GTPase AIG1 PF04548.16 CDJ61386.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 CDJ61386.1 - 0.12 11.9 0.1 4 6.9 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF3800 PF12686.7 CDJ61388.1 - 2.6e-05 24.9 0.0 1.6 9.4 0.0 6.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) Spt20 PF12090.8 CDJ61391.1 - 0.0073 15.9 3.3 0.0073 15.9 3.3 3.2 3 0 0 3 3 3 2 Spt20 family RskA PF10099.9 CDJ61391.1 - 0.019 15.3 0.5 0.019 15.3 0.5 4.4 2 2 2 4 4 4 0 Anti-sigma-K factor rskA HTH_Tnp_Tc3_2 PF01498.18 CDJ61391.1 - 0.079 13.2 0.6 0.18 12.1 0.2 1.8 2 0 0 2 2 2 0 Transposase SUIM_assoc PF16619.5 CDJ61391.1 - 0.21 11.7 38.4 0.57 10.3 10.0 3.7 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ANAPC1 PF12859.7 CDJ61391.1 - 0.28 11.8 4.6 0.52 10.9 2.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF1635 PF07795.11 CDJ61391.1 - 3.4 7.5 18.9 0.096 12.5 5.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) Band_3_cyto PF07565.13 CDJ61391.1 - 5 6.8 8.2 4.2 7.1 3.1 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MMR1 PF08505.10 CDJ61391.1 - 5.5 7.2 19.5 2.3 8.4 0.1 2.6 2 1 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein ANAPC_CDC26 PF10471.9 CDJ61393.1 - 0.051 14.4 12.7 1 10.2 9.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Cyt_bd_oxida_II PF02322.15 CDJ61393.1 - 0.07 12.5 0.1 0.097 12.0 0.1 1.3 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II TFIIA PF03153.13 CDJ61393.1 - 0.11 12.5 22.7 0.14 12.1 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ61393.1 - 1.3 9.3 32.4 0.34 11.2 0.2 2.6 1 1 0 2 2 2 0 Anti-sigma-K factor rskA TAS2R PF05296.13 CDJ61394.1 - 0.13 11.3 1.6 0.27 10.3 1.6 1.4 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) UCH PF00443.29 CDJ61395.1 - 1e-11 44.8 0.0 4.3e-11 42.8 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDJ61395.1 - 1.9e-05 24.4 7.1 0.00085 19.0 0.0 4.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_ab PF00006.25 CDJ61396.1 - 1.3e-65 221.0 0.0 1.9e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDJ61396.1 - 1e-07 32.3 0.1 1.8e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Spt20 PF12090.8 CDJ61398.1 - 0.0033 17.1 9.2 0.0033 17.1 9.2 4.4 4 0 0 4 4 4 2 Spt20 family DUF2722 PF10846.8 CDJ61398.1 - 0.0054 15.7 3.0 0.0054 15.7 3.0 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) IMUP PF15761.5 CDJ61398.1 - 4.1 8.2 43.1 0.44 11.3 0.3 5.5 5 0 0 5 5 5 0 Immortalisation up-regulated protein Utp14 PF04615.13 CDJ61399.1 - 0.0014 17.3 11.1 0.0014 17.3 11.1 6.5 2 2 2 5 5 5 1 Utp14 protein TMEM214 PF10151.9 CDJ61400.1 - 0.18 10.2 3.0 0.31 9.5 3.0 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator eIF3_subunit PF08597.10 CDJ61400.1 - 0.65 9.9 11.9 1.9 8.3 7.5 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DDHD PF02862.17 CDJ61400.1 - 0.95 9.6 10.9 0.33 11.1 0.7 4.0 4 0 0 4 4 4 0 DDHD domain Pex26 PF07163.12 CDJ61401.1 - 0.00073 18.9 0.7 0.00094 18.6 0.7 1.1 1 0 0 1 1 1 1 Pex26 protein DUF2722 PF10846.8 CDJ61401.1 - 0.011 14.7 4.2 0.012 14.6 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3824 PF12868.7 CDJ61401.1 - 0.045 14.4 0.2 0.062 14.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Synuclein PF01387.17 CDJ61401.1 - 0.15 12.3 1.0 0.18 12.0 1.0 1.1 1 0 0 1 1 1 0 Synuclein Androgen_recep PF02166.16 CDJ61401.1 - 0.18 10.6 15.6 0.22 10.3 15.6 1.1 1 0 0 1 1 1 0 Androgen receptor GCIP PF13324.6 CDJ61401.1 - 0.47 10.0 5.4 0.29 10.7 3.7 1.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting UPF0239 PF06783.11 CDJ61401.1 - 1.6 9.0 11.8 0.43 10.8 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) DUF3682 PF12446.8 CDJ61401.1 - 2.4 8.7 10.7 3 8.3 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RskA PF10099.9 CDJ61401.1 - 9.9 6.4 8.3 2.5 8.4 5.2 1.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA BRF1 PF07741.13 CDJ61402.1 - 0.01 16.1 1.8 0.01 16.1 1.8 6.7 5 3 0 5 5 5 0 Brf1-like TBP-binding domain Glycos_transf_1 PF00534.20 CDJ61403.1 - 2.8e-06 27.0 0.3 0.0099 15.4 0.1 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 ALG11_N PF15924.5 CDJ61403.1 - 3.3e-06 27.3 2.6 0.0002 21.5 0.2 4.1 2 1 1 3 3 3 1 ALG11 mannosyltransferase N-terminus RskA PF10099.9 CDJ61403.1 - 0.00014 22.2 28.4 0.0019 18.5 7.6 8.1 6 2 1 7 7 7 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ61403.1 - 0.0015 17.6 5.7 0.0015 17.6 5.7 7.7 5 2 1 6 6 6 2 Protein of unknown function (DUF2722) Spore_III_AF PF09581.10 CDJ61403.1 - 0.098 12.7 0.1 0.098 12.7 0.1 3.9 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) PIG-U PF06728.13 CDJ61403.1 - 0.25 10.4 3.2 4 6.4 0.0 3.3 3 2 0 3 3 3 0 GPI transamidase subunit PIG-U Utp14 PF04615.13 CDJ61403.1 - 1.3 7.5 43.7 0.47 9.0 30.9 2.7 2 1 0 2 2 2 0 Utp14 protein CBFD_NFYB_HMF PF00808.23 CDJ61404.1 - 5e-07 29.9 0.2 1.1e-06 28.8 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2722 PF10846.8 CDJ61404.1 - 0.0021 17.1 4.2 0.0021 17.1 4.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SLM4 PF16818.5 CDJ61404.1 - 0.0049 16.9 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein SLM4 Histone PF00125.24 CDJ61404.1 - 0.005 17.2 0.1 0.005 17.2 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 CDJ61404.1 - 0.015 15.4 17.1 0.018 15.0 17.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 CDJ61404.1 - 0.023 13.5 0.1 0.034 13.0 0.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-T_C PF15511.6 CDJ61404.1 - 0.028 14.5 1.2 0.028 14.5 1.2 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Caudo_TAP PF02413.17 CDJ61404.1 - 0.31 11.2 11.1 0.59 10.3 11.1 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF4834 PF16118.5 CDJ61404.1 - 1 10.3 4.1 0.44 11.6 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RPN2_C PF18004.1 CDJ61404.1 - 1.9 8.4 8.3 36 4.2 0.0 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_23 PF13476.6 CDJ61405.1 - 0.0024 18.4 0.0 0.0024 18.4 0.0 4.8 2 1 2 4 4 4 1 AAA domain Caldesmon PF02029.15 CDJ61405.1 - 0.0029 16.4 25.6 0.0029 16.4 25.6 3.9 3 1 0 3 3 3 1 Caldesmon Apt1 PF10351.9 CDJ61405.1 - 0.0034 16.3 10.9 0.0034 16.3 10.9 5.2 3 2 2 5 5 5 1 Golgi-body localisation protein domain DDHD PF02862.17 CDJ61405.1 - 0.012 15.7 0.7 0.012 15.7 0.7 4.7 2 1 1 3 3 3 0 DDHD domain Utp14 PF04615.13 CDJ61405.1 - 0.37 9.3 67.4 0.2 10.2 25.2 3.3 3 0 0 3 3 3 0 Utp14 protein Chorion_3 PF05387.11 CDJ61406.1 - 0.29 10.8 3.4 0.35 10.5 3.4 1.1 1 0 0 1 1 1 0 Chorion family 3 SPT6_acidic PF14632.6 CDJ61407.1 - 3.4e-09 37.2 9.0 3.4e-09 37.2 9.0 9.6 8 2 3 11 11 11 1 Acidic N-terminal SPT6 Glt_symporter PF03616.14 CDJ61407.1 - 2.6 6.7 6.7 7.7 5.1 0.1 3.4 2 0 0 2 2 2 0 Sodium/glutamate symporter Pro_CA PF00484.19 CDJ61408.1 - 0.18 12.1 0.4 0.35 11.1 0.4 1.4 1 0 0 1 1 1 0 Carbonic anhydrase DUF2756 PF10956.8 CDJ61408.1 - 0.25 11.9 13.4 0.4 11.2 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) Lactamase_B_2 PF12706.7 CDJ61409.1 - 0.00061 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GTSE1_N PF15259.6 CDJ61409.1 - 0.12 12.5 4.3 1.6 8.9 3.2 2.1 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 SPX PF03105.19 CDJ61409.1 - 0.18 11.7 7.3 0.25 11.2 7.3 1.1 1 0 0 1 1 1 0 SPX domain LPD7 PF18821.1 CDJ61409.1 - 2.1 8.5 5.2 4 7.6 5.2 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 HEAT PF02985.22 CDJ61410.1 - 0.00028 20.9 7.3 0.14 12.5 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat CLASP_N PF12348.8 CDJ61410.1 - 0.0034 17.0 0.1 20 4.7 0.0 3.5 2 1 1 3 3 3 1 CLASP N terminal Condensin2nSMC PF12422.8 CDJ61410.1 - 0.011 15.9 0.0 0.96 9.6 0.0 2.8 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Dynein_AAA_lid PF17852.1 CDJ61410.1 - 0.02 15.0 0.2 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain Cohesin_HEAT PF12765.7 CDJ61410.1 - 0.069 13.5 0.2 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 CDJ61410.1 - 0.21 10.1 1.6 0.35 9.4 1.6 1.2 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_2 PF13646.6 CDJ61410.1 - 1.6 9.2 16.7 1.1 9.7 2.5 4.0 3 1 0 3 3 3 0 HEAT repeats Spt20 PF12090.8 CDJ61410.1 - 2.9 7.4 20.6 1.9 8.0 2.8 3.4 3 0 0 3 3 3 0 Spt20 family DUF2722 PF10846.8 CDJ61410.1 - 7.9 5.3 13.8 3.4 6.5 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) CAP PF00188.26 CDJ61411.1 - 2.2e-12 47.9 0.2 6.1e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 CDJ61411.1 - 0.0011 19.1 8.5 0.0011 19.1 8.5 3.4 3 0 0 3 3 3 1 Thrombospondin type 1 domain TFIIA PF03153.13 CDJ61414.1 - 0.052 13.5 23.8 0.067 13.2 23.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.13 CDJ61414.1 - 0.59 9.9 13.7 0.71 9.7 13.7 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SPX PF03105.19 CDJ61414.1 - 0.99 9.2 31.9 1.2 9.0 31.9 1.0 1 0 0 1 1 1 0 SPX domain MscS_TM PF12794.7 CDJ61414.1 - 1.4 7.7 3.2 1.6 7.5 3.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 NST1 PF13945.6 CDJ61414.1 - 1.7 8.7 26.1 2.4 8.2 26.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator SSP160 PF06933.11 CDJ61414.1 - 3.8 5.6 42.9 4.5 5.4 42.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4647 PF15504.6 CDJ61414.1 - 4 6.4 19.5 4.8 6.2 19.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SRP-alpha_N PF04086.13 CDJ61414.1 - 6 6.7 21.3 7 6.5 21.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TMEM51 PF15345.6 CDJ61414.1 - 9.5 6.0 20.2 12 5.7 20.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF202 PF02656.15 CDJ61415.1 - 2e-13 50.6 6.3 2e-13 50.6 6.3 5.7 5 1 0 5 5 5 1 Domain of unknown function (DUF202) VTC PF09359.10 CDJ61415.1 - 3.3e-06 26.7 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 VTC domain Serinc PF03348.15 CDJ61415.1 - 0.27 10.1 3.6 6 5.7 0.1 2.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) RIFIN PF02009.16 CDJ61415.1 - 3.2 7.6 19.2 0.29 11.0 3.1 2.7 2 0 0 2 2 2 0 Rifin DUF2722 PF10846.8 CDJ61416.1 - 0.0046 16.0 13.5 0.0046 16.0 13.5 6.6 3 1 1 4 4 4 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ61416.1 - 0.0059 16.3 7.4 0.0059 16.3 7.4 6.5 4 1 1 5 5 5 2 Spt20 family Erv26 PF04148.13 CDJ61416.1 - 0.23 11.3 0.0 0.23 11.3 0.0 3.1 3 1 0 3 3 3 0 Transmembrane adaptor Erv26 MOZART1 PF12554.8 CDJ61417.1 - 0.045 13.5 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Rep_fac_C PF08542.11 CDJ61418.1 - 1.3e-11 44.8 0.0 2.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DUF1481 PF07356.12 CDJ61420.1 - 0.095 12.5 2.5 0.13 12.0 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1481) Filament PF00038.21 CDJ61420.1 - 0.21 11.1 16.9 2.9 7.4 16.9 2.0 1 1 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.15 CDJ61420.1 - 2.8 7.4 9.2 3.9 7.0 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CHDCT2 PF08074.11 CDJ61420.1 - 3.3 7.9 8.5 48 4.1 8.5 2.0 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain DUF3584 PF12128.8 CDJ61420.1 - 3.7 4.9 18.2 8.9 3.7 18.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CLZ PF16526.5 CDJ61420.1 - 5.1 7.5 14.0 0.11 12.8 2.0 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cation_efflux PF01545.21 CDJ61421.1 - 3.8e-45 154.1 8.2 6.3e-45 153.4 8.2 1.4 1 0 0 1 1 1 1 Cation efflux family DUF1180 PF06679.12 CDJ61421.1 - 1.3 9.4 10.4 0.72 10.2 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DA1-like PF12315.8 CDJ61423.1 - 1.6e-07 30.9 3.0 1.6e-07 30.9 3.0 3.5 3 1 0 3 3 3 1 Protein DA1 UQ_con PF00179.26 CDJ61425.1 - 2.9e-15 56.2 0.0 4.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDJ61425.1 - 0.079 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Vps36-NZF-N PF16988.5 CDJ61425.1 - 0.09 12.2 0.2 0.21 11.0 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Reticulon PF02453.17 CDJ61426.1 - 3.4e-11 43.3 7.1 4.8e-11 42.9 6.9 1.3 1 1 0 1 1 1 1 Reticulon SNF2_N PF00176.23 CDJ61427.1 - 7.4e-38 130.2 0.2 7.1e-24 84.2 0.0 3.4 3 0 0 3 3 3 3 SNF2 family N-terminal domain zf-PARP PF00645.18 CDJ61427.1 - 1.7e-06 28.8 0.1 8.9e-06 26.5 0.1 2.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DEAD PF00270.29 CDJ61427.1 - 0.00062 19.6 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase PyrI_C PF02748.15 CDJ61427.1 - 0.061 13.2 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3800 PF12686.7 CDJ61429.1 - 4.5 7.9 9.4 3e+02 2.1 0.1 4.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Herpes_UL33 PF03581.13 CDJ61429.1 - 5.6 7.4 5.5 6.9 7.1 0.2 3.5 2 0 0 2 2 2 0 Herpesvirus UL33-like protein ATP-synt_E PF05680.12 CDJ61430.1 - 0.27 11.6 1.2 5.2 7.5 1.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain Radial_spoke_3 PF06098.11 CDJ61431.1 - 5e-15 55.5 6.7 5e-15 55.5 6.7 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 TRM13 PF05206.14 CDJ61432.1 - 9.1e-24 84.4 4.2 7.5e-10 38.8 4.5 4.1 3 1 1 4 4 4 3 Methyltransferase TRM13 zf-U11-48K PF05253.12 CDJ61432.1 - 6.9e-05 22.7 0.2 0.00015 21.6 0.2 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 CDJ61432.1 - 0.011 15.8 0.1 0.41 10.6 0.1 2.9 2 0 0 2 2 2 0 Methyltransferase domain FTR PF01913.18 CDJ61432.1 - 0.12 12.3 1.9 0.43 10.5 0.3 2.5 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase CwfJ_C_2 PF04676.14 CDJ61433.1 - 2.1e-18 67.0 0.0 2.1e-18 67.0 0.0 2.7 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CDJ61433.1 - 1.8e-15 56.9 0.0 3.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Styelin PF17562.2 CDJ61433.1 - 0.13 12.6 0.6 0.93 9.9 0.2 2.5 2 0 0 2 2 2 0 Styelin Bax1-I PF01027.20 CDJ61434.1 - 8.8e-31 107.4 21.9 1e-30 107.1 21.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1754 PF08555.10 CDJ61436.1 - 0.00068 20.4 15.8 0.09 13.6 4.1 2.4 1 1 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Sld5 PF05916.11 CDJ61436.1 - 0.068 13.6 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 GINS complex protein PilJ PF13675.6 CDJ61436.1 - 0.16 12.0 2.9 0.23 11.5 0.4 2.4 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sigma70_ner PF04546.13 CDJ61436.1 - 0.31 10.9 9.7 0.023 14.6 2.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Menin PF05053.13 CDJ61436.1 - 2.9 6.2 8.5 3.4 5.9 8.5 1.1 1 0 0 1 1 1 0 Menin FAM176 PF14851.6 CDJ61436.1 - 5.5 6.6 7.2 3.6 7.2 3.8 2.0 2 0 0 2 2 2 0 FAM176 family tRNA_bind_2 PF13725.6 CDJ61436.1 - 8.1 6.1 7.8 0.65 9.6 0.4 2.4 2 1 1 3 3 3 0 Possible tRNA binding domain CDPS PF16715.5 CDJ61437.1 - 0.014 15.1 3.9 0.059 13.0 0.2 2.2 2 0 0 2 2 2 0 Cyclodipeptide synthase BAR PF03114.18 CDJ61437.1 - 0.025 14.3 3.5 0.028 14.0 0.8 2.2 2 0 0 2 2 2 0 BAR domain ISG65-75 PF11727.8 CDJ61437.1 - 1 8.5 7.6 0.13 11.5 0.7 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein RAP PF08373.10 CDJ61438.1 - 6.3e-17 61.4 0.0 1e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 CDJ61438.1 - 0.0023 18.1 0.1 0.0023 18.1 0.1 1.8 2 0 0 2 2 2 1 REase_MTES_1575 zf-RING_5 PF14634.6 CDJ61439.1 - 0.011 15.6 7.2 0.011 15.6 7.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain PAT1 PF09770.9 CDJ61439.1 - 4.2 5.5 43.4 5.6 5.1 43.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltrans_RNA PF04452.14 CDJ61441.1 - 4.8e-32 111.1 0.0 1.6e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase AbiEi_3 PF11459.8 CDJ61441.1 - 0.0037 17.0 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DUF3328 PF11807.8 CDJ61442.1 - 0.33 10.7 3.7 0.87 9.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF1600 PF07667.11 CDJ61442.1 - 0.36 11.1 3.4 0.8 9.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) E1-E2_ATPase PF00122.20 CDJ61443.1 - 3.8e-51 173.2 2.7 7.5e-50 169.0 0.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDJ61443.1 - 2e-38 131.9 0.3 2.1e-32 112.3 0.0 2.7 1 1 1 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDJ61443.1 - 5.9e-21 75.7 2.3 6e-18 65.9 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDJ61443.1 - 1.4e-20 72.8 0.1 6.9e-20 70.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDJ61443.1 - 2.2e-19 69.3 0.0 4.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDJ61443.1 - 8.3e-06 25.7 0.6 7.3e-05 22.6 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ61443.1 - 0.0017 18.8 0.0 0.0086 16.5 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDJ61443.1 - 0.17 12.0 0.0 0.59 10.3 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase OAD_gamma PF04277.13 CDJ61444.1 - 1.9 9.2 0.0 1.9 9.2 0.0 3.2 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Spt20 PF12090.8 CDJ61444.1 - 2.3 7.8 7.7 0.58 9.7 4.7 1.5 2 0 0 2 2 2 0 Spt20 family Laminin_G_3 PF13385.6 CDJ61445.1 - 6.9e-05 23.0 0.0 0.0034 17.5 0.0 2.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4179 PF13786.6 CDJ61447.1 - 0.09 13.3 0.9 42 4.7 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 CDJ61448.1 - 0.0026 17.4 33.8 0.0032 17.1 33.8 1.1 1 0 0 1 1 1 1 Spt20 family DUF3959 PF13105.6 CDJ61448.1 - 0.065 12.7 2.5 0.076 12.5 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Lin-8 PF03353.15 CDJ61448.1 - 0.22 11.1 23.6 0.26 10.8 23.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MRI PF15325.6 CDJ61448.1 - 0.4 11.8 13.9 0.12 13.5 3.0 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection TFIIA PF03153.13 CDJ61448.1 - 0.42 10.6 31.0 0.49 10.3 31.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MPM1 PF17234.2 CDJ61448.1 - 0.7 10.1 15.1 0.87 9.8 15.1 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SCIMP PF15050.6 CDJ61448.1 - 1.2 9.6 7.3 1.7 9.1 7.3 1.3 1 0 0 1 1 1 0 SCIMP protein Macoilin PF09726.9 CDJ61448.1 - 2.3 6.7 20.1 2.8 6.4 20.1 1.1 1 0 0 1 1 1 0 Macoilin family TetR_C_1 PF02909.17 CDJ61448.1 - 2.9 7.7 6.0 5.4 6.8 6.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Het-C PF07217.11 CDJ61448.1 - 3 6.3 11.7 3.7 6.0 11.7 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Miga PF10265.9 CDJ61448.1 - 3.1 6.7 15.2 3.6 6.4 15.2 1.1 1 0 0 1 1 1 0 Mitoguardin PA26 PF04636.13 CDJ61448.1 - 3.6 6.4 12.7 4.3 6.2 12.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1043 PF06295.12 CDJ61448.1 - 4 7.5 22.8 5.3 7.1 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Gastrin PF00918.17 CDJ61448.1 - 4.2 8.4 14.7 5.2 8.0 14.7 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family GREB1 PF15782.5 CDJ61448.1 - 6.9 3.6 23.1 7.9 3.5 23.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 CDJ61448.1 - 9.1 5.8 35.1 0.22 11.1 8.7 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 CDJ61448.1 - 9.2 5.5 13.5 11 5.3 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.8 CDJ61451.1 - 0.74 10.3 9.1 0.45 11.0 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spt20 PF12090.8 CDJ61451.1 - 6.4 6.3 24.3 0.15 11.6 13.4 2.6 3 0 0 3 3 3 0 Spt20 family Cwf_Cwc_15 PF04889.12 CDJ61454.1 - 0.0028 17.5 4.4 0.0034 17.2 4.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MMR1 PF08505.10 CDJ61454.1 - 0.013 15.8 14.2 0.016 15.5 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PEX11 PF05648.14 CDJ61454.1 - 0.024 14.1 2.2 0.034 13.6 2.2 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) SR-25 PF10500.9 CDJ61454.1 - 0.041 13.5 12.1 0.07 12.7 12.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIP5K PF01504.18 CDJ61454.1 - 0.082 12.1 5.7 0.1 11.8 5.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SMYLE_N PF18615.1 CDJ61454.1 - 0.25 10.8 9.6 0.29 10.6 9.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4820 PF16091.5 CDJ61454.1 - 0.28 10.5 15.1 0.25 10.7 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) TFIIA PF03153.13 CDJ61454.1 - 0.33 10.9 28.6 0.42 10.6 28.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP2 PF01569.21 CDJ61454.1 - 0.4 10.4 3.3 7.7 6.3 0.7 2.1 1 1 1 2 2 2 0 PAP2 superfamily DUF1501 PF07394.12 CDJ61454.1 - 1 8.3 13.5 1.2 8.2 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RIFIN PF02009.16 CDJ61454.1 - 1.5 8.7 11.2 1.9 8.3 11.2 1.1 1 0 0 1 1 1 0 Rifin Hid1 PF12722.7 CDJ61454.1 - 2.9 5.9 12.9 3.4 5.7 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bud13 PF09736.9 CDJ61454.1 - 3 8.3 11.8 4.3 7.7 11.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Spc7_N PF15402.6 CDJ61454.1 - 3.7 5.7 16.9 4.1 5.5 16.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Med15 PF09606.10 CDJ61454.1 - 4.5 5.9 27.4 5.2 5.6 27.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 CDJ61454.1 - 7.9 6.5 8.9 11 6.0 8.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 CDJ61454.1 - 9.8 4.3 22.1 11 4.2 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNB PF00773.19 CDJ61455.1 - 1.6e-32 113.1 6.4 8.7e-29 100.9 2.1 3.4 1 1 1 2 2 2 2 RNB domain SUIM_assoc PF16619.5 CDJ61455.1 - 0.0097 15.9 3.4 0.0097 15.9 3.4 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Macoilin PF09726.9 CDJ61455.1 - 0.013 14.1 11.8 0.016 13.8 11.8 1.1 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 CDJ61455.1 - 0.051 11.6 4.3 0.067 11.2 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MMR1 PF08505.10 CDJ61455.1 - 0.057 13.7 13.3 0.088 13.1 13.3 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GREB1 PF15782.5 CDJ61455.1 - 0.13 9.3 12.1 0.16 9.0 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BAF1_ABF1 PF04684.13 CDJ61455.1 - 0.2 10.7 21.7 0.28 10.2 21.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 CDJ61455.1 - 0.23 10.2 11.9 0.33 9.7 11.9 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ61455.1 - 0.24 10.4 10.5 0.33 9.9 10.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CDJ61455.1 - 0.31 10.2 5.2 0.5 9.5 5.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Asp-B-Hydro_N PF05279.11 CDJ61455.1 - 0.64 10.0 8.1 0.95 9.5 8.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PNISR PF15996.5 CDJ61455.1 - 1 9.6 15.1 1.5 9.1 15.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAPS PF04499.15 CDJ61455.1 - 2 7.1 14.6 2.8 6.6 14.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Suf PF05843.14 CDJ61455.1 - 2 8.3 11.0 22 4.9 12.2 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF755 PF05501.11 CDJ61455.1 - 2.3 8.5 25.4 2.2 8.6 12.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Peptidase_S64 PF08192.11 CDJ61455.1 - 2.3 6.6 11.8 3 6.2 11.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 CDJ61455.1 - 2.7 7.5 13.9 4.5 6.7 13.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ALMT PF11744.8 CDJ61455.1 - 5 5.8 7.7 8 5.2 7.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MFS_1 PF07690.16 CDJ61456.1 - 9.7e-11 41.2 0.3 9.7e-11 41.2 0.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ61456.1 - 0.0017 17.3 0.1 0.0017 17.3 0.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter LptF_LptG PF03739.14 CDJ61456.1 - 0.51 9.1 11.3 0.99 8.2 11.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CNDH2_C PF16858.5 CDJ61456.1 - 2.5 7.9 36.3 2.2 8.1 30.4 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vac7 PF12751.7 CDJ61456.1 - 2.8 7.3 18.7 0.097 12.1 12.9 1.5 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 CRT10 PF08728.10 CDJ61456.1 - 9.1 4.3 15.3 12 3.9 15.3 1.1 1 0 0 1 1 1 0 CRT10 GREB1 PF15782.5 CDJ61456.1 - 9.5 3.2 35.6 16 2.5 35.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S8 PF00082.22 CDJ61457.1 - 4.4e-21 75.4 0.0 4.4e-21 75.4 0.0 3.0 2 2 1 3 3 3 1 Subtilase family KOW PF00467.29 CDJ61457.1 - 2.6e-05 24.0 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 KOW motif SUIM_assoc PF16619.5 CDJ61457.1 - 0.007 16.4 0.8 0.018 15.1 0.8 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RLL PF10036.9 CDJ61457.1 - 0.044 13.6 3.3 0.088 12.6 3.3 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein SAP130_C PF16014.5 CDJ61457.1 - 1.8 7.6 19.3 3.2 6.8 19.3 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Mucin PF01456.17 CDJ61458.1 - 0.02 14.9 5.6 0.029 14.4 5.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HECT PF00632.25 CDJ61460.1 - 2.2e-52 178.5 0.0 4.6e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) YppG PF14179.6 CDJ61460.1 - 0.018 15.7 0.6 0.018 15.7 0.6 6.5 7 0 0 7 7 7 0 YppG-like protein DEAD PF00270.29 CDJ61461.1 - 1.1e-05 25.3 0.2 0.0079 16.0 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Cas_NE0113 PF09623.10 CDJ61461.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Viral_helicase1 PF01443.18 CDJ61461.1 - 0.022 14.5 0.3 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 CDJ61461.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDJ61461.1 - 0.031 14.5 0.5 0.21 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDJ61461.1 - 0.91 10.0 0.1 0.91 10.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 CDJ61463.1 - 7.1 6.5 16.8 9.2 6.1 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_7N PF13733.6 CDJ61464.1 - 0.13 11.9 3.4 0.45 10.2 3.4 2.0 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Sedlin_N PF04628.13 CDJ61466.1 - 8.5e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SR-25 PF10500.9 CDJ61466.1 - 0.061 12.9 21.5 0.08 12.5 21.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 CDJ61466.1 - 0.45 10.4 3.4 0.57 10.0 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF515 PF04415.12 CDJ61466.1 - 3.5 5.9 11.2 3.9 5.8 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 CDJ61468.1 - 2.6 7.6 10.5 3.7 7.1 10.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ61469.1 - 0.00098 19.5 6.3 0.0013 19.0 6.3 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4799 PF16056.5 CDJ61469.1 - 0.0037 16.5 7.0 0.0052 16.0 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) TFIIA PF03153.13 CDJ61469.1 - 0.0069 16.4 25.4 0.0087 16.1 25.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAT PF03417.16 CDJ61469.1 - 0.039 13.7 3.2 0.054 13.2 3.2 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SR-25 PF10500.9 CDJ61469.1 - 0.076 12.6 16.3 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SMI1_KNR4 PF09346.10 CDJ61469.1 - 0.078 13.4 1.2 1.5 9.2 0.1 2.1 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) BAF1_ABF1 PF04684.13 CDJ61469.1 - 0.09 11.8 9.5 0.13 11.3 9.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 CDJ61469.1 - 0.099 12.8 13.3 0.14 12.3 13.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF1635 PF07795.11 CDJ61469.1 - 0.69 9.7 19.8 2.6 7.8 10.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) OmpH PF03938.14 CDJ61469.1 - 0.8 10.0 20.5 1.2 9.5 20.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prok-TraM PF09228.10 CDJ61469.1 - 1.2 9.6 12.7 0.12 12.7 8.5 1.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Roughex PF06020.11 CDJ61469.1 - 1.8 7.6 7.5 2.5 7.1 7.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF2232 PF09991.9 CDJ61469.1 - 2.4 7.3 3.5 3.2 6.8 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) AIF_C PF14721.6 CDJ61469.1 - 3.1 8.1 8.1 1.8 8.9 3.9 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.15 CDJ61469.1 - 3.7 6.4 6.0 4.6 6.1 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FliP PF00813.20 CDJ61469.1 - 3.9 7.3 5.2 5.7 6.8 5.2 1.2 1 0 0 1 1 1 0 FliP family NEMP PF10225.9 CDJ61469.1 - 4.2 7.0 8.3 0.14 11.8 2.4 1.4 2 0 0 2 2 2 0 NEMP family Phostensin_N PF13916.6 CDJ61469.1 - 4.4 7.7 20.6 23 5.4 7.6 3.0 1 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal NUC153 PF08159.12 CDJ61470.1 - 4.4e-07 29.6 12.6 8.2e-06 25.5 1.8 3.0 3 0 0 3 3 3 2 NUC153 domain TFIIA PF03153.13 CDJ61470.1 - 0.0025 17.9 24.7 0.0025 17.9 24.7 4.7 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ61470.1 - 0.061 13.6 0.4 0.061 13.6 0.4 7.3 5 1 2 7 7 7 0 Anti-sigma-K factor rskA Sporozoite_P67 PF05642.11 CDJ61471.1 - 0.01 14.0 1.0 0.01 14.0 1.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CDJ61471.1 - 0.094 12.3 12.5 0.098 12.3 12.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CDJ61471.1 - 0.88 7.6 11.9 0.9 7.5 11.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RskA PF10099.9 CDJ61472.1 - 4.8e-05 23.7 11.2 0.0074 16.6 10.6 5.3 1 1 4 5 5 5 3 Anti-sigma-K factor rskA DUF2379 PF09543.10 CDJ61473.1 - 0.018 15.2 2.5 0.058 13.6 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) RNA_pol PF00940.19 CDJ61474.1 - 4e-136 454.1 0.0 1.3e-135 452.5 0.0 2.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDJ61474.1 - 3.5e-13 49.7 46.6 3.3e-09 36.6 0.2 6.2 4 2 1 5 5 5 3 DNA-directed RNA polymerase N-terminal YgbB PF02542.16 CDJ61475.1 - 1e-47 162.3 1.6 4e-42 144.1 0.6 2.4 2 0 0 2 2 2 2 YgbB family TPR_7 PF13176.6 CDJ61476.1 - 0.1 12.6 0.6 0.58 10.3 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat BCAS2 PF05700.11 CDJ61477.1 - 3e-28 99.0 4.4 3e-28 99.0 4.4 1.4 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 CDJ61477.1 - 0.0074 16.5 3.6 0.01 16.0 3.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding LETM1 PF07766.13 CDJ61477.1 - 0.019 14.3 0.1 0.032 13.6 0.1 1.3 1 1 0 1 1 1 0 LETM1-like protein HAUS6_N PF14661.6 CDJ61477.1 - 0.14 11.8 4.7 0.26 10.9 4.7 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_M20 PF01546.28 CDJ61478.1 - 9.5e-09 35.3 0.1 1.1e-07 31.8 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 PRK PF00485.18 CDJ61479.1 - 0.00052 19.8 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 CDJ61479.1 - 0.0037 17.7 0.0 0.014 15.8 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDJ61479.1 - 0.0049 17.4 0.6 0.006 17.1 0.6 1.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 CDJ61479.1 - 0.01 15.8 0.2 0.053 13.4 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CDJ61479.1 - 0.01 15.8 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 CDJ61479.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CDJ61479.1 - 0.014 15.9 0.6 0.03 14.8 0.6 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CDJ61479.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDJ61479.1 - 0.017 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CDJ61479.1 - 0.017 15.4 0.3 0.025 14.9 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDJ61479.1 - 0.02 15.1 0.3 0.033 14.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDJ61479.1 - 0.033 14.7 0.8 0.053 14.0 0.8 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDJ61479.1 - 0.053 13.9 0.1 0.12 12.8 0.1 1.7 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 CDJ61479.1 - 0.054 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 CDJ61479.1 - 0.056 12.4 0.0 0.12 11.3 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CDJ61479.1 - 0.086 12.0 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 CDJ61479.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 CDJ61479.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CDJ61479.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDJ61479.1 - 0.18 11.7 0.4 0.38 10.7 0.4 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CDJ61479.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CDJ61479.1 - 0.26 10.8 0.3 0.42 10.2 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CoaE PF01121.20 CDJ61479.1 - 0.36 10.5 1.2 0.51 10.0 1.2 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Ribosomal_L16 PF00252.18 CDJ61480.1 - 3.9e-37 127.2 0.0 4.8e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e GP40 PF11025.8 CDJ61481.1 - 0.074 12.8 1.1 0.15 11.8 1.1 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Macoilin PF09726.9 CDJ61482.1 - 9.7 4.6 30.0 1.3 7.5 15.1 2.7 2 1 0 2 2 2 0 Macoilin family PNISR PF15996.5 CDJ61483.1 - 0.92 9.8 57.6 1 9.6 32.7 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR ANAPC_CDC26 PF10471.9 CDJ61484.1 - 0.04 14.8 20.5 0.04 14.8 20.5 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Pex14_N PF04695.13 CDJ61484.1 - 0.12 13.0 29.1 0.33 11.6 6.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 CDJ61484.1 - 1.6 8.5 12.4 0.71 9.6 3.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ61484.1 - 1.7 8.4 15.5 0.71 9.6 5.9 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Apt1 PF10351.9 CDJ61484.1 - 3 6.6 17.3 2.2 7.1 6.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4228 PF14009.6 CDJ61484.1 - 3.9 7.8 13.0 4 7.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) EBP50_C PF09007.11 CDJ61484.1 - 6.2 7.8 26.0 8.6 7.4 5.5 2.2 2 0 0 2 2 2 0 EBP50, C-terminal Calici_coat_C PF08435.11 CDJ61484.1 - 6.7 6.2 10.6 0.21 11.1 3.2 2.0 2 1 0 2 2 2 0 Calicivirus coat protein C-terminal V_ATPase_I PF01496.19 CDJ61484.1 - 9.3 4.0 11.6 0.11 10.4 4.5 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMEM119 PF15724.5 CDJ61487.1 - 0.66 10.0 8.6 0.78 9.7 8.6 1.2 1 0 0 1 1 1 0 TMEM119 family DUF5523 PF17661.1 CDJ61487.1 - 7.4 6.2 11.6 8.9 5.9 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TFIIA PF03153.13 CDJ61488.1 - 7e-05 23.0 37.2 0.0052 16.8 9.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 CDJ61488.1 - 0.00076 19.5 6.5 0.069 13.1 0.0 2.2 2 0 0 2 2 2 1 Velvet factor SpoIIP PF07454.11 CDJ61488.1 - 0.0013 18.2 8.4 0.19 11.2 0.2 2.2 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CDJ61488.1 - 0.0036 17.6 2.3 0.0036 17.6 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4770) Suf PF05843.14 CDJ61488.1 - 0.016 15.3 17.9 0.2 11.6 0.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Adeno_PIX PF03955.14 CDJ61488.1 - 0.016 15.4 1.0 0.016 15.4 1.0 2.8 3 0 0 3 3 2 0 Adenovirus hexon-associated protein (IX) Med15 PF09606.10 CDJ61488.1 - 0.054 12.2 36.3 0.068 11.8 16.6 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peroxin-13_N PF04088.13 CDJ61488.1 - 0.061 13.6 6.4 2.4 8.4 0.4 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CPSF100_C PF13299.6 CDJ61488.1 - 0.07 13.3 9.4 1.1 9.5 0.9 2.7 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CDJ61488.1 - 0.11 11.4 6.6 0.51 9.3 1.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GET2 PF08690.10 CDJ61488.1 - 0.19 11.3 19.5 0.081 12.6 6.0 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 G0-G1_switch_2 PF15103.6 CDJ61488.1 - 0.43 11.0 11.4 0.36 11.3 1.3 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 DDHD PF02862.17 CDJ61488.1 - 0.47 10.6 20.1 0.056 13.6 3.2 2.3 1 1 1 2 2 2 0 DDHD domain DUF3464 PF11947.8 CDJ61488.1 - 0.53 10.0 12.0 5.2 6.8 6.3 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 BSMAP PF12280.8 CDJ61488.1 - 0.63 10.2 10.2 3 8.0 1.3 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein Band_3_cyto PF07565.13 CDJ61488.1 - 0.67 9.7 11.7 2.6 7.8 2.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM176 PF14851.6 CDJ61488.1 - 0.73 9.5 8.2 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 FAM176 family MecA PF05389.12 CDJ61488.1 - 0.84 9.2 8.6 0.45 10.1 0.9 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) AIF_C PF14721.6 CDJ61488.1 - 1.1 9.6 12.5 2.5 8.5 1.7 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BORG_CEP PF14957.6 CDJ61488.1 - 1.1 10.4 9.8 3.7 8.7 1.0 2.6 2 0 0 2 2 2 0 Cdc42 effector MCU PF04678.13 CDJ61488.1 - 1.2 9.2 9.8 2.7 8.1 1.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Peptidase_S49_N PF08496.10 CDJ61488.1 - 1.4 8.9 8.6 1.6 8.8 1.4 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TCP PF03634.13 CDJ61488.1 - 1.5 9.3 17.1 2 9.0 1.7 2.6 3 0 0 3 3 2 0 TCP family transcription factor FAM60A PF15396.6 CDJ61488.1 - 1.7 8.6 12.9 1.8 8.6 2.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Connexin PF00029.19 CDJ61488.1 - 1.7 8.3 9.6 3.1 7.5 1.0 2.2 2 0 0 2 2 2 0 Connexin Tim54 PF11711.8 CDJ61488.1 - 1.8 7.3 12.0 0.9 8.3 1.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Miga PF10265.9 CDJ61488.1 - 2.3 7.1 8.8 0.59 9.0 1.1 2.0 2 0 0 2 2 2 0 Mitoguardin Rrp15p PF07890.12 CDJ61488.1 - 2.5 8.4 16.6 6.1 7.2 6.0 2.4 2 0 0 2 2 2 0 Rrp15p Hydin_ADK PF17213.3 CDJ61488.1 - 2.5 8.3 12.2 6.7 6.9 2.4 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF5327 PF17261.2 CDJ61488.1 - 2.5 8.9 26.2 1.6 9.5 8.8 2.7 3 0 0 3 3 2 0 Family of unknown function (DUF5327) RPA43_OB PF17875.1 CDJ61488.1 - 2.5 8.7 10.7 2 9.0 0.8 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Rxt3 PF08642.10 CDJ61488.1 - 2.8 8.7 7.6 2.8 8.7 0.5 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 GEN1_C PF18380.1 CDJ61488.1 - 3 8.8 10.6 4.6 8.2 1.1 2.8 3 0 0 3 3 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF5523 PF17661.1 CDJ61488.1 - 3.1 7.4 15.7 4.5 6.9 3.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) MAT1 PF06391.13 CDJ61488.1 - 3.1 7.6 22.8 5.3 6.8 5.5 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PA26 PF04636.13 CDJ61488.1 - 3.8 6.3 12.2 0.73 8.7 2.2 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) eIF-3_zeta PF05091.12 CDJ61488.1 - 4.2 6.2 21.0 2.9 6.7 8.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YABBY PF04690.13 CDJ61488.1 - 4.8 7.7 11.2 5.9 7.4 1.3 2.2 2 0 0 2 2 2 0 YABBY protein NifQ PF04891.12 CDJ61488.1 - 4.9 7.5 9.3 3.5 8.0 2.6 2.3 2 0 0 2 2 2 0 NifQ OATP PF03137.20 CDJ61488.1 - 5.5 5.1 7.0 4.1 5.6 2.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.15 CDJ61488.1 - 5.9 5.7 10.1 2.4 7.0 1.9 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Spt20 PF12090.8 CDJ61488.1 - 6.5 6.3 61.3 5.9 6.4 31.9 2.3 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 CDJ61488.1 - 6.6 7.1 20.9 2.3 8.6 5.2 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like U3_snoRNA_assoc PF08297.11 CDJ61488.1 - 7.4 7.3 12.9 1.1 10.0 1.9 2.6 3 0 0 3 3 2 0 U3 snoRNA associated Folate_carrier PF01770.18 CDJ61488.1 - 7.7 5.1 8.0 3.3 6.4 0.7 2.1 2 0 0 2 2 2 0 Reduced folate carrier EIIBC-GUT_N PF03612.14 CDJ61488.1 - 8 6.2 15.2 0.77 9.5 2.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 CDJ61488.1 - 8.6 5.0 23.2 18 3.9 23.2 1.4 1 1 0 1 1 1 0 Presenilin DUF3371 PF11851.8 CDJ61488.1 - 8.7 7.5 20.8 9.2 7.4 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RR_TM4-6 PF06459.12 CDJ61488.1 - 9.5 5.9 16.7 8.1 6.2 3.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TIMELESS PF04821.14 CDJ61488.1 - 9.9 5.3 15.3 4.1 6.6 2.9 2.1 2 0 0 2 2 2 0 Timeless protein US6 PF17616.2 CDJ61489.1 - 0.34 10.9 0.9 0.46 10.4 0.9 1.2 1 0 0 1 1 1 0 Viral unique short region 6 GerA PF03323.13 CDJ61489.1 - 2.6 6.4 7.8 5 5.5 6.6 1.8 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein RVT_1 PF00078.27 CDJ61490.1 - 9.6e-26 90.7 0.0 1.6e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CDJ61491.1 - 9.8e-07 29.4 0.3 1.5e-06 28.8 0.3 1.4 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase SSP160 PF06933.11 CDJ61493.1 - 0.016 13.5 14.3 0.021 13.0 14.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 CDJ61493.1 - 0.029 12.9 32.8 0.037 12.6 32.8 1.1 1 0 0 1 1 1 0 Macoilin family Connexin PF00029.19 CDJ61493.1 - 0.071 12.9 23.3 0.058 13.1 0.7 2.0 2 0 0 2 2 2 0 Connexin Peptidase_S64 PF08192.11 CDJ61493.1 - 0.26 9.7 28.0 0.32 9.4 28.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 LAP1C PF05609.12 CDJ61493.1 - 0.32 10.0 28.9 0.37 9.8 28.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4614 PF15391.6 CDJ61493.1 - 0.34 10.9 37.2 0.041 13.9 12.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Spt20 PF12090.8 CDJ61493.1 - 0.79 9.3 64.1 0.27 10.8 15.8 2.2 2 0 0 2 2 2 0 Spt20 family Tim54 PF11711.8 CDJ61493.1 - 0.86 8.3 22.8 0.61 8.8 3.9 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 EFTUD2 PF16004.5 CDJ61493.1 - 0.97 10.0 26.3 1.4 9.5 12.5 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Sec62 PF03839.16 CDJ61493.1 - 1.4 8.4 21.4 0.35 10.4 0.7 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Rxt3 PF08642.10 CDJ61493.1 - 2.1 9.1 17.3 3.7 8.3 1.1 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 SPX PF03105.19 CDJ61493.1 - 2.6 7.9 35.5 4 7.2 35.5 1.2 1 0 0 1 1 1 0 SPX domain Spem1 PF15670.5 CDJ61493.1 - 4.7 6.7 36.7 0.88 9.1 19.3 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 DUF1764 PF08576.10 CDJ61493.1 - 5.6 7.9 22.7 9.3 7.2 4.3 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.9 CDJ61493.1 - 5.8 6.4 48.8 1.4 8.5 23.2 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3306 PF11748.8 CDJ61493.1 - 8.4 7.3 21.2 9.9 7.1 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) GEMIN8 PF15348.6 CDJ61493.1 - 9.6 6.4 38.7 5.5 7.2 8.1 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 SNARE PF05739.19 CDJ61494.1 - 0.054 13.5 1.2 0.12 12.4 1.2 1.6 1 0 0 1 1 1 0 SNARE domain SurA_N_3 PF13624.6 CDJ61494.1 - 1.9 8.3 13.7 1.2 8.9 9.8 2.4 2 2 1 3 3 3 0 SurA N-terminal domain HVSL PF09749.9 CDJ61495.1 - 4.2e-19 69.0 14.4 2.6e-18 66.4 10.1 2.2 1 1 0 2 2 2 2 Uncharacterised conserved protein ALP_N PF17989.1 CDJ61495.1 - 0.036 14.2 0.4 0.093 12.9 0.1 1.9 2 0 0 2 2 2 0 Actin like proteins N terminal domain Presenilin PF01080.17 CDJ61495.1 - 0.44 9.3 21.4 0.22 10.3 6.2 2.1 2 0 0 2 2 2 0 Presenilin Senescence_reg PF04520.13 CDJ61495.1 - 1.1 10.0 19.1 3.4 8.5 8.6 2.4 2 0 0 2 2 2 0 Senescence regulator PAT1 PF09770.9 CDJ61495.1 - 3.3 5.9 17.7 0.65 8.2 13.4 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 CDJ61495.1 - 5.4 4.8 21.5 9.1 4.0 21.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ELO PF01151.18 CDJ61496.1 - 4e-11 42.9 7.9 9.5e-11 41.7 7.9 1.6 1 0 0 1 1 1 1 GNS1/SUR4 family FA_desaturase PF00487.24 CDJ61496.1 - 9.4e-07 28.9 5.0 9.4e-07 28.9 5.0 4.1 3 1 1 5 5 5 1 Fatty acid desaturase F-box-like PF12937.7 CDJ61497.1 - 0.00012 21.9 0.7 0.00075 19.4 0.7 2.5 1 0 0 1 1 1 1 F-box-like 5_nucleotid_C PF02872.18 CDJ61498.1 - 9.9e-37 126.6 0.0 2.4e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CDJ61498.1 - 5.8e-06 27.0 0.5 5.1e-05 23.9 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RskA PF10099.9 CDJ61499.1 - 0.0098 16.2 0.0 0.0098 16.2 0.0 20.0 3 3 7 10 10 10 1 Anti-sigma-K factor rskA DUF4179 PF13786.6 CDJ61499.1 - 0.048 14.1 0.0 0.048 14.1 0.0 8.3 7 2 0 7 7 7 0 Domain of unknown function (DUF4179) Kelch_1 PF01344.25 CDJ61501.1 - 2.6e-08 33.3 0.0 1e-05 25.0 0.0 3.4 3 0 0 3 3 3 1 Kelch motif DUF4770 PF15994.5 CDJ61501.1 - 0.00081 19.7 0.9 0.0016 18.7 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) Kelch_6 PF13964.6 CDJ61501.1 - 0.00092 19.4 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDJ61501.1 - 0.0079 16.1 0.0 0.53 10.4 0.0 2.5 2 0 0 2 2 2 1 Kelch motif DUF5558 PF17713.1 CDJ61501.1 - 0.013 15.8 1.6 0.013 15.8 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Kelch_3 PF13415.6 CDJ61501.1 - 0.069 13.5 0.2 0.67 10.3 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Spt20 PF12090.8 CDJ61501.1 - 0.09 12.4 13.0 0.025 14.2 5.9 2.2 2 0 0 2 2 2 0 Spt20 family Pkinase PF00069.25 CDJ61502.1 - 3.2e-34 118.5 0.0 1.8e-21 76.7 0.0 4.7 4 2 1 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61502.1 - 3e-10 39.8 0.0 3e-10 39.8 0.0 4.4 4 1 0 5 5 5 2 Protein tyrosine kinase TFIIA PF03153.13 CDJ61502.1 - 0.0012 18.9 48.9 0.0012 18.9 48.9 4.5 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 CDJ61502.1 - 0.0012 17.9 3.2 0.0012 17.9 3.2 6.2 3 2 2 5 5 5 1 Protein of unknown function (DUF2722) HSP90 PF00183.18 CDJ61505.1 - 8.5e-21 74.4 8.3 8.7e-21 74.4 0.9 2.3 1 1 2 3 3 3 2 Hsp90 protein LPD39 PF18858.1 CDJ61505.1 - 0.00021 21.5 1.3 0.0031 17.6 1.3 2.0 1 1 0 1 1 1 1 Large polyvalent protein associated domain 39 FAM176 PF14851.6 CDJ61505.1 - 0.18 11.4 2.8 0.71 9.5 0.4 2.0 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 CDJ61505.1 - 0.21 11.8 10.4 0.29 11.4 10.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAGA_bind PF06217.12 CDJ61506.1 - 4.5 7.5 15.1 0.088 13.1 4.4 2.6 2 0 0 2 2 2 0 GAGA binding protein-like family CH_2 PF06294.11 CDJ61507.1 - 4e-18 65.3 0.2 1e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF3972 PF13118.6 CDJ61507.1 - 0.0097 16.3 2.8 0.019 15.4 2.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3972) CAMSAP_CH PF11971.8 CDJ61507.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain NRDE-2 PF08424.10 CDJ61507.1 - 0.047 12.8 0.5 0.07 12.2 0.5 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference MYO10_CC PF16735.5 CDJ61507.1 - 0.34 11.1 5.9 5.2 7.3 1.5 3.2 2 1 1 3 3 3 0 Unconventional myosin-X coiled coil domain DUF2357 PF09823.9 CDJ61508.1 - 0.055 12.7 1.3 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) Couple_hipA PF13657.6 CDJ61508.1 - 0.11 13.1 0.6 1.9 9.2 0.2 2.2 2 0 0 2 2 2 0 HipA N-terminal domain Spt20 PF12090.8 CDJ61508.1 - 0.9 9.1 11.4 1.2 8.7 11.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF384 PF04064.13 CDJ61509.1 - 0.054 13.4 0.1 0.25 11.2 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF384) GWT1 PF06423.12 CDJ61510.1 - 0.00053 20.1 3.9 0.95 9.6 0.0 3.6 3 1 0 3 3 3 3 GWT1 2OG-FeII_Oxy_2 PF13532.6 CDJ61512.1 - 5.4e-09 36.5 4.1 6.4e-08 33.0 0.1 3.4 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily AP3D1 PF06375.11 CDJ61512.1 - 0.32 11.2 9.9 0.43 10.8 0.3 3.5 4 0 0 4 4 4 0 AP-3 complex subunit delta-1 Eapp_C PF10238.9 CDJ61512.1 - 6.4 6.8 13.5 7 6.7 0.0 3.9 4 0 0 4 4 4 0 E2F-associated phosphoprotein SMN PF06003.12 CDJ61512.1 - 8.7 5.5 9.3 5 6.3 4.3 2.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) RCC1 PF00415.18 CDJ61513.1 - 2.6e-18 66.4 10.8 1.1e-06 29.1 0.4 5.8 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDJ61513.1 - 8.2e-07 28.7 14.2 0.058 13.2 2.5 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat SPX PF03105.19 CDJ61513.1 - 0.014 15.3 0.2 0.014 15.3 0.2 6.4 4 1 0 4 4 4 0 SPX domain RPOL_N PF14700.6 CDJ61513.1 - 1.3 8.3 33.6 0.3 10.4 7.1 4.5 4 0 0 4 4 4 0 DNA-directed RNA polymerase N-terminal MecA PF05389.12 CDJ61513.1 - 3 7.4 26.6 1.2 8.7 5.7 4.5 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) AUX_IAA PF02309.16 CDJ61514.1 - 0.64 9.8 5.4 0.43 10.4 2.8 2.1 2 1 1 3 3 3 0 AUX/IAA family EF_TS PF00889.19 CDJ61515.1 - 2.3e-29 102.5 5.5 1.3e-27 96.8 5.5 2.6 1 1 0 1 1 1 1 Elongation factor TS ADK PF00406.22 CDJ61516.1 - 9.2e-25 87.5 0.0 8.2e-14 52.0 0.0 3.0 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDJ61516.1 - 4.3e-18 66.0 0.0 1.8e-08 34.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain Hydin_ADK PF17213.3 CDJ61516.1 - 0.00053 20.3 0.2 1.1 9.5 0.0 3.3 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDJ61516.1 - 0.00069 20.2 0.0 0.022 15.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain RIIa PF02197.17 CDJ61516.1 - 0.001 18.7 0.1 0.0024 17.5 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5586 PF17824.1 CDJ61516.1 - 0.03 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) AAA_33 PF13671.6 CDJ61516.1 - 0.06 13.5 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDJ61516.1 - 0.099 12.9 0.7 0.63 10.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CDJ61516.1 - 0.12 12.1 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Spt20 PF12090.8 CDJ61517.1 - 0.0019 17.8 17.6 0.0019 17.8 17.6 3.1 3 0 0 3 3 3 1 Spt20 family SNF2_N PF00176.23 CDJ61517.1 - 0.0044 15.8 0.0 0.0044 15.8 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain FAM176 PF14851.6 CDJ61517.1 - 0.042 13.5 6.7 0.11 12.1 4.6 2.7 3 0 0 3 3 3 0 FAM176 family DUF2052 PF09747.9 CDJ61517.1 - 0.3 11.2 12.1 0.98 9.5 9.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) EPL1 PF10513.9 CDJ61517.1 - 9.1 6.6 14.1 1.4 9.3 5.2 3.5 4 0 0 4 4 4 0 Enhancer of polycomb-like SPX PF03105.19 CDJ61518.1 - 4.3e-05 23.6 14.2 0.00046 20.2 3.7 2.3 2 0 0 2 2 2 2 SPX domain DDHD PF02862.17 CDJ61518.1 - 0.0014 18.8 2.0 0.0014 18.8 2.0 2.9 2 1 0 2 2 1 1 DDHD domain Connexin PF00029.19 CDJ61518.1 - 0.0016 18.2 3.3 0.0016 18.2 3.3 1.8 2 0 0 2 2 2 1 Connexin RSRP PF17069.5 CDJ61518.1 - 0.0073 15.9 8.8 0.0073 15.9 8.8 3.5 3 0 0 3 3 3 1 Arginine/Serine-Rich protein 1 DUF4667 PF15700.5 CDJ61518.1 - 0.0096 16.1 22.9 0.039 14.1 0.8 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4667) Dynamin_N PF00350.23 CDJ61518.1 - 0.014 15.4 1.3 0.034 14.2 1.3 1.6 1 0 0 1 1 1 0 Dynamin family AP3D1 PF06375.11 CDJ61518.1 - 0.016 15.4 8.9 0.016 15.4 8.9 2.5 3 0 0 3 3 2 0 AP-3 complex subunit delta-1 SpoIIP PF07454.11 CDJ61518.1 - 0.039 13.4 13.4 0.01 15.3 8.5 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 CDJ61518.1 - 0.12 11.2 12.3 0.25 10.2 12.3 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt20 PF12090.8 CDJ61518.1 - 0.14 11.7 33.1 0.086 12.4 28.2 2.3 2 0 0 2 2 2 0 Spt20 family FAM76 PF16046.5 CDJ61518.1 - 0.15 11.4 16.0 0.33 10.3 9.1 2.3 2 0 0 2 2 2 0 FAM76 protein Peptidase_S49_N PF08496.10 CDJ61518.1 - 0.16 12.0 11.5 0.46 10.5 11.5 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal O-antigen_lig PF13425.6 CDJ61518.1 - 0.23 10.2 1.5 0.36 9.6 1.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SR-25 PF10500.9 CDJ61518.1 - 0.24 11.0 54.8 0.11 12.1 8.9 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4199 PF13858.6 CDJ61518.1 - 0.24 11.8 2.6 0.85 10.0 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TERB2 PF15101.6 CDJ61518.1 - 0.25 11.4 19.0 0.037 14.1 12.1 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Apt1 PF10351.9 CDJ61518.1 - 0.27 10.0 19.7 0.14 11.0 2.8 3.0 3 0 0 3 3 3 0 Golgi-body localisation protein domain CDC45 PF02724.14 CDJ61518.1 - 0.44 8.8 14.8 0.24 9.6 7.8 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA_23 PF13476.6 CDJ61518.1 - 0.47 10.9 13.8 0.91 10.0 13.8 1.4 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 CDJ61518.1 - 0.59 8.8 5.6 0.97 8.1 0.8 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF4471 PF14740.6 CDJ61518.1 - 0.6 9.3 6.9 0.24 10.6 4.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DAG_kinase_N PF14513.6 CDJ61518.1 - 1 9.5 16.7 0.4 10.9 6.9 2.8 3 0 0 3 3 2 0 Diacylglycerol kinase N-terminus NEMP PF10225.9 CDJ61518.1 - 1.1 8.9 4.4 3.1 7.4 4.4 1.7 1 0 0 1 1 1 0 NEMP family 60KD_IMP PF02096.20 CDJ61518.1 - 1.1 9.1 5.2 2 8.3 5.2 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4446 PF14584.6 CDJ61518.1 - 1.4 8.9 4.4 2.6 8.0 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Phage_Gp23 PF10669.9 CDJ61518.1 - 1.5 9.2 12.1 2.7 8.3 12.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) BUD22 PF09073.10 CDJ61518.1 - 1.8 7.8 30.5 0.18 11.1 5.5 3.0 3 0 0 3 3 3 0 BUD22 AAR2 PF05282.11 CDJ61518.1 - 2.7 7.3 10.5 0.52 9.7 2.8 2.4 2 0 0 2 2 2 0 AAR2 protein Endostatin PF06482.11 CDJ61518.1 - 2.7 7.4 14.6 0.81 9.1 9.0 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Rxt3 PF08642.10 CDJ61518.1 - 2.8 8.7 12.8 18 6.1 0.1 2.9 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 SID-1_RNA_chan PF13965.6 CDJ61518.1 - 3 6.1 9.7 0.36 9.2 4.3 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 CDJ61518.1 - 3.2 6.7 11.7 0.19 10.8 5.0 2.0 2 0 0 2 2 2 0 CLN3 protein RR_TM4-6 PF06459.12 CDJ61518.1 - 4.2 7.1 22.0 0.68 9.7 12.9 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CDJ61518.1 - 4.5 7.0 14.5 2.8 7.7 9.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CSG2 PF16965.5 CDJ61518.1 - 4.6 6.1 10.8 0.14 11.1 3.6 1.9 2 0 0 2 2 2 0 Ceramide synthase regulator FAM176 PF14851.6 CDJ61518.1 - 4.9 6.8 17.9 0.15 11.7 7.4 3.0 3 0 0 3 3 3 0 FAM176 family Lin-8 PF03353.15 CDJ61518.1 - 5.2 6.6 28.7 0.38 10.3 11.2 3.0 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist EMC3_TMCO1 PF01956.16 CDJ61518.1 - 5.9 6.6 7.8 9.8 5.9 7.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PPL5 PF18168.1 CDJ61518.1 - 6 6.1 15.7 0.23 10.7 8.0 2.1 2 0 0 2 2 2 0 Prim-pol family 5 DUF4614 PF15391.6 CDJ61518.1 - 6.6 6.7 33.0 0.84 9.6 7.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) DUF2232 PF09991.9 CDJ61518.1 - 6.7 5.8 6.1 1.1 8.3 1.4 2.1 2 1 0 2 2 1 0 Predicted membrane protein (DUF2232) Neur_chan_memb PF02932.16 CDJ61518.1 - 6.8 6.7 14.0 5.9 6.9 8.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.16 CDJ61518.1 - 8.5 5.8 12.3 7.9 5.9 9.8 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 N2227 PF07942.12 CDJ61520.1 - 3.2e-74 249.5 3.0 9.7e-44 149.6 0.0 2.9 2 1 1 3 3 3 2 N2227-like protein Methyltransf_11 PF08241.12 CDJ61520.1 - 0.24 12.1 0.0 0.24 12.1 0.0 3.6 4 2 1 5 5 5 0 Methyltransferase domain DUF572 PF04502.13 CDJ61520.1 - 0.31 10.6 38.5 0.059 13.0 23.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) SOBP PF15279.6 CDJ61520.1 - 0.41 11.2 33.8 0.068 13.8 18.9 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Hamartin PF04388.12 CDJ61520.1 - 1.4 7.5 39.7 2.1 6.9 39.7 1.2 1 0 0 1 1 1 0 Hamartin protein CDC45 PF02724.14 CDJ61520.1 - 1.8 6.8 38.9 0.48 8.7 26.5 2.1 2 0 0 2 2 2 0 CDC45-like protein XRN_M PF17846.1 CDJ61520.1 - 3.5 6.5 28.6 1.2 8.0 18.1 2.3 2 0 0 2 2 2 0 Xrn1 helical domain BAF1_ABF1 PF04684.13 CDJ61520.1 - 8.9 5.2 42.3 5.5 5.9 27.7 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SRP-alpha_N PF04086.13 CDJ61520.1 - 9.3 6.1 44.3 11 5.8 29.8 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 CDJ61520.1 - 9.4 6.0 45.1 8.8 6.1 29.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PI31_Prot_C PF08577.11 CDJ61521.1 - 1.6e-07 32.4 18.1 1.6e-07 32.4 18.1 3.7 4 1 0 4 4 4 1 PI31 proteasome regulator SUIM_assoc PF16619.5 CDJ61521.1 - 0.027 14.5 4.7 0.081 13.0 4.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF755 PF05501.11 CDJ61521.1 - 0.032 14.5 5.5 0.032 14.5 5.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Aminotran_1_2 PF00155.21 CDJ61521.1 - 0.11 11.7 0.5 0.18 10.9 0.5 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Spt20 PF12090.8 CDJ61521.1 - 0.23 11.0 5.2 0.33 10.5 5.2 1.1 1 0 0 1 1 1 0 Spt20 family PRP3 PF08572.10 CDJ61522.1 - 1.4e-46 159.1 18.0 1.4e-46 159.1 18.0 2.2 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CDJ61522.1 - 1.2e-21 77.3 0.1 1.2e-21 77.3 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) TFIIA PF03153.13 CDJ61523.1 - 0.001 19.2 33.5 0.001 19.2 33.5 3.2 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 CDJ61523.1 - 0.0055 17.0 6.4 0.0055 17.0 6.4 10.3 8 3 0 8 8 8 1 Domain of unknown function (DUF755) SUIM_assoc PF16619.5 CDJ61523.1 - 0.014 15.5 4.8 0.014 15.5 4.8 5.3 6 0 0 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 YqfD PF06898.11 CDJ61523.1 - 0.18 10.6 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD P21-Arc PF04062.14 CDJ61523.1 - 1.1 9.3 6.7 2.2 8.3 6.7 1.4 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit TetR_C_23 PF17931.1 CDJ61523.1 - 5.3 7.2 7.2 2.5 8.3 0.6 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SNF2_N PF00176.23 CDJ61525.1 - 9.9e-28 96.9 0.0 9.9e-28 96.9 0.0 4.1 2 1 0 2 2 1 1 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 CDJ61525.1 - 1.5e-06 28.1 5.6 1.5e-06 28.1 5.6 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDJ61525.1 - 8.9e-06 25.9 7.8 8.9e-06 25.9 7.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 CDJ61525.1 - 0.00025 20.9 9.8 0.0018 18.2 9.8 2.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDJ61525.1 - 0.00052 19.8 4.8 0.0031 17.3 4.8 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDJ61525.1 - 0.00073 19.2 1.8 0.00073 19.2 1.8 3.3 5 0 0 5 5 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDJ61525.1 - 0.0024 18.0 7.6 0.0024 18.0 7.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CDJ61525.1 - 0.0052 16.6 5.4 0.0052 16.6 5.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 CDJ61525.1 - 0.84 10.1 5.7 15 6.1 3.5 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CDJ61525.1 - 1 9.3 11.6 3.4 7.6 7.5 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDJ61525.1 - 3.1 7.7 22.4 0.008 16.0 9.9 3.3 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDJ61525.1 - 8.9 6.2 9.3 4.9 7.0 5.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Surface_antigen PF11054.8 CDJ61528.1 - 5.1e-24 85.3 0.6 5.7e-23 81.9 0.6 1.9 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.8 CDJ61529.1 - 1.3e-26 93.8 8.3 2.2e-25 89.8 8.3 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen TALPID3 PF15324.6 CDJ61529.1 - 0.029 12.1 2.1 0.034 11.8 2.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target FSH1 PF03959.13 CDJ61529.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Beach PF02138.18 CDJ61530.1 - 2.9e-55 187.6 0.0 2.3e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 CDJ61530.1 - 0.0005 20.8 0.7 0.0034 18.2 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat AKAP2_C PF15304.6 CDJ61531.1 - 0.0011 18.4 3.2 0.0013 18.1 3.2 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus MAT1 PF06391.13 CDJ61531.1 - 0.0074 16.1 4.5 0.011 15.6 4.5 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Macoilin PF09726.9 CDJ61531.1 - 0.032 12.8 9.5 0.044 12.4 9.5 1.2 1 0 0 1 1 1 0 Macoilin family ubiquitin PF00240.23 CDJ61533.1 - 7.1e-07 28.9 0.1 1.7e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDJ61533.1 - 4.2e-05 23.9 0.0 0.00022 21.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDJ61533.1 - 0.033 14.0 0.1 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 CDJ61533.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain UN_NPL4 PF11543.8 CDJ61533.1 - 0.16 12.5 0.0 0.2 12.1 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Activator_LAG-3 PF11498.8 CDJ61534.1 - 0.0026 16.8 4.9 0.0026 16.8 4.9 4.8 3 2 1 4 4 2 1 Transcriptional activator LAG-3 RskA PF10099.9 CDJ61534.1 - 0.018 15.3 1.4 0.018 15.3 1.4 7.9 2 2 2 4 4 2 0 Anti-sigma-K factor rskA DUF2052 PF09747.9 CDJ61534.1 - 0.05 13.7 60.2 0.18 11.9 1.8 3.4 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDJ61534.1 - 0.065 13.1 59.5 0.8 9.5 18.9 3.4 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CDJ61534.1 - 0.16 10.8 0.0 0.16 10.8 0.0 3.1 2 1 1 3 3 2 0 Golgi-body localisation protein domain Utp14 PF04615.13 CDJ61534.1 - 0.66 8.5 54.6 1.2 7.6 14.6 2.2 2 0 0 2 2 2 0 Utp14 protein FAM60A PF15396.6 CDJ61534.1 - 1.1 9.2 46.8 0.34 10.9 15.0 3.4 3 0 0 3 3 3 0 Protein Family FAM60A DUF913 PF06025.12 CDJ61534.1 - 1.4 7.8 39.1 0.81 8.6 11.4 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) eIF-3_zeta PF05091.12 CDJ61534.1 - 4 6.3 57.4 0.69 8.8 3.1 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PRCC PF10253.9 CDJ61534.1 - 4.2 8.1 66.5 0.1 13.4 16.2 3.7 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Neur_chan_memb PF02932.16 CDJ61534.1 - 4.8 7.2 47.3 1.6 8.7 0.9 3.2 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Cwf_Cwc_15 PF04889.12 CDJ61534.1 - 6.9 6.3 57.6 0.55 9.9 16.2 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein GAGA_bind PF06217.12 CDJ61534.1 - 9.5 6.4 46.2 3.4 7.9 15.5 3.2 3 0 0 3 3 3 0 GAGA binding protein-like family BUD22 PF09073.10 CDJ61535.1 - 4.1e-05 23.1 28.2 4.1e-05 23.1 28.2 5.8 4 1 1 5 5 5 3 BUD22 DUF966 PF06136.13 CDJ61535.1 - 0.00049 19.9 1.9 0.00049 19.9 1.9 6.0 4 1 2 6 6 6 1 Domain of unknown function (DUF966) TAXi_C PF14541.6 CDJ61535.1 - 0.012 15.5 0.0 0.8 9.5 0.1 2.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal RNA_pol_3_Rpc31 PF11705.8 CDJ61535.1 - 0.012 15.9 12.9 0.012 15.9 12.9 4.9 6 0 0 6 6 6 0 DNA-directed RNA polymerase III subunit Rpc31 RskA PF10099.9 CDJ61536.1 - 0.053 13.8 61.7 0.02 15.2 15.3 4.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA MACPF PF01823.19 CDJ61536.1 - 0.087 12.9 0.1 0.087 12.9 0.1 4.5 2 2 1 4 4 4 0 MAC/Perforin domain RskA PF10099.9 CDJ61537.1 - 0.00067 20.0 2.0 0.00067 20.0 2.0 7.4 1 1 5 7 7 7 2 Anti-sigma-K factor rskA RRM_1 PF00076.22 CDJ61538.1 - 7e-10 38.6 0.0 0.012 15.5 0.2 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RskA PF10099.9 CDJ61538.1 - 0.0068 16.7 17.0 0.0068 16.7 17.0 17.7 5 3 8 13 13 13 5 Anti-sigma-K factor rskA Peptidase_S9 PF00326.21 CDJ61539.1 - 1.3e-13 50.9 5.4 2.4e-06 27.2 1.2 3.8 2 1 1 3 3 3 3 Prolyl oligopeptidase family Nmad2 PF18753.1 CDJ61539.1 - 0.0083 15.6 0.2 0.0083 15.6 0.2 2.7 2 0 0 2 2 2 1 Nucleotide modification associated domain 2 LsmAD PF06741.13 CDJ61541.1 - 0.00037 21.0 4.1 0.00037 21.0 4.1 5.7 6 1 1 7 7 7 1 LsmAD domain SR-25 PF10500.9 CDJ61541.1 - 0.0021 17.7 1.6 0.0021 17.7 1.6 10.8 6 4 1 9 9 9 4 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 CDJ61541.1 - 0.016 15.8 3.3 0.016 15.8 3.3 12.8 3 1 4 7 7 7 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3381 PF11861.8 CDJ61542.1 - 5.5e-16 58.8 26.5 5.5e-16 58.8 26.5 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) SR-25 PF10500.9 CDJ61542.1 - 0.015 14.9 22.8 0.015 14.9 22.8 4.6 3 2 1 4 4 4 0 Nuclear RNA-splicing-associated protein Ctf8 PF09696.10 CDJ61542.1 - 0.037 14.4 0.4 0.037 14.4 0.4 4.2 4 1 0 4 4 4 0 Ctf8 DUF4386 PF14329.6 CDJ61542.1 - 0.35 10.7 7.2 0.58 10.0 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) RXT2_N PF08595.11 CDJ61542.1 - 9 6.3 31.4 0.096 12.7 5.1 3.8 4 0 0 4 4 4 0 RXT2-like, N-terminal N6_N4_Mtase PF01555.18 CDJ61543.1 - 0.00064 19.5 0.0 41 3.8 0.0 5.1 4 1 1 5 5 5 1 DNA methylase AAA_12 PF13087.6 CDJ61544.1 - 1.6e-34 119.2 0.0 2.9e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDJ61544.1 - 4.9e-15 56.0 6.1 6.7e-08 32.6 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 CDJ61544.1 - 4.9e-08 32.9 0.0 3.6e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDJ61544.1 - 1.3e-07 31.7 0.1 0.37 10.5 0.1 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDJ61544.1 - 1.8e-05 25.1 0.0 4.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDJ61544.1 - 0.01 16.2 0.4 0.053 13.9 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDJ61544.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 CDJ61544.1 - 0.65 9.9 3.1 15 5.5 0.4 2.9 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain PNK3P PF08645.11 CDJ61545.1 - 7.4e-38 129.8 0.0 2.3e-35 121.7 0.0 2.4 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDJ61545.1 - 4.2e-09 36.7 0.1 0.00013 22.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain tRNA_lig_kinase PF08303.11 CDJ61545.1 - 2.2e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_16 PF13191.6 CDJ61545.1 - 3.4e-05 24.3 0.1 9.5e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDJ61545.1 - 0.00021 20.9 0.0 0.0012 18.6 0.0 2.2 3 0 0 3 3 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDJ61545.1 - 0.00026 20.9 0.1 0.00087 19.2 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDJ61545.1 - 0.00039 20.7 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDJ61545.1 - 0.0028 17.6 0.1 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 CDJ61545.1 - 0.0032 18.0 0.1 0.016 15.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain MeaB PF03308.16 CDJ61545.1 - 0.0033 16.4 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 CDJ61545.1 - 0.0035 16.8 0.6 0.5 9.8 0.1 2.2 1 1 1 2 2 2 1 Chromatin associated protein KTI12 6PF2K PF01591.18 CDJ61545.1 - 0.0047 16.3 0.0 3.4 6.9 0.0 3.0 3 1 0 4 4 4 1 6-phosphofructo-2-kinase AAA_5 PF07728.14 CDJ61545.1 - 0.0049 16.9 0.1 0.07 13.1 0.0 2.8 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CDJ61545.1 - 0.014 14.7 0.1 0.047 13.0 0.1 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_28 PF13521.6 CDJ61545.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDJ61545.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CDJ61545.1 - 0.022 15.3 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 CDJ61545.1 - 0.032 14.6 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CDJ61545.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 CDJ61545.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 CDJ61545.1 - 0.064 13.7 0.0 1.2 9.6 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 CDJ61545.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 CDJ61545.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 CDJ61545.1 - 0.082 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain HAD PF12710.7 CDJ61545.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Spore_III_AB PF09548.10 CDJ61545.1 - 0.14 12.2 0.4 9 6.4 0.3 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AAA_17 PF13207.6 CDJ61545.1 - 0.55 10.7 2.6 2.8 8.4 0.0 3.0 3 1 1 4 4 3 0 AAA domain V-ATPase_G PF03179.15 CDJ61546.1 - 1.3e-09 38.5 11.1 2.5e-09 37.6 11.1 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Nmad5 PF18757.1 CDJ61546.1 - 0.013 15.7 1.0 0.025 14.8 1.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 V-ATPase_G_2 PF16999.5 CDJ61546.1 - 0.31 11.5 12.4 0.95 9.9 12.4 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit STAT_int PF02865.17 CDJ61546.1 - 0.44 11.0 3.7 0.99 9.9 1.0 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain DUF883 PF05957.13 CDJ61546.1 - 5.9 7.6 15.7 25 5.6 7.6 3.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) PRIMA1 PF16101.5 CDJ61547.1 - 0.13 12.3 0.6 0.21 11.7 0.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myco_arth_vir_N PF09610.10 CDJ61547.1 - 0.13 12.4 0.7 0.13 12.4 0.7 2.1 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) RRM_1 PF00076.22 CDJ61548.1 - 0.023 14.5 0.3 6 6.8 0.0 3.3 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DA1-like PF12315.8 CDJ61549.1 - 1.8e-08 34.0 0.0 0.00018 21.0 0.0 2.5 2 0 0 2 2 2 2 Protein DA1 ATF7IP_BD PF16788.5 CDJ61549.1 - 0.0053 16.9 1.4 0.0053 16.9 1.4 1.8 2 0 0 2 2 2 1 ATF-interacting protein binding domain UPF0561 PF10573.9 CDJ61549.1 - 2.1 8.5 6.0 5.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 Hamartin PF04388.12 CDJ61549.1 - 5.2 5.6 9.3 0.38 9.4 3.6 1.8 2 0 0 2 2 2 0 Hamartin protein Hydrolase_3 PF08282.12 CDJ61550.1 - 1e-42 146.7 0.0 4.2e-40 138.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CDJ61550.1 - 2.7e-12 46.8 0.0 5.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CDJ61550.1 - 2.8e-07 31.0 3.1 0.007 16.7 0.0 3.6 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDJ61550.1 - 0.00083 19.8 1.9 0.66 10.4 0.0 3.7 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 CDJ61550.1 - 0.095 11.8 0.0 0.75 8.9 0.0 2.1 1 1 0 1 1 1 0 Trehalose-phosphatase DHC_N1 PF08385.12 CDJ61551.1 - 1.4e-123 413.5 2.7 1.4e-123 413.5 2.7 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDJ61551.1 - 1.7e-72 244.7 8.6 1.7e-72 244.7 8.6 3.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DMA PF03474.14 CDJ61551.1 - 0.14 11.8 0.0 0.45 10.1 0.0 2.0 1 0 0 1 1 1 0 DMRTA motif Syntaxin_2 PF14523.6 CDJ61551.1 - 1.9 8.9 11.0 2.6 8.5 0.4 4.5 4 0 0 4 4 4 0 Syntaxin-like protein PI3K_P85_iSH2 PF16454.5 CDJ61551.1 - 4.1 7.0 11.9 5.6 6.5 2.3 3.7 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_TATA_bd PF12325.8 CDJ61551.1 - 6.1 7.1 10.2 58 4.0 0.1 5.6 5 0 0 5 5 5 0 TATA element modulatory factor 1 TATA binding SR-25 PF10500.9 CDJ61551.1 - 6.7 6.3 10.7 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_6 PF12774.7 CDJ61552.1 - 4e-82 275.8 0.7 5.6e-82 275.3 0.1 1.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ61552.1 - 3e-30 105.6 0.1 6.9e-30 104.4 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CDJ61552.1 - 7.2e-07 29.3 0.0 1.5e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ61552.1 - 0.005 17.4 0.0 0.031 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDJ61552.1 - 0.0079 16.6 0.1 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIN_4 PF13638.6 CDJ61552.1 - 0.025 14.9 0.2 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 PIN domain Cas_Csa4 PF09703.10 CDJ61552.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) YlbE PF14003.6 CDJ61552.1 - 0.13 12.7 1.0 0.55 10.7 0.1 2.3 2 0 0 2 2 2 0 YlbE-like protein AAR2 PF05282.11 CDJ61554.1 - 0.81 9.0 9.3 0.34 10.3 1.5 2.6 2 0 0 2 2 2 0 AAR2 protein SNARE_assoc PF09335.11 CDJ61555.1 - 1.1e-08 35.6 0.0 3.8e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Sporozoite_P67 PF05642.11 CDJ61555.1 - 7e-06 24.4 0.0 5.6e-05 21.4 0.0 1.9 1 1 1 2 2 2 1 Sporozoite P67 surface antigen BSP_II PF05432.11 CDJ61555.1 - 0.0039 16.9 3.0 0.0039 16.9 3.0 2.3 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.13 CDJ61555.1 - 0.0078 16.1 2.6 0.0078 16.1 2.6 2.8 3 0 0 3 3 3 1 Sigma-70, non-essential region SOBP PF15279.6 CDJ61555.1 - 0.29 11.7 37.2 1.7 9.2 19.0 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Utp14 PF04615.13 CDJ61555.1 - 1.1 7.7 32.7 0.52 8.8 16.3 2.0 2 0 0 2 2 2 0 Utp14 protein Med15 PF09606.10 CDJ61555.1 - 1.1 7.8 76.8 0.27 9.9 10.8 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM208_SND2 PF05620.11 CDJ61555.1 - 2.5 7.8 0.0 2.5 7.8 0.0 4.3 4 0 0 4 4 4 0 SRP-independent targeting protein 2/TMEM208 Apt1 PF10351.9 CDJ61555.1 - 4.1 6.1 26.6 0.16 10.8 4.7 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Zip PF02535.22 CDJ61555.1 - 8.6 5.5 25.8 8.2 5.5 10.3 2.5 2 1 0 2 2 2 0 ZIP Zinc transporter ACDC PF14733.6 CDJ61557.1 - 7.6e-17 61.4 0.1 7.6e-17 61.4 0.1 2.1 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.20 CDJ61557.1 - 1.6e-13 50.6 1.5 1.7e-07 31.3 0.6 2.6 2 0 0 2 2 2 2 AP2 domain Gti1_Pac2 PF09729.9 CDJ61557.1 - 1.9 8.6 17.0 3 7.9 0.4 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family PI3K_1B_p101 PF10486.9 CDJ61557.1 - 6.9 4.3 11.5 14 3.3 11.5 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Herpes_capsid PF06112.11 CDJ61558.1 - 0.1 12.6 20.4 0.028 14.5 11.4 2.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Macoilin PF09726.9 CDJ61559.1 - 2.1 6.8 10.5 2.3 6.7 10.5 1.1 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 CDJ61559.1 - 2.8 7.6 13.4 21 4.8 12.0 1.9 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CDJ61559.1 - 4.3 5.3 9.7 5.4 5.0 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 CDJ61560.1 - 1.9e-09 37.2 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2722 PF10846.8 CDJ61560.1 - 2.6e-05 23.4 10.8 2.6e-05 23.4 10.8 4.6 4 1 0 4 4 4 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ61560.1 - 0.00017 21.3 12.9 0.00017 21.3 12.9 4.4 4 0 0 4 4 4 3 Spt20 family DUF3306 PF11748.8 CDJ61560.1 - 0.018 15.9 1.3 0.018 15.9 1.3 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3306) TFIIA PF03153.13 CDJ61560.1 - 0.43 10.5 123.4 0.014 15.5 12.7 4.3 4 1 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CDJ61560.1 - 0.62 9.5 40.1 0.84 9.0 1.9 4.2 4 0 0 4 4 4 0 Stage II sporulation protein P (SpoIIP) Gti1_Pac2 PF09729.9 CDJ61560.1 - 0.66 10.0 31.7 0.35 10.9 0.8 4.3 4 0 0 4 4 4 0 Gti1/Pac2 family UQ_con PF00179.26 CDJ61561.1 - 8.2e-47 158.4 0.0 9e-47 158.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDJ61561.1 - 0.00054 19.7 0.0 0.00059 19.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDJ61561.1 - 0.0072 16.6 0.1 0.0078 16.5 0.1 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CDJ61561.1 - 0.056 13.3 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RCC1_2 PF13540.6 CDJ61562.1 - 4e-05 23.3 11.2 0.061 13.1 0.1 6.0 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat TSP_1 PF00090.19 CDJ61562.1 - 0.0061 16.8 1.1 0.015 15.5 1.1 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain RCC1 PF00415.18 CDJ61562.1 - 8.8 7.0 6.3 41 4.9 0.5 3.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat ANAPC4_WD40 PF12894.7 CDJ61563.1 - 0.0011 19.2 0.2 0.49 10.7 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CDJ61563.1 - 0.0022 17.3 1.3 0.0022 17.3 1.3 2.4 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 CDJ61563.1 - 0.0076 17.1 3.5 24 6.0 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.8 CDJ61563.1 - 0.031 12.9 0.4 0.057 12.1 0.3 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 EPL1 PF10513.9 CDJ61564.1 - 0.00027 21.4 11.1 0.01 16.2 4.2 3.2 3 0 0 3 3 3 2 Enhancer of polycomb-like DUF2828 PF11443.8 CDJ61564.1 - 0.089 10.9 8.0 0.085 10.9 3.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CDJ61564.1 - 0.22 10.5 17.9 0.14 11.1 2.7 2.8 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) O-antigen_lig PF13425.6 CDJ61564.1 - 0.27 10.0 0.5 0.41 9.4 0.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ctr PF04145.15 CDJ61564.1 - 0.29 11.8 8.8 7.6 7.1 2.8 3.3 3 0 0 3 3 3 0 Ctr copper transporter family Activator_LAG-3 PF11498.8 CDJ61564.1 - 0.43 9.5 49.8 0.31 10.0 37.9 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 MAJIN PF15077.6 CDJ61564.1 - 1.9 8.2 11.7 0.057 13.2 1.9 2.4 2 0 0 2 2 2 0 Membrane-anchored junction protein Suf PF05843.14 CDJ61564.1 - 2.1 8.3 23.0 0.021 14.8 4.3 3.5 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) Hid1 PF12722.7 CDJ61564.1 - 3.5 5.6 18.1 0.66 8.0 1.6 2.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 CDJ61564.1 - 4.7 6.2 7.2 0.97 8.4 1.7 2.2 2 0 0 2 2 2 0 Tumour-associated protein CLN3 PF02487.17 CDJ61564.1 - 6.3 5.7 12.9 0.49 9.4 4.3 2.5 3 0 0 3 3 3 0 CLN3 protein Mem_trans PF03547.18 CDJ61564.1 - 6.3 5.1 9.6 1.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Membrane transport protein VIT1 PF01988.19 CDJ61564.1 - 9.2 6.1 12.2 1.2 8.9 3.6 2.9 2 1 0 2 2 2 0 VIT family Connexin PF00029.19 CDJ61564.1 - 9.7 5.9 9.9 7.4 6.3 4.8 2.8 3 0 0 3 3 3 0 Connexin Transketolase_C PF02780.20 CDJ61565.1 - 4.8e-34 116.9 0.1 8e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CDJ61565.1 - 1.9e-25 89.6 0.0 3.2e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 CDJ61565.1 - 0.013 15.8 0.3 0.037 14.3 0.1 1.7 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II MIF4G PF02854.19 CDJ61566.1 - 3.6e-25 88.9 0.3 4.5e-25 88.5 0.3 1.1 1 0 0 1 1 1 1 MIF4G domain SR-25 PF10500.9 CDJ61567.1 - 4.4e-07 29.7 99.8 4.3e-05 23.2 12.2 6.7 6 0 0 6 6 6 5 Nuclear RNA-splicing-associated protein AAA_11 PF13086.6 CDJ61567.1 - 9.5 5.9 34.7 1.3 8.7 3.6 3.4 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 CDJ61569.1 - 9.1e-28 97.2 0.0 4e-27 95.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ61569.1 - 1.2e-25 90.0 0.0 2.7e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ61569.1 - 0.75 10.1 2.8 3.9 7.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain Cluap1 PF10234.9 CDJ61570.1 - 7.4e-11 41.9 19.4 7.4e-11 41.9 19.4 2.3 1 1 1 2 2 2 1 Clusterin-associated protein-1 COQ9 PF08511.11 CDJ61570.1 - 0.028 14.2 0.9 2.5 7.9 0.0 3.2 3 0 0 3 3 3 0 COQ9 TMCO5 PF14992.6 CDJ61570.1 - 0.41 10.2 14.9 0.13 11.8 10.2 2.1 1 1 1 2 2 2 0 TMCO5 family Peptidase_C15 PF01470.17 CDJ61571.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyroglutamyl peptidase ATG_C PF09333.11 CDJ61574.1 - 0.04 14.3 1.0 0.65 10.4 0.3 3.0 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain DUF4602 PF15375.6 CDJ61575.1 - 7.4e-05 23.1 4.3 7.4e-05 23.1 4.3 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4602) DUF444 PF04285.12 CDJ61575.1 - 0.016 14.3 3.9 0.037 13.1 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DYW_deaminase PF14432.6 CDJ61576.1 - 0.025 14.4 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Rbx_binding PF18113.1 CDJ61576.1 - 0.12 12.1 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain GCD14 PF08704.10 CDJ61576.1 - 0.13 11.9 0.6 0.17 11.5 0.4 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SNF2_N PF00176.23 CDJ61577.1 - 9.1e-54 182.5 0.0 9.1e-54 182.5 0.0 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ61577.1 - 6.4e-18 65.1 0.0 3e-17 63.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CDJ61577.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 CDJ61577.1 - 1e-08 35.3 0.3 2.1e-07 31.1 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDJ61577.1 - 3.2e-07 29.8 1.1 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 RskA PF10099.9 CDJ61578.1 - 0.0039 17.5 66.5 0.011 16.1 3.3 3.8 1 1 2 3 3 3 3 Anti-sigma-K factor rskA Monooxygenase_B PF04744.12 CDJ61578.1 - 0.089 11.6 1.8 0.15 10.9 1.8 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Vps39_2 PF10367.9 CDJ61579.1 - 0.0074 16.7 0.3 0.024 15.1 0.3 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Init_tRNA_PT PF04179.12 CDJ61579.1 - 0.043 14.1 2.0 0.1 12.9 0.7 2.4 2 0 0 2 2 2 0 Rit1 DUSP-like domain KxDL PF10241.9 CDJ61579.1 - 0.17 12.2 4.9 1 9.7 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF3450 PF11932.8 CDJ61579.1 - 0.22 10.8 8.8 1.7 7.9 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4636 PF15468.6 CDJ61579.1 - 1 9.0 4.9 2.1 8.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) HisKA_3 PF07730.13 CDJ61579.1 - 1.1 9.8 10.2 0.99 10.0 2.7 3.2 2 0 0 2 2 2 0 Histidine kinase CCDC85 PF10226.9 CDJ61579.1 - 4.4 6.9 6.5 5.4 6.7 0.0 3.3 3 0 0 3 3 3 0 CCDC85 family L27_2 PF09045.10 CDJ61580.1 - 0.11 12.5 0.2 20 5.2 0.0 2.3 2 0 0 2 2 2 0 L27_2 Prot_ATP_OB_N PF17758.1 CDJ61580.1 - 0.52 10.0 2.0 10 5.8 0.1 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DnaJ PF00226.31 CDJ61581.1 - 3e-20 72.1 1.9 3.8e-20 71.8 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 CDJ61581.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Transket_pyr PF02779.24 CDJ61582.1 - 1.6e-43 148.4 0.0 2.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDJ61582.1 - 3.2e-35 120.7 0.0 1.1e-34 118.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF4131 PF13567.6 CDJ61583.1 - 0.00056 19.6 0.4 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) RskA PF10099.9 CDJ61583.1 - 0.0057 17.0 5.6 0.0057 17.0 5.6 2.6 1 1 0 2 2 2 1 Anti-sigma-K factor rskA V_ATPase_I PF01496.19 CDJ61583.1 - 0.016 13.1 16.8 0.13 10.2 9.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SART-1 PF03343.13 CDJ61583.1 - 0.017 13.7 21.4 0.025 13.1 21.4 1.1 1 0 0 1 1 1 0 SART-1 family Phage_holin_3_3 PF16083.5 CDJ61583.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III DUF2052 PF09747.9 CDJ61583.1 - 0.17 12.0 22.0 0.4 10.8 13.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FHIPEP PF00771.20 CDJ61583.1 - 0.2 10.1 10.7 0.04 12.4 6.9 1.6 2 0 0 2 2 2 0 FHIPEP family O-antigen_lig PF13425.6 CDJ61583.1 - 0.3 9.8 1.3 0.48 9.1 1.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LRR19-TM PF15176.6 CDJ61583.1 - 0.59 10.1 6.9 6.1 6.9 3.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain CCSAP PF15748.5 CDJ61583.1 - 1.3 9.1 42.6 3.8 7.6 12.2 2.2 1 1 1 2 2 2 0 Centriole, cilia and spindle-associated DcuA_DcuB PF03605.14 CDJ61583.1 - 4 6.2 4.3 1.3 7.9 1.7 1.6 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter FAM176 PF14851.6 CDJ61583.1 - 5.1 6.8 26.7 0.063 12.9 10.3 3.1 2 1 1 3 3 3 0 FAM176 family FYDLN_acid PF09538.10 CDJ61583.1 - 5.4 7.7 14.9 0.19 12.5 6.8 2.6 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 CDJ61583.1 - 6.7 4.9 25.6 4.3 5.5 6.6 2.2 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.16 CDJ61583.1 - 9.8 5.3 13.0 1.1 8.4 7.8 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SfLAP PF11139.8 CDJ61584.1 - 0.75 9.2 6.3 1.9 7.9 0.5 3.4 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Presenilin PF01080.17 CDJ61585.1 - 0.0079 15.0 3.9 0.014 14.1 3.9 1.6 1 0 0 1 1 1 1 Presenilin DUF913 PF06025.12 CDJ61585.1 - 0.013 14.5 0.4 0.023 13.7 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CDJ61585.1 - 0.076 12.8 1.3 0.21 11.3 1.3 1.7 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CDJ61585.1 - 0.17 10.9 3.0 0.37 9.8 3.0 1.5 1 0 0 1 1 1 0 CLN3 protein SpoVR PF04293.13 CDJ61585.1 - 0.21 10.2 7.6 0.36 9.5 7.6 1.2 1 0 0 1 1 1 0 SpoVR like protein Pet20 PF08692.10 CDJ61585.1 - 0.21 12.3 4.3 0.12 13.1 1.3 2.0 2 0 0 2 2 2 0 Mitochondrial protein Pet20 FAM176 PF14851.6 CDJ61585.1 - 0.56 9.9 6.5 1.7 8.3 6.5 1.8 1 0 0 1 1 1 0 FAM176 family Folate_carrier PF01770.18 CDJ61585.1 - 1.7 7.3 4.6 2.9 6.5 1.6 2.4 3 0 0 3 3 3 0 Reduced folate carrier Sec62 PF03839.16 CDJ61585.1 - 8 5.9 8.0 17 4.8 8.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 SMC_N PF02463.19 CDJ61589.1 - 3e-28 98.8 1.0 4.2e-28 98.3 1.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDJ61589.1 - 7.2e-05 22.7 1.0 0.00012 22.0 1.0 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CDJ61589.1 - 0.00045 20.7 2.0 0.00052 20.5 0.6 1.9 2 1 0 2 2 2 1 ABC transporter AAA_15 PF13175.6 CDJ61589.1 - 0.0065 16.2 2.1 0.0093 15.7 2.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain FapA PF03961.13 CDJ61589.1 - 0.035 12.7 3.3 0.049 12.2 3.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nas2_N PF18265.1 CDJ61589.1 - 0.39 10.7 6.8 1.7 8.6 0.1 3.2 3 0 0 3 3 3 0 Nas2 N_terminal domain FlaC_arch PF05377.11 CDJ61589.1 - 3.6 8.0 5.3 4.4 7.8 0.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) NYD-SP28 PF14772.6 CDJ61590.1 - 0.0075 16.3 8.7 0.0075 16.3 8.7 2.3 1 1 1 2 2 2 1 Sperm tail 5_nucleotid PF05761.14 CDJ61590.1 - 0.066 12.1 5.1 0.08 11.8 5.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family FH2 PF02181.23 CDJ61590.1 - 0.15 11.2 8.9 0.28 10.2 1.1 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain bZIP_2 PF07716.15 CDJ61590.1 - 0.87 9.7 8.9 9.7 6.4 8.8 2.7 1 1 0 1 1 1 0 Basic region leucine zipper TMPIT PF07851.13 CDJ61590.1 - 1.3 8.2 6.9 3.6 6.8 6.9 1.7 1 1 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.17 CDJ61590.1 - 1.7 8.6 11.7 0.5 10.3 4.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 CDJ61590.1 - 2 8.7 14.5 0.77 10.1 2.0 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain OmpH PF03938.14 CDJ61590.1 - 2.7 8.3 20.6 0.5 10.7 11.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Muted PF14942.6 CDJ61590.1 - 5.5 7.3 9.8 6.8 7.0 4.5 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DivIC PF04977.15 CDJ61590.1 - 6.5 6.6 15.6 3.7 7.4 8.3 2.9 2 1 0 2 2 2 0 Septum formation initiator tRNA-synt_1 PF00133.22 CDJ61591.1 - 0.093 11.0 0.3 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Glyco_trans_1_3 PF13528.6 CDJ61591.1 - 0.18 11.0 0.0 1.2 8.3 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 1 DUF2722 PF10846.8 CDJ61592.1 - 3e-05 23.2 10.5 3e-05 23.2 10.5 3.1 2 1 1 3 3 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CDJ61592.1 - 0.00013 22.1 15.4 0.00013 22.1 15.4 2.8 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CDJ61592.1 - 0.00084 19.4 3.7 0.00084 19.4 3.7 2.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) ANAPC_CDC26 PF10471.9 CDJ61592.1 - 0.0032 18.3 14.3 0.0032 18.3 14.3 4.3 4 0 0 4 4 3 1 Anaphase-promoting complex APC subunit CDC26 Isy1 PF06246.12 CDJ61592.1 - 0.05 13.2 8.6 0.091 12.3 1.4 2.2 2 0 0 2 2 2 0 Isy1-like splicing family SMYLE_N PF18615.1 CDJ61592.1 - 0.2 11.2 8.5 0.26 10.8 1.8 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PA26 PF04636.13 CDJ61592.1 - 0.37 9.7 10.5 0.11 11.4 3.8 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Gti1_Pac2 PF09729.9 CDJ61592.1 - 0.37 10.9 3.4 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4569 PF15133.6 CDJ61592.1 - 0.47 10.1 21.1 2.1 8.0 9.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Neur_chan_memb PF02932.16 CDJ61592.1 - 0.5 10.4 7.5 0.7 9.9 0.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CDJ61592.1 - 1.3 8.7 10.8 0.34 10.7 1.1 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain TUSC2 PF15000.6 CDJ61592.1 - 1.6 9.0 9.7 0.033 14.5 2.1 2.1 2 1 0 2 2 2 0 Tumour suppressor candidate 2 MecA PF05389.12 CDJ61592.1 - 2.3 7.8 9.0 0.4 10.3 2.4 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Hid1 PF12722.7 CDJ61592.1 - 2.5 6.1 9.4 0.32 9.1 0.4 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PRCC PF10253.9 CDJ61592.1 - 3 8.6 29.5 0.045 14.6 6.3 3.3 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Med15 PF09606.10 CDJ61592.1 - 3.1 6.4 49.5 0.53 8.9 21.9 2.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.20 CDJ61592.1 - 3.2 6.1 8.3 0.42 9.0 1.9 2.1 2 0 0 2 2 2 0 FHIPEP family Sec62 PF03839.16 CDJ61592.1 - 3.5 7.1 11.4 0.44 10.0 0.9 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 Rxt3 PF08642.10 CDJ61592.1 - 4.5 8.0 5.3 2.5 8.9 0.4 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Exonuc_VII_L PF02601.15 CDJ61592.1 - 6.8 6.2 19.1 1.5 8.3 5.3 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Folliculin PF11704.8 CDJ61592.1 - 7.1 6.5 8.2 0.46 10.4 0.8 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MMR1 PF08505.10 CDJ61592.1 - 9.9 6.4 18.6 0.14 12.5 3.7 2.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Allexi_40kDa PF05549.11 CDJ61593.1 - 0.0052 16.3 8.3 0.0052 16.3 8.3 4.8 3 1 2 5 5 5 1 Allexivirus 40kDa protein BCNT PF07572.12 CDJ61594.1 - 1.2e-07 31.7 0.2 1.2e-07 31.7 0.2 2.4 2 0 0 2 2 2 1 Bucentaur or craniofacial development GP44 PF17510.2 CDJ61594.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Gene product 44 LAP1C PF05609.12 CDJ61594.1 - 0.14 11.2 16.1 0.17 10.9 16.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SR-25 PF10500.9 CDJ61594.1 - 0.42 10.2 31.2 2.3 7.8 31.2 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 CDJ61594.1 - 2.7 5.6 15.5 3.5 5.3 15.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ndc1_Nup PF09531.10 CDJ61594.1 - 6.2 5.4 9.0 6.9 5.2 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FSA_C PF10479.9 CDJ61595.1 - 3 5.9 13.3 3.7 5.6 13.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2722 PF10846.8 CDJ61596.1 - 0.0019 17.2 3.3 0.0019 17.2 3.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) CCSAP PF15748.5 CDJ61596.1 - 0.0091 16.2 6.1 0.012 15.8 6.1 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated TFIIA PF03153.13 CDJ61596.1 - 0.02 14.9 11.9 0.026 14.6 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ61596.1 - 0.022 15.1 7.2 0.051 13.9 7.2 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain LCIB_C_CA PF18599.1 CDJ61596.1 - 0.058 12.7 0.7 0.085 12.1 0.7 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Suf PF05843.14 CDJ61596.1 - 0.17 11.9 7.6 0.22 11.5 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 CDJ61596.1 - 0.24 10.1 5.0 0.33 9.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin CDK2AP PF09806.9 CDJ61596.1 - 0.88 9.6 8.1 3.2 7.7 0.6 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TraG-D_C PF12696.7 CDJ61596.1 - 0.9 9.5 12.7 1.1 9.2 2.2 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF2967 PF11179.8 CDJ61596.1 - 1.8 6.5 12.9 2.7 6.0 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) SR-25 PF10500.9 CDJ61597.1 - 1.9e-06 27.7 10.1 3.7e-06 26.7 10.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2722 PF10846.8 CDJ61597.1 - 1.3e-05 24.4 4.3 1.3e-05 24.4 4.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) MID_MedPIWI PF18296.1 CDJ61597.1 - 0.0019 18.0 3.5 0.0019 18.0 3.5 1.7 2 0 0 2 2 2 1 MID domain of medPIWI DUF4355 PF14265.6 CDJ61597.1 - 0.0024 18.1 9.0 0.0024 18.1 9.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4355) SICA_C PF12879.7 CDJ61597.1 - 0.0025 17.8 7.9 0.22 11.5 0.0 4.2 2 2 2 4 4 4 2 SICA C-terminal inner membrane domain Velvet PF11754.8 CDJ61597.1 - 0.0027 17.7 4.1 0.0027 17.7 4.1 1.6 2 0 0 2 2 2 1 Velvet factor CCSAP PF15748.5 CDJ61597.1 - 0.006 16.8 13.4 0.006 16.8 13.4 1.9 2 0 0 2 2 2 1 Centriole, cilia and spindle-associated FAM199X PF15814.5 CDJ61597.1 - 0.043 12.9 8.5 0.082 11.9 8.5 1.4 1 0 0 1 1 1 0 Protein family FAM199X TFIIA PF03153.13 CDJ61597.1 - 0.092 12.7 25.6 0.15 12.0 20.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.8 CDJ61597.1 - 0.14 12.4 11.7 0.37 11.1 11.7 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain SprA-related PF12118.8 CDJ61597.1 - 0.26 10.4 22.3 0.42 9.7 22.3 1.2 1 0 0 1 1 1 0 SprA-related family CLN3 PF02487.17 CDJ61597.1 - 0.35 9.9 2.0 0.61 9.1 2.0 1.4 1 0 0 1 1 1 0 CLN3 protein TCP PF03634.13 CDJ61597.1 - 0.7 10.4 13.9 0.22 12.1 10.7 1.7 2 0 0 2 2 1 0 TCP family transcription factor SIR4_SID PF16991.5 CDJ61597.1 - 1.2 9.1 13.3 0.12 12.4 8.3 1.8 2 0 0 2 2 2 0 Sir4 SID domain Thioredoxin_15 PF18403.1 CDJ61597.1 - 1.5 8.7 7.7 3.9 7.3 7.7 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Corona_nucleoca PF00937.18 CDJ61597.1 - 1.7 7.6 10.2 2.7 7.0 10.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Presenilin PF01080.17 CDJ61597.1 - 1.7 7.3 12.5 2.9 6.6 12.5 1.3 1 0 0 1 1 1 0 Presenilin DUF4240 PF14024.6 CDJ61597.1 - 1.8 8.8 7.2 10 6.3 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4240) Folliculin PF11704.8 CDJ61597.1 - 2.7 7.8 11.3 40 4.0 11.3 2.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Methyltransf_14 PF08484.11 CDJ61597.1 - 3 7.6 5.6 3.2 7.5 1.9 2.2 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain DUF4207 PF13904.6 CDJ61597.1 - 3.4 7.3 22.6 0.22 11.2 17.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF4446 PF14584.6 CDJ61597.1 - 3.6 7.5 5.4 2.4 8.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HbrB PF08539.11 CDJ61597.1 - 3.8 7.5 15.0 0.14 12.1 5.9 2.3 1 1 1 2 2 2 0 HbrB-like DUF702 PF05142.12 CDJ61597.1 - 6.4 7.3 10.8 2.5 8.6 7.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF702) Neur_chan_memb PF02932.16 CDJ61597.1 - 6.4 6.8 6.7 13 5.8 6.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tyrosinase PF00264.20 CDJ61597.1 - 6.8 6.9 8.0 1 9.6 3.3 1.8 2 0 0 2 2 2 0 Common central domain of tyrosinase DRY_EERY PF09750.9 CDJ61597.1 - 8.2 6.7 13.2 4.9 7.4 8.5 2.2 2 0 0 2 2 2 0 Alternative splicing regulator DUF5466 PF17554.2 CDJ61599.1 - 0.082 13.1 0.2 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5466) PROCN PF08083.11 CDJ61600.1 - 4.7e-230 763.3 6.2 8.2e-230 762.5 6.2 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain U6-snRNA_bdg PF10596.9 CDJ61600.1 - 1.2e-86 288.6 1.8 2.8e-86 287.3 1.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDJ61600.1 - 1.1e-82 275.4 0.9 2.7e-82 274.2 0.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDJ61600.1 - 3.4e-71 237.5 0.0 6.5e-71 236.7 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CDJ61600.1 - 2.2e-46 156.1 0.2 4.8e-46 155.0 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 SRP-alpha_N PF04086.13 CDJ61600.1 - 4 7.3 14.6 7 6.5 14.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 CDJ61600.1 - 5.6 5.6 12.2 9.3 4.9 12.2 1.3 1 0 0 1 1 1 0 Presenilin LRR_6 PF13516.6 CDJ61602.1 - 1.4e-07 31.0 5.2 0.34 11.1 0.1 4.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 CDJ61602.1 - 0.0017 18.7 0.1 1.2 9.7 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDJ61602.1 - 0.011 15.5 4.4 8 6.3 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CDJ61602.1 - 0.012 16.0 2.4 13 6.8 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat FumaraseC_C PF10415.9 CDJ61602.1 - 0.93 10.0 0.0 0.93 10.0 0.0 3.0 2 0 0 2 2 2 0 Fumarase C C-terminus Tir_receptor_N PF07490.11 CDJ61602.1 - 1 9.1 3.8 2.1 8.1 3.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus RskA PF10099.9 CDJ61603.1 - 0.0019 18.5 9.7 0.0019 18.5 9.7 19.4 6 6 9 17 17 17 4 Anti-sigma-K factor rskA MOZ_SAS PF01853.18 CDJ61605.1 - 5.5e-62 208.6 0.0 9.9e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDJ61605.1 - 3.5e-17 61.8 0.1 6.5e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDJ61605.1 - 2.5e-10 40.1 0.0 1.2e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CDJ61605.1 - 0.0066 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec1 PF00995.23 CDJ61607.1 - 4.2e-66 224.4 0.0 3.1e-65 221.5 0.0 1.9 1 1 0 1 1 1 1 Sec1 family TFIIA PF03153.13 CDJ61609.1 - 0.085 12.8 11.1 0.1 12.5 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TniQ PF06527.11 CDJ61609.1 - 0.099 13.4 3.4 3.6 8.3 3.4 2.4 1 1 0 1 1 1 0 TniQ MctB PF11382.8 CDJ61610.1 - 0.036 13.8 0.2 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF4834 PF16118.5 CDJ61610.1 - 0.11 13.4 0.0 0.32 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Leo1 PF04004.13 CDJ61611.1 - 0.0037 17.1 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 Leo1-like protein ThiF PF00899.21 CDJ61612.1 - 7.7e-50 169.5 0.0 7.5e-49 166.3 0.0 1.9 2 0 0 2 2 2 1 ThiF family Tr-sialidase_C PF11052.8 CDJ61612.1 - 0.04 14.0 4.8 0.04 14.0 4.8 2.4 3 0 0 3 3 3 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal IMUP PF15761.5 CDJ61612.1 - 0.044 14.5 2.7 0.12 13.1 2.7 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Mso1_Sec1_bdg PF14475.6 CDJ61612.1 - 0.2 11.3 0.4 0.47 10.1 0.4 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 DUF755 PF05501.11 CDJ61612.1 - 2.3 8.5 8.8 4 7.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.9 CDJ61612.1 - 3.9 7.0 7.7 6 6.4 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cupin_8 PF13621.6 CDJ61613.1 - 0.025 14.3 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Cupin-like domain Fe_bilin_red PF05996.12 CDJ61613.1 - 0.051 13.3 1.1 0.087 12.5 1.1 1.4 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase FHIPEP PF00771.20 CDJ61613.1 - 0.053 12.0 0.3 0.071 11.6 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family FAM176 PF14851.6 CDJ61613.1 - 0.06 13.0 2.7 0.1 12.2 2.7 1.4 1 0 0 1 1 1 0 FAM176 family Herpes_DNAp_acc PF04929.12 CDJ61613.1 - 0.11 11.5 1.4 0.16 10.9 1.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4637 PF15470.6 CDJ61613.1 - 0.12 12.1 6.0 0.3 10.8 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.13 CDJ61613.1 - 0.13 11.2 10.0 0.19 10.7 10.0 1.2 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CDJ61613.1 - 0.15 10.8 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CDJ61613.1 - 0.16 11.4 6.1 0.26 10.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RskA PF10099.9 CDJ61613.1 - 0.17 12.1 10.4 0.34 11.2 10.4 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA GOLD_2 PF13897.6 CDJ61613.1 - 0.25 11.8 4.8 1.1 9.7 4.9 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Saw1 PF11561.8 CDJ61613.1 - 0.6 9.6 4.9 0.98 8.9 4.9 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CPSF100_C PF13299.6 CDJ61613.1 - 0.77 9.9 5.2 0.17 12.1 1.6 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 CDJ61613.1 - 1.5 7.0 6.6 0.25 9.6 3.3 1.3 2 0 0 2 2 2 0 CDC45-like protein Roughex PF06020.11 CDJ61613.1 - 4.6 6.2 10.3 7.1 5.6 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1840 PF08895.11 CDJ61613.1 - 7.9 6.9 9.5 8 6.8 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF2722 PF10846.8 CDJ61614.1 - 0.00022 20.3 2.0 0.00022 20.3 2.0 6.8 3 2 3 6 6 6 1 Protein of unknown function (DUF2722) RskA PF10099.9 CDJ61614.1 - 0.0014 19.0 11.0 0.0014 19.0 11.0 8.8 3 2 2 5 5 5 1 Anti-sigma-K factor rskA Acetyltransf_1 PF00583.25 CDJ61615.1 - 7.9e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ61615.1 - 2e-06 28.1 0.0 4.5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDJ61615.1 - 0.00041 20.3 0.1 0.0009 19.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 7tm_6 PF02949.20 CDJ61615.1 - 0.044 12.9 0.2 0.059 12.5 0.2 1.2 1 0 0 1 1 1 0 7tm Odorant receptor Glyoxalase PF00903.25 CDJ61616.1 - 5.8e-12 45.9 0.0 6.7e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CDJ61616.1 - 0.054 13.8 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Melibiase_2 PF16499.5 CDJ61617.1 - 2.7e-07 30.0 0.0 4.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CDJ61617.1 - 0.0038 17.3 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DCR PF14047.6 CDJ61617.1 - 0.061 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region UBA2_C PF16195.5 CDJ61617.1 - 0.16 12.7 0.1 0.16 12.7 0.1 1.7 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus TerC PF03741.16 CDJ61617.1 - 0.23 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein TerC family SNF2_N PF00176.23 CDJ61618.1 - 2.8e-36 125.0 0.0 7.1e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ61618.1 - 3.5e-18 66.0 0.0 8.5e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ61618.1 - 7.7e-07 29.3 0.0 2.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDJ61618.1 - 0.00037 19.8 0.0 0.00085 18.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SLC12 PF03522.15 CDJ61618.1 - 2 7.3 6.9 5.3 5.9 6.9 1.6 1 0 0 1 1 1 0 Solute carrier family 12 DUF4618 PF15397.6 CDJ61619.1 - 0.015 14.8 7.1 1.6 8.1 3.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PNTB PF02233.16 CDJ61620.1 - 4e-178 593.1 20.5 4e-178 593.1 20.5 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDJ61620.1 - 1e-65 221.1 0.5 1.9e-65 220.1 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 CDJ61620.1 - 8.7e-30 103.0 8.0 8.7e-30 103.0 8.0 4.5 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_N PF05222.15 CDJ61620.1 - 3.9e-28 98.4 0.0 7.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 CDJ61620.1 - 9e-06 25.2 0.3 0.13 11.7 0.2 2.3 1 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 CDJ61620.1 - 0.013 15.2 0.4 0.22 11.2 0.2 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AAA_11 PF13086.6 CDJ61622.1 - 1.1e-56 192.5 0.0 2.8e-29 102.7 0.7 2.7 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 CDJ61622.1 - 2.3e-56 190.6 0.0 4e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDJ61622.1 - 5e-11 43.1 1.0 0.00024 21.4 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CDJ61622.1 - 1.1e-10 41.6 0.1 0.00012 21.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CDJ61622.1 - 0.00088 19.1 0.0 0.049 13.4 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDJ61622.1 - 0.036 13.6 0.0 2.9 7.3 0.1 2.8 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 CDJ61622.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 CDJ61622.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain RRM_1 PF00076.22 CDJ61624.1 - 1.7e-36 123.8 0.1 1.8e-13 50.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDJ61624.1 - 8.9e-06 26.7 0.2 8.9e-06 26.7 0.2 2.9 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CDJ61624.1 - 7.5e-05 22.5 0.0 0.13 12.1 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 CDJ61624.1 - 0.037 13.9 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_3 PF08777.11 CDJ61624.1 - 0.055 13.5 0.3 5.6 7.1 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif EF-hand_1 PF00036.32 CDJ61625.1 - 9e-05 21.8 0.2 0.00035 19.9 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CDJ61625.1 - 0.0011 19.4 0.1 0.0054 17.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDJ61625.1 - 0.0064 16.3 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CDJ61625.1 - 0.2 11.6 0.4 0.64 9.9 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair Uso1_p115_C PF04871.13 CDJ61625.1 - 8.7 6.7 10.8 1.7 9.0 4.5 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Amidase PF01425.21 CDJ61626.1 - 1.9e-06 27.1 5.2 0.014 14.4 0.4 2.4 2 0 0 2 2 2 2 Amidase FHIPEP PF00771.20 CDJ61626.1 - 0.31 9.5 5.2 0.86 8.0 5.2 1.7 1 0 0 1 1 1 0 FHIPEP family DUF719 PF05334.13 CDJ61626.1 - 0.83 9.8 9.0 0.62 10.2 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF719) SpoIIP PF07454.11 CDJ61626.1 - 3.9 6.8 9.1 0.5 9.8 2.4 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 CDJ61626.1 - 5 6.0 11.9 1.7 7.5 4.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAM33 PF02330.16 CDJ61626.1 - 5.9 6.8 12.8 0.12 12.3 4.2 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein SAC3_GANP PF03399.16 CDJ61627.1 - 1.6e-25 90.1 0.1 2.2e-14 53.6 0.0 4.4 4 1 0 4 4 4 2 SAC3/GANP family DXP_synthase_N PF13292.6 CDJ61628.1 - 2.9e-54 184.1 0.1 4.9e-54 183.4 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 CDJ61628.1 - 3e-12 46.6 1.0 1.5e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDJ61628.1 - 0.00025 20.1 0.0 0.00059 18.9 0.0 1.6 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 CDJ61628.1 - 0.00035 19.6 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain THEG4 PF15834.5 CDJ61628.1 - 0.067 13.2 1.5 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Testis highly expressed protein 4 TFIIA PF03153.13 CDJ61628.1 - 0.7 9.8 12.3 0.98 9.3 2.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CDJ61628.1 - 0.9 9.8 25.9 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SUIM_assoc PF16619.5 CDJ61628.1 - 3.9 7.6 12.2 3.8 7.6 4.8 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 CDJ61629.1 - 1.6e-07 31.8 2.7 1.6e-07 31.8 2.7 2.8 3 1 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 CDJ61629.1 - 3.7e-05 23.8 0.0 0.0071 16.3 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_35 PF14516.6 CDJ61629.1 - 0.0017 17.2 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain DUF815 PF05673.13 CDJ61629.1 - 0.0022 17.2 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CDJ61629.1 - 0.0077 16.5 0.6 0.026 14.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain CLP1_P PF16575.5 CDJ61629.1 - 0.016 15.1 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 CDJ61629.1 - 0.024 14.6 0.0 0.09 12.7 0.0 2.1 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CDJ61629.1 - 0.026 14.5 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 CDJ61629.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 CDJ61629.1 - 0.82 9.2 5.0 1.4 8.5 5.0 1.3 1 0 0 1 1 1 0 Spt20 family Metallophos PF00149.28 CDJ61630.1 - 5.6e-23 82.5 0.0 7.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDJ61630.1 - 0.014 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF2813 PF11398.8 CDJ61630.1 - 0.051 12.8 0.5 0.071 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) RskA PF10099.9 CDJ61630.1 - 0.1 12.8 14.0 0.23 11.7 14.0 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF507 PF04368.13 CDJ61630.1 - 0.16 11.9 0.3 0.22 11.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF507) PAT1 PF09770.9 CDJ61631.1 - 0.82 7.9 31.9 1.4 7.1 31.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TctA PF01970.16 CDJ61631.1 - 1.5 7.5 6.1 2.1 7.0 6.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Tubulin PF00091.25 CDJ61632.1 - 3.2e-68 229.8 0.0 6.1e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDJ61632.1 - 3e-42 143.8 0.0 4.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDJ61632.1 - 0.00028 21.2 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDJ61632.1 - 0.0053 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CDJ61632.1 - 0.0066 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF202 PF02656.15 CDJ61633.1 - 0.79 10.2 7.8 0.81 10.2 4.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Hydrolase PF00702.26 CDJ61635.1 - 0.023 15.0 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEC-1_N PF04625.13 CDJ61636.1 - 7.6 5.4 12.4 10 5.0 12.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SURF6 PF04935.12 CDJ61637.1 - 3.6 7.3 121.9 1.8e+04 -5.4 25.3 4.5 1 1 0 2 2 2 0 Surfeit locus protein 6 RIO1 PF01163.22 CDJ61638.1 - 9.3e-35 119.9 0.6 3e-25 88.9 0.1 2.7 2 0 0 2 2 2 2 RIO1 family PcfJ PF14284.6 CDJ61638.1 - 0.012 15.5 0.8 0.012 15.5 0.8 2.7 3 0 0 3 3 3 0 PcfJ-like protein PilM PF07419.12 CDJ61638.1 - 7.1 6.8 5.6 6.3 7.0 0.1 2.3 2 0 0 2 2 2 0 PilM Qn_am_d_aII PF14930.6 CDJ61639.1 - 0.12 12.7 0.0 8.4 6.8 0.0 3.1 2 1 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II SoxG PF04268.12 CDJ61639.1 - 0.38 10.9 8.1 24 5.1 0.1 4.9 2 1 3 5 5 5 0 Sarcosine oxidase, gamma subunit family Oxysterol_BP PF01237.18 CDJ61640.1 - 1.2e-100 336.9 0.0 4.9e-59 200.1 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein VasL PF12486.8 CDJ61640.1 - 0.0065 16.3 3.3 0.017 15.0 3.3 1.7 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL CENP-Q PF13094.6 CDJ61640.1 - 0.011 16.0 5.0 0.025 14.8 5.0 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CREPT PF16566.5 CDJ61640.1 - 0.013 15.7 3.5 0.024 14.8 3.5 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3467 PF11950.8 CDJ61640.1 - 0.077 13.2 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) betaPIX_CC PF16523.5 CDJ61640.1 - 0.094 12.6 3.9 0.19 11.6 3.9 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Prp19 PF08606.11 CDJ61640.1 - 0.14 12.2 7.8 0.24 11.4 6.7 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like HAUS-augmin3 PF14932.6 CDJ61640.1 - 0.18 11.4 6.3 0.35 10.4 6.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CRR7 PF12095.8 CDJ61640.1 - 0.81 10.2 5.0 1.8 9.1 5.0 1.5 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 PH PF00169.29 CDJ61641.1 - 5e-12 46.3 0.2 9.1e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 PH domain Surface_antigen PF11054.8 CDJ61644.1 - 3.8e-12 46.4 6.7 2.2e-08 34.1 3.7 3.1 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen DUF5364 PF17322.2 CDJ61644.1 - 0.14 12.5 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5364) Surface_antigen PF11054.8 CDJ61645.1 - 8.5e-15 55.1 13.4 3.8e-09 36.6 7.6 5.0 2 2 0 2 2 2 2 Sporozoite TA4 surface antigen CoatB PF10389.9 CDJ61645.1 - 0.12 12.3 1.8 0.29 11.0 1.8 1.6 1 0 0 1 1 1 0 Bacteriophage coat protein B Spt20 PF12090.8 CDJ61646.1 - 0.018 14.7 4.6 0.023 14.3 4.6 1.2 1 0 0 1 1 1 0 Spt20 family Cys_Met_Meta_PP PF01053.20 CDJ61646.1 - 0.3 9.6 1.3 0.51 8.8 0.4 1.7 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF2722 PF10846.8 CDJ61646.1 - 0.38 9.6 6.1 0.51 9.2 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 CDJ61646.1 - 0.81 8.7 5.1 1.2 8.2 5.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein FAD_oxidored PF12831.7 CDJ61646.1 - 6.2 6.1 8.7 0.47 9.7 3.3 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase DUF2722 PF10846.8 CDJ61647.1 - 0.00011 21.3 9.1 0.00011 21.3 9.1 5.5 4 1 1 5 5 5 3 Protein of unknown function (DUF2722) IMUP PF15761.5 CDJ61647.1 - 0.0086 16.8 8.7 0.0086 16.8 8.7 3.5 2 1 0 2 2 2 1 Immortalisation up-regulated protein RskA PF10099.9 CDJ61647.1 - 0.011 16.0 14.7 0.011 16.0 14.7 6.5 2 2 2 4 4 4 0 Anti-sigma-K factor rskA DUF3371 PF11851.8 CDJ61647.1 - 0.038 15.1 6.1 0.038 15.1 6.1 6.5 5 1 0 5 5 5 0 Domain of unknown function (DUF3371) ANAPC_CDC26 PF10471.9 CDJ61648.1 - 0.0039 18.0 15.8 0.0039 18.0 15.8 10.3 4 3 2 6 6 6 1 Anaphase-promoting complex APC subunit CDC26 Fasciclin PF02469.22 CDJ61648.1 - 0.013 15.7 0.2 0.039 14.2 0.2 1.8 1 0 0 1 1 1 0 Fasciclin domain DEAD PF00270.29 CDJ61649.1 - 6.1e-10 39.1 0.1 4.9e-07 29.7 0.5 2.7 1 1 1 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CDJ61649.1 - 2e-09 38.0 3.6 2e-09 38.0 3.6 2.8 3 1 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 CDJ61649.1 - 0.00053 20.0 2.7 0.038 14.0 0.0 2.6 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit Spore_III_AF PF09581.10 CDJ61649.1 - 0.28 11.2 0.1 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Retinal PF15449.6 CDJ61650.1 - 3.9 5.1 9.6 4.6 4.9 9.6 1.1 1 0 0 1 1 1 0 Retinal protein 2-oxoacid_dh PF00198.23 CDJ61651.1 - 1.9e-66 223.8 0.0 2.6e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDJ61651.1 - 1.4e-16 60.0 1.2 2.9e-16 59.1 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDJ61651.1 - 1.2e-15 57.5 3.3 2.2e-15 56.7 1.7 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDJ61651.1 - 4.7e-07 29.5 0.6 3.9e-06 26.6 0.4 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 CDJ61651.1 - 3.3e-06 26.5 3.1 2.5e-05 23.6 3.1 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 CDJ61651.1 - 0.04 13.8 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CDJ61651.1 - 0.081 12.7 0.1 0.59 9.9 0.0 2.2 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 His_Phos_1 PF00300.22 CDJ61653.1 - 0.00057 19.6 0.1 0.12 12.1 0.0 3.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Serglycin PF04360.12 CDJ61653.1 - 0.0067 16.4 2.3 0.013 15.4 2.3 1.4 1 0 0 1 1 1 1 Serglycin DUF4746 PF15928.5 CDJ61653.1 - 0.061 12.7 3.0 0.091 12.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) dsDNA_bind PF01984.20 CDJ61653.1 - 0.34 11.2 1.9 7.3 6.9 0.1 3.0 3 0 0 3 3 3 0 Double-stranded DNA-binding domain SPC22 PF04573.12 CDJ61654.1 - 6.4e-45 152.7 0.0 8e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit LSM PF01423.22 CDJ61655.1 - 6e-16 57.9 0.2 8.9e-16 57.3 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDJ61655.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Hfq protein KI67R PF08065.12 CDJ61656.1 - 0.044 14.3 4.8 5.7 7.5 0.6 2.9 2 1 0 2 2 2 0 KI67R (NUC007) repeat zf-C3HC4 PF00097.25 CDJ61656.1 - 0.094 12.6 0.5 0.19 11.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 CDJ61657.1 - 0.0017 18.4 2.5 0.0017 18.4 2.5 5.3 5 1 0 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATPase-cat_bd PF12156.8 CDJ61657.1 - 0.034 14.9 2.6 0.22 12.3 2.6 2.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase SKA2 PF16740.5 CDJ61657.1 - 0.042 13.6 6.5 0.21 11.4 0.1 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2730 PF10805.8 CDJ61657.1 - 0.6 10.2 4.3 0.9 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Occludin_ELL PF07303.13 CDJ61657.1 - 0.63 10.8 5.8 2.8 8.7 0.9 3.2 2 0 0 2 2 2 0 Occludin homology domain DUF5320 PF17253.2 CDJ61657.1 - 1.1 10.4 4.5 37 5.5 0.9 3.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF5082 PF16888.5 CDJ61657.1 - 1.9 8.8 8.8 0.34 11.2 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 CDJ61657.1 - 3 8.0 11.1 1.3 9.2 4.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Cnn_1N PF07989.11 CDJ61657.1 - 4.2 7.6 13.5 1.5 9.1 2.1 3.8 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 CDJ61657.1 - 8.5 6.9 6.1 15 6.1 0.4 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CDJ61657.1 - 8.7 6.2 22.9 0.052 13.3 5.0 3.8 4 0 0 4 4 4 0 Septum formation initiator XPG_N PF00752.17 CDJ61658.1 - 0.028 14.9 0.6 37 4.9 0.0 3.7 1 1 3 4 4 4 0 XPG N-terminal domain PIN_4 PF13638.6 CDJ61658.1 - 0.046 14.0 1.2 1.6 9.1 1.2 2.6 1 1 0 1 1 1 0 PIN domain Not3 PF04065.15 CDJ61659.1 - 1.9e-22 79.8 21.8 1.9e-22 79.8 21.8 3.4 2 2 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component RskA PF10099.9 CDJ61659.1 - 6.3 7.0 0.0 6.3 7.0 0.0 6.6 3 2 1 5 5 5 0 Anti-sigma-K factor rskA Pkinase PF00069.25 CDJ61660.1 - 0.024 14.0 0.2 0.024 14.0 0.2 2.2 2 0 0 2 2 2 0 Protein kinase domain Ribosomal_L36e PF01158.18 CDJ61660.1 - 0.064 13.5 0.9 0.35 11.1 0.9 2.3 1 0 0 1 1 1 0 Ribosomal protein L36e Pkinase_Tyr PF07714.17 CDJ61660.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase ISP3_C PF18045.1 CDJ61661.1 - 0.16 11.8 0.2 15 5.5 0.0 2.8 2 1 0 2 2 2 0 ISP3 C-terminal PNISR PF15996.5 CDJ61662.1 - 0.084 13.1 14.1 0.23 11.7 14.1 1.7 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR V_ATPase_I PF01496.19 CDJ61662.1 - 0.14 10.1 3.0 0.2 9.5 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 CDJ61662.1 - 0.16 11.1 0.3 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFB6 PF17110.5 CDJ61662.1 - 0.3 10.8 3.6 0.69 9.6 3.6 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 CDJ61662.1 - 0.75 8.5 10.4 1.3 7.7 10.4 1.4 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CDJ61662.1 - 0.81 9.7 14.3 1.2 9.2 10.9 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFIIA PF03153.13 CDJ61662.1 - 0.98 9.3 26.6 2.9 7.8 26.6 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 CDJ61662.1 - 1.3 8.8 4.4 2.8 7.7 4.4 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AXIN1_TNKS_BD PF16646.5 CDJ61662.1 - 3.1 8.8 7.7 5 8.1 3.6 3.1 1 1 1 2 2 2 0 Axin-1 tankyrase binding domain RRM_1 PF00076.22 CDJ61663.1 - 1.6e-07 31.1 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2339 PF10101.9 CDJ61663.1 - 0.0019 16.9 0.1 0.0021 16.7 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) RRM_occluded PF16842.5 CDJ61663.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif PepSY_TM PF03929.16 CDJ61663.1 - 0.068 12.8 1.3 0.22 11.1 0.5 2.2 2 0 0 2 2 2 0 PepSY-associated TM region DUF1211 PF06736.11 CDJ61663.1 - 6.4 7.3 6.6 12 6.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Lactamase_B_2 PF12706.7 CDJ61664.1 - 1.4e-07 31.2 1.7 3.4e-06 26.7 0.6 3.3 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDJ61664.1 - 0.00037 20.6 0.1 0.0037 17.3 0.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily AHSA1 PF08327.11 CDJ61664.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein RNA_pol_Rpb2_6 PF00562.28 CDJ61667.1 - 2.2e-73 247.6 0.0 9.1e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDJ61667.1 - 7.9e-27 94.1 0.0 1.3e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CDJ61667.1 - 7.2e-15 54.9 0.0 2e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CDJ61667.1 - 0.0042 17.1 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CDJ61667.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CDJ61667.1 - 0.21 11.2 0.0 0.46 10.1 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Avl9 PF09794.9 CDJ61668.1 - 0.25 10.0 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Hep_59 PF07052.11 CDJ61670.1 - 9e-12 45.7 1.1 9e-12 45.7 1.1 2.0 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF1269 PF06897.12 CDJ61671.1 - 0.78 10.1 7.7 2.7 8.3 7.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 CDJ61671.1 - 2.2 8.4 27.1 8.8 6.4 27.1 2.1 1 0 0 1 1 1 0 Glycine zipper RVT_1 PF00078.27 CDJ61674.1 - 3.5e-21 75.7 0.0 4.2e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-B_box PF00643.24 CDJ61675.1 - 3.5e-07 30.3 3.1 6.6e-07 29.4 3.1 1.4 1 0 0 1 1 1 1 B-box zinc finger PH PF00169.29 CDJ61675.1 - 0.0021 18.5 0.0 0.0057 17.1 0.0 1.7 1 0 0 1 1 1 1 PH domain ZZ PF00569.17 CDJ61675.1 - 0.0027 17.5 2.2 0.0057 16.4 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 CDJ61675.1 - 0.0035 17.5 1.0 0.0081 16.3 1.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Peptidase_M14 PF00246.24 CDJ61676.1 - 4.4e-24 85.8 4.1 4.4e-24 85.8 4.1 4.1 3 2 1 4 4 4 1 Zinc carboxypeptidase DUF2722 PF10846.8 CDJ61676.1 - 1.4e-06 27.6 14.5 5.9e-05 22.2 5.7 8.2 6 2 1 7 7 7 4 Protein of unknown function (DUF2722) Gti1_Pac2 PF09729.9 CDJ61676.1 - 0.53 10.3 54.0 0.78 9.8 1.5 5.4 5 0 0 5 5 5 0 Gti1/Pac2 family RskA PF10099.9 CDJ61676.1 - 1.8 8.8 86.2 0.28 11.5 2.5 8.3 2 1 3 6 6 6 0 Anti-sigma-K factor rskA RskA PF10099.9 CDJ61678.1 - 0.003 17.9 8.5 0.003 17.9 8.5 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Adeno_PIX PF03955.14 CDJ61678.1 - 0.019 15.1 10.0 0.11 12.7 0.2 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Exonuc_VII_L PF02601.15 CDJ61678.1 - 0.023 14.3 6.9 0.029 14.0 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit P53_C PF11619.8 CDJ61678.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.8 1 1 2 3 3 3 0 Transcription factor P53 - C terminal domain DUF4347 PF14252.6 CDJ61678.1 - 0.17 11.8 6.1 0.031 14.1 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Robl_LC7 PF03259.17 CDJ61678.1 - 0.18 11.6 3.3 1.5 8.7 0.6 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain CSG2 PF16965.5 CDJ61678.1 - 0.23 10.4 0.6 0.3 10.0 0.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator PAT1 PF09770.9 CDJ61678.1 - 0.55 8.4 14.1 0.63 8.3 14.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 CDJ61678.1 - 2 8.4 6.1 2.6 8.1 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 CDJ61678.1 - 3.5 6.5 12.4 3.9 6.3 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4175 PF13779.6 CDJ61678.1 - 4.2 5.1 26.0 5.6 4.8 26.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CDJ61680.1 - 0.073 13.1 25.6 0.1 12.6 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CDJ61681.1 - 0.00064 19.4 21.5 0.00064 19.4 21.5 2.3 2 1 0 2 2 2 1 Spt20 family TFIIA PF03153.13 CDJ61681.1 - 0.015 15.4 34.3 0.27 11.2 1.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MDM31_MDM32 PF08118.11 CDJ61681.1 - 0.016 13.9 1.7 0.046 12.4 0.0 2.0 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins RNase_H2_suC PF08615.11 CDJ61681.1 - 0.031 14.4 3.5 1.1 9.4 0.5 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NAM-associated PF14303.6 CDJ61681.1 - 0.17 12.6 20.2 0.2 12.3 4.2 2.6 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 CDJ61681.1 - 0.7 9.5 42.1 1.5 8.4 6.0 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 CDJ61681.1 - 2.1 7.3 12.6 8.4 5.3 7.8 2.2 2 0 0 2 2 2 0 Solute carrier family 12 TCP PF03634.13 CDJ61681.1 - 5.5 7.5 22.1 13 6.3 1.0 3.1 3 0 0 3 3 3 0 TCP family transcription factor Pinin_SDK_memA PF04696.13 CDJ61681.1 - 5.8 7.0 30.5 0.51 10.4 13.9 2.7 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region AFT PF08731.11 CDJ61681.1 - 6.3 7.2 12.4 10 6.6 1.6 2.6 2 1 0 2 2 2 0 Transcription factor AFT eIF-3_zeta PF05091.12 CDJ61681.1 - 7.4 5.4 13.9 1.3 8.0 8.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2052 PF09747.9 CDJ61681.1 - 7.7 6.6 26.0 3.7 7.6 9.8 2.4 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CotH PF08757.11 CDJ61681.1 - 8.1 5.9 10.1 2.3 7.6 0.5 2.2 2 0 0 2 2 2 0 CotH kinase protein RskA PF10099.9 CDJ61682.1 - 0.00018 21.8 12.6 0.00018 21.8 12.6 6.3 1 1 3 4 4 4 1 Anti-sigma-K factor rskA Nucleoside_tran PF01733.18 CDJ61682.1 - 0.44 9.9 0.0 0.44 9.9 0.0 3.1 4 0 0 4 4 4 0 Nucleoside transporter CDC45 PF02724.14 CDJ61682.1 - 0.57 8.4 27.7 0.018 13.4 4.0 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA PF00004.29 CDJ61684.1 - 2.8e-10 40.7 0.0 4.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CLP1_N PF16573.5 CDJ61685.1 - 3.5e-14 52.8 0.0 3.5e-14 52.8 0.0 2.6 3 0 0 3 3 2 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 CDJ61685.1 - 4.6e-13 49.4 5.5 2e-10 40.8 0.0 2.9 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2368 PF10166.9 CDJ61685.1 - 0.017 14.7 9.9 0.04 13.5 9.9 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Phage_G PF02306.15 CDJ61685.1 - 0.03 14.1 0.2 0.06 13.1 0.2 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) FliG_N PF14842.6 CDJ61685.1 - 0.044 14.3 6.3 0.093 13.3 6.3 1.5 1 0 0 1 1 1 0 FliG N-terminal domain OKR_DC_1_C PF03711.15 CDJ61685.1 - 0.11 12.8 5.3 0.28 11.5 4.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain AAA PF00004.29 CDJ61685.1 - 0.14 12.5 0.5 6 7.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) EIF4E-T PF10477.9 CDJ61685.1 - 0.15 10.9 10.0 0.2 10.4 10.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E ABC_tran PF00005.27 CDJ61685.1 - 0.2 12.2 2.3 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter POX PF07526.11 CDJ61685.1 - 0.4 11.3 12.2 1.2 9.7 12.2 1.8 1 0 0 1 1 1 0 Associated with HOX AAA_23 PF13476.6 CDJ61685.1 - 1.1 9.8 5.9 5 7.6 4.6 2.1 2 0 0 2 2 2 0 AAA domain FliP PF00813.20 CDJ61685.1 - 1.5 8.7 5.6 2.8 7.8 5.6 1.4 1 0 0 1 1 1 0 FliP family DUF3533 PF12051.8 CDJ61685.1 - 3 6.7 6.6 5.6 5.8 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF2722 PF10846.8 CDJ61687.1 - 0.0012 17.9 10.7 0.0016 17.5 10.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF3464 PF11947.8 CDJ61687.1 - 0.0039 17.0 2.9 0.0059 16.4 2.9 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 SpoIIP PF07454.11 CDJ61687.1 - 0.007 15.9 5.4 0.0083 15.6 5.4 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CDJ61687.1 - 0.01 16.0 7.2 0.02 15.1 7.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RP-C_C PF11800.8 CDJ61687.1 - 0.028 14.5 7.8 0.039 14.0 7.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 CDJ61687.1 - 0.028 13.2 8.7 0.032 13.0 8.7 1.2 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 CDJ61687.1 - 0.052 12.2 15.4 0.061 12.0 15.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.13 CDJ61687.1 - 0.052 14.2 13.6 0.062 14.0 13.0 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tau95_N PF17682.1 CDJ61687.1 - 0.077 13.2 2.8 0.36 11.0 2.1 2.2 2 0 0 2 2 2 0 Tau95 Triple barrel domain TERB2 PF15101.6 CDJ61687.1 - 0.085 12.9 13.9 0.11 12.5 12.9 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CSG2 PF16965.5 CDJ61687.1 - 0.088 11.7 1.4 0.11 11.4 1.4 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator YceD PF02620.17 CDJ61687.1 - 0.099 12.8 8.6 0.21 11.7 8.6 1.5 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD OATP PF03137.20 CDJ61687.1 - 0.14 10.4 1.2 0.19 10.0 1.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MscS_TM PF12794.7 CDJ61687.1 - 0.14 11.0 6.6 0.2 10.5 6.6 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RR_TM4-6 PF06459.12 CDJ61687.1 - 0.16 11.8 9.9 0.24 11.2 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 CDJ61687.1 - 0.16 11.7 4.2 0.22 11.3 4.2 1.2 1 0 0 1 1 1 0 Connexin Ureide_permease PF07168.11 CDJ61687.1 - 0.17 10.6 2.5 0.25 10.0 2.5 1.2 1 0 0 1 1 1 0 Ureide permease Ctr PF04145.15 CDJ61687.1 - 0.19 12.3 1.2 0.29 11.8 1.2 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF4746 PF15928.5 CDJ61687.1 - 0.19 11.1 8.8 0.28 10.6 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RskA PF10099.9 CDJ61687.1 - 0.2 11.9 15.9 0.062 13.6 2.0 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 CDJ61687.1 - 0.25 10.9 26.5 0.43 10.2 26.5 1.4 1 0 0 1 1 1 0 Spt20 family XRN_N PF03159.18 CDJ61687.1 - 0.25 10.7 5.9 0.38 10.1 5.9 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus RXT2_N PF08595.11 CDJ61687.1 - 0.26 11.3 11.0 0.49 10.4 11.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal eIF-3_zeta PF05091.12 CDJ61687.1 - 0.48 9.3 11.3 0.63 9.0 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 CDJ61687.1 - 0.49 10.4 6.9 0.87 9.6 6.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Cellulose_synt PF03552.14 CDJ61687.1 - 0.52 8.7 1.9 0.62 8.5 1.9 1.1 1 0 0 1 1 1 0 Cellulose synthase PIP5K PF01504.18 CDJ61687.1 - 0.69 9.1 8.5 1 8.5 8.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 CDJ61687.1 - 0.73 8.8 4.3 1 8.3 4.3 1.2 1 0 0 1 1 1 0 CLN3 protein Spore_coat_CotO PF14153.6 CDJ61687.1 - 0.99 9.3 18.0 1.5 8.7 18.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.16 CDJ61687.1 - 1.1 9.3 6.4 1.6 8.7 6.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 CDJ61687.1 - 1.1 9.0 8.5 1.7 8.3 8.5 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.15 CDJ61687.1 - 1.1 8.0 4.0 1.4 7.8 4.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDJ61687.1 - 1.2 6.9 10.2 1.5 6.6 10.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family D123 PF07065.14 CDJ61687.1 - 1.5 7.9 11.7 2.3 7.3 11.7 1.2 1 0 0 1 1 1 0 D123 YABBY PF04690.13 CDJ61687.1 - 1.6 9.3 4.9 2.7 8.5 4.9 1.4 1 0 0 1 1 1 0 YABBY protein MMR1 PF08505.10 CDJ61687.1 - 1.9 8.7 15.9 0.79 10.0 13.7 1.4 2 0 0 2 2 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CDJ61687.1 - 2.9 6.6 7.9 3.8 6.2 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1980 PF09323.10 CDJ61687.1 - 3 7.7 11.8 2.9 7.8 9.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SET PF00856.28 CDJ61687.1 - 3.2 8.1 5.1 8.8 6.7 5.2 1.7 1 1 0 1 1 1 0 SET domain TFB6 PF17110.5 CDJ61687.1 - 4 7.2 9.4 6.6 6.4 9.4 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH F-protein PF00469.20 CDJ61687.1 - 5.2 6.6 13.9 7.4 6.1 13.0 1.7 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef DDHD PF02862.17 CDJ61687.1 - 5.7 7.0 14.4 6.9 6.8 14.4 1.3 1 1 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 CDJ61687.1 - 7 4.9 4.9 8.8 4.6 4.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_hydro_63 PF03200.16 CDJ61688.1 - 9.7 4.8 10.9 22 3.7 10.9 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Secretin_N_2 PF07655.13 CDJ61689.1 - 8.4 7.0 13.5 21 5.7 13.5 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain STIMATE PF12400.8 CDJ61690.1 - 5.2e-32 111.0 2.0 6.4e-32 110.7 2.0 1.1 1 0 0 1 1 1 1 STIMATE family PAT1 PF09770.9 CDJ61691.1 - 0.32 9.2 35.4 0.39 8.9 35.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 CDJ61691.1 - 0.46 8.7 23.0 0.62 8.3 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HEV_ORF1 PF02444.16 CDJ61691.1 - 2.1 9.0 13.6 0.16 12.6 3.4 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) GREB1 PF15782.5 CDJ61691.1 - 6.1 3.8 24.3 8 3.4 24.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YL1 PF05764.13 CDJ61691.1 - 7 6.7 34.3 1.8 8.6 31.1 1.6 2 0 0 2 2 2 0 YL1 nuclear protein IPP-2 PF04979.14 CDJ61692.1 - 8.9e-16 58.8 12.5 8.9e-16 58.8 12.5 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) HAUS2 PF15003.6 CDJ61692.1 - 0.006 16.3 0.4 0.0085 15.8 0.4 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF4574 PF15141.6 CDJ61692.1 - 0.54 10.2 4.0 1.3 9.0 4.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SR-25 PF10500.9 CDJ61692.1 - 9.1 5.8 17.2 1.2 8.7 9.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TMEM215 PF15746.5 CDJ61693.1 - 0.25 10.8 6.1 0.29 10.6 6.1 1.1 1 0 0 1 1 1 0 TMEM215 family PAT1 PF09770.9 CDJ61693.1 - 0.76 8.0 42.5 0.79 7.9 42.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.15 CDJ61693.1 - 2.2 7.0 31.4 2.7 6.7 31.4 1.1 1 0 0 1 1 1 0 Caldesmon SRP-alpha_N PF04086.13 CDJ61693.1 - 3.3 7.6 25.1 3.6 7.4 25.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2828 PF11443.8 CDJ61693.1 - 6.1 4.8 18.7 8.6 4.3 18.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1387 PF07139.11 CDJ61693.1 - 7.5 6.2 25.6 9.8 5.8 25.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 CDJ61693.1 - 9.6 4.9 32.3 13 4.4 32.3 1.2 1 0 0 1 1 1 0 Presenilin Golgin_A5 PF09787.9 CDJ61693.1 - 9.8 5.5 39.0 11 5.3 39.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5308 PF17233.2 CDJ61694.1 - 0.15 12.3 1.4 0.16 12.2 1.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) NOA36 PF06524.12 CDJ61694.1 - 0.33 10.2 19.3 0.37 10.1 19.3 1.1 1 0 0 1 1 1 0 NOA36 protein MRNIP PF15749.5 CDJ61694.1 - 0.59 10.9 10.6 0.66 10.7 10.6 1.1 1 0 0 1 1 1 0 MRN-interacting protein CobT PF06213.12 CDJ61694.1 - 2.2 7.6 26.2 2.3 7.6 26.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 CDJ61694.1 - 2.5 6.3 21.3 2.6 6.2 21.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDJ61694.1 - 3.3 5.8 26.5 3.4 5.8 26.5 1.0 1 0 0 1 1 1 0 Nop14-like family Folate_carrier PF01770.18 CDJ61694.1 - 3.8 6.1 3.6 4.2 6.0 3.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_pol_Rpc4 PF05132.14 CDJ61694.1 - 4 7.8 9.6 4.6 7.7 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 CDJ61694.1 - 4.9 6.0 29.0 5.1 6.0 29.0 1.0 1 0 0 1 1 1 0 Paf1 Mpp10 PF04006.12 CDJ61694.1 - 5.7 5.3 26.7 6 5.2 26.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 CDJ61694.1 - 5.9 6.6 10.0 6.1 6.5 10.0 1.0 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 CDJ61694.1 - 6.4 4.7 32.0 6.8 4.7 32.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 CDJ61694.1 - 6.7 6.4 11.8 7.9 6.2 11.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3306 PF11748.8 CDJ61694.1 - 7.3 7.5 12.0 8.1 7.3 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) V_ATPase_I PF01496.19 CDJ61694.1 - 9 4.1 11.6 8.7 4.1 11.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3682 PF12446.8 CDJ61695.1 - 4.5e-05 23.9 4.7 6.8e-05 23.4 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) Tim54 PF11711.8 CDJ61695.1 - 0.032 13.0 0.3 0.045 12.6 0.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ACPS PF01648.20 CDJ61695.1 - 0.063 13.4 0.4 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily Ydc2-catalyt PF09159.10 CDJ61695.1 - 1.2 8.8 4.6 4.3 7.0 4.6 1.8 1 1 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Med21 PF11221.8 CDJ61697.1 - 1.7e-12 47.8 0.2 2.1e-12 47.5 0.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GCN5L1 PF06320.13 CDJ61697.1 - 0.014 15.6 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) APG6_N PF17675.1 CDJ61697.1 - 0.031 14.8 2.2 0.044 14.3 2.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 CDJ61697.1 - 3.8 7.7 7.1 1.1 9.4 3.1 2.0 1 1 1 2 2 2 0 Basic region leucine zipper SID-1_RNA_chan PF13965.6 CDJ61698.1 - 0.11 10.8 1.7 0.14 10.6 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Metaviral_G PF09595.10 CDJ61699.1 - 0.045 13.8 0.4 0.074 13.1 0.4 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein LCIB_C_CA PF18599.1 CDJ61700.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SARAF PF06682.12 CDJ61701.1 - 6.2e-05 22.8 19.2 8.7e-05 22.3 0.0 3.3 2 1 1 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Hydrolase PF00702.26 CDJ61701.1 - 0.0022 18.3 0.0 0.0022 18.3 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Utp14 PF04615.13 CDJ61701.1 - 0.0023 16.6 31.6 0.031 12.9 21.8 2.2 1 1 1 2 2 2 2 Utp14 protein AAA_6 PF12774.7 CDJ61705.1 - 2.2e-141 470.6 0.0 1e-140 468.4 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDJ61705.1 - 6e-82 275.9 18.6 6e-82 275.9 18.6 3.4 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 CDJ61705.1 - 7.4e-19 68.1 2.1 2.2e-18 66.6 0.3 3.0 3 1 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDJ61705.1 - 2.4e-17 63.2 0.0 6.3e-11 42.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDJ61705.1 - 1.7e-05 25.4 0.1 0.24 11.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CDJ61705.1 - 0.00011 22.6 0.1 0.1 13.0 0.0 3.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDJ61705.1 - 0.0018 18.6 0.2 4.9 7.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CDJ61705.1 - 0.0037 17.6 0.0 4.1 7.8 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CDJ61705.1 - 0.0086 15.6 0.1 0.6 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDJ61705.1 - 0.009 16.2 3.1 3.1 7.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CDJ61705.1 - 0.013 15.2 0.7 3.8 7.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CDJ61705.1 - 0.021 15.2 0.1 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.10 CDJ61705.1 - 0.037 13.5 0.2 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 CDJ61705.1 - 0.086 12.6 0.2 3.1 7.5 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 CDJ61705.1 - 0.1 12.3 5.6 11 5.6 0.0 4.2 3 1 1 4 4 4 0 Cytidylate kinase MeaB PF03308.16 CDJ61705.1 - 0.11 11.5 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4094 PF13334.6 CDJ61705.1 - 0.96 9.9 5.2 0.42 11.1 0.2 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) ABC_tran PF00005.27 CDJ61705.1 - 2.5 8.6 0.0 2.5 8.6 0.0 3.1 4 0 0 4 4 3 0 ABC transporter Kelch_3 PF13415.6 CDJ61706.1 - 3.3e-17 62.3 14.7 4.5e-07 30.0 0.4 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDJ61706.1 - 2.1e-16 59.5 1.8 3.6e-07 30.0 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDJ61706.1 - 1.1e-13 50.9 5.6 1.5e-07 31.3 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CDJ61706.1 - 4.1e-12 45.5 15.0 1e-07 31.4 0.2 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDJ61706.1 - 1.2e-11 44.5 4.3 0.00027 21.1 0.1 4.8 5 0 0 5 5 5 3 Kelch motif TIG PF01833.24 CDJ61706.1 - 8.8e-07 28.9 0.6 2e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 IPT/TIG domain Kelch_2 PF07646.15 CDJ61706.1 - 3.4e-06 26.8 10.3 0.018 15.0 0.1 5.2 4 1 0 4 4 4 1 Kelch motif Metallophos_2 PF12850.7 CDJ61707.1 - 1.5e-20 74.1 0.0 1.8e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDJ61707.1 - 0.00012 22.7 1.2 0.0074 16.8 0.3 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase CHCH PF06747.13 CDJ61708.1 - 2e-05 24.6 2.6 3.3e-05 23.9 2.6 1.4 1 0 0 1 1 1 1 CHCH domain M_domain PF12938.7 CDJ61708.1 - 0.0053 16.6 2.8 0.0062 16.4 2.8 1.2 1 0 0 1 1 1 1 M domain of GW182 Pet191_N PF10203.9 CDJ61708.1 - 0.2 12.0 3.6 0.28 11.5 3.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Ribosomal_L7Ae PF01248.26 CDJ61710.1 - 1e-22 79.6 1.5 1.9e-22 78.8 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDJ61710.1 - 0.041 13.9 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 RskA PF10099.9 CDJ61711.1 - 4.5e-05 23.8 10.7 4.5e-05 23.8 10.7 5.5 2 2 2 4 4 4 1 Anti-sigma-K factor rskA Macoilin PF09726.9 CDJ61711.1 - 0.12 11.0 44.1 0.21 10.1 44.1 1.4 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CDJ61712.1 - 0.0037 16.9 9.5 0.0037 16.9 9.5 7.3 4 3 3 7 7 7 1 Nuclear RNA-splicing-associated protein CitMHS_2 PF16980.5 CDJ61712.1 - 0.047 12.4 0.3 0.14 10.7 0.3 1.9 1 0 0 1 1 1 0 Putative citrate transport XPG_I PF00867.18 CDJ61713.1 - 2.3e-08 34.3 0.1 2.3e-08 34.3 0.1 2.9 3 0 0 3 3 3 1 XPG I-region HHH_2 PF12826.7 CDJ61713.1 - 0.00088 19.3 1.1 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CDJ61713.1 - 0.0056 17.3 0.0 0.035 14.7 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CDJ61713.1 - 0.033 14.8 0.0 0.033 14.8 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain CDK5_activator PF03261.15 CDJ61713.1 - 5.2 6.5 12.4 7.9 5.9 12.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.9 CDJ61713.1 - 6.4 4.9 36.2 8.6 4.5 36.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_9 PF14580.6 CDJ61714.1 - 5.1e-34 117.3 0.3 8.5e-30 103.5 0.2 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CDJ61714.1 - 9.8e-07 28.5 2.8 2.7e-06 27.1 1.0 2.4 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CDJ61714.1 - 6e-05 23.3 8.5 0.0034 17.8 2.2 3.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDJ61714.1 - 3.5 8.5 6.6 20 6.2 0.2 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat CAF1C_H4-bd PF12265.8 CDJ61720.1 - 2.2e-17 63.1 0.0 4.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CDJ61720.1 - 0.00037 20.7 0.0 6.9 7.1 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDJ61720.1 - 0.00066 20.4 7.6 0.37 11.8 0.0 5.4 6 1 0 6 6 6 2 WD domain, G-beta repeat RskA PF10099.9 CDJ61720.1 - 0.0064 16.8 26.2 0.025 14.9 6.3 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Secretin_N_2 PF07655.13 CDJ61720.1 - 1.5 9.4 8.9 2.4 8.8 1.7 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Symplekin_C PF12295.8 CDJ61721.1 - 2.3e-35 122.4 0.8 2.3e-35 122.4 0.8 2.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF908 PF06012.12 CDJ61722.1 - 0.11 11.9 13.8 0.015 14.8 5.9 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) MMU163 PF17119.5 CDJ61722.1 - 0.12 11.5 1.4 0.26 10.4 1.4 1.6 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SPX PF03105.19 CDJ61722.1 - 0.31 10.9 16.3 0.42 10.5 16.3 1.4 1 1 0 1 1 1 0 SPX domain Peroxin-3 PF04882.12 CDJ61722.1 - 0.47 9.4 7.9 1.2 8.1 7.9 1.6 1 1 0 1 1 1 0 Peroxin-3 PH_RBD PF12068.8 CDJ61722.1 - 1.1 8.7 7.3 0.14 11.6 2.3 1.9 1 1 1 2 2 2 0 Rab-binding domain (RBD) Apt1 PF10351.9 CDJ61722.1 - 6.5 5.5 17.2 9.2 5.0 17.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CDJ61723.1 - 0.0001 22.0 4.5 0.0001 22.0 4.5 3.8 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ61723.1 - 0.00095 19.3 25.3 0.00095 19.3 25.3 1.8 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 CDJ61723.1 - 3 8.0 25.9 0.61 10.2 3.0 3.8 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Pet20 PF08692.10 CDJ61723.1 - 3.9 8.2 10.6 1.2 9.9 0.4 3.6 4 0 0 4 4 4 0 Mitochondrial protein Pet20 TRAUB PF08164.12 CDJ61723.1 - 5 7.7 7.0 0.93 10.1 0.6 2.8 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Neur_chan_memb PF02932.16 CDJ61724.1 - 0.09 12.8 0.1 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EHD_N PF16880.5 CDJ61725.1 - 3.9e-14 52.2 0.9 6.6e-14 51.5 0.9 1.3 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 CDJ61725.1 - 6.1e-06 26.4 0.0 9.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CDJ61725.1 - 0.0064 16.7 0.0 0.009 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 CDJ61725.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CDJ61725.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 CDJ61725.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 CDJ61725.1 - 0.22 11.7 0.0 0.4 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 CDJ61728.1 - 0.0081 14.8 8.9 0.01 14.4 8.9 1.1 1 0 0 1 1 1 1 Macoilin family Utp14 PF04615.13 CDJ61728.1 - 0.068 11.7 10.1 0.084 11.4 10.1 1.1 1 0 0 1 1 1 0 Utp14 protein SPRY PF00622.28 CDJ61728.1 - 0.085 13.0 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 SPRY domain LisH PF08513.11 CDJ61728.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 LisH UPF0270 PF06794.12 CDJ61728.1 - 0.19 11.9 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) PPP4R2 PF09184.11 CDJ61728.1 - 0.79 9.3 14.2 1.1 8.8 14.2 1.2 1 0 0 1 1 1 0 PPP4R2 GEMIN8 PF15348.6 CDJ61728.1 - 3 8.1 6.7 4.8 7.4 6.7 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Menin PF05053.13 CDJ61728.1 - 3.9 5.7 12.1 6.1 5.1 12.1 1.4 1 0 0 1 1 1 0 Menin Hid1 PF12722.7 CDJ61728.1 - 4.4 5.3 9.4 5.4 5.0 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 CDJ61728.1 - 6.5 5.4 12.2 9.2 4.9 12.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3682 PF12446.8 CDJ61729.1 - 0.0063 17.0 9.6 0.0063 17.0 9.6 10.8 7 2 3 10 10 10 1 Protein of unknown function (DUF3682) DUF2722 PF10846.8 CDJ61730.1 - 0.001 18.2 2.9 0.0013 17.8 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) K_channel_TID PF07941.11 CDJ61730.1 - 0.01 16.3 13.2 0.01 16.3 13.2 5.5 3 2 2 5 5 4 0 Potassium channel Kv1.4 tandem inactivation domain DUF4667 PF15700.5 CDJ61730.1 - 0.02 15.0 4.4 0.029 14.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) FAM60A PF15396.6 CDJ61730.1 - 0.14 12.1 0.9 0.21 11.6 0.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF5521 PF17659.1 CDJ61730.1 - 0.2 9.4 3.7 0.26 9.1 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Med15 PF09606.10 CDJ61730.1 - 0.23 10.1 23.9 0.33 9.6 23.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5427 PF10310.9 CDJ61730.1 - 0.27 10.1 11.8 0.36 9.7 11.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 CDJ61730.1 - 0.38 9.5 4.0 0.46 9.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDJ61730.1 - 0.94 7.5 3.2 1.2 7.1 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SUIM_assoc PF16619.5 CDJ61730.1 - 6.1 7.0 19.4 0.41 10.8 11.6 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IATP PF04568.12 CDJ61730.1 - 7.7 7.0 22.5 7.6 7.0 6.8 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP SR-25 PF10500.9 CDJ61731.1 - 0.00015 21.5 4.3 0.00015 21.5 4.3 5.8 5 2 1 6 6 6 3 Nuclear RNA-splicing-associated protein DUF3299 PF11736.8 CDJ61731.1 - 0.032 14.2 0.5 0.032 14.2 0.5 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3299) DUF745 PF05335.13 CDJ61732.1 - 0.34 10.6 24.7 0.097 12.4 5.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF948 PF06103.11 CDJ61732.1 - 2.3 8.5 5.4 0.67 10.3 0.3 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 CDJ61732.1 - 3.9 6.7 17.6 4.8 6.4 2.1 2.2 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 CDJ61732.1 - 5.9 5.7 27.1 4.7 6.0 6.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDJ61732.1 - 6.4 6.0 17.5 5.4 6.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 CDJ61732.1 - 6.7 6.8 18.9 0.25 11.4 0.4 3.4 3 0 0 3 3 3 0 Short coiled-coil protein YabA PF06156.13 CDJ61732.1 - 9.1 7.0 20.2 5.6 7.7 1.7 3.2 2 1 1 3 3 3 0 Initiation control protein YabA OST3_OST6 PF04756.13 CDJ61733.1 - 2.8e-18 66.3 0.0 6.9e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Vps54_N PF10475.9 CDJ61735.1 - 0.55 9.5 4.2 1.8 7.8 4.2 1.8 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Ribosomal_L15e PF00827.17 CDJ61736.1 - 2.2e-88 295.0 9.5 2.5e-88 294.8 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 BCIP PF13862.6 CDJ61737.1 - 8.7e-19 68.1 0.0 8.7e-19 68.1 0.0 2.0 2 1 0 2 2 2 1 p21-C-terminal region-binding protein COPI_C PF06957.11 CDJ61737.1 - 0.037 12.8 6.9 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus SMYLE_N PF18615.1 CDJ61737.1 - 0.04 13.5 5.6 0.051 13.1 5.6 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PNISR PF15996.5 CDJ61737.1 - 0.28 11.4 15.4 0.43 10.8 15.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Hamartin PF04388.12 CDJ61737.1 - 0.48 9.0 7.6 0.49 9.0 7.6 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 CDJ61737.1 - 2.2 7.6 19.4 3 7.1 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF5523 PF17661.1 CDJ61737.1 - 2.4 7.8 16.7 3.4 7.3 16.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) BUD22 PF09073.10 CDJ61737.1 - 3.3 7.0 31.0 4.7 6.4 31.0 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 CDJ61737.1 - 5.3 6.6 28.2 8.5 5.9 28.2 1.3 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.6 CDJ61737.1 - 8.3 5.0 11.1 11 4.6 11.1 1.1 1 0 0 1 1 1 0 Raftlin LigT_PEase PF02834.16 CDJ61738.1 - 0.11 12.7 0.4 2.4 8.4 0.4 3.6 1 0 0 1 1 1 0 LigT like Phosphoesterase NAM-associated PF14303.6 CDJ61738.1 - 8.1 7.1 0.0 8.1 7.1 0.0 10.5 8 3 2 10 10 10 0 No apical meristem-associated C-terminal domain DNA_pol_E_B PF04042.16 CDJ61739.1 - 6.5e-05 22.4 0.0 0.00031 20.2 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Eapp_C PF10238.9 CDJ61739.1 - 0.022 14.8 1.4 0.022 14.8 1.4 4.9 5 1 0 5 5 5 0 E2F-associated phosphoprotein DUF4667 PF15700.5 CDJ61739.1 - 0.078 13.1 23.9 0.022 14.9 4.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) Gar1 PF04410.14 CDJ61740.1 - 1.7e-06 27.9 0.1 6.4e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region SLATT_1 PF18181.1 CDJ61740.1 - 0.28 11.1 3.7 0.3 11.0 0.5 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 CDC45 PF02724.14 CDJ61740.1 - 4.4 5.5 19.1 0.11 10.7 12.8 1.4 2 0 0 2 2 2 0 CDC45-like protein CCDC106 PF15794.5 CDJ61741.1 - 1.4 8.6 5.3 2 8.1 5.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sporozoite_P67 PF05642.11 CDJ61741.1 - 1.6 6.8 10.2 1.7 6.6 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.29 CDJ61742.1 - 5.3e-32 111.0 0.0 5.3e-32 111.0 0.0 2.1 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PPL5 PF18168.1 CDJ61742.1 - 1.8e-05 24.2 1.2 3.3e-05 23.4 1.2 1.4 1 0 0 1 1 1 1 Prim-pol family 5 Presenilin PF01080.17 CDJ61742.1 - 0.0014 17.5 13.5 0.0015 17.4 13.5 1.1 1 0 0 1 1 1 1 Presenilin DUF572 PF04502.13 CDJ61742.1 - 0.0032 17.1 10.5 0.0038 16.9 10.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) CDC45 PF02724.14 CDJ61742.1 - 0.0038 15.6 9.2 0.0041 15.5 9.2 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.13 CDJ61742.1 - 0.043 13.8 45.2 0.059 13.4 45.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CDJ61742.1 - 0.081 12.9 10.7 0.12 12.4 10.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.12 CDJ61742.1 - 0.11 12.8 13.5 0.14 12.4 13.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.12 CDJ61742.1 - 0.12 11.7 22.6 0.2 11.0 22.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 CDJ61742.1 - 0.15 10.9 15.4 0.18 10.5 15.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EPL1 PF10513.9 CDJ61742.1 - 0.17 12.3 18.0 0.31 11.4 18.0 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DDHD PF02862.17 CDJ61742.1 - 0.18 11.9 12.5 0.25 11.4 12.5 1.3 1 0 0 1 1 1 0 DDHD domain Alpha-amylase PF00128.24 CDJ61742.1 - 0.2 11.2 9.1 0.26 10.8 9.1 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain AMP-binding PF00501.28 CDJ61742.1 - 0.4 9.2 2.9 0.56 8.7 2.9 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Asp-B-Hydro_N PF05279.11 CDJ61742.1 - 0.67 10.0 14.3 0.92 9.5 14.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NARP1 PF12569.8 CDJ61742.1 - 0.67 8.8 16.4 0.86 8.4 16.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CDJ61742.1 - 0.75 9.6 20.9 1 9.1 20.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CDJ61742.1 - 0.86 9.7 22.1 1.2 9.3 22.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SID-1_RNA_chan PF13965.6 CDJ61742.1 - 1.3 7.4 4.6 1.5 7.1 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Lin-8 PF03353.15 CDJ61742.1 - 1.3 8.5 24.1 1.8 8.1 24.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 CDJ61742.1 - 1.6 8.8 14.2 2.1 8.4 14.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 CDJ61742.1 - 1.6 7.6 19.2 2.1 7.2 19.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.6 CDJ61742.1 - 2 8.3 25.6 3.2 7.7 25.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.14 CDJ61742.1 - 2.1 8.3 22.5 0.8 9.6 19.3 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TetR_C_19 PF17924.1 CDJ61742.1 - 2.3 8.8 9.7 3.1 8.4 9.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TRAP_alpha PF03896.16 CDJ61742.1 - 2.9 7.0 11.4 4.1 6.5 11.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XRN_M PF17846.1 CDJ61742.1 - 3 6.7 12.6 3.9 6.3 12.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Membralin PF09746.9 CDJ61742.1 - 3.1 6.8 10.1 3.7 6.5 10.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Tim54 PF11711.8 CDJ61742.1 - 3.4 6.4 16.5 5 5.8 16.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.7 CDJ61742.1 - 3.4 5.7 19.8 4.2 5.4 19.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Exonuc_VII_L PF02601.15 CDJ61742.1 - 3.4 7.1 20.7 5.5 6.5 20.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 CDJ61742.1 - 3.6 6.3 15.1 4.5 6.0 15.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 CDJ61742.1 - 5 6.0 20.4 6.5 5.7 20.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 CDJ61742.1 - 5 5.9 15.5 6.8 5.5 15.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GBP_C PF02841.14 CDJ61742.1 - 5.3 6.4 30.4 7.9 5.8 30.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain YABBY PF04690.13 CDJ61742.1 - 6.1 7.4 14.8 9.7 6.7 14.8 1.3 1 0 0 1 1 1 0 YABBY protein DUF4746 PF15928.5 CDJ61742.1 - 7.5 5.9 16.2 11 5.4 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S64 PF08192.11 CDJ61742.1 - 9.6 4.5 15.4 12 4.3 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 MMR1 PF08505.10 CDJ61742.1 - 9.7 6.4 25.0 14 5.9 25.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AUX_IAA PF02309.16 CDJ61742.1 - 9.8 5.9 12.3 14 5.4 12.3 1.3 1 0 0 1 1 1 0 AUX/IAA family Ndc1_Nup PF09531.10 CDJ61742.1 - 9.8 4.7 21.7 13 4.4 21.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cnd1 PF12717.7 CDJ61743.1 - 0.062 13.3 0.0 0.091 12.8 0.0 1.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_1c PF00749.21 CDJ61745.1 - 1e-38 133.0 0.2 2.2e-21 76.1 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDJ61745.1 - 3.5e-33 114.9 0.0 4.9e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Caldesmon PF02029.15 CDJ61746.1 - 1.1e-05 24.4 34.8 2.2e-05 23.4 34.8 1.4 1 0 0 1 1 1 1 Caldesmon SPX PF03105.19 CDJ61746.1 - 0.00032 20.7 10.3 0.00032 20.7 10.3 2.2 2 0 0 2 2 2 1 SPX domain AIF_C PF14721.6 CDJ61746.1 - 0.00059 20.2 9.5 0.00059 20.2 9.5 3.9 2 1 2 4 4 4 1 Apoptosis-inducing factor, mitochondrion-associated, C-term BUD22 PF09073.10 CDJ61746.1 - 0.0015 18.0 32.3 0.0042 16.5 32.3 1.7 1 1 0 1 1 1 1 BUD22 SARAF PF06682.12 CDJ61746.1 - 0.0068 16.1 5.3 0.0068 16.1 5.3 3.4 1 1 1 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis GRP PF07172.11 CDJ61746.1 - 0.0096 16.6 0.2 0.0096 16.6 0.2 4.4 5 0 0 5 5 5 1 Glycine rich protein family HCO3_cotransp PF00955.21 CDJ61746.1 - 2.6 6.7 6.4 5.5 5.7 6.4 1.5 1 0 0 1 1 1 0 HCO3- transporter family Raftlin PF15250.6 CDJ61746.1 - 3 6.5 27.1 0.093 11.5 17.1 2.2 2 0 0 2 2 2 0 Raftlin Mpp10 PF04006.12 CDJ61746.1 - 3.1 6.1 49.2 5.6 5.3 49.2 1.4 1 1 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 CDJ61746.1 - 4.5 6.6 45.8 0.066 12.6 30.9 2.3 2 0 0 2 2 2 0 SDA1 DUF2040 PF09745.9 CDJ61747.1 - 9.8e-14 51.5 36.1 2e-12 47.2 12.1 3.6 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) MSP1_C PF07462.11 CDJ61747.1 - 0.0063 15.3 5.1 0.012 14.4 5.1 1.6 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Mic1 PF07035.12 CDJ61747.1 - 0.014 15.1 0.7 0.031 14.0 0.7 1.5 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like DUF908 PF06012.12 CDJ61747.1 - 1.4 8.2 14.0 0.11 11.9 8.7 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) S1 PF00575.23 CDJ61748.1 - 2.1e-05 24.8 1.2 0.21 12.0 0.0 3.4 2 1 0 2 2 2 2 S1 RNA binding domain SR-25 PF10500.9 CDJ61748.1 - 0.015 14.9 0.7 0.015 14.9 0.7 5.5 4 1 1 5 5 5 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDJ61748.1 - 0.11 12.9 18.9 0.25 11.7 5.5 4.1 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2722 PF10846.8 CDJ61749.1 - 3.1e-05 23.1 3.1 3.1e-05 23.1 3.1 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ61749.1 - 0.0029 17.2 10.6 0.0029 17.2 10.6 3.9 3 1 0 3 3 3 1 Spt20 family ABC2_membrane_2 PF12679.7 CDJ61749.1 - 0.015 14.6 0.2 0.015 14.6 0.2 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein EOS1 PF12326.8 CDJ61749.1 - 1.4 8.8 5.8 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 CDJ61752.1 - 0.00096 18.8 8.6 0.00096 18.8 8.6 3.1 3 0 0 3 3 3 2 Spt20 family RskA PF10099.9 CDJ61752.1 - 0.0026 18.1 29.8 0.38 11.0 18.1 3.3 2 1 1 3 3 3 2 Anti-sigma-K factor rskA DUF2722 PF10846.8 CDJ61752.1 - 0.0043 16.1 5.5 0.0043 16.1 5.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF2828 PF11443.8 CDJ61752.1 - 0.0092 14.1 0.1 0.017 13.2 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2828) CAF1 PF04857.20 CDJ61752.1 - 0.04 13.1 0.0 0.07 12.3 0.0 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease tRNA_lig_CPD PF08302.11 CDJ61752.1 - 0.14 11.6 7.0 0.24 10.8 0.1 2.3 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain MRP-63 PF14978.6 CDJ61752.1 - 0.42 11.2 10.5 0.057 14.0 3.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 eIF-3_zeta PF05091.12 CDJ61752.1 - 0.43 9.5 10.3 1.6 7.6 1.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 CDJ61752.1 - 0.92 7.9 4.6 5.4 5.4 0.1 2.2 2 0 0 2 2 2 0 FHIPEP family RPA43_OB PF17875.1 CDJ61752.1 - 1.2 9.8 7.1 5.6 7.6 0.1 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I DUF3464 PF11947.8 CDJ61752.1 - 2 8.2 9.5 5.4 6.7 0.1 2.9 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Reprolysin_3 PF13582.6 CDJ61752.1 - 2.5 8.6 6.2 8.9 6.9 0.2 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Rxt3 PF08642.10 CDJ61752.1 - 3.4 8.5 5.2 15 6.4 0.2 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Rsc14 PF08586.10 CDJ61752.1 - 3.9 8.3 10.7 1.6 9.6 3.3 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit CTNNB1_binding PF08347.11 CDJ61752.1 - 4.1 7.6 9.8 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 N-terminal CTNNB1 binding Rpp20 PF12328.8 CDJ61752.1 - 5.1 7.1 9.2 9.2 6.2 0.1 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P GDI PF00996.18 CDJ61754.1 - 1.4e-12 46.9 0.0 3e-06 26.0 0.0 3.2 3 0 0 3 3 3 3 GDP dissociation inhibitor MscS_TM PF12794.7 CDJ61754.1 - 0.021 13.7 0.0 0.021 13.7 0.0 3.0 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Tau95 PF09734.9 CDJ61755.1 - 7.5e-25 88.4 1.1 1.3e-21 77.9 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TFIIA PF03153.13 CDJ61755.1 - 0.00071 19.7 17.4 0.00071 19.7 17.4 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Tau95_N PF17682.1 CDJ61755.1 - 0.00088 19.5 2.3 0.2 11.9 0.0 3.5 3 1 0 3 3 3 1 Tau95 Triple barrel domain RskA PF10099.9 CDJ61756.1 - 1 9.7 0.0 1 9.7 0.0 12.0 3 3 3 7 7 7 0 Anti-sigma-K factor rskA Phi-29_GP16_7 PF06720.11 CDJ61757.1 - 0.079 12.8 0.5 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Baculo_PEP_C PF04513.12 CDJ61757.1 - 4.4 7.3 9.5 1.4 8.9 0.2 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC-like PF12805.7 CDJ61758.1 - 0.00025 20.2 10.3 0.00034 19.8 10.3 1.3 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Ureide_permease PF07168.11 CDJ61758.1 - 0.0022 16.8 0.9 0.0032 16.3 0.3 1.6 1 1 1 2 2 2 1 Ureide permease TFIIA PF03153.13 CDJ61758.1 - 0.08 12.9 24.0 0.1 12.6 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CDJ61758.1 - 0.084 12.4 11.6 0.11 12.0 11.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAA_hydrolase_N PF09298.11 CDJ61758.1 - 0.18 12.0 6.8 0.3 11.3 6.8 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal FapA PF03961.13 CDJ61758.1 - 5.6 5.5 7.6 6.6 5.2 7.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Kei1 PF08552.11 CDJ61758.1 - 7.3 6.4 9.3 0.97 9.3 4.1 1.9 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3300 PF11737.8 CDJ61758.1 - 9 5.8 18.5 13 5.2 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Secretin_N_2 PF07655.13 CDJ61759.1 - 0.017 15.6 9.6 0.017 15.6 9.6 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain TFIIA PF03153.13 CDJ61759.1 - 0.02 14.9 29.9 0.027 14.5 29.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ61759.1 - 0.034 14.1 17.7 0.051 13.5 17.7 1.3 1 0 0 1 1 1 0 SPX domain SBE2 PF17076.5 CDJ61759.1 - 0.25 9.5 11.9 0.28 9.4 11.9 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Rrn6 PF10214.9 CDJ61759.1 - 0.34 9.3 19.0 0.38 9.2 19.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AF-4 PF05110.13 CDJ61759.1 - 0.38 8.8 36.8 0.5 8.4 36.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOBP PF15279.6 CDJ61759.1 - 0.39 11.3 15.1 0.49 11.0 15.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FapA PF03961.13 CDJ61759.1 - 1.5 7.3 13.0 2.1 6.9 13.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hamartin PF04388.12 CDJ61759.1 - 1.8 7.2 21.6 2.2 6.8 21.6 1.1 1 0 0 1 1 1 0 Hamartin protein ALMT PF11744.8 CDJ61759.1 - 3.1 6.5 18.2 4.3 6.1 18.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Anoctamin PF04547.12 CDJ61759.1 - 5.2 5.8 6.1 6.8 5.4 6.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel MAGE PF01454.19 CDJ61760.1 - 0.014 15.1 2.5 0.023 14.4 2.5 1.4 1 0 0 1 1 1 0 MAGE family TFIIA PF03153.13 CDJ61760.1 - 0.086 12.8 30.4 0.11 12.5 30.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 CDJ61760.1 - 0.22 11.7 7.9 0.34 11.1 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Dfp1_Him1_M PF08630.10 CDJ61760.1 - 0.81 9.9 5.2 1.7 8.9 5.2 1.6 1 0 0 1 1 1 0 Dfp1/Him1, central region Activator_LAG-3 PF11498.8 CDJ61760.1 - 1.2 8.0 32.0 1.6 7.6 32.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Plasmodium_Vir PF05795.11 CDJ61760.1 - 1.2 8.4 2.6 1.3 8.3 2.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 CDJ61760.1 - 1.3 7.7 9.1 1.7 7.4 9.1 1.3 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ61760.1 - 2.4 8.2 5.1 3 7.8 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Allexi_40kDa PF05549.11 CDJ61760.1 - 2.5 7.6 6.2 3.8 6.9 6.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spt20 PF12090.8 CDJ61760.1 - 4.1 6.9 30.1 0.17 11.5 24.4 1.6 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.10 CDJ61760.1 - 7.4 5.1 36.1 13 4.4 36.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.7 CDJ61760.1 - 7.9 4.5 8.6 8.9 4.3 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 CDJ61761.1 - 1e-36 124.6 0.1 7.3e-07 28.9 0.0 8.5 7 1 0 7 7 7 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OmpH PF03938.14 CDJ61761.1 - 0.00053 20.3 26.2 0.00053 20.3 26.2 6.2 5 2 0 5 5 5 1 Outer membrane protein (OmpH-like) Apt1 PF10351.9 CDJ61761.1 - 0.0016 17.4 38.1 0.019 13.9 21.2 4.1 4 0 0 4 4 4 3 Golgi-body localisation protein domain Lin-8 PF03353.15 CDJ61761.1 - 0.026 14.1 58.9 0.12 11.9 31.6 4.2 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist RRM_occluded PF16842.5 CDJ61761.1 - 0.053 13.4 6.2 13 5.7 0.1 4.2 4 0 0 4 4 4 0 Occluded RNA-recognition motif MutS_III PF05192.18 CDJ61762.1 - 4.5e-14 53.1 0.0 7.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain III K_channel_TID PF07941.11 CDJ61762.1 - 0.038 14.5 3.4 0.038 14.5 3.4 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MMS19_N PF14500.6 CDJ61763.1 - 1.6e-10 41.1 0.1 1.6e-10 41.1 0.1 4.5 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II RskA PF10099.9 CDJ61763.1 - 0.0053 17.1 2.5 0.0053 17.1 2.5 10.3 3 3 4 7 7 7 2 Anti-sigma-K factor rskA tRNA_NucTransf2 PF09249.11 CDJ61763.1 - 0.016 15.5 0.0 0.071 13.4 0.0 2.2 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain TFIIA PF03153.13 CDJ61764.1 - 0.03 14.3 23.0 0.035 14.1 23.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nudc_N PF14050.6 CDJ61765.1 - 6.7e-20 70.8 0.0 1.3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Pox_A32 PF04665.12 CDJ61765.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.4 2 0 0 2 2 2 0 Poxvirus A32 protein Transketolase_C PF02780.20 CDJ61765.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain Ecl1 PF12855.7 CDJ61765.1 - 1.9 9.6 24.0 0.84 10.8 21.5 1.7 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins RAP1 PF07218.11 CDJ61765.1 - 3.6 5.7 7.9 4.4 5.5 7.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DRMBL PF07522.14 CDJ61766.1 - 5.8e-20 71.5 0.0 1.2e-19 70.5 0.0 1.6 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase SUIM_assoc PF16619.5 CDJ61766.1 - 0.0021 18.1 0.5 0.0021 18.1 0.5 2.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RMMBL PF07521.12 CDJ61766.1 - 0.0021 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain IHABP4_N PF16174.5 CDJ61766.1 - 0.45 11.1 8.8 0.87 10.2 8.8 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal FAM199X PF15814.5 CDJ61766.1 - 0.49 9.4 1.8 0.69 8.9 1.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF4179 PF13786.6 CDJ61766.1 - 1.1 9.8 2.8 3.7 8.1 2.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Ras PF00071.22 CDJ61767.1 - 9.8e-62 207.3 0.1 1.2e-61 207.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDJ61767.1 - 2.1e-35 121.5 0.0 3.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDJ61767.1 - 6.5e-14 51.8 0.0 8.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDJ61767.1 - 5.7e-06 26.4 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDJ61767.1 - 0.00019 21.0 0.0 0.00046 19.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDJ61767.1 - 0.00058 19.8 0.1 0.071 13.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CDJ61767.1 - 0.00061 19.2 0.1 0.0012 18.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CDJ61767.1 - 0.0028 17.4 0.1 0.0041 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDJ61767.1 - 0.0074 16.6 0.1 0.056 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CDJ61767.1 - 0.012 16.0 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 CDJ61767.1 - 0.033 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 CDJ61767.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 CDJ61767.1 - 0.068 13.2 0.1 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDJ61767.1 - 0.095 13.2 0.5 0.39 11.2 0.5 2.1 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CDJ61767.1 - 0.1 12.0 0.1 0.4 10.0 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein FAS_meander PF17951.1 CDJ61767.1 - 0.12 12.2 0.2 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain SNF2_N PF00176.23 CDJ61768.1 - 2.9e-63 213.7 0.9 6.2e-63 212.6 0.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDJ61768.1 - 1e-19 70.9 0.0 2.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDJ61768.1 - 2.3e-05 24.5 0.0 6.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CDJ61768.1 - 0.052 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 CDJ61768.1 - 0.27 9.9 10.2 0.48 9.0 10.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CDJ61768.1 - 0.36 9.1 14.7 0.92 7.7 14.7 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 CDJ61768.1 - 1.8 8.2 10.6 4.5 6.9 10.6 1.6 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GREB1 PF15782.5 CDJ61768.1 - 5.2 4.1 7.6 7.6 3.5 7.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP2C PF00481.21 CDJ61771.1 - 0.00092 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ING PF12998.7 CDJ61772.1 - 1.4e-06 28.8 0.1 3.5e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Apt1 PF10351.9 CDJ61772.1 - 0.065 12.1 23.5 0.21 10.4 11.4 2.6 3 0 0 3 3 3 0 Golgi-body localisation protein domain RskA PF10099.9 CDJ61774.1 - 6.4 7.0 75.6 9.8 6.4 19.1 5.5 1 1 2 3 3 3 0 Anti-sigma-K factor rskA DEAD_2 PF06733.15 CDJ61775.1 - 3.1e-18 66.0 2.8 3.1e-18 66.0 2.8 5.2 5 1 0 5 5 5 1 DEAD_2 SR-25 PF10500.9 CDJ61775.1 - 0.0052 16.4 4.8 0.0052 16.4 4.8 10.1 9 2 2 11 11 11 2 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 CDJ61776.1 - 7.7e-11 41.7 0.0 9.4e-10 38.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CDJ61776.1 - 0.043 13.8 6.7 0.052 13.5 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyoxalase_5 PF14696.6 CDJ61776.1 - 0.066 13.4 0.5 0.13 12.4 0.5 1.6 1 1 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF2062 PF09835.9 CDJ61776.1 - 1.1 9.2 5.2 2 8.2 5.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF726 PF05277.12 CDJ61776.1 - 5.9 5.7 7.5 9.8 5.0 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TFIIA PF03153.13 CDJ61777.1 - 0.025 14.6 22.8 0.13 12.3 2.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.6 CDJ61777.1 - 0.042 13.9 6.9 0.16 12.0 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Zip PF02535.22 CDJ61777.1 - 0.32 10.2 1.4 0.51 9.5 0.3 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 CDJ61777.1 - 0.39 10.8 6.4 4.5 7.3 0.2 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3292 PF11696.8 CDJ61777.1 - 2.9 6.2 7.9 0.29 9.5 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) MtN3_slv PF03083.16 CDJ61779.1 - 3e-09 36.8 0.5 3.9e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TFIIA PF03153.13 CDJ61779.1 - 0.24 11.4 25.4 0.35 10.8 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 CDJ61779.1 - 0.62 8.8 1.7 0.91 8.2 1.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 CDJ61779.1 - 7.1 5.5 4.8 11 4.9 4.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain AP2 PF00847.20 CDJ61780.1 - 2.9e-12 46.6 0.6 1.2e-11 44.6 0.6 2.1 1 0 0 1 1 1 1 AP2 domain WD40 PF00400.32 CDJ61781.1 - 1.6e-05 25.6 9.8 0.022 15.6 0.9 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_60s PF00428.19 CDJ61781.1 - 0.68 10.6 10.4 4.9 7.8 2.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Arm PF00514.23 CDJ61783.1 - 0.08 13.0 0.1 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DASH_Dad2 PF08654.10 CDJ61783.1 - 6 7.4 14.5 1.5 9.3 1.9 3.8 4 0 0 4 4 4 0 DASH complex subunit Dad2 SAS-6_N PF16531.5 CDJ61784.1 - 2.1e-27 95.5 3.0 3.6e-27 94.8 3.0 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal CSD PF00313.22 CDJ61784.1 - 0.042 13.7 0.2 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain TIP49 PF06068.13 CDJ61785.1 - 1.3e-158 527.8 0.0 1.6e-158 527.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDJ61785.1 - 9.9e-17 60.8 0.5 2e-15 56.7 0.5 2.9 1 1 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDJ61785.1 - 1.3e-12 48.3 0.0 1.7e-08 35.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDJ61785.1 - 2.6e-10 40.3 0.2 2.7e-07 30.5 0.1 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDJ61785.1 - 2.5e-06 27.8 0.0 0.083 13.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDJ61785.1 - 9.9e-06 25.6 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDJ61785.1 - 1.2e-05 25.7 0.0 0.0023 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 CDJ61785.1 - 0.00018 21.8 0.1 0.079 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDJ61785.1 - 0.00042 19.8 0.2 0.017 14.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDJ61785.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CDJ61785.1 - 0.00077 19.2 0.1 0.4 10.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 CDJ61785.1 - 0.0014 19.2 0.0 0.0044 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDJ61785.1 - 0.0031 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaB_C PF03796.15 CDJ61785.1 - 0.0034 16.7 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_7 PF12775.7 CDJ61785.1 - 0.0036 16.9 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDJ61785.1 - 0.0054 16.9 0.0 0.038 14.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 CDJ61785.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDJ61785.1 - 0.0075 16.3 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 CDJ61785.1 - 0.011 15.0 0.1 0.029 13.7 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 CDJ61785.1 - 0.011 15.7 0.0 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDJ61785.1 - 0.018 14.2 0.2 0.039 13.0 0.1 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CDJ61785.1 - 0.022 14.5 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 CDJ61785.1 - 0.023 13.9 0.0 1.8 7.7 0.0 2.5 2 1 0 2 2 2 0 PIF1-like helicase TsaE PF02367.17 CDJ61785.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDJ61785.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDJ61785.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CDJ61785.1 - 0.038 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 CDJ61785.1 - 0.044 13.7 0.3 0.14 12.0 0.0 2.0 2 1 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 CDJ61785.1 - 0.048 13.1 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CDJ61785.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Torsin PF06309.11 CDJ61785.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 CDJ61785.1 - 0.073 13.0 1.2 0.22 11.4 0.0 2.5 3 0 0 3 3 3 0 NTPase TniB PF05621.11 CDJ61785.1 - 0.086 12.2 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 CDJ61785.1 - 0.088 13.2 0.0 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glucosamine_iso PF01182.20 CDJ61786.1 - 5.4e-37 127.8 0.0 1e-36 127.0 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NAD_synthase PF02540.17 CDJ61786.1 - 0.13 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Exonuc_VII_L PF02601.15 CDJ61788.1 - 0.0037 16.9 1.5 0.04 13.5 1.5 2.5 1 1 0 1 1 1 1 Exonuclease VII, large subunit DUF2408 PF10303.9 CDJ61788.1 - 0.29 11.7 2.9 7.5 7.1 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) CDC37_N PF03234.14 CDJ61788.1 - 0.33 11.9 3.2 0.74 10.7 0.1 2.8 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding DUF2508 PF10704.9 CDJ61788.1 - 0.42 10.8 12.1 2.1 8.6 4.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) DUF5320 PF17253.2 CDJ61788.1 - 2.8 9.1 15.6 1.1 10.3 1.6 4.0 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Glyco_transf_28 PF03033.20 CDJ61788.1 - 9 6.3 7.4 1.4 9.0 0.0 3.3 4 0 0 4 4 4 0 Glycosyltransferase family 28 N-terminal domain RskA PF10099.9 CDJ61790.1 - 0.00023 21.5 6.5 0.00023 21.5 6.5 9.5 3 3 3 6 6 6 1 Anti-sigma-K factor rskA TPR_2 PF07719.17 CDJ61790.1 - 0.055 13.6 16.2 2.1 8.7 0.8 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDJ61790.1 - 6 7.1 15.2 11 6.3 0.3 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Kinesin PF00225.23 CDJ61791.1 - 1.1e-36 126.5 3.0 1.2e-24 86.9 0.2 3.6 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CDJ61791.1 - 3.1e-22 79.1 0.5 2.3e-17 63.3 0.2 2.3 2 0 0 2 2 2 2 Microtubule binding DUF2092 PF09865.9 CDJ61791.1 - 0.23 10.8 1.2 0.41 10.0 1.2 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) HMG_box PF00505.19 CDJ61792.1 - 4.9e-09 36.5 1.5 1.1e-08 35.4 1.0 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDJ61792.1 - 8.6e-08 32.7 6.7 6e-07 30.0 6.7 2.3 1 1 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 CDJ61792.1 - 3.5e-05 24.0 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Androgen_recep PF02166.16 CDJ61792.1 - 0.013 14.4 2.5 0.015 14.2 2.5 1.2 1 0 0 1 1 1 0 Androgen receptor DUF3987 PF13148.6 CDJ61792.1 - 0.015 14.3 3.4 0.024 13.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) OmpH PF03938.14 CDJ61792.1 - 0.055 13.8 14.5 0.1 12.9 14.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.17 CDJ61792.1 - 0.49 11.0 0.0 0.49 11.0 0.0 2.8 2 1 1 3 3 3 0 bZIP Maf transcription factor Pet100 PF09803.9 CDJ61792.1 - 0.5 10.9 2.8 1.1 9.9 2.8 1.7 1 0 0 1 1 1 0 Pet100 Spt20 PF12090.8 CDJ61792.1 - 1 8.9 14.8 1.6 8.3 14.8 1.3 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CDJ61792.1 - 2.2 8.2 3.8 3.1 7.8 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MscS_TM PF12794.7 CDJ61792.1 - 2.6 6.8 4.9 3.7 6.3 4.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-RanBP PF00641.18 CDJ61793.1 - 7.1e-05 22.0 2.6 7.1e-05 22.0 2.6 4.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others MIF4G PF02854.19 CDJ61794.1 - 5.2e-28 98.1 2.2 7.5e-28 97.6 2.2 1.2 1 0 0 1 1 1 1 MIF4G domain Spt20 PF12090.8 CDJ61795.1 - 0.00048 19.8 2.0 0.00059 19.5 2.0 1.2 1 0 0 1 1 1 1 Spt20 family DUF4667 PF15700.5 CDJ61795.1 - 0.0013 18.9 6.4 0.0019 18.3 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) TFIIA PF03153.13 CDJ61795.1 - 0.013 15.5 3.8 0.016 15.2 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CDJ61795.1 - 0.042 13.4 1.8 0.057 13.0 1.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 CDJ61795.1 - 0.086 12.7 3.3 0.1 12.5 3.3 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CDJ61795.1 - 0.1 11.5 3.7 0.12 11.2 3.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF412 PF04217.13 CDJ61795.1 - 0.36 10.7 3.8 0.52 10.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF4834 PF16118.5 CDJ61795.1 - 0.45 11.5 3.4 5.9 7.9 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AAR2 PF05282.11 CDJ61796.1 - 0.1 12.0 4.5 0.12 11.7 4.5 1.2 1 1 0 1 1 1 0 AAR2 protein Apt1 PF10351.9 CDJ61796.1 - 0.38 9.5 6.7 0.48 9.2 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDJ61796.1 - 0.92 7.8 4.6 1.4 7.2 4.6 1.2 1 0 0 1 1 1 0 Menin AAA_23 PF13476.6 CDJ61797.1 - 0.029 14.9 23.0 0.037 14.5 23.0 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 CDJ61797.1 - 0.15 11.6 22.4 0.23 11.0 22.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ61797.1 - 0.34 9.1 26.7 0.36 9.0 26.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAP1 PF07218.11 CDJ61797.1 - 1.1 7.5 19.4 1.3 7.2 19.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC27 PF09507.10 CDJ61797.1 - 1.4 8.2 32.7 1.6 8.0 32.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med15 PF09606.10 CDJ61797.1 - 1.7 7.2 41.0 2.1 6.9 41.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ALG3 PF05208.13 CDJ61798.1 - 0.068 12.6 0.2 0.086 12.3 0.2 1.1 1 0 0 1 1 1 0 ALG3 protein Pkinase PF00069.25 CDJ61799.1 - 2.4e-43 148.4 0.0 4.2e-43 147.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61799.1 - 2.7e-22 79.3 0.0 4.8e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDJ61799.1 - 0.0044 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDJ61799.1 - 0.0066 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 CDJ61799.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 CDJ61799.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 CDJ61799.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Imm51 PF15595.6 CDJ61800.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 51 DUF4698 PF15769.5 CDJ61801.1 - 0.00076 18.7 16.0 0.00076 18.7 16.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4698) Apt1 PF10351.9 CDJ61801.1 - 0.0017 17.3 22.5 0.0017 17.3 22.5 2.8 2 1 0 2 2 2 1 Golgi-body localisation protein domain SPX PF03105.19 CDJ61801.1 - 0.23 11.3 59.5 0.15 11.9 26.9 2.2 2 0 0 2 2 2 0 SPX domain AAA_23 PF13476.6 CDJ61801.1 - 0.29 11.6 25.3 0.68 10.4 14.7 2.4 2 1 0 2 2 2 0 AAA domain Presenilin PF01080.17 CDJ61801.1 - 2.2 6.9 51.1 0.04 12.7 9.2 3.1 3 0 0 3 3 3 0 Presenilin Senescence_reg PF04520.13 CDJ61802.1 - 1.4 9.7 15.2 2.5 8.9 15.2 1.4 1 0 0 1 1 1 0 Senescence regulator CCDC106 PF15794.5 CDJ61802.1 - 3.5 7.3 15.1 0.046 13.4 5.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 BBS2_C PF14782.6 CDJ61803.1 - 0.18 10.5 6.2 0.23 10.2 6.2 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal GREB1 PF15782.5 CDJ61803.1 - 4.8 4.2 9.5 6 3.8 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_60s PF00428.19 CDJ61803.1 - 7 7.3 21.8 5.1 7.7 14.7 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_C2 PF00648.21 CDJ61804.1 - 9.3e-30 103.7 3.0 3.3e-14 52.6 0.1 4.2 2 2 1 3 3 3 3 Calpain family cysteine protease PhyH PF05721.13 CDJ61806.1 - 1.8e-09 38.2 0.2 5.7e-06 26.7 0.0 2.9 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) DNA_pol_B PF00136.21 CDJ61807.1 - 1.4e-50 172.4 0.0 9e-47 159.8 0.0 3.2 2 1 1 3 3 3 2 DNA polymerase family B zf-C4pol PF14260.6 CDJ61807.1 - 0.00024 21.5 2.8 0.00024 21.5 2.8 3.5 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta PAM2 PF07145.15 CDJ61808.1 - 0.0018 17.8 0.2 0.0041 16.7 0.2 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region MRAP PF15183.6 CDJ61809.1 - 0.011 15.6 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family FAM176 PF14851.6 CDJ61809.1 - 7.9 6.1 11.7 9.8 5.8 0.1 2.3 2 0 0 2 2 2 0 FAM176 family Kinesin PF00225.23 CDJ61810.1 - 2e-103 345.9 0.0 3.1e-103 345.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDJ61810.1 - 5.5e-21 75.1 0.1 1.5e-20 73.7 0.1 1.7 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 CDJ61810.1 - 0.00027 21.3 0.0 0.0011 19.4 0.0 2.2 1 0 0 1 1 1 1 Kinesin protein 1B Kinesin_assoc PF16183.5 CDJ61810.1 - 0.00041 20.5 14.2 0.023 14.8 1.8 3.7 2 1 1 3 3 3 2 Kinesin-associated ORF6C PF10552.9 CDJ61810.1 - 0.64 10.1 7.0 0.64 10.1 2.5 2.9 2 1 0 2 2 2 0 ORF6C domain AAA_23 PF13476.6 CDJ61810.1 - 5.4 7.5 15.3 4.7 7.7 4.9 3.2 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 CDJ61810.1 - 8.7 4.8 13.3 4.9 5.7 6.9 2.1 2 0 0 2 2 2 0 AAA domain PKD_channel PF08016.12 CDJ61811.1 - 1e-11 44.2 33.8 4.4e-08 32.2 14.8 4.1 4 0 0 4 4 4 3 Polycystin cation channel AMP-binding PF00501.28 CDJ61812.1 - 2.7e-17 62.5 0.0 8e-15 54.4 0.0 3.6 2 1 0 2 2 2 2 AMP-binding enzyme zf-C2H2_2 PF12756.7 CDJ61813.1 - 4.8e-18 65.4 3.5 8.6e-18 64.5 2.5 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Mito_carr PF00153.27 CDJ61814.1 - 1.6e-57 191.4 4.6 1.1e-22 79.7 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF45 PF01863.17 CDJ61816.1 - 0.0002 21.5 1.2 0.00043 20.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF45 WLM PF08325.10 CDJ61816.1 - 2.6 8.1 9.0 0.053 13.6 0.9 2.4 2 1 0 2 2 2 0 WLM domain PKD_channel PF08016.12 CDJ61817.1 - 1.2e-08 34.1 32.5 1.1e-06 27.6 10.7 4.0 4 0 0 4 4 4 3 Polycystin cation channel Cullin PF00888.22 CDJ61818.1 - 3.8e-130 435.4 0.3 1e-129 434.0 0.3 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDJ61818.1 - 2.8e-22 78.5 0.4 1e-21 76.7 0.2 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF445 PF04286.12 CDJ61818.1 - 0.22 11.3 3.1 1.3 8.7 1.5 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF445) HU-CCDC81_euk_1 PF14908.6 CDJ61819.1 - 8.6e-18 64.3 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 CDJ61819.1 - 3.7e-14 52.6 0.1 7.2e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 CDJ61819.1 - 0.013 15.7 0.0 0.077 13.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial DNA-binding protein HU-HIG PF18291.1 CDJ61819.1 - 0.019 15.0 0.0 0.079 13.1 0.0 2.0 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif HTH_Tnp_1 PF01527.20 CDJ61820.1 - 0.0023 18.2 0.0 0.006 16.9 0.0 1.7 1 0 0 1 1 1 1 Transposase Bromodomain PF00439.25 CDJ61821.1 - 2.4e-12 46.8 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain BRF1 PF07741.13 CDJ61821.1 - 0.11 12.8 5.6 0.5 10.7 3.3 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TFIIA PF03153.13 CDJ61822.1 - 2.2 8.2 9.8 0.37 10.7 3.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CDJ61823.1 - 0.51 9.6 8.7 1 8.7 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 CDJ61823.1 - 1.7 8.8 11.7 0.39 11.0 5.9 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain LTXXQ PF07813.12 CDJ61825.1 - 0.014 16.1 0.1 0.016 15.9 0.1 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein RskA PF10099.9 CDJ61826.1 - 2.8e-07 31.0 11.2 3.3e-07 30.8 11.2 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CDJ61826.1 - 0.017 15.2 15.4 0.018 15.1 15.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TraT PF05818.12 CDJ61826.1 - 0.031 14.0 6.7 0.05 13.3 6.7 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF4179 PF13786.6 CDJ61826.1 - 0.033 14.7 1.7 0.061 13.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) EphA2_TM PF14575.6 CDJ61826.1 - 0.061 14.2 0.5 0.11 13.4 0.5 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.20 CDJ61826.1 - 0.11 11.0 4.5 0.13 10.7 4.5 1.0 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.6 CDJ61826.1 - 0.18 10.2 0.3 0.19 10.1 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM51 PF15345.6 CDJ61826.1 - 0.23 11.3 7.1 0.28 11.0 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ureide_permease PF07168.11 CDJ61826.1 - 0.26 10.0 1.7 0.29 9.8 1.7 1.2 1 0 0 1 1 1 0 Ureide permease Peptidase_C37 PF05416.12 CDJ61826.1 - 0.29 9.6 5.0 0.33 9.4 5.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase FAM176 PF14851.6 CDJ61826.1 - 0.39 10.4 6.8 0.55 9.9 6.8 1.2 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.17 CDJ61826.1 - 0.39 10.8 4.2 0.42 10.7 4.2 1.1 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.6 CDJ61826.1 - 0.45 10.4 14.1 0.49 10.3 14.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO 2HCT PF03390.15 CDJ61826.1 - 0.47 9.0 2.3 0.64 8.6 2.3 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family DUF4820 PF16091.5 CDJ61826.1 - 0.5 9.7 8.7 0.58 9.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 CDJ61826.1 - 0.54 11.3 7.9 0.82 10.7 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Myc_N PF01056.18 CDJ61826.1 - 0.55 10.1 8.9 0.68 9.8 8.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Paf1 PF03985.13 CDJ61826.1 - 0.74 8.7 12.2 0.76 8.7 12.2 1.1 1 0 0 1 1 1 0 Paf1 Spt20 PF12090.8 CDJ61826.1 - 0.81 9.2 21.0 1 8.9 21.0 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CDJ61826.1 - 1.6 7.8 17.3 2.5 7.2 17.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF775 PF05603.12 CDJ61826.1 - 1.8 8.1 9.2 2 7.9 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CLN3 PF02487.17 CDJ61826.1 - 2.2 7.2 3.3 2.6 7.0 3.3 1.1 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CDJ61826.1 - 2.7 6.6 8.9 3.1 6.5 8.9 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CDJ61826.1 - 3 6.7 4.7 3.3 6.5 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Connexin PF00029.19 CDJ61826.1 - 4.8 6.9 6.9 5.9 6.6 6.9 1.1 1 0 0 1 1 1 0 Connexin THOC2_N PF16134.5 CDJ61826.1 - 9.9 4.6 12.0 11 4.5 12.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DicB PF05358.11 CDJ61827.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 DicB protein RsfS PF02410.15 CDJ61828.1 - 0.027 14.9 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal silencing factor during starvation Ribosomal_60s PF00428.19 CDJ61828.1 - 4.1 8.0 9.1 2.8 8.6 5.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LMBR1 PF04791.16 CDJ61829.1 - 5 5.9 4.4 8 5.2 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GNAT_acetyltr_2 PF13718.6 CDJ61831.1 - 1.1e-54 185.3 8.9 6.2e-29 101.0 0.0 3.9 2 1 1 3 3 3 2 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CDJ61831.1 - 5e-16 59.1 19.3 2.2e-08 34.1 0.4 3.3 2 1 1 3 3 3 2 Possible tRNA binding domain Acetyltransf_1 PF00583.25 CDJ61831.1 - 0.00021 21.5 0.0 0.00099 19.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDJ61831.1 - 0.012 16.0 0.1 0.036 14.5 0.0 1.9 2 0 0 2 2 1 0 Acetyltransferase (GNAT) domain Ribosomal_60s PF00428.19 CDJ61831.1 - 0.031 14.9 7.9 0.031 14.9 7.9 5.8 4 1 1 5 5 3 0 60s Acidic ribosomal protein DUF3304 PF11745.8 CDJ61831.1 - 0.059 13.8 0.0 0.059 13.8 0.0 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF3304) DDHD PF02862.17 CDJ61831.1 - 0.36 10.9 6.5 0.064 13.4 1.6 2.1 2 0 0 2 2 2 0 DDHD domain PA26 PF04636.13 CDJ61831.1 - 0.69 8.8 5.1 1 8.2 5.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 CDJ61831.1 - 0.88 7.8 12.6 1.4 7.1 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein LCD1 PF09798.9 CDJ61831.1 - 1.3 7.4 6.3 2.2 6.7 6.3 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Rrn6 PF10214.9 CDJ61831.1 - 3.6 5.9 8.6 5.7 5.3 8.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Zip PF02535.22 CDJ61831.1 - 3.7 6.7 7.4 0.097 11.9 1.2 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Myc_N PF01056.18 CDJ61831.1 - 5 6.9 15.2 0.83 9.5 8.8 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF913 PF06025.12 CDJ61831.1 - 7.2 5.5 8.0 14 4.5 8.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCLC PF05934.11 CDJ61831.1 - 7.2 5.2 10.0 11 4.6 10.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4604 PF15377.6 CDJ61831.1 - 8.4 6.8 31.4 6.6 7.1 2.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) DUF3381 PF11861.8 CDJ61831.1 - 9 6.1 22.7 25 4.6 22.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2052 PF09747.9 CDJ61831.1 - 9.1 6.4 21.7 0.46 10.6 14.9 2.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Tam41_Mmp37 PF09139.11 CDJ61832.1 - 2.8e-37 128.9 0.0 5.6e-37 127.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial ACBP PF00887.19 CDJ61833.1 - 1.8e-19 69.7 3.6 2.7e-19 69.2 1.0 2.6 2 0 0 2 2 2 1 Acyl CoA binding protein TFIIA PF03153.13 CDJ61833.1 - 0.0065 16.5 14.1 0.0065 16.5 14.1 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CDJ61833.1 - 0.038 13.9 19.6 0.4 10.5 8.1 2.2 2 0 0 2 2 2 0 SPX domain WD40 PF00400.32 CDJ61834.1 - 1.1e-05 26.1 9.4 0.82 10.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ61834.1 - 0.0064 16.8 0.0 3.7 7.9 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Spc7 PF08317.11 CDJ61836.1 - 7.9e-05 21.7 5.7 7.9e-05 21.7 5.7 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein IFT57 PF10498.9 CDJ61836.1 - 9.1e-05 21.6 0.8 0.0026 16.8 0.9 2.0 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 AAA_13 PF13166.6 CDJ61836.1 - 0.011 14.4 0.9 0.016 13.9 0.9 1.1 1 0 0 1 1 1 0 AAA domain Yuri_gagarin PF15934.5 CDJ61836.1 - 0.016 15.1 3.4 0.024 14.5 3.4 1.2 1 0 0 1 1 1 0 Yuri gagarin EzrA PF06160.12 CDJ61836.1 - 0.022 13.0 1.6 0.033 12.4 1.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 CDJ61836.1 - 0.022 15.0 4.1 0.034 14.4 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 CDJ61836.1 - 0.026 13.8 4.8 0.039 13.2 4.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FAM184 PF15665.5 CDJ61836.1 - 0.15 11.8 4.2 0.21 11.3 4.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Atg14 PF10186.9 CDJ61836.1 - 0.15 11.1 4.1 0.26 10.3 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 CDJ61836.1 - 0.31 11.7 3.2 2.5 8.7 0.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HAUS-augmin3 PF14932.6 CDJ61836.1 - 0.34 10.4 6.5 0.19 11.3 2.5 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.11 CDJ61836.1 - 0.35 9.7 6.2 0.51 9.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pox_A_type_inc PF04508.12 CDJ61836.1 - 0.37 10.7 3.7 4 7.5 1.0 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.7 CDJ61836.1 - 0.46 10.6 6.5 0.98 9.6 6.5 1.6 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 CDJ61836.1 - 0.98 10.1 3.1 1.8 9.2 1.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 CDJ61836.1 - 1.1 9.4 5.3 3.7 7.6 4.1 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 CDJ61836.1 - 1.6 9.2 4.6 6.7 7.2 0.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SF1-HH PF16275.5 CDJ61837.1 - 0.35 11.2 3.9 14 6.1 0.9 2.6 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Sec63 PF02889.16 CDJ61839.1 - 3.6e-44 150.9 0.0 6.4e-44 150.0 0.0 1.4 1 1 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 CDJ61839.1 - 4.4e-06 27.0 0.0 1.4e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDJ61840.1 - 8.3e-20 71.3 0.0 2.1e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDJ61840.1 - 3.7e-05 23.8 0.0 0.00088 19.3 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDJ61840.1 - 0.00024 21.4 0.8 0.35 11.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CDJ61840.1 - 0.021 15.2 0.0 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cellulase PF00150.18 CDJ61841.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) FHIPEP PF00771.20 CDJ61841.1 - 0.3 9.5 3.4 0.43 9.0 3.4 1.3 1 0 0 1 1 1 0 FHIPEP family zf-RING_9 PF13901.6 CDJ61841.1 - 1.1 9.2 9.4 0.18 11.8 0.4 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon DUF2235 PF09994.9 CDJ61841.1 - 2.5 7.4 7.4 5.6 6.2 7.4 1.7 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Piezo_RRas_bdg PF12166.8 CDJ61841.1 - 2.6 7.2 7.5 3.6 6.8 7.5 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain ArAE_2_N PF10337.9 CDJ61841.1 - 5.5 5.9 5.9 8.2 5.3 5.9 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Ribosomal_L28 PF00830.19 CDJ61842.1 - 0.056 13.6 1.7 0.09 13.0 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L28 family Histone PF00125.24 CDJ61843.1 - 3.1e-10 40.5 3.9 1.7e-09 38.2 3.9 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 AAA_23 PF13476.6 CDJ61844.1 - 0.38 11.2 13.4 12 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Arm-DNA-bind_3 PF13356.6 CDJ61844.1 - 0.77 10.2 5.3 1 9.8 0.0 3.5 2 1 0 2 2 2 0 Arm DNA-binding domain SARAF PF06682.12 CDJ61844.1 - 2.3 7.8 11.8 1.8 8.1 4.4 2.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Gti1_Pac2 PF09729.9 CDJ61844.1 - 2.9 7.9 6.2 6.6 6.8 3.2 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Lin-8 PF03353.15 CDJ61844.1 - 4.3 6.8 16.7 5.7 6.4 10.7 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Rpr2 PF04032.16 CDJ61844.1 - 8.3 6.8 7.7 0.49 10.7 0.2 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Hydrolase_like PF13242.6 CDJ61845.1 - 0.00045 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 CDJ61845.1 - 0.011 15.3 0.3 0.011 15.3 0.3 3.1 3 1 0 3 3 3 0 Mitochondrial PGP phosphatase AAA_23 PF13476.6 CDJ61846.1 - 0.69 10.4 15.1 2.1 8.8 4.7 2.2 2 0 0 2 2 2 0 AAA domain PmbA_TldD PF01523.16 CDJ61846.1 - 4.8 6.9 8.7 6.8 6.4 8.7 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase RskA PF10099.9 CDJ61846.1 - 7.3 6.9 47.0 31 4.8 2.4 3.0 1 1 2 3 3 3 0 Anti-sigma-K factor rskA ULD PF16534.5 CDJ61848.1 - 0.038 14.0 1.1 0.41 10.7 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-like oligomerisation domain of SATB LRR_8 PF13855.6 CDJ61849.1 - 7.2e-10 38.5 30.4 0.00066 19.4 4.3 4.1 4 0 0 4 4 4 3 Leucine rich repeat DUF2722 PF10846.8 CDJ61849.1 - 0.001 18.1 5.0 0.001 18.1 5.0 23.3 15 6 5 20 20 20 3 Protein of unknown function (DUF2722) NAM-associated PF14303.6 CDJ61849.1 - 1.1 9.9 0.0 1.1 9.9 0.0 21.3 11 8 5 16 16 16 0 No apical meristem-associated C-terminal domain LRR_6 PF13516.6 CDJ61849.1 - 2.7 8.3 8.1 12 6.3 0.4 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 CDJ61849.1 - 3.6 8.2 36.1 0.17 12.3 1.5 5.3 4 2 1 6 6 6 0 Leucine Rich repeats (2 copies) RskA PF10099.9 CDJ61849.1 - 3.9 7.7 0.0 0.11 12.8 4.8 33.9 10 6 17 28 28 28 0 Anti-sigma-K factor rskA BPL_N PF09825.9 CDJ61850.1 - 1.1 8.2 3.5 1.8 7.5 3.5 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AP2 PF00847.20 CDJ61851.1 - 2.4e-10 40.5 0.2 2.4e-10 40.5 0.2 2.6 2 0 0 2 2 2 1 AP2 domain Auto_anti-p27 PF06677.12 CDJ61852.1 - 1.4e-06 28.3 0.5 2.7e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Auxin_canalis PF05703.11 CDJ61852.1 - 5.1e-05 23.3 7.2 6.2e-05 23.1 7.2 1.1 1 0 0 1 1 1 1 Auxin canalisation AAA_11 PF13086.6 CDJ61852.1 - 0.0035 17.2 9.9 0.0044 16.9 9.9 1.1 1 0 0 1 1 1 1 AAA domain OATP PF03137.20 CDJ61852.1 - 0.0045 15.3 1.3 0.0048 15.2 1.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Draxin PF15550.6 CDJ61852.1 - 0.0084 16.0 5.1 0.009 15.9 5.1 1.1 1 0 0 1 1 1 1 Draxin MTBP_C PF14920.6 CDJ61852.1 - 0.0086 15.8 7.0 0.0097 15.7 7.0 1.1 1 0 0 1 1 1 1 MDM2-binding TFIIA PF03153.13 CDJ61852.1 - 0.0087 16.1 24.2 0.01 15.9 24.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 CDJ61852.1 - 0.0092 15.4 8.2 0.011 15.2 8.2 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Asparaginase_2 PF01112.18 CDJ61852.1 - 0.0094 15.0 2.8 0.012 14.6 2.8 1.1 1 0 0 1 1 1 1 Asparaginase DUF853 PF05872.12 CDJ61852.1 - 0.012 14.3 6.1 0.014 14.1 6.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CPSF100_C PF13299.6 CDJ61852.1 - 0.016 15.4 4.2 0.018 15.3 4.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Glyco_transf_8 PF01501.20 CDJ61852.1 - 0.019 14.5 1.7 0.026 14.1 1.7 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 DDHD PF02862.17 CDJ61852.1 - 0.02 15.1 7.7 0.019 15.1 7.7 1.1 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 CDJ61852.1 - 0.02 14.7 6.2 0.023 14.5 6.2 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDJ61852.1 - 0.025 13.4 9.5 0.027 13.3 9.5 1.1 1 0 0 1 1 1 0 Presenilin MMM1 PF10296.9 CDJ61852.1 - 0.029 13.4 4.4 0.034 13.2 4.4 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Gti1_Pac2 PF09729.9 CDJ61852.1 - 0.032 14.3 5.8 0.036 14.1 5.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family GAGA_bind PF06217.12 CDJ61852.1 - 0.043 14.1 8.8 0.046 14.0 8.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIP PF07454.11 CDJ61852.1 - 0.061 12.8 10.2 0.074 12.5 10.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDJ61852.1 - 0.062 13.1 8.9 0.065 13.0 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HbrB PF08539.11 CDJ61852.1 - 0.066 13.2 3.1 0.084 12.9 3.1 1.2 1 0 0 1 1 1 0 HbrB-like GREB1 PF15782.5 CDJ61852.1 - 0.067 10.3 7.0 0.069 10.3 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF913 PF06025.12 CDJ61852.1 - 0.072 12.1 3.5 0.079 11.9 3.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mit_KHE1 PF10173.9 CDJ61852.1 - 0.075 13.1 7.0 0.085 12.9 7.0 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SLC12 PF03522.15 CDJ61852.1 - 0.076 12.0 9.6 0.085 11.9 9.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CDJ61852.1 - 0.077 13.3 5.3 0.093 13.0 5.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CobT PF06213.12 CDJ61852.1 - 0.078 12.4 14.6 0.1 12.0 14.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ABC2_membrane_2 PF12679.7 CDJ61852.1 - 0.082 12.2 2.5 0.12 11.7 2.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF775 PF05603.12 CDJ61852.1 - 0.082 12.4 8.8 0.1 12.1 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Neur_chan_memb PF02932.16 CDJ61852.1 - 0.092 12.8 7.7 0.1 12.6 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC53 PF10152.9 CDJ61852.1 - 0.095 13.1 11.3 0.14 12.6 11.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAT1 PF09770.9 CDJ61852.1 - 0.1 10.8 17.8 0.11 10.8 17.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3292 PF11696.8 CDJ61852.1 - 0.12 10.7 6.0 0.13 10.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4569 PF15133.6 CDJ61852.1 - 0.12 12.0 13.4 0.14 11.8 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) PIP5K PF01504.18 CDJ61852.1 - 0.14 11.4 7.1 0.16 11.2 7.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2072 PF09845.9 CDJ61852.1 - 0.15 12.3 5.9 0.2 11.9 5.9 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein Folate_carrier PF01770.18 CDJ61852.1 - 0.17 10.6 3.2 0.21 10.3 3.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier EOS1 PF12326.8 CDJ61852.1 - 0.18 11.7 4.3 0.23 11.4 4.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF2828 PF11443.8 CDJ61852.1 - 0.18 9.8 11.0 0.2 9.7 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Band_3_cyto PF07565.13 CDJ61852.1 - 0.2 11.5 8.3 0.23 11.2 8.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Membralin PF09746.9 CDJ61852.1 - 0.27 10.2 8.0 0.31 10.0 8.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein RED_N PF07808.13 CDJ61852.1 - 0.28 10.7 13.5 0.42 10.2 13.5 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region ALMT PF11744.8 CDJ61852.1 - 0.34 9.7 8.3 0.38 9.5 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4400 PF14348.6 CDJ61852.1 - 0.38 10.2 4.6 0.73 9.3 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) V_ATPase_I PF01496.19 CDJ61852.1 - 0.38 8.6 12.0 0.43 8.4 12.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PMI_typeI PF01238.21 CDJ61852.1 - 0.4 9.8 8.9 0.47 9.6 8.9 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I Sec62 PF03839.16 CDJ61852.1 - 0.41 10.1 7.6 0.47 9.9 7.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 BORG_CEP PF14957.6 CDJ61852.1 - 0.44 11.7 7.3 0.55 11.4 7.3 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF1980 PF09323.10 CDJ61852.1 - 0.45 10.4 7.4 0.56 10.1 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CLN3 PF02487.17 CDJ61852.1 - 0.47 9.4 11.1 0.63 9.0 11.1 1.1 1 0 0 1 1 1 0 CLN3 protein Cellulose_synt PF03552.14 CDJ61852.1 - 0.64 8.4 1.9 0.69 8.3 1.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Serinc PF03348.15 CDJ61852.1 - 0.66 8.8 5.3 0.85 8.5 5.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLPTM1 PF05602.12 CDJ61852.1 - 0.66 8.9 6.4 0.81 8.6 6.4 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) YABBY PF04690.13 CDJ61852.1 - 0.67 10.5 8.4 0.87 10.1 8.4 1.2 1 0 0 1 1 1 0 YABBY protein Mem_trans PF03547.18 CDJ61852.1 - 0.69 8.3 3.1 0.85 7.9 3.1 1.2 1 0 0 1 1 1 0 Membrane transport protein eIF-3_zeta PF05091.12 CDJ61852.1 - 0.73 8.7 15.6 0.82 8.6 15.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CDJ61852.1 - 0.85 8.2 7.6 0.9 8.1 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup KAsynt_C_assoc PF16197.5 CDJ61852.1 - 1 9.9 4.4 1.9 9.0 4.4 1.4 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Endonuc_Holl PF10107.9 CDJ61852.1 - 1 9.2 13.8 1.4 8.7 13.8 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PPL5 PF18168.1 CDJ61852.1 - 1.1 8.5 7.6 1.4 8.1 7.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Hid1 PF12722.7 CDJ61852.1 - 1.4 7.0 10.4 1.5 6.9 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.9 CDJ61852.1 - 1.5 7.3 22.7 1.8 6.9 22.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Folliculin PF11704.8 CDJ61852.1 - 1.8 8.4 10.4 2.4 8.0 10.4 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport GvpL_GvpF PF06386.11 CDJ61852.1 - 1.8 8.4 13.0 2.5 8.0 13.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1764 PF08576.10 CDJ61852.1 - 1.9 9.5 11.3 3.2 8.7 11.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.14 CDJ61852.1 - 2.1 6.5 13.0 2.6 6.2 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 CDJ61852.1 - 2.1 8.3 17.3 3.3 7.7 17.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 CDJ61852.1 - 2.3 8.9 25.1 5.1 7.7 25.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.10 CDJ61852.1 - 2.3 8.1 15.1 2.8 7.8 15.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit STAC2_u1 PF16664.5 CDJ61852.1 - 2.4 8.6 10.5 3.3 8.2 10.5 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 MDM10 PF12519.8 CDJ61852.1 - 2.4 6.9 10.2 2.8 6.7 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 VIR_N PF15912.5 CDJ61852.1 - 3 7.4 10.7 4 7.0 10.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CSG2 PF16965.5 CDJ61852.1 - 3.1 6.7 4.9 3.6 6.4 4.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Ctr PF04145.15 CDJ61852.1 - 3.3 8.3 6.3 4.9 7.8 6.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF3381 PF11861.8 CDJ61852.1 - 3.4 7.5 19.0 4.5 7.1 19.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SID-1_RNA_chan PF13965.6 CDJ61852.1 - 3.8 5.8 6.5 4.6 5.5 6.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4638 PF15472.6 CDJ61852.1 - 3.9 7.1 13.9 4.9 6.8 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FAM60A PF15396.6 CDJ61852.1 - 4.2 7.3 10.0 5.2 7.0 10.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DivIC PF04977.15 CDJ61852.1 - 8 6.3 25.6 7 6.5 10.7 2.2 2 0 0 2 2 2 0 Septum formation initiator RRM_1 PF00076.22 CDJ61853.1 - 1.6e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_EZ PF13513.6 CDJ61854.1 - 1.1e-05 25.8 6.9 2.9 8.5 0.1 7.3 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CDJ61854.1 - 0.00015 21.8 8.9 0.99 9.8 0.1 5.8 5 0 0 5 5 5 2 HEAT repeat IFRD PF05004.13 CDJ61854.1 - 0.0002 20.6 1.1 0.078 12.1 0.0 4.3 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 CDJ61854.1 - 0.0097 16.3 9.8 0.11 12.9 0.1 5.5 6 0 0 6 6 6 1 HEAT repeats Arm PF00514.23 CDJ61854.1 - 3.1 8.0 15.5 0.85 9.8 0.1 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4400 PF14348.6 CDJ61855.1 - 0.018 14.6 0.0 0.46 10.0 0.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) MOLO1 PF17175.4 CDJ61856.1 - 2.9e-25 88.7 0.0 4.2e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDJ61856.1 - 1.2e-07 32.0 0.0 8.1e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 TPM domain KH_2 PF07650.17 CDJ61857.1 - 0.023 14.5 0.2 0.036 13.9 0.1 1.6 1 1 1 2 2 2 0 KH domain PTH2 PF01981.16 CDJ61858.1 - 1.5e-17 63.9 0.1 2.4e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.32 CDJ61859.1 - 2.2e-09 37.8 0.2 2.7e-05 24.8 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ61859.1 - 0.0013 19.0 0.0 0.056 13.8 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDJ61859.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Telomere_Sde2_2 PF13297.6 CDJ61860.1 - 1.8e-16 59.5 1.9 1.9e-16 59.4 0.3 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 CDJ61860.1 - 4.1e-13 49.5 0.5 4.1e-13 49.5 0.5 3.4 2 2 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain RAP1 PF07218.11 CDJ61860.1 - 3.2 5.9 11.6 4.1 5.6 11.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IGPD PF00475.18 CDJ61861.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase MIP PF00230.20 CDJ61862.1 - 1.9e-17 63.7 12.1 1.1e-16 61.2 11.8 1.9 1 1 1 2 2 2 2 Major intrinsic protein SLBP_RNA_bind PF15247.6 CDJ61863.1 - 3.1e-23 81.7 1.9 7.9e-23 80.4 1.9 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Ribosomal_S8 PF00410.19 CDJ61864.1 - 4.5e-21 75.1 0.0 5.5e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Mito_carr PF00153.27 CDJ61865.1 - 8.5e-39 131.4 5.8 1.2e-15 57.2 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein V-SNARE_C PF12352.8 CDJ61866.1 - 1.1e-09 38.4 2.2 1.1e-09 38.4 2.2 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CDJ61866.1 - 9.2e-07 29.2 2.7 2.2e-06 28.0 0.0 2.5 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Nbl1_Borealin_N PF10444.9 CDJ61866.1 - 0.0011 18.6 0.1 0.34 10.6 0.0 2.8 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal LPD30 PF18850.1 CDJ61866.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 DUF3037 PF11236.8 CDJ61866.1 - 0.071 13.5 0.4 0.16 12.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) EF-hand_7 PF13499.6 CDJ61867.1 - 2.1e-10 40.9 3.2 1e-06 29.1 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDJ61867.1 - 5.1e-10 38.5 4.8 1.9e-07 30.4 0.1 4.5 5 1 1 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 CDJ61867.1 - 5.4e-09 35.0 6.0 4.1e-06 25.9 0.1 5.3 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.6 CDJ61867.1 - 3.8e-06 26.7 3.5 0.0013 18.6 0.2 3.9 3 2 0 4 4 4 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 CDJ61867.1 - 0.00017 21.6 0.0 0.05 13.7 0.0 2.9 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 CDJ61867.1 - 0.0066 16.8 0.0 0.12 12.7 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain DUF3008 PF11450.8 CDJ61867.1 - 0.033 14.4 0.2 0.083 13.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) EF-hand_5 PF13202.6 CDJ61867.1 - 0.23 11.0 2.9 5.9 6.6 0.1 3.4 3 0 0 3 3 3 0 EF hand cNMP_binding PF00027.29 CDJ61868.1 - 2.3e-17 62.8 0.0 6.3e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CDJ61868.1 - 0.17 11.1 10.5 0.26 10.5 10.5 1.2 1 0 0 1 1 1 0 Ion transport protein DEAD PF00270.29 CDJ61869.1 - 1.1e-41 142.5 0.0 2e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ61869.1 - 5.4e-16 58.9 0.0 4.7e-15 55.9 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain mIF3 PF14877.6 CDJ61869.1 - 0.014 15.1 1.1 0.032 13.9 1.1 1.6 1 0 0 1 1 1 0 Mitochondrial translation initiation factor SecA_DEAD PF07517.14 CDJ61869.1 - 0.039 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 SecA DEAD-like domain T3SS_basalb_I PF17001.5 CDJ61869.1 - 0.77 10.4 5.6 4.1 8.1 0.2 4.4 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cyt-b5 PF00173.28 CDJ61870.1 - 2.7e-22 78.7 0.1 4e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PspB PF06667.12 CDJ61870.1 - 0.065 13.3 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Phage shock protein B DUF4366 PF14283.6 CDJ61870.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DnaJ PF00226.31 CDJ61871.1 - 5.1e-15 55.3 0.0 5.1e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain RR_TM4-6 PF06459.12 CDJ61871.1 - 3 7.6 10.0 0.41 10.4 5.9 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S28 PF05577.12 CDJ61872.1 - 2.7e-30 105.5 9.9 1.5e-26 93.2 1.0 3.3 2 1 0 3 3 3 3 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDJ61872.1 - 0.0015 17.9 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Maelstrom PF13017.6 CDJ61872.1 - 0.028 14.1 0.3 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 piRNA pathway germ-plasm component DUF3474 PF11960.8 CDJ61872.1 - 0.21 11.8 2.5 0.19 12.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) DUF4698 PF15769.5 CDJ61872.1 - 0.65 9.0 16.4 0.045 12.8 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) Ipi1_N PF12333.8 CDJ61872.1 - 1.3 9.6 4.2 27 5.4 0.2 2.6 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Folliculin PF11704.8 CDJ61872.1 - 2.3 8.0 9.1 8.3 6.2 0.4 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Nipped-B_C PF12830.7 CDJ61872.1 - 6 6.8 10.6 7.6 6.4 0.4 2.7 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF3881 PF12997.7 CDJ61873.1 - 0.012 14.9 2.4 0.012 14.9 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Ly49 PF08391.10 CDJ61873.1 - 0.064 13.6 5.6 0.12 12.7 2.0 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region LapA_dom PF06305.11 CDJ61873.1 - 0.087 12.7 0.1 0.087 12.7 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PEARLI-4 PF05278.12 CDJ61873.1 - 0.093 12.3 6.3 1.5 8.3 2.2 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) eIF3_subunit PF08597.10 CDJ61873.1 - 0.67 9.8 12.7 1.3 8.9 12.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Miga PF10265.9 CDJ61873.1 - 4.1 6.2 16.7 1.5 7.7 8.5 2.0 2 0 0 2 2 2 0 Mitoguardin RRM_1 PF00076.22 CDJ61874.1 - 1.3e-15 56.9 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDJ61874.1 - 9.3e-11 41.9 0.0 3.9e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 SPOC domain RRM_occluded PF16842.5 CDJ61874.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 CDJ61874.1 - 0.05 13.3 0.2 0.083 12.5 0.2 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Pkinase PF00069.25 CDJ61876.1 - 8.4e-37 127.0 0.0 1e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDJ61876.1 - 3.4e-18 65.9 0.0 4.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDJ61876.1 - 4.8e-07 29.4 0.0 6.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDJ61876.1 - 5.7e-07 28.6 0.0 6.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDJ61876.1 - 6.3e-06 26.3 0.9 1.1e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDJ61876.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CDJ61876.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain AP2 PF00847.20 CDJ61877.1 - 5.9e-10 39.2 9.3 8.2e-09 35.6 7.9 3.1 2 0 0 2 2 2 1 AP2 domain AAA_23 PF13476.6 CDJ61877.1 - 1.7 9.1 57.2 1.6 9.2 3.3 3.5 3 0 0 3 3 3 0 AAA domain OB_RNB PF08206.11 CDJ61879.1 - 0.0066 16.1 0.1 0.0066 16.1 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain BAF1_ABF1 PF04684.13 CDJ61879.1 - 0.082 12.0 0.7 0.089 11.8 0.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GRP PF07172.11 CDJ61879.1 - 1.2 9.8 47.0 3.6 8.4 13.9 2.4 2 0 0 2 2 2 0 Glycine rich protein family SURF2 PF05477.11 CDJ61879.1 - 8.7 6.0 9.2 14 5.3 9.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2722 PF10846.8 CDJ61880.1 - 0.00018 20.6 3.1 0.00018 20.6 3.1 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 CDJ61880.1 - 0.00026 20.7 3.7 0.00026 20.7 3.7 3.5 3 0 0 3 3 3 1 Spt20 family DUF4813 PF16072.5 CDJ61880.1 - 0.0054 16.4 11.8 0.0054 16.4 11.8 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4813) DUF4834 PF16118.5 CDJ61880.1 - 0.25 12.3 11.2 0.21 12.6 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Peptidase_S49_N PF08496.10 CDJ61880.1 - 2.7 8.0 6.5 0.17 11.9 0.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EF-hand_7 PF13499.6 CDJ61881.1 - 6.7e-05 23.3 0.1 0.0002 21.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDJ61881.1 - 0.00016 21.0 0.1 0.0034 16.8 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDJ61881.1 - 0.00023 20.8 1.1 0.17 11.9 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain Vps62 PF06101.11 CDJ61881.1 - 0.0087 14.4 0.0 0.015 13.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_8 PF13833.6 CDJ61881.1 - 0.011 15.6 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CDJ61881.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 EF hand RskA PF10099.9 CDJ61883.1 - 0.019 15.3 2.4 0.019 15.3 2.4 6.5 1 1 4 5 5 5 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 CDJ61884.1 - 0.0021 18.6 12.8 0.0021 18.6 12.8 3.7 3 1 0 3 3 3 1 AAA domain PUFD PF16553.5 CDJ61885.1 - 0.0064 16.6 0.1 0.0084 16.2 0.1 1.2 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain ATP12 PF07542.11 CDJ61885.1 - 0.015 15.3 1.4 0.022 14.8 1.4 1.3 1 0 0 1 1 1 0 ATP12 chaperone protein NDUF_B5 PF09781.9 CDJ61885.1 - 0.024 14.2 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit CGI-121 PF08617.10 CDJ61885.1 - 0.025 14.7 0.6 0.032 14.4 0.6 1.1 1 0 0 1 1 1 0 Kinase binding protein CGI-121 SPOUT_MTase PF02590.17 CDJ61885.1 - 0.026 14.5 0.7 0.032 14.2 0.7 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase WASH-7_mid PF14744.6 CDJ61885.1 - 0.032 13.3 0.5 0.035 13.2 0.5 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 DUF3710 PF12502.8 CDJ61885.1 - 0.062 13.0 1.0 0.076 12.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) RskA PF10099.9 CDJ61887.1 - 2.5e-05 24.7 19.6 4.3e-05 23.9 5.9 3.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Sin_N PF04801.13 CDJ61887.1 - 0.015 14.5 19.0 0.021 14.0 19.0 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Spt20 PF12090.8 CDJ61887.1 - 0.037 13.6 39.3 0.13 11.8 12.7 2.1 2 0 0 2 2 2 0 Spt20 family Tox-WTIP PF15654.6 CDJ61887.1 - 0.37 11.2 0.2 0.37 11.2 0.2 2.8 4 0 0 4 4 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Presenilin PF01080.17 CDJ61887.1 - 0.42 9.3 9.2 0.6 8.8 9.2 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CDJ61887.1 - 1.2 8.1 7.9 1.5 7.7 7.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 CDJ61887.1 - 1.4 8.1 5.6 2.1 7.5 5.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Lin-8 PF03353.15 CDJ61887.1 - 1.8 8.1 16.9 2.5 7.6 16.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDJ61887.1 - 2.2 6.7 10.7 5.3 5.5 10.7 1.6 1 0 0 1 1 1 0 Macoilin family TERB2 PF15101.6 CDJ61887.1 - 6.8 6.7 17.3 5 7.1 4.5 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 CDJ61887.1 - 7.4 6.5 9.5 12 5.9 9.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 CDJ61888.1 - 0.0007 19.3 19.6 0.0007 19.3 19.6 2.7 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CDJ61888.1 - 0.0081 16.2 37.1 0.012 15.6 37.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Herpes_LMP1 PF05297.11 CDJ61888.1 - 0.046 12.9 2.7 0.096 11.9 2.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PPP4R2 PF09184.11 CDJ61888.1 - 0.091 12.3 18.7 0.14 11.8 18.7 1.2 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 CDJ61888.1 - 0.13 12.0 12.2 0.19 11.5 12.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RAP1 PF07218.11 CDJ61888.1 - 0.58 8.4 7.3 0.9 7.7 7.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Coilin_N PF15862.5 CDJ61888.1 - 0.73 9.6 20.7 0.032 14.0 5.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus FAM199X PF15814.5 CDJ61888.1 - 0.82 8.7 10.2 1.6 7.7 10.2 1.4 1 0 0 1 1 1 0 Protein family FAM199X PIEZO PF15917.5 CDJ61888.1 - 1 8.8 21.3 1.4 8.3 21.3 1.3 1 0 0 1 1 1 0 Piezo PGA2 PF07543.12 CDJ61888.1 - 1.7 8.6 15.5 3.6 7.6 1.6 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 AAA_11 PF13086.6 CDJ61888.1 - 2.1 8.0 17.4 3 7.5 17.4 1.2 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 CDJ61888.1 - 3 8.3 11.4 14 6.2 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Caldesmon PF02029.15 CDJ61888.1 - 3.7 6.2 26.1 4.8 5.8 26.1 1.1 1 0 0 1 1 1 0 Caldesmon Dala_Dala_lig_N PF01820.21 CDJ61888.1 - 6.2 7.3 7.6 2.3e+02 2.3 7.6 2.8 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Hid1 PF12722.7 CDJ61888.1 - 6.3 4.8 19.1 9.1 4.3 19.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein rRNA_processing PF08524.11 CDJ61888.1 - 7.2 6.6 31.9 0.83 9.7 12.3 2.2 2 0 0 2 2 2 0 rRNA processing SLC12 PF03522.15 CDJ61888.1 - 9.7 5.1 20.1 41 3.0 21.2 1.5 2 0 0 2 2 2 0 Solute carrier family 12 EF-hand_1 PF00036.32 CDJ61890.1 - 4.2e-14 51.0 0.7 9.2e-08 31.1 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDJ61890.1 - 5.4e-12 44.6 0.3 4.7e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDJ61890.1 - 5.5e-11 42.8 0.4 7.5e-11 42.3 0.4 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDJ61890.1 - 2.9e-05 23.8 0.2 0.0005 19.9 0.0 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDJ61890.1 - 0.0071 16.7 0.0 0.0087 16.4 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain DUF2857 PF11198.8 CDJ61890.1 - 0.035 13.9 0.1 0.066 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2857) EF-hand_10 PF14788.6 CDJ61890.1 - 0.062 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 CDJ61890.1 - 0.073 13.0 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CDJ61890.1 - 0.11 12.0 0.1 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 EF hand DUF2722 PF10846.8 CDJ61891.1 - 0.0021 17.1 10.9 0.0021 17.1 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CREPT PF16566.5 CDJ61891.1 - 0.0073 16.5 11.9 0.013 15.6 9.3 2.1 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF2228 PF10228.9 CDJ61891.1 - 0.022 14.5 3.8 0.028 14.1 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) FAM76 PF16046.5 CDJ61891.1 - 0.022 14.1 8.7 0.03 13.7 8.7 1.1 1 0 0 1 1 1 0 FAM76 protein DivIC PF04977.15 CDJ61891.1 - 0.067 13.0 17.9 0.23 11.2 12.6 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF2464 PF10240.9 CDJ61891.1 - 0.087 12.4 3.2 0.1 12.2 3.2 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 FliD_C PF07195.12 CDJ61891.1 - 0.097 12.1 9.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Gastrin PF00918.17 CDJ61891.1 - 0.098 13.6 7.6 0.045 14.7 5.1 1.7 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF3450 PF11932.8 CDJ61891.1 - 0.12 11.6 18.7 0.38 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1764 PF08576.10 CDJ61891.1 - 0.12 13.2 4.4 0.25 12.3 4.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Presenilin PF01080.17 CDJ61891.1 - 0.3 9.8 2.7 0.29 9.9 2.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CDJ61891.1 - 0.38 10.8 3.0 0.41 10.7 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 CDJ61891.1 - 0.4 9.6 32.5 0.51 9.3 32.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CCDC-167 PF15188.6 CDJ61891.1 - 0.66 10.3 6.5 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MMR1 PF08505.10 CDJ61891.1 - 0.91 9.8 15.9 1.1 9.5 16.0 1.2 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Spc24 PF08286.11 CDJ61891.1 - 1.2 9.4 10.9 7 7.0 6.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 CDJ61891.1 - 1.5 7.6 4.7 1.8 7.3 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein OmpH PF03938.14 CDJ61891.1 - 1.6 9.1 25.1 3.3 8.0 21.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EIIBC-GUT_N PF03612.14 CDJ61891.1 - 1.6 8.4 4.6 2.5 7.8 4.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_lid_9 PF17871.1 CDJ61891.1 - 2.5 8.1 9.1 43 4.1 8.1 2.2 2 0 0 2 2 2 0 AAA lid domain SprA-related PF12118.8 CDJ61891.1 - 3.6 6.6 17.6 5.4 6.1 17.6 1.2 1 0 0 1 1 1 0 SprA-related family DUF1043 PF06295.12 CDJ61891.1 - 5.5 7.0 23.0 4.3 7.4 19.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FUSC PF04632.12 CDJ61891.1 - 8.5 4.8 11.1 13 4.2 11.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIP5K PF01504.18 CDJ61892.1 - 1.9e-56 191.3 25.8 1.5e-24 86.7 0.0 4.9 4 0 0 4 4 4 3 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 CDJ61893.1 - 8 6.3 70.1 0.0079 16.2 28.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Elf1 PF05129.13 CDJ61895.1 - 8.6e-14 51.4 4.4 7.8e-09 35.5 1.6 3.0 1 1 1 2 2 2 2 Transcription elongation factor Elf1 like IF4E PF01652.18 CDJ61896.1 - 1.4e-34 119.2 0.1 1.8e-34 118.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SR-25 PF10500.9 CDJ61897.1 - 0.0082 15.8 22.8 0.0082 15.8 22.8 5.7 4 1 1 5 5 5 3 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 CDJ61898.1 - 0.0045 16.1 1.2 0.0066 15.5 1.2 1.2 1 0 0 1 1 1 1 CLN3 protein RR_TM4-6 PF06459.12 CDJ61898.1 - 0.018 14.9 9.6 0.024 14.5 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 CDJ61898.1 - 0.19 11.6 2.3 0.26 11.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.6 CDJ61898.1 - 0.19 10.1 1.0 0.21 10.0 1.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 CDJ61898.1 - 0.94 8.3 2.9 1.1 8.1 2.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CDJ61898.1 - 1.2 7.9 14.9 1.7 7.3 14.9 1.2 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 CDJ61898.1 - 7.2 7.8 11.7 4 8.6 9.6 1.7 2 0 0 2 2 2 0 Cdc42 effector Connexin PF00029.19 CDJ61898.1 - 8 6.1 10.9 10 5.8 10.9 1.1 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 CDJ61898.1 - 8.7 6.3 8.5 13 5.8 8.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 CDJ61899.1 - 0.0025 17.5 16.8 0.0025 17.5 16.8 7.3 3 2 4 7 7 7 2 Nuclear RNA-splicing-associated protein RskA PF10099.9 CDJ61899.1 - 0.13 12.6 0.0 0.13 12.6 0.0 6.8 2 2 2 4 4 4 0 Anti-sigma-K factor rskA Cwf_Cwc_15 PF04889.12 CDJ61899.1 - 3.9 7.1 55.5 0.011 15.5 7.3 3.8 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PE_PPE_C PF12484.8 CDJ61901.1 - 0.59 11.1 27.1 5.1 8.1 13.2 2.7 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Hamartin PF04388.12 CDJ61901.1 - 4.2 5.9 31.5 6.7 5.2 31.5 1.3 1 0 0 1 1 1 0 Hamartin protein Glyco_tranf_2_3 PF13641.6 CDJ61902.1 - 0.4 10.5 7.3 2.5 7.9 0.2 3.3 3 1 1 4 4 4 0 Glycosyltransferase like family 2 Fibrillarin PF01269.17 CDJ61903.1 - 4.9e-99 330.0 0.0 5.6e-99 329.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CDJ61903.1 - 0.00033 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CDJ61903.1 - 0.063 13.0 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CDJ61903.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 CDJ61903.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 CDJ61903.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase NUDIX-like PF09296.11 CDJ61903.1 - 0.14 12.8 0.0 1.7 9.3 0.0 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase-like rudimentary NUDIX domain Methyltransf_31 PF13847.6 CDJ61903.1 - 0.2 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Caldesmon PF02029.15 CDJ61905.1 - 0.0072 15.2 54.4 0.079 11.7 23.3 2.1 2 0 0 2 2 2 2 Caldesmon T2SSM PF04612.12 CDJ61905.1 - 0.51 10.4 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M BAF1_ABF1 PF04684.13 CDJ61905.1 - 7.9 5.4 28.4 0.41 9.6 8.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Clat_adaptor_s PF01217.20 CDJ61906.1 - 2.2e-26 92.5 4.8 1.6e-25 89.7 4.8 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Hamartin PF04388.12 CDJ61907.1 - 0.0013 17.5 16.5 0.0013 17.5 16.5 4.2 2 1 2 4 4 4 1 Hamartin protein SR-25 PF10500.9 CDJ61907.1 - 0.0019 17.8 6.9 0.0019 17.8 6.9 9.6 6 3 4 10 10 10 3 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 CDJ61907.1 - 0.0089 16.1 3.2 0.0089 16.1 3.2 17.3 7 3 6 13 13 13 3 Unstructured region C-term to UIM in Ataxin3 cNMP_binding PF00027.29 CDJ61909.1 - 3.4e-20 71.9 0.0 5.3e-10 39.2 0.0 3.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DNA_photolyase PF00875.18 CDJ61909.1 - 0.41 10.6 4.3 0.17 11.9 0.8 2.2 2 0 0 2 2 2 0 DNA photolyase FapA PF03961.13 CDJ61909.1 - 0.75 8.3 23.2 1.1 7.8 9.2 3.2 2 1 1 3 3 3 0 Flagellar Assembly Protein A Spt20 PF12090.8 CDJ61911.1 - 8.4e-07 28.8 57.4 0.0081 15.8 13.1 3.4 3 0 0 3 3 3 3 Spt20 family RskA PF10099.9 CDJ61911.1 - 0.0033 17.8 0.0 0.0033 17.8 0.0 6.0 2 2 2 4 4 4 2 Anti-sigma-K factor rskA SARAF PF06682.12 CDJ61911.1 - 0.13 11.9 0.1 0.13 11.9 0.1 4.6 3 3 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Sin_N PF04801.13 CDJ61911.1 - 3.4 6.8 36.0 1.2 8.3 23.7 2.7 3 1 0 3 3 3 0 Sin-like protein conserved region MecA PF05389.12 CDJ61911.1 - 7.7 6.1 15.3 1.8 8.1 1.9 3.3 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) FAM199X PF15814.5 CDJ61912.1 - 0.0043 16.2 4.2 0.0043 16.2 4.2 2.3 3 0 0 3 3 3 1 Protein family FAM199X Chromo PF00385.24 CDJ61913.1 - 5.5e-05 23.0 0.3 0.00014 21.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UPF0242 PF06785.11 CDJ61915.1 - 0.46 10.6 33.8 0.53 10.4 33.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PPL5 PF18168.1 CDJ61915.1 - 1.1 8.5 8.3 1.2 8.3 8.3 1.0 1 0 0 1 1 1 0 Prim-pol family 5 ABC2_membrane_3 PF12698.7 CDJ61915.1 - 2.6 7.1 5.3 2.6 7.1 5.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 CDJ61916.1 - 1.1e-10 41.8 6.1 0.0004 21.1 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDJ61916.1 - 0.0023 18.2 0.0 0.67 10.3 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CDJ61916.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Presenilin PF01080.17 CDJ61916.1 - 0.22 10.3 0.0 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Presenilin MFS_1 PF07690.16 CDJ61917.1 - 2.2e-15 56.5 21.8 5.8e-15 55.1 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.15 CDJ61917.1 - 0.007 16.6 1.3 0.007 16.6 1.3 3.4 3 1 1 4 4 4 1 Uncharacterised BCR, YnfA/UPF0060 family PulG PF11773.8 CDJ61917.1 - 0.2 11.5 0.0 0.57 10.1 0.0 1.7 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DAD PF02109.16 CDJ61917.1 - 2 8.8 10.0 0.53 10.6 5.3 2.6 2 1 0 2 2 2 0 DAD family YqaH PF17448.2 CDJ61918.1 - 0.13 12.5 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized YqaH-like Ribosomal_L35p PF01632.19 CDJ61919.1 - 0.063 13.8 0.5 11 6.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L35 Cpn60_TCP1 PF00118.24 CDJ61920.1 - 5.9e-46 157.1 0.1 1.1e-45 156.2 0.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 CDJ61920.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 PcfK-like protein DUF778 PF05608.12 CDJ61921.1 - 0.18 12.2 3.9 0.79 10.1 3.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Activator_LAG-3 PF11498.8 CDJ61922.1 - 0.0093 15.0 8.9 0.011 14.8 8.9 1.0 1 0 0 1 1 1 1 Transcriptional activator LAG-3 GRP PF07172.11 CDJ61922.1 - 0.052 14.2 5.5 0.076 13.7 5.5 1.3 1 0 0 1 1 1 0 Glycine rich protein family Spt20 PF12090.8 CDJ61922.1 - 0.069 12.7 6.5 0.073 12.7 6.5 1.1 1 0 0 1 1 1 0 Spt20 family zf-HC5HC2H_2 PF13832.6 CDJ61923.1 - 5.9e-19 68.3 8.0 3.5e-06 27.1 0.0 4.7 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDJ61923.1 - 3.7e-06 27.1 1.5 3.7e-06 27.1 1.5 4.3 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CDJ61923.1 - 1.2e-05 24.7 0.7 1.2e-05 24.7 0.7 3.4 3 0 0 3 3 3 1 PHD-finger TUDOR_5 PF18359.1 CDJ61923.1 - 0.00043 19.9 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF2656 PF10847.8 CDJ61923.1 - 0.56 10.3 5.6 2.2 8.4 1.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2656) zf-UDP PF14569.6 CDJ61923.1 - 3.1 8.0 4.6 0.72 10.0 0.9 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger SelP_N PF04592.14 CDJ61923.1 - 5.4 6.3 6.8 5.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Draxin PF15550.6 CDJ61924.1 - 0.17 11.7 2.2 0.36 10.7 2.2 1.5 1 0 0 1 1 1 0 Draxin Ipi1_N PF12333.8 CDJ61926.1 - 0.05 14.2 0.2 0.05 14.2 0.2 2.5 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Exonuc_VII_L PF02601.15 CDJ61926.1 - 0.35 10.4 18.7 1.9 8.0 1.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PAT1 PF09770.9 CDJ61926.1 - 1.9 6.7 47.8 1.2 7.3 28.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 CDJ61926.1 - 2 8.5 25.8 0.64 10.1 2.2 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Band_3_cyto PF07565.13 CDJ61926.1 - 5.1 6.8 12.5 3.2 7.5 0.7 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CDJ61926.1 - 5.5 5.6 19.5 0.33 9.7 0.6 2.1 2 0 0 2 2 2 0 Presenilin DUF5568 PF17724.1 CDJ61926.1 - 7.2 6.4 7.2 0.5 10.1 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5568) RRM_1 PF00076.22 CDJ61928.1 - 9.2e-08 31.8 0.0 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cut8 PF08559.10 CDJ61928.1 - 0.019 14.6 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Activator_LAG-3 PF11498.8 CDJ61929.1 - 0.22 10.4 26.7 0.35 9.8 26.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3292 PF11696.8 CDJ61929.1 - 0.52 8.6 6.4 0.65 8.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TFIIA PF03153.13 CDJ61929.1 - 0.6 10.0 22.5 0.93 9.4 22.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 CDJ61929.1 - 2 7.4 12.4 2.7 6.9 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MAP65_ASE1 PF03999.12 CDJ61929.1 - 2.8 6.5 14.3 4.1 6.0 14.3 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Peptidase_S64 PF08192.11 CDJ61929.1 - 3.5 6.0 22.6 1.1 7.6 14.2 2.1 2 0 0 2 2 2 0 Peptidase family S64 RIFIN PF02009.16 CDJ61929.1 - 8.7 6.1 9.0 12 5.6 9.0 1.2 1 0 0 1 1 1 0 Rifin COP-gamma_platf PF08752.10 CDJ61930.1 - 5.1e-12 46.2 0.0 2.1e-10 40.9 0.0 2.9 2 1 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain GIDA_assoc PF13932.6 CDJ61930.1 - 5 7.3 9.2 2.6 8.2 7.4 1.5 2 0 0 2 2 2 0 GidA associated domain Presenilin PF01080.17 CDJ61930.1 - 6.4 5.4 7.5 8.7 5.0 7.5 1.2 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CDJ61930.1 - 9.9 5.0 17.5 0.14 11.1 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) COX14 PF14880.6 CDJ61931.1 - 6.1e-07 29.2 0.6 9e-07 28.7 0.6 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly SR-25 PF10500.9 CDJ61931.1 - 0.058 13.0 1.9 0.074 12.7 1.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ61931.1 - 0.095 13.0 3.7 0.13 12.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MAGE_N PF12440.8 CDJ61931.1 - 0.49 11.1 7.0 0.71 10.6 7.0 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SDA1 PF05285.12 CDJ61932.1 - 0.44 9.9 44.8 0.021 14.3 16.9 2.8 3 0 0 3 3 3 0 SDA1 FAM60A PF15396.6 CDJ61932.1 - 0.49 10.4 38.3 1.8 8.5 16.6 3.3 3 0 0 3 3 3 0 Protein Family FAM60A Nop14 PF04147.12 CDJ61932.1 - 2.7 6.1 41.9 0.87 7.7 11.2 2.9 3 0 0 3 3 3 0 Nop14-like family Mem_trans PF03547.18 CDJ61932.1 - 5.2 5.4 14.8 0.0063 15.0 1.7 2.2 2 0 0 2 2 2 0 Membrane transport protein ABC_tran PF00005.27 CDJ61933.1 - 1.4e-07 32.1 0.7 3e-07 31.0 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDJ61933.1 - 0.003 17.4 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CDJ61933.1 - 0.005 17.1 0.0 0.005 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CDJ61933.1 - 0.0054 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDJ61933.1 - 0.0097 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDJ61933.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CDJ61933.1 - 0.048 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDJ61933.1 - 0.054 13.5 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 CDJ61933.1 - 0.054 14.0 3.5 0.62 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CDJ61933.1 - 0.097 12.6 0.5 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 CDJ61933.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 CDJ61933.1 - 0.42 9.6 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PseudoU_synth_2 PF00849.22 CDJ61934.1 - 3.4e-05 24.0 0.0 0.00014 22.0 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CDJ61934.1 - 0.00013 21.6 0.1 0.0003 20.4 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_60s PF00428.19 CDJ61934.1 - 0.043 14.4 1.7 0.11 13.1 1.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peroxin-3 PF04882.12 CDJ61934.1 - 0.091 11.7 5.3 0.17 10.9 5.3 1.3 1 0 0 1 1 1 0 Peroxin-3 Presenilin PF01080.17 CDJ61934.1 - 0.31 9.8 2.7 0.43 9.3 2.7 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 CDJ61934.1 - 2 6.7 4.5 2.7 6.2 4.5 1.1 1 0 0 1 1 1 0 Menin Steroid_dh PF02544.16 CDJ61935.1 - 1.6e-36 125.5 3.9 1.6e-36 125.5 3.9 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.10 CDJ61935.1 - 0.011 16.4 0.0 0.021 15.5 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD EB1 PF03271.17 CDJ61938.1 - 3.2e-12 46.5 0.0 3.2e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 CDJ61938.1 - 3.1e-05 24.1 0.3 5.1e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Dsh_C PF12316.8 CDJ61938.1 - 0.018 15.4 4.2 0.026 14.9 4.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TFIIA PF03153.13 CDJ61938.1 - 0.12 12.3 15.0 0.17 11.9 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTZ PF03867.14 CDJ61938.1 - 0.63 9.5 6.5 0.86 9.1 6.5 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Spt20 PF12090.8 CDJ61938.1 - 1.6 8.3 18.8 2.5 7.7 18.8 1.2 1 0 0 1 1 1 0 Spt20 family AAA PF00004.29 CDJ61939.1 - 1.1e-14 55.0 0.4 3.9e-14 53.2 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDJ61939.1 - 0.00018 21.2 1.0 0.78 9.6 0.0 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_33 PF13671.6 CDJ61939.1 - 0.00028 21.1 0.1 0.0083 16.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 CDJ61939.1 - 0.0086 16.5 0.0 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDJ61939.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 CDJ61939.1 - 0.079 12.7 0.0 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 CDJ61939.1 - 0.23 11.4 2.9 6.9 6.6 1.5 3.6 1 1 1 2 2 2 0 NACHT domain AAA_22 PF13401.6 CDJ61939.1 - 1.4 9.2 5.4 2.8 8.2 0.1 3.2 2 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CDJ61939.1 - 5.8 7.3 19.3 0.2 12.0 1.6 4.7 4 2 1 5 5 5 0 AAA ATPase domain Virul_Fac PF10139.9 CDJ61939.1 - 8.6 4.4 7.4 0.25 9.5 0.2 2.0 2 0 0 2 2 2 0 Putative bacterial virulence factor F-box PF00646.33 CDJ61940.1 - 0.0017 18.2 4.2 0.0035 17.2 4.2 1.6 1 0 0 1 1 1 1 F-box domain Macoilin PF09726.9 CDJ61940.1 - 0.015 13.9 16.7 0.033 12.8 16.7 1.6 1 0 0 1 1 1 0 Macoilin family ABC2_membrane_3 PF12698.7 CDJ61940.1 - 0.2 10.8 0.2 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 CDJ61940.1 - 0.33 11.4 7.4 0.5 10.8 7.4 1.3 1 0 0 1 1 1 0 AAA domain Mannitol_dh PF01232.23 CDJ61940.1 - 0.99 9.6 5.1 2.3 8.4 0.8 2.4 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Cyclin_C_2 PF16899.5 CDJ61940.1 - 3.1 8.2 5.5 6.5 7.2 1.1 2.8 2 1 0 2 2 2 0 Cyclin C-terminal domain RIFIN PF02009.16 CDJ61940.1 - 4.2 7.2 11.9 3.3 7.5 3.6 2.4 2 0 0 2 2 2 0 Rifin SR-25 PF10500.9 CDJ61941.1 - 0.00047 19.8 19.7 0.00047 19.8 19.7 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein LMBR1 PF04791.16 CDJ61941.1 - 0.95 8.3 9.1 1 8.2 9.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC2_membrane_3 PF12698.7 CDJ61941.1 - 1.5 7.8 7.5 2.2 7.3 7.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MALT1_Ig PF18703.1 CDJ61941.1 - 7.5 6.6 13.1 3.6 7.6 11.0 1.6 1 1 0 1 1 1 0 MALT1 Ig-like domain U3_assoc_6 PF08640.11 CDJ61942.1 - 7.5e-12 45.2 4.9 7.5e-12 45.2 4.9 2.8 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 SR-25 PF10500.9 CDJ61942.1 - 0.0018 17.9 2.4 0.0018 17.9 2.4 11.0 8 3 3 11 11 11 4 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CDJ61942.1 - 0.012 15.9 14.1 0.012 15.9 14.1 14.5 13 3 0 13 13 13 0 Domain of unknown function (DUF755) Pep_M12B_propep PF01562.19 CDJ61942.1 - 0.18 12.1 8.1 0.32 11.2 0.3 3.7 2 1 0 2 2 2 0 Reprolysin family propeptide CDC27 PF09507.10 CDJ61943.1 - 9e-05 22.0 18.0 0.00019 21.0 18.0 1.4 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF755 PF05501.11 CDJ61943.1 - 0.042 14.1 7.3 0.14 12.4 7.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Na_trans_assoc PF06512.13 CDJ61943.1 - 0.12 12.7 18.9 0.24 11.7 18.9 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Mpp10 PF04006.12 CDJ61943.1 - 0.19 10.2 24.5 0.29 9.5 24.5 1.4 1 0 0 1 1 1 0 Mpp10 protein MID_MedPIWI PF18296.1 CDJ61943.1 - 0.35 10.6 3.3 0.68 9.7 3.3 1.6 1 0 0 1 1 1 0 MID domain of medPIWI DUF2722 PF10846.8 CDJ61943.1 - 1.5 7.7 25.5 0.11 11.4 20.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 CDJ61943.1 - 2 6.6 37.0 3 6.0 37.0 1.2 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 CDJ61943.1 - 3.6 7.7 6.3 1.1 9.3 3.4 1.8 2 0 0 2 2 2 0 DDHD domain BUD22 PF09073.10 CDJ61943.1 - 4.7 6.4 36.7 0.61 9.4 32.8 1.5 2 0 0 2 2 2 0 BUD22 Glyco_hydro_35 PF01301.19 CDJ61945.1 - 2.7e-06 27.2 0.0 2.7e-06 27.2 0.0 4.3 5 0 0 5 5 5 1 Glycosyl hydrolases family 35 DUF2722 PF10846.8 CDJ61945.1 - 0.00038 19.5 10.9 0.00038 19.5 10.9 6.8 4 2 1 6 6 6 2 Protein of unknown function (DUF2722) Med15 PF09606.10 CDJ61945.1 - 0.0029 16.4 15.5 0.0029 16.4 15.5 5.5 4 1 0 5 5 5 2 ARC105 or Med15 subunit of Mediator complex non-fungal CAC1F_C PF16885.5 CDJ61945.1 - 0.28 10.8 49.1 1.3 8.7 11.7 4.5 4 0 0 4 4 4 0 Voltage-gated calcium channel subunit alpha, C-term DUF2207 PF09972.9 CDJ61945.1 - 7.8 5.1 14.5 11 4.6 0.0 4.1 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) DUF3458_C PF17432.2 CDJ61946.1 - 8.9e-99 330.9 4.4 1.6e-98 330.0 4.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 CDJ61946.1 - 1.5e-47 161.9 0.1 2.5e-47 161.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 CDJ61946.1 - 3e-24 85.3 0.0 6.9e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 CDJ61946.1 - 8.9e-14 52.1 0.0 1.9e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CDJ61946.1 - 0.049 13.2 0.2 0.15 11.6 0.1 1.8 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Peptidase_M61 PF05299.12 CDJ61946.1 - 0.079 13.4 0.2 0.3 11.5 0.2 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Serpin PF00079.20 CDJ61948.1 - 1.6e-67 228.4 0.0 2e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Vg_Tdu PF07545.14 CDJ61948.1 - 0.18 11.6 0.7 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Vestigial/Tondu family Cpn60_TCP1 PF00118.24 CDJ61949.1 - 1.7e-86 290.8 16.2 3.7e-86 289.7 16.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fis1_TPR_C PF14853.6 CDJ61950.1 - 6.4e-16 58.2 0.2 1.1e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CDJ61950.1 - 0.0002 20.9 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDJ61950.1 - 0.00076 19.4 0.3 0.0022 18.0 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDJ61950.1 - 0.032 14.9 0.5 0.032 14.9 0.5 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDJ61950.1 - 0.035 14.6 0.1 0.054 14.0 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDJ61950.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDJ61950.1 - 0.083 13.6 0.0 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 CDJ61952.1 - 2.6e-14 52.9 9.1 3.2e-13 49.3 4.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDJ61952.1 - 6.4e-14 51.7 6.6 4.8e-11 42.2 3.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CDJ61952.1 - 0.00023 20.6 0.2 0.00023 20.6 0.2 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YrhC PF14143.6 CDJ61952.1 - 0.28 11.3 2.5 0.65 10.1 1.1 2.2 2 0 0 2 2 2 0 YrhC-like protein ECF_trnsprt PF12822.7 CDJ61952.1 - 0.36 10.9 8.7 0.25 11.4 5.1 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Metallophos PF00149.28 CDJ61953.1 - 2.4e-31 109.9 0.0 2.9e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDJ61953.1 - 5.9e-22 77.8 0.2 1.1e-21 77.0 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2722 PF10846.8 CDJ61954.1 - 0.00019 20.5 0.8 0.00019 20.5 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Mito_carr PF00153.27 CDJ61954.1 - 0.0093 15.9 10.0 0.44 10.5 4.3 3.3 1 1 1 2 2 2 1 Mitochondrial carrier protein Spt20 PF12090.8 CDJ61954.1 - 0.024 14.2 10.7 0.031 13.9 10.7 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CDJ61954.1 - 0.095 12.7 8.3 0.11 12.5 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRC1 PF09444.10 CDJ61954.1 - 0.29 11.6 2.0 0.51 10.8 2.0 1.3 1 0 0 1 1 1 0 MRC1-like domain Protamine_P2 PF00841.19 CDJ61954.1 - 1.9 9.0 8.4 3.2 8.3 8.4 1.3 1 0 0 1 1 1 0 Sperm histone P2 SseC PF04888.12 CDJ61954.1 - 3.3 7.2 8.4 6.8 6.2 8.4 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DEAD PF00270.29 CDJ61955.1 - 1.8e-27 96.2 1.0 7.4e-27 94.2 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDJ61955.1 - 3.9e-18 65.8 0.1 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDJ61955.1 - 0.0011 19.2 0.2 0.16 12.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain TCP PF03634.13 CDJ61955.1 - 0.0033 18.0 0.6 0.0033 18.0 0.6 5.1 4 2 1 5 5 5 1 TCP family transcription factor Arteri_nucleo PF01481.16 CDJ61955.1 - 0.0091 16.3 0.7 0.0091 16.3 0.7 4.1 4 0 0 4 4 4 1 Arterivirus nucleocapsid protein CSG2 PF16965.5 CDJ61955.1 - 2.5 6.9 6.5 0.68 8.8 0.1 2.6 2 0 0 2 2 2 0 Ceramide synthase regulator TFIIA PF03153.13 CDJ61955.1 - 3.8 7.4 61.1 1.2 9.0 21.1 3.3 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit EF-hand_13 PF17958.1 CDJ61956.1 - 3.4e-11 42.8 0.0 7.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDJ61956.1 - 4.7e-06 26.9 3.2 0.1 13.1 0.8 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDJ61956.1 - 0.0038 17.0 0.2 4.8 7.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDJ61956.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF1768 PF08719.11 CDJ61958.1 - 9.4e-15 55.2 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FHA PF00498.26 CDJ61958.1 - 2.5e-10 40.5 0.1 7.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDJ61958.1 - 5.8e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Peptidase_M41 PF01434.18 CDJ61960.1 - 4.8e-47 160.3 0.2 3.5e-46 157.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CDJ61960.1 - 7.4e-31 107.3 0.0 2.8e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Presenilin PF01080.17 CDJ61960.1 - 2 7.1 7.7 12 4.5 7.7 1.9 1 1 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 CDJ61960.1 - 2 7.3 39.9 1.9 7.3 32.4 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 CDJ61960.1 - 6.9 7.3 15.7 37 4.9 11.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAP PF08373.10 CDJ61961.1 - 1.2e-06 28.5 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 RAP domain V_ATPase_I PF01496.19 CDJ61961.1 - 0.0021 16.1 6.9 0.003 15.6 6.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1192 PF06698.11 CDJ61961.1 - 0.018 15.1 2.8 0.033 14.3 1.2 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF1192) Kei1 PF08552.11 CDJ61961.1 - 0.063 13.2 6.2 0.02 14.8 2.7 2.1 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.17 CDJ61961.1 - 0.32 11.1 9.9 0.043 14.0 4.6 2.2 2 0 0 2 2 2 0 DDHD domain SLC12 PF03522.15 CDJ61961.1 - 1 8.3 16.2 1.6 7.7 16.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 CDJ61961.1 - 1.3 7.3 2.8 1.9 6.8 2.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Exonuc_VII_L PF02601.15 CDJ61961.1 - 1.7 8.2 20.2 3 7.4 20.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zip PF02535.22 CDJ61961.1 - 3.2 6.9 7.4 6.3 5.9 7.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FAM222A PF15258.6 CDJ61961.1 - 4.8 6.2 31.3 9 5.3 31.3 1.5 1 0 0 1 1 1 0 Protein family of FAM222A LMBR1 PF04791.16 CDJ61961.1 - 4.8 6.0 6.1 6.1 5.6 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.13 CDJ61961.1 - 4.9 6.9 13.0 11 5.7 13.0 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 CDJ61961.1 - 5.4 7.2 11.7 15 5.7 11.7 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CSG2 PF16965.5 CDJ61961.1 - 6.2 5.7 8.6 11 4.8 8.6 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator MAJIN PF15077.6 CDJ61961.1 - 6.2 6.5 10.1 11 5.8 10.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein ALMT PF11744.8 CDJ61961.1 - 6.5 5.5 12.7 11 4.8 12.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydin_ADK PF17213.3 CDJ61961.1 - 7.9 6.7 13.9 20 5.4 13.9 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Sin_N PF04801.13 CDJ61961.1 - 8 5.6 30.5 14 4.7 30.5 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Hid1 PF12722.7 CDJ61961.1 - 8.9 4.3 16.2 13 3.7 16.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 CDJ61961.1 - 9.5 5.1 21.0 16 4.3 21.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 CDJ61961.1 - 9.7 6.2 15.7 18 5.3 15.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 CDJ61963.1 - 0.0052 16.9 3.6 0.0052 16.9 3.6 5.9 5 1 0 5 5 5 2 Coiled-coil domain containing protein (DUF2052) CLN3 PF02487.17 CDJ61963.1 - 0.012 14.7 0.5 0.012 14.7 0.5 5.3 6 0 0 6 6 6 0 CLN3 protein PsaL PF02605.15 CDJ61963.1 - 0.1 12.3 0.9 0.36 10.5 0.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI SR-25 PF10500.9 CDJ61964.1 - 5.6e-06 26.1 31.1 5.6e-06 26.1 31.1 7.6 4 1 3 7 7 7 4 Nuclear RNA-splicing-associated protein zf-met PF12874.7 CDJ61964.1 - 0.00024 21.4 2.0 0.00061 20.1 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDJ61964.1 - 0.0062 16.8 0.5 0.0062 16.8 0.5 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CDJ61964.1 - 0.051 13.2 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2 PF00096.26 CDJ61964.1 - 0.058 13.9 0.7 0.16 12.5 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF5062 PF16691.5 CDJ61964.1 - 0.062 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) zf-C2H2_4 PF13894.6 CDJ61964.1 - 0.092 13.6 0.4 0.27 12.2 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 CDJ61964.1 - 0.27 11.4 2.1 0.73 10.0 2.1 1.7 1 0 0 1 1 1 0 DBF zinc finger Med15 PF09606.10 CDJ61964.1 - 0.42 9.2 57.7 0.36 9.5 3.9 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Patched PF02460.18 CDJ61965.1 - 3.7e-35 121.3 0.0 3.7e-34 117.9 0.0 2.1 2 0 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 CDJ61965.1 - 1.2e-26 93.4 3.8 2.1e-26 92.6 3.8 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation DUF1700 PF08006.11 CDJ61968.1 - 0.0055 16.3 0.3 0.0062 16.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) TcpE PF12648.7 CDJ61968.1 - 0.0064 17.0 0.5 0.0086 16.6 0.5 1.2 1 0 0 1 1 1 1 TcpE family EXS PF03124.14 CDJ61968.1 - 0.0065 15.8 0.2 0.0072 15.7 0.2 1.0 1 0 0 1 1 1 1 EXS family DUF92 PF01940.16 CDJ61968.1 - 0.043 13.2 3.2 0.057 12.8 3.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF3377 PF11857.8 CDJ61968.1 - 0.077 12.9 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) UPF0227 PF05728.12 CDJ61968.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SNARE_assoc PF09335.11 CDJ61968.1 - 0.27 11.7 6.6 0.24 11.9 4.1 1.9 1 1 1 2 2 2 0 SNARE associated Golgi protein DUF677 PF05055.12 CDJ61968.1 - 1.3 7.9 4.9 3.8 6.3 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF677) RskA PF10099.9 CDJ61970.1 - 3.6 7.8 67.0 0.044 14.1 17.4 3.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RRM_7 PF16367.5 CDJ61971.1 - 0.0049 17.0 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif zf_CCCH_4 PF18345.1 CDJ61971.1 - 0.0075 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Zinc finger domain Chorion_2 PF03964.15 CDJ61971.1 - 0.03 15.2 0.6 0.03 15.2 0.6 2.4 2 0 0 2 2 2 0 Chorion family 2 RRM_1 PF00076.22 CDJ61971.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CDJ61971.1 - 0.059 13.3 1.2 0.063 13.2 0.1 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SR-25 PF10500.9 CDJ61971.1 - 0.14 11.8 1.7 0.19 11.3 1.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LepB_GAP_N PF18172.1 CDJ61971.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain AAA_8 PF12780.7 CDJ61972.1 - 7.7e-85 284.3 0.0 1.5e-82 276.9 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CDJ61972.1 - 7.6e-59 198.3 0.1 6.5e-57 192.0 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 CDJ61972.1 - 1.2e-58 198.8 14.4 2.4e-57 194.6 16.8 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CDJ61972.1 - 2.9e-48 164.5 0.3 2.7e-47 161.4 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CDJ61972.1 - 4.6e-25 88.2 1.9 2e-24 86.1 1.9 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDJ61972.1 - 1.6e-24 86.0 0.0 3.9e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDJ61972.1 - 2.4e-17 63.2 0.1 2.4e-12 47.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) SKA2 PF16740.5 CDJ61972.1 - 0.004 16.9 1.8 0.004 16.9 1.8 2.9 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 Mg_chelatase PF01078.21 CDJ61972.1 - 0.011 15.1 0.0 0.64 9.4 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CDJ61972.1 - 0.06 13.3 0.5 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3467 PF11950.8 CDJ61972.1 - 0.073 13.3 0.2 0.66 10.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3467) Phage_GP20 PF06810.11 CDJ61972.1 - 0.11 12.3 19.5 0.98 9.2 9.6 2.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF573 PF04504.14 CDJ61972.1 - 0.13 13.0 0.5 0.85 10.3 0.3 2.5 2 0 0 2 2 1 0 Protein of unknown function, DUF573 Occludin_ELL PF07303.13 CDJ61972.1 - 0.64 10.8 5.2 9.2 7.1 0.3 3.4 2 0 0 2 2 2 0 Occludin homology domain DUF4446 PF14584.6 CDJ61972.1 - 0.85 9.6 8.4 0.059 13.3 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) CHASE3 PF05227.13 CDJ61972.1 - 1.4 8.9 19.8 0.28 11.1 11.8 2.9 3 0 0 3 3 2 0 CHASE3 domain DUF4407 PF14362.6 CDJ61972.1 - 1.5 8.1 22.2 3.2 7.0 13.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 CDJ61972.1 - 2.4 8.0 16.5 0.63 9.8 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Retrotrans_gag PF03732.17 CDJ61972.1 - 2.6 8.4 9.9 0.55 10.5 0.3 4.2 5 0 0 5 5 5 0 Retrotransposon gag protein DUF948 PF06103.11 CDJ61972.1 - 2.9 8.2 12.3 3.7 7.9 0.8 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.27 CDJ61972.1 - 4.2 7.9 5.3 1.5e+02 2.9 0.0 4.3 5 0 0 5 5 5 0 ABC transporter LUC7 PF03194.15 CDJ61972.1 - 5.4 6.6 19.6 0.33 10.6 2.9 2.5 2 0 0 2 2 2 0 LUC7 N_terminus NPV_P10 PF05531.12 CDJ61972.1 - 9.1 6.8 9.6 0.69 10.4 0.4 3.5 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CDJ61972.1 - 9.2 6.4 17.0 0.77 9.9 4.2 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DnaJ PF00226.31 CDJ61973.1 - 2.3e-24 85.3 2.2 7.2e-24 83.7 2.2 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CDJ61973.1 - 2.6e-20 72.8 13.9 8.2e-17 61.3 6.3 2.7 1 1 1 2 2 2 2 X-domain of DnaJ-containing Peptidase_S46 PF10459.9 CDJ61973.1 - 0.73 8.4 12.6 1.2 7.7 12.6 1.2 1 0 0 1 1 1 0 Peptidase S46 Spt20 PF12090.8 CDJ61973.1 - 3.3 7.3 19.1 0.2 11.2 12.4 2.1 2 0 0 2 2 2 0 Spt20 family MID_MedPIWI PF18296.1 CDJ61973.1 - 3.7 7.3 9.1 4.8 6.9 3.2 2.4 2 0 0 2 2 2 0 MID domain of medPIWI FmdE PF02663.14 CDJ61973.1 - 5.8 7.0 6.1 0.85 9.7 0.3 2.5 2 1 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon AP2 PF00847.20 CDJ61974.1 - 2.9e-05 24.2 2.3 0.0002 21.5 2.3 2.5 1 0 0 1 1 1 1 AP2 domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_maxima-EMW001/GCA_000499605.1_EMW001_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_maxima-EMW001/GCA_000499605.1_EMW001_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_maxima-EMW001/GCA_000499605.1_EMW001_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Eimeria_maxima-EMW001/GCA_000499605.1_EMW001_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 00:58:45 2019 # [ok]