# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase PF00069.20 EEA04697.1 - 1.8e-38 132.2 0.0 2.9e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04697.1 - 1.9e-17 63.1 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA04697.1 - 0.0013 18.5 0.1 0.0035 17.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA04697.1 - 0.098 11.7 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF676 PF05057.9 EEA04698.1 - 2.4e-42 144.7 0.0 4.4e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 EEA04698.1 - 1.1e-19 70.2 0.3 4.7e-19 68.2 0.2 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) PGAP1 PF07819.8 EEA04698.1 - 1.1e-05 25.1 0.0 0.00014 21.5 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA04698.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EEA04698.1 - 0.046 13.0 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Oxidored_nitro PF00148.14 EEA04698.1 - 0.068 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Abhydrolase_6 PF12697.2 EEA04698.1 - 0.24 11.2 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Takusan PF04822.8 EEA04699.1 - 0.023 14.4 3.4 0.059 13.1 2.4 1.6 1 0 0 1 1 1 0 Takusan HNH_5 PF14279.1 EEA04699.1 - 0.027 14.4 1.3 0.083 12.9 0.9 1.9 1 1 0 1 1 1 0 HNH endonuclease ArfGap PF01412.13 EEA04699.1 - 4.1 7.1 14.2 1.1 9.0 5.8 2.3 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf Scm3 PF10384.4 EEA04700.1 - 0.016 14.6 0.7 0.044 13.2 0.5 1.8 1 0 0 1 1 1 0 Centromere protein Scm3 DUF2762 PF10960.3 EEA04700.1 - 0.14 11.8 8.8 0.043 13.5 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF4110 PF13422.1 EEA04700.1 - 0.2 11.5 3.1 0.21 11.4 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) AdoHcyase PF05221.12 EEA04701.1 - 4.6e-117 389.7 0.2 5.9e-117 389.3 0.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EEA04701.1 - 2.2e-69 232.4 2.5 3.6e-69 231.7 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA04701.1 - 1.2e-06 27.8 0.2 3.6e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EEA04701.1 - 0.0047 16.3 0.2 0.0085 15.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 EEA04701.1 - 0.012 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 EEA04701.1 - 0.016 15.2 0.6 0.065 13.2 0.4 2.0 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EEA04701.1 - 0.079 13.2 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding WD40 PF00400.27 EEA04702.1 - 2.8e-06 26.9 3.5 0.58 10.1 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat UPF0020 PF01170.13 EEA04703.1 - 1.2e-14 54.3 0.0 6.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EEA04703.1 - 5.7e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EEA04703.1 - 4.8e-06 26.2 0.2 0.00033 20.2 0.0 2.5 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EEA04703.1 - 0.01 14.9 0.7 0.2 10.6 0.0 2.4 3 0 0 3 3 3 0 N-6 DNA Methylase DUF2361 PF10153.4 EEA04704.1 - 2.1e-08 34.3 11.3 2.1e-08 34.3 7.8 2.8 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) tRNA-synt_1d PF00750.14 EEA04705.1 - 6.7e-102 340.9 0.9 9e-102 340.4 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EEA04705.1 - 3e-25 88.4 0.1 6.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EEA04705.1 - 2.6e-13 50.2 0.1 9.3e-13 48.5 0.1 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EEA04705.1 - 0.00027 20.1 0.0 0.00082 18.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEA04705.1 - 0.00047 18.9 0.1 0.05 12.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DUF2067 PF09840.4 EEA04705.1 - 0.0073 15.8 0.8 0.053 13.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) DapB_N PF01113.15 EEA04705.1 - 0.027 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.20 EEA04706.1 - 4.2e-19 68.7 0.2 1.8e-18 66.6 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04706.1 - 1.6e-09 37.2 1.5 1.5e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA04706.1 - 0.00049 19.1 0.4 0.14 11.0 0.1 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEA04706.1 - 0.0085 15.1 0.1 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA04706.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S9 PF00326.16 EEA04708.1 - 8e-34 116.7 0.0 1.2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA04708.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA04708.1 - 1.8e-06 28.0 0.0 4.7e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA04708.1 - 3.8e-05 23.3 0.1 0.00036 20.1 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA04708.1 - 0.00043 19.8 0.0 0.64 9.4 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EEA04708.1 - 0.05 13.0 0.0 4 6.7 0.0 2.3 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 EEA04708.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EEA04708.1 - 0.095 11.1 0.0 4.5 5.6 0.0 2.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EEA04708.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Tannase PF07519.6 EEA04708.1 - 0.23 10.1 0.0 0.69 8.5 0.0 1.6 2 0 0 2 2 2 0 Tannase and feruloyl esterase Methyltransf_18 PF12847.2 EEA04712.1 - 2.2e-14 53.9 0.0 3.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA04712.1 - 2.7e-14 53.0 1.2 9.5e-14 51.2 0.8 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA04712.1 - 1.8e-05 25.1 0.1 3.9e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA04712.1 - 2e-05 25.0 0.0 4.6e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA04712.1 - 8.6e-05 21.9 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEA04712.1 - 8.9e-05 22.7 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA04712.1 - 0.00012 21.1 0.0 0.00022 20.3 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEA04712.1 - 0.00026 21.0 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EEA04712.1 - 0.00057 19.2 0.1 0.00068 19.0 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 EEA04712.1 - 0.0013 18.5 0.0 0.0021 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA04712.1 - 0.0019 17.3 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EEA04712.1 - 0.0033 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.11 EEA04712.1 - 0.0056 15.5 1.2 0.007 15.2 0.8 1.3 1 1 0 1 1 1 1 mRNA capping enzyme DUF633 PF04816.7 EEA04712.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF633) MetW PF07021.7 EEA04712.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 EEA04712.1 - 0.029 13.4 0.1 0.055 12.5 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_20 PF12147.3 EEA04712.1 - 0.032 13.1 0.2 0.049 12.5 0.1 1.4 1 1 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EEA04712.1 - 0.032 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB SUKH_6 PF14568.1 EEA04712.1 - 0.033 14.6 2.6 2.3 8.7 0.1 2.4 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall AdoMet_MTase PF07757.8 EEA04712.1 - 0.036 14.1 0.1 0.074 13.1 0.0 1.7 2 0 0 2 2 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_9 PF08003.6 EEA04712.1 - 0.041 12.5 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Frataxin_Cyay PF01491.11 EEA04713.1 - 5e-16 58.4 0.1 6.9e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1352 PF07086.7 EEA04714.1 - 8.5 5.9 14.3 0.36 10.4 3.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) Pex24p PF06398.6 EEA04715.1 - 0.019 13.7 7.3 0.031 13.0 5.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3611 PF12263.3 EEA04715.1 - 0.021 14.2 0.6 0.053 12.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) MBOAT PF03062.14 EEA04715.1 - 0.045 12.8 0.2 0.045 12.8 0.1 2.2 2 0 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family Reticulon PF02453.12 EEA04715.1 - 0.26 10.8 9.3 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Reticulon SNF2_N PF00176.18 EEA04716.1 - 9.1e-57 192.1 1.7 9.4e-57 192.0 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA04716.1 - 7.4e-12 44.9 0.0 2.3e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Codanin-1_C PF15296.1 EEA04716.1 - 0.0081 16.0 0.2 0.084 12.7 0.0 2.5 2 0 0 2 2 2 1 Codanin-1 C-terminus PIG-S PF10510.4 EEA04718.1 - 2.1e-08 33.2 1.3 4.3e-08 32.2 0.9 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein GBP PF02263.14 EEA04718.1 - 0.0032 16.5 1.1 0.0046 16.0 0.1 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain ATP11 PF06644.6 EEA04719.1 - 1.5e-24 86.9 0.6 1.8e-24 86.6 0.4 1.0 1 0 0 1 1 1 1 ATP11 protein DUF4017 PF13209.1 EEA04719.1 - 0.0036 17.0 0.1 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4017) Sigma70_r1_2 PF00140.15 EEA04719.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 WD40 PF00400.27 EEA04720.1 - 1.3e-10 40.6 0.8 0.2 11.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Tim44 PF04280.10 EEA04722.1 - 0.044 13.7 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Tim44-like domain Herpes_UL24 PF01646.11 EEA04722.1 - 0.091 12.2 0.0 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Herpes virus protein UL24 Med30 PF11315.3 EEA04723.1 - 0.011 15.9 2.4 0.011 15.9 1.7 2.9 2 1 1 3 3 3 0 Mediator complex subunit 30 DUF1899 PF08953.6 EEA04723.1 - 2.2 7.9 4.2 1.9 8.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) DUF3522 PF12036.3 EEA04724.1 - 9.4e-15 54.8 13.2 2.1e-14 53.7 9.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF2935 PF11155.3 EEA04724.1 - 0.019 15.0 0.5 0.019 15.0 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3844 PF12955.2 EEA04724.1 - 0.76 9.9 5.1 5.9 7.0 3.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) HAD_2 PF13419.1 EEA04725.1 - 0.0069 16.6 0.3 0.032 14.4 0.2 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA04725.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EEA04726.1 - 3.4e-46 156.9 0.6 4.4e-46 156.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Sec1 PF00995.18 EEA04729.1 - 2e-127 426.2 22.3 2.3e-127 426.0 15.5 1.0 1 0 0 1 1 1 1 Sec1 family Sld5 PF05916.6 EEA04731.1 - 0.072 13.3 0.3 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 GINS complex protein PP2C PF00481.16 EEA04732.1 - 1e-45 156.1 0.0 1.9e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA04732.1 - 1.6e-05 24.6 0.0 9.6e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEA04732.1 - 0.00084 18.8 0.0 0.0089 15.4 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4582 PF15189.1 EEA04732.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Iron_traffic PF04362.9 EEA04732.1 - 0.15 11.5 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking DUF2729 PF10870.3 EEA04732.1 - 2.3 7.9 9.8 5.6 6.7 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) DUF4658 PF15555.1 EEA04734.1 - 6 6.7 0.0 12 5.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) ABC_tran PF00005.22 EEA04737.1 - 7.5e-19 68.3 0.0 3.9e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.18 EEA04737.1 - 0.0019 18.1 0.7 0.0058 16.5 0.5 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EEA04737.1 - 0.039 13.4 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EEA04737.1 - 0.088 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EEA04737.1 - 0.23 10.1 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SMC_N PF02463.14 EEA04737.1 - 0.4 9.8 3.3 1.6 7.8 0.5 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Peptidase_C1 PF00112.18 EEA04738.1 - 6.8e-37 127.4 5.3 1e-36 126.8 3.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EEA04738.1 - 0.0019 16.7 0.2 0.004 15.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase C1-like family AMP-binding PF00501.23 EEA04742.1 - 1.9e-69 234.0 0.0 2.6e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TFIIH_BTF_p62_N PF08567.6 EEA04742.1 - 0.069 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Jacalin PF01419.12 EEA04745.1 - 0.015 15.1 11.8 0.025 14.4 0.4 5.4 5 2 0 6 6 6 0 Jacalin-like lectin domain PH_3 PF14593.1 EEA04745.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF900 PF05990.7 EEA04746.1 - 1.6e-25 89.7 0.0 4.5e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) SPC12 PF06645.8 EEA04750.1 - 1.1 9.1 6.9 0.46 10.3 0.3 3.2 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_2 PF13347.1 EEA04751.1 - 0.028 12.8 16.0 0.061 11.7 11.1 1.5 1 0 0 1 1 1 0 MFS/sugar transport protein MFS_1 PF07690.11 EEA04752.1 - 1.3e-05 24.0 36.7 2.3e-05 23.2 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-DNL PF05180.7 EEA04754.1 - 0.03 14.0 2.2 3.1 7.6 0.1 2.6 2 0 0 2 2 2 0 DNL zinc finger PAN_4 PF14295.1 EEA04755.1 - 1.8e-05 24.3 1.0 1.8e-05 24.3 0.7 3.2 3 0 0 3 3 3 1 PAN domain PAN_1 PF00024.21 EEA04755.1 - 3.2e-05 23.6 0.6 3.2e-05 23.6 0.4 3.1 3 0 0 3 3 3 1 PAN domain PAN_3 PF08277.7 EEA04755.1 - 0.019 14.6 11.6 0.15 11.6 0.9 2.8 2 0 0 2 2 2 0 PAN-like domain CarbpepA_inh PF02977.10 EEA04755.1 - 0.26 10.8 7.5 0.87 9.2 0.5 2.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor PAN_2 PF08276.6 EEA04755.1 - 1.6 8.6 7.0 0.71 9.7 0.6 3.2 2 1 1 3 3 3 0 PAN-like domain TPT PF03151.11 EEA04756.1 - 2.4e-12 46.7 9.0 2.4e-12 46.7 6.2 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEA04756.1 - 1.7e-08 33.7 22.3 2.5e-08 33.2 15.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEA04756.1 - 0.00065 19.7 6.5 0.00065 19.7 4.5 3.2 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 EEA04757.1 - 1.7e-09 37.4 18.8 5.1e-08 32.7 6.4 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EEA04757.1 - 0.0023 18.0 16.0 0.11 12.7 1.1 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EEA04757.1 - 0.0052 16.8 7.7 0.0052 16.8 5.3 3.1 3 1 1 4 4 4 2 EamA-like transporter family UAA PF08449.6 EEA04757.1 - 0.0089 14.9 23.5 0.29 10.0 16.8 2.7 1 1 0 1 1 1 1 UAA transporter family UPF0546 PF10639.4 EEA04757.1 - 0.18 11.6 6.6 0.05 13.4 1.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EEA04758.1 - 2.3e-13 50.0 8.9 2.3e-13 50.0 6.1 3.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEA04758.1 - 1.2e-06 27.7 26.8 2.7e-06 26.5 18.5 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEA04758.1 - 0.003 17.5 11.9 0.003 17.5 8.2 3.4 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EEA04758.1 - 0.0036 17.4 5.1 0.0036 17.4 3.5 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF996 PF06195.8 EEA04759.1 - 0.00014 21.8 3.2 0.057 13.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF996) TMEM95 PF15203.1 EEA04759.1 - 0.021 14.2 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 TMEM95 family DUF485 PF04341.7 EEA04759.1 - 0.2 11.4 1.5 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Aa_trans PF01490.13 EEA04761.1 - 2.2e-15 56.0 48.1 3.1e-13 48.9 20.0 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein NB PF04159.8 EEA04761.1 - 5.5 6.7 10.7 0.37 10.5 0.8 3.2 3 0 0 3 3 3 0 NB glycoprotein GSHPx PF00255.14 EEA04762.1 - 8.3e-25 86.2 0.1 1.4e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EEA04762.1 - 4e-05 23.2 0.0 6.6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEA04762.1 - 0.0079 15.7 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Redoxin LisH PF08513.6 EEA04763.1 - 1e-05 25.0 0.2 2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.5 EEA04763.1 - 0.00053 19.9 0.7 0.0027 17.6 0.4 2.1 1 1 0 1 1 1 1 FOP N terminal dimerisation domain mRNA_triPase PF02940.10 EEA04764.1 - 8.1e-23 81.2 0.5 1.2e-22 80.6 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SAB PF04382.8 EEA04764.1 - 0.068 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 SAB domain MSP1_C PF07462.6 EEA04765.1 - 0.012 14.0 9.1 0.018 13.4 6.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SRCR_2 PF15494.1 EEA04765.1 - 9.2 6.5 8.6 31 4.8 0.1 4.0 4 0 0 4 4 4 0 Scavenger receptor cysteine-rich domain Chorein_N PF12624.2 EEA04766.1 - 1.8e-22 79.0 5.8 2.4e-22 78.6 0.7 3.6 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEA04766.1 - 1e-05 25.5 0.2 4.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain ABC_membrane PF00664.18 EEA04768.1 - 4.8e-24 85.2 35.3 2.9e-16 59.7 12.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EEA04768.1 - 1.3e-23 83.8 0.0 9.8e-13 48.5 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.1 EEA04768.1 - 8.5e-09 34.8 1.1 0.0024 17.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA04768.1 - 2.1e-06 27.6 0.3 0.0016 18.3 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EEA04768.1 - 1.1e-05 24.5 0.1 0.018 13.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 EEA04768.1 - 1.4e-05 25.5 0.0 0.13 12.7 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EEA04768.1 - 0.00018 21.0 0.1 0.33 10.3 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 EEA04768.1 - 0.00036 21.3 0.9 0.11 13.3 0.0 3.7 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EEA04768.1 - 0.00037 19.7 0.1 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EEA04768.1 - 0.00037 20.2 0.0 0.84 9.3 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_25 PF13481.1 EEA04768.1 - 0.0004 19.8 0.0 0.21 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEA04768.1 - 0.00054 19.2 0.7 0.69 9.0 0.1 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EEA04768.1 - 0.00056 20.2 5.2 1.5 9.1 0.0 4.2 4 0 0 4 4 3 1 AAA domain NACHT PF05729.7 EEA04768.1 - 0.00095 18.8 0.6 0.57 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain cobW PF02492.14 EEA04768.1 - 0.0014 18.0 1.2 1.2 8.6 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EEA04768.1 - 0.0016 18.4 0.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 EEA04768.1 - 0.0039 16.9 0.2 2.4 7.8 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA04768.1 - 0.0045 17.1 1.2 2.2 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA04768.1 - 0.0084 15.6 1.5 0.46 9.9 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EEA04768.1 - 0.015 15.6 0.0 0.015 15.6 0.0 4.6 4 1 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 EEA04768.1 - 0.018 15.2 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 EEA04768.1 - 0.057 12.1 0.2 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 EEA04768.1 - 0.059 12.7 0.1 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EEA04768.1 - 0.12 12.1 0.1 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EEA04768.1 - 0.14 12.0 0.6 16 5.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEA04768.1 - 0.16 11.0 0.1 7.5 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EEA04768.1 - 0.19 11.5 6.7 0.083 12.6 0.1 3.1 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.1 EEA04768.1 - 0.23 11.0 0.0 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EEA04768.1 - 0.51 10.1 9.1 0.28 10.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 Turandot PF07240.6 EEA04769.1 - 0.097 12.1 0.3 5.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot DEAD PF00270.24 EEA04770.1 - 5.9e-19 68.1 0.0 1.7e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA04770.1 - 4.4e-16 58.5 0.0 1.6e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA04770.1 - 5.2e-06 26.4 0.0 2.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CAF1 PF04857.15 EEA04773.1 - 2.1e-59 200.9 3.0 3.1e-59 200.4 2.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_T PF00929.19 EEA04773.1 - 0.039 14.2 0.0 0.094 12.9 0.0 1.6 2 0 0 2 2 2 0 Exonuclease adh_short PF00106.20 EEA04775.1 - 6e-19 68.5 0.0 1.8e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EEA04775.1 - 1.5e-06 27.8 0.0 3.1e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EEA04775.1 - 4.9e-06 26.3 0.0 4.6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EEA04775.1 - 0.00027 19.7 0.2 0.00045 19.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEA04775.1 - 0.0013 17.6 0.2 0.0043 15.9 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EEA04775.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Wax2_C PF12076.3 EEA04775.1 - 0.13 12.0 0.0 11 5.7 0.0 2.9 2 1 0 3 3 3 0 WAX2 C-terminal domain NMT PF01233.14 EEA04776.1 - 4.4e-59 198.7 0.1 1.1e-58 197.4 0.1 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EEA04776.1 - 1.4e-52 177.8 5.5 2.8e-41 140.9 1.6 3.4 2 1 0 3 3 3 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EEA04776.1 - 0.00059 19.7 0.0 0.0084 15.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA04776.1 - 0.0028 17.7 0.1 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA04776.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RCC1 PF00415.13 EEA04777.1 - 5.1e-102 333.9 58.4 7.7e-14 51.6 0.2 14.9 15 1 0 15 15 15 12 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA04777.1 - 3.9e-47 156.9 80.3 6.2e-08 32.0 0.8 13.8 13 0 0 13 13 13 12 Regulator of chromosome condensation (RCC1) repeat Hint PF01079.15 EEA04777.1 - 0.19 10.8 0.3 0.33 10.1 0.2 1.3 1 0 0 1 1 1 0 Hint module NTF2 PF02136.15 EEA04778.1 - 1.6e-09 38.1 0.0 5.6e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain NUDIX PF00293.23 EEA04779.1 - 1e-16 60.7 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DSHCT PF08148.7 EEA04782.1 - 8.2e-42 142.4 0.0 1.7e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEA04782.1 - 4.2e-22 78.4 0.1 6.8e-21 74.4 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Pkinase PF00069.20 EEA04784.1 - 6.2e-64 215.6 0.0 2.4e-33 115.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04784.1 - 4.7e-28 97.9 0.0 5.6e-18 64.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_6 PF13405.1 EEA04784.1 - 2.9e-11 42.2 0.4 0.032 14.1 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EEA04784.1 - 1e-07 30.7 5.0 0.0012 18.0 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 EEA04784.1 - 1.8e-05 23.8 2.5 0.0017 17.5 0.1 3.9 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 EEA04784.1 - 0.00017 21.6 5.8 0.1 12.7 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA04784.1 - 0.12 12.0 7.0 16 5.2 0.3 5.0 4 1 1 5 5 5 0 EF-hand domain pair Kdo PF06293.9 EEA04784.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.23 EEA04785.1 - 1.2e-37 129.2 0.3 2.1e-37 128.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_5 PF13854.1 EEA04785.1 - 3.9e-28 96.8 2.2 4.3e-06 26.5 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EEA04785.1 - 2.5e-25 88.0 13.4 7.9e-10 38.3 0.2 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EEA04785.1 - 2.3e-24 84.9 12.7 6.3e-07 29.3 0.0 7.2 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EEA04785.1 - 9.5e-18 63.1 2.2 0.00063 19.4 0.0 5.9 4 1 1 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EEA04785.1 - 6.3e-14 51.4 10.4 0.0092 16.1 0.0 6.4 3 2 4 7 7 7 4 Kelch motif Kelch_1 PF01344.20 EEA04785.1 - 1.2e-11 43.9 0.6 0.00083 18.8 0.0 5.2 6 0 0 6 6 6 2 Kelch motif RAG2 PF03089.9 EEA04785.1 - 6.7e-06 25.0 0.1 0.041 12.6 0.0 2.6 3 0 0 3 3 3 2 Recombination activating protein 2 Syja_N PF02383.13 EEA04786.1 - 0.036 12.8 1.1 0.24 10.1 0.1 2.0 2 0 0 2 2 2 0 SacI homology domain DUF2465 PF10239.4 EEA04786.1 - 0.098 11.8 1.2 0.38 9.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) PPP4R2 PF09184.6 EEA04787.1 - 0.0004 20.0 1.3 0.0004 20.0 0.9 2.0 1 1 0 1 1 1 1 PPP4R2 ORC5_C PF14630.1 EEA04787.1 - 0.043 13.2 0.4 0.068 12.6 0.3 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus eIF3_p135 PF12807.2 EEA04788.1 - 6.4e-10 39.2 0.0 3.6e-09 36.8 0.0 2.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EEA04788.1 - 0.00076 19.3 1.1 0.47 10.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA04788.1 - 0.005 16.6 0.2 1.2 9.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat CTNNB1_binding PF08347.6 EEA04789.1 - 0.053 13.7 9.2 0.048 13.8 5.9 1.3 1 1 0 1 1 1 0 N-terminal CTNNB1 binding Hydantoinase_A PF01968.13 EEA04790.1 - 0.055 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase zf-CCCH PF00642.19 EEA04791.1 - 3.6e-07 29.6 0.5 7.7e-07 28.6 0.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 EEA04791.1 - 2.2e-05 24.1 0.1 0.42 10.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat EGF_CA PF07645.10 EEA04792.1 - 8.5e-05 22.4 23.2 0.00011 22.1 3.9 2.4 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.2 EEA04792.1 - 0.00042 20.2 8.8 0.00042 20.2 6.1 2.4 2 0 0 2 2 2 1 EGF domain EGF PF00008.22 EEA04792.1 - 1.7 8.7 16.3 0.077 12.9 3.5 2.5 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 EEA04792.1 - 2.1 8.5 5.6 0.22 11.6 0.5 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.2 EEA04792.1 - 6 6.6 12.0 0.044 13.4 2.4 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like Sec20 PF03908.8 EEA04793.1 - 9.8e-05 21.9 2.8 9.8e-05 21.9 1.9 2.5 2 1 0 2 2 2 1 Sec20 DUF4200 PF13863.1 EEA04793.1 - 0.022 14.6 3.3 0.022 14.6 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V-SNARE_C PF12352.3 EEA04793.1 - 0.03 14.3 4.3 0.27 11.3 0.7 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Guanylin PF02058.10 EEA04793.1 - 0.13 12.3 0.1 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Guanylin precursor Occludin_ELL PF07303.8 EEA04793.1 - 0.19 12.4 6.1 0.37 11.5 3.8 1.8 1 1 0 1 1 1 0 Occludin homology domain DUF342 PF03961.8 EEA04793.1 - 1.2 7.5 8.9 1.4 7.2 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Synaptobrevin PF00957.16 EEA04793.1 - 2.5 7.7 11.5 2.6 7.6 0.5 2.9 3 0 0 3 3 3 0 Synaptobrevin Syntaxin-6_N PF09177.6 EEA04793.1 - 4.1 7.8 9.2 3.5 8.0 2.4 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF947 PF06102.7 EEA04794.1 - 2e-29 102.5 23.6 2.5e-29 102.2 16.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF3378 PF11858.3 EEA04794.1 - 0.73 9.9 4.6 4.1 7.5 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3378) Spore_III_AB PF09548.5 EEA04794.1 - 3.6 7.3 7.7 14 5.3 5.1 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3779 PF12621.3 EEA04796.1 - 0.082 12.7 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Phosphate metabolism protein HEAT_EZ PF13513.1 EEA04797.1 - 0.00085 19.7 0.0 0.005 17.2 0.0 2.4 1 1 1 2 2 2 1 HEAT-like repeat HEAT PF02985.17 EEA04797.1 - 0.0059 16.5 0.3 3.8 7.8 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat MMR_HSR1 PF01926.18 EEA04798.1 - 6.2e-17 61.6 0.1 1.1e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EEA04798.1 - 1.4e-14 53.6 0.1 2.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EEA04798.1 - 2e-11 43.3 0.0 5.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEA04798.1 - 1.9e-05 25.1 0.0 7.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEA04798.1 - 3.1e-05 23.8 0.2 0.00039 20.2 0.1 2.3 1 1 0 1 1 1 1 Dynamin family Arf PF00025.16 EEA04798.1 - 0.04 13.1 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.11 EEA04798.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Spindle_Spc25 PF08234.7 EEA04799.1 - 3.6e-18 65.3 1.2 3.6e-18 65.3 0.8 2.3 3 1 0 3 3 3 1 Chromosome segregation protein Spc25 ERM PF00769.14 EEA04799.1 - 0.0023 17.4 5.1 0.0038 16.8 3.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HAUS4 PF14735.1 EEA04799.1 - 0.015 14.5 5.3 0.028 13.7 3.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Allexi_40kDa PF05549.6 EEA04799.1 - 0.022 14.0 2.8 0.039 13.2 1.9 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Muted PF14942.1 EEA04799.1 - 0.026 14.3 7.3 0.056 13.3 5.1 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein OmpH PF03938.9 EEA04799.1 - 0.044 13.7 3.2 0.11 12.4 2.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spectrin PF00435.16 EEA04799.1 - 0.15 12.3 4.3 0.49 10.7 3.0 1.9 2 1 0 2 2 2 0 Spectrin repeat Enkurin PF13864.1 EEA04799.1 - 0.15 12.2 5.2 0.4 10.9 3.6 1.8 1 0 0 1 1 1 0 Calmodulin-binding DUF4413 PF14372.1 EEA04799.1 - 0.92 9.5 5.9 26 4.8 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) DASH_Spc34 PF08657.5 EEA04799.1 - 4 7.0 11.8 0.74 9.4 3.9 2.3 1 1 0 2 2 2 0 DASH complex subunit Spc34 Fib_alpha PF08702.5 EEA04799.1 - 5.5 7.1 9.2 4.2 7.4 5.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EEA04799.1 - 6.8 6.2 8.4 17 4.9 5.8 1.8 1 1 0 1 1 1 0 IncA protein Asn_synthase PF00733.16 EEA04800.1 - 3.3e-19 69.3 0.0 1.4e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Asparagine synthase Lipase PF00151.14 EEA04801.1 - 2.5 7.2 6.7 0.22 10.6 0.2 2.3 3 0 0 3 3 3 0 Lipase TK PF00265.13 EEA04803.1 - 3.4e-56 189.5 1.9 3.9e-56 189.3 1.3 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.1 EEA04803.1 - 0.0021 18.2 0.1 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA04803.1 - 0.0037 17.1 0.2 0.0061 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEA04803.1 - 0.22 11.1 2.5 2.4 7.7 1.7 2.0 1 1 0 1 1 1 0 Archaeal ATPase TSP_1 PF00090.14 EEA04805.1 - 1.4e-22 79.5 37.4 2.6e-10 40.2 3.8 3.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.22 EEA04805.1 - 1.4e-05 24.8 5.2 1.4e-05 24.8 3.6 3.2 3 0 0 3 3 3 1 EGF-like domain Chorein_N PF12624.2 EEA04806.1 - 2.1e-32 111.1 4.0 5.3e-32 109.8 0.3 3.3 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEA04806.1 - 0.0036 17.4 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Cullin_Nedd8 PF10557.4 EEA04807.1 - 5e-07 29.4 1.0 1.5e-06 27.9 0.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Acetyltransf_1 PF00583.19 EEA04808.1 - 1.8e-11 43.8 0.0 3.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA04808.1 - 0.00042 20.4 0.5 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA04808.1 - 0.00084 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA04808.1 - 0.0019 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEA04808.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E_raikovi_mat PF06360.6 EEA04808.1 - 0.051 13.7 0.7 0.12 12.5 0.3 1.8 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone COesterase PF00135.23 EEA04810.1 - 1.3e-63 215.5 0.1 1.5e-62 212.0 0.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA04810.1 - 3.2e-10 39.9 0.2 1.5e-09 37.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA04810.1 - 2.1e-06 27.5 0.0 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA04810.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EEA04810.1 - 0.0031 16.4 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 EEA04810.1 - 0.041 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EEA04810.1 - 0.043 13.0 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EEA04810.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Nse4_C PF08743.5 EEA04811.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 Nse4 C-terminal DCX PF03607.12 EEA04812.1 - 4.3e-08 32.6 0.0 9.5e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Doublecortin p25-alpha PF05517.7 EEA04812.1 - 2.4e-06 27.8 0.2 4.4e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 p25-alpha Ribosomal_S7e PF01251.13 EEA04813.1 - 2.2e-66 222.9 0.1 2.4e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Plus-3 PF03126.13 EEA04815.1 - 1.2e-13 51.0 0.3 1.1e-12 47.9 0.0 2.6 2 0 0 2 2 2 1 Plus-3 domain Daxx PF03344.10 EEA04815.1 - 3.3 6.0 53.5 0.0087 14.6 30.0 1.8 2 0 0 2 2 2 0 Daxx Family CS PF04969.11 EEA04816.1 - 1.6e-10 41.3 3.6 6e-10 39.5 2.5 1.8 1 1 0 1 1 1 1 CS domain DUF2096 PF09869.4 EEA04816.1 - 0.024 14.5 0.5 0.031 14.1 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) PUF PF00806.14 EEA04817.1 - 7.9e-09 34.5 9.1 0.011 15.1 0.0 6.1 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Sec63 PF02889.11 EEA04818.1 - 4.6e-116 387.4 10.5 1.3e-74 251.2 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEA04818.1 - 2.2e-31 108.6 0.1 4.4e-25 88.1 0.1 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EEA04818.1 - 2.2e-07 30.8 0.0 1.5e-06 28.2 0.0 2.4 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA04818.1 - 3e-07 30.2 0.0 1.3e-05 24.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DnaJ PF00226.26 EEA04819.1 - 1.3e-24 85.7 0.2 5.1e-24 83.7 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EEA04819.1 - 4.6e-09 36.1 2.9 4.6e-09 36.1 2.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA04819.1 - 9.2e-09 35.1 3.1 9.2e-09 35.1 2.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEA04819.1 - 5.6e-07 29.5 15.3 0.0025 17.9 0.9 3.5 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EEA04819.1 - 0.0006 19.9 4.4 0.31 11.4 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA04819.1 - 0.0072 16.6 7.9 0.82 10.1 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-DBF PF07535.7 EEA04819.1 - 0.072 12.7 2.2 0.18 11.4 0.2 2.5 2 0 0 2 2 2 0 DBF zinc finger zf-UBP PF02148.14 EEA04819.1 - 0.1 12.7 1.6 0.31 11.1 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_6 PF13912.1 EEA04819.1 - 7.5 6.6 13.4 0.54 10.2 0.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger FHA PF00498.21 EEA04820.1 - 4.2e-16 58.8 0.9 4.2e-16 58.8 0.6 2.1 2 1 1 3 3 3 1 FHA domain FBA PF04300.8 EEA04820.1 - 0.046 13.6 0.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 F-box associated region SNF2_N PF00176.18 EEA04822.1 - 2e-50 171.2 0.4 6.8e-50 169.5 0.3 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA04822.1 - 3.4e-15 55.6 0.0 6.3e-14 51.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA04822.1 - 3.1e-09 36.9 1.9 1.4e-08 34.7 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA04822.1 - 3.4e-06 26.6 0.0 0.028 13.9 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA04822.1 - 0.057 13.5 0.0 0.22 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain Alpha-amylase PF00128.19 EEA04823.1 - 1.8e-60 204.9 0.1 1.4e-57 195.4 0.1 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EEA04823.1 - 3.7e-09 36.6 0.3 0.0015 18.6 0.0 3.0 3 0 0 3 3 3 2 Alpha amylase, C-terminal all-beta domain PP2C PF00481.16 EEA04824.1 - 7.8e-11 41.8 0.0 9.6e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEA04824.1 - 1.9e-06 27.4 0.0 1.4e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA04824.1 - 4.7e-06 26.4 0.0 0.00051 19.7 0.0 2.5 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Acyl-CoA_dh_M PF02770.14 EEA04824.1 - 0.02 14.3 0.0 4.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, middle domain Clp1 PF06807.9 EEA04826.1 - 6.2e-12 45.6 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEA04826.1 - 8.7e-11 41.6 0.0 1.2e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEA04826.1 - 4.2e-05 24.3 0.0 0.0003 21.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA04826.1 - 0.00074 19.8 0.0 0.0038 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EEA04826.1 - 0.0019 17.6 0.0 0.0037 16.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EEA04826.1 - 0.0046 16.9 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EEA04826.1 - 0.0046 16.5 0.2 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EEA04826.1 - 0.0067 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA04826.1 - 0.0076 16.2 0.1 0.038 13.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EEA04826.1 - 0.012 15.7 0.3 0.43 10.7 0.0 3.0 2 1 1 3 3 3 0 RNA helicase ABC_tran PF00005.22 EEA04826.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EEA04826.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_31 PF13614.1 EEA04826.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA04826.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EEA04826.1 - 0.082 12.0 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.20 EEA04826.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 EEA04826.1 - 0.14 11.7 0.0 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 EEA04826.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase zf-CCCH PF00642.19 EEA04827.1 - 1.9 8.2 23.9 0.66 9.7 0.6 5.0 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3610 PF12272.3 EEA04828.1 - 0.00015 21.4 0.4 0.00091 18.9 0.3 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3610) Tropomyosin PF00261.15 EEA04828.1 - 0.018 14.1 18.5 0.28 10.2 1.9 2.7 2 0 0 2 2 2 0 Tropomyosin Sec16 PF12932.2 EEA04828.1 - 0.14 12.0 1.8 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region APG6 PF04111.7 EEA04828.1 - 0.59 9.1 26.7 0.027 13.5 0.3 4.0 4 0 0 4 4 4 0 Autophagy protein Apg6 SlyX PF04102.7 EEA04828.1 - 7.2 7.0 18.3 0.63 10.4 1.0 4.6 4 1 0 4 4 4 0 SlyX Tbf5 PF06331.7 EEA04828.1 - 8 6.3 13.6 0.23 11.2 0.9 4.1 3 1 0 4 4 4 0 Transcription factor TFIIH complex subunit Tfb5 DHH PF01368.15 EEA04830.1 - 9.5e-11 41.5 2.0 3.6e-10 39.6 0.8 2.2 2 1 0 2 2 2 1 DHH family Chorein_N PF12624.2 EEA04831.1 - 5.7e-23 80.7 0.1 2.4e-22 78.6 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Peptidase_C48 PF02902.14 EEA04833.1 - 8.5e-39 133.4 4.1 1.6e-38 132.4 2.8 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cofilin_ADF PF00241.15 EEA04834.1 - 1.6e-27 95.8 0.1 1.8e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA PF00004.24 EEA04835.1 - 3.6e-39 133.9 0.0 8.3e-39 132.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA04835.1 - 8.3e-08 31.5 0.0 1.8e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEA04835.1 - 3.2e-06 27.1 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEA04835.1 - 6.7e-05 23.0 0.5 0.0009 19.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA04835.1 - 8.4e-05 22.0 0.2 0.0053 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EEA04835.1 - 0.00022 20.9 0.6 0.0039 16.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA04835.1 - 0.00039 21.2 0.0 0.0015 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EEA04835.1 - 0.00077 19.1 0.7 0.0064 16.1 0.0 2.5 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 EEA04835.1 - 0.0017 18.2 0.2 0.011 15.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA04835.1 - 0.0022 18.2 0.2 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEA04835.1 - 0.0029 16.8 0.1 0.0062 15.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEA04835.1 - 0.0033 17.0 0.2 0.027 14.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA04835.1 - 0.0045 15.7 0.1 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EEA04835.1 - 0.0084 15.8 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEA04835.1 - 0.011 15.1 0.2 0.032 13.6 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EEA04835.1 - 0.012 15.6 0.0 0.048 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Parvo_NS1 PF01057.12 EEA04835.1 - 0.016 14.1 0.2 0.24 10.2 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EEA04835.1 - 0.017 14.9 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEA04835.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EEA04835.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase SKI PF01202.17 EEA04835.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.10 EEA04835.1 - 0.067 12.9 1.9 2.2 7.9 0.0 3.4 3 2 1 4 4 3 0 NTPase AAA_10 PF12846.2 EEA04835.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 EEA04835.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 EEA04835.1 - 0.13 11.7 0.2 1.1 8.6 0.1 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 EEA04835.1 - 0.22 11.8 1.4 0.86 9.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter S10_plectin PF03501.10 EEA04836.1 - 1.8e-39 133.5 0.2 2.1e-39 133.2 0.2 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Arf PF00025.16 EEA04837.1 - 2.9e-15 55.9 0.0 5.4e-15 55.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA04837.1 - 4.6e-08 32.4 0.2 7.6e-08 31.7 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EEA04837.1 - 2.8e-05 24.5 0.0 7.2e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EEA04837.1 - 8.3e-05 21.8 0.1 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEA04837.1 - 9e-05 21.9 0.2 0.00016 21.0 0.0 1.5 2 0 0 2 2 2 1 Ras family AAA_14 PF13173.1 EEA04837.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA04837.1 - 0.0023 16.8 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EEA04837.1 - 0.0073 15.8 0.3 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEA04837.1 - 0.027 14.4 0.2 0.046 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EEA04837.1 - 0.031 14.6 6.9 0.28 11.5 4.8 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EEA04837.1 - 0.052 13.5 0.1 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EEA04837.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEA04837.1 - 0.073 12.5 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEA04837.1 - 0.08 13.7 0.3 0.3 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA04837.1 - 0.14 12.0 0.3 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA04837.1 - 0.37 11.0 1.7 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 ABC transporter Pox_A3L PF05288.6 EEA04838.1 - 0.066 12.9 0.5 0.17 11.6 0.1 1.9 1 1 0 1 1 1 0 Poxvirus A3L Protein ApoO PF09769.4 EEA04838.1 - 0.15 11.7 1.1 0.47 10.1 0.7 1.8 1 0 0 1 1 1 0 Apolipoprotein O ADH_N PF08240.7 EEA04848.1 - 7.1e-26 90.1 3.3 1.2e-25 89.4 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA04848.1 - 5.7e-17 61.4 0.3 8.8e-17 60.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EEA04848.1 - 0.0042 16.9 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA04848.1 - 0.017 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-RanBP PF00641.13 EEA04850.1 - 0.0021 17.0 5.4 0.0021 17.0 3.7 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Ribosomal_L30 PF00327.15 EEA04851.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e PUF PF00806.14 EEA04852.1 - 0.0084 15.5 0.1 0.33 10.5 0.1 3.7 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat His_Phos_1 PF00300.17 EEA04853.1 - 6.3e-28 97.8 0.3 1e-27 97.1 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M17 PF00883.16 EEA04854.1 - 8.7e-101 336.8 0.0 1.1e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF2719 PF10891.3 EEA04855.1 - 0.0092 15.6 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2719) PYRIN PF02758.11 EEA04855.1 - 0.09 12.4 3.2 0.36 10.5 0.0 2.8 3 1 0 3 3 3 0 PAAD/DAPIN/Pyrin domain DNA_mis_repair PF01119.14 EEA04856.1 - 3.3e-20 71.7 4.2 4.4e-19 68.0 0.5 2.7 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEA04856.1 - 3.2e-12 46.2 0.0 1.1e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA04856.1 - 2.6e-08 33.5 0.0 7.3e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ubiquitin PF00240.18 EEA04857.1 - 1.5e-71 235.7 5.2 3.4e-35 119.2 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EEA04857.1 - 6.4e-42 141.0 4.6 2.9e-20 71.7 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA04857.1 - 9.8e-15 54.5 1.0 1.1e-05 25.6 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEA04857.1 - 1.7e-10 40.7 0.0 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEA04857.1 - 9.7e-08 31.8 0.3 0.022 14.6 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA04857.1 - 2e-06 27.9 0.1 0.067 13.3 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EEA04857.1 - 5.6e-06 26.1 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 EEA04857.1 - 4.6e-05 23.3 0.0 0.53 10.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EEA04857.1 - 0.0011 18.6 0.2 2 8.2 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain USP7_C2 PF14533.1 EEA04857.1 - 0.0031 16.9 0.3 2 7.7 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 EEA04857.1 - 0.017 15.1 1.1 13 5.8 0.1 3.4 2 2 0 2 2 2 0 FERM N-terminal domain CTDII PF01556.13 EEA04857.1 - 0.017 14.9 3.5 0.83 9.5 0.2 2.3 1 1 1 2 2 2 0 DnaJ C terminal domain Plexin_cytopl PF08337.7 EEA04857.1 - 0.018 13.4 2.7 1.8 6.7 0.1 3.3 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain GABP-alpha PF11620.3 EEA04857.1 - 0.1 12.5 0.2 16 5.5 0.0 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF2207 PF09972.4 EEA04857.1 - 0.17 10.4 2.1 6.2 5.2 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 EEA04858.1 - 1e-16 60.0 29.5 2.2e-07 30.4 0.3 9.5 11 0 0 11 11 11 6 WD domain, G-beta repeat CECR6_TMEM121 PF14997.1 EEA04859.1 - 1.9e-12 47.1 6.4 5.7e-12 45.6 4.5 1.8 1 0 0 1 1 1 1 CECR6/TMEM121 family Med6 PF04934.9 EEA04860.1 - 4.6e-25 87.8 0.0 7.1e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pkinase PF00069.20 EEA04861.1 - 4.8e-77 258.6 0.0 5.4e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04861.1 - 2.3e-34 118.6 0.0 2.6e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA04861.1 - 7.9e-06 25.0 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA04861.1 - 6.5e-05 22.7 0.7 0.0079 15.9 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EEA04861.1 - 0.0018 17.6 0.2 0.0091 15.3 0.1 1.8 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 EEA04861.1 - 0.0018 17.3 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.24 EEA04862.1 - 1.1e-32 113.1 7.8 1.1e-32 113.1 5.4 4.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Yip1 PF04893.12 EEA04863.1 - 1.2e-05 24.8 6.4 1.8e-05 24.2 4.4 1.3 1 0 0 1 1 1 1 Yip1 domain Rad60-SLD PF11976.3 EEA04864.1 - 9.9e-10 37.9 0.0 4.4e-07 29.4 0.0 3.7 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like GCD14 PF08704.5 EEA04865.1 - 1.4e-64 217.9 0.3 5.2e-63 212.8 0.0 2.0 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EEA04865.1 - 2.9e-09 36.6 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA04865.1 - 4.4e-07 30.4 0.0 7.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA04865.1 - 9.6e-07 28.5 0.0 2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EEA04865.1 - 1.8e-05 23.8 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EEA04865.1 - 0.00074 18.6 0.0 0.00099 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EEA04865.1 - 0.0022 18.4 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.1 EEA04865.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_3 PF01596.12 EEA04865.1 - 0.096 11.7 0.0 0.14 11.1 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase RRM_1 PF00076.17 EEA04866.1 - 7.1e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA04866.1 - 1.1e-05 25.2 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA04866.1 - 0.042 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dus PF01207.12 EEA04868.1 - 8.6e-34 116.7 0.0 7.3e-21 74.2 0.0 3.3 3 1 0 3 3 3 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EEA04868.1 - 2.6e-05 23.7 5.9 0.038 13.6 1.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Prefoldin PF02996.12 EEA04869.1 - 3.9e-22 78.1 0.1 5.4e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Sec8_exocyst PF04048.9 EEA04869.1 - 0.042 13.4 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.5 EEA04869.1 - 0.059 13.4 0.7 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EEA04869.1 - 0.064 12.7 0.8 0.39 10.1 0.2 1.9 1 1 1 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 EEA04869.1 - 0.24 11.1 4.4 1.4 8.6 0.1 2.4 2 1 0 2 2 2 0 Prefoldin subunit LMBR1 PF04791.11 EEA04870.1 - 5.1 5.5 8.8 0.18 10.3 0.9 2.5 2 2 0 2 2 2 0 LMBR1-like membrane protein Beta-lactamase PF00144.19 EEA04871.1 - 3.9e-31 108.2 0.0 8.6e-29 100.5 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase ABC1 PF03109.11 EEA04872.1 - 1.5e-26 92.6 0.2 2.5e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EEA04872.1 - 0.00024 20.5 0.1 0.076 12.3 0.0 2.4 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EEA04872.1 - 0.00065 19.5 0.0 0.0019 17.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEA04872.1 - 0.0011 18.2 0.3 0.0023 17.1 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 EEA04872.1 - 0.023 13.8 0.0 0.06 12.4 0.0 1.7 1 1 1 2 2 2 0 Ecdysteroid kinase WaaY PF06176.6 EEA04872.1 - 0.032 13.4 0.1 0.061 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Gcd10p PF04189.8 EEA04873.1 - 2.6e-21 76.0 1.4 3.6e-20 72.3 0.1 2.9 1 1 0 1 1 1 1 Gcd10p family PAF-AH_p_II PF03403.8 EEA04873.1 - 0.02 13.2 1.5 0.032 12.5 1.1 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Podoplanin PF05808.6 EEA04874.1 - 2.2 7.8 3.9 3.4 7.1 2.7 1.3 1 0 0 1 1 1 0 Podoplanin Peptidase_S64 PF08192.6 EEA04874.1 - 2.2 6.4 11.3 3.2 5.9 7.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_60s PF00428.14 EEA04875.1 - 1.3e-18 67.1 0.9 1.7e-18 66.7 0.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein PDZ_2 PF13180.1 EEA04876.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.7 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EEA04876.1 - 0.0035 17.3 0.0 0.007 16.3 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EEA04876.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DUF1048 PF06304.6 EEA04876.1 - 0.13 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) UCH PF00443.24 EEA04877.1 - 2e-24 86.1 0.8 3.2e-24 85.4 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA04877.1 - 8.6e-10 38.5 6.1 1.9e-09 37.4 4.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Topoisom_I PF01028.15 EEA04877.1 - 0.022 13.8 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core SET PF00856.23 EEA04878.1 - 1.1e-05 25.7 0.6 0.0005 20.4 0.0 3.2 2 1 0 2 2 2 1 SET domain Actin PF00022.14 EEA04879.1 - 6.3e-127 423.2 0.0 7.7e-127 422.9 0.0 1.0 1 0 0 1 1 1 1 Actin Band_7 PF01145.20 EEA04880.1 - 7.8e-24 84.5 0.6 7.8e-24 84.5 0.4 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.3 EEA04880.1 - 0.053 13.5 1.1 0.095 12.7 0.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Sin3_corepress PF08295.7 EEA04881.1 - 3.7e-38 129.3 2.5 7.3e-38 128.3 0.2 2.5 2 1 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.16 EEA04881.1 - 8.8e-31 105.2 2.2 9.2e-15 54.0 0.0 3.5 3 0 0 3 3 3 2 Paired amphipathic helix repeat DAD PF02109.11 EEA04882.1 - 2.8e-27 94.9 4.6 3.8e-27 94.5 3.2 1.1 1 0 0 1 1 1 1 DAD family Pkinase PF00069.20 EEA04884.1 - 4.9e-34 117.6 2.6 7.6e-34 117.0 1.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04884.1 - 1.7e-19 69.8 0.2 3e-19 69.0 0.2 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA04884.1 - 2.3e-05 23.5 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EEA04884.1 - 0.00013 21.2 2.7 0.00097 18.3 0.1 2.7 2 1 1 3 3 3 1 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 EEA04884.1 - 0.00019 20.8 0.2 0.00034 20.0 0.1 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EEA04884.1 - 0.00062 18.8 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA04884.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEA04884.1 - 0.057 12.7 2.0 0.15 11.4 1.4 1.7 1 1 0 1 1 1 0 RIO1 family DUF1510 PF07423.6 EEA04885.1 - 0.0013 18.1 4.8 0.0016 17.8 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Gag_spuma PF03276.9 EEA04885.1 - 0.0047 15.3 4.2 0.0055 15.0 2.9 1.0 1 0 0 1 1 1 1 Spumavirus gag protein Neur_chan_memb PF02932.11 EEA04885.1 - 0.0056 16.6 8.1 0.0056 16.6 5.6 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.10 EEA04885.1 - 0.029 13.0 2.8 0.033 12.9 1.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 EEA04885.1 - 0.14 10.3 4.9 0.15 10.2 3.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paramyxo_ncap PF00973.14 EEA04885.1 - 0.2 10.3 6.6 0.22 10.1 4.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LicD PF04991.8 EEA04885.1 - 0.47 10.5 9.4 0.5 10.4 6.5 1.1 1 0 0 1 1 1 0 LicD family DUF262 PF03235.9 EEA04885.1 - 0.65 9.9 6.1 0.69 9.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Zip PF02535.17 EEA04885.1 - 0.67 8.9 3.3 0.81 8.6 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4288 PF14119.1 EEA04885.1 - 0.67 10.1 3.7 0.43 10.7 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4288) DUF4220 PF13968.1 EEA04885.1 - 3.3 6.7 5.9 3.7 6.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Cellulose_synt PF03552.9 EEA04885.1 - 4.1 5.5 6.0 4.6 5.4 4.2 1.0 1 0 0 1 1 1 0 Cellulose synthase THDPS_M PF14789.1 EEA04886.1 - 0.0024 17.7 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Tetrahydrodipicolinate N-succinyltransferase middle Glycos_transf_4 PF00953.16 EEA04887.1 - 1.4e-35 122.4 14.5 1.4e-35 122.4 10.1 3.3 4 0 0 4 4 4 1 Glycosyl transferase family 4 Thioredoxin PF00085.15 EEA04888.1 - 3.6e-11 42.6 0.1 5.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1510 PF07423.6 EEA04888.1 - 3.3e-06 26.6 19.7 4.7e-06 26.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EEA04888.1 - 4.6e-05 23.2 17.8 8.3e-05 22.4 12.3 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Thioredoxin_6 PF13848.1 EEA04888.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Ycf1 PF05758.7 EEA04888.1 - 0.00011 20.0 5.0 0.00014 19.7 3.5 1.1 1 0 0 1 1 1 1 Ycf1 DUF4366 PF14283.1 EEA04888.1 - 0.00033 20.1 3.3 0.00033 20.1 2.3 2.4 1 1 1 2 2 1 1 Domain of unknown function (DUF4366) CDC45 PF02724.9 EEA04888.1 - 0.011 13.7 31.2 0.015 13.3 21.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEA04888.1 - 0.012 13.5 42.7 0.016 13.1 29.6 1.1 1 0 0 1 1 1 0 Nop14-like family Thioredoxin_2 PF13098.1 EEA04888.1 - 0.014 15.6 0.4 0.11 12.6 0.3 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Rad17 PF03215.10 EEA04888.1 - 0.041 12.5 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zip PF02535.17 EEA04888.1 - 0.048 12.6 1.8 0.069 12.1 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 EEA04888.1 - 0.057 13.2 1.8 0.078 12.7 1.2 1.3 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 EEA04888.1 - 0.1 11.0 40.0 0.14 10.5 27.7 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EEA04888.1 - 0.13 11.4 24.3 0.18 10.9 16.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 EEA04888.1 - 0.61 9.0 34.9 0.83 8.6 24.2 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid PF03115.9 EEA04888.1 - 0.62 8.2 12.9 0.84 7.8 8.9 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Raftlin PF15250.1 EEA04888.1 - 0.66 8.4 6.8 0.91 7.9 4.7 1.1 1 0 0 1 1 1 0 Raftlin SID-1_RNA_chan PF13965.1 EEA04888.1 - 0.95 7.5 5.1 2.1 6.4 3.5 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4045 PF13254.1 EEA04888.1 - 1.3 8.2 11.6 1.8 7.7 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF908 PF06012.7 EEA04888.1 - 2 7.6 6.4 4 6.6 4.4 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) SDA1 PF05285.7 EEA04888.1 - 3.5 6.8 44.8 4.9 6.3 31.1 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.1 EEA04888.1 - 3.7 6.9 21.1 5.7 6.3 14.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 EEA04888.1 - 3.9 6.1 33.6 7.3 5.2 23.3 1.4 1 0 0 1 1 1 0 Paf1 CKAP2_C PF15297.1 EEA04888.1 - 6.6 5.4 15.1 13 4.5 10.5 1.5 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Mpp10 PF04006.7 EEA04888.1 - 8.3 4.6 45.6 11 4.2 31.6 1.1 1 0 0 1 1 1 0 Mpp10 protein LSM PF01423.17 EEA04889.1 - 3.8e-15 55.1 2.6 5e-15 54.8 1.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA04889.1 - 0.0012 18.7 0.2 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EEA04889.1 - 0.024 14.3 0.1 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Ribosomal_S13_N PF08069.7 EEA04890.1 - 1.1e-27 95.6 0.5 2.2e-27 94.6 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEA04890.1 - 1.5e-20 72.6 0.2 2.1e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 DUF1489 PF07370.6 EEA04890.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) RRM_1 PF00076.17 EEA04891.1 - 4.7e-33 112.6 0.3 3e-15 55.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA04891.1 - 1.2e-29 102.1 0.0 4.2e-14 52.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA04891.1 - 2.6e-15 55.9 1.0 8.9e-08 31.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endonuclease_NS PF01223.18 EEA04892.1 - 3.9e-35 121.3 0.0 1.6e-34 119.3 0.0 1.8 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease HALZ PF02183.13 EEA04893.1 - 0.00043 19.9 4.8 0.00087 18.9 3.3 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper ADIP PF11559.3 EEA04893.1 - 0.0012 18.7 4.0 0.007 16.2 2.8 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EEA04893.1 - 0.014 15.6 1.8 0.083 13.2 1.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) UPF0242 PF06785.6 EEA04893.1 - 0.3 9.7 2.4 0.51 8.9 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF1837 PF08878.6 EEA04895.1 - 0.017 14.7 0.1 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) Leader_Trp PF08255.6 EEA04895.1 - 0.15 11.7 1.0 0.34 10.6 0.7 1.6 1 0 0 1 1 1 0 Trp-operon Leader Peptide EF-hand_7 PF13499.1 EEA04896.1 - 0.0019 18.3 0.1 0.42 10.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA04896.1 - 0.0085 15.6 0.1 0.15 11.6 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair Zip PF02535.17 EEA04897.1 - 1.6e-37 129.2 11.8 1.8e-37 129.0 8.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-CCHC PF00098.18 EEA04898.1 - 0.04 13.8 0.6 0.04 13.8 0.4 3.4 3 0 0 3 3 3 0 Zinc knuckle Viral_NABP PF05515.6 EEA04898.1 - 2 8.7 7.0 5.8 7.2 3.6 2.2 2 0 0 2 2 2 0 Viral nucleic acid binding Chromo PF00385.19 EEA04899.1 - 9e-12 44.4 1.3 1.8e-11 43.5 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RWD PF05773.17 EEA04900.1 - 9e-14 51.3 1.1 1.9e-13 50.2 0.8 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EEA04900.1 - 0.0077 15.6 0.1 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Elf1 PF05129.8 EEA04901.1 - 8.1e-28 95.9 2.4 1.3e-27 95.3 1.6 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 EEA04901.1 - 0.00092 19.4 0.1 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar FdhE PF04216.7 EEA04901.1 - 0.0055 16.4 0.1 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation DNA_methylase PF00145.12 EEA04902.1 - 2.9e-26 92.3 0.1 4.5e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase FCH PF00611.18 EEA04903.1 - 2e-10 40.6 0.1 2e-10 40.6 0.1 4.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Nipped-B_C PF12830.2 EEA04904.1 - 2.3e-09 37.1 0.8 1.4e-08 34.6 0.3 2.7 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT PF02985.17 EEA04904.1 - 1.6e-06 27.6 0.3 2 8.7 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat PHD PF00628.24 EEA04904.1 - 1.9e-06 27.4 8.8 1.9e-06 27.4 6.1 2.5 2 0 0 2 2 2 1 PHD-finger HEAT_2 PF13646.1 EEA04904.1 - 1.6e-05 25.1 0.1 0.0045 17.2 0.0 2.8 1 1 1 2 2 2 2 HEAT repeats PHD_2 PF13831.1 EEA04904.1 - 0.019 14.2 8.1 0.0064 15.7 3.0 2.2 2 0 0 2 2 2 0 PHD-finger HEAT_EZ PF13513.1 EEA04904.1 - 0.12 12.8 0.8 0.7 10.4 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat SNF2_N PF00176.18 EEA04905.1 - 3.6e-73 245.9 1.5 5.9e-73 245.2 1.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA04905.1 - 6.6e-09 35.5 0.0 2.4e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EEA04905.1 - 9.6e-09 34.7 6.3 2.3e-08 33.5 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA04905.1 - 2.6e-08 33.7 9.0 5.4e-08 32.7 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA04905.1 - 9.1e-08 31.8 9.9 1.9e-07 30.8 6.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEA04905.1 - 2.5e-07 30.4 7.5 4.8e-07 29.4 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA04905.1 - 4.5e-06 26.2 8.2 1e-05 25.1 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA04905.1 - 8.1e-05 22.2 5.6 0.00023 20.8 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEA04905.1 - 0.00034 20.2 6.6 0.00069 19.2 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 EEA04905.1 - 0.068 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain zf-MIZ PF02891.15 EEA04905.1 - 0.17 11.4 6.3 0.38 10.3 4.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EEA04905.1 - 0.23 11.0 5.4 0.49 10.0 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DEAD PF00270.24 EEA04906.1 - 8.6e-21 74.1 0.0 3.2e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA04906.1 - 0.00053 19.7 0.2 0.0017 18.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF935 PF06074.7 EEA04906.1 - 0.0038 16.0 0.4 0.0063 15.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF935) AAA_30 PF13604.1 EEA04906.1 - 0.37 10.3 0.0 3 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FHA PF00498.21 EEA04908.1 - 2.5e-18 65.9 0.3 2.5e-18 65.9 0.2 3.2 4 0 0 4 4 4 1 FHA domain ERM PF00769.14 EEA04908.1 - 1.2e-06 28.2 8.7 2.5e-06 27.1 6.0 1.6 1 0 0 1 1 1 1 Ezrin/radixin/moesin family LysM PF01476.15 EEA04908.1 - 0.39 10.6 3.8 24 4.8 0.1 4.2 4 0 0 4 4 4 0 LysM domain PspB PF06667.7 EEA04908.1 - 1.4 8.8 3.8 1.8 8.5 0.2 2.6 2 0 0 2 2 2 0 Phage shock protein B V_ATPase_I PF01496.14 EEA04908.1 - 5.4 4.7 16.9 27 2.4 11.7 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 EEA04908.1 - 9.2 6.0 14.6 12 5.7 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Glycos_transf_2 PF00535.21 EEA04909.1 - 4.2e-32 111.1 0.0 5.2e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EEA04909.1 - 2.3e-12 46.5 0.0 3.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EEA04909.1 - 1.8e-11 44.2 0.0 2.2e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA04909.1 - 0.00082 18.6 0.0 0.0017 17.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 PITH PF06201.8 EEA04910.1 - 6.7e-28 97.3 2.5 9.9e-28 96.8 1.7 1.2 1 0 0 1 1 1 1 PITH domain CAP PF00188.21 EEA04911.1 - 1.3e-20 74.1 2.5 1.3e-20 74.1 1.7 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family AAA PF00004.24 EEA04912.1 - 2.7e-84 279.9 0.0 1.4e-48 164.3 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA04912.1 - 2.8e-12 46.2 0.0 4.1e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA04912.1 - 2.3e-11 44.0 0.2 1.2e-05 25.3 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EEA04912.1 - 3e-10 39.6 0.2 0.00025 20.7 0.2 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EEA04912.1 - 3.5e-10 40.1 0.1 0.00058 20.0 0.0 5.2 3 2 2 5 5 4 1 AAA domain AAA_17 PF13207.1 EEA04912.1 - 2.4e-09 38.0 0.3 7.8e-05 23.4 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EEA04912.1 - 4e-09 36.6 0.0 3.8e-05 23.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EEA04912.1 - 7.8e-09 34.7 0.2 0.0015 17.3 0.0 2.9 3 0 0 3 3 3 2 TIP49 C-terminus AAA_25 PF13481.1 EEA04912.1 - 1.1e-08 34.7 2.9 0.21 10.9 0.0 4.3 2 2 2 4 4 4 3 AAA domain IstB_IS21 PF01695.12 EEA04912.1 - 3.2e-08 33.2 0.5 0.0044 16.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EEA04912.1 - 5.3e-08 32.6 0.0 0.0041 16.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEA04912.1 - 6.3e-08 32.5 0.0 0.0081 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEA04912.1 - 1.9e-07 30.4 0.0 0.00039 19.5 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EEA04912.1 - 1.5e-06 28.1 0.0 0.00071 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA04912.1 - 1.4e-05 25.3 3.4 0.034 14.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain ABC_tran PF00005.22 EEA04912.1 - 2.2e-05 24.7 0.4 0.0063 16.8 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EEA04912.1 - 3e-05 24.1 0.0 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EEA04912.1 - 3e-05 23.2 0.9 0.021 13.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EEA04912.1 - 4.4e-05 23.1 0.3 0.022 14.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EEA04912.1 - 4.6e-05 23.1 0.1 0.1 12.2 0.0 3.4 2 1 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EEA04912.1 - 8.1e-05 22.2 0.0 0.48 10.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEA04912.1 - 0.00025 20.8 0.1 0.1 12.2 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 EEA04912.1 - 0.00046 20.1 0.2 0.056 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EEA04912.1 - 0.00061 19.0 0.1 1.5 8.0 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.21 EEA04912.1 - 0.00098 18.6 0.0 0.14 11.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EEA04912.1 - 0.0017 17.9 0.2 0.091 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EEA04912.1 - 0.0019 17.3 0.0 0.59 9.2 0.0 3.2 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.13 EEA04912.1 - 0.0029 17.1 0.0 0.063 12.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EEA04912.1 - 0.0038 16.7 0.1 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.9 EEA04912.1 - 0.0055 15.7 0.0 0.18 10.7 0.0 3.0 3 0 0 3 3 3 1 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EEA04912.1 - 0.0091 16.0 0.3 0.68 9.9 0.0 3.3 3 1 0 4 4 3 1 Sigma-54 interaction domain UPF0079 PF02367.12 EEA04912.1 - 0.012 15.2 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EEA04912.1 - 0.018 13.8 0.0 0.2 10.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EEA04912.1 - 0.029 13.3 0.0 0.17 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 EEA04912.1 - 0.039 12.9 0.0 8.1 5.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EEA04912.1 - 0.042 12.6 0.8 0.15 10.9 0.0 2.3 3 0 0 3 3 2 0 NB-ARC domain NTPase_1 PF03266.10 EEA04912.1 - 0.09 12.4 0.0 5.8 6.5 0.0 3.0 2 0 0 2 2 2 0 NTPase ResIII PF04851.10 EEA04912.1 - 0.092 12.5 0.0 23 4.7 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 EEA04912.1 - 0.094 12.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.7 EEA04912.1 - 0.12 12.0 0.0 17 4.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.1 EEA04912.1 - 0.17 11.4 0.0 8 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RIO1 PF01163.17 EEA04913.1 - 2.8e-52 176.8 0.7 3.1e-28 98.4 0.0 3.0 3 1 1 4 4 4 2 RIO1 family M60-like PF13402.1 EEA04914.1 - 1.5e-45 155.4 0.0 3.7e-38 131.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M60-like family S-AdoMet_synt_N PF00438.15 EEA04914.1 - 0.024 14.8 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain PH PF00169.24 EEA04916.1 - 7.3e-21 74.3 0.2 8.5e-21 74.1 0.1 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EEA04916.1 - 5.5e-09 36.2 1.8 1e-07 32.1 1.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EEA04916.1 - 1.7e-05 24.6 0.1 4.7e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 EEA04916.1 - 0.00011 22.1 0.1 0.00017 21.6 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EEA04916.1 - 0.075 13.1 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Enolase_C PF00113.17 EEA04917.1 - 5.6e-140 465.4 0.0 7e-140 465.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEA04917.1 - 1.3e-55 186.9 0.1 2e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EEA04917.1 - 0.00099 19.5 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EEA04917.1 - 0.0098 14.8 0.1 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.11 EEA04917.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.1 EEA04917.1 - 0.047 13.6 0.3 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like Abi PF02517.11 EEA04918.1 - 1.3e-13 50.8 3.7 1.3e-13 50.8 2.6 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity DUF572 PF04502.8 EEA04919.1 - 0.088 12.0 12.1 0.04 13.1 3.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF572) Lar_restr_allev PF14354.1 EEA04919.1 - 0.11 12.7 2.1 2.8 8.3 1.4 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-CHY PF05495.7 EEA04919.1 - 0.82 9.8 5.8 0.36 11.0 2.3 1.7 2 0 0 2 2 2 0 CHY zinc finger RNA_POL_M_15KD PF02150.11 EEA04919.1 - 8.2 6.2 9.4 2.4 7.9 0.5 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Ste5 PF11610.3 EEA04920.1 - 0.057 12.9 8.2 0.28 10.7 0.1 4.3 4 0 0 4 4 4 0 Scaffold protein Ste5-Fus5 binding region PH PF00169.24 EEA04921.1 - 0.043 14.0 1.4 0.19 11.9 0.3 2.4 2 1 0 2 2 2 0 PH domain EF-hand_8 PF13833.1 EEA04922.1 - 1.9e-07 30.5 0.4 3.7e-06 26.4 0.1 2.6 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA04922.1 - 6e-07 28.3 1.6 1e-06 27.5 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EEA04922.1 - 3.8e-06 26.3 1.8 8.2e-06 25.2 0.4 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EEA04922.1 - 9.3e-05 22.4 1.9 0.00074 19.6 1.3 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EEA04922.1 - 0.00035 19.7 1.2 0.0019 17.4 0.5 2.4 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.12 EEA04923.1 - 4.9e-68 229.2 0.1 6.1e-68 228.8 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EEA04923.1 - 1.2e-05 24.7 0.0 3.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EEA04923.1 - 0.0068 15.8 0.0 1.5 8.2 0.0 2.6 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EEA04923.1 - 0.024 14.1 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NAP PF00956.13 EEA04923.1 - 0.031 13.3 0.8 0.049 12.7 0.6 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF87 PF01935.12 EEA04923.1 - 0.048 13.4 0.2 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EEA04923.1 - 0.095 11.5 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EEA04923.1 - 0.29 11.4 1.6 12 6.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Neuregulin PF02158.10 EEA04923.1 - 0.84 8.3 2.8 4 6.1 0.7 1.9 1 1 1 2 2 2 0 Neuregulin family TBPIP PF07106.8 EEA04925.1 - 0.002 17.6 7.2 0.3 10.6 0.5 2.4 2 1 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vac_Fusion PF02346.11 EEA04925.1 - 0.033 13.6 5.9 0.036 13.4 0.3 3.2 3 2 1 4 4 4 0 Chordopoxvirus fusion protein PRANC PF09372.5 EEA04925.1 - 0.1 12.5 11.3 0.96 9.4 1.6 2.5 2 0 0 2 2 2 0 PRANC domain CENP-F_leu_zip PF10473.4 EEA04925.1 - 0.21 11.4 4.8 3.7 7.4 0.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-SNARE PF05008.10 EEA04925.1 - 0.75 9.9 5.7 2 8.6 0.3 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.4 EEA04925.1 - 0.8 9.8 5.3 13 5.9 0.1 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 EEA04925.1 - 1.5 8.2 4.9 3.8 6.9 0.3 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prefoldin_2 PF01920.15 EEA04925.1 - 5.8 6.7 8.3 4.8 7.0 0.2 3.2 3 1 0 3 3 3 0 Prefoldin subunit Cpn60_TCP1 PF00118.19 EEA04926.1 - 1e-128 430.0 17.2 1.5e-128 429.5 11.9 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LETM1 PF07766.8 EEA04927.1 - 3e-56 190.4 3.2 3.9e-56 190.0 2.2 1.0 1 0 0 1 1 1 1 LETM1-like protein Barstar PF01337.13 EEA04927.1 - 0.0085 15.9 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Barstar (barnase inhibitor) Las1 PF04031.8 EEA04928.1 - 8e-42 142.5 0.2 1.4e-41 141.6 0.2 1.4 1 0 0 1 1 1 1 Las1-like EntA_Immun PF08951.5 EEA04928.1 - 0.23 11.6 0.0 0.23 11.6 0.0 4.6 5 1 0 5 5 5 0 Enterocin A Immunity Gpi1 PF05024.10 EEA04929.1 - 3.7e-38 131.0 24.2 1.4e-37 129.1 16.8 2.1 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) NUC153 PF08159.7 EEA04930.1 - 4.8e-12 45.2 7.9 2.6e-07 30.0 0.0 3.8 3 0 0 3 3 3 3 NUC153 domain tRNA-Thr_ED PF08915.6 EEA04931.1 - 0.057 13.3 0.1 0.15 12.0 0.0 1.7 2 1 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase zf-CCCH_2 PF14608.1 EEA04931.1 - 3.8 7.6 18.7 8.3 6.5 2.4 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Proteasome PF00227.21 EEA04932.1 - 1.2e-55 187.7 0.7 1.7e-55 187.2 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA04932.1 - 1.7e-14 52.7 0.0 3.5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cache_2 PF08269.6 EEA04932.1 - 0.039 13.9 1.3 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Cache domain SNARE PF05739.14 EEA04933.1 - 1.4e-11 43.8 11.6 6e-08 32.2 3.0 2.4 2 0 0 2 2 2 2 SNARE domain Sec20 PF03908.8 EEA04933.1 - 0.0062 16.2 9.0 0.14 11.9 1.4 2.7 2 1 0 2 2 2 2 Sec20 NPV_P10 PF05531.7 EEA04933.1 - 0.011 15.9 12.9 0.037 14.2 2.0 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.3 EEA04933.1 - 0.014 15.4 5.7 0.23 11.5 0.3 3.2 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.7 EEA04933.1 - 0.02 14.6 8.9 0.24 11.2 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TBCA PF02970.11 EEA04933.1 - 0.045 13.8 1.1 0.045 13.8 0.8 2.5 2 0 0 2 2 2 0 Tubulin binding cofactor A Laminin_II PF06009.7 EEA04933.1 - 0.05 13.3 11.0 0.37 10.5 1.6 2.4 2 0 0 2 2 2 0 Laminin Domain II UPF0231 PF06062.6 EEA04933.1 - 0.068 13.0 4.7 0.27 11.1 0.0 2.9 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0231) Syntaxin-6_N PF09177.6 EEA04933.1 - 0.092 13.1 8.3 0.12 12.7 2.2 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal YojJ PF10372.4 EEA04933.1 - 0.12 12.2 2.9 12 5.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus COG2 PF06148.6 EEA04933.1 - 0.15 11.8 8.8 0.12 12.2 1.3 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Colicin_D PF11429.3 EEA04933.1 - 0.29 11.3 4.5 6.8 6.9 0.2 2.4 2 0 0 2 2 2 0 Colicin D BLOC1_2 PF10046.4 EEA04933.1 - 0.35 11.0 16.5 0.6 10.2 0.9 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SPX PF03105.14 EEA04933.1 - 0.48 10.1 16.4 0.34 10.6 8.2 2.0 1 1 1 2 2 2 0 SPX domain Uds1 PF15456.1 EEA04933.1 - 2.2 8.3 8.6 1.3 9.0 1.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DUF4407 PF14362.1 EEA04933.1 - 6 5.7 8.4 5.6 5.8 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 EEA04933.1 - 7 6.4 12.4 1.3 8.8 0.3 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) DUF4446 PF14584.1 EEA04933.1 - 9.4 6.0 10.1 5.6 6.7 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) Isy1 PF06246.7 EEA04935.1 - 1.8e-48 165.2 3.8 2.3e-48 164.8 2.7 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DUF848 PF05852.6 EEA04935.1 - 0.063 13.1 1.4 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FbpA PF05833.6 EEA04936.1 - 1.8e-24 86.1 12.3 2.4e-17 62.6 0.1 2.7 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EEA04936.1 - 8e-23 80.1 0.4 1.6e-21 75.9 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 EEA04936.1 - 4e-19 68.2 0.0 1.3e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) Ras PF00071.17 EEA04937.1 - 7.2e-14 51.4 0.1 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEA04937.1 - 2.5e-08 34.4 0.0 3e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EEA04937.1 - 0.001 18.5 0.1 0.38 10.1 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EEA04937.1 - 0.0014 17.8 0.0 0.15 11.2 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA04937.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EEA04937.1 - 0.039 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EEA04937.1 - 0.05 13.4 0.6 1.2 8.9 0.0 2.7 4 0 0 4 4 4 0 Dynamin family Gar1 PF04410.9 EEA04938.1 - 3.3e-39 133.8 2.3 3.3e-39 133.8 1.6 1.5 1 1 1 2 2 2 2 Gar1/Naf1 RNA binding region HORMA PF02301.13 EEA04939.1 - 1.3e-49 168.5 1.0 2.7e-49 167.4 0.1 1.8 2 0 0 2 2 2 1 HORMA domain EAP30 PF04157.11 EEA04939.1 - 0.043 12.9 0.1 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family DUF877 PF05943.7 EEA04939.1 - 0.089 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF877) PRP3 PF08572.5 EEA04940.1 - 1.4e-51 175.0 3.7 1.4e-51 175.0 2.6 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EEA04940.1 - 5.7e-31 106.8 0.4 5.7e-31 106.8 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Nol1_Nop2_Fmu PF01189.12 EEA04941.1 - 2e-18 66.7 0.0 4.4e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family bPH_3 PF14470.1 EEA04941.1 - 0.82 9.9 8.5 0.39 10.9 0.3 2.6 2 0 0 2 2 2 0 Bacterial PH domain CTP_synth_N PF06418.9 EEA04943.1 - 6.7e-113 376.3 0.0 1.1e-112 375.6 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEA04943.1 - 6.2e-44 149.7 0.0 1.6e-43 148.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEA04943.1 - 1e-06 28.3 0.2 0.08 12.3 0.2 3.3 2 1 0 2 2 2 2 Peptidase C26 CbiA PF01656.18 EEA04943.1 - 0.0004 19.8 0.0 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EEA04943.1 - 0.11 11.2 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein SNARE_assoc PF09335.6 EEA04944.1 - 0.0053 16.9 1.0 0.0053 16.9 0.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2777 PF10949.3 EEA04944.1 - 0.011 15.4 0.1 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) SUR7 PF06687.7 EEA04944.1 - 0.02 14.4 14.6 0.05 13.1 2.7 2.1 1 1 0 2 2 2 0 SUR7/PalI family DUF2207 PF09972.4 EEA04944.1 - 4.4 5.7 12.7 4.9e+02 -1.0 8.8 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytochrom_B561 PF03188.11 EEA04945.1 - 0.055 13.3 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 CactinC_cactus PF09732.4 EEA04946.1 - 1.7e-35 121.3 8.9 1.7e-35 121.2 4.5 2.3 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EEA04946.1 - 0.00044 19.5 9.6 0.024 13.9 3.6 2.6 2 1 0 2 2 2 2 Conserved mid region of cactin SH PF01445.12 EEA04946.1 - 0.072 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein DJ-1_PfpI PF01965.19 EEA04950.1 - 2.5e-20 72.4 0.2 3.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEA04950.1 - 9.9e-12 44.4 0.0 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase MORN PF02493.15 EEA04951.1 - 4.9e-65 211.5 68.6 9.8e-09 34.4 1.0 12.7 13 0 0 13 13 13 12 MORN repeat Aa_trans PF01490.13 EEA04952.1 - 8.1e-37 126.6 32.9 1.7e-36 125.6 22.8 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 EEA04953.1 - 1.9e-27 95.8 25.6 2.8e-27 95.2 17.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-CW PF07496.10 EEA04954.1 - 4.6e-16 58.2 4.3 1.6e-15 56.5 3.0 2.0 1 0 0 1 1 1 1 CW-type Zinc Finger Flavodoxin_NdrI PF07972.6 EEA04954.1 - 0.47 10.3 7.2 1.8 8.4 1.0 3.5 2 0 0 2 2 2 0 NrdI Flavodoxin like OpgC_C PF10129.4 EEA04955.1 - 0.11 11.1 0.1 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 OpgC protein IF-2B PF01008.12 EEA04956.1 - 8.7e-38 129.9 0.0 1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family L27_N PF09060.5 EEA04956.1 - 0.12 12.2 0.1 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 L27_N DUF1967 PF09269.6 EEA04957.1 - 0.074 12.7 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) DUF3407 PF11887.3 EEA04958.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Ribosomal_L3 PF00297.17 EEA04959.1 - 1.5e-107 358.9 3.5 1.8e-107 358.6 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3586 PF12131.3 EEA04959.1 - 0.0081 16.1 0.0 0.033 14.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Yip1 PF04893.12 EEA04960.1 - 1.1e-06 28.2 17.7 1.6e-06 27.7 12.1 1.3 1 1 0 1 1 1 1 Yip1 domain Robl_LC7 PF03259.12 EEA04962.1 - 3.1e-10 39.4 0.0 4.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Myb_DNA-bind_3 PF12776.2 EEA04963.1 - 0.018 15.6 5.1 0.018 15.6 3.6 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HNH PF01844.18 EEA04965.1 - 7.6 6.4 9.5 0.33 10.8 1.3 2.7 3 0 0 3 3 3 0 HNH endonuclease Mod_r PF07200.8 EEA04966.1 - 0.083 12.8 7.3 0.26 11.2 0.8 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ZYG-11_interact PF05884.7 EEA04967.1 - 0.62 9.0 0.7 2.3 7.2 0.5 2.0 1 0 0 1 1 1 0 Interactor of ZYG-11 Spore_YunB PF09560.5 EEA04968.1 - 0.0015 18.2 6.4 21 4.9 0.0 6.4 3 2 4 7 7 7 3 Sporulation protein YunB (Spo_YunB) Nuc_N PF14448.1 EEA04970.1 - 0.18 11.3 0.0 0.58 9.7 0.0 1.9 1 0 0 1 1 1 0 Nuclease N terminal CBFB_NFYA PF02045.10 EEA04970.1 - 2.2 8.9 5.2 26 5.4 0.4 3.6 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B NDK PF00334.14 EEA04972.1 - 4.4e-46 156.0 0.0 7.4e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pentapeptide_3 PF13576.1 EEA04972.1 - 0.087 12.7 4.2 14 5.6 2.8 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) HMA PF00403.21 EEA04974.1 - 0.04 14.0 1.0 0.1 12.7 0.7 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain ERp29 PF07749.7 EEA04976.1 - 0.051 14.1 1.1 0.23 12.1 0.6 2.3 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Asp PF00026.18 EEA04977.1 - 9.8e-49 166.3 0.3 2.4e-46 158.4 0.2 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA04977.1 - 2.6e-05 24.2 0.0 7.3e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA04977.1 - 0.0063 16.9 0.0 1.6 9.2 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EEA04977.1 - 0.13 12.2 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Tcf25 PF04910.9 EEA04978.1 - 2.5e-65 220.7 7.1 2.5e-65 220.7 4.9 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 PRELI PF04707.9 EEA04979.1 - 1.8e-33 115.3 0.1 3.3e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 PRELI-like family MatP PF06303.7 EEA04979.1 - 0.047 13.5 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome DUF2765 PF10963.3 EEA04979.1 - 0.2 11.5 2.8 1.7 8.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2765) zf-HIT PF04438.11 EEA04980.1 - 2.9e-05 23.5 18.3 8.2e-05 22.1 12.7 1.8 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.8 EEA04980.1 - 0.04 11.5 1.5 0.049 11.3 1.1 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF310 PF03750.8 EEA04980.1 - 0.15 12.2 0.7 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF310) zf-CCCH PF00642.19 EEA04981.1 - 6.1e-05 22.5 3.9 0.004 16.8 0.1 4.2 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DndB PF14072.1 EEA04982.1 - 0.015 14.4 1.0 0.019 14.0 0.7 1.2 1 0 0 1 1 1 0 DNA-sulfur modification-associated Gemini_AL1_M PF08283.6 EEA04982.1 - 0.023 14.5 0.3 0.036 13.8 0.2 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain Acyl-CoA_ox_N PF14749.1 EEA04982.1 - 0.065 13.5 0.0 0.091 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal EF-hand_2 PF09068.6 EEA04982.1 - 0.068 13.2 0.2 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 EF hand ING PF12998.2 EEA04982.1 - 0.091 13.0 0.1 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4149 PF13664.1 EEA04983.1 - 0.052 13.6 0.3 0.052 13.6 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4231 PF14015.1 EEA04983.1 - 0.18 11.7 1.7 0.2 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MpPF26 PF07666.6 EEA04983.1 - 0.19 11.6 1.6 0.27 11.1 1.1 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF2721 PF11026.3 EEA04983.1 - 0.47 10.0 3.8 0.86 9.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4013 PF13197.1 EEA04983.1 - 1.2 8.4 5.5 8.3 5.7 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) Synaptobrevin PF00957.16 EEA04984.1 - 4.7e-09 35.7 0.6 6e-09 35.3 0.5 1.1 1 0 0 1 1 1 1 Synaptobrevin Sec8_exocyst PF04048.9 EEA04984.1 - 0.06 12.9 0.3 0.066 12.8 0.2 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Psu PF07455.6 EEA04984.1 - 0.088 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) DUF2937 PF11157.3 EEA04984.1 - 0.14 11.4 0.6 0.62 9.3 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF3883 PF13020.1 EEA04985.1 - 1.3e-21 76.0 0.2 4e-21 74.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Steroid_dh PF02544.11 EEA04986.1 - 5.7e-16 58.6 9.2 5.7e-16 58.6 6.4 2.2 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PufQ PF05398.6 EEA04986.1 - 0.25 11.3 2.0 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF4564 PF15169.1 EEA04986.1 - 8.8 6.0 6.9 3 7.5 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4564) RRM_1 PF00076.17 EEA04987.1 - 8.5e-15 54.1 0.0 1.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA04987.1 - 1.6e-14 53.6 0.0 2.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA04987.1 - 2.9e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Actin PF00022.14 EEA04988.1 - 2.5e-74 250.0 0.0 3.7e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 Actin CS PF04969.11 EEA04989.1 - 6.2e-10 39.4 0.0 2.1e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 CS domain UMPH-1 PF05822.7 EEA04989.1 - 0.035 13.4 1.0 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Guanylate_cyc PF00211.15 EEA04990.1 - 1.4e-32 112.5 0.0 2.6e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EF-hand_1 PF00036.27 EEA04990.1 - 0.031 13.5 0.0 0.51 9.7 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EEA04990.1 - 0.064 13.4 0.1 0.064 13.4 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair TPR_16 PF13432.1 EEA04991.1 - 3.4e-10 40.3 0.1 0.016 15.9 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA04991.1 - 1.1e-09 37.7 21.2 0.00043 19.8 0.4 6.9 6 2 2 8 8 8 3 TPR repeat TPR_12 PF13424.1 EEA04991.1 - 9.2e-08 31.9 13.4 0.0085 16.0 0.0 6.8 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA04991.1 - 3.5e-07 29.5 12.3 1 9.3 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA04991.1 - 5.3e-06 26.6 2.0 0.26 11.6 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA04991.1 - 7.2e-06 25.5 21.9 0.41 10.6 0.0 9.3 11 0 0 11 11 11 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA04991.1 - 2.3e-05 24.4 19.8 0.12 12.5 0.1 6.8 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EEA04991.1 - 2.5e-05 23.6 24.0 0.074 12.6 0.1 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEA04991.1 - 0.00013 22.1 7.7 11 6.6 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA04991.1 - 0.00015 22.0 0.0 4.6 8.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA04991.1 - 0.0018 18.0 0.6 4.1 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEA04991.1 - 0.021 15.0 0.4 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 EEA04991.1 - 0.058 13.6 8.2 22 5.5 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Sec62 PF03839.11 EEA04992.1 - 2.9e-22 79.1 6.2 4.1e-22 78.7 4.3 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 zf-DHHC PF01529.15 EEA04993.1 - 1e-29 103.1 18.5 1e-29 103.1 12.8 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Dymeclin PF09742.4 EEA04994.1 - 3.2e-151 504.7 30.0 3.7e-151 504.5 20.8 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Pkinase PF00069.20 EEA04995.1 - 4.1e-59 199.8 0.0 6.3e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA04995.1 - 9.8e-27 93.6 0.0 1.4e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA04995.1 - 9.9e-06 24.7 0.0 0.00061 18.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEA04995.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF663 PF04950.7 EEA04996.1 - 8.4e-69 231.7 1.4 8.4e-69 231.7 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEA04996.1 - 3.5e-19 68.1 0.0 8.1e-19 66.9 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RNA_pol_Rpc4 PF05132.9 EEA04997.1 - 1.3e-06 28.4 0.8 1.8e-05 24.7 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 DUF3439 PF11921.3 EEA04998.1 - 0.0087 15.8 5.4 0.0087 15.8 3.7 29.4 12 5 2 14 14 14 6 Domain of unknown function (DUF3439) zf-B_box PF00643.19 EEA04999.1 - 4.7e-07 29.6 6.5 4.7e-07 29.6 4.5 4.6 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.1 EEA04999.1 - 0.34 10.6 36.6 1.3 8.7 4.7 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EEA05000.1 - 1e-18 66.7 0.4 3.5e-13 48.9 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05000.1 - 1.3e-18 66.7 0.2 1.9e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05000.1 - 2.4e-07 30.4 0.7 0.0021 17.8 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMBR PF09373.5 EEA05000.1 - 0.032 14.1 1.3 0.14 12.1 0.2 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat Topoisom_bac PF01131.15 EEA05001.1 - 5.2e-94 315.3 0.0 6e-93 311.8 0.0 2.0 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EEA05001.1 - 1.3e-15 57.1 0.0 3.7e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Beta-Casp PF10996.3 EEA05002.1 - 6.8e-21 74.5 0.0 1.7e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EEA05002.1 - 2e-13 50.4 0.2 1.2e-09 38.0 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA05002.1 - 7.4e-11 41.9 0.1 5.1e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EEA05002.1 - 1.4e-09 37.5 0.1 3.1e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EEA05002.1 - 3e-05 23.7 0.1 0.0002 21.1 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain BTB PF00651.26 EEA05003.1 - 3.2e-09 36.7 0.0 6.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Med26 PF08711.6 EEA05004.1 - 1.8e-09 36.9 2.6 1.9e-09 36.9 0.7 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Cloacin_immun PF03513.9 EEA05004.1 - 0.017 15.1 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Cloacin immunity protein UPF0086 PF01868.11 EEA05004.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Epimerase PF01370.16 EEA05005.1 - 2e-25 89.6 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA05005.1 - 2.4e-21 75.7 0.0 2.1e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EEA05005.1 - 3.1e-19 68.7 0.0 5.4e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA05005.1 - 1e-17 64.7 0.0 1.7e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA05005.1 - 1.3e-07 31.0 0.0 3.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EEA05005.1 - 3.2e-06 26.2 0.0 6.6e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEA05005.1 - 0.00052 19.7 0.0 0.0029 17.2 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EEA05005.1 - 0.0017 18.2 0.1 0.022 14.6 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase WD40 PF00400.27 EEA05006.1 - 1.1e-47 158.2 14.1 7.5e-09 35.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EEA05006.1 - 5.7e-11 41.4 0.0 1.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pecanex_C PF05041.10 EEA05006.1 - 0.0054 15.7 0.3 0.0087 15.1 0.2 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Nup160 PF11715.3 EEA05006.1 - 0.014 13.5 0.0 0.72 7.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Myb_DNA-bind_6 PF13921.1 EEA05007.1 - 0.0011 19.0 0.0 0.0049 16.9 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Toprim_2 PF13155.1 EEA05007.1 - 0.033 14.5 1.1 3 8.2 0.1 3.1 3 0 0 3 3 3 0 Toprim-like SSXT PF05030.7 EEA05008.1 - 8.2e-05 22.0 0.4 0.00021 20.7 0.3 1.7 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-C2H2 PF00096.21 EEA05008.1 - 0.027 14.7 3.9 0.027 14.7 2.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA05008.1 - 0.089 13.1 3.1 0.26 11.7 2.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA05008.1 - 0.14 12.3 2.5 0.38 10.9 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EEA05008.1 - 3.9 7.6 5.9 2.4 8.3 1.8 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Orthopox_F8 PF05886.6 EEA05009.1 - 0.014 15.1 0.3 0.03 14.1 0.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Acyltransferase PF01553.16 EEA05011.1 - 4.3e-13 48.8 0.0 1.6e-12 46.9 0.0 1.9 1 1 1 2 2 2 1 Acyltransferase zf-CCCH PF00642.19 EEA05012.1 - 4.1e-06 26.3 22.4 0.00039 20.0 2.4 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA05012.1 - 0.0059 16.5 0.7 0.0059 16.5 0.5 4.3 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EEA05012.1 - 0.013 15.0 2.3 0.51 9.9 0.0 2.8 3 0 0 3 3 3 0 LRV protein FeS4 cluster Herpes_glycop_D PF01537.12 EEA05012.1 - 0.23 11.3 1.6 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus glycoprotein D/GG/GX domain Occludin_ELL PF07303.8 EEA05013.1 - 0.0004 21.0 9.5 0.0004 21.0 6.6 5.5 3 1 3 6 6 6 1 Occludin homology domain ISAV_HA PF06215.6 EEA05013.1 - 0.029 12.7 0.3 0.066 11.5 0.1 1.7 2 0 0 2 2 2 0 Infectious salmon anaemia virus haemagglutinin Hemerythrin PF01814.18 EEA05013.1 - 0.11 12.6 6.2 9.1 6.4 0.1 3.7 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain IncA PF04156.9 EEA05013.1 - 0.18 11.3 56.3 0.12 11.9 16.7 4.6 2 1 2 4 4 4 0 IncA protein Cytochrom_C_2 PF01322.15 EEA05013.1 - 4.3 7.9 10.8 0.19 12.2 1.0 3.2 4 0 0 4 4 4 0 Cytochrome C' Reo_sigmaC PF04582.7 EEA05013.1 - 4.7 6.2 15.2 1.2 8.2 2.7 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EEA05013.1 - 6.8 7.0 11.4 0.97 9.7 0.5 3.9 3 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EEA05013.1 - 8.8 6.1 15.2 2.8 7.7 0.6 3.7 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArfGap PF01412.13 EEA05014.1 - 6.3e-31 106.5 0.1 1.2e-30 105.6 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WIF PF02019.13 EEA05014.1 - 0.066 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 WIF domain DUF1841 PF08897.6 EEA05015.1 - 0.066 13.0 0.2 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Mg_trans_NIPA PF05653.9 EEA05016.1 - 2.3e-16 59.6 15.6 1.9e-09 36.8 1.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EEA05016.1 - 1.2 9.1 25.6 0.27 11.3 5.0 4.0 4 0 0 4 4 4 0 EamA-like transporter family Imm20 PF15568.1 EEA05017.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 20 B-block_TFIIIC PF04182.7 EEA05019.1 - 2.8e-27 94.3 0.3 9.9e-22 76.5 0.0 3.6 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.12 EEA05019.1 - 0.0018 17.7 0.2 0.062 12.8 0.0 3.3 3 0 0 3 3 3 1 TFIIE alpha subunit HTH_5 PF01022.15 EEA05019.1 - 0.0032 17.1 0.8 0.13 11.9 0.0 3.5 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family Ribosomal_L13 PF00572.13 EEA05021.1 - 5.5e-23 81.4 0.1 1.1e-22 80.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 TLD PF07534.11 EEA05022.1 - 2.4e-31 108.5 1.0 1.4e-14 54.2 0.0 2.3 1 1 0 2 2 2 2 TLD PCI PF01399.22 EEA05023.1 - 5.9e-09 36.1 0.1 2.1e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain CoA_binding PF02629.14 EEA05024.1 - 6.7e-22 77.8 2.3 1e-21 77.2 0.5 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EEA05024.1 - 1.9e-21 76.2 0.1 3.3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEA05024.1 - 5.8e-07 29.1 0.2 2.3e-06 27.2 0.2 2.0 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEA05024.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain Histone PF00125.19 EEA05025.1 - 5.9e-20 71.1 0.1 7.7e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA05025.1 - 0.00069 19.6 0.0 0.00098 19.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prefoldin PF02996.12 EEA05026.1 - 3.8e-19 68.4 0.2 4.8e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EEA05026.1 - 0.071 12.8 0.3 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit PRP1_N PF06424.7 EEA05028.1 - 6.9e-28 97.6 0.2 1.3e-27 96.7 0.2 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EEA05028.1 - 6e-20 69.9 7.9 0.026 15.1 0.1 10.0 6 3 4 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEA05028.1 - 5.2e-14 52.3 0.4 1.7e-06 28.2 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA05028.1 - 4.2e-13 48.7 3.3 0.0002 20.9 0.0 6.4 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 EEA05028.1 - 1.2e-07 30.9 0.4 2.7 7.9 0.0 6.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA05028.1 - 2.2e-07 31.3 0.0 5.2 7.8 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA05028.1 - 6.9e-07 29.1 0.1 0.82 9.6 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05028.1 - 3.2e-06 26.6 3.3 1.2 9.1 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA05028.1 - 5.7e-05 23.0 0.1 6.7 7.1 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EEA05028.1 - 6.1e-05 22.8 1.2 0.23 11.1 0.0 4.5 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EEA05028.1 - 0.00021 20.4 2.3 0.018 14.1 0.2 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA05028.1 - 0.0013 18.2 0.3 35 4.2 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.5 EEA05028.1 - 0.002 16.9 5.6 0.045 12.5 0.0 4.0 4 1 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 EEA05028.1 - 0.0048 16.5 0.0 5.9 6.9 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA05028.1 - 0.1 12.4 0.5 11 5.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ParA PF10609.4 EEA05030.1 - 4.9e-35 119.2 0.0 1.3e-34 117.9 0.0 1.8 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEA05030.1 - 3e-16 59.4 0.0 5.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 EEA05030.1 - 1.5e-15 56.8 0.0 3.6e-14 52.4 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function DUF59 DUF971 PF06155.7 EEA05030.1 - 4.5e-11 43.0 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) AAA_31 PF13614.1 EEA05030.1 - 7.7e-09 35.6 0.6 1.4e-07 31.6 0.0 3.1 4 0 0 4 4 4 1 AAA domain MipZ PF09140.6 EEA05030.1 - 3e-05 23.2 0.0 5.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EEA05030.1 - 0.00027 20.0 0.5 0.027 13.5 0.2 2.6 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EEA05030.1 - 0.012 14.8 0.3 0.036 13.2 0.1 1.7 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Peptidase_C39 PF03412.10 EEA05030.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family AAA_10 PF12846.2 EEA05030.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain YhjQ PF06564.7 EEA05030.1 - 0.16 11.2 0.0 0.77 9.0 0.0 1.9 2 0 0 2 2 2 0 YhjQ protein DUF258 PF03193.11 EEA05030.1 - 0.72 9.0 5.9 5.6 6.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 SNARE PF05739.14 EEA05032.1 - 8.7e-13 47.7 0.3 8.7e-13 47.7 0.2 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEA05032.1 - 0.034 14.3 9.7 0.46 10.6 6.8 2.4 1 1 0 1 1 1 0 Syntaxin DUF1850 PF08905.6 EEA05032.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) DUF1293 PF06950.6 EEA05032.1 - 0.11 12.3 0.1 0.43 10.4 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1293) RNA_polI_A14 PF08203.6 EEA05032.1 - 2 8.6 6.1 4.7 7.5 0.1 3.1 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 ATP-synt_F PF01990.12 EEA05034.1 - 5.6e-28 97.1 0.1 7.1e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF4252 PF14060.1 EEA05034.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) PP2C PF00481.16 EEA05035.1 - 8.8e-41 139.9 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C AFG1_ATPase PF03969.11 EEA05036.1 - 7.8e-64 215.7 0.1 1.5e-48 165.4 0.1 2.1 1 1 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 EEA05036.1 - 8.2e-08 32.1 1.2 1.4e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 Bacterial dnaA protein AAA PF00004.24 EEA05036.1 - 6.4e-06 26.3 0.2 3.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA05036.1 - 9.2e-06 25.8 3.6 0.0023 18.0 1.0 4.1 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EEA05036.1 - 0.0014 18.3 1.9 0.68 9.5 0.0 2.6 1 1 1 2 2 2 2 Archaeal ATPase AAA_14 PF13173.1 EEA05036.1 - 0.012 15.5 3.0 0.017 14.9 0.4 2.2 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEA05036.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEA05036.1 - 0.031 14.4 0.2 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 EEA05036.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_L32p PF01783.18 EEA05036.1 - 0.097 12.8 0.4 0.51 10.5 0.3 2.2 1 0 0 1 1 1 0 Ribosomal L32p protein family NACHT PF05729.7 EEA05036.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EEA05036.1 - 0.11 12.0 0.1 0.3 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain VCBS PF13517.1 EEA05037.1 - 6.3e-22 77.6 10.8 2.4e-06 27.8 0.9 6.4 5 1 1 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EEA05037.1 - 2.9e-12 45.9 17.5 0.037 13.7 0.2 6.9 7 0 0 7 7 7 6 FG-GAP repeat EF-hand_1 PF00036.27 EEA05037.1 - 0.69 9.3 4.2 54 3.4 0.0 4.0 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.1 EEA05037.1 - 3.7 7.0 8.8 15 5.1 0.0 3.6 3 0 0 3 3 3 0 EF hand Pkinase PF00069.20 EEA05038.1 - 2e-80 269.7 0.0 3e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05038.1 - 1.9e-41 141.8 0.0 3.2e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EEA05038.1 - 1.5e-28 95.9 10.1 1.4e-06 27.1 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA05038.1 - 7e-24 83.7 5.5 1.1e-11 44.6 0.7 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA05038.1 - 3.5e-22 76.7 8.8 1.6e-06 27.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEA05038.1 - 1.8e-21 74.0 5.4 6.6e-06 25.5 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EEA05038.1 - 6e-17 60.9 12.7 0.00079 18.9 0.3 4.9 3 1 2 5 5 5 4 EF-hand domain pair Kinase-like PF14531.1 EEA05038.1 - 1.2e-08 34.3 0.0 1.1e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.4 EEA05038.1 - 2.7e-07 30.6 1.6 0.0022 18.0 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEA05038.1 - 2.3e-06 27.2 7.2 0.0094 15.6 0.3 3.5 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand APH PF01636.18 EEA05038.1 - 0.0072 16.0 0.0 0.037 13.7 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA05038.1 - 0.016 14.2 0.1 0.039 12.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEA05038.1 - 0.02 14.2 1.1 0.049 12.9 0.2 1.9 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 EEA05038.1 - 0.024 13.9 0.1 0.062 12.6 0.1 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EF-hand_9 PF14658.1 EEA05038.1 - 0.036 13.9 0.2 0.35 10.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain LRR_4 PF12799.2 EEA05039.1 - 2.5e-17 62.0 38.7 5.2e-08 32.3 3.6 5.2 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA05039.1 - 6.1e-13 48.3 39.3 4e-07 29.6 1.1 5.9 4 2 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 EEA05039.1 - 2.7e-09 35.7 36.1 0.04 13.9 0.2 8.9 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_6 PF13516.1 EEA05039.1 - 5.8e-07 28.9 25.2 0.13 12.4 0.2 8.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 EEA05039.1 - 8.8e-06 25.1 19.1 1.3 9.5 0.2 8.0 6 0 0 6 6 6 2 Leucine rich repeat DUF155 PF02582.9 EEA05040.1 - 4.5e-42 143.9 0.0 7.3e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Glyco_transf_92 PF01697.22 EEA05041.1 - 3.5e-20 72.4 3.7 8.1e-19 67.9 2.5 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EEA05041.1 - 0.00093 19.4 0.0 0.0045 17.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 C2 PF00168.25 EEA05042.1 - 1.1e-07 31.6 0.0 1.2e-06 28.2 0.0 2.9 3 0 0 3 3 3 1 C2 domain Malic_M PF03949.10 EEA05044.1 - 1.7e-79 266.9 0.0 2.2e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEA05044.1 - 1.2e-59 200.9 0.0 1.8e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain WD40 PF00400.27 EEA05047.1 - 5.9e-26 89.3 16.1 2.3e-05 24.0 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA05047.1 - 2.2e-23 81.9 0.4 2.4e-22 78.6 0.2 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Imm8 PF15560.1 EEA05047.1 - 0.0014 18.2 0.2 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 Immunity protein 8 RNA_pol_Rpb1_5 PF04998.12 EEA05048.1 - 1.3e-81 273.9 0.1 6.9e-81 271.5 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEA05048.1 - 3.4e-56 189.7 0.0 1e-55 188.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEA05048.1 - 2.5e-31 108.5 0.2 8.7e-31 106.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EEA05048.1 - 1.9e-24 86.5 0.6 1.9e-24 86.5 0.4 4.2 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EEA05048.1 - 9.1e-17 60.7 0.3 5.5e-16 58.2 0.2 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_transf_5 PF08323.6 EEA05049.1 - 4.8e-57 193.2 0.0 7.5e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEA05049.1 - 1.4e-16 60.4 0.0 3e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA05049.1 - 6.3e-06 26.3 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEA05049.1 - 0.15 12.3 0.1 2.4 8.4 0.0 2.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 Choline_kinase PF01633.15 EEA05050.1 - 8.2e-42 143.1 0.4 1.4e-41 142.3 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEA05050.1 - 4.2e-07 29.9 0.0 1.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEA05050.1 - 0.008 15.3 0.3 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain YIF1 PF03878.10 EEA05051.1 - 1.2e-25 90.1 7.4 1.6e-25 89.6 5.1 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EEA05051.1 - 3.6 7.0 20.5 1.6 8.1 12.0 1.9 1 1 1 2 2 2 0 Yip1 domain RRM_1 PF00076.17 EEA05052.1 - 9e-39 130.9 0.0 3.7e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05052.1 - 2.5e-32 110.6 0.0 3.1e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05052.1 - 2e-17 62.7 0.0 5.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA05052.1 - 0.00061 19.5 0.2 0.4 10.4 0.1 2.9 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEA05052.1 - 0.013 15.1 0.0 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Laminin_G_1 PF00054.18 EEA05052.1 - 0.049 13.6 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain CSD PF00313.17 EEA05052.1 - 0.14 11.9 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Glycos_transf_2 PF00535.21 EEA05053.1 - 1.5e-25 89.8 0.0 3.2e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 EEA05053.1 - 2.8e-12 45.9 0.1 7e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.17 EEA05053.1 - 1.5e-11 44.4 0.9 2.6e-11 43.6 0.6 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 EEA05053.1 - 3.9e-10 39.9 0.0 6.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEA05053.1 - 1.2e-08 34.3 0.0 3.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA05053.1 - 0.039 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 WD40 PF00400.27 EEA05054.1 - 3.9e-23 80.4 6.7 3.6e-07 29.8 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EEA05054.1 - 0.0019 17.7 0.0 0.0047 16.4 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EEA05054.1 - 0.052 13.8 0.0 8.2 6.8 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.3 EEA05054.1 - 0.06 11.4 0.0 0.091 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TIP49 PF06068.8 EEA05055.1 - 6e-171 568.5 3.7 7.2e-171 568.2 2.5 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEA05055.1 - 1.6e-11 44.5 0.4 1e-07 32.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA05055.1 - 1.1e-08 34.3 2.6 5.4e-05 22.3 0.1 3.0 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA05055.1 - 7.7e-07 29.2 0.0 9.6e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EEA05055.1 - 1.2e-06 28.3 0.1 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA05055.1 - 2.4e-06 27.7 0.1 0.015 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.10 EEA05055.1 - 7.2e-06 25.0 0.1 1.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EEA05055.1 - 8.4e-05 21.8 0.9 0.019 14.1 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EEA05055.1 - 9.1e-05 23.2 0.5 0.00027 21.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EEA05055.1 - 0.00013 21.5 0.3 0.062 12.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EEA05055.1 - 0.00029 20.3 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA05055.1 - 0.00047 19.2 0.1 0.001 18.2 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EEA05055.1 - 0.00049 19.7 0.1 0.0012 18.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EEA05055.1 - 0.0007 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EEA05055.1 - 0.0015 18.2 0.7 0.048 13.2 0.0 2.7 3 1 0 3 3 2 1 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 EEA05055.1 - 0.0017 18.2 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA05055.1 - 0.0021 18.3 0.4 0.0063 16.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain KaiC PF06745.8 EEA05055.1 - 0.0021 17.1 0.1 0.0037 16.4 0.1 1.4 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.12 EEA05055.1 - 0.0046 15.8 0.1 0.0075 15.1 0.1 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PIF1 PF05970.9 EEA05055.1 - 0.0058 15.6 0.4 1.9 7.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase NACHT PF05729.7 EEA05055.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 EEA05055.1 - 0.008 15.6 0.1 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein GvpD PF07088.6 EEA05055.1 - 0.013 13.8 0.1 0.03 12.6 0.0 1.5 2 0 0 2 2 2 0 GvpD gas vesicle protein UPF0079 PF02367.12 EEA05055.1 - 0.014 14.9 0.1 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 EEA05055.1 - 0.025 14.0 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DNA_pol3_delta2 PF13177.1 EEA05055.1 - 0.027 14.1 0.1 0.089 12.4 0.0 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_30 PF13604.1 EEA05055.1 - 0.034 13.7 0.5 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EEA05055.1 - 0.034 14.1 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EEA05055.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase KTI12 PF08433.5 EEA05055.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 EEA05055.1 - 0.064 12.8 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EEA05055.1 - 0.07 13.0 0.7 0.63 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) FtsK_SpoIIIE PF01580.13 EEA05055.1 - 0.097 12.1 0.3 15 4.9 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 EEA05055.1 - 0.13 11.4 3.9 0.18 10.9 0.2 2.6 3 0 0 3 3 3 0 PhoH-like protein AAA_28 PF13521.1 EEA05055.1 - 0.13 12.2 0.2 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EEA05055.1 - 1.4 8.6 5.1 4.4 6.9 1.3 2.9 2 1 0 2 2 2 0 NTPase Thioredoxin PF00085.15 EEA05056.1 - 1.4e-14 53.6 0.9 2.8e-14 52.6 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA05056.1 - 0.00071 19.6 0.2 0.0015 18.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EEA05056.1 - 0.0074 15.9 0.2 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family MRL1 PF13003.2 EEA05056.1 - 0.0091 15.8 1.8 0.015 15.1 1.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1 Thioredoxin_7 PF13899.1 EEA05056.1 - 0.015 15.3 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA05056.1 - 0.065 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1201 PF06716.6 EEA05056.1 - 0.13 12.1 2.0 1 9.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) DUF629 PF04780.7 EEA05057.1 - 0.021 13.3 0.1 0.044 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) IMCp PF12314.3 EEA05058.1 - 3e-27 94.5 105.2 3.6e-14 52.6 18.4 5.6 1 1 3 4 4 4 2 Inner membrane complex protein Ank_2 PF12796.2 EEA05059.1 - 1.7e-30 105.2 1.3 2.1e-19 69.6 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA05059.1 - 1.4e-24 85.9 2.1 2.3e-10 40.7 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EEA05059.1 - 4e-23 80.0 2.6 1.8e-08 33.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EEA05059.1 - 1.7e-20 71.0 0.6 1.2e-06 28.1 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Bromodomain PF00439.20 EEA05059.1 - 2.6e-17 62.4 0.2 7e-17 61.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Ank_5 PF13857.1 EEA05059.1 - 3.8e-15 55.5 1.2 1.4e-10 41.0 0.3 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Asn_synthase PF00733.16 EEA05059.1 - 0.099 12.1 0.0 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 Asparagine synthase Ala_racemase_N PF01168.15 EEA05060.1 - 1e-32 113.5 0.0 1.2e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA-synt_1 PF00133.17 EEA05061.1 - 1.5e-38 132.2 0.0 5.5e-20 70.9 0.0 3.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEA05061.1 - 7.8e-21 74.1 4.9 8.4e-12 44.4 0.0 3.1 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEA05061.1 - 4.7e-12 45.9 1.0 4.7e-12 45.9 0.7 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEA05061.1 - 1e-09 37.9 0.1 8.2e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Mo-nitro_C PF06967.6 EEA05061.1 - 0.061 13.4 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Actin PF00022.14 EEA05062.1 - 4e-47 160.5 0.0 4.9e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA05062.1 - 0.094 11.2 0.1 1.1 7.7 0.0 2.2 2 1 0 2 2 2 0 MreB/Mbl protein DUF1279 PF06916.8 EEA05063.1 - 6.2e-15 55.2 0.2 1e-14 54.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2839 PF10999.3 EEA05063.1 - 0.13 12.2 1.1 0.43 10.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF326 PF03860.11 EEA05064.1 - 0.43 10.4 1.3 0.93 9.4 0.9 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-MYND PF01753.13 EEA05065.1 - 1.9e-07 30.8 7.4 3.9e-07 29.8 5.1 1.5 1 0 0 1 1 1 1 MYND finger BamHI PF02923.10 EEA05065.1 - 0.44 10.4 4.2 3.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Restriction endonuclease BamHI Beta-Casp PF10996.3 EEA05066.1 - 9.6e-11 41.7 0.0 3e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Fringe PF02434.11 EEA05067.1 - 4.4e-21 75.2 0.1 4.7e-19 68.5 0.0 3.0 2 1 0 2 2 2 1 Fringe-like MMS22L_N PF14910.1 EEA05067.1 - 0.012 13.8 0.0 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal ATP-synt_D PF01813.12 EEA05068.1 - 6.3e-64 215.1 0.8 7.4e-64 214.9 0.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D ATP_bind_3 PF01171.15 EEA05069.1 - 4e-14 52.5 0.0 7.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Integrase_Zn PF02022.14 EEA05069.1 - 0.065 12.6 1.0 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain Symplekin_C PF12295.3 EEA05070.1 - 1.1e-42 146.0 4.4 1.4e-42 145.6 0.1 3.2 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal HEAT_2 PF13646.1 EEA05070.1 - 0.018 15.3 0.0 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats tRNA_m1G_MT PF01746.16 EEA05071.1 - 3.1e-20 72.5 0.1 4e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GDPD PF03009.12 EEA05072.1 - 2.4e-27 96.0 0.0 1.4e-18 67.3 0.0 2.4 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EEA05072.1 - 0.012 15.7 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Proteasom_Rpn13 PF04683.8 EEA05073.1 - 7.6e-18 64.3 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Spo0A_C PF08769.6 EEA05073.1 - 0.04 13.8 0.0 1.9 8.4 0.0 2.2 1 1 1 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF1479 PF07350.7 EEA05073.1 - 0.098 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DUF4300 PF14133.1 EEA05074.1 - 0.033 13.4 0.1 0.048 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) Abhydrolase_5 PF12695.2 EEA05075.1 - 1.1e-07 31.6 0.0 2.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA05075.1 - 1.4e-05 25.0 0.0 0.00011 22.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA05075.1 - 2.4e-05 23.9 0.1 0.00052 19.6 0.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA05075.1 - 0.00011 21.7 1.4 0.0052 16.2 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEA05075.1 - 0.00051 19.3 0.5 0.0071 15.5 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 EEA05075.1 - 0.012 15.0 0.0 0.063 12.7 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1749 PF08538.5 EEA05076.1 - 0.048 12.5 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) zf-C3HC4_2 PF13923.1 EEA05077.1 - 6.4e-10 38.8 8.9 1.6e-07 31.2 4.6 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA05077.1 - 9.6e-09 34.7 11.1 9e-08 31.6 7.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA05077.1 - 3.3e-07 30.0 11.3 4.7e-06 26.3 7.7 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA05077.1 - 7.4e-07 28.7 8.5 7.2e-06 25.5 6.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA05077.1 - 2.2e-06 27.2 11.5 1.3e-05 24.8 4.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EEA05077.1 - 5e-05 22.7 6.1 7.5e-05 22.2 1.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEA05077.1 - 0.00034 20.6 6.3 0.00069 19.6 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EEA05077.1 - 0.018 14.8 13.5 0.022 14.5 3.5 2.8 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EEA05077.1 - 0.021 14.2 2.8 0.021 14.2 2.0 2.6 3 0 0 3 3 3 0 P-11 zinc finger zf-MIZ PF02891.15 EEA05077.1 - 0.056 12.9 9.1 2.1 7.9 4.8 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EEA05077.1 - 0.13 12.1 6.3 0.51 10.2 4.3 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEA05077.1 - 0.26 11.0 9.5 1.6 8.4 6.2 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-3CxxC PF13695.1 EEA05077.1 - 0.27 11.4 5.8 0.23 11.6 1.9 2.4 2 1 0 2 2 2 0 Zinc-binding domain zf-H2C2_2 PF13465.1 EEA05077.1 - 1.1 9.6 6.4 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DZR PF12773.2 EEA05077.1 - 1.2 8.9 6.1 5.1 7.0 2.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 EEA05077.1 - 3.2 7.9 7.7 2.8 8.1 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) CAP_C PF08603.6 EEA05078.1 - 9.7e-50 168.0 10.8 1.2e-49 167.7 7.5 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EEA05078.1 - 1.2e-07 31.1 13.2 2.6e-07 30.0 9.2 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C HlyD_3 PF13437.1 EEA05078.1 - 0.00031 21.0 0.5 0.001 19.4 0.1 1.9 2 0 0 2 2 2 1 HlyD family secretion protein TPR_11 PF13414.1 EEA05079.1 - 1.4e-12 47.0 1.1 7.9e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA05079.1 - 4.8e-06 25.9 4.9 0.11 12.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05079.1 - 1e-05 25.0 0.5 2.5 8.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA05079.1 - 0.0023 18.2 0.1 0.011 16.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA05079.1 - 0.0063 16.6 2.8 0.77 9.9 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEA05079.1 - 0.012 15.7 0.1 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EEA05079.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA05079.1 - 0.019 14.8 0.7 1.5 8.7 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat PA28_beta PF02252.13 EEA05079.1 - 0.042 13.3 2.1 0.07 12.5 0.2 2.1 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit TPR_16 PF13432.1 EEA05079.1 - 0.074 13.7 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rad51 PF08423.6 EEA05081.1 - 1.7e-127 423.6 0.1 2.2e-127 423.3 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA05081.1 - 2.3e-12 46.7 0.0 4.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EEA05081.1 - 4.5e-10 39.0 0.0 6.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEA05081.1 - 7.6e-07 28.4 0.3 2e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EEA05081.1 - 8.1e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF3853 PF12964.2 EEA05081.1 - 0.016 15.0 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) AAA_22 PF13401.1 EEA05081.1 - 0.051 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Paramecium_SA PF01508.11 EEA05081.1 - 0.31 11.2 4.4 0.52 10.5 0.5 2.4 2 0 0 2 2 2 0 Paramecium surface antigen domain PCI PF01399.22 EEA05082.1 - 0.00034 20.8 1.1 0.0021 18.3 0.1 2.9 2 0 0 2 2 2 1 PCI domain DUF4286 PF14114.1 EEA05085.1 - 0.73 10.1 7.1 0.66 10.2 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4286) Allexi_40kDa PF05549.6 EEA05085.1 - 1.2 8.3 11.0 0.27 10.4 1.0 2.7 1 1 2 3 3 3 0 Allexivirus 40kDa protein HMG_box PF00505.14 EEA05086.1 - 3.8e-15 55.8 3.9 4e-15 55.8 1.6 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA05086.1 - 1.1e-10 41.7 2.4 1.8e-10 41.0 1.7 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEA05086.1 - 0.1 12.3 0.5 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 ALMS_motif PF15309.1 EEA05086.1 - 0.19 11.5 2.3 0.29 10.9 1.6 1.2 1 0 0 1 1 1 0 ALMS motif GMC_oxred_C PF05199.8 EEA05087.1 - 1e-14 55.0 0.0 3.7e-12 46.7 0.0 2.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EEA05087.1 - 6.8e-10 38.5 0.1 1.6e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase CPSF_A PF03178.10 EEA05088.1 - 3.5e-78 262.9 3.0 3.7e-77 259.5 0.4 2.8 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 EEA05088.1 - 4.8e-55 186.6 0.6 9.1e-55 185.7 0.4 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term adh_short PF00106.20 EEA05089.1 - 6.7e-15 55.4 0.0 1.6e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA05089.1 - 0.00071 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA05089.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rad60-SLD PF11976.3 EEA05090.1 - 3.5e-22 77.8 0.0 4.4e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEA05090.1 - 1.6e-08 33.8 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.15 EEA05090.1 - 0.012 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 UBX domain Methyltransf_23 PF13489.1 EEA05091.1 - 1.2e-09 38.1 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA05091.1 - 4.2e-06 27.1 0.1 4.5e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA05091.1 - 1.3e-05 24.7 0.2 2.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA05091.1 - 6.7e-05 23.4 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA05091.1 - 0.0016 18.8 0.1 0.031 14.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA05091.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA05091.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase hGDE_N PF14699.1 EEA05091.1 - 0.065 13.0 0.4 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Kri1_C PF12936.2 EEA05092.1 - 9.3e-26 89.6 2.8 9.3e-26 89.6 1.9 4.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EEA05092.1 - 2.9e-16 59.5 17.6 2.9e-16 59.5 12.2 5.3 4 2 1 5 5 5 1 KRI1-like family ZZ PF00569.12 EEA05092.1 - 0.31 10.5 7.5 0.69 9.5 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF2215 PF10225.4 EEA05092.1 - 4.6 6.6 5.7 0.4 10.0 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) YceG PF02618.11 EEA05094.1 - 0.075 12.0 2.2 0.099 11.6 1.5 1.1 1 0 0 1 1 1 0 YceG-like family Fibrillarin PF01269.12 EEA05096.1 - 7.5e-110 365.2 0.0 9.1e-110 365.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EEA05096.1 - 0.00029 20.4 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EEA05096.1 - 0.066 12.7 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EEA05096.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase UCH PF00443.24 EEA05097.1 - 6.6e-48 163.1 1.6 6.6e-48 163.1 1.1 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA05097.1 - 4.7e-25 88.6 1.2 4.7e-25 88.6 0.8 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L30 PF00327.15 EEA05098.1 - 8.7e-19 66.8 1.5 8.7e-19 66.8 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EEA05098.1 - 2.2e-09 37.1 9.6 3.8e-09 36.4 6.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Decorin_bind PF02352.10 EEA05098.1 - 0.023 14.7 0.3 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 Decorin binding protein Ribosomal_S8 PF00410.14 EEA05099.1 - 2.3e-24 85.6 0.0 3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Nop14 PF04147.7 EEA05100.1 - 5.1e-55 186.8 30.7 1.3e-48 165.5 19.2 2.7 2 1 0 2 2 2 2 Nop14-like family SKIP_SNW PF02731.10 EEA05101.1 - 1.6e-54 183.6 1.4 1.6e-54 183.6 1.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Asp-B-Hydro_N PF05279.6 EEA05101.1 - 0.11 12.2 4.1 0.17 11.7 2.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2335 PF10097.4 EEA05101.1 - 4.1 7.1 13.5 4 7.1 0.0 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) DUF4149 PF13664.1 EEA05102.1 - 0.51 10.4 15.5 0.97 9.5 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) TFIIS_M PF07500.9 EEA05103.1 - 1.5e-29 102.3 1.4 9.9e-29 99.7 0.1 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EEA05103.1 - 1.2e-19 69.6 5.9 2e-19 68.9 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EEA05103.1 - 4.1e-10 39.0 1.2 8.4e-10 38.0 0.8 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EEA05103.1 - 0.072 12.7 2.4 0.19 11.4 1.7 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNL PF05180.7 EEA05103.1 - 0.15 11.7 1.2 0.33 10.6 0.8 1.6 1 0 0 1 1 1 0 DNL zinc finger zinc_ribbon_5 PF13719.1 EEA05103.1 - 0.38 10.3 3.7 3.2 7.4 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEA05103.1 - 0.8 9.4 3.6 5.9 6.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 EEA05105.1 - 0.002 17.9 1.0 0.011 15.5 0.2 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 EEA05105.1 - 0.017 14.9 8.7 0.053 13.3 6.0 1.9 1 0 0 1 1 1 0 Ring finger domain eIF-5_eIF-2B PF01873.12 EEA05106.1 - 1.5e-35 121.6 0.0 2.9e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EEA05106.1 - 0.01 16.1 0.2 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar ExbD PF02472.11 EEA05106.1 - 0.067 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR TF_Zn_Ribbon PF08271.7 EEA05106.1 - 0.14 11.5 0.2 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.1 EEA05106.1 - 0.3 10.8 1.7 8.9 6.1 0.2 2.3 1 1 1 2 2 2 0 Zinc-ribbon Elf1 PF05129.8 EEA05106.1 - 3.6 7.3 5.9 0.82 9.4 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Acyl_transf_3 PF01757.17 EEA05107.1 - 1.1e-22 80.3 27.8 1.1e-22 80.3 19.3 2.2 2 0 0 2 2 2 1 Acyltransferase family Jiv90 PF14901.1 EEA05108.1 - 0.31 11.0 1.4 6.2 6.8 0.0 2.5 2 1 1 3 3 3 0 Cleavage inducing molecular chaperone Rcd1 PF04078.8 EEA05109.1 - 3.2e-119 396.6 0.5 3.7e-119 396.4 0.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sec23_trunk PF04811.10 EEA05110.1 - 3.7e-58 196.7 0.0 6.8e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EEA05110.1 - 1.9e-17 63.5 0.0 4.8e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEA05110.1 - 7e-17 60.7 4.2 1.5e-16 59.6 2.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EEA05110.1 - 5.4e-10 38.6 0.1 1.6e-09 37.1 0.1 1.9 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EEA05110.1 - 5.2e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat GNT-I PF03071.10 EEA05110.1 - 0.2 10.1 0.3 0.61 8.5 0.1 1.8 2 1 0 2 2 2 0 GNT-I family L31 PF09784.4 EEA05111.1 - 0.083 12.9 0.9 3.5 7.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 PI3_PI4_kinase PF00454.22 EEA05113.1 - 2.7e-22 79.4 0.1 2.2e-21 76.4 0.1 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEA05113.1 - 0.00023 20.4 1.6 0.00054 19.1 1.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MSP1_C PF07462.6 EEA05115.1 - 0.0062 14.9 2.3 0.0074 14.7 1.6 1.1 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus IncA PF04156.9 EEA05115.1 - 0.01 15.4 8.0 0.011 15.3 5.6 1.1 1 0 0 1 1 1 0 IncA protein ALIX_LYPXL_bnd PF13949.1 EEA05115.1 - 0.011 14.7 5.8 0.013 14.5 4.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF816 PF05674.7 EEA05115.1 - 0.024 14.3 0.9 0.032 13.9 0.6 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) HXXSHH PF07586.6 EEA05115.1 - 0.032 13.1 2.6 0.037 12.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Baculo_PEP_C PF04513.7 EEA05115.1 - 0.034 13.9 0.3 0.046 13.5 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 EEA05115.1 - 0.043 12.9 5.3 0.052 12.6 3.7 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Exonuc_VII_L PF02601.10 EEA05115.1 - 0.46 9.6 6.1 0.55 9.3 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.17 EEA05115.1 - 1.2 9.1 6.0 8.7 6.4 1.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EEA05115.1 - 1.9 7.9 7.4 3 7.3 0.8 2.0 1 1 1 2 2 2 0 GrpE DUF4140 PF13600.1 EEA05115.1 - 5.3 7.5 7.1 23 5.4 0.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.27 EEA05117.1 - 2.9e-27 93.5 15.7 4.2e-05 23.2 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EEA05117.1 - 3.4e-23 81.4 11.0 3.4e-23 81.4 7.6 1.6 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 EEA05117.1 - 0.00034 20.3 0.1 1.1 9.0 0.0 3.6 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region CCDC155 PF14662.1 EEA05118.1 - 0.00017 21.2 36.6 0.00017 21.2 25.3 3.1 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 HALZ PF02183.13 EEA05118.1 - 0.001 18.7 1.7 0.001 18.7 1.1 5.8 4 2 1 5 5 5 2 Homeobox associated leucine zipper DUF972 PF06156.8 EEA05118.1 - 0.0036 17.6 44.6 0.02 15.2 9.1 5.1 2 2 2 4 4 4 3 Protein of unknown function (DUF972) Prp19 PF08606.6 EEA05118.1 - 0.026 14.2 0.6 0.026 14.2 0.4 3.8 4 0 0 4 4 4 0 Prp19/Pso4-like DUF4140 PF13600.1 EEA05118.1 - 0.028 14.8 0.5 0.028 14.8 0.3 4.4 3 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 EEA05118.1 - 1.5 8.8 40.3 0.098 12.6 0.3 5.5 4 2 2 6 6 6 0 bZIP transcription factor MxiH PF09392.5 EEA05118.1 - 2.4 8.7 13.4 3.5 8.2 0.6 3.1 3 0 0 3 3 2 0 Type III secretion needle MxiH like UPF0184 PF03670.8 EEA05118.1 - 2.5 8.3 17.1 2.7 8.2 1.3 4.7 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0184) Reo_sigmaC PF04582.7 EEA05118.1 - 3.3 6.8 16.7 0.77 8.8 1.2 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF2205 PF10224.4 EEA05118.1 - 3.3 7.3 28.6 6.7 6.3 0.0 5.2 2 1 3 5 5 5 0 Predicted coiled-coil protein (DUF2205) Myosin_tail_1 PF01576.14 EEA05118.1 - 7 4.2 43.1 1.6 6.3 0.1 2.5 2 1 0 2 2 2 0 Myosin tail CYTL1 PF15153.1 EEA05119.1 - 0.055 13.1 1.3 0.19 11.4 0.1 2.3 1 1 1 2 2 2 0 Cytokine-like protein 1 Unstab_antitox PF09720.5 EEA05119.1 - 0.91 9.2 5.9 2.9 7.6 0.3 3.3 3 0 0 3 3 3 0 Putative addiction module component DUF2053 PF09767.4 EEA05120.1 - 9.9e-08 32.1 8.3 9.9e-08 32.1 5.8 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) Ndc80_HEC PF03801.8 EEA05121.1 - 0.36 10.2 7.1 2.5 7.5 0.4 2.8 3 0 0 3 3 3 0 HEC/Ndc80p family HBS1_N PF08938.5 EEA05122.1 - 0.084 13.0 7.6 0.68 10.1 0.8 3.9 3 1 0 3 3 3 0 HBS1 N-terminus SlyX PF04102.7 EEA05122.1 - 7.8 6.9 17.5 3.8 7.9 1.5 4.3 3 1 1 4 4 4 0 SlyX zf-DBF PF07535.7 EEA05124.1 - 0.09 12.4 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 DBF zinc finger Terminase_5 PF06056.7 EEA05124.1 - 0.17 11.4 0.0 0.48 10.0 0.0 1.7 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) NUDIX PF00293.23 EEA05125.1 - 6.1e-10 38.8 0.0 8.8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SNF2_N PF00176.18 EEA05126.1 - 1.1e-52 178.7 0.0 2.8e-52 177.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.24 EEA05126.1 - 1.6e-21 75.7 67.9 6e-11 41.8 4.2 6.7 6 0 0 6 6 6 5 PHD-finger Helicase_C PF00271.26 EEA05126.1 - 5.5e-10 38.9 0.0 2.8e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD_2 PF13831.1 EEA05126.1 - 0.00011 21.4 0.8 0.00011 21.4 0.6 7.5 8 0 0 8 8 8 2 PHD-finger ELO PF01151.13 EEA05127.1 - 4.2e-58 196.6 32.5 5.4e-58 196.2 22.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 EEA05128.1 - 0.0005 19.8 2.0 7.4 6.6 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat CactinC_cactus PF09732.4 EEA05128.1 - 0.019 14.5 0.8 2.5 7.6 0.4 2.6 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein DNA_pol_delta_4 PF04081.8 EEA05129.1 - 6.9e-07 29.5 0.0 7.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Hint PF01079.15 EEA05131.1 - 0.019 14.1 0.6 0.51 9.5 0.0 2.3 1 1 1 2 2 2 0 Hint module Brix PF04427.13 EEA05132.1 - 1.1e-22 80.6 0.0 2.4e-22 79.5 0.0 1.4 1 1 0 1 1 1 1 Brix domain Pkinase PF00069.20 EEA05134.1 - 8.6e-14 51.2 0.7 1.2e-13 50.8 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05134.1 - 6.1e-10 38.6 0.2 8.6e-10 38.1 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA05134.1 - 4.3e-09 35.7 0.0 5.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEA05134.1 - 2.4e-08 33.5 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EEA05134.1 - 9.6e-07 28.7 0.0 0.0019 17.9 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EEA05134.1 - 0.0029 16.8 1.1 0.0045 16.2 0.7 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1679 PF07914.6 EEA05134.1 - 0.004 15.8 0.3 0.011 14.4 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEA05134.1 - 0.012 14.7 1.0 0.033 13.3 0.3 1.8 1 1 1 2 2 2 0 Ecdysteroid kinase Choline_kinase PF01633.15 EEA05134.1 - 0.014 15.0 1.3 2.1 7.8 0.5 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase tRNA-synt_2b PF00587.20 EEA05136.1 - 1.2e-36 125.9 0.0 1.9e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEA05136.1 - 3.3e-15 56.0 7.8 3.3e-15 56.0 5.4 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TRAM_LAG1_CLN8 PF03798.11 EEA05137.1 - 3.4e-18 65.9 26.4 3.4e-18 65.9 18.3 1.7 2 0 0 2 2 2 1 TLC domain ARL6IP6 PF15062.1 EEA05137.1 - 0.08 12.8 1.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Herpes_LMP1 PF05297.6 EEA05137.1 - 6 5.6 15.8 13 4.5 11.0 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Adaptin_N PF01602.15 EEA05138.1 - 5.7e-89 298.8 9.5 2e-87 293.7 6.6 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EEA05138.1 - 7.1e-21 74.6 2.1 7.1e-21 74.6 1.5 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EEA05138.1 - 0.15 12.3 0.0 14 6.0 0.0 3.9 2 2 0 2 2 2 0 HEAT repeats DEAD PF00270.24 EEA05139.1 - 1.5e-18 66.9 0.0 8.6e-18 64.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA05139.1 - 3.2e-13 49.3 0.1 1.8e-12 46.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EEA05139.1 - 0.00049 20.6 1.7 0.004 17.6 1.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) GCFC PF07842.7 EEA05140.1 - 3.5e-06 26.5 1.7 1.6e-05 24.4 0.6 2.1 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein DUF3216 PF11505.3 EEA05140.1 - 0.095 12.5 2.5 0.48 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) DCP1 PF06058.8 EEA05141.1 - 4.2e-32 110.7 0.9 9.8e-32 109.5 0.6 1.7 1 0 0 1 1 1 1 Dcp1-like decapping family zf-C3HC4_2 PF13923.1 EEA05142.1 - 0.12 12.4 4.3 0.2 11.6 0.7 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA05142.1 - 0.25 11.1 3.8 0.27 11.0 0.9 2.4 2 1 0 2 2 2 0 Ring finger domain PH PF00169.24 EEA05143.1 - 0.00044 20.4 0.7 0.00044 20.4 0.5 2.1 3 0 0 3 3 3 1 PH domain EF-hand_7 PF13499.1 EEA05144.1 - 1.1e-15 57.4 6.9 4e-10 39.6 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA05144.1 - 2.6e-13 49.3 3.1 3.2e-08 33.0 0.0 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EEA05144.1 - 3.8e-13 47.7 5.0 0.00043 19.3 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEA05144.1 - 3.6e-12 45.0 7.4 0.00053 19.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA05144.1 - 1.6e-05 23.9 0.5 0.029 13.7 0.0 3.8 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.5 EEA05144.1 - 0.028 14.3 0.0 0.092 12.7 0.0 1.9 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 EEA05144.1 - 1.3 8.7 3.3 20 4.9 0.4 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand dDENN PF03455.14 EEA05145.1 - 0.056 13.5 2.5 2.5 8.2 0.3 2.3 2 0 0 2 2 2 0 dDENN domain Ran_BP1 PF00638.13 EEA05147.1 - 1.7e-38 131.4 2.9 1.7e-38 131.4 2.0 1.5 2 0 0 2 2 2 1 RanBP1 domain Ribosomal_L35p PF01632.14 EEA05147.1 - 0.089 12.7 1.9 0.17 11.8 1.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 WH1 PF00568.18 EEA05147.1 - 0.17 11.5 4.3 0.9 9.2 3.0 2.2 1 1 0 1 1 1 0 WH1 domain Abhydrolase_6 PF12697.2 EEA05148.1 - 1.2e-23 84.1 0.0 2.5e-23 83.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA05148.1 - 2.2e-14 53.4 0.0 3.5e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA05148.1 - 1e-12 48.0 0.0 4.2e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA05148.1 - 1.5e-06 27.9 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EEA05148.1 - 0.0012 18.2 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EEA05148.1 - 0.0071 15.8 0.0 0.0096 15.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EEA05148.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.9 EEA05148.1 - 0.018 13.5 0.0 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2305 PF10230.4 EEA05148.1 - 0.033 13.5 0.1 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EEA05148.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mpv17_PMP22 PF04117.7 EEA05149.1 - 6.4e-17 60.9 2.6 1.4e-16 59.8 1.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-C3HC4_3 PF13920.1 EEA05150.1 - 8.6e-08 31.7 13.3 3e-07 30.0 9.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05150.1 - 0.0068 16.4 16.0 0.0068 16.4 11.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA05152.1 - 1e-06 28.2 16.3 2.2e-06 27.2 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05152.1 - 0.02 14.9 16.9 0.051 13.6 11.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA05152.1 - 0.23 11.1 16.5 0.65 9.7 11.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CWC25 PF12542.3 EEA05154.1 - 1.7e-07 31.5 0.5 1.4e-06 28.6 0.0 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing factor Ins_P5_2-kin PF06090.7 EEA05155.1 - 2.6e-07 29.9 0.0 6.9e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Peptidase_U4 PF03419.8 EEA05157.1 - 0.066 12.2 13.8 0.09 11.8 9.6 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA zf-U1 PF06220.7 EEA05158.1 - 2.5e-17 62.1 1.8 2.5e-17 62.1 1.2 2.1 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EEA05158.1 - 0.0096 16.0 10.9 0.02 15.0 3.5 3.1 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA05158.1 - 5.8 6.7 9.4 9.7 6.0 0.5 2.4 2 0 0 2 2 2 0 BED zinc finger Metallophos PF00149.23 EEA05159.1 - 7.9e-36 123.3 2.5 1.1e-35 122.8 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Calici_PP_N PF08405.6 EEA05159.1 - 0.021 13.7 0.1 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal IMCp PF12314.3 EEA05160.1 - 1e-18 67.2 135.7 5.3e-13 48.9 25.7 6.5 1 1 4 5 5 5 4 Inner membrane complex protein Helicase_C PF00271.26 EEA05161.1 - 3.8e-13 49.0 0.0 1.3e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEA05161.1 - 7.1e-10 38.7 0.1 2.7e-09 36.8 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA05161.1 - 4.3e-08 33.0 0.0 4.3e-08 33.0 0.0 3.1 4 0 0 4 4 4 1 Helicase associated domain (HA2) DEAD PF00270.24 EEA05161.1 - 5.1e-06 26.0 0.6 4.4e-05 23.0 0.3 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA05161.1 - 7.1e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA05161.1 - 0.0055 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EEA05161.1 - 0.007 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEA05161.1 - 0.062 12.8 0.1 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain EF-hand_1 PF00036.27 EEA05163.1 - 1.4e-05 24.0 0.8 0.0013 17.9 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EEA05163.1 - 2.1e-05 24.5 1.7 5.6e-05 23.1 1.0 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA05163.1 - 8.1e-05 22.1 1.6 0.00047 19.8 0.1 2.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 EEA05163.1 - 0.008 15.7 0.4 12 5.6 0.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair Rifin_STEVOR PF02009.11 EEA05165.1 - 0.081 12.5 3.0 0.12 12.0 2.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family Oxidored_q3 PF00499.15 EEA05165.1 - 0.21 11.3 9.4 0.62 9.8 6.5 2.0 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4064 PF13273.1 EEA05165.1 - 2.6 8.1 9.4 0.11 12.6 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Macoilin PF09726.4 EEA05165.1 - 3 6.0 11.1 3.4 5.8 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 EEA05168.1 - 3.5e-06 26.9 7.3 4.5e-06 26.6 5.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EEA05168.1 - 5.7e-06 25.9 5.2 6.6e-06 25.7 3.6 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EEA05168.1 - 0.00013 21.9 3.7 0.00017 21.5 2.6 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 EEA05168.1 - 0.00098 16.5 3.6 0.0011 16.3 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ALIX_LYPXL_bnd PF13949.1 EEA05168.1 - 0.0034 16.3 1.6 0.004 16.1 1.1 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CENP-Q PF13094.1 EEA05168.1 - 0.0043 17.1 4.1 0.005 16.8 2.9 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.13 EEA05168.1 - 0.0048 16.5 5.1 0.0099 15.5 2.0 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper Cast PF10174.4 EEA05168.1 - 0.0052 14.9 4.1 0.0061 14.6 2.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone TMCO5 PF14992.1 EEA05168.1 - 0.0054 15.9 5.4 0.0056 15.8 3.8 1.0 1 0 0 1 1 1 1 TMCO5 family ThylakoidFormat PF11264.3 EEA05168.1 - 0.0068 16.0 2.1 0.0093 15.6 1.5 1.2 1 0 0 1 1 1 1 Thylakoid formation protein Spc7 PF08317.6 EEA05168.1 - 0.011 14.3 6.3 0.013 14.2 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EEA05168.1 - 0.012 14.6 6.3 0.013 14.5 4.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EEA05168.1 - 0.015 13.8 5.0 0.016 13.7 3.5 1.0 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EEA05168.1 - 0.015 14.8 6.8 0.019 14.5 4.7 1.1 1 0 0 1 1 1 0 IncA protein Serine_rich PF08824.5 EEA05168.1 - 0.015 14.9 2.1 0.023 14.4 1.1 1.4 1 1 0 1 1 1 0 Serine rich protein interaction domain Mnd1 PF03962.10 EEA05168.1 - 0.016 14.8 3.3 0.019 14.6 2.3 1.1 1 0 0 1 1 1 0 Mnd1 family Prominin PF05478.6 EEA05168.1 - 0.023 12.2 3.5 0.032 11.7 2.4 1.2 1 0 0 1 1 1 0 Prominin TMPIT PF07851.8 EEA05168.1 - 0.024 13.6 3.3 0.029 13.4 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0158 PF03682.8 EEA05168.1 - 0.025 14.2 1.7 0.029 14.0 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) V_ATPase_I PF01496.14 EEA05168.1 - 0.025 12.4 3.8 0.026 12.4 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 EEA05168.1 - 0.026 14.3 9.4 0.46 10.2 1.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit ENTH PF01417.15 EEA05168.1 - 0.026 14.3 1.1 0.03 14.1 0.7 1.2 1 0 0 1 1 1 0 ENTH domain DUF1664 PF07889.7 EEA05168.1 - 0.026 14.3 2.2 0.036 13.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EEA05168.1 - 0.028 14.2 8.0 0.048 13.4 5.6 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.4 EEA05168.1 - 0.029 14.2 5.6 0.034 13.9 3.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Mt_ATP-synt_B PF05405.9 EEA05168.1 - 0.03 13.8 2.5 0.034 13.6 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2347 PF09804.4 EEA05168.1 - 0.03 13.5 1.0 0.034 13.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) IFT57 PF10498.4 EEA05168.1 - 0.03 13.0 3.9 0.034 12.9 2.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Rootletin PF15035.1 EEA05168.1 - 0.036 14.0 4.3 0.043 13.7 3.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.2 EEA05168.1 - 0.038 13.8 7.5 0.045 13.6 5.2 1.1 1 0 0 1 1 1 0 Tropomyosin like Striatin PF08232.7 EEA05168.1 - 0.04 14.2 1.6 0.05 13.9 1.1 1.2 1 0 0 1 1 1 0 Striatin family Reo_sigmaC PF04582.7 EEA05168.1 - 0.042 13.0 0.3 0.05 12.7 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PA28_beta PF02252.13 EEA05168.1 - 0.043 13.2 0.4 4.3 6.7 0.0 2.1 1 1 1 2 2 2 0 Proteasome activator pa28 beta subunit Spectrin PF00435.16 EEA05168.1 - 0.047 13.9 3.6 0.34 11.2 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF2051 PF09738.4 EEA05168.1 - 0.05 12.8 6.4 0.057 12.6 4.4 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) SYCE1 PF15233.1 EEA05168.1 - 0.052 13.4 3.7 0.062 13.2 2.6 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Fib_alpha PF08702.5 EEA05168.1 - 0.056 13.5 7.5 0.083 13.0 5.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.1 EEA05168.1 - 0.062 13.1 2.3 0.077 12.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) RA PF00788.18 EEA05168.1 - 0.074 13.5 0.3 0.18 12.2 0.2 1.8 1 1 0 1 1 1 0 Ras association (RalGDS/AF-6) domain MIS13 PF08202.6 EEA05168.1 - 0.077 12.0 4.3 0.081 11.9 3.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF4559 PF15112.1 EEA05168.1 - 0.079 12.1 5.0 0.088 11.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF948 PF06103.6 EEA05168.1 - 0.081 12.8 2.1 0.11 12.3 1.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.9 EEA05168.1 - 0.081 12.8 1.9 0.1 12.5 1.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EEA05168.1 - 0.082 11.8 7.4 0.17 10.7 5.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin_2 PF14523.1 EEA05168.1 - 0.084 12.9 7.0 0.14 12.2 4.8 1.4 1 1 0 1 1 1 0 Syntaxin-like protein DUF964 PF06133.6 EEA05168.1 - 0.087 12.8 3.5 0.13 12.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DASH_Dad2 PF08654.5 EEA05168.1 - 0.089 12.7 4.0 0.25 11.3 0.1 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 UPF0242 PF06785.6 EEA05168.1 - 0.091 11.4 4.1 0.11 11.2 2.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) AbiH PF14253.1 EEA05168.1 - 0.093 12.3 3.4 0.11 12.1 2.3 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH YafO_toxin PF13957.1 EEA05168.1 - 0.099 12.4 0.4 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system DUF4527 PF15030.1 EEA05168.1 - 0.1 11.9 1.3 0.1 11.8 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF4473 PF14747.1 EEA05168.1 - 0.11 12.7 0.2 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) Bacillus_HBL PF05791.6 EEA05168.1 - 0.12 11.7 5.7 0.17 11.2 4.0 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.7 EEA05168.1 - 0.12 12.1 2.7 0.17 11.6 1.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EEA05168.1 - 0.12 12.6 5.8 0.34 11.2 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FliD_N PF02465.13 EEA05168.1 - 0.13 12.5 4.0 4.7 7.6 0.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus K-box PF01486.12 EEA05168.1 - 0.14 11.9 7.0 2.5 7.9 0.6 2.3 1 1 0 2 2 2 0 K-box region PilJ PF13675.1 EEA05168.1 - 0.17 12.1 1.4 0.3 11.4 1.0 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Spc34 PF08657.5 EEA05168.1 - 0.18 11.4 7.7 0.58 9.7 5.3 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 Prefoldin PF02996.12 EEA05168.1 - 0.19 11.4 5.8 0.98 9.0 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit DASH_Dam1 PF08653.5 EEA05168.1 - 0.24 11.2 1.3 2.9 7.7 0.1 2.5 1 1 1 2 2 2 0 DASH complex subunit Dam1 Tektin PF03148.9 EEA05168.1 - 0.25 9.8 8.5 0.27 9.7 4.6 1.7 1 1 1 2 2 2 0 Tektin family DUF342 PF03961.8 EEA05168.1 - 0.31 9.4 3.5 0.35 9.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 EEA05168.1 - 0.32 11.1 4.0 0.42 10.7 2.8 1.3 1 0 0 1 1 1 0 Syntaxin Syntaxin-6_N PF09177.6 EEA05168.1 - 0.33 11.3 3.5 0.56 10.6 2.4 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DLD PF14878.1 EEA05168.1 - 0.35 11.0 3.5 0.57 10.3 0.3 2.1 1 1 1 2 2 2 0 Death-like domain of SPT6 DUF904 PF06005.7 EEA05168.1 - 0.4 10.9 8.7 0.093 13.0 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) COG2 PF06148.6 EEA05168.1 - 0.5 10.2 5.1 4 7.3 2.1 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.1 EEA05168.1 - 0.53 9.9 6.0 0.64 9.6 4.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.3 EEA05168.1 - 0.69 9.7 6.9 2 8.2 4.8 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Bap31 PF05529.7 EEA05168.1 - 0.69 9.3 4.9 0.88 8.9 3.4 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like UBN2_3 PF14244.1 EEA05168.1 - 0.71 9.4 4.0 1.3 8.5 2.8 1.5 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type CorA PF01544.13 EEA05168.1 - 0.73 8.8 4.9 0.88 8.5 3.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 EEA05168.1 - 0.94 9.8 7.2 1.8 8.9 4.8 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Baculo_PEP_C PF04513.7 EEA05168.1 - 1.3 8.8 6.4 2.4 7.9 4.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 EEA05168.1 - 1.4 8.4 10.0 3 7.4 1.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF2205 PF10224.4 EEA05168.1 - 3.4 7.2 8.4 9.5 5.8 4.1 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 EEA05168.1 - 9.4 6.2 8.2 21 5.1 2.7 2.3 1 1 1 2 2 2 0 bZIP transcription factor Ribosomal_L7Ae PF01248.21 EEA05170.1 - 7.7e-19 67.0 0.1 1.2e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_C48 PF02902.14 EEA05171.1 - 3.7e-19 69.1 7.2 5.2e-19 68.7 5.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vhr1 PF04001.8 EEA05171.1 - 0.026 14.4 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 UPF0086 PF01868.11 EEA05174.1 - 3.9e-20 71.2 0.0 8.3e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 ArsC PF03960.10 EEA05174.1 - 0.14 12.2 4.1 0.13 12.3 0.6 2.2 2 1 0 2 2 2 0 ArsC family FF PF01846.14 EEA05175.1 - 0.069 13.1 0.8 20 5.2 0.0 3.0 2 0 0 2 2 2 0 FF domain UPF0118 PF01594.11 EEA05176.1 - 0.046 12.6 6.5 0.31 9.9 4.8 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF20 Fimbrial PF00419.15 EEA05176.1 - 0.082 13.1 1.3 0.096 12.9 0.9 1.1 1 0 0 1 1 1 0 Fimbrial protein DUF2367 PF10164.4 EEA05176.1 - 1.3 8.9 9.7 2.5 8.0 6.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) ATP12 PF07542.6 EEA05177.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein Ribosomal_L29 PF00831.18 EEA05178.1 - 9.2e-19 66.8 3.6 1.9e-18 65.9 2.5 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EEA05178.1 - 0.054 13.7 0.6 0.068 13.4 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 SWIB PF02201.13 EEA05179.1 - 2e-07 30.5 0.1 6.2e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain tify PF06200.9 EEA05179.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 tify domain Arf PF00025.16 EEA05181.1 - 5.7e-79 263.3 0.1 6.5e-79 263.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA05181.1 - 6.8e-14 51.4 0.0 8.1e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEA05181.1 - 4e-13 49.0 0.0 4.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA05181.1 - 6.5e-11 41.5 0.5 1.1e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA05181.1 - 7.3e-11 41.6 0.0 8.8e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA05181.1 - 1.1e-09 38.7 0.0 1.6e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA05181.1 - 4.5e-06 26.6 0.0 6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA05181.1 - 0.0009 18.7 0.1 0.0044 16.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA05181.1 - 0.0065 15.5 0.0 0.0084 15.2 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEA05181.1 - 0.011 15.6 0.5 0.082 12.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain Flavoprotein PF02441.14 EEA05182.1 - 7.2e-43 145.3 0.5 8.9e-43 145.0 0.4 1.1 1 0 0 1 1 1 1 Flavoprotein FtsJ PF01728.14 EEA05184.1 - 2.9e-64 216.3 0.0 3.4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rad60-SLD PF11976.3 EEA05185.1 - 0.00012 21.7 0.3 0.00012 21.7 0.2 2.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like FAM176 PF14851.1 EEA05185.1 - 0.078 12.6 0.7 0.12 12.0 0.5 1.2 1 0 0 1 1 1 0 FAM176 family Rad10 PF03834.9 EEA05186.1 - 0.003 17.2 1.0 0.0075 15.9 0.7 1.7 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Pkinase PF00069.20 EEA05187.1 - 5.6e-81 271.4 0.8 1.1e-80 270.5 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05187.1 - 1.9e-42 145.1 0.0 3.5e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EEA05187.1 - 1.3e-25 86.6 11.1 9.6e-08 30.8 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA05187.1 - 1.6e-22 79.3 15.1 5e-13 48.9 1.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EEA05187.1 - 5.6e-20 70.6 9.8 0.00011 21.7 0.4 4.9 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EEA05187.1 - 2.1e-19 67.8 9.5 4.1e-06 25.8 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEA05187.1 - 3.1e-17 60.8 11.5 1.4e-05 24.6 0.3 5.5 3 1 2 5 5 5 4 EF-hand domain Kdo PF06293.9 EEA05187.1 - 5.1e-06 25.6 0.0 1.4e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 EEA05187.1 - 1e-05 25.2 5.8 0.23 11.2 0.4 4.2 1 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 EEA05187.1 - 1.1e-05 24.6 0.0 0.00056 18.9 0.0 2.4 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.4 EEA05187.1 - 0.00053 19.9 2.4 0.51 10.3 0.2 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region YrbL-PhoP_reg PF10707.4 EEA05187.1 - 0.0011 18.3 0.7 0.0026 17.1 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EEA05187.1 - 0.004 16.9 0.0 0.015 15.0 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA05187.1 - 0.096 12.2 2.7 0.085 12.4 0.4 2.0 2 1 1 3 3 3 0 Choline/ethanolamine kinase DUF3274 PF11678.3 EEA05188.1 - 0.0003 20.1 0.8 0.00038 19.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) DnaJ PF00226.26 EEA05189.1 - 1.4e-13 50.3 2.1 7.3e-13 48.0 1.4 2.1 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EEA05189.1 - 1.3e-08 34.2 1.1 2.2e-08 33.4 0.8 1.4 1 0 0 1 1 1 1 CSL zinc finger Muted PF14942.1 EEA05190.1 - 0.028 14.3 2.8 0.028 14.3 1.9 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Rootletin PF15035.1 EEA05190.1 - 0.061 13.3 9.6 0.32 10.9 6.6 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 EEA05190.1 - 0.095 10.5 3.0 0.11 10.3 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 EEA05190.1 - 0.19 11.7 4.4 0.15 12.0 1.5 1.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil KOG2701 PF09762.4 EEA05190.1 - 0.74 9.8 4.5 0.43 10.6 1.6 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) TSC22 PF01166.13 EEA05190.1 - 0.8 9.7 5.5 3.7 7.5 0.2 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family AATF-Che1 PF13339.1 EEA05190.1 - 1.6 8.8 6.2 5.7 7.1 0.5 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Tup_N PF08581.5 EEA05190.1 - 5.6 7.2 12.5 2.1 8.5 3.5 3.3 2 1 1 3 3 3 0 Tup N-terminal DUF1032 PF06278.6 EEA05191.1 - 4.8e-26 91.3 9.2 9.7e-13 47.4 4.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1032) RCR PF12273.3 EEA05192.1 - 0.03 14.8 2.5 0.034 14.6 0.3 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1475 PF07343.6 EEA05192.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) FA_desaturase PF00487.19 EEA05192.1 - 0.87 8.9 3.4 0.63 9.4 0.5 1.8 1 1 0 2 2 2 0 Fatty acid desaturase DUF4117 PF13491.1 EEA05193.1 - 0.013 14.9 0.3 0.028 13.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) Renin_r PF07850.9 EEA05193.1 - 0.028 14.7 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Renin receptor-like protein DUF4064 PF13273.1 EEA05193.1 - 0.084 12.9 0.6 0.29 11.2 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ca_hom_mod PF14798.1 EEA05193.1 - 0.094 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator LAP1C PF05609.7 EEA05193.1 - 0.14 10.7 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Rhomboid PF01694.17 EEA05194.1 - 1.7e-28 99.4 13.2 1.7e-28 99.4 9.2 1.9 3 0 0 3 3 3 1 Rhomboid family DER1 PF04511.10 EEA05194.1 - 5.3e-06 26.0 3.3 8.7e-06 25.3 2.3 1.3 1 0 0 1 1 1 1 Der1-like family DUF4389 PF14333.1 EEA05194.1 - 0.099 12.3 0.1 0.099 12.3 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4389) GWT1 PF06423.7 EEA05194.1 - 0.32 11.0 4.0 0.98 9.5 0.4 2.5 2 1 0 2 2 2 0 GWT1 Aminotran_5 PF00266.14 EEA05197.1 - 2.5e-26 92.3 0.0 1.8e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-V ATP_bind_3 PF01171.15 EEA05197.1 - 1.1e-15 57.6 0.0 2.5e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 PP-loop family TPR_12 PF13424.1 EEA05198.1 - 7.4e-06 25.8 0.0 0.00078 19.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05198.1 - 0.00092 18.9 0.0 1.5 8.9 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA05198.1 - 0.0074 15.9 0.9 4.7 6.9 0.2 3.3 2 1 0 2 2 2 2 TPR repeat zf-Tim10_DDP PF02953.10 EEA05199.1 - 8.7e-17 60.1 0.0 1e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps39_2 PF10367.4 EEA05200.1 - 2.5e-19 69.4 2.5 8.5e-19 67.7 0.1 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EEA05200.1 - 1.9e-05 24.2 0.5 7.4e-05 22.3 0.3 2.0 1 0 0 1 1 1 1 CNH domain Ribosomal_S4e PF00900.15 EEA05200.1 - 0.0054 16.3 0.2 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal family S4e AKAP95 PF04988.7 EEA05201.1 - 0.00062 19.5 0.6 0.0012 18.7 0.4 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 EEA05201.1 - 0.00085 19.3 2.9 0.002 18.1 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEA05201.1 - 0.0072 16.4 0.3 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Cortex-I_coil PF09304.5 EEA05201.1 - 0.022 14.7 3.8 0.12 12.3 0.9 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF3449 PF11931.3 EEA05201.1 - 0.13 11.7 3.7 0.18 11.3 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) zf-met PF12874.2 EEA05201.1 - 1.3 9.3 7.8 0.51 10.6 3.5 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Synaptobrevin PF00957.16 EEA05202.1 - 2.2e-21 75.2 1.6 5.3e-21 74.0 1.1 1.7 1 0 0 1 1 1 1 Synaptobrevin Myc_target_1 PF15179.1 EEA05202.1 - 0.094 12.2 0.2 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 WD40 PF00400.27 EEA05203.1 - 3.7e-26 90.0 22.7 4.3e-07 29.5 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEA05203.1 - 0.00043 18.5 3.6 0.25 9.4 0.1 3.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF3053 PF11254.3 EEA05204.1 - 0.055 12.7 0.6 0.096 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Peptidase_C71 PF12386.3 EEA05204.1 - 0.057 12.8 2.2 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei Guanylate_cyc PF00211.15 EEA05205.1 - 1.2e-68 230.1 2.4 9.5e-35 119.6 0.0 4.2 5 1 0 5 5 5 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 EEA05205.1 - 2.6e-08 33.2 0.0 2.6e-08 33.2 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Myb_DNA-binding PF00249.26 EEA05206.1 - 7.7e-44 147.5 7.4 2.3e-10 40.3 0.0 5.7 6 0 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA05206.1 - 4.6e-39 132.3 21.3 1.2e-12 47.6 0.9 6.8 3 1 4 7 7 7 5 Myb-like DNA-binding domain DUF603 PF04645.7 EEA05207.1 - 0.022 14.7 8.1 0.033 14.1 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 IncA PF04156.9 EEA05207.1 - 0.14 11.7 6.2 0.24 10.9 4.1 1.5 1 1 0 1 1 1 0 IncA protein LRS4 PF10422.4 EEA05207.1 - 0.18 11.1 8.4 0.24 10.6 5.8 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FlxA PF14282.1 EEA05207.1 - 0.54 10.2 8.4 0.043 13.7 2.4 1.7 2 0 0 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.2 EEA05207.1 - 2.1 8.1 5.9 0.29 10.9 1.3 1.6 2 0 0 2 2 2 0 Tropomyosin like HECT PF00632.20 EEA05208.1 - 1.8e-94 316.5 2.6 2.8e-94 315.8 0.1 2.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EEA05208.1 - 1.1e-08 34.9 8.3 1.3e-08 34.6 2.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4414) DUF1702 PF08012.6 EEA05208.1 - 7.9 4.9 0.0 13 4.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Prefoldin_2 PF01920.15 EEA05209.1 - 5.8e-16 58.1 14.5 6.6e-16 58.0 10.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EEA05209.1 - 0.0016 18.0 8.4 0.0069 16.0 5.8 1.8 1 1 0 1 1 1 1 Prefoldin subunit DUF2164 PF09932.4 EEA05209.1 - 0.013 15.2 0.2 0.037 13.8 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) H-kinase_dim PF02895.9 EEA05209.1 - 0.075 13.3 3.2 0.27 11.5 2.2 1.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF2096 PF09869.4 EEA05209.1 - 0.094 12.5 3.8 0.14 11.9 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Mod_r PF07200.8 EEA05209.1 - 0.13 12.1 10.9 0.23 11.3 7.6 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.7 EEA05209.1 - 0.15 11.8 2.3 0.13 12.0 0.6 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF87 PF01935.12 EEA05209.1 - 0.18 11.5 4.7 0.2 11.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Fib_alpha PF08702.5 EEA05209.1 - 0.24 11.5 9.6 0.57 10.2 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EEA05209.1 - 0.26 11.0 8.5 0.045 13.5 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) 5_3_exonuc PF01367.15 EEA05209.1 - 0.42 10.8 4.8 0.9 9.8 0.8 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold USP8_dimer PF08969.6 EEA05209.1 - 0.49 10.3 5.3 0.65 9.9 0.4 2.2 2 0 0 2 2 2 0 USP8 dimerisation domain DUF148 PF02520.12 EEA05209.1 - 1.3 8.8 11.2 6.8 6.5 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF948 PF06103.6 EEA05209.1 - 1.7 8.5 6.5 0.52 10.2 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1319 PF07028.6 EEA05209.1 - 2 8.6 11.3 2.3 8.3 2.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) Sas10_Utp3 PF04000.10 EEA05209.1 - 2.2 8.5 8.0 0.97 9.6 0.5 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family DUF2951 PF11166.3 EEA05209.1 - 2.3 8.1 6.6 0.65 9.8 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) HR1 PF02185.11 EEA05209.1 - 2.3 7.9 9.2 0.38 10.5 3.7 2.0 2 1 0 2 2 1 0 Hr1 repeat Nup54 PF13874.1 EEA05209.1 - 2.8 7.5 7.5 5.7 6.6 0.9 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Syntaxin PF00804.20 EEA05209.1 - 4.1 7.6 11.1 11 6.2 7.7 1.7 1 1 0 1 1 1 0 Syntaxin AAA_23 PF13476.1 EEA05209.1 - 6.7 6.9 13.1 7.6 6.8 9.1 1.0 1 0 0 1 1 1 0 AAA domain DUF21 PF01595.15 EEA05210.1 - 3.1e-32 111.3 2.5 5.2e-32 110.6 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 HABP4_PAI-RBP1 PF04774.10 EEA05211.1 - 9.1e-13 48.6 0.4 9.1e-13 48.6 0.3 2.4 2 1 0 3 3 3 1 Hyaluronan / mRNA binding family zf-CCCH_2 PF14608.1 EEA05212.1 - 1.2e-12 47.2 27.6 3.5e-06 26.7 1.8 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 EEA05212.1 - 4.5e-05 23.4 0.2 0.00012 22.1 0.1 1.7 1 1 0 1 1 1 1 PWI domain Glyoxal_oxid_N PF07250.6 EEA05212.1 - 0.0031 16.5 0.3 0.024 13.7 0.1 2.1 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus MRG PF05712.8 EEA05212.1 - 0.022 13.6 0.1 0.034 13.0 0.1 1.3 1 0 0 1 1 1 0 MRG Ribosomal_L14e PF01929.12 EEA05214.1 - 1.4e-23 83.0 1.5 1.9e-23 82.6 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EEA05214.1 - 0.021 14.5 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 KOW motif zf-C3HC4_3 PF13920.1 EEA05215.1 - 1.4e-13 50.2 13.3 1.4e-13 50.2 9.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05215.1 - 1.8e-07 31.0 14.7 5e-07 29.6 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA05215.1 - 1.7e-05 24.5 12.7 3.6e-05 23.4 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA05215.1 - 0.00034 20.2 11.8 0.00078 19.1 8.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EEA05215.1 - 8 6.0 9.8 28 4.3 6.8 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 EF-hand_1 PF00036.27 EEA05216.1 - 2.2e-21 73.4 10.5 3.9e-09 35.1 0.7 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EEA05216.1 - 2e-18 64.5 8.7 1.5e-06 27.5 0.3 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 EEA05216.1 - 1.3e-16 60.4 8.0 9e-13 48.1 2.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA05216.1 - 2.3e-15 55.9 8.5 1e-13 50.6 0.5 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EEA05216.1 - 1.7e-13 49.2 8.9 5.8e-05 22.2 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEA05216.1 - 4.6e-10 39.2 0.1 1.4e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain Arena_nucleocap PF00843.12 EEA05216.1 - 1.8e-05 22.8 0.0 2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Arenavirus nucleocapsid protein EF-hand_4 PF12763.2 EEA05216.1 - 0.01 15.5 3.0 0.041 13.6 0.5 2.3 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 EEA05216.1 - 0.046 14.0 1.7 0.13 12.5 0.4 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain Acetyltransf_11 PF13720.1 EEA05216.1 - 0.076 13.2 0.1 9.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SRI PF08236.6 EEA05216.1 - 0.096 12.6 0.2 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF3680 PF12441.3 EEA05216.1 - 1.8 8.4 4.7 3.6 7.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) 14-3-3 PF00244.15 EEA05218.1 - 4.4e-108 359.7 6.9 5.2e-108 359.5 4.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EEA05218.1 - 0.0027 17.6 1.6 0.047 13.6 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Cellulase-like PF12876.2 EEA05218.1 - 0.063 13.7 0.5 0.33 11.4 0.0 2.6 2 1 0 2 2 2 0 Sugar-binding cellulase-like Acyl-CoA_dh_2 PF08028.6 EEA05218.1 - 0.072 13.3 4.1 0.082 13.1 0.4 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain dsrm PF00035.20 EEA05218.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif TPR_14 PF13428.1 EEA05218.1 - 0.13 12.9 1.3 77 4.3 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat YkyA PF10368.4 EEA05218.1 - 3.2 7.0 12.5 2.4 7.4 3.0 2.5 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Ribosomal_L11_N PF03946.9 EEA05219.1 - 1.9e-16 59.2 0.1 3.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEA05219.1 - 2.6e-12 46.6 0.1 4.2e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain STIL_N PF15253.1 EEA05219.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus UBA_4 PF14555.1 EEA05220.1 - 2.9e-14 52.3 0.6 5.8e-14 51.3 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EEA05220.1 - 1.9e-11 43.8 0.0 4.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF3328 PF11807.3 EEA05220.1 - 0.08 12.6 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TAP_C PF03943.8 EEA05220.1 - 0.086 12.2 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Mitovir_RNA_pol PF05919.6 EEA05220.1 - 0.13 11.1 7.7 0.18 10.7 5.4 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Ribosomal_S13 PF00416.17 EEA05220.1 - 4.2 7.8 7.2 0.97 9.9 0.4 2.6 2 1 0 2 2 2 0 Ribosomal protein S13/S18 DUF443 PF04276.7 EEA05221.1 - 0.012 15.0 3.8 0.017 14.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) TAFII28 PF04719.9 EEA05221.1 - 0.031 14.0 0.1 0.073 12.8 0.1 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF4254 PF14063.1 EEA05221.1 - 0.084 12.4 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) NMD3 PF04981.8 EEA05223.1 - 3.2e-70 235.8 8.9 5.8e-70 235.0 6.2 1.4 1 0 0 1 1 1 1 NMD3 family ubiquitin PF00240.18 EEA05224.1 - 1.7e-12 46.5 0.0 4.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA05224.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_11 PF08241.7 EEA05225.1 - 2e-07 31.3 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA05225.1 - 9.8e-05 21.9 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA05225.1 - 0.0027 18.0 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA05225.1 - 0.014 15.8 0.5 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EEA05225.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Fib_alpha PF08702.5 EEA05226.1 - 0.04 14.0 1.6 0.055 13.6 1.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cnd1 PF12717.2 EEA05226.1 - 0.044 13.6 1.9 0.063 13.1 1.3 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEPN PF05168.9 EEA05226.1 - 0.072 12.9 0.8 0.19 11.6 0.2 1.8 1 1 1 2 2 2 0 HEPN domain Fes1 PF08609.5 EEA05226.1 - 2.9 8.4 6.3 7.1 7.1 0.2 2.6 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 IQ PF00612.22 EEA05227.1 - 2.2e-08 32.9 1.9 0.0033 16.9 0.0 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif IQ PF00612.22 EEA05228.1 - 5.8e-12 44.1 8.4 0.00015 21.1 0.6 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif PRANC PF09372.5 EEA05229.1 - 0.028 14.3 0.7 0.028 14.3 0.5 1.5 2 0 0 2 2 2 0 PRANC domain Phage_GP20 PF06810.6 EEA05229.1 - 0.63 9.4 5.7 1.2 8.5 3.9 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF1500 PF07389.7 EEA05230.1 - 0.43 10.6 9.8 1.3 9.0 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1500) PFK PF00365.15 EEA05231.1 - 2.1e-29 102.3 2.0 2.5e-21 75.8 0.1 2.5 2 0 0 2 2 2 2 Phosphofructokinase DUF1242 PF06842.7 EEA05232.1 - 1.6e-15 56.3 1.3 2.3e-15 55.8 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) SAP PF02037.22 EEA05233.1 - 1.1e-13 50.3 0.7 2.5e-13 49.1 0.5 1.7 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 EEA05233.1 - 0.11 12.3 0.7 0.29 10.9 0.5 1.8 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain Band_7 PF01145.20 EEA05234.1 - 8.1e-27 94.2 0.3 1.2e-26 93.7 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EEA05234.1 - 0.037 13.5 0.2 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 SPFH domain-Band 7 family HlyD PF00529.15 EEA05234.1 - 0.12 11.6 1.0 0.28 10.4 0.3 1.8 2 0 0 2 2 2 0 HlyD family secretion protein zf-U1 PF06220.7 EEA05235.1 - 3.8e-07 29.5 1.4 6.7e-07 28.7 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF1604 PF07713.8 EEA05235.1 - 0.02 14.6 1.6 0.039 13.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) IMS PF00817.15 EEA05235.1 - 0.093 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family DNA_pol_alpha_N PF12254.3 EEA05235.1 - 5.8 6.8 6.9 0.5 10.2 0.3 2.6 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal Rep_fac_C PF08542.6 EEA05236.1 - 2.1e-17 62.8 0.2 5.1e-17 61.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EEA05236.1 - 7.3e-16 58.5 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEA05236.1 - 6.4e-12 45.4 0.0 3.5e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EEA05236.1 - 3.5e-08 33.6 0.3 3.9e-06 26.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EEA05236.1 - 4.8e-08 32.9 0.0 9.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEA05236.1 - 3.2e-07 29.4 0.1 6.9e-05 21.7 0.0 2.6 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEA05236.1 - 2e-06 27.9 0.3 0.00049 20.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA05236.1 - 2.8e-06 26.5 0.1 1.1e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA05236.1 - 4.5e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEA05236.1 - 2.1e-05 24.2 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEA05236.1 - 4.7e-05 22.6 0.0 0.00094 18.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EEA05236.1 - 0.00019 21.2 0.6 0.16 11.6 0.0 2.4 1 1 1 2 2 2 2 NTPase AAA_3 PF07726.6 EEA05236.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEA05236.1 - 0.00061 19.3 0.1 0.0047 16.4 0.0 2.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_11 PF13086.1 EEA05236.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA05236.1 - 0.0042 16.5 0.2 0.17 11.2 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EEA05236.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EEA05236.1 - 0.0058 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 EEA05236.1 - 0.0063 15.3 0.0 0.066 11.9 0.0 2.2 1 1 1 2 2 2 1 ArgK protein DNA_pol3_delta PF06144.8 EEA05236.1 - 0.0071 15.8 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 EEA05236.1 - 0.0087 16.3 0.0 0.03 14.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain DEAD PF00270.24 EEA05236.1 - 0.01 15.3 0.0 0.96 8.9 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 EEA05236.1 - 0.011 15.8 0.1 0.072 13.1 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EEA05236.1 - 0.014 16.2 0.0 0.03 15.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEA05236.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA05236.1 - 0.017 14.5 0.0 0.08 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEA05236.1 - 0.019 15.0 0.0 0.085 13.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EEA05236.1 - 0.021 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 EEA05236.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ IstB_IS21 PF01695.12 EEA05236.1 - 0.036 13.4 0.3 0.15 11.4 0.2 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EEA05236.1 - 0.043 12.7 0.1 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 EEA05236.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EEA05236.1 - 0.11 12.1 0.2 0.53 9.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain GAF_3 PF13492.1 EEA05237.1 - 0.0018 18.3 0.0 3.2 7.8 0.0 3.0 3 1 0 3 3 3 2 GAF domain GAF_2 PF13185.1 EEA05237.1 - 0.0029 18.1 0.0 0.9 10.0 0.0 2.8 3 0 0 3 3 3 2 GAF domain GAF PF01590.21 EEA05237.1 - 0.055 13.5 0.0 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 GAF domain DSPc PF00782.15 EEA05238.1 - 1.8e-26 92.2 0.0 3.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA05238.1 - 8.9e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PP2C PF00481.16 EEA05239.1 - 2.2e-18 66.6 0.0 1.2e-10 41.2 0.0 2.9 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EEA05239.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Methylase_S PF01420.14 EEA05240.1 - 0.03 14.3 0.3 0.037 14.0 0.2 1.2 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Gly_acyl_tr_N PF06021.6 EEA05241.1 - 0.0054 16.1 1.2 0.012 15.0 0.2 2.0 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Hom_end PF05204.9 EEA05241.1 - 0.029 14.3 0.7 0.086 12.8 0.2 1.9 2 0 0 2 2 2 0 Homing endonuclease Pkinase PF00069.20 EEA05242.1 - 2e-70 236.9 0.0 2.3e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05242.1 - 1.6e-35 122.4 0.0 2.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA05242.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAST_1 PF06743.10 EEA05243.1 - 0.0033 17.0 5.7 14 5.5 0.0 5.1 3 1 2 5 5 5 3 FAST kinase-like protein, subdomain 1 Telomere_Sde2 PF13019.1 EEA05244.1 - 3.7e-10 39.7 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing FAD_binding_2 PF00890.19 EEA05245.1 - 3.2e-117 391.9 1.9 3.9e-117 391.6 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEA05245.1 - 4.4e-39 133.2 0.2 6.6e-39 132.7 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 EEA05245.1 - 0.00012 21.1 0.1 0.0032 16.4 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA05245.1 - 0.00024 20.2 0.0 0.17 10.9 0.0 3.0 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EEA05245.1 - 0.00089 18.2 0.1 0.14 10.9 0.2 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EEA05245.1 - 0.0031 17.4 2.6 0.065 13.0 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA05245.1 - 0.0085 15.1 0.1 0.017 14.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEA05245.1 - 0.23 9.8 0.3 1.4 7.3 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein Yae1_N PF09811.4 EEA05246.1 - 0.54 9.8 5.6 0.96 9.0 3.9 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal CRAL_TRIO PF00650.15 EEA05247.1 - 1.2e-25 89.8 0.3 2.6e-25 88.7 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA05247.1 - 0.00012 22.0 0.6 0.00036 20.4 0.4 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DIX PF00778.12 EEA05248.1 - 2.7e-06 26.9 0.1 4.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 DIX domain Profilin PF00235.14 EEA05249.1 - 1.4e-09 38.1 0.2 2.1e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Profilin FpoO PF10621.4 EEA05249.1 - 0.097 12.7 0.7 0.19 11.7 0.1 1.8 1 1 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO Glyco_hydro_31 PF01055.21 EEA05250.1 - 1.6e-89 300.7 8.6 2.3e-44 151.9 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA05250.1 - 4e-13 49.0 1.9 1.5e-12 47.2 1.3 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DEAD PF00270.24 EEA05251.1 - 7.6e-34 116.6 0.0 4.1e-33 114.2 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA05251.1 - 1.4e-23 82.4 0.0 3.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA05251.1 - 1.3e-21 75.8 0.5 1.3e-21 75.8 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA05251.1 - 0.00071 19.4 0.0 0.00071 19.4 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4064 PF13273.1 EEA05252.1 - 1 9.5 16.8 0.29 11.2 3.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF1049 PF06305.6 EEA05252.1 - 1.1 8.7 4.3 7.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF872 PF05915.7 EEA05252.1 - 5.1 6.9 8.8 0.59 10.0 1.8 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) START PF01852.14 EEA05253.1 - 3.1e-06 26.6 0.0 2.3e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 START domain RNase_P_p30 PF01876.11 EEA05254.1 - 8.4e-29 99.7 0.2 1.9e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit p30 PA14_2 PF10528.4 EEA05254.1 - 0.045 13.7 0.2 2 8.4 0.0 2.4 2 0 0 2 2 2 0 GLEYA domain DUF866 PF05907.8 EEA05255.1 - 2.6e-29 101.7 0.2 2.9e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GTP_EFTU PF00009.22 EEA05257.1 - 3.4e-38 130.9 0.1 5.3e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EEA05257.1 - 3.4e-33 113.5 0.0 7.2e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EEA05257.1 - 2.1e-12 47.0 0.2 6.4e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA05257.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dak1_2 PF13684.1 EEA05257.1 - 0.029 13.3 0.5 0.047 12.6 0.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family PAT1 PF09770.4 EEA05258.1 - 0.036 12.3 24.2 0.043 12.0 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Filament PF00038.16 EEA05259.1 - 0.0023 17.4 3.0 0.0032 16.9 2.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein TBPIP PF07106.8 EEA05259.1 - 0.062 12.8 5.4 0.18 11.3 3.8 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_UL6 PF01763.11 EEA05259.1 - 0.38 8.8 3.1 0.72 7.9 1.8 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like Prefoldin_2 PF01920.15 EEA05259.1 - 0.45 10.2 6.5 5 6.9 1.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit HR1 PF02185.11 EEA05259.1 - 1.6 8.5 9.3 0.78 9.5 0.1 2.9 1 1 1 2 2 2 0 Hr1 repeat DUF2730 PF10805.3 EEA05259.1 - 1.7 8.4 5.3 16 5.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF972 PF06156.8 EEA05259.1 - 2.3 8.5 7.5 46 4.4 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CAML PF14963.1 EEA05260.1 - 0.15 11.4 0.3 0.19 11.0 0.2 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UAA PF08449.6 EEA05262.1 - 1.2e-68 231.2 24.5 2.4e-68 230.2 17.0 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEA05262.1 - 2e-10 40.5 7.6 2e-10 40.5 5.3 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EEA05262.1 - 5.2e-10 39.4 29.4 1.8e-09 37.7 6.7 3.6 3 1 1 4 4 4 2 EamA-like transporter family SIT PF15330.1 EEA05262.1 - 0.058 13.5 0.1 9.6 6.3 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT EmrE PF13536.1 EEA05262.1 - 6.7 6.9 27.8 2.1 8.5 1.9 3.0 3 1 0 3 3 3 0 Multidrug resistance efflux transporter TPR_11 PF13414.1 EEA05263.1 - 5.5e-09 35.5 0.5 1.3e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEA05263.1 - 7.8e-07 28.5 0.0 0.026 14.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA05263.1 - 2.1e-05 24.3 0.0 7.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA05263.1 - 0.00014 21.3 5.0 0.008 15.7 0.6 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA05263.1 - 0.00014 21.3 7.0 0.00053 19.5 1.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_28 PF02636.12 EEA05263.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EEA05263.1 - 0.00098 19.5 2.1 0.021 15.2 0.0 3.8 3 1 1 4 4 4 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 EEA05263.1 - 0.26 11.8 0.0 0.56 10.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pkinase PF00069.20 EEA05264.1 - 1.4e-73 247.2 0.0 1.7e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05264.1 - 4.7e-37 127.4 0.0 6.1e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEA05264.1 - 0.0042 16.4 0.3 0.014 14.7 0.2 1.7 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EEA05264.1 - 0.011 15.4 0.1 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEA05264.1 - 0.023 13.7 0.0 0.065 12.2 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHCH PF06747.8 EEA05266.1 - 0.00055 19.7 10.3 0.0072 16.2 3.9 2.6 2 1 0 2 2 2 2 CHCH domain COX6B PF02297.12 EEA05266.1 - 0.21 11.6 11.3 9.7 6.2 7.8 2.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb MRP-L47 PF06984.8 EEA05266.1 - 0.39 10.6 2.6 2.4 8.0 0.5 2.3 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF1546 PF07571.8 EEA05267.1 - 0.00079 19.4 0.1 0.058 13.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EEA05267.1 - 0.021 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) HEAT PF02985.17 EEA05268.1 - 0.024 14.6 0.0 5.2 7.4 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat DUF1302 PF06980.6 EEA05268.1 - 0.055 12.0 0.2 0.082 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Peptidase_C50 PF03568.12 EEA05269.1 - 1.1e-26 93.3 12.2 4e-16 58.6 8.4 5.5 4 2 0 4 4 4 2 Peptidase family C50 Rsc14 PF08586.5 EEA05271.1 - 2 8.9 7.6 8.9 6.8 0.1 4.4 5 0 0 5 5 5 0 RSC complex, Rsc14/Ldb7 subunit NOT2_3_5 PF04153.13 EEA05272.1 - 1.8e-33 115.2 9.8 3.7e-33 114.2 6.8 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Sec34 PF04136.10 EEA05272.1 - 0.57 9.8 14.0 0.029 14.0 2.8 2.4 2 1 1 3 3 3 0 Sec34-like family BLOC1_2 PF10046.4 EEA05272.1 - 0.87 9.7 11.2 0.053 13.6 1.2 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.4 EEA05272.1 - 2.8 7.8 8.4 0.62 10.0 1.9 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 UQ_con PF00179.21 EEA05273.1 - 6.7e-41 138.9 0.0 7.5e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA05273.1 - 1.3e-06 28.1 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 EEA05273.1 - 0.059 12.8 0.0 0.084 12.3 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Kin17_mid PF10357.4 EEA05274.1 - 7.8e-42 141.9 6.2 7.8e-42 141.9 4.3 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EEA05274.1 - 0.0014 18.7 2.8 0.0031 17.6 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA05274.1 - 0.0035 17.4 2.7 0.009 16.1 1.9 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3228 PF11539.3 EEA05274.1 - 0.024 13.7 2.7 0.04 13.0 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3228) DUF4430 PF14478.1 EEA05274.1 - 0.054 13.5 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) YhdB PF14148.1 EEA05276.1 - 0.079 12.7 1.3 0.28 10.9 0.1 2.5 2 1 1 3 3 3 0 YhdB-like protein UQ_con PF00179.21 EEA05277.1 - 7.3e-45 151.8 0.2 8.3e-45 151.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA05277.1 - 7.7e-05 22.4 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA05277.1 - 0.026 14.4 1.5 0.06 13.2 1.0 1.9 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EEA05277.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C1 PF00112.18 EEA05278.1 - 2.3e-40 138.8 9.1 4.1e-40 137.9 6.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EEA05278.1 - 0.011 14.2 0.5 0.046 12.2 0.2 2.1 2 1 1 3 3 3 0 Peptidase C1-like family SLBP_RNA_bind PF15247.1 EEA05281.1 - 7e-20 70.5 2.0 1.5e-19 69.5 1.4 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain TFIID_20kDa PF03847.8 EEA05281.1 - 0.00079 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EEA05281.1 - 0.023 14.8 0.3 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 MitMem_reg PF13012.1 EEA05282.1 - 3.2e-29 101.3 0.0 5.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EEA05282.1 - 8.2e-27 93.2 0.1 1.2e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EcoR124_C PF12008.3 EEA05282.1 - 0.052 12.7 0.2 0.088 11.9 0.1 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Herpes_BBRF1 PF04793.7 EEA05282.1 - 0.057 12.1 0.7 8.4 5.0 0.0 2.5 3 0 0 3 3 3 0 BRRF1-like protein Dicty_CAR PF05462.6 EEA05282.1 - 0.066 12.0 0.4 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Pox_MCEL PF03291.11 EEA05283.1 - 9.8e-38 129.8 11.1 9.6e-36 123.2 7.7 2.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EEA05283.1 - 1.3e-13 50.8 0.2 2.5e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA05283.1 - 4.2e-12 46.3 0.0 1.2e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA05283.1 - 8.6e-10 39.1 0.0 3.1e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA05283.1 - 1.4e-09 38.3 0.0 3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA05283.1 - 4.1e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA05283.1 - 1.1e-07 31.7 0.0 3.4e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEA05283.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EEA05283.1 - 0.058 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.14 EEA05283.1 - 0.07 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family NodS PF05401.6 EEA05283.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 EEA05283.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MCM PF00493.18 EEA05284.1 - 3.6e-131 436.8 1.3 4.7e-131 436.5 0.9 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA05284.1 - 3.5e-26 92.0 0.1 1.5e-25 89.9 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA05284.1 - 3.5e-06 26.3 0.0 2.7e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA05284.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EEA05284.1 - 0.034 13.6 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EEA05284.1 - 0.048 14.0 0.3 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CTP_transf_2 PF01467.21 EEA05286.1 - 2.4e-24 86.1 0.0 5.9e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EEA05286.1 - 0.0014 18.3 0.5 0.31 10.6 0.0 2.7 2 1 1 3 3 3 2 FAD synthetase Pantoate_ligase PF02569.10 EEA05286.1 - 0.1 11.3 0.0 0.7 8.6 0.0 2.0 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Hexapep PF00132.19 EEA05288.1 - 1.8e-08 33.5 5.9 2.1e-05 23.7 0.1 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EEA05288.1 - 0.021 13.3 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Zn_clus PF00172.13 EEA05289.1 - 0.24 11.3 7.1 0.59 10.0 4.9 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MyTH4 PF00784.12 EEA05290.1 - 7.3e-13 48.4 0.5 2.7e-12 46.6 0.1 2.2 2 0 0 2 2 2 1 MyTH4 domain IPK PF03770.11 EEA05291.1 - 6.7e-15 55.2 1.5 1.9e-13 50.5 1.0 2.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase LRR_8 PF13855.1 EEA05292.1 - 7.5e-07 28.8 1.7 7.5e-07 28.8 1.2 3.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EEA05292.1 - 1.7e-06 27.4 12.9 5.7e-05 22.6 0.9 5.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEA05292.1 - 0.1 12.7 0.2 0.1 12.7 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Maf1 PF09174.5 EEA05293.1 - 5.9e-44 150.0 0.8 7.7e-44 149.6 0.5 1.2 1 0 0 1 1 1 1 Maf1 regulator Zip PF02535.17 EEA05294.1 - 0.092 11.7 13.2 0.11 11.4 9.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Rhomboid PF01694.17 EEA05295.1 - 2.7e-27 95.6 16.5 2.7e-27 95.6 11.4 2.4 3 0 0 3 3 3 1 Rhomboid family HEAT_EZ PF13513.1 EEA05296.1 - 1.9e-13 50.4 9.4 1.7e-07 31.5 0.0 7.3 6 1 2 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EEA05296.1 - 1.1e-09 37.5 13.0 0.0034 17.3 0.0 8.9 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.1 EEA05296.1 - 2.4e-09 37.3 0.8 0.002 18.3 0.0 5.3 3 2 2 5 5 5 3 HEAT repeats IBN_N PF03810.14 EEA05296.1 - 2.2e-08 33.8 5.6 6.2e-08 32.4 0.3 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EEA05296.1 - 9e-05 22.7 0.5 1.3 9.4 0.0 3.7 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EEA05296.1 - 0.12 12.2 8.6 16 5.4 0.5 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EEA05298.1 - 4.7e-34 117.7 0.1 4.4e-33 114.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05298.1 - 1.1e-05 24.6 0.0 3.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Spc97_Spc98 PF04130.8 EEA05299.1 - 6.7e-52 176.5 27.6 1.3e-51 175.6 19.1 1.6 1 0 0 1 1 1 1 Spc97 / Spc98 family Med4 PF10018.4 EEA05300.1 - 0.037 13.4 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RdRP PF05183.7 EEA05300.1 - 0.07 11.8 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF2244 PF10003.4 EEA05300.1 - 0.12 11.7 1.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Tropomyosin_1 PF12718.2 EEA05300.1 - 0.16 11.7 2.3 0.26 11.1 1.6 1.2 1 0 0 1 1 1 0 Tropomyosin like Pkinase PF00069.20 EEA05301.1 - 1.2e-47 162.3 0.0 5.1e-32 111.0 0.0 2.8 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05301.1 - 2e-24 86.0 0.0 7.8e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA05301.1 - 2.3e-05 23.5 0.1 0.039 12.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like LsmAD PF06741.8 EEA05303.1 - 7.2e-15 54.8 2.8 7.2e-15 54.8 1.9 2.7 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 EEA05303.1 - 8.4e-08 32.0 0.6 2.2e-07 30.6 0.0 2.1 3 0 0 3 3 3 1 Ataxin 2 SM domain PAM2 PF07145.10 EEA05303.1 - 0.0018 17.6 1.1 0.0036 16.7 0.8 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF3675 PF12428.3 EEA05303.1 - 0.037 14.2 0.1 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) S1-P1_nuclease PF02265.11 EEA05304.1 - 7e-24 84.8 0.0 1.2e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4181 PF13789.1 EEA05304.1 - 0.33 10.9 5.7 2 8.3 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) TPP_enzyme_N PF02776.13 EEA05305.1 - 3.7e-29 101.3 0.0 1.2e-28 99.8 0.0 1.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA05305.1 - 1.4e-21 76.6 0.0 1.1e-20 73.7 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEA05305.1 - 1.1e-17 64.0 0.0 2.9e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EEA05305.1 - 0.02 14.4 0.1 0.05 13.1 0.1 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit COPIIcoated_ERV PF07970.7 EEA05306.1 - 2.3e-56 190.8 2.2 3.1e-56 190.4 1.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEA05306.1 - 9.7e-27 92.8 1.9 1.3e-26 92.4 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-RanBP PF00641.13 EEA05306.1 - 2.8 7.1 6.7 0.35 10.0 0.1 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Fzo_mitofusin PF04799.8 EEA05307.1 - 0.0024 17.2 2.6 0.83 9.0 0.6 2.4 2 0 0 2 2 2 2 fzo-like conserved region DUF722 PF05263.6 EEA05307.1 - 0.016 15.3 2.5 0.033 14.3 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF722) PocR PF10114.4 EEA05307.1 - 0.043 12.9 2.4 1.8 7.6 0.6 2.2 2 0 0 2 2 2 0 Sensory domain found in PocR Allexi_40kDa PF05549.6 EEA05307.1 - 0.043 13.0 3.4 0.065 12.5 2.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CDC37_N PF03234.9 EEA05307.1 - 0.053 13.8 7.9 0.08 13.2 5.5 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding ThylakoidFormat PF11264.3 EEA05307.1 - 0.46 10.0 6.4 0.26 10.8 0.8 2.4 1 1 1 2 2 2 0 Thylakoid formation protein Z1 PF10593.4 EEA05307.1 - 2.2 7.4 6.4 4 6.5 4.1 1.8 1 1 0 1 1 1 0 Z1 domain LMBR1 PF04791.11 EEA05308.1 - 1.8e-15 56.5 41.8 1.2e-14 53.8 28.9 1.9 1 1 0 1 1 1 1 LMBR1-like membrane protein Scs3p PF10261.4 EEA05309.1 - 0.0017 17.4 5.3 0.0017 17.4 3.7 2.1 2 1 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM PufQ PF05398.6 EEA05309.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 PufQ cytochrome subunit Thioredoxin PF00085.15 EEA05310.1 - 8.9e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EEA05310.1 - 0.00012 20.9 0.6 0.00014 20.6 0.4 1.1 1 0 0 1 1 1 1 Phosducin DUF4510 PF14971.1 EEA05310.1 - 0.067 13.3 0.6 0.093 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) EF-1_beta_acid PF10587.4 EEA05310.1 - 0.79 9.9 4.4 1.2 9.3 0.1 2.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Cpn60_TCP1 PF00118.19 EEA05311.1 - 1.6e-143 478.8 8.5 1.9e-143 478.6 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-CCCH PF00642.19 EEA05312.1 - 7.9e-07 28.6 3.7 1.7e-05 24.3 0.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA05312.1 - 0.4 10.7 3.2 3 7.9 0.0 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EEA05313.1 - 4.1e-09 35.9 14.3 1.6e-05 24.4 0.9 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-DHHC PF01529.15 EEA05314.1 - 1.8e-35 121.9 11.7 1.8e-35 121.9 8.1 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Rod_cone_degen PF15201.1 EEA05314.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF35_N PF12172.3 EEA05314.1 - 0.049 13.5 2.0 0.12 12.2 1.4 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF4497 PF14924.1 EEA05316.1 - 0.025 14.8 1.6 4.2 7.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4497) DXPR_C PF13288.1 EEA05316.1 - 0.046 13.7 0.4 0.18 11.8 0.3 2.0 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain EcsB PF05975.7 EEA05316.1 - 0.05 12.0 0.0 0.078 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB IQ-like PF15157.1 EEA05316.1 - 1.4 9.1 4.5 0.79 9.9 1.1 2.0 2 1 0 2 2 2 0 IQ-like SLBP_RNA_bind PF15247.1 EEA05317.1 - 1.9e-20 72.3 1.0 4.4e-20 71.2 0.7 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain DNA_RNApol_7kD PF03604.8 EEA05318.1 - 2e-15 55.9 5.7 2.7e-15 55.5 3.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EEA05318.1 - 0.007 16.0 0.7 0.0079 15.8 0.5 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EEA05318.1 - 0.0086 15.8 1.1 0.012 15.4 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 EEA05318.1 - 0.028 14.3 2.7 2.3 8.2 0.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 EEA05318.1 - 0.033 14.1 1.3 0.056 13.4 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF2296 PF10058.4 EEA05318.1 - 0.058 13.1 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF2757 PF10955.3 EEA05318.1 - 0.058 13.5 0.3 0.092 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) zf-ISL3 PF14690.1 EEA05318.1 - 0.067 13.2 4.1 0.21 11.6 1.2 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2318 PF10080.4 EEA05318.1 - 0.093 12.5 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_3 PF07649.7 EEA05318.1 - 0.18 11.8 3.3 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 C1-like domain Nudix_N_2 PF14803.1 EEA05318.1 - 0.19 11.4 3.1 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF2197 PF09963.4 EEA05318.1 - 0.2 11.6 2.3 3.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF3268 PF11672.3 EEA05318.1 - 0.24 11.4 1.9 0.79 9.8 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) OrfB_Zn_ribbon PF07282.6 EEA05318.1 - 0.29 10.8 3.6 0.091 12.4 0.8 1.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EEA05318.1 - 0.36 10.6 5.6 2.2 8.1 1.4 2.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Chordopox_RPO7 PF05864.7 EEA05318.1 - 0.41 10.7 3.0 3 8.0 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_L37e PF01907.14 EEA05318.1 - 5.7 6.8 6.7 12 5.7 1.9 2.1 1 1 1 2 2 2 0 Ribosomal protein L37e NPHI_C PF08469.5 EEA05321.1 - 0.0018 18.1 0.2 0.0066 16.3 0.1 1.9 1 0 0 1 1 1 1 Nucleoside triphosphatase I C-terminal SWIB PF02201.13 EEA05321.1 - 0.014 15.0 0.0 0.045 13.4 0.0 1.9 1 0 0 1 1 1 0 SWIB/MDM2 domain HEAT PF02985.17 EEA05322.1 - 4.8e-16 57.3 5.7 2.4e-05 24.0 0.0 9.3 9 1 1 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EEA05322.1 - 1.2e-13 51.1 0.0 4.8e-07 29.9 0.0 6.4 5 2 2 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EEA05322.1 - 3.2e-11 43.3 0.3 0.0023 18.3 0.0 7.3 7 1 2 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA05322.1 - 1.4e-07 31.7 3.2 0.048 14.0 0.0 6.2 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EEA05322.1 - 0.00079 19.3 8.5 2 8.4 0.0 6.8 7 1 1 8 8 8 2 UME (NUC010) domain IBN_N PF03810.14 EEA05322.1 - 0.0036 17.1 2.0 0.32 10.9 0.5 3.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EEA05322.1 - 0.0042 16.8 1.4 3.3 7.6 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Katanin_con80 PF13925.1 EEA05322.1 - 0.029 14.1 0.4 2.8 7.6 0.0 3.3 3 0 0 3 3 3 0 con80 domain of Katanin UPF0172 PF03665.8 EEA05323.1 - 4.5e-28 98.0 0.1 5.4e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EEA05323.1 - 0.0039 16.9 0.0 0.0059 16.3 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CLPTM1 PF05602.7 EEA05325.1 - 3.9e-78 263.1 12.8 5.7e-78 262.5 8.9 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EEA05325.1 - 0.0013 18.2 3.6 0.022 14.2 0.2 3.3 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.13 EEA05326.1 - 5.4e-28 98.3 15.9 1.5e-27 96.8 11.1 1.8 1 1 0 1 1 1 1 ER lumen protein retaining receptor Rnf-Nqr PF02508.9 EEA05326.1 - 0.017 14.7 0.4 0.017 14.7 0.3 1.7 2 1 0 2 2 2 0 Rnf-Nqr subunit, membrane protein Bac_rhodopsin PF01036.13 EEA05326.1 - 0.076 12.3 7.4 0.055 12.7 1.0 2.3 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein DUF3816 PF12822.2 EEA05326.1 - 1.2 8.9 19.6 0.048 13.5 5.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Urm1 PF09138.6 EEA05327.1 - 1.1e-32 112.0 0.3 1.2e-32 111.8 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EEA05327.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 ThiS family FHA PF00498.21 EEA05328.1 - 7.1e-17 61.2 1.3 5.4e-09 36.0 0.3 2.8 2 0 0 2 2 2 2 FHA domain zf-C3HC4_3 PF13920.1 EEA05328.1 - 5.9e-09 35.4 9.4 1.3e-08 34.3 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA05328.1 - 3.9e-07 29.8 11.4 1.1e-06 28.4 7.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEA05328.1 - 3.2e-06 27.0 14.4 3.2e-06 27.0 10.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA05328.1 - 4.6e-06 26.3 13.9 4.6e-06 26.3 9.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA05328.1 - 1.3e-05 24.7 12.5 3e-05 23.5 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA05328.1 - 0.00012 21.6 6.7 0.00012 21.6 4.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEA05328.1 - 0.00018 21.1 12.4 0.00038 20.1 8.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EEA05328.1 - 0.28 10.8 8.4 0.036 13.6 2.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEA05328.1 - 1.9 8.6 7.4 1.2 9.2 2.7 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger ELMO_CED12 PF04727.8 EEA05329.1 - 2.1e-38 131.5 0.0 3e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Tap-RNA_bind PF09162.5 EEA05329.1 - 0.026 14.0 0.1 0.081 12.5 0.1 1.8 1 0 0 1 1 1 0 Tap, RNA-binding Topoisom_I PF01028.15 EEA05330.1 - 1.2e-91 305.9 5.5 2.5e-91 304.9 3.8 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 EEA05330.1 - 1.3e-84 282.7 6.8 1.3e-84 282.7 4.7 2.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 EEA05330.1 - 3.8e-30 103.3 0.9 3.8e-30 103.3 0.6 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain Patatin PF01734.17 EEA05334.1 - 4e-14 53.0 0.0 8.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TALPID3 PF15324.1 EEA05334.1 - 0.44 7.8 0.6 0.6 7.3 0.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Cid2 PF09774.4 EEA05335.1 - 0.32 11.0 5.7 0.082 13.0 0.8 2.0 2 0 0 2 2 2 0 Caffeine-induced death protein 2 SNF5 PF04855.7 EEA05337.1 - 0.0016 17.9 0.3 0.0039 16.7 0.2 1.6 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pyr_redox_dim PF02852.17 EEA05338.1 - 4.9e-32 110.2 0.4 2.4e-31 108.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EEA05338.1 - 1.3e-23 83.9 0.0 2.7e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA05338.1 - 1.3e-18 67.1 0.1 4e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA05338.1 - 7.2e-05 22.9 0.0 0.09 12.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA05338.1 - 0.0024 16.8 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EEA05338.1 - 0.013 14.5 1.9 2.2 7.2 0.4 2.2 1 1 1 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EEA05338.1 - 0.045 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EEA05338.1 - 0.09 11.6 0.5 12 4.6 0.3 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase AstA PF04958.7 EEA05338.1 - 0.15 10.4 0.0 0.26 9.6 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Pkinase PF00069.20 EEA05339.1 - 7.3e-52 176.0 0.2 4.2e-51 173.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05339.1 - 6.9e-50 169.5 0.0 1.9e-49 168.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05339.1 - 0.00063 18.7 0.0 0.0017 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEA05339.1 - 0.00081 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Synaptobrevin PF00957.16 EEA05340.1 - 3.4e-06 26.5 0.1 1e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Synaptobrevin HTH_WhiA PF02650.9 EEA05340.1 - 0.038 14.3 0.3 0.069 13.5 0.2 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain MFS_1 PF07690.11 EEA05341.1 - 3.7e-23 81.8 41.4 1.8e-21 76.2 5.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA05341.1 - 9.1e-17 60.7 7.5 9.1e-17 60.7 5.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEA05341.1 - 0.0018 16.4 1.3 0.0018 16.4 0.9 3.7 3 2 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family tRNA_int_end_N2 PF12928.2 EEA05342.1 - 0.00027 20.3 0.9 0.0011 18.3 0.2 2.4 2 1 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term Na_Ca_ex PF01699.19 EEA05343.1 - 2.1e-10 40.3 4.7 2.6e-10 40.0 3.3 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein CTP_transf_2 PF01467.21 EEA05345.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase Ribosomal_L1 PF00687.16 EEA05346.1 - 2e-48 164.6 3.2 2e-48 164.6 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family Leo1 PF04004.8 EEA05347.1 - 2.9e-13 49.8 0.2 9.2e-13 48.2 0.0 1.9 2 1 0 2 2 2 1 Leo1-like protein Helicase_C_2 PF13307.1 EEA05348.1 - 9.7e-44 149.2 0.1 2.8e-43 147.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEA05348.1 - 3.9e-36 124.0 2.5 3.9e-36 124.0 1.8 2.1 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 EEA05348.1 - 0.012 15.4 5.1 0.11 12.2 0.1 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit TypeIII_RM_meth PF12564.3 EEA05348.1 - 2.1 8.3 12.3 0.79 9.7 0.5 3.4 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit GATA PF00320.22 EEA05350.1 - 0.002 17.4 4.8 0.023 14.0 3.4 2.5 1 1 0 1 1 1 1 GATA zinc finger Rieske_2 PF13806.1 EEA05350.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain CBFD_NFYB_HMF PF00808.18 EEA05351.1 - 1.6e-08 34.4 0.0 2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA05351.1 - 0.00092 19.2 0.1 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 EEA05351.1 - 0.0059 15.8 0.0 0.0073 15.6 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Tetraspannin PF00335.15 EEA05352.1 - 7.2 5.8 20.0 9.3 5.4 13.1 1.6 1 1 0 1 1 1 0 Tetraspanin family Alpha_adaptinC2 PF02883.15 EEA05353.1 - 6.1e-07 29.7 0.0 2.2e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain HALZ PF02183.13 EEA05353.1 - 0.045 13.4 0.8 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.20 EEA05354.1 - 4.4e-63 212.8 0.1 7.1e-63 212.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05354.1 - 2.1e-23 82.7 0.3 7.8e-22 77.5 0.2 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA05354.1 - 0.0024 16.9 0.1 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 EEA05355.1 - 7.8e-74 248.1 1.4 7.8e-74 248.1 1.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA05355.1 - 7.3e-15 54.6 0.0 2.4e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EEA05355.1 - 5.6e-11 42.0 1.9 1.9e-10 40.3 1.3 2.0 1 0 0 1 1 1 1 HSA PA28_beta PF02252.13 EEA05356.1 - 4.1e-61 204.8 0.2 7.4e-61 204.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit V-SNARE PF05008.10 EEA05356.1 - 0.098 12.8 0.1 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus tRNA-synt_1 PF00133.17 EEA05357.1 - 1.1e-180 601.6 0.0 6.8e-180 599.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA05357.1 - 5.6e-33 113.8 1.5 5.6e-33 113.8 1.1 2.2 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEA05357.1 - 7e-16 57.8 3.9 6.9e-07 28.2 0.1 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEA05357.1 - 3.3e-08 33.0 0.1 1.3e-06 27.8 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EEA05357.1 - 0.0051 15.9 0.9 0.033 13.3 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EEA05357.1 - 0.017 13.9 0.0 0.13 10.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (R) WD40 PF00400.27 EEA05358.1 - 3e-13 49.0 9.6 0.094 12.6 0.7 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat AP2 PF00847.15 EEA05360.1 - 4.7e-13 49.0 3.0 1.1e-12 47.9 2.1 1.6 1 0 0 1 1 1 1 AP2 domain COG5 PF10392.4 EEA05362.1 - 0.025 14.5 0.3 0.048 13.6 0.1 1.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Pex14_N PF04695.8 EEA05362.1 - 0.16 12.0 1.6 0.21 11.6 1.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ParA PF10609.4 EEA05363.1 - 7.1e-30 102.7 0.5 1.8e-29 101.4 0.3 1.7 1 1 1 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EEA05363.1 - 5.3e-16 58.6 0.0 8.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA05363.1 - 2e-06 27.7 0.0 8.9e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EEA05363.1 - 2.4e-05 23.5 3.9 0.00043 19.4 0.0 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 EEA05363.1 - 5.2e-05 22.4 0.0 9.8e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 EEA05363.1 - 0.0007 18.8 0.1 1 8.4 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EEA05363.1 - 0.016 14.8 0.5 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EEA05363.1 - 0.039 12.6 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EEA05363.1 - 0.047 12.8 0.1 0.097 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEA05363.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA05363.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fcf2 PF08698.6 EEA05364.1 - 8e-20 70.6 0.1 1.8e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing DUF3484 PF11983.3 EEA05364.1 - 0.046 14.5 0.1 0.11 13.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) RNase_H2_suC PF08615.6 EEA05365.1 - 6.2e-15 55.2 0.2 2.4e-13 50.1 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PTH2 PF01981.11 EEA05366.1 - 1e-43 147.6 0.0 1.2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF1934 PF09148.5 EEA05366.1 - 0.14 11.8 0.1 0.57 9.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1934) Condensin2nSMC PF12422.3 EEA05367.1 - 1.6e-46 157.8 0.3 6.9e-46 155.7 0.2 2.2 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 EEA05367.1 - 3.9e-05 23.3 0.9 0.073 13.1 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EEA05367.1 - 0.095 12.9 0.0 0.77 10.0 0.0 2.5 2 1 1 3 3 3 0 HEAT repeats TFCD_C PF12612.3 EEA05367.1 - 0.84 9.0 7.9 1.2 8.5 0.1 4.2 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal ERO1 PF04137.10 EEA05368.1 - 3.6e-41 141.3 11.3 4.2e-38 131.2 7.8 2.3 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Clr5 PF14420.1 EEA05368.1 - 0.013 15.3 0.2 0.03 14.2 0.2 1.6 1 0 0 1 1 1 0 Clr5 domain Peptidase_C12 PF01088.16 EEA05369.1 - 2.8e-45 154.1 0.0 3.5e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UvrD-helicase PF00580.16 EEA05370.1 - 6.9e-54 183.2 3.3 6.9e-54 183.2 2.3 2.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EEA05370.1 - 4.3e-45 154.7 11.7 3.1e-34 118.9 0.0 4.2 3 2 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EEA05370.1 - 2.5e-10 39.9 0.0 6.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EEA05370.1 - 7.2e-10 38.9 0.0 2.6e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EEA05370.1 - 0.00027 20.5 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEA05370.1 - 0.025 14.0 0.2 0.25 10.8 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF3223 PF11523.3 EEA05371.1 - 2.3e-17 63.0 0.7 1.8e-16 60.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) La PF05383.12 EEA05371.1 - 4.5e-13 48.7 0.3 1.1e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 La domain AP2 PF00847.15 EEA05372.1 - 7.9e-12 45.1 2.2 1.8e-11 44.0 1.5 1.7 1 0 0 1 1 1 1 AP2 domain ABC1 PF03109.11 EEA05374.1 - 6.6e-22 77.7 0.0 1.7e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 ABC1 family Arm PF00514.18 EEA05375.1 - 7.3e-81 263.5 11.1 4.3e-12 45.3 0.0 10.2 10 0 0 10 10 10 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEA05375.1 - 2.9e-24 85.1 0.0 4.6e-06 26.8 0.0 6.3 2 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EEA05375.1 - 2.7e-20 72.2 0.0 2.9e-05 24.4 0.0 5.6 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EEA05375.1 - 7.8e-18 62.9 0.6 0.0047 16.8 0.0 7.8 9 0 0 9 9 9 3 HEAT repeat IBB PF01749.15 EEA05375.1 - 1e-11 44.8 0.2 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 EEA05375.1 - 0.00021 19.7 0.0 0.044 12.1 0.0 2.9 2 2 0 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 EEA05375.1 - 0.00028 19.2 0.0 0.023 12.9 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 EEA05375.1 - 0.00037 19.7 0.0 1.4 7.9 0.0 2.6 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_C PF11698.3 EEA05375.1 - 0.0051 16.7 0.0 8.6 6.3 0.0 3.9 2 1 3 5 5 5 1 V-ATPase subunit H ParcG PF10274.4 EEA05375.1 - 0.1 12.4 0.4 12 5.7 0.0 3.0 2 1 2 4 4 4 0 Parkin co-regulated protein DnaJ-X PF14308.1 EEA05376.1 - 6.2e-56 188.8 9.1 1.1e-55 188.1 6.3 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EEA05376.1 - 6.9e-26 89.7 3.4 1.6e-25 88.6 2.3 1.6 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.6 EEA05376.1 - 8e-05 22.7 1.7 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain Med10 PF09748.4 EEA05377.1 - 5.8e-08 32.6 0.2 8.3e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex IncA PF04156.9 EEA05377.1 - 0.42 10.1 3.4 0.67 9.5 0.2 1.9 1 1 1 2 2 2 0 IncA protein PIP5K PF01504.13 EEA05378.1 - 6.8e-78 261.2 5.9 1.6e-77 260.0 4.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_7 PF13499.1 EEA05378.1 - 0.00029 20.9 0.3 0.0011 19.0 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA05378.1 - 0.0011 18.0 1.1 0.005 16.0 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EEA05378.1 - 0.0013 18.4 2.4 0.045 13.6 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EEA05378.1 - 0.0026 17.0 0.0 0.0082 15.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EEA05378.1 - 0.034 13.7 1.9 0.074 12.6 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair Methyltransf_11 PF08241.7 EEA05379.1 - 1e-13 51.5 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA05379.1 - 1.3e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA05379.1 - 1.8e-11 44.0 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA05379.1 - 7.8e-11 42.3 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA05379.1 - 2.7e-07 31.1 0.0 4.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA05379.1 - 7.7e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA05379.1 - 2.1e-05 23.7 0.0 2.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEA05379.1 - 2.3e-05 24.4 0.0 0.00023 21.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EEA05379.1 - 7.8e-05 21.8 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 EEA05379.1 - 0.00024 20.1 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_24 PF13578.1 EEA05379.1 - 0.0036 18.1 0.0 0.0065 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA05379.1 - 0.004 16.5 0.0 0.0077 15.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EEA05379.1 - 0.01 14.8 0.0 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 EEA05379.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EEA05379.1 - 0.13 11.8 0.0 0.51 9.9 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase Kinesin PF00225.18 EEA05380.1 - 1.9e-93 312.8 2.3 3.3e-93 312.0 1.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF4149 PF13664.1 EEA05381.1 - 0.072 13.1 4.7 0.17 11.9 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) SBDS PF01172.13 EEA05382.1 - 1.1e-33 114.8 0.1 2.7e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EEA05382.1 - 3.3e-25 88.1 0.0 6.1e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain Cohesin PF00963.13 EEA05382.1 - 0.029 14.2 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 Cohesin domain Cob_adeno_trans PF01923.13 EEA05382.1 - 0.11 12.2 0.2 0.72 9.6 0.0 2.4 4 0 0 4 4 4 0 Cobalamin adenosyltransferase zf-AD PF07776.10 EEA05382.1 - 0.15 12.0 2.3 1.8 8.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) B3_4 PF03483.12 EEA05383.1 - 4.1e-19 68.7 0.0 8.3e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EEA05383.1 - 5.7e-19 67.7 0.0 2.4e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain eIF-1a PF01176.14 EEA05384.1 - 3.5e-30 103.2 0.1 5.8e-30 102.5 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PWI PF01480.12 EEA05385.1 - 9.5e-20 70.4 0.9 9.5e-20 70.4 0.6 2.1 2 0 0 2 2 2 1 PWI domain CBM_14 PF01607.19 EEA05386.1 - 0.051 13.5 44.1 0.71 9.8 0.1 9.4 6 1 2 8 8 8 0 Chitin binding Peritrophin-A domain DUF2259 PF10016.4 EEA05386.1 - 0.068 12.8 4.2 1.2 8.8 0.0 3.9 5 0 0 5 5 5 0 Predicted secreted protein (DUF2259) Racemase_4 PF13615.1 EEA05387.1 - 6.6e-27 93.7 0.1 1.6e-26 92.5 0.1 1.7 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 EEA05387.1 - 1.6e-06 27.7 0.0 4.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor RRM_1 PF00076.17 EEA05388.1 - 5.9e-26 89.9 0.1 6.6e-16 57.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05388.1 - 1.7e-15 56.7 0.0 7.3e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05388.1 - 1.9e-15 56.4 0.0 1.9e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA05388.1 - 0.069 13.0 0.0 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif NUC173 PF08161.7 EEA05389.1 - 1.6e-26 92.9 0.9 2.8e-25 88.8 0.1 2.9 2 0 0 2 2 2 1 NUC173 domain DUF2435 PF10363.4 EEA05389.1 - 0.00091 19.0 5.2 0.0066 16.3 0.0 4.7 5 1 0 5 5 5 1 Protein of unknown function (DUF2435) Brix PF04427.13 EEA05390.1 - 3.7e-44 150.6 0.1 7.4e-44 149.6 0.1 1.5 1 0 0 1 1 1 1 Brix domain NIF PF03031.13 EEA05391.1 - 2.2e-29 102.1 0.0 3.3e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTH2 PF01981.11 EEA05392.1 - 8e-11 41.6 0.0 8.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RFC1 PF08519.7 EEA05392.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain YolD PF08863.5 EEA05392.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 YolD-like protein PrmA PF06325.8 EEA05393.1 - 1.9e-10 40.3 0.0 3.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EEA05393.1 - 6.3e-10 38.8 0.4 2.3e-09 37.0 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA05393.1 - 3.6e-09 36.6 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA05393.1 - 1.3e-07 32.2 0.0 3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA05393.1 - 2.1e-06 28.1 0.0 5.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA05393.1 - 4.1e-06 26.2 0.0 8.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEA05393.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEA05393.1 - 0.00019 20.2 0.0 0.00032 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EEA05393.1 - 0.0011 19.3 0.0 0.0036 17.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EEA05393.1 - 0.0016 17.6 0.0 0.0039 16.3 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EEA05393.1 - 0.012 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 EEA05393.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EEA05393.1 - 0.02 14.0 0.0 0.056 12.5 0.0 1.8 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EEA05393.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EEA05393.1 - 0.065 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EEA05393.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EEA05393.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF3458 PF11940.3 EEA05394.1 - 1.2e-85 287.6 0.0 1.6e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EEA05394.1 - 9.6e-56 189.5 0.0 1.4e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EEA05394.1 - 4.8e-13 49.2 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3458 PF11940.3 EEA05395.1 - 3.1e-85 286.2 0.0 4.1e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EEA05395.1 - 1.6e-52 178.9 0.0 2.3e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EEA05395.1 - 6.9e-13 48.7 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily YL1 PF05764.8 EEA05396.1 - 6.3e-30 104.5 38.0 6.3e-30 104.5 26.4 2.2 1 1 1 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EEA05396.1 - 9.5e-11 41.0 1.4 1.1e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PAN_4 PF14295.1 EEA05398.1 - 1.9e-07 30.6 18.7 9e-07 28.5 0.2 4.3 3 2 0 3 3 3 2 PAN domain PAN_1 PF00024.21 EEA05398.1 - 0.0015 18.2 3.8 0.0015 18.2 2.6 3.7 2 2 1 3 3 3 2 PAN domain TSP_1 PF00090.14 EEA05398.1 - 0.0097 16.0 4.2 0.0097 16.0 2.9 5.0 4 2 1 5 5 5 2 Thrombospondin type 1 domain ThiF PF00899.16 EEA05399.1 - 1.9e-06 27.7 0.4 1.1e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 ThiF family Anticodon_1 PF08264.8 EEA05399.1 - 0.36 10.5 4.6 4.1 7.1 0.5 2.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA RNA_pol_Rpb2_6 PF00562.23 EEA05400.1 - 2.3e-118 395.2 0.0 3.7e-118 394.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA05400.1 - 1.7e-46 157.7 1.4 3.3e-46 156.7 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EEA05400.1 - 1.3e-28 99.0 0.0 3.6e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEA05400.1 - 1e-24 86.1 0.0 2.2e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 EEA05400.1 - 5.8e-20 71.5 2.6 3.4e-12 46.1 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EEA05400.1 - 5.8e-20 70.8 0.0 1.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEA05400.1 - 5.3e-12 45.5 1.0 2e-11 43.6 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 DEAD PF00270.24 EEA05402.1 - 2.9e-34 117.9 0.1 9.7e-34 116.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA05402.1 - 6.9e-23 80.3 0.0 1.8e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEA05402.1 - 0.00059 19.9 3.2 0.0066 16.5 0.0 3.0 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 EEA05402.1 - 0.0035 17.2 1.9 0.41 10.4 0.0 3.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit FokI_N PF02981.10 EEA05402.1 - 0.01 15.4 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain CMS1 PF14617.1 EEA05402.1 - 0.014 14.5 2.8 0.09 11.8 0.0 3.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF4345 PF14248.1 EEA05402.1 - 0.28 10.6 0.0 0.54 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF2207 PF09972.4 EEA05403.1 - 0.027 13.0 0.4 0.026 13.1 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GpcrRhopsn4 PF10192.4 EEA05403.1 - 0.034 13.3 5.5 0.045 12.9 3.8 1.0 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain SPC12 PF06645.8 EEA05403.1 - 0.23 11.2 1.8 0.38 10.5 1.3 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3784 PF12650.2 EEA05403.1 - 0.36 10.8 5.8 0.48 10.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF4526 PF15029.1 EEA05403.1 - 0.51 9.8 1.8 0.77 9.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) YfzA PF14118.1 EEA05403.1 - 0.86 9.7 5.5 0.85 9.7 0.4 2.1 1 1 1 2 2 2 0 YfzA-like protein DUF3953 PF13129.1 EEA05403.1 - 1 9.0 6.3 1.6 8.3 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) DUF3278 PF11683.3 EEA05403.1 - 1.3 9.0 5.5 1.8 8.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) TBP PF00352.16 EEA05405.1 - 2.4e-24 84.4 1.1 3.3e-10 39.2 0.0 3.1 2 1 1 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) UQ_con PF00179.21 EEA05406.1 - 5.6e-28 97.1 0.1 7.3e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA05406.1 - 0.0036 17.1 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UCH PF00443.24 EEA05407.1 - 1.9e-38 132.1 11.2 1.9e-38 132.1 7.8 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA05407.1 - 3.2e-11 43.2 15.1 4.2e-08 32.9 10.5 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EXOSC1 PF10447.4 EEA05408.1 - 0.00016 21.5 0.0 0.0049 16.8 0.0 2.3 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 DUF2318 PF10080.4 EEA05408.1 - 0.00068 19.3 0.3 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) ECR1_N PF14382.1 EEA05408.1 - 0.003 16.8 0.1 0.003 16.8 0.0 2.2 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Auto_anti-p27 PF06677.7 EEA05408.1 - 0.08 12.7 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MOZ_SAS PF01853.13 EEA05410.1 - 4.4e-70 234.7 4.4 4.1e-67 225.0 0.9 2.5 3 0 0 3 3 3 2 MOZ/SAS family Tudor-knot PF11717.3 EEA05410.1 - 4.6e-10 39.0 1.0 1.1e-09 37.7 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EEA05410.1 - 0.021 15.1 2.2 0.055 13.8 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Acetyltransf_7 PF13508.1 EEA05410.1 - 0.036 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA05410.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.1 EEA05410.1 - 0.4 11.1 2.6 1.2 9.6 1.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger MS_channel PF00924.13 EEA05412.1 - 1.3e-16 60.5 0.5 2.7e-16 59.5 0.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel Fumble PF03630.9 EEA05413.1 - 1.8e-23 82.9 1.8 2e-22 79.5 1.2 2.3 1 1 0 1 1 1 1 Fumble SNAPc_SNAP43 PF09808.4 EEA05414.1 - 1.9e-08 34.2 5.9 9.9e-07 28.6 4.0 3.1 1 1 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Metallophos PF00149.23 EEA05415.1 - 3e-07 30.0 5.7 6.1e-07 29.0 2.5 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase VMA21 PF09446.5 EEA05416.1 - 5.9e-07 29.3 8.9 8.4e-07 28.8 6.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF3671 PF12420.3 EEA05416.1 - 1.5 8.8 8.6 2.2 8.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2207 PF09972.4 EEA05416.1 - 1.6 7.2 3.5 1.9 6.9 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF843 PF05814.6 EEA05416.1 - 7.4 6.4 7.3 0.58 9.9 1.0 1.9 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) RNA_pol_A_bac PF01000.21 EEA05417.1 - 3.8e-25 88.2 0.2 2.1e-24 85.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEA05417.1 - 1.9e-19 68.5 0.0 2.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 EEA05417.1 - 0.0015 18.7 2.5 0.0015 18.7 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EEA05417.1 - 0.0026 18.1 1.0 0.0026 18.1 0.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEA05417.1 - 0.0066 16.2 1.0 0.0066 16.2 0.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EEA05417.1 - 4.9 6.9 8.3 1.9 8.2 0.4 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain SWIM PF04434.12 EEA05418.1 - 0.012 15.1 1.1 0.033 13.6 0.7 1.8 1 0 0 1 1 1 0 SWIM zinc finger RNase_PH PF01138.16 EEA05421.1 - 5.3e-17 62.3 0.0 8.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEA05421.1 - 0.0011 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 tRNA-synt_2 PF00152.15 EEA05422.1 - 5.9e-67 225.8 0.0 3.4e-57 193.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA05422.1 - 1.5e-07 31.1 0.3 3.5e-07 29.9 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEA05422.1 - 0.0007 18.8 0.1 0.0036 16.5 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) MAAL_N PF05034.8 EEA05422.1 - 0.015 15.1 0.1 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus vATP-synt_E PF01991.13 EEA05423.1 - 5.7e-51 172.6 4.6 6.6e-51 172.4 3.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit MutS_V PF00488.16 EEA05424.1 - 8.1e-85 283.9 0.4 1.4e-84 283.1 0.1 1.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EEA05424.1 - 2.8e-32 112.1 0.2 1.8e-31 109.5 0.1 2.4 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EEA05424.1 - 9.1e-32 109.4 0.0 4.4e-31 107.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EEA05424.1 - 5e-06 26.6 0.0 1.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEA05424.1 - 0.046 13.8 2.2 0.14 12.2 1.5 1.8 1 0 0 1 1 1 0 MutS family domain IV DAO PF01266.19 EEA05425.1 - 4.4e-17 62.0 0.0 6.3e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 EEA05425.1 - 2.9e-15 55.4 0.0 6e-15 54.3 0.0 1.4 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 EEA05425.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1837 PF08878.6 EEA05425.1 - 0.042 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) IPP-2 PF04979.9 EEA05426.1 - 1.8e-15 57.3 1.8 1e-14 54.8 1.2 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Sin3_corepress PF08295.7 EEA05426.1 - 0.05 13.3 0.3 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Sin3 family co-repressor Ribosomal_L6 PF00347.18 EEA05427.1 - 6.3e-30 103.5 2.4 6.7e-14 52.1 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 gpW PF02831.10 EEA05429.1 - 0.14 11.7 0.3 0.36 10.4 0.2 1.7 1 0 0 1 1 1 0 gpW Ribosomal_L7Ae PF01248.21 EEA05430.1 - 7.1e-21 73.5 0.8 1.3e-20 72.6 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SMAP PF15477.1 EEA05430.1 - 0.13 12.5 4.2 3.2 8.0 0.2 3.2 3 0 0 3 3 3 0 Small acidic protein family Ribosomal_L18p PF00861.17 EEA05431.1 - 8.2e-38 129.2 0.8 1.2e-37 128.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EEA05431.1 - 6.7e-33 113.1 4.5 6.7e-33 113.1 3.1 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 EEA05431.1 - 0.02 15.1 0.2 0.056 13.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1476) ATP_sub_h PF10775.4 EEA05431.1 - 0.095 12.4 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 ATP synthase complex subunit h DnaJ PF00226.26 EEA05432.1 - 1.5e-14 53.4 0.5 1.5e-14 53.4 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain FlgM PF04316.8 EEA05432.1 - 0.67 9.9 3.9 2 8.4 0.2 2.9 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM Beta-Casp PF10996.3 EEA05433.1 - 1.5e-31 108.9 0.0 3.5e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EEA05433.1 - 4.5e-14 52.5 0.1 7.8e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 EEA05433.1 - 4.1e-12 45.9 0.1 7e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 EEA05433.1 - 4.9e-11 42.5 0.2 2.4e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EEA05433.1 - 5e-11 42.2 0.0 1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EEA05433.1 - 0.00093 18.9 0.0 0.0048 16.6 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Hist_deacetyl PF00850.14 EEA05434.1 - 4.5e-67 226.5 0.0 6.9e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.1 EEA05434.1 - 4.6e-13 49.2 1.5 0.00042 20.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA05434.1 - 5.2e-11 42.7 0.1 2e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA05434.1 - 7.3e-09 35.6 0.2 3.1e-06 27.2 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA05434.1 - 2.2e-08 33.5 0.1 0.2 12.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 EEA05434.1 - 2.7e-08 33.2 3.0 0.0075 16.0 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat NAAA-beta PF15508.1 EEA05435.1 - 0.0094 16.2 1.8 47 4.4 0.0 4.3 2 1 1 4 4 4 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Myosin_tail_1 PF01576.14 EEA05435.1 - 0.041 11.6 52.4 0.098 10.3 36.3 1.8 1 1 0 1 1 1 0 Myosin tail EF-hand_8 PF13833.1 EEA05436.1 - 7.1e-12 44.7 0.5 5.2e-08 32.3 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EEA05436.1 - 1.2e-09 38.1 1.3 8.1e-09 35.5 0.1 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA05436.1 - 3.5e-08 32.1 0.3 0.017 14.4 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EEA05436.1 - 7.3e-08 31.6 1.8 0.019 14.8 0.0 4.0 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EEA05436.1 - 0.0021 17.3 5.0 0.41 10.0 0.0 3.9 4 1 1 5 5 5 2 EF hand EF-hand_9 PF14658.1 EEA05436.1 - 0.0047 16.8 0.4 0.011 15.6 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain Ten1_2 PF15490.1 EEA05437.1 - 2.8e-13 49.4 0.2 3.5e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit tRNA_anti-codon PF01336.20 EEA05437.1 - 0.0035 17.1 0.2 0.0065 16.3 0.2 1.4 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PseudoU_synth_1 PF01416.15 EEA05438.1 - 2.7e-25 88.8 0.1 4.6e-11 43.0 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ycf1 PF05758.7 EEA05439.1 - 2.3 5.8 39.4 5.4 4.6 27.3 1.5 1 1 0 1 1 1 0 Ycf1 DUF3530 PF12048.3 EEA05439.1 - 3.5 6.5 9.9 6.5 5.6 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BTV_NS2 PF04514.7 EEA05439.1 - 4.1 6.1 32.8 7.7 5.2 22.7 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spore_coat_CotO PF14153.1 EEA05439.1 - 8.3 5.8 40.8 7.9e+02 -0.7 28.3 2.2 1 1 0 1 1 1 0 Spore coat protein CotO EF-hand_7 PF13499.1 EEA05440.1 - 0.0061 16.6 2.7 0.058 13.5 1.9 2.4 1 1 0 1 1 1 1 EF-hand domain pair GCN5L1 PF06320.8 EEA05440.1 - 0.036 13.8 0.7 0.069 12.9 0.1 1.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) EF-hand_1 PF00036.27 EEA05440.1 - 2.7 7.5 7.9 6.5 6.3 0.0 4.0 5 0 0 5 5 5 0 EF hand PC_rep PF01851.17 EEA05445.1 - 1.1e-16 60.0 10.5 2.3e-06 27.5 0.3 6.8 6 0 0 6 6 6 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEA05445.1 - 2.2e-07 31.0 0.7 0.026 14.8 0.1 4.9 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEA05445.1 - 0.026 15.0 0.0 11 6.6 0.0 3.4 2 0 0 2 2 2 0 HEAT-like repeat UQ_con PF00179.21 EEA05446.1 - 6.9e-17 61.1 0.0 7.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA05446.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Abhydrolase_6 PF12697.2 EEA05447.1 - 2.3e-21 76.7 0.0 3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA05447.1 - 3.1e-13 49.7 0.0 5.8e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA05447.1 - 1.8e-11 44.0 0.0 1.6e-10 40.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA05447.1 - 2.5e-07 30.4 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EEA05447.1 - 0.00019 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EEA05447.1 - 0.0045 15.5 0.0 0.37 9.2 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) UPF0227 PF05728.7 EEA05447.1 - 0.011 15.4 0.0 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 EEA05447.1 - 0.039 13.1 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Patatin PF01734.17 EEA05447.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase DUF258 PF03193.11 EEA05447.1 - 0.12 11.6 0.2 0.24 10.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Abhydrolase_6 PF12697.2 EEA05448.1 - 1.2e-23 84.1 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA05448.1 - 3.3e-13 49.7 0.0 1.7e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA05448.1 - 5.7e-13 48.8 0.0 4.4e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA05448.1 - 0.00092 19.0 0.4 0.0024 17.7 0.1 1.8 2 0 0 2 2 2 1 Putative lysophospholipase BAAT_C PF08840.6 EEA05448.1 - 0.0012 18.6 0.0 0.0082 15.8 0.0 2.2 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 EEA05448.1 - 0.0093 15.5 0.1 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ndr PF03096.9 EEA05448.1 - 0.017 13.6 0.0 0.032 12.7 0.0 1.4 1 0 0 1 1 1 0 Ndr family AXE1 PF05448.7 EEA05448.1 - 0.069 11.6 0.0 0.31 9.5 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 EEA05448.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EEA05448.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase RFC1 PF08519.7 EEA05449.1 - 2.8e-37 127.8 2.2 2.8e-37 127.8 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EEA05449.1 - 1.3e-13 50.9 0.0 1e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEA05449.1 - 8.8e-13 48.6 2.7 2.7e-11 43.8 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EEA05449.1 - 4.4e-10 39.3 0.5 1.9e-09 37.2 0.3 2.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 EEA05449.1 - 2.6e-06 28.2 0.2 1.5e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA05449.1 - 1.7e-05 24.9 0.1 9.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.2 EEA05449.1 - 3.9e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Rad17 PF03215.10 EEA05449.1 - 5.7e-05 22.0 10.3 0.00072 18.3 0.1 3.9 2 2 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EEA05449.1 - 6.2e-05 23.3 0.1 6.2e-05 23.3 0.0 3.4 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EEA05449.1 - 0.00013 21.1 0.0 0.00049 19.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEA05449.1 - 0.0013 18.6 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA05449.1 - 0.003 17.5 0.1 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA05449.1 - 0.0034 17.1 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA05449.1 - 0.0043 16.6 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA05449.1 - 0.0045 16.7 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA05449.1 - 0.0052 15.8 0.0 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EEA05449.1 - 0.0078 16.1 1.5 0.024 14.5 0.0 2.7 3 1 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EEA05449.1 - 0.032 13.9 0.1 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 EEA05449.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasom_PSMB PF10508.4 EEA05451.1 - 6.4e-75 252.3 9.5 8.4e-75 251.9 6.6 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF3639 PF12341.3 EEA05452.1 - 5.4e-09 35.8 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) LEDGF PF11467.3 EEA05453.1 - 0.094 12.4 3.6 0.38 10.4 1.0 2.6 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Myosin_head PF00063.16 EEA05455.1 - 1.4e-155 519.1 12.8 1.7e-155 518.8 6.5 2.6 2 1 0 2 2 2 1 Myosin head (motor domain) Zeta_toxin PF06414.7 EEA05455.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EEA05455.1 - 0.033 14.3 0.0 0.17 12.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EEA05455.1 - 0.058 12.7 2.5 3.3 6.9 0.0 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EEA05455.1 - 0.24 12.1 2.0 1.6 9.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.1 EEA05455.1 - 0.36 10.3 0.0 0.69 9.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEA05455.1 - 0.45 10.3 0.0 0.86 9.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L23 PF00276.15 EEA05456.1 - 4.2e-17 61.8 2.1 4.2e-17 61.8 1.5 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EEA05456.1 - 4e-09 36.3 8.5 4e-09 36.3 5.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain DUF916 PF06030.7 EEA05456.1 - 0.014 15.2 1.2 0.043 13.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) DUF1727 PF08353.5 EEA05456.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) Mei5 PF10376.4 EEA05457.1 - 0.0055 16.2 5.8 0.0063 16.0 4.0 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Cas_APE2256 PF09651.5 EEA05457.1 - 0.045 13.4 0.3 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_APE2256) TPM PF04536.9 EEA05458.1 - 8.6e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase DUF1191 PF06697.7 EEA05458.1 - 0.16 10.7 0.0 0.44 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Prefoldin PF02996.12 EEA05459.1 - 5.4e-18 64.7 0.7 5.4e-18 64.7 0.5 1.9 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.1 EEA05459.1 - 0.00013 21.6 0.6 0.022 14.5 0.1 2.6 2 1 0 2 2 2 2 Prefoldin subunit Tropomyosin PF00261.15 EEA05459.1 - 1.3 8.0 7.2 0.32 10.0 0.7 2.3 2 0 0 2 2 2 0 Tropomyosin DUF948 PF06103.6 EEA05459.1 - 4.4 7.2 5.3 23 4.9 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 EEA05459.1 - 6.6 7.2 9.8 0.68 10.3 0.6 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 EEA05459.1 - 6.9 6.4 14.0 1.9 8.2 0.7 3.1 3 1 0 3 3 3 0 Prefoldin subunit Pkinase PF00069.20 EEA05460.1 - 1.1e-66 224.7 0.0 2e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 EEA05460.1 - 7.8e-60 198.6 3.4 1.8e-17 62.9 0.0 4.8 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 EEA05460.1 - 1.2e-28 99.8 0.0 2.1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05460.1 - 2.4e-09 36.5 0.0 5.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA05460.1 - 0.0055 16.4 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA05460.1 - 0.033 13.0 0.0 0.087 11.6 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EEA05460.1 - 0.086 11.8 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.19 EEA05463.1 - 0.0029 17.2 22.6 0.0041 16.7 0.8 4.9 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA05463.1 - 0.74 9.9 23.6 1.2 9.2 0.4 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type tRNA-synt_1c PF00749.16 EEA05464.1 - 1.4e-104 349.1 0.0 1.7e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEA05464.1 - 9e-35 119.8 0.0 1.9e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DEAD PF00270.24 EEA05465.1 - 1.4e-44 151.5 0.1 5.7e-44 149.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA05465.1 - 7.5e-20 70.5 0.0 2.9e-19 68.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AP2 PF00847.15 EEA05466.1 - 8.4e-11 41.8 2.9 1.6e-10 40.9 2.0 1.5 1 0 0 1 1 1 1 AP2 domain DUF2040 PF09745.4 EEA05468.1 - 4e-15 55.7 7.9 4e-15 55.7 5.5 2.1 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) TAF8_C PF10406.4 EEA05468.1 - 9.1 6.4 6.4 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term AAA PF00004.24 EEA05469.1 - 4.3e-42 143.4 0.0 7.9e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA05469.1 - 1.9e-06 28.0 0.1 0.0001 22.3 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EEA05469.1 - 2e-06 27.8 0.0 7.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEA05469.1 - 5.5e-06 26.5 0.0 0.0013 18.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA05469.1 - 7.8e-06 25.6 0.1 0.0001 22.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEA05469.1 - 3.4e-05 23.0 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEA05469.1 - 0.00055 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEA05469.1 - 0.001 17.8 0.1 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EEA05469.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 EEA05469.1 - 0.0019 17.6 0.0 0.007 15.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EEA05469.1 - 0.0026 16.9 0.1 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEA05469.1 - 0.0029 16.7 0.0 0.0069 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EEA05469.1 - 0.003 17.8 0.1 0.05 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA05469.1 - 0.0031 17.2 0.0 0.0084 15.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEA05469.1 - 0.0041 17.9 0.6 0.024 15.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA05469.1 - 0.0041 16.5 0.2 0.031 13.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain DUF4200 PF13863.1 EEA05469.1 - 0.0049 16.8 6.1 0.012 15.5 4.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_3 PF07726.6 EEA05469.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA05469.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEA05469.1 - 0.0081 15.1 0.0 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EEA05469.1 - 0.0088 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.1 EEA05469.1 - 0.0098 15.7 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EEA05469.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA05469.1 - 0.015 15.2 0.1 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EEA05469.1 - 0.016 14.5 0.2 2.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase KaiC PF06745.8 EEA05469.1 - 0.017 14.2 0.6 0.079 12.0 0.0 2.2 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 EEA05469.1 - 0.022 14.4 0.1 0.16 11.6 0.0 2.4 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 EEA05469.1 - 0.026 14.1 1.0 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EEA05469.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EEA05469.1 - 0.031 14.3 0.0 0.08 12.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EEA05469.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EEA05469.1 - 0.096 11.6 0.4 0.94 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EEA05469.1 - 0.13 12.5 4.6 4.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EEA05469.1 - 0.17 9.6 0.2 0.23 9.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EEA05469.1 - 0.6 9.6 3.0 1.1 8.7 2.1 1.4 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EEA05469.1 - 1.1 9.3 5.9 2.7 8.0 3.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Coat_X PF07552.6 EEA05470.1 - 2.3 8.0 10.0 0.14 11.9 1.7 2.8 3 0 0 3 3 3 0 Spore Coat Protein X and V domain Coatomer_WDAD PF04053.9 EEA05471.1 - 8.8e-59 199.4 15.5 3.4e-53 181.0 3.1 3.0 3 1 0 3 3 3 2 Coatomer WD associated region WD40 PF00400.27 EEA05471.1 - 9.3e-49 161.6 18.5 1.4e-10 40.6 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat COPI_C PF06957.6 EEA05471.1 - 1.3e-46 158.9 0.1 2.5e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TF_Zn_Ribbon PF08271.7 EEA05471.1 - 0.27 10.5 2.6 0.65 9.3 1.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EEA05471.1 - 0.88 8.8 3.3 2.1 7.6 2.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DNA_pol_E_B PF04042.11 EEA05472.1 - 1e-30 106.5 1.6 1.7e-30 105.8 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2248 PF10005.4 EEA05472.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) TFIIB PF00382.14 EEA05473.1 - 2.3e-12 46.5 0.6 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEA05473.1 - 1.2e-10 40.5 1.6 2.6e-10 39.4 1.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Hs1pro-1_N PF07231.7 EEA05473.1 - 0.027 14.0 1.7 0.062 12.8 0.0 2.3 2 1 1 3 3 3 0 Hs1pro-1 N-terminus DUF1936 PF09151.5 EEA05473.1 - 0.042 13.3 0.3 9 5.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1936) cobW PF02492.14 EEA05474.1 - 6.3e-37 126.7 5.8 2.5e-36 124.7 4.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEA05474.1 - 2.8e-05 23.7 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain T2SE PF00437.15 EEA05474.1 - 0.00043 19.2 1.8 0.0014 17.5 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EEA05474.1 - 0.00086 19.0 0.1 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA05474.1 - 0.0011 19.0 0.1 0.0036 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EEA05474.1 - 0.0019 17.8 0.4 0.0044 16.7 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 EEA05474.1 - 0.0023 17.4 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EEA05474.1 - 0.0034 17.7 1.3 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA05474.1 - 0.0045 16.7 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EEA05474.1 - 0.0046 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EEA05474.1 - 0.0054 16.4 1.1 0.011 15.4 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EEA05474.1 - 0.0078 16.1 3.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EEA05474.1 - 0.019 14.5 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EEA05474.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EEA05474.1 - 0.07 11.8 0.1 6.9 5.3 0.1 2.2 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 EEA05474.1 - 0.094 11.3 0.1 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EEA05474.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEA05474.1 - 0.13 11.9 3.0 0.13 11.9 0.9 1.9 2 0 0 2 2 2 0 NTPase CesA PF11439.3 EEA05474.1 - 0.93 9.4 6.8 12 5.9 0.0 3.7 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA U3_assoc_6 PF08640.6 EEA05475.1 - 1.4e-25 88.8 2.4 2.8e-25 87.8 0.6 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_19 PF14559.1 EEA05475.1 - 0.017 15.4 0.0 0.42 10.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_J PF04911.7 EEA05475.1 - 0.2 11.1 4.0 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 ATP synthase j chain Pep3_Vps18 PF05131.9 EEA05476.1 - 6.6e-07 28.8 1.2 0.0023 17.3 0.2 2.5 2 0 0 2 2 2 2 Pep3/Vps18/deep orange family UDPG_MGDP_dh_N PF03721.9 EEA05477.1 - 1.2e-49 168.2 0.0 5.4e-49 166.0 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EEA05477.1 - 1.5e-30 105.4 0.0 3e-28 98.0 0.0 3.0 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EEA05477.1 - 2.1e-29 101.5 0.0 5.9e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EEA05477.1 - 0.016 15.0 0.0 0.071 12.9 0.0 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EEA05477.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase zf-rbx1 PF12678.2 EEA05478.1 - 1.3e-35 121.3 13.8 1.8e-35 120.9 9.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEA05478.1 - 9.2e-19 67.0 10.3 1.3e-18 66.5 7.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EEA05478.1 - 5.4e-08 32.5 13.0 4.4e-07 29.6 9.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA05478.1 - 0.00091 18.8 10.8 0.086 12.5 7.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA05478.1 - 0.0012 18.5 12.1 0.0066 16.0 8.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05478.1 - 0.012 15.5 12.9 0.66 10.0 9.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA05478.1 - 0.087 12.5 11.7 0.52 10.0 8.1 2.2 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 EEA05478.1 - 0.15 12.0 9.5 1.7 8.6 7.0 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EEA05478.1 - 0.49 10.4 10.1 2.5 8.1 7.0 2.0 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEA05478.1 - 0.56 10.3 10.6 79 3.5 7.4 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 EEA05478.1 - 5.2 7.0 8.0 0.55 10.1 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.4 EEA05479.1 - 2.7e-06 27.2 4.6 4.3e-06 26.5 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DUF2361 PF10153.4 EEA05479.1 - 0.088 12.9 0.5 0.12 12.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Adap_comp_sub PF00928.16 EEA05480.1 - 1.5e-59 201.2 4.1 2.1e-59 200.7 2.8 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEA05480.1 - 4.4e-05 23.2 3.7 0.00011 21.8 2.5 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HpaB PF03241.8 EEA05480.1 - 0.22 10.3 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Lung_7-TM_R PF06814.8 EEA05481.1 - 0.012 14.5 22.1 0.031 13.2 15.3 1.6 1 1 0 1 1 1 0 Lung seven transmembrane receptor DicB PF05358.6 EEA05481.1 - 0.025 14.0 0.4 0.098 12.1 0.3 2.0 1 0 0 1 1 1 0 DicB protein Invasin_D3 PF09134.5 EEA05481.1 - 0.044 13.6 0.5 0.044 13.6 0.3 2.3 3 0 0 3 3 3 0 Invasin, domain 3 EF-hand_7 PF13499.1 EEA05483.1 - 4.5e-09 36.3 0.5 4.6e-05 23.4 0.3 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA05483.1 - 2.6e-08 33.0 0.1 0.0081 15.9 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EEA05483.1 - 7.2e-07 28.0 0.1 0.0083 15.3 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EEA05483.1 - 2.1e-05 24.3 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EEA05483.1 - 0.00098 18.6 0.5 3.5 7.3 0.1 3.5 3 1 0 3 3 3 1 EF-hand domain pair DREV PF05219.7 EEA05483.1 - 0.042 12.7 0.1 0.11 11.2 0.0 1.8 1 1 0 1 1 1 0 DREV methyltransferase SelB-wing_1 PF09105.5 EEA05483.1 - 0.054 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix EF-hand_5 PF13202.1 EEA05483.1 - 0.083 12.2 1.1 17 4.9 0.1 3.4 3 0 0 3 3 3 0 EF hand Rad21_Rec8_N PF04825.8 EEA05486.1 - 3.3e-09 36.6 2.4 4.9e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEA05486.1 - 2.8e-06 26.3 0.0 5.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EEA05486.1 - 0.0072 15.9 0.2 0.0072 15.9 0.1 2.2 2 0 0 2 2 2 1 ScpA/B protein tRNA-synt_2b PF00587.20 EEA05487.1 - 2.1e-58 196.7 0.0 3.7e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA05487.1 - 4.2e-20 71.4 0.0 9.2e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ras PF00071.17 EEA05488.1 - 1e-56 190.7 0.2 1.2e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA05488.1 - 3.8e-20 72.5 0.0 5.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA05488.1 - 2.2e-14 53.0 0.1 2.9e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA05488.1 - 2.1e-06 27.3 0.1 7.9e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA05488.1 - 3.2e-05 23.8 0.1 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEA05488.1 - 0.0003 20.3 0.3 0.0046 16.4 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EEA05488.1 - 0.0011 18.5 0.0 0.37 10.3 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 EEA05488.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgK PF03308.11 EEA05488.1 - 0.02 13.6 0.2 0.98 8.1 0.1 2.1 1 1 1 2 2 2 0 ArgK protein AAA_22 PF13401.1 EEA05488.1 - 0.027 14.5 0.1 0.069 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEA05488.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EEA05488.1 - 0.057 12.6 0.2 0.36 10.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 EEA05488.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EEA05488.1 - 0.088 12.7 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EEA05488.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain IL8 PF00048.15 EEA05489.1 - 0.021 14.7 1.7 0.077 12.9 0.1 2.6 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Gar1 PF04410.9 EEA05490.1 - 3.5e-18 65.5 0.2 3.5e-18 65.5 0.2 2.7 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Fumerase PF05681.9 EEA05490.1 - 0.079 12.0 0.4 0.13 11.2 0.3 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Actin PF00022.14 EEA05491.1 - 6.3e-36 123.6 0.0 1.1e-35 122.8 0.0 1.3 1 1 0 1 1 1 1 Actin Longin PF13774.1 EEA05491.1 - 0.055 13.0 0.1 0.58 9.7 0.0 2.4 2 0 0 2 2 2 0 Regulated-SNARE-like domain GAS PF13851.1 EEA05491.1 - 3.2 6.9 5.7 13 4.9 0.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sec1 PF00995.18 EEA05492.1 - 3.6e-82 276.8 21.1 7.9e-82 275.6 14.6 1.5 1 1 0 1 1 1 1 Sec1 family CENP-Q PF13094.1 EEA05493.1 - 0.00082 19.4 0.4 0.00082 19.4 0.3 3.7 2 2 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit OSCP PF00213.13 EEA05494.1 - 1.5e-33 116.0 1.1 1.8e-33 115.8 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF816 PF05674.7 EEA05494.1 - 0.0096 15.6 4.7 0.018 14.7 3.3 1.5 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) CRC_subunit PF08624.5 EEA05494.1 - 0.041 13.7 0.3 0.14 12.1 0.1 1.8 1 1 1 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit Spore_GerAC PF05504.6 EEA05494.1 - 0.042 13.6 2.8 0.053 13.3 2.0 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal NadA PF02445.11 EEA05494.1 - 0.048 12.4 0.3 0.064 12.0 0.2 1.1 1 0 0 1 1 1 0 Quinolinate synthetase A protein Arc_PepC_II PF06847.6 EEA05494.1 - 0.073 13.5 0.1 2 8.8 0.0 2.4 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Wzz PF02706.10 EEA05494.1 - 0.075 12.8 1.4 0.12 12.2 1.0 1.2 1 0 0 1 1 1 0 Chain length determinant protein Nrap PF03813.9 EEA05495.1 - 3.5e-93 312.8 14.8 1.8e-82 277.4 6.3 2.9 1 1 1 2 2 2 2 Nrap protein ER_lumen_recept PF00810.13 EEA05496.1 - 3.8e-51 173.4 12.8 6.1e-51 172.7 8.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EEA05496.1 - 0.027 14.0 1.6 0.027 14.0 1.1 4.3 3 2 1 4 4 4 0 PQ loop repeat YycC PF14174.1 EEA05496.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 YycC-like protein 3HCDH PF00725.17 EEA05497.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain GTP_EFTU PF00009.22 EEA05498.1 - 1.9e-34 118.7 0.1 2.9e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EEA05498.1 - 8.4e-07 28.5 1.3 9.5e-06 25.0 0.0 2.4 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EEA05498.1 - 1.3e-05 25.1 0.1 6.2e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA05498.1 - 0.0033 17.2 0.5 0.58 9.9 0.1 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EEA05498.1 - 0.013 16.0 0.6 0.8 10.2 0.2 2.9 2 1 0 2 2 2 0 Miro-like protein Arf PF00025.16 EEA05498.1 - 0.072 12.3 0.5 0.36 10.0 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF4065 PF13274.1 EEA05498.1 - 0.099 13.3 0.8 0.29 11.8 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) CRAL_TRIO PF00650.15 EEA05499.1 - 0.00065 19.2 0.2 0.0014 18.1 0.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain Pcc1 PF09341.5 EEA05500.1 - 2.4e-09 37.0 0.0 2.6e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF835 PF05763.7 EEA05500.1 - 0.1 12.1 0.3 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF835) CTP_transf_2 PF01467.21 EEA05501.1 - 2.4e-17 63.4 0.9 7.7e-17 61.7 0.6 1.9 1 1 0 1 1 1 1 Cytidylyltransferase Mito_carr PF00153.22 EEA05502.1 - 4.5e-62 205.7 0.5 1.3e-21 76.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CDK2AP PF09806.4 EEA05503.1 - 0.047 13.9 6.7 0.089 13.0 4.6 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2740 PF10872.3 EEA05503.1 - 0.099 12.3 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Pheromone PF08015.6 EEA05503.1 - 1.1 10.1 12.9 3.4 8.5 8.9 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone Aa_trans PF01490.13 EEA05504.1 - 2.1e-25 89.1 37.1 2.5e-25 88.8 25.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1900 PF08954.6 EEA05505.1 - 7e-36 122.7 0.0 1.7e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EEA05505.1 - 2.1e-18 65.4 7.7 2.1e-09 36.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1899 PF08953.6 EEA05505.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) DUF342 PF03961.8 EEA05505.1 - 0.55 8.5 9.3 0.091 11.1 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ribosomal_S27e PF01667.12 EEA05506.1 - 0.0046 16.4 4.9 0.23 11.0 0.2 2.4 2 0 0 2 2 2 2 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EEA05506.1 - 0.067 12.5 1.0 0.067 12.5 0.7 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding RPA_interact_C PF14768.1 EEA05506.1 - 0.12 12.7 9.3 0.13 12.6 0.5 2.8 2 1 0 2 2 2 0 Replication protein A interacting C-terminal FYVE PF01363.16 EEA05506.1 - 0.13 12.2 5.8 0.4 10.6 0.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger DUF2318 PF10080.4 EEA05506.1 - 0.44 10.3 7.6 3.1 7.6 0.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DZR PF12773.2 EEA05506.1 - 2.2 8.1 7.2 1.6e+02 2.2 0.9 2.8 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EEA05506.1 - 2.7 7.7 8.5 0.28 10.8 0.3 2.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 EEA05506.1 - 4.2 7.7 10.1 16 5.8 0.6 3.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-UBR PF02207.15 EEA05506.1 - 4.2 7.1 12.5 3.2 7.5 3.2 2.8 1 1 2 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-DNL PF05180.7 EEA05506.1 - 5.1 6.8 10.5 4.5 7.0 0.5 3.5 3 1 1 4 4 4 0 DNL zinc finger zf-ribbon_3 PF13248.1 EEA05506.1 - 9.6 5.5 11.8 10 5.4 0.9 3.6 1 1 3 4 4 4 0 zinc-ribbon domain HECT PF00632.20 EEA05507.1 - 1.9e-92 309.8 3.4 1.9e-92 309.8 2.4 3.3 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.22 EEA05508.1 - 9.2e-66 217.6 4.8 1.9e-23 81.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_4 PF12146.3 EEA05509.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Pkinase PF00069.20 EEA05510.1 - 4.8e-50 170.1 0.0 1.7e-49 168.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05510.1 - 1.1e-19 70.5 0.0 6.8e-19 67.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05510.1 - 1.5e-05 24.1 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CENP-F_leu_zip PF10473.4 EEA05510.1 - 0.0081 16.0 3.3 0.02 14.7 2.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sbi-IV PF11621.3 EEA05510.1 - 0.039 14.0 1.2 0.11 12.7 0.1 2.3 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI APH PF01636.18 EEA05510.1 - 0.23 11.1 0.0 0.52 10.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family FCP1_C PF09309.5 EEA05510.1 - 0.46 9.7 4.3 0.26 10.5 1.5 1.7 1 1 0 1 1 1 0 FCP1, C-terminal DNA_pol_B_exo1 PF03104.14 EEA05511.1 - 4.7e-50 170.2 4.8 4.7e-50 170.2 3.3 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.7 EEA05511.1 - 1.4e-25 89.6 19.1 3.8e-18 65.2 0.9 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.16 EEA05511.1 - 2.3e-20 72.8 3.9 3.2e-18 65.7 2.3 3.3 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EEA05511.1 - 1.4e-07 31.2 0.1 1.9e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Sec23_trunk PF04811.10 EEA05512.1 - 9.8e-22 77.4 0.0 4.5e-21 75.3 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EEA05512.1 - 1e-17 64.3 1.2 3.9e-17 62.5 0.0 2.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEA05512.1 - 2.9e-13 49.1 6.8 5.2e-13 48.3 2.1 2.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EEA05512.1 - 1.6e-10 40.3 1.7 3.2e-10 39.3 0.1 2.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EEA05512.1 - 0.00031 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1664 PF07889.7 EEA05513.1 - 2.2 8.0 8.7 2.4 7.9 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ly49 PF08391.5 EEA05513.1 - 3.4 7.8 16.9 0.62 10.1 1.8 2.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region HALZ PF02183.13 EEA05513.1 - 3.8 7.2 13.1 0.75 9.5 0.5 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper SlyX PF04102.7 EEA05513.1 - 3.9 7.9 11.1 1.5 9.2 1.8 2.7 2 0 0 2 2 2 0 SlyX DUF3573 PF12097.3 EEA05513.1 - 6.9 5.1 20.5 0.6 8.6 6.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Clathrin PF00637.15 EEA05514.1 - 1.3e-146 482.0 67.0 1.3e-29 102.6 2.9 10.1 10 0 0 10 10 10 9 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EEA05514.1 - 3.1e-12 46.2 0.2 1e-10 41.2 0.0 3.3 3 0 0 3 3 3 1 Clathrin-H-link TPR_11 PF13414.1 EEA05514.1 - 8.8e-05 22.0 0.7 22 4.7 0.0 5.4 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EEA05514.1 - 0.038 13.5 6.6 12 5.6 0.2 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05514.1 - 0.35 10.8 2.7 48 4.2 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 EEA05515.1 - 2.2e-30 101.6 8.6 1.1e-08 33.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA05515.1 - 2.1e-29 101.4 11.7 1.1e-14 54.2 1.5 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EEA05515.1 - 1.6e-24 83.5 6.1 1.8e-08 33.5 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA05515.1 - 1.6e-19 68.2 14.5 2.6e-07 29.6 0.0 4.8 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EEA05515.1 - 1.8e-18 65.9 12.5 1.2e-10 40.8 0.4 3.9 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EEA05515.1 - 5.3e-11 42.2 0.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA05515.1 - 1.2e-05 24.9 3.8 0.058 13.1 0.1 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 EEA05515.1 - 0.00014 21.6 0.1 0.033 13.9 0.0 2.8 2 1 1 3 3 3 1 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 EEA05515.1 - 0.0016 18.4 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 EEA05515.1 - 0.0024 17.4 0.1 0.071 12.6 0.0 2.5 2 1 1 3 3 3 1 Caleosin related protein Nexin_C PF08628.7 EEA05515.1 - 0.02 14.9 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal Toprim_2 PF13155.1 EEA05515.1 - 0.029 14.6 0.3 1 9.7 0.1 2.2 1 1 1 2 2 2 0 Toprim-like DUF2764 PF10962.3 EEA05515.1 - 0.037 13.2 0.4 0.048 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) DUF1257 PF06868.6 EEA05515.1 - 0.057 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DUF4601 PF15373.1 EEA05515.1 - 0.092 11.5 0.1 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Endonuc-dimeris PF09124.5 EEA05515.1 - 0.15 11.7 0.7 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation SMC_N PF02463.14 EEA05517.1 - 3.3e-18 65.7 0.0 7.6e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA05517.1 - 0.0014 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab_N PF02874.18 EEA05517.1 - 0.13 12.4 0.9 0.37 11.0 0.2 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EEA05517.1 - 0.33 10.3 0.1 3.4 7.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain Peptidase_C2 PF00648.16 EEA05519.1 - 1.1e-30 106.6 5.0 1.2e-29 103.3 2.1 2.7 2 1 0 2 2 2 1 Calpain family cysteine protease TP6A_N PF04406.9 EEA05522.1 - 7.9e-15 54.2 0.1 1.6e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase PORR PF11955.3 EEA05523.1 - 3.3e-06 26.1 0.1 0.006 15.3 0.0 2.2 2 0 0 2 2 2 2 Plant organelle RNA recognition domain TPT PF03151.11 EEA05524.1 - 1e-20 73.9 37.3 2.9e-19 69.2 10.7 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EEA05524.1 - 1.1e-10 40.9 37.5 1.9e-10 40.1 26.0 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEA05524.1 - 1.4e-08 34.8 40.8 4.9e-07 29.8 9.9 3.0 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EEA05524.1 - 0.0094 16.1 11.4 0.0094 16.1 7.9 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Acyltransferase PF01553.16 EEA05527.1 - 7.8e-15 54.4 0.2 1.8e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase DNA_primase_lrg PF04104.9 EEA05528.1 - 8.4e-76 254.6 3.2 2.9e-75 252.9 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic and archaeal DNA primase, large subunit SpoIIE PF07228.7 EEA05529.1 - 2.8e-06 27.1 0.0 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEA05529.1 - 1e-05 25.0 0.0 5.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.16 EEA05529.1 - 0.0011 18.4 0.0 0.01 15.2 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Evr1_Alr PF04777.8 EEA05530.1 - 0.00022 21.0 0.4 0.00038 20.3 0.2 1.4 1 0 0 1 1 1 1 Erv1 / Alr family TPT PF03151.11 EEA05531.1 - 3.8e-08 33.1 34.6 1.2e-07 31.5 10.5 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EEA05531.1 - 5.7e-05 23.1 11.2 5.7e-05 23.1 7.8 3.5 1 1 2 4 4 4 3 EamA-like transporter family EmrE PF13536.1 EEA05531.1 - 0.0014 18.7 8.3 0.0014 18.7 5.8 3.1 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EEA05531.1 - 0.24 10.2 29.7 1.8 7.4 20.6 2.1 1 1 0 1 1 1 0 UAA transporter family WD40 PF00400.27 EEA05532.1 - 2.7e-52 172.8 21.1 1.5e-08 34.1 0.0 10.3 10 0 0 10 10 10 9 WD domain, G-beta repeat Nup160 PF11715.3 EEA05532.1 - 2.4e-06 26.0 0.3 0.11 10.5 0.1 4.7 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Sin_N PF04801.8 EEA05533.1 - 7.5e-31 107.4 0.1 1e-15 57.5 0.0 2.6 3 1 0 3 3 3 2 Sin-like protein conserved region RNA_GG_bind PF10258.4 EEA05534.1 - 4.4e-23 80.7 0.0 6.7e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 PHAX RNA-binding domain BLVR PF06375.6 EEA05534.1 - 0.047 13.5 1.4 0.065 13.0 1.0 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) VWD PF00094.20 EEA05534.1 - 0.075 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type D domain Surp PF01805.15 EEA05535.1 - 9.5e-16 57.2 0.5 2.1e-15 56.1 0.3 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 EEA05535.1 - 6.9e-12 44.8 0.0 2.1e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05535.1 - 2.8e-09 36.6 0.0 8.1e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05535.1 - 5.4e-09 35.9 0.0 1.9e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase3 PF13350.1 EEA05536.1 - 2.1e-17 63.8 0.0 2.6e-12 47.2 0.0 2.6 1 1 2 3 3 3 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEA05536.1 - 1.3e-05 25.1 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EEA05536.1 - 0.0016 17.7 1.7 0.028 13.7 0.0 3.2 2 1 2 4 4 4 1 Tyrosine phosphatase family FH2 PF02181.18 EEA05537.1 - 8.6e-43 146.6 14.1 8.6e-43 146.6 9.8 3.0 2 1 0 2 2 2 1 Formin Homology 2 Domain DUF3399 PF11879.3 EEA05537.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) DUF1515 PF07439.6 EEA05539.1 - 0.61 9.9 15.6 0.49 10.2 0.5 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) UCH PF00443.24 EEA05540.1 - 8.1e-56 189.0 1.5 2.3e-55 187.5 1.1 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA05540.1 - 8.7e-28 97.5 5.9 3.7e-23 82.4 0.8 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CotJB PF12652.2 EEA05541.1 - 0.38 10.8 3.1 12 6.0 0.1 2.7 2 0 0 2 2 2 0 CotJB protein zf-C2H2_2 PF12756.2 EEA05542.1 - 1.2e-23 83.1 1.2 1.2e-23 83.1 0.8 3.0 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EEA05542.1 - 0.00021 21.4 3.1 0.085 13.2 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA05542.1 - 0.00032 20.7 2.9 0.0039 17.3 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EEA05542.1 - 0.00058 20.0 5.8 0.011 16.0 0.6 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.2 EEA05542.1 - 0.0064 16.6 2.9 0.81 9.9 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF950 PF06106.6 EEA05542.1 - 0.11 12.5 1.8 0.41 10.7 0.6 2.3 2 1 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) zf-C2H2_6 PF13912.1 EEA05542.1 - 0.12 12.2 0.2 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Pro_isomerase PF00160.16 EEA05543.1 - 2.5e-41 141.4 0.1 3e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCCH PF00642.19 EEA05544.1 - 0.00013 21.5 4.7 0.0002 20.9 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF367 PF04034.8 EEA05545.1 - 3.6e-39 133.2 0.0 6.5e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EEA05545.1 - 1.7e-07 30.6 2.3 2.9e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MFS_1 PF07690.11 EEA05547.1 - 4.2e-43 147.4 35.7 4.4e-39 134.1 16.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3883 PF13020.1 EEA05548.1 - 2.1e-07 30.5 0.0 9.1e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EEA05548.1 - 9.6e-07 28.5 0.0 2.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_E_B PF04042.11 EEA05549.1 - 4.4e-33 114.3 1.0 7e-33 113.6 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B F-box PF00646.28 EEA05550.1 - 4.7e-05 22.9 0.0 0.00021 20.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EEA05550.1 - 0.006 16.2 0.0 0.021 14.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EEA05550.1 - 0.044 13.6 1.0 0.26 11.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Sld5 PF05916.6 EEA05551.1 - 0.008 16.4 0.2 0.016 15.5 0.2 1.6 1 0 0 1 1 1 1 GINS complex protein PRA1 PF03208.14 EEA05552.1 - 7.3e-30 103.3 3.0 1e-29 102.8 2.0 1.1 1 0 0 1 1 1 1 PRA1 family protein FliD_C PF07195.7 EEA05552.1 - 0.0071 15.6 3.2 0.0095 15.2 2.2 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus YwiC PF14256.1 EEA05552.1 - 0.028 14.5 1.1 0.028 14.5 0.8 1.9 1 1 1 2 2 2 0 YwiC-like protein Tic20 PF09685.5 EEA05552.1 - 0.032 14.1 12.1 0.11 12.4 1.0 2.1 2 0 0 2 2 2 0 Tic20-like protein zf-DHHC PF01529.15 EEA05552.1 - 3.5 7.0 6.8 8 5.8 4.7 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF423 PF04241.10 EEA05552.1 - 7.3 6.5 7.2 41 4.1 5.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF423) DUF2516 PF10724.4 EEA05552.1 - 7.8 6.5 7.9 24 4.9 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) KH_1 PF00013.24 EEA05553.1 - 3.8e-05 23.2 0.1 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 KH domain Pkinase PF00069.20 EEA05554.1 - 1.3e-35 122.7 0.0 2e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05554.1 - 7.6e-14 51.3 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05554.1 - 8.1e-10 38.1 0.0 1.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA05554.1 - 0.025 14.3 0.1 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EEA05554.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_ab PF00006.20 EEA05555.1 - 7.5e-60 202.0 0.0 9.8e-60 201.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA05555.1 - 3.2e-17 63.0 0.2 6.3e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA05555.1 - 3.3e-11 43.2 1.2 5.9e-11 42.4 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA05555.1 - 0.00017 21.4 1.5 0.0004 20.2 1.1 1.5 1 0 0 1 1 1 1 HAS barrel domain W2 PF02020.13 EEA05556.1 - 0.0012 18.7 0.8 0.0042 17.0 0.5 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4559 PF15112.1 EEA05557.1 - 0.0047 16.1 6.1 0.0057 15.8 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) YkyA PF10368.4 EEA05557.1 - 0.0048 16.2 10.4 0.15 11.4 0.1 2.0 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein DUF601 PF04642.7 EEA05557.1 - 0.0051 16.2 4.0 0.0061 15.9 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF601 DUF842 PF05811.8 EEA05557.1 - 0.0064 15.9 1.9 0.0085 15.5 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) GAS PF13851.1 EEA05557.1 - 0.0067 15.6 14.5 0.0078 15.4 10.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MCPsignal PF00015.16 EEA05557.1 - 0.013 15.0 1.0 0.015 14.8 0.7 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IL22 PF14565.1 EEA05557.1 - 0.022 14.8 0.6 0.029 14.4 0.4 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Laminin_I PF06008.9 EEA05557.1 - 0.033 13.5 8.0 0.036 13.3 5.6 1.0 1 0 0 1 1 1 0 Laminin Domain I DUF1515 PF07439.6 EEA05557.1 - 0.043 13.6 5.8 0.09 12.5 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF3972 PF13118.1 EEA05557.1 - 0.045 13.8 6.3 0.089 12.8 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DUF4200 PF13863.1 EEA05557.1 - 0.049 13.5 12.5 0.06 13.2 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3402 PF11882.3 EEA05557.1 - 0.049 12.6 5.3 0.056 12.4 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) OmpH PF03938.9 EEA05557.1 - 0.051 13.5 7.7 0.067 13.1 5.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.1 EEA05557.1 - 0.053 13.4 1.5 0.076 13.0 1.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Sulfotransfer_2 PF03567.9 EEA05557.1 - 0.063 12.9 2.6 0.079 12.6 1.8 1.1 1 0 0 1 1 1 0 Sulfotransferase family PA26 PF04636.8 EEA05557.1 - 0.069 11.8 4.7 0.074 11.7 3.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 EEA05557.1 - 0.076 12.6 10.1 0.1 12.1 7.0 1.3 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 EEA05557.1 - 0.096 13.4 9.7 0.15 12.7 6.2 1.7 1 1 1 2 2 2 0 Occludin homology domain Allexi_40kDa PF05549.6 EEA05557.1 - 0.13 11.5 4.5 0.18 11.0 3.1 1.2 1 1 0 1 1 1 0 Allexivirus 40kDa protein PEPcase PF00311.12 EEA05557.1 - 0.13 10.0 3.6 0.14 9.9 2.5 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase FadA PF09403.5 EEA05557.1 - 0.14 12.2 7.2 0.17 11.8 5.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Hom_end PF05204.9 EEA05557.1 - 0.14 12.1 1.0 0.19 11.7 0.7 1.1 1 0 0 1 1 1 0 Homing endonuclease DUF972 PF06156.8 EEA05557.1 - 0.14 12.4 10.3 0.22 11.8 7.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EEA05557.1 - 0.15 11.8 1.6 0.2 11.4 1.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EEA05557.1 - 0.15 10.4 8.2 0.18 10.2 5.7 1.1 1 0 0 1 1 1 0 AAA domain PRESAN PF09687.5 EEA05557.1 - 0.16 12.0 6.1 0.25 11.4 4.2 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Z1 PF10593.4 EEA05557.1 - 0.16 11.1 3.0 0.18 11.0 2.1 1.1 1 0 0 1 1 1 0 Z1 domain DUF3053 PF11254.3 EEA05557.1 - 0.16 11.1 2.0 0.2 10.8 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) CENP-K PF11802.3 EEA05557.1 - 0.17 11.0 8.4 0.21 10.7 5.8 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF342 PF03961.8 EEA05557.1 - 0.18 10.2 8.7 0.2 10.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF725 PF05267.7 EEA05557.1 - 0.21 11.5 1.9 0.79 9.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF725) CorA PF01544.13 EEA05557.1 - 0.24 10.3 7.2 0.28 10.1 5.0 1.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FemAB PF02388.11 EEA05557.1 - 0.25 9.9 5.7 0.29 9.7 4.0 1.0 1 0 0 1 1 1 0 FemAB family DUF2265 PF10023.4 EEA05557.1 - 0.25 10.4 3.0 0.27 10.3 2.1 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) ADIP PF11559.3 EEA05557.1 - 0.29 11.0 12.1 0.21 11.4 7.3 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EEA05557.1 - 0.29 10.1 9.8 0.35 9.8 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EEA05557.1 - 0.29 11.5 7.5 2.4 8.6 1.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 EEA05557.1 - 0.3 11.2 9.3 0.36 10.9 6.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.1 EEA05557.1 - 0.34 10.8 8.0 0.43 10.5 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Mer2 PF09074.5 EEA05557.1 - 0.36 10.7 9.3 0.72 9.7 6.5 1.5 1 1 0 1 1 1 0 Mer2 DUF948 PF06103.6 EEA05557.1 - 0.4 10.5 6.0 1.6 8.6 1.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2422 PF10337.4 EEA05557.1 - 0.43 9.3 2.8 0.49 9.1 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4220 PF13968.1 EEA05557.1 - 0.49 9.4 2.0 0.55 9.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) ALIX_LYPXL_bnd PF13949.1 EEA05557.1 - 0.55 9.1 11.4 1.6 7.6 7.9 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4509 PF14970.1 EEA05557.1 - 0.65 9.6 4.5 0.79 9.3 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF3810 PF12725.2 EEA05557.1 - 0.71 8.7 3.2 0.89 8.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) V_ATPase_I PF01496.14 EEA05557.1 - 0.75 7.5 8.2 0.79 7.4 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L3 PF00297.17 EEA05557.1 - 0.88 8.9 6.7 0.99 8.7 0.6 2.0 1 1 1 2 2 2 0 Ribosomal protein L3 SLIDE PF09111.5 EEA05557.1 - 0.9 9.2 7.2 8.6 6.1 2.1 2.1 2 0 0 2 2 2 0 SLIDE DUF3635 PF12330.3 EEA05557.1 - 0.9 9.6 4.2 0.92 9.6 2.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3635) Seryl_tRNA_N PF02403.17 EEA05557.1 - 0.98 9.4 11.4 1.3 9.0 6.8 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Acetyltransf_11 PF13720.1 EEA05557.1 - 1.1 9.5 3.6 1.1 9.5 0.1 2.2 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF4363 PF14276.1 EEA05557.1 - 1.4 8.5 7.6 2.4 7.8 1.4 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) DUF4140 PF13600.1 EEA05557.1 - 1.8 9.0 7.5 0.59 10.6 2.4 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_Mu_Gam PF07352.7 EEA05557.1 - 1.9 8.0 11.6 0.7 9.4 1.4 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Syntaxin PF00804.20 EEA05557.1 - 1.9 8.7 11.3 2.7 8.1 7.8 1.3 1 1 0 1 1 1 0 Syntaxin Atg14 PF10186.4 EEA05557.1 - 3 6.7 9.4 3.7 6.4 6.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 EEA05557.1 - 3.2 7.5 14.0 0.7 9.6 1.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF1043 PF06295.7 EEA05557.1 - 3.4 7.3 8.1 1.6 8.3 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.7 EEA05557.1 - 4.3 7.1 6.4 7 6.4 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AKNA PF12443.3 EEA05557.1 - 5 7.1 8.2 9 6.3 3.7 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor GrpE PF01025.14 EEA05557.1 - 5.8 6.4 10.6 13 5.3 6.4 1.9 1 1 0 1 1 1 0 GrpE TMPIT PF07851.8 EEA05557.1 - 6.7 5.6 7.3 7.8 5.4 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.1 EEA05557.1 - 7.5 7.0 8.1 10 6.6 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF4337 PF14235.1 EEA05557.1 - 8.3 6.2 9.6 35 4.1 6.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Fe-ADH PF00465.14 EEA05558.1 - 3.3e-51 174.0 0.0 1.8e-49 168.3 0.0 2.0 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA05558.1 - 1.3e-05 24.6 1.3 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EEA05559.1 - 5.2e-109 364.2 0.0 9.1e-109 363.4 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA05559.1 - 8.3e-22 77.6 1.4 3.6e-11 42.8 0.0 2.6 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Aldedh PF00171.17 EEA05559.1 - 1.4e-19 69.7 1.3 1.2e-18 66.6 0.9 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family UPF0061 PF02696.9 EEA05559.1 - 0.15 10.3 0.0 0.31 9.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family ThiF PF00899.16 EEA05560.1 - 8.6e-27 93.6 0.0 3.1e-26 91.8 0.0 2.0 2 1 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.4 EEA05560.1 - 6.3e-12 44.6 3.9 1.5e-11 43.4 2.7 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 EEA05560.1 - 1.9e-11 43.3 0.3 3.9e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein SHMT PF00464.14 EEA05563.1 - 0.013 13.8 0.1 0.037 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Tim44 PF04280.10 EEA05563.1 - 0.061 13.3 0.1 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 Tim44-like domain SHMT PF00464.14 EEA05564.1 - 4.3e-09 35.2 0.0 5.2e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ubiquitin PF00240.18 EEA05565.1 - 9.1e-11 41.0 0.1 0.032 13.6 0.0 6.1 6 0 0 6 6 6 3 Ubiquitin family Rad60-SLD PF11976.3 EEA05565.1 - 5e-07 29.3 0.6 0.59 9.8 0.0 6.5 6 0 0 6 6 6 2 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.15 EEA05565.1 - 0.04 13.9 0.1 0.73 9.9 0.0 3.0 3 0 0 3 3 3 0 UBX domain fn2 PF00040.14 EEA05566.1 - 1.5e-06 28.0 0.8 41 4.2 0.0 7.6 8 0 0 8 8 8 2 Fibronectin type II domain Glutenin_hmw PF03157.8 EEA05566.1 - 0.0012 17.1 9.8 0.02 13.2 6.7 2.1 1 1 0 1 1 1 1 High molecular weight glutenin subunit DUF575 PF04746.7 EEA05569.1 - 2.4 8.2 4.8 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF575) SURF6 PF04935.7 EEA05570.1 - 8.5e-06 25.2 38.2 8.5e-06 25.2 26.5 1.9 2 0 0 2 2 2 1 Surfeit locus protein 6 DEAD PF00270.24 EEA05571.1 - 5.7e-41 139.8 0.0 8e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA05571.1 - 1e-23 82.9 0.1 1.7e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Apc3 PF12895.2 EEA05572.1 - 0.001 19.1 1.0 0.071 13.2 0.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 LisH PF08513.6 EEA05572.1 - 0.0015 18.2 1.7 0.0022 17.6 0.6 1.8 2 0 0 2 2 2 1 LisH TPR_2 PF07719.12 EEA05572.1 - 0.012 15.4 1.6 1.3 9.1 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CLTH PF10607.4 EEA05572.1 - 0.013 15.1 7.9 0.11 12.1 3.6 2.1 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain TPR_1 PF00515.23 EEA05572.1 - 0.042 13.4 3.2 2.4 7.9 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA05572.1 - 0.067 12.8 2.2 7 6.3 0.3 3.0 3 0 0 3 3 3 0 TPR repeat Cmc1 PF08583.5 EEA05572.1 - 0.077 12.7 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_7 PF13176.1 EEA05572.1 - 0.086 12.6 1.4 3.4 7.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat eRF1_1 PF03463.10 EEA05573.1 - 1.1e-29 102.6 0.1 1.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EEA05573.1 - 1.1e-21 77.1 0.0 2.8e-20 72.6 0.0 2.5 1 1 1 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.10 EEA05573.1 - 4.1e-16 59.5 0.4 1e-15 58.2 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 2 ERF PF04404.7 EEA05573.1 - 0.016 14.7 0.5 0.035 13.6 0.3 1.6 1 0 0 1 1 1 0 ERF superfamily DUF3216 PF11505.3 EEA05573.1 - 0.031 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Ribosomal_S4 PF00163.14 EEA05574.1 - 2e-23 82.6 1.8 3.9e-23 81.6 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEA05574.1 - 5.2e-12 45.0 0.7 1.3e-11 43.7 0.5 1.7 1 0 0 1 1 1 1 S4 domain E2F_TDP PF02319.15 EEA05575.1 - 7.8e-13 47.7 0.0 1.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LisH PF08513.6 EEA05576.1 - 1.8e-06 27.5 0.1 3.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EEA05576.1 - 2.1e-05 24.2 0.6 0.071 13.0 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-C3HC4 PF00097.20 EEA05577.1 - 1.3e-06 27.9 12.9 3.6e-06 26.5 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05577.1 - 3.6e-06 26.8 14.4 9.3e-06 25.5 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA05577.1 - 8.3e-06 25.3 12.1 1.5e-05 24.5 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA05577.1 - 1.9e-05 24.3 12.4 4.3e-05 23.1 8.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA05577.1 - 8.8e-05 22.2 12.3 0.0002 21.1 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EEA05577.1 - 0.00014 21.6 6.5 0.00033 20.3 4.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EEA05577.1 - 0.034 13.8 8.7 0.15 11.7 6.0 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA05577.1 - 0.3 10.9 11.3 0.93 9.4 7.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EEA05577.1 - 0.58 9.7 6.7 1.5 8.4 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EEA05577.1 - 1.6 8.3 10.1 4.9 6.8 7.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain VPS9 PF02204.13 EEA05578.1 - 1.9e-23 82.4 0.2 6.1e-23 80.8 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain POT1 PF02765.12 EEA05578.1 - 0.032 14.1 0.6 0.032 14.1 0.4 2.2 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 ELMO_CED12 PF04727.8 EEA05579.1 - 6.5e-35 120.1 1.6 1.5e-34 118.9 1.1 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family Plant_all_beta PF10532.4 EEA05579.1 - 0.027 14.5 9.3 0.056 13.5 6.0 1.9 1 1 0 1 1 1 0 Plant specific N-all beta domain DUF3394 PF11874.3 EEA05580.1 - 0.06 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) ENTH PF01417.15 EEA05582.1 - 2.4e-34 117.8 0.2 6.2e-34 116.5 0.1 1.7 1 0 0 1 1 1 1 ENTH domain PMI_typeI PF01238.16 EEA05583.1 - 1.7e-71 241.1 0.3 6.1e-71 239.3 0.2 1.8 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cytidylate_kin2 PF13189.1 EEA05583.1 - 0.077 12.9 0.7 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 Cytidylate kinase-like family HEAT PF02985.17 EEA05584.1 - 9.8e-23 78.1 11.7 0.0035 17.3 0.0 10.5 9 0 0 9 9 9 6 HEAT repeat CLASP_N PF12348.3 EEA05584.1 - 1.9e-15 56.8 16.9 3e-11 43.1 0.1 6.7 7 1 1 8 8 8 3 CLASP N terminal HEAT_2 PF13646.1 EEA05584.1 - 4.3e-15 55.7 1.6 0.0061 16.8 0.1 7.7 7 1 1 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EEA05584.1 - 3.1e-11 43.4 9.5 0.11 13.0 0.0 10.6 10 2 3 13 13 13 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA05584.1 - 8.4e-10 38.9 13.1 0.048 14.0 0.0 9.5 10 0 0 10 10 10 4 Vacuolar 14 Fab1-binding region Helicase_C_3 PF13625.1 EEA05585.1 - 2.3e-21 75.9 0.0 4.2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA05585.1 - 1e-13 51.5 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA05585.1 - 8.9e-10 38.3 0.1 3.5e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cwf_Cwc_15 PF04889.7 EEA05586.1 - 4.1e-29 101.9 27.6 1.9e-27 96.5 16.5 2.1 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein ICA69 PF04629.9 EEA05586.1 - 0.23 11.3 9.5 0.3 11.0 6.6 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain IncA PF04156.9 EEA05586.1 - 2.5 7.6 11.4 3.6 7.1 7.9 1.3 1 0 0 1 1 1 0 IncA protein NAD_kinase PF01513.16 EEA05588.1 - 4.2e-51 173.4 0.0 6.2e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase WD40 PF00400.27 EEA05589.1 - 1.1e-13 50.5 9.1 0.0076 16.0 0.0 6.0 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF1900 PF08954.6 EEA05589.1 - 0.088 12.3 0.0 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) Dynamin_N PF00350.18 EEA05590.1 - 3.7e-16 59.3 0.1 3.7e-16 59.3 0.1 2.1 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EEA05590.1 - 0.002 18.0 1.0 0.019 14.9 0.7 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA05590.1 - 0.005 17.3 0.1 0.031 14.7 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EEA05590.1 - 0.011 15.0 0.1 3 7.0 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEA05590.1 - 0.032 13.6 0.1 0.54 9.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EEA05590.1 - 0.08 12.6 0.1 0.47 10.1 0.0 2.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEA05590.1 - 0.14 12.0 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GNAT_acetyltr_2 PF13718.1 EEA05591.1 - 3.4e-66 222.3 0.0 6.8e-66 221.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EEA05591.1 - 5.4e-58 195.5 0.0 1.1e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EEA05591.1 - 2.2e-29 100.9 0.0 6.5e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EEA05591.1 - 8.9e-26 89.9 0.4 2.5e-25 88.5 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EEA05591.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.19 EEA05592.1 - 7.6e-10 38.6 0.0 1.6e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA05592.1 - 2.1e-06 27.7 1.3 1.8e-05 24.8 0.9 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA05592.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EEA05592.1 - 0.0027 17.6 0.9 0.0071 16.3 0.2 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA05592.1 - 0.0069 16.2 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA05592.1 - 0.019 15.1 0.1 0.37 10.9 0.1 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain OGG_N PF07934.7 EEA05593.1 - 1.4e-22 79.8 0.9 1.5e-21 76.5 0.6 2.5 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EEA05593.1 - 2.6e-08 34.1 0.0 1.8e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEA05593.1 - 0.0043 16.6 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif TBP PF00352.16 EEA05594.1 - 4.6e-61 202.1 0.0 6.4e-30 102.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEA05594.1 - 0.12 12.4 0.0 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) BTB_2 PF02214.17 EEA05595.1 - 4.6e-14 52.3 0.4 1.3e-13 50.9 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain S1 PF00575.18 EEA05596.1 - 3.5e-25 87.8 14.0 2.6e-06 27.4 0.0 8.4 9 0 0 9 9 9 5 S1 RNA binding domain TPR_19 PF14559.1 EEA05596.1 - 5e-06 26.7 0.0 0.3 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA05596.1 - 5.7e-05 23.3 0.0 0.02 15.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA05596.1 - 0.00066 20.2 0.0 0.35 11.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EEA05596.1 - 0.00077 19.2 22.3 0.072 12.8 1.2 4.5 2 2 2 4 4 4 3 Suppressor of forked protein (Suf) EXOSC1 PF10447.4 EEA05596.1 - 0.0047 16.8 6.7 9.1 6.3 0.0 6.0 5 0 0 5 5 5 1 Exosome component EXOSC1/CSL4 TPR_6 PF13174.1 EEA05596.1 - 0.082 13.3 0.0 1.3 9.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 EEA05600.1 - 2e-28 98.9 0.6 4.3e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EEA05600.1 - 9.1e-19 68.3 0.0 4.8e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA05600.1 - 6.1e-14 52.9 0.0 2.1e-06 28.3 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EEA05600.1 - 2.4e-10 40.3 0.9 8.1e-10 38.6 0.6 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 EEA05600.1 - 1.3e-07 31.4 0.5 5.5e-07 29.4 0.4 2.1 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA05600.1 - 0.014 14.9 3.1 0.044 13.3 0.0 3.0 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase Ran_BP1 PF00638.13 EEA05601.1 - 3.5e-08 33.5 4.1 7.7e-08 32.4 0.6 2.7 2 1 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 EEA05601.1 - 0.0073 16.6 1.0 0.019 15.2 0.7 1.8 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) PX PF00787.19 EEA05602.1 - 6.8e-10 38.7 0.6 9.8e-10 38.2 0.4 1.2 1 0 0 1 1 1 1 PX domain Ins145_P3_rec PF08709.6 EEA05603.1 - 0.0009 18.3 0.0 0.068 12.1 0.0 2.1 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.14 EEA05603.1 - 0.0092 15.5 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 1 MIR domain IL12p40_C PF10420.4 EEA05603.1 - 0.013 15.5 2.0 0.084 12.9 0.0 2.3 1 1 1 2 2 2 0 Cytokine interleukin-12p40 C-terminus DDE_Tnp_1_6 PF13751.1 EEA05603.1 - 0.46 10.4 2.8 0.39 10.7 0.2 1.9 1 1 1 2 2 2 0 Transposase DDE domain SOUL PF04832.7 EEA05604.1 - 4.6e-24 84.9 0.0 5.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Aha1_N PF09229.6 EEA05605.1 - 6.2e-16 58.4 2.3 6.2e-16 58.4 1.6 2.4 3 0 0 3 3 3 1 Activator of Hsp90 ATPase, N-terminal TPR_11 PF13414.1 EEA05605.1 - 3.1e-09 36.3 3.0 4.6e-05 22.9 0.2 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEA05605.1 - 1.5e-06 27.5 4.9 0.0063 16.0 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05605.1 - 3.4e-06 26.5 0.4 0.13 12.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 EEA05605.1 - 0.005 16.6 1.2 0.094 12.6 0.2 2.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 EEA05605.1 - 0.0058 16.3 6.9 17 5.4 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA05605.1 - 0.017 15.8 0.5 2.4 8.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEA05605.1 - 0.026 14.3 2.3 0.039 13.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA05605.1 - 0.07 13.0 1.3 0.37 10.6 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EEA05605.1 - 0.63 10.6 3.6 22 5.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat CTD_bind PF04818.8 EEA05606.1 - 0.0044 17.2 0.1 0.014 15.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Mt_ATP-synt_B PF05405.9 EEA05606.1 - 0.006 16.0 1.6 0.0091 15.4 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Erp_C PF06780.6 EEA05606.1 - 0.026 14.3 0.5 0.039 13.7 0.4 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Syntaxin_2 PF14523.1 EEA05606.1 - 0.032 14.2 3.1 0.061 13.3 2.1 1.4 1 0 0 1 1 1 0 Syntaxin-like protein PCNA_N PF00705.13 EEA05607.1 - 4.2e-43 145.8 0.9 1.3e-42 144.2 0.4 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EEA05607.1 - 3.3e-39 133.7 0.0 9.6e-39 132.2 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EEA05607.1 - 1.3e-08 33.9 0.5 8.6e-06 24.7 0.3 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EEA05607.1 - 0.0003 19.9 1.1 0.00044 19.4 0.8 1.4 1 1 0 1 1 1 1 Rad9 Histone PF00125.19 EEA05608.1 - 1.3e-27 95.7 0.1 1.7e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA05608.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YdfA_immunity PF12127.3 EEA05608.1 - 0.076 11.9 0.0 0.089 11.6 0.0 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial Pkinase PF00069.20 EEA05609.1 - 7e-55 185.9 3.1 7e-55 185.9 2.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05609.1 - 7.2e-39 133.4 0.5 1.6e-38 132.2 0.3 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05609.1 - 0.00042 19.3 1.1 0.0006 18.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Imm46 PF15585.1 EEA05610.1 - 0.052 13.5 0.4 0.088 12.8 0.2 1.3 1 1 0 1 1 1 0 Immunity protein 46 Actin PF00022.14 EEA05611.1 - 3.3e-111 371.5 0.0 3.7e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA05611.1 - 0.00011 20.9 0.1 0.013 14.1 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein RCC1_2 PF13540.1 EEA05612.1 - 7.1e-22 76.4 3.6 1.5e-07 30.8 0.1 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EEA05612.1 - 1.4e-18 66.7 9.6 4.9e-09 36.2 0.0 7.0 8 2 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat HeH PF12949.2 EEA05613.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain HAP2-GCS1 PF10699.4 EEA05614.1 - 5.2e-13 48.7 0.0 5.2e-13 48.7 0.0 2.5 3 0 0 3 3 3 1 Male gamete fusion factor His_Phos_1 PF00300.17 EEA05615.1 - 1.9e-09 37.8 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) XRN_N PF03159.13 EEA05616.1 - 3.9e-98 327.5 0.0 9.3e-98 326.3 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RHH_3 PF12651.2 EEA05616.1 - 0.52 10.0 3.3 8.2 6.2 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix domain Phosphodiest PF01663.17 EEA05617.1 - 0.00054 19.3 0.2 0.0015 17.9 0.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA05617.1 - 0.0091 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Globin PF00042.17 EEA05617.1 - 0.037 14.3 0.3 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Globin LRR_1 PF00560.28 EEA05618.1 - 1 9.6 5.5 60 4.2 0.2 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat Fumarate_red_D PF02313.12 EEA05619.1 - 0.79 9.6 4.4 2.7 7.9 1.3 2.5 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF281 PF03436.8 EEA05620.1 - 0.056 13.5 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF281) SNF2_N PF00176.18 EEA05621.1 - 1.3e-65 221.1 0.1 1.3e-65 221.1 0.0 3.7 4 0 0 4 4 4 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEA05621.1 - 2.8e-15 56.0 0.0 7.6e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EEA05621.1 - 6e-15 54.8 0.2 4.5e-14 52.0 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA05621.1 - 2e-11 44.0 0.0 1.3e-10 41.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EEA05621.1 - 3.8e-07 29.2 0.1 1.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EEA05621.1 - 5.9e-07 29.1 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CLTH PF10607.4 EEA05621.1 - 0.031 13.9 6.9 0.041 13.5 3.3 2.3 3 0 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain AAA_22 PF13401.1 EEA05621.1 - 0.54 10.4 4.5 1.1 9.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain Nucleoplasmin PF03066.10 EEA05621.1 - 8.6 5.8 20.4 34 3.9 14.1 2.0 1 0 0 1 1 1 0 Nucleoplasmin Chordopox_A13L PF05961.6 EEA05622.1 - 4 7.4 8.1 0.21 11.5 0.8 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein BACK PF07707.10 EEA05625.1 - 1.9e-05 24.4 0.8 5e-05 23.0 0.6 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch FAD_binding_8 PF08022.7 EEA05625.1 - 0.059 13.2 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 FAD-binding domain PNTB PF02233.11 EEA05626.1 - 3.8e-179 596.3 14.2 3.8e-179 596.3 9.8 1.5 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EEA05626.1 - 1.3e-46 158.2 0.6 2.5e-46 157.3 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EEA05626.1 - 5.7e-42 142.9 0.0 1.1e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EEA05626.1 - 8.9e-31 105.9 7.4 8.9e-31 105.9 5.1 3.5 3 2 1 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EEA05626.1 - 6.1e-05 22.2 0.6 0.28 10.3 0.0 2.9 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EEA05626.1 - 0.00047 20.0 0.1 0.0013 18.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEA05626.1 - 0.011 15.8 4.6 0.25 11.4 1.3 3.6 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EEA05626.1 - 0.038 14.3 0.6 0.18 12.2 0.4 2.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EEA05626.1 - 0.044 13.3 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 EEA05626.1 - 0.046 13.7 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA05626.1 - 0.057 12.2 0.1 0.087 11.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EEA05626.1 - 0.088 12.4 0.7 0.89 9.1 0.5 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CSD PF00313.17 EEA05627.1 - 8e-24 83.2 0.3 1.1e-23 82.8 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EEA05627.1 - 2.8e-06 26.7 0.3 2.8e-06 26.7 0.2 2.6 3 0 0 3 3 3 1 Ribonuclease B OB domain FXR1P_C PF12235.3 EEA05627.1 - 0.0027 17.8 6.4 0.0033 17.5 4.4 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal Glycolipid_bind PF06475.6 EEA05627.1 - 0.095 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative glycolipid-binding DUF1633 PF07794.6 EEA05627.1 - 0.22 9.4 3.0 0.24 9.3 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Pro_isomerase PF00160.16 EEA05628.1 - 1.8e-35 122.4 0.1 1e-34 120.0 0.1 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EEA05628.1 - 2e-18 65.7 0.0 3.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05628.1 - 4.2e-13 49.0 0.0 8.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05628.1 - 5.6e-09 35.7 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Romo1 PF10247.4 EEA05629.1 - 2.9e-20 72.2 8.0 3.7e-20 71.8 5.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF2759 PF10958.3 EEA05629.1 - 0.078 12.5 1.0 0.16 11.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Gly-zipper_OmpA PF13436.1 EEA05629.1 - 0.11 12.1 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PfkB PF00294.19 EEA05630.1 - 3.7e-34 118.2 0.0 6.5e-18 64.8 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase LAGLIDADG_1 PF00961.14 EEA05630.1 - 0.099 13.2 1.7 0.32 11.5 0.3 2.4 1 1 1 2 2 2 0 LAGLIDADG endonuclease CDC45 PF02724.9 EEA05631.1 - 1.4e-31 109.2 5.8 1e-30 106.4 4.0 2.0 1 1 0 1 1 1 1 CDC45-like protein RNA_polI_A14 PF08203.6 EEA05631.1 - 0.4 10.9 2.2 1.5 9.0 0.2 3.0 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 DUF1003 PF06210.6 EEA05631.1 - 0.69 9.8 6.6 0.82 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) V-ATPase_G PF03179.10 EEA05632.1 - 4e-07 30.2 3.8 4.6e-07 30.0 1.4 1.9 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EEA05632.1 - 0.047 13.4 4.9 1.6 8.5 1.7 2.6 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) RHD3 PF05879.7 EEA05633.1 - 1.4e-78 264.6 25.8 1.9e-71 241.0 9.4 3.2 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EEA05633.1 - 4.9e-06 25.7 0.7 1.6e-05 24.0 0.5 1.9 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Miro PF08477.8 EEA05633.1 - 0.00027 21.3 0.0 0.00096 19.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA05633.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA05633.1 - 0.00038 20.3 0.1 0.0012 18.6 0.1 1.9 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EEA05633.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA05633.1 - 0.06 13.6 0.1 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TFIIF_beta PF02270.10 EEA05634.1 - 8.5e-10 38.8 1.3 3.5e-07 30.3 0.9 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit RPA_C PF08784.6 EEA05634.1 - 0.0033 17.8 1.1 0.0061 16.9 0.2 1.9 2 0 0 2 2 2 1 Replication protein A C terminal Pkinase_Tyr PF07714.12 EEA05635.1 - 1.9e-60 204.1 0.0 2.6e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEA05635.1 - 2.9e-59 200.3 0.0 4.9e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.25 EEA05635.1 - 3.4e-08 33.5 0.0 8.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEA05635.1 - 5.3e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MORN PF02493.15 EEA05635.1 - 0.00011 21.7 13.3 0.018 14.7 0.3 4.7 4 0 0 4 4 4 2 MORN repeat Kinase-like PF14531.1 EEA05635.1 - 0.031 13.2 0.0 0.062 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EEA05635.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EEA05636.1 - 3e-11 42.9 0.3 7.7e-11 41.6 0.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EEA05636.1 - 0.0019 17.2 0.0 0.0041 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.17 EEA05636.1 - 0.019 14.9 0.0 4.3 7.6 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat DUF1442 PF07279.6 EEA05636.1 - 0.034 13.2 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) FH2 PF02181.18 EEA05637.1 - 2.8e-38 131.7 8.5 7e-24 84.4 2.7 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain SAP PF02037.22 EEA05638.1 - 2.9e-07 29.8 0.7 2.8e-06 26.6 0.0 2.7 4 0 0 4 4 4 1 SAP domain OST-HTH PF12872.2 EEA05638.1 - 0.0027 17.5 0.0 0.0076 16.0 0.0 1.8 1 0 0 1 1 1 1 OST-HTH/LOTUS domain OmpH PF03938.9 EEA05638.1 - 0.016 15.1 8.1 0.016 15.1 5.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LETM1 PF07766.8 EEA05638.1 - 0.061 12.3 0.2 0.061 12.3 0.2 2.4 2 1 1 3 3 3 0 LETM1-like protein VWA_N PF08399.6 EEA05638.1 - 0.75 10.4 9.0 0.53 10.9 0.3 3.1 3 0 0 3 3 3 0 VWA N-terminal DUF1144 PF06610.8 EEA05643.1 - 0.014 15.1 0.1 6.6 6.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1144) CKS PF01111.14 EEA05644.1 - 4.2e-32 109.7 0.2 5.8e-32 109.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DSHCT PF08148.7 EEA05645.1 - 1.9e-54 183.6 0.1 4.1e-54 182.5 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEA05645.1 - 4.3e-21 75.1 0.0 1.7e-20 73.1 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EEA05645.1 - 5.6e-14 51.9 20.8 1.3e-12 47.5 2.7 3.7 3 1 0 3 3 3 2 rRNA-processing arch domain Helicase_C PF00271.26 EEA05645.1 - 7.7e-06 25.6 0.0 3.3e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sushi PF00084.15 EEA05646.1 - 8.4e-07 29.2 0.1 2.2e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Troponin PF00992.15 EEA05647.1 - 0.02 14.9 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Troponin Med22 PF06179.7 EEA05647.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex zf-RING_2 PF13639.1 EEA05649.1 - 8e-12 44.8 6.0 1.4e-11 44.0 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA05649.1 - 1.8e-07 31.1 7.5 7.6e-07 29.1 5.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEA05649.1 - 3.6e-07 29.7 2.5 6.5e-07 28.9 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA05649.1 - 3.8e-07 29.6 4.7 8.3e-07 28.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA05649.1 - 7.3e-07 29.1 6.3 7.3e-07 29.1 4.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA05649.1 - 1.4e-06 27.9 3.5 2.5e-06 27.0 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA05649.1 - 0.0004 20.1 0.5 0.00096 18.9 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEA05649.1 - 0.0037 16.9 4.5 0.01 15.5 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA05649.1 - 0.16 11.8 6.2 0.39 10.6 4.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEA05649.1 - 0.29 11.1 2.6 0.95 9.4 1.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEA05649.1 - 0.71 9.5 3.2 1.5 8.4 2.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 EEA05649.1 - 1.6 8.5 4.4 0.96 9.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING-like PF08746.6 EEA05649.1 - 1.8 8.6 5.6 1.8 8.6 2.9 1.8 2 0 0 2 2 2 0 RING-like domain SHMT PF00464.14 EEA05651.1 - 1.4e-77 260.7 0.0 4.6e-77 259.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydroxymethyltransferase DUF2116 PF09889.4 EEA05652.1 - 5.7 6.8 8.5 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF632 PF04782.7 EEA05653.1 - 0.031 13.3 2.4 0.051 12.6 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF632) DUF1664 PF07889.7 EEA05653.1 - 1.5 8.6 6.9 2.1 8.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 EEA05653.1 - 1.5 8.4 6.7 0.84 9.2 0.5 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region MitMem_reg PF13012.1 EEA05654.1 - 0.086 12.9 0.7 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function SHMT PF00464.14 EEA05655.1 - 1.8e-129 431.6 0.0 2.2e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MtrC PF04211.8 EEA05656.1 - 0.054 12.5 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Autophagy_N PF03986.8 EEA05657.1 - 2.2e-26 92.3 0.2 3e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EEA05657.1 - 8.1e-26 89.9 0.7 1.7e-25 88.9 0.5 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EEA05657.1 - 3.5e-10 38.7 0.5 7.5e-10 37.7 0.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-Nse PF11789.3 EEA05658.1 - 7e-16 57.4 1.5 1.4e-15 56.5 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit GMC_oxred_C PF05199.8 EEA05661.1 - 2.4e-25 89.5 0.0 4.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EEA05661.1 - 1.2e-18 67.2 0.0 2.1e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.12 EEA05661.1 - 1.7e-05 24.0 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEA05661.1 - 4.5e-05 22.5 0.1 6.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA05661.1 - 0.00012 20.7 0.1 0.00021 19.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA05661.1 - 0.00012 21.0 0.1 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEA05661.1 - 0.00014 21.7 0.1 0.00033 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA05661.1 - 0.00059 20.1 0.2 0.0021 18.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA05661.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EEA05661.1 - 0.0017 16.7 0.0 0.0027 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EEA05661.1 - 0.0019 17.3 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EEA05661.1 - 0.0042 16.0 1.4 0.007 15.2 0.9 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEA05661.1 - 0.0058 15.5 0.1 0.0087 15.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EEA05661.1 - 0.025 13.6 0.1 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EEA05661.1 - 0.026 14.1 0.1 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VRP3 PF03536.10 EEA05661.1 - 0.046 12.8 0.7 0.088 11.9 0.2 1.6 2 0 0 2 2 2 0 Salmonella virulence-associated 28kDa protein RE_EcoO109I PF14511.1 EEA05663.1 - 0.0089 15.4 0.1 0.016 14.6 0.0 1.5 1 1 0 1 1 1 1 Type II restriction endonuclease EcoO109I Lipase_2 PF01674.13 EEA05663.1 - 0.06 12.6 5.5 0.077 12.2 3.8 1.4 1 0 0 1 1 1 0 Lipase (class 2) zf-HIT PF04438.11 EEA05663.1 - 0.1 12.2 9.2 0.29 10.7 6.4 1.9 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EEA05664.1 - 4.1e-46 157.6 0.0 7e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EEA05665.1 - 8.1e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA05665.1 - 0.029 14.3 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_M16 PF00675.15 EEA05666.1 - 7.2e-10 38.8 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA05666.1 - 5.1e-09 36.0 0.2 5.3e-08 32.7 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain SET PF00856.23 EEA05667.1 - 1.1e-22 81.0 0.9 1.1e-22 81.0 0.6 2.6 2 0 0 2 2 2 1 SET domain Bromodomain PF00439.20 EEA05667.1 - 8.1e-10 38.4 1.6 8.1e-10 38.4 1.1 2.9 3 0 0 3 3 3 1 Bromodomain PHD PF00628.24 EEA05667.1 - 1.5e-08 34.2 97.3 8.5e-07 28.5 5.2 9.5 8 1 1 9 9 9 6 PHD-finger Phage_head_chap PF11113.3 EEA05667.1 - 0.0029 17.4 0.3 0.011 15.5 0.2 2.1 1 0 0 1 1 1 1 Head assembly gene product SNF2_N PF00176.18 EEA05672.1 - 4.6e-72 242.3 3.7 1.2e-71 240.9 2.5 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA05672.1 - 2.7e-15 55.9 0.0 6.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sporozoite_P67 PF05642.6 EEA05672.1 - 0.0042 15.0 10.1 0.0074 14.2 7.0 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF106 PF01956.11 EEA05673.1 - 5.5e-26 91.1 0.1 2.8e-25 88.7 0.0 1.8 1 1 0 1 1 1 1 Integral membrane protein DUF106 Notch PF00066.12 EEA05675.1 - 8.3e-49 163.5 111.0 1.4e-09 38.0 6.9 6.4 4 1 2 6 6 6 6 LNR domain UPRTase PF14681.1 EEA05676.1 - 3.3e-63 212.6 0.0 4.6e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EEA05676.1 - 8.3e-47 159.2 0.0 1.9e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EEA05676.1 - 5.3e-07 30.0 0.1 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA05676.1 - 4.6e-05 24.2 0.2 0.00011 22.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EEA05676.1 - 0.0025 17.2 0.2 0.19 11.0 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.7 EEA05676.1 - 0.0031 16.6 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EEA05676.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.26 EEA05677.1 - 1e-20 73.1 0.2 2.1e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain LRR_4 PF12799.2 EEA05678.1 - 0.00029 20.4 42.1 0.00051 19.5 5.7 7.6 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEA05678.1 - 0.013 15.4 0.7 0.013 15.4 0.5 7.4 9 0 0 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 EEA05678.1 - 0.52 10.7 18.3 2.7 8.6 0.4 7.1 8 0 0 8 8 8 0 Leucine rich repeat LRR_8 PF13855.1 EEA05678.1 - 4 7.2 25.7 1.1 9.0 2.6 6.3 5 2 0 6 6 6 0 Leucine rich repeat HABP4_PAI-RBP1 PF04774.10 EEA05681.1 - 6.3e-05 23.4 1.9 8.9e-05 22.9 1.3 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DnaJ PF00226.26 EEA05682.1 - 1.1e-07 31.5 1.3 3e-07 30.0 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain Toxin_9 PF02819.10 EEA05682.1 - 0.34 11.0 4.1 0.68 10.0 2.8 1.4 1 0 0 1 1 1 0 Spider toxin Ribosomal_L1 PF00687.16 EEA05683.1 - 5.8e-50 169.6 4.8 6.9e-50 169.4 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family OGFr_N PF04664.8 EEA05683.1 - 0.05 12.9 0.2 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region DUF1777 PF08648.7 EEA05684.1 - 1.3e-20 73.8 11.2 1.6e-20 73.5 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF4634 PF15465.1 EEA05684.1 - 0.18 11.9 1.7 0.25 11.5 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) SUI1 PF01253.17 EEA05685.1 - 9.8e-20 70.1 1.1 1.3e-19 69.7 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 Rsbr_N PF08678.5 EEA05685.1 - 0.019 14.8 0.3 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 Rsbr N terminal COPIIcoated_ERV PF07970.7 EEA05686.1 - 7.9e-48 162.9 4.9 1.2e-47 162.3 3.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEA05686.1 - 6.1e-22 77.4 0.3 6.3e-21 74.1 0.0 2.6 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.25 EEA05687.1 - 2.2e-28 97.8 0.1 1.9e-06 27.6 0.0 5.8 5 0 0 5 5 5 5 C2 domain PTEN_C2 PF10409.4 EEA05687.1 - 0.00048 19.8 0.2 0.0026 17.4 0.0 2.3 3 0 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein FerI PF08151.7 EEA05687.1 - 0.0042 17.0 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 FerI (NUC094) domain Snf7 PF03357.16 EEA05688.1 - 1.6e-08 34.1 15.8 2.8e-08 33.3 11.0 1.3 1 0 0 1 1 1 1 Snf7 ZapA PF05164.8 EEA05688.1 - 0.21 11.5 5.3 0.6 10.1 3.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapA Enkurin PF13864.1 EEA05688.1 - 9.8 6.4 9.9 6.8 6.9 1.7 2.8 2 0 0 2 2 2 0 Calmodulin-binding Fumerase PF05681.9 EEA05689.1 - 4.6e-78 262.0 0.0 6.3e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 EEA05689.1 - 3.9e-65 218.8 0.0 5.4e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus GTP_EFTU PF00009.22 EEA05690.1 - 2.1e-61 206.6 0.1 3e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEA05690.1 - 1.2e-35 121.6 0.0 3.1e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEA05690.1 - 4.9e-21 74.4 0.0 1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEA05690.1 - 9.5e-15 54.2 0.0 1.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEA05690.1 - 2.5e-12 46.7 0.1 6.1e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA05690.1 - 0.00017 21.5 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DNA_pol3_delta2 PF13177.1 EEA05691.1 - 3.2e-17 62.6 0.1 1.2e-16 60.7 0.1 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEA05691.1 - 7.7e-14 52.0 0.0 2.1e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EEA05691.1 - 4.9e-10 39.2 0.2 1.9e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 EEA05691.1 - 2.9e-09 36.1 0.2 0.00011 21.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEA05691.1 - 1e-06 28.6 0.0 2.5e-06 27.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EEA05691.1 - 1.2e-06 28.2 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA05691.1 - 1.2e-06 28.7 0.0 8.5e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA05691.1 - 1.5e-05 24.7 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEA05691.1 - 1.5e-05 24.1 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EEA05691.1 - 2.2e-05 24.4 0.0 0.00012 22.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EEA05691.1 - 3.7e-05 23.4 0.0 8.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEA05691.1 - 0.00014 20.9 0.0 0.00039 19.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA05691.1 - 0.00083 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EEA05691.1 - 0.0039 17.5 0.1 0.005 17.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEA05691.1 - 0.0045 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EEA05691.1 - 0.0054 17.5 0.1 0.024 15.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EEA05691.1 - 0.0063 15.9 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EEA05691.1 - 0.0081 16.2 0.0 6.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_10 PF12846.2 EEA05691.1 - 0.014 14.8 0.1 2.6 7.3 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EEA05691.1 - 0.021 15.0 0.0 0.064 13.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 EEA05691.1 - 0.023 14.5 0.0 0.17 11.7 0.0 2.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DNA_pol3_delta PF06144.8 EEA05691.1 - 0.027 13.9 0.5 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_24 PF13479.1 EEA05691.1 - 0.029 13.9 0.2 0.069 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEA05691.1 - 0.035 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 EEA05691.1 - 0.037 13.5 0.0 1.9 7.9 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EEA05691.1 - 0.039 13.1 0.0 0.26 10.4 0.0 2.2 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EEA05691.1 - 0.039 12.6 0.0 0.7 8.5 0.0 2.6 1 1 1 2 2 2 0 TIP49 C-terminus PhoH PF02562.11 EEA05691.1 - 0.04 13.1 0.1 6.9 5.8 0.0 2.3 1 1 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EEA05691.1 - 0.044 13.2 0.0 0.16 11.4 0.0 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family 2C_adapt PF08793.5 EEA05691.1 - 0.044 13.6 0.5 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 2-cysteine adaptor domain SNF2_N PF00176.18 EEA05691.1 - 0.05 12.3 0.1 0.29 9.8 0.0 1.9 1 1 1 2 2 2 0 SNF2 family N-terminal domain AAA_33 PF13671.1 EEA05691.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEA05691.1 - 0.063 12.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_3 PF07726.6 EEA05691.1 - 0.12 12.0 0.0 0.43 10.1 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Lung_7-TM_R PF06814.8 EEA05692.1 - 1.2e-45 155.7 30.6 1.6e-45 155.3 21.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor FixQ PF05545.6 EEA05692.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ MIF4G PF02854.14 EEA05693.1 - 8.2e-28 97.2 8.0 2.2e-27 95.8 5.5 1.8 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EEA05693.1 - 4.1e-18 65.1 0.2 2.5e-17 62.5 0.1 2.5 1 0 0 1 1 1 1 MA3 domain LOH1CR12 PF10158.4 EEA05693.1 - 0.067 12.9 1.7 0.47 10.2 0.1 2.6 2 0 0 2 2 2 0 Tumour suppressor protein Proteasome PF00227.21 EEA05695.1 - 9.1e-25 87.0 0.5 1.7e-24 86.1 0.4 1.4 1 1 0 1 1 1 1 Proteasome subunit ECR1_N PF14382.1 EEA05696.1 - 7.2e-10 37.9 0.3 3.2e-09 35.9 0.0 2.1 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region EXS PF03124.9 EEA05698.1 - 3.7e-71 239.9 29.7 3.7e-71 239.9 20.6 1.7 2 0 0 2 2 2 1 EXS family SPX PF03105.14 EEA05698.1 - 4.2e-07 30.0 2.3 0.0053 16.5 0.3 2.3 2 0 0 2 2 2 2 SPX domain SMC_N PF02463.14 EEA05699.1 - 9.8e-21 73.9 0.0 4.4e-09 35.8 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA05699.1 - 2e-05 24.7 3.4 2e-05 24.7 2.3 6.1 2 1 4 6 6 6 2 AAA domain AAA_29 PF13555.1 EEA05699.1 - 0.0014 18.0 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA05699.1 - 0.0053 17.1 42.4 0.0053 17.1 29.4 5.8 2 2 2 4 4 4 1 AAA domain SbcCD_C PF13558.1 EEA05699.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EEA05699.1 - 0.079 12.7 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Reo_sigmaC PF04582.7 EEA05699.1 - 6.1 5.9 32.7 0.34 10.0 3.2 4.6 3 2 1 5 5 5 0 Reovirus sigma C capsid protein Thioredoxin_2 PF13098.1 EEA05701.1 - 0.05 13.8 0.4 0.091 12.9 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Aa_trans PF01490.13 EEA05702.1 - 8.7e-08 31.0 37.9 8.7e-08 31.0 26.3 2.2 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Corona_S2 PF01601.11 EEA05703.1 - 0.018 13.1 0.4 0.033 12.3 0.3 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1077 PF06417.7 EEA05705.1 - 2e-28 98.2 2.1 2.6e-28 97.8 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RIC3 PF15361.1 EEA05705.1 - 0.12 12.6 0.6 2.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Cbl_N PF02262.11 EEA05706.1 - 0.0068 16.1 3.2 0.0068 16.1 2.2 2.5 2 1 0 2 2 2 1 CBL proto-oncogene N-terminal domain 1 NifU_N PF01592.11 EEA05707.1 - 6.4e-46 155.4 0.1 8.1e-46 155.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Rpr2 PF04032.11 EEA05708.1 - 2.8e-13 49.5 7.1 6e-13 48.4 4.9 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain IF4E PF01652.13 EEA05710.1 - 2.3e-40 137.8 0.3 3e-40 137.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PP2C PF00481.16 EEA05711.1 - 4.4e-15 55.7 0.6 5.1e-06 26.0 0.1 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 EEA05711.1 - 9.1e-06 25.2 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C SPRY PF00622.23 EEA05712.1 - 4.7e-18 65.4 0.3 8.5e-18 64.6 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EEA05712.1 - 1.2e-05 25.0 0.3 1.2e-05 25.0 0.2 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF4548 PF15081.1 EEA05713.1 - 0.14 11.7 1.6 0.22 11.0 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4548) RRM_1 PF00076.17 EEA05714.1 - 5e-19 67.7 0.0 8.4e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EEA05714.1 - 1.3e-16 60.6 0.1 3.6e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 EEA05714.1 - 1.3e-14 53.8 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05714.1 - 6.4e-09 35.5 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 EEA05715.1 - 4e-10 40.2 0.8 1.1e-09 38.7 0.5 1.8 1 0 0 1 1 1 1 SET domain Pkinase PF00069.20 EEA05716.1 - 2e-40 138.5 0.8 2.5e-40 138.2 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05716.1 - 1.5e-19 70.0 0.1 2.6e-19 69.3 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05716.1 - 0.0047 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA05716.1 - 0.015 14.3 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA05716.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA05716.1 - 0.099 12.1 1.6 0.21 11.1 1.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1e PF01406.14 EEA05717.1 - 4.8e-123 410.1 0.0 6.6e-123 409.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEA05717.1 - 2e-08 33.3 0.1 0.002 16.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEA05717.1 - 0.00019 19.6 0.0 0.00071 17.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EEA05717.1 - 0.00084 18.1 0.0 0.042 12.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 EEA05717.1 - 0.00097 17.8 0.0 0.0022 16.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.6 EEA05717.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 DALR domain CRAL_TRIO PF00650.15 EEA05718.1 - 1.9e-25 89.2 0.1 4e-25 88.1 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA05718.1 - 1.8e-11 44.1 0.0 4.3e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA05718.1 - 2.2e-06 27.7 0.0 7.5e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Pescadillo_N PF06732.6 EEA05719.1 - 1.7e-96 322.7 4.3 1.7e-96 322.7 3.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EEA05719.1 - 1.6e-07 31.3 0.4 2.1e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RrnaAD PF00398.15 EEA05720.1 - 6.9e-50 169.5 0.0 9.5e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EEA05720.1 - 3.1e-10 39.8 0.0 5.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA05720.1 - 4.2e-09 36.4 0.0 7.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA05720.1 - 4.4e-09 36.9 0.0 7.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA05720.1 - 2.2e-06 28.0 0.0 4.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA05720.1 - 2e-05 24.9 0.0 3.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA05720.1 - 2.7e-05 23.3 0.0 6.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EEA05720.1 - 0.0003 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA05720.1 - 0.00084 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA05720.1 - 0.0012 18.4 0.0 0.0032 17.0 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EEA05720.1 - 0.0017 17.4 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 EEA05720.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase UPF0020 PF01170.13 EEA05720.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF43 PF01861.11 EEA05720.1 - 0.078 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF43 LCM PF04072.9 EEA05720.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase AAA PF00004.24 EEA05721.1 - 2.3e-43 147.5 0.0 4.3e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEA05721.1 - 2.7e-07 30.6 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA05721.1 - 1.3e-06 28.1 0.1 4.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA05721.1 - 3.8e-06 27.0 0.3 0.00019 21.5 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA05721.1 - 6.9e-06 26.1 0.1 3e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEA05721.1 - 6.1e-05 23.8 0.2 0.00021 22.0 0.1 2.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEA05721.1 - 0.00013 21.0 0.0 0.00027 20.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA05721.1 - 0.00014 21.5 0.1 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEA05721.1 - 0.00038 19.9 0.0 0.00092 18.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEA05721.1 - 0.00093 18.0 0.0 0.0022 16.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEA05721.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA05721.1 - 0.0019 17.6 0.1 0.07 12.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA05721.1 - 0.0021 18.3 0.1 0.012 15.8 0.0 2.4 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 EEA05721.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEA05721.1 - 0.0038 16.3 0.8 0.023 13.8 0.0 2.4 3 0 0 3 3 3 1 KaiC NACHT PF05729.7 EEA05721.1 - 0.0038 16.9 0.0 0.58 9.7 0.0 2.5 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 EEA05721.1 - 0.0039 17.1 0.1 0.0082 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA05721.1 - 0.0043 16.1 0.0 0.0088 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EEA05721.1 - 0.0059 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EEA05721.1 - 0.0061 15.7 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EEA05721.1 - 0.0097 15.1 0.1 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.17 EEA05721.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EEA05721.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEA05721.1 - 0.031 13.1 0.2 0.17 10.6 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain Parvo_NS1 PF01057.12 EEA05721.1 - 0.038 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EEA05721.1 - 0.047 13.1 2.0 0.11 11.9 0.0 2.5 3 1 0 3 3 3 0 Sigma-54 interaction domain HR1 PF02185.11 EEA05721.1 - 0.047 13.4 1.9 0.18 11.5 1.3 2.0 1 0 0 1 1 1 0 Hr1 repeat Sigma54_activ_2 PF14532.1 EEA05721.1 - 0.059 13.4 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain SlyX PF04102.7 EEA05721.1 - 0.091 13.1 2.0 0.19 12.1 0.4 2.2 2 0 0 2 2 2 0 SlyX Sec20 PF03908.8 EEA05722.1 - 5.7e-08 32.3 2.7 7.1e-08 32.0 1.9 1.1 1 0 0 1 1 1 1 Sec20 YpjP PF14005.1 EEA05722.1 - 0.0066 16.2 0.1 0.0079 15.9 0.0 1.1 1 0 0 1 1 1 1 YpjP-like protein Paralemmin PF03285.10 EEA05722.1 - 0.038 13.4 1.6 0.041 13.3 1.1 1.1 1 0 0 1 1 1 0 Paralemmin TMEM247 PF15444.1 EEA05722.1 - 0.043 13.6 2.8 0.051 13.3 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 Tweety PF04906.8 EEA05722.1 - 0.08 11.3 0.5 0.088 11.2 0.4 1.0 1 0 0 1 1 1 0 Tweety IcmL PF11393.3 EEA05722.1 - 0.11 12.4 0.6 0.14 12.0 0.4 1.2 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein Med28 PF11594.3 EEA05722.1 - 0.68 10.1 4.1 0.73 10.1 2.0 1.7 2 1 0 2 2 2 0 Mediator complex subunit 28 Peptidase_C78 PF07910.8 EEA05723.1 - 5.1e-38 130.3 2.5 8e-38 129.7 1.8 1.3 1 0 0 1 1 1 1 Peptidase family C78 Shugoshin_C PF07557.6 EEA05724.1 - 0.025 14.0 0.3 0.025 14.0 0.2 2.5 2 0 0 2 2 2 0 Shugoshin C terminus Shugoshin_N PF07558.6 EEA05724.1 - 0.23 11.1 4.4 0.43 10.3 0.5 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region hDGE_amylase PF14701.1 EEA05725.1 - 1.6e-122 409.4 2.4 2e-122 409.1 1.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EEA05725.1 - 1.8e-105 352.7 0.2 2.9e-105 352.0 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EEA05725.1 - 3.8e-48 163.9 0.3 9.5e-48 162.6 0.2 1.7 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme DUF410 PF04190.8 EEA05726.1 - 2.4e-20 73.1 0.1 3e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SIP1 PF04938.7 EEA05727.1 - 0.11 11.8 3.2 0.27 10.5 2.2 1.8 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Thioredoxin PF00085.15 EEA05728.1 - 3.2e-22 78.1 1.1 6.9e-21 73.8 0.8 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EEA05728.1 - 3.1e-05 24.1 0.6 7.7e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EEA05728.1 - 0.00046 19.7 0.1 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EEA05728.1 - 0.032 14.2 0.1 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 EEA05728.1 - 0.046 13.8 4.7 0.11 12.5 0.7 3.6 2 1 1 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.16 EEA05728.1 - 0.052 13.2 0.3 0.18 11.4 0.2 1.9 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EEA05728.1 - 0.09 12.3 0.1 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 Redoxin Peptidase_A22B PF04258.8 EEA05729.1 - 3.4e-67 227.0 13.6 3.4e-67 227.0 9.4 1.3 2 0 0 2 2 2 1 Signal peptide peptidase Presenilin PF01080.12 EEA05729.1 - 0.015 14.1 2.3 0.015 14.1 1.6 2.1 3 0 0 3 3 3 0 Presenilin PrgI PF12666.2 EEA05729.1 - 0.025 14.7 1.1 0.025 14.7 0.7 4.0 3 1 2 5 5 5 0 PrgI family protein PH PF00169.24 EEA05730.1 - 1.3e-06 28.5 0.1 0.00043 20.4 0.0 3.8 3 0 0 3 3 3 1 PH domain PH_8 PF15409.1 EEA05730.1 - 0.00036 20.5 0.0 0.0013 18.7 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EEA05730.1 - 0.0011 19.0 0.0 0.0054 16.7 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Baculo_PEP_C PF04513.7 EEA05731.1 - 2.5e-05 24.1 5.7 0.014 15.2 1.2 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Relaxase PF03432.9 EEA05731.1 - 0.031 13.6 2.1 0.056 12.8 1.4 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain TEX13 PF15186.1 EEA05731.1 - 0.057 12.9 7.1 0.027 14.0 3.3 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family WXG100 PF06013.7 EEA05731.1 - 0.095 12.7 3.9 0.17 11.9 0.1 2.9 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Med4 PF10018.4 EEA05731.1 - 0.12 11.7 12.8 0.23 10.8 2.7 2.9 2 2 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1664 PF07889.7 EEA05731.1 - 0.14 11.9 10.1 0.9 9.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EEA05731.1 - 0.23 11.7 10.6 0.13 12.5 0.3 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EEA05731.1 - 0.45 10.4 18.6 0.68 9.8 7.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 EEA05731.1 - 0.5 10.0 16.9 1.9 8.1 0.2 3.4 3 0 0 3 3 3 0 Prefoldin subunit DUF4446 PF14584.1 EEA05731.1 - 1.1 9.0 4.7 1.5 8.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PEP-utilisers_N PF05524.8 EEA05731.1 - 2.2 8.0 5.6 1.3 8.8 0.2 2.6 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Fib_alpha PF08702.5 EEA05731.1 - 2.5 8.2 12.4 8 6.5 0.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 EEA05731.1 - 4.2 7.4 11.1 22 5.0 5.0 3.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase IncA PF04156.9 EEA05731.1 - 4.3 6.8 11.5 17 4.9 0.3 3.0 2 1 1 3 3 3 0 IncA protein Bap31 PF05529.7 EEA05731.1 - 5.4 6.4 9.4 16 4.8 4.1 2.3 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like BLOC1_2 PF10046.4 EEA05731.1 - 5.7 7.1 13.5 8.8 6.5 0.1 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EEA05731.1 - 8.4 5.9 11.8 28 4.2 0.6 3.4 3 0 0 3 3 3 0 Septum formation initiator FHA PF00498.21 EEA05732.1 - 2.9e-05 24.0 0.0 6.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain TSP_1 PF00090.14 EEA05733.1 - 1.8e-27 95.1 26.8 5e-09 36.1 6.0 3.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.22 EEA05733.1 - 9.7e-05 22.2 6.9 9.7e-05 22.2 4.8 3.0 3 0 0 3 3 3 1 EGF-like domain TSP_1 PF00090.14 EEA05734.1 - 1.1e-12 47.8 42.1 4.5e-07 29.8 3.7 4.0 3 1 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.22 EEA05734.1 - 0.00047 20.0 13.6 0.00047 20.0 9.4 4.1 4 1 0 4 4 4 1 EGF-like domain EGF_2 PF07974.8 EEA05734.1 - 0.00066 19.7 10.5 0.00066 19.7 7.3 3.3 3 1 0 3 3 3 1 EGF-like domain hEGF PF12661.2 EEA05734.1 - 0.004 17.1 1.8 0.019 15.0 1.2 2.3 1 0 0 1 1 1 1 Human growth factor-like EGF APC_CDC26 PF10471.4 EEA05736.1 - 0.0032 18.1 3.8 0.0096 16.6 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Rhomboid PF01694.17 EEA05737.1 - 4.3e-27 94.9 16.5 4.3e-27 94.9 11.5 1.8 3 0 0 3 3 3 1 Rhomboid family LRR_4 PF12799.2 EEA05738.1 - 3.6e-43 144.5 82.9 1.4e-09 37.3 3.9 6.8 3 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA05738.1 - 3.4e-27 93.9 74.5 1.8e-09 37.2 2.0 5.7 2 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.1 EEA05738.1 - 1.9e-14 53.6 21.1 8.3e-05 22.2 3.5 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EEA05738.1 - 2.4e-13 48.1 50.3 0.082 12.9 0.0 11.7 11 1 1 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 EEA05738.1 - 3.8e-10 38.2 34.0 1.2 9.6 0.1 11.5 11 1 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 EEA05738.1 - 2.2e-08 33.3 44.5 0.18 12.0 0.1 11.3 8 4 4 12 12 12 5 Leucine Rich repeat LRR_2 PF07723.8 EEA05738.1 - 2.1 8.9 14.8 48 4.6 0.1 6.9 9 0 0 9 9 9 0 Leucine Rich Repeat bZIP_2 PF07716.10 EEA05739.1 - 0.00011 21.9 8.0 0.00011 21.9 5.6 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EEA05739.1 - 0.0017 18.2 5.2 0.0017 18.2 3.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor DUF4618 PF15397.1 EEA05739.1 - 0.16 11.3 10.2 0.1 11.9 5.5 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.4 EEA05739.1 - 4.4 7.1 12.5 0.21 11.4 3.9 2.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EEA05739.1 - 7.6 6.0 11.9 1.8 8.1 3.9 2.0 1 1 1 2 2 2 0 IncA protein Cnd1 PF12717.2 EEA05740.1 - 4.7e-42 143.8 1.7 4.7e-42 143.8 1.2 5.1 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 E1-E2_ATPase PF00122.15 EEA05741.1 - 7.7e-19 67.6 0.0 6.9e-08 31.8 0.0 3.5 3 0 0 3 3 3 3 E1-E2 ATPase HAD PF12710.2 EEA05741.1 - 9.8e-17 61.7 0.0 2.5e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA05741.1 - 4.9e-13 49.9 0.0 3.6e-12 47.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA05741.1 - 0.0028 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEA05741.1 - 0.02 14.3 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Ribonuc_red_sm PF00268.16 EEA05743.1 - 4.9e-29 101.2 11.1 1e-28 100.1 6.4 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 EEA05744.1 - 8.9e-106 352.9 1.4 1.1e-105 352.6 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain C2 PF00168.25 EEA05746.1 - 8.6e-05 22.3 0.0 0.00051 19.8 0.0 2.4 2 0 0 2 2 2 1 C2 domain Peptidase_C11 PF03415.9 EEA05747.1 - 1.8e-26 93.0 2.3 5.8e-26 91.3 1.6 1.9 1 1 0 1 1 1 1 Clostripain family EGF_3 PF12947.2 EEA05747.1 - 7.5e-15 54.6 27.8 4.5e-09 36.1 2.5 4.8 4 0 0 4 4 4 2 EGF domain EGF_CA PF07645.10 EEA05747.1 - 1.3e-10 41.0 37.7 1.1e-06 28.4 3.0 6.2 5 2 1 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 EEA05747.1 - 4.9e-09 35.6 22.8 0.002 17.6 0.5 5.2 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 EEA05747.1 - 1.1e-06 28.4 31.3 0.0039 17.1 1.5 4.6 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.2 EEA05747.1 - 0.035 14.1 11.8 2.5 8.3 0.3 4.4 3 0 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.1 EEA05747.1 - 0.049 13.7 35.0 0.068 13.2 2.1 5.5 4 1 2 6 6 6 0 Coagulation Factor Xa inhibitory site EB PF01683.13 EEA05747.1 - 2 8.5 26.8 0.82 9.7 0.9 4.6 4 1 0 4 4 4 0 EB module Asp PF00026.18 EEA05748.1 - 1.9e-53 181.7 0.0 3.6e-53 180.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA05748.1 - 5e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EEA05748.1 - 0.0033 16.9 0.0 0.028 13.9 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Pkinase PF00069.20 EEA05749.1 - 4.9e-78 261.8 0.7 3.1e-77 259.2 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05749.1 - 3.6e-40 137.6 0.0 7.4e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05749.1 - 8.6e-07 28.1 0.0 3e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEA05749.1 - 0.0062 15.9 0.1 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EEA05749.1 - 0.043 13.5 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEA05749.1 - 0.056 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2691 PF10903.3 EEA05749.1 - 0.21 11.4 8.0 0.56 10.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2691) Mic1 PF07035.7 EEA05750.1 - 1.1e-06 28.0 5.1 1.1e-06 28.0 3.6 3.0 2 1 0 3 3 3 1 Colon cancer-associated protein Mic1-like Got1 PF04178.7 EEA05751.1 - 3.3e-27 94.9 20.4 4.2e-27 94.5 14.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.11 EEA05751.1 - 0.028 13.1 14.8 0.033 12.9 10.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Pkinase PF00069.20 EEA05752.1 - 7.7e-60 202.2 0.0 9e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05752.1 - 8.3e-21 74.2 0.0 1.1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA05752.1 - 2.3e-07 30.8 0.1 7.1e-06 25.9 0.1 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA05752.1 - 0.0053 16.3 1.0 0.031 13.8 0.1 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EEA05752.1 - 0.046 12.7 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.11 EEA05752.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family ATP-synt_ab PF00006.20 EEA05753.1 - 1e-72 244.1 0.0 1.5e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA05753.1 - 4.4e-21 75.4 2.1 1.6e-20 73.6 0.8 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA05753.1 - 6.1e-21 74.4 2.1 1.7e-20 73.0 1.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA05753.1 - 3.2e-07 30.1 2.0 3.2e-07 30.1 1.4 2.0 2 0 0 2 2 2 1 HAS barrel domain Miro PF08477.8 EEA05753.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Gp37 PF09646.5 EEA05754.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Gp37 protein DUF3608 PF12257.3 EEA05755.1 - 7.2e-14 51.3 3.7 1.2e-06 27.6 0.3 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3608) Beta-Casp PF10996.3 EEA05756.1 - 7e-21 74.4 0.0 2.2e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Sterile PF03015.14 EEA05756.1 - 0.082 13.1 0.1 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Male sterility protein Ribosomal_L14 PF00238.14 EEA05757.1 - 6.4e-34 116.3 0.0 7.2e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_2c PF01411.14 EEA05758.1 - 9.9e-192 638.0 0.0 1.5e-191 637.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEA05758.1 - 2.7e-15 55.9 0.3 2.7e-15 55.9 0.2 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain LsmAD PF06741.8 EEA05758.1 - 0.014 15.4 0.3 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 LsmAD domain AAA PF00004.24 EEA05759.1 - 9e-32 110.0 0.0 1.6e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA05759.1 - 2.7e-06 27.5 0.0 6.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA05759.1 - 2e-05 25.3 0.4 8.4e-05 23.3 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EEA05759.1 - 0.00081 19.6 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA05759.1 - 0.00089 19.2 0.1 0.0025 17.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EEA05759.1 - 0.0016 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EEA05759.1 - 0.0042 16.1 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 EEA05759.1 - 0.0053 15.8 0.1 0.065 12.2 0.0 2.0 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 EEA05759.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 EEA05759.1 - 0.0079 15.9 0.1 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EEA05759.1 - 0.0091 15.7 0.6 0.25 11.0 0.4 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 EEA05759.1 - 0.0096 15.5 0.1 0.053 13.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EEA05759.1 - 0.011 14.8 0.3 2.4 7.2 0.0 2.4 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 EEA05759.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EEA05759.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 EEA05759.1 - 0.015 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EEA05759.1 - 0.018 14.4 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EEA05759.1 - 0.024 13.8 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EEA05759.1 - 0.024 14.2 0.1 0.14 11.8 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EEA05759.1 - 0.025 14.4 0.0 0.049 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EEA05759.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_28 PF13521.1 EEA05759.1 - 0.032 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EEA05759.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EEA05759.1 - 0.041 14.0 0.1 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.11 EEA05759.1 - 0.057 12.6 0.0 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EEA05759.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EEA05759.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 EEA05759.1 - 0.087 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EEA05759.1 - 0.09 12.3 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EEA05759.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RWD PF05773.17 EEA05760.1 - 0.00055 19.8 0.0 0.0034 17.2 0.0 2.5 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.20 EEA05761.1 - 1.1e-70 237.8 0.0 1.8e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05761.1 - 6e-37 127.1 0.0 9.1e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA05761.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA05761.1 - 0.19 11.4 0.1 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Synaptobrevin PF00957.16 EEA05762.1 - 2.9e-15 55.6 0.5 4.5e-15 55.0 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEA05762.1 - 3.5e-07 29.6 0.0 5.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain CotJB PF12652.2 EEA05762.1 - 0.83 9.7 3.2 0.29 11.2 0.4 1.6 2 0 0 2 2 2 0 CotJB protein PDEase_I PF00233.14 EEA05763.1 - 1.6e-49 168.7 10.8 6.4e-35 121.0 6.6 2.5 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Zip PF02535.17 EEA05764.1 - 3.9e-31 108.2 17.5 4.9e-31 107.8 12.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4131 PF13567.1 EEA05764.1 - 1.9 7.8 6.1 0.12 11.7 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Acatn PF13000.2 EEA05766.1 - 6.7e-64 216.3 29.1 8.9e-63 212.6 20.2 1.9 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 EEA05766.1 - 2.5e-11 42.9 14.6 2.5e-11 42.9 10.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily BSD PF03909.12 EEA05767.1 - 4.1e-11 42.4 0.2 4.5e-09 35.9 0.0 3.0 2 0 0 2 2 2 2 BSD domain Vps36_ESCRT-II PF11605.3 EEA05767.1 - 0.024 14.4 1.9 0.19 11.5 0.0 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 PP2C PF00481.16 EEA05768.1 - 2.2e-17 63.2 0.6 3.8e-15 55.9 0.0 3.5 2 1 0 2 2 2 1 Protein phosphatase 2C Polysacc_synt_C PF14667.1 EEA05769.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF1573 PF07610.6 EEA05769.1 - 0.61 9.7 3.1 0.95 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) RRM_1 PF00076.17 EEA05771.1 - 2.9e-17 62.0 0.0 5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05771.1 - 3.7e-16 58.8 0.0 6.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05771.1 - 1e-09 38.0 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fip1 PF05182.8 EEA05772.1 - 2.8e-10 39.2 0.2 4.8e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Fip1 motif COPI_assoc PF08507.5 EEA05774.1 - 7.5e-14 51.5 24.1 1.5e-13 50.5 16.7 1.6 1 1 0 1 1 1 1 COPI associated protein SLAP PF03217.9 EEA05774.1 - 0.068 13.3 2.5 0.1 12.8 1.7 1.2 1 0 0 1 1 1 0 Bacterial surface layer protein Cg6151-P PF10233.4 EEA05774.1 - 0.36 10.8 15.1 7 6.6 10.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P SelP_N PF04592.9 EEA05774.1 - 1.7 7.9 13.6 2.6 7.3 9.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region WD40 PF00400.27 EEA05775.1 - 4.8e-08 32.5 15.8 0.00037 20.2 1.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF775 PF05603.7 EEA05776.1 - 7.1e-29 100.7 0.4 2.2e-27 95.8 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Vps36_ESCRT-II PF11605.3 EEA05777.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 EEA05777.1 - 0.0054 16.9 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Mg_trans_NIPA PF05653.9 EEA05778.1 - 1.2e-11 44.1 22.1 9.5e-09 34.6 6.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EEA05778.1 - 1.2e-06 28.5 11.0 1.2e-06 28.5 7.6 3.7 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EEA05778.1 - 2.4e-05 24.4 5.7 2.4e-05 24.4 3.9 2.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter MgtE_N PF03448.12 EEA05779.1 - 0.0013 19.0 3.3 0.0021 18.3 1.3 2.0 1 1 1 2 2 2 1 MgtE intracellular N domain CCP_MauG PF03150.9 EEA05779.1 - 0.0066 16.7 0.4 1.2 9.4 0.3 2.1 1 1 0 1 1 1 1 Di-haem cytochrome c peroxidase ACCA PF03255.9 EEA05779.1 - 0.49 9.9 2.5 3.9 6.9 0.4 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PyrI PF01948.13 EEA05782.1 - 0.075 13.0 4.8 0.64 10.0 0.2 3.5 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain CLTH PF10607.4 EEA05783.1 - 0.00033 20.3 6.3 0.00033 20.3 4.4 2.4 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEA05783.1 - 0.00039 20.0 0.0 0.0016 18.0 0.0 2.2 1 0 0 1 1 1 1 RING-type zinc-finger Adaptin_N PF01602.15 EEA05784.1 - 1.1e-60 205.4 23.8 1.7e-60 204.8 16.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EEA05784.1 - 3.6e-41 139.9 0.3 1.3e-40 138.1 0.2 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EEA05784.1 - 5.3e-30 103.9 0.4 1.4e-29 102.5 0.3 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EEA05784.1 - 6.3e-06 26.3 0.1 0.0029 17.8 0.0 3.7 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EEA05784.1 - 0.013 15.5 0.0 0.68 10.1 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat DAGAT PF03982.8 EEA05785.1 - 1.1e-26 93.2 0.0 1.6e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TatD_DNase PF01026.16 EEA05786.1 - 4.3e-33 114.5 0.0 4.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DUF2099 PF09872.4 EEA05786.1 - 0.12 11.4 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) MCM PF00493.18 EEA05787.1 - 4.7e-132 439.8 2.1 7.1e-132 439.2 1.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA05787.1 - 2.1e-15 57.3 0.2 1.2e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA05787.1 - 3.5e-06 26.3 0.0 1.4e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA05787.1 - 1.9e-05 24.4 0.0 3.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EEA05787.1 - 0.026 14.9 0.8 0.15 12.5 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Desulfoferrod_N PF06397.7 EEA05787.1 - 0.24 10.8 2.2 0.55 9.6 1.5 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain APG6 PF04111.7 EEA05788.1 - 2.9e-58 197.3 9.9 2.9e-58 197.3 6.9 2.2 2 1 0 2 2 2 1 Autophagy protein Apg6 zf-AD PF07776.10 EEA05788.1 - 0.26 11.3 7.6 0.77 9.8 5.3 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) G-patch_2 PF12656.2 EEA05789.1 - 8.3e-13 47.9 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EEA05789.1 - 0.21 11.4 0.9 0.3 10.9 0.1 1.6 2 0 0 2 2 2 0 G-patch domain Apc15p PF05841.6 EEA05789.1 - 2.9 8.6 9.3 0.089 13.5 1.2 2.2 2 1 1 3 3 3 0 Apc15p protein DUF4587 PF15248.1 EEA05791.1 - 0.029 14.9 9.3 1 9.9 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) cEGF PF12662.2 EEA05791.1 - 0.95 9.1 6.9 28 4.4 0.0 4.6 5 0 0 5 5 5 0 Complement Clr-like EGF-like Tme5_EGF_like PF09064.5 EEA05791.1 - 1.3 8.7 14.1 5.7 6.6 0.1 4.9 5 0 0 5 5 5 0 Thrombomodulin like fifth domain, EGF-like PH_11 PF15413.1 EEA05792.1 - 1e-05 25.7 1.6 4.6e-05 23.6 1.1 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEA05792.1 - 5.2e-05 23.4 2.6 5.2e-05 23.4 1.8 2.3 2 0 0 2 2 2 1 PH domain TFIIA PF03153.8 EEA05793.1 - 0.0019 18.1 13.9 0.0041 17.0 6.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.12 EEA05793.1 - 1 8.0 3.2 1.3 7.7 2.2 1.1 1 0 0 1 1 1 0 Presenilin Synaptobrevin PF00957.16 EEA05794.1 - 2.3e-18 65.5 0.5 2.3e-18 65.5 0.3 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EEA05794.1 - 2.8e-14 52.4 0.4 6.8e-14 51.1 0.3 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sipho_Gp157 PF05565.6 EEA05794.1 - 0.063 12.8 1.6 1.9 8.0 0.3 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 HARP PF07443.8 EEA05794.1 - 0.081 12.3 0.1 0.081 12.3 0.1 2.8 3 0 0 3 3 3 0 HepA-related protein (HARP) DUF3782 PF12644.2 EEA05795.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) GLTSCR1 PF15249.1 EEA05796.1 - 6.8e-06 26.1 0.1 1.2e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region DNA_Packaging_2 PF11123.3 EEA05796.1 - 0.053 13.3 0.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 DNA packaging protein DUF4298 PF14131.1 EEA05796.1 - 1.2 9.0 6.4 5.1 7.0 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) Na_H_Exchanger PF00999.16 EEA05797.1 - 3.3e-46 157.5 37.6 4.5e-46 157.0 26.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 EEA05798.1 - 1.3e-51 175.2 38.5 1.8e-51 174.8 26.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Thioredoxin PF00085.15 EEA05799.1 - 2.5e-56 187.7 0.1 4.1e-27 93.8 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA05799.1 - 3.4e-22 79.1 2.3 3.3e-11 43.3 0.1 3.9 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEA05799.1 - 6.5e-14 52.0 3.7 1.4e-08 34.8 0.1 4.3 3 3 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEA05799.1 - 1.2e-09 38.0 0.3 0.0013 18.7 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EEA05799.1 - 1.2e-09 38.1 0.2 0.018 15.1 0.0 4.9 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 EEA05799.1 - 8.5e-06 25.4 0.8 0.12 12.0 0.0 2.7 2 1 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EEA05799.1 - 1.6e-05 24.8 0.0 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 1 ERp29, N-terminal domain Redoxin PF08534.5 EEA05799.1 - 0.00016 21.2 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EEA05799.1 - 0.0014 18.2 0.0 1.1 8.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EEA05799.1 - 0.0024 17.6 0.6 0.59 9.9 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin domain Calsequestrin PF01216.12 EEA05799.1 - 0.0035 16.1 0.0 0.0058 15.4 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_5 PF13743.1 EEA05799.1 - 0.079 12.5 1.3 12 5.3 0.1 3.1 2 1 1 3 3 3 0 Thioredoxin TraF PF13728.1 EEA05799.1 - 0.1 12.0 0.0 15 4.9 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein Malectin PF11721.3 EEA05800.1 - 5.2e-23 81.6 0.4 6.8e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 Di-glucose binding within endoplasmic reticulum Citrate_synt PF00285.16 EEA05801.1 - 7.2e-123 409.8 0.0 8.4e-123 409.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase LRR_4 PF12799.2 EEA05802.1 - 3.2e-23 80.8 65.1 6.1e-09 35.2 5.0 6.0 4 2 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA05802.1 - 5.6e-18 64.4 56.5 7.7e-09 35.1 7.7 4.9 2 2 3 5 5 5 5 Leucine rich repeat LRR_7 PF13504.1 EEA05802.1 - 3.6e-10 38.3 34.2 0.066 13.4 0.4 9.8 9 0 0 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 EEA05802.1 - 5.7e-08 31.7 55.2 0.16 12.1 1.1 9.5 9 1 1 10 10 10 7 Leucine Rich Repeat LRR_6 PF13516.1 EEA05802.1 - 1.4e-05 24.6 49.3 0.067 13.2 0.6 9.7 7 2 3 10 10 10 4 Leucine Rich repeat Binary_toxB PF03495.9 EEA05802.1 - 0.0035 16.0 1.2 0.0053 15.4 0.8 1.2 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA RE_AccI PF09545.5 EEA05802.1 - 1.1 7.7 7.4 0.6 8.6 2.4 2.2 2 1 1 3 3 3 0 AccI restriction endonuclease MS_channel PF00924.13 EEA05803.1 - 8.7e-18 64.3 1.7 1.6e-17 63.5 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Hist_deacetyl PF00850.14 EEA05804.1 - 3.1e-78 263.2 0.0 3.9e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_M48 PF01435.13 EEA05805.1 - 6.8e-30 104.3 0.0 9.4e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.4 EEA05805.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Aminotran_3 PF00202.16 EEA05806.1 - 5.7e-88 295.0 0.0 7e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EEA05806.1 - 2.4e-33 115.4 0.0 3.9e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EEA05806.1 - 1.2e-05 24.7 0.1 2.8e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EEA05806.1 - 0.0098 16.7 0.0 0.064 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Aminotran_1_2 PF00155.16 EEA05806.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pox_A28 PF04584.9 EEA05808.1 - 0.021 14.7 1.9 0.039 13.8 1.3 1.4 1 1 0 1 1 1 0 Poxvirus A28 family Secretin_N_2 PF07655.8 EEA05808.1 - 0.45 10.9 8.7 0.66 10.4 6.0 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Dzip-like_N PF13815.1 EEA05809.1 - 0.0021 17.8 0.3 0.0023 17.7 0.2 1.2 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Pox_A_type_inc PF04508.7 EEA05809.1 - 0.25 11.2 1.1 0.44 10.4 0.2 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IncA PF04156.9 EEA05809.1 - 0.74 9.3 5.3 1.5 8.4 3.7 1.5 1 1 0 1 1 1 0 IncA protein GrpE PF01025.14 EEA05811.1 - 5e-47 159.5 0.3 6.2e-47 159.2 0.2 1.1 1 0 0 1 1 1 1 GrpE Tropomyosin_1 PF12718.2 EEA05811.1 - 0.0072 16.1 5.1 0.013 15.3 3.6 1.3 1 0 0 1 1 1 1 Tropomyosin like Mating_N PF12731.2 EEA05811.1 - 0.019 14.8 0.5 0.035 13.9 0.3 1.5 1 1 0 1 1 1 0 Mating-type protein beta 1 DUF267 PF03268.9 EEA05811.1 - 0.041 12.7 0.1 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DUF1908 PF08926.6 EEA05811.1 - 0.061 12.0 0.4 0.088 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) UPF0118 PF01594.11 EEA05811.1 - 0.061 12.2 0.2 0.2 10.6 0.2 1.7 2 1 0 2 2 2 0 Domain of unknown function DUF20 DUF4591 PF15261.1 EEA05811.1 - 0.21 11.8 1.7 0.37 11.0 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) PMC2NT PF08066.7 EEA05811.1 - 0.37 11.1 5.6 11 6.3 2.4 3.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DnaJ PF00226.26 EEA05812.1 - 1.3e-09 37.6 0.1 1.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EEA05812.1 - 2.2e-05 24.2 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EEA05813.1 - 5.2e-27 93.3 0.6 9.6e-27 92.5 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain TFIIB PF00382.14 EEA05814.1 - 3.4e-25 87.6 0.2 3e-12 46.1 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEA05814.1 - 1.2e-09 37.3 1.8 2.9e-09 36.0 1.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding BRF1 PF07741.8 EEA05814.1 - 2.7e-09 37.0 4.9 2.7e-09 37.0 3.4 2.1 3 0 0 3 3 3 1 Brf1-like TBP-binding domain RRN7 PF11781.3 EEA05814.1 - 0.0037 16.7 0.3 0.0068 15.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EEA05814.1 - 0.01 15.0 1.0 0.039 13.1 0.6 2.0 1 1 1 2 2 2 2 zinc-ribbon domain HTH_24 PF13412.1 EEA05814.1 - 0.028 13.7 0.1 1.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding GLTP PF08718.6 EEA05815.1 - 1.2e-23 83.7 0.0 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Nol1_Nop2_Fmu PF01189.12 EEA05816.1 - 1e-27 97.2 0.0 4.8e-26 91.7 0.0 2.4 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 EEA05816.1 - 0.05 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEA05816.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NUC205 PF08168.6 EEA05816.1 - 0.074 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 NUC205 domain DUF1002 PF06207.6 EEA05816.1 - 2.7 7.2 4.6 0.37 10.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Patatin PF01734.17 EEA05817.1 - 9.6e-13 48.5 0.1 2.8e-12 47.0 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EEA05818.1 - 3.9e-13 49.8 0.0 8.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase GPS PF01825.16 EEA05819.1 - 0.0015 18.5 1.0 0.0054 16.8 0.7 1.9 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain ACT_7 PF13840.1 EEA05819.1 - 0.038 13.4 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 ACT domain BPL_N PF09825.4 EEA05820.1 - 4.7e-20 71.7 0.0 6.1e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal ThuA PF06283.6 EEA05820.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose utilisation 4HBT PF03061.17 EEA05821.1 - 3.8e-07 30.1 0.0 9.9e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily DTW PF03942.10 EEA05822.1 - 5.2e-09 35.6 0.0 6.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 DTW domain 5_nucleotid_C PF02872.13 EEA05823.1 - 9.2e-36 123.1 0.0 1.8e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEA05823.1 - 1.2e-08 34.5 0.6 2.4e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA05823.1 - 0.0038 17.0 0.0 0.0097 15.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAC PF01849.13 EEA05824.1 - 1.3e-15 56.6 1.3 2.8e-15 55.5 0.9 1.6 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EEA05824.1 - 8.2e-05 22.3 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF4263 PF14082.1 EEA05824.1 - 0.28 11.0 3.8 0.19 11.6 0.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4263) EBV-NA3 PF05009.7 EEA05824.1 - 1.8 7.7 6.9 0.18 10.9 0.3 2.0 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PKI PF02827.11 EEA05824.1 - 6 7.0 8.5 0.47 10.5 2.1 1.9 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DnaJ PF00226.26 EEA05825.1 - 2.1e-23 81.8 1.4 4.9e-23 80.6 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EEA05825.1 - 6.6e-17 61.7 0.6 6.6e-17 61.7 0.4 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 EEA05825.1 - 0.0018 18.0 0.0 0.0098 15.7 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA05825.1 - 0.016 14.8 0.4 0.059 13.0 0.0 2.1 2 0 0 2 2 2 0 TPR repeat OppC_N PF12911.2 EEA05825.1 - 0.053 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Semialdhyde_dh PF01118.19 EEA05825.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TPR_14 PF13428.1 EEA05825.1 - 0.11 13.2 0.0 0.37 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3169 PF11368.3 EEA05825.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) TSP_1 PF00090.14 EEA05826.1 - 8.3e-59 195.5 178.5 1.3e-10 41.1 3.5 16.6 17 0 0 17 17 17 12 Thrombospondin type 1 domain Notch PF00066.12 EEA05826.1 - 9.3e-41 137.8 181.5 2.3e-10 40.5 13.7 11.0 9 0 0 9 9 9 6 LNR domain ABC_cobalt PF09819.4 EEA05826.1 - 0.94 9.4 0.1 1.7 8.6 0.1 1.3 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component TPT PF03151.11 EEA05827.1 - 4.1e-21 75.2 16.9 4.1e-21 75.2 11.7 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEA05827.1 - 9.6e-10 37.8 32.6 1.5e-09 37.2 22.6 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEA05827.1 - 4.2e-07 30.0 39.3 2.2e-06 27.7 8.1 3.0 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EEA05827.1 - 0.12 12.5 30.5 0.088 13.0 3.3 3.4 2 2 1 3 3 3 0 Multidrug resistance efflux transporter Rep_2 PF01719.12 EEA05827.1 - 0.74 9.2 5.5 1.5 8.2 3.8 1.5 1 1 0 1 1 1 0 Plasmid replication protein Peptidase_M16 PF00675.15 EEA05828.1 - 1.7e-49 167.3 0.0 7.1e-49 165.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA05828.1 - 1.3e-31 109.7 0.1 5.5e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain SRR PF07709.6 EEA05828.1 - 0.08 13.1 0.5 18 6.0 0.0 2.9 2 0 0 2 2 2 0 Seven Residue Repeat Kazal_2 PF07648.10 EEA05830.1 - 3.2e-12 46.1 8.5 4.6e-07 29.6 3.2 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EEA05830.1 - 1.4e-10 41.0 7.5 7.3e-07 29.1 2.7 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Pentapeptide PF00805.17 EEA05830.1 - 0.36 10.1 2.6 0.93 8.8 0.1 2.6 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EEA05830.1 - 0.41 10.4 3.9 5.1 6.9 0.1 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) DUF1664 PF07889.7 EEA05831.1 - 2.8 7.7 13.1 0.65 9.8 0.4 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) ADK PF00406.17 EEA05832.1 - 7.3e-54 181.7 0.0 8.6e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EEA05832.1 - 2.9e-17 62.0 0.0 5.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EEA05832.1 - 8.9e-09 35.7 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA05832.1 - 2.9e-07 31.3 0.1 6.1e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA05832.1 - 1.3e-06 28.3 0.0 3.4e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA05832.1 - 0.00016 20.8 0.0 0.00042 19.4 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EEA05832.1 - 0.012 15.0 0.0 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 Thymidylate kinase RNA_helicase PF00910.17 EEA05832.1 - 0.012 15.7 0.0 2.1 8.5 0.0 2.3 1 1 0 2 2 2 0 RNA helicase 6PF2K PF01591.13 EEA05832.1 - 0.013 14.5 0.0 3.5 6.6 0.0 2.3 1 1 1 2 2 2 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 EEA05832.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA05832.1 - 0.091 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.16 EEA05833.1 - 1.3e-44 152.0 0.0 1.6e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lon_C PF05362.8 EEA05834.1 - 1.5e-63 213.8 0.0 5.8e-63 211.9 0.0 2.1 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEA05834.1 - 3e-25 89.1 0.4 3e-25 89.1 0.3 3.3 3 1 0 3 3 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEA05834.1 - 3.1e-23 82.4 1.0 1.3e-22 80.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EEA05834.1 - 4.8e-13 48.6 0.0 9.4e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EEA05834.1 - 3.8e-11 42.8 0.0 2.2e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA05834.1 - 9.1e-06 26.5 1.0 4.4e-05 24.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA05834.1 - 1.4e-05 25.0 8.8 0.00022 21.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EEA05834.1 - 1.9e-05 24.7 0.9 6e-05 23.1 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain BH3 PF15285.1 EEA05834.1 - 0.00026 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting AAA_22 PF13401.1 EEA05834.1 - 0.00069 19.7 5.4 0.0018 18.3 0.1 3.9 3 2 1 4 4 3 1 AAA domain AAA_10 PF12846.2 EEA05834.1 - 0.0027 17.1 0.0 0.0074 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_3 PF07726.6 EEA05834.1 - 0.0029 17.1 0.0 0.0075 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EEA05834.1 - 0.0032 17.7 0.0 0.0032 17.7 0.0 3.2 3 1 0 3 3 1 1 ABC transporter AAA_30 PF13604.1 EEA05834.1 - 0.0059 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EEA05834.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EEA05834.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EEA05834.1 - 0.0082 16.3 0.0 0.033 14.3 0.0 2.1 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 EEA05834.1 - 0.0096 15.5 0.0 0.034 13.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EEA05834.1 - 0.012 15.2 0.1 0.049 13.2 0.0 2.1 2 0 0 2 2 1 0 NACHT domain Zeta_toxin PF06414.7 EEA05834.1 - 0.014 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.14 EEA05834.1 - 0.023 13.9 0.1 0.023 13.9 0.0 2.3 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EEA05834.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EEA05834.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EEA05834.1 - 0.032 13.6 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EEA05834.1 - 0.05 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2142 PF09913.4 EEA05834.1 - 0.051 12.2 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) AAA_25 PF13481.1 EEA05834.1 - 0.054 12.8 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEA05834.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.5 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EEA05834.1 - 0.086 12.4 0.0 0.086 12.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EEA05834.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain vATP-synt_AC39 PF01992.11 EEA05835.1 - 2.9e-59 200.9 2.9 4.9e-59 200.1 2.0 1.4 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF2682 PF10909.3 EEA05835.1 - 0.048 13.9 0.3 0.24 11.7 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) DER1 PF04511.10 EEA05836.1 - 2.1e-45 154.6 17.9 2.4e-45 154.4 12.4 1.0 1 0 0 1 1 1 1 Der1-like family WD40 PF00400.27 EEA05838.1 - 7.7e-16 57.2 5.0 1.3e-05 24.8 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-HC5HC2H_2 PF13832.1 EEA05839.1 - 7.3e-18 64.5 50.0 5.6e-08 32.7 0.1 7.2 4 2 1 6 6 6 4 PHD-zinc-finger like domain PHD_2 PF13831.1 EEA05839.1 - 7.2e-07 28.4 19.8 2.2e-06 26.8 3.7 4.8 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H PF13771.1 EEA05839.1 - 4.3e-06 26.7 18.3 0.0002 21.4 4.9 7.4 7 2 2 9 9 9 2 PHD-like zinc-binding domain PHD PF00628.24 EEA05839.1 - 0.00045 19.8 9.1 0.00045 19.8 6.3 6.3 8 0 0 8 8 8 3 PHD-finger TFIIS_M PF07500.9 EEA05840.1 - 1.2e-15 57.5 3.5 1.6e-15 57.1 0.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain DUF1168 PF06658.7 EEA05841.1 - 1.3e-22 79.8 11.0 1.6e-22 79.5 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Fucose_iso_N2 PF07882.7 EEA05841.1 - 0.36 10.4 2.3 0.49 10.0 1.6 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain RRM_1 PF00076.17 EEA05842.1 - 2.5e-29 100.7 0.2 1.2e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05842.1 - 2.5e-25 88.2 0.1 1.7e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05842.1 - 8.2e-12 44.8 0.4 2e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_1 PF00054.18 EEA05842.1 - 0.0049 16.8 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 1 Laminin G domain Nup35_RRM PF05172.8 EEA05842.1 - 0.012 15.3 0.2 0.79 9.5 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EEA05842.1 - 0.022 14.2 0.3 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Laminin_G_2 PF02210.19 EEA05842.1 - 0.026 14.5 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain Spo7_2_N PF15407.1 EEA05842.1 - 0.06 12.8 0.1 0.81 9.2 0.0 2.4 3 0 0 3 3 3 0 Sporulation protein family 7 zf-Tim10_DDP PF02953.10 EEA05843.1 - 4.3e-10 38.7 0.6 5.1e-10 38.4 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EEA05843.1 - 0.029 13.8 0.8 0.033 13.6 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Cytomega_TRL10 PF06084.6 EEA05843.1 - 0.1 12.4 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Glyco_transf_8 PF01501.15 EEA05844.1 - 2e-33 115.7 4.1 2.5e-33 115.4 2.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Sod_Fe_C PF02777.13 EEA05845.1 - 5.2e-37 125.9 0.2 5.2e-37 125.9 0.1 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEA05845.1 - 1.6e-28 98.7 1.0 4.2e-28 97.4 0.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Proteasome PF00227.21 EEA05846.1 - 5.9e-14 51.7 0.7 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit SQS_PSY PF00494.14 EEA05847.1 - 0.27 10.4 0.0 0.49 9.6 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase AMP-binding PF00501.23 EEA05848.1 - 2.5e-63 213.9 0.0 3.3e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA05848.1 - 0.017 16.0 0.0 0.038 14.9 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Mito_carr PF00153.22 EEA05849.1 - 2.7e-33 113.5 0.3 6.4e-16 57.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane_5 PF13346.1 EEA05849.1 - 0.054 12.7 1.2 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Adenosine_kin PF04008.9 EEA05849.1 - 0.067 12.6 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Adenosine specific kinase Pkinase PF00069.20 EEA05850.1 - 1.8e-20 73.1 0.0 9.2e-07 28.2 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05850.1 - 8.3e-18 64.3 0.0 3.1e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SAM_1 PF00536.25 EEA05850.1 - 0.00018 21.6 0.1 0.00091 19.3 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEA05850.1 - 0.00023 20.9 0.0 0.00056 19.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MORN PF02493.15 EEA05850.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 MORN repeat Histone PF00125.19 EEA05851.1 - 2.9e-19 68.9 0.6 4e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA05851.1 - 4.1e-06 26.7 0.9 9.8e-06 25.5 0.6 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEA05851.1 - 0.0022 18.2 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF3825 PF12873.2 EEA05851.1 - 0.011 14.8 0.3 0.013 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) FAST_2 PF08368.7 EEA05851.1 - 0.048 14.0 0.7 0.48 10.8 0.1 2.0 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 PBC PF03792.8 EEA05851.1 - 0.06 13.0 1.3 0.083 12.5 0.9 1.3 1 1 0 1 1 1 0 PBC domain TAF PF02969.12 EEA05851.1 - 0.13 12.1 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Actin PF00022.14 EEA05852.1 - 1.1e-155 517.8 0.0 1.3e-155 517.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEA05852.1 - 0.029 14.7 0.1 0.12 12.8 0.0 1.9 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EEA05852.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Glycos_transf_1 PF00534.15 EEA05853.1 - 1.5e-39 135.1 0.0 3.9e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA05853.1 - 5.1e-18 65.5 0.0 1.1e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA05853.1 - 1.2e-17 64.5 0.0 2.9e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EEA05853.1 - 1e-13 51.3 0.1 2.4e-11 43.5 0.0 2.6 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.1 EEA05853.1 - 3.4e-09 36.6 0.9 4.4e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Alpha-amylase PF00128.19 EEA05853.1 - 7.4e-06 25.5 0.5 1.9e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EEA05853.1 - 3.3e-05 23.9 0.3 0.00015 21.8 0.2 2.2 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_trans_1_2 PF13524.1 EEA05853.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 TPR_11 PF13414.1 EEA05854.1 - 4.4e-11 42.2 0.6 3.1e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA05854.1 - 4.6e-06 25.9 0.1 0.007 15.9 0.0 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA05854.1 - 0.00049 19.8 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA05854.1 - 0.031 14.2 0.2 0.66 9.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA05854.1 - 0.11 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat VTC PF09359.5 EEA05857.1 - 4.5e-95 317.9 3.2 9.7e-95 316.8 2.2 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 EEA05857.1 - 4.1e-05 23.7 1.1 0.00028 21.0 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF202) SPX PF03105.14 EEA05857.1 - 0.0011 18.8 1.2 0.0011 18.8 0.8 2.5 4 0 0 4 4 4 1 SPX domain Abhydrolase_2 PF02230.11 EEA05858.1 - 3.5e-13 49.4 0.0 5.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA05858.1 - 6.6e-05 22.6 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEA05858.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA05858.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family TPR_15 PF13429.1 EEA05859.1 - 0.26 10.3 0.0 0.45 9.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TMA7 PF09072.5 EEA05862.1 - 5.5e-12 45.9 12.8 5.9e-12 45.8 8.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Herpes_IR6 PF06307.7 EEA05863.1 - 0.11 11.8 0.1 0.26 10.5 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus IR6 protein GTP_EFTU PF00009.22 EEA05864.1 - 2.9e-54 183.3 0.1 5.9e-54 182.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA05864.1 - 1.3e-35 121.5 0.3 3.4e-35 120.1 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA05864.1 - 1.9e-17 63.1 1.3 4.2e-17 62.0 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEA05864.1 - 1.7e-06 27.5 0.5 6.6e-06 25.6 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEA05864.1 - 0.00013 21.9 0.0 0.00044 20.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLX9 PF15341.1 EEA05865.1 - 0.00018 21.9 10.3 0.00018 21.9 7.1 2.2 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Glutaredoxin PF00462.19 EEA05866.1 - 6.8e-14 51.6 0.0 4e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EEA05866.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin YodA PF09223.6 EEA05866.1 - 0.068 12.8 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 YodA lipocalin-like domain GTP_EFTU PF00009.22 EEA05867.1 - 7.7e-48 162.4 0.1 1.3e-47 161.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEA05867.1 - 7.1e-16 57.8 0.0 2e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEA05867.1 - 2.1e-06 27.4 0.0 6.1e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEA05867.1 - 0.00026 20.9 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EEA05867.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EEA05867.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV Vps54 PF07928.7 EEA05868.1 - 2.2e-11 44.0 0.0 1e-10 41.8 0.0 2.2 1 0 0 1 1 1 1 Vps54-like protein Mem_trans PF03547.13 EEA05871.1 - 0.13 10.5 2.6 0.61 8.3 1.8 2.1 1 1 0 1 1 1 0 Membrane transport protein CAP18_C PF12153.3 EEA05872.1 - 0.003 17.1 0.3 0.0061 16.1 0.2 1.5 1 0 0 1 1 1 1 LPS binding domain of CAP18 (C terminal) RNA_pol_A_CTD PF03118.10 EEA05873.1 - 0.092 12.1 1.1 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain PH PF00169.24 EEA05873.1 - 0.15 12.2 3.8 0.068 13.3 0.6 1.9 2 0 0 2 2 2 0 PH domain Mito_carr PF00153.22 EEA05876.1 - 1.4e-41 140.0 0.8 2.2e-16 59.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ASFV_L11L PF05293.6 EEA05876.1 - 0.92 9.6 7.0 0.37 10.9 0.1 3.4 2 1 2 4 4 4 0 African swine fever virus (ASFV) L11L protein Evr1_Alr PF04777.8 EEA05877.1 - 2e-24 85.3 0.1 2.7e-24 84.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 EEA05877.1 - 0.015 15.4 0.3 0.046 13.8 0.1 1.8 1 1 1 2 2 2 0 Mediator complex subunit 27 SNF2_N PF00176.18 EEA05878.1 - 5.6e-75 251.9 0.2 5.6e-75 251.9 0.2 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EEA05878.1 - 3.4e-28 97.7 5.5 3.4e-28 97.7 3.8 3.0 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.26 EEA05878.1 - 6.4e-17 61.1 0.1 2.4e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RabGAP-TBC PF00566.13 EEA05879.1 - 4e-28 98.3 2.1 5.8e-28 97.8 1.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PX PF00787.19 EEA05880.1 - 1.4e-22 79.6 0.1 3.2e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 PX domain Peptidase_C1 PF00112.18 EEA05881.1 - 5.9e-31 108.0 11.3 1.9e-28 99.8 6.6 3.1 2 1 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.6 EEA05881.1 - 1.9e-07 31.2 0.1 0.00029 21.0 0.0 2.8 2 0 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EEA05881.1 - 0.078 11.4 0.4 0.13 10.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase C1-like family PEP-utilizers_C PF02896.13 EEA05881.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Gp-FAR-1 PF05823.7 EEA05882.1 - 0.0055 16.6 6.3 0.012 15.5 4.4 1.7 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NPV_P10 PF05531.7 EEA05882.1 - 0.023 14.9 0.9 0.035 14.3 0.1 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EEA05882.1 - 0.035 13.6 15.3 0.093 12.2 4.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EEA05882.1 - 0.069 13.2 8.1 0.083 13.0 5.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EEA05882.1 - 0.089 10.6 7.7 0.1 10.4 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCPsignal PF00015.16 EEA05882.1 - 0.096 12.2 0.8 0.17 11.3 0.5 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dad3 PF08656.5 EEA05882.1 - 0.12 12.0 5.5 0.11 12.1 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 RP-C_C PF11800.3 EEA05882.1 - 0.18 11.5 5.2 0.12 12.0 1.5 1.7 1 1 1 2 2 2 0 Replication protein C C-terminal region Tox-ODYAM1 PF15642.1 EEA05882.1 - 0.34 9.5 8.8 0.45 9.1 6.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus End3 PF12761.2 EEA05882.1 - 0.62 9.6 8.3 0.88 9.1 5.8 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HSP70 PF00012.15 EEA05882.1 - 0.63 7.8 8.8 0.75 7.6 6.1 1.2 1 0 0 1 1 1 0 Hsp70 protein G-7-MTase PF12803.2 EEA05882.1 - 0.64 9.1 7.7 1.3 8.1 5.1 1.5 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Allexi_40kDa PF05549.6 EEA05882.1 - 0.66 9.2 6.5 0.31 10.2 0.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2458 PF10454.4 EEA05882.1 - 0.74 9.6 9.1 0.074 12.9 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) PIGA PF08288.7 EEA05883.1 - 1.7e-40 137.2 1.5 3.8e-40 136.1 1.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EEA05883.1 - 9.9e-26 90.1 0.0 1.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEA05883.1 - 1.4e-19 70.4 0.4 3.9e-19 69.0 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEA05883.1 - 3.2e-10 40.2 0.0 5.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA05883.1 - 1e-08 35.5 0.0 1.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EEA05883.1 - 0.0003 20.6 0.4 0.00055 19.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EEA05883.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Spiralin PF05215.8 EEA05884.1 - 0.043 12.9 0.7 0.049 12.7 0.5 1.0 1 0 0 1 1 1 0 Spiralin DUF4458 PF14660.1 EEA05884.1 - 0.1 12.6 0.6 0.27 11.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) Ribos_L4_asso_C PF14374.1 EEA05884.1 - 0.15 11.9 5.9 0.29 11.0 4.1 1.4 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain DUF4207 PF13904.1 EEA05884.1 - 0.33 10.2 10.9 0.6 9.4 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) SET PF00856.23 EEA05885.1 - 3.4e-10 40.4 0.0 7.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 SET domain DNA_RNApol_7kD PF03604.8 EEA05885.1 - 0.0092 15.4 2.7 0.028 13.8 1.9 1.8 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.1 EEA05885.1 - 2 8.3 6.4 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 CpXC protein zf-DHHC PF01529.15 EEA05886.1 - 2e-26 92.4 16.0 2e-26 92.4 11.1 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pex24p PF06398.6 EEA05886.1 - 0.0037 16.0 1.5 0.0083 14.9 0.8 1.6 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Sulfate_transp PF00916.15 EEA05886.1 - 0.028 13.4 0.8 0.028 13.4 0.6 1.7 2 0 0 2 2 2 0 Sulfate transporter family Peptidase_M50 PF02163.17 EEA05886.1 - 0.045 12.6 0.3 0.13 11.1 0.2 1.8 1 1 0 1 1 1 0 Peptidase family M50 Cyclin_N PF00134.18 EEA05887.1 - 7.9e-12 44.8 1.7 7.9e-12 44.8 1.2 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA05887.1 - 9.4e-07 28.7 3.3 2.8e-06 27.2 1.3 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EEA05887.1 - 0.061 13.1 1.8 0.088 12.6 0.2 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin PF08613.6 EEA05887.1 - 4.8 7.5 12.7 0.29 11.5 4.1 2.4 2 1 0 2 2 2 0 Cyclin DUF288 PF03385.12 EEA05888.1 - 0.083 11.3 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF288 Glyco_transf_22 PF03901.12 EEA05889.1 - 1e-69 235.5 62.9 1.3e-69 235.2 43.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Kelch_4 PF13418.1 EEA05890.1 - 2.1e-44 149.0 7.9 1e-11 44.4 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EEA05890.1 - 4.6e-40 134.9 7.6 2.6e-09 37.0 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EEA05890.1 - 1.3e-39 133.5 2.6 8.8e-07 28.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EEA05890.1 - 5.6e-28 96.2 5.0 2.7e-08 33.2 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.10 EEA05890.1 - 8.7e-27 91.8 5.0 1.1e-07 31.3 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EEA05890.1 - 1.5e-25 88.2 15.8 2.3e-05 24.3 0.1 6.6 4 3 2 6 6 6 6 Kelch motif BTB PF00651.26 EEA05890.1 - 2.4e-21 75.8 3.8 3.9e-21 75.1 1.4 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EEA05890.1 - 0.0013 18.5 0.4 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch CorA PF01544.13 EEA05891.1 - 0.00062 18.8 9.1 0.0016 17.5 1.5 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein PS_Dcarbxylase PF02666.10 EEA05891.1 - 0.009 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Syntaxin-6_N PF09177.6 EEA05891.1 - 0.31 11.4 2.4 0.47 10.8 0.1 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal TGS PF02824.16 EEA05893.1 - 2.5e-21 75.2 0.1 4.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEA05893.1 - 1.4e-18 66.9 0.0 3.8e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA05893.1 - 9e-12 44.5 0.1 5.7e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEA05893.1 - 0.00028 20.7 0.0 0.89 9.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family ArgK PF03308.11 EEA05893.1 - 0.00035 19.4 0.2 0.0019 17.0 0.0 2.0 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 EEA05893.1 - 0.0093 15.4 0.1 8.5 5.7 0.0 3.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EEA05893.1 - 0.039 14.4 0.1 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein SRPRB PF09439.5 EEA05893.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EEA05893.1 - 0.087 12.7 0.2 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.15 EEA05894.1 - 6.7e-06 25.7 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Orthopox_B11R PF07033.6 EEA05894.1 - 0.029 13.8 0.3 0.068 12.6 0.2 1.7 1 1 0 1 1 1 0 Orthopoxvirus B11R protein Rad51 PF08423.6 EEA05895.1 - 7.3e-19 67.6 0.4 5e-18 64.9 0.3 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA05895.1 - 2.5e-11 43.3 0.0 3.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEA05895.1 - 6.2e-08 32.0 1.8 9.7e-08 31.4 0.8 1.7 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EEA05895.1 - 5.1e-06 26.6 0.0 1.8e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA05895.1 - 0.00028 21.6 0.2 0.00074 20.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA05895.1 - 0.00035 20.8 3.1 0.0018 18.5 2.2 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EEA05895.1 - 0.024 14.1 0.2 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EEA05895.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA05895.1 - 0.045 13.6 2.6 0.29 11.0 1.8 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEA05895.1 - 0.068 13.3 0.7 0.3 11.2 0.4 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEA05895.1 - 0.076 12.6 0.1 0.42 10.2 0.1 2.0 1 1 0 1 1 1 0 NACHT domain LAGLIDADG_1 PF00961.14 EEA05895.1 - 0.77 10.3 5.7 11 6.6 2.8 2.7 1 1 1 2 2 2 0 LAGLIDADG endonuclease DnaB_C PF03796.10 EEA05895.1 - 1 8.1 4.0 7.8 5.2 2.8 2.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain DUF92 PF01940.11 EEA05897.1 - 0.0035 16.5 0.5 0.0043 16.2 0.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF2079 PF09852.4 EEA05897.1 - 0.012 14.3 0.4 0.016 13.9 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF1212 PF06738.7 EEA05897.1 - 2.1 7.7 6.4 2.7 7.4 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) APG5 PF04106.7 EEA05898.1 - 2.9e-12 46.4 1.8 3.5e-12 46.2 1.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 PDEase_I PF00233.14 EEA05898.1 - 0.067 12.9 0.1 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Histone PF00125.19 EEA05899.1 - 2.7e-23 81.8 0.0 3.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA05899.1 - 0.0029 17.6 0.0 0.0086 16.1 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VID27 PF08553.5 EEA05900.1 - 1.9e-59 201.7 4.2 3.2e-59 200.9 2.9 1.3 1 0 0 1 1 1 1 VID27 cytoplasmic protein CDC73 PF05179.9 EEA05901.1 - 6.8e-37 127.3 0.1 1e-36 126.7 0.1 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family ATP-synt_C PF00137.16 EEA05902.1 - 1.7e-11 43.8 12.0 2.3e-11 43.4 8.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Claudin_2 PF13903.1 EEA05902.1 - 0.0062 16.2 0.6 0.0079 15.8 0.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nop52 PF05997.7 EEA05904.1 - 1.1e-41 142.6 11.4 1.1e-41 142.6 6.4 1.9 2 0 0 2 2 2 1 Nucleolar protein,Nop52 RabGAP-TBC PF00566.13 EEA05905.1 - 7.3e-58 195.5 1.2 1.3e-57 194.6 0.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TMEM154 PF15102.1 EEA05906.1 - 5.4e-05 22.9 0.0 9.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EEA05906.1 - 8.7e-05 22.3 0.0 0.00011 22.0 0.0 1.0 1 0 0 1 1 1 1 Rifin/stevor family Baculo_E56 PF04639.7 EEA05906.1 - 0.00032 19.4 1.5 0.00036 19.3 0.1 1.7 2 0 0 2 2 2 1 Baculoviral E56 protein, specific to ODV envelope ODV-E18 PF10717.4 EEA05906.1 - 0.00089 18.6 0.5 0.0017 17.7 0.3 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 EEA05906.1 - 0.0035 17.7 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EEA05906.1 - 0.004 17.1 0.1 0.006 16.6 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 EEA05906.1 - 0.0078 15.9 0.2 0.024 14.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF1183 PF06682.7 EEA05906.1 - 0.0083 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Herpes_gE PF02480.11 EEA05906.1 - 0.02 13.1 0.0 0.025 12.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.4 EEA05906.1 - 0.024 13.2 0.0 0.024 13.2 0.0 1.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Plasmodium_Vir PF05795.6 EEA05906.1 - 0.024 13.8 0.1 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CD34_antigen PF06365.7 EEA05906.1 - 0.027 14.1 0.1 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family ATG22 PF11700.3 EEA05906.1 - 0.028 12.9 0.1 0.028 12.9 0.1 1.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Spore_YpjB PF09577.5 EEA05906.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF1970 PF09301.5 EEA05906.1 - 0.053 13.5 0.9 0.053 13.5 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) BatD PF13584.1 EEA05906.1 - 0.064 11.8 0.1 0.085 11.4 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Protocadherin PF08374.6 EEA05906.1 - 0.069 12.7 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Chordopox_A13L PF05961.6 EEA05906.1 - 0.077 12.9 0.2 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3827 PF12877.2 EEA05906.1 - 0.088 10.8 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1191 PF06697.7 EEA05906.1 - 0.093 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MASE1 PF05231.9 EEA05906.1 - 0.13 11.2 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 MASE1 DUF4381 PF14316.1 EEA05906.1 - 0.29 11.2 1.3 0.5 10.4 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Cation_ATPase_C PF00689.16 EEA05906.1 - 0.44 10.0 2.6 0.91 9.0 1.8 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Cir_Bir_Yir PF06022.6 EEA05906.1 - 3.4 6.8 10.0 2.4 7.3 0.5 2.3 1 1 1 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir XhlA PF10779.4 EEA05906.1 - 4.7 7.2 7.5 1.8 8.5 2.9 1.9 2 0 0 2 2 2 0 Haemolysin XhlA ThiF PF00899.16 EEA05907.1 - 1.5e-31 109.0 0.4 2.7e-31 108.2 0.3 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EEA05907.1 - 0.0076 16.4 0.1 0.032 14.4 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding MoeZ_MoeB PF05237.8 EEA05907.1 - 0.012 15.1 0.6 0.05 13.1 0.4 2.1 1 0 0 1 1 1 0 MoeZ/MoeB domain Shikimate_DH PF01488.15 EEA05907.1 - 0.046 13.8 0.2 0.096 12.7 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arm PF00514.18 EEA05907.1 - 0.089 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat RNase_PH PF01138.16 EEA05908.1 - 1.3e-16 61.1 0.1 4.8e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 NDK PF00334.14 EEA05909.1 - 1.7e-52 176.8 0.0 1.9e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ORC2 PF04084.9 EEA05910.1 - 1.4e-45 155.5 8.8 1.7e-45 155.2 6.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Pkinase PF00069.20 EEA05911.1 - 9.5e-65 218.3 0.0 2e-64 217.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA05911.1 - 2e-33 115.5 0.0 3.2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA05911.1 - 0.00077 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA05911.1 - 0.03 13.3 0.1 0.068 12.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA05911.1 - 0.24 11.1 0.0 10 5.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spc97_Spc98 PF04130.8 EEA05912.1 - 9.5e-63 212.3 22.5 9.5e-63 212.3 15.6 2.2 1 1 1 2 2 2 2 Spc97 / Spc98 family Hexapep PF00132.19 EEA05913.1 - 2.7e-18 64.5 17.9 2.9e-06 26.5 1.1 4.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EEA05913.1 - 0.35 9.3 9.3 1.2 7.5 0.4 3.1 1 1 2 3 3 3 0 L-fucokinase RRM_1 PF00076.17 EEA05914.1 - 7.4e-19 67.1 0.7 1.7e-09 37.1 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05914.1 - 5.9e-16 58.2 0.3 1.8e-08 34.2 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05914.1 - 1.2e-06 28.3 0.0 1.7e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA05914.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EEA05914.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif QRPTase_C PF01729.14 EEA05914.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CRIC_ras_sig PF10534.4 EEA05915.1 - 0.067 13.2 1.0 2.4 8.2 0.0 2.7 2 1 1 3 3 3 0 Connector enhancer of kinase suppressor of ras CRT-like PF08627.5 EEA05915.1 - 0.51 10.2 3.6 0.23 11.3 0.6 1.8 2 0 0 2 2 2 0 CRT-like Ebp2 PF05890.7 EEA05916.1 - 2.1e-36 125.6 17.9 2.3e-36 125.4 12.4 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 ChiC PF06483.6 EEA05918.1 - 0.0039 16.9 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Chitinase C Crisp PF08562.5 EEA05918.1 - 0.055 13.7 0.9 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 Crisp DUF1573 PF07610.6 EEA05918.1 - 0.39 10.3 9.0 0.34 10.5 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1573) RRM_1 PF00076.17 EEA05920.1 - 7.5e-16 57.5 0.0 1.9e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA05920.1 - 9.8e-10 38.2 0.0 2.3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA05920.1 - 0.00045 20.0 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4253 PF14062.1 EEA05920.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Stk19 PF10494.4 EEA05921.1 - 6e-20 71.7 0.0 1.1e-19 70.7 0.0 1.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1493 PF07377.7 EEA05921.1 - 0.081 13.0 0.2 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) ENTH PF01417.15 EEA05921.1 - 0.77 9.6 2.9 3 7.7 1.5 2.2 1 1 1 2 2 2 0 ENTH domain Rb_C PF08934.5 EEA05924.1 - 0.0088 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Rb C-terminal domain RNase_PH PF01138.16 EEA05925.1 - 7.4e-29 100.7 0.1 1.3e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M22 PF00814.20 EEA05926.1 - 5e-78 262.2 0.0 6.3e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family HVSL PF09749.4 EEA05927.1 - 0.017 14.1 0.1 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein Myotub-related PF06602.9 EEA05928.1 - 1.1e-102 343.4 2.3 2.2e-102 342.4 1.6 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EEA05928.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EEA05928.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEA05928.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1546 PF07571.8 EEA05928.1 - 0.36 10.9 1.6 6.3 6.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) DER1 PF04511.10 EEA05929.1 - 1.4e-34 119.3 7.6 2e-34 118.8 5.3 1.2 1 0 0 1 1 1 1 Der1-like family PCI PF01399.22 EEA05930.1 - 1e-16 61.1 3.8 5.5e-16 58.7 2.6 2.3 1 0 0 1 1 1 1 PCI domain DUF2042 PF09743.4 EEA05930.1 - 0.00011 21.5 1.0 0.00027 20.3 0.7 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) PCI_Csn8 PF10075.4 EEA05930.1 - 0.00091 19.0 1.3 0.0022 17.7 0.7 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_21 PF09976.4 EEA05930.1 - 0.0049 16.8 2.5 0.9 9.4 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat NAD_binding_6 PF08030.7 EEA05930.1 - 0.046 13.6 0.3 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aminotran_1_2 PF00155.16 EEA05932.1 - 4.2e-42 144.3 0.0 6.1e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA05932.1 - 1.5e-05 23.4 0.0 2.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EEA05932.1 - 0.0043 16.2 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEA05932.1 - 0.038 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEA05932.1 - 0.07 12.1 0.2 0.43 9.5 0.1 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Endonuclease_NS PF01223.18 EEA05932.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease WD40 PF00400.27 EEA05933.1 - 1.7e-40 135.4 27.5 7.3e-10 38.3 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 EEA05933.1 - 0.00079 19.1 0.3 19 4.9 0.0 4.2 2 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EEA05933.1 - 0.0063 15.9 0.2 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EEA05933.1 - 0.016 15.4 2.4 0.11 12.8 0.6 3.1 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.16 EEA05933.1 - 0.14 11.7 0.5 8.9 6.0 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat SF-assemblin PF06705.6 EEA05934.1 - 4.6e-39 134.0 33.1 6.2e-39 133.6 23.0 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF3832 PF12909.2 EEA05934.1 - 0.0035 17.3 2.8 0.32 11.0 0.5 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3832) RRXRR PF14239.1 EEA05934.1 - 0.0063 15.9 0.2 0.015 14.6 0.2 1.7 1 0 0 1 1 1 1 RRXRR protein E6 PF00518.12 EEA05934.1 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Early Protein (E6) ApoO PF09769.4 EEA05934.1 - 3.2 7.4 9.3 2.3 7.9 0.9 2.6 2 1 0 2 2 2 0 Apolipoprotein O Vps39_2 PF10367.4 EEA05935.1 - 0.037 14.2 0.7 1.3 9.2 0.2 2.6 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Ank_3 PF13606.1 EEA05936.1 - 1.5e-05 24.7 0.0 0.047 13.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EEA05936.1 - 1.8e-05 24.2 0.0 0.033 13.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEA05936.1 - 2.1e-05 24.7 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA05936.1 - 8.4e-05 22.6 0.0 0.014 15.6 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA05936.1 - 0.0045 17.4 0.1 0.025 15.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Thioredoxin PF00085.15 EEA05937.1 - 1.6e-41 140.1 0.0 2e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EEA05937.1 - 7.9e-12 45.3 0.6 0.0014 18.7 0.1 4.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEA05937.1 - 1.2e-09 38.0 0.3 0.00036 20.4 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EEA05937.1 - 1.7e-09 37.6 0.2 0.031 14.3 0.1 5.1 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EEA05937.1 - 8.8e-05 22.0 0.6 0.21 11.1 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.16 EEA05937.1 - 0.0047 16.5 0.0 1.5 8.4 0.0 2.8 2 0 0 2 2 2 1 AhpC/TSA family HyaE PF07449.6 EEA05937.1 - 0.018 14.9 0.0 0.071 13.0 0.0 2.0 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 EEA05937.1 - 0.021 14.3 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Redoxin DUF520 PF04461.8 EEA05937.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Glutaredoxin PF00462.19 EEA05937.1 - 0.055 13.4 0.1 17 5.5 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin Ank_2 PF12796.2 EEA05938.1 - 3.9e-21 75.1 0.6 3.5e-07 30.4 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA05938.1 - 1.5e-17 62.4 4.6 8.7e-05 22.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EEA05938.1 - 9.3e-14 51.5 1.2 3.9e-06 27.2 0.1 5.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA05938.1 - 6.1e-09 35.8 1.0 0.0006 19.9 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA05938.1 - 4.3e-08 32.6 10.0 0.016 15.4 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat F-box PF00646.28 EEA05939.1 - 0.084 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain WGG PF10273.4 EEA05940.1 - 9.5e-19 67.2 0.1 1.5e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3244 PF11589.3 EEA05941.1 - 0.068 12.8 1.6 0.17 11.6 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3244) Reo_sigmaC PF04582.7 EEA05942.1 - 0.0097 15.1 1.5 0.0097 15.1 1.0 2.8 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EEA05942.1 - 0.042 13.8 1.0 0.042 13.8 0.7 5.9 2 2 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DASH_Dam1 PF08653.5 EEA05942.1 - 0.14 11.9 3.4 3.1 7.6 0.1 4.0 3 1 0 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.7 EEA05942.1 - 1.6 9.0 21.9 0.35 11.1 0.1 5.8 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2935 PF11155.3 EEA05942.1 - 3.5 7.7 19.0 1.1 9.3 0.6 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF2935) PUB PF09409.5 EEA05943.1 - 7.8e-12 44.8 0.0 2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 PUB domain TPR_7 PF13176.1 EEA05943.1 - 0.012 15.4 0.0 0.088 12.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat UBX PF00789.15 EEA05943.1 - 0.076 13.0 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 UBX domain TPR_19 PF14559.1 EEA05943.1 - 0.1 12.9 0.0 0.71 10.2 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S30 PF04758.9 EEA05944.1 - 1.8e-26 91.6 11.7 2e-26 91.5 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 P5CR_dimer PF14748.1 EEA05945.1 - 2.9e-22 78.6 0.0 4.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEA05945.1 - 1.2e-16 60.9 0.1 2.6e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EEA05945.1 - 0.001 18.8 0.7 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EEA05945.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA05945.1 - 0.011 14.8 0.0 0.027 13.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.12 EEA05945.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase GFO_IDH_MocA PF01408.17 EEA05945.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TRAPP PF04051.11 EEA05948.1 - 1.6e-36 125.1 0.0 1.9e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Alpha-amylase PF00128.19 EEA05949.1 - 2.6e-26 92.7 0.0 3e-12 46.5 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EEA05949.1 - 0.00011 22.1 0.1 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GYF PF02213.11 EEA05950.1 - 1.3e-10 40.7 0.9 3.9e-10 39.1 0.6 1.9 1 0 0 1 1 1 1 GYF domain Gp_dh_C PF02800.15 EEA05953.1 - 7e-67 223.7 0.0 9.2e-67 223.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEA05953.1 - 2e-62 209.6 0.0 3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA05953.1 - 0.023 13.8 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hexokinase_2 PF03727.11 EEA05954.1 - 1.1e-49 168.8 0.1 1.5e-49 168.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEA05954.1 - 5.7e-41 140.1 0.0 2e-22 79.5 0.0 2.3 1 1 1 2 2 2 2 Hexokinase DUF1972 PF09314.6 EEA05954.1 - 0.028 13.9 0.7 0.38 10.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1972) NUDIX_2 PF13869.1 EEA05955.1 - 2e-60 203.3 0.0 2.4e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Asp PF00026.18 EEA05956.1 - 2.7e-76 256.8 0.0 3.8e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA05956.1 - 2e-10 40.8 0.0 2.6e-08 33.9 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA05956.1 - 0.00031 21.1 0.0 1.6 9.3 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease Pacs-1 PF10254.4 EEA05956.1 - 0.015 13.9 0.0 0.034 12.7 0.0 1.5 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein gag-asp_proteas PF13975.1 EEA05956.1 - 0.098 12.4 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ras PF00071.17 EEA05957.1 - 8.6e-60 200.8 0.3 1e-59 200.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA05957.1 - 4.1e-18 66.0 0.2 7.9e-18 65.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA05957.1 - 3e-13 49.3 0.2 3.7e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA05957.1 - 1.4e-06 27.6 0.1 1.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA05957.1 - 1.8e-05 24.2 0.2 3.8e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA05957.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA05957.1 - 0.0016 18.5 0.0 0.01 15.9 0.0 2.0 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA05957.1 - 0.014 14.5 0.1 0.036 13.2 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EEA05957.1 - 0.015 14.4 0.1 0.02 14.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EEA05957.1 - 0.046 13.7 0.1 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EEA05957.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SET PF00856.23 EEA05958.1 - 0.019 15.2 0.1 0.038 14.3 0.1 1.8 1 1 0 1 1 1 0 SET domain Rubis-subs-bind PF09273.6 EEA05958.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Ribosomal_L7Ae PF01248.21 EEA05959.1 - 3.5e-24 84.1 0.3 4.1e-24 83.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fib_alpha PF08702.5 EEA05960.1 - 0.081 13.0 1.6 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EEA05960.1 - 0.19 12.0 1.7 0.63 10.3 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CDT1 PF08839.6 EEA05961.1 - 3.2e-24 85.6 0.3 9.2e-24 84.2 0.2 1.8 1 0 0 1 1 1 1 DNA replication factor CDT1 like RNase_HII PF01351.13 EEA05962.1 - 7.2e-52 175.9 0.0 2.8e-51 174.0 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease HII Topo_Zn_Ribbon PF08272.6 EEA05962.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Dpy19 PF10034.4 EEA05964.1 - 2.7e-144 481.8 30.1 3.5e-144 481.4 20.9 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation TPR_17 PF13431.1 EEA05964.1 - 0.003 17.6 0.9 0.03 14.5 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA05964.1 - 0.04 13.5 0.3 0.095 12.3 0.2 1.6 1 0 0 1 1 1 0 TPR repeat TRAM_LAG1_CLN8 PF03798.11 EEA05965.1 - 2.2e-28 99.1 31.3 4e-28 98.3 21.7 1.4 1 0 0 1 1 1 1 TLC domain TAXi_N PF14543.1 EEA05966.1 - 2.8e-17 63.1 1.3 2.8e-17 63.1 0.9 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.18 EEA05966.1 - 3.5e-14 52.7 0.5 3.7e-13 49.4 0.3 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA05966.1 - 0.00011 21.7 0.0 0.00044 19.8 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EEA05966.1 - 0.081 12.7 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SMC_N PF02463.14 EEA05967.1 - 2.9e-65 219.5 14.3 4.4e-37 127.4 1.9 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA05967.1 - 1.9e-21 76.2 0.0 6.1e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EEA05967.1 - 9.3e-08 32.6 34.1 9.3e-08 32.6 23.6 6.6 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EEA05967.1 - 2.6e-07 30.9 53.9 2.3e-06 27.8 2.8 5.4 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEA05967.1 - 0.00029 20.2 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA05967.1 - 0.0084 16.4 22.4 0.022 15.0 0.0 5.4 4 1 0 4 4 4 2 ABC transporter Reo_sigmaC PF04582.7 EEA05967.1 - 8.4 5.4 29.8 7.8 5.5 1.2 4.9 2 2 5 7 7 7 0 Reovirus sigma C capsid protein Adaptin_N PF01602.15 EEA05968.1 - 6.9e-70 235.8 17.5 1.2e-69 235.0 12.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.1 EEA05968.1 - 0.00095 19.3 0.2 0.0032 17.6 0.0 2.1 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 EEA05968.1 - 0.082 13.1 0.6 2.7 8.3 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.17 EEA05968.1 - 0.12 12.5 0.8 36 4.8 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat dsDNA_bind PF01984.15 EEA05969.1 - 2.2e-17 62.9 3.3 2.6e-17 62.7 2.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain T3SS_LEE_assoc PF13327.1 EEA05969.1 - 0.0044 16.5 0.1 0.0059 16.1 0.1 1.1 1 0 0 1 1 1 1 Type III secretion system subunit DUF4332 PF14229.1 EEA05969.1 - 0.006 16.5 0.3 0.0069 16.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DUF1115 PF06544.7 EEA05969.1 - 0.041 13.5 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF1103 PF06513.6 EEA05969.1 - 0.087 12.2 0.2 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DFP PF04127.10 EEA05972.1 - 2.3e-15 56.6 0.0 1.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein F-box-like PF12937.2 EEA05973.1 - 0.0044 16.7 1.6 0.011 15.4 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA05973.1 - 0.064 12.9 1.7 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 F-box domain Ribosomal_L10 PF00466.15 EEA05974.1 - 3.1e-21 75.1 0.1 6.1e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EEA05974.1 - 1.4e-06 28.6 2.3 6e-06 26.5 1.6 2.2 1 1 0 1 1 1 1 60s Acidic ribosomal protein adh_short PF00106.20 EEA05975.1 - 2.2e-18 66.7 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA05975.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain zf-met PF12874.2 EEA05975.1 - 0.0043 17.2 0.2 2.1 8.6 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Epimerase PF01370.16 EEA05975.1 - 0.0085 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEA05975.1 - 0.13 12.3 0.1 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1647 PF07801.6 EEA05976.1 - 0.0042 16.6 0.6 0.0088 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) AD PF09793.4 EEA05977.1 - 7.8e-21 73.7 0.0 1.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.7 EEA05977.1 - 0.00072 18.9 0.1 0.025 13.9 0.0 2.1 2 0 0 2 2 2 2 Gemin6 protein ThiF PF00899.16 EEA05978.1 - 4.6e-46 156.0 4.6 6.4e-34 116.6 0.0 3.2 4 0 0 4 4 4 2 ThiF family UBA_e1_C PF09358.5 EEA05978.1 - 1.4e-32 112.4 0.3 3.5e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EEA05978.1 - 1.5e-29 101.3 3.5 1.1e-22 79.3 0.2 3.2 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEA05978.1 - 1.7e-18 65.7 0.4 4.1e-18 64.4 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site TEP1_N PF05386.6 EEA05978.1 - 0.83 9.1 3.7 8.3 5.9 0.6 2.6 2 0 0 2 2 2 0 TEP1 N-terminal domain WD40 PF00400.27 EEA05979.1 - 8.9e-35 117.3 26.8 1e-09 37.8 0.2 7.4 6 1 0 6 6 6 5 WD domain, G-beta repeat PFU PF09070.6 EEA05979.1 - 3.6e-29 101.1 0.4 6.8e-29 100.2 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EEA05979.1 - 4.7e-15 55.0 2.4 8.1e-15 54.3 1.7 1.3 1 0 0 1 1 1 1 PUL domain Nup160 PF11715.3 EEA05979.1 - 3e-07 28.9 4.4 0.00036 18.7 0.2 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF2975 PF11188.3 EEA05980.1 - 3.4 7.4 15.0 1.1 8.9 8.2 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF2417 PF10329.4 EEA05980.1 - 8 5.7 13.8 5.5 6.3 4.9 2.3 1 1 1 2 2 2 0 Region of unknown function (DUF2417) ATP-synt PF00231.14 EEA05982.1 - 6.8e-65 219.2 0.3 7.7e-65 219.0 0.2 1.0 1 0 0 1 1 1 1 ATP synthase ubiquitin PF00240.18 EEA05983.1 - 3.6e-18 64.7 0.1 5.6e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEA05983.1 - 4.1e-08 32.8 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EEA05983.1 - 3.7e-07 29.7 0.0 6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EEA05983.1 - 0.00033 20.0 0.2 0.0044 16.4 0.0 2.9 3 0 0 3 3 3 1 CUE domain DUF2407 PF10302.4 EEA05983.1 - 0.0036 17.4 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEA05983.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like tRNA-synt_2 PF00152.15 EEA05984.1 - 4.3e-86 288.7 0.0 5.4e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA05984.1 - 6.9e-11 41.8 0.1 1.6e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEA05984.1 - 1.2e-07 31.1 0.0 0.0017 17.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EEA05984.1 - 0.039 13.5 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 EEA05984.1 - 0.041 13.3 0.1 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like HEAT PF02985.17 EEA05985.1 - 6.2e-09 35.1 6.5 14 6.1 0.0 8.3 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 EEA05985.1 - 9.4e-08 32.2 0.0 0.03 14.5 0.0 5.3 4 1 0 4 4 4 2 HEAT repeats Mon1 PF03164.9 EEA05986.1 - 3.1e-35 121.5 9.8 9.6e-33 113.3 6.8 2.3 1 1 0 1 1 1 1 Trafficking protein Mon1 DUF1044 PF06296.7 EEA05986.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1044) RWD PF05773.17 EEA05986.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 RWD domain Vps35 PF03635.12 EEA05987.1 - 2.5e-249 829.4 14.3 3.1e-249 829.1 9.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribosomal_L31e PF01198.14 EEA05988.1 - 4.7e-34 115.9 0.5 5.6e-34 115.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ank_2 PF12796.2 EEA05990.1 - 5.1e-29 100.4 0.0 1.9e-09 37.7 0.0 4.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA05990.1 - 9.1e-28 94.6 3.9 3.3e-05 23.4 0.0 5.9 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EEA05990.1 - 6.4e-24 81.6 1.7 6e-05 22.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEA05990.1 - 2.3e-21 75.3 0.0 5.6e-05 23.2 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA05990.1 - 3.5e-21 75.1 0.7 2.9e-06 27.6 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Sushi PF00084.15 EEA05990.1 - 4.7e-07 30.0 0.4 1e-06 28.9 0.3 1.6 1 0 0 1 1 1 1 Sushi domain (SCR repeat) TfoX_N PF04993.8 EEA05991.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 TfoX N-terminal domain TBCC PF07986.7 EEA05994.1 - 2e-25 88.5 0.9 4.3e-25 87.4 0.6 1.5 2 0 0 2 2 2 1 Tubulin binding cofactor C DUF2650 PF10853.3 EEA05994.1 - 0.049 13.0 1.7 0.094 12.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) YTV PF07639.6 EEA05997.1 - 1.8 8.3 6.1 0.17 11.6 0.6 1.9 2 0 0 2 2 2 0 YTV ERGIC_N PF13850.1 EEA05998.1 - 2.7 8.0 7.4 4.7 7.2 0.3 2.8 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.24 EEA06003.1 - 9.8e-45 151.9 0.0 2.8e-44 150.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA06003.1 - 4.3e-09 36.2 0.2 1.6e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA06003.1 - 9.3e-09 35.4 0.0 2.6e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEA06003.1 - 1.6e-06 28.2 0.7 0.00021 21.4 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA06003.1 - 1.8e-05 24.8 0.5 7.2e-05 22.8 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 EEA06003.1 - 2.5e-05 23.3 0.0 5.9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEA06003.1 - 9.6e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA06003.1 - 0.0001 21.4 0.0 0.00026 20.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEA06003.1 - 0.00014 22.6 0.0 0.00059 20.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EEA06003.1 - 0.00043 19.7 0.2 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EEA06003.1 - 0.00048 19.8 0.1 0.018 14.7 0.0 2.7 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.17 EEA06003.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EEA06003.1 - 0.00085 19.2 0.1 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA06003.1 - 0.00088 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA06003.1 - 0.00091 18.6 1.6 0.026 13.9 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EEA06003.1 - 0.001 18.6 0.1 0.029 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA06003.1 - 0.0011 19.3 0.1 0.0083 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA06003.1 - 0.0011 18.6 0.3 0.0026 17.4 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EEA06003.1 - 0.0013 17.9 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EEA06003.1 - 0.0014 19.0 0.3 1.9 8.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EEA06003.1 - 0.0026 17.3 0.2 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEA06003.1 - 0.0034 16.1 0.0 0.011 14.4 0.0 1.7 2 1 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 EEA06003.1 - 0.0035 16.9 0.2 0.0074 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EEA06003.1 - 0.0045 16.4 0.1 0.094 12.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EEA06003.1 - 0.0058 16.2 0.3 0.079 12.6 0.1 2.3 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EEA06003.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin GrpE PF01025.14 EEA06003.1 - 0.0066 15.9 0.9 0.1 12.1 0.1 2.3 2 0 0 2 2 2 1 GrpE UPF0079 PF02367.12 EEA06003.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EEA06003.1 - 0.014 15.0 0.8 0.23 11.1 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EEA06003.1 - 0.017 15.1 0.3 0.12 12.4 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEA06003.1 - 0.019 13.8 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEA06003.1 - 0.02 13.7 0.0 0.046 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3363 PF11843.3 EEA06003.1 - 0.039 12.6 0.0 0.065 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_30 PF13604.1 EEA06003.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 EEA06003.1 - 0.048 13.5 5.1 0.084 12.7 3.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KaiC PF06745.8 EEA06003.1 - 0.061 12.4 3.1 0.75 8.8 0.0 2.9 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 EEA06003.1 - 0.066 12.4 0.1 0.18 11.0 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF3450 PF11932.3 EEA06003.1 - 0.069 12.4 1.0 0.14 11.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KAP_NTPase PF07693.9 EEA06003.1 - 0.11 11.4 0.1 23 3.8 0.1 3.0 3 0 0 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.22 EEA06003.1 - 0.18 12.0 1.5 0.52 10.6 0.0 2.6 2 2 0 2 2 2 0 ABC transporter polyprenyl_synt PF00348.12 EEA06004.1 - 1.6e-36 125.5 0.0 2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UQ_con PF00179.21 EEA06006.1 - 3.7e-20 71.7 0.1 5e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA06006.1 - 0.0054 16.6 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain YrhC PF14143.1 EEA06007.1 - 0.65 9.9 3.3 0.47 10.4 0.1 2.2 2 1 0 2 2 2 0 YrhC-like protein DUF2518 PF10726.4 EEA06007.1 - 9.1 5.8 9.1 1.7 8.1 3.6 1.8 1 1 1 2 2 2 0 Protein of function (DUF2518) PI-PLC-X PF00388.14 EEA06008.1 - 5.7e-58 194.4 0.0 1e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEA06008.1 - 2.5e-31 108.1 0.0 5.7e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EEA06008.1 - 4.3e-12 45.8 0.5 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EEA06008.1 - 3.2e-10 39.6 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EEA06008.1 - 9.7e-10 37.0 0.1 0.0023 17.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EEA06008.1 - 4.7e-09 36.2 3.9 7.7e-07 29.1 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair Mcp5_PH PF12814.2 EEA06008.1 - 1.3e-06 28.3 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_8 PF13833.1 EEA06008.1 - 2.3e-06 27.0 0.2 0.00031 20.2 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA06008.1 - 6.1e-06 25.6 5.3 0.14 12.0 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_10 PF14788.1 EEA06008.1 - 0.00021 20.8 0.1 0.00052 19.6 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.2 EEA06008.1 - 0.0012 18.5 0.2 0.017 14.8 0.0 2.8 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand GDPD PF03009.12 EEA06008.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.27 EEA06009.1 - 1e-08 34.6 4.1 0.0013 18.5 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EEA06009.1 - 0.002 18.3 0.3 2.1 8.7 0.0 3.7 4 0 0 4 4 4 2 PQQ-like domain Oxysterol_BP PF01237.13 EEA06010.1 - 4.4e-121 403.6 0.2 7.6e-121 402.8 0.1 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 EEA06010.1 - 1.1e-06 28.7 1.0 3e-06 27.3 0.7 1.8 1 0 0 1 1 1 1 PH domain GDPD PF03009.12 EEA06011.1 - 3e-38 131.7 0.0 5.5e-38 130.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Epimerase PF01370.16 EEA06012.1 - 1.6e-47 161.9 0.0 1.9e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEA06012.1 - 2e-22 78.9 0.0 3.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EEA06012.1 - 7e-14 51.4 0.0 2.8e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EEA06012.1 - 4.3e-13 48.6 0.0 1.6e-12 46.7 0.0 1.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEA06012.1 - 3.5e-11 42.5 0.0 1.1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EEA06012.1 - 2.6e-08 33.1 0.0 4e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EEA06012.1 - 1.6e-07 31.3 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA06012.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EEA06012.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EEA06012.1 - 0.021 15.1 0.0 0.47 10.8 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain DUF3240 PF11582.3 EEA06014.1 - 0.057 13.3 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) Nop53 PF07767.6 EEA06015.1 - 2.3e-06 26.8 10.8 2.3e-06 26.8 7.5 2.3 2 1 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) PDCD2_C PF04194.8 EEA06017.1 - 1.8e-31 108.9 0.8 3.3e-31 108.1 0.2 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PI3_PI4_kinase PF00454.22 EEA06018.1 - 3.5e-41 141.1 2.5 1.5e-40 139.1 0.1 3.3 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EEA06018.1 - 2.8e-11 42.6 0.8 1.3e-10 40.5 0.0 2.6 2 0 0 2 2 2 1 FATC domain Bax1-I PF01027.15 EEA06019.1 - 2.9e-31 108.6 39.5 3.4e-31 108.4 27.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Sec7 PF01369.15 EEA06020.1 - 1.5e-59 200.9 2.5 1.5e-59 200.9 1.8 2.5 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EEA06020.1 - 2.4e-21 75.8 6.4 2.7e-20 72.4 4.4 3.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Flavodoxin_1 PF00258.20 EEA06021.1 - 3.7e-19 69.1 0.0 6.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EEA06021.1 - 7e-19 68.1 0.1 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEA06021.1 - 7.5e-11 42.5 0.0 2.6e-10 40.8 0.0 2.0 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain LSM PF01423.17 EEA06022.1 - 4.1e-17 61.4 0.4 6.1e-17 60.9 0.3 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA06022.1 - 0.072 13.0 0.0 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain E1-E2_ATPase PF00122.15 EEA06023.1 - 9.6e-64 214.5 1.5 9.6e-64 214.5 1.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA06023.1 - 1.8e-35 122.0 2.1 1.8e-35 122.0 1.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA06023.1 - 2.2e-30 106.6 0.1 2.3e-24 86.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA06023.1 - 5.8e-18 64.1 0.4 1.5e-17 62.7 0.2 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEA06023.1 - 6.9e-14 52.4 1.6 7.7e-13 49.0 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA06023.1 - 3.6e-10 39.6 0.3 6.9e-06 25.9 0.0 3.4 3 1 0 3 3 3 2 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA06023.1 - 0.0014 18.2 0.6 0.0014 18.2 0.4 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEA06023.1 - 0.2 11.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3671 PF12420.3 EEA06023.1 - 6 6.8 8.8 3.1 7.8 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function Peptidase_M20 PF01546.23 EEA06024.1 - 2.6e-24 85.7 0.0 3.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA06024.1 - 4e-11 42.6 0.0 9.3e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEA06024.1 - 0.094 12.4 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Brix PF04427.13 EEA06026.1 - 2.8e-49 167.3 1.0 3.8e-49 166.9 0.7 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 EEA06027.1 - 1.6e-16 59.4 9.3 7.9e-08 31.8 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA06027.1 - 0.011 14.4 0.7 5.5 5.6 0.0 3.5 1 1 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 EEA06027.1 - 0.029 12.5 0.0 3.3 5.7 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Mg_trans_NIPA PF05653.9 EEA06028.1 - 2.2e-26 92.5 20.2 1.3e-15 57.2 3.4 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EEA06028.1 - 5.6e-06 26.5 10.1 5.6e-06 26.5 7.0 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA06028.1 - 6.3e-06 26.2 4.5 6.3e-06 26.2 3.1 3.2 4 0 0 4 4 4 2 EamA-like transporter family MOZART1 PF12554.3 EEA06029.1 - 5e-18 64.3 1.4 5.8e-18 64.0 1.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Aa_trans PF01490.13 EEA06030.1 - 7.1e-29 100.5 28.2 2e-28 99.0 19.5 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4227 PF14004.1 EEA06030.1 - 0.84 9.5 4.1 8.6 6.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) CTDII PF01556.13 EEA06031.1 - 2.3e-27 94.7 0.4 3.8e-22 77.9 0.1 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EEA06031.1 - 1.3e-26 92.1 0.5 2.2e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEA06031.1 - 0.059 13.4 2.6 0.12 12.4 1.8 1.4 1 0 0 1 1 1 0 DnaJ central domain CDP-OH_P_transf PF01066.16 EEA06032.1 - 2.4e-14 53.4 19.9 2.5e-13 50.1 13.0 3.1 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase DnaJ PF00226.26 EEA06033.1 - 1.2e-19 69.7 0.7 2.2e-19 68.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Sigma70_ner PF04546.8 EEA06033.1 - 0.02 14.4 2.2 11 5.6 0.0 3.0 2 1 1 3 3 3 0 Sigma-70, non-essential region Peptidase_C71 PF12386.3 EEA06033.1 - 0.03 13.7 0.9 0.056 12.8 0.6 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei COX6C PF02937.10 EEA06033.1 - 0.063 13.1 2.0 0.15 11.9 1.4 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc zf-LITAF-like PF10601.4 EEA06034.1 - 1.3e-18 66.6 5.0 1.3e-18 66.6 3.5 2.3 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zf-Di19 PF05605.7 EEA06034.1 - 0.77 9.9 4.2 0.77 9.9 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 EEA06034.1 - 6.8 6.4 7.9 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF383 PF04063.9 EEA06036.1 - 0.00037 20.0 1.0 0.00058 19.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) F-protein PF00469.15 EEA06036.1 - 0.15 11.3 1.1 0.21 10.9 0.8 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Tom22 PF04281.8 EEA06037.1 - 1e-05 25.0 0.0 1.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 EMG1 PF03587.9 EEA06038.1 - 4.5e-42 143.6 0.1 5.4e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase EMG1 PF03587.9 EEA06039.1 - 5.2e-54 182.6 0.3 7e-54 182.1 0.2 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DnaJ PF00226.26 EEA06040.1 - 0.0023 17.6 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain bPH_3 PF14470.1 EEA06042.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain Tubulin PF00091.20 EEA06043.1 - 9.5e-71 238.0 0.0 1.3e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA06043.1 - 6.9e-51 171.5 0.2 2e-50 170.0 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEA06043.1 - 0.03 13.8 0.0 0.067 12.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Sugar_tr PF00083.19 EEA06044.1 - 9.7e-22 77.1 34.9 9.5e-13 47.5 9.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA06044.1 - 6.5e-07 28.3 18.3 6.5e-07 28.3 12.7 3.0 2 2 0 2 2 2 2 Major Facilitator Superfamily HCMV_UL139 PF12507.3 EEA06045.1 - 0.058 13.5 3.8 0.068 13.3 1.0 2.3 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Lipoprotein_3 PF00938.12 EEA06045.1 - 9.1 6.1 10.4 0.27 11.0 1.2 2.9 3 1 1 4 4 4 0 Lipoprotein DUF1443 PF07280.6 EEA06046.1 - 0.53 9.8 10.3 0.76 9.4 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1443) ketoacyl-synt PF00109.21 EEA06047.1 - 0 1592.2 0.0 4.5e-75 252.3 0.0 7.6 8 0 0 8 8 8 7 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA06047.1 - 1.6e-246 802.2 7.2 1.1e-38 131.7 0.0 7.7 7 0 0 7 7 7 7 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EEA06047.1 - 7.2e-191 628.6 0.0 6.9e-47 159.4 0.0 5.8 5 0 0 5 5 5 5 KR domain adh_short PF00106.20 EEA06047.1 - 3e-152 502.2 0.0 1.4e-37 129.2 0.0 6.5 6 0 0 6 6 6 5 short chain dehydrogenase Acyl_transf_1 PF00698.16 EEA06047.1 - 5.2e-106 354.5 0.0 1.5e-51 175.6 0.0 3.3 3 0 0 3 3 3 3 Acyl transferase domain PP-binding PF00550.20 EEA06047.1 - 2.1e-90 296.9 23.1 1.6e-12 47.5 0.1 9.6 9 0 0 9 9 8 8 Phosphopantetheine attachment site PS-DH PF14765.1 EEA06047.1 - 1.3e-83 280.5 0.0 5.4e-33 114.4 0.0 5.1 4 1 0 4 4 4 4 Polyketide synthase dehydratase AMP-binding PF00501.23 EEA06047.1 - 3.6e-62 210.1 0.0 1.7e-61 207.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 EEA06047.1 - 1.4e-60 202.5 0.0 6.5e-14 51.6 0.0 4.8 4 0 0 4 4 4 4 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 EEA06047.1 - 2.9e-57 193.4 0.0 7.4e-53 179.0 0.0 4.3 5 0 0 5 5 5 1 Male sterility protein ADH_N PF08240.7 EEA06047.1 - 7.5e-25 86.8 10.6 1.4e-05 24.7 0.1 5.9 7 0 0 7 7 5 4 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EEA06047.1 - 1.8e-22 79.5 20.2 0.00079 18.4 0.1 7.5 7 0 0 7 7 7 7 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.1 EEA06047.1 - 1e-15 58.7 0.0 0.00022 22.1 0.0 5.1 4 1 0 4 4 4 2 Zinc-binding dehydrogenase Epimerase PF01370.16 EEA06047.1 - 3.1e-15 56.2 0.1 0.029 13.7 0.0 7.3 7 0 0 7 7 7 3 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA06047.1 - 1.5e-11 43.7 5.1 0.00023 20.1 0.0 5.3 5 0 0 5 5 5 3 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.16 EEA06047.1 - 1.4e-05 24.7 0.1 1.5 8.3 0.0 4.0 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III PF08545.5 EEA06047.1 - 2.3e-05 23.9 27.6 0.31 10.7 0.1 7.4 7 0 0 7 7 7 3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.1 EEA06047.1 - 0.0019 18.2 4.2 1.4 8.8 0.0 5.0 6 0 0 6 6 6 1 NADH(P)-binding DUF4197 PF13852.1 EEA06047.1 - 2.2 7.7 0.1 10 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) DNA_gyraseB_C PF00986.16 EEA06047.1 - 4.1 7.2 0.2 69 3.3 0.0 3.0 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus CDI PF02234.14 EEA06047.1 - 8.6 6.2 0.9 20 5.0 0.7 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Peptidase_M24 PF00557.19 EEA06048.1 - 5.6e-36 124.0 0.0 1.3e-35 122.8 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEA06048.1 - 7.6e-17 62.0 0.1 3.3e-15 56.7 0.0 2.9 3 1 0 3 3 3 1 Creatinase/Prolidase N-terminal domain DUF1160 PF06648.6 EEA06048.1 - 0.017 14.9 1.5 0.16 11.7 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1160) HALZ PF02183.13 EEA06049.1 - 0.0022 17.6 1.4 0.0022 17.6 1.0 6.5 6 2 1 7 7 7 2 Homeobox associated leucine zipper YscO PF07321.7 EEA06049.1 - 0.0034 17.2 3.1 0.0034 17.2 2.2 3.6 5 0 0 5 5 5 1 Type III secretion protein YscO DivIC PF04977.10 EEA06049.1 - 0.016 14.6 0.6 0.016 14.6 0.4 5.9 6 2 1 7 7 7 0 Septum formation initiator DUF972 PF06156.8 EEA06049.1 - 0.088 13.1 0.1 0.088 13.1 0.1 6.1 4 1 1 5 5 5 0 Protein of unknown function (DUF972) Vps52 PF04129.7 EEA06051.1 - 2.7e-20 72.4 34.3 1.6e-18 66.5 23.6 2.3 1 1 0 1 1 1 1 Vps52 / Sac2 family FlaC_arch PF05377.6 EEA06051.1 - 0.0067 16.2 3.4 0.024 14.5 2.3 1.9 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF3683 PF12447.3 EEA06051.1 - 0.048 13.4 0.3 12 5.7 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) Reo_sigmaC PF04582.7 EEA06051.1 - 0.16 11.0 2.9 0.085 12.0 0.5 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_11 PF13414.1 EEA06052.1 - 9.2e-12 44.4 6.0 6.2e-07 28.9 1.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA06052.1 - 5.7e-11 41.5 8.6 0.0018 17.8 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06052.1 - 6.3e-09 35.0 6.5 0.061 13.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA06052.1 - 7.4e-09 35.3 2.3 2.6e-05 23.9 0.1 2.7 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 EEA06052.1 - 2e-07 31.4 0.9 0.0025 18.4 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA06052.1 - 0.0005 20.1 12.3 0.0021 18.1 4.7 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EEA06052.1 - 0.00062 20.0 1.6 0.0041 17.4 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA06052.1 - 0.0055 17.2 0.1 6.4 7.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEA06052.1 - 0.0081 16.4 0.9 0.069 13.3 0.2 2.5 1 1 2 3 3 3 1 Alkyl sulfatase dimerisation TPR_7 PF13176.1 EEA06052.1 - 0.012 15.3 0.3 3.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06052.1 - 0.013 15.8 2.9 3.4 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06052.1 - 0.14 12.0 6.7 1.6 8.6 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06052.1 - 0.55 10.1 7.0 3.1 7.8 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06052.1 - 0.98 9.7 3.5 24 5.4 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat AP2 PF00847.15 EEA06053.1 - 1.3e-09 38.0 2.8 1.9e-08 34.3 0.2 2.5 1 1 1 2 2 2 2 AP2 domain ERCC4 PF02732.10 EEA06054.1 - 1.4e-22 79.9 1.4 1.2e-21 77.0 0.0 3.2 3 0 0 3 3 3 1 ERCC4 domain CRAL_TRIO_2 PF13716.1 EEA06055.1 - 2.4e-28 98.9 0.3 4.6e-28 97.9 0.2 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EEA06055.1 - 4e-14 52.4 0.0 8.1e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EEA06055.1 - 0.01 15.3 0.3 0.038 13.4 0.2 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain DEAD PF00270.24 EEA06056.1 - 2.8e-47 160.3 0.0 1.2e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06056.1 - 6.7e-29 99.5 0.1 2.3e-28 97.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fib_alpha PF08702.5 EEA06057.1 - 0.00027 21.0 22.4 0.022 14.8 6.6 2.3 1 1 0 2 2 2 2 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EEA06057.1 - 0.001 18.0 12.4 0.0014 17.6 7.6 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 EEA06057.1 - 0.0014 18.6 10.4 0.033 14.2 3.2 2.6 2 1 1 3 3 2 2 Flagellar FliJ protein WXG100 PF06013.7 EEA06057.1 - 0.0015 18.4 7.8 0.53 10.3 0.1 4.3 4 0 0 4 4 4 1 Proteins of 100 residues with WXG ATG16 PF08614.6 EEA06057.1 - 0.0041 16.9 15.1 0.0041 16.9 10.4 2.2 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Fez1 PF06818.10 EEA06057.1 - 0.0052 16.8 9.5 0.44 10.5 0.4 2.2 1 1 1 2 2 2 2 Fez1 DUF948 PF06103.6 EEA06057.1 - 0.012 15.4 9.6 0.037 13.8 0.5 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Rsm22 PF09243.5 EEA06057.1 - 0.019 13.9 1.4 0.035 13.1 1.0 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 AAA_27 PF13514.1 EEA06057.1 - 0.023 12.3 8.7 0.026 12.2 6.0 1.1 1 0 0 1 1 1 0 AAA domain RPW8 PF05659.6 EEA06057.1 - 0.032 13.7 6.9 0.076 12.5 0.2 3.2 1 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CENP-F_leu_zip PF10473.4 EEA06057.1 - 0.032 14.0 22.0 0.23 11.3 2.9 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EEA06057.1 - 0.036 13.2 11.2 0.03 13.5 2.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HrpB7 PF09486.5 EEA06057.1 - 0.036 14.0 0.1 0.088 12.7 0.1 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PEP-utilisers_N PF05524.8 EEA06057.1 - 0.036 13.8 1.8 0.23 11.2 0.4 2.5 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4413 PF14372.1 EEA06057.1 - 0.045 13.7 3.1 0.37 10.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4413) DUF2408 PF10303.4 EEA06057.1 - 0.051 13.6 12.9 0.49 10.5 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Spc7 PF08317.6 EEA06057.1 - 0.099 11.2 23.1 0.034 12.8 8.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DHC PF09626.5 EEA06057.1 - 0.13 12.9 6.6 0.22 12.1 0.3 2.5 2 1 1 3 3 2 0 Dihaem cytochrome c Cob_adeno_trans PF01923.13 EEA06057.1 - 0.13 12.0 5.6 1.6 8.4 0.6 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase CALCOCO1 PF07888.6 EEA06057.1 - 0.14 10.4 11.4 0.36 9.0 7.7 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Snapin_Pallidin PF14712.1 EEA06057.1 - 0.14 12.4 15.5 0.26 11.6 0.7 3.3 3 1 0 3 3 3 0 Snapin/Pallidin MtrB PF05440.7 EEA06057.1 - 0.16 12.0 2.8 0.84 9.7 0.1 2.8 3 0 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4164 PF13747.1 EEA06057.1 - 0.17 12.0 12.1 1.3 9.2 1.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) FtsQ PF03799.10 EEA06057.1 - 0.19 11.8 3.2 0.77 9.9 0.3 2.6 2 1 0 3 3 2 0 Cell division protein FtsQ Occludin_ELL PF07303.8 EEA06057.1 - 0.2 12.3 11.6 6.6 7.5 0.7 3.7 1 1 4 5 5 5 0 Occludin homology domain MCPsignal PF00015.16 EEA06057.1 - 0.24 10.9 10.5 2.3 7.7 1.0 2.5 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1732 PF08340.6 EEA06057.1 - 0.25 11.2 6.8 0.19 11.5 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) DUF2730 PF10805.3 EEA06057.1 - 0.3 10.8 5.5 3.6 7.3 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) Mnd1 PF03962.10 EEA06057.1 - 0.33 10.6 15.0 0.12 12.0 6.7 2.2 1 1 1 2 2 2 0 Mnd1 family Pox_A_type_inc PF04508.7 EEA06057.1 - 0.39 10.6 13.2 0.95 9.4 0.4 4.7 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.7 EEA06057.1 - 0.41 10.3 21.8 0.75 9.5 3.1 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EEA06057.1 - 0.42 10.8 14.8 0.86 9.8 0.7 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CDC37_N PF03234.9 EEA06057.1 - 0.53 10.5 19.0 0.65 10.2 3.2 2.9 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 EEA06057.1 - 0.54 10.7 4.4 1.8 9.0 0.3 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.7 EEA06057.1 - 0.57 9.9 20.7 0.29 10.8 1.9 2.8 2 1 1 3 3 3 0 Laminin Domain II APG6 PF04111.7 EEA06057.1 - 0.57 9.1 22.3 0.11 11.5 9.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 P4Ha_N PF08336.6 EEA06057.1 - 0.65 9.8 16.5 0.81 9.5 1.3 3.2 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1515 PF07439.6 EEA06057.1 - 0.72 9.6 2.8 1.6 8.5 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Syntaxin PF00804.20 EEA06057.1 - 0.78 9.9 18.6 0.35 11.0 5.7 2.6 1 1 1 2 2 2 0 Syntaxin THOC7 PF05615.8 EEA06057.1 - 0.84 9.8 12.7 2.9 8.1 2.4 2.8 1 1 1 2 2 2 0 Tho complex subunit 7 Rop-like PF05082.8 EEA06057.1 - 0.92 9.0 5.3 0.17 11.3 0.4 2.2 3 0 0 3 3 1 0 Rop-like FlaC_arch PF05377.6 EEA06057.1 - 1.1 9.2 22.3 0.71 9.8 3.4 4.0 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 EEA06057.1 - 1.1 7.0 16.3 0.39 8.5 2.3 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 EEA06057.1 - 1.2 8.6 18.0 0.66 9.5 10.1 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Med9 PF07544.8 EEA06057.1 - 1.3 8.8 11.7 6.2 6.6 0.1 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AATF-Che1 PF13339.1 EEA06057.1 - 1.4 9.1 16.8 1.5 8.9 4.5 3.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Tropomyosin_1 PF12718.2 EEA06057.1 - 1.5 8.7 22.0 0.32 10.8 11.9 2.3 2 1 0 2 2 2 0 Tropomyosin like Tropomyosin PF00261.15 EEA06057.1 - 2.2 7.3 19.3 0.82 8.7 9.3 2.3 2 1 1 3 3 2 0 Tropomyosin YtxH PF12732.2 EEA06057.1 - 2.2 8.7 8.1 8.9 6.7 1.0 2.9 1 1 1 2 2 2 0 YtxH-like protein DUF342 PF03961.8 EEA06057.1 - 2.4 6.4 19.7 0.71 8.2 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Erp_C PF06780.6 EEA06057.1 - 2.6 7.9 19.1 0.26 11.1 1.1 3.0 2 1 0 3 3 3 0 Erp protein C-terminus SlyX PF04102.7 EEA06057.1 - 2.6 8.4 10.4 14 6.1 0.6 3.7 1 1 2 3 3 3 0 SlyX Prefoldin_2 PF01920.15 EEA06057.1 - 2.8 7.7 20.1 6.9 6.4 3.6 3.9 1 1 0 3 3 3 0 Prefoldin subunit Uds1 PF15456.1 EEA06057.1 - 2.9 7.8 12.6 1.1 9.2 0.9 2.7 1 1 3 4 4 4 0 Up-regulated During Septation Cauli_AT PF03233.8 EEA06057.1 - 2.9 7.5 19.8 0.12 12.0 0.9 3.2 1 1 1 3 3 3 0 Aphid transmission protein Syntaxin-6_N PF09177.6 EEA06057.1 - 3.2 8.2 16.5 1.6 9.2 1.4 3.6 1 1 1 3 3 3 0 Syntaxin 6, N-terminal G10 PF01125.12 EEA06057.1 - 3.3 7.2 5.6 2 7.9 1.7 2.0 2 0 0 2 2 2 0 G10 protein Seryl_tRNA_N PF02403.17 EEA06057.1 - 3.6 7.6 25.6 0.26 11.3 3.8 4.0 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain L31 PF09784.4 EEA06057.1 - 4.9 7.2 5.9 3.1 7.8 0.1 2.7 2 2 0 2 2 2 0 Mitochondrial ribosomal protein L31 DASH_Dad3 PF08656.5 EEA06057.1 - 5.8 6.6 16.6 2.5 7.8 0.3 4.1 2 1 2 4 4 4 0 DASH complex subunit Dad3 Bap31 PF05529.7 EEA06057.1 - 6 6.2 11.6 0.27 10.6 2.0 2.4 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like COG2 PF06148.6 EEA06057.1 - 7.1 6.5 14.6 5.9 6.7 0.7 3.4 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Allexi_40kDa PF05549.6 EEA06057.1 - 8 5.6 13.8 1.6 7.9 3.2 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.7 EEA06057.1 - 8.4 6.2 15.2 5.6 6.7 1.3 3.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF2203 PF09969.4 EEA06057.1 - 8.6 6.6 11.3 1.3e+03 -0.5 7.8 3.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Vfa1 PF08432.5 EEA06057.1 - 9.9 6.1 13.2 3.2 7.7 6.6 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Abhydrolase_2 PF02230.11 EEA06058.1 - 0.0022 17.4 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EEA06058.1 - 0.0032 17.2 0.2 0.0069 16.1 0.1 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EEA06059.1 - 5.9e-05 22.6 0.0 0.00086 18.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA06059.1 - 0.00065 19.4 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_5 PF00266.14 EEA06060.1 - 6.4e-84 281.8 0.0 8.1e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEA06060.1 - 6.8e-07 28.7 0.0 8.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA06060.1 - 8.3e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EEA06060.1 - 0.00073 18.0 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EEA06060.1 - 0.0008 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_2 PF02230.11 EEA06061.1 - 1.9e-06 27.4 0.0 4.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA06061.1 - 0.0075 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEA06061.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 EEA06061.1 - 0.23 11.1 0.7 15 5.2 0.4 2.4 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal FeoB_C PF07664.7 EEA06062.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF3485 PF11984.3 EEA06062.1 - 0.076 12.0 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) UPF0542 PF15086.1 EEA06062.1 - 0.086 12.5 0.2 0.086 12.5 0.2 1.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF3899 PF13038.1 EEA06062.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) OAD_gamma PF04277.8 EEA06062.1 - 2.9 8.3 6.3 9.8 6.6 4.4 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PcfK PF14058.1 EEA06062.1 - 9.6 6.3 9.8 19 5.3 6.8 1.6 1 1 0 1 1 1 0 PcfK-like protein Ribosomal_S27 PF01599.14 EEA06063.1 - 1.5e-24 85.5 1.4 2.9e-24 84.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EEA06063.1 - 5.8e-06 25.6 0.0 2.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EEA06063.1 - 0.0016 18.6 0.8 0.02 15.1 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain IBR PF01485.16 EEA06063.1 - 0.0044 16.8 0.8 0.0063 16.3 0.5 1.3 1 0 0 1 1 1 1 IBR domain zf-C2H2_3 PF13878.1 EEA06063.1 - 0.045 13.3 1.0 0.085 12.4 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Fer2_3 PF13085.1 EEA06063.1 - 0.077 12.8 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain EB PF01683.13 EEA06064.1 - 9.5e-05 22.3 40.2 6 7.0 0.4 10.4 5 3 0 5 5 5 3 EB module CPW_WPC PF09717.5 EEA06064.1 - 0.37 11.4 39.2 11 6.7 0.2 10.6 6 5 3 10 10 10 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Prok-E2_C PF14459.1 EEA06064.1 - 0.45 10.6 1.6 4.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Prokaryotic E2 family C cEGF PF12662.2 EEA06064.1 - 0.56 9.9 76.3 1 9.0 0.5 15.2 14 2 1 15 15 15 0 Complement Clr-like EGF-like Calcyon PF06387.6 EEA06064.1 - 1.7 7.9 27.2 1.7 8.0 0.0 7.8 8 2 2 10 10 10 0 D1 dopamine receptor-interacting protein (calcyon) Guanylate_cyc PF00211.15 EEA06065.1 - 4.4e-20 71.8 0.0 1.6e-08 34.1 0.0 3.5 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain TPT PF03151.11 EEA06066.1 - 1.3e-24 86.6 29.7 1e-19 70.6 8.4 3.4 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EEA06066.1 - 2.8e-07 29.7 19.1 2.8e-07 29.7 13.3 1.9 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EEA06066.1 - 2e-05 24.6 26.8 0.001 19.1 1.9 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nucleos_tra2_C PF07662.8 EEA06066.1 - 0.00048 19.6 0.0 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus UPF0546 PF10639.4 EEA06066.1 - 0.012 15.4 0.8 0.012 15.4 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF2627 PF11118.3 EEA06066.1 - 0.67 10.0 8.7 1.6 8.8 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) EmrE PF13536.1 EEA06066.1 - 6.1 7.0 25.1 0.041 14.0 1.2 3.2 3 0 0 3 3 3 0 Multidrug resistance efflux transporter eIF-6 PF01912.13 EEA06067.1 - 3.7e-79 264.4 2.2 5.2e-79 263.9 1.2 1.4 1 1 1 2 2 2 1 eIF-6 family DUF2344 PF10105.4 EEA06067.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) WD40 PF00400.27 EEA06068.1 - 9.6e-40 133.0 12.8 9e-11 41.2 0.8 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat IKI3 PF04762.7 EEA06068.1 - 0.032 12.0 0.3 0.54 7.9 0.0 2.4 1 1 2 3 3 3 0 IKI3 family BBS2_Mid PF14783.1 EEA06068.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Cas_CXXC_CXXC PF09706.5 EEA06068.1 - 0.072 13.2 0.2 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Nucleoporin_N PF08801.6 EEA06068.1 - 0.57 8.8 4.8 11 4.5 0.2 3.1 1 1 1 2 2 2 0 Nup133 N terminal like Cullin PF00888.17 EEA06069.1 - 6.6e-115 384.8 26.1 6.7e-114 381.5 14.2 2.0 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EEA06069.1 - 3.5e-25 87.6 2.0 3.5e-25 87.6 1.4 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain EMP24_GP25L PF01105.19 EEA06069.1 - 0.012 15.3 3.5 0.025 14.3 1.5 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Ribosomal_S3Ae PF01015.13 EEA06070.1 - 8.7e-78 260.1 1.1 1e-77 259.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EEA06070.1 - 0.011 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Oxidored_molyb PF00174.14 EEA06070.1 - 0.083 12.3 0.1 0.63 9.4 0.1 2.1 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Tim17 PF02466.14 EEA06072.1 - 3e-15 56.3 5.6 3.9e-15 56.0 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DEAD PF00270.24 EEA06073.1 - 8.7e-47 158.7 0.1 1.6e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06073.1 - 5.1e-26 90.3 0.1 1.2e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA06073.1 - 0.00072 19.4 0.0 0.0023 17.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEA06073.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain LSM PF01423.17 EEA06074.1 - 4.4e-18 64.5 0.7 6.6e-18 64.0 0.5 1.3 1 0 0 1 1 1 1 LSM domain XLF PF09302.6 EEA06074.1 - 0.041 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 XLF (XRCC4-like factor) DNAJ_related PF12339.3 EEA06075.1 - 0.014 15.2 0.6 0.037 13.9 0.3 1.7 1 1 1 2 2 2 0 DNA-J related protein Med11 PF10280.4 EEA06075.1 - 0.02 14.9 1.7 0.025 14.6 1.1 1.2 1 0 0 1 1 1 0 Mediator complex protein TBCA PF02970.11 EEA06075.1 - 0.043 13.8 1.0 0.13 12.3 0.2 2.0 1 1 0 2 2 2 0 Tubulin binding cofactor A SYCE1 PF15233.1 EEA06075.1 - 0.09 12.6 1.9 0.12 12.3 1.4 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 TFIIE_alpha PF02002.12 EEA06075.1 - 0.16 11.5 2.9 0.19 11.2 2.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit Allexi_40kDa PF05549.6 EEA06075.1 - 0.68 9.1 3.7 0.78 8.9 2.6 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein AAA_12 PF13087.1 EEA06076.1 - 8.1e-35 120.0 0.0 2.1e-34 118.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA06076.1 - 3.2e-25 89.0 0.1 5.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA06076.1 - 9.9e-09 34.8 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA06076.1 - 1e-06 28.4 0.0 1.6e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EEA06076.1 - 2.5e-06 27.0 0.1 0.00053 19.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA06076.1 - 2.9e-05 24.2 0.0 0.0004 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEA06076.1 - 0.00016 20.7 0.2 0.00045 19.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEA06076.1 - 0.00027 20.2 0.0 0.00096 18.4 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EEA06076.1 - 0.00096 19.9 0.4 0.67 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEA06076.1 - 0.0017 17.3 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Parvo_NS1 PF01057.12 EEA06076.1 - 0.0022 16.9 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.24 EEA06076.1 - 0.0048 17.0 0.1 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 EEA06076.1 - 0.0065 16.1 0.0 0.052 13.1 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_18 PF13238.1 EEA06076.1 - 0.015 15.5 0.0 0.12 12.7 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA06076.1 - 0.039 13.8 3.1 0.18 11.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 EEA06076.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EEA06076.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEA06076.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA06076.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EEA06076.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEA06076.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_L_2 PF13656.1 EEA06077.1 - 2.9e-22 77.8 0.1 3.5e-21 74.4 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEA06077.1 - 7.6e-07 28.1 0.0 1.4e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1955 PF09205.5 EEA06077.1 - 0.0021 17.6 0.2 0.0032 17.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1955) Kdo PF06293.9 EEA06078.1 - 0.048 12.7 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Histone PF00125.19 EEA06079.1 - 2.6e-32 110.7 0.4 3.9e-32 110.1 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA06079.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEA06079.1 - 0.031 14.3 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NIF PF03031.13 EEA06081.1 - 1.3e-40 138.6 0.2 3e-40 137.4 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase MSG PF02349.10 EEA06081.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 Major surface glycoprotein TRM PF02005.11 EEA06082.1 - 1.8e-89 300.2 0.1 6e-67 226.1 0.0 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EEA06082.1 - 0.0037 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_N PF01194.12 EEA06083.1 - 1.1e-29 102.1 0.3 1.4e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EEA06083.1 - 0.18 11.9 0.8 0.33 11.0 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) HSP70 PF00012.15 EEA06084.1 - 2.8e-112 375.6 0.0 4.4e-112 374.9 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA06084.1 - 6.3e-09 34.8 0.7 2.6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEA06084.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GATA PF00320.22 EEA06085.1 - 0.047 13.0 10.4 0.042 13.2 1.8 2.6 2 0 0 2 2 2 0 GATA zinc finger WWE PF02825.15 EEA06085.1 - 0.058 12.8 0.4 0.43 10.0 0.1 2.2 2 0 0 2 2 2 0 WWE domain Sod_Fe_C PF02777.13 EEA06085.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain IMCp PF12314.3 EEA06086.1 - 7.9e-12 45.1 33.5 7.9e-12 45.1 23.2 3.5 2 1 1 3 3 3 2 Inner membrane complex protein IMCp PF12314.3 EEA06087.1 - 6.9e-10 38.9 32.6 3.6e-08 33.4 14.6 4.2 3 2 1 4 4 4 2 Inner membrane complex protein Cuticle_3 PF11018.3 EEA06087.1 - 0.0095 16.0 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 Pupal cuticle protein C1 Caps_synth_GfcC PF06251.6 EEA06087.1 - 0.074 12.2 7.4 0.11 11.6 5.1 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC PGM_PMM_I PF02878.11 EEA06088.1 - 2.6e-12 46.3 0.0 2e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEA06088.1 - 5.9e-08 32.9 0.0 2e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA06088.1 - 7.5e-06 25.8 0.0 2.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NOC3p PF07540.6 EEA06090.1 - 7.6e-15 54.9 0.6 3.7e-14 52.7 0.1 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein Pkinase PF00069.20 EEA06091.1 - 6.5e-69 231.9 0.9 9.3e-69 231.4 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06091.1 - 2.5e-41 141.4 0.7 3.7e-41 140.9 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EEA06091.1 - 6.5e-34 115.8 12.7 2.4e-11 43.5 0.7 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EEA06091.1 - 1.6e-32 108.2 12.2 3.2e-06 26.0 0.1 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.1 EEA06091.1 - 9.9e-27 90.4 9.5 1.5e-05 24.4 0.0 6.9 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.1 EEA06091.1 - 5.1e-22 76.1 14.8 2.3e-06 26.6 0.3 6.5 6 0 0 6 6 6 6 EF hand EF-hand_8 PF13833.1 EEA06091.1 - 9.9e-22 76.3 14.6 3.4e-05 23.3 0.0 6.8 4 3 3 7 7 7 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEA06091.1 - 1.4e-09 37.9 0.8 0.00048 20.1 0.0 3.6 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pox_ser-thr_kin PF05445.6 EEA06091.1 - 7.8e-06 24.9 1.9 1.5e-05 24.0 1.3 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEA06091.1 - 9.7e-06 24.7 0.3 1.9e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA06091.1 - 1.4e-05 24.1 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like EF-hand_10 PF14788.1 EEA06091.1 - 9.2e-05 22.0 0.4 0.0088 15.6 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_4 PF12763.2 EEA06091.1 - 0.003 17.2 5.0 7 6.4 0.0 4.2 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 EEA06091.1 - 0.0032 17.4 2.6 9.3 6.3 0.2 4.4 4 1 0 4 4 4 0 Phosphoinositide-specific phospholipase C, efhand-like APH PF01636.18 EEA06091.1 - 0.0058 16.4 0.1 0.87 9.2 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEA06091.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Caleosin PF05042.8 EEA06091.1 - 0.066 12.7 0.2 0.9 9.0 0.0 2.8 3 0 0 3 3 3 0 Caleosin related protein PH PF00169.24 EEA06092.1 - 7.5e-07 29.3 0.7 9.7e-06 25.7 0.0 3.0 3 2 0 3 3 3 1 PH domain PH_11 PF15413.1 EEA06092.1 - 9e-05 22.7 1.9 0.0038 17.4 0.4 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EEA06092.1 - 0.0017 18.3 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EEA06092.1 - 0.0025 17.8 0.0 0.0093 16.0 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Mob1_phocein PF03637.12 EEA06093.1 - 6.7e-36 123.5 1.8 9.7e-36 123.0 1.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family WD40 PF00400.27 EEA06094.1 - 2.3e-20 71.6 5.2 2.9e-08 33.2 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA06094.1 - 2.4e-18 65.7 0.2 3.3e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EEA06094.1 - 7.4e-05 22.5 0.6 0.00019 21.1 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Beach PF02138.13 EEA06097.1 - 1.4e-70 237.8 5.4 1.5e-65 221.3 2.6 2.5 2 0 0 2 2 2 2 Beige/BEACH domain AMP-binding PF00501.23 EEA06098.1 - 1.6e-66 224.4 0.0 2.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.17 EEA06099.1 - 2.9e-50 167.7 0.3 4.5e-16 58.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06099.1 - 4.3e-34 116.3 0.2 3.3e-12 46.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06099.1 - 3.1e-27 94.1 0.5 4.3e-10 39.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 EEA06099.1 - 6.2e-10 38.7 1.6 1.4e-09 37.6 1.1 1.6 1 0 0 1 1 1 1 WW domain Nup35_RRM PF05172.8 EEA06099.1 - 0.028 14.1 0.6 0.16 11.7 0.1 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1264 PF06884.6 EEA06099.1 - 0.12 11.7 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1264) Vps53_N PF04100.7 EEA06100.1 - 3.8e-37 127.9 35.9 9.4e-21 74.0 5.0 4.7 3 1 0 4 4 4 2 Vps53-like, N-terminal DUF489 PF04356.7 EEA06100.1 - 0.016 14.8 0.4 0.067 12.7 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Snapin_Pallidin PF14712.1 EEA06100.1 - 0.059 13.6 6.8 0.42 10.9 0.0 3.9 3 1 0 3 3 3 0 Snapin/Pallidin PD40 PF07676.7 EEA06102.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF4448 PF14610.1 EEA06105.1 - 0.054 12.9 0.2 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EEA06105.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Racemase_4 PF13615.1 EEA06107.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Putative alanine racemase GRDA PF04723.9 EEA06111.1 - 0.21 11.2 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A DUF4298 PF14131.1 EEA06111.1 - 0.38 10.6 0.0 0.38 10.6 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4298) C_tripleX PF02363.14 EEA06112.1 - 3.7 7.8 11.9 0.96 9.6 4.0 2.8 2 0 0 2 2 2 0 Cysteine rich repeat DUF2556 PF10831.3 EEA06113.1 - 0.34 10.5 0.1 0.34 10.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Fcf2 PF08698.6 EEA06114.1 - 1 9.4 7.2 0.37 10.8 0.4 2.6 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing IF2_N PF04760.10 EEA06119.1 - 0.014 14.9 0.2 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MRP-S26 PF14943.1 EEA06119.1 - 0.022 14.3 1.5 0.026 14.0 1.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Nop25 PF09805.4 EEA06119.1 - 0.21 11.6 3.4 0.22 11.6 2.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Pkinase PF00069.20 EEA06120.1 - 3.5e-37 127.9 0.1 4.8e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06120.1 - 1.3e-11 44.0 0.0 1e-10 41.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA06120.1 - 0.056 12.3 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Latarcin PF10279.4 EEA06120.1 - 0.074 13.2 2.2 0.075 13.2 0.3 2.0 2 0 0 2 2 2 0 Latarcin precursor Aconitase PF00330.15 EEA06121.1 - 6.2e-128 427.1 0.0 8.1e-128 426.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEA06121.1 - 7.3e-36 123.1 0.0 1.6e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain TPR_11 PF13414.1 EEA06122.1 - 1.6e-09 37.2 0.8 8.1e-07 28.5 0.0 2.6 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEA06122.1 - 7.8e-06 25.4 3.0 0.028 14.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06122.1 - 0.00036 20.0 3.8 0.18 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06122.1 - 0.0069 16.6 0.2 0.29 11.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-C4H2 PF10146.4 EEA06122.1 - 0.062 13.3 6.3 1.9 8.4 4.0 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein TPR_16 PF13432.1 EEA06122.1 - 0.064 13.9 0.0 19 6.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat BCNT PF07572.7 EEA06123.1 - 7.3e-20 70.7 1.5 7.3e-20 70.7 1.0 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF4484 PF14831.1 EEA06123.1 - 0.12 12.5 10.6 0.083 12.9 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) MTS PF05175.9 EEA06124.1 - 8.8e-11 41.4 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EEA06124.1 - 6e-09 35.6 0.1 8.5e-09 35.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA06124.1 - 5.6e-08 32.8 0.0 6.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA06124.1 - 0.00031 21.0 0.0 0.00063 20.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA06124.1 - 0.0004 20.9 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA06124.1 - 0.00067 20.0 0.0 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EEA06124.1 - 0.0069 15.5 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EEA06124.1 - 0.0074 15.9 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEA06124.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 eIF-3c_N PF05470.7 EEA06126.1 - 3.6e-119 398.5 26.4 1.2e-68 231.6 3.4 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EEA06126.1 - 8.7e-10 38.8 0.1 1.9e-08 34.5 0.0 2.8 2 0 0 2 2 2 1 PCI domain CotJB PF12652.2 EEA06126.1 - 0.092 12.8 0.9 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 CotJB protein RhoGEF PF00621.15 EEA06127.1 - 0.019 14.8 1.8 0.025 14.4 1.3 1.3 1 1 0 1 1 1 0 RhoGEF domain DUF3508 PF12018.3 EEA06127.1 - 0.063 12.2 1.6 0.096 11.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Spore_III_AB PF09548.5 EEA06127.1 - 0.12 12.1 1.0 0.52 10.0 0.7 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Kunitz_BPTI PF00014.18 EEA06128.1 - 0.0087 16.2 0.1 3.3 7.9 0.0 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Methyltransf_8 PF05148.10 EEA06129.1 - 2.6e-50 171.1 0.6 9.2e-50 169.2 0.0 1.9 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EEA06129.1 - 9.5e-07 29.2 0.0 2.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA06129.1 - 0.00056 19.6 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA06129.1 - 0.00065 19.3 4.4 0.29 10.7 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain MTS PF05175.9 EEA06129.1 - 0.0024 17.2 0.2 0.28 10.5 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.13 EEA06129.1 - 0.07 12.2 0.7 0.14 11.2 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family TFIIE_alpha PF02002.12 EEA06130.1 - 0.00012 21.5 0.9 0.016 14.7 0.1 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit HTH_11 PF08279.7 EEA06130.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain DUF4428 PF14471.1 EEA06130.1 - 0.011 15.3 0.2 0.035 13.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Peptidase_C6 PF00851.13 EEA06130.1 - 0.037 12.6 1.5 0.046 12.3 0.4 1.5 1 1 0 1 1 1 0 Helper component proteinase zf-met PF12874.2 EEA06130.1 - 0.27 11.4 1.4 0.65 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA06130.1 - 0.29 11.1 1.4 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EEA06130.1 - 0.51 10.1 2.5 3.7 7.3 0.0 2.6 1 1 1 2 2 2 0 BED zinc finger AP2 PF00847.15 EEA06131.1 - 1.4e-07 31.5 1.5 3.5e-07 30.2 0.4 2.2 2 0 0 2 2 2 1 AP2 domain Ank_2 PF12796.2 EEA06132.1 - 5.5e-24 84.3 0.1 1.3e-12 47.8 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA06132.1 - 1.6e-21 74.9 0.1 4.4e-05 23.0 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 EEA06132.1 - 1.8e-15 55.4 0.2 0.00039 20.3 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EEA06132.1 - 2.4e-15 56.5 1.4 5.7e-07 29.8 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA06132.1 - 4.8e-11 42.5 0.2 6.3e-05 23.0 0.0 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA06133.1 - 1.9e-15 56.9 0.6 9.8e-12 45.0 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA06133.1 - 1.5e-11 43.5 0.3 4.8e-05 22.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEA06133.1 - 3.3e-11 43.3 0.5 2e-08 34.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA06133.1 - 2.2e-10 39.7 2.1 0.0028 17.7 0.0 6.0 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EEA06133.1 - 6.5e-09 35.7 0.2 0.00069 19.7 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Cpn60_TCP1 PF00118.19 EEA06134.1 - 2.1e-155 518.0 1.1 2.5e-155 517.8 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EEA06134.1 - 0.058 12.6 0.0 0.99 8.6 0.0 2.6 3 0 0 3 3 3 0 DeoC/LacD family aldolase Cpn60_TCP1 PF00118.19 EEA06135.1 - 2.9e-147 491.1 2.8 3.4e-147 491.0 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UDP-g_GGTase PF06427.6 EEA06136.1 - 4e-06 26.2 0.3 1.8e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase tRNA_bind PF01588.15 EEA06137.1 - 4.5e-27 93.7 0.1 7.9e-27 92.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain DUF2989 PF11207.3 EEA06137.1 - 0.0051 16.2 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2989) GST_C_3 PF14497.1 EEA06137.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA06137.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EEA06138.1 - 2.6e-21 74.6 18.2 6e-06 25.9 1.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEA06138.1 - 0.0035 15.6 0.0 0.0058 14.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain BPL_C PF02237.12 EEA06138.1 - 0.15 11.7 0.6 0.45 10.2 0.4 1.8 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Es2 PF09751.4 EEA06139.1 - 1e-21 77.8 20.4 3.7e-11 43.0 8.1 3.0 2 1 1 3 3 3 3 Nuclear protein Es2 Ribosomal_L24e PF01246.15 EEA06140.1 - 8.5e-22 76.7 1.0 1.5e-21 76.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_L31 PF01197.13 EEA06140.1 - 0.0011 18.8 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 WWE PF02825.15 EEA06142.1 - 6.1e-06 25.5 0.1 1.5e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 WWE domain ZZ PF00569.12 EEA06144.1 - 4.3e-12 45.3 7.7 8.3e-12 44.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EEA06144.1 - 2.4e-07 30.6 3.9 6.4e-07 29.3 0.1 3.3 2 2 1 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA06144.1 - 0.00047 20.2 0.0 0.0019 18.2 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain MF_alpha_N PF05436.6 EEA06144.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus SF3b10 PF07189.6 EEA06145.1 - 1.9e-27 94.8 0.0 2.1e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) WD40 PF00400.27 EEA06146.1 - 1.7e-63 208.3 41.8 1.9e-09 37.0 0.0 9.9 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.6 EEA06146.1 - 3.7e-21 75.2 2.2 3.7e-21 75.2 1.5 2.0 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain His_Phos_2 PF00328.17 EEA06147.1 - 2.6e-22 79.6 0.1 4.1e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PAP_central PF04928.12 EEA06148.1 - 7.1e-110 365.7 0.1 9.9e-110 365.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EEA06148.1 - 1.2e-38 132.1 0.2 2.3e-38 131.1 0.2 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEA06148.1 - 2.8e-06 27.5 0.0 8.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain WD40 PF00400.27 EEA06150.1 - 6.1e-30 102.0 13.1 1.2e-09 37.6 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEA06150.1 - 0.032 12.3 2.0 3.4 5.6 0.0 3.4 3 1 0 4 4 4 0 Nucleoporin Nup120/160 PMM PF03332.8 EEA06151.1 - 1.7e-96 322.0 2.2 2e-96 321.8 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EEA06151.1 - 3.5e-11 43.1 0.7 1.1e-10 41.5 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EEA06151.1 - 0.077 12.4 0.2 17 4.8 0.0 2.8 2 1 1 3 3 3 0 Polynucleotide kinase 3 phosphatase HAD PF12710.2 EEA06151.1 - 0.32 11.1 2.1 4.7 7.3 0.9 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MCM PF00493.18 EEA06152.1 - 1.4e-126 421.8 0.0 2e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA06152.1 - 4.6e-11 43.2 0.0 4.6e-11 43.2 0.0 3.3 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA06152.1 - 8.4e-09 34.8 0.2 1.2e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA06152.1 - 4.4e-05 23.0 0.0 9.7e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA06152.1 - 7.1e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) zf-UDP PF14569.1 EEA06152.1 - 0.073 12.8 1.3 0.21 11.3 0.9 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Sigma54_activat PF00158.21 EEA06152.1 - 0.086 12.3 1.5 2.4 7.6 0.0 2.9 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_16 PF13191.1 EEA06152.1 - 0.93 9.4 3.0 8.5 6.3 0.0 3.3 2 2 1 4 4 4 0 AAA ATPase domain DUF1084 PF06454.6 EEA06153.1 - 6.5e-07 28.6 21.2 4.2e-05 22.7 9.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) RseC_MucC PF04246.7 EEA06153.1 - 0.18 11.3 2.5 12 5.4 0.1 2.8 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HECT PF00632.20 EEA06155.1 - 1.8e-47 162.0 0.2 1.8e-47 162.0 0.1 3.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 EEA06155.1 - 3e-06 27.4 7.2 4.1e-06 27.0 0.8 4.6 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA06155.1 - 0.00048 20.5 2.3 0.0036 17.7 0.2 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EEA06155.1 - 0.00049 19.7 3.8 0.02 14.6 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF2457 PF10446.4 EEA06155.1 - 1.9 7.1 11.6 3.1 6.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP-synt_ab PF00006.20 EEA06156.1 - 1.3e-107 358.1 0.0 2e-107 357.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA06156.1 - 5e-23 81.7 2.0 1.1e-22 80.6 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA06156.1 - 3.8e-14 52.6 1.8 5.9e-14 52.0 0.5 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EEA06156.1 - 0.056 13.3 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Coatomer_WDAD PF04053.9 EEA06157.1 - 9.8e-128 426.6 11.4 2.5e-127 425.3 3.3 2.4 2 1 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 EEA06157.1 - 2e-51 170.1 16.2 1.4e-11 43.8 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEA06157.1 - 0.0027 15.9 1.1 0.012 13.7 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 TPR_8 PF13181.1 EEA06157.1 - 0.018 14.7 0.3 0.11 12.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06157.1 - 0.069 12.7 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06157.1 - 0.098 12.3 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 TPR repeat UBA PF00627.26 EEA06158.1 - 1.6e-08 34.1 0.0 1.4e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.18 EEA06158.1 - 2.9e-06 26.5 0.0 6.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEA06158.1 - 0.0038 17.3 1.3 0.023 14.8 0.1 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Arabinose_Isome PF02610.10 EEA06158.1 - 0.0098 14.8 0.4 0.015 14.2 0.3 1.2 1 0 0 1 1 1 1 L-arabinose isomerase Endonuc-PvuII PF09225.5 EEA06160.1 - 0.032 13.9 0.8 0.05 13.2 0.5 1.4 1 0 0 1 1 1 0 Restriction endonuclease PvuII Pkinase PF00069.20 EEA06162.1 - 4.8e-60 202.8 0.0 1.1e-59 201.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06162.1 - 7.5e-41 139.9 0.0 1.7e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA06162.1 - 1.4e-07 30.7 0.0 3.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA06162.1 - 0.46 10.1 0.0 0.81 9.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_S10 PF00338.17 EEA06163.1 - 1.9e-30 104.5 0.2 2.4e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF59 PF01883.14 EEA06164.1 - 9.7e-08 31.9 0.2 9.3e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF59 DUF4231 PF14015.1 EEA06165.1 - 0.12 12.3 3.7 0.25 11.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SET PF00856.23 EEA06166.1 - 7.9e-19 68.5 2.7 2.9e-17 63.4 1.9 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EEA06166.1 - 1.3e-06 28.1 4.4 1.3e-06 28.1 3.1 4.4 5 0 0 5 5 5 1 MYND finger Coatomer_b_Cpla PF14806.1 EEA06166.1 - 0.023 14.4 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform TPR_12 PF13424.1 EEA06166.1 - 0.062 13.2 1.1 18 5.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EEA06167.1 - 9.7e-20 70.1 0.1 3.2e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA06167.1 - 6.1e-17 62.0 10.4 1.5e-10 41.2 0.1 3.6 2 1 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EEA06167.1 - 3.2e-06 26.8 0.1 0.0039 16.8 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family DUF836 PF05768.9 EEA06167.1 - 7.8e-05 22.8 0.5 0.019 15.2 0.0 3.1 2 1 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EEA06167.1 - 0.033 14.1 0.1 0.69 9.9 0.0 2.9 2 0 0 2 2 2 0 Glutaredoxin GRAM PF02893.15 EEA06169.1 - 0.014 14.8 0.1 0.035 13.6 0.1 1.6 1 0 0 1 1 1 0 GRAM domain VPS11_C PF12451.3 EEA06170.1 - 4.5 7.2 10.3 0.046 13.5 0.5 2.9 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal PH PF00169.24 EEA06171.1 - 0.055 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 PH domain CBM_14 PF01607.19 EEA06172.1 - 0.021 14.7 54.0 3 7.8 0.8 12.2 5 2 8 13 13 13 0 Chitin binding Peritrophin-A domain cEGF PF12662.2 EEA06172.1 - 0.047 13.3 19.7 7.9 6.2 0.0 7.7 9 0 0 9 9 9 0 Complement Clr-like EGF-like RRM_5 PF13893.1 EEA06173.1 - 4.2e-12 45.7 0.1 7.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA06173.1 - 1.8e-11 43.4 0.2 4.7e-11 42.1 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06173.1 - 8.1e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YoqO PF14037.1 EEA06173.1 - 0.036 14.1 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 YoqO-like protein dUTPase PF00692.14 EEA06174.1 - 1e-16 60.5 0.0 1.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF1674 PF07896.7 EEA06175.1 - 2.4e-11 43.6 0.3 2.8e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) JAB PF01398.16 EEA06176.1 - 2.8e-05 23.8 0.2 0.0003 20.5 0.1 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3582 PF12122.3 EEA06176.1 - 0.076 13.0 0.4 0.076 13.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3582) YqfQ PF14181.1 EEA06177.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 YqfQ-like protein Bromodomain PF00439.20 EEA06179.1 - 2.9e-19 68.7 1.3 4.2e-18 65.0 0.0 2.4 1 1 1 2 2 2 1 Bromodomain RRM_1 PF00076.17 EEA06180.1 - 7.7e-38 127.9 0.5 5.6e-16 57.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06180.1 - 1.7e-24 85.5 0.1 2.1e-10 40.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06180.1 - 2.5e-24 84.8 0.4 2.5e-07 30.4 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EEA06180.1 - 0.00017 21.7 0.0 0.00054 20.1 0.0 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Tyr_Deacylase PF02580.11 EEA06181.1 - 6.8e-41 139.6 0.0 7.6e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HAD PF12710.2 EEA06182.1 - 1.3e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_16 PF10294.4 EEA06183.1 - 1.1e-24 86.7 0.2 2.5e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ank_2 PF12796.2 EEA06183.1 - 1.1e-23 83.4 1.3 1.6e-15 57.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA06183.1 - 2.5e-17 61.7 2.9 2.2e-08 33.4 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EEA06183.1 - 2.3e-15 56.6 0.3 1.6e-11 44.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA06183.1 - 5e-14 51.0 1.2 6.7e-05 22.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EEA06183.1 - 2.1e-11 43.6 0.0 3.1e-05 24.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MTS PF05175.9 EEA06183.1 - 7.3e-06 25.4 0.0 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EEA06183.1 - 0.012 16.1 0.0 0.081 13.5 0.0 2.4 2 2 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EEA06183.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEA06183.1 - 0.066 13.5 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEA06183.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEA06183.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEA06183.1 - 0.13 11.8 4.2 1.7 8.2 0.1 3.6 4 0 0 4 4 4 0 Methyltransferase domain Drf_GBD PF06371.8 EEA06184.1 - 0.0086 15.4 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain EIF_2_alpha PF07541.7 EEA06185.1 - 2e-32 111.3 0.5 3e-31 107.4 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EEA06185.1 - 2.2e-12 46.8 0.7 2.2e-12 46.8 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain DUF3376 PF11856.3 EEA06185.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) DUF2703 PF10865.3 EEA06185.1 - 0.046 13.6 0.7 1.3 8.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) Myb_DNA-bind_4 PF13837.1 EEA06185.1 - 0.083 13.0 0.3 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SSrecog PF03531.9 EEA06186.1 - 2.4e-53 180.7 0.6 3.9e-53 180.0 0.4 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EEA06186.1 - 1.9e-25 88.6 2.6 5.2e-25 87.2 0.1 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Hint PF01079.15 EEA06187.1 - 1.8e-20 73.0 0.0 3.5e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.6 EEA06187.1 - 0.016 15.0 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Pretoxin HINT domain PPTA PF01239.17 EEA06188.1 - 2e-30 102.8 30.4 1.8e-08 33.3 0.3 6.5 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Ribosomal_L24e PF01246.15 EEA06189.1 - 9.6e-29 99.0 5.9 9.6e-29 99.0 4.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 EEA06189.1 - 0.0013 18.3 4.6 0.0032 17.0 3.2 1.7 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-PHD-like PF15446.1 EEA06189.1 - 0.0089 15.3 1.1 0.021 14.1 0.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Sec20 PF03908.8 EEA06190.1 - 0.031 13.9 0.8 0.064 12.9 0.6 1.5 1 0 0 1 1 1 0 Sec20 AAA_4 PF04326.9 EEA06192.1 - 0.013 15.5 0.8 0.049 13.7 0.3 2.1 1 1 0 1 1 1 0 Divergent AAA domain Glyco_transf_36 PF06165.6 EEA06192.1 - 0.027 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 36 LSM PF01423.17 EEA06193.1 - 9.8e-13 47.4 0.1 1.4e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain AKAP7_NLS PF10469.4 EEA06195.1 - 1.1e-28 100.4 0.8 2.4e-28 99.2 0.5 1.5 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.11 EEA06195.1 - 0.0023 17.8 0.3 2.3 8.2 0.0 3.7 2 2 1 3 3 3 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 EEA06195.1 - 0.13 11.9 0.0 0.47 10.1 0.0 1.7 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily SAE2 PF08573.5 EEA06196.1 - 4.7e-13 49.6 4.9 5.1e-11 43.1 0.1 3.1 1 1 2 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Herpes_BLRF2 PF05812.7 EEA06196.1 - 0.028 14.2 0.5 0.076 12.8 0.3 1.8 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein vWF_A PF12450.3 EEA06196.1 - 0.032 13.9 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor WD40 PF00400.27 EEA06198.1 - 7.5e-14 50.9 12.6 0.0029 17.4 0.4 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF1767 PF08585.7 EEA06199.1 - 2.3e-07 30.9 0.4 1.1e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) DUF2969 PF11184.3 EEA06199.1 - 1.7 8.7 5.2 11 6.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2969) DUF4519 PF15012.1 EEA06202.1 - 0.043 13.7 1.0 0.083 12.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF1426 PF07234.6 EEA06202.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Vps16_N PF04841.8 EEA06203.1 - 8.7e-44 149.6 0.2 3.8e-43 147.5 0.1 2.1 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 EEA06203.1 - 3.5e-24 85.3 6.1 4.9e-14 52.0 0.1 2.5 1 1 0 2 2 2 2 Vps16, C-terminal region Clathrin PF00637.15 EEA06203.1 - 0.0006 19.4 2.9 0.0027 17.3 1.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Prp18 PF02840.10 EEA06207.1 - 2e-55 186.6 1.2 2e-55 186.6 0.8 2.5 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EEA06207.1 - 7.6e-12 44.2 0.1 1.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like RNA_pol_N PF01194.12 EEA06207.1 - 0.038 14.0 0.4 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Peptidase_M15_2 PF05951.8 EEA06207.1 - 0.13 11.6 0.5 0.37 10.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) ALMT PF11744.3 EEA06207.1 - 2.7 6.5 5.9 2.6 6.6 1.8 2.0 1 1 0 2 2 2 0 Aluminium activated malate transporter Pinin_SDK_memA PF04696.8 EEA06207.1 - 5.7 6.5 15.8 0.027 14.0 2.7 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region GPS PF01825.16 EEA06208.1 - 0.00068 19.6 1.5 0.0021 18.1 0.7 2.1 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Methyltransf_31 PF13847.1 EEA06211.1 - 6.1e-12 45.3 13.1 5.6e-10 39.0 1.3 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEA06211.1 - 5.1e-11 43.1 0.0 7.2e-09 36.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 EEA06211.1 - 2e-06 26.9 2.1 1.1e-05 24.5 0.1 2.4 2 1 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_11 PF08241.7 EEA06211.1 - 2.3e-06 28.0 0.0 0.0016 18.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 EEA06211.1 - 0.00032 20.3 0.0 0.055 13.1 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA06211.1 - 0.00037 20.2 0.1 0.036 13.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA06211.1 - 0.0019 18.2 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain RRN3 PF05327.6 EEA06212.1 - 3.1e-21 75.1 4.7 5.2e-21 74.3 3.3 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.3 EEA06212.1 - 0.0017 18.5 1.5 0.0037 17.5 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) Gtr1_RagA PF04670.7 EEA06213.1 - 1.5e-82 276.2 2.6 1.8e-82 275.9 1.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EEA06213.1 - 4.3e-05 22.8 0.0 7.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA06213.1 - 6e-05 22.4 0.1 0.00041 19.7 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EEA06213.1 - 0.00027 20.8 0.0 0.00092 19.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEA06213.1 - 0.00062 20.2 0.0 0.0023 18.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EEA06213.1 - 0.018 15.3 0.2 0.044 14.0 0.1 2.0 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EEA06213.1 - 0.093 12.2 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP14 PF02290.10 EEA06214.1 - 4e-07 29.8 0.9 4.8e-07 29.6 0.6 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF4206 PF13901.1 EEA06214.1 - 0.0052 16.3 0.4 0.0061 16.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) bZIP_Maf PF03131.12 EEA06214.1 - 0.34 11.2 3.5 0.29 11.4 1.6 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor Abi_C PF14355.1 EEA06214.1 - 0.39 10.6 2.1 0.34 10.8 0.5 1.7 2 1 0 2 2 2 0 Abortive infection C-terminus Skp1_POZ PF03931.10 EEA06215.1 - 3e-06 27.2 0.3 1.8e-05 24.7 0.1 2.2 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain Kinesin PF00225.18 EEA06216.1 - 9.5e-108 359.8 0.4 9.5e-108 359.8 0.3 3.1 2 1 1 3 3 3 1 Kinesin motor domain Tropomyosin PF00261.15 EEA06216.1 - 0.0041 16.2 15.1 0.0041 16.2 10.5 3.7 3 1 0 4 4 4 2 Tropomyosin DUF869 PF05911.6 EEA06216.1 - 0.11 10.7 44.3 0.19 9.9 30.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) MCPsignal PF00015.16 EEA06216.1 - 5.2 6.5 19.0 0.7 9.3 6.3 3.3 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RCC1 PF00415.13 EEA06218.1 - 3.5e-78 257.6 18.2 8.6e-15 54.6 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA06218.1 - 5.5e-37 124.6 40.3 5.3e-08 32.2 0.1 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 EEA06218.1 - 0.00097 19.2 0.3 1.6 8.9 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF4213) RE_Bsp6I PF09504.5 EEA06218.1 - 0.031 13.7 0.9 0.42 10.0 0.2 2.4 2 0 0 2 2 2 0 Bsp6I restriction endonuclease PMC2NT PF08066.7 EEA06218.1 - 0.14 12.4 0.9 0.25 11.6 0.6 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain OTU PF02338.14 EEA06219.1 - 1.2e-19 71.0 0.3 1.2e-19 71.0 0.2 2.9 3 1 0 3 3 3 1 OTU-like cysteine protease RRM_1 PF00076.17 EEA06220.1 - 7e-17 60.8 0.0 1.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06220.1 - 6.3e-13 48.5 0.0 9.6e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06220.1 - 1.4e-09 37.6 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EEA06220.1 - 0.041 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 EEA06220.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NESP55 PF06390.7 EEA06221.1 - 0.14 11.4 4.7 0.19 11.0 3.3 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nucleoside_tran PF01733.13 EEA06221.1 - 7.2 5.6 6.4 15 4.6 1.8 2.6 2 1 1 3 3 3 0 Nucleoside transporter IncA PF04156.9 EEA06222.1 - 1.3 8.5 5.5 1.1 8.8 0.2 2.5 2 1 1 3 3 3 0 IncA protein TPX2_importin PF12214.3 EEA06223.1 - 1.2 9.1 11.5 1.1 9.3 0.2 3.7 2 2 0 4 4 4 0 Cell cycle regulated microtubule associated protein NTP_transf_2 PF01909.18 EEA06224.1 - 0.021 15.1 0.0 0.064 13.5 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain FKBP_C PF00254.23 EEA06225.1 - 2.2e-21 75.6 0.0 3.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 EEA06225.1 - 1.8e-07 31.2 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF3776 PF12618.3 EEA06225.1 - 0.072 13.6 0.6 0.15 12.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3776) DUF3699 PF12480.3 EEA06226.1 - 0.0096 15.5 1.3 5.2 6.7 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3699) Helicase_C_2 PF13307.1 EEA06228.1 - 1.5e-56 190.9 0.1 3.2e-56 189.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEA06228.1 - 3.2e-37 127.5 4.3 3.2e-37 127.5 3.0 3.8 4 1 0 4 4 4 1 DEAD_2 DEAD PF00270.24 EEA06228.1 - 1.6e-05 24.4 0.1 0.67 9.4 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EEA06228.1 - 2.8e-05 24.0 3.7 0.0003 20.6 0.1 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEA06228.1 - 0.024 13.8 0.2 7.6 5.6 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EEA06228.1 - 0.056 13.5 0.4 21 5.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.26 EEA06229.1 - 6.6e-29 99.4 1.0 1.2e-28 98.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Herpes_pp38 PF04846.8 EEA06231.1 - 0.24 10.7 0.0 0.58 9.5 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Motile_Sperm PF00635.21 EEA06232.1 - 4.4e-25 87.4 0.0 1.3e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF3595 PF12166.3 EEA06232.1 - 0.066 12.0 0.6 0.12 11.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3595) HALZ PF02183.13 EEA06232.1 - 0.37 10.5 3.8 0.64 9.7 2.6 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rad10 PF03834.9 EEA06233.1 - 3.2e-24 84.4 1.5 1.6e-23 82.1 1.3 1.9 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 EEA06233.1 - 6.5e-05 22.7 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EEA06233.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.18 EEA06233.1 - 0.04 13.6 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif AP2 PF00847.15 EEA06234.1 - 0.2 11.8 9.8 0.49 10.5 0.7 2.8 2 0 0 2 2 2 0 AP2 domain Prenyltrans_2 PF13249.1 EEA06234.1 - 5.2 7.5 9.4 0.47 10.8 2.1 2.6 3 1 0 3 3 3 0 Prenyltransferase-like MOZ_SAS PF01853.13 EEA06235.1 - 6.9e-73 243.9 0.2 1.4e-72 242.8 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEA06235.1 - 5e-11 42.1 0.2 1.3e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EEA06235.1 - 0.41 11.0 2.5 1.4 9.4 1.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type MORN PF02493.15 EEA06237.1 - 1e-89 289.1 95.6 1.2e-08 34.1 0.4 14.9 15 0 0 15 15 15 14 MORN repeat PA_decarbox PF05870.6 EEA06237.1 - 0.62 9.5 4.5 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) TAA-Trp-ring PF15401.1 EEA06237.1 - 2.1 8.6 7.2 0.56 10.4 0.7 2.9 2 1 1 3 3 3 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Nucleoporin_FG PF13634.1 EEA06238.1 - 0.00042 20.5 28.8 0.00042 20.5 20.0 5.4 1 1 2 3 3 3 1 Nucleoporin FG repeat region LUC7 PF03194.10 EEA06239.1 - 1.3e-57 195.2 6.5 2.1e-57 194.5 4.5 1.3 1 0 0 1 1 1 1 LUC7 N_terminus Baculo_IE-1 PF05290.6 EEA06239.1 - 1.3 8.7 5.6 21 4.8 0.1 2.9 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) IPPT PF01715.12 EEA06240.1 - 2.3e-53 180.8 1.0 2.9e-53 180.4 0.7 1.1 1 0 0 1 1 1 1 IPP transferase KTI12 PF08433.5 EEA06240.1 - 0.021 14.0 0.1 0.23 10.6 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPT PF01745.11 EEA06240.1 - 0.064 12.4 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.1 EEA06240.1 - 0.076 13.8 0.4 0.21 12.4 0.1 2.1 1 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEA06240.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Rpr2 PF04032.11 EEA06241.1 - 3.5e-06 26.7 9.4 3.5e-06 26.7 6.5 2.3 2 1 1 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain EST1 PF10374.4 EEA06241.1 - 0.0044 17.0 3.3 0.017 15.0 2.0 2.3 1 1 0 1 1 1 1 Telomerase activating protein Est1 IBV_3C PF03620.8 EEA06242.1 - 5.1 7.0 6.3 0.22 11.4 0.4 1.6 2 0 0 2 2 2 0 IBV 3C protein PPTA PF01239.17 EEA06243.1 - 4.9e-36 120.5 24.5 2e-08 33.2 0.5 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat SID-1_RNA_chan PF13965.1 EEA06244.1 - 0.0072 14.5 1.7 0.0085 14.3 1.1 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SKN1 PF03935.10 EEA06244.1 - 0.0074 14.4 0.2 0.008 14.3 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Chordopox_G3 PF06129.7 EEA06244.1 - 0.028 14.5 2.0 0.051 13.7 1.1 1.7 1 1 1 2 2 2 0 Chordopoxvirus G3 protein Neur_chan_memb PF02932.11 EEA06244.1 - 0.042 13.7 0.9 0.057 13.2 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region O-ag_pol_Wzy PF14296.1 EEA06244.1 - 0.053 12.0 0.4 0.075 11.5 0.3 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Cytochrom_C_asm PF01578.15 EEA06244.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF1049 PF06305.6 EEA06244.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Ctr PF04145.10 EEA06244.1 - 0.3 11.1 2.8 0.45 10.5 1.9 1.5 1 1 0 1 1 1 0 Ctr copper transporter family YebO PF13974.1 EEA06244.1 - 0.51 10.1 3.1 7.6 6.4 0.0 2.7 2 1 0 2 2 2 0 YebO-like protein YMF19 PF02326.10 EEA06244.1 - 0.93 10.0 5.6 2.1 8.9 2.2 2.2 1 1 1 2 2 2 0 Plant ATP synthase F0 FAM176 PF14851.1 EEA06244.1 - 1.5 8.5 5.0 0.85 9.2 2.1 1.6 1 1 1 2 2 2 0 FAM176 family Band_3_cyto PF07565.8 EEA06244.1 - 2.3 7.6 5.0 3.5 7.0 3.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain S1FA PF04689.8 EEA06244.1 - 3.8 7.4 8.3 0.17 11.7 0.7 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA MCPsignal PF00015.16 EEA06245.1 - 1.4 8.3 7.6 0.22 11.0 0.3 3.1 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HECT PF00632.20 EEA06246.1 - 7.8e-89 297.9 0.2 1.4e-88 297.1 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NOT2_3_5 PF04153.13 EEA06247.1 - 9.4e-23 80.5 1.8 9.4e-23 80.5 1.3 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Hemolysin_N PF12563.3 EEA06247.1 - 0.095 12.1 0.9 0.17 11.3 0.6 1.3 1 0 0 1 1 1 0 Hemolytic toxin N terminal Evr1_Alr PF04777.8 EEA06248.1 - 9.6e-11 41.4 0.1 2.8e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.15 EEA06248.1 - 3.7e-07 29.7 0.1 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EEA06248.1 - 0.012 15.1 0.7 0.02 14.4 0.5 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AhpC-TSA PF00578.16 EEA06248.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EEA06248.1 - 0.06 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 EEA06248.1 - 0.086 13.0 0.2 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain DUF35_N PF12172.3 EEA06248.1 - 3.4 7.6 5.0 0.86 9.5 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Alba PF01918.16 EEA06249.1 - 8.4e-11 41.3 0.0 1.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Alba Ribosomal_L21e PF01157.13 EEA06250.1 - 1.1e-36 124.5 2.7 1.4e-36 124.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 EEA06250.1 - 0.0084 14.3 0.0 0.0097 14.1 0.0 1.1 1 0 0 1 1 1 1 RNA replicase, beta-chain DUF1103 PF06513.6 EEA06250.1 - 0.04 13.2 0.2 0.053 12.9 0.2 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Phosphorylase PF00343.15 EEA06251.1 - 2.4e-301 1000.8 1.1 2.9e-301 1000.6 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase FlgM PF04316.8 EEA06251.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM NAC PF01849.13 EEA06253.1 - 2e-14 52.8 0.0 3.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NAC domain DUF2462 PF09495.5 EEA06254.1 - 0.0029 18.3 7.1 0.0046 17.6 4.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) SRR1 PF07985.7 EEA06255.1 - 3.7e-11 42.7 0.1 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 SRR1 Mak16 PF04874.9 EEA06255.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region CutA1 PF03091.10 EEA06256.1 - 1.5e-32 111.3 2.8 1.8e-32 111.0 1.9 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein RBD-FIP PF09457.5 EEA06256.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FIP domain PTSIIB_sorb PF03830.10 EEA06256.1 - 0.069 13.0 0.5 0.086 12.7 0.4 1.1 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Rsbr_N PF08678.5 EEA06256.1 - 0.36 10.7 2.2 0.24 11.2 0.2 1.6 2 0 0 2 2 2 0 Rsbr N terminal PHF5 PF03660.9 EEA06257.1 - 1.2e-47 160.4 14.4 1.3e-47 160.2 10.0 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 EEA06257.1 - 0.015 15.0 1.3 0.015 15.0 0.9 3.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 PolC_DP2 PF03833.8 EEA06257.1 - 0.17 9.5 7.9 0.18 9.4 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 EEA06257.1 - 1.4 8.8 15.5 3.7 7.4 8.5 2.7 1 1 2 3 3 3 0 Double zinc ribbon Fer4_8 PF13183.1 EEA06257.1 - 4.9 7.2 17.7 0.16 11.9 0.4 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Topoisom_bac PF01131.15 EEA06258.1 - 7e-95 318.2 0.0 8.7e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EEA06258.1 - 5.7e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF86 PF01934.12 EEA06258.1 - 0.00094 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF86 DZR PF12773.2 EEA06258.1 - 1.5 8.6 23.0 0.94 9.3 2.8 4.3 1 1 2 3 3 3 0 Double zinc ribbon mRNA_cap_enzyme PF01331.14 EEA06259.1 - 7.7e-36 123.5 1.0 1.9e-24 86.4 0.2 2.2 1 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EEA06259.1 - 3.5e-09 36.9 1.2 9.3e-09 35.5 0.0 2.3 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain Sec1 PF00995.18 EEA06260.1 - 3e-54 184.6 3.1 3.8e-54 184.2 2.1 1.1 1 0 0 1 1 1 1 Sec1 family DUF4322 PF14210.1 EEA06260.1 - 0.021 14.2 0.0 0.062 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) Mito_carr PF00153.22 EEA06261.1 - 1.2e-06 28.1 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 EEA06262.1 - 1.3e-35 121.0 3.1 5.2e-16 58.1 0.2 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EEA06263.1 - 0.017 13.8 51.5 0.01 14.5 21.1 3.5 2 1 1 3 3 3 0 Major Facilitator Superfamily WD40 PF00400.27 EEA06265.1 - 1e-07 31.5 5.6 0.018 14.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-HC5HC2H PF13771.1 EEA06265.1 - 9.1e-06 25.7 4.3 9.1e-06 25.7 3.0 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain Bromodomain PF00439.20 EEA06265.1 - 0.00013 21.7 0.1 0.00013 21.7 0.0 2.6 2 1 0 2 2 2 1 Bromodomain zf-HC5HC2H_2 PF13832.1 EEA06265.1 - 0.0011 18.9 5.7 0.0082 16.1 3.9 2.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain PAN_4 PF14295.1 EEA06266.1 - 0.0077 15.9 1.0 0.024 14.3 0.7 1.8 1 0 0 1 1 1 1 PAN domain PC_rep PF01851.17 EEA06267.1 - 0.0039 17.3 3.9 0.053 13.7 0.1 3.4 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Exo_endo_phos PF03372.18 EEA06268.1 - 4.7e-18 66.0 0.2 1.3e-16 61.2 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PIG-X PF08320.7 EEA06269.1 - 3.3e-08 33.0 3.2 2.6e-07 30.1 1.4 2.5 2 1 0 2 2 2 1 PIG-X / PBN1 DEAD PF00270.24 EEA06271.1 - 1.7e-43 148.0 0.0 7e-43 146.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06271.1 - 8.4e-19 67.2 0.0 2.3e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA06271.1 - 6.1e-13 48.1 0.1 2.3e-12 46.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA06271.1 - 0.00097 19.0 1.2 0.0049 16.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 EEA06272.1 - 8.5e-24 83.3 2.9 1.3e-12 47.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA06272.1 - 7.5e-22 77.1 3.2 9.1e-16 57.7 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEA06272.1 - 0.0062 16.3 3.3 0.14 12.0 0.2 3.4 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EEA06272.1 - 0.01 15.9 3.7 0.023 14.8 0.1 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain PHD PF00628.24 EEA06273.1 - 9.7e-05 21.9 4.2 9.7e-05 21.9 2.9 2.4 2 0 0 2 2 2 1 PHD-finger Diphthamide_syn PF01866.12 EEA06274.1 - 5.8e-63 212.9 0.0 1.1e-62 212.0 0.0 1.4 1 1 0 1 1 1 1 Putative diphthamide synthesis protein SAMP PF05924.6 EEA06274.1 - 0.27 10.4 1.4 0.73 9.0 0.1 2.2 2 0 0 2 2 2 0 SAMP Motif DUF3273 PF11677.3 EEA06275.1 - 1.7e-70 237.2 13.7 2.2e-70 236.9 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF3273 PF11677.3 EEA06276.1 - 4.4e-69 232.6 8.0 5e-69 232.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2593 PF10767.4 EEA06276.1 - 0.076 12.7 3.3 0.19 11.3 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2593) COX14 PF14880.1 EEA06276.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.3 4 0 0 4 4 4 0 Cytochrome oxidase c assembly LRR_4 PF12799.2 EEA06277.1 - 2.9e-06 26.7 25.1 0.017 14.7 0.3 6.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA06277.1 - 0.02 14.6 25.8 1 9.1 0.1 5.7 3 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EEA06277.1 - 0.037 14.0 23.8 0.34 11.1 0.4 7.4 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.28 EEA06277.1 - 0.15 12.1 33.2 1.8 8.9 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat F-box PF00646.28 EEA06277.1 - 0.19 11.4 4.5 0.37 10.4 0.0 3.6 4 0 0 4 4 4 0 F-box domain RabGAP-TBC PF00566.13 EEA06278.1 - 4.5e-53 179.8 3.2 4.5e-53 179.8 2.2 2.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GTP_EFTU PF00009.22 EEA06279.1 - 1.4e-31 109.4 0.1 1.4e-30 106.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEA06279.1 - 1.9e-16 59.8 3.0 2.2e-16 59.6 0.1 2.5 2 1 1 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEA06279.1 - 1.1e-15 57.5 1.2 2.4e-10 40.3 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEA06279.1 - 2.5e-09 36.6 0.1 7e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEA06279.1 - 3.9e-05 23.5 0.0 0.00034 20.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DIX PF00778.12 EEA06279.1 - 0.074 12.7 1.1 9.1 6.0 0.1 2.7 2 0 0 2 2 2 0 DIX domain Ribosomal_L5_C PF00673.16 EEA06280.1 - 9.7e-24 82.9 0.0 1.5e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEA06280.1 - 2.9e-20 71.7 1.1 2.9e-19 68.5 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 RRM_5 PF13893.1 EEA06281.1 - 3e-11 42.9 0.1 8.2e-11 41.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA06281.1 - 8.1e-11 41.3 0.3 1.7e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06281.1 - 8.9e-09 35.2 0.2 8.1e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EEA06281.1 - 0.0077 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Mito_fiss_reg PF05308.6 EEA06281.1 - 0.0078 15.6 4.3 0.013 14.8 3.0 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF4523 PF15023.1 EEA06281.1 - 0.015 14.8 1.5 0.042 13.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.1 EEA06281.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CbiD PF01888.12 EEA06281.1 - 0.07 12.0 0.3 0.097 11.6 0.2 1.1 1 0 0 1 1 1 0 CbiD Calcipressin PF04847.7 EEA06281.1 - 0.088 12.3 0.0 0.088 12.3 0.0 2.2 2 0 0 2 2 2 0 Calcipressin CAP_N PF01213.14 EEA06281.1 - 2.9 7.0 5.9 3.1 7.0 3.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NT-C2 PF10358.4 EEA06282.1 - 0.0012 18.3 2.4 0.0019 17.7 0.7 2.0 2 1 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ion_trans_2 PF07885.11 EEA06283.1 - 1.2e-12 47.3 1.1 1.2e-12 47.3 0.7 2.6 3 0 0 3 3 3 1 Ion channel BK_channel_a PF03493.13 EEA06283.1 - 6.2e-10 38.9 0.0 6.5e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Methyltrans_RNA PF04452.9 EEA06284.1 - 4.3e-35 120.8 0.0 3.3e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase cEGF PF12662.2 EEA06287.1 - 5.3e-18 64.3 149.9 0.55 9.9 0.1 32.3 31 1 0 31 31 31 27 Complement Clr-like EGF-like E1-E2_ATPase PF00122.15 EEA06289.1 - 0.0046 16.0 0.0 0.01 14.9 0.0 1.5 1 1 0 1 1 1 1 E1-E2 ATPase XRN_N PF03159.13 EEA06290.1 - 2.9e-89 298.5 0.0 7e-89 297.2 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF4344 PF14247.1 EEA06290.1 - 0.011 15.4 0.2 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Adaptin_N PF01602.15 EEA06291.1 - 1.2e-30 106.3 16.8 4.4e-17 61.6 0.1 4.2 2 1 0 3 3 3 3 Adaptin N terminal region Not1 PF04054.10 EEA06292.1 - 6.9e-110 367.4 9.5 1.2e-60 205.4 2.0 2.5 1 1 1 2 2 2 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EEA06292.1 - 1.9e-48 163.8 0.0 5.6e-48 162.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) adh_short PF00106.20 EEA06292.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase STT3 PF02516.9 EEA06294.1 - 2.6e-72 244.3 40.0 9e-72 242.5 27.7 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit BT1 PF03092.11 EEA06295.1 - 4.3e-71 239.8 18.4 6.3e-71 239.3 12.8 1.2 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EEA06295.1 - 7.4e-14 51.2 26.7 7.4e-14 51.2 18.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Methyltransf_10 PF05971.7 EEA06296.1 - 7.5e-61 205.8 2.1 3.2e-41 141.4 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 EEA06296.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA06296.1 - 0.0018 17.9 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA06296.1 - 0.0049 16.8 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA06296.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EEA06296.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ABC2_membrane_3 PF12698.2 EEA06299.1 - 0.002 17.2 1.3 0.0022 17.0 0.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein UPF0118 PF01594.11 EEA06299.1 - 0.071 12.0 0.4 0.097 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 YjeF_N PF03853.10 EEA06301.1 - 9.7e-28 96.8 0.0 1.2e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glycos_transf_2 PF00535.21 EEA06302.1 - 1.6e-19 70.2 0.0 3.7e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEA06302.1 - 5.1e-08 32.9 0.0 8.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 EEA06302.1 - 1.4e-05 25.1 1.8 0.0019 18.2 0.1 3.1 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EEA06302.1 - 9.6e-05 21.7 0.9 0.0003 20.2 0.6 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.3 EEA06302.1 - 0.015 14.4 0.0 0.097 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase (GlcNAc) Ribonuc_red_lgC PF02867.10 EEA06303.1 - 1.2e-218 727.0 0.0 1.6e-218 726.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EEA06303.1 - 1.3e-21 76.1 0.0 3e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EEA06303.1 - 2e-11 44.1 0.0 5.9e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EEA06303.1 - 0.0015 16.6 0.0 0.0022 16.1 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase ORC3_N PF07034.6 EEA06304.1 - 2.3e-08 33.4 0.0 6.8e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus CENP-Q PF13094.1 EEA06305.1 - 8.3 6.4 22.5 2.6 8.0 12.2 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Kinesin PF00225.18 EEA06306.1 - 5.1e-96 321.2 3.8 5.1e-96 321.2 2.6 2.8 3 1 1 4 4 4 1 Kinesin motor domain Pox_A_type_inc PF04508.7 EEA06306.1 - 0.093 12.5 3.1 1.7 8.6 0.0 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Inhibitor_I42 PF09394.5 EEA06307.1 - 7.9e-21 74.1 0.1 1.7e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Chagasin family peptidase inhibitor I42 Sec7 PF01369.15 EEA06307.1 - 0.47 10.0 2.5 0.65 9.6 1.8 1.1 1 0 0 1 1 1 0 Sec7 domain Kinesin PF00225.18 EEA06308.1 - 8.5e-65 218.6 0.1 8.5e-65 218.6 0.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain DUF1764 PF08576.5 EEA06309.1 - 7.9e-22 77.9 1.1 9.2e-22 77.7 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Filament PF00038.16 EEA06309.1 - 0.0012 18.4 0.8 0.0015 18.0 0.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein Cortex-I_coil PF09304.5 EEA06309.1 - 0.039 14.0 1.6 0.087 12.8 1.1 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil BCIP PF13862.1 EEA06310.1 - 3.4e-41 140.9 1.9 4.9e-41 140.3 1.3 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SRP19 PF01922.12 EEA06311.1 - 3.8e-22 78.6 0.0 4.9e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein SR-25 PF10500.4 EEA06311.1 - 0.1 12.0 5.4 0.13 11.7 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein APC10 PF03256.11 EEA06312.1 - 2.2e-55 187.3 0.1 2.8e-55 186.9 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EEA06312.1 - 0.00047 19.9 0.1 0.00068 19.4 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain DUF21 PF01595.15 EEA06313.1 - 1.7e-33 115.4 2.5 2.9e-33 114.7 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EEA06313.1 - 0.0045 16.7 0.3 3.5 7.5 0.0 3.2 2 1 0 2 2 2 2 CBS domain YrhC PF14143.1 EEA06313.1 - 0.13 12.1 1.3 0.34 10.8 0.9 1.7 1 0 0 1 1 1 0 YrhC-like protein D123 PF07065.9 EEA06314.1 - 1.8e-36 125.7 9.0 1.8e-35 122.5 4.5 2.2 1 1 1 2 2 2 2 D123 Ribosomal_L28e PF01778.12 EEA06315.1 - 1.8e-26 92.8 1.3 1.9e-26 92.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EEA06315.1 - 1.6e-14 53.7 9.9 1.6e-14 53.7 6.8 1.9 1 1 1 2 2 2 1 Mak16 protein C-terminal region DUF2265 PF10023.4 EEA06315.1 - 0.047 12.8 1.5 0.65 9.0 0.0 2.0 1 1 1 2 2 2 0 Predicted aminopeptidase (DUF2265) Acetyltransf_1 PF00583.19 EEA06317.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEA06317.1 - 0.012 15.6 0.1 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA06317.1 - 0.018 15.2 0.2 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA06317.1 - 0.02 15.0 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HEAT_2 PF13646.1 EEA06318.1 - 0.00013 22.2 0.0 0.0012 19.1 0.0 2.3 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EEA06318.1 - 0.0074 16.2 0.2 7.4 6.9 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat DEAD PF00270.24 EEA06319.1 - 6.4e-24 84.3 0.0 1.6e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06319.1 - 3.5e-20 71.6 0.0 1e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T4_gp9_10 PF07880.6 EEA06319.1 - 0.073 12.1 0.4 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage T4 gp9/10-like protein Metallothio_11 PF02066.10 EEA06319.1 - 0.23 11.3 3.1 0.67 9.8 2.1 1.8 1 0 0 1 1 1 0 Metallothionein family 11 Rtf2 PF04641.7 EEA06320.1 - 1.4e-09 37.5 0.3 2.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 2 Rtf2 RING-finger zf-Nse PF11789.3 EEA06320.1 - 0.0003 20.2 0.3 0.0067 15.9 0.3 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EEA06320.1 - 0.00055 19.8 0.0 0.0088 15.9 0.0 2.3 2 1 0 2 2 2 1 U-box domain DUF3546 PF12066.3 EEA06321.1 - 1.5e-20 73.2 2.4 1.5e-20 73.2 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EEA06321.1 - 2.1e-07 31.3 0.8 4.4e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Arsenite-resistance protein 2 PI3_PI4_kinase PF00454.22 EEA06322.1 - 4.8e-32 111.3 2.2 3.5e-31 108.4 0.2 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEA06322.1 - 4.5e-20 71.5 2.6 1.3e-19 70.0 1.8 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Prenyltrans PF00432.16 EEA06323.1 - 2.8e-50 167.5 12.5 1.1e-11 44.0 0.3 6.1 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA06323.1 - 2.7e-26 92.1 0.0 1.5e-15 57.5 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA06323.1 - 3.5e-05 23.7 0.0 0.0011 18.9 0.0 2.8 2 1 1 3 3 3 1 Prenyltransferase-like A2M_comp PF07678.9 EEA06323.1 - 0.042 13.0 0.0 4.7 6.3 0.0 2.8 2 1 1 3 3 3 0 A-macroglobulin complement component FAT PF02259.18 EEA06324.1 - 2.7e-14 52.9 4.4 7.5e-10 38.3 0.1 3.4 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.22 EEA06324.1 - 9.4e-11 41.6 0.1 5.7e-10 39.0 0.1 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase zf-CCCH PF00642.19 EEA06325.1 - 4.5e-06 26.2 18.7 0.00048 19.7 1.9 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA06325.1 - 0.033 14.1 5.5 0.033 14.1 3.8 3.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type DUF948 PF06103.6 EEA06326.1 - 2.5 8.0 5.7 6.6 6.6 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-primase PF09329.6 EEA06327.1 - 5.1e-13 48.4 0.2 1.7e-12 46.7 0.1 2.0 1 0 0 1 1 1 1 Primase zinc finger Cys_rich_KTR PF14205.1 EEA06327.1 - 0.015 14.7 1.5 0.041 13.3 0.4 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR RRM_1 PF00076.17 EEA06328.1 - 1.3e-13 50.3 0.0 1.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06328.1 - 3.9e-11 42.7 0.0 6.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06328.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA06330.1 - 1.1e-12 47.3 1.4 0.0068 16.0 0.0 5.6 3 3 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06330.1 - 9.5e-12 44.7 0.1 6.3e-06 26.0 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06330.1 - 0.012 15.4 0.7 8.2 6.3 0.0 3.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1_C PF08438.5 EEA06331.1 - 2.3e-28 98.5 0.7 3.8e-28 97.8 0.5 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EEA06331.1 - 3.8e-17 62.2 0.0 1.1e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA06331.1 - 4.5e-10 39.0 1.3 7.7e-08 31.7 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EEA06331.1 - 0.00099 18.7 1.1 0.22 11.0 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEA06331.1 - 0.0075 15.7 0.5 0.13 11.6 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TGS PF02824.16 EEA06331.1 - 0.0088 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain DUF281 PF03436.8 EEA06331.1 - 0.062 13.3 0.1 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) TSP_1 PF00090.14 EEA06332.1 - 0.00048 20.1 9.4 0.00048 20.1 6.5 5.0 4 1 0 4 4 4 3 Thrombospondin type 1 domain SRPRB PF09439.5 EEA06333.1 - 3.9e-24 84.8 1.0 8.7e-24 83.7 0.7 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEA06333.1 - 9.8e-15 54.2 0.1 4.4e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA06333.1 - 1.1e-06 28.5 0.1 2.1e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA06333.1 - 2.9e-06 27.7 0.4 1.1e-05 25.9 0.0 2.2 2 1 0 2 2 1 1 Miro-like protein Ras PF00071.17 EEA06333.1 - 1.1e-05 24.9 0.0 2.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEA06333.1 - 2.2e-05 23.6 0.4 3.7e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SE PF00437.15 EEA06333.1 - 0.00029 19.8 0.0 0.00042 19.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EEA06333.1 - 0.00036 19.7 0.1 0.0015 17.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA06333.1 - 0.0006 19.9 0.0 0.001 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 EEA06333.1 - 0.00085 18.1 0.3 0.0073 15.0 0.1 2.0 2 0 0 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 EEA06333.1 - 0.00091 19.5 0.1 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.9 EEA06333.1 - 0.0011 18.0 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 EEA06333.1 - 0.0023 18.7 0.0 0.0035 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EEA06333.1 - 0.0023 17.4 0.2 0.0057 16.1 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EEA06333.1 - 0.0052 16.6 0.7 0.012 15.4 0.1 1.8 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EEA06333.1 - 0.0073 15.8 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EEA06333.1 - 0.02 14.4 0.2 0.36 10.3 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EEA06333.1 - 0.024 14.3 0.8 0.044 13.4 0.6 1.8 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EEA06333.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EEA06333.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA06333.1 - 0.04 14.2 1.4 0.18 12.0 0.6 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEA06333.1 - 0.044 13.9 0.7 0.26 11.4 0.2 2.4 1 1 1 2 2 2 0 RNA helicase AAA PF00004.24 EEA06333.1 - 0.062 13.5 0.1 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA06333.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEA06333.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EEA06333.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EEA06333.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEA06333.1 - 0.19 12.0 8.0 0.66 10.2 5.5 1.8 1 1 0 1 1 1 0 AAA domain Imm48 PF15587.1 EEA06334.1 - 0.005 16.2 0.1 0.013 14.8 0.1 1.7 1 0 0 1 1 1 1 Immunity protein 48 HHH_2 PF12826.2 EEA06334.1 - 0.066 13.1 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF1119 PF06550.6 EEA06334.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) TPR_1 PF00515.23 EEA06335.1 - 2.4e-07 30.0 0.1 9.8e-07 28.1 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06335.1 - 1.9e-06 27.3 0.2 5.1e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06335.1 - 0.00018 21.0 0.2 0.00039 20.0 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_6 PF13174.1 EEA06335.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06335.1 - 0.017 15.0 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA06335.1 - 0.025 15.2 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06335.1 - 0.092 13.4 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EEA06336.1 - 2.7e-12 47.0 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA06336.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA06336.1 - 4.7e-06 26.3 0.1 0.0022 17.5 0.0 3.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA06336.1 - 0.00024 20.8 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase DUF2305 PF10230.4 EEA06336.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EEA06336.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 EEA06336.1 - 0.072 11.5 0.0 0.36 9.2 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Apc4 PF12896.2 EEA06336.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 CS PF04969.11 EEA06337.1 - 1.2e-09 38.5 0.1 1.7e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 CS domain Cucumo_coat PF00760.13 EEA06337.1 - 0.19 10.6 0.7 0.31 9.9 0.5 1.3 1 0 0 1 1 1 0 Cucumovirus coat protein Fork_head_N PF08430.7 EEA06337.1 - 0.25 11.7 2.4 0.36 11.2 1.7 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Med3 PF11593.3 EEA06337.1 - 2.2 7.4 3.9 3.3 6.8 2.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DOT1 PF08123.8 EEA06339.1 - 3.2e-05 23.3 0.0 3.2e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 Histone methylation protein DOT1 Wzz PF02706.10 EEA06339.1 - 0.043 13.6 3.9 0.11 12.3 2.7 1.7 1 0 0 1 1 1 0 Chain length determinant protein GpcrRhopsn4 PF10192.4 EEA06340.1 - 1.6e-07 30.8 33.8 1.6e-07 30.8 23.4 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF3855 PF12967.2 EEA06341.1 - 0.081 12.4 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) Prp19_bind PF06991.6 EEA06342.1 - 3.8e-31 108.3 25.1 4e-30 105.0 17.4 1.9 1 1 0 1 1 1 1 Splicing factor, Prp19-binding domain MIF4G PF02854.14 EEA06343.1 - 9.8e-30 103.5 4.9 9.8e-30 103.5 3.4 3.4 3 0 0 3 3 3 1 MIF4G domain XPG_I PF00867.13 EEA06344.1 - 7.4e-25 86.8 0.2 2.4e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EEA06344.1 - 5.9e-20 71.4 0.0 5.3e-19 68.3 0.0 2.5 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I_2 PF12813.2 EEA06344.1 - 0.00015 21.3 0.2 0.00041 19.9 0.1 1.7 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EEA06344.1 - 0.039 14.1 1.1 0.17 12.1 0.0 2.5 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Apyrase PF06079.6 EEA06345.1 - 3.4e-100 334.9 0.1 3.9e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Apyrase DUF572 PF04502.8 EEA06347.1 - 2.2e-56 191.4 8.9 2.8e-56 191.1 6.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 EEA06347.1 - 0.013 15.1 1.1 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Gag_spuma PF03276.9 EEA06347.1 - 0.2 9.9 0.3 0.28 9.4 0.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF445 PF04286.7 EEA06347.1 - 0.46 9.9 5.7 0.62 9.5 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NuA4 PF09340.5 EEA06348.1 - 8.7e-23 79.7 0.3 1.9e-22 78.6 0.2 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 SLBP_RNA_bind PF15247.1 EEA06349.1 - 5.7e-17 61.2 2.2 5.7e-17 61.2 1.6 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain BHD_1 PF10403.4 EEA06350.1 - 2.1e-13 49.5 0.1 6.1e-13 48.0 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 EEA06350.1 - 1.8e-09 37.1 1.3 0.00022 20.6 0.2 2.8 2 0 0 2 2 2 2 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEA06350.1 - 8.4e-09 35.0 0.0 4.5e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EEA06350.1 - 4.4e-07 30.1 0.3 1.9e-06 28.0 0.2 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Radical_SAM PF04055.16 EEA06351.1 - 6.9e-19 68.6 0.0 1.2e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EEA06351.1 - 6.5e-18 64.3 0.4 1.9e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EEA06351.1 - 0.0099 15.6 0.0 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 TRAM domain PKD_channel PF08016.7 EEA06352.1 - 0.013 13.9 21.0 0.022 13.2 14.5 1.3 1 0 0 1 1 1 0 Polycystin cation channel DUF3273 PF11677.3 EEA06353.1 - 7.3e-70 235.2 12.6 8.5e-70 235.0 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF106 PF01956.11 EEA06354.1 - 1.7e-16 60.1 2.4 2.4e-16 59.7 1.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF2512 PF10710.4 EEA06354.1 - 0.021 14.3 1.9 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) DUF3112 PF11309.3 EEA06354.1 - 0.11 12.2 0.9 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF912 PF06024.7 EEA06354.1 - 0.16 12.0 4.4 0.11 12.4 1.8 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TetR PF13972.1 EEA06355.1 - 0.068 12.6 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor SET PF00856.23 EEA06356.1 - 1.2e-11 45.1 5.5 2.4e-11 44.1 0.1 3.2 3 1 0 3 3 3 1 SET domain CRAL_TRIO PF00650.15 EEA06357.1 - 4.4e-34 117.2 0.1 6.8e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA06357.1 - 1.9e-09 37.4 0.1 8.3e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA06357.1 - 0.0034 17.2 2.8 0.0045 16.8 0.5 2.3 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Rep_Org_C PF06926.6 EEA06357.1 - 0.058 13.4 0.5 13 5.9 0.0 2.9 2 1 1 3 3 3 0 Putative replisome organiser protein C-terminus PS_pyruv_trans PF04230.8 EEA06358.1 - 2.7e-19 69.9 1.8 7.2e-19 68.5 1.1 1.9 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Fringe PF02434.11 EEA06358.1 - 2e-14 53.4 0.1 4.7e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EEA06358.1 - 2.6e-10 40.2 0.0 6.6e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Galactosyltransferase DUF2475 PF10629.4 EEA06358.1 - 0.015 15.4 0.1 0.43 10.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) Myb_DNA-bind_4 PF13837.1 EEA06360.1 - 0.68 10.1 5.8 1.4 9.0 3.9 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain E2F_TDP PF02319.15 EEA06361.1 - 1.1e-17 63.3 0.0 2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain BPL_LplA_LipB PF03099.14 EEA06362.1 - 7.5e-22 77.6 0.8 1.3e-21 76.9 0.2 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EEA06362.1 - 1e-17 63.5 2.5 4.3e-17 61.5 0.1 2.9 3 1 1 4 4 4 1 Bacterial lipoate protein ligase C-terminus Pkinase PF00069.20 EEA06363.1 - 3e-63 213.3 0.0 5.2e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06363.1 - 2.6e-29 102.1 0.0 6.8e-29 100.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Prok-E2_C PF14459.1 EEA06363.1 - 0.014 15.4 0.1 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family C Bul1_C PF04426.7 EEA06363.1 - 0.11 11.7 1.2 0.2 10.8 0.8 1.4 1 0 0 1 1 1 0 Bul1 C terminus OB_NTP_bind PF07717.11 EEA06364.1 - 9.8e-32 109.1 0.0 2.1e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA06364.1 - 7.9e-29 99.6 0.0 4.9e-28 97.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA06364.1 - 2.1e-09 37.0 0.0 5.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEA06364.1 - 1.6e-06 28.2 0.0 4.9e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEA06364.1 - 2.4e-06 27.1 0.1 6.2e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EEA06364.1 - 0.00021 20.2 0.0 0.00059 18.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EEA06364.1 - 0.0025 18.1 0.9 0.42 10.9 0.3 3.4 2 1 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 EEA06364.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EEA06364.1 - 0.012 15.4 0.1 7 6.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EEA06364.1 - 0.029 13.6 0.1 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 EEA06364.1 - 0.038 13.8 0.1 1 9.2 0.1 2.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EEA06364.1 - 0.045 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Miro PF08477.8 EEA06364.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SRP54 PF00448.17 EEA06364.1 - 0.071 12.5 0.1 0.27 10.6 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EEA06364.1 - 0.14 11.7 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA06364.1 - 0.27 10.8 0.1 0.61 9.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain TBPIP PF07106.8 EEA06365.1 - 0.0034 16.9 4.1 0.0058 16.2 2.8 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FTA4 PF13093.1 EEA06365.1 - 0.0063 15.9 0.4 0.0089 15.4 0.3 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 bZIP_1 PF00170.16 EEA06365.1 - 0.008 16.1 1.1 0.008 16.1 0.7 2.2 3 0 0 3 3 3 1 bZIP transcription factor Med21 PF11221.3 EEA06365.1 - 0.014 15.3 3.7 0.57 10.1 1.3 2.3 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Ded_cyto PF06920.8 EEA06365.1 - 0.022 14.0 0.2 0.12 11.6 0.4 1.8 2 0 0 2 2 2 0 Dedicator of cytokinesis C9orf72-like PF15019.1 EEA06365.1 - 0.097 11.8 0.5 0.14 11.3 0.4 1.4 1 1 0 1 1 1 0 C9orf72-like protein family Ribosom_S12_S23 PF00164.20 EEA06366.1 - 5.5e-40 135.5 0.6 6.4e-40 135.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.5 EEA06366.1 - 0.007 15.9 0.0 0.0078 15.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Hist_deacetyl PF00850.14 EEA06368.1 - 2.9e-74 250.1 0.1 3.8e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Hus1 PF04005.7 EEA06369.1 - 6.1e-17 61.5 2.7 1.1e-16 60.5 1.9 1.5 1 1 0 1 1 1 1 Hus1-like protein RasGEF_N PF00618.15 EEA06369.1 - 0.13 12.3 1.3 0.5 10.5 0.4 2.2 1 1 1 2 2 2 0 RasGEF N-terminal motif CITED PF04487.7 EEA06370.1 - 0.57 10.3 5.1 0.72 10.0 3.5 1.2 1 0 0 1 1 1 0 CITED FimP PF09766.4 EEA06371.1 - 7.1e-11 41.7 13.0 6.5e-05 22.1 7.8 2.6 2 1 0 2 2 2 2 Fms-interacting protein ISG65-75 PF11727.3 EEA06371.1 - 0.016 14.2 0.8 0.024 13.6 0.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Prefoldin_2 PF01920.15 EEA06371.1 - 0.13 12.0 8.7 0.091 12.5 2.1 3.1 2 1 1 3 3 3 0 Prefoldin subunit STAT_alpha PF01017.15 EEA06371.1 - 0.47 10.1 12.3 0.14 11.8 3.5 2.4 1 1 1 2 2 2 0 STAT protein, all-alpha domain GrpE PF01025.14 EEA06371.1 - 0.74 9.3 6.5 2.8 7.4 1.3 2.3 1 1 1 2 2 2 0 GrpE Seryl_tRNA_N PF02403.17 EEA06371.1 - 1.5 8.8 12.6 0.27 11.2 3.4 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain VID27 PF08553.5 EEA06372.1 - 0.1 10.8 3.1 0.13 10.4 2.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-CCCH PF00642.19 EEA06374.1 - 1.3e-12 47.0 12.5 1e-06 28.2 0.1 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA06374.1 - 0.00061 19.6 1.0 1.2 9.2 0.1 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type HAD_2 PF13419.1 EEA06377.1 - 0.071 13.3 0.0 2.5 8.3 0.0 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PAN_4 PF14295.1 EEA06378.1 - 5.5e-05 22.7 18.9 0.00049 19.7 0.0 3.5 4 1 0 4 4 4 2 PAN domain PAN_1 PF00024.21 EEA06378.1 - 0.00029 20.5 11.1 0.0031 17.2 1.8 3.0 2 1 0 2 2 2 2 PAN domain TSP_1 PF00090.14 EEA06378.1 - 0.068 13.3 0.1 0.068 13.3 0.1 5.0 3 1 1 4 4 4 0 Thrombospondin type 1 domain zf-RING_2 PF13639.1 EEA06379.1 - 2e-10 40.3 13.5 2e-10 40.3 9.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA06379.1 - 1.4e-06 28.2 11.0 1.4e-06 28.2 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA06379.1 - 4.3e-06 26.7 10.2 2.2e-05 24.4 7.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA06379.1 - 6e-06 25.8 9.0 6e-06 25.8 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA06379.1 - 1.4e-05 24.6 9.1 1.4e-05 24.6 6.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA06379.1 - 0.0027 17.4 10.6 0.0027 17.4 7.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Sarcoglycan_2 PF05510.8 EEA06379.1 - 0.024 12.9 1.2 0.046 12.0 0.1 1.7 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Rtf2 PF04641.7 EEA06379.1 - 0.044 12.9 0.9 0.06 12.5 0.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EEA06379.1 - 0.055 13.2 4.1 0.16 11.7 2.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger HemY_N PF07219.8 EEA06379.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus zf-Apc11 PF12861.2 EEA06379.1 - 0.083 12.7 3.3 0.18 11.6 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Adeno_E3_CR2 PF02439.10 EEA06379.1 - 0.11 12.1 1.2 0.3 10.6 0.8 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-C3HC4_4 PF15227.1 EEA06379.1 - 1.1 9.1 11.6 7 6.6 8.0 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CD20 PF04103.10 EEA06379.1 - 3 7.7 8.3 0.17 11.7 1.0 2.2 1 1 0 2 2 2 0 CD20-like family DUF2967 PF11179.3 EEA06380.1 - 0.033 13.6 6.2 0.054 12.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Acyltransferase PF01553.16 EEA06381.1 - 3.2e-15 55.7 0.0 4.1e-14 52.1 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Clp1 PF06807.9 EEA06384.1 - 0.00026 20.8 0.2 0.022 14.4 0.1 2.2 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEA06384.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA06384.1 - 0.0039 16.6 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EEA06384.1 - 0.013 15.4 0.6 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA06384.1 - 0.014 15.0 0.2 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 EEA06384.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAP_beta PF05753.9 EEA06385.1 - 0.0076 15.4 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Methyltransf_PK PF05891.7 EEA06386.1 - 8.8e-47 159.2 0.1 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 EEA06386.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_11 PF08241.7 EEA06386.1 - 0.0005 20.5 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA06386.1 - 0.0028 18.0 0.1 0.0095 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA06386.1 - 0.019 14.5 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEA06386.1 - 0.02 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TP_methylase PF00590.15 EEA06387.1 - 1.1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DnaJ PF00226.26 EEA06388.1 - 4.2e-22 77.6 0.7 4.2e-22 77.6 0.5 2.4 2 0 0 2 2 2 1 DnaJ domain DASH_Ask1 PF08655.5 EEA06388.1 - 0.39 10.5 6.1 2.2 8.1 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Ask1 SLX9 PF15341.1 EEA06388.1 - 0.44 10.9 11.0 0.17 12.3 5.3 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 HECT PF00632.20 EEA06389.1 - 1.5e-13 50.5 1.4 1.5e-13 50.5 0.9 2.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF948 PF06103.6 EEA06392.1 - 0.0098 15.7 1.0 0.0098 15.7 0.7 2.4 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF4319 PF14203.1 EEA06392.1 - 0.033 13.7 1.4 4.1 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) AP2 PF00847.15 EEA06393.1 - 1.1e-11 44.7 4.4 5.4e-06 26.4 0.9 2.4 2 0 0 2 2 2 2 AP2 domain Flavodoxin_2 PF02525.12 EEA06395.1 - 1.4e-12 47.5 0.0 1.7e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold DnaJ PF00226.26 EEA06397.1 - 1.3e-17 63.3 0.1 3.4e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Syntaxin-6_N PF09177.6 EEA06402.1 - 0.16 12.3 6.9 0.29 11.5 0.3 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.6 EEA06402.1 - 0.21 11.4 2.1 0.38 10.6 0.8 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EEA06402.1 - 1.8 8.4 17.3 7.7 6.3 5.7 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_ab PF00006.20 EEA06403.1 - 4e-65 219.3 0.0 6.3e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA06403.1 - 5.3e-23 81.6 0.7 1e-22 80.7 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA06403.1 - 1.3e-21 76.5 0.2 2.3e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EEA06403.1 - 0.003 17.7 0.3 0.3 11.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEA06403.1 - 0.0045 16.6 0.3 2.5 7.8 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EEA06403.1 - 0.0084 15.2 1.3 0.012 14.7 0.2 1.7 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 EEA06403.1 - 0.0097 15.6 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EEA06403.1 - 0.051 12.9 0.4 0.3 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain RnfC_N PF13375.1 EEA06403.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF258 PF03193.11 EEA06403.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EEA06403.1 - 0.08 12.5 0.3 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EEA06403.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 EEA06403.1 - 0.2 11.6 0.5 0.66 9.9 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain NB-ARC PF00931.17 EEA06403.1 - 0.24 10.2 1.2 0.24 10.2 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_DE_N PF02823.11 EEA06404.1 - 9.4e-13 47.7 0.0 1.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TypeIII_RM_meth PF12564.3 EEA06404.1 - 0.063 13.2 0.9 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit AAA PF00004.24 EEA06405.1 - 5.6e-42 143.0 0.0 1.4e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA06405.1 - 7.4e-06 25.7 1.6 2.5e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEA06405.1 - 6.3e-05 22.1 0.0 0.00021 20.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA06405.1 - 6.5e-05 22.9 0.3 0.002 18.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain TMF_TATA_bd PF12325.3 EEA06405.1 - 7.6e-05 22.4 2.7 7.6e-05 22.4 1.9 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding AAA_22 PF13401.1 EEA06405.1 - 0.00011 22.3 0.4 0.014 15.5 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEA06405.1 - 0.00055 19.8 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEA06405.1 - 0.0027 17.6 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA06405.1 - 0.0044 16.2 0.1 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEA06405.1 - 0.0048 16.3 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Striatin PF08232.7 EEA06405.1 - 0.0052 17.0 0.6 0.01 16.1 0.4 1.5 1 0 0 1 1 1 1 Striatin family AAA_19 PF13245.1 EEA06405.1 - 0.0057 16.3 0.3 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF1640 PF07798.6 EEA06405.1 - 0.0068 16.4 1.3 0.013 15.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PhoH PF02562.11 EEA06405.1 - 0.0071 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF815 PF05673.8 EEA06405.1 - 0.0072 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Leu_zip PF15294.1 EEA06405.1 - 0.021 13.9 2.8 0.035 13.2 1.9 1.2 1 0 0 1 1 1 0 Leucine zipper AAA_17 PF13207.1 EEA06405.1 - 0.023 15.5 0.1 0.075 13.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 EEA06405.1 - 0.025 13.7 0.5 0.16 11.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EEA06405.1 - 0.031 13.3 0.6 0.066 12.2 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin DUF1192 PF06698.6 EEA06405.1 - 0.039 13.7 0.3 0.097 12.4 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_25 PF13481.1 EEA06405.1 - 0.052 12.9 2.2 0.29 10.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 EEA06405.1 - 0.065 12.8 2.2 0.072 12.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EEA06405.1 - 0.07 11.8 0.2 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activat PF00158.21 EEA06405.1 - 0.073 12.5 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EEA06405.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA06405.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF904 PF06005.7 EEA06405.1 - 0.21 11.8 9.7 0.23 11.7 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) PI3_PI4_kinase PF00454.22 EEA06406.1 - 2.3e-26 92.7 0.0 4.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CTDII PF01556.13 EEA06408.1 - 1.1e-24 86.0 6.9 2e-16 59.6 0.6 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EEA06408.1 - 1.4e-22 79.2 0.2 2.4e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEA06408.1 - 6.2e-12 45.4 16.5 1.1e-11 44.6 11.4 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF1217 PF06748.7 EEA06408.1 - 0.013 15.6 0.0 0.087 12.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1217) DUF2207 PF09972.4 EEA06410.1 - 0.025 13.1 7.1 0.032 12.8 4.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 EEA06411.1 - 1.8e-74 250.2 0.0 4.6e-74 248.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06411.1 - 1.5e-30 106.1 0.0 3.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EEA06411.1 - 3.9e-28 94.5 2.1 1e-06 27.6 0.3 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA06411.1 - 5.7e-24 84.0 3.1 6.2e-12 45.4 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA06411.1 - 7.1e-23 78.8 2.1 1.1e-05 24.5 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEA06411.1 - 1.7e-20 71.0 3.9 0.00038 20.0 0.0 5.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EEA06411.1 - 2e-20 72.1 8.8 9.8e-11 41.1 0.4 4.7 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEA06411.1 - 4.8e-07 29.8 0.5 0.04 13.9 0.1 2.9 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EEA06411.1 - 0.00047 20.0 0.3 0.0072 16.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain APH PF01636.18 EEA06411.1 - 0.0025 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA06411.1 - 0.094 11.7 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 EEA06411.1 - 0.16 11.6 1.0 5.8 6.7 0.2 2.8 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DDHD PF02862.12 EEA06413.1 - 2.8e-38 131.9 1.5 6e-38 130.8 0.0 2.0 2 0 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 EEA06413.1 - 0.00015 21.7 0.0 0.00029 20.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEA06413.1 - 0.00087 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EEA06413.1 - 0.0019 17.9 0.0 0.0078 15.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA06413.1 - 0.005 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EEA06413.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EEA06413.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 EEA06413.1 - 0.017 14.4 0.0 5.2 6.3 0.0 2.7 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EEA06413.1 - 0.028 13.9 0.1 0.13 11.8 0.0 2.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EEA06413.1 - 0.22 11.0 0.0 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Guanylate_cyc PF00211.15 EEA06414.1 - 6e-17 61.5 0.1 2.8e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain COG2 PF06148.6 EEA06415.1 - 3.3e-06 26.9 1.1 1.4e-05 24.9 0.6 2.2 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EEA06415.1 - 0.26 11.3 8.0 0.036 14.1 1.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) MCM PF00493.18 EEA06417.1 - 1.4e-127 425.0 0.0 1.2e-126 422.0 0.0 2.0 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA06417.1 - 1.4e-15 57.8 0.8 6.8e-15 55.6 0.2 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA06417.1 - 1.6e-05 24.1 0.0 0.00024 20.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA06417.1 - 9.6e-05 22.1 0.0 0.00052 19.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA06417.1 - 0.0077 15.8 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EEA06417.1 - 0.085 12.3 0.1 16 4.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase EF-hand_4 PF12763.2 EEA06418.1 - 1.1e-19 70.0 1.9 7.9e-11 41.6 0.3 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EEA06418.1 - 6.3e-13 48.6 3.0 3.2e-08 33.5 0.3 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA06418.1 - 3.5e-10 38.4 7.8 0.0046 16.1 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEA06418.1 - 1.3e-05 24.6 6.8 0.094 12.6 0.2 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EEA06418.1 - 8.9e-05 21.6 3.1 0.23 10.8 0.0 3.1 2 0 0 2 2 2 2 EF hand DUF869 PF05911.6 EEA06418.1 - 0.081 11.1 22.3 0.0098 14.1 11.4 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) EF-hand_8 PF13833.1 EEA06418.1 - 0.11 12.0 5.9 12 5.5 0.0 4.7 5 0 0 5 5 5 0 EF-hand domain pair DENN PF02141.16 EEA06421.1 - 3.2e-22 79.1 9.4 1.1e-21 77.4 6.5 2.0 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EEA06421.1 - 0.00019 21.3 0.1 0.00063 19.6 0.1 2.0 1 0 0 1 1 1 1 uDENN domain PTS_2-RNA PF01885.11 EEA06423.1 - 4.1e-37 127.2 0.0 5.2e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Steroid_dh PF02544.11 EEA06424.1 - 1.5e-33 115.6 9.2 1.5e-33 115.6 6.3 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_15 PF09445.5 EEA06426.1 - 5e-27 94.4 1.7 4.9e-16 58.7 0.2 3.1 2 1 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EEA06426.1 - 3.4e-07 30.3 0.0 4e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA06426.1 - 0.0014 19.1 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEA06426.1 - 0.017 14.4 0.1 0.12 11.7 0.0 2.4 4 0 0 4 4 4 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EEA06426.1 - 0.077 13.3 0.0 0.22 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-ZPR1 PF03367.8 EEA06427.1 - 5.9e-91 301.8 0.6 3.1e-48 162.9 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 EEA06427.1 - 0.038 13.9 5.9 7.1 6.6 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain IL13 PF03487.8 EEA06427.1 - 0.042 13.5 1.5 0.096 12.4 1.1 1.6 1 0 0 1 1 1 0 Interleukin-13 zinc_ribbon_2 PF13240.1 EEA06427.1 - 0.12 11.9 13.4 5 6.7 1.0 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Mss51 PF13824.1 EEA06427.1 - 0.13 12.1 5.7 4.6 7.1 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HypA PF01155.14 EEA06427.1 - 0.14 11.8 8.2 1 9.0 0.6 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 EEA06427.1 - 0.38 11.1 2.4 91 3.6 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 EEA06427.1 - 1.3 8.3 14.4 5.2 6.4 4.7 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Rhomboid PF01694.17 EEA06428.1 - 2.8e-17 63.0 3.8 4.5e-17 62.4 2.6 1.3 1 0 0 1 1 1 1 Rhomboid family Paf67 PF10255.4 EEA06429.1 - 1.7e-116 389.4 6.1 2.3e-116 389.0 4.2 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EEA06429.1 - 0.0013 18.4 0.1 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06429.1 - 0.02 14.7 0.1 0.093 12.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06429.1 - 0.055 13.1 0.1 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EEA06430.1 - 1.6e-25 87.8 48.5 2.6e-05 24.3 1.6 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA06430.1 - 4.6e-24 82.9 46.0 0.00026 21.0 0.7 7.7 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA06430.1 - 7.5e-14 51.2 52.6 6.3e-06 26.2 0.6 9.1 9 1 0 9 9 9 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEA06430.1 - 3.8e-08 32.9 18.1 0.062 13.2 0.1 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.2 EEA06430.1 - 0.0012 18.9 24.3 0.28 11.4 0.1 7.5 7 1 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA06430.1 - 0.52 10.5 26.3 2.8 8.2 0.2 7.8 7 2 1 8 8 8 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 EEA06430.1 - 0.75 8.2 26.8 2.8 6.3 0.0 5.5 1 1 4 6 6 6 0 Protein of unknown function (DUF629) zf-met2 PF12907.2 EEA06430.1 - 1.3 9.0 0.0 1.3 9.0 0.0 5.6 6 0 0 6 6 6 0 Zinc-binding DUF2321 PF10083.4 EEA06430.1 - 8.2 5.9 11.2 8.6 5.8 0.1 3.2 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) SNARE PF05739.14 EEA06431.1 - 1.1e-14 53.7 0.4 1.1e-14 53.7 0.3 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEA06431.1 - 2.3e-06 27.6 11.3 2.3e-06 27.6 7.9 2.5 2 1 1 3 3 3 1 Syntaxin IF-2 PF11987.3 EEA06431.1 - 0.0017 18.2 0.6 0.0035 17.1 0.4 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 Med10 PF09748.4 EEA06431.1 - 0.0028 17.4 6.6 0.03 14.1 1.3 2.2 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex TroA PF01297.12 EEA06431.1 - 0.029 13.6 0.2 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family DUF3348 PF11828.3 EEA06431.1 - 0.045 13.1 3.0 0.075 12.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF3574 PF12098.3 EEA06431.1 - 0.06 12.9 2.3 0.13 11.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) DUF357 PF04010.8 EEA06431.1 - 0.15 11.7 0.8 0.67 9.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) Cep57_CLD_2 PF14197.1 EEA06431.1 - 0.22 11.4 9.1 7.3 6.6 0.9 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 EEA06431.1 - 0.65 9.1 3.4 0.82 8.7 0.1 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Sec20 PF03908.8 EEA06431.1 - 1.1 8.9 9.1 6.5 6.5 1.5 2.9 2 2 1 3 3 3 0 Sec20 DUF3452 PF11934.3 EEA06431.1 - 1.1 8.5 9.2 0.8 9.0 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Syntaxin-6_N PF09177.6 EEA06431.1 - 1.2 9.6 15.4 2.3 8.6 5.0 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Allexi_40kDa PF05549.6 EEA06431.1 - 2.2 7.4 13.7 1.5 8.0 3.8 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3899 PF13038.1 EEA06431.1 - 2.5 8.3 4.3 0.78 9.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) HisKA_3 PF07730.8 EEA06431.1 - 2.9 8.2 7.3 2.5 8.4 0.5 3.1 3 1 0 3 3 3 0 Histidine kinase DUF349 PF03993.7 EEA06431.1 - 3.4 7.9 7.3 7.9 6.7 0.3 3.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Mit_KHE1 PF10173.4 EEA06431.1 - 6.1 6.6 14.3 65 3.2 9.9 2.1 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Pepsin-I3 PF06394.8 EEA06431.1 - 6.4 6.5 6.4 2.2 7.9 0.3 2.6 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain ThiF PF00899.16 EEA06433.1 - 7.2e-37 126.2 0.0 1.3e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EEA06433.1 - 1.3e-15 56.6 0.3 2.8e-14 52.4 0.2 2.5 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EEA06433.1 - 2.2e-08 34.4 1.1 9.8e-08 32.3 0.1 2.6 3 1 0 3 3 3 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.9 EEA06433.1 - 0.013 14.9 0.3 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EEA06433.1 - 0.041 12.9 0.6 0.059 12.4 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EEA06433.1 - 0.064 12.6 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EEA06433.1 - 0.066 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EEA06433.1 - 0.095 11.8 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PLDc_2 PF13091.1 EEA06434.1 - 2.7e-07 30.3 10.1 0.001 18.8 3.5 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEA06434.1 - 0.0072 16.0 3.1 0.018 14.8 0.0 3.3 4 0 0 4 4 4 1 Phospholipase D Active site motif MCM PF00493.18 EEA06435.1 - 1.5e-135 451.2 0.5 3.6e-135 450.0 0.3 1.6 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EEA06435.1 - 2.9e-25 89.0 21.1 2.9e-25 89.0 14.6 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EEA06435.1 - 4.8e-19 69.0 2.5 5.9e-19 68.7 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA06435.1 - 5e-07 29.1 0.0 3.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA06435.1 - 0.00011 21.7 0.0 0.00041 19.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA06435.1 - 0.00023 20.8 0.0 0.00079 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EEA06435.1 - 0.017 14.5 0.0 0.2 11.0 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain MBOAT PF03062.14 EEA06436.1 - 1.8e-20 73.3 33.2 8.4e-20 71.1 23.0 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EEA06436.1 - 0.00027 20.9 3.4 0.00093 19.2 2.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Yos1 PF08571.5 EEA06436.1 - 0.1 12.6 2.9 0.27 11.3 2.0 1.7 1 0 0 1 1 1 0 Yos1-like Ribosomal_S25 PF03297.10 EEA06438.1 - 4.9e-37 126.1 2.5 5.4e-37 126.0 1.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Trypan_glycop_C PF10659.4 EEA06438.1 - 0.059 13.6 0.3 0.082 13.1 0.2 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Pkinase PF00069.20 EEA06439.1 - 3.3e-75 252.5 0.0 6.1e-75 251.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06439.1 - 2.3e-35 121.9 0.0 3.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EEA06439.1 - 5.3e-27 93.7 0.4 3.9e-12 46.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA06439.1 - 1.2e-26 89.9 5.5 2.6e-08 32.5 1.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 EEA06439.1 - 9.3e-20 69.0 8.3 5.8e-05 22.2 1.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEA06439.1 - 2.3e-19 67.4 3.4 0.00025 20.6 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EEA06439.1 - 3.7e-13 48.8 6.9 6.9e-06 25.5 0.3 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EEA06439.1 - 0.00014 21.5 0.2 0.51 10.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 EEA06439.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA06439.1 - 0.006 16.3 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA06439.1 - 0.0081 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.1 EEA06439.1 - 0.043 13.7 0.0 0.26 11.2 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain Cyt-b5 PF00173.23 EEA06441.1 - 1.7e-23 82.2 0.0 2.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNase_H_2 PF13482.1 EEA06441.1 - 0.06 13.1 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 RNase_H superfamily Mito_carr PF00153.22 EEA06442.1 - 3.1e-67 222.3 0.0 1.3e-21 76.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.22 EEA06443.1 - 4.3e-08 33.4 4.5 6.1e-08 32.9 0.3 2.7 2 0 0 2 2 2 1 PCI domain DEAD PF00270.24 EEA06444.1 - 1.2e-42 145.3 0.0 2.7e-42 144.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06444.1 - 3e-27 94.2 0.0 7.5e-27 93.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA06444.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA06444.1 - 0.025 13.6 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.17 EEA06445.1 - 2.4e-13 49.5 0.0 2.5e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06445.1 - 8.1e-09 35.3 0.0 8e-06 25.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06445.1 - 8.4e-06 25.5 0.0 0.0005 19.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGT PF01702.13 EEA06446.1 - 6.8e-39 133.5 0.0 1.1e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RNA_pol_Rpb5_C PF01191.14 EEA06447.1 - 4.7e-36 122.2 0.8 8.4e-36 121.4 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEA06447.1 - 9.6e-25 86.8 3.7 1.7e-24 86.0 2.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEA06447.1 - 0.017 14.8 0.2 0.033 14.0 0.2 1.6 1 1 0 1 1 1 0 Restriction endonuclease RC-P840_PscD PF10657.4 EEA06447.1 - 0.025 14.4 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD PPTA PF01239.17 EEA06450.1 - 3.1e-05 23.1 11.6 0.037 13.3 1.2 5.1 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat NAD_binding_6 PF08030.7 EEA06450.1 - 0.13 12.2 1.4 6.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Kazal_2 PF07648.10 EEA06451.1 - 8e-43 144.1 33.5 9.1e-12 44.7 3.0 5.5 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EEA06451.1 - 1.1e-39 134.1 33.7 5.3e-10 39.1 2.5 5.4 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain DUF3944 PF13099.1 EEA06451.1 - 0.087 12.3 9.3 30 4.1 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3944) Orthopox_A49R PF06489.6 EEA06452.1 - 0.012 15.5 2.1 0.056 13.4 0.7 2.3 2 0 0 2 2 2 0 Orthopoxvirus A49R protein Peptidase_M16 PF00675.15 EEA06453.1 - 6.8e-34 116.7 0.1 4.7e-33 114.0 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA06453.1 - 3.9e-22 78.8 3.7 3.6e-15 56.1 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Pkinase PF00069.20 EEA06454.1 - 5.3e-16 58.5 1.6 6.7e-16 58.2 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Cpn60_TCP1 PF00118.19 EEA06455.1 - 8.2e-126 420.4 11.8 9.4e-126 420.2 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tetraspannin PF00335.15 EEA06456.1 - 2.9e-06 26.7 2.5 4.1e-06 26.2 1.7 1.4 1 0 0 1 1 1 1 Tetraspanin family zf-C3HC4_2 PF13923.1 EEA06458.1 - 8.6e-11 41.6 10.6 8.6e-11 41.6 7.3 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA06458.1 - 8.7e-10 38.1 8.4 8.7e-10 38.1 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA06458.1 - 2.2e-09 36.7 10.1 1.1e-08 34.6 7.0 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA06458.1 - 3.4e-08 33.1 10.3 3.4e-08 33.1 7.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EEA06458.1 - 5.9e-07 29.1 11.7 5.9e-07 29.1 8.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EEA06458.1 - 2.4e-06 27.2 2.7 6.8e-06 25.7 1.9 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EEA06458.1 - 8.6e-05 22.3 7.9 0.00033 20.4 5.5 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA06458.1 - 0.0004 20.0 9.0 0.0008 19.0 5.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EEA06458.1 - 0.0015 18.5 5.8 0.0058 16.7 4.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger SAB PF04382.8 EEA06458.1 - 0.0032 17.1 0.2 0.013 15.1 0.2 2.1 1 0 0 1 1 1 1 SAB domain Prok-RING_4 PF14447.1 EEA06458.1 - 0.0076 15.7 3.5 0.0076 15.7 2.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FliD_N PF02465.13 EEA06458.1 - 0.028 14.7 1.0 0.028 14.7 0.7 4.3 4 2 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus zf-Apc11 PF12861.2 EEA06458.1 - 0.35 10.7 4.6 0.76 9.6 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Reo_sigmaC PF04582.7 EEA06458.1 - 9.1 5.3 23.2 0.15 11.2 1.4 4.3 4 1 1 5 5 5 0 Reovirus sigma C capsid protein DUF1014 PF06244.7 EEA06459.1 - 1.2e-26 93.2 2.8 1.2e-26 93.2 1.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EEA06459.1 - 0.00017 21.7 0.9 0.00017 21.7 0.6 2.7 3 1 0 3 3 3 1 HMG (high mobility group) box TEX19 PF15553.1 EEA06459.1 - 0.5 10.2 2.4 0.71 9.7 1.7 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 U79_P34 PF03064.11 EEA06459.1 - 0.7 9.3 11.5 1 8.8 8.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP_sp32 PF07222.7 EEA06459.1 - 8 5.5 15.4 6.3 5.8 9.9 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 AAA_11 PF13086.1 EEA06459.1 - 9 5.7 9.1 6 6.3 5.2 1.5 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.21 EEA06460.1 - 6.8e-47 159.2 1.3 7.7e-47 159.0 0.9 1.0 1 0 0 1 1 1 1 Proteasome subunit P5CR_dimer PF14748.1 EEA06460.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation PIG-P PF08510.7 EEA06462.1 - 6e-26 90.5 3.4 9.1e-25 86.7 2.3 2.0 1 1 0 1 1 1 1 PIG-P DUF986 PF06173.7 EEA06462.1 - 0.035 13.9 1.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF986) DUF846 PF05832.7 EEA06463.1 - 1.3e-41 141.6 18.7 1.7e-41 141.2 12.9 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4149 PF13664.1 EEA06463.1 - 1.3 9.1 10.3 3.2 7.8 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) RseC_MucC PF04246.7 EEA06463.1 - 1.5 8.3 4.9 13 5.4 0.8 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SUI1 PF01253.17 EEA06464.1 - 8.8e-29 99.1 0.2 1e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.9 EEA06464.1 - 0.037 14.2 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) EF-hand_1 PF00036.27 EEA06466.1 - 1.4e-38 127.2 11.3 5.3e-09 34.7 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA06466.1 - 1e-35 121.6 4.5 2.1e-19 69.3 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA06466.1 - 1.5e-31 107.7 12.9 3.6e-16 58.5 0.7 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEA06466.1 - 2e-28 95.6 7.3 2.4e-09 36.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA06466.1 - 3.7e-24 82.9 7.4 3.8e-06 25.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EEA06466.1 - 4.4e-12 45.7 0.1 3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA06466.1 - 2.3e-08 33.6 0.4 0.00088 18.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEA06466.1 - 1.7e-07 31.2 0.1 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EEA06466.1 - 8.1e-05 22.1 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EEA06466.1 - 0.00022 20.8 0.1 0.18 11.3 0.0 2.5 1 1 1 3 3 3 2 Caleosin related protein EFhand_Ca_insen PF08726.5 EEA06466.1 - 0.0028 17.5 1.2 0.011 15.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EEA06466.1 - 0.0069 16.1 0.2 0.85 9.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.5 EEA06466.1 - 0.025 14.3 0.1 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF1103 PF06513.6 EEA06466.1 - 0.035 13.4 0.5 0.04 13.3 0.3 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Toprim_2 PF13155.1 EEA06466.1 - 0.042 14.1 0.3 13 6.1 0.1 2.7 1 1 1 2 2 2 0 Toprim-like LNS2 PF08235.8 EEA06466.1 - 0.054 13.0 0.0 0.81 9.2 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1880 PF08976.6 EEA06466.1 - 0.071 13.2 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) RNA_pol_Rpb4 PF03874.11 EEA06466.1 - 0.076 13.0 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 Poly_export PF02563.11 EEA06466.1 - 0.081 12.7 0.0 5.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein Tenui_NCP PF04876.7 EEA06466.1 - 0.13 11.8 0.1 0.54 9.7 0.0 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein RloB PF13707.1 EEA06466.1 - 0.18 11.4 1.1 2 8.0 0.2 2.3 1 1 1 2 2 2 0 RloB-like protein MFS_1 PF07690.11 EEA06467.1 - 8.4e-19 67.4 40.1 2.6e-17 62.5 26.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA06467.1 - 0.006 15.0 35.4 0.011 14.2 4.1 4.4 3 2 1 4 4 4 3 MFS/sugar transport protein LCCL PF03815.14 EEA06468.1 - 4.9e-89 292.5 8.1 4e-23 81.2 0.3 4.8 4 0 0 4 4 4 4 LCCL domain SRCR PF00530.13 EEA06468.1 - 1.4e-29 102.2 8.9 3.7e-17 62.4 2.0 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.1 EEA06468.1 - 3.4e-20 72.8 2.1 4.7e-20 72.3 0.3 2.1 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily PLAT PF01477.18 EEA06468.1 - 6.4e-17 61.9 0.1 1.6e-11 44.5 0.0 2.8 3 0 0 3 3 3 2 PLAT/LH2 domain Rxt3 PF08642.5 EEA06468.1 - 1.6e-07 31.5 1.0 0.017 15.3 0.1 5.0 3 2 1 4 4 4 1 Histone deacetylation protein Rxt3 Pentaxin PF00354.12 EEA06468.1 - 3.8e-06 26.4 0.1 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family SRCR_2 PF15494.1 EEA06468.1 - 0.00014 22.0 2.1 0.0019 18.3 0.3 2.6 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Sialidase PF02973.11 EEA06468.1 - 0.012 14.6 0.4 0.032 13.2 0.3 1.7 1 0 0 1 1 1 0 Sialidase, N-terminal domain YecR PF13992.1 EEA06468.1 - 0.042 14.0 2.1 1.9 8.6 0.3 2.8 2 0 0 2 2 2 0 YecR-like lipoprotein Bac_surface_Ag PF01103.18 EEA06470.1 - 3.5e-20 72.7 1.1 5.3e-20 72.1 0.8 1.2 1 0 0 1 1 1 1 Surface antigen SNAP PF14938.1 EEA06471.1 - 2.6e-61 207.2 14.5 9e-59 198.9 10.1 2.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EEA06471.1 - 1.5e-08 34.4 2.9 0.0054 16.6 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06471.1 - 4.9e-07 29.3 4.1 0.0025 17.4 1.8 3.7 2 1 2 4 4 4 3 TPR repeat Sel1 PF08238.7 EEA06471.1 - 3.7e-05 24.2 3.4 1 10.0 0.1 4.4 5 0 0 5 5 5 2 Sel1 repeat TPR_2 PF07719.12 EEA06471.1 - 0.00068 19.3 13.4 3.9 7.6 0.4 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06471.1 - 0.0096 15.5 16.8 4.5 7.0 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat NSF PF02071.15 EEA06471.1 - 0.1 13.2 14.7 15 6.7 0.1 6.2 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.1 EEA06471.1 - 0.11 12.3 11.1 21 5.2 0.1 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06471.1 - 0.53 10.1 19.9 1.4 8.8 0.2 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06471.1 - 2.7 8.6 6.9 19 5.9 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EEA06472.1 - 1.2e-12 47.2 9.1 1.9e-05 24.3 0.3 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 EEA06472.1 - 0.00038 19.6 0.7 0.00059 19.0 0.1 1.6 2 0 0 2 2 2 1 CPSF A subunit region Adeno_knob PF00541.12 EEA06472.1 - 0.13 11.9 3.9 0.2 11.2 0.5 2.6 3 0 0 3 3 3 0 Adenoviral fibre protein (knob domain) Dynein_light PF01221.13 EEA06473.1 - 2e-44 149.4 0.8 2.2e-44 149.3 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Tau95 PF09734.4 EEA06474.1 - 7e-53 179.9 0.8 9.3e-53 179.5 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit UCH_1 PF13423.1 EEA06474.1 - 0.031 13.7 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.5 EEA06475.1 - 0.00049 19.4 3.4 0.00049 19.4 2.3 1.7 2 0 0 2 2 2 1 Vps5 C terminal like Zip PF02535.17 EEA06475.1 - 0.3 10.0 3.1 0.43 9.5 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 EEA06475.1 - 2.1 7.4 13.2 4.1 6.4 9.2 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF605 PF04652.11 EEA06475.1 - 2.1 7.6 30.4 3.2 7.0 21.1 1.2 1 0 0 1 1 1 0 Vta1 like Presenilin PF01080.12 EEA06475.1 - 6.4 5.4 11.7 9 4.9 8.1 1.3 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.6 EEA06475.1 - 7 4.6 13.8 13 3.7 9.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 EEA06475.1 - 8.9 4.4 35.8 14 3.7 24.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C97 PF05903.9 EEA06476.1 - 9.2e-34 116.3 0.0 1.3e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain MutL_C PF08676.6 EEA06477.1 - 1.1e-19 70.5 1.5 2.5e-17 62.7 0.1 2.9 3 0 0 3 3 3 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EEA06477.1 - 8.5e-17 60.7 0.1 2.4e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEA06477.1 - 2.7e-10 40.0 3.3 1.3e-09 37.8 2.3 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA06477.1 - 6.7e-06 25.7 0.4 1.4e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PrpR_N PF06506.6 EEA06477.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Propionate catabolism activator zf-RING_5 PF14634.1 EEA06478.1 - 0.0069 16.0 9.8 0.044 13.5 6.8 2.3 1 1 0 1 1 1 1 zinc-RING finger domain Phage_Coat_A PF05357.8 EEA06478.1 - 0.0095 15.4 0.3 0.035 13.6 0.2 2.0 1 0 0 1 1 1 1 Phage Coat Protein A zf-C3HC4_2 PF13923.1 EEA06478.1 - 0.02 14.9 8.2 0.042 13.8 3.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA06478.1 - 0.056 13.1 8.6 0.1 12.3 3.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA06478.1 - 0.081 12.7 8.3 0.32 10.8 5.9 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EEA06478.1 - 0.15 11.7 8.7 0.7 9.6 6.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA06478.1 - 0.22 11.4 8.4 0.26 11.1 2.8 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_MLP1_2 PF07926.7 EEA06479.1 - 0.0027 17.4 19.6 0.0027 17.4 13.6 14.6 5 4 8 13 13 13 3 TPR/MLP1/MLP2-like protein YqzM PF14141.1 EEA06480.1 - 0.0068 16.1 0.6 0.0068 16.1 0.4 2.6 3 0 0 3 3 3 1 YqzM-like protein H_PPase PF03030.11 EEA06480.1 - 1.1 7.4 4.3 1.4 7.0 3.0 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF4149 PF13664.1 EEA06480.1 - 6.3 6.9 7.8 9.4 6.3 2.5 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) YWFCY PF14293.1 EEA06481.1 - 1.1 9.1 8.3 0.8 9.5 1.4 3.1 3 0 0 3 3 3 0 YWFCY protein DUF1664 PF07889.7 EEA06482.1 - 0.026 14.3 6.5 0.028 14.2 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.23 EEA06483.1 - 0.0013 18.1 0.2 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IRK PF01007.15 EEA06484.1 - 2.6e-16 59.3 11.5 3.2e-08 32.7 0.0 2.4 2 1 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 EEA06484.1 - 0.0066 16.1 6.3 0.0066 16.1 4.4 2.0 2 0 0 2 2 2 1 Ion channel Sec61_beta PF03911.11 EEA06485.1 - 1.6e-15 56.5 0.4 2e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Cpn60_TCP1 PF00118.19 EEA06487.1 - 1.3e-135 452.7 3.3 1.8e-135 452.3 2.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTBV_P12 PF06361.6 EEA06487.1 - 0.074 13.3 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Nuc_sug_transp PF04142.10 EEA06488.1 - 5.4e-79 264.7 15.4 5.4e-79 264.7 10.7 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EEA06488.1 - 7.7e-06 26.0 8.0 7.7e-06 26.0 5.5 3.9 2 1 2 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 EEA06488.1 - 1.3 8.6 33.2 0.053 13.1 9.6 3.2 2 2 0 2 2 2 0 Triose-phosphate Transporter family SpoU_methylase PF00588.14 EEA06490.1 - 4.8e-27 94.5 0.0 6.1e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family MAP65_ASE1 PF03999.7 EEA06492.1 - 1.3 7.5 4.1 1.8 7.0 2.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PQ-loop PF04193.9 EEA06493.1 - 2.6e-16 58.8 29.2 5.2e-10 38.7 7.9 3.1 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EEA06493.1 - 9.1 6.2 20.4 0.053 13.4 3.9 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Solute_trans_a PF03619.11 EEA06494.1 - 0.00019 20.8 11.7 0.0004 19.7 8.1 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha CcmD PF04995.9 EEA06494.1 - 0.057 13.1 0.1 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3290 PF11694.3 EEA06494.1 - 0.25 11.0 0.2 0.25 11.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) Proteasome PF00227.21 EEA06495.1 - 5.3e-36 123.6 0.0 6e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Poxvirus PF06227.7 EEA06495.1 - 0.059 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus Mito_carr PF00153.22 EEA06496.1 - 1.4e-36 124.0 1.8 2.2e-17 62.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF464 PF04327.7 EEA06496.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF464) TBPIP PF07106.8 EEA06497.1 - 2e-36 125.0 18.2 2e-36 125.0 12.6 1.9 2 1 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 EEA06497.1 - 0.00054 19.9 1.0 0.11 12.5 0.1 2.7 2 0 0 2 2 2 1 Proteins of 100 residues with WXG IncA PF04156.9 EEA06497.1 - 0.00062 19.4 14.5 0.025 14.1 2.7 2.5 2 0 0 2 2 2 2 IncA protein Cep57_MT_bd PF06657.8 EEA06497.1 - 0.0036 17.2 1.5 0.0036 17.2 1.1 3.2 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF1943 PF09172.6 EEA06497.1 - 0.011 14.6 5.9 0.25 10.1 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) CENP-F_leu_zip PF10473.4 EEA06497.1 - 0.052 13.4 14.1 0.076 12.8 9.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEP-utilisers_N PF05524.8 EEA06497.1 - 0.28 10.9 2.5 3.6 7.4 0.1 2.6 2 1 1 3 3 2 0 PEP-utilising enzyme, N-terminal Uds1 PF15456.1 EEA06497.1 - 0.36 10.8 7.9 7.6 6.5 1.3 2.9 2 1 0 2 2 2 0 Up-regulated During Septation bZIP_1 PF00170.16 EEA06497.1 - 0.38 10.7 15.5 0.35 10.8 2.6 3.9 3 0 0 3 3 3 0 bZIP transcription factor Syntaxin_2 PF14523.1 EEA06497.1 - 1.5 8.9 13.5 0.36 10.8 4.1 3.1 1 1 1 3 3 3 0 Syntaxin-like protein DUF3106 PF11304.3 EEA06497.1 - 2.6 8.4 6.8 6.8 7.1 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) AAA_13 PF13166.1 EEA06497.1 - 2.7 6.3 30.0 0.025 13.0 11.0 2.0 1 1 1 2 2 2 0 AAA domain Mnd1 PF03962.10 EEA06497.1 - 3.2 7.3 20.9 1.3 8.6 11.1 2.4 2 1 0 2 2 2 0 Mnd1 family TFIIE_beta PF02186.10 EEA06497.1 - 3.9 7.5 7.1 2.9 7.9 0.1 3.1 3 1 0 3 3 2 0 TFIIE beta subunit core domain DUF724 PF05266.9 EEA06497.1 - 5 6.6 13.4 0.3 10.6 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DASH_Dad1 PF08649.5 EEA06497.1 - 7.1 6.4 7.5 2.2 8.0 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 DUF4140 PF13600.1 EEA06497.1 - 9.5 6.7 7.5 3.5 8.1 1.5 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF960 PF06124.6 EEA06498.1 - 0.066 13.4 1.9 0.71 10.1 0.1 3.0 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Porin_3 PF01459.17 EEA06501.1 - 0.0046 16.2 11.8 0.021 14.1 8.2 2.3 1 1 0 1 1 1 1 Eukaryotic porin Sfi1 PF08457.5 EEA06502.1 - 0.00028 19.4 0.8 0.00028 19.4 0.5 10.9 5 3 2 9 9 9 7 Sfi1 spindle body protein HSP70 PF00012.15 EEA06503.1 - 1.9e-270 898.0 6.2 2.1e-270 897.8 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA06503.1 - 1.3e-15 56.8 1.2 3.3e-14 52.2 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein DDR PF08841.5 EEA06503.1 - 0.0056 15.5 0.8 0.15 10.8 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 EEA06503.1 - 0.0073 16.1 1.1 0.19 11.5 0.0 3.2 2 1 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.13 EEA06503.1 - 0.011 14.8 2.8 0.051 12.6 0.1 2.7 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EEA06503.1 - 0.015 14.9 0.0 0.093 12.3 0.0 2.2 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain Thioredox_DsbH PF03190.10 EEA06503.1 - 0.15 11.7 0.8 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF255 Aminotran_5 PF00266.14 EEA06504.1 - 7.2e-33 113.8 0.0 2.6e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEA06504.1 - 0.018 14.1 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Exo_endo_phos PF03372.18 EEA06505.1 - 3.2e-11 43.6 0.0 5.1e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EEA06505.1 - 1.1e-10 41.1 0.3 3.8e-10 39.4 0.2 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EEA06505.1 - 5.5e-10 39.0 5.0 5.5e-10 39.0 3.5 2.2 2 0 0 2 2 2 1 GRF zinc finger TA0956 PF11513.3 EEA06505.1 - 0.033 14.2 1.2 0.074 13.1 0.1 2.1 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 CART PF06373.6 EEA06505.1 - 0.047 13.6 0.6 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Nop PF01798.13 EEA06506.1 - 2.5e-56 189.1 0.3 2.5e-56 189.1 0.2 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA06506.1 - 3.4e-25 87.5 0.6 1.4e-24 85.6 0.0 2.4 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEA06506.1 - 8.2e-19 67.5 0.0 3.5e-18 65.5 0.0 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain ABC_tran PF00005.22 EEA06507.1 - 1.7e-29 102.8 0.0 9.5e-20 71.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA06507.1 - 1.1e-12 47.9 37.1 1.2e-12 47.8 10.4 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_25 PF13481.1 EEA06507.1 - 9.8e-07 28.3 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA06507.1 - 4.2e-06 26.9 0.1 0.013 15.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA06507.1 - 1.2e-05 26.1 0.0 0.15 12.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EEA06507.1 - 1.6e-05 23.9 0.0 0.031 13.1 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 EEA06507.1 - 2.4e-05 23.6 2.1 0.048 12.8 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EEA06507.1 - 5.1e-05 23.5 0.1 0.24 11.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEA06507.1 - 5.5e-05 22.9 0.2 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EEA06507.1 - 0.0001 21.9 0.4 0.088 12.4 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EEA06507.1 - 0.00017 21.5 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EEA06507.1 - 0.00022 21.0 0.1 0.009 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA06507.1 - 0.00026 20.6 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EEA06507.1 - 0.00048 19.6 0.0 0.023 14.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 EEA06507.1 - 0.00088 18.2 0.1 0.4 9.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 EEA06507.1 - 0.0012 18.4 0.0 0.35 10.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 EEA06507.1 - 0.0013 18.6 0.6 0.035 14.0 0.5 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 EEA06507.1 - 0.0033 16.8 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EEA06507.1 - 0.0039 17.3 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EEA06507.1 - 0.0044 16.4 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_5 PF07728.9 EEA06507.1 - 0.0047 16.6 0.0 0.45 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEA06507.1 - 0.0048 16.7 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEA06507.1 - 0.0061 16.2 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.12 EEA06507.1 - 0.0065 15.8 0.1 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.1 EEA06507.1 - 0.016 15.5 9.9 0.49 10.6 0.3 3.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA06507.1 - 0.016 14.6 0.1 1 8.7 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EEA06507.1 - 0.022 15.2 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein KaiC PF06745.8 EEA06507.1 - 0.038 13.1 2.2 0.17 10.9 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA PF00004.24 EEA06507.1 - 0.038 14.1 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EEA06507.1 - 0.048 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EEA06507.1 - 0.052 13.2 0.1 0.96 9.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEA06507.1 - 0.056 12.6 0.0 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EEA06507.1 - 0.059 12.9 0.0 6.5 6.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 EEA06507.1 - 0.072 12.3 0.1 0.86 8.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EEA06507.1 - 0.076 12.0 0.0 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EEA06507.1 - 0.079 12.5 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEA06507.1 - 0.17 10.7 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EEA06507.1 - 0.21 11.5 0.3 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEA06507.1 - 0.23 10.1 0.0 2 7.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Mg_chelatase PF01078.16 EEA06507.1 - 0.34 10.0 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EEA06508.1 - 6.3e-33 113.9 0.0 2.3e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA06508.1 - 4e-14 52.6 34.8 3.7e-13 49.5 8.9 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_16 PF13191.1 EEA06508.1 - 6.8e-08 32.7 0.0 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EEA06508.1 - 6.9e-08 33.0 0.1 0.02 15.3 0.0 3.7 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EEA06508.1 - 4.3e-07 29.8 0.1 0.045 13.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EEA06508.1 - 1.1e-06 28.0 0.0 0.045 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEA06508.1 - 0.00011 22.9 0.1 0.71 10.7 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EEA06508.1 - 0.00013 22.0 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA06508.1 - 0.00014 21.0 0.0 0.052 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EEA06508.1 - 0.00025 20.0 0.0 0.015 14.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) T2SE PF00437.15 EEA06508.1 - 0.00033 19.6 0.0 0.0078 15.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 EEA06508.1 - 0.00048 19.9 0.5 0.42 10.4 0.2 2.8 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EEA06508.1 - 0.00098 18.6 0.0 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EEA06508.1 - 0.001 18.8 0.1 0.24 11.0 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase DUF87 PF01935.12 EEA06508.1 - 0.0011 18.8 0.2 0.0085 15.9 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EEA06508.1 - 0.0011 18.8 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEA06508.1 - 0.0013 18.4 0.0 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA06508.1 - 0.0014 17.7 0.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EEA06508.1 - 0.0015 18.6 0.2 0.51 10.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase ArgK PF03308.11 EEA06508.1 - 0.0015 17.3 0.1 0.12 11.1 0.1 2.2 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 EEA06508.1 - 0.0017 17.8 0.1 1.2 8.4 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 EEA06508.1 - 0.002 18.4 1.0 0.38 11.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEA06508.1 - 0.0022 17.2 0.6 3.2 6.9 0.1 3.4 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEA06508.1 - 0.0025 17.2 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA06508.1 - 0.0028 17.9 0.1 4.1 7.7 0.2 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEA06508.1 - 0.0036 17.5 0.2 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EEA06508.1 - 0.0037 16.8 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EEA06508.1 - 0.0051 16.4 0.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EEA06508.1 - 0.012 15.3 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 EEA06508.1 - 0.013 14.7 0.0 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EEA06508.1 - 0.013 15.2 0.2 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EEA06508.1 - 0.014 14.2 0.2 1.7 7.4 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_21 PF13304.1 EEA06508.1 - 0.015 15.2 19.2 0.14 12.0 0.2 5.9 7 0 0 7 7 6 0 AAA domain AAA_30 PF13604.1 EEA06508.1 - 0.13 11.7 0.0 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEA06508.1 - 0.15 10.6 0.0 0.86 8.1 0.1 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 EEA06508.1 - 0.18 11.2 0.0 13 5.1 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEA06509.1 - 2e-33 115.6 0.0 3.4e-17 63.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EEA06509.1 - 1.7e-09 37.0 0.4 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EEA06509.1 - 4.8e-06 27.0 2.0 0.005 17.3 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 EEA06509.1 - 6.6e-06 26.0 1.9 0.0024 17.8 0.4 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EEA06509.1 - 1.4e-05 25.5 19.7 0.0027 18.0 0.2 4.1 4 0 0 4 4 3 3 AAA domain FtsK_SpoIIIE PF01580.13 EEA06509.1 - 3.4e-05 23.3 0.3 0.094 12.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EEA06509.1 - 0.00012 21.1 0.2 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 EEA06509.1 - 0.0003 20.5 1.5 0.43 10.2 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEA06509.1 - 0.00031 19.9 0.1 0.54 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA06509.1 - 0.00034 20.6 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA06509.1 - 0.00055 20.7 0.2 0.24 12.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEA06509.1 - 0.00073 18.4 1.5 0.35 9.6 0.1 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 EEA06509.1 - 0.00076 18.9 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEA06509.1 - 0.0012 18.3 1.9 1 8.7 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EEA06509.1 - 0.0013 18.8 0.8 1.2 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEA06509.1 - 0.0016 18.3 0.1 0.45 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEA06509.1 - 0.0018 18.0 1.1 0.1 12.3 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 EEA06509.1 - 0.0028 17.3 0.1 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 EEA06509.1 - 0.0031 16.7 3.7 0.72 9.0 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EEA06509.1 - 0.0037 16.9 3.9 0.28 10.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ATP_bind_1 PF03029.12 EEA06509.1 - 0.0042 16.6 0.5 0.89 9.0 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EEA06509.1 - 0.0065 16.1 4.5 0.97 9.0 0.1 3.2 3 0 0 3 3 3 2 Archaeal ATPase Dynamin_N PF00350.18 EEA06509.1 - 0.007 16.2 0.5 0.51 10.1 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 EEA06509.1 - 0.013 15.7 3.0 6.2 7.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EEA06509.1 - 0.019 14.5 0.0 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EEA06509.1 - 0.029 13.8 0.3 7.7 6.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EEA06509.1 - 0.052 13.1 0.2 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EEA06509.1 - 0.062 12.7 1.2 6.6 6.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EEA06509.1 - 0.11 12.0 0.5 1.5 8.2 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Fe_dep_repress PF01325.14 EEA06509.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain AAA_24 PF13479.1 EEA06509.1 - 0.17 11.4 0.9 0.6 9.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEA06509.1 - 0.2 10.2 0.7 4.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EEA06509.1 - 0.45 9.2 0.3 4 6.1 0.1 2.0 2 0 0 2 2 2 0 ArgK protein RseC_MucC PF04246.7 EEA06509.1 - 0.58 9.7 4.5 0.89 9.1 0.4 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.22 EEA06510.1 - 1.1e-36 126.1 0.0 4.3e-17 62.7 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.18 EEA06510.1 - 9.8e-21 74.3 30.0 3.3e-14 52.9 6.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region T2SE PF00437.15 EEA06510.1 - 9.2e-08 31.3 0.2 0.0073 15.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EEA06510.1 - 3.2e-07 30.2 0.5 0.0047 16.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA06510.1 - 3.8e-07 29.8 0.0 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EEA06510.1 - 1e-06 28.4 0.2 0.011 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 EEA06510.1 - 2.8e-06 27.4 0.2 0.00065 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EEA06510.1 - 8.1e-06 26.3 0.1 0.14 12.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEA06510.1 - 8.6e-06 25.1 0.7 0.17 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EEA06510.1 - 8.7e-06 25.4 0.2 0.025 14.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EEA06510.1 - 2.4e-05 25.1 3.3 0.11 13.3 0.0 4.0 4 0 0 4 4 2 2 AAA domain SMC_N PF02463.14 EEA06510.1 - 4.5e-05 22.7 0.0 1 8.5 0.0 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EEA06510.1 - 9e-05 22.3 14.1 0.003 17.4 0.1 4.4 4 0 0 4 4 4 2 Domain of unknown function DUF87 MobB PF03205.9 EEA06510.1 - 9.8e-05 22.0 1.3 0.24 11.1 0.0 3.3 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEA06510.1 - 0.0001 21.7 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA06510.1 - 0.00014 21.9 0.0 0.21 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA06510.1 - 0.0002 21.2 0.0 0.07 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA06510.1 - 0.00045 20.0 0.1 0.048 13.3 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase TrwB_AAD_bind PF10412.4 EEA06510.1 - 0.00069 18.3 0.4 0.2 10.2 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 EEA06510.1 - 0.00075 19.0 0.0 0.8 9.1 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EEA06510.1 - 0.00078 18.6 0.0 0.0061 15.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.14 EEA06510.1 - 0.00094 18.6 1.6 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EEA06510.1 - 0.0016 18.2 7.9 0.31 10.8 0.3 3.5 3 0 0 3 3 2 2 Dynamin family DUF258 PF03193.11 EEA06510.1 - 0.0026 16.9 0.8 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EEA06510.1 - 0.0035 16.9 0.5 2.1 7.8 0.1 2.6 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EEA06510.1 - 0.0042 16.7 0.1 0.52 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EEA06510.1 - 0.0051 16.2 0.1 0.57 9.6 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EEA06510.1 - 0.0061 16.8 7.3 0.52 10.6 0.0 4.1 4 0 0 4 4 3 2 AAA domain ArgK PF03308.11 EEA06510.1 - 0.0074 15.1 0.3 0.43 9.2 0.1 2.2 2 0 0 2 2 2 1 ArgK protein Mg_chelatase PF01078.16 EEA06510.1 - 0.013 14.7 0.0 4.6 6.3 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEA06510.1 - 0.039 13.7 0.6 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EEA06510.1 - 0.047 13.3 2.6 1.9 8.1 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA PF00004.24 EEA06510.1 - 0.074 13.2 1.0 0.28 11.3 0.0 2.5 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEA06510.1 - 0.079 12.9 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Apc13p PF05839.6 EEA06511.1 - 0.048 13.6 2.5 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Apc13p protein IncA PF04156.9 EEA06511.1 - 0.99 8.9 7.8 27 4.2 5.4 2.1 1 1 0 1 1 1 0 IncA protein DEAD PF00270.24 EEA06512.1 - 3.5e-32 111.2 0.0 1.2e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06512.1 - 5.9e-24 83.7 0.0 1.7e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA06512.1 - 2.4e-11 43.7 0.2 9.8e-10 38.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEA06512.1 - 0.044 13.7 0.1 0.16 11.8 0.1 2.0 1 1 0 1 1 1 0 Helicase C-terminal domain Ribosomal_L29e PF01779.12 EEA06513.1 - 2.8e-20 71.9 9.1 3.7e-20 71.4 6.3 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_60s PF00428.14 EEA06514.1 - 9.7e-17 61.1 0.0 1.1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein R3H PF01424.17 EEA06515.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain R3H-assoc PF13902.1 EEA06515.1 - 0.0086 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain Brix PF04427.13 EEA06516.1 - 3e-43 147.7 2.4 5.5e-43 146.8 1.7 1.4 1 0 0 1 1 1 1 Brix domain DUF3847 PF12958.2 EEA06516.1 - 0.064 13.0 4.9 0.13 12.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) TRAPP PF04051.11 EEA06516.1 - 0.076 12.5 0.5 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component Glyco_tran_28_C PF04101.11 EEA06516.1 - 0.61 9.7 4.6 12 5.5 1.1 2.9 1 1 2 3 3 3 0 Glycosyltransferase family 28 C-terminal domain tRNA-synt_1_2 PF13603.1 EEA06516.1 - 7.9 5.7 8.2 8.5 5.6 0.0 3.4 3 1 1 4 4 4 0 Leucyl-tRNA synthetase, Domain 2 Ribosomal_S24e PF01282.14 EEA06517.1 - 5.7e-30 102.9 0.0 8.6e-30 102.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e BCAS2 PF05700.6 EEA06518.1 - 9e-14 51.4 5.6 4.5e-13 49.1 3.9 1.8 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3287 PF11690.3 EEA06518.1 - 0.076 13.0 0.1 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Cobl PF09469.5 EEA06518.1 - 4.9 7.2 6.8 0.65 9.9 0.5 2.5 3 1 0 3 3 3 0 Cordon-bleu ubiquitin-like domain Got1 PF04178.7 EEA06519.1 - 1e-18 67.5 13.7 1.1e-18 67.4 9.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 EEA06519.1 - 0.0018 18.2 7.3 0.0018 18.2 5.1 2.2 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) DUF1129 PF06570.6 EEA06519.1 - 0.4 9.9 6.9 0.49 9.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2079 PF09852.4 EEA06519.1 - 0.4 9.3 8.6 0.5 9.0 6.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF973 PF06157.6 EEA06519.1 - 0.78 8.6 7.6 0.96 8.3 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Astro_capsid PF03115.9 EEA06520.1 - 0.12 10.6 10.1 0.14 10.4 7.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 EEA06520.1 - 1.1 7.0 39.2 1.4 6.7 27.2 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EEA06520.1 - 1.8 7.7 22.5 2.3 7.3 15.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EEA06520.1 - 3.1 6.1 30.0 4.8 5.5 20.8 1.2 1 0 0 1 1 1 0 Daxx Family NAD_Gly3P_dh_N PF01210.18 EEA06521.1 - 3.6e-42 143.7 0.0 6.4e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEA06521.1 - 2.1e-33 115.1 0.1 3.3e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus YEATS PF03366.11 EEA06522.1 - 7.6e-30 102.4 0.4 2.1e-29 101.0 0.3 1.8 1 0 0 1 1 1 1 YEATS family DUF3953 PF13129.1 EEA06522.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Syja_N PF02383.13 EEA06523.1 - 1.8e-72 243.8 2.4 1.8e-72 243.8 1.7 2.5 2 1 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 EEA06523.1 - 7.4e-16 58.8 0.0 1.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_3 PF13917.1 EEA06524.1 - 5.2e-06 26.0 1.2 5.2e-06 26.0 0.9 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EEA06524.1 - 2.3e-05 24.1 2.3 2.3e-05 24.1 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EEA06524.1 - 0.0051 16.4 1.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Zinc knuckle V-ATPase_G PF03179.10 EEA06526.1 - 1.3e-23 83.2 8.0 1.6e-23 83.0 5.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EEA06526.1 - 0.71 9.0 12.7 0.59 9.3 5.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF826 PF05696.6 EEA06526.1 - 5.9 7.1 6.2 2.7 8.1 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF826) NTase_sub_bind PF08780.6 EEA06527.1 - 0.055 13.2 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like eIF-3_zeta PF05091.7 EEA06528.1 - 2.8e-158 527.7 0.1 3.2e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF617 PF04759.8 EEA06528.1 - 0.007 16.0 0.1 0.042 13.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF617 Ribosomal_L15e PF00827.12 EEA06529.1 - 8.7e-89 296.1 7.8 1e-88 295.8 5.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Chordopox_A15 PF05846.7 EEA06530.1 - 0.12 12.4 2.1 2.3 8.3 0.0 2.6 2 1 0 2 2 2 0 Chordopoxvirus A15 protein Kelch_4 PF13418.1 EEA06531.1 - 1.6e-17 63.0 7.3 3.3e-06 26.7 0.4 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EEA06531.1 - 6.8e-16 57.9 0.2 4.8e-06 26.5 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA06531.1 - 4.4e-13 48.7 7.4 0.00053 20.0 0.1 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EEA06531.1 - 4.4e-11 42.4 0.9 0.0017 18.2 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EEA06531.1 - 5e-08 32.3 8.1 0.023 14.2 0.1 4.2 4 0 0 4 4 4 3 Kelch motif HATPase_c_3 PF13589.1 EEA06531.1 - 7.1e-07 28.9 1.4 1.2e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BLUF PF04940.7 EEA06531.1 - 0.05 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Sensors of blue-light using FAD Nucleoside_tran PF01733.13 EEA06532.1 - 4.2e-21 75.4 14.6 4.2e-21 75.4 10.1 1.5 2 0 0 2 2 2 1 Nucleoside transporter AHSA1 PF08327.6 EEA06533.1 - 7.6e-13 48.6 0.0 8.7e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein WD40 PF00400.27 EEA06534.1 - 4.9e-87 283.0 22.4 2.1e-14 52.7 0.5 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EEA06534.1 - 5.1e-12 45.6 0.7 9.4e-12 44.7 0.5 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EEA06534.1 - 3.5e-06 26.8 0.1 0.15 11.7 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEA06534.1 - 0.0096 15.5 3.0 4.9 6.9 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EEA06534.1 - 0.026 12.6 3.6 4.9 5.1 0.1 4.3 3 2 1 4 4 4 0 Nucleoporin Nup120/160 DPPIV_N PF00930.16 EEA06534.1 - 0.056 12.0 0.7 18 3.7 0.0 3.7 4 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 EEA06534.1 - 0.063 11.0 0.2 0.28 8.9 0.0 2.0 2 0 0 2 2 2 0 IKI3 family DUF1900 PF08954.6 EEA06534.1 - 0.074 12.5 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) DUF3312 PF11768.3 EEA06534.1 - 0.13 10.4 0.0 3.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) OTU PF02338.14 EEA06535.1 - 1.1e-17 64.7 0.6 3.4e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEA06535.1 - 3.9e-08 32.9 10.6 6.5e-08 32.2 1.3 3.2 1 1 2 3 3 3 1 Peptidase C65 Otubain DUF2316 PF10078.4 EEA06535.1 - 0.097 12.6 0.8 0.29 11.1 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) ABC_tran PF00005.22 EEA06536.1 - 1e-33 116.5 0.0 3e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA06536.1 - 1.2e-16 60.9 38.4 2.9e-13 49.8 9.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region FtsK_SpoIIIE PF01580.13 EEA06536.1 - 9.8e-07 28.4 0.3 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EEA06536.1 - 7.3e-06 25.4 0.3 0.028 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA06536.1 - 1.8e-05 24.9 0.6 0.11 12.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EEA06536.1 - 2.3e-05 23.4 0.1 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SbcCD_C PF13558.1 EEA06536.1 - 5.3e-05 23.0 0.0 0.00066 19.5 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EEA06536.1 - 5.5e-05 23.2 0.2 0.032 14.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EEA06536.1 - 7.5e-05 23.2 1.7 0.29 11.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EEA06536.1 - 9.4e-05 22.3 0.3 0.2 11.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EEA06536.1 - 0.00034 20.5 4.4 0.0074 16.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 NACHT PF05729.7 EEA06536.1 - 0.00035 20.2 0.9 0.38 10.4 0.1 3.1 3 0 0 3 3 3 1 NACHT domain SMC_N PF02463.14 EEA06536.1 - 0.00061 19.0 0.3 1.8 7.7 0.0 3.6 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA06536.1 - 0.00067 20.4 0.0 1.8 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA06536.1 - 0.00094 18.4 0.3 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA06536.1 - 0.0036 16.7 0.0 0.96 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EEA06536.1 - 0.0046 16.8 6.1 0.15 11.8 0.9 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EEA06536.1 - 0.0063 15.9 2.4 0.44 9.9 0.2 2.4 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EEA06536.1 - 0.0065 16.6 0.2 5.8 7.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EEA06536.1 - 0.016 15.5 0.8 5.9 7.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EEA06536.1 - 0.018 14.7 1.5 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEA06536.1 - 0.022 14.1 0.9 3.3 7.0 0.0 3.8 4 1 1 5 5 5 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EEA06536.1 - 0.028 13.9 0.0 7.5 5.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AIG1 PF04548.11 EEA06536.1 - 0.039 13.0 1.0 0.59 9.2 0.0 2.7 3 0 0 3 3 3 0 AIG1 family PRK PF00485.13 EEA06536.1 - 0.052 13.1 1.3 4.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EEA06536.1 - 0.076 11.8 0.1 3.5 6.3 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 EEA06536.1 - 0.086 12.7 0.7 3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EEA06536.1 - 0.1 11.9 0.5 4.8 6.5 0.0 2.8 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.4 EEA06536.1 - 0.13 11.1 0.1 7.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.1 EEA06536.1 - 0.18 12.0 8.0 6.7 6.9 0.2 3.0 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EEA06536.1 - 0.2 10.4 0.1 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Mg_chelatase PF01078.16 EEA06536.1 - 0.22 10.6 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EEA06536.1 - 0.6 9.6 0.1 20 4.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EEA06536.1 - 0.66 9.6 2.2 17 5.1 0.1 2.6 2 0 0 2 2 2 0 NTPase Aa_trans PF01490.13 EEA06537.1 - 1.2e-35 122.8 49.7 1.5e-35 122.4 34.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Thymidylat_synt PF00303.14 EEA06538.1 - 1.1e-111 372.1 0.0 1.5e-111 371.7 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 EEA06538.1 - 5.4e-35 120.3 0.1 9.6e-33 113.0 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase GAGA_bind PF06217.7 EEA06539.1 - 1.5 8.7 15.6 0.11 12.4 7.4 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family ThiF PF00899.16 EEA06540.1 - 1.8e-20 73.1 0.0 4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family GCC2_GCC3 PF07699.8 EEA06541.1 - 1.3e-06 27.8 9.9 1.3e-06 27.8 6.8 4.1 3 1 0 3 3 3 2 GCC2 and GCC3 Synaptobrevin PF00957.16 EEA06542.1 - 0.023 14.2 3.7 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin COX2_TM PF02790.10 EEA06542.1 - 0.074 13.0 0.4 3.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2873 PF11395.3 EEA06542.1 - 2 8.0 5.7 0.91 9.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) SUI1 PF01253.17 EEA06543.1 - 1.5e-11 43.9 0.0 4.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EEA06543.1 - 0.023 14.3 0.0 0.069 12.8 0.0 1.9 1 0 0 1 1 1 0 PUA domain Syja_N PF02383.13 EEA06544.1 - 1.9e-66 223.9 22.1 2e-66 223.9 13.3 2.5 2 1 0 2 2 2 1 SacI homology domain RRP7 PF12923.2 EEA06545.1 - 1.4e-15 57.4 0.9 2.6e-15 56.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EEA06545.1 - 0.0029 17.1 0.5 0.0099 15.4 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06545.1 - 0.02 14.7 0.1 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2018 PF09442.5 EEA06545.1 - 5.4 7.6 10.1 1.9 9.1 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2018) Mito_carr PF00153.22 EEA06546.1 - 3.4e-39 132.4 1.3 9.1e-13 47.7 0.0 3.6 1 1 2 3 3 3 3 Mitochondrial carrier protein HTH_9 PF08221.6 EEA06547.1 - 4.1e-05 23.3 3.7 0.00035 20.3 0.1 3.6 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EEA06547.1 - 1.9 8.0 19.8 0.16 11.4 1.0 4.5 5 1 0 5 5 5 0 TFIIE alpha subunit WD40 PF00400.27 EEA06548.1 - 1.7e-11 43.4 19.2 3.2e-06 26.8 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA06548.1 - 9.2e-10 38.2 0.1 4.8e-09 35.9 0.1 2.3 1 1 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RRM_5 PF13893.1 EEA06549.1 - 0.011 15.5 0.0 0.044 13.6 0.0 2.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.24 EEA06549.1 - 0.047 13.3 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 KH domain SNF2_N PF00176.18 EEA06550.1 - 1.3e-56 191.6 0.0 3.3e-27 95.0 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA06550.1 - 2.5e-13 49.6 0.0 3e-12 46.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EEA06550.1 - 1.5e-06 27.9 4.9 1.5e-06 27.9 3.4 3.3 4 0 0 4 4 4 1 Ring finger domain zf-PARP PF00645.13 EEA06550.1 - 7.5e-06 26.1 0.1 5.8e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-Apc11 PF12861.2 EEA06550.1 - 0.0015 18.3 0.2 0.0072 16.1 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEA06550.1 - 0.003 17.5 5.2 0.003 17.5 3.6 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA06550.1 - 0.0038 17.2 5.2 0.0099 15.9 2.1 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EEA06550.1 - 0.0087 16.0 1.1 0.0087 16.0 0.8 3.3 3 0 0 3 3 3 1 FANCL C-terminal domain Prp31_C PF09785.4 EEA06551.1 - 2.1e-24 86.3 6.4 3.4e-24 85.6 0.9 3.0 3 1 0 3 3 3 1 Prp31 C terminal domain Nop PF01798.13 EEA06551.1 - 1.3e-23 82.9 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA06551.1 - 2.3e-08 33.7 0.7 2.3e-08 33.7 0.5 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain Xpo1 PF08389.7 EEA06551.1 - 0.0074 16.2 1.7 0.12 12.2 0.4 2.7 3 0 0 3 3 3 1 Exportin 1-like protein DUF4477 PF14780.1 EEA06552.1 - 1.5e-05 24.4 2.2 0.018 14.4 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) PAP_RNA-bind PF04926.10 EEA06553.1 - 0.19 11.2 2.5 0.82 9.1 0.5 2.0 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain MMS19_N PF14500.1 EEA06554.1 - 2.8e-25 89.0 8.5 5.6e-10 38.9 0.1 3.7 3 0 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II zf-RING_2 PF13639.1 EEA06555.1 - 0.44 10.4 2.9 0.36 10.6 0.2 2.3 2 0 0 2 2 2 0 Ring finger domain DUF732 PF05305.9 EEA06556.1 - 0.32 11.0 0.5 1 9.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF732) UQ_con PF00179.21 EEA06557.1 - 1.2e-43 147.9 0.0 1.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EEA06557.1 - 5.7e-08 32.3 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 EEA06557.1 - 4.4e-07 29.7 0.0 4e-06 26.6 0.0 2.0 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EEA06557.1 - 0.00034 20.4 0.1 0.0006 19.6 0.0 1.6 1 1 0 1 1 1 1 RWD domain Pkinase PF00069.20 EEA06560.1 - 2.5e-58 197.2 0.0 4.2e-58 196.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06560.1 - 3.8e-17 62.2 0.0 1.1e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA06560.1 - 7.7e-07 28.3 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEA06560.1 - 0.0051 16.5 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA06560.1 - 0.0053 16.3 0.2 0.0095 15.5 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EEA06560.1 - 0.0081 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA06560.1 - 0.08 12.2 0.0 0.81 8.9 0.0 2.2 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL CKS PF01111.14 EEA06561.1 - 8.7e-22 76.7 0.1 1e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Proteasome PF00227.21 EEA06562.1 - 1.1e-56 191.2 0.0 1.3e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA06562.1 - 6.6e-15 54.1 0.4 1.5e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature VIGSSK PF14773.1 EEA06562.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal WD40 PF00400.27 EEA06563.1 - 7.2e-10 38.3 9.2 0.0075 16.1 0.1 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.6 EEA06563.1 - 9.1e-05 22.2 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EEA06563.1 - 0.0038 17.0 0.1 0.018 14.8 0.1 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EEA06563.1 - 0.0093 15.7 0.4 0.032 14.0 0.0 2.1 3 0 0 3 3 3 1 Prp18 domain Agenet PF05641.7 EEA06564.1 - 0.015 15.4 0.3 0.091 12.9 0.1 2.5 2 1 0 2 2 2 0 Agenet domain TUDOR PF00567.19 EEA06564.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Tudor domain DUF2042 PF09743.4 EEA06565.1 - 8.4e-52 176.1 18.1 8.4e-52 176.1 12.6 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2042) B56 PF01603.15 EEA06566.1 - 2.4e-129 431.5 21.4 4.4e-129 430.6 14.8 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Abhydrolase_3 PF07859.8 EEA06567.1 - 2e-34 118.9 0.0 2.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA06567.1 - 5.6e-07 28.6 1.5 5.6e-07 28.6 1.0 2.2 2 1 0 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 EEA06567.1 - 3.4e-05 22.6 0.4 0.0001 21.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) CBFD_NFYB_HMF PF00808.18 EEA06568.1 - 3.7e-14 52.5 0.0 5.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA06568.1 - 4.8e-08 33.0 0.0 8.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EEA06568.1 - 0.0019 18.1 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ras PF00071.17 EEA06569.1 - 5.1e-60 201.5 0.1 6.2e-60 201.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA06569.1 - 8.4e-21 74.6 0.0 1.4e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA06569.1 - 5.5e-14 51.7 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA06569.1 - 2.9e-07 30.4 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA06569.1 - 0.00012 21.5 0.0 0.00031 20.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEA06569.1 - 0.00093 19.3 0.0 0.0028 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EEA06569.1 - 0.0016 17.6 0.1 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EEA06569.1 - 0.0018 17.4 0.0 0.0093 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EEA06569.1 - 0.003 17.4 0.0 0.0076 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EEA06569.1 - 0.0038 16.7 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EEA06569.1 - 0.0073 15.4 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EEA06569.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EEA06569.1 - 0.018 15.0 0.1 0.035 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EEA06569.1 - 0.02 15.2 0.4 0.065 13.5 0.3 2.1 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EEA06569.1 - 0.058 13.0 0.2 0.2 11.3 0.1 1.9 2 1 1 3 3 3 0 NTPase FeoB_N PF02421.13 EEA06569.1 - 0.083 12.1 0.1 0.78 9.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.9 EEA06569.1 - 0.12 12.1 0.1 0.36 10.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EEA06569.1 - 0.12 11.8 0.0 0.42 10.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF916 PF06030.7 EEA06570.1 - 0.067 12.9 1.5 0.15 11.8 0.6 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) DUF3020 PF11223.3 EEA06570.1 - 2.8 8.4 8.0 11 6.5 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DWNN PF08783.6 EEA06570.1 - 5 7.1 7.7 1.5 8.8 1.3 2.7 2 1 1 3 3 3 0 DWNN domain TBCC PF07986.7 EEA06571.1 - 1.4e-12 47.1 5.8 3e-12 46.0 4.0 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EEA06571.1 - 0.014 14.7 4.6 0.035 13.4 3.2 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal TPR_2 PF07719.12 EEA06573.1 - 1.7e-15 55.6 11.8 0.00089 19.0 0.0 7.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06573.1 - 9.4e-15 54.0 14.7 0.001 18.6 0.1 6.1 4 2 2 6 6 6 4 TPR repeat TPR_12 PF13424.1 EEA06573.1 - 1.9e-09 37.3 13.5 0.15 11.9 0.3 6.5 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06573.1 - 2.9e-09 36.1 19.3 0.0041 16.6 0.4 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA06573.1 - 4.5e-08 33.1 24.3 0.00021 21.3 6.6 7.1 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEA06573.1 - 1.7e-06 28.1 0.0 0.00082 19.7 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06573.1 - 1.8e-06 28.0 1.4 0.021 15.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06573.1 - 1.1e-05 24.9 7.2 0.66 9.9 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06573.1 - 0.00046 20.4 0.3 3.7 7.9 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06573.1 - 0.00071 19.1 0.4 0.034 13.9 0.4 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEA06573.1 - 0.00076 18.6 1.6 5 6.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06573.1 - 0.0016 19.0 0.0 0.35 11.6 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06573.1 - 0.0032 17.5 8.2 0.15 12.3 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA06573.1 - 0.0064 16.3 1.7 15 5.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EEA06573.1 - 0.022 14.7 0.0 0.18 11.8 0.0 2.8 1 0 0 1 1 1 0 PPR repeat SET PF00856.23 EEA06574.1 - 1.2e-15 58.2 2.0 3e-15 56.8 0.1 2.5 2 2 0 2 2 2 1 SET domain MFS_1 PF07690.11 EEA06575.1 - 2.9e-26 92.0 24.7 1.6e-25 89.5 9.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CDP-OH_P_transf PF01066.16 EEA06576.1 - 1.4e-08 34.9 28.3 1.6e-06 28.3 19.6 3.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TPR_11 PF13414.1 EEA06577.1 - 3.7e-13 48.9 2.9 3.7e-09 36.1 1.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA06577.1 - 2.5e-09 36.3 11.5 3.7e-05 23.1 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06577.1 - 8.9e-09 34.6 4.8 0.0046 16.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06577.1 - 8.4e-07 29.5 0.2 2.6e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06577.1 - 0.00035 20.4 0.8 0.014 15.3 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA06577.1 - 0.0092 15.8 0.9 0.19 11.6 0.1 3.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EEA06577.1 - 0.0093 16.2 4.0 0.015 15.6 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat NdhM PF10664.4 EEA06577.1 - 0.048 13.5 0.7 0.23 11.3 0.1 2.4 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M TPR_8 PF13181.1 EEA06577.1 - 0.062 13.0 14.2 0.58 10.0 0.2 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06577.1 - 0.072 13.5 5.3 0.41 11.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA06577.1 - 0.52 10.4 7.6 0.14 12.2 1.8 2.6 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 YbfN PF13982.1 EEA06577.1 - 3.2 8.0 8.8 0.34 11.1 0.6 3.1 3 1 0 3 3 3 0 YbfN-like lipoprotein HEAT_2 PF13646.1 EEA06578.1 - 5.7e-30 103.4 0.2 3.6e-13 49.5 0.0 3.9 2 2 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 EEA06578.1 - 9.1e-15 53.5 0.0 0.0097 16.2 0.0 5.8 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.17 EEA06578.1 - 2.2e-07 30.3 0.6 9.9 6.5 0.0 6.8 7 1 1 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EEA06578.1 - 1.1e-05 25.7 0.3 1.7 9.2 0.0 5.4 4 2 4 8 8 8 3 HEAT-like repeat DUF1546 PF07571.8 EEA06578.1 - 0.0034 17.4 0.0 0.97 9.5 0.0 4.0 3 2 1 4 4 4 1 Protein of unknown function (DUF1546) UPF0016 PF01169.14 EEA06579.1 - 2.5e-40 136.4 10.5 4.4e-22 78.0 0.3 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EEA06579.1 - 0.009 15.4 7.0 0.08 12.3 1.4 2.4 2 0 0 2 2 2 2 Integral membrane protein TerC family Cation_efflux PF01545.16 EEA06579.1 - 0.44 9.5 8.4 0.63 9.0 2.5 2.3 2 0 0 2 2 2 0 Cation efflux family DUF204 PF02659.10 EEA06579.1 - 0.49 10.5 12.6 0.78 9.9 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF DUF21 PF01595.15 EEA06579.1 - 0.5 9.6 6.6 1.2 8.4 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF21 ORC5_C PF14630.1 EEA06580.1 - 5.9e-23 81.6 0.0 1.5e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus XPG_N PF00752.12 EEA06581.1 - 8.2e-28 96.6 0.0 2.5e-27 95.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEA06581.1 - 9.1e-23 80.1 0.6 7.8e-22 77.1 0.0 2.9 2 0 0 2 2 2 1 XPG I-region ACI44 PF15270.1 EEA06581.1 - 0.66 10.0 4.5 1 9.3 0.2 2.6 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor DUF3437 PF11919.3 EEA06582.1 - 6e-23 80.3 0.0 1.5e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Nup54 PF13874.1 EEA06583.1 - 1.1e-29 102.8 8.6 1.1e-29 102.8 6.0 2.1 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Ribosomal_L18e PF00828.14 EEA06584.1 - 1.1e-22 80.7 0.1 1.8e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Lipase3_N PF03893.11 EEA06588.1 - 0.041 13.6 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region HSA PF07529.8 EEA06589.1 - 6.7e-18 64.2 1.7 1.8e-17 62.8 1.2 1.7 1 0 0 1 1 1 1 HSA Myb_DNA-bind_6 PF13921.1 EEA06589.1 - 0.0035 17.4 0.1 0.0035 17.4 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain FliC PF12445.3 EEA06589.1 - 1.9 8.6 6.8 0.9 9.6 1.2 2.4 2 0 0 2 2 2 0 Flagellin protein SAP PF02037.22 EEA06590.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EEA06591.1 - 3.5e-06 27.2 0.1 1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 EEA06591.1 - 0.00068 18.9 6.9 0.47 10.1 0.2 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif V-ATPase_C PF03223.10 EEA06592.1 - 6e-99 331.4 4.7 6.9e-99 331.2 3.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C RP-C_C PF11800.3 EEA06593.1 - 0.12 12.0 0.1 0.12 12.0 0.1 1.9 2 1 0 2 2 2 0 Replication protein C C-terminal region FlxA PF14282.1 EEA06593.1 - 0.17 11.8 9.4 0.057 13.3 2.1 2.7 2 0 0 2 2 2 0 FlxA-like protein Allexi_40kDa PF05549.6 EEA06593.1 - 0.24 10.6 5.8 2.9 7.0 0.2 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein Ribosomal_S8 PF00410.14 EEA06593.1 - 2 8.2 10.0 48 3.7 6.9 2.4 1 1 0 1 1 1 0 Ribosomal protein S8 DOT1 PF08123.8 EEA06594.1 - 0.078 12.2 1.2 2.8 7.1 0.1 2.8 3 0 0 3 3 3 0 Histone methylation protein DOT1 Mito_carr PF00153.22 EEA06595.1 - 3e-20 71.7 0.0 2.5e-06 27.0 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1564 PF07600.6 EEA06595.1 - 0.0018 17.6 0.6 0.004 16.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) UQ_con PF00179.21 EEA06596.1 - 9.2e-51 170.9 0.0 1e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA06596.1 - 1e-06 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA06596.1 - 0.00066 19.5 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEA06596.1 - 0.0069 16.0 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain G-gamma PF00631.17 EEA06596.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 GGL domain EPL1 PF10513.4 EEA06597.1 - 2.2e-16 60.5 1.9 4.6e-16 59.4 1.3 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like Helicase_C PF00271.26 EEA06597.1 - 0.0018 18.0 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NTF2 PF02136.15 EEA06598.1 - 3e-30 105.0 0.0 3.4e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HP_OMP_2 PF02521.9 EEA06598.1 - 0.049 12.2 0.2 0.056 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane protein AP2 PF00847.15 EEA06599.1 - 3.3e-07 30.3 0.2 9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 AP2 domain ATP_bind_4 PF01902.12 EEA06600.1 - 7.9e-30 103.8 0.0 1.6e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 ATP-binding region Peptidase_S26 PF10502.4 EEA06601.1 - 1.7e-06 27.5 0.0 3.4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EEA06601.1 - 5.8e-06 25.8 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like XPA_C PF05181.7 EEA06602.1 - 1.9e-09 36.9 1.6 6.2e-09 35.3 0.5 2.0 2 0 0 2 2 2 1 XPA protein C-terminus fn3 PF00041.16 EEA06603.1 - 8.7e-06 25.7 0.5 8.7e-06 25.7 0.4 4.2 4 0 0 4 4 4 1 Fibronectin type III domain DUF3591 PF12157.3 EEA06604.1 - 2.5e-28 98.7 5.5 2.3e-16 59.2 0.0 4.6 4 1 0 4 4 4 3 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EEA06604.1 - 4.1e-14 52.2 0.1 1.3e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.1 EEA06604.1 - 8.1e-05 22.2 0.7 0.00018 21.0 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Pinin_SDK_N PF04697.8 EEA06604.1 - 0.00095 19.2 1.3 0.0023 17.9 0.1 2.3 3 0 0 3 3 3 1 pinin/SDK conserved region zf-CCHC PF00098.18 EEA06604.1 - 0.0025 17.6 0.4 0.0054 16.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle UPF0113 PF03657.8 EEA06606.1 - 9e-11 41.7 0.1 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EEA06606.1 - 0.0022 18.0 0.1 0.0051 16.8 0.0 1.7 1 1 1 2 2 2 1 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EEA06606.1 - 0.023 14.4 0.2 0.051 13.2 0.0 1.6 2 0 0 2 2 2 0 PUA domain Gly_acyl_tr_N PF06021.6 EEA06606.1 - 0.063 12.6 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Ribosomal_L28e PF01778.12 EEA06608.1 - 0.015 15.7 0.2 0.05 13.9 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L28e protein family POR_N PF01855.14 EEA06609.1 - 1.6e-72 243.7 0.2 1.1e-71 240.9 0.4 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.15 EEA06609.1 - 8e-37 126.7 0.0 1.5e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEA06609.1 - 3.2e-27 95.3 0.0 6.1e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR PF01558.13 EEA06609.1 - 4.6e-27 95.0 0.0 9.5e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 EEA06609.1 - 1.6e-21 75.6 0.1 3.1e-20 71.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function NAD_binding_1 PF00175.16 EEA06609.1 - 1.7e-10 41.4 0.0 9.1e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_7 PF12838.2 EEA06609.1 - 4.2e-10 39.8 4.1 4.2e-10 39.8 2.8 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 EEA06609.1 - 2.4e-08 33.7 0.1 7.3e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.1 EEA06609.1 - 6.5e-08 32.7 8.3 0.0015 18.7 0.5 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEA06609.1 - 1.6e-07 30.9 8.2 1.3e-05 24.8 6.5 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 EEA06609.1 - 1.8e-07 30.4 12.8 1.3e-05 24.5 2.2 3.8 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.1 EEA06609.1 - 2.6e-07 31.2 4.9 0.012 16.3 0.5 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EEA06609.1 - 4.7e-07 29.7 4.8 4.7e-07 29.7 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EEA06609.1 - 1e-06 28.9 4.4 4.9e-06 26.7 3.0 2.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EEA06609.1 - 9e-06 25.4 16.3 1.4e-05 24.8 8.6 2.9 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EEA06609.1 - 0.00051 19.7 5.3 0.00051 19.7 3.6 3.5 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EEA06609.1 - 0.0042 17.3 16.1 0.046 14.0 0.9 3.6 3 0 0 3 3 2 2 4Fe-4S binding domain Transketolase_C PF02780.15 EEA06609.1 - 0.01 15.7 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 1 0 Transketolase, C-terminal domain Flavodoxin_5 PF12724.2 EEA06609.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Fer4_18 PF13746.1 EEA06609.1 - 0.076 13.4 10.2 0.47 10.9 0.2 3.2 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EEA06609.1 - 0.67 10.5 9.0 1.2 9.8 0.6 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.1 EEA06609.1 - 3.2 8.1 14.2 13 6.3 2.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Saccharop_dh PF03435.13 EEA06610.1 - 2.4e-08 33.3 0.0 3.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ldl_recept_a PF00057.13 EEA06610.1 - 0.2 11.6 1.8 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A RRM_6 PF14259.1 EEA06611.1 - 2.5e-07 30.5 0.0 2e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA06611.1 - 1.3e-06 27.9 0.0 0.0029 17.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06611.1 - 0.0018 18.1 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA06611.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif bPH_5 PF10882.3 EEA06611.1 - 0.085 12.6 1.5 0.31 10.8 0.0 2.4 2 1 0 2 2 2 0 Bacterial PH domain Bacteroid_pep PF14406.1 EEA06611.1 - 0.95 9.6 8.2 0.17 12.0 1.6 2.5 2 1 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes NAP PF00956.13 EEA06612.1 - 3.7e-63 212.9 0.2 3.7e-63 212.9 0.2 2.2 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.7 EEA06612.1 - 0.092 10.6 13.8 0.11 10.4 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EEA06612.1 - 0.25 10.0 21.4 0.41 9.3 14.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.8 EEA06612.1 - 0.6 7.8 15.3 0.85 7.3 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.8 EEA06612.1 - 0.73 9.4 10.0 1.7 8.1 6.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region AhpC-TSA PF00578.16 EEA06614.1 - 1.3e-36 125.0 0.0 1.6e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEA06614.1 - 1.4e-17 63.5 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEA06614.1 - 9.6e-12 44.3 0.0 1.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kazal_2 PF07648.10 EEA06615.1 - 2.7e-42 142.4 47.3 1.3e-08 34.5 0.7 7.9 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EEA06615.1 - 1.6e-37 127.2 66.8 2.8e-07 30.4 1.2 8.4 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain Prefoldin PF02996.12 EEA06616.1 - 2.1e-08 33.8 0.5 6.6e-08 32.2 0.3 1.8 1 1 0 1 1 1 1 Prefoldin subunit DUF3287 PF11690.3 EEA06616.1 - 0.039 14.0 0.8 0.068 13.2 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) MerR-DNA-bind PF09278.6 EEA06616.1 - 0.5 10.7 6.3 3.6 8.0 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding ASF1_hist_chap PF04729.8 EEA06617.1 - 9.7e-64 213.6 0.0 1.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DNA_topoisoIV PF00521.15 EEA06619.1 - 6.5e-116 387.6 9.5 1.2e-82 278.0 0.0 3.8 3 1 0 3 3 3 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EEA06619.1 - 1.7e-27 95.7 0.4 1.7e-27 95.7 0.3 2.7 3 0 0 3 3 3 1 DNA gyrase B Toprim PF01751.17 EEA06619.1 - 2.4e-12 46.6 0.7 8.4e-11 41.7 0.0 3.7 3 0 0 3 3 3 1 Toprim domain HATPase_c PF02518.21 EEA06619.1 - 1e-06 28.4 0.1 4.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-met2 PF12907.2 EEA06620.1 - 4.4e-15 55.3 2.7 6e-15 54.9 1.9 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EEA06620.1 - 1.2e-09 38.6 0.7 1.7e-09 38.2 0.5 1.2 1 0 0 1 1 1 1 4F5 protein family IBR PF01485.16 EEA06620.1 - 0.1 12.4 0.8 0.14 12.0 0.5 1.2 1 0 0 1 1 1 0 IBR domain DUF4519 PF15012.1 EEA06620.1 - 0.14 12.0 4.0 1.6 8.7 2.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) Yip1 PF04893.12 EEA06621.1 - 1.3e-06 28.0 13.3 1.9e-06 27.5 9.2 1.2 1 0 0 1 1 1 1 Yip1 domain UDPGP PF01704.13 EEA06622.1 - 5.4e-37 127.2 1.7 1e-36 126.3 1.2 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase V-SNARE_C PF12352.3 EEA06623.1 - 2.1e-12 46.9 3.2 6.8e-12 45.2 2.2 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEA06623.1 - 0.029 14.0 2.3 0.029 14.0 1.6 2.5 2 1 0 2 2 2 0 Sec20 OmpH PF03938.9 EEA06623.1 - 4.7 7.1 9.6 71 3.2 6.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 EEA06623.1 - 9.2 6.5 12.2 3.9 7.7 0.8 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DnaJ PF00226.26 EEA06624.1 - 1.5e-26 91.8 4.4 2.5e-26 91.1 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEA06624.1 - 2.1e-26 91.6 3.1 5e-22 77.6 0.3 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain ATP-grasp_5 PF13549.1 EEA06626.1 - 1.8e-61 207.2 0.0 4.9e-61 205.7 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EEA06626.1 - 2.1e-51 173.1 0.2 4.4e-51 172.1 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEA06626.1 - 2.8e-22 79.0 0.0 1.4e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain Acetyltransf_3 PF13302.1 EEA06626.1 - 2.3e-09 37.5 0.0 4.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA06626.1 - 3e-09 36.8 0.0 7.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEA06626.1 - 8e-08 32.3 0.0 3.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 EEA06626.1 - 1.5e-06 28.5 0.3 5.4e-06 26.8 0.2 2.0 1 1 0 1 1 1 1 CoA binding domain ATP-grasp_4 PF13535.1 EEA06626.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_10 PF13673.1 EEA06626.1 - 0.00013 22.0 0.0 0.0004 20.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP-grasp_2 PF08442.5 EEA06626.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEA06626.1 - 0.0032 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Acetyltransf_7 PF13508.1 EEA06626.1 - 0.004 17.2 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Thioredoxin_6 PF13848.1 EEA06627.1 - 8.2e-06 25.7 6.1 0.08 12.7 0.5 3.5 2 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 EEA06627.1 - 8.7e-06 25.3 0.6 0.077 12.6 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin NTP_transferase PF00483.18 EEA06628.1 - 3.1e-37 128.2 0.0 4.8e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EEA06628.1 - 1.1e-11 43.6 8.4 3.7e-06 26.1 0.4 4.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEA06628.1 - 9.6e-07 29.0 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEA06628.1 - 0.016 14.7 6.3 0.017 14.6 1.9 2.9 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase ArfGap PF01412.13 EEA06629.1 - 8.9e-40 135.1 0.2 8.9e-40 135.1 0.2 2.8 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Nexin_C PF08628.7 EEA06629.1 - 0.11 12.5 0.1 0.57 10.2 0.0 2.0 1 1 1 2 2 2 0 Sorting nexin C terminal zf-C3HC4_2 PF13923.1 EEA06630.1 - 3.1e-05 23.9 16.8 3.1e-05 23.9 11.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA06630.1 - 0.00017 21.2 10.7 0.0005 19.6 7.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA06630.1 - 0.00023 20.9 14.5 0.00063 19.5 10.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA06630.1 - 0.00026 20.6 11.6 0.0011 18.6 8.0 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA06630.1 - 0.00036 20.3 11.9 0.0027 17.5 8.5 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA06630.1 - 0.012 15.2 7.3 0.012 15.2 5.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger SWIRM PF04433.12 EEA06631.1 - 3.9e-30 103.8 1.0 1.7e-28 98.5 0.0 2.8 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EEA06631.1 - 3.2e-10 39.8 0.0 8.5e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA06631.1 - 1.3e-07 31.5 0.0 4.1e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_1 PF00036.27 EEA06635.1 - 4.8e-12 44.2 0.8 7.7e-05 21.7 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EEA06635.1 - 3.7e-11 41.9 0.3 0.00034 20.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EEA06635.1 - 5.6e-10 39.2 0.2 0.00031 20.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA06635.1 - 4.4e-08 32.0 0.2 0.0016 17.7 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEA06635.1 - 1.9e-07 30.6 7.3 0.00057 19.4 0.2 4.1 3 2 2 5 5 5 4 EF-hand domain pair Toprim PF01751.17 EEA06635.1 - 0.0042 17.0 0.0 0.13 12.2 0.0 2.2 1 1 1 2 2 2 1 Toprim domain Caleosin PF05042.8 EEA06635.1 - 0.0047 16.5 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.1 EEA06635.1 - 0.0062 16.4 0.1 0.039 13.8 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain DUF751 PF05421.6 EEA06637.1 - 0.2 11.9 3.6 3.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF751) zf-Tim10_DDP PF02953.10 EEA06638.1 - 1.7e-17 62.4 2.0 2.1e-17 62.1 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ING PF12998.2 EEA06639.1 - 2e-15 56.9 2.0 2e-15 56.9 1.4 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding CBFD_NFYB_HMF PF00808.18 EEA06640.1 - 9.7e-05 22.3 1.5 0.00022 21.2 1.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA06640.1 - 0.035 14.2 0.3 0.081 13.0 0.2 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Pro_isomerase PF00160.16 EEA06641.1 - 1.2e-48 165.2 0.2 1.3e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDOST_48kD PF03345.9 EEA06642.1 - 3e-90 302.7 3.6 3.4e-90 302.5 2.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Baculo_11_kDa PF06143.6 EEA06642.1 - 0.068 12.5 2.8 0.17 11.2 2.0 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1355 PF07090.6 EEA06642.1 - 0.11 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) Metallophos PF00149.23 EEA06643.1 - 1.1e-29 103.2 3.4 3.1e-29 101.8 2.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_8 PF13833.1 EEA06643.1 - 6.4e-11 41.7 0.7 7.8e-08 31.8 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA06643.1 - 3.8e-10 38.3 3.4 0.0013 17.8 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEA06643.1 - 9.4e-10 37.5 0.5 0.0019 17.9 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EEA06643.1 - 1.9e-09 37.5 4.2 0.00097 19.2 0.5 2.9 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA06643.1 - 0.0069 15.6 1.2 5.1 6.6 0.0 3.3 3 0 0 3 3 3 2 EF hand dCMP_cyt_deam_1 PF00383.17 EEA06644.1 - 2.9e-15 55.7 0.1 4.5e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEA06644.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase Pkinase PF00069.20 EEA06646.1 - 1.2e-45 155.7 0.0 2.4e-45 154.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06646.1 - 1.4e-17 63.6 0.0 2.7e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EEA06646.1 - 0.0052 15.8 0.1 0.4 9.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.18 EEA06647.1 - 2.3e-113 378.3 0.1 5.7e-113 377.0 0.1 1.6 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA06647.1 - 5.6e-18 65.5 0.0 1.5e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA06647.1 - 1.8e-07 30.5 0.2 6.3e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA06647.1 - 0.0058 16.3 0.0 0.02 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA06647.1 - 0.0074 15.8 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA06647.1 - 0.01 15.3 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EEA06647.1 - 0.059 13.5 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) EGF_CA PF07645.10 EEA06648.1 - 7e-21 73.9 76.5 1.9e-10 40.5 5.4 7.0 7 0 0 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.2 EEA06648.1 - 1.4e-17 62.9 39.8 1.4e-08 34.1 2.7 7.0 7 0 0 7 7 7 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EEA06648.1 - 2.4e-09 37.1 67.7 2.7e-07 30.6 8.1 7.0 7 0 0 7 7 7 4 Coagulation Factor Xa inhibitory site PAN_4 PF14295.1 EEA06648.1 - 2.3e-07 30.4 0.2 2.3e-07 30.4 0.1 3.0 2 0 0 2 2 2 1 PAN domain EGF_3 PF12947.2 EEA06648.1 - 0.00019 21.2 7.7 0.00072 19.4 1.4 6.8 7 0 0 7 7 7 4 EGF domain EGF PF00008.22 EEA06648.1 - 0.012 15.5 1.6 0.012 15.5 1.1 7.2 8 0 0 8 8 8 0 EGF-like domain hEGF PF12661.2 EEA06648.1 - 0.11 12.5 0.4 0.11 12.5 0.3 5.9 6 0 0 6 6 6 0 Human growth factor-like EGF Auto_anti-p27 PF06677.7 EEA06649.1 - 0.049 13.4 0.5 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Transpos_assoc PF13963.1 EEA06649.1 - 0.057 13.4 0.6 0.6 10.1 0.1 2.2 2 0 0 2 2 2 0 Transposase-associated domain DUF35_N PF12172.3 EEA06649.1 - 0.063 13.2 1.5 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HECT_2 PF09814.4 EEA06649.1 - 0.2 10.3 1.3 0.32 9.6 0.1 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-AN1 PF01428.11 EEA06649.1 - 0.98 9.3 4.5 9 6.2 0.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger Polysacc_syn_2C PF08485.5 EEA06650.1 - 0.084 12.3 0.5 0.21 11.1 0.4 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal DUF2969 PF11184.3 EEA06650.1 - 0.24 11.5 1.6 0.33 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) Vps26 PF03643.10 EEA06651.1 - 2.7e-99 331.3 2.3 3.3e-99 331.1 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.17 EEA06651.1 - 0.0033 17.5 0.3 0.018 15.1 0.1 2.2 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEA06651.1 - 0.012 15.4 2.4 12 5.6 0.1 4.3 3 2 1 4 4 4 0 Arrestin (or S-antigen), N-terminal domain CTP_transf_1 PF01148.15 EEA06652.1 - 0.0056 16.3 66.9 0.21 11.2 34.5 4.1 1 1 1 2 2 2 1 Cytidylyltransferase family ORC4_C PF14629.1 EEA06653.1 - 8e-15 54.7 2.4 1.4e-14 53.9 1.7 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EEA06653.1 - 0.032 14.2 0.0 0.084 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Kinetocho_Slk19 PF12709.2 EEA06653.1 - 0.054 13.5 0.6 0.14 12.2 0.4 1.7 1 0 0 1 1 1 0 Central kinetochore-associated zf-LYAR PF08790.6 EEA06654.1 - 4.1e-14 51.9 7.3 4.1e-14 51.9 5.1 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 EEA06654.1 - 0.0062 16.8 5.3 0.0098 16.2 2.4 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger Transposase_24 PF03004.9 EEA06654.1 - 0.012 15.4 1.9 0.016 15.0 0.8 1.6 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Crust_neurohorm PF01147.12 EEA06654.1 - 2 7.7 12.8 0.41 9.9 5.9 2.2 2 1 1 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family NPR2 PF06218.6 EEA06655.1 - 3.3e-42 144.6 13.3 1.1e-37 129.8 4.8 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF4629 PF15442.1 EEA06655.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) CorA PF01544.13 EEA06656.1 - 0.0015 17.6 0.8 0.0042 16.1 0.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TruD PF01142.13 EEA06657.1 - 1.8e-43 148.6 0.1 1.2e-40 139.3 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PCI PF01399.22 EEA06658.1 - 3.5e-11 43.3 1.4 5.9e-11 42.6 0.3 1.9 2 0 0 2 2 2 1 PCI domain eIF3_N PF09440.5 EEA06658.1 - 0.00079 19.6 0.6 0.0026 17.9 0.4 1.9 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain RQC PF09382.5 EEA06658.1 - 0.065 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 RQC domain DUF1084 PF06454.6 EEA06659.1 - 1.6e-11 43.8 19.6 2e-11 43.4 13.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) RRM_1 PF00076.17 EEA06660.1 - 3.4e-14 52.2 0.0 2.1e-09 36.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06660.1 - 1e-06 28.4 0.0 0.0012 18.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06660.1 - 0.00078 19.3 0.0 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bromo_TP PF07524.8 EEA06661.1 - 2e-05 24.2 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EEA06661.1 - 0.007 16.3 1.6 0.016 15.2 1.1 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.10 EEA06661.1 - 0.056 13.2 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit ThiF PF00899.16 EEA06662.1 - 3.2e-32 111.1 0.2 8.6e-32 109.8 0.2 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EEA06662.1 - 2.9e-25 87.6 0.0 1e-24 85.8 0.0 2.0 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EEA06662.1 - 3.1e-20 72.0 0.1 8.1e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EEA06662.1 - 2.2e-18 65.3 4.0 4.9e-18 64.2 2.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EEA06662.1 - 0.047 13.7 0.3 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EEA06662.1 - 0.051 12.5 0.9 0.2 10.5 0.6 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox PF00070.22 EEA06662.1 - 0.051 13.9 0.2 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EEA06662.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.11 EEA06663.1 - 6.1e-19 67.9 34.4 6.1e-19 67.9 23.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EEA06663.1 - 9.6e-09 33.8 27.2 4.5e-06 25.0 1.8 3.4 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EEA06663.1 - 4.8e-06 25.4 14.6 4.8e-06 25.4 10.1 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1228 PF06779.9 EEA06663.1 - 0.054 13.5 0.1 0.054 13.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Proteasome PF00227.21 EEA06664.1 - 2.5e-53 180.1 0.0 3.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA06664.1 - 8.1e-15 53.8 0.0 1.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Dynactin_p62 PF05502.8 EEA06665.1 - 2.2e-25 89.4 16.6 1.3e-18 67.1 7.6 2.2 2 0 0 2 2 2 2 Dynactin p62 family ETRAMP PF09716.5 EEA06666.1 - 0.051 13.5 2.0 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.1 EEA06666.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DnaJ PF00226.26 EEA06667.1 - 1.6e-08 34.1 0.4 3.6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1754 PF08555.5 EEA06668.1 - 6.9e-05 23.3 8.6 0.00043 20.8 5.9 1.9 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CtaG_Cox11 PF04442.9 EEA06670.1 - 0.032 14.0 0.2 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 tRNA_synt_1c_R2 PF04557.10 EEA06670.1 - 6.7 7.4 14.4 0.25 12.0 4.1 2.2 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 LSM PF01423.17 EEA06674.1 - 2.5e-16 58.9 0.1 3.1e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Gemin6 PF06372.7 EEA06674.1 - 0.091 12.0 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein PP2C PF00481.16 EEA06675.1 - 4e-50 170.5 0.2 6e-48 163.4 0.2 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA06675.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C ERM PF00769.14 EEA06676.1 - 0.0042 16.6 2.8 0.0042 16.6 1.9 1.7 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DivIC PF04977.10 EEA06676.1 - 0.0084 15.5 9.3 0.01 15.2 1.5 2.5 2 0 0 2 2 2 1 Septum formation initiator BaffR-Tall_bind PF09256.5 EEA06676.1 - 0.08 12.5 0.6 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding IFP_35_N PF07334.8 EEA06676.1 - 2.4 8.1 7.9 6 6.9 0.0 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rabaptin PF03528.10 EEA06676.1 - 4.9 7.1 12.1 9.5 6.1 1.1 2.4 2 0 0 2 2 2 0 Rabaptin DUF2207 PF09972.4 EEA06678.1 - 0.17 10.4 2.9 0.2 10.2 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kelch_3 PF13415.1 EEA06681.1 - 1.9e-33 113.8 2.9 4.2e-06 26.7 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EEA06681.1 - 8.1e-27 92.6 9.8 4.6e-08 32.8 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EEA06681.1 - 1.5e-26 91.8 10.9 9e-07 28.5 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA06681.1 - 2.1e-26 90.9 17.3 9.1e-06 25.6 0.1 6.5 4 1 2 6 6 6 6 Kelch motif DUF4110 PF13422.1 EEA06681.1 - 5.9e-22 77.3 2.3 5.9e-22 77.3 1.6 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 EEA06681.1 - 4.3e-12 45.3 27.5 1.4e-05 24.5 0.3 7.1 7 1 0 7 7 7 5 Kelch motif Kelch_2 PF07646.10 EEA06681.1 - 1.1e-10 40.8 21.0 0.0011 18.6 0.3 7.1 6 1 0 6 6 6 4 Kelch motif His_Phos_1 PF00300.17 EEA06681.1 - 0.36 10.9 4.3 0.4 10.7 0.2 2.6 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) Mpp10 PF04006.7 EEA06682.1 - 2.6e-50 171.4 47.9 1.1e-47 162.7 27.9 3.0 1 1 1 2 2 2 2 Mpp10 protein PRMT5 PF05185.11 EEA06683.1 - 2.2e-130 435.6 7.0 2.6e-130 435.3 4.9 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EEA06683.1 - 0.001 18.6 0.1 0.0041 16.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain AAR2 PF05282.6 EEA06684.1 - 1.4e-65 221.6 0.0 1.7e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Death PF00531.17 EEA06684.1 - 0.074 12.8 0.1 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Death domain Mito_carr PF00153.22 EEA06685.1 - 7.5e-69 227.5 3.1 7.7e-25 86.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAMP PF00672.20 EEA06685.1 - 0.22 11.7 1.2 0.32 11.2 0.2 1.7 2 0 0 2 2 2 0 HAMP domain Kelch_1 PF01344.20 EEA06686.1 - 2.8e-51 170.8 17.3 1.7e-10 40.2 1.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EEA06686.1 - 1e-49 165.6 17.1 3.6e-09 36.5 0.5 8.3 7 1 1 8 8 8 7 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA06686.1 - 1.3e-42 142.2 18.3 5.7e-10 38.9 0.1 7.0 4 2 3 7 7 7 6 Kelch motif Kelch_5 PF13854.1 EEA06686.1 - 2e-42 142.5 4.6 6.8e-08 32.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EEA06686.1 - 3e-42 142.1 18.6 2.5e-08 33.5 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EEA06686.1 - 7.6e-32 107.8 17.1 1.1e-06 28.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 EEA06686.1 - 5e-15 55.4 0.6 1.4e-14 54.0 0.4 1.8 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EEA06686.1 - 1.9e-05 24.4 1.8 6.9e-05 22.6 0.3 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch CTD_bind PF04818.8 EEA06687.1 - 2.8e-11 43.4 0.2 1e-10 41.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PP2C PF00481.16 EEA06688.1 - 3.2e-35 121.7 0.0 6.5e-34 117.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA06688.1 - 0.027 14.1 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PAP_assoc PF03828.14 EEA06689.1 - 7.8e-09 35.3 0.3 2e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEA06689.1 - 1.8e-05 24.9 0.0 6.9e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Carb_kinase PF01256.12 EEA06691.1 - 2e-46 158.2 0.0 2e-32 112.4 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate kinase E2F_TDP PF02319.15 EEA06692.1 - 1.1e-09 37.7 0.2 4.3e-09 35.8 0.1 2.0 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Streptin-Immun PF11083.3 EEA06692.1 - 0.038 13.9 0.2 0.32 11.0 0.1 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Rac1 PF09632.5 EEA06692.1 - 0.066 12.2 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Rac1-binding domain Pox_LP_H2 PF03356.10 EEA06692.1 - 0.07 12.8 0.3 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Viral late protein H2 Proteasome PF00227.21 EEA06693.1 - 1.3e-60 203.9 0.1 2.5e-60 203.0 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA06693.1 - 7.4e-12 44.3 0.1 3.3e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 EEA06693.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein HSP90 PF00183.13 EEA06694.1 - 1.8e-139 465.5 25.2 7.7e-137 456.8 10.2 2.6 1 1 2 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.1 EEA06694.1 - 1.6e-12 47.2 0.1 1.6e-12 47.2 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA06694.1 - 7.6e-09 35.2 0.1 1.6e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YycC PF14174.1 EEA06694.1 - 0.024 14.2 0.1 0.024 14.2 0.1 2.6 2 0 0 2 2 2 0 YycC-like protein TPR_11 PF13414.1 EEA06695.1 - 1.9e-36 123.4 14.4 4.8e-11 42.1 0.3 6.5 3 1 4 7 7 7 5 TPR repeat TPR_2 PF07719.12 EEA06695.1 - 1.6e-27 93.1 3.4 0.0017 18.1 0.1 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06695.1 - 6e-26 88.9 5.2 2.1e-07 30.2 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EEA06695.1 - 7.1e-24 83.7 17.8 4.4e-10 39.5 1.4 6.1 3 3 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EEA06695.1 - 6.1e-19 66.3 1.4 0.0033 17.0 0.0 8.1 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06695.1 - 4.8e-17 62.1 0.1 5.2e-08 33.3 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06695.1 - 1.7e-15 56.7 10.7 2.4e-05 24.1 0.0 6.6 4 1 6 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06695.1 - 3.6e-13 49.6 5.2 0.0023 18.2 0.4 6.4 4 1 2 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06695.1 - 2.8e-11 42.3 4.7 0.088 12.6 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA06695.1 - 5.2e-11 42.1 0.0 0.3 11.8 0.1 6.3 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06695.1 - 9.8e-11 40.9 1.7 0.46 10.8 0.0 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA06695.1 - 5e-06 26.2 0.7 0.083 12.7 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06695.1 - 7.5e-06 26.0 4.6 10 6.8 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 EEA06695.1 - 0.0051 15.9 0.3 0.99 8.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEA06695.1 - 0.028 13.6 0.2 1.7 7.9 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR Coatomer_E PF04733.9 EEA06695.1 - 0.036 13.2 0.1 0.91 8.6 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_3 PF07720.7 EEA06695.1 - 0.044 13.5 0.6 1.9 8.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA06695.1 - 0.091 12.7 0.1 24 5.0 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA06695.1 - 0.48 10.3 5.2 20 5.1 0.1 4.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EEA06695.1 - 0.97 9.3 5.1 5.5 6.9 0.2 3.9 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EEA06696.1 - 1.1e-15 56.6 0.1 0.54 11.0 0.0 8.9 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06696.1 - 6.1e-13 48.9 1.8 0.021 15.1 0.2 6.0 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06696.1 - 2e-10 41.0 0.1 1.3 9.8 0.0 6.8 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06696.1 - 1.3e-06 28.2 11.6 0.25 11.3 0.1 7.1 5 2 4 9 9 9 1 Tetratricopeptide repeat Suf PF05843.9 EEA06696.1 - 2e-06 27.7 21.0 3.3e-05 23.7 1.6 4.8 3 2 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EEA06696.1 - 8.3e-06 25.3 10.8 1.3 9.1 0.2 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06696.1 - 0.00051 19.6 9.9 5.3 6.7 0.0 6.8 7 1 2 9 9 9 1 TPR repeat HAT PF02184.11 EEA06696.1 - 0.00076 19.1 11.9 2.6 7.8 0.7 6.3 6 1 0 6 6 6 2 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 EEA06696.1 - 0.0021 18.4 5.1 17 6.1 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06696.1 - 0.019 15.1 8.5 1.6 9.1 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06696.1 - 0.036 13.8 10.1 3.6 7.5 0.5 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06696.1 - 0.052 13.3 3.9 5 7.1 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EEA06696.1 - 0.43 10.3 17.5 0.052 13.3 1.5 5.4 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.23 EEA06696.1 - 1.7 8.4 8.3 26 4.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EEA06697.1 - 8.3e-13 47.9 6.8 8.3e-13 47.9 4.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA06697.1 - 4.9e-09 36.0 6.3 1.6e-08 34.4 4.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA06697.1 - 2.3e-08 34.0 4.8 2.3e-08 34.0 3.3 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA06697.1 - 1.8e-07 30.7 7.4 2.6e-07 30.1 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA06697.1 - 1.9e-07 30.6 3.4 4.1e-07 29.5 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA06697.1 - 1.1e-06 28.2 4.6 2.4e-06 27.1 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA06697.1 - 5.8e-06 25.9 1.6 1.2e-05 24.9 0.4 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA06697.1 - 0.033 14.0 4.8 0.091 12.6 3.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EEA06697.1 - 0.042 13.9 7.3 0.12 12.4 5.0 1.9 1 0 0 1 1 1 0 RING-variant domain Rtf2 PF04641.7 EEA06697.1 - 0.081 12.1 0.4 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Apc11 PF12861.2 EEA06697.1 - 0.12 12.2 8.4 0.04 13.7 2.8 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA06697.1 - 0.14 11.7 3.9 0.37 10.4 2.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2175 PF09943.4 EEA06697.1 - 0.44 10.6 1.9 1.3 9.1 1.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) LRR_4 PF12799.2 EEA06699.1 - 3.9e-05 23.1 7.2 0.001 18.6 0.7 9.4 5 3 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA06699.1 - 0.0018 18.0 57.0 0.73 10.0 0.0 13.1 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_7 PF13504.1 EEA06699.1 - 0.14 12.4 0.1 0.14 12.4 0.0 13.3 14 2 1 15 15 15 0 Leucine rich repeat LRR_6 PF13516.1 EEA06699.1 - 0.18 11.9 0.1 0.18 11.9 0.1 14.6 14 2 1 15 15 15 0 Leucine Rich repeat Cys_rich_VLP PF14194.1 EEA06699.1 - 0.91 9.3 9.1 1.8 8.3 0.7 3.2 3 0 0 3 3 3 0 Cysteine-rich VLP IBR PF01485.16 EEA06700.1 - 2.9e-14 52.6 35.3 1.3e-09 37.7 7.7 3.1 3 0 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EEA06700.1 - 0.028 14.4 1.7 0.028 14.4 1.2 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RloB PF13707.1 EEA06700.1 - 2.6 7.6 12.2 0.043 13.4 2.2 2.3 2 0 0 2 2 2 0 RloB-like protein DnaJ PF00226.26 EEA06701.1 - 6.8e-19 67.3 0.4 1.2e-18 66.5 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3395 PF11875.3 EEA06701.1 - 8.8e-08 31.9 0.1 8.8e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DUSP PF06337.7 EEA06701.1 - 0.3 11.5 4.4 0.45 10.9 0.1 3.1 2 1 1 3 3 3 0 DUSP domain PP-binding_2 PF14573.1 EEA06702.1 - 6.6e-11 42.1 0.3 1.2e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-carrier PP-binding PF00550.20 EEA06702.1 - 5.8e-07 29.6 0.1 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RNA_pol_Rpb2_6 PF00562.23 EEA06703.1 - 1e-124 416.2 0.0 1.7e-124 415.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA06703.1 - 7.7e-56 188.2 0.0 1.1e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEA06703.1 - 6.1e-45 152.9 0.0 9.9e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEA06703.1 - 2.7e-29 101.2 0.1 6.2e-29 100.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EEA06703.1 - 3.1e-22 78.0 0.0 9.4e-22 76.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEA06703.1 - 2.4e-21 75.4 0.6 5e-21 74.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 EEA06703.1 - 2.5e-17 62.4 0.1 8.1e-17 60.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 polyprenyl_synt PF00348.12 EEA06704.1 - 2.2e-40 138.1 0.0 7.2e-40 136.4 0.0 1.8 1 1 0 1 1 1 1 Polyprenyl synthetase HAD_2 PF13419.1 EEA06705.1 - 0.0018 18.5 0.0 0.0049 17.1 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EEA06705.1 - 0.036 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase DUF2608 PF11019.3 EEA06705.1 - 0.039 12.9 0.1 0.063 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) COG4 PF08318.7 EEA06706.1 - 1e-12 47.4 13.3 9.8e-10 37.6 0.0 3.7 3 1 0 3 3 3 2 COG4 transport protein Pkinase PF00069.20 EEA06707.1 - 1e-60 205.1 0.0 1.6e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06707.1 - 2e-34 118.8 0.0 3.4e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA06707.1 - 6.3e-09 35.2 0.0 6.5e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA06707.1 - 0.037 13.7 0.0 0.44 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSBP1 PF06825.7 EEA06708.1 - 8e-14 50.9 4.2 1.6e-13 50.0 2.9 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.4 EEA06708.1 - 0.00027 21.0 3.7 0.0004 20.4 2.4 1.4 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 EEA06708.1 - 0.003 16.1 0.6 0.0032 16.0 0.4 1.2 1 0 0 1 1 1 1 Tektin family Laminin_II PF06009.7 EEA06708.1 - 0.005 16.5 0.8 0.0062 16.2 0.6 1.3 1 0 0 1 1 1 1 Laminin Domain II EzrA PF06160.7 EEA06708.1 - 0.0062 14.7 0.1 0.0064 14.7 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA COG5 PF10392.4 EEA06708.1 - 0.01 15.7 2.4 0.9 9.5 0.1 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EEA06708.1 - 0.01 15.6 2.1 0.013 15.3 1.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hormone_1 PF00103.15 EEA06708.1 - 0.015 14.6 1.1 0.016 14.5 0.8 1.2 1 0 0 1 1 1 0 Somatotropin hormone family DUF1664 PF07889.7 EEA06708.1 - 0.022 14.5 1.5 0.027 14.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) BMFP PF04380.8 EEA06708.1 - 0.05 13.7 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity LOH1CR12 PF10158.4 EEA06708.1 - 0.068 12.9 0.7 0.081 12.7 0.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein DUF848 PF05852.6 EEA06708.1 - 0.081 12.7 1.2 0.11 12.3 0.7 1.2 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 EEA06708.1 - 0.084 13.1 2.5 0.19 12.0 1.4 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.7 EEA06708.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF3086 PF11285.3 EEA06708.1 - 0.098 11.4 0.4 0.11 11.3 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) FlaC_arch PF05377.6 EEA06708.1 - 0.11 12.3 2.2 2.8 7.9 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 EEA06708.1 - 0.12 12.5 4.9 0.25 11.5 3.4 1.7 1 1 0 1 1 1 0 Syntaxin Prominin PF05478.6 EEA06708.1 - 0.81 7.1 5.8 0.84 7.0 4.0 1.0 1 0 0 1 1 1 0 Prominin Cyclin PF08613.6 EEA06709.1 - 8.5e-30 104.1 1.7 2.4e-29 102.6 1.2 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA06709.1 - 8.9e-09 34.9 0.2 1.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Myosin_head PF00063.16 EEA06710.1 - 1.1e-173 579.0 2.4 1.9e-173 578.2 1.6 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) DEAD PF00270.24 EEA06710.1 - 0.0013 18.2 0.3 0.51 9.8 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA06710.1 - 0.0034 17.5 0.0 0.025 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EEA06710.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EEA06710.1 - 0.035 13.2 0.0 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EEA06710.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EEA06710.1 - 0.1 12.8 0.5 1.3 9.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Rho_N PF07498.7 EEA06714.1 - 0.27 11.0 1.7 0.43 10.3 0.2 2.1 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain FAM180 PF15173.1 EEA06717.1 - 0.053 13.3 0.3 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 FAM180 family Sec63 PF02889.11 EEA06721.1 - 7.8e-33 114.0 0.1 1.2e-32 113.4 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EEA06721.1 - 2.8e-22 78.2 0.5 7.1e-22 76.9 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain BatA PF07584.6 EEA06721.1 - 0.41 10.8 4.0 0.25 11.5 0.4 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Pkinase PF00069.20 EEA06723.1 - 2.1e-72 243.4 0.0 2.5e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06723.1 - 2.7e-38 131.5 0.0 3.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA06723.1 - 7.1e-06 25.1 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA06723.1 - 5.4e-05 22.3 0.0 7.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA06723.1 - 0.0013 18.5 0.2 0.066 12.9 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1474 PF07342.6 EEA06724.1 - 0.086 13.0 3.3 0.4 10.9 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) DUF4404 PF14357.1 EEA06724.1 - 0.1 13.0 2.6 0.36 11.2 1.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF1664 PF07889.7 EEA06724.1 - 0.18 11.5 4.4 0.2 11.4 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SNARE PF05739.14 EEA06724.1 - 0.2 11.3 3.3 0.15 11.7 0.5 2.1 2 0 0 2 2 2 0 SNARE domain Seryl_tRNA_N PF02403.17 EEA06724.1 - 0.61 10.1 7.3 2.2 8.3 2.6 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.4 EEA06724.1 - 0.8 9.9 4.3 2 8.6 0.5 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AKNA PF12443.3 EEA06724.1 - 2.4 8.2 8.2 1.5 8.9 3.1 2.4 2 1 1 3 3 3 0 AT-hook-containing transcription factor FlxA PF14282.1 EEA06724.1 - 4.8 7.1 8.4 19 5.2 2.3 2.8 2 1 0 2 2 2 0 FlxA-like protein MSC PF09402.5 EEA06725.1 - 4.3e-22 78.2 9.2 9.2e-22 77.1 6.4 1.6 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain Fer2_3 PF13085.1 EEA06726.1 - 7.1e-30 103.0 0.0 2e-29 101.6 0.0 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EEA06726.1 - 3.3e-10 40.1 5.0 3.3e-10 40.1 3.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEA06726.1 - 1.7e-08 34.3 3.4 1.7e-08 34.3 2.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEA06726.1 - 1.5e-05 25.1 2.6 0.06 13.6 0.2 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEA06726.1 - 1.5e-05 25.3 4.6 0.00011 22.5 0.4 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EEA06726.1 - 0.00089 19.5 2.8 0.00089 19.5 1.9 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EEA06726.1 - 0.0029 17.3 0.4 0.0029 17.3 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 EEA06726.1 - 0.005 16.6 7.1 0.005 16.6 4.9 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEA06726.1 - 1.2 9.1 15.7 1.6 8.8 3.0 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain MMtag PF10159.4 EEA06727.1 - 2.5e-14 53.0 0.9 1.6e-13 50.4 0.7 2.3 1 1 0 1 1 1 1 Kinase phosphorylation protein ThiF PF00899.16 EEA06728.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family HNOB PF07700.10 EEA06728.1 - 0.098 12.1 0.5 12 5.3 0.0 2.4 3 0 0 3 3 3 0 Heme NO binding DEAD PF00270.24 EEA06729.1 - 4.8e-39 133.5 0.1 2.2e-38 131.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06729.1 - 3.1e-28 97.4 0.2 7.2e-28 96.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEA06729.1 - 4.3e-05 23.1 1.7 0.00088 18.9 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 EEA06729.1 - 0.0083 16.2 0.1 0.032 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF1253 PF06862.7 EEA06729.1 - 0.015 13.7 0.0 0.038 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 EEA06729.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA06729.1 - 0.026 13.5 0.1 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.11 EEA06729.1 - 0.07 12.3 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EEA06729.1 - 0.18 11.3 0.0 0.67 9.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain FF PF01846.14 EEA06730.1 - 2.3e-05 24.2 5.8 2.6e-05 24.0 0.1 3.6 3 0 0 3 3 3 1 FF domain WD40 PF00400.27 EEA06731.1 - 1.7e-47 157.6 9.6 1.4e-10 40.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA06731.1 - 0.00071 17.8 0.8 0.11 10.6 0.1 3.6 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEA06731.1 - 0.0059 15.3 2.8 0.92 8.1 0.4 3.2 2 1 0 2 2 2 1 Nup133 N terminal like Ricin_B_lectin PF00652.17 EEA06731.1 - 0.014 15.4 0.3 0.27 11.2 0.0 2.6 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain PQQ_2 PF13360.1 EEA06731.1 - 0.015 14.7 0.0 0.05 13.0 0.0 1.9 3 0 0 3 3 3 0 PQQ-like domain 7TM_GPCR_Sri PF10327.4 EEA06731.1 - 0.21 10.4 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Alba PF01918.16 EEA06732.1 - 0.00031 20.2 0.3 0.00046 19.7 0.2 1.3 1 0 0 1 1 1 1 Alba Peptidase_M9_N PF08453.5 EEA06732.1 - 0.037 13.3 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M9 N-terminal LSM PF01423.17 EEA06733.1 - 4.9e-17 61.2 1.7 5.8e-17 60.9 1.2 1.1 1 0 0 1 1 1 1 LSM domain OTU PF02338.14 EEA06734.1 - 2.2e-18 66.9 1.1 5.1e-18 65.8 0.8 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEA06734.1 - 3.1e-08 33.2 1.9 0.0041 16.5 0.3 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain PX PF00787.19 EEA06735.1 - 5.4e-15 55.1 0.1 1.2e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 EEA06735.1 - 0.0036 17.1 1.2 0.9 9.5 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3639 PF12341.3 EEA06735.1 - 0.018 15.0 0.2 0.036 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Atg8 PF02991.11 EEA06736.1 - 4.7e-32 110.0 1.4 1e-30 105.7 1.0 2.0 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEA06736.1 - 0.00042 20.4 0.6 0.0042 17.2 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Asp_Glu_race_2 PF14669.1 EEA06737.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative aspartate racemase DUF3091 PF11291.3 EEA06737.1 - 1.7 8.6 10.9 0.1 12.5 1.6 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF3091) RCC1 PF00415.13 EEA06738.1 - 7.2e-10 38.9 0.1 7.3e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA06738.1 - 1.7e-06 27.4 3.9 4e-05 23.0 0.1 3.2 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Rab5-bind PF09311.6 EEA06738.1 - 0.01 15.7 6.9 0.01 15.7 4.8 4.3 2 1 2 4 4 4 0 Rabaptin-like protein DUF606 PF04657.8 EEA06741.1 - 0.029 14.4 0.3 0.033 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 FecCD PF01032.13 EEA06741.1 - 0.052 12.3 1.9 0.062 12.1 1.4 1.0 1 0 0 1 1 1 0 FecCD transport family Rab5ip PF07019.7 EEA06741.1 - 0.058 13.5 0.2 0.078 13.1 0.1 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) PLDc_N PF13396.1 EEA06741.1 - 0.072 12.7 0.6 0.072 12.7 0.4 2.2 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal Ribosomal_L38e PF01781.13 EEA06742.1 - 8.8e-31 105.4 1.7 1e-30 105.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family TPR_2 PF07719.12 EEA06743.1 - 2.3e-16 58.2 10.8 0.00076 19.2 0.3 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat SRP72 PF08492.7 EEA06743.1 - 3.2e-14 53.0 2.7 3.2e-14 53.0 1.9 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_1 PF00515.23 EEA06743.1 - 1.9e-12 46.1 18.3 0.013 15.0 0.9 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEA06743.1 - 6e-12 45.0 14.9 0.084 12.5 0.0 6.6 6 1 0 6 6 6 5 TPR repeat Apc3 PF12895.2 EEA06743.1 - 1.5e-10 41.0 28.2 7e-07 29.2 1.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEA06743.1 - 7.2e-08 32.2 10.7 0.092 12.6 0.4 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06743.1 - 5.5e-06 25.7 12.3 0.087 12.6 0.6 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA06743.1 - 9.8e-06 25.3 0.1 0.0017 18.1 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06743.1 - 3.2e-05 24.1 1.4 14 6.1 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06743.1 - 4.4e-05 22.9 0.1 1.9 8.4 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06743.1 - 5.3e-05 23.7 0.1 0.41 11.3 0.0 4.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06743.1 - 9.1e-05 22.3 0.3 5.5 7.4 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06743.1 - 0.00041 20.6 1.3 45 4.8 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEA06743.1 - 0.019 14.7 6.0 0.11 12.3 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA06743.1 - 0.11 12.4 0.1 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EEA06743.1 - 0.16 11.8 2.0 22 4.9 0.2 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ArsA_ATPase PF02374.10 EEA06744.1 - 1.2e-92 310.1 0.0 1.6e-83 280.2 0.0 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EEA06744.1 - 1.8e-13 50.3 0.0 3.9e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA06744.1 - 5.1e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EEA06744.1 - 5.3e-05 22.5 0.0 8.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EEA06744.1 - 0.0013 18.2 0.0 0.0036 16.7 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EEA06744.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EEA06744.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EEA06744.1 - 0.041 13.3 0.1 0.054 12.9 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EEA06744.1 - 0.041 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EEA06744.1 - 0.051 12.9 0.1 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA06744.1 - 0.13 13.0 0.0 0.57 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEA06744.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 EEA06745.1 - 5.6e-51 170.5 0.0 5e-28 96.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA06745.1 - 4.8e-11 42.7 0.2 4.7e-06 26.5 0.1 2.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA06745.1 - 4.2e-10 39.6 0.6 0.00023 21.1 0.0 4.4 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA06745.1 - 1.8e-08 34.5 1.1 0.023 14.9 0.1 4.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEA06745.1 - 1.4e-07 31.4 0.0 0.0032 17.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EEA06745.1 - 1.2e-05 24.9 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 EEA06745.1 - 0.00027 20.9 1.3 0.26 11.2 0.1 3.1 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 EEA06745.1 - 0.00036 20.1 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EEA06745.1 - 0.00036 20.0 0.3 1.3 8.5 0.0 2.8 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EEA06745.1 - 0.012 15.4 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain DSBA PF01323.15 EEA06745.1 - 0.13 11.7 0.1 4.9 6.6 0.0 2.6 2 1 1 3 3 3 0 DSBA-like thioredoxin domain DUF2897 PF11446.3 EEA06745.1 - 1.4 8.8 5.1 2.7 7.8 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) CLASP_N PF12348.3 EEA06746.1 - 4.5e-07 29.4 2.2 1.6e-06 27.6 1.6 2.0 1 1 0 1 1 1 1 CLASP N terminal RINGv PF12906.2 EEA06747.1 - 2.5e-11 43.4 3.0 2.5e-11 43.4 2.1 2.3 2 0 0 2 2 2 1 RING-variant domain FHA PF00498.21 EEA06747.1 - 6.4e-06 26.1 1.7 0.00014 21.9 0.1 3.2 3 0 0 3 3 3 1 FHA domain BING4CT PF08149.6 EEA06748.1 - 1e-35 121.1 0.0 1.1e-32 111.3 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EEA06748.1 - 2.2e-07 30.4 2.7 0.0038 17.0 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 EEA06749.1 - 0.0044 17.3 1.1 0.63 10.4 0.0 2.9 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Nol1_Nop2_Fmu PF01189.12 EEA06750.1 - 2.7e-11 43.3 0.0 9.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family WD40 PF00400.27 EEA06751.1 - 7.3e-28 95.4 10.7 3.1e-08 33.1 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA06751.1 - 1.7e-06 27.8 0.0 0.00052 19.7 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EEA06751.1 - 0.027 12.2 0.0 2.7 5.6 0.0 2.3 3 0 0 3 3 3 0 IKI3 family PP2C PF00481.16 EEA06752.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA06752.1 - 0.00022 20.6 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Glycos_transf_2 PF00535.21 EEA06753.1 - 1e-20 74.1 0.0 1.8e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 EEA06753.1 - 2.4e-12 46.9 6.2 1.1e-07 31.8 1.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 EEA06753.1 - 1.4e-07 30.8 0.1 8.4e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 EEA06753.1 - 2.1e-07 31.0 0.0 9.3e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEA06753.1 - 4.6e-05 22.6 0.0 0.00016 20.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 EEA06753.1 - 0.0081 16.5 0.4 0.067 13.5 0.3 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like GlcNAc PF11397.3 EEA06753.1 - 0.0092 15.1 0.1 0.06 12.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) TRP PF06011.7 EEA06753.1 - 0.036 12.6 0.1 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel zf-RING_2 PF13639.1 EEA06754.1 - 2.2e-14 52.9 5.8 4e-14 52.1 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA06754.1 - 2.9e-07 30.3 6.5 5.6e-07 29.4 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA06754.1 - 7.7e-07 29.1 3.2 1.8e-06 27.9 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA06754.1 - 9.8e-07 28.4 4.2 1.7e-06 27.6 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA06754.1 - 3.1e-06 26.7 4.7 9.1e-06 25.2 3.2 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA06754.1 - 0.00023 20.7 6.1 0.00048 19.7 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA06754.1 - 0.00046 19.9 0.8 0.00046 19.9 0.6 2.0 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EEA06754.1 - 0.0045 17.0 5.3 0.0088 16.0 3.7 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EEA06754.1 - 0.022 14.7 4.9 0.092 12.7 3.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEA06754.1 - 0.024 14.2 6.6 0.048 13.2 4.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEA06754.1 - 0.083 12.6 2.5 0.12 12.1 0.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_RING PF05883.6 EEA06754.1 - 0.34 10.7 5.2 0.39 10.5 2.8 1.6 1 1 1 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 EEA06754.1 - 4 7.5 6.2 13 5.9 4.3 1.9 1 1 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.1 EEA06754.1 - 5.3 6.6 7.5 16 5.1 3.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Clat_adaptor_s PF01217.15 EEA06755.1 - 1e-12 48.0 1.7 1.3e-12 47.6 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain E1-E2_ATPase PF00122.15 EEA06756.1 - 2.5e-67 226.2 2.8 2.5e-67 226.2 1.9 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA06756.1 - 3.6e-49 166.7 6.5 3.6e-49 166.7 4.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA06756.1 - 6.4e-31 108.4 0.0 9.2e-30 104.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA06756.1 - 1.3e-17 63.4 2.0 2.3e-17 62.7 0.1 2.4 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEA06756.1 - 1.4e-15 57.9 0.0 4.5e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA06756.1 - 6.1e-14 51.2 0.0 2e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA06756.1 - 0.0002 21.0 1.3 0.0064 16.1 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNA_pol_Rpb4 PF03874.11 EEA06757.1 - 1.6e-15 57.1 0.4 1.9e-15 56.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 SecE PF00584.15 EEA06758.1 - 7.9e-11 41.3 0.0 9.7e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Cpn60_TCP1 PF00118.19 EEA06759.1 - 4.8e-150 500.3 1.5 5.4e-150 500.2 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Band_7 PF01145.20 EEA06761.1 - 3.9e-29 101.8 0.9 6.1e-29 101.1 0.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EEA06761.1 - 6.9e-05 21.9 0.5 9.3e-05 21.4 0.3 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3811 PF11656.3 EEA06761.1 - 0.2 11.7 1.2 0.3 11.1 0.2 1.7 2 0 0 2 2 2 0 YjbD family (DUF3811) NIF PF03031.13 EEA06762.1 - 4.1e-22 78.5 0.0 7.5e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEA06762.1 - 9.7e-08 31.7 0.3 5.2e-07 29.4 0.2 2.2 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEA06762.1 - 7.1e-07 29.2 1.8 3.7e-06 27.0 0.4 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.1 EEA06762.1 - 0.0085 16.3 0.0 0.041 14.1 0.0 2.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.17 EEA06764.1 - 1.1e-44 152.3 0.0 1.7e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SMN PF06003.7 EEA06765.1 - 2.9e-06 26.5 0.1 5.2e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) Paf1 PF03985.8 EEA06766.1 - 0.56 8.8 8.3 0.83 8.3 5.8 1.2 1 0 0 1 1 1 0 Paf1 DUF3159 PF11361.3 EEA06767.1 - 0.026 13.9 0.2 0.33 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3159) zf-C2H2_4 PF13894.1 EEA06768.1 - 0.013 15.7 0.2 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Cor1 PF04803.7 EEA06768.1 - 0.14 11.9 3.9 5.2 6.8 0.3 2.6 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region CAP PF00188.21 EEA06769.1 - 3.1e-53 179.5 5.2 2.6e-15 57.0 0.0 4.5 4 0 0 4 4 4 4 Cysteine-rich secretory protein family Myosin_head PF00063.16 EEA06774.1 - 2.5e-165 551.3 18.1 4.7e-165 550.4 12.5 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.13 EEA06774.1 - 2e-31 107.9 5.0 9e-09 35.4 0.0 7.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA06774.1 - 2.8e-29 100.0 11.8 3.2e-08 32.9 0.4 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EEA06774.1 - 4.3e-12 44.5 36.7 0.00078 18.8 0.1 7.0 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EEA06774.1 - 0.00095 19.3 0.0 0.0046 17.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EEA06774.1 - 0.018 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EEA06774.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EEA06774.1 - 0.025 14.3 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EEA06774.1 - 0.03 13.4 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEA06774.1 - 0.098 13.4 2.9 0.17 12.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain Glutaredoxin PF00462.19 EEA06775.1 - 0.00015 21.6 0.8 0.0032 17.4 0.0 2.9 3 1 0 3 3 3 1 Glutaredoxin DZR PF12773.2 EEA06775.1 - 0.028 14.2 0.9 0.054 13.3 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EEA06775.1 - 0.33 11.0 1.2 0.69 9.9 0.9 1.6 1 0 0 1 1 1 0 zinc-finger zf-ribbon_3 PF13248.1 EEA06775.1 - 0.41 9.9 2.2 0.76 9.0 1.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RNA_pol_L_2 PF13656.1 EEA06776.1 - 1.8e-23 81.7 0.1 2.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEA06776.1 - 1.3e-08 33.8 0.0 8.1e-08 31.2 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ras PF00071.17 EEA06777.1 - 1.6e-50 170.6 0.0 1.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA06777.1 - 9.2e-17 61.6 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA06777.1 - 1.4e-13 50.4 0.0 1.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA06777.1 - 1e-05 24.8 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA06777.1 - 7.9e-05 22.1 0.1 0.00034 20.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA06777.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEA06777.1 - 0.0098 15.1 0.0 0.028 13.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEA06777.1 - 0.021 14.9 0.0 0.071 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain Nudc_N PF14050.1 EEA06778.1 - 3.2e-18 65.4 0.8 6.2e-18 64.5 0.6 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 EEA06778.1 - 5.4e-16 58.9 3.2 1.3e-15 57.7 2.2 1.7 1 0 0 1 1 1 1 CS domain DUF3698 PF12479.3 EEA06778.1 - 0.0071 16.4 3.3 0.084 12.9 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3698) ATP-grasp_3 PF02655.9 EEA06778.1 - 0.093 12.5 0.7 0.26 11.1 0.0 2.1 3 0 0 3 3 3 0 ATP-grasp domain DUF1900 PF08954.6 EEA06779.1 - 8.1e-45 151.6 0.0 1.8e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EEA06779.1 - 9.2e-29 98.2 1.2 1e-10 41.0 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 EEA06779.1 - 2.7e-06 26.9 0.1 5.1e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nup160 PF11715.3 EEA06779.1 - 0.035 12.2 0.1 0.35 8.9 0.1 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PSII_BNR PF14870.1 EEA06779.1 - 0.044 12.7 0.4 0.063 12.2 0.3 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 DUF1115 PF06544.7 EEA06780.1 - 7.2e-20 70.9 1.0 2.2e-19 69.3 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) DUF4515 PF14988.1 EEA06780.1 - 0.041 13.5 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Sin3_corepress PF08295.7 EEA06780.1 - 0.31 10.8 3.6 0.81 9.4 2.4 1.7 1 1 0 1 1 1 0 Sin3 family co-repressor RWD PF05773.17 EEA06780.1 - 0.38 10.6 2.5 0.5 10.2 0.5 2.2 1 1 0 2 2 2 0 RWD domain Metallophos PF00149.23 EEA06781.1 - 1.1e-15 57.5 3.9 2.9e-15 56.1 2.7 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA06781.1 - 2e-05 24.4 0.0 5.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glycos_transf_2 PF00535.21 EEA06782.1 - 1.3e-08 34.6 0.1 3.2e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEA06782.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEA06782.1 - 0.00032 19.8 0.1 0.0006 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Latarcin PF10279.4 EEA06782.1 - 0.72 10.0 2.9 3.2 8.0 1.1 2.4 2 1 0 2 2 2 0 Latarcin precursor EF1G PF00647.14 EEA06783.1 - 1.6e-37 127.4 0.0 3.1e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EEA06783.1 - 4e-05 23.5 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA06783.1 - 0.0017 18.8 0.0 0.0047 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA06783.1 - 0.0075 16.1 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_L6e PF01159.14 EEA06784.1 - 1.2e-35 122.0 0.1 1.7e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e DSPn PF14671.1 EEA06785.1 - 1.2e-46 158.1 0.3 1.2e-46 158.1 0.2 2.6 4 0 0 4 4 4 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EEA06785.1 - 2.7e-18 65.8 0.0 7e-11 41.8 0.0 2.6 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA06785.1 - 3.5e-06 26.5 0.1 0.00029 20.2 0.0 2.6 2 1 1 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEA06785.1 - 0.00025 21.3 0.4 0.052 13.7 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEA06785.1 - 0.00038 20.5 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate RRM_1 PF00076.17 EEA06786.1 - 1.3e-32 111.2 1.4 8.5e-18 63.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06786.1 - 1.8e-27 95.1 0.4 3.6e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06786.1 - 1.4e-13 50.4 0.7 1.6e-06 27.8 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_2 PF00891.13 EEA06786.1 - 0.0022 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ribosomal_L33 PF00471.15 EEA06787.1 - 0.49 10.6 2.2 1.6 9.0 1.5 2.1 1 1 0 1 1 1 0 Ribosomal protein L33 ABC_tran PF00005.22 EEA06791.1 - 3.3e-52 176.4 0.0 6.9e-30 104.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA06791.1 - 3.6e-39 134.8 28.5 7.8e-28 97.6 4.3 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEA06791.1 - 8.4e-10 38.2 1.8 0.0022 17.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA06791.1 - 6.9e-07 28.7 0.6 0.0079 15.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA06791.1 - 0.00049 20.0 0.2 0.15 12.0 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EEA06791.1 - 0.0027 18.2 1.0 1.6 9.2 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EEA06791.1 - 0.0037 17.6 3.7 1.4 9.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EEA06791.1 - 0.0046 16.3 0.0 0.92 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA06791.1 - 0.091 12.7 2.9 0.43 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 EEA06791.1 - 0.096 12.1 0.2 13 5.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EEA06791.1 - 0.11 12.0 0.1 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EEA06791.1 - 0.14 11.6 3.4 0.11 11.9 0.1 2.3 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2207 PF09972.4 EEA06791.1 - 0.16 10.5 6.6 0.017 13.7 0.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF258 PF03193.11 EEA06791.1 - 0.21 10.7 0.7 14 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EEA06791.1 - 0.38 10.5 0.9 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 EEA06791.1 - 0.42 10.3 6.4 0.35 10.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 EEA06792.1 - 1.2e-52 177.9 0.0 2.5e-32 112.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA06792.1 - 2.3e-34 119.0 38.6 9.4e-21 74.4 10.8 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EEA06792.1 - 9.9e-12 44.5 7.6 0.0018 17.5 0.1 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA06792.1 - 3.8e-06 26.3 0.5 0.042 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEA06792.1 - 0.0013 19.5 0.1 0.64 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEA06792.1 - 0.003 17.4 0.1 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEA06792.1 - 0.017 15.5 1.5 2.1 8.8 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_18 PF13238.1 EEA06792.1 - 0.028 14.7 1.6 0.36 11.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EEA06792.1 - 0.031 14.0 2.7 0.055 13.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EEA06792.1 - 0.072 12.4 0.6 12 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEA06792.1 - 0.55 10.1 1.2 25 4.7 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain ubiquitin PF00240.18 EEA06795.1 - 1.2e-23 82.3 0.8 1.3e-23 82.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA06795.1 - 9e-15 54.1 0.9 9.9e-15 53.9 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA06795.1 - 4.1e-05 23.7 0.3 0.0001 22.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEA06795.1 - 0.0009 19.1 0.1 0.0019 18.0 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EEA06795.1 - 0.03 13.9 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing TUG-UBL1 PF11470.3 EEA06795.1 - 0.078 12.9 0.2 0.28 11.1 0.0 1.8 1 1 1 2 2 2 0 GLUT4 regulating protein TUG Big_5 PF13205.1 EEA06796.1 - 2.1e-08 34.7 0.0 8.3e-05 23.1 0.0 3.2 2 1 0 2 2 2 2 Bacterial Ig-like domain Toluene_X PF03349.11 EEA06796.1 - 0.53 8.5 0.0 0.85 7.9 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Snf7 PF03357.16 EEA06797.1 - 5.2e-16 58.4 14.4 5.2e-16 58.4 10.0 1.3 1 1 0 1 1 1 1 Snf7 ATP-synt_D PF01813.12 EEA06797.1 - 9.1e-05 22.0 3.5 9.1e-05 22.0 2.4 1.6 2 0 0 2 2 2 1 ATP synthase subunit D YlqD PF11068.3 EEA06797.1 - 0.0087 16.0 6.2 0.0087 16.0 4.3 2.7 1 1 2 3 3 3 1 YlqD protein Mitofilin PF09731.4 EEA06797.1 - 0.17 10.4 16.2 0.52 8.9 11.3 1.6 1 1 0 1 1 1 0 Mitochondrial inner membrane protein DUF1451 PF07295.6 EEA06797.1 - 9.2 6.0 8.9 1.9 8.2 3.0 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) LSM PF01423.17 EEA06798.1 - 6.8e-17 60.7 0.6 1.3e-16 59.9 0.4 1.5 1 1 0 1 1 1 1 LSM domain Methyltrn_RNA_3 PF02598.12 EEA06799.1 - 1.8e-80 270.4 0.0 2.2e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase DEAD PF00270.24 EEA06800.1 - 2.9e-36 124.5 0.0 8.2e-34 116.5 0.0 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA06800.1 - 1.7e-27 95.0 0.0 5.5e-27 93.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA06800.1 - 8.3e-06 25.7 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EEA06800.1 - 0.00013 20.5 0.0 0.19 10.1 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 EEA06800.1 - 0.002 17.4 0.0 0.0053 16.0 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain Helicase_C_2 PF13307.1 EEA06800.1 - 0.048 13.6 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain Cyclin_N PF00134.18 EEA06801.1 - 3.9e-07 29.6 0.1 1.1e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Rep_fac-A_C PF08646.5 EEA06802.1 - 2.1e-40 137.7 0.7 1.6e-38 131.6 0.1 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EEA06802.1 - 5.8e-13 48.5 0.6 2.6e-10 39.9 0.1 3.6 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EEA06802.1 - 3.3e-05 23.8 0.1 0.00013 22.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF223 Sgf11 PF08209.6 EEA06802.1 - 0.11 11.8 1.6 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Prefoldin_2 PF01920.15 EEA06803.1 - 8.3e-21 73.7 9.4 1e-20 73.4 6.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EEA06803.1 - 0.00012 21.8 6.9 0.00022 20.9 4.8 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4600 PF15372.1 EEA06803.1 - 0.00049 20.3 5.3 0.00082 19.5 3.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4600) Laminin_I PF06008.9 EEA06803.1 - 0.00086 18.7 5.8 0.088 12.1 0.6 2.0 1 1 1 2 2 2 2 Laminin Domain I GAS PF13851.1 EEA06803.1 - 0.00087 18.5 5.6 0.025 13.7 0.3 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EEA06803.1 - 0.00094 17.9 5.9 0.077 11.6 0.7 2.0 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF4140 PF13600.1 EEA06803.1 - 0.0015 18.9 0.8 0.34 11.3 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EEA06803.1 - 0.0022 17.4 4.1 0.37 10.3 0.1 2.2 2 0 0 2 2 2 2 Septum formation initiator ATP-synt_D PF01813.12 EEA06803.1 - 0.0037 16.8 2.1 0.18 11.3 0.1 2.0 2 0 0 2 2 2 1 ATP synthase subunit D TMF_DNA_bd PF12329.3 EEA06803.1 - 0.0046 16.7 12.9 0.13 12.0 1.8 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF816 PF05674.7 EEA06803.1 - 0.0049 16.6 0.4 0.0091 15.7 0.2 1.5 1 1 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) FlxA PF14282.1 EEA06803.1 - 0.006 16.5 8.6 0.13 12.2 0.9 2.2 2 0 0 2 2 2 1 FlxA-like protein SlyX PF04102.7 EEA06803.1 - 0.0066 16.7 1.8 2 8.8 0.2 2.2 2 0 0 2 2 2 0 SlyX Prefoldin PF02996.12 EEA06803.1 - 0.0098 15.5 1.6 0.0098 15.5 1.1 2.1 1 1 1 2 2 2 1 Prefoldin subunit Fib_alpha PF08702.5 EEA06803.1 - 0.01 15.9 5.1 0.017 15.2 3.5 1.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Med4 PF10018.4 EEA06803.1 - 0.011 15.0 5.2 0.039 13.3 0.5 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec8_exocyst PF04048.9 EEA06803.1 - 0.012 15.3 1.3 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HJURP_C PF12347.3 EEA06803.1 - 0.012 15.2 1.3 0.012 15.1 0.1 1.7 2 0 0 2 2 1 0 Holliday junction regulator protein family C-terminal repeat TMF_TATA_bd PF12325.3 EEA06803.1 - 0.012 15.3 5.1 0.11 12.2 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HAUS4 PF14735.1 EEA06803.1 - 0.013 14.8 3.8 1.3 8.2 0.2 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 PhoU PF01895.14 EEA06803.1 - 0.016 15.6 1.5 0.51 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoU domain DUF2130 PF09903.4 EEA06803.1 - 0.018 13.7 3.8 0.3 9.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) FliD_C PF07195.7 EEA06803.1 - 0.026 13.8 2.2 0.13 11.5 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Tropomyosin_1 PF12718.2 EEA06803.1 - 0.027 14.3 8.4 0.27 11.0 1.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Ax_dynein_light PF10211.4 EEA06803.1 - 0.03 14.1 5.2 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain MIS13 PF08202.6 EEA06803.1 - 0.033 13.2 3.1 0.04 12.9 2.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family ORF6C PF10552.4 EEA06803.1 - 0.041 13.6 2.7 0.95 9.2 0.3 2.2 2 0 0 2 2 2 0 ORF6C domain DUF4200 PF13863.1 EEA06803.1 - 0.047 13.6 7.7 0.36 10.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EEA06803.1 - 0.053 13.0 6.5 0.99 8.9 0.8 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Occludin_ELL PF07303.8 EEA06803.1 - 0.055 14.1 3.2 0.58 10.9 0.2 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF1041 PF06292.12 EEA06803.1 - 0.056 13.6 0.9 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) FliJ PF02050.11 EEA06803.1 - 0.058 13.4 3.3 4.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein STAT_alpha PF01017.15 EEA06803.1 - 0.062 13.0 4.2 0.12 12.1 2.9 1.4 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF615 PF04751.9 EEA06803.1 - 0.069 12.7 0.4 0.096 12.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF615) DUF724 PF05266.9 EEA06803.1 - 0.074 12.6 7.1 0.21 11.1 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) PEP-utilisers_N PF05524.8 EEA06803.1 - 0.077 12.7 0.3 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Snf7 PF03357.16 EEA06803.1 - 0.077 12.3 5.3 0.16 11.3 0.3 2.0 2 0 0 2 2 2 0 Snf7 XhlA PF10779.4 EEA06803.1 - 0.079 12.8 4.3 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF972 PF06156.8 EEA06803.1 - 0.09 13.1 2.9 2.9 8.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2802 PF10975.3 EEA06803.1 - 0.098 12.4 1.6 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Jnk-SapK_ap_N PF09744.4 EEA06803.1 - 0.11 12.4 4.9 2.5 8.0 0.4 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Lectin_N PF03954.9 EEA06803.1 - 0.12 11.7 0.5 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Myosin_tail_1 PF01576.14 EEA06803.1 - 0.12 10.0 9.1 0.11 10.1 0.8 2.0 2 0 0 2 2 2 0 Myosin tail TACC PF05010.9 EEA06803.1 - 0.14 11.9 5.1 0.24 11.1 3.5 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) IncA PF04156.9 EEA06803.1 - 0.15 11.6 9.6 0.64 9.5 6.7 1.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 EEA06803.1 - 0.15 11.9 5.0 1.7 8.5 0.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MutS_IV PF05190.13 EEA06803.1 - 0.16 12.2 3.1 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 MutS family domain IV ATG16 PF08614.6 EEA06803.1 - 0.16 11.8 4.8 3.5 7.3 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Vps5 PF09325.5 EEA06803.1 - 0.16 11.1 5.9 0.89 8.7 0.3 2.1 1 1 0 2 2 2 0 Vps5 C terminal like HAUS-augmin3 PF14932.1 EEA06803.1 - 0.16 11.0 6.5 1.3 8.1 4.6 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 EEA06803.1 - 0.17 10.9 9.4 0.19 10.7 4.4 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 EEA06803.1 - 0.18 9.1 5.0 0.22 8.7 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EEA06803.1 - 0.2 11.5 9.4 0.62 9.9 0.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EEA06803.1 - 0.2 10.0 7.9 0.41 9.0 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Mod_r PF07200.8 EEA06803.1 - 0.2 11.5 5.5 0.14 12.0 2.3 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Syntaxin-6_N PF09177.6 EEA06803.1 - 0.24 11.7 6.7 0.4 11.1 0.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3086 PF11285.3 EEA06803.1 - 0.25 10.1 2.2 0.2 10.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) AAA_23 PF13476.1 EEA06803.1 - 0.25 11.6 4.8 0.35 11.1 3.3 1.2 1 0 0 1 1 1 0 AAA domain PCRF PF03462.13 EEA06803.1 - 0.27 10.9 3.8 4.1 7.1 0.4 2.1 2 0 0 2 2 2 0 PCRF domain NPV_P10 PF05531.7 EEA06803.1 - 0.27 11.4 2.1 13 6.1 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EEA06803.1 - 0.29 11.3 5.0 3.7 7.7 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.14 EEA06803.1 - 0.33 10.4 7.1 0.42 10.1 0.7 2.1 2 0 0 2 2 2 0 GrpE DASH_Dad3 PF08656.5 EEA06803.1 - 0.34 10.6 3.4 2.4 7.9 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 End3 PF12761.2 EEA06803.1 - 0.35 10.4 7.7 4.9 6.7 5.4 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ACCA PF03255.9 EEA06803.1 - 0.36 10.3 3.4 1.7 8.2 0.3 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_GP20 PF06810.6 EEA06803.1 - 0.38 10.1 8.5 0.42 10.0 0.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4618 PF15397.1 EEA06803.1 - 0.42 9.8 8.4 2.3 7.4 5.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF948 PF06103.6 EEA06803.1 - 0.48 10.3 5.1 0.68 9.8 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.6 EEA06803.1 - 0.51 10.1 4.2 8.5 6.1 0.3 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mnd1 PF03962.10 EEA06803.1 - 0.53 9.9 6.7 2.1 7.9 4.6 1.8 1 1 0 1 1 1 0 Mnd1 family DUF3091 PF11291.3 EEA06803.1 - 0.61 10.0 4.7 1 9.3 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) AAA_13 PF13166.1 EEA06803.1 - 0.68 8.3 8.7 3 6.1 6.1 1.7 1 1 0 1 1 1 0 AAA domain YlqD PF11068.3 EEA06803.1 - 0.72 9.8 6.8 0.38 10.7 0.5 2.1 1 1 0 2 2 2 0 YlqD protein Uds1 PF15456.1 EEA06803.1 - 0.8 9.6 6.9 3 7.8 4.3 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Lge1 PF11488.3 EEA06803.1 - 0.86 9.8 7.2 1.4 9.2 1.0 2.3 1 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Seryl_tRNA_N PF02403.17 EEA06803.1 - 0.89 9.5 10.9 2.1e+02 1.9 7.5 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.6 EEA06803.1 - 0.91 9.5 7.1 1.1 9.2 1.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.16 EEA06803.1 - 1.1 9.3 10.8 1.7 8.6 1.5 2.5 2 1 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.6 EEA06803.1 - 1.2 8.8 10.4 1.5 8.5 1.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3847 PF12958.2 EEA06803.1 - 1.3 8.8 9.7 2 8.2 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF3573 PF12097.3 EEA06803.1 - 1.5 7.3 7.3 0.88 8.1 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF904 PF06005.7 EEA06803.1 - 1.6 9.1 7.3 2.2 8.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Fmp27_WPPW PF10359.4 EEA06803.1 - 1.6 7.0 8.3 1.7 6.9 1.2 2.0 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain YkyA PF10368.4 EEA06803.1 - 1.7 7.9 11.6 1.9 7.7 1.3 2.1 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Allexi_40kDa PF05549.6 EEA06803.1 - 3.7 6.7 5.2 4.5 6.4 0.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Med9 PF07544.8 EEA06803.1 - 4.3 7.1 6.6 5.3 6.8 0.8 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CDC37_N PF03234.9 EEA06803.1 - 4.5 7.5 8.3 17 5.7 5.7 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CCDC-167 PF15188.1 EEA06803.1 - 4.8 7.1 8.7 12 5.9 1.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.10 EEA06803.1 - 5.1 7.0 8.1 6.5 6.6 1.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF16 PF01519.11 EEA06803.1 - 5.8 7.1 7.2 50 4.1 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 V_ATPase_I PF01496.14 EEA06803.1 - 8.6 4.0 7.2 29 2.3 5.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3740 PF12548.3 EEA06803.1 - 9.5 6.4 7.4 13 6.0 0.5 2.1 2 0 0 2 2 2 0 Sulfatase protein PP2C PF00481.16 EEA06804.1 - 1.7e-15 57.0 1.0 4.4e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EEA06804.1 - 6.4e-13 48.8 0.0 1.1e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEA06804.1 - 3.4e-09 36.4 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Hydrolase_6 PF13344.1 EEA06804.1 - 0.12 12.2 0.0 11 5.9 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Rpp20 PF12328.3 EEA06805.1 - 2.4e-17 62.9 0.0 3.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EEA06805.1 - 3.3e-09 36.1 0.0 6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Alba AAA PF00004.24 EEA06809.1 - 1.7e-12 47.6 0.0 3.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEA06809.1 - 4.1e-10 38.9 0.1 6.7e-06 25.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEA06809.1 - 9.8e-06 25.4 0.7 6.1e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA06809.1 - 0.00028 21.6 1.3 0.0017 19.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EEA06809.1 - 0.00033 20.9 0.0 0.0014 18.8 0.0 2.1 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EEA06809.1 - 0.00038 19.6 0.0 0.00084 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEA06809.1 - 0.00046 19.9 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EEA06809.1 - 0.0045 16.9 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EEA06809.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA06809.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA06809.1 - 0.0062 16.6 0.2 0.039 14.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA06809.1 - 0.0097 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EEA06809.1 - 0.012 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EEA06809.1 - 0.017 15.4 0.3 0.017 15.4 0.2 2.8 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EEA06809.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEA06809.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RING_2 PF13639.1 EEA06810.1 - 0.00014 21.6 7.9 0.00027 20.6 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA06810.1 - 0.0017 18.3 8.4 0.0082 16.1 6.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEA06810.1 - 0.016 15.2 10.5 0.032 14.2 7.3 1.6 1 1 0 1 1 1 0 RING-variant domain Yip1 PF04893.12 EEA06810.1 - 0.062 12.8 0.5 0.087 12.3 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain C1_1 PF00130.17 EEA06810.1 - 0.11 12.2 6.9 0.24 11.1 3.4 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 EEA06810.1 - 0.11 12.1 9.0 0.1 12.2 4.8 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EEA06810.1 - 0.36 10.5 8.4 0.23 11.1 3.7 2.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EEA06810.1 - 0.43 10.3 8.3 0.22 11.2 3.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 START PF01852.14 EEA06811.1 - 0.0085 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 START domain CHB_HEX_C PF03174.8 EEA06812.1 - 0.00019 21.1 0.2 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Med4 PF10018.4 EEA06812.1 - 0.012 15.0 0.1 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CHB_HEX_C_1 PF13290.1 EEA06812.1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 EEA06812.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Fn3 associated XPC-binding PF09280.6 EEA06814.1 - 5.4e-22 77.0 4.4 1.3e-21 75.7 3.1 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EEA06814.1 - 1.2e-20 72.6 3.8 4.3e-11 42.3 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EEA06814.1 - 2.6e-16 58.7 0.6 4.9e-16 57.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA06814.1 - 6.7e-09 35.3 1.3 1.2e-08 34.4 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EEA06814.1 - 5e-05 22.8 0.0 0.0027 17.2 0.0 2.9 3 0 0 3 3 3 1 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EEA06814.1 - 7.4e-05 22.8 0.3 0.00015 21.8 0.2 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEA06814.1 - 9.8e-05 22.2 1.6 0.00019 21.3 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LCAT PF02450.10 EEA06814.1 - 0.0078 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase GDI PF00996.13 EEA06815.1 - 4.8e-48 163.5 0.0 1e-22 80.1 0.0 3.0 1 1 1 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EEA06815.1 - 0.11 12.5 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA06815.1 - 0.15 10.9 0.0 0.42 9.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ribosomal_S4e PF00900.15 EEA06817.1 - 1.3e-24 85.6 1.3 2.1e-24 84.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EEA06817.1 - 9.6e-21 73.3 3.4 2.1e-20 72.2 1.5 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EEA06817.1 - 5.6e-08 32.0 0.0 9.8e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEA06817.1 - 0.00049 19.7 0.9 0.0029 17.2 0.2 2.6 2 0 0 2 2 2 1 KOW motif RNA_pol_Rpb6 PF01192.17 EEA06818.1 - 6.3e-22 77.0 0.5 1.3e-21 76.0 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 GST_C_3 PF14497.1 EEA06819.1 - 0.0078 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA06819.1 - 0.087 13.0 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain P22_AR_C PF10548.4 EEA06819.1 - 0.093 12.6 0.1 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 P22AR C-terminal domain PP2C PF00481.16 EEA06820.1 - 0.028 13.8 0.0 2 7.7 0.0 2.7 3 0 0 3 3 3 0 Protein phosphatase 2C Scramblase PF03803.10 EEA06820.1 - 0.065 12.3 0.1 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Scramblase Aa_trans PF01490.13 EEA06822.1 - 3.1e-49 167.5 29.8 3.8e-49 167.2 20.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PA14 PF07691.7 EEA06823.1 - 3.5e-25 88.3 0.0 9.6e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 PA14 domain F5_F8_type_C PF00754.20 EEA06823.1 - 0.0026 17.5 0.2 0.0069 16.2 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain BLOC1_2 PF10046.4 EEA06823.1 - 0.014 15.4 2.0 0.045 13.8 1.4 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSBP1 PF06825.7 EEA06823.1 - 0.06 12.9 0.0 2.4 7.7 0.3 2.7 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF4559 PF15112.1 EEA06823.1 - 0.22 10.6 4.6 1.4 7.9 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) Laminin_II PF06009.7 EEA06823.1 - 0.47 10.1 3.4 0.69 9.6 0.3 2.6 2 1 1 3 3 3 0 Laminin Domain II Herpes_UL45 PF05473.7 EEA06824.1 - 0.047 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 UL45 protein zf-C3HC4_2 PF13923.1 EEA06824.1 - 0.32 11.0 3.8 1 9.4 2.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MS_channel PF00924.13 EEA06825.1 - 1.1e-18 67.2 2.3 1.1e-18 67.2 1.6 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF1625 PF07787.7 EEA06825.1 - 0.71 9.0 8.4 0.04 13.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Phosducin PF02114.11 EEA06826.1 - 2.8e-07 29.5 0.3 2.8e-07 29.5 0.2 1.4 1 1 1 2 2 2 1 Phosducin DUF1221 PF06760.6 EEA06826.1 - 1.8e-05 24.1 0.5 3.1e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) Thioredoxin PF00085.15 EEA06826.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin EF-1_beta_acid PF10587.4 EEA06826.1 - 0.24 11.5 1.8 0.52 10.5 1.2 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pkinase PF00069.20 EEA06827.1 - 8e-59 198.8 0.1 9.5e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06827.1 - 2.1e-31 108.9 0.0 2.9e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEA06827.1 - 7e-05 22.2 0.5 0.0001 21.7 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EEA06827.1 - 0.00028 19.8 5.1 0.00068 18.5 3.6 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 PIP49_C PF12260.3 EEA06827.1 - 0.00032 20.1 0.1 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kinase-like PF14531.1 EEA06827.1 - 0.0061 15.5 0.0 0.014 14.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EEA06827.1 - 0.032 13.7 1.0 0.049 13.1 0.7 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEA06827.1 - 0.11 11.4 0.1 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA06827.1 - 0.23 11.1 0.2 0.45 10.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family rRNA_processing PF08524.6 EEA06830.1 - 0.00019 21.2 14.4 0.00025 20.8 10.0 1.2 1 0 0 1 1 1 1 rRNA processing PNPase PF03726.9 EEA06830.1 - 0.028 14.6 5.0 0.037 14.2 3.5 1.4 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3010 PF11215.3 EEA06830.1 - 0.065 13.1 0.8 0.076 12.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) U3_snoRNA_assoc PF08297.6 EEA06830.1 - 0.56 10.4 8.8 0.89 9.8 6.1 1.4 1 0 0 1 1 1 0 U3 snoRNA associated Selenoprotein_S PF06936.6 EEA06830.1 - 1 8.8 5.2 1.1 8.7 3.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) UCH PF00443.24 EEA06833.1 - 1.1e-29 103.3 10.3 2.1e-29 102.5 5.9 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA06833.1 - 3.3e-13 49.7 10.2 3.3e-12 46.4 7.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.1 EEA06834.1 - 8.1e-15 54.3 3.2 1.6e-14 53.4 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA06834.1 - 7.3e-09 35.5 4.6 1.5e-08 34.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA06834.1 - 4.4e-08 33.1 2.7 9.7e-08 32.0 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA06834.1 - 2.3e-07 30.3 3.9 4.8e-07 29.3 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA06834.1 - 1.3e-05 24.7 3.2 1.3e-05 24.7 2.2 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EEA06834.1 - 0.00054 19.6 3.3 0.0011 18.6 0.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 EEA06834.1 - 0.00066 19.3 4.5 0.0013 18.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA06834.1 - 0.004 16.9 1.5 0.0093 15.7 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA06834.1 - 0.0044 16.5 2.4 0.0085 15.6 1.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEA06834.1 - 0.06 13.0 2.8 0.12 12.1 1.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EEA06834.1 - 0.062 13.3 0.6 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EEA06834.1 - 0.084 12.8 4.0 0.45 10.5 2.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EEA06834.1 - 0.14 12.2 4.2 0.3 11.1 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EEA06834.1 - 0.15 11.7 2.3 0.31 10.7 1.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-DHHC PF01529.15 EEA06834.1 - 0.24 10.7 7.3 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Phospholip_B PF04916.8 EEA06835.1 - 0.11 10.6 0.0 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B Alg14 PF08660.6 EEA06836.1 - 9.4e-31 107.0 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Aldedh PF00171.17 EEA06837.1 - 2.7e-17 62.2 0.4 1.1e-09 37.2 0.1 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA06837.1 - 0.035 13.3 0.1 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Fumble PF03630.9 EEA06838.1 - 1.3e-38 132.7 12.0 7.2e-18 64.5 0.0 3.7 3 1 0 3 3 3 3 Fumble Rubrerythrin PF02915.12 EEA06838.1 - 0.054 13.8 3.0 0.51 10.6 0.1 2.3 2 0 0 2 2 2 0 Rubrerythrin zf-RING_4 PF14570.1 EEA06839.1 - 1.5e-18 66.0 19.4 3.9e-18 64.7 13.4 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EEA06839.1 - 5e-08 32.6 0.1 1.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA06839.1 - 9e-08 31.6 0.1 2.5e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06839.1 - 0.0002 21.2 0.0 0.00046 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EEA06839.1 - 0.0057 16.4 15.2 0.016 15.0 10.5 1.8 1 0 0 1 1 1 1 Ring finger domain DUF4355 PF14265.1 EEA06839.1 - 0.051 13.5 0.6 0.051 13.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) zf-UDP PF14569.1 EEA06839.1 - 8.8 6.1 11.0 0.6 9.8 3.3 2.3 3 0 0 3 3 3 0 Zinc-binding RING-finger EF-hand_7 PF13499.1 EEA06840.1 - 1.5e-06 28.2 4.4 2.7e-05 24.2 2.7 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA06840.1 - 0.0018 17.4 0.0 0.99 8.8 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EEA06840.1 - 0.011 15.5 0.1 1.6 8.8 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.20 EEA06841.1 - 1e-42 146.1 0.0 1.5e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06841.1 - 1.6e-41 142.0 0.0 2.3e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.17 EEA06843.1 - 4.9e-18 64.5 0.3 1.1e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06843.1 - 1.9e-14 53.3 0.1 3.7e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EEA06843.1 - 3e-09 36.8 0.6 6.5e-09 35.7 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 EEA06843.1 - 4.8e-08 32.7 0.2 8.7e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EEA06843.1 - 0.31 10.8 0.0 0.31 10.8 0.0 2.1 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4615 PF15393.1 EEA06843.1 - 0.39 10.9 5.1 0.079 13.1 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) zf-MYND PF01753.13 EEA06845.1 - 9.3e-13 47.8 9.4 2.1e-12 46.7 6.5 1.6 1 1 0 1 1 1 1 MYND finger DUF3846 PF12957.2 EEA06845.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Ecl1 PF12855.2 EEA06845.1 - 0.34 10.2 3.4 0.69 9.2 2.4 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Thioredoxin PF00085.15 EEA06846.1 - 3.4e-29 100.5 0.0 1.6e-19 69.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA06846.1 - 1.2e-15 57.7 4.5 3.4e-11 43.3 0.4 3.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEA06846.1 - 1e-05 25.6 0.0 0.0064 16.6 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA06846.1 - 0.00013 22.0 0.4 0.046 13.8 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EEA06846.1 - 0.0013 18.6 0.0 0.0073 16.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like DUF836 PF05768.9 EEA06846.1 - 0.0033 17.6 0.0 1.5 9.1 0.0 2.9 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) TraF PF13728.1 EEA06846.1 - 0.033 13.6 0.0 9.9 5.5 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 EEA06846.1 - 0.051 13.5 0.2 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin Redoxin PF08534.5 EEA06846.1 - 0.1 12.1 0.0 5.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Redoxin Bud13 PF09736.4 EEA06847.1 - 8.5e-33 113.6 0.6 1.1e-32 113.3 0.4 1.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex AP2 PF00847.15 EEA06849.1 - 2.6e-30 104.3 9.8 1.2e-15 57.4 2.2 3.4 3 0 0 3 3 3 3 AP2 domain WD40 PF00400.27 EEA06850.1 - 9.1e-13 47.5 3.7 0.0078 16.0 0.0 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF916 PF06030.7 EEA06850.1 - 0.066 13.0 0.2 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Lactamase_B_2 PF12706.2 EEA06851.1 - 4.2e-13 49.2 0.5 5.9e-13 48.8 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA06851.1 - 1.4e-07 31.3 0.0 1.6e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily ACDC PF14733.1 EEA06851.1 - 0.11 12.6 2.1 0.21 11.7 0.2 2.3 2 0 0 2 2 2 0 AP2-coincident C-terminal OPA3 PF07047.7 EEA06855.1 - 7.2e-11 42.0 1.5 3.9e-10 39.6 1.0 1.8 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) WBP-1 PF11669.3 EEA06855.1 - 0.1 12.6 0.2 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4063 PF13272.1 EEA06855.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) Radical_SAM PF04055.16 EEA06856.1 - 9.7e-05 22.5 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EEA06856.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EEA06856.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain FWWh PF14922.1 EEA06856.1 - 0.033 13.6 0.2 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF624 PF04854.9 EEA06856.1 - 0.044 13.6 1.8 0.055 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 AAA PF00004.24 EEA06857.1 - 7.6e-43 145.8 0.0 3.5e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEA06857.1 - 2.9e-07 30.5 0.0 7.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEA06857.1 - 2.2e-06 27.8 0.1 0.00027 21.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA06857.1 - 1.4e-05 24.2 0.0 2.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEA06857.1 - 2.8e-05 23.1 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEA06857.1 - 5.2e-05 23.0 0.2 0.00043 20.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA06857.1 - 6.9e-05 22.9 0.0 0.00027 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEA06857.1 - 0.00029 21.6 0.1 0.00083 20.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA06857.1 - 0.00077 19.3 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA06857.1 - 0.00089 18.7 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEA06857.1 - 0.0014 18.3 0.3 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEA06857.1 - 0.0025 18.1 0.2 0.0067 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA06857.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA06857.1 - 0.0034 16.7 1.0 0.17 11.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EEA06857.1 - 0.0036 17.2 0.5 0.0091 15.9 0.0 2.0 3 0 0 3 3 1 1 AAA domain TIP49 PF06068.8 EEA06857.1 - 0.0043 15.8 0.0 0.0093 14.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EEA06857.1 - 0.0063 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EEA06857.1 - 0.0077 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EEA06857.1 - 0.0083 15.7 0.4 0.031 13.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA06857.1 - 0.01 15.4 0.0 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EEA06857.1 - 0.014 14.5 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA06857.1 - 0.019 14.5 0.1 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EEA06857.1 - 0.025 13.8 0.1 0.087 12.0 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EEA06857.1 - 0.033 13.0 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EEA06857.1 - 0.035 13.2 0.1 0.7 8.9 0.0 2.3 1 1 1 2 2 2 0 KaiC Arch_ATPase PF01637.13 EEA06857.1 - 0.07 12.8 0.1 0.39 10.3 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EEA06857.1 - 0.08 13.2 0.1 0.32 11.2 0.1 2.3 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EEA06857.1 - 0.095 12.4 0.7 0.91 9.2 0.1 2.8 2 1 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 EEA06857.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Yippee-Mis18 PF03226.9 EEA06858.1 - 9.7e-15 54.3 0.4 1.2e-14 54.1 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Auto_anti-p27 PF06677.7 EEA06858.1 - 0.00022 20.9 0.4 0.07 12.9 0.0 2.3 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Mss51 PF13824.1 EEA06858.1 - 0.011 15.5 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_ribbon_2 PF12674.2 EEA06858.1 - 0.016 15.5 0.8 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2 PF00096.21 EEA06858.1 - 0.026 14.8 0.8 0.99 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DZR PF12773.2 EEA06858.1 - 0.033 14.0 0.2 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 EEA06858.1 - 0.046 13.5 0.2 0.046 13.5 0.1 2.0 1 1 0 2 2 2 0 Zinc-ribbon RIG-I_C-RD PF11648.3 EEA06858.1 - 0.05 13.4 0.3 0.072 12.9 0.2 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I zf-B_box PF00643.19 EEA06858.1 - 0.052 13.4 0.8 8.8 6.3 0.1 2.3 2 0 0 2 2 2 0 B-box zinc finger TF_Zn_Ribbon PF08271.7 EEA06858.1 - 0.066 12.5 1.5 5.3 6.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EEA06858.1 - 0.075 12.2 0.1 9.1 5.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EEA06858.1 - 0.087 12.5 0.9 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.9 EEA06858.1 - 0.093 12.6 0.4 5.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CpXC PF14353.1 EEA06858.1 - 0.13 12.2 0.3 16 5.4 0.0 2.1 2 0 0 2 2 2 0 CpXC protein DNA_RNApol_7kD PF03604.8 EEA06858.1 - 0.22 11.0 1.5 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.1 EEA06858.1 - 0.22 11.8 1.0 1.9 8.8 0.1 2.1 1 1 0 2 2 2 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 EEA06858.1 - 0.51 9.8 4.1 9 5.8 0.2 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain KIAA1430 PF13879.1 EEA06859.1 - 1.2 9.5 8.6 2 8.9 5.9 1.6 1 1 0 1 1 1 0 KIAA1430 homologue SpoIIIAH PF12685.2 EEA06859.1 - 7.2 6.0 8.4 1.6 8.1 1.2 2.0 1 1 0 2 2 2 0 SpoIIIAH-like protein UFD1 PF03152.9 EEA06860.1 - 3.4e-77 257.5 0.0 4.2e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Erythrovirus_X PF06795.6 EEA06860.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Erythrovirus X protein CDC48_N PF02359.13 EEA06860.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain KH_1 PF00013.24 EEA06861.1 - 1.1e-06 28.1 0.2 4.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 KH domain zf-CCHC_3 PF13917.1 EEA06861.1 - 0.00039 20.0 0.5 0.47 10.2 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EEA06861.1 - 0.0097 15.8 7.3 0.042 13.7 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EEA06861.1 - 0.042 13.5 6.3 0.15 11.7 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle KH_3 PF13014.1 EEA06861.1 - 0.05 13.2 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 KH domain RRS1 PF04939.7 EEA06862.1 - 2.3e-41 141.0 6.1 4.1e-41 140.1 4.3 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) LETM1 PF07766.8 EEA06862.1 - 0.36 9.8 4.3 4.1 6.3 2.2 2.1 1 1 1 2 2 2 0 LETM1-like protein Ribosomal_L28e PF01778.12 EEA06863.1 - 1e-27 96.8 4.4 1.1e-27 96.6 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family RolB_RolC PF02027.12 EEA06863.1 - 0.032 13.3 0.1 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family tRNA_int_endo PF01974.12 EEA06865.1 - 3.3e-17 62.0 0.0 6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Myb_DNA-binding PF00249.26 EEA06866.1 - 0.094 12.7 0.0 0.27 11.3 0.0 1.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain Rtf2 PF04641.7 EEA06867.1 - 9.2e-45 152.8 0.0 1.2e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EEA06867.1 - 0.0025 17.4 0.1 0.0075 15.9 0.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EEA06867.1 - 0.0027 17.1 1.0 0.45 10.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit Rick_17kDa_Anti PF05433.10 EEA06868.1 - 0.19 11.3 8.6 0.46 10.1 6.0 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain SbmA_BacA PF05992.7 EEA06870.1 - 6.5e-53 179.9 12.7 8e-53 179.6 8.8 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family SbmA_BacA PF05992.7 EEA06871.1 - 3.9e-60 203.6 5.0 4.7e-60 203.4 3.4 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.10 EEA06871.1 - 7.7e-07 28.5 2.7 1.1e-06 28.0 0.1 2.2 2 1 0 2 2 2 1 ABC transporter transmembrane region 2 Metallophos PF00149.23 EEA06872.1 - 3.5e-13 49.4 6.2 1.1e-12 47.8 4.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA06872.1 - 0.00041 20.2 0.1 0.0027 17.5 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aa_trans PF01490.13 EEA06873.1 - 1.2e-53 182.0 45.2 2e-53 181.3 31.4 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEA06873.1 - 1.5 7.5 38.5 3.4 6.3 26.7 1.6 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family DUF543 PF04418.7 EEA06876.1 - 0.00021 21.1 0.1 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF3100 PF11299.3 EEA06876.1 - 0.051 12.7 0.1 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) FtsX PF02687.16 EEA06876.1 - 0.081 12.6 0.8 0.26 11.0 0.6 1.8 1 1 0 1 1 1 0 FtsX-like permease family LSM PF01423.17 EEA06878.1 - 3.8e-17 61.5 0.3 5.2e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA06878.1 - 0.055 13.3 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain PIG-L PF02585.12 EEA06879.1 - 3.2e-23 82.6 0.0 3.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase KH_1 PF00013.24 EEA06881.1 - 3e-09 36.3 2.9 2.5e-08 33.4 1.6 2.3 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EEA06881.1 - 7.9e-08 31.7 2.4 1.9e-07 30.5 1.7 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EEA06881.1 - 0.18 11.4 1.4 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 KH domain RRM_1 PF00076.17 EEA06885.1 - 3.5e-32 109.8 0.5 5.3e-15 54.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06885.1 - 1.4e-23 82.6 0.1 2.5e-11 43.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06885.1 - 1.6e-17 63.1 0.8 4.1e-10 39.3 0.1 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YkyB PF14177.1 EEA06889.1 - 0.039 14.0 0.1 0.082 13.0 0.1 1.6 1 0 0 1 1 1 0 YkyB-like protein Metallophos PF00149.23 EEA06890.1 - 7.2e-41 139.7 0.9 9.1e-41 139.4 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA06890.1 - 0.034 13.9 0.0 0.047 13.5 0.0 1.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1227 PF06777.6 EEA06891.1 - 1.7e-45 154.3 1.6 2.6e-45 153.6 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EEA06891.1 - 2.6e-43 147.8 0.0 5.6e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEA06891.1 - 2.4e-30 105.2 10.0 3.3e-20 72.2 2.8 4.9 3 1 0 3 3 3 2 DEAD_2 ResIII PF04851.10 EEA06891.1 - 3.4e-08 33.5 0.9 1.8e-06 27.9 0.0 3.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA06891.1 - 0.0048 16.4 0.1 0.33 10.4 0.1 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EEA06891.1 - 0.065 12.0 0.0 4.5 5.9 0.0 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain TGT PF01702.13 EEA06892.1 - 1.5e-89 299.3 0.1 1.9e-89 299.0 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase AXH PF08517.7 EEA06893.1 - 0.018 15.1 0.4 0.029 14.5 0.3 1.3 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Peroxin-13_N PF04088.8 EEA06893.1 - 0.1 12.5 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Patched PF02460.13 EEA06894.1 - 1.2e-97 327.7 23.8 1.4e-64 218.3 6.5 3.3 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EEA06894.1 - 3.6e-31 107.6 24.7 1.9e-30 105.3 2.7 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation NifW PF03206.9 EEA06894.1 - 0.021 14.8 0.0 0.1 12.7 0.0 2.2 1 0 0 1 1 1 0 Nitrogen fixation protein NifW ACR_tran PF00873.14 EEA06894.1 - 0.061 10.7 11.1 0.11 9.8 7.7 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HR1 PF02185.11 EEA06896.1 - 0.003 17.2 4.6 0.0072 16.0 3.2 1.6 1 0 0 1 1 1 1 Hr1 repeat MRP-S26 PF14943.1 EEA06896.1 - 0.018 14.6 1.5 0.027 14.0 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2435 PF10363.4 EEA06896.1 - 0.054 13.3 0.3 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) eIF2A PF08662.6 EEA06897.1 - 5.4e-51 173.0 0.1 3e-42 144.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEA06897.1 - 0.00049 19.8 0.1 16 5.5 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.27 EEA06899.1 - 0.12 12.3 1.9 4.5 7.3 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat PGK PF00162.14 EEA06901.1 - 5.6e-146 486.0 0.4 6.3e-146 485.8 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NARP1 PF12569.3 EEA06902.1 - 3.2e-57 194.4 28.3 5.8e-48 163.9 13.6 3.9 3 1 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EEA06902.1 - 1.9e-10 40.2 17.4 5.4e-05 22.7 0.0 7.3 5 2 2 7 7 7 4 TPR repeat TPR_19 PF14559.1 EEA06902.1 - 1.1e-08 35.2 10.9 0.3 11.4 0.0 6.0 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06902.1 - 1.4e-07 30.8 19.4 0.00021 20.9 0.0 8.8 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA06902.1 - 1.6e-06 27.4 16.9 0.0069 15.9 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA06902.1 - 2.7e-06 27.5 0.0 11 7.0 0.0 6.2 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06902.1 - 2.4e-05 24.1 13.2 0.0061 16.4 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06902.1 - 5e-05 23.1 14.1 0.026 14.6 0.0 6.7 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06902.1 - 0.00049 19.6 18.0 0.064 13.0 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06902.1 - 0.00069 19.2 2.0 20 5.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06902.1 - 0.0023 18.5 2.4 23 5.8 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06902.1 - 0.45 11.0 9.8 1.1e+02 3.6 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat Seipin PF06775.9 EEA06903.1 - 2.9e-12 46.5 2.3 7.1e-10 38.7 1.6 2.3 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) RRM_1 PF00076.17 EEA06904.1 - 6e-18 64.2 0.0 9.5e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06904.1 - 1.6e-16 60.0 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06904.1 - 8e-11 41.6 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA06904.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SecY PF00344.15 EEA06905.1 - 1.8e-95 319.8 21.0 2.2e-95 319.5 14.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEA06905.1 - 2.4e-19 68.5 0.1 9.8e-19 66.5 0.1 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2205 PF10224.4 EEA06906.1 - 0.0024 17.3 3.9 0.011 15.3 0.6 3.3 3 0 0 3 3 3 1 Predicted coiled-coil protein (DUF2205) Sugarporin_N PF11471.3 EEA06906.1 - 3.3 7.4 7.4 0.26 10.9 1.3 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension TPR_14 PF13428.1 EEA06907.1 - 0.039 14.5 0.0 80 4.2 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06907.1 - 0.13 12.5 1.0 19 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06907.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 EEA06908.1 - 8e-30 103.0 2.1 1.2e-14 54.3 0.0 3.7 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA06908.1 - 3.4e-22 77.0 3.9 4.8e-05 22.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EEA06908.1 - 5.5e-17 60.1 2.1 0.0072 16.4 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EEA06908.1 - 1.3e-13 50.7 1.1 0.0002 21.5 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA06908.1 - 2.2e-11 43.9 2.6 0.00017 21.9 0.1 5.9 4 2 2 6 6 6 3 Ankyrin repeats (many copies) 2OG-FeII_Oxy_2 PF13532.1 EEA06910.1 - 4.2e-17 62.6 0.0 5.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEA06910.1 - 1e-09 38.5 0.2 2.6e-09 37.2 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RRM_5 PF13893.1 EEA06910.1 - 6.7e-05 22.6 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3638 PF12340.3 EEA06911.1 - 1.6e-19 69.8 0.7 2e-18 66.2 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EEA06911.1 - 5.5e-15 54.2 0.2 1.2e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_6 PF13405.1 EEA06911.1 - 1.2e-07 30.9 0.7 0.012 15.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EEA06911.1 - 1.4e-05 24.0 0.7 0.042 13.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EEA06911.1 - 0.00032 20.7 0.7 1.2 9.3 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA06911.1 - 0.032 13.5 0.5 9.6 5.7 0.1 2.8 2 0 0 2 2 2 0 EF hand Trypan_PARP PF05887.6 EEA06911.1 - 1.9 8.2 2.4 3.7 7.3 1.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.10 EEA06911.1 - 4.8 5.1 7.1 7.7 4.5 4.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family TerY-C PF15616.1 EEA06912.1 - 0.00076 19.4 1.1 0.0022 17.9 0.8 1.7 1 0 0 1 1 1 1 TerY-C metal binding domain Lar_restr_allev PF14354.1 EEA06912.1 - 0.0065 16.7 0.5 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar CpXC PF14353.1 EEA06912.1 - 0.018 14.9 2.0 0.04 13.8 0.2 2.3 2 1 0 2 2 2 0 CpXC protein Elf1 PF05129.8 EEA06912.1 - 0.059 13.0 2.4 0.14 11.8 1.7 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EEA06912.1 - 0.079 13.0 1.6 3.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-XS PF03470.9 EEA06912.1 - 2.5 8.2 9.6 5.4 7.1 0.9 2.7 2 0 0 2 2 2 0 XS zinc finger domain ATP-grasp_2 PF08442.5 EEA06913.1 - 3e-55 186.7 3.8 6.7e-48 162.7 0.2 2.4 1 1 0 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.14 EEA06913.1 - 1.1e-19 70.5 1.6 2.1e-19 69.6 1.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEA06913.1 - 0.0031 17.1 0.1 0.0078 15.8 0.1 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain G10 PF01125.12 EEA06914.1 - 8.4e-54 181.0 5.4 9.1e-54 180.9 3.8 1.0 1 0 0 1 1 1 1 G10 protein RNase_T PF00929.19 EEA06915.1 - 1.2e-13 51.6 0.0 2.9e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Exonuclease S4 PF01479.20 EEA06916.1 - 3.7e-08 32.6 0.0 1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 S4 domain zf-SNAP50_C PF12251.3 EEA06917.1 - 5.2e-48 163.0 5.8 1.1e-47 161.9 4.0 1.6 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal NicO PF03824.11 EEA06918.1 - 0.0056 16.0 0.1 0.0094 15.2 0.1 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein RED_N PF07808.8 EEA06918.1 - 0.22 10.7 3.6 0.37 9.9 2.5 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region LSM PF01423.17 EEA06919.1 - 6.3e-12 44.8 2.1 9.8e-12 44.2 1.5 1.3 1 0 0 1 1 1 1 LSM domain DUF1461 PF07314.6 EEA06919.1 - 0.081 12.6 2.0 0.092 12.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) JAB PF01398.16 EEA06920.1 - 6.9e-14 51.5 0.2 4.1e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEA06920.1 - 3.7e-06 26.9 0.7 5.5e-06 26.4 0.1 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Flavodoxin_2 PF02525.12 EEA06921.1 - 3.3e-32 111.6 0.0 3.7e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EEA06921.1 - 7.3e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EEA06921.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin ABC-3 PF00950.12 EEA06921.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ABC 3 transport family RRP7 PF12923.2 EEA06922.1 - 0.0019 18.2 0.5 0.0054 16.7 0.3 1.8 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) NTF2 PF02136.15 EEA06922.1 - 0.0042 17.4 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain IQ PF00612.22 EEA06923.1 - 0.0018 17.7 0.7 0.0087 15.6 0.1 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif cwf21 PF08312.7 EEA06924.1 - 1.8e-10 40.4 1.4 1.8e-10 40.4 1.0 1.9 2 0 0 2 2 2 1 cwf21 domain DUF2502 PF10697.4 EEA06924.1 - 2.4 8.3 10.2 0.13 12.3 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2502) zf-CCCH PF00642.19 EEA06925.1 - 3.6e-14 52.0 12.6 1e-06 28.2 1.2 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L29e PF01779.12 EEA06925.1 - 2.1 8.2 6.9 0.28 11.0 1.0 2.4 3 0 0 3 3 3 0 Ribosomal L29e protein family Bromodomain PF00439.20 EEA06926.1 - 2.1e-23 82.0 0.2 8.2e-23 80.1 0.2 2.1 1 0 0 1 1 1 1 Bromodomain TMF_TATA_bd PF12325.3 EEA06927.1 - 0.0004 20.0 17.9 0.0004 20.0 12.4 10.1 4 2 7 11 11 11 3 TATA element modulatory factor 1 TATA binding FPL PF09758.4 EEA06928.1 - 1.5e-34 118.9 7.7 1.5e-34 118.9 5.3 6.2 7 1 0 7 7 7 1 Uncharacterised conserved protein HA2 PF04408.18 EEA06929.1 - 1.3e-11 44.4 0.3 1e-10 41.5 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA06929.1 - 3.8e-11 42.6 0.1 1.6e-10 40.6 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA06929.1 - 2.2e-05 24.0 0.1 5.7e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UPF0079 PF02367.12 EEA06929.1 - 0.033 13.8 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DND1_DSRM PF14709.1 EEA06929.1 - 0.05 13.8 0.6 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.1 EEA06929.1 - 0.11 12.5 1.9 0.9 9.6 1.3 2.4 1 1 0 1 1 1 0 AAA domain zf-RanBP PF00641.13 EEA06930.1 - 2e-05 23.5 4.6 2e-05 23.5 3.2 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.1 EEA06930.1 - 0.0015 18.1 6.5 0.0015 18.1 4.5 5.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA06930.1 - 0.0053 16.7 10.7 0.0053 16.7 7.4 6.3 6 1 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EEA06930.1 - 2 8.9 21.9 2.9 8.4 0.1 6.7 6 0 0 6 6 6 0 C2H2-type zinc finger Cir_N PF10197.4 EEA06931.1 - 8.2e-12 44.9 7.9 2.1e-11 43.6 5.5 1.8 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR TPX2 PF06886.6 EEA06931.1 - 3 7.9 8.0 7.3 6.7 5.6 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Pkinase PF00069.20 EEA06932.1 - 1.2e-31 109.7 2.7 3.5e-31 108.2 1.8 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06932.1 - 1.9e-11 43.5 0.7 5.1e-11 42.1 0.5 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA06932.1 - 0.022 13.8 0.0 0.062 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fer4_NifH PF00142.13 EEA06933.1 - 1 8.5 3.3 0.41 9.7 0.4 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Biotin_lipoyl PF00364.17 EEA06934.1 - 8.9e-12 44.4 1.7 1.8e-11 43.5 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EEA06934.1 - 5.6e-05 22.7 0.6 0.16 11.6 0.2 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 EEA06934.1 - 0.02 14.2 0.1 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein DUF2675 PF11247.3 EEA06934.1 - 0.071 13.1 0.3 0.38 10.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2675) SNURF PF07192.6 EEA06935.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 2 0 0 2 2 2 0 SNURF/RPN4 protein Peptidase_S13 PF02113.10 EEA06937.1 - 0.042 12.3 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Imm31 PF15595.1 EEA06937.1 - 0.044 13.5 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 31 ALMT PF11744.3 EEA06937.1 - 0.39 9.3 3.5 0.77 8.3 2.4 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter YtfJ_HI0045 PF09695.5 EEA06939.1 - 0.04 13.2 0.1 2.6 7.3 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) Pkinase PF00069.20 EEA06940.1 - 3.7e-65 219.6 0.1 7e-65 218.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06940.1 - 1.1e-37 129.5 0.0 1.8e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EEA06940.1 - 2.3e-27 92.1 12.0 9.5e-05 21.4 0.3 5.7 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EEA06940.1 - 2.4e-27 94.8 8.0 5.1e-10 39.3 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 EEA06940.1 - 1.3e-22 79.1 10.4 3.6e-05 23.2 0.2 5.5 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.1 EEA06940.1 - 9.1e-21 71.8 10.4 0.00071 19.2 0.3 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.1 EEA06940.1 - 8.3e-20 69.1 14.1 8.1e-05 21.7 0.3 5.8 5 0 0 5 5 5 5 EF hand Kdo PF06293.9 EEA06940.1 - 1.3e-06 27.6 0.7 3.3e-05 23.0 0.0 2.9 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 EEA06940.1 - 3.9e-06 26.8 4.2 0.53 10.3 0.0 4.5 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 EEA06940.1 - 0.00023 20.2 0.5 0.0014 17.6 0.1 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EEA06940.1 - 0.0098 15.6 0.0 0.09 12.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family EF-hand_4 PF12763.2 EEA06940.1 - 0.021 14.5 2.8 1.6 8.5 0.0 3.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand TMEM117 PF15113.1 EEA06940.1 - 0.026 13.1 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 TMEM117 protein family YrbL-PhoP_reg PF10707.4 EEA06940.1 - 0.036 13.4 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cauli_VI PF01693.11 EEA06940.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin Glyco_tran_WbsX PF14307.1 EEA06940.1 - 0.059 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase WbsX Glycos_transf_2 PF00535.21 EEA06945.1 - 2e-17 63.4 0.5 4.4e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEA06945.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 EEA06945.1 - 1.7e-05 24.8 0.0 6e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 EEA06945.1 - 2.5e-05 23.5 0.0 4.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EEA06945.1 - 0.00093 18.6 0.6 0.002 17.5 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_trans_2_3 PF13632.1 EEA06945.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Pkinase PF00069.20 EEA06946.1 - 9.1e-36 123.3 0.0 6.4e-35 120.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06946.1 - 7.1e-08 31.8 0.1 1.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA06946.1 - 0.0004 20.1 0.1 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEA06947.1 - 5.2e-50 170.0 0.0 3.4e-49 167.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA06947.1 - 4.8e-31 107.7 0.0 3.2e-30 105.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Sec5 PF15469.1 EEA06948.1 - 0.0037 16.9 0.3 0.009 15.7 0.2 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 HCaRG PF07258.9 EEA06948.1 - 0.0062 16.0 0.1 0.074 12.5 0.0 2.7 2 0 0 2 2 2 1 HCaRG protein Baculo_PEP_C PF04513.7 EEA06949.1 - 0.019 14.8 1.2 0.04 13.7 0.8 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ste5 PF11610.3 EEA06949.1 - 0.035 13.6 0.1 9.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region CRAL_TRIO_2 PF13716.1 EEA06950.1 - 7.1e-13 48.7 1.2 2.4e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EEA06950.1 - 4e-06 26.4 0.3 4e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO domain SbmA_BacA PF05992.7 EEA06952.1 - 6.7e-39 133.9 11.3 7.7e-39 133.7 7.8 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family SbmA_BacA PF05992.7 EEA06953.1 - 4.9e-59 200.0 14.0 5.5e-59 199.9 9.7 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.10 EEA06953.1 - 0.00059 19.0 15.6 0.011 14.8 10.8 2.5 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 DUF3523 PF12037.3 EEA06955.1 - 8.9e-94 313.5 26.6 1.3e-93 313.0 18.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 EEA06955.1 - 4.1e-21 75.5 0.0 8.4e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA06955.1 - 0.00011 22.4 0.2 0.046 13.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA06955.1 - 0.00024 20.2 0.0 0.0006 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA06955.1 - 0.0036 17.3 0.0 0.2 11.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEA06955.1 - 0.0043 16.5 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EEA06955.1 - 0.019 15.2 0.0 0.019 15.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EEA06955.1 - 0.021 13.9 0.1 0.14 11.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA06955.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA06955.1 - 0.036 14.8 4.6 0.043 14.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEA06955.1 - 0.047 13.0 0.3 0.15 11.4 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.6 EEA06955.1 - 0.089 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA06955.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.3 2 2 0 2 2 2 0 AAA domain DUF2800 PF10926.3 EEA06956.1 - 0.11 11.5 1.8 0.14 11.2 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2800) PhoD PF09423.5 EEA06957.1 - 3.1e-18 65.5 0.0 5.5e-16 58.1 0.0 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase TPR_11 PF13414.1 EEA06958.1 - 2.1e-24 84.9 3.0 2.6e-08 33.3 0.0 4.8 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEA06958.1 - 4.2e-20 70.4 0.1 0.00079 18.9 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06958.1 - 7.7e-20 69.1 0.4 0.014 15.2 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEA06958.1 - 1.3e-19 68.6 0.4 0.00069 19.6 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEA06958.1 - 3.5e-15 56.0 0.2 0.0001 22.5 0.0 5.6 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA06958.1 - 1e-13 51.0 5.9 0.00052 19.8 0.0 5.5 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEA06958.1 - 2.3e-12 47.2 0.0 0.002 18.7 0.0 4.8 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA06958.1 - 2.4e-12 45.6 0.1 0.46 10.3 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEA06958.1 - 8.6e-12 44.5 0.0 0.013 16.1 0.0 6.6 4 2 4 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA06958.1 - 3.2e-09 35.9 4.4 0.23 11.2 0.1 6.4 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA06958.1 - 6.3e-09 35.8 13.9 0.0058 16.7 0.5 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEA06958.1 - 1.1e-08 34.7 0.0 0.0048 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEA06958.1 - 1.1e-08 34.9 0.0 0.03 14.7 0.0 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEA06958.1 - 1.7e-08 33.8 0.9 2.7e-05 23.3 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat APC8 PF04049.8 EEA06958.1 - 3.5e-06 26.8 0.1 8.5e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_10 PF13374.1 EEA06958.1 - 0.024 14.5 0.0 6.5 6.8 0.0 3.7 5 0 0 5 5 2 0 Tetratricopeptide repeat TFIIB PF00382.14 EEA06959.1 - 0.0037 17.0 0.1 0.21 11.3 0.0 2.8 2 0 0 2 2 2 1 Transcription factor TFIIB repeat TetR_N PF00440.18 EEA06959.1 - 0.022 14.3 0.1 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_7 PF02796.10 EEA06959.1 - 0.038 13.8 4.8 0.05 13.4 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DUF2653 PF10850.3 EEA06959.1 - 0.045 14.0 0.1 5.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) DUF3390 PF11870.3 EEA06959.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) HTH_38 PF13936.1 EEA06959.1 - 0.23 11.0 2.3 0.78 9.3 0.3 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Ribosomal_S27e PF01667.12 EEA06960.1 - 8.6e-26 89.2 6.2 1.1e-25 88.8 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Prok-RING_1 PF14446.1 EEA06960.1 - 0.017 14.8 2.9 0.026 14.2 2.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.16 EEA06960.1 - 0.017 14.9 2.8 0.022 14.6 1.9 1.3 1 0 0 1 1 1 0 IBR domain FYVE_2 PF02318.11 EEA06960.1 - 0.13 12.1 1.6 0.16 11.9 1.1 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EEA06960.1 - 0.17 11.1 3.7 0.62 9.3 2.4 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 EEA06960.1 - 0.24 11.3 3.0 0.88 9.5 2.1 1.9 1 1 0 1 1 1 0 B-box zinc finger Zn_Tnp_IS1 PF03811.8 EEA06960.1 - 3.4 7.2 6.2 0.89 9.1 1.0 2.3 1 1 1 2 2 2 0 InsA N-terminal domain dCMP_cyt_deam_1 PF00383.17 EEA06961.1 - 6.4e-09 35.3 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CBS PF00571.23 EEA06962.1 - 0.00032 20.4 0.9 0.0032 17.2 0.1 2.8 3 0 0 3 3 3 1 CBS domain THF_DHG_CYH_C PF02882.14 EEA06962.1 - 0.069 12.2 1.0 0.21 10.6 0.1 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA-synt_1b PF00579.20 EEA06963.1 - 4.7e-18 65.3 0.0 2.9e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Iso_dh PF00180.15 EEA06964.1 - 1.3e-68 231.5 0.0 1.5e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase His_Phos_2 PF00328.17 EEA06965.1 - 7.9e-52 176.7 0.0 1.1e-49 169.6 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EEA06965.1 - 1.7e-05 24.4 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EEA06965.1 - 0.00013 22.1 0.0 0.00065 19.8 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) FKBP_C PF00254.23 EEA06967.1 - 1.5e-06 28.1 0.1 3.3e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EEA06967.1 - 3.4e-05 23.3 0.1 4.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EEA06967.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA06967.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NOB1_Zn_bind PF08772.6 EEA06968.1 - 2.5e-23 81.6 0.1 5.2e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like tRNA-synt_2 PF00152.15 EEA06969.1 - 2.3e-77 260.0 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EEA06969.1 - 0.00053 19.2 0.1 0.44 9.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EEA06969.1 - 0.00089 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2012 PF09430.5 EEA06969.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) zf-DHHC PF01529.15 EEA06971.1 - 2.7e-36 124.5 10.1 2.7e-36 124.5 7.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Lactamase_B_2 PF12706.2 EEA06973.1 - 3.9e-22 78.7 0.0 5.7e-20 71.6 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEA06973.1 - 1.7e-08 33.7 0.0 5e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEA06973.1 - 1.8e-07 30.9 0.0 1.6e-05 24.6 0.1 3.2 4 0 0 4 4 4 1 Metallo-beta-lactamase superfamily DUF3960 PF13142.1 EEA06973.1 - 0.078 12.7 0.3 0.78 9.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3960) WHIM2 PF15613.1 EEA06974.1 - 0.00056 19.7 0.0 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 UDG PF03167.14 EEA06975.1 - 5e-23 81.2 0.0 7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily adh_short PF00106.20 EEA06976.1 - 2.3e-23 82.9 0.0 2.9e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA06976.1 - 2.7e-11 43.4 0.0 3.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA06976.1 - 1.4e-06 28.2 0.5 1.8e-06 27.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEA06976.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_L10 PF00466.15 EEA06977.1 - 6.6e-14 51.6 0.1 1.1e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RRM_1 PF00076.17 EEA06979.1 - 2.5e-16 59.0 0.0 3.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA06979.1 - 4.3e-14 52.2 0.0 1.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA06979.1 - 4.1e-13 48.9 0.1 7.6e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF39 PF01837.11 EEA06979.1 - 0.00042 19.0 0.4 0.00051 18.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF39 E1-E2_ATPase PF00122.15 EEA06980.1 - 1.2e-16 60.4 0.0 1.2e-16 60.4 0.0 3.0 3 1 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EEA06980.1 - 2.2e-09 37.7 0.1 3.2e-08 33.9 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA06980.1 - 5.6e-09 36.7 0.0 0.00066 20.1 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA06980.1 - 9.2e-07 28.7 0.0 3.3e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit SRP54 PF00448.17 EEA06981.1 - 1.5e-74 249.7 0.0 3.4e-74 248.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EEA06981.1 - 1.6e-27 95.8 0.6 1.6e-27 95.8 0.4 2.8 2 1 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 EEA06981.1 - 2.1e-15 56.5 2.0 4e-15 55.6 1.4 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EEA06981.1 - 1.8e-06 27.4 0.3 1.3e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEA06981.1 - 2.1e-06 27.6 0.3 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEA06981.1 - 1.9e-05 24.3 0.0 5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA06981.1 - 5.3e-05 23.3 0.3 0.00048 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EEA06981.1 - 0.00016 21.1 0.1 0.0014 18.0 0.1 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA06981.1 - 0.00039 20.3 0.0 1.1 9.1 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA06981.1 - 0.0019 19.0 0.0 0.0037 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA06981.1 - 0.0028 17.6 2.0 0.029 14.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EEA06981.1 - 0.0034 17.0 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA06981.1 - 0.0076 15.3 0.0 0.034 13.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 EEA06981.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.13 EEA06981.1 - 0.028 13.5 0.0 0.066 12.2 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2209 PF09974.4 EEA06981.1 - 0.031 14.3 0.4 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) ResIII PF04851.10 EEA06981.1 - 0.044 13.6 0.2 0.32 10.7 0.1 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 EEA06981.1 - 0.045 13.3 0.3 0.15 11.5 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EEA06981.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EEA06981.1 - 0.068 13.4 0.2 0.3 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEA06981.1 - 0.58 9.3 6.8 4.5 6.4 0.1 3.0 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit DDE_Tnp_1_3 PF13612.1 EEA06981.1 - 0.61 9.8 3.1 0.23 11.1 0.2 1.7 2 0 0 2 2 1 0 Transposase DDE domain NTPase_1 PF03266.10 EEA06981.1 - 0.62 9.7 3.2 5 6.8 0.3 2.7 2 1 0 2 2 1 0 NTPase ER_lumen_recept PF00810.13 EEA06982.1 - 2.2e-35 122.2 7.8 2.2e-35 122.2 5.4 1.9 2 1 0 2 2 2 1 ER lumen protein retaining receptor FixP_N PF14715.1 EEA06982.1 - 8.3 5.8 7.5 18 4.8 1.5 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP STOP PF05217.7 EEA06983.1 - 1.6e-09 37.8 13.1 1.7e-06 27.9 3.7 2.6 1 1 1 2 2 2 2 STOP protein IBN_N PF03810.14 EEA06984.1 - 3.6e-06 26.8 1.6 1.5e-05 24.8 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ras PF00071.17 EEA06985.1 - 5.2e-56 188.4 0.0 6.1e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA06985.1 - 4.5e-19 69.1 0.0 8e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA06985.1 - 1.5e-12 47.0 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA06985.1 - 2.2e-06 27.6 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA06985.1 - 2.2e-06 26.9 0.2 4.8e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA06985.1 - 3.7e-05 23.2 0.0 0.00058 19.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEA06985.1 - 0.00034 20.6 0.2 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EEA06985.1 - 0.0006 19.3 0.2 0.013 15.0 0.2 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EEA06985.1 - 0.0007 18.8 0.1 0.0012 18.0 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA06985.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEA06985.1 - 0.0043 16.6 0.3 0.0079 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA06985.1 - 0.0053 16.4 0.3 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase Septin PF00735.13 EEA06985.1 - 0.0061 15.6 0.1 0.041 12.8 0.0 2.0 2 0 0 2 2 2 1 Septin cobW PF02492.14 EEA06985.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EEA06985.1 - 0.018 14.4 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 EEA06985.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EEA06985.1 - 0.02 14.4 0.1 0.81 9.1 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EEA06985.1 - 0.021 14.5 0.1 0.044 13.4 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EEA06985.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EEA06985.1 - 0.11 12.7 0.2 0.25 11.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Rad51 PF08423.6 EEA06986.1 - 4e-129 428.9 0.1 5.9e-129 428.4 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA06986.1 - 1.9e-10 40.4 0.0 4.1e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 EEA06986.1 - 2.5e-09 36.6 0.1 3.7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EEA06986.1 - 5.5e-09 36.0 1.0 1.7e-08 34.4 0.6 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA PF00004.24 EEA06986.1 - 0.001 19.2 0.4 0.0094 16.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EEA06986.1 - 0.0016 17.6 1.4 0.0019 17.3 0.2 1.8 2 1 0 2 2 2 1 KaiC HHH PF00633.18 EEA06986.1 - 0.0039 16.8 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_22 PF13401.1 EEA06986.1 - 0.013 15.6 0.1 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_3 PF12836.2 EEA06986.1 - 0.022 14.6 1.1 0.077 12.9 0.1 2.5 2 1 1 3 3 3 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.10 EEA06986.1 - 0.024 14.0 0.5 0.048 13.0 0.4 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH_6 PF14579.1 EEA06986.1 - 0.04 13.9 1.1 0.87 9.6 0.1 2.8 2 1 1 3 3 3 0 Helix-hairpin-helix motif Band_7 PF01145.20 EEA06986.1 - 0.13 12.1 0.5 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 SPFH domain / Band 7 family Histone PF00125.19 EEA06987.1 - 4.3e-19 68.4 0.3 6e-19 67.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA06987.1 - 0.00035 20.5 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEA06987.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A tRNA-synt_2b PF00587.20 EEA06988.1 - 7.9e-40 136.2 0.3 1.2e-39 135.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA06988.1 - 2.6e-20 72.1 0.0 5.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EEA06988.1 - 9.4e-14 51.0 0.1 3.1e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EEA06988.1 - 2.9e-05 23.8 0.0 9.7e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 TGS domain HhH-GPD PF00730.20 EEA06990.1 - 1.9e-22 79.5 0.0 2.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEA06990.1 - 4.6e-09 35.4 0.0 9.4e-09 34.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EEA06990.1 - 0.0021 18.1 6.0 0.0035 17.4 4.2 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 EEA06990.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.1 EEA06990.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain LCCL PF03815.14 EEA06991.1 - 1.2e-20 73.2 0.2 1.2e-20 73.2 0.1 2.6 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.20 EEA06991.1 - 0.00014 21.7 0.1 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain PHD PF00628.24 EEA06992.1 - 0.00024 20.7 6.1 0.00062 19.4 4.2 1.8 1 0 0 1 1 1 1 PHD-finger MerR-DNA-bind PF09278.6 EEA06992.1 - 0.12 12.8 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 MerR, DNA binding Slu7 PF11708.3 EEA06993.1 - 7.1e-55 186.3 15.8 9.5e-55 185.9 10.9 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor E1-E2_ATPase PF00122.15 EEA06994.1 - 3.9e-15 55.5 0.0 1.8e-14 53.3 0.0 2.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEA06994.1 - 5e-15 56.5 0.0 1.2e-07 32.3 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA06994.1 - 5.8e-14 52.7 0.0 1.2e-12 48.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA06994.1 - 0.00034 20.4 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA06994.1 - 0.0036 16.9 1.6 0.0036 16.9 1.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 EEA06995.1 - 5.4e-06 25.7 0.0 8.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA06995.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like T4_baseplate PF12322.3 EEA06995.1 - 0.054 12.7 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein ToxN_toxin PF13958.1 EEA06995.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system Xpo1 PF08389.7 EEA06996.1 - 3.8e-22 78.8 12.9 2.8e-21 76.0 0.0 4.7 4 0 0 4 4 4 3 Exportin 1-like protein ARID PF01388.16 EEA06997.1 - 9.6e-13 47.8 0.0 3.5e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TIM21 PF08294.6 EEA06997.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 TIM21 HHH_5 PF14520.1 EEA06998.1 - 0.0054 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Glyco_trans_1_4 PF13692.1 EEA07000.1 - 1.5e-13 51.0 0.0 2.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA07000.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEA07000.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEA07000.1 - 0.085 12.2 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 SHP PF03579.8 EEA07000.1 - 0.25 10.7 4.4 0.82 9.0 3.1 1.9 1 0 0 1 1 1 0 Small hydrophobic protein ODV-E18 PF10717.4 EEA07000.1 - 3.5 7.1 6.1 7.5 6.0 4.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TRAPP PF04051.11 EEA07001.1 - 1.1e-33 115.8 0.1 1.5e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UDPGP PF01704.13 EEA07002.1 - 1.4e-14 53.4 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.20 EEA07003.1 - 3.3e-70 236.2 0.0 5.1e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07003.1 - 8e-29 100.4 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EEA07003.1 - 4.6e-18 63.0 9.0 2.5e-06 26.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EEA07003.1 - 1.1e-16 60.7 5.0 1.9e-11 43.9 1.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA07003.1 - 4.6e-16 57.2 0.8 0.00027 20.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EEA07003.1 - 3e-15 54.7 6.0 1.8e-05 23.8 0.1 3.5 3 0 0 3 3 3 3 EF hand CBM_20 PF00686.14 EEA07003.1 - 1.3e-12 47.1 0.5 3.1e-12 45.9 0.1 1.9 2 0 0 2 2 1 1 Starch binding domain EF-hand_8 PF13833.1 EEA07003.1 - 1.7e-11 43.5 9.6 1.9e-05 24.1 0.8 4.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 EEA07003.1 - 2.3e-05 24.2 0.4 0.00032 20.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain Kdo PF06293.9 EEA07003.1 - 0.00077 18.5 0.0 0.0034 16.4 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 EEA07003.1 - 0.0057 16.3 0.5 0.065 12.9 0.3 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEA07003.1 - 0.015 15.3 0.6 4.6 7.3 0.3 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Choline_kinase PF01633.15 EEA07003.1 - 0.028 13.9 0.1 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EEA07003.1 - 0.098 12.3 0.0 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FliG_N PF14842.1 EEA07003.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 FliG N-terminal domain DUF4284 PF14112.1 EEA07003.1 - 0.17 12.3 1.7 0.33 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) SMC_N PF02463.14 EEA07004.1 - 3.3e-74 248.8 12.8 2.1e-39 135.0 3.4 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA07004.1 - 4.6e-26 91.1 0.1 1.5e-25 89.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA07004.1 - 3.7e-11 43.5 25.9 3.6e-07 30.4 7.2 6.1 2 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 EEA07004.1 - 1.2e-07 31.1 0.0 2.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA07004.1 - 0.0077 16.5 0.0 0.0077 16.5 0.0 7.1 3 2 0 4 4 4 2 ABC transporter AAA_16 PF13191.1 EEA07004.1 - 0.037 13.9 2.9 0.24 11.3 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EEA07004.1 - 0.075 13.1 5.9 4.6 7.3 0.0 4.9 3 1 1 4 4 4 0 AAA domain EMP24_GP25L PF01105.19 EEA07005.1 - 1.4e-16 60.7 0.1 1.7e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_L44 PF00935.14 EEA07006.1 - 3.7e-31 106.9 15.9 4.7e-31 106.6 11.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EEA07006.1 - 0.11 12.7 6.9 1.2 9.3 0.3 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 KH_1 PF00013.24 EEA07007.1 - 1.3e-15 56.7 12.2 4e-10 39.1 0.7 5.8 5 0 0 5 5 5 2 KH domain KH_3 PF13014.1 EEA07007.1 - 9.9e-09 34.6 4.4 8.3e-06 25.3 0.2 4.3 5 0 0 5 5 5 2 KH domain KH_2 PF07650.12 EEA07007.1 - 0.011 15.3 0.5 0.067 12.7 0.4 2.4 1 0 0 1 1 1 0 KH domain Secretin_N PF03958.12 EEA07007.1 - 0.042 14.0 0.1 0.74 10.0 0.0 3.1 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain Pyr_redox_2 PF07992.9 EEA07008.1 - 4.8e-18 65.7 0.0 9.6e-17 61.5 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA07008.1 - 1.1e-06 28.9 0.2 4.8e-06 26.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HGTP_anticodon2 PF12745.2 EEA07008.1 - 0.054 12.6 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Adaptin_N PF01602.15 EEA07009.1 - 2.8e-78 263.5 22.9 4.9e-78 262.7 15.9 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EEA07009.1 - 6.4e-34 116.9 0.5 3.3e-33 114.6 0.1 2.2 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EEA07009.1 - 4e-09 36.6 0.8 0.042 14.1 0.0 4.8 2 1 4 6 6 6 4 HEAT repeats Cnd1 PF12717.2 EEA07009.1 - 0.0065 16.3 0.9 0.0065 16.3 0.6 4.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF2939 PF11159.3 EEA07009.1 - 0.036 14.2 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) HEAT PF02985.17 EEA07009.1 - 0.2 11.8 5.3 1.2e+02 3.2 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EEA07009.1 - 0.32 11.5 1.3 22 5.7 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Sld5 PF05916.6 EEA07010.1 - 1.5e-10 41.2 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SPT16 PF08644.6 EEA07011.1 - 3.2e-44 150.4 0.1 3.2e-44 150.4 0.0 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EEA07011.1 - 1.2e-25 89.9 0.4 2.6e-23 82.3 0.0 3.3 3 0 0 3 3 3 2 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EEA07011.1 - 3.5e-24 84.6 0.0 1.5e-23 82.6 0.0 2.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EEA07011.1 - 1.3e-17 64.0 0.0 2.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 GAS PF13851.1 EEA07012.1 - 0.027 13.6 32.0 0.25 10.5 0.9 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 EEA07012.1 - 0.066 12.1 1.6 0.14 11.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_19 PF12844.2 EEA07012.1 - 0.076 13.0 0.7 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain PspA_IM30 PF04012.7 EEA07012.1 - 5.4 6.2 12.5 0.23 10.7 1.6 2.4 2 1 1 3 3 3 0 PspA/IM30 family Polyketide_cyc PF03364.15 EEA07013.1 - 6.7e-13 48.7 0.0 1.5e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1106 PF06523.6 EEA07013.1 - 0.038 13.8 1.1 0.051 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) Ribosomal_S5_C PF03719.10 EEA07014.1 - 0.0082 15.4 0.3 0.019 14.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain NPL4 PF05021.10 EEA07015.1 - 8.3e-66 222.2 0.0 1.2e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 EEA07015.1 - 3.4e-17 62.4 0.1 8.3e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.10 EEA07015.1 - 4.4e-05 23.1 0.1 0.0001 21.9 0.0 1.5 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region ubiquitin PF00240.18 EEA07015.1 - 0.00014 21.2 0.0 0.00038 19.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Tubulin PF00091.20 EEA07016.1 - 2.1e-72 243.4 0.0 4.5e-72 242.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA07016.1 - 4.6e-45 152.7 0.6 1.1e-44 151.5 0.4 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEA07016.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EEA07016.1 - 0.049 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Hrs_helical PF12210.3 EEA07016.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ribosomal_L7Ae PF01248.21 EEA07017.1 - 1.2e-06 27.9 0.2 4.1e-06 26.2 0.0 1.9 2 1 1 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.20 EEA07018.1 - 1.9e-13 50.2 0.1 5e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EEA07019.1 - 7.6e-05 22.4 0.2 1.9 8.7 0.1 4.4 3 0 0 3 3 3 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EEA07019.1 - 0.0043 17.4 1.1 3.3 8.1 0.0 3.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EEA07019.1 - 0.0059 16.8 0.2 2.6 8.4 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats DUF1601 PF07671.6 EEA07019.1 - 1.8 8.2 8.1 0.056 13.0 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) Reticulon PF02453.12 EEA07020.1 - 5.5e-06 26.0 8.2 1e-05 25.1 5.7 1.5 1 1 0 1 1 1 1 Reticulon COPI_assoc PF08507.5 EEA07020.1 - 0.022 14.4 0.2 0.022 14.4 0.2 2.8 2 1 0 2 2 2 0 COPI associated protein DUF4014 PF13198.1 EEA07020.1 - 0.05 14.0 3.1 0.12 12.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) RabGAP-TBC PF00566.13 EEA07020.1 - 0.18 11.2 2.7 0.24 10.8 1.9 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain SIR2 PF02146.12 EEA07021.1 - 6.6e-23 81.3 0.0 8.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EEA07021.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain LSM PF01423.17 EEA07022.1 - 2e-15 56.0 0.1 2.3e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA07022.1 - 1.2e-06 28.3 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Aha1_N PF09229.6 EEA07023.1 - 3.8e-40 136.8 4.4 3e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 Activator of Hsp90 ATPase, N-terminal Metallophos_2 PF12850.2 EEA07024.1 - 1.9e-20 73.2 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEA07024.1 - 0.00019 20.8 0.1 0.00071 19.0 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M16_C PF05193.16 EEA07026.1 - 9.1e-28 97.1 0.0 2.2e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA07026.1 - 1e-23 83.7 0.1 3e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TIP49 PF06068.8 EEA07027.1 - 1.6e-179 596.7 0.2 1.8e-179 596.5 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEA07027.1 - 2.7e-11 43.8 0.1 2.9e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA07027.1 - 3e-09 36.2 0.6 1.3e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEA07027.1 - 4.8e-07 29.9 0.0 0.01 15.9 0.0 2.7 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA07027.1 - 1.8e-05 24.8 0.0 0.00064 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEA07027.1 - 0.00019 21.1 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEA07027.1 - 0.0003 20.2 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA07027.1 - 0.00076 18.7 0.2 0.031 13.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEA07027.1 - 0.0013 18.5 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEA07027.1 - 0.0018 17.7 0.1 0.0035 16.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEA07027.1 - 0.003 17.2 0.0 0.0091 15.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EEA07027.1 - 0.0032 16.9 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EEA07027.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EEA07027.1 - 0.0094 15.1 0.2 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 EEA07027.1 - 0.013 15.8 0.1 0.12 12.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EEA07027.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 EEA07027.1 - 0.023 15.5 0.0 0.065 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA07027.1 - 0.028 13.5 0.2 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 EEA07027.1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA07027.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEA07027.1 - 0.039 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EEA07027.1 - 0.11 12.3 0.1 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit WD40 PF00400.27 EEA07028.1 - 0.0043 16.8 1.5 0.091 12.6 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribosomal_L2_C PF03947.13 EEA07029.1 - 1.3e-41 141.4 2.4 1.9e-41 140.9 1.7 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEA07029.1 - 4.2e-15 55.4 0.1 1.4e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain XPG_I PF00867.13 EEA07032.1 - 1.3e-29 102.0 0.1 1.3e-29 102.0 0.0 2.7 3 1 0 3 3 3 1 XPG I-region XPG_N PF00752.12 EEA07032.1 - 1.5e-29 102.2 0.0 3.4e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.11 EEA07032.1 - 0.00015 21.1 0.0 0.00045 19.6 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EEA07032.1 - 0.00022 21.4 0.0 0.00022 21.4 0.0 3.4 2 1 1 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold EMP24_GP25L PF01105.19 EEA07033.1 - 3.7e-31 108.2 1.5 4.2e-31 108.0 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AhpC-TSA PF00578.16 EEA07034.1 - 6.9e-33 112.9 0.0 2.3e-29 101.5 0.0 2.1 1 1 1 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EEA07034.1 - 7.5e-13 48.2 0.0 2.6e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEA07034.1 - 1.2e-05 24.7 0.0 2.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PRP21_like_P PF12230.3 EEA07035.1 - 2.7e-49 167.7 10.9 2.7e-49 167.7 7.5 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EEA07035.1 - 6.7e-36 121.7 2.8 9.2e-17 60.4 0.0 3.4 3 0 0 3 3 3 2 Surp module PAT1 PF09770.4 EEA07036.1 - 1.7e-05 23.2 0.2 1.7e-05 23.2 0.1 2.8 3 0 0 3 3 3 2 Topoisomerase II-associated protein PAT1 Atx10homo_assoc PF09759.4 EEA07037.1 - 2.5e-08 33.5 0.5 2.5e-08 33.5 0.3 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Tn916-Xis PF09035.5 EEA07038.1 - 0.072 13.1 0.4 0.22 11.6 0.3 1.8 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Guanylate_kin PF00625.16 EEA07039.1 - 1.4e-49 168.0 0.2 1.6e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.1 EEA07039.1 - 1.3e-05 25.2 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA07039.1 - 3.6e-05 23.0 0.0 5.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEA07039.1 - 5e-05 24.1 0.3 0.00023 21.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA07039.1 - 0.0001 22.1 0.0 0.00037 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EEA07039.1 - 0.00013 22.4 0.1 0.00035 21.0 0.0 1.7 2 1 0 2 2 1 1 Miro-like protein AAA_18 PF13238.1 EEA07039.1 - 0.00033 20.9 1.0 0.0013 19.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEA07039.1 - 0.0013 18.6 0.3 0.003 17.5 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EEA07039.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EEA07039.1 - 0.0018 18.3 0.0 0.0037 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEA07039.1 - 0.0024 17.7 0.6 0.0055 16.6 0.1 1.9 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 EEA07039.1 - 0.0024 17.5 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EEA07039.1 - 0.003 17.8 0.2 0.0042 17.3 0.1 1.5 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EEA07039.1 - 0.0068 16.1 1.5 0.023 14.3 1.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EEA07039.1 - 0.015 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EEA07039.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Septin Thymidylate_kin PF02223.12 EEA07039.1 - 0.023 14.0 0.0 0.048 13.0 0.0 1.5 1 1 1 2 2 2 0 Thymidylate kinase Dynamin_N PF00350.18 EEA07039.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.7 2 0 0 2 2 2 0 Dynamin family Rad17 PF03215.10 EEA07039.1 - 0.03 13.0 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Ras PF00071.17 EEA07039.1 - 0.062 12.6 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Ras family G-alpha PF00503.15 EEA07039.1 - 0.063 11.9 0.1 0.081 11.5 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_21 PF13304.1 EEA07039.1 - 0.071 13.0 3.8 0.93 9.3 2.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA07039.1 - 0.072 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA07039.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EEA07039.1 - 0.13 12.0 0.1 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 NTPase DUF87 PF01935.12 EEA07039.1 - 0.13 12.0 0.9 0.86 9.3 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EEA07039.1 - 0.13 11.6 0.1 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEA07039.1 - 0.53 10.5 4.1 14 5.8 2.8 2.2 1 1 0 1 1 1 0 AAA domain DUF2585 PF10755.4 EEA07040.1 - 0.083 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) IncA PF04156.9 EEA07042.1 - 0.0027 17.3 17.4 0.0027 17.3 12.0 4.4 3 1 0 3 3 3 1 IncA protein Filament PF00038.16 EEA07042.1 - 0.074 12.5 40.9 0.5 9.7 8.3 3.6 3 0 0 3 3 3 0 Intermediate filament protein FMN_red PF03358.10 EEA07042.1 - 0.2 11.1 0.1 0.47 9.9 0.1 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF3338 PF11819.3 EEA07042.1 - 0.3 10.5 15.2 0.092 12.1 1.5 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) Ribosomal_S3_C PF00189.15 EEA07044.1 - 9.4e-19 67.4 0.1 2.3e-18 66.1 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EEA07044.1 - 1.2e-09 37.5 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF1682 PF07946.9 EEA07045.1 - 4.9e-56 189.9 13.2 8.3e-56 189.1 9.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_S9 PF00380.14 EEA07045.1 - 0.58 10.4 5.3 1.3 9.2 3.4 1.7 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Asp-B-Hydro_N PF05279.6 EEA07045.1 - 1 9.1 6.2 1.4 8.7 4.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ubiquitin PF00240.18 EEA07047.1 - 1.6e-35 120.3 0.5 2.1e-35 119.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEA07047.1 - 4.6e-28 96.5 10.8 7.4e-28 95.9 7.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEA07047.1 - 1.1e-20 73.0 0.4 1.8e-20 72.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA07047.1 - 1.8e-06 28.0 0.1 6.7e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEA07047.1 - 0.00027 20.6 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEA07047.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA07047.1 - 0.025 14.7 0.1 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EEA07047.1 - 0.045 13.6 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Fcf1 PF04900.7 EEA07048.1 - 2.2e-39 133.6 0.6 4.1e-39 132.7 0.4 1.4 1 0 0 1 1 1 1 Fcf1 DUF2462 PF09495.5 EEA07048.1 - 0.27 12.0 2.3 0.48 11.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) eIF-5a PF01287.15 EEA07049.1 - 6.7e-25 86.8 0.0 9.6e-25 86.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEA07049.1 - 0.0034 17.0 0.1 0.0061 16.2 0.1 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEA07049.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain AAA PF00004.24 EEA07050.1 - 5e-08 33.2 2.5 8.4e-07 29.2 1.7 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA07050.1 - 4.9e-07 29.9 0.5 7.1e-06 26.1 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA07050.1 - 0.00025 21.0 0.0 0.0091 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA07050.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EEA07050.1 - 0.0047 16.5 0.3 4.6 6.8 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_5 PF07728.9 EEA07050.1 - 0.016 14.9 0.0 0.42 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEA07050.1 - 0.037 13.2 0.5 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EEA07050.1 - 0.33 10.6 0.1 0.33 10.6 0.0 2.9 3 0 0 3 3 3 0 NTPase Myb_DNA-bind_3 PF12776.2 EEA07050.1 - 1.2 9.8 5.0 6.6 7.4 0.0 3.9 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain Thioesterase PF00975.15 EEA07051.1 - 3.8e-06 27.2 0.0 0.013 15.7 0.0 2.3 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EEA07051.1 - 5.5e-05 23.1 0.0 9e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA07051.1 - 6.6e-05 22.7 0.0 7.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA07051.1 - 0.0047 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EEA07051.1 - 0.013 14.4 0.1 0.043 12.7 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EEA07051.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Arf PF00025.16 EEA07052.1 - 1.7e-63 212.9 0.0 1.9e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEA07052.1 - 1.1e-12 47.3 1.1 1.5e-09 37.0 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEA07052.1 - 1.6e-12 47.0 0.0 1.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEA07052.1 - 3.9e-10 39.3 0.0 4.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07052.1 - 4.4e-10 40.0 0.0 6.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA07052.1 - 1.3e-07 31.6 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA07052.1 - 3.8e-07 29.4 0.0 4.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA07052.1 - 2.9e-05 23.6 0.0 0.0007 19.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EEA07052.1 - 0.02 14.3 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation F_actin_bind PF08919.5 EEA07053.1 - 0.0088 15.7 0.0 0.039 13.6 0.0 2.1 1 0 0 1 1 1 1 F-actin binding Herpes_UL45 PF05473.7 EEA07054.1 - 0.016 14.6 0.1 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 UL45 protein UPF0560 PF10577.4 EEA07054.1 - 5.1 5.2 8.9 6 4.9 6.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC50 PF03381.10 EEA07056.1 - 1.6e-22 80.0 4.9 1.6e-22 80.0 3.4 2.4 2 1 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FUN14 PF04930.10 EEA07056.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 FUN14 family EB1 PF03271.12 EEA07057.1 - 1.5e-13 50.5 0.8 1.5e-13 50.5 0.5 2.2 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 EEA07057.1 - 4.2e-07 29.9 3.3 8.6e-07 28.9 0.2 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF900 PF05990.7 EEA07057.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RNase_PH PF01138.16 EEA07058.1 - 3.1e-16 59.9 0.2 6.6e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEA07058.1 - 5.5e-09 35.8 0.2 3.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Tyr-DNA_phospho PF06087.7 EEA07059.1 - 7.9e-72 242.2 7.1 5e-71 239.6 4.9 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Methyltransf_7 PF03492.10 EEA07060.1 - 0.05 12.3 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Cpn10 PF00166.16 EEA07061.1 - 6.9e-21 73.9 0.0 9.3e-21 73.5 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cupin_1 PF00190.17 EEA07061.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 Cupin YfmQ PF10787.4 EEA07061.1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group ARD PF03079.9 EEA07061.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF3740 PF12548.3 EEA07062.1 - 0.039 14.2 0.2 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 Sulfatase protein Ribosomal_L22e PF01776.12 EEA07063.1 - 3.6e-47 158.9 0.4 4.1e-47 158.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Sipho_Gp157 PF05565.6 EEA07063.1 - 0.089 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 eIF-5_eIF-2B PF01873.12 EEA07064.1 - 2.2e-36 124.2 0.2 1.9e-35 121.2 0.0 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EEA07064.1 - 5.2e-13 48.7 0.0 6.5e-12 45.2 0.0 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Tho2 PF11262.3 EEA07065.1 - 6.3e-19 68.1 11.2 8.4e-16 57.8 4.5 3.1 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EEA07065.1 - 4.7e-06 26.2 1.7 2.1e-05 24.1 1.2 2.2 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RNA_capsid PF03035.9 EEA07065.1 - 0.096 12.4 3.4 0.17 11.6 2.3 1.4 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein MFS_1 PF07690.11 EEA07066.1 - 3.1e-09 36.0 30.7 3.1e-09 36.0 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DsbB PF02600.11 EEA07066.1 - 0.0057 16.4 12.9 0.028 14.1 3.1 3.8 3 1 0 3 3 3 2 Disulfide bond formation protein DsbB RabGAP-TBC PF00566.13 EEA07067.1 - 9.8e-20 70.9 9.9 2.4e-19 69.6 6.9 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 14-3-3 PF00244.15 EEA07068.1 - 1.9e-25 89.3 11.0 2.2e-25 89.1 7.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DNase-RNase PF02577.9 EEA07068.1 - 0.034 13.3 0.6 0.46 9.7 0.4 2.2 1 1 0 1 1 1 0 Bifunctional nuclease Latarcin PF10279.4 EEA07068.1 - 0.061 13.5 0.0 0.28 11.3 0.0 2.3 1 1 0 1 1 1 0 Latarcin precursor TMP_2 PF06791.8 EEA07068.1 - 0.088 12.4 0.7 5.2 6.6 0.0 2.3 2 1 0 2 2 2 0 Prophage tail length tape measure protein Rap1-DNA-bind PF09197.5 EEA07068.1 - 0.43 11.1 0.1 0.43 11.1 0.1 2.5 3 0 0 3 3 3 0 Rap1, DNA-binding zf-HIT PF04438.11 EEA07070.1 - 4.6e-05 22.9 16.5 4.6e-05 22.9 11.4 1.8 2 0 0 2 2 2 1 HIT zinc finger Cyclin PF08613.6 EEA07071.1 - 8e-19 68.5 0.1 1.9e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin Skp1 PF01466.14 EEA07072.1 - 3.7e-36 122.9 2.0 6.2e-36 122.2 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEA07072.1 - 1.5e-24 85.8 0.2 3e-24 84.8 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TauE PF01925.14 EEA07073.1 - 0.0018 17.7 12.6 0.0029 17.0 8.7 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4131 PF13567.1 EEA07073.1 - 0.11 11.9 8.9 0.35 10.2 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1240 PF06836.7 EEA07073.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) NMN_transporter PF04973.7 EEA07073.1 - 4.7 6.6 9.7 11 5.4 1.3 3.2 2 2 1 3 3 3 0 Nicotinamide mononucleotide transporter SbmA_BacA PF05992.7 EEA07074.1 - 3.3e-05 23.2 0.1 4.5e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 SbmA/BacA-like family Big_2 PF02368.13 EEA07076.1 - 0.027 14.3 0.4 0.089 12.6 0.3 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) Ribosomal_L35Ae PF01247.13 EEA07077.1 - 3.6e-37 126.0 0.9 4.5e-37 125.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae Abhydrolase_5 PF12695.2 EEA07078.1 - 5.1e-18 65.2 0.0 6.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA07078.1 - 6e-12 45.9 0.0 2.4e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA07078.1 - 3e-08 33.3 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EEA07078.1 - 6.9e-06 25.7 0.0 0.072 12.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EEA07078.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EEA07078.1 - 0.0023 17.2 0.0 0.081 12.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family FtsJ PF01728.14 EEA07080.1 - 3.6e-22 79.2 0.1 4.2e-21 75.7 0.0 2.7 3 0 0 3 3 3 1 FtsJ-like methyltransferase PS_pyruv_trans PF04230.8 EEA07081.1 - 3.1e-23 82.8 3.8 7.1e-22 78.4 2.7 2.3 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.11 EEA07082.1 - 2.4e-14 53.2 17.4 4.6e-05 23.1 0.4 4.1 4 0 0 4 4 4 3 Triose-phosphate Transporter family EamA PF00892.15 EEA07082.1 - 1.3e-05 25.2 4.7 1.3e-05 25.2 3.3 4.2 4 2 0 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EEA07082.1 - 0.0012 19.0 3.0 0.0012 19.0 2.1 3.8 3 1 2 5 5 5 1 Multidrug resistance efflux transporter Kelch_1 PF01344.20 EEA07084.1 - 2.3e-25 87.8 6.3 1.9e-08 33.7 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EEA07084.1 - 1.1e-22 79.2 4.1 0.00018 21.5 0.0 6.3 3 1 3 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EEA07084.1 - 3.6e-22 77.8 3.6 4.2e-05 23.2 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB_2 PF02214.17 EEA07084.1 - 2.1e-15 56.6 0.6 5.7e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 EEA07084.1 - 3.7e-14 52.4 4.7 0.014 15.5 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EEA07084.1 - 1.2e-07 31.1 6.1 0.33 10.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EEA07084.1 - 4.5e-06 26.4 1.4 3.9 7.5 0.1 4.8 4 0 0 4 4 4 2 Kelch motif 2OG-Fe_Oxy_2 PF10014.4 EEA07084.1 - 0.058 12.7 2.4 0.1 11.9 1.7 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase Arif-1 PF06770.6 EEA07084.1 - 0.073 12.4 1.3 0.13 11.6 0.9 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF342 PF03961.8 EEA07084.1 - 0.16 10.3 11.2 0.25 9.7 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) KfrA_N PF11740.3 EEA07084.1 - 3.6 8.0 8.5 4.3 7.8 4.3 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term AAA_2 PF07724.9 EEA07085.1 - 1.3e-30 106.5 0.1 1.5e-26 93.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEA07085.1 - 9.1e-28 97.0 0.4 2e-17 63.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA07085.1 - 3.1e-14 52.8 0.0 6.5e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA07085.1 - 8.5e-13 48.6 0.2 4.5e-06 26.7 0.0 4.4 3 1 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EEA07085.1 - 1.4e-10 42.0 3.9 2.5e-06 28.3 0.0 3.8 5 0 0 5 5 2 2 AAA domain AAA_22 PF13401.1 EEA07085.1 - 3.1e-10 40.2 0.0 0.00012 22.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain ClpB_D2-small PF10431.4 EEA07085.1 - 2.6e-09 36.8 0.9 9.1e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein IstB_IS21 PF01695.12 EEA07085.1 - 6.7e-09 35.3 0.1 0.0004 19.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEA07085.1 - 1.9e-07 30.4 0.1 0.00098 18.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EEA07085.1 - 3.2e-07 29.6 0.3 0.013 14.5 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA07085.1 - 7.4e-07 28.8 0.6 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EEA07085.1 - 8.9e-07 27.9 0.3 0.00038 19.2 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EEA07085.1 - 1.1e-06 28.2 0.1 0.0031 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEA07085.1 - 2.2e-06 27.7 1.4 0.00025 21.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EEA07085.1 - 2.7e-06 27.7 0.0 2.7e-06 27.7 0.0 4.8 4 2 2 6 6 4 1 AAA domain AAA_33 PF13671.1 EEA07085.1 - 4.3e-06 26.6 0.5 0.0017 18.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA07085.1 - 7.5e-06 26.0 3.0 0.063 13.4 0.0 4.4 5 0 0 5 5 3 2 RNA helicase T2SE PF00437.15 EEA07085.1 - 9.4e-06 24.7 0.4 0.034 13.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DEAD PF00270.24 EEA07085.1 - 2.5e-05 23.8 0.1 0.013 15.0 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Arch_ATPase PF01637.13 EEA07085.1 - 2.7e-05 23.9 13.0 0.0011 18.7 0.0 5.8 5 2 0 5 5 4 1 Archaeal ATPase PhoH PF02562.11 EEA07085.1 - 6.4e-05 22.2 2.2 0.095 11.9 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein AAA_14 PF13173.1 EEA07085.1 - 9.4e-05 22.3 5.6 0.00066 19.5 0.0 4.0 4 1 0 4 4 2 1 AAA domain Sigma54_activat PF00158.21 EEA07085.1 - 0.00011 21.7 0.3 0.58 9.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EEA07085.1 - 0.00014 21.5 0.8 0.024 14.3 0.0 2.9 3 0 0 3 3 2 1 NACHT domain NTPase_1 PF03266.10 EEA07085.1 - 0.00018 21.2 0.7 0.68 9.6 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_29 PF13555.1 EEA07085.1 - 0.00025 20.4 0.3 0.17 11.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA07085.1 - 0.00043 19.9 1.4 0.12 11.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.1 EEA07085.1 - 0.00058 19.5 0.0 0.17 11.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EEA07085.1 - 0.00066 19.1 0.5 0.06 12.8 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EEA07085.1 - 0.00071 19.8 3.6 0.094 13.0 0.1 3.1 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.7 EEA07085.1 - 0.0013 17.8 0.5 0.053 12.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 EEA07085.1 - 0.002 17.3 0.2 0.93 8.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_3 PF07726.6 EEA07085.1 - 0.0022 17.6 0.1 3.9 7.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EEA07085.1 - 0.0024 17.5 0.5 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEA07085.1 - 0.003 17.2 3.1 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 EEA07085.1 - 0.0031 16.5 0.0 0.015 14.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EEA07085.1 - 0.0035 16.2 0.0 0.21 10.3 0.0 2.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EEA07085.1 - 0.0036 16.8 0.8 1 8.7 0.0 3.7 2 1 0 3 3 3 1 AAA-like domain Sigma54_activ_2 PF14532.1 EEA07085.1 - 0.0058 16.6 0.0 0.52 10.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain SRP54 PF00448.17 EEA07085.1 - 0.0087 15.5 1.8 0.48 9.8 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ArgK PF03308.11 EEA07085.1 - 0.022 13.5 0.1 0.04 12.6 0.1 1.4 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 EEA07085.1 - 0.023 13.5 3.4 0.43 9.3 0.0 3.4 4 0 0 4 4 3 0 NB-ARC domain MMR_HSR1 PF01926.18 EEA07085.1 - 0.026 14.4 0.2 1.7 8.6 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EEA07085.1 - 0.04 13.5 0.6 2 8.0 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EEA07085.1 - 0.046 12.3 0.3 8 4.9 0.0 2.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Patatin PF01734.17 EEA07086.1 - 1.2e-05 25.2 0.1 0.00084 19.3 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_19 PF14559.1 EEA07087.1 - 1.2e-13 51.1 0.4 3.2e-07 30.5 0.1 3.0 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA07087.1 - 2.9e-08 33.2 0.6 0.0001 21.8 0.1 2.9 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EEA07087.1 - 5e-08 33.4 0.0 0.00015 22.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07087.1 - 8.8e-08 32.1 0.1 0.0098 16.4 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA07087.1 - 0.00021 21.2 0.1 0.61 10.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07087.1 - 0.00038 20.1 0.7 3.1 7.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA07087.1 - 0.002 18.3 0.0 4.7 7.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07087.1 - 0.0063 16.4 1.2 0.66 9.9 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EEA07087.1 - 0.15 11.7 1.5 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) S-AdoMet_synt_C PF02773.11 EEA07088.1 - 9.1e-62 206.8 0.0 1.4e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EEA07088.1 - 3.1e-43 146.5 0.0 5.3e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EEA07088.1 - 1.5e-40 137.4 0.1 2.6e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Rad17 PF03215.10 EEA07089.1 - 4.5e-27 94.9 16.0 4.7e-19 68.4 9.4 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEA07089.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EEA07089.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EEA07089.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EEA07089.1 - 0.043 14.6 0.0 0.16 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEA07089.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EEA07089.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 EEA07090.1 - 7.2e-45 152.8 1.0 8.7e-45 152.5 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adap_comp_sub PF00928.16 EEA07091.1 - 1.1e-80 270.5 0.4 1.4e-80 270.1 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEA07091.1 - 3e-07 30.2 2.2 5.6e-07 29.3 1.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2051 PF09738.4 EEA07091.1 - 4 6.6 5.1 19 4.4 0.3 2.4 3 0 0 3 3 3 0 Double stranded RNA binding protein (DUF2051) CENP-Q PF13094.1 EEA07092.1 - 0.031 14.3 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GIDA PF01134.17 EEA07092.1 - 0.039 12.7 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FCH PF00611.18 EEA07092.1 - 0.059 13.5 0.5 0.57 10.4 0.1 2.6 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain UBA_3 PF09288.5 EEA07092.1 - 4.2 7.0 9.0 12 5.5 0.1 4.0 4 1 0 4 4 4 0 Fungal ubiquitin-associated domain SMC_N PF02463.14 EEA07093.1 - 4.2e-45 153.6 33.8 1.3e-44 152.1 23.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA07093.1 - 1.3e-22 79.9 0.2 5.3e-22 78.0 0.2 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA07093.1 - 2.7e-12 47.2 7.5 7e-07 29.5 3.0 5.7 3 1 2 5 5 5 2 AAA domain AAA_29 PF13555.1 EEA07093.1 - 0.00022 20.6 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA07093.1 - 0.00081 19.7 0.0 0.00081 19.7 0.0 6.5 4 2 1 5 5 5 1 ABC transporter Reo_sigmaC PF04582.7 EEA07093.1 - 0.58 9.2 25.7 2 7.5 1.2 4.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DCP2 PF05026.8 EEA07094.1 - 3.9e-25 87.5 2.7 8.3e-25 86.5 1.9 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EEA07094.1 - 6.6e-12 45.2 0.1 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Trypan_glycop PF00913.14 EEA07094.1 - 0.37 9.6 1.0 0.58 9.0 0.7 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Bromodomain PF00439.20 EEA07095.1 - 6.6e-22 77.2 0.8 3e-21 75.1 0.1 2.5 2 0 0 2 2 2 1 Bromodomain Gp_UL130 PF11668.3 EEA07095.1 - 0.0022 17.4 1.2 0.12 11.8 0.1 3.2 2 1 1 3 3 3 1 HCMV glycoprotein pUL130 ABC_membrane_2 PF06472.10 EEA07096.1 - 1.4e-36 126.0 9.1 2.7e-36 125.1 6.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEA07096.1 - 2.2e-17 63.6 0.0 5.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.7 EEA07096.1 - 4.3e-05 22.8 4.7 0.00014 21.1 3.3 1.9 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_29 PF13555.1 EEA07096.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA07096.1 - 0.004 17.5 0.1 0.004 17.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.14 EEA07096.1 - 0.015 14.5 0.4 0.75 8.9 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA07096.1 - 0.032 14.2 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EEA07096.1 - 0.045 12.9 0.1 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF4059 PF13268.1 EEA07096.1 - 0.065 13.4 1.7 0.26 11.4 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) MMR_HSR1 PF01926.18 EEA07096.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.27 EEA07097.1 - 1.4e-12 46.9 14.2 0.0005 19.8 0.0 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat bZIP_1 PF00170.16 EEA07098.1 - 0.088 12.7 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor Striatin PF08232.7 EEA07098.1 - 0.19 12.0 2.4 0.5 10.6 1.7 1.7 1 1 0 1 1 1 0 Striatin family Fe_hyd_lg_C PF02906.9 EEA07100.1 - 1.1e-60 205.3 0.1 2.2e-60 204.3 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Arf PF00025.16 EEA07101.1 - 4.8e-69 231.0 0.2 5.5e-69 230.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA07101.1 - 8.3e-12 44.7 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA07101.1 - 2.6e-10 39.5 0.4 3.6e-05 22.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EEA07101.1 - 5.8e-10 39.7 0.0 8.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA07101.1 - 2.7e-07 30.5 0.0 3.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA07101.1 - 6.8e-07 28.6 0.0 7.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA07101.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EEA07101.1 - 8.7e-05 22.0 0.0 0.0014 18.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEA07101.1 - 0.0058 15.9 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B ArgK PF03308.11 EEA07101.1 - 0.011 14.4 0.1 0.075 11.7 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 EEA07101.1 - 0.051 14.3 0.0 0.068 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain TB2_DP1_HVA22 PF03134.14 EEA07102.1 - 0.00015 21.4 3.7 0.00025 20.7 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_C13 PF01650.13 EEA07103.1 - 5e-35 121.0 0.1 7.7e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family YcxB PF14317.1 EEA07103.1 - 0.042 13.0 0.1 0.16 11.2 0.1 2.1 1 0 0 1 1 1 0 YcxB-like protein eIF3_N PF09440.5 EEA07103.1 - 0.08 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Glycos_transf_1 PF00534.15 EEA07104.1 - 6.8e-25 87.4 0.0 1.4e-23 83.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA07104.1 - 1.4e-06 28.5 0.0 7.7e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEA07104.1 - 0.00085 19.5 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.24 EEA07106.1 - 8.6e-39 132.7 0.0 3.1e-38 130.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA07106.1 - 4.5e-26 90.5 0.0 1.9e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA07106.1 - 4.7e-07 29.8 0.0 3.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABA_GPCR PF12430.3 EEA07107.1 - 0.0096 15.0 1.0 0.12 11.5 0.1 2.4 1 1 1 2 2 2 1 Abscisic acid G-protein coupled receptor DUF843 PF05814.6 EEA07107.1 - 0.036 13.8 2.7 0.34 10.7 0.1 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) zf-C2H2_jaz PF12171.3 EEA07108.1 - 1.2e-06 28.5 6.5 0.00046 20.2 0.7 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEA07108.1 - 1.2e-05 25.2 5.3 0.038 14.3 0.5 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA07108.1 - 0.00048 20.3 7.6 0.062 13.6 0.4 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EEA07108.1 - 0.011 15.8 4.4 0.23 11.6 0.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EEA07108.1 - 0.011 15.7 4.5 1.3 9.1 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EEA07108.1 - 0.026 14.4 0.2 0.026 14.4 0.1 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EEA07108.1 - 0.028 14.0 4.8 0.12 12.0 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.17 EEA07108.1 - 0.038 14.0 2.5 0.064 13.3 1.7 1.3 1 0 0 1 1 1 0 LIM domain PyrI_C PF02748.10 EEA07108.1 - 0.36 10.3 5.5 1.9 7.9 0.5 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.10 EEA07108.1 - 7.3 6.4 9.2 1.6 8.5 1.6 2.3 1 1 1 2 2 2 0 BED zinc finger adh_short PF00106.20 EEA07109.1 - 4.5e-14 52.7 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA07109.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain UCH PF00443.24 EEA07110.1 - 3.8e-39 134.4 0.5 4.6e-39 134.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA07110.1 - 1.3e-10 41.2 1.0 1.9e-10 40.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EEA07110.1 - 4.6e-08 32.3 0.0 1.7e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EEA07110.1 - 6.1e-05 23.2 0.0 0.00034 20.7 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-like domain Ribosomal_S21e PF01249.13 EEA07111.1 - 5e-35 119.3 0.0 5.4e-35 119.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e AP_endonuc_2 PF01261.19 EEA07112.1 - 3.9e-26 91.6 0.0 5.4e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sdh5 PF03937.11 EEA07113.1 - 4.7e-18 64.6 0.5 6.4e-18 64.2 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Oxysterol_BP PF01237.13 EEA07114.1 - 2.5e-112 374.9 0.2 3.2e-112 374.5 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein AAA PF00004.24 EEA07115.1 - 5e-93 308.2 0.0 5.3e-46 156.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEA07115.1 - 4.9e-23 80.8 0.5 1.3e-22 79.5 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EEA07115.1 - 5.8e-13 48.4 0.0 1e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEA07115.1 - 3.2e-12 47.3 0.2 1.4e-05 25.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EEA07115.1 - 4.6e-12 46.2 1.0 0.00014 21.9 0.0 3.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EEA07115.1 - 1.1e-11 44.9 0.1 0.00041 20.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA07115.1 - 3.1e-11 43.3 0.0 1.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EEA07115.1 - 4.1e-11 42.3 0.0 9.1e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 EEA07115.1 - 4.2e-11 43.0 0.0 7e-06 26.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA07115.1 - 5.2e-11 42.4 0.1 5.3e-06 26.1 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEA07115.1 - 2.9e-08 33.6 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EEA07115.1 - 5.6e-08 31.9 0.0 0.0012 17.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EEA07115.1 - 7.6e-08 31.9 0.9 0.042 13.2 0.0 3.7 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EEA07115.1 - 1.8e-07 30.4 0.0 0.0081 15.2 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_18 PF13238.1 EEA07115.1 - 4.6e-07 30.2 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EEA07115.1 - 7.2e-07 28.5 0.2 0.03 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEA07115.1 - 8e-07 28.6 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EEA07115.1 - 1.1e-06 28.7 0.0 0.023 14.8 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 EEA07115.1 - 2.8e-06 26.9 3.4 0.021 14.5 0.3 3.0 3 0 0 3 3 2 2 Part of AAA domain NACHT PF05729.7 EEA07115.1 - 3e-06 26.9 0.0 0.4 10.3 0.0 3.9 3 1 0 4 4 4 2 NACHT domain Arch_ATPase PF01637.13 EEA07115.1 - 4.2e-06 26.6 0.0 0.041 13.5 0.0 3.2 2 2 1 3 3 3 2 Archaeal ATPase AAA_28 PF13521.1 EEA07115.1 - 6.1e-06 26.2 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EEA07115.1 - 7.6e-06 26.0 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EEA07115.1 - 7.5e-05 21.9 0.1 1.9 7.5 0.0 3.4 2 1 1 3 3 3 1 KaiC AAA_24 PF13479.1 EEA07115.1 - 7.7e-05 22.3 0.1 0.39 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EEA07115.1 - 8e-05 22.1 0.0 0.1 12.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 EEA07115.1 - 9.5e-05 22.7 0.0 0.31 11.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ResIII PF04851.10 EEA07115.1 - 0.0001 22.1 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 EEA07115.1 - 0.00015 21.5 0.0 0.066 12.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Viral_helicase1 PF01443.13 EEA07115.1 - 0.00018 21.1 0.0 0.024 14.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EEA07115.1 - 0.00024 20.1 0.0 0.38 9.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEA07115.1 - 0.00024 20.0 0.0 0.6 8.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EEA07115.1 - 0.0014 17.8 0.1 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.10 EEA07115.1 - 0.0018 17.9 0.2 1.6 8.4 0.0 3.4 3 0 0 3 3 3 1 NTPase DUF815 PF05673.8 EEA07115.1 - 0.0025 16.7 0.0 0.52 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SKI PF01202.17 EEA07115.1 - 0.0029 17.5 0.1 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA_3 PF07726.6 EEA07115.1 - 0.0036 16.8 0.0 2.7 7.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EEA07115.1 - 0.0048 15.9 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 EEA07115.1 - 0.0071 16.2 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_30 PF13604.1 EEA07115.1 - 0.0085 15.6 0.0 4.8 6.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain UPF0079 PF02367.12 EEA07115.1 - 0.02 14.4 0.1 5.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EEA07115.1 - 0.037 13.0 0.1 1.3 7.8 0.0 2.9 2 2 2 4 4 4 0 KAP family P-loop domain AAA_11 PF13086.1 EEA07115.1 - 0.044 13.3 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEA07115.1 - 0.045 14.0 0.0 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA07115.1 - 0.045 13.1 0.3 6.9 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Cytidylate_kin2 PF13189.1 EEA07115.1 - 0.047 13.6 0.1 4.1 7.2 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family DEAD PF00270.24 EEA07115.1 - 0.056 12.9 0.0 20 4.6 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EEA07115.1 - 0.065 12.7 0.0 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 EEA07115.1 - 0.075 12.2 0.4 9.8 5.2 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Zot PF05707.7 EEA07115.1 - 0.099 12.0 0.2 8.1 5.8 0.1 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DAP3 PF10236.4 EEA07115.1 - 0.32 9.8 0.0 17 4.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Josephin PF02099.12 EEA07116.1 - 2.5e-44 150.6 0.0 5.3e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Josephin UBX PF00789.15 EEA07116.1 - 1.6e-05 24.8 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain G10 PF01125.12 EEA07116.1 - 0.081 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 G10 protein RRM_6 PF14259.1 EEA07117.1 - 4.6e-22 77.7 0.0 7.4e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07117.1 - 2e-11 43.5 0.0 1.2e-06 28.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA07117.1 - 2.3e-11 43.1 0.0 0.013 15.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Noc2 PF03715.8 EEA07118.1 - 5.2e-35 120.7 15.0 5.2e-35 120.7 10.4 2.0 2 1 0 2 2 2 1 Noc2p family Peptidase_M14 PF00246.19 EEA07119.1 - 2.4e-40 138.8 0.0 3.5e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Coq4 PF05019.8 EEA07120.1 - 4e-51 173.0 0.3 6.1e-46 156.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ISG65-75 PF11727.3 EEA07121.1 - 0.00093 18.3 1.4 0.00093 18.3 1.0 2.5 1 1 0 2 2 2 1 Invariant surface glycoprotein PBC PF03792.8 EEA07121.1 - 0.00098 18.8 8.9 0.008 15.8 3.0 3.1 1 1 1 2 2 2 1 PBC domain Adenyl_cycl_N PF12633.2 EEA07121.1 - 0.0044 16.5 1.8 0.01 15.3 1.2 1.9 1 1 0 1 1 1 1 Adenylate cyclase NT domain Apolipoprotein PF01442.13 EEA07121.1 - 0.0091 15.5 15.8 0.082 12.4 2.4 2.4 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF2365 PF10157.4 EEA07121.1 - 0.013 15.3 3.9 0.21 11.4 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) ING PF12998.2 EEA07121.1 - 0.018 15.3 23.2 0.43 10.8 4.0 3.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ArgK PF03308.11 EEA07121.1 - 0.091 11.5 0.6 0.18 10.5 0.4 1.5 1 0 0 1 1 1 0 ArgK protein Vps54 PF07928.7 EEA07121.1 - 0.12 12.5 7.7 0.46 10.6 0.1 3.7 2 2 2 4 4 4 0 Vps54-like protein Phage_Mu_Gam PF07352.7 EEA07121.1 - 0.16 11.5 18.3 0.12 11.9 2.5 3.1 2 2 1 3 3 3 0 Bacteriophage Mu Gam like protein OmpH PF03938.9 EEA07121.1 - 0.16 11.9 26.4 59 3.5 13.3 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1266 PF06889.6 EEA07121.1 - 0.31 10.8 3.1 1.2 8.9 0.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1266) Vir_act_alpha_C PF10400.4 EEA07121.1 - 1.9 8.9 6.0 6.2 7.2 0.2 3.0 2 2 1 3 3 3 0 Virulence activator alpha C-term DUF948 PF06103.6 EEA07121.1 - 2.1 8.2 13.0 5.5 6.9 0.3 3.9 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EEA07121.1 - 4 7.2 19.2 0.26 11.0 6.5 2.6 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.7 EEA07121.1 - 7.1 5.8 29.2 0.97 8.6 6.6 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Pkinase PF00069.20 EEA07122.1 - 3.8e-20 72.1 5.9 6.4e-20 71.3 1.1 3.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07122.1 - 3e-05 23.2 0.4 0.0047 16.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase BAF1_ABF1 PF04684.8 EEA07122.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UQ_con PF00179.21 EEA07123.1 - 1.8e-45 153.8 0.0 2.1e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA07123.1 - 0.0066 16.1 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Proteasome PF00227.21 EEA07124.1 - 2.6e-31 108.3 0.0 3.3e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit EMP24_GP25L PF01105.19 EEA07125.1 - 5.4e-26 91.4 1.2 1.4e-25 90.0 0.9 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ASFV_J13L PF05568.6 EEA07125.1 - 2.2 7.7 4.7 1.3 8.5 1.0 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein Peptidase_S24 PF00717.18 EEA07126.1 - 3.1e-11 42.7 0.2 4.5e-11 42.2 0.2 1.4 1 1 0 1 1 1 1 Peptidase S24-like DNA_ligase_OB PF03120.11 EEA07126.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain V-SNARE_C PF12352.3 EEA07127.1 - 0.021 14.9 1.0 0.046 13.7 0.7 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEA07127.1 - 0.039 13.6 5.8 0.075 12.7 3.1 2.2 1 1 0 1 1 1 0 Sec20 DUF1493 PF07377.7 EEA07127.1 - 0.044 13.8 0.4 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) WD40 PF00400.27 EEA07128.1 - 1.5e-16 59.5 14.2 6.8e-08 32.0 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Sec34 PF04136.10 EEA07128.1 - 0.082 12.6 0.4 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Sec34-like family BPL_LplA_LipB PF03099.14 EEA07129.1 - 1.7e-09 37.7 1.0 4.9e-09 36.2 0.2 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EEA07129.1 - 0.0097 15.5 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF262 PF03235.9 EEA07129.1 - 0.016 15.1 2.2 0.016 15.1 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF262 DUF3176 PF11374.3 EEA07129.1 - 0.1 12.4 0.1 0.79 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) WD40 PF00400.27 EEA07131.1 - 2.6e-15 55.6 6.2 7.6e-08 31.9 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat HPS3_N PF14761.1 EEA07131.1 - 9.3e-05 21.9 0.0 0.00059 19.3 0.0 2.0 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 LytTR PF04397.10 EEA07131.1 - 0.038 14.0 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 LytTr DNA-binding domain PD40 PF07676.7 EEA07131.1 - 0.043 13.5 0.1 23 4.7 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Homeobox PF00046.24 EEA07133.1 - 0.0042 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain FMN_bind PF04205.9 EEA07134.1 - 0.27 11.4 1.6 4 7.6 1.1 2.9 1 1 0 1 1 1 0 FMN-binding domain Ras PF00071.17 EEA07135.1 - 1.2e-60 203.5 0.1 1.5e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07135.1 - 1e-22 80.8 0.1 1.4e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA07135.1 - 2e-16 59.7 0.0 2.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA07135.1 - 0.00014 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA07135.1 - 0.00019 20.9 0.0 0.00058 19.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA07135.1 - 0.00054 19.9 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Big_3_2 PF12245.3 EEA07135.1 - 0.073 12.6 0.1 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) AAA_22 PF13401.1 EEA07135.1 - 0.14 12.3 0.0 3.9 7.6 0.0 2.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.1 EEA07137.1 - 1.2e-13 51.0 0.1 6.3e-13 48.7 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEA07137.1 - 5.3e-13 49.3 0.0 1.4e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EEA07137.1 - 2.8e-12 46.4 0.0 8.7e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EEA07137.1 - 9.5e-12 44.3 0.1 1.4e-10 40.5 0.0 2.0 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEA07137.1 - 4.9e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA07137.1 - 5.2e-06 26.1 0.0 8.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA07137.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEA07137.1 - 6.1e-05 22.9 0.0 0.00028 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA07137.1 - 0.00012 21.8 0.1 0.00098 18.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EEA07137.1 - 0.00038 20.0 0.1 0.0027 17.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EEA07137.1 - 0.00071 18.6 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EEA07137.1 - 0.00093 18.8 0.1 0.004 16.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain PIF1 PF05970.9 EEA07137.1 - 0.002 17.1 0.1 0.0077 15.2 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EEA07137.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EEA07137.1 - 0.0095 15.5 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EEA07137.1 - 0.014 14.8 0.2 0.28 10.6 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EEA07137.1 - 0.014 16.1 0.0 0.032 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEA07137.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EEA07137.1 - 0.03 13.5 0.1 0.07 12.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEA07137.1 - 0.034 14.3 0.2 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EEA07137.1 - 0.04 14.2 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA07137.1 - 0.056 13.7 0.1 2.8 8.2 0.0 2.5 1 1 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.4 EEA07137.1 - 0.059 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EEA07137.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA07137.1 - 0.066 12.6 0.2 0.39 10.1 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EEA07137.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EEA07137.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 EEA07137.1 - 0.082 13.2 0.3 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EEA07137.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EEA07137.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EEA07137.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Delta_lysin PF05372.6 EEA07137.1 - 2.9 7.3 5.5 0.53 9.6 0.2 2.5 2 0 0 2 2 2 0 Delta lysin family Pkinase PF00069.20 EEA07138.1 - 1.9e-12 46.8 0.0 4.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Bromodomain PF00439.20 EEA07139.1 - 6.5e-22 77.2 2.9 8.5e-22 76.8 0.6 2.3 3 0 0 3 3 3 1 Bromodomain Acetyltransf_1 PF00583.19 EEA07139.1 - 6.4e-11 42.1 0.3 1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA07139.1 - 4.5e-10 39.5 1.7 1e-09 38.4 1.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA07139.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA07139.1 - 0.00073 19.2 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEA07139.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA07139.1 - 0.044 13.9 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DeoC PF01791.4 EEA07140.1 - 4.8e-09 35.8 1.5 3.1e-08 33.2 1.0 2.0 1 1 0 1 1 1 1 DeoC/LacD family aldolase LNS2 PF08235.8 EEA07141.1 - 2.7e-64 215.4 0.0 4.4e-64 214.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EEA07141.1 - 1.7e-34 117.7 0.0 3.9e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.1 EEA07141.1 - 0.027 14.3 0.0 0.82 9.5 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EEA07141.1 - 0.039 13.3 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ARPC4 PF05856.7 EEA07142.1 - 2.8e-43 147.2 1.6 4.2e-43 146.6 1.1 1.3 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Pkinase PF00069.20 EEA07143.1 - 2.4e-48 164.5 0.0 2.3e-35 122.0 0.0 2.6 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07143.1 - 2.3e-24 85.8 0.0 4.3e-16 58.7 0.0 3.6 2 1 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_2 PF00152.15 EEA07143.1 - 0.008 14.9 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RWD PF05773.17 EEA07143.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 RWD domain Peptidase_M54 PF07998.6 EEA07144.1 - 1.6e-15 57.4 0.4 3.1e-15 56.4 0.2 1.3 1 1 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.19 EEA07144.1 - 0.0085 15.8 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 1 Matrixin DUF2268 PF10026.4 EEA07144.1 - 0.041 13.2 0.1 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CBF PF03914.12 EEA07145.1 - 4.9e-16 58.6 2.8 1.1e-15 57.5 1.9 1.6 1 0 0 1 1 1 1 CBF/Mak21 family AAA_18 PF13238.1 EEA07146.1 - 1.2e-26 93.5 0.5 1.6e-26 93.1 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA07146.1 - 2.9e-11 44.2 0.2 4e-11 43.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA07146.1 - 8.3e-06 25.7 0.0 5.8e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA07146.1 - 9.3e-05 22.5 0.0 0.00032 20.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EEA07146.1 - 0.0001 21.5 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.24 EEA07146.1 - 0.00012 22.2 0.9 0.00028 21.0 0.6 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEA07146.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA07146.1 - 0.00019 21.1 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA07146.1 - 0.0016 17.5 0.0 0.0037 16.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EEA07146.1 - 0.0072 16.3 0.4 0.019 14.9 0.2 1.7 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEA07146.1 - 0.0092 15.4 0.4 0.17 11.2 0.2 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEA07146.1 - 0.0096 15.6 0.2 0.024 14.3 0.2 1.6 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EEA07146.1 - 0.011 15.3 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase dNK PF01712.14 EEA07146.1 - 0.016 15.1 0.6 0.025 14.4 0.3 1.6 1 1 0 1 1 1 0 Deoxynucleoside kinase Parvo_NS1 PF01057.12 EEA07146.1 - 0.025 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EEA07146.1 - 0.036 14.2 1.3 0.094 12.9 0.2 2.1 2 2 0 2 2 2 0 RNA helicase GvpD PF07088.6 EEA07146.1 - 0.039 12.2 0.1 0.066 11.5 0.1 1.3 1 1 0 1 1 1 0 GvpD gas vesicle protein DUF2075 PF09848.4 EEA07146.1 - 0.044 12.7 0.0 0.068 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ferritin PF00210.19 EEA07146.1 - 0.045 13.5 0.2 0.098 12.4 0.0 1.5 2 0 0 2 2 2 0 Ferritin-like domain SKI PF01202.17 EEA07146.1 - 0.047 13.5 1.1 1.1 9.1 0.7 2.3 1 1 0 1 1 1 0 Shikimate kinase AAA_14 PF13173.1 EEA07146.1 - 0.058 13.3 1.0 0.084 12.7 0.4 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEA07146.1 - 0.074 12.7 1.4 0.091 12.4 0.3 1.7 2 0 0 2 2 1 0 NTPase Mg_chelatase PF01078.16 EEA07146.1 - 0.094 11.8 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EEA07146.1 - 0.16 10.8 0.2 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EEA07146.1 - 0.21 10.7 1.4 0.31 10.1 0.4 1.6 1 1 0 1 1 1 0 KaiC DUF4325 PF14213.1 EEA07146.1 - 0.25 11.0 2.4 0.32 10.6 0.0 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4325) AAA_24 PF13479.1 EEA07146.1 - 0.38 10.3 2.0 0.6 9.6 0.7 1.8 2 0 0 2 2 2 0 AAA domain Ninjurin PF04923.7 EEA07148.1 - 0.017 14.8 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Ninjurin DUF3981 PF13139.1 EEA07148.1 - 0.42 10.6 4.3 0.47 10.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) Med31 PF05669.7 EEA07149.1 - 3.4e-37 126.3 2.4 3.9e-37 126.1 1.7 1.0 1 0 0 1 1 1 1 SOH1 WHIM1 PF15612.1 EEA07149.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 L27_2 PF09045.5 EEA07149.1 - 0.14 11.7 0.2 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 L27_2 TerB-N PF13208.1 EEA07150.1 - 0.022 14.1 2.9 0.053 12.9 0.2 2.5 2 1 1 3 3 3 0 TerB-N DUF745 PF05335.8 EEA07150.1 - 0.33 10.4 12.3 2.9 7.3 6.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CCDC155 PF14662.1 EEA07150.1 - 0.75 9.3 32.8 0.022 14.3 13.9 3.4 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Fzo_mitofusin PF04799.8 EEA07150.1 - 1.8 7.9 12.3 3.5 6.9 0.3 3.4 1 1 2 3 3 3 0 fzo-like conserved region DUF948 PF06103.6 EEA07150.1 - 7.5 6.4 14.5 6.6 6.6 1.0 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4239 PF14023.1 EEA07150.1 - 8.3 5.7 11.0 1.6 8.0 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) tRNA-synt_2d PF01409.15 EEA07151.1 - 7.4e-81 270.9 0.0 1e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EEA07151.1 - 0.00061 18.6 0.9 0.0036 16.1 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) S10_plectin PF03501.10 EEA07151.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Plectin/S10 domain tRNA-synt_2b PF00587.20 EEA07151.1 - 0.0069 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1938 PF09153.5 EEA07151.1 - 0.036 13.8 0.1 1.5 8.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1938) ImpA-rel_N PF06812.7 EEA07152.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 ImpA-related N-terminal Ribosomal_L7Ae PF01248.21 EEA07153.1 - 6.7e-08 31.9 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mito_fiss_reg PF05308.6 EEA07153.1 - 6.5 6.0 9.7 0.97 8.7 2.7 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Diphthamide_syn PF01866.12 EEA07155.1 - 1.2e-11 44.4 6.7 2.6e-06 26.9 0.1 2.7 2 1 1 3 3 3 2 Putative diphthamide synthesis protein Peroxin-22 PF12827.2 EEA07155.1 - 0.055 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family AOX PF01786.12 EEA07157.1 - 1.5e-76 256.4 0.0 1.8e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Ssl1 PF04056.9 EEA07158.1 - 5.8e-35 120.6 0.1 7.9e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EEA07158.1 - 1.4e-07 31.7 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEA07158.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EEA07158.1 - 0.58 9.3 11.2 2.4 7.3 5.9 2.5 2 1 0 2 2 2 0 Transcription factor Tfb4 DUF2321 PF10083.4 EEA07158.1 - 0.6 9.5 0.0 0.6 9.5 0.0 3.1 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) MFS_1 PF07690.11 EEA07159.1 - 1.1e-37 129.6 37.1 1.4e-29 102.8 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA07159.1 - 1.8e-10 40.0 1.9 1.8e-10 40.0 1.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EEA07159.1 - 2.2e-09 36.2 19.1 0.00016 20.1 0.8 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.15 EEA07159.1 - 5.7e-07 27.9 0.0 0.031 12.3 0.0 3.2 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 EEA07159.1 - 0.00027 19.5 8.9 0.00027 19.5 6.2 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EEA07159.1 - 0.0013 18.4 0.6 0.33 10.7 0.0 3.7 3 0 0 3 3 3 1 MFS_1 like family WD40 PF00400.27 EEA07161.1 - 1.2e-16 59.8 16.5 9.1e-07 28.5 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EEA07161.1 - 0.00086 19.0 0.2 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SLH PF00395.15 EEA07161.1 - 0.027 14.2 0.1 0.29 10.8 0.1 2.4 2 0 0 2 2 2 0 S-layer homology domain LisH PF08513.6 EEA07161.1 - 0.06 13.1 0.0 0.25 11.1 0.0 2.1 3 0 0 3 3 3 0 LisH CRM1_C PF08767.6 EEA07163.1 - 7.6e-79 264.9 17.2 7.6e-79 264.9 11.9 4.1 4 0 0 4 4 4 2 CRM1 C terminal Xpo1 PF08389.7 EEA07163.1 - 8e-29 100.4 5.4 8e-29 100.4 3.7 5.0 7 0 0 7 7 7 1 Exportin 1-like protein IBN_N PF03810.14 EEA07163.1 - 2.7e-08 33.5 3.2 1.3e-07 31.4 0.3 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Pkinase PF00069.20 EEA07165.1 - 9e-70 234.7 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07165.1 - 7e-36 123.6 0.0 9.3e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07165.1 - 2e-06 26.9 0.0 3.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEA07165.1 - 0.028 13.2 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EEA07165.1 - 0.036 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Lact-deh-memb PF09330.6 EEA07165.1 - 0.044 13.1 0.3 0.064 12.6 0.2 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Kdo PF06293.9 EEA07165.1 - 0.053 12.5 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEA07166.1 - 8.7e-72 241.3 0.0 1.2e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07166.1 - 3e-34 118.2 0.0 4.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA07166.1 - 0.00039 19.5 0.3 0.0047 16.0 0.1 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA07166.1 - 0.17 11.6 0.1 1.3 8.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family IF-2B PF01008.12 EEA07167.1 - 2.3e-41 141.6 1.5 2.9e-41 141.3 1.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family L_lactis_RepB_C PF06430.7 EEA07167.1 - 0.026 14.5 0.2 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus Utp12 PF04003.7 EEA07167.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family PC_rep PF01851.17 EEA07168.1 - 0.099 12.9 0.2 0.62 10.4 0.0 2.6 2 0 0 2 2 2 0 Proteasome/cyclosome repeat RabGAP-TBC PF00566.13 EEA07169.1 - 1.1e-22 80.6 13.6 1.1e-22 80.6 9.5 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain AP2 PF00847.15 EEA07172.1 - 5.9e-08 32.7 0.2 0.077 13.1 0.0 4.0 3 0 0 3 3 3 2 AP2 domain KH_1 PF00013.24 EEA07175.1 - 0.0004 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEA07175.1 - 0.0012 18.4 0.0 0.0032 17.0 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EEA07175.1 - 0.061 12.9 0.6 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 KH domain PLDc_2 PF13091.1 EEA07176.1 - 1.6e-22 79.5 0.7 1.9e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEA07176.1 - 6.5e-05 22.6 0.8 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EEA07176.1 - 0.035 13.0 0.0 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Tim44 PF04280.10 EEA07177.1 - 1.6e-24 86.5 0.0 1.5e-23 83.4 0.0 2.3 2 1 0 2 2 2 1 Tim44-like domain Peptidase_C54 PF03416.14 EEA07178.1 - 6.1e-47 160.0 1.1 8.7e-47 159.5 0.7 1.2 1 0 0 1 1 1 1 Peptidase family C54 DUF4218 PF13960.1 EEA07179.1 - 0.18 11.2 1.7 6.8 6.1 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4218) LAGLIDADG_1 PF00961.14 EEA07179.1 - 1.1 9.9 8.2 1.2 9.7 1.3 2.7 3 0 0 3 3 3 0 LAGLIDADG endonuclease Pkinase PF00069.20 EEA07180.1 - 1.1e-46 159.0 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07180.1 - 1.8e-45 155.0 0.0 9.2e-45 152.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PROCN PF08083.6 EEA07181.1 - 1.4e-207 689.0 10.7 2.4e-207 688.3 7.4 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EEA07181.1 - 6.9e-125 414.9 0.5 1.5e-124 413.8 0.3 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EEA07181.1 - 2.3e-93 309.8 1.3 4.9e-93 308.7 0.9 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EEA07181.1 - 3.9e-80 266.8 2.7 1e-79 265.4 1.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EEA07181.1 - 1.1e-66 222.6 0.1 2.2e-66 221.6 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EEA07181.1 - 2e-42 142.9 0.6 7.3e-42 141.1 0.4 2.1 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EEA07181.1 - 3.4e-38 130.1 0.7 1.1e-37 128.4 0.0 2.2 2 0 0 2 2 2 1 PROCT (NUC072) domain LRR_9 PF14580.1 EEA07182.1 - 2.7e-31 108.4 0.7 2.7e-31 108.4 0.5 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EEA07182.1 - 1.4e-12 46.9 31.1 9.3e-06 25.1 4.3 5.7 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA07182.1 - 1.5e-10 40.6 5.8 1.5e-10 40.6 4.0 4.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 EEA07182.1 - 0.00039 20.0 17.7 1.2 9.4 0.8 5.9 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EEA07182.1 - 0.0038 17.1 7.2 8.9 7.0 0.3 4.8 4 1 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 EEA07182.1 - 0.0053 16.6 16.2 1.9 8.7 1.1 5.4 4 1 1 5 5 5 2 Leucine Rich repeat Mob_Pre PF01076.14 EEA07182.1 - 0.078 12.6 0.5 0.12 11.9 0.4 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Dynactin_p22 PF07426.6 EEA07183.1 - 0.00057 19.2 0.8 0.0011 18.3 0.6 1.6 1 1 0 1 1 1 1 Dynactin subunit p22 Transposase_22 PF02994.9 EEA07183.1 - 0.0028 16.2 5.4 0.0033 15.9 3.7 1.1 1 0 0 1 1 1 1 L1 transposable element DUF241 PF03087.9 EEA07183.1 - 0.011 15.2 4.9 0.0092 15.4 2.6 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function rve_3 PF13683.1 EEA07183.1 - 0.014 14.9 0.7 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain Rootletin PF15035.1 EEA07183.1 - 0.033 14.1 2.5 0.067 13.1 1.6 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.8 EEA07183.1 - 0.035 14.0 6.4 0.039 13.8 0.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Aida_N PF08910.5 EEA07183.1 - 0.085 13.1 1.2 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Aida N-terminus IncA PF04156.9 EEA07183.1 - 0.22 11.0 4.1 0.63 9.6 2.8 1.6 1 1 0 1 1 1 0 IncA protein DUF2400 PF09674.5 EEA07183.1 - 0.38 10.4 3.0 0.79 9.3 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) MitMem_reg PF13012.1 EEA07183.1 - 0.45 10.6 5.3 2.2 8.4 3.0 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function MutS_IV PF05190.13 EEA07183.1 - 0.88 9.7 5.1 6.7 6.9 1.3 3.1 2 1 1 3 3 3 0 MutS family domain IV Anticodon_1 PF08264.8 EEA07183.1 - 1.2 8.8 6.6 32 4.2 4.6 2.2 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DUF972 PF06156.8 EEA07183.1 - 2.4 8.5 9.7 2.5 8.4 0.4 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) DUF4041 PF13250.1 EEA07183.1 - 3.3 7.3 8.2 6.1 6.4 0.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) FlxA PF14282.1 EEA07183.1 - 3.7 7.5 7.1 1 9.3 1.3 2.2 1 1 1 2 2 2 0 FlxA-like protein Occludin_ELL PF07303.8 EEA07183.1 - 7.3 7.3 8.0 11 6.8 2.1 2.6 1 1 1 2 2 2 0 Occludin homology domain Syntaxin PF00804.20 EEA07183.1 - 7.5 6.7 7.8 9.9e+02 -0.1 5.5 3.1 1 1 0 1 1 1 0 Syntaxin AMP-binding PF00501.23 EEA07184.1 - 8e-23 80.4 0.0 1.2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C2-set PF05790.10 EEA07184.1 - 0.062 13.2 0.2 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 Immunoglobulin C2-set domain DUF3245 PF11595.3 EEA07187.1 - 0.0016 18.7 5.7 0.0016 18.6 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3245) NUFIP1 PF10453.4 EEA07188.1 - 0.00012 21.4 0.1 0.0007 19.0 0.0 2.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2 PF00096.21 EEA07188.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA07188.1 - 1.3 9.5 0.1 1.3 9.5 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger POP1 PF06978.6 EEA07190.1 - 4.1e-39 134.1 10.6 4.1e-39 134.1 7.3 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EEA07190.1 - 1.6e-10 40.6 0.6 1.4e-08 34.4 0.0 3.0 2 1 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.6 EEA07190.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 EEA07191.1 - 1.4e-08 34.3 0.0 3.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 EEA07191.1 - 6.9e-07 29.6 0.4 1.4e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain zf-C2H2_jaz PF12171.3 EEA07192.1 - 0.00034 20.6 1.9 0.00061 19.8 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA07192.1 - 0.0014 18.7 0.6 0.0024 18.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEA07192.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Cullin PF00888.17 EEA07193.1 - 9e-67 225.9 37.3 8.8e-66 222.6 25.8 2.1 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEA07193.1 - 1.1e-10 41.1 0.1 7.2e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2098 PF09871.4 EEA07193.1 - 0.012 15.4 0.4 0.8 9.6 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) TH1 PF04858.8 EEA07194.1 - 2.2e-10 39.3 0.0 7.5e-06 24.3 0.0 4.2 4 0 0 4 4 4 4 TH1 protein TF_Zn_Ribbon PF08271.7 EEA07195.1 - 9.8e-06 24.7 2.1 2.9e-05 23.2 1.5 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EEA07195.1 - 0.058 12.9 6.6 0.15 11.5 4.6 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 EEA07195.1 - 0.1 12.2 5.3 14 5.3 2.9 2.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EEA07195.1 - 0.2 11.1 6.3 0.093 12.2 2.6 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EEA07195.1 - 0.82 9.5 3.8 1.8 8.4 2.6 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Herpes_UL52 PF03121.10 EEA07196.1 - 6.3e-15 54.6 2.2 6.9e-15 54.5 0.2 2.2 3 0 0 3 3 3 1 Herpesviridae UL52/UL70 DNA primase Ank_5 PF13857.1 EEA07197.1 - 2.3e-06 27.6 0.0 0.0044 17.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA07197.1 - 0.00065 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA07197.1 - 0.0036 17.7 0.0 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EEA07197.1 - 0.023 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat TLD PF07534.11 EEA07198.1 - 4.4e-26 91.5 0.0 1.3e-25 90.0 0.0 1.8 1 1 0 1 1 1 1 TLD Hydrolase PF00702.21 EEA07199.1 - 8.7e-13 49.1 0.1 2.1e-11 44.6 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA07199.1 - 9.3e-12 45.5 0.3 5.6e-11 42.9 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA07199.1 - 7.6e-10 38.2 0.0 7.6e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEA07199.1 - 0.00021 21.2 0.1 0.00061 19.7 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA07199.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 2.8 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase TP6A_N PF04406.9 EEA07200.1 - 1.3e-12 47.2 0.5 2.4e-12 46.3 0.4 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EEA07200.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) L27 PF02828.11 EEA07200.1 - 0.0059 16.2 0.0 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 L27 domain CENP-C_C PF11699.3 EEA07201.1 - 0.00012 21.9 0.0 0.00034 20.5 0.0 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like TRAPP PF04051.11 EEA07202.1 - 7.2e-34 116.5 0.0 8.9e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DnaJ PF00226.26 EEA07203.1 - 2.6e-24 84.7 0.1 5.3e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EEA07203.1 - 2.8e-06 26.9 0.0 8.2e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin RGCC PF15151.1 EEA07203.1 - 0.0062 16.9 1.8 0.013 15.9 1.3 1.5 1 0 0 1 1 1 1 Response gene to complement 32 protein family DUF457 PF04307.9 EEA07203.1 - 0.2 10.9 2.6 0.45 9.8 0.8 2.0 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) SPC22 PF04573.7 EEA07204.1 - 4.6e-32 110.6 0.3 5.3e-32 110.4 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit UQ_con PF00179.21 EEA07205.1 - 7e-49 164.8 0.0 8.3e-49 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA07205.1 - 0.00061 19.6 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain DAGK_acc PF00609.14 EEA07209.1 - 1.7e-36 125.7 0.2 1.1e-13 51.6 0.0 3.5 2 1 1 3 3 3 3 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EEA07209.1 - 2.3e-22 78.8 0.0 3.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EEA07209.1 - 2e-11 43.4 25.4 1e-07 31.5 2.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_pol_Rpb1_5 PF04998.12 EEA07210.1 - 2.8e-102 341.7 0.1 4.5e-102 341.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EEA07210.1 - 1.9e-99 333.1 0.0 3.1e-99 332.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EEA07210.1 - 1.3e-68 230.0 0.0 3.5e-68 228.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EEA07210.1 - 9.7e-49 165.6 0.0 1.8e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EEA07210.1 - 5.4e-44 149.7 0.0 1.6e-43 148.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EEA07210.1 - 1.5e-39 134.7 3.0 1.6e-39 134.7 1.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EEA07210.1 - 1.4e-36 124.4 0.1 4.3e-36 122.9 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EEA07210.1 - 6.1e-19 66.3 319.8 0.013 15.5 7.9 23.0 18 2 1 19 19 19 14 RNA polymerase Rpb1 C-terminal repeat Swi3 PF07962.7 EEA07211.1 - 4.9e-05 22.8 0.2 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Kinesin PF00225.18 EEA07213.1 - 3e-104 348.3 4.3 3e-104 348.3 3.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Fib_alpha PF08702.5 EEA07213.1 - 0.39 10.8 20.4 0.092 12.8 10.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Nbl1_Borealin_N PF10444.4 EEA07213.1 - 1.3 8.4 7.6 9.5 5.6 0.7 3.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal RRM_1 PF00076.17 EEA07214.1 - 6.6e-19 67.3 0.7 1.5e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07214.1 - 4.9e-18 64.7 0.6 2e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07214.1 - 2.3e-09 37.0 0.0 4e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 EEA07215.1 - 3.8e-14 52.5 0.4 3.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 EEA07215.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEA07215.1 - 0.073 12.1 0.2 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RabGAP-TBC PF00566.13 EEA07216.1 - 2.6e-49 167.6 3.7 2.6e-49 167.6 2.6 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TFIIS_C PF01096.13 EEA07217.1 - 1.2e-13 50.4 7.1 1.2e-13 50.4 4.9 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EEA07217.1 - 0.031 14.0 13.5 0.58 9.9 2.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EEA07217.1 - 0.24 10.7 5.6 1.4 8.2 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding Terminase_GpA PF05876.7 EEA07217.1 - 0.36 9.1 5.8 1.6 6.9 1.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) ADK_lid PF05191.9 EEA07217.1 - 0.69 9.6 8.4 13 5.5 0.1 3.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid Lar_restr_allev PF14354.1 EEA07217.1 - 1.9 8.8 11.3 1.8 8.9 1.6 3.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar RNA_pol_Rpb1_1 PF04997.7 EEA07217.1 - 2.9 7.0 10.6 2 7.5 0.4 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 Histone PF00125.19 EEA07219.1 - 7.5e-33 112.4 0.4 1.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA07219.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEA07219.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Proteasome PF00227.21 EEA07220.1 - 1.8e-47 161.1 0.6 2.2e-47 160.8 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EEA07220.1 - 0.078 12.2 0.3 0.078 12.2 0.2 1.9 2 0 0 2 2 2 0 Proteasome beta subunits C terminal NUMOD4 PF07463.6 EEA07220.1 - 0.28 11.1 1.2 0.41 10.5 0.2 1.7 2 0 0 2 2 2 0 NUMOD4 motif TPR_11 PF13414.1 EEA07221.1 - 4.3e-19 67.9 12.2 2.2e-08 33.5 1.3 4.7 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.1 EEA07221.1 - 2.3e-15 56.6 1.0 2.6e-05 24.4 0.1 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07221.1 - 3.2e-14 51.6 13.0 0.0039 17.0 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEA07221.1 - 1.3e-12 48.0 0.0 4.4e-06 27.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA07221.1 - 1.2e-09 37.3 15.8 0.0018 17.8 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA07221.1 - 9.9e-09 35.2 15.9 0.0014 18.6 0.8 5.0 2 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEA07221.1 - 6.3e-08 32.2 4.0 0.012 15.7 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07221.1 - 1.1e-06 28.6 0.0 2 9.2 0.0 5.6 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA07221.1 - 2.8e-06 26.6 21.0 0.065 13.0 0.2 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07221.1 - 3.2e-06 26.9 12.9 0.0062 16.4 1.2 5.3 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA07221.1 - 5e-06 26.6 0.3 0.19 12.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA07221.1 - 8.7e-05 22.0 2.0 0.19 11.5 0.0 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA07221.1 - 0.0008 19.2 0.0 0.032 14.0 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA07221.1 - 0.011 15.6 2.4 32 4.6 0.2 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat UPF0004 PF00919.15 EEA07221.1 - 0.1 12.4 0.2 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 Myb_DNA-bind_6 PF13921.1 EEA07222.1 - 5.2e-13 48.8 2.0 1.7e-11 44.0 0.3 4.8 4 2 1 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA07222.1 - 5.7e-11 42.3 3.8 1.6e-09 37.6 0.3 3.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain DUF3441 PF11923.3 EEA07222.1 - 0.0089 15.5 0.0 0.031 13.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) Myb_DNA-bind_5 PF13873.1 EEA07222.1 - 0.063 13.1 7.0 5.1 7.0 0.3 4.8 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain HTH_Tnp_1 PF01527.15 EEA07222.1 - 0.085 12.8 0.2 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Transposase SopA_C PF13979.1 EEA07222.1 - 0.19 11.3 3.2 0.38 10.3 2.2 1.5 1 0 0 1 1 1 0 SopA-like catalytic domain Nup35_RRM_2 PF14605.1 EEA07223.1 - 7.9e-17 60.7 0.0 1.2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Thioredoxin PF00085.15 EEA07224.1 - 0.00063 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Fe_hyd_SSU PF02256.12 EEA07224.1 - 0.043 13.8 0.4 0.39 10.7 0.0 2.6 2 0 0 2 2 2 0 Iron hydrogenase small subunit MFS_1 PF07690.11 EEA07225.1 - 1.6e-09 36.9 14.6 1.9e-09 36.7 9.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EEA07225.1 - 0.33 9.3 19.8 1.4 7.3 3.0 2.6 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like RL11D PF11088.3 EEA07226.1 - 1.3 8.8 6.8 0.52 10.1 0.4 2.7 1 1 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF1233 PF06806.7 EEA07227.1 - 0.071 12.6 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative excisionase (DUF1233) eIF3_subunit PF08597.5 EEA07229.1 - 0.0011 18.6 12.2 0.002 17.7 8.5 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4163 PF13739.1 EEA07229.1 - 7.2 7.4 10.1 1 10.1 1.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4163) UbiA PF01040.13 EEA07230.1 - 2.3e-25 89.3 8.4 2.7e-25 89.0 5.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GYF PF02213.11 EEA07231.1 - 3.8e-13 48.8 1.1 1.8e-12 46.6 0.1 2.6 2 0 0 2 2 2 1 GYF domain IQ PF00612.22 EEA07231.1 - 0.07 12.8 0.4 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_S13 PF00416.17 EEA07232.1 - 2.4e-40 137.2 3.5 2.9e-40 137.0 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEA07232.1 - 0.023 13.2 0.0 0.033 12.7 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) CEP1-DNA_bind PF09287.5 EEA07232.1 - 0.13 11.7 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 CEP-1, DNA binding CorA PF01544.13 EEA07233.1 - 8.8e-06 24.9 2.1 1.9e-05 23.8 1.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ufd2P_core PF10408.4 EEA07234.1 - 2.2e-128 429.2 36.6 2.8e-128 428.9 25.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EEA07234.1 - 2.1e-23 82.0 2.0 2.1e-23 82.0 1.4 2.8 3 0 0 3 3 3 1 U-box domain SLEI_Leptospira PF07620.6 EEA07235.1 - 0.02 14.6 0.9 0.055 13.2 0.6 1.7 1 0 0 1 1 1 0 SLEI NAGidase PF07555.8 EEA07235.1 - 0.11 11.4 0.1 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase SMK-1 PF04802.10 EEA07236.1 - 8.3e-27 93.9 7.1 2.2e-26 92.5 4.9 1.8 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SET PF00856.23 EEA07237.1 - 3.6e-26 92.3 0.1 2.4e-25 89.7 0.1 2.3 1 1 0 1 1 1 1 SET domain PHD PF00628.24 EEA07237.1 - 6.6e-07 28.9 7.3 6.6e-07 28.9 5.1 2.8 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EEA07237.1 - 0.0016 17.7 3.4 0.0016 17.7 2.4 2.5 3 0 0 3 3 3 1 PHD-finger Peptidase_M24 PF00557.19 EEA07238.1 - 1e-24 87.2 0.3 1.3e-24 86.8 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Prok-E2_B PF14461.1 EEA07238.1 - 0.15 11.7 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B TRP PF06011.7 EEA07239.1 - 0.054 12.0 0.6 0.067 11.7 0.4 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4051 PF13260.1 EEA07239.1 - 0.083 12.2 3.1 0.15 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Chordopox_A13L PF05961.6 EEA07239.1 - 0.14 12.0 0.9 0.22 11.5 0.6 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Herpes_UL73 PF03554.8 EEA07239.1 - 0.15 11.9 10.5 0.2 11.4 7.3 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein adh_short PF00106.20 EEA07240.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA07240.1 - 1.3e-05 24.9 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA07240.1 - 0.0035 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA07240.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Nucleoporin2 PF04096.9 EEA07241.1 - 8.8e-37 126.0 0.0 7.3e-36 123.0 0.0 2.6 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nup96 PF12110.3 EEA07241.1 - 1.1e-21 77.2 6.7 2e-21 76.3 4.7 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.1 EEA07241.1 - 0.0074 16.4 275.7 0.5 10.6 27.1 8.7 2 2 3 5 5 5 2 Nucleoporin FG repeat region Rrp15p PF07890.7 EEA07242.1 - 4.1e-10 39.8 7.4 1e-09 38.5 5.2 1.6 1 1 1 2 2 2 1 Rrp15p rRNA_methylase PF06962.7 EEA07242.1 - 0.017 14.8 0.7 0.023 14.4 0.5 1.3 1 0 0 1 1 1 0 Putative rRNA methylase DUF4404 PF14357.1 EEA07242.1 - 0.4 11.1 2.9 0.4 11.1 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3335 PF11814.3 EEA07242.1 - 0.62 9.1 3.7 0.39 9.8 0.9 1.7 1 1 1 2 2 2 0 Peptidase_C39 like family ETRAMP PF09716.5 EEA07242.1 - 4 7.4 11.1 0.47 10.4 0.8 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Prenyltrans PF00432.16 EEA07243.1 - 3e-21 74.6 1.0 1e-11 44.2 0.0 5.1 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA07243.1 - 6.3e-14 52.3 0.0 1.8e-05 25.1 0.0 2.7 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA07243.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 Prenyltransferase-like zf-CSL PF05207.8 EEA07244.1 - 1.6e-13 49.9 0.8 2e-13 49.5 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger E7 PF00527.13 EEA07244.1 - 0.0049 16.9 0.4 0.0091 16.1 0.3 1.4 1 1 0 1 1 1 1 E7 protein, Early protein DEAD PF00270.24 EEA07245.1 - 5.2e-45 152.9 0.4 4.6e-44 149.8 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA07245.1 - 5.3e-22 77.4 0.1 1.6e-21 75.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EEA07245.1 - 0.00052 19.7 1.4 0.0015 18.3 1.0 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Gaa1 PF04114.9 EEA07247.1 - 6.4e-20 71.3 8.5 1e-12 47.5 0.1 3.0 2 2 0 2 2 2 2 Gaa1-like, GPI transamidase component PDEase_I PF00233.14 EEA07248.1 - 6.7e-56 189.6 0.0 1.1e-55 188.9 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RRM_1 PF00076.17 EEA07249.1 - 1.6e-16 59.6 0.0 2.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07249.1 - 1.1e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07249.1 - 9.7e-10 38.1 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EEA07250.1 - 9.3e-17 61.4 0.0 3e-14 53.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA07250.1 - 1.6e-06 28.2 0.0 0.003 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEA07250.1 - 1.3e-05 25.9 0.4 0.0099 16.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EEA07250.1 - 2.3e-05 24.2 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA07250.1 - 3.4e-05 23.5 0.0 0.4 10.3 0.0 2.8 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 EEA07250.1 - 4.1e-05 23.7 0.2 0.059 13.5 0.2 3.3 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EEA07250.1 - 7.5e-05 21.8 0.1 0.31 9.9 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.17 EEA07250.1 - 0.00019 21.5 0.0 0.93 9.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 EEA07250.1 - 0.00023 21.0 8.3 0.063 13.1 0.1 3.8 3 0 0 3 3 3 2 AAA domain UPF0079 PF02367.12 EEA07250.1 - 0.0005 19.7 0.1 0.068 12.7 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EEA07250.1 - 0.00082 19.6 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 EEA07250.1 - 0.0013 18.4 0.3 0.85 9.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EEA07250.1 - 0.0028 16.5 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EEA07250.1 - 0.0042 16.6 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EEA07250.1 - 0.0098 16.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF2791 PF10923.3 EEA07250.1 - 0.013 14.1 0.0 0.28 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_18 PF13238.1 EEA07250.1 - 0.016 15.5 0.5 1.7 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EEA07250.1 - 0.016 14.3 0.0 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EEA07250.1 - 0.018 14.8 0.0 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 EEA07250.1 - 0.026 13.4 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEA07250.1 - 0.029 14.1 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EEA07250.1 - 0.031 13.7 1.3 1.2 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain cobW PF02492.14 EEA07250.1 - 0.045 13.1 0.4 4.9 6.5 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEA07250.1 - 0.051 13.2 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EEA07250.1 - 0.056 12.9 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA07250.1 - 0.11 12.0 0.0 6.3 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA07250.1 - 0.19 11.1 0.4 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 EEA07253.1 - 1.6e-14 53.1 1.6 0.0022 17.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat UTP15_C PF09384.5 EEA07253.1 - 1.7e-14 53.7 0.6 4.8e-14 52.2 0.4 1.7 1 1 0 1 1 1 1 UTP15 C terminal CPSF_A PF03178.10 EEA07253.1 - 4.2e-05 22.7 0.2 0.00091 18.4 0.0 2.7 2 1 0 2 2 2 1 CPSF A subunit region DUF2113 PF09886.4 EEA07254.1 - 0.077 12.1 0.0 5 6.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2113) SAC3_GANP PF03399.11 EEA07255.1 - 7.9e-12 45.1 6.6 1.1e-11 44.7 4.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF1514 PF07438.6 EEA07255.1 - 0.13 12.1 3.9 3.9 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) PARG_cat PF05028.9 EEA07256.1 - 0.24 10.6 1.1 0.41 9.8 0.7 1.4 1 1 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Ribosomal_L37ae PF01780.14 EEA07257.1 - 2e-36 123.7 8.8 2.4e-36 123.4 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EEA07257.1 - 0.0067 16.2 4.9 0.011 15.5 3.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EEA07257.1 - 0.077 12.7 2.7 0.51 10.1 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger A2L_zn_ribbon PF08792.5 EEA07257.1 - 0.2 11.1 3.8 0.79 9.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain UMP1 PF05348.6 EEA07258.1 - 6.2e-15 55.2 0.0 7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SynMuv_product PF06047.6 EEA07259.1 - 6.7e-46 154.3 5.5 1.2e-45 153.5 3.8 1.3 1 0 0 1 1 1 1 Ras-induced vulval development antagonist Rep_3 PF01051.16 EEA07259.1 - 0.029 13.9 0.3 0.029 13.9 0.2 1.6 2 0 0 2 2 2 0 Initiator Replication protein Pinin_SDK_memA PF04696.8 EEA07259.1 - 0.033 13.8 4.4 0.059 12.9 3.0 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region UQ_con PF00179.21 EEA07260.1 - 2e-48 163.3 0.1 2.3e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA07260.1 - 0.0011 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEA07260.1 - 0.0064 16.1 0.1 0.012 15.2 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EEA07260.1 - 0.045 13.6 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 RWD domain Rep_fac-A_C PF08646.5 EEA07261.1 - 4.9e-19 68.4 1.7 1.3e-18 67.0 1.1 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EEA07261.1 - 1.7e-11 43.8 0.3 3.5e-08 33.1 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EEA07261.1 - 0.00089 19.2 0.3 0.0033 17.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF223 DZR PF12773.2 EEA07261.1 - 0.026 14.3 1.1 0.051 13.3 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon Proteasome PF00227.21 EEA07262.1 - 2.1e-46 157.5 0.1 2.9e-46 157.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA07262.1 - 2.8e-13 48.8 0.1 5.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lipoprotein_17 PF04200.7 EEA07262.1 - 0.11 12.7 0.2 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 Lipoprotein associated domain Asp_protease PF09668.5 EEA07263.1 - 1.3e-55 186.2 0.9 2e-55 185.6 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EEA07263.1 - 5.2e-10 39.7 0.2 1.5e-09 38.2 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EEA07263.1 - 5.6e-10 38.4 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEA07263.1 - 1.3e-08 34.4 0.3 2.5e-08 33.5 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.15 EEA07263.1 - 2.4e-06 27.3 0.1 1.5e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEA07263.1 - 0.00034 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EEA07263.1 - 0.00055 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.3 EEA07263.1 - 0.0078 16.4 0.2 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Rad60-SLD PF11976.3 EEA07263.1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sda PF08970.5 EEA07263.1 - 0.019 14.4 0.1 8.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Sporulation inhibitor A YflT PF11181.3 EEA07263.1 - 0.088 12.9 1.1 5.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Heat induced stress protein YflT DUF2407 PF10302.4 EEA07263.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ketoacyl-synt PF00109.21 EEA07264.1 - 1.3e-239 791.4 1.4 8.7e-82 274.3 0.2 3.4 3 0 0 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA07264.1 - 7.3e-167 550.3 0.0 7.3e-58 195.2 0.0 4.2 5 0 0 5 5 4 3 KR domain Acyl_transf_1 PF00698.16 EEA07264.1 - 4.2e-143 476.4 0.0 2.8e-57 194.4 0.0 3.4 3 0 0 3 3 3 3 Acyl transferase domain adh_short PF00106.20 EEA07264.1 - 7.5e-129 426.1 0.8 1.5e-44 151.8 0.0 4.5 6 0 0 6 6 3 3 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA07264.1 - 2.1e-123 405.0 9.7 3.8e-42 142.8 1.0 3.6 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EEA07264.1 - 3.9e-71 239.6 0.0 1.1e-28 100.2 0.0 4.5 3 2 0 3 3 3 3 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 EEA07264.1 - 5.5e-61 205.6 0.0 1.6e-53 181.1 0.0 5.0 5 0 0 5 5 5 3 Male sterility protein AMP-binding PF00501.23 EEA07264.1 - 1.1e-60 205.2 0.0 4.1e-35 120.9 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme ADH_zinc_N PF00107.21 EEA07264.1 - 7e-58 193.7 0.0 1.8e-17 63.1 0.0 3.9 3 0 0 3 3 3 3 Zinc-binding dehydrogenase PP-binding PF00550.20 EEA07264.1 - 3.1e-51 171.4 3.0 5.7e-13 48.9 0.0 4.7 4 0 0 4 4 4 4 Phosphopantetheine attachment site Epimerase PF01370.16 EEA07264.1 - 4.6e-28 98.2 0.0 1.7e-07 30.9 0.0 5.2 4 0 0 4 4 4 4 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EEA07264.1 - 2e-18 66.1 16.8 9.2e-06 25.3 0.1 6.1 5 3 0 8 8 8 3 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA07264.1 - 6.3e-16 59.4 0.0 0.0033 18.2 0.0 3.9 3 0 0 3 3 3 3 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 EEA07264.1 - 3.6e-15 55.6 0.4 0.0022 16.9 0.0 4.1 4 0 0 4 4 4 3 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 EEA07264.1 - 2.7e-07 29.8 15.3 0.0034 16.4 0.1 3.9 4 0 0 4 4 4 3 Thiolase, N-terminal domain 2-Hacid_dh_C PF02826.14 EEA07264.1 - 4e-05 22.8 2.6 5.4 6.1 0.0 5.0 4 3 0 4 4 4 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEA07264.1 - 0.00071 19.6 0.6 4.6 7.3 0.0 4.0 4 0 0 4 4 3 2 Shikimate / quinate 5-dehydrogenase AMP-binding_C_2 PF14535.1 EEA07264.1 - 0.00098 19.1 0.0 0.0035 17.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage-scaffold PF09306.5 EEA07264.1 - 7.9 5.5 0.0 30 3.6 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage, scaffolding protein Proteasome PF00227.21 EEA07265.1 - 1.9e-35 121.8 0.6 2.4e-35 121.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA07265.1 - 6.8e-13 47.6 0.0 1.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SprT-like PF10263.4 EEA07266.1 - 2.2e-36 124.9 0.1 2.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family DUF4368 PF14287.1 EEA07266.1 - 0.8 9.5 3.0 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4368) PTPLA PF04387.9 EEA07267.1 - 2.2e-49 167.0 11.2 3.4e-49 166.4 7.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Myosin_head PF00063.16 EEA07270.1 - 3.3e-31 108.1 2.5 2.2e-26 92.1 0.0 3.3 2 2 0 2 2 2 2 Myosin head (motor domain) RCC1 PF00415.13 EEA07270.1 - 7.5e-30 102.9 5.9 4.2e-10 39.6 0.1 6.7 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 EEA07270.1 - 6.9e-12 43.8 32.4 0.0019 17.6 0.4 7.8 7 0 0 7 7 7 5 IQ calmodulin-binding motif RCC1_2 PF13540.1 EEA07270.1 - 3.5e-10 39.2 26.3 0.00012 21.5 0.2 6.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Nop PF01798.13 EEA07272.1 - 8.6e-59 197.1 0.7 1.6e-58 196.2 0.5 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA07272.1 - 7.4e-27 92.9 0.1 1.8e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEA07272.1 - 5.1e-20 71.3 0.3 1.1e-19 70.2 0.2 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain KxDL PF10241.4 EEA07272.1 - 0.14 12.0 2.1 3.4 7.6 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein HAP PF03866.8 EEA07272.1 - 0.16 11.7 0.1 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) PS_Dcarbxylase PF02666.10 EEA07273.1 - 3.5e-48 163.6 0.0 4.3e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 EEA07273.1 - 0.057 13.4 0.1 19 5.3 0.0 2.6 2 1 0 2 2 2 0 Peptidase family M23 Ribosomal_S2 PF00318.15 EEA07274.1 - 2.5e-40 137.9 1.8 3.8e-20 72.0 0.2 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Ion_trans_2 PF07885.11 EEA07275.1 - 2.7e-11 43.0 10.4 1e-10 41.1 7.2 2.0 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 EEA07275.1 - 3.4e-11 42.9 0.6 2.2e-07 30.7 0.2 3.7 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Lig_chan PF00060.21 EEA07275.1 - 0.065 12.9 2.7 0.22 11.2 1.9 1.8 1 0 0 1 1 1 0 Ligand-gated ion channel F-actin_cap_A PF01267.12 EEA07276.1 - 3.1e-18 65.8 1.9 1.2e-17 63.8 0.3 2.2 2 0 0 2 2 2 1 F-actin capping protein alpha subunit Holin_LLH PF09682.5 EEA07276.1 - 0.13 12.3 0.1 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) zf-C2HC_2 PF13913.1 EEA07277.1 - 0.18 11.5 1.6 0.31 10.7 1.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-RING_2 PF13639.1 EEA07279.1 - 5.7e-13 48.4 6.5 5.7e-13 48.4 4.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_3 PF14369.1 EEA07279.1 - 1e-10 41.3 3.6 1e-10 41.3 2.5 2.7 3 0 0 3 3 2 1 zinc-finger zf-rbx1 PF12678.2 EEA07279.1 - 9.8e-09 35.2 1.7 9.8e-09 35.2 1.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA07279.1 - 2.6e-05 23.8 5.8 2.6e-05 23.8 4.0 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EEA07279.1 - 0.00016 21.5 1.7 0.00049 19.9 1.2 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 EEA07279.1 - 0.00057 19.5 4.3 0.00057 19.5 3.0 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA07279.1 - 0.00069 19.4 3.7 0.0018 18.0 2.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEA07279.1 - 0.0012 18.7 5.9 0.0012 18.7 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07279.1 - 0.0019 17.8 1.8 0.0019 17.8 1.2 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 EEA07279.1 - 1.9 8.7 7.6 3.4 7.9 0.7 2.5 2 0 0 2 2 2 0 CHY zinc finger Tape_meas_lam_C PF09718.5 EEA07279.1 - 2.7 7.9 5.2 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zinc-ribbons_6 PF07191.7 EEA07279.1 - 6.3 6.6 6.7 22 4.9 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbons 2OG-FeII_Oxy_3 PF13640.1 EEA07280.1 - 3.5e-08 33.8 0.0 5.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEA07280.1 - 8.6e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEA07280.1 - 0.0092 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Propep_M14 PF02244.11 EEA07280.1 - 0.064 12.9 0.2 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide PolyA_pol PF01743.15 EEA07281.1 - 8.7e-24 84.1 0.3 7.4e-23 81.1 0.2 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEA07281.1 - 0.045 13.3 0.2 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Choline_kinase PF01633.15 EEA07282.1 - 1.7e-43 148.6 0.0 2.6e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEA07282.1 - 1.3e-07 31.6 0.0 2.5e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEA07282.1 - 0.011 14.9 0.3 0.015 14.5 0.2 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase VHP PF02209.14 EEA07282.1 - 0.019 14.6 0.7 0.044 13.4 0.5 1.6 1 0 0 1 1 1 0 Villin headpiece domain PP2C PF00481.16 EEA07283.1 - 4.9e-62 209.6 0.1 3.2e-50 170.9 0.1 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C RNase_P_Rpp14 PF01900.14 EEA07284.1 - 3.3e-14 52.6 0.2 5.3e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Gar1 PF04410.9 EEA07284.1 - 0.25 10.7 0.9 0.42 10.0 0.6 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region EF-hand_8 PF13833.1 EEA07285.1 - 0.064 12.8 0.1 0.25 10.9 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair WD40 PF00400.27 EEA07286.1 - 7e-11 41.5 0.4 0.085 12.7 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2654 PF10849.3 EEA07287.1 - 0.013 15.1 0.9 0.62 9.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) HUN PF08729.5 EEA07287.1 - 0.014 15.2 14.5 0.11 12.3 10.0 2.6 1 1 0 1 1 1 0 HPC2 and ubinuclein domain AP2 PF00847.15 EEA07288.1 - 0.82 9.8 2.8 3.9 7.6 0.1 2.9 2 1 0 2 2 2 0 AP2 domain SPDY PF03771.11 EEA07288.1 - 2.5 7.6 5.3 19 4.8 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) ATG16 PF08614.6 EEA07289.1 - 0.0088 15.8 10.2 0.0088 15.8 7.0 1.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Nbl1_Borealin_N PF10444.4 EEA07289.1 - 0.051 12.9 2.4 0.093 12.1 0.1 2.7 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal Med2 PF11214.3 EEA07289.1 - 0.12 12.3 7.9 0.53 10.3 2.2 2.1 1 1 1 2 2 2 0 Mediator complex subunit 2 Spc7 PF08317.6 EEA07289.1 - 0.24 10.0 9.4 0.31 9.6 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tweety PF04906.8 EEA07289.1 - 0.33 9.3 1.8 0.36 9.1 0.8 1.3 1 1 0 1 1 1 0 Tweety Mst1_SARAH PF11629.3 EEA07289.1 - 0.79 9.5 6.3 12 5.8 0.1 3.2 3 1 0 3 3 3 0 C terminal SARAH domain of Mst1 Rep_fac_C PF08542.6 EEA07289.1 - 0.83 9.6 5.2 8.7 6.4 0.1 2.6 1 1 2 3 3 3 0 Replication factor C C-terminal domain Fib_alpha PF08702.5 EEA07289.1 - 6.5 6.8 9.0 2 8.5 2.3 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Imm28 PF15574.1 EEA07290.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 28 SAP30_Sin3_bdg PF13867.1 EEA07290.1 - 0.14 12.0 0.2 0.42 10.5 0.1 1.9 1 1 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 NUDIX PF00293.23 EEA07291.1 - 1.8e-13 50.2 0.0 2.2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 EEA07291.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 DBC1 CBM_14 PF01607.19 EEA07291.1 - 0.086 12.7 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain TCTP PF00838.12 EEA07292.1 - 3e-35 121.6 0.8 3.5e-35 121.4 0.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein NfeD PF01957.13 EEA07293.1 - 0.48 10.5 2.4 0.55 10.3 0.4 1.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding OAD_gamma PF04277.8 EEA07293.1 - 2.9 8.3 7.8 5.4 7.4 0.5 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Claudin_3 PF06653.6 EEA07293.1 - 3 7.5 25.7 0.049 13.3 11.4 2.4 2 1 1 3 3 3 0 Tight junction protein, Claudin-like FtsX PF02687.16 EEA07293.1 - 3.2 7.5 19.8 2.5 7.8 6.9 3.0 3 0 0 3 3 3 0 FtsX-like permease family Vpu PF00558.14 EEA07293.1 - 4.7 6.8 8.0 0.84 9.2 0.2 2.8 2 0 0 2 2 2 0 Vpu protein PRP38 PF03371.10 EEA07294.1 - 7.7e-52 175.3 0.8 1e-51 174.9 0.5 1.1 1 0 0 1 1 1 1 PRP38 family SART-1 PF03343.8 EEA07294.1 - 0.0092 14.3 0.3 0.014 13.7 0.2 1.3 1 0 0 1 1 1 1 SART-1 family Acetyltransf_1 PF00583.19 EEA07296.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA07296.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4635 PF15466.1 EEA07296.1 - 0.0015 17.8 0.1 0.0063 15.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4635) Acetyltransf_4 PF13420.1 EEA07296.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA07296.1 - 0.04 14.0 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 EEA07297.1 - 8.5e-08 31.8 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA07297.1 - 1.7e-05 24.2 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEA07297.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family MtrG PF04210.8 EEA07297.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CDKN3 PF05706.7 EEA07297.1 - 0.021 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RRM_6 PF14259.1 EEA07298.1 - 2.2e-17 62.7 0.2 6.2e-13 48.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA07298.1 - 5.1e-16 58.0 0.2 1.1e-11 44.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07298.1 - 3e-05 23.7 0.2 0.00019 21.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EEA07298.1 - 0.0057 16.0 1.5 0.017 14.5 1.0 1.8 1 0 0 1 1 1 1 Lsm interaction motif UN_NPL4 PF11543.3 EEA07298.1 - 0.69 10.2 4.8 47 4.3 0.0 3.8 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 TFIIS_C PF01096.13 EEA07299.1 - 8.3e-08 31.7 13.3 9.8e-08 31.5 0.4 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEA07299.1 - 3.3e-07 29.8 7.2 3.3e-07 29.8 5.0 3.2 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EEA07299.1 - 0.00058 19.6 7.2 0.056 13.2 0.8 2.9 2 1 0 2 2 2 2 Double zinc ribbon A2L_zn_ribbon PF08792.5 EEA07299.1 - 0.018 14.4 0.7 0.5 9.8 0.0 4.2 5 0 0 5 5 5 0 A2L zinc ribbon domain DUF3795 PF12675.2 EEA07299.1 - 0.043 13.9 5.2 0.44 10.7 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) zf-B_box PF00643.19 EEA07299.1 - 0.23 11.3 9.0 8.9 6.2 0.3 4.0 4 0 0 4 4 4 0 B-box zinc finger RecR PF02132.10 EEA07299.1 - 0.49 9.8 0.2 0.49 9.8 0.1 2.9 4 0 0 4 4 3 0 RecR protein Elf1 PF05129.8 EEA07299.1 - 0.98 9.1 4.7 0.82 9.4 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like FYVE_2 PF02318.11 EEA07299.1 - 1.8 8.4 5.4 7.1 6.5 0.7 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2296 PF10058.4 EEA07299.1 - 4.1 7.2 12.3 3.3 7.5 0.1 3.5 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 EEA07299.1 - 6.4 6.6 12.8 25 4.7 0.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EEA07299.1 - 9.2 5.6 15.1 13 5.0 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain EGF_CA PF07645.10 EEA07300.1 - 1.3e-61 204.3 133.4 5.8e-12 45.4 5.1 10.2 10 1 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.2 EEA07300.1 - 5.4e-52 172.9 63.8 3.4e-10 39.3 1.1 9.5 9 0 0 9 9 9 8 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EEA07300.1 - 1.1e-30 105.4 125.3 1.6e-10 40.8 5.3 9.5 9 0 0 9 9 9 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EEA07300.1 - 1.1e-13 50.8 108.3 0.00027 20.8 3.2 10.9 8 2 1 9 9 9 7 EGF domain EGF PF00008.22 EEA07300.1 - 4.9e-13 48.7 111.8 1.4e-05 24.9 4.7 10.8 9 2 1 10 10 10 7 EGF-like domain hEGF PF12661.2 EEA07300.1 - 0.17 12.0 48.4 0.071 13.2 0.8 8.8 8 0 0 8 8 8 0 Human growth factor-like EGF CK_II_beta PF01214.13 EEA07301.1 - 9.5e-66 220.8 0.0 1.9e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HMG14_17 PF01101.13 EEA07301.1 - 0.024 15.2 6.8 0.047 14.3 4.7 1.4 1 0 0 1 1 1 0 HMG14 and HMG17 DUF164 PF02591.10 EEA07301.1 - 0.51 10.2 5.6 0.24 11.2 2.1 1.7 2 0 0 2 2 2 0 Putative zinc ribbon domain Rtf2 PF04641.7 EEA07301.1 - 0.65 9.1 11.9 1.8 7.6 6.7 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger HDA2-3 PF11496.3 EEA07301.1 - 1.3 7.7 9.0 2 7.1 6.2 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Sec23_trunk PF04811.10 EEA07304.1 - 7.3e-65 218.7 0.0 1e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EEA07304.1 - 7.6e-31 106.4 0.1 1.5e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEA07304.1 - 2.9e-14 52.3 4.4 5.7e-14 51.3 3.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEA07304.1 - 3.9e-12 45.6 0.0 1.3e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Gelsolin repeat Sec23_helical PF04815.10 EEA07304.1 - 1.2e-10 40.6 1.5 2.6e-05 23.5 0.1 2.5 1 1 1 2 2 2 2 Sec23/Sec24 helical domain VP_N-CPKC PF11475.3 EEA07304.1 - 0.04 13.4 0.7 0.09 12.3 0.5 1.5 1 0 0 1 1 1 0 Virion protein N terminal domain Pkinase PF00069.20 EEA07305.1 - 2.6e-38 131.6 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07305.1 - 2.3e-16 59.6 0.0 3.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA07305.1 - 3.1e-05 23.8 0.0 0.0009 19.0 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEA07305.1 - 0.013 14.3 0.3 0.02 13.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cse1 PF08506.5 EEA07307.1 - 1e-43 149.3 0.3 1.7e-42 145.2 0.2 2.3 1 1 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EEA07307.1 - 5.2e-43 146.9 5.4 5.2e-43 146.9 3.8 2.5 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EEA07307.1 - 1.1e-13 50.8 0.9 5.3e-13 48.6 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEA07307.1 - 9.8e-05 22.2 1.7 9.8e-05 22.2 1.1 3.1 3 0 0 3 3 3 1 Exportin 1-like protein Clathrin PF00637.15 EEA07311.1 - 0.0015 18.1 10.1 0.075 12.6 2.6 3.5 2 1 0 2 2 2 2 Region in Clathrin and VPS Ribosomal_S5 PF00333.15 EEA07312.1 - 1.7e-28 98.1 0.3 3.1e-28 97.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EEA07312.1 - 1.7e-20 72.0 0.0 3.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SEP PF08059.8 EEA07313.1 - 5e-19 68.3 0.0 8.3e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EEA07313.1 - 1.3e-09 37.9 0.1 4e-09 36.4 0.0 1.9 2 1 0 2 2 2 1 UBX domain GN3L_Grn1 PF08701.6 EEA07314.1 - 3e-16 59.0 21.9 5.1e-16 58.3 15.2 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EEA07314.1 - 4.5e-16 58.8 1.0 4.5e-14 52.4 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA07314.1 - 4.6e-05 22.7 6.5 5.3e-05 22.5 0.1 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 EEA07314.1 - 0.00012 21.2 0.1 0.00025 20.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEA07314.1 - 0.00023 20.6 0.0 0.38 10.1 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEA07314.1 - 0.042 14.6 3.3 0.12 13.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEA07314.1 - 0.045 13.7 0.2 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EEA07314.1 - 0.092 11.5 0.1 0.092 11.5 0.1 2.1 3 1 0 3 3 3 0 ArgK protein ABC_tran PF00005.22 EEA07314.1 - 0.12 12.6 1.4 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EEA07314.1 - 3.7 7.3 13.4 12 5.6 0.2 3.8 2 2 1 3 3 3 0 Dynamin family MFS_1 PF07690.11 EEA07315.1 - 2.5e-23 82.3 63.5 1.8e-18 66.3 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-B_box PF00643.19 EEA07316.1 - 7.8e-10 38.4 16.1 5.7e-05 22.9 2.6 2.5 2 0 0 2 2 2 2 B-box zinc finger GDI PF00996.13 EEA07317.1 - 3.8e-188 625.2 0.1 4.7e-188 624.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 EEA07317.1 - 9.9e-05 21.3 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Avidin PF01382.12 EEA07317.1 - 0.028 14.6 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Avidin family FAD_binding_3 PF01494.14 EEA07317.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CRAL_TRIO PF00650.15 EEA07318.1 - 1.2e-23 83.3 0.1 2.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 EEA07318.1 - 1.2e-06 28.8 5.7 0.015 15.5 0.2 3.2 3 0 0 3 3 3 2 Golgi-dynamics membrane-trafficking Coatomer_E PF04733.9 EEA07319.1 - 2.1e-17 63.2 6.6 2.8e-10 39.8 0.1 3.0 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.1 EEA07319.1 - 1e-08 35.3 0.0 0.0026 18.0 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07319.1 - 4.5e-08 32.4 0.5 0.011 15.5 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA07319.1 - 6e-08 32.2 0.0 5e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EEA07319.1 - 9.5e-08 31.8 0.1 0.00071 19.4 0.0 4.1 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA07319.1 - 2.3e-05 23.7 4.5 0.7 9.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR PF01535.15 EEA07319.1 - 5.7e-05 22.8 4.1 0.12 12.4 0.0 5.3 6 0 0 6 6 5 1 PPR repeat TPR_16 PF13432.1 EEA07319.1 - 0.00064 20.3 0.0 0.015 15.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07319.1 - 0.00067 20.0 0.0 0.77 10.5 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA07319.1 - 0.00086 19.3 3.9 0.075 13.1 0.2 3.6 2 1 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.1 EEA07319.1 - 0.0038 17.1 0.2 20 5.2 0.0 4.4 4 0 0 4 4 4 0 PPR repeat family TPR_15 PF13429.1 EEA07319.1 - 0.026 13.6 0.0 0.066 12.2 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA07319.1 - 0.033 14.1 0.0 50 4.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EEA07319.1 - 0.037 13.4 1.8 0.26 10.6 0.2 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Antirestrict PF03230.8 EEA07319.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Antirestriction protein TPR_7 PF13176.1 EEA07319.1 - 0.085 12.7 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 EEA07319.1 - 0.1 12.0 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) MSV199 PF10553.4 EEA07319.1 - 3 7.7 13.5 1.3 8.9 5.8 2.7 2 1 0 2 2 2 0 MSV199 domain DUF155 PF02582.9 EEA07320.1 - 7.6e-51 172.4 0.2 1.1e-50 171.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Peptidase_C14 PF00656.17 EEA07321.1 - 6.5e-36 124.2 0.1 2.5e-35 122.3 0.0 1.9 2 0 0 2 2 2 1 Caspase domain Abhydrolase_6 PF12697.2 EEA07322.1 - 4e-13 49.7 0.0 4.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA07322.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA07322.1 - 8.9e-09 35.2 0.0 3e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EEA07322.1 - 0.00036 19.1 0.0 0.00064 18.2 0.0 1.4 1 0 0 1 1 1 1 Ndr family Sel1 PF08238.7 EEA07323.1 - 1.3e-08 35.1 10.5 0.034 14.7 0.2 4.8 5 0 0 5 5 5 3 Sel1 repeat RunxI PF08504.6 EEA07323.1 - 0.023 15.1 0.1 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 Runx inhibition domain Ham1p_like PF01725.11 EEA07324.1 - 3.5e-47 160.2 0.0 4.3e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M14 PF00246.19 EEA07325.1 - 3.1e-18 66.3 0.1 1.4e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 Zinc carboxypeptidase Luciferase_N PF05295.6 EEA07325.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain TPR_11 PF13414.1 EEA07326.1 - 1.9e-08 33.8 0.3 5.6e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EEA07326.1 - 8.2e-08 32.4 0.1 0.002 18.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07326.1 - 1.9e-05 24.2 1.4 0.72 9.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07326.1 - 0.00015 22.0 0.0 0.33 11.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA07326.1 - 0.00035 20.0 3.6 0.3 10.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA07326.1 - 0.0036 17.9 0.0 3.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 EEA07326.1 - 0.041 13.9 0.0 0.15 12.1 0.0 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07326.1 - 0.086 12.7 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEA07326.1 - 0.086 13.0 0.6 3.6 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA07326.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA07326.1 - 0.14 11.9 1.3 16 5.5 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEA07326.1 - 0.18 11.6 1.1 10 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EEA07329.1 - 0.0013 18.5 2.2 0.77 9.7 0.2 4.0 3 1 0 3 3 3 3 WD domain, G-beta repeat Dus PF01207.12 EEA07330.1 - 5.6e-37 127.2 0.0 8e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) OB_NTP_bind PF07717.11 EEA07331.1 - 6.4e-19 67.8 0.1 2.2e-18 66.1 0.1 2.1 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA07331.1 - 4.5e-17 61.9 0.0 9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA07331.1 - 6.6e-15 54.7 0.0 1.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA07331.1 - 1.3e-11 44.2 1.1 3.3e-11 42.9 0.2 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA07331.1 - 1.6e-06 28.2 0.0 4.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEA07331.1 - 3.8e-05 23.5 2.9 0.12 12.2 0.7 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEA07331.1 - 0.0002 20.4 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EEA07331.1 - 0.00027 19.9 0.3 0.00062 18.7 0.2 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EEA07331.1 - 0.0053 16.0 0.3 0.1 11.7 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein ABC_tran PF00005.22 EEA07331.1 - 0.0066 16.7 2.1 0.023 14.9 0.1 2.7 3 1 1 4 4 4 1 ABC transporter Flavi_DEAD PF07652.9 EEA07331.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain KaiC PF06745.8 EEA07331.1 - 0.025 13.6 0.3 0.096 11.7 0.1 2.0 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 EEA07331.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EEA07331.1 - 0.036 13.5 0.1 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA07331.1 - 0.39 11.0 9.3 0.029 14.6 0.7 3.0 2 2 0 2 2 2 0 AAA domain Chordopox_G3 PF06129.7 EEA07333.1 - 0.015 15.4 1.0 0.015 15.4 0.7 2.0 2 1 0 2 2 2 0 Chordopoxvirus G3 protein DUF262 PF03235.9 EEA07333.1 - 0.24 11.3 5.6 0.3 11.0 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Spc97_Spc98 PF04130.8 EEA07334.1 - 2.6e-33 115.1 36.7 1.5e-23 82.9 13.7 3.4 3 1 0 3 3 3 2 Spc97 / Spc98 family Adaptin_N PF01602.15 EEA07335.1 - 6.2e-121 404.2 24.2 7.8e-121 403.9 16.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEA07335.1 - 1.7e-21 76.8 13.7 2.4e-19 69.8 1.4 4.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEA07335.1 - 3.2e-17 62.5 0.1 5.2e-09 36.2 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EEA07335.1 - 2.3e-12 45.8 2.1 0.00063 19.6 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat FliG_C PF01706.11 EEA07335.1 - 0.00021 21.2 0.4 0.0011 18.9 0.2 2.3 1 0 0 1 1 1 1 FliG C-terminal domain HEAT_EZ PF13513.1 EEA07335.1 - 0.00024 21.4 0.2 0.14 12.6 0.0 4.2 5 1 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA07335.1 - 1.6 9.2 5.6 1.5 9.2 0.0 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region PWWP PF00855.12 EEA07336.1 - 0.036 14.2 0.2 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 PWWP domain zf-RING_2 PF13639.1 EEA07337.1 - 1e-13 50.8 12.4 1.5e-13 50.2 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA07337.1 - 4.4e-10 39.0 8.1 6.4e-10 38.5 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07337.1 - 1.9e-09 37.4 13.2 3.1e-09 36.7 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA07337.1 - 2.1e-09 37.3 7.0 3.9e-09 36.5 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA07337.1 - 2.2e-08 33.6 10.3 3.5e-08 33.0 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA07337.1 - 1.2e-07 31.2 13.0 2.3e-07 30.3 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA07337.1 - 7.6e-05 22.3 4.7 7.6e-05 22.3 3.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EEA07337.1 - 0.013 15.2 3.8 0.029 14.1 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EEA07337.1 - 0.016 15.0 6.2 0.033 14.0 4.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EEA07337.1 - 0.26 11.2 13.5 1.2 9.0 9.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1244 PF06844.6 EEA07337.1 - 0.31 10.8 2.8 0.65 9.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-P11 PF03854.9 EEA07337.1 - 0.56 9.7 8.2 1.9 8.0 5.7 1.9 2 1 0 2 2 2 0 P-11 zinc finger TraG_N PF07916.6 EEA07337.1 - 5.5 5.3 7.7 7.4 4.8 5.3 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AAA PF00004.24 EEA07338.1 - 5.1e-13 49.3 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA07338.1 - 1.5e-10 41.2 0.0 3.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA07338.1 - 3.3e-05 23.9 0.0 0.0012 18.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA07338.1 - 0.00035 20.2 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EEA07338.1 - 0.00045 19.2 0.0 0.0014 17.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEA07338.1 - 0.00069 19.2 0.6 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA07338.1 - 0.0014 18.3 0.0 0.0049 16.6 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EEA07338.1 - 0.02 14.6 0.0 0.19 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EEA07338.1 - 0.055 12.9 0.0 2.6 7.4 0.0 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EEA07338.1 - 0.19 11.1 0.2 0.37 10.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA07338.1 - 0.24 11.7 2.6 3.3 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA07338.1 - 0.26 10.8 0.0 0.47 9.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 EEA07339.1 - 1 9.6 24.2 0.52 10.5 2.2 4.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1192 PF06698.6 EEA07339.1 - 3.9 7.3 8.9 10 6.0 2.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DAGK_acc PF00609.14 EEA07340.1 - 3.3e-30 105.3 0.3 6.3e-28 97.9 0.2 2.4 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EEA07340.1 - 3.4e-18 65.3 0.0 6.3e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-RING_2 PF13639.1 EEA07342.1 - 9.9e-10 38.0 8.8 2.3e-09 36.9 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA07342.1 - 6.2e-06 26.1 8.5 3.2e-05 23.8 5.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA07342.1 - 2.6e-05 23.8 2.8 2.6e-05 23.8 1.9 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEA07342.1 - 0.0005 19.7 9.0 0.0025 17.5 6.2 2.2 1 1 0 1 1 1 1 zinc-RING finger domain IncA PF04156.9 EEA07342.1 - 0.00071 19.2 5.5 0.00071 19.2 3.8 2.7 3 0 0 3 3 3 1 IncA protein zf-rbx1 PF12678.2 EEA07342.1 - 0.0013 18.7 13.3 0.012 15.7 8.3 2.9 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA07342.1 - 0.0024 17.4 10.5 0.029 14.0 7.2 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEA07342.1 - 0.01 15.5 1.6 0.01 15.5 1.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CENP-F_leu_zip PF10473.4 EEA07342.1 - 0.059 13.2 14.8 2.1 8.1 5.6 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.1 EEA07342.1 - 0.068 12.8 9.9 0.31 10.7 6.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA07342.1 - 0.13 12.1 6.6 0.073 12.9 2.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EEA07342.1 - 0.18 11.6 9.6 0.04 13.7 1.9 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EEA07342.1 - 2.9 8.0 8.1 10 6.2 5.6 2.1 1 1 0 1 1 1 0 RING-variant domain RsbU_N PF08673.5 EEA07344.1 - 0.0016 18.3 0.4 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoserine phosphatase RsbU, N-terminal domain Bromodomain PF00439.20 EEA07344.1 - 0.0027 17.5 0.9 0.0027 17.5 0.7 2.5 2 1 1 3 3 3 1 Bromodomain GST_C PF00043.20 EEA07344.1 - 0.04 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Elongin_A PF06881.6 EEA07345.1 - 0.01 16.1 2.1 0.052 13.9 1.4 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Imm14 PF15428.1 EEA07348.1 - 8.2 6.8 11.2 0.63 10.4 1.6 2.8 2 1 1 3 3 3 0 Immunity protein 14 PHD PF00628.24 EEA07349.1 - 4.3e-11 42.3 8.8 4.3e-11 42.3 6.1 2.8 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 EEA07349.1 - 1.5e-07 31.4 2.0 1.5e-07 31.4 1.4 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEA07349.1 - 1.8e-07 30.8 7.7 1.8e-07 30.8 5.3 3.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EEA07349.1 - 5.7e-06 25.9 3.9 5.7e-06 25.9 2.7 3.8 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA07349.1 - 1.6e-05 24.4 6.0 1.6e-05 24.4 4.2 3.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07349.1 - 0.0001 22.2 2.2 0.0001 22.2 1.5 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07349.1 - 0.0053 16.4 7.3 0.0053 16.4 5.1 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA07349.1 - 0.013 15.3 0.9 0.013 15.3 0.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EEA07349.1 - 0.019 14.7 0.5 0.019 14.7 0.3 3.3 4 0 0 4 4 4 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 EEA07349.1 - 0.059 12.8 5.1 0.39 10.2 1.0 3.1 2 0 0 2 2 2 0 P-11 zinc finger CAF-1_p150 PF11600.3 EEA07349.1 - 1.4 8.2 45.9 1.1 8.6 24.5 2.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L39 PF00832.15 EEA07350.1 - 2e-20 71.9 8.8 2.2e-20 71.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Sex_peptide PF08138.6 EEA07350.1 - 2.1 8.2 4.6 1.2 9.0 0.4 2.0 1 1 1 2 2 2 0 Sex peptide (SP) family eIF2A PF08662.6 EEA07351.1 - 3e-33 115.1 13.4 1.1e-26 93.7 2.4 4.8 4 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEA07351.1 - 0.00089 19.0 6.0 28 4.7 0.0 6.1 6 1 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.7 EEA07351.1 - 0.014 15.0 0.3 0.074 12.7 0.2 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.17 EEA07351.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07351.1 - 0.056 13.3 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEA07352.1 - 4.2e-34 115.1 23.5 4.7e-09 35.7 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EEA07352.1 - 0.00079 17.6 5.0 0.0026 15.9 2.3 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Orexin_rec2 PF03827.8 EEA07352.1 - 0.18 11.8 1.8 0.64 10.1 0.7 2.2 2 0 0 2 2 2 0 Orexin receptor type 2 DUF2750 PF11042.3 EEA07352.1 - 1.2 9.1 5.3 22 5.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2750) Arm PF00514.18 EEA07353.1 - 1.5e-14 53.1 0.1 0.0031 17.2 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEA07353.1 - 0.002 18.3 1.2 0.059 13.6 0.3 3.1 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 EEA07353.1 - 0.077 13.1 1.6 18 5.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 EEA07353.1 - 3 8.4 7.3 26 5.4 0.5 3.9 4 1 0 4 4 4 0 HEAT-like repeat CoaE PF01121.15 EEA07354.1 - 2.3e-42 144.4 0.0 2.7e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EEA07354.1 - 0.00057 20.6 0.4 0.00093 20.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain Cbl_N PF02262.11 EEA07354.1 - 0.079 12.6 1.8 0.085 12.5 0.4 1.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 AAA_28 PF13521.1 EEA07354.1 - 0.1 12.5 0.1 0.46 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain 7TM_GPCR_Srt PF10321.4 EEA07354.1 - 1.2 7.7 17.2 0.015 14.0 5.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt Mito_carr PF00153.22 EEA07358.1 - 2e-62 206.8 0.1 4.4e-19 67.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Utp11 PF03998.8 EEA07359.1 - 2.2e-49 168.4 16.3 4e-47 161.0 11.3 2.0 1 1 0 1 1 1 1 Utp11 protein HALZ PF02183.13 EEA07360.1 - 0.0012 18.4 27.9 0.02 14.5 4.5 6.2 4 1 1 5 5 5 3 Homeobox associated leucine zipper Filament PF00038.16 EEA07360.1 - 0.018 14.5 76.7 0.48 9.8 9.8 4.2 1 1 2 3 3 3 0 Intermediate filament protein IncA PF04156.9 EEA07360.1 - 0.021 14.4 94.3 0.049 13.2 11.1 4.6 1 1 2 4 4 4 0 IncA protein DUF4140 PF13600.1 EEA07360.1 - 0.022 15.1 0.0 0.022 15.1 0.0 6.4 2 1 2 7 7 7 0 N-terminal domain of unknown function (DUF4140) Mucin PF01456.12 EEA07364.1 - 0.49 10.1 23.3 3.9 7.2 0.2 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein ABC_tran PF00005.22 EEA07368.1 - 3e-53 179.7 3.2 5.9e-31 107.6 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EEA07368.1 - 4.7e-13 49.1 39.9 2e-09 37.2 9.3 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEA07368.1 - 4.6e-09 35.8 0.0 0.0044 16.2 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA07368.1 - 2e-07 31.8 0.0 0.021 15.6 0.0 3.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EEA07368.1 - 4.2e-06 26.9 4.8 0.00018 21.5 0.4 8.3 5 2 2 7 7 6 2 AAA domain AAA_22 PF13401.1 EEA07368.1 - 9.3e-06 25.8 0.1 0.3 11.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 EEA07368.1 - 2.7e-05 24.6 0.4 0.071 13.6 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 EEA07368.1 - 5.4e-05 23.2 1.8 0.0069 16.3 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EEA07368.1 - 5.8e-05 22.3 0.6 0.19 10.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEA07368.1 - 5.9e-05 23.3 0.9 0.64 10.3 0.0 3.6 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EEA07368.1 - 0.00019 21.3 0.5 0.54 10.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 EEA07368.1 - 0.00062 18.7 3.6 0.062 12.2 0.0 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein MobB PF03205.9 EEA07368.1 - 0.00078 19.1 0.4 0.43 10.2 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EEA07368.1 - 0.00083 18.8 0.3 0.83 9.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.17 EEA07368.1 - 0.0018 17.1 0.4 0.065 12.0 0.0 2.9 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.14 EEA07368.1 - 0.002 17.6 0.9 0.32 10.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EEA07368.1 - 0.0033 16.9 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain ArgK PF03308.11 EEA07368.1 - 0.0094 14.7 0.2 1.1 8.0 0.0 2.2 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EEA07368.1 - 0.014 15.5 0.0 2.1 8.5 0.0 3.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EEA07368.1 - 0.018 14.1 0.0 5.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EEA07368.1 - 0.019 15.1 4.3 0.069 13.3 0.2 3.7 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA07368.1 - 0.023 14.4 0.2 5.5 6.7 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EEA07368.1 - 0.024 14.1 1.1 5 6.5 0.0 4.3 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.22 EEA07368.1 - 0.031 13.7 1.1 1.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ATP-synt_ab PF00006.20 EEA07368.1 - 0.039 13.4 0.2 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EEA07368.1 - 0.043 13.6 0.1 0.043 13.6 0.0 3.5 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA_14 PF13173.1 EEA07368.1 - 0.072 12.9 0.0 0.072 12.9 0.0 5.0 5 1 1 6 6 6 0 AAA domain AAA_25 PF13481.1 EEA07368.1 - 0.076 12.3 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA07368.1 - 0.14 11.9 0.3 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 EEA07368.1 - 0.14 11.9 10.7 0.37 10.6 0.0 4.1 3 1 0 3 3 3 0 Dynamin family AAA_33 PF13671.1 EEA07368.1 - 0.16 11.8 0.1 8.4 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEA07368.1 - 0.19 11.3 4.6 0.7 9.5 0.0 3.0 4 0 0 4 4 2 0 NACHT domain AAA_30 PF13604.1 EEA07368.1 - 0.33 10.4 0.0 26 4.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EEA07369.1 - 0.085 12.0 0.1 0.085 12.0 0.1 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein HALZ PF02183.13 EEA07369.1 - 5.5 6.7 21.9 8.2 6.2 0.2 5.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper LAGLIDADG_1 PF00961.14 EEA07370.1 - 0.028 14.9 0.2 0.084 13.4 0.0 1.9 2 0 0 2 2 2 0 LAGLIDADG endonuclease NIF PF03031.13 EEA07370.1 - 0.059 13.0 0.1 0.087 12.4 0.1 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Glu_cyclase_2 PF05096.7 EEA07371.1 - 1.5e-38 132.3 0.0 4.4e-38 130.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine cyclotransferase SPRY PF00622.23 EEA07373.1 - 4.2e-09 36.5 0.2 4.4e-06 26.7 0.0 2.7 3 0 0 3 3 3 2 SPRY domain Rhodopsin_N PF10413.4 EEA07373.1 - 0.04 13.6 0.1 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin DHC_N1 PF08385.7 EEA07374.1 - 5.7e-137 457.5 16.5 5.7e-137 457.5 11.4 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EEA07374.1 - 8.6e-112 374.4 3.4 6.2e-96 322.0 2.9 3.0 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EEA07374.1 - 1.1e-100 337.0 16.1 1.4e-88 297.1 4.1 6.0 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EEA07374.1 - 2.6e-81 272.5 0.0 6.1e-81 271.3 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 EEA07374.1 - 2.1e-34 118.8 9.4 4.5e-34 117.7 6.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EEA07374.1 - 4.5e-32 110.7 0.3 6.1e-27 93.9 0.1 3.1 3 0 0 3 3 2 2 ATP-binding dynein motor region D5 AAA_5 PF07728.9 EEA07374.1 - 5e-28 97.5 0.0 2.8e-10 40.0 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 EEA07374.1 - 1.6e-24 86.3 0.5 9.7e-24 83.7 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 EEA07374.1 - 1.2e-20 73.7 0.0 3.5e-19 68.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 EEA07374.1 - 6.8e-19 68.3 0.0 4.3e-05 23.7 0.0 6.6 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA07374.1 - 1.4e-11 44.6 0.1 0.03 14.4 0.0 6.6 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 EEA07374.1 - 1.6e-08 34.7 0.0 0.042 13.8 0.0 5.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 EEA07374.1 - 3.6e-08 33.0 0.0 0.14 11.9 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_17 PF13207.1 EEA07374.1 - 8.8e-08 33.0 0.4 1.2 9.9 0.0 5.9 5 0 0 5 5 4 1 AAA domain Zeta_toxin PF06414.7 EEA07374.1 - 2.8e-07 29.8 0.0 0.079 12.0 0.0 4.5 4 0 0 4 4 4 2 Zeta toxin Mg_chelatase PF01078.16 EEA07374.1 - 6.3e-06 25.4 3.1 0.1 11.7 0.0 4.0 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEA07374.1 - 1.6e-05 24.8 0.8 1.7 8.5 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.1 EEA07374.1 - 2.1e-05 24.8 1.5 22 5.3 0.0 6.7 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.17 EEA07374.1 - 0.00013 22.0 0.3 25 5.0 0.0 5.7 5 0 0 5 5 4 0 RNA helicase RuvB_N PF05496.7 EEA07374.1 - 0.00028 20.0 0.1 0.075 12.0 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEA07374.1 - 0.00029 20.3 1.4 4.5 6.6 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 EEA07374.1 - 0.0027 17.1 0.0 1.5 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EEA07374.1 - 0.0088 16.0 0.4 14 5.5 0.0 4.9 7 0 0 7 7 4 0 AAA domain Asn_synthase PF00733.16 EEA07374.1 - 0.0094 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase FtsK_SpoIIIE PF01580.13 EEA07374.1 - 0.012 15.0 0.0 2.2 7.6 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EEA07374.1 - 0.056 13.0 3.0 35 3.9 0.0 4.4 5 0 0 5 5 4 0 AAA domain DSPc PF00782.15 EEA07375.1 - 1.2e-20 73.4 0.8 1.3e-16 60.4 0.2 3.3 2 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA07375.1 - 0.00069 19.0 0.2 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CTF_NFI PF00859.13 EEA07375.1 - 0.073 12.8 1.0 0.13 11.9 0.7 1.3 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Scm3 PF10384.4 EEA07375.1 - 0.095 12.1 1.9 0.89 9.0 0.1 2.6 2 0 0 2 2 2 0 Centromere protein Scm3 Apc3 PF12895.2 EEA07376.1 - 0.0023 18.0 12.0 0.0071 16.4 2.8 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEA07376.1 - 0.0054 16.6 1.8 0.051 13.5 0.0 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat SPC25 PF06703.6 EEA07377.1 - 2e-07 30.7 0.3 3.3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) NKAIN PF05640.9 EEA07377.1 - 0.058 12.3 4.9 0.074 12.0 3.2 1.4 1 1 0 1 1 1 0 Na,K-Atpase Interacting protein Thioredoxin PF00085.15 EEA07379.1 - 3.5e-34 116.6 0.0 2.3e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA07379.1 - 4.4e-12 46.1 3.3 1.3e-09 38.0 0.2 3.1 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEA07379.1 - 2e-08 34.3 0.1 0.0031 17.6 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EEA07379.1 - 1.2e-06 28.2 0.0 0.0096 15.6 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.1 EEA07379.1 - 1.7e-06 28.0 0.7 0.15 12.1 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EEA07379.1 - 7.3e-06 25.5 0.0 0.061 12.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EEA07379.1 - 0.001 18.6 0.0 0.48 9.9 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EEA07379.1 - 0.0012 18.8 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.19 EEA07379.1 - 0.068 13.1 0.2 12 5.9 0.2 2.9 2 1 0 2 2 2 0 Glutaredoxin Pkinase PF00069.20 EEA07380.1 - 2.4e-47 161.2 0.1 4.7e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07380.1 - 7.5e-23 80.9 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA07380.1 - 0.19 11.4 0.3 0.52 10.0 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family zf-DHHC PF01529.15 EEA07381.1 - 4.8e-30 104.2 10.0 4.8e-30 104.2 6.9 2.5 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EEA07381.1 - 2.8e-24 85.2 0.0 9e-14 51.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA07381.1 - 3.5e-19 68.7 1.9 1.9e-08 34.5 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EEA07381.1 - 7.4e-17 60.2 0.2 8.6e-07 28.4 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EEA07381.1 - 1.2e-15 56.0 0.6 2.4e-05 24.1 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEA07381.1 - 7.8e-13 48.2 0.1 1.3e-06 28.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA_11 PF13086.1 EEA07382.1 - 2.3e-75 253.1 0.0 1.3e-74 250.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEA07382.1 - 2.4e-59 200.0 0.1 9.7e-59 198.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA07382.1 - 1.9e-12 46.7 0.0 5.3e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EEA07382.1 - 9e-07 28.6 0.0 0.0037 16.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EEA07382.1 - 1.6e-05 24.5 0.2 0.036 13.5 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EEA07382.1 - 0.00014 22.2 1.4 0.00014 22.2 1.0 3.8 2 2 1 3 3 1 1 AAA domain T2SE PF00437.15 EEA07382.1 - 0.002 17.0 0.0 0.0085 15.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 EEA07382.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA07382.1 - 0.015 15.4 0.1 0.089 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEA07382.1 - 0.017 14.1 0.7 0.12 11.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EEA07382.1 - 0.019 15.2 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EEA07382.1 - 0.025 14.3 0.1 0.39 10.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EEA07382.1 - 0.026 14.0 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Antimicrobial10 PF08105.6 EEA07382.1 - 0.033 13.7 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Metchnikowin family AAA_25 PF13481.1 EEA07382.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EEA07382.1 - 1.1 8.5 12.0 0.36 10.0 0.1 3.9 3 1 1 4 4 4 0 UvrD/REP helicase N-terminal domain Mnd1 PF03962.10 EEA07383.1 - 5.3e-44 150.1 12.1 5.9e-44 149.9 8.4 1.0 1 0 0 1 1 1 1 Mnd1 family Penicillinase_R PF03965.11 EEA07383.1 - 0.0015 18.5 0.8 0.0029 17.6 0.5 1.5 1 0 0 1 1 1 1 Penicillinase repressor DUF848 PF05852.6 EEA07383.1 - 0.0031 17.3 6.5 0.0031 17.3 4.5 1.9 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) TBPIP PF07106.8 EEA07383.1 - 0.0038 16.8 15.4 0.15 11.6 6.1 2.1 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Peptidase_C6 PF00851.13 EEA07383.1 - 0.019 13.6 3.8 0.024 13.2 2.6 1.2 1 0 0 1 1 1 0 Helper component proteinase TrmB PF01978.14 EEA07383.1 - 0.031 13.9 0.0 0.086 12.5 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CHASE3 PF05227.8 EEA07383.1 - 0.045 13.4 4.5 0.046 13.4 1.2 2.2 1 1 1 2 2 2 0 CHASE3 domain GLE1 PF07817.8 EEA07383.1 - 0.06 12.2 6.7 0.081 11.8 4.7 1.2 1 0 0 1 1 1 0 GLE1-like protein Erp_C PF06780.6 EEA07383.1 - 0.081 12.7 8.6 0.13 12.0 5.9 1.4 1 1 0 1 1 1 0 Erp protein C-terminus SDH_alpha PF03313.10 EEA07383.1 - 0.13 11.2 1.9 0.19 10.7 1.3 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain XPC-binding PF09280.6 EEA07383.1 - 0.13 11.6 2.6 0.42 10.1 1.6 2.0 1 1 0 1 1 1 0 XPC-binding domain ApoO PF09769.4 EEA07383.1 - 0.25 11.0 1.8 0.58 9.8 0.7 2.0 2 1 0 2 2 2 0 Apolipoprotein O HAUS-augmin3 PF14932.1 EEA07383.1 - 0.25 10.4 11.1 0.55 9.3 7.7 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF745 PF05335.8 EEA07383.1 - 0.29 10.6 3.3 0.46 9.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PTPA PF03095.10 EEA07383.1 - 0.54 9.3 3.3 0.78 8.8 2.3 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Spc7 PF08317.6 EEA07383.1 - 0.55 8.8 18.3 0.91 8.1 10.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.8 EEA07383.1 - 0.71 9.2 7.9 0.27 10.6 3.8 1.7 2 0 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.7 EEA07383.1 - 0.88 9.3 9.9 2.7 7.7 5.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EEA07383.1 - 1.1 8.1 9.8 1.3 7.9 6.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 EEA07383.1 - 1.1 8.4 7.9 1.3 8.2 5.1 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF883 PF05957.8 EEA07383.1 - 1.3 9.4 3.4 3.5 8.0 2.1 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 EEA07383.1 - 3.7 6.5 7.3 5.2 6.0 5.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EEA07383.1 - 3.7 7.1 15.1 0.32 10.5 7.0 1.7 2 0 0 2 2 2 0 IncA protein Uds1 PF15456.1 EEA07383.1 - 4.4 7.3 11.2 2.8 7.9 5.7 2.1 2 1 0 2 2 2 0 Up-regulated During Septation V_ATPase_I PF01496.14 EEA07383.1 - 5.1 4.8 12.0 26 2.5 7.5 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 EEA07383.1 - 7.5 6.3 15.9 2 8.2 7.6 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF342 PF03961.8 EEA07383.1 - 8.2 4.7 14.7 6.1 5.1 9.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 EEA07383.1 - 9.3 6.4 15.3 58 3.9 10.6 2.1 1 1 0 1 1 1 0 Syntaxin Occludin_ELL PF07303.8 EEA07383.1 - 9.4 7.0 11.1 1.4 9.7 4.6 2.0 2 1 0 2 2 1 0 Occludin homology domain DSS1_SEM1 PF05160.8 EEA07384.1 - 7.3e-06 25.6 26.9 0.00028 20.5 18.5 2.2 1 1 0 1 1 1 1 DSS1/SEM1 family PG_binding_2 PF08823.6 EEA07384.1 - 0.66 10.1 3.4 1.5 8.9 1.0 2.0 1 1 1 2 2 2 0 Putative peptidoglycan binding domain Ribosomal_S19e PF01090.14 EEA07385.1 - 2.1e-49 166.5 0.0 2.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ubiquitin PF00240.18 EEA07386.1 - 0.0001 21.5 0.3 0.066 12.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.1 EEA07386.1 - 0.0017 18.5 0.1 0.0055 16.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Pro_isomerase PF00160.16 EEA07387.1 - 7.2e-40 136.7 0.6 8.4e-40 136.5 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EEA07388.1 - 9.8e-42 142.3 0.4 5.4e-41 139.8 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA07388.1 - 5.7e-28 96.6 0.7 7.6e-27 92.9 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EEA07388.1 - 0.00039 19.5 0.0 0.00083 18.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEA07388.1 - 0.001 17.5 0.1 0.14 10.5 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EEA07388.1 - 0.0017 18.0 0.1 0.0064 16.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EEA07388.1 - 0.0042 16.9 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EEA07388.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA07388.1 - 0.016 15.3 0.7 0.94 9.6 0.2 2.9 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EEA07389.1 - 1.4e-30 106.3 0.0 5.3e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07389.1 - 2.1e-15 56.5 0.0 2.1e-12 46.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase PQQ PF01011.16 EEA07389.1 - 0.00068 19.0 1.0 1.7 8.2 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 EEA07389.1 - 0.034 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NifZ PF04319.8 EEA07389.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 NifZ domain zf-AN1 PF01428.11 EEA07390.1 - 3.2e-12 46.1 8.3 3.2e-12 46.1 5.8 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EEA07390.1 - 5.3e-11 41.8 9.2 5.3e-11 41.8 6.4 2.2 2 0 0 2 2 2 1 A20-like zinc finger DUF4428 PF14471.1 EEA07390.1 - 0.098 12.4 9.2 0.56 9.9 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-RING_4 PF14570.1 EEA07390.1 - 1.5 8.4 10.7 6 6.5 3.5 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.11 EEA07390.1 - 1.9 8.3 11.2 1.4 8.7 1.6 2.5 2 1 0 2 2 2 0 FYVE-type zinc finger Actin PF00022.14 EEA07391.1 - 4.9e-91 305.0 0.0 5.8e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA07391.1 - 0.0062 15.1 0.0 1.8 7.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein LRR_4 PF12799.2 EEA07392.1 - 9.2e-13 47.5 25.3 1.2e-05 24.8 0.4 4.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA07392.1 - 4.3e-11 42.3 7.9 6.8e-06 25.7 0.3 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 EEA07392.1 - 1.7e-09 37.4 1.1 3.4e-09 36.5 0.8 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EEA07392.1 - 0.0055 16.6 8.6 15 6.3 0.2 5.5 4 1 1 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 EEA07392.1 - 0.057 13.4 8.2 35 4.9 0.1 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 EEA07392.1 - 0.79 9.9 5.9 26 5.2 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Hid1 PF12722.2 EEA07392.1 - 8.1 3.9 9.2 9.6 3.7 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_5 PF14634.1 EEA07395.1 - 5.2 6.8 21.1 0.045 13.4 8.2 2.5 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA07395.1 - 5.5 7.1 17.4 6.2 6.9 5.5 3.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FtsH_ext PF06480.10 EEA07396.1 - 0.22 11.6 5.0 0.5 10.5 3.5 1.6 1 0 0 1 1 1 0 FtsH Extracellular zf-RING_5 PF14634.1 EEA07396.1 - 0.39 10.4 15.9 0.9 9.3 11.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 EEA07396.1 - 0.92 9.0 13.3 2.4 7.7 9.2 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 EEA07396.1 - 3.6 7.6 16.1 10 6.2 11.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07396.1 - 5.1 6.8 15.8 15 5.3 11.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07396.1 - 5.7 6.8 16.0 16 5.4 11.1 1.8 1 1 0 1 1 1 0 Ring finger domain ABC_tran PF00005.22 EEA07397.1 - 2.6e-35 121.7 0.0 6.8e-18 65.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EEA07397.1 - 9.5e-14 50.7 1.7 2.2e-13 49.5 1.2 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EEA07397.1 - 4.4e-10 40.0 13.2 0.00036 20.6 0.1 4.9 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 EEA07397.1 - 7.1e-10 38.4 6.3 9.7e-05 21.6 1.3 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EEA07397.1 - 8.7e-09 34.6 3.5 8.7e-09 34.6 2.4 2.5 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.1 EEA07397.1 - 9.1e-08 31.5 4.6 0.0066 15.5 0.6 3.4 3 1 0 3 3 3 3 AAA ATPase domain AAA_29 PF13555.1 EEA07397.1 - 1.5e-06 27.5 0.0 0.038 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.2 EEA07397.1 - 2.3e-06 27.8 5.5 3.4e-05 24.1 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EEA07397.1 - 2.9e-06 26.8 2.8 2.9e-06 26.8 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 EEA07397.1 - 5e-05 23.5 0.3 0.5 10.5 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEA07397.1 - 9.5e-05 21.2 0.0 0.3 9.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Miro PF08477.8 EEA07397.1 - 0.0001 22.7 0.3 0.0078 16.6 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 EEA07397.1 - 0.00011 21.4 2.5 0.088 11.9 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEA07397.1 - 0.00014 22.1 0.4 0.19 12.0 0.1 2.9 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA07397.1 - 0.00016 21.3 0.2 0.076 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EEA07397.1 - 0.00031 20.8 0.5 0.48 10.6 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Fer4_9 PF13187.1 EEA07397.1 - 0.00044 20.4 2.0 0.00044 20.4 1.4 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_17 PF13207.1 EEA07397.1 - 0.00064 20.5 1.6 1.2 10.0 0.0 3.0 2 2 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EEA07397.1 - 0.00081 19.1 13.1 0.0016 18.2 9.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEA07397.1 - 0.00085 19.1 2.8 0.00085 19.1 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain VirE PF05272.6 EEA07397.1 - 0.001 18.5 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E SRP54 PF00448.17 EEA07397.1 - 0.0015 18.0 0.6 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EEA07397.1 - 0.0022 17.7 0.0 0.28 10.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 EEA07397.1 - 0.0023 17.6 1.8 0.0023 17.6 1.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EEA07397.1 - 0.0025 18.5 3.6 0.0028 18.3 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain PduV-EutP PF10662.4 EEA07397.1 - 0.0029 17.1 0.1 0.058 12.8 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EEA07397.1 - 0.0036 17.4 0.0 0.58 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA07397.1 - 0.0043 16.9 1.2 0.35 10.7 0.2 3.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA07397.1 - 0.005 16.5 0.1 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 EEA07397.1 - 0.0053 17.1 5.1 0.068 13.4 1.0 2.6 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EEA07397.1 - 0.0071 16.2 0.0 8 6.4 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_3 PF12798.2 EEA07397.1 - 0.0075 16.7 4.8 0.0075 16.7 3.3 2.6 2 1 0 2 2 1 1 4Fe-4S binding domain AAA_25 PF13481.1 EEA07397.1 - 0.0088 15.4 0.0 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA07397.1 - 0.01 15.7 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA07397.1 - 0.016 14.1 0.3 4.4 6.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain UPF0079 PF02367.12 EEA07397.1 - 0.016 14.8 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EEA07397.1 - 0.022 14.7 0.0 6.9 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EEA07397.1 - 0.024 14.5 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EEA07397.1 - 0.058 13.1 0.5 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EEA07397.1 - 0.06 12.0 1.0 0.3 9.7 0.0 2.4 3 0 0 3 3 2 0 G-protein alpha subunit FeoB_N PF02421.13 EEA07397.1 - 0.092 12.0 0.5 7.6 5.8 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B Zeta_toxin PF06414.7 EEA07397.1 - 0.12 11.4 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 EEA07397.1 - 0.13 11.0 0.2 1.4 7.6 0.1 2.1 2 0 0 2 2 2 0 ArgK protein MMR_HSR1 PF01926.18 EEA07397.1 - 0.24 11.3 1.0 11 5.9 0.1 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.1 EEA07397.1 - 0.32 11.0 9.8 0.04 13.9 0.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 EEA07397.1 - 0.64 9.7 4.2 21 4.7 0.0 3.9 6 0 0 6 6 3 0 NTPase Fer4_4 PF12800.2 EEA07397.1 - 1.1 9.8 13.0 0.079 13.3 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.1 EEA07397.1 - 1.2 7.4 3.7 0.43 8.9 0.1 1.9 2 1 0 3 3 3 0 AAA domain Fer4_17 PF13534.1 EEA07397.1 - 4.7 7.6 11.1 67 3.9 7.9 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEA07397.1 - 4.9 7.6 12.1 71 3.9 8.4 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain PNTB PF02233.11 EEA07398.1 - 2.6e-159 530.9 20.1 2.6e-159 530.9 13.9 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EEA07398.1 - 3.6e-44 150.3 0.1 4.6e-42 143.4 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 EEA07398.1 - 1e-28 99.2 4.6 1e-28 99.2 3.2 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3814) AlaDh_PNT_N PF05222.10 EEA07398.1 - 1.4e-19 70.4 0.0 2.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.14 EEA07398.1 - 9.9e-07 28.0 0.4 0.00045 19.4 0.1 3.2 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EEA07398.1 - 0.00025 20.9 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EEA07398.1 - 0.025 14.1 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EEA07398.1 - 0.08 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding PID PF00640.18 EEA07399.1 - 0.0038 17.1 0.8 0.16 11.9 0.2 2.2 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Tcp10_C PF07202.8 EEA07399.1 - 0.01 15.3 0.9 0.072 12.6 0.1 2.2 2 0 0 2 2 2 0 T-complex protein 10 C-terminus MerB PF03243.10 EEA07399.1 - 0.014 15.1 0.3 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Alkylmercury lyase GH97_N PF14508.1 EEA07399.1 - 0.016 14.2 1.7 0.021 13.8 1.2 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Filament PF00038.16 EEA07399.1 - 0.032 13.6 16.4 1.2e+02 2.0 1.3 2.0 1 1 0 1 1 1 0 Intermediate filament protein SDH_alpha PF03313.10 EEA07399.1 - 0.097 11.6 3.5 0.15 11.1 0.2 2.0 2 0 0 2 2 2 0 Serine dehydratase alpha chain DUF3373 PF11853.3 EEA07399.1 - 0.27 9.7 8.8 0.079 11.4 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) PXA PF02194.10 EEA07399.1 - 0.33 10.4 7.8 0.052 13.1 2.1 1.9 2 0 0 2 2 2 0 PXA domain DUF745 PF05335.8 EEA07399.1 - 0.51 9.8 7.9 0.27 10.7 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Prefoldin PF02996.12 EEA07399.1 - 0.92 9.1 15.4 2.9 7.5 1.9 3.6 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EEA07399.1 - 7.3 6.4 14.1 0.74 9.6 0.5 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EEA07399.1 - 7.6 6.4 18.4 0.25 11.2 2.6 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) SlyX PF04102.7 EEA07399.1 - 9.6 6.6 7.6 19 5.7 0.6 2.8 3 0 0 3 3 3 0 SlyX RNase_H2-Ydr279 PF09468.5 EEA07401.1 - 7.3e-13 48.3 10.9 9.8e-13 47.9 7.6 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3306 PF11748.3 EEA07402.1 - 0.065 13.8 0.0 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) U3_snoRNA_assoc PF08297.6 EEA07402.1 - 0.65 10.2 5.3 0.15 12.2 0.4 2.5 3 0 0 3 3 3 0 U3 snoRNA associated TB2_DP1_HVA22 PF03134.14 EEA07403.1 - 4e-18 64.9 9.5 5.4e-18 64.5 6.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RRM_1 PF00076.17 EEA07406.1 - 3.1e-17 61.9 0.0 4.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07406.1 - 5.6e-12 45.4 0.1 1.5e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07406.1 - 2.6e-05 23.9 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_5 PF12695.2 EEA07407.1 - 1.2e-16 60.7 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA07407.1 - 3.2e-09 37.0 0.0 6.4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA07407.1 - 0.00033 20.4 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EEA07407.1 - 0.00039 19.7 0.5 0.018 14.2 0.3 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEA07407.1 - 0.0024 17.3 1.1 0.41 10.0 0.1 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EEA07407.1 - 0.0026 17.2 0.3 0.024 14.0 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) HupF_HypC PF01455.13 EEA07407.1 - 0.0032 17.4 0.0 0.7 9.9 0.0 2.6 2 0 0 2 2 2 1 HupF/HypC family DUF4393 PF14337.1 EEA07407.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4393) UPF0227 PF05728.7 EEA07407.1 - 0.0066 16.1 0.2 0.025 14.3 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EEA07407.1 - 0.012 15.1 0.1 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EEA07407.1 - 0.14 11.3 0.1 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF915 PF06028.6 EEA07407.1 - 0.15 11.1 0.5 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) VPS9 PF02204.13 EEA07408.1 - 0.0075 16.2 0.3 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Transket_pyr PF02779.19 EEA07409.1 - 3.7e-47 160.1 0.0 6.2e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EEA07409.1 - 4.4e-37 127.4 0.0 8.3e-37 126.5 0.0 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component Peptidase_S15 PF02129.13 EEA07410.1 - 2.7e-58 197.5 0.1 3.9e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EEA07410.1 - 4.9e-16 59.2 0.0 1.1e-15 58.0 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EEA07410.1 - 0.00032 20.6 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA07410.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA07410.1 - 0.0041 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EEA07410.1 - 0.091 12.6 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase PSS PF03034.10 EEA07411.1 - 2.2e-85 286.5 17.8 1.1e-84 284.1 12.3 2.1 1 1 0 1 1 1 1 Phosphatidyl serine synthase ENTH PF01417.15 EEA07412.1 - 1.5e-11 44.2 0.4 4.9e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 ENTH domain SF-assemblin PF06705.6 EEA07413.1 - 4.3e-10 39.1 16.4 1.5e-08 34.0 1.9 2.6 1 1 1 2 2 2 1 SF-assemblin/beta giardin NSP2_assoc PF14758.1 EEA07413.1 - 0.0055 16.8 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 Non-essential region of nsp2 of arterivirus polyprotein DUF3480 PF11979.3 EEA07413.1 - 0.0067 15.0 0.7 0.011 14.3 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DUF1664 PF07889.7 EEA07413.1 - 0.007 16.1 14.6 0.036 13.8 0.7 3.9 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EEA07413.1 - 0.034 14.5 2.2 0.034 14.5 1.5 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SbcD_C PF12320.3 EEA07413.1 - 0.18 11.8 1.8 0.64 10.0 0.0 2.6 3 1 0 3 3 2 0 Type 5 capsule protein repressor C-terminal domain IFT57 PF10498.4 EEA07413.1 - 0.23 10.1 11.3 0.26 9.9 6.0 2.3 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 YgaB PF14182.1 EEA07413.1 - 0.26 11.5 14.5 0.59 10.4 0.5 3.7 1 1 2 3 3 3 0 YgaB-like protein DUF869 PF05911.6 EEA07413.1 - 0.31 9.2 10.7 0.39 8.9 7.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) APG17 PF04108.7 EEA07413.1 - 0.4 9.4 13.5 0.13 11.0 3.1 2.9 2 1 1 3 3 3 0 Autophagy protein Apg17 DUF445 PF04286.7 EEA07413.1 - 0.93 8.9 12.9 14 5.0 9.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Spectrin PF00435.16 EEA07413.1 - 1.2 9.4 6.4 0.54 10.5 0.1 2.7 3 1 0 3 3 3 0 Spectrin repeat DASH_Dam1 PF08653.5 EEA07413.1 - 1.4 8.7 4.4 1.7 8.4 0.5 3.0 3 1 1 4 4 4 0 DASH complex subunit Dam1 Cauli_DNA-bind PF03310.8 EEA07413.1 - 1.8 8.4 12.3 0.14 12.0 2.3 2.7 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein V-SNARE PF05008.10 EEA07413.1 - 1.9 8.6 11.3 2.1 8.5 0.3 3.9 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Allexi_40kDa PF05549.6 EEA07413.1 - 3.7 6.7 9.6 6.5 5.9 1.5 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein HsbA PF12296.3 EEA07413.1 - 3.8 7.3 8.6 0.76 9.6 0.7 3.2 2 2 1 3 3 3 0 Hydrophobic surface binding protein A ACBP PF00887.14 EEA07414.1 - 2.9e-18 65.3 0.1 5.4e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.1 EEA07414.1 - 8.2e-18 64.0 0.0 4.7e-09 36.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA07414.1 - 1.9e-17 63.3 0.0 1.2e-16 60.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA07414.1 - 1.6e-16 60.3 0.1 2.3e-13 50.2 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA07414.1 - 3.3e-16 58.1 0.1 2e-08 33.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EEA07414.1 - 4.9e-11 41.7 0.5 9.6e-05 22.2 0.0 4.5 5 1 1 6 6 6 2 Ankyrin repeat DUF3686 PF12458.3 EEA07414.1 - 0.088 11.0 0.1 0.93 7.6 0.0 2.0 1 1 0 2 2 2 0 ATPase involved in DNA repair Peptidase_C12 PF01088.16 EEA07417.1 - 6.4e-52 175.8 0.0 9.6e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SNF2_N PF00176.18 EEA07418.1 - 1.5e-57 194.6 0.0 2.1e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA07418.1 - 1.7e-11 43.8 0.0 4.3e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA07418.1 - 7.5e-07 29.1 0.1 3.2e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA07418.1 - 4.4e-05 23.0 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EEA07418.1 - 0.00052 18.9 0.0 0.0075 15.1 0.0 2.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 EEA07418.1 - 0.048 12.6 0.0 0.13 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) EnY2 PF10163.4 EEA07420.1 - 0.054 13.4 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 Pkinase PF00069.20 EEA07421.1 - 2.4e-55 187.5 3.7 1.1e-36 126.2 0.3 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07421.1 - 9.8e-25 87.0 0.2 4.8e-18 65.1 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA07421.1 - 8.4e-05 21.6 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEA07421.1 - 0.0001 21.2 0.1 0.0001 21.2 0.0 2.3 3 0 0 3 3 3 1 Seadornavirus VP7 APH PF01636.18 EEA07421.1 - 0.0023 17.6 0.4 0.0091 15.7 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA07421.1 - 0.026 13.8 2.4 0.028 13.7 0.7 1.7 2 0 0 2 2 2 0 RIO1 family CRAL_TRIO PF00650.15 EEA07423.1 - 1.4e-30 105.8 0.0 2.2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA07423.1 - 9.2e-07 28.8 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA07423.1 - 1 9.5 3.2 0.97 9.6 0.1 2.6 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain DUF1694 PF07997.6 EEA07425.1 - 0.022 14.6 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Peptidase_C97 PF05903.9 EEA07426.1 - 6e-41 139.7 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 EEA07426.1 - 9.9e-18 63.6 7.0 1.3e-17 63.2 0.2 2.9 3 0 0 3 3 3 1 PUB domain UBA PF00627.26 EEA07426.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF778 PF05608.7 EEA07426.1 - 0.17 11.8 1.7 0.51 10.2 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF778) Baculo_PEP_C PF04513.7 EEA07426.1 - 0.78 9.5 5.8 1.3 8.8 2.6 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KH_1 PF00013.24 EEA07427.1 - 5e-27 93.3 0.0 1.1e-07 31.3 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EEA07427.1 - 1.5e-16 59.5 3.8 0.00019 21.0 0.1 5.4 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 EEA07427.1 - 1.9e-07 30.5 0.1 0.4 10.2 0.0 4.2 4 0 0 4 4 4 2 KH domain KH_4 PF13083.1 EEA07427.1 - 1.4e-06 27.7 0.0 0.045 13.3 0.0 4.3 4 0 0 4 4 4 1 KH domain Hormone_2 PF00123.15 EEA07427.1 - 0.009 15.8 0.3 0.32 10.8 0.0 2.6 2 0 0 2 2 2 1 Peptide hormone Cas_Csm6 PF09659.5 EEA07428.1 - 0.001 17.8 0.1 0.0021 16.7 0.0 1.4 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) DUF533 PF04391.7 EEA07428.1 - 0.05 12.9 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Glyco_transf_41 PF13844.1 EEA07429.1 - 5.6e-42 143.2 0.8 8.2e-24 83.4 0.2 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EEA07429.1 - 1.2e-29 101.7 9.1 3.1e-12 45.9 0.3 4.5 2 1 3 5 5 5 4 TPR repeat TPR_2 PF07719.12 EEA07429.1 - 2.8e-22 76.7 0.4 1.6e-05 24.4 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA07429.1 - 3.2e-22 77.1 4.5 2e-05 24.0 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEA07429.1 - 3.5e-18 63.9 7.7 0.00034 20.1 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07429.1 - 6.2e-18 64.5 0.3 1.1e-08 34.8 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA07429.1 - 1.3e-16 59.3 11.2 0.0035 17.4 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEA07429.1 - 8e-13 47.1 1.0 0.066 13.0 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07429.1 - 1.1e-07 31.7 0.0 0.15 12.7 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA07429.1 - 1.9e-07 30.7 3.7 0.015 15.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA07429.1 - 9.4e-05 22.9 0.0 1.5 9.5 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEA07429.1 - 0.00013 22.2 0.0 1.3 9.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA07429.1 - 0.00015 22.0 0.0 0.025 14.8 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA07429.1 - 0.00021 21.0 0.0 0.0026 17.5 0.0 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEA07429.1 - 0.026 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat CSTF2_hinge PF14327.1 EEA07430.1 - 1.1e-21 76.6 1.6 2e-21 75.8 0.3 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EEA07430.1 - 8.5e-19 66.9 0.0 1.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07430.1 - 7.4e-12 45.0 0.0 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07430.1 - 2.1e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Snf7 PF03357.16 EEA07431.1 - 0.041 13.2 16.1 0.069 12.5 11.1 1.4 1 1 0 1 1 1 0 Snf7 DUF775 PF05603.7 EEA07431.1 - 0.091 12.2 3.4 0.12 11.9 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Ist1 PF03398.9 EEA07431.1 - 0.19 11.1 7.0 0.047 13.1 2.5 1.5 2 0 0 2 2 2 0 Regulator of Vps4 activity in the MVB pathway Syntaxin PF00804.20 EEA07431.1 - 0.71 10.0 14.0 0.14 12.3 1.7 2.7 2 1 0 2 2 2 0 Syntaxin Flagellin_N PF00669.15 EEA07431.1 - 1 9.1 8.3 0.73 9.6 4.1 1.9 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region UPF0147 PF03685.8 EEA07431.1 - 1.2 9.0 5.3 2.8 7.8 0.2 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) SNF2_N PF00176.18 EEA07433.1 - 1.4e-56 191.5 2.0 1.4e-56 191.5 1.4 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA07433.1 - 8.4e-13 47.9 0.0 2.9e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA07433.1 - 3e-11 43.4 0.0 3e-11 43.4 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA07433.1 - 3.6e-08 33.0 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.22 EEA07435.1 - 8.1e-32 110.3 0.0 2.7e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EEA07435.1 - 3.2e-20 72.7 16.2 4.4e-20 72.2 11.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EEA07435.1 - 4e-06 27.0 7.5 0.0001 22.3 0.3 3.7 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEA07435.1 - 0.00028 21.6 0.3 0.0015 19.3 0.1 2.4 1 1 1 2 2 1 1 AAA domain AAA_14 PF13173.1 EEA07435.1 - 0.00039 20.3 0.0 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEA07435.1 - 0.0008 18.6 0.7 0.081 12.1 0.0 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA07435.1 - 0.0025 17.8 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEA07435.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EEA07435.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EEA07435.1 - 0.018 15.3 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA07435.1 - 0.023 14.4 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PRK PF00485.13 EEA07435.1 - 0.025 14.1 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2439 PF10382.4 EEA07436.1 - 2.8e-12 46.6 1.1 2.8e-12 46.6 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) EF-hand_1 PF00036.27 EEA07437.1 - 1.4e-25 86.5 6.6 1.5e-06 27.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA07437.1 - 1e-23 83.2 3.5 3.5e-12 46.2 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA07437.1 - 2.4e-20 70.5 3.0 0.00012 21.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA07437.1 - 7.3e-20 69.3 1.4 4.3e-05 22.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EEA07437.1 - 4.9e-11 42.0 8.1 7.5e-05 22.2 0.2 4.4 2 2 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEA07437.1 - 3.3e-09 36.7 0.1 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EEA07437.1 - 0.0016 18.3 0.0 0.81 9.6 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain RST PF12174.3 EEA07437.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.2 EEA07437.1 - 0.014 15.1 4.1 1.5 8.6 0.0 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EEA07437.1 - 0.15 11.6 0.4 5.6 6.4 0.0 2.6 2 1 1 3 3 3 0 Caleosin related protein zf-DHHC PF01529.15 EEA07438.1 - 3.9e-42 143.6 8.3 3.9e-42 143.6 5.8 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PH PF00169.24 EEA07442.1 - 7e-05 22.9 1.9 9.8e-05 22.5 0.5 1.8 2 0 0 2 2 2 1 PH domain Cut8_N PF14482.1 EEA07442.1 - 0.012 15.5 1.3 0.028 14.4 0.9 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain PH_10 PF15411.1 EEA07442.1 - 0.17 12.0 2.8 0.2 11.8 0.2 2.0 1 1 2 3 3 3 0 Pleckstrin homology domain Mre11_DNA_bind PF04152.9 EEA07443.1 - 2.2e-35 122.0 2.6 5.3e-35 120.8 0.0 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EEA07443.1 - 5.1e-24 84.7 0.3 1e-23 83.8 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA07443.1 - 4e-07 29.9 0.0 3.6e-06 26.8 0.0 2.4 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Pneumo_phosprot PF02478.11 EEA07445.1 - 0.062 12.8 2.6 1.2 8.5 0.1 2.8 2 0 0 2 2 2 0 Pneumovirus phosphoprotein Pkinase PF00069.20 EEA07449.1 - 1.5e-62 211.0 0.1 2.4e-62 210.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07449.1 - 5e-43 147.0 0.0 8.9e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M43 PF05572.8 EEA07449.1 - 0.085 12.4 1.3 0.66 9.5 0.1 2.4 1 1 1 2 2 2 0 Pregnancy-associated plasma protein-A Phos_pyr_kin PF08543.7 EEA07450.1 - 0.00032 19.9 0.0 0.002 17.3 0.0 2.1 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEA07450.1 - 0.057 12.5 0.6 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Laminin_G_3 PF13385.1 EEA07453.1 - 6.6e-13 49.1 3.5 1.9e-06 28.1 0.0 3.7 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily GCC2_GCC3 PF07699.8 EEA07453.1 - 0.00074 19.0 6.4 0.00074 19.0 4.4 4.5 3 1 1 4 4 4 2 GCC2 and GCC3 PCI PF01399.22 EEA07454.1 - 1.7e-09 37.9 1.1 1.7e-09 37.9 0.8 2.6 2 0 0 2 2 2 1 PCI domain WD40 PF00400.27 EEA07455.1 - 3e-13 49.0 8.4 6.1e-07 29.0 1.7 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2009 PF09418.5 EEA07456.1 - 3.6e-185 616.1 4.8 4.8e-120 401.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2009) E2F_TDP PF02319.15 EEA07457.1 - 1.4e-12 46.9 0.3 2.7e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EEA07457.1 - 0.041 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4367 PF14285.1 EEA07458.1 - 0.89 8.8 9.7 0.05 12.9 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) zf-CCCH PF00642.19 EEA07459.1 - 1e-08 34.6 3.4 1.3e-08 34.3 1.4 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EEA07459.1 - 0.00035 20.3 10.2 0.0009 19.0 7.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA07459.1 - 0.051 13.3 15.7 0.043 13.5 9.7 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-UDP PF14569.1 EEA07459.1 - 0.14 11.9 2.3 0.34 10.6 1.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 EEA07459.1 - 0.18 11.3 11.0 0.038 13.5 3.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EEA07459.1 - 0.3 11.1 17.7 0.026 14.5 8.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07459.1 - 0.37 10.4 19.5 0.026 14.1 9.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EEA07459.1 - 0.41 10.5 8.1 0.76 9.6 5.6 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.1 EEA07459.1 - 6.3 6.4 12.5 13 5.4 8.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SHS2_Rpb7-N PF03876.12 EEA07462.1 - 1.4e-05 25.1 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SET_assoc PF11767.3 EEA07463.1 - 0.0018 17.5 1.3 0.076 12.3 0.0 2.7 2 1 1 3 3 3 2 Histone lysine methyltransferase SET associated DUF3294 PF07957.6 EEA07463.1 - 0.024 14.1 5.5 1.4 8.4 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3294) Nefa_Nip30_N PF10187.4 EEA07463.1 - 3.1 8.0 8.4 0.18 11.9 1.0 2.4 2 1 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 LAMTOR PF15454.1 EEA07463.1 - 5.1 7.4 10.8 18 5.7 0.1 3.0 2 1 1 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PLU-1 PF08429.6 EEA07464.1 - 2e-36 125.5 47.8 2.2e-27 95.8 8.7 9.2 8 1 0 8 8 8 7 PLU-1-like protein PHD PF00628.24 EEA07464.1 - 1.1e-06 28.2 2.4 3.1e-06 26.7 0.4 2.4 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 EEA07464.1 - 0.0068 16.1 0.2 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Lum_binding PF00677.12 EEA07465.1 - 0.074 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Lumazine binding domain Ribosomal_L36e PF01158.13 EEA07466.1 - 8.3e-38 128.3 5.1 9.5e-38 128.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.6 EEA07467.1 - 5.8e-103 343.9 5.3 8.5e-103 343.4 3.6 1.1 1 0 0 1 1 1 1 Bystin Peptidase_M16 PF00675.15 EEA07468.1 - 2.7e-36 124.5 0.0 1.2e-35 122.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA07468.1 - 1.8e-17 63.6 0.6 3.7e-09 36.5 0.1 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF927 PF06048.6 EEA07468.1 - 0.023 13.9 0.5 0.86 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF927) PHD PF00628.24 EEA07469.1 - 8.4e-07 28.5 10.8 8.4e-07 28.5 7.5 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EEA07469.1 - 0.00035 20.2 5.8 0.00035 20.2 4.0 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 Dynamin_N PF00350.18 EEA07469.1 - 0.001 18.9 0.7 0.0037 17.0 0.5 2.0 1 0 0 1 1 1 1 Dynamin family DUF3449 PF11931.3 EEA07469.1 - 0.0021 17.5 6.7 0.0021 17.5 4.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) PHD_2 PF13831.1 EEA07469.1 - 0.0052 16.0 6.2 0.0052 16.0 4.3 3.0 3 0 0 3 3 3 1 PHD-finger DUF3133 PF11331.3 EEA07469.1 - 0.042 13.4 0.8 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) PWWP PF00855.12 EEA07469.1 - 0.12 12.6 0.1 0.12 12.6 0.0 2.8 2 0 0 2 2 2 0 PWWP domain Zip PF02535.17 EEA07469.1 - 2.3 7.1 4.2 4.7 6.1 2.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 EEA07469.1 - 6.9 6.3 11.5 2.8 7.5 5.2 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region C1_3 PF07649.7 EEA07469.1 - 8.7 6.4 8.3 2.8 8.0 3.3 2.0 2 0 0 2 2 2 0 C1-like domain GATA PF00320.22 EEA07470.1 - 1.5e-06 27.4 5.9 1.5e-06 27.4 4.1 3.8 4 0 0 4 4 4 2 GATA zinc finger His_Phos_1 PF00300.17 EEA07471.1 - 9.7e-17 61.5 0.0 2.2e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SpoU_methylase PF00588.14 EEA07472.1 - 1.6e-23 83.1 0.0 3.1e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family Hydrolase_3 PF08282.7 EEA07473.1 - 4.9e-18 65.6 7.2 1.3e-15 57.7 5.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEA07473.1 - 1.5e-05 24.4 0.0 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EEA07473.1 - 0.0041 17.3 0.1 0.065 13.3 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA07473.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DDRGK PF09756.4 EEA07474.1 - 5.9e-40 136.6 22.2 7.5e-40 136.3 15.4 1.1 1 0 0 1 1 1 1 DDRGK domain DUF1803 PF08820.5 EEA07474.1 - 0.055 13.1 3.0 0.065 12.9 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1803) Peptidase_C15 PF01470.12 EEA07474.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyroglutamyl peptidase RAMPs PF03787.10 EEA07474.1 - 0.21 11.3 2.8 0.34 10.7 1.9 1.4 1 0 0 1 1 1 0 RAMP superfamily ETRAMP PF09716.5 EEA07474.1 - 3.1 7.7 8.9 0.73 9.8 2.9 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF809 PF05663.6 EEA07474.1 - 6.8 6.6 9.6 45 3.9 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF809) TRAP-gamma PF07074.7 EEA07474.1 - 9.4 5.7 12.4 25 4.3 8.5 1.8 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Anophelin PF10731.4 EEA07475.1 - 0.15 12.2 0.2 0.15 12.2 0.1 2.2 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito CDC50 PF03381.10 EEA07476.1 - 5.2e-29 101.2 9.1 3.9e-28 98.4 6.2 2.1 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DbpA PF03880.10 EEA07476.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Rab5ip PF07019.7 EEA07477.1 - 2.1e-10 40.5 7.0 2.7e-10 40.2 4.8 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF1673 PF07895.6 EEA07477.1 - 0.17 11.3 1.4 0.18 11.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3317 PF11779.3 EEA07477.1 - 3.8 7.0 9.2 1.8 8.0 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) DUF2244 PF10003.4 EEA07477.1 - 4.4 6.6 5.1 2.1 7.6 2.0 1.6 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) HTH_IclR PF09339.5 EEA07478.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-RING_2 PF13639.1 EEA07479.1 - 7.4e-11 41.7 12.8 2e-10 40.2 8.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EEA07479.1 - 1e-08 35.1 7.2 2.7e-08 33.8 5.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEA07479.1 - 9.1e-07 28.4 10.0 2e-06 27.3 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07479.1 - 2e-06 27.4 11.0 5.2e-06 26.0 7.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA07479.1 - 7.4e-05 22.6 12.5 7.4e-05 22.6 8.7 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07479.1 - 0.00098 18.7 13.9 0.003 17.1 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA07479.1 - 0.011 15.5 4.3 0.011 15.5 3.0 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_3 PF07649.7 EEA07479.1 - 0.19 11.8 3.9 0.82 9.7 2.7 2.2 1 0 0 1 1 1 0 C1-like domain FANCL_C PF11793.3 EEA07479.1 - 0.22 11.4 9.2 0.67 9.9 6.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEA07479.1 - 0.29 10.9 7.3 1.1 8.9 5.1 2.1 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EEA07479.1 - 0.44 10.2 10.9 0.96 9.1 7.5 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EEA07479.1 - 1.4 9.0 12.0 3.2 7.8 8.3 1.6 1 0 0 1 1 1 0 RING-variant domain WD40 PF00400.27 EEA07480.1 - 2.9e-41 137.8 5.3 6.9e-09 35.2 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA07480.1 - 0.0021 17.8 1.6 0.15 11.7 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A SieB PF14163.1 EEA07483.1 - 0.025 14.1 0.1 0.025 14.1 0.1 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B HemY_N PF07219.8 EEA07483.1 - 0.83 9.2 3.1 3.5 7.2 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus TB2_DP1_HVA22 PF03134.14 EEA07484.1 - 1.1e-35 121.2 5.4 1.9e-35 120.5 3.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3816 PF12822.2 EEA07484.1 - 0.015 15.2 2.4 0.021 14.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) CAF1A PF12253.3 EEA07485.1 - 3.6e-10 39.8 5.0 1e-09 38.3 3.5 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A G-patch PF01585.18 EEA07486.1 - 1.2e-15 57.0 2.4 1.6e-15 56.6 1.7 1.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEA07486.1 - 0.0009 19.0 0.5 0.002 17.9 0.4 1.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site IF-2B PF01008.12 EEA07487.1 - 2.2e-16 59.7 4.1 1.3e-14 53.8 2.8 2.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Rep_fac_C PF08542.6 EEA07487.1 - 0.015 15.2 0.3 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 Replication factor C C-terminal domain DUF912 PF06024.7 EEA07488.1 - 0.13 12.3 0.2 0.13 12.3 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0302 PF08864.5 EEA07489.1 - 0.03 14.1 0.9 0.033 13.9 0.1 1.6 2 0 0 2 2 2 0 UPF0302 domain DUF3505 PF12013.3 EEA07489.1 - 0.036 14.3 0.3 0.036 14.3 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) Longin PF13774.1 EEA07490.1 - 4.7e-25 86.9 0.2 8e-25 86.2 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEA07490.1 - 1.3e-15 56.7 0.4 2.2e-15 56.0 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin UPRTase PF14681.1 EEA07491.1 - 5.8e-61 205.3 0.0 6.9e-61 205.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEA07491.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WbqC PF08889.6 EEA07491.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 WbqC-like protein family SelP_N PF04592.9 EEA07491.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nudix_N_2 PF14803.1 EEA07491.1 - 0.13 11.9 0.4 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 Nudix N-terminal DnaJ PF00226.26 EEA07492.1 - 4e-08 32.8 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HECT PF00632.20 EEA07493.1 - 3.8e-62 210.2 1.6 1.9e-61 207.9 1.1 2.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 EEA07493.1 - 1.9e-05 24.7 0.2 9e-05 22.5 0.1 2.2 1 0 0 1 1 1 1 SPRY domain UBA PF00627.26 EEA07493.1 - 0.0067 16.2 0.1 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Inositol_P PF00459.20 EEA07494.1 - 1.4e-40 139.3 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family zf-C3HC4_2 PF13923.1 EEA07495.1 - 2.9e-08 33.5 13.1 4.7e-08 32.9 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07495.1 - 3.5e-08 32.9 11.5 5.8e-08 32.2 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07495.1 - 3.9e-08 32.8 10.2 6.2e-08 32.2 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA07495.1 - 1.2e-07 31.2 7.8 2e-07 30.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07495.1 - 1.6e-07 31.0 12.6 2.5e-07 30.4 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEA07495.1 - 2.9e-05 23.6 7.8 0.0011 18.6 2.0 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA07495.1 - 0.00085 19.1 12.3 0.0017 18.1 8.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EEA07495.1 - 0.026 14.2 5.9 0.043 13.5 4.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 EEA07495.1 - 0.048 13.7 6.3 0.077 13.1 4.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger Rtf2 PF04641.7 EEA07495.1 - 0.062 12.5 0.2 0.089 11.9 0.2 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger U-box PF04564.10 EEA07495.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 EEA07495.1 - 1 8.9 9.3 1.7 8.2 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ost4 PF10215.4 EEA07495.1 - 8.2 6.0 8.5 2.9 7.4 1.8 2.2 2 0 0 2 2 2 0 Oligosaccaryltransferase Pkinase PF00069.20 EEA07496.1 - 6.7e-60 202.4 0.0 3e-39 134.7 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07496.1 - 9.6e-28 96.9 0.0 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEA07496.1 - 4.1e-09 36.5 0.1 1.8e-05 24.6 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA07496.1 - 0.00072 18.6 0.4 0.0025 16.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEA07496.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EEA07496.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEA07496.1 - 0.023 14.2 0.3 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 EEA07496.1 - 0.057 12.7 0.2 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family TPR_11 PF13414.1 EEA07498.1 - 2e-50 168.2 12.5 1.5e-19 69.3 0.4 4.2 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEA07498.1 - 3.4e-41 137.1 21.4 3.8e-08 32.5 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07498.1 - 4.8e-38 126.0 16.5 3.3e-07 29.7 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07498.1 - 1.8e-24 85.4 9.9 1.2e-13 50.7 0.1 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA07498.1 - 1.3e-18 65.2 20.7 0.00022 20.7 0.1 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEA07498.1 - 5.8e-18 65.0 0.1 8.6e-07 29.4 0.0 4.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEA07498.1 - 2.6e-16 59.7 1.9 0.00023 21.4 0.1 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA07498.1 - 1.2e-15 56.3 11.5 0.00077 19.4 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEA07498.1 - 1.7e-14 52.9 0.0 0.28 11.9 0.0 6.7 4 3 4 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA07498.1 - 1e-09 38.1 0.0 0.074 12.9 0.0 4.6 2 1 3 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EEA07498.1 - 1.8e-09 37.5 14.2 2.1e-06 27.7 2.8 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEA07498.1 - 2.5e-08 33.1 7.6 0.027 14.2 0.0 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA07498.1 - 2.2e-06 27.7 11.6 0.63 10.6 0.1 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEA07498.1 - 6.5e-06 25.8 0.8 0.62 10.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EEA07498.1 - 8.4e-05 21.5 10.2 0.049 12.3 0.0 3.6 1 1 4 5 5 5 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 EEA07498.1 - 0.0003 20.6 16.6 0.78 9.6 0.1 6.3 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EEA07498.1 - 0.0019 18.1 5.5 0.54 10.1 1.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.6 EEA07498.1 - 0.0066 15.8 1.5 0.018 14.4 1.1 1.8 1 0 0 1 1 1 1 XPC-binding domain SNAP PF14938.1 EEA07498.1 - 0.0071 15.5 11.3 0.47 9.5 3.9 3.1 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.9 EEA07498.1 - 0.012 14.7 5.3 0.72 8.9 1.1 3.7 2 2 1 3 3 3 0 Coatomer epsilon subunit PPR PF01535.15 EEA07498.1 - 0.015 15.2 1.7 0.078 12.9 0.1 2.9 2 0 0 2 2 2 0 PPR repeat KapB PF08810.5 EEA07498.1 - 0.023 14.7 3.0 0.1 12.6 0.6 2.6 2 0 0 2 2 2 0 Kinase associated protein B SHNi-TPR PF10516.4 EEA07498.1 - 0.073 12.3 2.9 0.9 8.8 0.1 3.7 5 0 0 5 5 5 0 SHNi-TPR MIT PF04212.13 EEA07498.1 - 0.58 10.0 8.2 8.2 6.3 0.0 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 EEA07498.1 - 2 7.7 12.8 0.32 10.3 0.6 3.6 2 1 2 4 4 4 0 26S proteasome subunit RPN7 RabGAP-TBC PF00566.13 EEA07499.1 - 4e-12 46.0 4.4 4e-12 46.0 3.0 4.7 3 2 1 5 5 5 2 Rab-GTPase-TBC domain WD40 PF00400.27 EEA07500.1 - 9.9e-59 193.2 32.5 6.1e-11 41.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA07500.1 - 0.00071 17.8 4.5 0.22 9.6 0.1 3.6 2 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EEA07500.1 - 0.0028 17.8 1.1 1.2 9.4 0.0 3.8 3 1 0 3 3 3 1 PQQ-like domain VID27 PF08553.5 EEA07500.1 - 0.091 10.9 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pkinase PF00069.20 EEA07501.1 - 3.5e-34 118.1 0.0 4.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07501.1 - 1.8e-16 59.9 0.0 2.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA07501.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA07501.1 - 0.0073 16.0 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family ATG16 PF08614.6 EEA07502.1 - 0.19 11.5 30.8 0.46 10.2 21.2 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Myb_DNA-bind_3 PF12776.2 EEA07502.1 - 1.2 9.8 6.9 0.86 10.2 1.5 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain IncA PF04156.9 EEA07502.1 - 1.7 8.1 33.2 14 5.2 23.0 2.1 1 1 0 1 1 1 0 IncA protein ASL_C PF08328.6 EEA07502.1 - 2.9 7.7 13.6 0.17 11.7 3.3 2.6 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DUF3450 PF11932.3 EEA07502.1 - 6.1 6.0 20.7 0.085 12.1 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Epimerase PF01370.16 EEA07503.1 - 8.5e-43 146.4 0.0 1.1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA07503.1 - 3.1e-10 39.2 0.0 6.5e-10 38.1 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA07503.1 - 1.6e-09 37.0 0.0 0.00014 20.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEA07503.1 - 1.5e-08 33.8 0.0 2.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEA07503.1 - 8.5e-08 31.4 0.0 3.6e-06 26.1 0.0 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA07503.1 - 0.0036 17.3 0.0 0.0057 16.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA07503.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 EEA07503.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 EEA07503.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 KR domain MORN PF02493.15 EEA07504.1 - 1.5e-47 156.5 72.4 9.6e-08 31.3 0.2 10.3 10 0 0 10 10 10 10 MORN repeat CENP-C_C PF11699.3 EEA07506.1 - 0.00066 19.6 0.8 0.0011 18.8 0.5 1.5 1 1 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EEA07506.1 - 0.0016 17.8 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain chaperone_DMP PF10448.4 EEA07506.1 - 0.059 13.2 0.4 0.082 12.7 0.3 1.2 1 0 0 1 1 1 0 20S proteasome chaperone Ras PF00071.17 EEA07507.1 - 4e-58 195.3 0.2 5.3e-58 194.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07507.1 - 2.3e-19 70.0 0.0 4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA07507.1 - 8e-14 51.2 0.3 1.1e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA07507.1 - 1.1e-06 28.2 0.0 3.4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA07507.1 - 5.3e-05 23.1 0.1 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA07507.1 - 6.5e-05 22.1 0.1 9.3e-05 21.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA07507.1 - 0.00029 20.1 0.2 0.00066 18.9 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EEA07507.1 - 0.016 14.5 0.1 0.27 10.5 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EEA07507.1 - 0.05 13.3 0.2 0.069 12.8 0.1 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EEA07507.1 - 0.062 13.4 0.0 5 7.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain zf-MIZ PF02891.15 EEA07508.1 - 2.3e-17 62.2 3.7 4.5e-17 61.2 0.8 2.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger PHD PF00628.24 EEA07508.1 - 0.0035 17.0 15.5 0.0038 16.8 2.2 3.7 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.1 EEA07508.1 - 0.019 15.0 4.1 0.022 14.8 1.4 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EEA07508.1 - 0.35 10.6 3.1 1 9.1 2.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EEA07508.1 - 0.78 9.5 7.5 0.1 12.3 1.9 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 EEA07509.1 - 5.4e-68 228.9 0.3 2.3e-67 226.9 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07509.1 - 1.1e-30 106.6 0.3 3.9e-28 98.2 0.2 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07509.1 - 1e-06 27.9 0.7 8.6e-05 21.6 0.0 3.3 3 1 1 4 4 4 1 Kinase-like Kdo PF06293.9 EEA07509.1 - 0.018 14.1 0.1 0.037 13.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3751 PF12571.3 EEA07510.1 - 0.17 11.6 3.9 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Phage tail-collar fibre protein V-SNARE_C PF12352.3 EEA07512.1 - 0.0081 16.2 0.2 0.022 14.8 0.1 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.9 EEA07512.1 - 0.011 15.0 1.7 0.011 15.0 1.2 1.9 2 0 0 2 2 2 0 Laminin Domain I DUF2121 PF09894.4 EEA07512.1 - 0.11 11.7 4.6 0.19 11.0 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Flavi_capsid PF01003.14 EEA07512.1 - 0.12 11.9 0.2 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavivirus capsid protein C Snapin_Pallidin PF14712.1 EEA07512.1 - 3.1 8.1 9.7 2.7 8.3 0.8 2.5 2 0 0 2 2 2 0 Snapin/Pallidin COPI_assoc PF08507.5 EEA07513.1 - 5.2e-06 26.1 0.8 7.1e-06 25.7 0.5 1.2 1 0 0 1 1 1 1 COPI associated protein UbiA PF01040.13 EEA07513.1 - 0.02 14.1 5.0 0.027 13.7 3.5 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Claudin_2 PF13903.1 EEA07513.1 - 0.04 13.5 4.6 0.41 10.3 0.4 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction GHMP_kinases_N PF00288.21 EEA07513.1 - 0.054 13.5 1.8 0.1 12.6 0.2 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF4231 PF14015.1 EEA07513.1 - 0.086 12.8 5.2 0.97 9.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) EF-hand_8 PF13833.1 EEA07513.1 - 0.088 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair Phageshock_PspG PF09583.5 EEA07513.1 - 1.9 8.6 7.0 3.5 7.7 0.8 2.4 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) COPI_assoc PF08507.5 EEA07514.1 - 2.3e-07 30.5 4.7 3.8e-07 29.8 3.3 1.3 1 0 0 1 1 1 1 COPI associated protein EF-hand_8 PF13833.1 EEA07514.1 - 1.6e-06 27.5 0.2 3.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair PrgI PF12666.2 EEA07514.1 - 0.002 18.2 7.8 0.013 15.6 0.4 2.6 2 1 0 2 2 2 1 PrgI family protein EF-hand_1 PF00036.27 EEA07514.1 - 0.0057 15.8 0.1 0.012 14.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEA07514.1 - 0.012 15.3 0.2 0.032 14.0 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain DUF4383 PF14325.1 EEA07514.1 - 0.013 15.4 3.2 0.013 15.4 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Cg6151-P PF10233.4 EEA07514.1 - 0.074 13.0 3.6 0.22 11.5 2.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF4231 PF14015.1 EEA07514.1 - 0.2 11.6 6.9 0.44 10.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3228 PF11539.3 EEA07515.1 - 2.8e-75 251.7 0.0 3.2e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) DUF4404 PF14357.1 EEA07516.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF384 PF04064.8 EEA07517.1 - 6e-15 54.5 0.7 2.7e-14 52.4 0.5 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF383 PF04063.9 EEA07517.1 - 1.6e-07 31.0 1.7 9.6e-06 25.2 0.5 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF383) Proteasome PF00227.21 EEA07518.1 - 3.4e-54 183.0 0.0 4.2e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA07518.1 - 7.1e-13 47.6 0.0 1.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Tfb2 PF03849.9 EEA07519.1 - 3.9e-36 124.4 11.4 1.1e-17 63.7 0.1 3.4 3 0 0 3 3 3 3 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEA07519.1 - 0.12 12.0 0.0 0.39 10.4 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain GTP_EFTU PF00009.22 EEA07520.1 - 1.7e-45 154.8 0.0 2.5e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA07520.1 - 2.5e-18 66.0 0.1 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA07520.1 - 9.5e-06 25.6 0.0 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA07520.1 - 0.00064 19.6 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arm PF00514.18 EEA07521.1 - 0.00044 19.9 1.0 1.7 8.5 0.1 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EEA07521.1 - 0.46 10.7 3.2 6.3 7.1 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat RNB PF00773.14 EEA07522.1 - 3.6e-95 318.9 3.1 6.3e-95 318.1 2.1 1.4 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EEA07522.1 - 0.094 12.2 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Nab2 PF11517.3 EEA07524.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HMG_box PF00505.14 EEA07525.1 - 1.6e-22 79.5 4.9 1.6e-22 79.5 3.4 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA07525.1 - 3.5e-17 62.5 7.1 5.1e-17 61.9 4.9 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEA07525.1 - 7.7e-05 22.4 4.9 7.7e-05 22.4 3.4 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.7 EEA07525.1 - 0.00075 19.1 0.2 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain Imm35 PF15581.1 EEA07525.1 - 0.033 14.1 3.4 0.047 13.6 0.2 2.0 1 1 1 2 2 2 0 Immunity protein 35 DUF1014 PF06244.7 EEA07525.1 - 0.13 12.4 6.2 0.035 14.3 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) PFK PF00365.15 EEA07526.1 - 4e-33 114.5 0.4 1.4e-22 80.0 0.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase Peptidase_M3 PF01432.15 EEA07527.1 - 2e-49 168.9 0.0 5.4e-49 167.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M3 MCM_N PF14551.1 EEA07527.1 - 0.074 13.5 0.8 22 5.5 0.0 3.5 3 1 0 3 3 3 0 MCM N-terminal domain HMG_box PF00505.14 EEA07529.1 - 0.089 13.0 0.4 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA07529.1 - 0.82 10.0 4.0 0.41 11.0 0.6 2.0 2 0 0 2 2 2 0 HMG-box domain DUF1620 PF07774.8 EEA07530.1 - 1.6e-20 73.3 8.4 1.6e-20 73.3 5.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EEA07530.1 - 0.014 14.8 0.0 0.34 10.3 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain NGP1NT PF08153.7 EEA07531.1 - 1.7e-35 121.8 0.4 4.9e-35 120.3 0.3 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EEA07531.1 - 2.8e-19 69.1 0.4 6.1e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA07531.1 - 1.4e-05 24.4 0.0 0.00029 20.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEA07531.1 - 2e-05 23.8 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EEA07531.1 - 0.018 14.3 0.2 0.99 8.6 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3388 PF11868.3 EEA07531.1 - 0.053 12.6 0.7 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) Dynamin_N PF00350.18 EEA07531.1 - 2 8.2 7.5 0.91 9.3 0.1 3.5 3 2 0 3 3 3 0 Dynamin family DUF2365 PF10157.4 EEA07532.1 - 0.0019 18.0 1.1 0.0023 17.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) TerD PF02342.13 EEA07532.1 - 0.0083 15.4 0.4 0.0091 15.3 0.3 1.0 1 0 0 1 1 1 1 TerD domain zf-DHHC PF01529.15 EEA07533.1 - 9.1e-40 135.8 19.4 9.1e-40 135.8 13.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L37e PF01907.14 EEA07534.1 - 7.8e-24 83.2 15.2 1.4e-23 82.3 10.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.13 EEA07534.1 - 0.0022 17.7 0.2 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 SelR domain RPN7 PF10602.4 EEA07535.1 - 1.9e-44 151.1 1.0 3.4e-44 150.3 0.7 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEA07535.1 - 1.7e-16 60.4 0.4 7.5e-16 58.3 0.1 2.2 2 0 0 2 2 2 1 PCI domain DUF2854 PF11016.3 EEA07536.1 - 0.16 11.5 0.9 0.69 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) PA26 PF04636.8 EEA07537.1 - 1.7e-39 135.8 0.4 1.9e-24 86.2 0.0 2.1 1 1 1 2 2 2 2 PA26 p53-induced protein (sestrin) Rer1 PF03248.8 EEA07539.1 - 8e-65 217.7 11.5 1e-64 217.3 8.0 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 EEA07539.1 - 0.85 8.8 5.6 1.7 7.8 3.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DnaJ PF00226.26 EEA07540.1 - 8e-17 60.7 1.5 3.1e-16 58.8 1.0 2.1 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.26 EEA07540.1 - 4e-10 39.5 5.4 1.7e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA07540.1 - 0.0053 16.8 11.0 0.45 10.6 0.1 4.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain OmpH PF03938.9 EEA07540.1 - 0.068 13.0 16.3 0.035 14.0 9.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UPF0449 PF15136.1 EEA07540.1 - 0.13 12.5 7.7 0.54 10.4 5.4 2.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Zip PF02535.17 EEA07540.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DXP_reductoisom PF02670.11 EEA07540.1 - 0.4 11.2 2.4 1 9.8 1.7 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PP2C PF00481.16 EEA07542.1 - 7.1e-17 61.6 0.3 7.1e-17 61.6 0.2 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA07542.1 - 1.9e-08 33.9 0.0 4.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA07542.1 - 0.00049 19.8 0.0 0.0042 16.8 0.0 2.0 1 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Tektin PF03148.9 EEA07542.1 - 0.004 15.7 0.9 0.0065 15.0 0.6 1.2 1 0 0 1 1 1 1 Tektin family DUF972 PF06156.8 EEA07542.1 - 0.029 14.7 0.4 0.092 13.1 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EEA07542.1 - 0.14 11.7 3.4 0.27 10.7 2.3 1.4 1 0 0 1 1 1 0 IncA protein Oleosin PF01277.12 EEA07542.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Oleosin Cyclin PF08613.6 EEA07543.1 - 5.3e-30 104.7 0.9 9.1e-30 104.0 0.7 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA07543.1 - 7.3e-08 32.0 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain T4_Gp59_N PF08993.5 EEA07543.1 - 0.042 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase AA_kinase PF00696.23 EEA07544.1 - 1.1e-38 133.1 2.0 5.9e-38 130.7 0.5 2.1 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 EEA07544.1 - 3.8e-11 42.5 0.4 8.8e-11 41.3 0.1 1.8 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 EEA07545.1 - 1.9e-35 122.2 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07545.1 - 2.3e-26 92.4 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA07545.1 - 0.00056 19.7 0.1 0.00087 19.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2 PF00168.25 EEA07546.1 - 1.4e-23 82.4 0.1 3.8e-05 23.4 0.1 5.1 5 0 0 5 5 5 4 C2 domain PPDK_N PF01326.14 EEA07548.1 - 3.7e-22 78.8 0.0 9.9e-18 64.2 0.0 3.7 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain MA3 PF02847.12 EEA07549.1 - 2e-30 104.7 2.2 4.3e-10 39.2 0.0 4.3 3 1 1 4 4 4 4 MA3 domain Dopey_N PF04118.9 EEA07550.1 - 3e-93 311.9 0.9 3e-93 311.9 0.7 3.8 3 0 0 3 3 3 2 Dopey, N-terminal tRNA_anti-codon PF01336.20 EEA07551.1 - 3.3e-08 33.2 0.8 7.4e-08 32.1 0.6 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4485 PF14846.1 EEA07551.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) E1-E2_ATPase PF00122.15 EEA07554.1 - 1.2e-15 57.1 1.5 1.9e-15 56.5 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA07554.1 - 8.1e-11 42.7 0.0 1.2e-07 32.3 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA07554.1 - 1.4e-06 28.1 0.1 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEA07554.1 - 6.8e-06 26.3 1.0 0.00049 20.3 0.7 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3055 PF11256.3 EEA07554.1 - 0.04 14.0 0.2 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3055) DUF4392 PF14336.1 EEA07554.1 - 0.19 10.4 0.8 0.35 9.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RINGv PF12906.2 EEA07555.1 - 8.6e-12 44.9 5.3 8.6e-12 44.9 3.7 1.4 1 1 0 1 1 1 1 RING-variant domain Peptidase_M50 PF02163.17 EEA07555.1 - 0.0045 15.9 0.1 0.0045 15.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 ABC2_membrane_4 PF12730.2 EEA07555.1 - 0.016 14.3 11.4 0.023 13.8 7.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein NicO PF03824.11 EEA07555.1 - 0.15 11.3 5.6 0.19 11.0 3.8 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SUR7 PF06687.7 EEA07555.1 - 0.68 9.4 7.7 0.89 9.0 5.4 1.1 1 0 0 1 1 1 0 SUR7/PalI family zf-RING_2 PF13639.1 EEA07555.1 - 8.8 6.2 11.7 32 4.4 8.3 1.7 1 1 1 2 2 2 0 Ring finger domain PseudoU_synth_2 PF00849.17 EEA07556.1 - 8.9e-25 87.4 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EEA07556.1 - 0.0059 16.0 0.1 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain UPF0029 PF01205.14 EEA07557.1 - 6.2e-29 99.8 0.0 9e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EEA07557.1 - 0.039 13.8 0.2 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 RWD domain Trm112p PF03966.11 EEA07558.1 - 1.8e-11 44.2 0.1 2.5e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Tox-ART-HYE1 PF15634.1 EEA07558.1 - 0.051 12.5 0.1 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Peptidase_C65 PF10275.4 EEA07561.1 - 6.8e-13 48.5 0.1 8e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C65 PF10275.4 EEA07562.1 - 8.9e-31 107.0 0.2 9.7e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EEA07562.1 - 0.041 14.4 0.0 0.052 14.1 0.0 1.2 1 0 0 1 1 1 0 OTU-like cysteine protease DUF1456 PF07308.8 EEA07562.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Peptidase_M24 PF00557.19 EEA07564.1 - 3.3e-41 141.1 0.0 4.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Baculo_FP PF03258.9 EEA07564.1 - 0.017 14.2 2.4 0.033 13.3 1.7 1.4 1 0 0 1 1 1 0 Baculovirus FP protein DUF3753 PF12575.3 EEA07565.1 - 0.17 11.6 3.4 1.8 8.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) DNA_pol_E_B PF04042.11 EEA07566.1 - 4e-21 75.2 0.3 8.9e-21 74.0 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B GMC_oxred_N PF00732.14 EEA07567.1 - 1.6e-16 60.3 0.3 9.9e-09 34.7 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA07567.1 - 2.2e-09 37.7 0.0 6.9e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEA07567.1 - 1e-05 24.6 0.4 1.6e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA07567.1 - 2.4e-05 24.2 0.6 6e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Use1 PF09753.4 EEA07567.1 - 0.00033 20.1 5.0 0.00064 19.2 3.4 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Pyr_redox_2 PF07992.9 EEA07567.1 - 0.00065 19.6 0.2 0.0024 17.7 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA07567.1 - 0.0017 17.2 0.5 0.0033 16.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEA07567.1 - 0.0022 16.5 0.2 0.0037 15.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 EEA07567.1 - 0.0056 16.1 0.2 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EEA07567.1 - 0.0057 17.0 1.9 0.068 13.5 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA07567.1 - 0.0092 15.0 0.1 0.027 13.5 0.0 1.8 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA07567.1 - 0.012 14.5 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEA07567.1 - 0.057 12.4 0.2 0.087 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EEA07567.1 - 0.078 13.0 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA07567.1 - 4.7 5.9 6.3 0.26 10.0 0.1 2.0 2 1 1 3 3 3 0 Glucose inhibited division protein A DUF4094 PF13334.1 EEA07569.1 - 0.056 13.8 0.4 0.056 13.8 0.3 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 EEA07569.1 - 4.7 7.0 17.7 1.8 8.3 0.2 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Glutaredoxin PF00462.19 EEA07571.1 - 2.7e-14 52.8 0.5 3.7e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EEA07571.1 - 0.00037 20.2 0.7 0.00063 19.5 0.5 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EEA07571.1 - 0.00098 18.6 0.1 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 EEA07571.1 - 0.063 13.5 0.8 0.079 13.2 0.6 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) RRM_DME PF15628.1 EEA07572.1 - 0.0047 16.5 0.0 0.033 13.8 0.0 2.5 2 0 0 2 2 2 1 RRM in Demeter zf-SAP30 PF13866.1 EEA07572.1 - 0.27 10.8 1.2 0.81 9.3 0.9 1.8 1 0 0 1 1 1 0 SAP30 zinc-finger DUF3610 PF12272.3 EEA07576.1 - 0.022 14.4 3.2 1.6 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3610) GPS PF01825.16 EEA07577.1 - 0.015 15.3 8.1 0.056 13.5 1.2 3.0 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain RAP1 PF07218.6 EEA07579.1 - 3.7 5.5 9.9 3.9 5.4 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TFIIA PF03153.8 EEA07579.1 - 4 7.2 21.4 4.3 7.1 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 EEA07579.1 - 9.1 4.5 13.5 9.8 4.4 9.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 EEA07579.1 - 9.4 4.3 20.0 9.6 4.3 13.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Het-C PF07217.6 EEA07582.1 - 0.0046 15.2 0.4 0.0061 14.8 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Nuc_sug_transp PF04142.10 EEA07585.1 - 2.2e-55 187.3 16.1 1.9e-54 184.3 11.2 2.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EEA07585.1 - 3.5e-08 33.6 2.8 3.5e-08 33.6 1.9 3.6 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA07585.1 - 7.1e-08 32.5 6.7 7.1e-08 32.5 4.6 3.4 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 EEA07585.1 - 2e-06 27.5 8.6 2e-06 27.5 6.0 3.2 2 2 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 EEA07585.1 - 0.00035 20.3 8.0 0.054 13.3 0.6 2.7 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 NfeD PF01957.13 EEA07585.1 - 0.018 15.1 0.2 0.018 15.1 0.1 3.4 2 1 3 5 5 5 0 NfeD-like C-terminal, partner-binding PsbL PF02419.12 EEA07585.1 - 0.059 12.7 0.1 0.31 10.5 0.0 2.3 1 0 0 1 1 1 0 PsbL protein E1-E2_ATPase PF00122.15 EEA07586.1 - 3.6e-19 68.7 0.1 3e-18 65.7 0.1 2.5 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EEA07586.1 - 2.9e-12 47.1 0.0 9.5e-12 45.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA07586.1 - 6.8e-09 36.4 0.9 0.00079 19.8 0.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA07586.1 - 0.0057 16.5 0.3 0.016 15.1 0.2 1.8 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF3926 PF13080.1 EEA07586.1 - 0.022 14.2 0.3 0.055 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) OHA PF14418.1 EEA07587.1 - 6.3e-27 92.8 0.0 2.2e-26 91.1 0.0 2.0 1 0 0 1 1 1 1 OST-HTH Associated domain Bromodomain PF00439.20 EEA07588.1 - 1.6e-21 76.0 0.1 3.2e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TPR_MLP1_2 PF07926.7 EEA07589.1 - 0.0011 18.6 15.0 0.0011 18.6 10.4 4.3 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EEA07589.1 - 0.0077 15.3 41.1 0.013 14.5 6.9 3.2 3 0 0 3 3 3 2 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EEA07589.1 - 0.028 13.5 0.9 3.2 6.8 0.1 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein OmpH PF03938.9 EEA07589.1 - 1.2 9.0 37.2 0.68 9.8 6.8 3.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Bacillus_HBL PF05791.6 EEA07589.1 - 3.1 7.1 27.6 0.056 12.8 2.7 3.7 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EEA07589.1 - 3.2 7.3 41.3 1.1 8.8 10.5 4.1 3 1 1 4 4 4 0 IncA protein Lipoprotein_20 PF13942.1 EEA07589.1 - 6.4 6.2 28.0 2.3 7.7 4.5 3.7 4 0 0 4 4 4 0 YfhG lipoprotein Mt_ATP-synt_D PF05873.7 EEA07589.1 - 7.5 6.1 23.3 1.7 8.2 3.9 3.6 3 1 1 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.7 EEA07589.1 - 8.4 6.7 11.9 22 5.3 0.9 4.8 4 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Methyltransf_31 PF13847.1 EEA07590.1 - 3.2e-14 52.7 0.1 6.3e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EEA07590.1 - 7.8e-10 37.9 0.1 1.8e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 EEA07590.1 - 6.9e-07 29.8 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA07590.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07590.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA07590.1 - 0.0006 19.0 0.0 0.00099 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EEA07590.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 EEA07590.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_32 PF13679.1 EEA07590.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEA07590.1 - 0.038 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EEA07590.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase NTP_transf_2 PF01909.18 EEA07592.1 - 0.047 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Mmp37 PF09139.6 EEA07593.1 - 3.7e-25 88.6 1.0 7.4e-24 84.3 0.7 2.1 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 CENP-H PF05837.7 EEA07593.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SMC_N PF02463.14 EEA07594.1 - 7.5e-61 205.1 0.0 2e-60 203.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA07594.1 - 2.1e-21 76.1 0.0 1.1e-20 73.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA07594.1 - 2.7e-14 53.8 21.6 5e-09 36.5 2.8 6.8 1 1 4 6 6 6 2 AAA domain AAA_23 PF13476.1 EEA07594.1 - 6.2e-14 52.8 16.0 6.2e-14 52.8 11.1 7.8 3 2 3 6 6 6 1 AAA domain AAA_29 PF13555.1 EEA07594.1 - 5.2e-08 32.3 0.0 1.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEA07594.1 - 7.6e-05 22.5 0.0 0.0003 20.6 0.0 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EEA07594.1 - 0.0024 18.1 3.3 0.0024 18.1 2.3 6.4 5 3 0 5 5 5 2 ABC transporter AAA_16 PF13191.1 EEA07594.1 - 0.026 14.5 0.2 0.48 10.3 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 EEA07594.1 - 5.4 7.8 14.0 1.6 9.5 0.8 5.0 3 1 0 3 3 3 0 AAA domain Peptidase_M16 PF00675.15 EEA07595.1 - 2e-07 30.9 0.6 5e-07 29.5 0.4 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA07595.1 - 3.4e-06 26.8 0.2 0.00045 19.9 0.1 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Lig_chan-Glu_bd PF10613.4 EEA07595.1 - 0.18 11.8 3.4 0.47 10.4 0.1 3.3 3 0 0 3 3 3 0 Ligated ion channel L-glutamate- and glycine-binding site Sec63 PF02889.11 EEA07596.1 - 2.1e-82 276.8 15.7 3.8e-46 157.7 3.7 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEA07596.1 - 1.1e-51 174.7 0.3 2.7e-24 85.5 0.0 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EEA07596.1 - 4.8e-19 68.8 0.4 5.9e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA07596.1 - 3e-17 62.2 0.0 2.9e-08 33.4 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PhoH PF02562.11 EEA07596.1 - 0.0019 17.5 0.1 1.9 7.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 EEA07596.1 - 0.013 14.9 0.0 6.4 6.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SE PF00437.15 EEA07596.1 - 0.02 13.8 0.0 3.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EEA07596.1 - 0.029 14.1 0.0 6.9 6.4 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain Zeta_toxin PF06414.7 EEA07596.1 - 0.071 12.2 0.0 14 4.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin dCMP_cyt_deam_1 PF00383.17 EEA07597.1 - 3.5e-25 87.6 2.0 6.1e-25 86.8 1.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EEA07597.1 - 7.2e-08 33.2 0.8 3.7e-07 30.9 0.6 2.2 1 1 0 1 1 1 1 AAA domain DUF3278 PF11683.3 EEA07597.1 - 0.002 18.0 4.6 0.0032 17.4 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3278) AAA_18 PF13238.1 EEA07597.1 - 0.0075 16.5 0.9 0.0075 16.5 0.6 2.3 2 1 0 2 2 2 1 AAA domain GRIP PF01465.15 EEA07597.1 - 0.0077 15.7 1.2 0.023 14.2 0.9 1.8 1 0 0 1 1 1 1 GRIP domain AAA_33 PF13671.1 EEA07597.1 - 0.041 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PepSY_2 PF13670.1 EEA07598.1 - 7.2 6.6 9.6 0.11 12.3 0.9 2.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain THUMP PF02926.12 EEA07599.1 - 2.2e-05 24.3 0.5 0.0066 16.3 0.1 2.6 2 0 0 2 2 2 2 THUMP domain SYF2 PF08231.7 EEA07600.1 - 2.8e-08 34.0 7.7 2.8e-08 34.0 5.4 2.1 2 1 0 2 2 2 1 SYF2 splicing factor Pro_isomerase PF00160.16 EEA07600.1 - 2.9e-05 24.3 1.9 9.4e-05 22.6 0.2 2.6 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Endonuc_subdom PF09062.5 EEA07600.1 - 0.11 13.2 0.1 0.11 13.2 0.1 3.2 2 1 1 3 3 3 0 PI-PfuI Endonuclease subdomain Spt4 PF06093.8 EEA07601.1 - 3.8e-30 103.5 0.6 5.2e-30 103.1 0.4 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Methyltransf_11 PF08241.7 EEA07602.1 - 1.3e-17 64.0 0.0 5.8e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA07602.1 - 4.1e-17 62.1 0.9 2e-14 53.4 0.6 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA07602.1 - 1.3e-16 60.7 0.0 1.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA07602.1 - 2e-16 60.2 0.0 4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA07602.1 - 4.8e-12 46.4 0.0 9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07602.1 - 1.1e-06 28.8 0.0 3.7e-06 27.2 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA07602.1 - 2.2e-06 27.6 0.0 3.7e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA07602.1 - 6.7e-05 22.0 0.1 0.0021 17.1 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.6 EEA07602.1 - 9.3e-05 21.9 0.0 0.0011 18.4 0.0 2.0 1 1 1 2 2 2 2 Nodulation protein S (NodS) PrmA PF06325.8 EEA07602.1 - 0.0003 19.9 0.1 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEA07602.1 - 0.00039 19.8 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EEA07602.1 - 0.00044 19.4 0.1 0.13 11.2 0.1 2.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EEA07602.1 - 0.00097 18.5 0.3 0.86 8.9 0.1 2.3 1 1 0 2 2 2 2 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EEA07602.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EEA07602.1 - 0.055 12.1 0.1 2.5 6.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.6 EEA07602.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ank PF00023.25 EEA07603.1 - 5.2e-12 44.9 0.2 4.3e-09 35.7 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEA07603.1 - 9.6e-11 41.8 0.3 4.7e-10 39.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA07603.1 - 1e-08 34.5 2.2 0.00048 20.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEA07603.1 - 9.9e-08 32.3 6.5 7.8e-05 23.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA07603.1 - 1.5e-05 25.0 0.3 0.0004 20.5 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Reo_sigmaC PF04582.7 EEA07603.1 - 0.24 10.5 2.0 0.42 9.7 0.2 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4018 PF13210.1 EEA07604.1 - 0.028 13.8 1.1 0.043 13.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) BAR PF03114.13 EEA07605.1 - 0.13 11.7 4.2 0.49 9.8 2.9 1.9 1 1 0 1 1 1 0 BAR domain DUF4351 PF14261.1 EEA07605.1 - 0.77 9.6 3.7 6.8 6.6 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4351) Fer4_NifH PF00142.13 EEA07605.1 - 1.1 8.4 5.5 1.3 8.1 3.8 1.1 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1154 PF06631.6 EEA07605.1 - 1.2 8.8 4.5 0.84 9.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) TSC22 PF01166.13 EEA07605.1 - 1.5 8.7 5.3 1.7 8.6 2.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2175 PF09943.4 EEA07605.1 - 3.5 7.7 5.6 3.6 7.7 2.9 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) PMC2NT PF08066.7 EEA07605.1 - 8.4 6.7 8.6 6.4 7.1 0.5 2.4 1 1 0 2 2 2 0 PMC2NT (NUC016) domain Ribosomal_S28e PF01200.13 EEA07606.1 - 6.4e-31 105.9 1.7 7.9e-31 105.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e zf-NF-X1 PF01422.12 EEA07606.1 - 0.26 11.2 1.6 0.35 10.8 1.1 1.2 1 0 0 1 1 1 0 NF-X1 type zinc finger DUF2935 PF11155.3 EEA07607.1 - 0.0054 16.8 5.0 0.0054 16.8 3.4 4.9 1 1 2 3 3 3 1 Domain of unknown function (DUF2935) DUF2968 PF11180.3 EEA07607.1 - 0.21 10.9 4.2 5.5 6.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF745 PF05335.8 EEA07607.1 - 3.2 7.2 6.5 8.1 5.9 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MbeD_MobD PF04899.7 EEA07607.1 - 4.3 7.3 7.2 6.2 6.7 0.1 4.0 3 1 0 3 3 3 0 MbeD/MobD like DUF842 PF05811.8 EEA07609.1 - 3.1e-14 52.5 9.6 4.3e-14 52.0 6.1 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF842) Exo5 PF09810.4 EEA07610.1 - 2.1e-68 230.9 6.4 2.8e-68 230.5 4.4 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EEA07610.1 - 0.00013 21.4 1.0 0.0016 17.8 0.7 2.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily TIG PF01833.19 EEA07611.1 - 0.047 13.6 0.1 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 IPT/TIG domain ATP-synt_C PF00137.16 EEA07612.1 - 2.4e-28 97.8 39.6 3.9e-16 58.6 10.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PT-VENN PF04829.8 EEA07612.1 - 0.045 13.3 5.3 0.075 12.5 2.8 2.0 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif Glycophorin_A PF01102.13 EEA07612.1 - 0.25 11.1 3.6 0.58 9.9 2.5 1.6 1 0 0 1 1 1 0 Glycophorin A Nop10p PF04135.7 EEA07613.1 - 4e-21 74.4 0.1 4.7e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family ATP-synt_C PF00137.16 EEA07614.1 - 5.2e-27 93.5 35.1 6.8e-15 54.7 11.1 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.13 EEA07614.1 - 0.15 11.8 1.3 0.33 10.7 0.9 1.5 1 0 0 1 1 1 0 Glycophorin A DUF872 PF05915.7 EEA07614.1 - 2.3 8.1 6.6 0.3 10.9 0.6 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.1 EEA07614.1 - 7.1 6.7 11.6 0.74 9.9 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) zf-C2H2_jaz PF12171.3 EEA07615.1 - 1.3e-09 37.8 3.9 2.2e-09 37.1 2.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEA07615.1 - 0.0026 17.8 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EEA07615.1 - 0.011 15.2 1.2 0.02 14.4 0.8 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-met PF12874.2 EEA07615.1 - 0.21 11.8 1.8 0.35 11.1 1.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Dynamin_M PF01031.15 EEA07619.1 - 6.4e-82 274.6 0.2 1.4e-81 273.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EEA07619.1 - 1.2e-48 165.1 0.5 2.8e-48 163.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EEA07619.1 - 1.8e-23 82.2 0.7 1.8e-23 82.2 0.5 3.0 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEA07619.1 - 0.0051 16.7 0.0 0.028 14.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA07619.1 - 0.0098 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EEA07619.1 - 0.13 11.9 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1804 PF08822.6 EEA07619.1 - 0.13 11.9 0.9 2.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) CDC50 PF03381.10 EEA07620.1 - 1.1e-72 244.5 0.1 2e-72 243.6 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Shisa PF13908.1 EEA07620.1 - 0.066 13.3 0.1 0.066 13.3 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Microtub_assoc PF07989.6 EEA07621.1 - 0.03 14.1 5.3 0.065 13.0 3.1 2.1 1 1 1 2 2 2 0 Microtubule associated IncA PF04156.9 EEA07621.1 - 0.46 10.0 10.3 1.2 8.7 5.1 2.2 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EEA07621.1 - 6.3 7.1 10.7 0.9 9.9 1.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1451 PF07295.6 EEA07622.1 - 0.066 12.9 0.3 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Phage_GPO PF05929.6 EEA07622.1 - 0.086 12.0 0.3 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase bPH_3 PF14470.1 EEA07622.1 - 0.36 11.1 3.2 0.49 10.6 0.5 2.2 2 1 0 2 2 2 0 Bacterial PH domain CBF PF03914.12 EEA07623.1 - 3.2e-23 81.9 3.9 4.4e-23 81.5 1.3 2.4 2 0 0 2 2 2 1 CBF/Mak21 family MRAP PF15183.1 EEA07624.1 - 0.093 12.3 2.0 1.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family RRM_1 PF00076.17 EEA07625.1 - 5.2e-08 32.4 0.1 1.1e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07625.1 - 2.2e-07 30.7 0.0 4.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07625.1 - 0.0032 17.2 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ PF12752.2 EEA07625.1 - 1.1 9.8 0.1 1.1 9.8 0.0 3.9 4 1 0 4 4 4 0 SUZ domain ELM2 PF01448.19 EEA07626.1 - 5.5e-05 23.7 0.3 5.5e-05 23.7 0.2 1.7 2 1 0 2 2 2 1 ELM2 domain Patatin PF01734.17 EEA07627.1 - 1.4e-19 70.8 0.4 1.4e-17 64.3 0.3 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase EF-hand_1 PF00036.27 EEA07628.1 - 1.7e-19 67.5 3.7 6.5e-06 25.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEA07628.1 - 2.1e-17 61.3 4.6 2.4e-06 26.9 0.1 4.1 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EEA07628.1 - 1e-15 57.5 5.7 3.1e-10 40.0 1.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA07628.1 - 1.6e-15 55.6 5.7 5.6e-05 22.3 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EEA07628.1 - 2.2e-15 55.9 4.1 3.8e-07 29.6 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EEA07628.1 - 3.8e-06 26.7 0.5 0.23 11.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 EEA07628.1 - 6.4e-05 22.6 1.3 0.071 12.8 0.4 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EEA07628.1 - 0.011 15.2 0.1 0.056 12.9 0.1 2.3 1 1 1 2 2 2 0 Caleosin related protein VCBS PF13517.1 EEA07628.1 - 0.048 14.0 0.2 17 5.8 0.0 2.8 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PTS_2-RNA PF01885.11 EEA07628.1 - 0.056 12.7 0.0 0.31 10.3 0.0 2.1 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family GatB_Yqey PF02637.13 EEA07628.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 GatB domain SPARC_Ca_bdg PF10591.4 EEA07628.1 - 0.13 12.3 0.6 5.8 6.9 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 EEA07629.1 - 2.5e-32 109.5 26.0 1.9e-09 37.0 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEA07629.1 - 0.14 11.9 0.1 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 EEA07629.1 - 3.5 5.3 4.2 2.2 5.9 0.1 2.2 2 1 0 2 2 2 0 IKI3 family HA2 PF04408.18 EEA07630.1 - 1.2e-29 102.3 0.1 3.8e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEA07630.1 - 2.5e-25 88.5 0.1 5e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEA07630.1 - 8.5e-10 38.3 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA07630.1 - 3.5e-08 33.1 0.1 7.1e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA07630.1 - 1.5e-06 28.3 1.2 5.3e-06 26.6 0.1 2.4 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EEA07630.1 - 0.00041 19.9 0.3 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Flavi_DEAD PF07652.9 EEA07630.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EEA07630.1 - 0.0018 18.1 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEA07630.1 - 0.015 14.5 0.1 0.12 11.6 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein SRP54 PF00448.17 EEA07630.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EEA07630.1 - 0.021 13.9 0.0 0.066 12.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Zot PF05707.7 EEA07630.1 - 0.027 13.9 0.3 0.058 12.8 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 EEA07630.1 - 0.031 14.5 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EEA07630.1 - 0.034 14.4 0.2 0.034 14.4 0.1 2.8 2 1 1 3 3 3 0 AAA domain KaiC PF06745.8 EEA07630.1 - 0.035 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EEA07630.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEA07630.1 - 0.038 12.9 0.0 0.089 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EEA07630.1 - 0.063 13.1 2.5 0.56 10.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EEA07630.1 - 0.074 13.2 0.2 0.4 10.8 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEA07630.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA07630.1 - 0.19 11.1 0.0 1.2 8.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Amnionless PF14828.1 EEA07631.1 - 0.12 10.7 1.0 0.2 10.1 0.7 1.3 1 0 0 1 1 1 0 Amnionless Glyco_tran_28_C PF04101.11 EEA07632.1 - 7.9e-24 84.1 0.0 9.8e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain WD40 PF00400.27 EEA07633.1 - 3.1e-15 55.3 12.5 6.6e-05 22.6 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat TIMELESS_C PF05029.8 EEA07634.1 - 3.6e-09 36.1 1.3 1.4e-06 27.5 0.1 2.9 4 0 0 4 4 4 2 Timeless protein C terminal region PCI PF01399.22 EEA07635.1 - 5e-17 62.1 2.3 2e-16 60.2 0.0 3.0 2 1 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 EEA07635.1 - 7.7e-08 32.6 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 EEA07635.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.8 1 1 1 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EEA07635.1 - 0.077 12.9 0.8 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA07635.1 - 2.7 7.9 9.4 12 5.8 2.8 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.16 EEA07636.1 - 3.1e-17 61.6 6.9 3.4e-17 61.5 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EEA07636.1 - 0.52 10.4 3.7 2.2 8.4 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase IGFBP PF00219.13 EEA07636.1 - 0.88 10.1 5.4 4.1 8.0 3.7 1.8 1 1 1 2 2 2 0 Insulin-like growth factor binding protein Ribosomal_L40e PF01020.12 EEA07636.1 - 2.9 7.5 9.2 6 6.5 1.6 2.2 1 1 1 2 2 2 0 Ribosomal L40e family DUF1289 PF06945.8 EEA07636.1 - 3.3 7.2 7.7 13 5.3 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1289) Clat_adaptor_s PF01217.15 EEA07637.1 - 2.2e-51 173.3 4.2 2.5e-51 173.1 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Filamin PF00630.14 EEA07638.1 - 5.6e-24 84.6 0.1 7.8e-18 64.9 0.0 3.4 3 0 0 3 3 3 2 Filamin/ABP280 repeat tRNA-synt_His PF13393.1 EEA07640.1 - 1.2e-43 149.3 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EEA07640.1 - 7e-19 68.0 0.0 1.6e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA07640.1 - 8.8e-14 51.2 0.0 4.1e-13 49.0 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEA07640.1 - 5e-07 28.7 0.0 5.3e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EEA07640.1 - 0.0049 16.1 0.0 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) cNMP_binding PF00027.24 EEA07641.1 - 4.2e-36 122.6 0.1 5.4e-09 35.7 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain MerR-DNA-bind PF09278.6 EEA07641.1 - 0.0076 16.6 0.1 1.8 8.9 0.0 3.0 3 0 0 3 3 3 1 MerR, DNA binding HALZ PF02183.13 EEA07642.1 - 0.13 12.0 11.2 1.4 8.7 0.1 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper Microtub_assoc PF07989.6 EEA07642.1 - 0.58 10.0 6.2 0.48 10.2 0.2 3.5 3 1 1 4 4 4 0 Microtubule associated TSC22 PF01166.13 EEA07642.1 - 0.69 9.9 7.1 0.99 9.4 0.0 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family NAP PF00956.13 EEA07643.1 - 1.5e-25 89.7 6.1 2.1e-25 89.2 4.2 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.3 EEA07643.1 - 0.023 14.5 1.7 0.066 13.0 1.2 1.8 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Utp11 PF03998.8 EEA07643.1 - 0.34 10.6 4.7 0.32 10.7 0.1 1.9 1 1 0 2 2 2 0 Utp11 protein WD40 PF00400.27 EEA07644.1 - 2.4e-08 33.5 6.9 0.26 11.2 0.0 6.5 7 1 0 7 7 7 3 WD domain, G-beta repeat DUF3312 PF11768.3 EEA07644.1 - 0.00025 19.3 0.0 0.0018 16.6 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 EEA07644.1 - 0.011 15.4 0.0 0.94 9.1 0.0 2.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ricin_B_lectin PF00652.17 EEA07644.1 - 0.057 13.4 0.1 0.41 10.6 0.0 2.1 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain MutS_V PF00488.16 EEA07645.1 - 6.3e-83 277.7 0.1 1.2e-82 276.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA07645.1 - 2.6e-30 105.7 1.5 2.6e-30 105.7 1.0 3.0 4 0 0 4 4 4 1 MutS domain III MutS_II PF05188.12 EEA07645.1 - 0.001 19.1 2.9 0.0017 18.3 0.1 2.9 4 0 0 4 4 4 1 MutS domain II DUF2884 PF11101.3 EEA07645.1 - 0.0083 15.5 0.3 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) AAA_29 PF13555.1 EEA07645.1 - 0.025 14.1 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIH_BTF_p62_N PF08567.6 EEA07645.1 - 0.09 12.4 0.1 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain AAA_23 PF13476.1 EEA07645.1 - 0.69 10.2 0.0 0.69 10.2 0.0 4.4 3 1 1 4 4 4 0 AAA domain NTP_transferase PF00483.18 EEA07646.1 - 4.3e-17 62.2 0.0 1.2e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EEA07646.1 - 6.8e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EEA07646.1 - 3.2e-08 32.6 13.7 0.0042 16.5 0.2 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EEA07646.1 - 0.00053 18.6 0.6 0.00092 17.8 0.4 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.1 EEA07646.1 - 0.017 14.6 15.8 1.1 8.8 1.0 3.9 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 EEA07647.1 - 1.4e-09 38.0 1.3 6.2e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EEA07647.1 - 3.6e-08 33.3 0.0 1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA07647.1 - 1.9e-06 27.4 0.0 5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEA07647.1 - 0.0036 16.5 0.1 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EEA07647.1 - 0.0069 16.8 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EEA07647.1 - 0.0072 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EEA07647.1 - 0.016 14.6 0.5 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EEA07647.1 - 0.035 13.0 0.1 0.08 11.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 EEA07647.1 - 0.037 13.2 1.3 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EEA07647.1 - 0.037 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EEA07647.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EEA07647.1 - 0.065 12.8 1.0 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EEA07647.1 - 0.18 11.2 0.0 0.62 9.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Reticulon PF02453.12 EEA07648.1 - 3.1 7.3 6.3 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Reticulon MFS_1 PF07690.11 EEA07649.1 - 1.4e-42 145.7 23.5 2.8e-41 141.4 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 EEA07650.1 - 1.9e-34 118.6 0.2 3.3e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA07650.1 - 7.7e-26 89.7 0.4 4.9e-25 87.1 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA07650.1 - 0.0022 17.8 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA07650.1 - 0.024 13.7 0.1 0.046 12.7 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ChaC PF04752.7 EEA07650.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ChaC-like protein Aa_trans PF01490.13 EEA07651.1 - 9.9e-16 57.2 37.9 1.4e-11 43.5 15.9 2.9 2 1 1 3 3 3 3 Transmembrane amino acid transporter protein YokU PF14122.1 EEA07651.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 YokU-like protein Patatin PF01734.17 EEA07652.1 - 6.7e-10 39.2 0.0 9.2e-09 35.5 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EEA07653.1 - 2.9e-23 82.8 0.0 6.4e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase UQ_con PF00179.21 EEA07656.1 - 1.4e-17 63.4 0.1 3.8e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA07656.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain Baculo_11_kDa PF06143.6 EEA07656.1 - 1.3 8.3 4.7 2.7 7.4 3.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family CHASE3 PF05227.8 EEA07657.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 CHASE3 domain LON PF02190.11 EEA07657.1 - 0.054 13.1 3.1 0.076 12.6 2.1 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DNA_gyraseB PF00204.20 EEA07657.1 - 0.088 12.0 2.0 0.13 11.4 1.4 1.3 1 0 0 1 1 1 0 DNA gyrase B zf-DHHC PF01529.15 EEA07658.1 - 1.2 8.4 3.2 3.2 7.1 2.2 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF2036 PF09724.4 EEA07659.1 - 1.2e-24 87.0 3.1 1.2e-12 47.6 1.4 3.1 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) PA28_alpha PF02251.13 EEA07659.1 - 0.14 12.3 1.5 11 6.2 0.3 2.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit TRAUB PF08164.7 EEA07660.1 - 4.9e-17 61.7 0.0 1.4e-16 60.3 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EEA07660.1 - 6.7e-13 48.9 0.3 3.1e-12 46.7 0.0 2.3 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor CRAL_TRIO PF00650.15 EEA07661.1 - 2.7e-32 111.4 0.3 3.8e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA07661.1 - 7.5e-07 29.1 0.1 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IQ PF00612.22 EEA07661.1 - 0.0037 16.7 0.0 0.0092 15.5 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SNARE PF05739.14 EEA07662.1 - 1.9e-05 24.2 0.6 3.8e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 SNARE domain DnaJ PF00226.26 EEA07663.1 - 3.8e-25 87.4 2.2 7.4e-25 86.4 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEA07663.1 - 1.4e-22 79.3 2.4 1.1e-21 76.4 0.1 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEA07663.1 - 4.8e-15 55.3 15.6 9.2e-15 54.4 10.8 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF2112 PF09885.4 EEA07663.1 - 0.12 12.0 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) HypA PF01155.14 EEA07663.1 - 1.1 8.9 9.2 3.9 7.2 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF4399 PF14347.1 EEA07664.1 - 0.0074 16.2 0.8 13 5.9 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4399) REV PF00424.13 EEA07665.1 - 0.32 10.9 0.0 0.32 10.9 0.0 3.5 2 1 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Prp31_C PF09785.4 EEA07665.1 - 1.2 9.6 5.3 12 6.2 0.0 3.1 3 1 0 3 3 3 0 Prp31 C terminal domain Aa_trans PF01490.13 EEA07666.1 - 1.9e-57 194.5 42.8 2.2e-57 194.3 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEA07666.1 - 6.6e-07 28.4 27.7 6.6e-07 28.4 19.2 2.1 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family RapA_C PF12137.3 EEA07667.1 - 0.044 12.6 2.8 0.065 12.0 2.0 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Archease PF01951.11 EEA07667.1 - 0.053 13.4 0.2 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) Swi5 PF07061.6 EEA07667.1 - 0.51 10.1 3.9 1.2 8.9 2.7 1.7 1 0 0 1 1 1 0 Swi5 zf-CCHC_2 PF13696.1 EEA07668.1 - 1.5e-06 27.5 0.4 3.5e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EEA07668.1 - 3.2e-05 23.8 10.3 3.2e-05 23.8 7.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07668.1 - 0.00057 19.6 9.3 0.00057 19.6 6.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA07668.1 - 0.0053 16.4 8.0 0.0053 16.4 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DWNN PF08783.6 EEA07668.1 - 0.016 15.1 0.0 0.055 13.4 0.0 2.0 1 0 0 1 1 1 0 DWNN domain FANCL_C PF11793.3 EEA07668.1 - 0.3 11.0 5.2 0.93 9.5 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EEA07668.1 - 0.5 10.2 13.1 0.24 11.2 6.6 2.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EEA07668.1 - 1.7 8.5 8.3 61 3.4 5.8 2.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EEA07668.1 - 1.8 8.3 17.0 0.11 12.2 6.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain FTR_C PF02741.10 EEA07670.1 - 0.0009 19.0 0.3 0.0011 18.7 0.2 1.1 1 0 0 1 1 1 1 FTR, proximal lobe Nop25 PF09805.4 EEA07670.1 - 0.0014 18.6 9.1 0.0016 18.4 6.3 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) RabGAP-TBC PF00566.13 EEA07670.1 - 0.11 11.8 1.4 0.14 11.6 1.0 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ribosomal_S8 PF00410.14 EEA07670.1 - 3.6 7.4 7.0 5 6.9 4.5 1.5 1 1 0 1 1 1 0 Ribosomal protein S8 DIM1 PF02966.11 EEA07672.1 - 3.6e-64 214.2 0.3 4e-64 214.0 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EEA07672.1 - 0.02 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Carboxyl_trans PF01039.17 EEA07673.1 - 5.1e-135 450.6 0.0 6.9e-135 450.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEA07673.1 - 1.1e-47 162.0 0.8 2.1e-47 161.1 0.6 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.7 EEA07673.1 - 4.2e-37 127.6 4.9 6.7e-22 77.4 0.0 3.8 3 1 0 3 3 3 3 Acetyl-CoA carboxylase, central region CPSase_L_chain PF00289.17 EEA07673.1 - 1.8e-23 82.7 0.0 5.6e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEA07673.1 - 1.2e-19 70.3 0.0 3.2e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EEA07673.1 - 5.4e-12 45.8 0.0 1.4e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEA07673.1 - 1e-07 31.4 0.0 2.7e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EEA07673.1 - 3.7e-07 29.7 0.2 8.8e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEA07673.1 - 1.1e-06 28.6 0.5 2.4e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EEA07673.1 - 4e-05 23.0 0.1 8.3e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HPPK PF01288.15 EEA07674.1 - 0.092 12.4 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RTC PF01137.16 EEA07675.1 - 2.2e-43 147.6 0.0 2.6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EEA07675.1 - 1.1e-13 51.0 0.0 2.5e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF974 PF06159.8 EEA07676.1 - 1.1e-14 54.4 0.3 1.5e-14 54.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 EEA07676.1 - 0.0016 17.8 1.4 0.56 9.4 0.0 2.3 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.17 EEA07676.1 - 0.0099 15.8 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Transglutaminase family, C-terminal ig like domain fn3 PF00041.16 EEA07676.1 - 0.15 12.2 0.3 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Fibronectin type III domain Patched PF02460.13 EEA07677.1 - 1.1e-24 86.5 42.3 1.8e-13 49.3 13.1 4.1 3 1 1 4 4 4 4 Patched family Sterol-sensing PF12349.3 EEA07677.1 - 6.6e-11 41.8 25.5 1.1e-10 41.2 0.2 3.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation UFC1 PF08694.6 EEA07678.1 - 2.5e-72 241.6 0.9 2.8e-72 241.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 EEA07678.1 - 0.00061 19.2 1.3 0.0034 16.8 0.9 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA07678.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA07678.1 - 0.036 13.9 0.2 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 RWD domain Defensin_4 PF07936.7 EEA07678.1 - 2.3 7.9 6.0 0.35 10.5 1.5 1.6 2 0 0 2 2 2 0 Potassium-channel blocking toxin DUF3270 PF11674.3 EEA07679.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) Reo_sigmaC PF04582.7 EEA07681.1 - 0.0046 16.1 1.2 0.008 15.3 0.8 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Ribosomal_L11_N PF03946.9 EEA07682.1 - 0.13 11.7 0.1 1.7 8.1 0.0 2.6 2 1 1 3 3 3 0 Ribosomal protein L11, N-terminal domain CYSTM PF12734.2 EEA07683.1 - 0.071 13.1 2.5 0.14 12.2 1.8 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance PITH PF06201.8 EEA07688.1 - 2.5e-31 108.5 1.0 2.8e-31 108.3 0.7 1.0 1 0 0 1 1 1 1 PITH domain TetR_C_8 PF14278.1 EEA07690.1 - 0.033 14.5 2.0 0.033 14.5 1.4 4.5 4 2 2 6 6 6 0 Transcriptional regulator C-terminal region Ribosomal_L18_c PF14204.1 EEA07690.1 - 0.58 10.7 6.0 7.4 7.2 1.9 2.7 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Ribosomal_L34e PF01199.13 EEA07692.1 - 9.9e-35 118.6 6.1 9.9e-35 118.6 4.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e Atg14 PF10186.4 EEA07692.1 - 0.006 15.5 1.9 0.0069 15.3 1.3 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4316 PF14195.1 EEA07692.1 - 0.11 12.5 1.7 0.14 12.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) zf-RING_2 PF13639.1 EEA07693.1 - 7.3e-12 44.9 12.6 1.3e-11 44.1 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA07693.1 - 1.7e-07 31.2 7.2 4.1e-07 30.0 5.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA07693.1 - 2.9e-05 23.6 11.6 5.6e-05 22.7 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07693.1 - 3.8e-05 23.6 13.4 7e-05 22.7 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07693.1 - 4e-05 23.2 8.8 6.3e-05 22.5 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07693.1 - 0.00018 21.1 10.0 0.00031 20.3 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA07693.1 - 0.0066 16.2 6.2 0.021 14.6 4.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EEA07693.1 - 0.018 15.0 0.8 0.036 14.0 0.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 EEA07693.1 - 0.26 11.0 9.6 0.5 10.0 6.7 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EEA07693.1 - 0.72 9.6 7.2 0.68 9.7 2.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 tRNA-synt_1g PF09334.6 EEA07694.1 - 6.1e-106 354.3 2.7 4.3e-104 348.2 1.9 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEA07694.1 - 3.7e-35 121.0 3.9 1e-19 69.9 0.1 3.9 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EEA07694.1 - 1.2e-10 41.0 0.3 1.9e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EEA07694.1 - 8.6e-05 21.3 0.1 0.12 11.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.8 EEA07694.1 - 0.0019 17.9 0.1 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1b PF00579.20 EEA07694.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Dicistro_VP4 PF11492.3 EEA07694.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Coiled-coil_56 PF09813.4 EEA07694.1 - 0.16 11.9 0.1 0.42 10.6 0.0 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 Ribosomal_L22 PF00237.14 EEA07695.1 - 2.7e-27 94.7 0.0 3.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HEAT PF02985.17 EEA07696.1 - 1.1e-19 68.6 11.0 1.9e-05 24.3 0.0 10.2 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 EEA07696.1 - 6.1e-16 58.3 1.3 8.3e-09 35.6 0.0 6.8 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.1 EEA07696.1 - 3.5e-14 52.8 0.0 7.2e-07 29.4 0.0 5.6 4 3 2 6 6 6 4 HEAT repeats CLASP_N PF12348.3 EEA07696.1 - 1.6e-08 34.2 2.9 0.0032 16.8 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.2 EEA07696.1 - 2.5e-06 27.4 9.7 0.0081 16.0 0.1 5.3 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EEA07696.1 - 7.8e-06 24.4 2.7 0.002 16.5 0.3 4.2 2 2 1 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EEA07696.1 - 0.00024 21.4 0.0 3.6 8.0 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EEA07696.1 - 0.0013 18.6 0.3 0.039 13.8 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1546 PF07571.8 EEA07696.1 - 0.0015 18.6 0.0 13 5.9 0.0 4.3 3 2 1 4 4 4 1 Protein of unknown function (DUF1546) DUF1298 PF06974.8 EEA07697.1 - 4.8e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) SNARE PF05739.14 EEA07698.1 - 8.7e-12 44.5 0.8 8.7e-12 44.5 0.5 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 EEA07698.1 - 3.2e-05 24.2 4.3 0.087 13.2 0.1 3.1 2 1 0 2 2 2 2 Syntaxin 6, N-terminal MCPsignal PF00015.16 EEA07698.1 - 0.00024 20.7 4.6 0.00036 20.1 1.2 2.0 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain SF-assemblin PF06705.6 EEA07698.1 - 0.0027 16.8 5.2 0.038 13.1 0.3 2.3 2 0 0 2 2 2 2 SF-assemblin/beta giardin Katanin_con80 PF13925.1 EEA07698.1 - 0.013 15.2 1.1 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 con80 domain of Katanin Cob_adeno_trans PF01923.13 EEA07698.1 - 0.014 15.1 0.6 0.55 10.0 0.1 2.5 2 1 0 2 2 2 0 Cobalamin adenosyltransferase RmuC PF02646.11 EEA07698.1 - 0.017 13.9 4.6 0.41 9.4 0.2 2.3 2 0 0 2 2 2 0 RmuC family DUF239 PF03080.10 EEA07698.1 - 0.021 13.9 0.2 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF239) Mer2 PF09074.5 EEA07698.1 - 0.026 14.4 4.7 4.5 7.1 0.5 3.0 2 1 1 3 3 3 0 Mer2 XH PF03469.9 EEA07698.1 - 0.036 13.7 0.4 0.13 11.9 0.0 2.0 2 1 0 2 2 2 0 XH domain Cytochrom_B562 PF07361.6 EEA07698.1 - 0.076 13.4 0.7 1.1 9.7 0.0 2.7 2 1 1 3 3 3 0 Cytochrome b562 Corona_S2 PF01601.11 EEA07698.1 - 0.085 10.9 4.9 0.014 13.5 0.9 1.4 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein IFT57 PF10498.4 EEA07698.1 - 0.11 11.2 5.0 0.14 10.8 0.3 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.7 EEA07698.1 - 0.12 12.2 6.1 0.81 9.5 0.5 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3595 PF12166.3 EEA07698.1 - 0.24 10.1 4.5 0.13 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) DUF948 PF06103.6 EEA07698.1 - 0.49 10.2 2.2 9.8 6.1 0.2 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 EEA07698.1 - 0.64 7.4 8.3 0.1 10.1 1.7 2.1 1 1 0 2 2 2 0 Prominin Fib_alpha PF08702.5 EEA07698.1 - 1.9 8.5 11.5 4.4 7.4 1.4 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Cyclin_N PF00134.18 EEA07699.1 - 3.8e-05 23.2 5.3 0.00014 21.4 0.8 3.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA07699.1 - 0.0038 17.1 2.1 0.0055 16.6 0.3 2.2 2 1 1 3 3 3 1 Cyclin, C-terminal domain DUF4332 PF14229.1 EEA07699.1 - 0.0079 16.1 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4332) FGGY_N PF00370.16 EEA07699.1 - 0.06 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Cyclin_N PF00134.18 EEA07700.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain HA2 PF04408.18 EEA07701.1 - 2.3e-25 88.5 0.1 1.2e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEA07701.1 - 5.6e-21 74.4 0.1 1.5e-20 73.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEA07701.1 - 2.5e-10 40.0 0.0 5.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA07701.1 - 4.6e-09 35.9 0.0 9.8e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA07701.1 - 9.7e-06 25.7 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EEA07701.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EEA07701.1 - 0.0012 17.7 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EEA07701.1 - 0.0036 17.2 0.1 0.038 13.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA07701.1 - 0.0073 15.9 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA07701.1 - 0.01 15.2 0.0 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EEA07701.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EEA07701.1 - 0.027 13.8 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 EEA07701.1 - 0.087 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Methyltransf_11 PF08241.7 EEA07702.1 - 4.7e-13 49.4 0.0 1.5e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA07702.1 - 1.1e-10 41.3 0.2 1.8e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA07702.1 - 8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07702.1 - 2.2e-09 37.6 0.1 7e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA07702.1 - 1.5e-07 31.8 0.9 2.8e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA07702.1 - 6.5e-05 23.4 0.1 0.00018 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA07702.1 - 0.00075 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EEA07702.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 EEA07702.1 - 0.0037 16.8 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EEA07702.1 - 0.0048 16.3 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 EEA07702.1 - 0.006 15.7 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB N6_N4_Mtase PF01555.13 EEA07702.1 - 0.011 15.2 1.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltransf_9 PF08003.6 EEA07702.1 - 0.053 12.2 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CRAL_TRIO PF00650.15 EEA07703.1 - 1.7e-20 73.1 0.8 3e-20 72.3 0.5 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA07703.1 - 0.0026 17.6 1.3 0.0044 16.9 0.9 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.1 EEA07703.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.11 EEA07703.1 - 0.059 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 CUE domain DUF1382 PF07131.6 EEA07703.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) YkyA PF10368.4 EEA07703.1 - 0.87 8.8 6.7 0.19 11.0 1.3 2.1 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Pkinase PF00069.20 EEA07705.1 - 5.2e-09 35.6 1.7 5.6e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07705.1 - 2e-06 27.0 0.0 5.5e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Uteroglobin PF01099.12 EEA07705.1 - 0.02 14.6 0.6 0.082 12.7 0.4 2.0 1 0 0 1 1 1 0 Uteroglobin family YlqD PF11068.3 EEA07705.1 - 0.028 14.4 6.4 0.091 12.7 4.4 1.8 1 0 0 1 1 1 0 YlqD protein COG5 PF10392.4 EEA07705.1 - 0.077 12.9 3.5 0.21 11.5 0.6 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Prefoldin PF02996.12 EEA07705.1 - 0.084 12.5 10.6 0.066 12.8 2.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit Apolipoprotein PF01442.13 EEA07705.1 - 0.13 11.8 1.8 1.5 8.2 1.3 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4140 PF13600.1 EEA07705.1 - 0.18 12.2 2.5 15 6.1 0.3 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1512 PF07431.7 EEA07705.1 - 0.41 9.3 2.3 0.66 8.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF1664 PF07889.7 EEA07705.1 - 2.8 7.7 5.7 3.1 7.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EEA07705.1 - 4.5 6.8 7.7 20 4.6 5.3 2.1 1 1 0 1 1 1 0 IncA protein TPR_11 PF13414.1 EEA07707.1 - 2.7e-13 49.3 1.2 9.1e-13 47.6 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEA07707.1 - 3.2e-07 29.6 0.1 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA07707.1 - 0.00021 20.9 0.0 0.03 14.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.4 EEA07707.1 - 0.0084 14.7 0.2 0.012 14.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_17 PF13431.1 EEA07707.1 - 0.052 13.7 0.4 2.8 8.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 EEA07708.1 - 1.8e-38 129.0 10.6 7.7e-10 38.2 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEA07708.1 - 0.09 12.2 0.5 13 5.3 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PIG-U PF06728.8 EEA07710.1 - 8.6e-71 238.8 48.5 1e-70 238.5 33.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Prefoldin_2 PF01920.15 EEA07711.1 - 5.2e-14 51.8 7.1 6e-14 51.7 4.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Uds1 PF15456.1 EEA07711.1 - 0.01 15.8 0.9 0.013 15.5 0.6 1.1 1 0 0 1 1 1 0 Up-regulated During Septation DUF2340 PF10209.4 EEA07711.1 - 0.02 15.0 4.9 0.044 13.9 3.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) FH2 PF02181.18 EEA07711.1 - 0.023 13.5 2.9 0.075 11.9 0.1 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain Seryl_tRNA_N PF02403.17 EEA07711.1 - 0.028 14.4 4.1 0.92 9.5 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EEA07711.1 - 0.055 13.2 1.9 2.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_12 PF13087.1 EEA07711.1 - 0.079 12.3 0.7 0.094 12.0 0.5 1.2 1 0 0 1 1 1 0 AAA domain DivIVA PF05103.8 EEA07711.1 - 0.12 12.4 3.8 0.23 11.5 2.6 1.4 1 1 0 1 1 1 0 DivIVA protein BLOC1_2 PF10046.4 EEA07711.1 - 0.14 12.2 5.1 0.41 10.7 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ubiquitin_2 PF14560.1 EEA07711.1 - 0.15 12.3 2.1 1.6 9.0 0.4 2.4 2 1 0 2 2 2 0 Ubiquitin-like domain DUF4014 PF13198.1 EEA07711.1 - 0.2 12.0 1.2 8.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DUF972 PF06156.8 EEA07711.1 - 0.22 11.8 3.8 2.4 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) P4Ha_N PF08336.6 EEA07711.1 - 0.31 10.8 4.4 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.5 EEA07711.1 - 0.8 9.8 5.3 5.2 7.1 3.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 EEA07711.1 - 0.94 9.1 6.9 7.6 6.2 3.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.1 EEA07711.1 - 1.4 9.2 4.7 2.8 8.3 0.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin FliD_N PF02465.13 EEA07711.1 - 3.1 8.2 6.9 12 6.3 1.7 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pro_isomerase PF00160.16 EEA07712.1 - 1e-47 162.1 0.5 3.2e-47 160.6 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EEA07712.1 - 2.5e-09 36.6 10.3 0.026 14.4 1.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEA07712.1 - 0.049 13.1 0.8 0.82 9.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIS_C PF01096.13 EEA07713.1 - 2.4e-22 78.2 3.1 2.4e-22 78.2 2.2 2.9 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.5 EEA07713.1 - 1.3e-06 28.2 3.0 0.00095 19.0 0.1 2.2 1 1 1 2 2 2 2 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 EEA07713.1 - 1.9e-06 27.5 6.0 0.00054 19.7 0.5 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EEA07713.1 - 3.1e-05 23.5 0.3 3.1e-05 23.5 0.2 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 EEA07713.1 - 0.00083 18.6 5.0 0.0062 15.8 0.2 2.5 2 1 0 2 2 2 1 TFIIB zinc-binding Baculo_LEF5_C PF11792.3 EEA07713.1 - 0.035 13.5 0.0 0.035 13.5 0.0 3.2 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain zf-CHY PF05495.7 EEA07713.1 - 0.043 13.9 8.5 18 5.5 5.9 2.4 1 1 0 1 1 1 0 CHY zinc finger Inhibitor_I29 PF08246.7 EEA07713.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) zf-ribbon_3 PF13248.1 EEA07713.1 - 0.086 12.0 11.3 0.098 11.8 1.0 3.2 3 1 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EEA07713.1 - 0.099 12.4 0.6 0.099 12.4 0.4 2.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Thioredoxin_3 PF13192.1 EEA07713.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.8 2 1 2 4 4 3 0 Thioredoxin domain DZR PF12773.2 EEA07713.1 - 0.11 12.3 12.2 16 5.4 8.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EEA07713.1 - 0.18 11.8 5.5 6.6 6.8 0.1 3.6 4 0 0 4 4 4 0 zinc-finger DUF164 PF02591.10 EEA07713.1 - 0.25 11.2 8.4 2.3 8.0 0.0 3.2 4 0 0 4 4 4 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 EEA07713.1 - 0.26 11.2 9.6 6.4 6.8 0.0 3.7 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EEA07713.1 - 0.38 10.3 10.8 4.3 7.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EEA07713.1 - 0.42 10.1 0.2 0.42 10.1 0.1 3.0 4 0 0 4 4 4 0 InsA N-terminal domain Tmemb_55A PF09788.4 EEA07713.1 - 0.76 8.8 4.4 3.8 6.5 2.0 2.0 1 1 1 2 2 2 0 Transmembrane protein 55A PHD PF00628.24 EEA07713.1 - 0.87 9.3 8.9 4.3 7.1 0.3 3.0 2 1 1 3 3 3 0 PHD-finger Opy2 PF09463.5 EEA07713.1 - 1.1 9.4 7.5 30 4.7 0.0 3.9 4 0 0 4 4 4 0 Opy2 protein DUF2082 PF09855.4 EEA07713.1 - 1.4 8.7 8.2 2.4 8.0 0.0 3.4 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DNA_ligase_ZBD PF03119.11 EEA07713.1 - 1.5 8.5 0.1 1.5 8.5 0.0 2.7 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain Lar_restr_allev PF14354.1 EEA07713.1 - 1.8 8.9 7.2 2.9 8.2 0.7 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 EEA07713.1 - 2.5 7.6 0.0 2.5 7.6 0.0 3.6 3 1 0 3 3 3 0 A2L zinc ribbon domain Terminase_GpA PF05876.7 EEA07713.1 - 2.9 6.1 6.0 0.29 9.4 1.1 1.6 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zf-B_box PF00643.19 EEA07713.1 - 2.9 7.8 11.3 5.2 7.0 1.2 3.1 3 0 0 3 3 3 0 B-box zinc finger RecR PF02132.10 EEA07713.1 - 3.5 7.1 6.8 2.7 7.4 0.3 3.1 3 0 0 3 3 3 0 RecR protein zf-C4_Topoisom PF01396.14 EEA07713.1 - 4.3 6.9 6.6 15 5.2 0.4 3.1 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc-ribbons_6 PF07191.7 EEA07713.1 - 5 6.9 10.0 3.5 7.4 0.5 3.0 1 1 0 2 2 2 0 zinc-ribbons DUF2296 PF10058.4 EEA07713.1 - 5.2 6.9 11.9 4.9 6.9 1.7 3.5 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-TFIIB PF13453.1 EEA07713.1 - 6 6.1 11.9 0.31 10.2 0.8 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.1 EEA07713.1 - 6.3 6.5 15.6 2.7 7.7 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 EEA07713.1 - 6.6 6.6 13.0 4.6e+03 -2.5 9.0 2.9 1 1 0 1 1 0 0 IBR domain RPA_interact_C PF14768.1 EEA07713.1 - 7.2 7.0 9.9 2e+02 2.4 6.8 2.6 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Tnp_zf-ribbon_2 PF13842.1 EEA07713.1 - 8.2 6.9 11.8 2.5 8.5 0.4 3.1 2 2 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Fer4_8 PF13183.1 EEA07713.1 - 9.6 6.3 7.4 2.4e+02 1.8 5.1 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain RPAP2_Rtr1 PF04181.8 EEA07714.1 - 1.2e-10 41.2 0.3 1.2e-10 41.2 0.2 2.3 3 0 0 3 3 3 1 Rtr1/RPAP2 family CENP-H PF05837.7 EEA07714.1 - 0.015 15.4 10.0 0.015 15.4 6.9 2.3 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Ldh_1_N PF00056.18 EEA07716.1 - 1.9e-34 118.5 0.5 2.9e-34 117.8 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA07716.1 - 1.4e-30 106.3 0.0 2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EEA07716.1 - 0.015 14.5 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase 3HCDH_N PF02737.13 EEA07716.1 - 0.022 14.4 0.6 0.053 13.1 0.4 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEA07716.1 - 0.071 13.5 1.2 0.25 11.8 0.9 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EEA07716.1 - 0.085 12.8 1.0 0.35 10.8 0.6 2.1 2 1 0 2 2 2 0 NADH(P)-binding K_oxygenase PF13434.1 EEA07716.1 - 0.094 11.6 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIT1_C PF12205.3 EEA07716.1 - 0.1 12.4 0.0 5 6.9 0.0 2.4 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term UDPG_MGDP_dh_N PF03721.9 EEA07716.1 - 0.24 10.7 1.7 0.81 9.0 1.0 2.1 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Keratin PF02422.11 EEA07716.1 - 9.1 6.3 7.4 33 4.5 0.1 3.3 3 1 0 4 4 4 0 Keratin Ldh_1_N PF00056.18 EEA07717.1 - 5.8e-43 146.0 0.1 3.5e-42 143.5 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA07717.1 - 2.9e-30 105.2 0.0 6.2e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 EEA07717.1 - 0.00028 20.3 0.9 0.0045 16.3 0.6 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.11 EEA07717.1 - 0.0086 15.3 2.7 0.03 13.6 0.1 2.5 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase NAD_Gly3P_dh_N PF01210.18 EEA07717.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EEA07717.1 - 0.044 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 EEA07717.1 - 0.11 12.6 0.4 0.37 10.9 0.3 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEA07717.1 - 0.38 10.1 1.6 1 8.7 1.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EEA07717.1 - 0.47 10.9 5.2 0.65 10.4 1.2 2.8 2 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent E1-E2_ATPase PF00122.15 EEA07718.1 - 4.2e-30 104.5 11.4 4.8e-24 84.6 0.2 3.3 3 1 1 4 4 4 2 E1-E2 ATPase HAD PF12710.2 EEA07718.1 - 7.7e-17 62.0 0.1 1.6e-16 61.0 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA07718.1 - 4e-12 47.0 2.7 2e-08 34.8 1.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA07718.1 - 0.00017 21.5 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF3043 PF11241.3 EEA07718.1 - 8.1 6.0 10.6 14 5.2 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) E1-E2_ATPase PF00122.15 EEA07719.1 - 2.1e-19 69.4 0.4 3.4e-19 68.7 0.2 1.4 1 1 0 1 1 1 1 E1-E2 ATPase CTP_transf_1 PF01148.15 EEA07720.1 - 1.5e-68 231.2 24.8 1.9e-68 230.9 17.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family MerC PF03203.9 EEA07720.1 - 8.1 6.8 12.5 1 9.7 1.6 3.0 2 1 1 3 3 3 0 MerC mercury resistance protein RIO1 PF01163.17 EEA07721.1 - 6.2e-45 152.8 1.8 7.9e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 EEA07721.1 - 1.4e-31 108.3 0.2 3.5e-31 107.0 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EEA07721.1 - 3e-07 30.4 0.5 0.026 14.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEA07721.1 - 0.00041 19.4 0.1 0.0039 16.2 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1409 PF07197.7 EEA07721.1 - 0.02 14.9 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF261 PF03196.8 EEA07721.1 - 0.045 13.7 1.9 0.094 12.6 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF261 Pkinase PF00069.20 EEA07722.1 - 4.7e-65 219.3 0.0 5.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07722.1 - 1.5e-30 106.1 0.0 2.2e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07722.1 - 0.00035 19.6 0.0 0.00054 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA07722.1 - 0.0097 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 EEA07723.1 - 1.5e-38 132.2 0.0 2.7e-37 128.2 0.0 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EEA07723.1 - 5.6e-07 29.1 6.3 5.6e-07 29.1 4.4 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07723.1 - 8.4e-05 22.1 10.5 8.4e-05 22.1 7.3 4.6 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA07723.1 - 0.00014 21.3 6.6 0.00014 21.3 4.6 3.6 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain Helicase_C PF00271.26 EEA07723.1 - 0.00056 19.7 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEA07723.1 - 0.00086 19.2 10.6 0.00086 19.2 7.3 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07723.1 - 0.003 17.2 8.4 0.003 17.2 5.8 4.3 3 2 0 3 3 3 1 zinc-RING finger domain zf-UDP PF14569.1 EEA07723.1 - 0.0051 16.5 0.9 0.023 14.4 0.6 2.1 1 0 0 1 1 1 1 Zinc-binding RING-finger TPR_2 PF07719.12 EEA07723.1 - 0.1 12.5 0.7 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FYDLN_acid PF09538.5 EEA07723.1 - 7.3 7.2 6.6 2.7 8.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) OHA PF14418.1 EEA07725.1 - 1.9e-27 94.5 0.2 2e-26 91.3 0.1 2.9 2 0 0 2 2 2 1 OST-HTH Associated domain PAT1 PF09770.4 EEA07726.1 - 0.14 10.3 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_18 PF13238.1 EEA07727.1 - 9.6e-09 35.6 2.2 1.6e-08 34.9 0.6 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA07727.1 - 1.4e-08 35.6 1.0 8.6e-08 33.0 0.1 2.6 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA07727.1 - 1.8e-07 31.1 0.1 5.3e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA07727.1 - 2.8e-06 26.5 0.0 2.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EEA07727.1 - 6.6e-06 25.6 0.3 0.0067 15.8 0.1 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_23 PF13476.1 EEA07727.1 - 0.00038 20.8 0.7 0.0006 20.1 0.5 1.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA07727.1 - 0.00038 19.4 0.8 0.016 14.1 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein APS_kinase PF01583.15 EEA07727.1 - 0.00038 20.1 0.0 0.00071 19.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EEA07727.1 - 0.0016 17.9 1.4 0.003 17.1 0.4 1.9 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EEA07727.1 - 0.004 17.1 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.7 EEA07727.1 - 0.012 15.2 0.1 0.033 13.8 0.1 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 EEA07727.1 - 0.013 15.3 3.9 1.5 8.7 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase SMC_N PF02463.14 EEA07727.1 - 0.014 14.6 0.1 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EEA07727.1 - 0.016 15.1 0.1 0.048 13.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 EEA07727.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 EEA07727.1 - 0.033 13.5 0.4 0.1 11.9 0.3 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DDE_Tnp_IS1595 PF12762.2 EEA07727.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 ISXO2-like transposase domain SRP54 PF00448.17 EEA07727.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 EEA07727.1 - 0.096 12.3 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA07727.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EEA07727.1 - 0.15 11.4 0.3 2.6 7.3 1.3 2.3 1 1 1 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EEA07727.1 - 0.25 11.6 2.1 0.76 10.0 1.5 2.0 1 1 0 1 1 1 0 ABC transporter RRM_1 PF00076.17 EEA07728.1 - 3.5e-07 29.7 0.0 2e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07728.1 - 8.1e-07 28.9 0.0 2.3e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF947 PF06102.7 EEA07728.1 - 0.041 13.7 3.4 0.047 13.5 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF947) LPP20 PF02169.11 EEA07728.1 - 7.3 6.7 8.7 6.4 6.9 2.8 2.8 2 1 0 2 2 2 0 LPP20 lipoprotein Abhydrolase_5 PF12695.2 EEA07729.1 - 3.9e-17 62.3 0.0 6.5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA07729.1 - 5.9e-12 45.9 0.0 1.2e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 EEA07729.1 - 3e-10 39.1 0.2 2.5e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.13 EEA07729.1 - 2.8e-08 33.5 0.2 5.4e-06 26.0 0.1 2.7 2 1 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 EEA07729.1 - 8.9e-06 25.2 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EEA07729.1 - 1.8e-05 24.3 1.6 0.0049 16.4 0.1 2.8 2 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA07729.1 - 0.00045 19.5 0.1 0.0073 15.5 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EEA07729.1 - 0.003 17.2 0.0 0.0081 15.8 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Rcd1 PF04078.8 EEA07729.1 - 0.018 13.8 0.1 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like HSP70 PF00012.15 EEA07730.1 - 6.1e-261 866.6 12.2 7e-261 866.4 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA07730.1 - 9.1e-20 70.4 1.7 1e-18 67.0 0.7 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEA07730.1 - 0.00066 18.8 1.9 0.15 11.1 0.1 3.4 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DUF1894 PF08979.6 EEA07730.1 - 0.036 14.1 0.0 0.37 10.8 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) Ribonuc_L-PSP PF01042.16 EEA07730.1 - 0.08 12.6 0.5 0.64 9.7 0.0 2.7 3 0 0 3 3 3 0 Endoribonuclease L-PSP FtsA PF14450.1 EEA07730.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.9 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.6 EEA07730.1 - 0.6 8.9 5.1 0.18 10.7 0.1 2.3 2 1 0 2 2 2 0 StbA protein Effector_1 PF04518.7 EEA07730.1 - 0.76 8.7 6.2 0.99 8.3 0.2 2.3 2 0 0 2 2 2 0 Effector from type III secretion system ATG16 PF08614.6 EEA07731.1 - 6.7e-06 26.0 13.0 1.5e-05 24.9 9.0 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EEA07731.1 - 0.00035 18.0 5.9 0.00041 17.8 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.6 EEA07731.1 - 0.0024 16.5 11.1 0.0031 16.2 7.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Med9 PF07544.8 EEA07731.1 - 0.0027 17.4 5.8 0.0027 17.4 4.0 2.1 2 1 0 2 2 1 1 RNA polymerase II transcription mediator complex subunit 9 Myosin_tail_1 PF01576.14 EEA07731.1 - 0.0028 15.4 9.2 0.0035 15.1 6.4 1.0 1 0 0 1 1 1 1 Myosin tail APG6 PF04111.7 EEA07731.1 - 0.006 15.6 8.2 0.0071 15.4 5.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EEA07731.1 - 0.011 14.9 1.0 0.012 14.7 0.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EEA07731.1 - 0.03 13.2 5.5 0.034 13.0 3.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 THOC7 PF05615.8 EEA07731.1 - 0.037 14.2 10.5 1.4 9.2 3.7 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Baculo_PEP_C PF04513.7 EEA07731.1 - 0.037 13.8 3.4 0.052 13.3 2.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EEA07731.1 - 0.044 13.6 11.4 0.29 10.9 4.7 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 EEA07731.1 - 0.048 13.6 9.7 0.096 12.6 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CDO_I PF05995.7 EEA07731.1 - 0.054 12.6 0.8 0.1 11.7 0.6 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I Laminin_II PF06009.7 EEA07731.1 - 0.12 12.1 7.7 0.19 11.4 5.3 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4140 PF13600.1 EEA07731.1 - 0.13 12.6 2.6 2.2 8.7 0.7 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 EEA07731.1 - 0.14 10.5 9.2 0.17 10.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF745 PF05335.8 EEA07731.1 - 0.14 11.6 2.9 0.17 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) WD-3 PF09765.4 EEA07731.1 - 0.17 11.1 7.2 0.2 10.9 4.8 1.2 1 1 0 1 1 1 0 WD-repeat region L27_1 PF09058.5 EEA07731.1 - 0.18 11.7 1.6 2 8.3 0.0 2.6 2 1 1 3 3 3 0 L27_1 DUF1664 PF07889.7 EEA07731.1 - 0.19 11.5 5.3 0.29 10.9 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF641 PF04859.7 EEA07731.1 - 0.2 11.3 6.5 0.49 10.1 4.5 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-Q PF13094.1 EEA07731.1 - 0.22 11.5 10.3 0.78 9.7 4.5 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 EEA07731.1 - 0.23 11.8 8.1 0.34 11.3 2.3 2.3 1 1 1 2 2 2 0 SlyX Cep57_CLD_2 PF14197.1 EEA07731.1 - 0.23 11.4 6.8 0.47 10.4 4.3 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Sec2p PF06428.6 EEA07731.1 - 0.26 11.1 12.1 0.13 12.0 4.0 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FlxA PF14282.1 EEA07731.1 - 0.3 11.0 15.8 0.81 9.6 7.7 2.8 1 1 1 2 2 2 0 FlxA-like protein ADIP PF11559.3 EEA07731.1 - 0.35 10.7 13.2 0.61 9.9 7.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EEA07731.1 - 0.55 10.0 15.3 25 4.7 10.3 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEA07731.1 - 0.6 9.6 12.3 0.97 9.0 8.5 1.6 1 1 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EEA07731.1 - 0.63 9.2 9.0 0.55 9.4 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4404 PF14357.1 EEA07731.1 - 0.74 10.2 4.8 1.7 9.1 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) XRCC4 PF06632.7 EEA07731.1 - 0.79 8.5 9.4 0.31 9.8 1.7 2.0 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF948 PF06103.6 EEA07731.1 - 0.8 9.5 3.7 2 8.2 2.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EEA07731.1 - 1 7.1 6.8 1.2 6.8 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EEA07731.1 - 1.1 8.9 12.4 12 5.6 0.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fez1 PF06818.10 EEA07731.1 - 1.2 9.1 10.7 3.1 7.7 0.1 2.2 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.5 EEA07731.1 - 1.2 9.2 9.0 1.9 8.5 6.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family cwf21 PF08312.7 EEA07731.1 - 1.5 8.7 7.1 1 9.2 1.3 2.7 3 1 0 3 3 2 0 cwf21 domain Syntaxin PF00804.20 EEA07731.1 - 1.7 8.8 12.7 0.79 9.9 7.2 1.6 2 0 0 2 2 1 0 Syntaxin DUF2802 PF10975.3 EEA07731.1 - 1.9 8.2 6.3 6.1 6.6 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF4559 PF15112.1 EEA07731.1 - 2.7 7.0 12.3 3.7 6.6 8.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF972 PF06156.8 EEA07731.1 - 3.3 8.1 10.7 2.5 8.4 2.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EEA07731.1 - 3.5 7.5 7.1 1.4 8.7 2.2 2.5 2 1 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 EEA07731.1 - 4.2 6.9 11.1 1.2 8.6 3.9 2.4 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EEA07731.1 - 4.4 7.6 7.1 6.7 7.0 2.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 EEA07731.1 - 4.5 7.6 16.9 0.66 10.3 3.4 3.2 2 1 2 4 4 3 0 Protein of unknown function (DUF904) Prefoldin_2 PF01920.15 EEA07731.1 - 4.6 7.0 15.9 0.33 10.7 3.9 2.8 2 1 1 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.16 EEA07731.1 - 6 6.8 12.1 0.24 11.3 3.3 2.3 2 1 0 3 3 2 0 bZIP transcription factor AAA_23 PF13476.1 EEA07731.1 - 6.4 7.0 18.0 7.7 6.7 12.5 1.1 1 0 0 1 1 1 0 AAA domain DUF2672 PF10878.3 EEA07732.1 - 0.0039 16.8 0.1 0.014 15.1 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2672) GRASP55_65 PF04495.9 EEA07733.1 - 4.4e-36 123.9 0.1 3.2e-28 98.4 0.0 2.7 2 1 1 3 3 3 2 GRASP55/65 PDZ-like domain EMP70 PF02990.11 EEA07734.1 - 2.5e-97 326.5 26.8 4.5e-97 325.6 18.6 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_L18ae PF01775.12 EEA07735.1 - 1.5e-48 163.7 0.7 1.9e-48 163.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain GLE1 PF07817.8 EEA07736.1 - 1.8e-20 72.9 3.0 1.8e-20 72.9 2.1 3.2 2 1 0 2 2 2 1 GLE1-like protein Bud13 PF09736.4 EEA07736.1 - 9 6.5 17.2 15 5.7 11.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex LCCL PF03815.14 EEA07737.1 - 5.5e-19 67.9 0.0 5.5e-19 67.9 0.0 2.8 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.20 EEA07737.1 - 7.7e-14 51.6 1.0 2.8e-09 36.8 0.1 2.8 3 0 0 3 3 3 2 F5/8 type C domain Ricin_B_lectin PF00652.17 EEA07737.1 - 0.00011 22.2 0.0 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Rad21_Rec8_N PF04825.8 EEA07738.1 - 2.1e-21 75.9 0.1 5.4e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEA07738.1 - 3.8e-07 29.1 0.0 8.5e-07 28.0 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EEA07738.1 - 4.5e-05 23.1 0.3 0.00016 21.3 0.0 2.2 2 1 0 2 2 2 1 ScpA/B protein Pkinase PF00069.20 EEA07739.1 - 1.2e-62 211.4 0.0 1.5e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07739.1 - 8.5e-31 106.9 0.0 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07739.1 - 0.011 14.7 0.0 0.047 12.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Amino_oxidase PF01593.19 EEA07740.1 - 1.3e-25 90.4 0.0 1.1e-22 80.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA07740.1 - 2.9e-05 24.0 0.0 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA07740.1 - 3.3e-05 22.9 0.5 4.7e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA07740.1 - 3.5e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA07740.1 - 6.6e-05 21.5 0.1 0.00011 20.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EEA07740.1 - 7.8e-05 21.7 0.0 0.00035 19.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA07740.1 - 0.00021 20.4 0.1 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EEA07740.1 - 0.00071 18.5 1.6 0.002 17.0 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EEA07740.1 - 0.00098 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA07740.1 - 0.0012 17.9 0.1 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EEA07740.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EEA07740.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EEA07740.1 - 0.054 13.9 1.6 0.065 13.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEA07740.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EEA07740.1 - 0.16 11.9 0.2 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain VIT1 PF01988.14 EEA07741.1 - 2.2e-54 184.2 0.4 2.7e-54 183.9 0.3 1.1 1 0 0 1 1 1 1 VIT family COesterase PF00135.23 EEA07741.1 - 0.099 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF3735 PF12537.3 EEA07741.1 - 1.2 9.2 3.7 28 4.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) DUF1253 PF06862.7 EEA07742.1 - 3.7e-125 417.8 0.1 5.5e-125 417.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) dTMP_synthase PF02593.9 EEA07742.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate synthase KSR1-SAM PF13543.1 EEA07743.1 - 0.00038 20.2 1.3 0.00094 18.9 0.9 1.7 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 HrcA_DNA-bdg PF03444.10 EEA07743.1 - 0.29 10.5 3.4 5.7 6.4 0.4 2.7 2 1 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding RNase_PH PF01138.16 EEA07744.1 - 1.2e-16 61.2 0.4 2e-16 60.5 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Ras PF00071.17 EEA07745.1 - 2e-50 170.3 0.0 2.4e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07745.1 - 2e-16 60.5 0.0 4.6e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA07745.1 - 5e-12 45.4 0.0 6.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EEA07745.1 - 0.0012 18.9 0.2 0.01 15.9 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EEA07745.1 - 0.005 16.0 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA07745.1 - 0.012 15.6 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA07745.1 - 0.022 14.1 0.6 0.48 9.8 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEA07745.1 - 0.03 14.4 0.2 0.17 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEA07745.1 - 0.031 13.1 0.0 0.097 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 EEA07745.1 - 0.042 12.5 0.0 2.2 6.8 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.22 EEA07745.1 - 0.043 14.1 0.2 0.19 12.0 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Pox_A32 PF04665.7 EEA07745.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 EEA07745.1 - 0.13 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FKBP_C PF00254.23 EEA07746.1 - 1.1e-24 86.2 0.0 2.3e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OTU PF02338.14 EEA07747.1 - 0.00019 22.0 0.1 0.0092 16.5 0.0 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease TFR_dimer PF04253.10 EEA07747.1 - 0.1 12.2 2.9 0.1 12.1 0.8 1.9 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Dynamitin PF04912.9 EEA07748.1 - 1.3e-23 83.4 20.3 1.3e-23 83.4 14.1 1.5 1 1 0 1 1 1 1 Dynamitin DUF2443 PF10398.4 EEA07748.1 - 0.011 15.4 8.5 0.14 12.0 0.3 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) GM_CSF PF01109.12 EEA07748.1 - 0.025 14.5 0.4 0.24 11.3 0.0 2.7 2 2 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor E2R135 PF11570.3 EEA07748.1 - 1.4 9.0 4.7 5.7 7.0 0.1 3.6 3 1 1 4 4 4 0 Coiled-coil receptor-binding R-domain of colicin E2 WD40 PF00400.27 EEA07750.1 - 0.00042 20.0 8.4 0.0066 16.3 0.9 4.9 6 1 0 6 6 6 1 WD domain, G-beta repeat CPSF_A PF03178.10 EEA07750.1 - 0.043 12.9 0.8 0.79 8.7 0.2 3.2 1 1 0 2 2 2 0 CPSF A subunit region SUKH_6 PF14568.1 EEA07750.1 - 2.9 8.3 9.9 4.4 7.8 1.5 3.6 2 2 2 4 4 4 0 SMI1-KNR4 cell-wall Methyltransf_4 PF02390.12 EEA07751.1 - 5.2e-50 169.2 0.0 6.3e-50 168.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEA07751.1 - 3.3e-05 24.4 0.0 5.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA07751.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EEA07751.1 - 0.0094 15.2 0.0 0.063 12.5 0.0 1.9 1 1 1 2 2 2 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EEA07751.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA07751.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EEA07751.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 EEA07751.1 - 0.015 15.7 0.0 0.047 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07751.1 - 0.019 15.2 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEA07751.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EEA07751.1 - 0.064 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1021 PF06257.6 EEA07751.1 - 0.12 12.0 0.1 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) SprT-like PF10263.4 EEA07753.1 - 3.3e-26 91.8 0.9 8.8e-26 90.4 0.6 1.7 1 0 0 1 1 1 1 SprT-like family Ribosomal_S11 PF00411.14 EEA07754.1 - 1.7e-40 137.6 0.5 2.2e-40 137.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 EEA07754.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) cNMP_binding PF00027.24 EEA07755.1 - 1.9e-44 149.3 0.0 1.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 EEA07755.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 Cupin domain BNR PF02012.15 EEA07756.1 - 0.0013 18.2 13.6 0.8 9.7 0.1 6.7 9 0 0 9 9 9 3 BNR/Asp-box repeat UCR_UQCRX_QCR9 PF05365.7 EEA07756.1 - 0.85 9.2 7.8 0.17 11.5 0.1 3.8 5 0 0 5 5 5 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-C3HC4_3 PF13920.1 EEA07757.1 - 1.7e-06 27.6 10.3 1.7e-06 27.6 7.1 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07757.1 - 1.1e-05 25.2 14.1 1.1e-05 25.2 9.8 3.8 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EEA07757.1 - 1.6e-05 24.4 13.5 1.6e-05 24.4 9.4 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA07757.1 - 1.8e-05 24.5 12.4 1.8e-05 24.5 8.6 5.0 5 2 2 7 7 7 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEA07757.1 - 3.8e-05 23.6 14.8 3.8e-05 23.6 10.2 4.4 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07757.1 - 4e-05 23.2 12.2 4e-05 23.2 8.5 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA07757.1 - 0.0013 18.3 5.2 0.0013 18.3 3.6 4.1 5 0 0 5 5 5 1 RING-type zinc-finger Rubredoxin PF00301.15 EEA07757.1 - 0.086 12.7 13.9 0.44 10.4 0.0 4.9 5 0 0 5 5 5 0 Rubredoxin U-box PF04564.10 EEA07757.1 - 0.44 10.5 2.6 0.51 10.3 0.1 2.4 3 0 0 3 3 3 0 U-box domain Sulfate_transp PF00916.15 EEA07758.1 - 5.6e-32 110.8 21.2 1.5e-19 70.1 0.5 3.5 3 1 1 4 4 4 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEA07758.1 - 2e-18 65.8 3.5 7.1e-18 64.0 2.5 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEA07758.1 - 4.3e-09 35.8 2.8 4.3e-08 32.5 1.9 2.5 1 1 0 1 1 1 1 STAS domain DUF4227 PF14004.1 EEA07758.1 - 0.11 12.2 0.9 0.36 10.7 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) ATP_bind_1 PF03029.12 EEA07759.1 - 1e-70 238.0 0.0 1.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EEA07759.1 - 4.1e-05 23.6 0.4 5.5e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA07759.1 - 0.00022 22.0 0.9 0.00058 20.6 0.4 1.8 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEA07759.1 - 0.00029 20.7 0.5 0.00089 19.1 0.4 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EEA07759.1 - 0.0022 17.8 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA07759.1 - 0.0034 16.8 0.0 0.0082 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 EEA07759.1 - 0.0049 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EEA07759.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA07759.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA07759.1 - 0.0073 16.3 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA07759.1 - 0.0073 16.4 0.1 0.043 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA07759.1 - 0.0083 15.3 0.0 0.028 13.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEA07759.1 - 0.011 16.0 1.0 0.058 13.7 0.7 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA07759.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.13 EEA07759.1 - 0.021 13.8 0.1 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 EEA07759.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EEA07759.1 - 0.028 13.8 0.0 0.058 12.7 0.0 1.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EEA07759.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EEA07759.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EEA07759.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEA07759.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEA07759.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EEA07759.1 - 0.24 11.0 1.1 0.98 9.1 0.0 2.3 3 0 0 3 3 3 0 NTPase zf-C3HC4_3 PF13920.1 EEA07760.1 - 8.8e-11 41.3 4.2 8.8e-11 41.3 2.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07760.1 - 8e-07 28.9 6.3 8e-07 28.9 4.4 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07760.1 - 0.012 15.3 6.1 0.012 15.3 4.3 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 EEA07760.1 - 0.013 15.3 5.6 0.013 15.3 3.9 2.7 3 0 0 3 3 3 0 Ring finger domain DUF1514 PF07438.6 EEA07760.1 - 0.046 13.6 5.8 0.053 13.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Hat1_N PF10394.4 EEA07761.1 - 3.8e-15 56.3 4.8 3.8e-15 56.3 3.3 2.2 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EEA07761.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA07761.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA07761.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 EEA07761.1 - 0.065 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.16 EEA07762.1 - 6e-12 45.0 1.6 6e-12 45.0 1.1 2.1 1 1 1 2 2 2 1 Synaptobrevin DUF2207 PF09972.4 EEA07762.1 - 0.0043 15.6 0.9 0.0047 15.5 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.1 EEA07762.1 - 0.0058 16.6 1.9 0.0087 16.0 1.3 1.3 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Sec20 PF03908.8 EEA07762.1 - 0.016 14.8 4.6 0.016 14.8 3.2 2.1 2 1 0 2 2 2 0 Sec20 Pex24p PF06398.6 EEA07762.1 - 0.04 12.7 0.5 0.045 12.5 0.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Rifin_STEVOR PF02009.11 EEA07762.1 - 0.053 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Presenilin PF01080.12 EEA07762.1 - 0.083 11.7 2.5 0.092 11.5 1.7 1.1 1 0 0 1 1 1 0 Presenilin Halogen_Hydrol PF10112.4 EEA07762.1 - 0.1 11.9 5.5 0.28 10.5 1.1 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Cir_Bir_Yir PF06022.6 EEA07762.1 - 2.5 7.2 10.2 35 3.4 7.0 2.0 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir PspB PF06667.7 EEA07762.1 - 4.6 7.2 6.7 38 4.3 0.0 2.3 2 0 0 2 2 2 0 Phage shock protein B Ank_2 PF12796.2 EEA07764.1 - 4.5e-50 167.9 9.1 3.3e-21 75.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA07764.1 - 6.2e-31 104.6 7.1 7.1e-08 31.8 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EEA07764.1 - 2.4e-30 104.3 7.4 7.9e-15 54.9 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA07764.1 - 4e-26 88.4 3.4 2.2e-07 30.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EEA07764.1 - 2.6e-22 78.3 2.7 9.2e-13 47.9 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Gly-zipper_OmpA PF13436.1 EEA07767.1 - 0.0016 18.0 0.2 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EEA07767.1 - 0.0026 17.3 6.1 0.004 16.7 4.2 1.2 1 0 0 1 1 1 1 Glycine zipper Romo1 PF10247.4 EEA07767.1 - 0.014 15.5 0.1 0.014 15.5 0.0 2.2 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Rick_17kDa_Anti PF05433.10 EEA07767.1 - 0.23 11.1 9.8 0.15 11.7 0.3 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 EEA07767.1 - 1.4 9.0 10.1 2.5 8.2 7.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF726 PF05277.7 EEA07768.1 - 9.5e-86 287.7 1.9 1.4e-85 287.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.17 EEA07768.1 - 0.001 18.8 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Cutinase Lipase_3 PF01764.20 EEA07768.1 - 0.085 12.4 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EEA07768.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 EEA07768.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_1 PF00667.15 EEA07769.1 - 2.4e-28 99.1 0.0 2.3e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Flavodoxin_1 PF00258.20 EEA07769.1 - 2.5e-15 56.7 0.0 5.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.6 EEA07769.1 - 0.04 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 NrdI Flavodoxin like Bromodomain PF00439.20 EEA07770.1 - 2.7e-30 104.1 5.1 2.6e-18 65.7 0.2 2.7 2 0 0 2 2 2 2 Bromodomain RCC1 PF00415.13 EEA07771.1 - 1.8e-41 140.0 0.0 1.2e-07 31.7 0.0 9.5 8 3 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA07771.1 - 1.9e-20 71.9 49.0 5.6e-08 32.2 0.1 8.1 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat zf-C3HC4_3 PF13920.1 EEA07772.1 - 7.5e-13 47.9 8.8 1.4e-12 47.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07772.1 - 1.5e-05 24.9 13.6 1.5e-05 24.9 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07772.1 - 0.0017 18.1 13.2 0.0017 18.1 9.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA07772.1 - 0.0025 17.4 13.3 0.0053 16.3 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EEA07772.1 - 0.0052 16.2 4.6 0.011 15.2 3.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1644 PF07800.7 EEA07772.1 - 1.4 8.7 7.3 11 5.8 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DUF1825 PF08855.5 EEA07773.1 - 0.019 14.9 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) HD_2 PF12917.2 EEA07773.1 - 0.023 14.4 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Cut8_M PF14483.1 EEA07773.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cut8 dimerisation domain PRD PF00874.15 EEA07773.1 - 0.11 12.6 0.9 0.34 11.0 0.6 1.9 2 1 0 2 2 2 0 PRD domain ABC_tran PF00005.22 EEA07774.1 - 1.3e-15 57.9 0.0 1.3e-08 35.2 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_17 PF13207.1 EEA07774.1 - 0.00015 22.5 0.3 0.001 19.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EEA07774.1 - 0.00024 21.3 0.0 0.001 19.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEA07774.1 - 0.0023 17.6 0.1 0.0088 15.7 0.0 2.0 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EEA07774.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EEA07774.1 - 0.024 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA07774.1 - 0.029 14.5 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEA07774.1 - 0.058 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EEA07774.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEA07774.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EEA07775.1 - 7.4e-19 68.4 0.0 2.4e-09 37.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Arch_ATPase PF01637.13 EEA07775.1 - 0.00017 21.3 0.1 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase AAA_18 PF13238.1 EEA07775.1 - 0.0013 19.0 0.7 0.12 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EEA07775.1 - 0.0075 16.2 0.2 10 6.1 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.14 EEA07775.1 - 0.013 14.7 2.8 2.5 7.2 0.0 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 EEA07775.1 - 0.052 14.0 2.5 9.4 6.7 0.5 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 EEA07775.1 - 0.071 13.9 0.0 7.1 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA07775.1 - 0.12 12.1 0.2 23 4.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EEA07775.1 - 0.26 11.2 0.6 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EEA07776.1 - 2.4e-17 63.4 0.0 4.2e-08 33.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EEA07776.1 - 5.7e-05 22.6 0.1 0.024 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA07776.1 - 9.1e-05 21.9 0.9 0.56 9.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EEA07776.1 - 9.8e-05 22.8 0.9 0.88 10.0 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EEA07776.1 - 0.00011 21.8 0.2 0.094 12.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EEA07776.1 - 0.00052 20.3 7.9 0.0041 17.4 0.1 3.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEA07776.1 - 0.00067 18.9 0.0 0.29 10.3 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EEA07776.1 - 0.0012 18.9 0.2 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA07776.1 - 0.0029 17.5 2.1 1.4 8.8 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EEA07776.1 - 0.0034 17.6 0.3 1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEA07776.1 - 0.0044 16.7 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEA07776.1 - 0.014 14.5 0.4 3.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EEA07776.1 - 0.017 14.8 0.2 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EEA07776.1 - 0.017 15.1 0.6 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EEA07776.1 - 0.023 15.4 0.3 0.21 12.4 0.0 2.8 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EEA07776.1 - 0.71 9.4 0.0 1.2 8.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA07776.1 - 0.9 8.9 2.8 21 4.4 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EEA07776.1 - 9.4 6.0 8.7 4.4 7.0 0.4 3.2 4 0 0 4 4 3 0 Dynamin family Pyrophosphatase PF00719.14 EEA07777.1 - 7.4e-47 158.6 0.0 1.2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase SK_channel PF03530.9 EEA07778.1 - 0.047 13.5 0.2 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated SK potassium channel DUF4199 PF13858.1 EEA07778.1 - 0.26 11.2 1.9 0.23 11.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) N2227 PF07942.7 EEA07779.1 - 2.1e-89 299.1 0.0 6.7e-89 297.4 0.0 1.8 2 0 0 2 2 2 1 N2227-like protein SieB PF14163.1 EEA07779.1 - 0.13 11.8 0.9 0.96 9.0 0.0 2.6 3 0 0 3 3 3 0 Superinfection exclusion protein B TAP42 PF04177.7 EEA07780.1 - 2.4e-50 171.3 8.6 2.9e-50 171.1 6.0 1.0 1 0 0 1 1 1 1 TAP42-like family Reticulon PF02453.12 EEA07783.1 - 0.063 12.8 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Reticulon V_ATPase_I PF01496.14 EEA07784.1 - 4e-162 540.8 17.5 4.3e-161 537.4 12.1 1.9 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF663 PF04950.7 EEA07785.1 - 4.8e-71 239.1 1.0 4.8e-71 239.1 0.7 3.4 4 0 0 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEA07785.1 - 8.3e-27 92.5 0.0 2.9e-26 90.7 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EEA07785.1 - 1.7e-07 30.9 0.1 3.1e-06 26.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEA07785.1 - 9.9e-05 23.1 0.0 9.9e-05 23.1 0.0 3.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEA07785.1 - 0.00034 20.7 0.0 0.00095 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA07785.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 EEA07785.1 - 0.00053 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA07785.1 - 0.00072 19.4 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA07785.1 - 0.001 18.6 0.0 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain PduV-EutP PF10662.4 EEA07785.1 - 0.0011 18.4 0.0 0.0061 16.0 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EEA07785.1 - 0.0012 18.7 0.2 0.0067 16.3 0.1 2.4 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EEA07785.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEA07785.1 - 0.0027 18.0 0.0 0.0027 18.0 0.0 3.1 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 EEA07785.1 - 0.0033 17.1 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EEA07785.1 - 0.0038 16.6 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEA07785.1 - 0.0059 16.3 0.1 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEA07785.1 - 0.0059 16.5 1.6 0.023 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EEA07785.1 - 0.0098 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EEA07785.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEA07785.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EEA07785.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EEA07785.1 - 0.014 15.6 3.0 0.026 14.7 0.1 3.0 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 EEA07785.1 - 0.017 15.5 0.0 0.093 13.2 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 EEA07785.1 - 0.025 14.7 0.0 0.091 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EEA07785.1 - 0.029 13.5 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EEA07785.1 - 0.053 13.0 0.3 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EEA07785.1 - 0.06 12.8 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEA07785.1 - 0.08 11.7 0.0 0.2 10.4 0.0 1.6 1 0 0 1 1 1 0 ArgK protein HrpB4 PF09502.5 EEA07785.1 - 0.42 9.7 0.0 0.87 8.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) DNA_primase_S PF01896.14 EEA07786.1 - 1.7e-47 160.8 2.4 2.7e-47 160.2 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit PhoU_div PF01865.11 EEA07787.1 - 0.017 14.3 1.2 0.024 13.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 ASD2 PF08687.6 EEA07787.1 - 0.042 13.1 0.3 0.046 13.0 0.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 AAA_23 PF13476.1 EEA07787.1 - 0.081 13.2 6.6 0.091 13.0 4.5 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 EEA07787.1 - 0.18 11.9 2.6 0.25 11.5 1.8 1.2 1 0 0 1 1 1 0 Syntaxin Prenyltransf PF01255.14 EEA07788.1 - 3.5e-53 180.0 0.9 4.6e-53 179.6 0.6 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase FAM217 PF15344.1 EEA07789.1 - 0.054 13.0 0.1 0.059 12.9 0.1 1.0 1 0 0 1 1 1 0 FAM217 family Rap1_C PF11626.3 EEA07789.1 - 0.057 13.3 0.1 0.07 13.0 0.1 1.1 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain E1-N PF14463.1 EEA07789.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 E1 N-terminal domain Brix PF04427.13 EEA07790.1 - 5.7e-37 127.2 0.2 8.7e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Brix domain Abhydrolase_5 PF12695.2 EEA07791.1 - 6.7e-22 77.8 0.0 9.6e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA07791.1 - 1e-09 38.6 0.0 0.00032 20.6 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA07791.1 - 3.8e-09 36.4 0.1 0.00022 20.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA07791.1 - 1.4e-05 24.6 0.2 0.00019 20.9 0.1 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EEA07791.1 - 0.00054 19.4 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EEA07791.1 - 0.00068 18.9 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.5 EEA07791.1 - 0.0038 16.1 0.1 0.007 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.3 EEA07791.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase DLH PF01738.13 EEA07791.1 - 0.091 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF818 PF05677.7 EEA07791.1 - 0.099 11.3 0.5 0.22 10.2 0.1 1.7 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) RabGAP-TBC PF00566.13 EEA07793.1 - 2.1e-33 115.6 12.1 2.1e-33 115.6 8.4 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box-like PF12937.2 EEA07793.1 - 0.0086 15.7 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like RFC1 PF08519.7 EEA07793.1 - 0.022 14.5 1.7 0.062 13.0 1.2 1.8 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain F-box PF00646.28 EEA07793.1 - 0.034 13.7 1.6 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 F-box domain WD40 PF00400.27 EEA07794.1 - 8.9e-25 85.6 13.0 3.3e-06 26.7 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA07794.1 - 1.7e-20 72.6 2.1 1.2e-18 66.6 1.5 2.5 1 1 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mog1 PF04603.7 EEA07795.1 - 1.2e-23 83.5 0.1 1.9e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein zf-RING_2 PF13639.1 EEA07796.1 - 5.6e-14 51.6 6.4 5.6e-14 51.6 4.4 2.0 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA07796.1 - 3.2e-08 33.5 2.9 3.2e-08 33.5 2.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEA07796.1 - 6.4e-07 29.2 6.7 6.4e-07 29.2 4.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07796.1 - 7.7e-07 28.6 4.8 1.9e-06 27.4 3.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07796.1 - 3.7e-06 26.4 6.3 1.1e-05 24.9 4.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07796.1 - 8.3e-06 25.4 4.8 2.7e-05 23.8 3.3 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA07796.1 - 0.00016 21.4 0.7 0.00039 20.1 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CDC48_2 PF02933.12 EEA07796.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 zf-C3HC4_4 PF15227.1 EEA07796.1 - 0.046 13.6 5.8 0.17 11.7 4.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEA07796.1 - 0.2 11.6 5.1 0.69 9.9 3.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEA07796.1 - 0.21 11.3 6.7 0.53 10.0 4.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EEA07796.1 - 0.28 10.9 3.6 0.23 11.2 0.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EEA07796.1 - 0.35 10.9 7.2 1 9.4 5.0 1.8 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EEA07796.1 - 0.63 9.5 5.4 1.7 8.2 3.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger PHD PF00628.24 EEA07796.1 - 2.6 7.8 12.5 0.29 10.8 3.6 2.8 3 0 0 3 3 3 0 PHD-finger RNA_pol_Rbc25 PF08292.7 EEA07797.1 - 4e-28 98.0 2.4 8.2e-27 93.8 1.6 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EEA07797.1 - 1.4e-11 44.3 0.1 2.4e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Tim17 PF02466.14 EEA07798.1 - 3.3e-21 75.6 4.7 4.2e-21 75.3 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HHH_4 PF14490.1 EEA07798.1 - 0.0039 16.9 0.2 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix containing domain Rotamase_3 PF13616.1 EEA07798.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain COPI_assoc PF08507.5 EEA07799.1 - 2.1e-07 30.6 5.2 2.9e-07 30.2 3.6 1.1 1 0 0 1 1 1 1 COPI associated protein Prenyltrans PF00432.16 EEA07800.1 - 4.1e-35 119.0 13.6 1.2e-09 37.6 0.8 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA07800.1 - 3.7e-21 75.6 0.0 1.2e-13 51.4 0.0 3.3 1 1 1 3 3 3 3 Prenyltransferase-like DUF2093 PF09866.4 EEA07800.1 - 0.01 14.9 5.7 0.023 13.8 1.5 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) HECA PF15353.1 EEA07800.1 - 0.3 10.8 1.5 0.47 10.1 0.3 1.8 2 0 0 2 2 2 0 Headcase protein family homologue Thg1 PF04446.7 EEA07801.1 - 1.3e-47 160.7 0.2 2.3e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EEA07801.1 - 4.2e-43 145.8 4.7 3.1e-42 143.0 3.3 2.0 1 1 0 1 1 1 1 Thg1 C terminal domain Utp14 PF04615.8 EEA07802.1 - 2.2e-48 165.0 46.9 1.3e-24 86.4 30.9 2.2 1 1 1 2 2 2 2 Utp14 protein CaKB PF03185.10 EEA07803.1 - 0.031 13.6 0.1 0.083 12.2 0.1 1.7 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DMPK_coil PF08826.5 EEA07803.1 - 2.6 8.0 8.9 0.72 9.7 0.9 2.8 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF3692 PF12469.3 EEA07804.1 - 0.029 14.6 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein FAM163 PF15069.1 EEA07805.1 - 0.016 15.7 0.3 0.029 14.9 0.2 1.4 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.1 EEA07805.1 - 0.082 13.3 0.2 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TauE PF01925.14 EEA07806.1 - 1.8e-19 70.1 27.6 2.9e-09 36.7 6.8 3.1 2 1 1 3 3 3 3 Sulfite exporter TauE/SafE DUF2244 PF10003.4 EEA07806.1 - 0.012 15.0 0.1 0.012 15.0 0.0 3.6 4 2 1 5 5 5 0 Integral membrane protein (DUF2244) PuR_N PF09182.5 EEA07806.1 - 0.074 12.6 5.2 0.54 9.9 0.1 3.0 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal PK PF00224.16 EEA07807.1 - 4.2e-136 453.1 5.2 2.6e-135 450.5 1.6 2.0 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 EEA07807.1 - 1.7e-30 105.0 2.0 5.1e-30 103.4 1.2 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain WD40 PF00400.27 EEA07808.1 - 6.6e-06 25.8 0.5 6.6e-06 25.8 0.3 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Pec_lyase_C PF00544.14 EEA07808.1 - 0.039 13.4 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Pectate lyase Nup160 PF11715.3 EEA07808.1 - 0.07 11.2 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PhnJ PF06007.6 EEA07808.1 - 0.081 11.6 0.0 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnJ Ras PF00071.17 EEA07809.1 - 2.2e-59 199.4 0.2 2.6e-59 199.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07809.1 - 2.2e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA07809.1 - 2e-12 46.7 0.0 2.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA07809.1 - 0.00035 20.4 0.0 0.00052 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA07809.1 - 0.003 17.0 0.0 0.035 13.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA07809.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EEA07809.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain PWWP PF00855.12 EEA07810.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 PWWP domain DUF2392 PF10288.4 EEA07811.1 - 0.0039 17.4 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 EEA07811.1 - 0.012 15.3 8.6 0.029 14.2 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF2318 PF10080.4 EEA07811.1 - 2.9 7.7 8.4 11 5.8 1.2 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) EF-hand_7 PF13499.1 EEA07812.1 - 2.8e-12 46.5 3.3 6.3e-06 26.2 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA07812.1 - 2e-09 36.0 7.8 0.0024 17.0 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EEA07812.1 - 8.6e-09 34.8 1.2 0.0015 18.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA07812.1 - 3.2e-08 32.5 5.6 0.00014 21.0 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EEA07812.1 - 1.3e-07 30.8 4.4 0.025 14.4 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EEA07812.1 - 0.022 14.7 1.5 0.59 10.1 0.0 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 EEA07813.1 - 3e-10 39.6 0.7 1e-09 37.9 0.5 1.9 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EEA07813.1 - 0.0089 15.8 0.0 0.034 14.0 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat HEAT PF02985.17 EEA07814.1 - 4.1e-16 57.5 2.4 0.051 13.6 0.0 9.9 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EEA07814.1 - 9.5e-07 29.0 0.0 0.56 10.5 0.0 5.8 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEA07814.1 - 0.065 13.7 0.0 13 6.3 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat tRNA-synt_1c PF00749.16 EEA07815.1 - 2.2e-98 328.8 0.0 4.2e-98 327.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEA07815.1 - 3e-37 127.9 0.0 3.1e-36 124.6 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PI31_Prot_N PF11566.3 EEA07816.1 - 6e-05 22.6 0.5 0.00019 21.0 0.3 1.8 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal Meiotic_rec114 PF03525.9 EEA07816.1 - 0.0005 18.6 0.1 0.00085 17.9 0.1 1.3 1 0 0 1 1 1 1 Meiotic recombination protein rec114 DUF4116 PF13475.1 EEA07816.1 - 0.081 12.4 0.2 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) GYF PF02213.11 EEA07817.1 - 3.4e-07 29.7 0.0 7.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 GYF domain BTB PF00651.26 EEA07817.1 - 0.007 16.3 0.1 0.044 13.7 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain DUF4100 PF13352.1 EEA07817.1 - 0.021 14.2 0.2 0.05 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) Baculo_p24 PF05073.7 EEA07817.1 - 0.064 12.8 2.3 0.096 12.2 0.5 2.1 2 1 0 2 2 2 0 Baculovirus P24 capsid protein GYF PF02213.11 EEA07818.1 - 2.6e-08 33.3 0.4 3.1e-07 29.8 0.1 2.7 3 0 0 3 3 3 1 GYF domain BTB PF00651.26 EEA07818.1 - 0.0013 18.7 0.0 0.0058 16.6 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF4339 PF14237.1 EEA07818.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) SET PF00856.23 EEA07819.1 - 8.8e-10 39.1 1.5 1.9e-09 38.0 1.0 1.5 1 0 0 1 1 1 1 SET domain AAA PF00004.24 EEA07820.1 - 9.5e-35 119.6 0.0 2.5e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA07820.1 - 1.3e-06 27.6 0.0 2.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEA07820.1 - 2e-06 27.5 0.0 6.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA07820.1 - 2.7e-06 28.1 2.8 1.8e-05 25.5 0.1 3.4 2 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EEA07820.1 - 3.5e-05 23.7 0.1 0.00042 20.2 0.0 2.8 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA07820.1 - 5.2e-05 23.3 2.9 0.1 12.7 0.3 4.4 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EEA07820.1 - 0.00011 22.0 0.0 0.00074 19.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EEA07820.1 - 0.00019 21.3 0.0 0.00097 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEA07820.1 - 0.00038 20.1 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEA07820.1 - 0.0016 18.7 0.3 0.0016 18.7 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA07820.1 - 0.0027 17.7 0.4 0.033 14.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EEA07820.1 - 0.0043 16.7 0.1 1.3 8.6 0.0 2.5 1 1 1 2 2 2 2 NACHT domain AAA_11 PF13086.1 EEA07820.1 - 0.0094 15.5 5.2 0.018 14.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 EEA07820.1 - 0.023 14.5 3.6 0.038 13.8 0.0 2.8 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EEA07820.1 - 0.031 13.3 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EEA07820.1 - 0.058 12.8 0.0 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EEA07820.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.16 EEA07821.1 - 5.9e-56 189.6 52.5 7.7e-56 189.2 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIG PF01833.19 EEA07821.1 - 5.2e-12 45.5 7.1 5.2e-05 23.1 0.5 3.8 2 1 0 2 2 2 2 IPT/TIG domain DEK_C PF08766.6 EEA07823.1 - 1.7e-06 27.6 3.6 5.2e-06 26.1 2.5 1.8 1 0 0 1 1 1 1 DEK C terminal domain AAA_11 PF13086.1 EEA07823.1 - 1.9 8.0 8.2 3.1 7.2 5.7 1.4 1 1 0 1 1 1 0 AAA domain Vfa1 PF08432.5 EEA07823.1 - 3.9 7.4 11.8 6.4 6.7 8.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 EEA07823.1 - 6.7 5.8 8.6 9.9 5.3 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 EEA07824.1 - 5.8e-44 146.4 38.7 2e-09 36.9 1.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEA07824.1 - 0.0022 17.4 0.0 0.32 10.5 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.18 EEA07825.1 - 5.6e-20 71.8 1.6 2.3e-19 69.8 1.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA07825.1 - 3.2e-13 49.5 0.0 7.1e-13 48.4 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EEA07825.1 - 7.4e-13 48.7 0.3 3.4e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal FERM_C PF09380.5 EEA07825.1 - 0.063 13.4 0.9 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 FERM C-terminal PH-like domain LSM PF01423.17 EEA07826.1 - 1.2e-11 44.0 0.0 1.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA07826.1 - 0.025 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_Rpb8 PF03870.10 EEA07827.1 - 3.2e-35 121.3 0.1 3.6e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_S26e PF01283.14 EEA07828.1 - 3e-48 162.7 12.1 3.3e-48 162.6 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PHF5 PF03660.9 EEA07828.1 - 0.03 14.3 3.4 0.037 14.0 2.3 1.1 1 0 0 1 1 1 0 PHF5-like protein SRP19 PF01922.12 EEA07828.1 - 0.068 13.7 0.2 0.1 13.1 0.1 1.4 1 1 0 1 1 1 0 SRP19 protein DnaJ PF00226.26 EEA07829.1 - 1.7e-16 59.6 0.2 1.7e-16 59.6 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain HD_3 PF13023.1 EEA07829.1 - 0.0094 15.7 3.0 0.42 10.3 0.8 2.1 2 0 0 2 2 2 2 HD domain TarH PF02203.10 EEA07829.1 - 1.1 9.0 4.0 1.2 8.9 1.9 1.8 1 1 0 1 1 1 0 Tar ligand binding domain homologue Reo_sigmaC PF04582.7 EEA07830.1 - 0.0019 17.4 5.3 0.0054 15.9 3.7 1.8 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 EEA07830.1 - 0.0099 14.5 17.0 0.02 13.5 11.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.4 EEA07830.1 - 0.013 14.4 14.1 0.027 13.3 9.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EEA07830.1 - 0.13 11.8 16.5 0.32 10.5 11.1 1.9 1 1 0 1 1 1 0 IncA protein Cep57_MT_bd PF06657.8 EEA07830.1 - 0.42 10.6 11.0 2.6 8.0 1.6 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Filament PF00038.16 EEA07830.1 - 0.66 9.3 18.2 1.6 8.1 12.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein DivIC PF04977.10 EEA07830.1 - 1.3 8.5 13.7 0.64 9.5 6.3 2.9 1 1 2 3 3 3 0 Septum formation initiator Phage_lysis PF03245.8 EEA07830.1 - 2.1 8.3 8.8 0.33 10.9 2.9 2.0 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein V_ATPase_I PF01496.14 EEA07830.1 - 4 5.1 10.0 5.7 4.6 6.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EEA07830.1 - 6.6 6.6 23.4 0.58 10.0 0.8 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EEA07830.1 - 9.2 6.7 12.8 6 7.3 0.1 3.3 3 1 1 4 4 4 0 SlyX SopA PF13981.1 EEA07831.1 - 0.021 14.8 1.5 0.024 14.6 1.1 1.2 1 0 0 1 1 1 0 SopA-like central domain ABC_tran PF00005.22 EEA07832.1 - 4.2e-05 23.8 0.0 0.00014 22.2 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EEA07832.1 - 8.6e-05 23.3 0.0 0.00038 21.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEA07832.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEA07832.1 - 0.017 15.4 1.3 0.26 11.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Cas_Cas02710 PF09670.5 EEA07832.1 - 0.028 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) T2SE PF00437.15 EEA07832.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EEA07832.1 - 0.51 9.7 0.0 1.1 8.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain La PF05383.12 EEA07833.1 - 6.6e-17 61.0 0.7 1.1e-16 60.3 0.5 1.4 1 0 0 1 1 1 1 La domain PTS_2-RNA PF01885.11 EEA07833.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Cyclin_N PF00134.18 EEA07834.1 - 2e-14 53.2 0.2 1.5e-09 37.5 0.0 3.2 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA07834.1 - 8.1e-14 51.5 0.1 1.9e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Myb_DNA-binding PF00249.26 EEA07835.1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF812 PF05667.6 EEA07835.1 - 0.069 11.6 0.1 0.089 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Rad1 PF02144.11 EEA07836.1 - 3.4e-09 35.8 1.5 5e-08 32.0 1.0 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EEA07836.1 - 0.42 9.6 7.0 0.18 10.8 0.3 2.6 2 1 1 3 3 3 0 Rad9 Metallophos PF00149.23 EEA07838.1 - 8.3e-43 146.1 0.4 1.1e-42 145.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_carr PF00153.22 EEA07839.1 - 4.2e-41 138.5 5.4 3.8e-16 58.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3753 PF12575.3 EEA07841.1 - 0.037 13.8 0.3 0.067 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) TMEM154 PF15102.1 EEA07841.1 - 0.067 12.8 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2648 PF10855.3 EEA07842.1 - 0.1 12.0 8.9 4.6 6.7 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2648) TFIID-18kDa PF02269.11 EEA07843.1 - 0.00052 19.7 0.1 0.00069 19.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit AAA_23 PF13476.1 EEA07844.1 - 8.4e-24 85.0 8.6 8.4e-24 85.0 6.0 6.0 1 1 2 3 3 1 1 AAA domain SMC_N PF02463.14 EEA07844.1 - 1.4e-11 44.0 20.8 1.2e-10 41.0 14.4 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EEA07844.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EEA07844.1 - 1.3e-06 27.7 34.3 1.3e-06 27.7 23.8 5.3 1 1 3 4 4 1 1 AAA ATPase domain AAA_29 PF13555.1 EEA07844.1 - 0.00015 21.1 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA07844.1 - 0.00026 21.1 2.2 0.42 10.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EEA07844.1 - 0.0012 18.8 0.1 0.0012 18.8 0.0 6.0 1 1 2 4 4 3 2 AAA domain AAA_13 PF13166.1 EEA07844.1 - 0.002 16.6 0.0 0.002 16.6 0.0 7.0 2 1 4 7 7 7 3 AAA domain ABC_tran PF00005.22 EEA07844.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 5.9 4 2 0 4 4 2 2 ABC transporter AAA_19 PF13245.1 EEA07844.1 - 0.022 14.4 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EEA07844.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Sua5_yciO_yrdC PF01300.13 EEA07845.1 - 1.4e-43 148.2 0.0 1.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EEA07845.1 - 1.6e-10 41.1 0.0 2.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Actin PF00022.14 EEA07846.1 - 1.7e-36 125.5 0.0 3e-26 91.7 0.0 2.2 1 1 1 2 2 2 2 Actin O-FucT PF10250.4 EEA07847.1 - 7.7e-40 137.0 6.5 1.2e-39 136.4 4.5 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FTHFS PF01268.14 EEA07847.1 - 0.076 10.9 0.0 0.13 10.1 0.0 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Radical_SAM PF04055.16 EEA07848.1 - 3.6e-10 40.2 3.8 1.7e-09 38.0 2.6 2.1 1 1 0 1 1 1 1 Radical SAM superfamily PTPA PF03095.10 EEA07850.1 - 5.2e-101 337.7 1.0 5.9e-101 337.5 0.7 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Erf4 PF10256.4 EEA07850.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF1829 PF08862.5 EEA07850.1 - 0.095 12.9 0.1 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Actin PF00022.14 EEA07851.1 - 1.1e-68 231.4 0.0 1.4e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA07851.1 - 0.002 16.8 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Proteasome PF00227.21 EEA07852.1 - 1.3e-34 119.1 0.6 1.6e-34 118.8 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Filamin PF00630.14 EEA07857.1 - 9.8e-16 58.1 0.0 3.1e-07 30.8 0.0 3.0 2 0 0 2 2 2 2 Filamin/ABP280 repeat Ctr PF04145.10 EEA07858.1 - 1.3e-23 83.6 16.4 2e-12 47.3 0.2 2.0 1 1 1 2 2 2 2 Ctr copper transporter family NADHdeh_related PF10125.4 EEA07858.1 - 0.0057 15.8 1.3 0.0064 15.6 0.9 1.1 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein Sugar_transport PF06800.7 EEA07858.1 - 0.0065 15.5 1.5 0.0075 15.3 1.0 1.0 1 0 0 1 1 1 1 Sugar transport protein HXXEE PF13787.1 EEA07858.1 - 0.07 13.4 5.5 0.098 13.0 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF1049 PF06305.6 EEA07858.1 - 0.13 11.7 4.9 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cytochrom_C_asm PF01578.15 EEA07858.1 - 0.13 11.7 6.5 0.16 11.4 4.5 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein H_PPase PF03030.11 EEA07858.1 - 0.18 10.0 1.9 0.2 9.8 1.3 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF3533 PF12051.3 EEA07858.1 - 0.27 9.9 5.7 0.32 9.6 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EEA07858.1 - 0.74 8.7 10.6 0.92 8.4 7.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein YjgP_YjgQ PF03739.9 EEA07858.1 - 0.95 8.1 6.8 1.8 7.2 4.6 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2628 PF10947.3 EEA07858.1 - 2.7 7.8 6.3 1 9.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF3963 PF13124.1 EEA07858.1 - 3.2 7.6 8.2 0.55 10.0 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) RDD PF06271.7 EEA07858.1 - 4.4 7.2 9.4 15 5.5 6.5 1.8 1 1 0 1 1 1 0 RDD family Porin_3 PF01459.17 EEA07859.1 - 5.9e-32 111.0 0.3 7.3e-32 110.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2219 PF09982.4 EEA07859.1 - 0.0089 14.8 0.1 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2219) Pro_isomerase PF00160.16 EEA07860.1 - 2.8e-40 138.0 1.5 9.5e-40 136.3 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Abhydrolase_5 PF12695.2 EEA07861.1 - 6.8e-16 58.3 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA07861.1 - 1.4e-07 31.5 0.0 6.8e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA07861.1 - 0.0002 20.9 0.2 0.0043 16.6 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Arf PF00025.16 EEA07862.1 - 9.3e-20 70.5 0.0 4.6e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 EEA07862.1 - 1.3e-05 24.5 0.0 0.0059 15.8 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit T2SE PF00437.15 EEA07862.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EEA07862.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEA07862.1 - 0.022 14.4 0.0 0.096 12.3 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EEA07862.1 - 0.025 14.7 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EEA07862.1 - 0.032 14.7 0.0 0.068 13.6 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein CAP_C PF08603.6 EEA07862.1 - 0.069 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Ras PF00071.17 EEA07862.1 - 0.075 12.4 0.0 0.87 8.9 0.0 2.1 1 1 0 2 2 2 0 Ras family AAA_32 PF13654.1 EEA07862.1 - 0.088 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA07862.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zinc_ribbon_6 PF14599.1 EEA07863.1 - 2.5e-19 68.8 0.7 2.5e-19 68.8 0.5 4.8 5 1 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 EEA07863.1 - 1.6e-11 44.1 20.9 1.6e-11 44.1 14.5 5.2 2 2 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EEA07863.1 - 6.8e-08 32.2 3.4 6.8e-08 32.2 2.4 6.1 4 3 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.1 EEA07863.1 - 2.8e-07 30.1 2.5 2.8e-07 30.1 1.7 6.2 4 3 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA07863.1 - 1.8e-06 27.8 2.9 1.8e-06 27.8 2.0 6.2 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA07863.1 - 0.00016 21.2 1.4 0.00016 21.2 1.0 4.4 4 1 1 5 5 5 1 RING-type zinc-finger Rtf2 PF04641.7 EEA07863.1 - 0.0002 20.6 1.0 0.00039 19.6 0.7 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 EEA07863.1 - 0.0011 18.7 3.5 0.0011 18.7 2.4 5.5 4 1 3 7 7 7 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 EEA07863.1 - 0.088 12.2 0.2 0.088 12.2 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif WD40 PF00400.27 EEA07864.1 - 5.5e-22 76.7 27.1 7.9e-10 38.2 1.0 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEA07864.1 - 4.3e-19 69.0 6.4 8.7e-19 68.0 4.4 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Glyco_hydro_2_C PF02836.12 EEA07864.1 - 0.0051 15.7 0.1 0.01 14.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Na_Ca_ex PF01699.19 EEA07866.1 - 1.6e-42 144.3 35.0 1.4e-23 83.0 9.6 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.20 EEA07867.1 - 3.6e-58 196.7 0.0 5e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07867.1 - 1.4e-34 119.3 0.0 3.7e-33 114.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07867.1 - 2.4e-07 30.0 0.1 1.7e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like zf-Apc11 PF12861.2 EEA07868.1 - 1.2e-26 92.4 9.7 1.4e-26 92.0 6.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEA07868.1 - 3.7e-26 91.0 11.2 4.4e-26 90.8 7.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEA07868.1 - 2.4e-07 30.4 17.1 9.4e-07 28.5 11.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA07868.1 - 5.4e-05 22.8 13.5 0.0011 18.6 9.1 2.2 1 1 1 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA07868.1 - 5.9e-05 22.6 14.9 0.015 14.9 9.1 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07868.1 - 8e-05 22.2 14.7 0.0004 19.9 9.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07868.1 - 0.00065 19.6 15.3 0.0096 15.9 7.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA07868.1 - 0.00071 19.1 13.4 0.00091 18.7 1.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEA07868.1 - 0.00084 19.1 2.7 0.00084 19.1 1.9 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-HIT PF04438.11 EEA07868.1 - 0.032 13.8 1.9 0.032 13.8 1.3 2.2 2 0 0 2 2 2 0 HIT zinc finger C1_1 PF00130.17 EEA07868.1 - 0.13 12.0 10.4 3.8 7.3 0.0 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.3 EEA07868.1 - 0.16 11.5 4.6 0.36 10.3 3.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 EEA07868.1 - 0.2 11.8 9.0 0.57 10.3 6.3 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EEA07868.1 - 0.23 11.4 14.7 1.9 8.5 9.9 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEA07868.1 - 0.32 10.7 7.5 0.87 9.3 4.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 EEA07868.1 - 0.66 9.4 3.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2256 PF10013.4 EEA07868.1 - 1.9 8.3 8.9 3.6 7.4 0.1 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HC5HC2H_2 PF13832.1 EEA07868.1 - 2 8.4 10.4 0.69 9.9 4.7 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain Elf1 PF05129.8 EEA07868.1 - 2.1 8.0 5.4 7.8 6.2 1.4 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 EEA07868.1 - 2.8 7.8 12.4 25 4.7 5.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF4451 PF14616.1 EEA07868.1 - 4.3 7.1 7.3 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) RecR PF02132.10 EEA07868.1 - 7.7 6.0 8.3 8.6 5.8 0.9 3.0 3 0 0 3 3 3 0 RecR protein Opy2 PF09463.5 EEA07868.1 - 9 6.4 11.7 34 4.6 0.0 2.6 2 1 0 2 2 2 0 Opy2 protein OB_NTP_bind PF07717.11 EEA07869.1 - 3.2e-26 91.3 0.0 8e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA07869.1 - 1.1e-23 83.1 0.0 2.6e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA07869.1 - 2.8e-12 46.3 0.0 6.9e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA07869.1 - 5.1e-07 29.3 0.0 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA07869.1 - 0.00013 22.0 0.0 0.00044 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA07869.1 - 0.0059 15.5 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EEA07869.1 - 0.075 13.3 0.1 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EEA07869.1 - 0.077 12.7 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EEA07869.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Acetyltransf_1 PF00583.19 EEA07870.1 - 3e-18 65.6 0.0 4.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA07870.1 - 1.7e-10 40.8 0.1 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA07870.1 - 2e-09 37.6 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA07870.1 - 5.1e-07 29.3 0.0 7.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEA07870.1 - 1e-06 28.6 0.1 1.4e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA07870.1 - 6.7e-06 26.1 0.1 8.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA07870.1 - 0.0008 19.3 0.0 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA07870.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EEA07870.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MSP1b PF03429.8 EEA07871.1 - 0.058 11.2 0.2 0.076 10.8 0.1 1.0 1 0 0 1 1 1 0 Major surface protein 1B Ank_2 PF12796.2 EEA07872.1 - 6.3e-40 135.4 7.2 8.4e-16 58.0 0.1 4.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA07872.1 - 7.6e-26 90.0 3.7 4.4e-07 30.2 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EEA07872.1 - 1e-23 81.8 7.2 3.9e-06 26.4 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EEA07872.1 - 2.5e-21 73.5 10.4 0.0017 18.4 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EEA07872.1 - 6.8e-18 64.3 4.3 0.0028 17.8 0.1 6.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 EEA07872.1 - 3e-12 45.9 3.9 3.2e-09 36.3 1.1 3.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEA07872.1 - 7.5e-07 28.5 1.5 0.3 11.0 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA07872.1 - 4.7e-06 25.9 4.6 0.031 13.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA07872.1 - 0.021 14.9 0.1 1.1 9.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RVP PF00077.15 EEA07872.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease TPR_8 PF13181.1 EEA07872.1 - 0.088 12.6 5.2 0.73 9.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat WBS_methylT PF12589.3 EEA07873.1 - 2.9e-19 69.3 3.9 4.3e-19 68.7 2.7 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EEA07873.1 - 2.6e-09 37.4 0.0 5.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA07873.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA07873.1 - 3.6e-05 23.3 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA07873.1 - 0.00017 22.1 0.0 0.00027 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07873.1 - 0.00024 21.4 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA07873.1 - 0.00096 19.5 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EEA07873.1 - 0.01 15.9 0.0 0.063 13.3 0.0 2.2 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 EEA07873.1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EEA07873.1 - 0.038 13.0 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EEA07873.1 - 0.064 12.9 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEA07873.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LSM PF01423.17 EEA07874.1 - 2.6e-19 68.4 0.0 3.2e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_M24 PF00557.19 EEA07875.1 - 4.4e-45 153.8 0.0 6.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEA07875.1 - 1.6e-06 27.8 3.6 4.7e-06 26.3 2.5 1.8 1 0 0 1 1 1 1 MYND finger Peptidase_M2 PF01401.13 EEA07875.1 - 0.029 12.5 0.0 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme RNA_pol_A_bac PF01000.21 EEA07876.1 - 3.8e-25 88.2 0.0 1.3e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEA07876.1 - 6.8e-19 66.7 0.0 8.5e-19 66.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 EEA07876.1 - 0.0039 17.5 0.6 0.0039 17.5 0.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEA07876.1 - 0.017 15.3 0.7 0.017 15.3 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 EEA07876.1 - 0.022 14.3 2.3 0.022 14.3 1.6 2.7 3 0 0 3 3 3 0 4Fe-4S binding domain RRM_1 PF00076.17 EEA07878.1 - 2.8e-48 161.4 0.0 2.3e-21 75.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07878.1 - 1.3e-35 121.1 0.0 2.1e-15 56.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07878.1 - 3e-30 103.8 0.2 6.5e-11 41.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA07878.1 - 0.0013 18.4 0.0 0.0051 16.5 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Zw10 PF06248.8 EEA07879.1 - 8.4e-29 100.1 10.6 8.4e-29 100.1 7.3 2.0 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 DUF438 PF04282.8 EEA07879.1 - 0.038 13.7 0.2 0.22 11.3 0.2 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) AAA PF00004.24 EEA07880.1 - 2e-14 53.9 0.2 8.6e-14 51.8 0.0 2.2 2 1 1 3 3 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEA07880.1 - 0.0006 19.9 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EEA07880.1 - 0.00068 19.3 0.2 0.013 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA07880.1 - 0.00087 19.3 0.3 0.01 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Adeno_IVa2 PF02456.10 EEA07880.1 - 0.0015 17.2 0.5 0.082 11.5 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_14 PF13173.1 EEA07880.1 - 0.0022 17.8 0.4 0.034 14.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EEA07880.1 - 0.0033 17.5 0.1 0.095 12.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA07880.1 - 0.0036 16.4 0.0 0.009 15.1 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EEA07880.1 - 0.0043 17.3 0.1 0.012 15.9 0.0 1.9 2 1 0 2 2 1 1 ABC transporter IstB_IS21 PF01695.12 EEA07880.1 - 0.0074 15.7 0.3 2.3 7.5 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.8 EEA07880.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 EEA07880.1 - 0.019 14.3 0.8 0.68 9.3 0.3 2.4 2 0 0 2 2 2 0 Guanylate kinase MMR_HSR1 PF01926.18 EEA07880.1 - 0.02 14.8 0.1 0.11 12.4 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EEA07880.1 - 0.022 15.5 0.1 0.32 11.8 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA07880.1 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEA07880.1 - 0.033 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EEA07880.1 - 0.042 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EEA07880.1 - 0.1 11.7 0.1 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EEA07880.1 - 0.1 11.6 0.0 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EEA07880.1 - 0.1 12.2 1.5 0.57 9.8 0.0 2.9 3 1 0 4 4 4 0 NACHT domain AAA_29 PF13555.1 EEA07880.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain YchF-GTPase_C PF06071.8 EEA07881.1 - 4.1e-40 135.4 0.4 8.6e-40 134.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EEA07881.1 - 6.3e-17 61.5 0.0 3.3e-16 59.2 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA07881.1 - 8.2e-07 28.4 0.0 3e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 EEA07881.1 - 0.016 16.0 0.0 0.24 12.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 EEA07881.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2779 PF11074.3 EEA07881.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) AAA_14 PF13173.1 EEA07881.1 - 0.067 13.0 0.0 0.33 10.8 0.0 2.2 2 2 0 2 2 2 0 AAA domain SecA_PP_bind PF01043.15 EEA07881.1 - 0.067 13.5 0.4 0.23 11.8 0.0 2.1 1 1 1 2 2 2 0 SecA preprotein cross-linking domain TGS PF02824.16 EEA07881.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TGS domain RNA_pol_Rpb2_6 PF00562.23 EEA07882.1 - 7.8e-113 377.1 0.0 1.1e-112 376.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA07882.1 - 7.9e-37 126.1 0.0 2.5e-36 124.5 0.0 1.8 2 1 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EEA07882.1 - 3.2e-22 78.0 0.0 8.3e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EEA07882.1 - 1.8e-17 63.3 0.0 4.2e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EEA07882.1 - 1.8e-08 34.1 0.0 6.8e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain DUF2012 PF09430.5 EEA07884.1 - 7.5e-10 38.7 0.2 9.9e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Cna_B PF05738.8 EEA07884.1 - 0.00016 21.3 0.4 0.00034 20.2 0.0 1.7 2 0 0 2 2 2 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 EEA07884.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.8 EEA07884.1 - 0.0077 15.9 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Y_Y_Y domain MVIN PF03023.9 EEA07884.1 - 0.073 11.4 0.9 0.08 11.3 0.0 1.4 2 0 0 2 2 2 0 MviN-like protein DUF2258 PF10015.4 EEA07884.1 - 0.078 12.8 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Ufm1 PF03671.9 EEA07885.1 - 2.5e-36 123.2 0.5 2.9e-36 123.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Rad60-SLD PF11976.3 EEA07885.1 - 0.024 14.3 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.18 EEA07885.1 - 0.036 14.5 0.1 0.2 12.1 0.0 1.9 1 1 1 2 2 2 0 Ras association (RalGDS/AF-6) domain Cadherin-like PF12733.2 EEA07885.1 - 0.11 12.7 0.6 0.9 9.8 0.1 1.9 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Med7 PF05983.6 EEA07886.1 - 1.3e-26 93.3 2.6 1.6e-26 93.0 1.8 1.0 1 0 0 1 1 1 1 MED7 protein DUF641 PF04859.7 EEA07886.1 - 0.022 14.5 3.0 0.033 13.9 2.0 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 EEA07886.1 - 0.069 12.9 1.5 0.091 12.5 1.1 1.3 1 0 0 1 1 1 0 Laminin Domain II AAA_23 PF13476.1 EEA07886.1 - 1 9.6 6.3 1.3 9.2 4.4 1.1 1 0 0 1 1 1 0 AAA domain TRM13 PF05206.9 EEA07887.1 - 1.3e-34 119.6 10.4 3.9e-23 82.0 2.8 3.7 1 1 2 3 3 3 2 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EEA07887.1 - 6.4e-06 25.4 1.4 6.4e-06 25.4 0.9 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.1 EEA07887.1 - 0.0021 17.7 0.1 0.012 15.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain SNARE PF05739.14 EEA07889.1 - 1.6e-15 56.5 2.9 1.6e-15 56.5 2.0 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEA07889.1 - 3.4e-15 56.0 6.9 6.5e-15 55.1 0.9 2.6 2 0 0 2 2 2 1 Syntaxin Bac_thur_toxin PF01338.13 EEA07889.1 - 0.00035 19.8 5.3 0.00045 19.5 0.5 2.3 2 1 0 2 2 2 1 Bacillus thuringiensis toxin Lipoprotein_7 PF01540.11 EEA07889.1 - 0.00054 19.1 4.6 0.014 14.5 0.4 2.9 2 1 0 2 2 2 1 Adhesin lipoprotein Tup_N PF08581.5 EEA07889.1 - 0.0095 16.1 2.7 0.0095 16.1 1.9 3.0 3 1 0 3 3 3 1 Tup N-terminal Ribonuc_2-5A PF06479.7 EEA07889.1 - 0.014 15.2 0.7 0.014 15.2 0.5 2.8 3 1 1 4 4 4 0 Ribonuclease 2-5A DUF4208 PF13907.1 EEA07889.1 - 0.048 13.8 4.2 0.066 13.4 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) Syntaxin-6_N PF09177.6 EEA07889.1 - 0.061 13.7 8.6 3.9 7.9 0.1 3.3 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EEA07889.1 - 0.12 12.2 7.8 0.44 10.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Vac_Fusion PF02346.11 EEA07889.1 - 0.77 9.2 4.1 2.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Corona_S2 PF01601.11 EEA07889.1 - 0.89 7.5 11.6 0.2 9.6 0.8 2.5 1 1 1 3 3 3 0 Coronavirus S2 glycoprotein Syntaxin_2 PF14523.1 EEA07889.1 - 1.1 9.3 10.0 1.4 8.9 2.8 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Snapin_Pallidin PF14712.1 EEA07889.1 - 1.1 9.5 9.6 11 6.3 1.8 3.5 3 1 0 3 3 3 0 Snapin/Pallidin Baculo_PEP_C PF04513.7 EEA07889.1 - 1.1 9.0 8.7 4 7.2 0.1 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 EEA07889.1 - 1.2 8.6 7.3 1.4 8.4 0.4 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG5 PF10392.4 EEA07889.1 - 2 8.4 10.0 1.3 8.9 0.1 3.3 3 2 0 3 3 3 0 Golgi transport complex subunit 5 NYD-SP28 PF14772.1 EEA07889.1 - 3.2 7.8 9.0 0.17 12.0 0.6 2.6 3 1 0 3 3 3 0 Sperm tail Cortex-I_coil PF09304.5 EEA07889.1 - 4.3 7.4 9.8 2.2 8.3 1.4 3.0 3 1 0 3 3 3 0 Cortexillin I, coiled coil DASH_Dad1 PF08649.5 EEA07889.1 - 5.2 6.8 9.3 3.4 7.4 0.5 3.5 4 0 0 4 4 4 0 DASH complex subunit Dad1 DNA_repr_REX1B PF14966.1 EEA07889.1 - 6.6 7.1 9.0 1.4 9.3 0.5 3.2 2 2 1 3 3 3 0 DNA repair REX1-B Apolipoprotein PF01442.13 EEA07889.1 - 9.4 5.6 10.1 9.2 5.7 3.0 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain CPSF_A PF03178.10 EEA07890.1 - 1.1e-33 116.7 2.1 4.1e-31 108.2 1.5 2.8 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 EEA07890.1 - 1.3e-16 59.8 0.9 1.1e-15 56.7 0.6 2.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pkinase PF00069.20 EEA07891.1 - 2e-45 154.9 0.1 4.9e-45 153.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07891.1 - 8.6e-32 110.2 0.0 1.6e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA07891.1 - 2.1e-08 33.5 0.0 3.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA07891.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GARS_C PF02843.11 EEA07891.1 - 0.052 13.7 0.3 18 5.5 0.0 3.2 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Ubie_methyltran PF01209.13 EEA07892.1 - 5.5e-73 244.9 1.6 1.3e-71 240.4 1.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEA07892.1 - 1.4e-14 53.9 0.0 2.6e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA07892.1 - 6.7e-13 48.9 0.0 9.8e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA07892.1 - 9.9e-08 32.3 0.1 3.5e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA07892.1 - 1.5e-07 31.7 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA07892.1 - 2.8e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA07892.1 - 6.6e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEA07892.1 - 0.0056 16.3 0.1 0.019 14.6 0.0 1.9 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EEA07892.1 - 0.051 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EEA07892.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) YccV-like PF08755.6 EEA07893.1 - 2.9e-20 72.0 0.2 7.5e-20 70.7 0.1 1.8 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.8 EEA07893.1 - 0.0083 16.9 0.0 0.0083 16.9 0.0 3.7 4 1 0 4 4 4 1 Glucosidase II beta subunit-like protein Utp21 PF04192.7 EEA07894.1 - 1.2e-37 129.2 0.4 2e-37 128.5 0.3 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EEA07894.1 - 1.3e-10 40.7 12.0 0.0034 17.2 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ECH_C PF13766.1 EEA07894.1 - 0.059 13.5 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region LSM PF01423.17 EEA07896.1 - 1.6e-21 75.6 1.0 2.6e-21 74.9 0.7 1.3 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EEA07896.1 - 0.03 14.1 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain V-SNARE_C PF12352.3 EEA07897.1 - 9.8e-11 41.5 1.2 9.8e-11 41.5 0.8 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEA07897.1 - 5.5e-06 25.9 2.6 8.7e-06 25.3 0.2 2.3 2 1 1 3 3 3 1 Sec20 CCDC84 PF14968.1 EEA07897.1 - 0.11 12.0 0.6 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 HATPase_c PF02518.21 EEA07898.1 - 3.3e-11 42.9 0.0 5.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEA07898.1 - 2.1e-07 30.6 0.0 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3298 PF11738.3 EEA07898.1 - 0.0083 16.6 0.2 0.019 15.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3298) XAP5 PF04921.9 EEA07899.1 - 7.7e-65 218.7 4.3 1.1e-64 218.3 3.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4046 PF13255.1 EEA07899.1 - 0.037 12.7 3.1 0.025 13.3 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) Pkinase PF00069.20 EEA07900.1 - 7.4e-36 123.6 0.0 7.8e-17 61.2 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07900.1 - 2.9e-10 39.6 0.0 0.00048 19.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase DnaJ PF00226.26 EEA07901.1 - 1.2e-11 44.1 2.1 6.6e-11 41.7 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain 14-3-3 PF00244.15 EEA07902.1 - 2e-34 118.7 0.4 2.2e-34 118.5 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_7 PF13176.1 EEA07902.1 - 0.015 15.0 0.0 58 3.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CGI-121 PF08617.5 EEA07903.1 - 4.8e-19 68.6 8.3 5.6e-19 68.3 5.8 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Ribosomal_L27e PF01777.13 EEA07904.1 - 1e-23 83.2 2.6 1.4e-23 82.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEA07904.1 - 3.3e-05 23.4 0.0 5.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KOW motif ATHILA PF03078.10 EEA07904.1 - 0.05 12.1 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family DnaB_bind PF10410.4 EEA07904.1 - 0.051 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Endonuc-MspI PF09208.5 EEA07904.1 - 0.11 11.6 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease MspI ER_lumen_recept PF00810.13 EEA07905.1 - 2.2e-42 145.0 4.5 2.2e-42 145.0 3.1 2.0 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EEA07905.1 - 0.034 13.6 0.2 0.034 13.6 0.1 3.7 2 1 1 4 4 4 0 PQ loop repeat Glycolytic PF00274.14 EEA07906.1 - 2e-163 542.7 0.1 2.2e-163 542.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I WD40 PF00400.27 EEA07907.1 - 2.9e-05 23.7 11.9 0.14 12.1 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat SF-assemblin PF06705.6 EEA07908.1 - 0.0058 15.8 7.1 0.0058 15.8 5.0 2.8 1 1 2 3 3 3 2 SF-assemblin/beta giardin Med2 PF11214.3 EEA07908.1 - 0.061 13.3 1.2 0.061 13.3 0.8 3.2 1 1 2 3 3 3 0 Mediator complex subunit 2 DUF1633 PF07794.6 EEA07908.1 - 0.13 10.1 3.7 0.079 10.9 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1633) Sec23_helical PF04815.10 EEA07908.1 - 0.84 9.0 3.7 5.3 6.5 0.1 3.0 1 1 0 2 2 2 0 Sec23/Sec24 helical domain PAS_6 PF08348.6 EEA07908.1 - 1.3 8.5 9.5 6 6.4 4.0 2.9 1 1 1 2 2 2 0 YheO-like PAS domain TIM PF00121.13 EEA07909.1 - 2.4e-89 298.5 0.1 2.7e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Hyccin PF09790.4 EEA07909.1 - 0.071 11.9 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Hyccin Cation_efflux PF01545.16 EEA07910.1 - 2e-60 204.3 13.0 2.3e-60 204.0 9.0 1.0 1 0 0 1 1 1 1 Cation efflux family Cation_ATPase_C PF00689.16 EEA07910.1 - 0.6 9.6 15.5 0.11 11.9 7.1 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus ERGIC_N PF13850.1 EEA07910.1 - 6.2 6.8 10.7 1.2 9.1 0.4 3.4 3 1 1 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Polysacc_deac_1 PF01522.16 EEA07911.1 - 2.1e-11 43.5 0.0 5.8e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase zf-TRM13_CCCH PF11722.3 EEA07911.1 - 0.063 12.6 0.5 2.9 7.3 0.1 2.5 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein RRM_1 PF00076.17 EEA07913.1 - 1.1e-05 24.9 0.0 0.0076 15.8 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07913.1 - 9.3e-05 22.2 0.1 0.0022 17.8 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07913.1 - 0.0012 18.7 0.0 0.25 11.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Spc97_Spc98 PF04130.8 EEA07915.1 - 0.00015 20.2 24.0 0.00026 19.4 16.0 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family tRNA_synt_1c_R1 PF04558.10 EEA07915.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Condensation PF00668.15 EEA07916.1 - 2.7e-09 36.3 0.0 1.4e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Condensation domain AATase PF07247.7 EEA07916.1 - 4.3e-07 28.8 0.4 4.3e-07 28.8 0.3 3.1 2 2 1 3 3 3 1 Alcohol acetyltransferase BUD22 PF09073.5 EEA07916.1 - 0.17 10.9 7.1 0.3 10.1 4.9 1.3 1 0 0 1 1 1 0 BUD22 Sas10 PF09368.5 EEA07917.1 - 6.2e-24 83.9 11.2 1.3e-23 82.9 4.4 3.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EEA07917.1 - 4.5e-15 55.6 10.2 7.4e-15 54.9 1.0 3.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family MutS_II PF05188.12 EEA07917.1 - 0.93 9.5 5.4 2 8.4 0.1 3.4 2 1 1 3 3 3 0 MutS domain II FlgN PF05130.7 EEA07917.1 - 4.7 7.4 14.3 13 5.9 0.6 3.2 2 1 0 2 2 2 0 FlgN protein ADK PF00406.17 EEA07918.1 - 6.1e-43 146.2 0.0 7.8e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EEA07918.1 - 2.4e-12 47.2 0.1 4.6e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA07918.1 - 3.9e-09 36.5 0.0 5.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA07918.1 - 1.9e-06 28.6 0.1 4e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEA07918.1 - 0.00021 20.7 0.0 0.079 12.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EEA07918.1 - 0.0082 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 EEA07918.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA07918.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EEA07918.1 - 0.098 12.1 0.1 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EEA07918.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Cyclin_N PF00134.18 EEA07919.1 - 3.8e-09 36.1 1.1 7.8e-09 35.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Suf PF05843.9 EEA07920.1 - 4.8e-10 39.6 1.7 6.1e-06 26.1 0.2 3.5 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EEA07920.1 - 0.024 14.8 0.4 0.65 10.3 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PH PF00169.24 EEA07921.1 - 0.013 15.6 0.2 0.013 15.6 0.2 5.3 5 2 0 5 5 5 0 PH domain FERM_C PF09380.5 EEA07921.1 - 0.088 13.0 3.2 0.17 12.0 0.1 3.0 3 0 0 3 3 3 0 FERM C-terminal PH-like domain Vma12 PF11712.3 EEA07924.1 - 6.1e-15 55.1 0.0 8.8e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase GBP PF02263.14 EEA07925.1 - 5.1e-09 35.5 1.1 6.2e-05 22.1 0.0 2.8 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain EF-hand_7 PF13499.1 EEA07926.1 - 1.6e-07 31.3 0.8 8.7e-07 28.9 0.5 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA07926.1 - 3.4e-07 29.6 1.2 0.064 13.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EEA07926.1 - 2.7e-06 26.9 1.9 0.0015 18.0 0.3 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA07926.1 - 3.7e-06 25.8 3.4 0.078 12.3 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EEA07926.1 - 0.0016 17.6 0.3 1.4 8.3 0.0 3.0 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EEA07926.1 - 0.045 13.7 0.1 1.4 8.9 0.0 2.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 EEA07927.1 - 1.5e-28 99.6 0.0 2.7e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA07927.1 - 5.8e-08 32.1 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Rav1p_C PF12234.3 EEA07928.1 - 2.9e-12 45.5 0.0 2.9e-12 45.5 0.0 3.5 4 0 0 4 4 4 2 RAVE protein 1 C terminal UPF0167 PF03691.9 EEA07929.1 - 0.093 12.1 5.0 0.71 9.2 1.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DUF2116 PF09889.4 EEA07929.1 - 0.11 12.2 5.0 1.6 8.6 1.0 2.6 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NUC153 PF08159.7 EEA07931.1 - 0.00086 18.8 0.9 0.0023 17.5 0.6 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EEA07931.1 - 0.016 15.0 0.0 28 4.7 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Adaptin_binding PF10199.4 EEA07932.1 - 1.7e-11 44.5 0.8 4.9e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 dTMP_synthase PF02593.9 EEA07932.1 - 0.12 11.6 0.8 0.18 11.0 0.6 1.3 1 0 0 1 1 1 0 Thymidylate synthase Abhydrolase_2 PF02230.11 EEA07933.1 - 1.3e-48 165.3 0.2 4.4e-47 160.3 0.2 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA07933.1 - 3.8e-09 36.4 0.0 5.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEA07933.1 - 4e-05 23.1 0.0 5.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEA07933.1 - 0.00082 19.3 0.0 0.0087 15.9 0.0 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEA07933.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 EEA07933.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EEA07933.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EEA07933.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MAT1 PF06391.8 EEA07934.1 - 2.8e-06 27.0 13.7 2.8e-06 27.0 9.5 2.3 2 1 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.1 EEA07934.1 - 3.6e-06 26.6 3.8 7.7e-06 25.6 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA07934.1 - 9e-06 25.3 6.0 2.4e-05 23.9 4.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA07934.1 - 3.2e-05 23.5 7.1 6.9e-05 22.4 4.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07934.1 - 7.2e-05 22.7 8.3 0.00026 20.9 5.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA07934.1 - 0.00023 20.9 1.5 0.00023 20.9 1.1 2.8 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEA07934.1 - 0.0014 18.2 10.9 0.0072 15.9 7.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Porphobil_deam PF01379.15 EEA07934.1 - 0.0022 16.9 0.1 0.0034 16.3 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain DPRP PF04244.8 EEA07934.1 - 0.0055 16.2 3.4 0.017 14.6 0.8 2.0 1 1 1 2 2 2 1 Deoxyribodipyrimidine photo-lyase-related protein zf-NADH-PPase PF09297.6 EEA07934.1 - 0.031 13.7 1.7 1.3 8.6 0.1 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FYVE PF01363.16 EEA07934.1 - 0.043 13.7 2.9 0.093 12.6 2.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.1 EEA07934.1 - 0.07 12.7 4.9 0.32 10.6 3.4 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EEA07934.1 - 3.3 7.6 7.2 4.4 7.2 1.8 2.6 1 1 1 2 2 2 0 IBR domain zf-RING_UBOX PF13445.1 EEA07934.1 - 3.6 7.3 11.4 0.86 9.3 2.4 3.3 2 1 1 3 3 3 0 RING-type zinc-finger Cyclin_N PF00134.18 EEA07935.1 - 1.4e-06 27.8 2.8 1.6e-06 27.6 0.2 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain zf-C3HC4 PF00097.20 EEA07936.1 - 1.2e-09 37.6 10.2 2.7e-09 36.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07936.1 - 5.8e-07 29.4 10.1 5.8e-07 29.4 7.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA07936.1 - 3.6e-06 26.7 4.6 0.00017 21.3 4.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.3 EEA07936.1 - 0.00018 20.9 5.3 0.00028 20.3 3.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EEA07936.1 - 0.0004 20.2 9.7 0.00084 19.1 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EEA07936.1 - 0.00043 19.8 5.3 0.00043 19.8 3.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEA07936.1 - 0.00062 19.5 3.9 0.0013 18.4 2.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EEA07936.1 - 0.0011 18.6 9.4 0.0026 17.4 6.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA07936.1 - 0.067 13.0 2.0 0.17 11.7 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA07936.1 - 2 8.0 10.0 20 4.8 7.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEA07936.1 - 2.1 8.1 7.3 6.2 6.6 5.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EEA07936.1 - 3.3 7.6 7.4 15 5.5 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Corona_NS2 PF04753.7 EEA07937.1 - 0.014 15.2 0.5 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Coronavirus non-structural protein NS2 Transgly PF00912.17 EEA07937.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase CLTH PF10607.4 EEA07937.1 - 0.46 10.1 3.7 1.2 8.8 2.5 1.9 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Hydrolase_3 PF08282.7 EEA07938.1 - 2.3e-42 145.3 0.1 6.9e-42 143.7 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEA07938.1 - 6.2e-17 61.7 0.0 1.9e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EEA07938.1 - 3.8e-06 27.4 0.0 0.00017 22.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EEA07938.1 - 0.00027 19.9 0.1 0.00058 18.8 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase DUF3834 PF12916.2 EEA07938.1 - 0.0071 15.3 0.0 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3834) HAD PF12710.2 EEA07938.1 - 0.026 14.6 0.1 0.98 9.5 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA07938.1 - 0.086 12.5 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase_3 PF08282.7 EEA07939.1 - 2e-45 155.3 0.2 2.4e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEA07939.1 - 2e-16 60.0 0.0 8.2e-14 51.4 0.0 2.5 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EEA07939.1 - 0.0002 21.8 0.1 0.079 13.3 0.0 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA07939.1 - 0.00086 19.5 0.0 0.02 15.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EEA07939.1 - 0.018 13.9 0.0 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 Trehalose-phosphatase BLOC1_2 PF10046.4 EEA07939.1 - 0.034 14.2 0.2 0.081 13.0 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAD_2 PF13419.1 EEA07939.1 - 0.092 12.9 0.0 10 6.3 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IMS_C PF11799.3 EEA07939.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain TBCA PF02970.11 EEA07940.1 - 8.8e-16 57.7 1.2 8.8e-16 57.7 0.9 1.5 2 0 0 2 2 2 1 Tubulin binding cofactor A CENP-F_leu_zip PF10473.4 EEA07940.1 - 0.0017 18.2 0.7 0.0017 18.2 0.5 1.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.11 EEA07940.1 - 0.07 13.3 0.4 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Rapamycin_bind PF08771.6 EEA07940.1 - 0.096 12.7 1.7 0.4 10.7 0.2 2.1 2 0 0 2 2 2 0 Rapamycin binding domain DUF1203 PF06718.6 EEA07941.1 - 0.087 12.6 0.5 1 9.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1203) IncA PF04156.9 EEA07941.1 - 4.2 6.9 10.9 6.6 6.2 7.6 1.4 1 0 0 1 1 1 0 IncA protein LPP20 PF02169.11 EEA07941.1 - 8.1 6.6 7.5 0.53 10.4 1.1 1.9 2 1 0 2 2 2 0 LPP20 lipoprotein Peptidase_M41 PF01434.13 EEA07942.1 - 1.5e-63 214.0 0.0 2.4e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEA07942.1 - 2.2e-42 144.3 0.0 5.1e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA07942.1 - 7.3e-07 30.0 0.0 2e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsH_ext PF06480.10 EEA07942.1 - 1.4e-05 25.2 0.4 4e-05 23.7 0.3 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EEA07942.1 - 4.5e-05 23.2 0.0 0.00019 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA07942.1 - 0.00016 21.7 0.2 0.011 15.9 0.1 2.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA07942.1 - 0.00021 20.1 0.3 0.00097 17.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 EEA07942.1 - 0.00089 19.1 0.0 0.0083 16.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA07942.1 - 0.0019 17.2 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEA07942.1 - 0.0026 17.2 0.1 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEA07942.1 - 0.0027 17.6 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEA07942.1 - 0.0034 17.1 1.2 0.014 15.1 0.7 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EEA07942.1 - 0.0064 16.4 0.1 0.022 14.7 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EEA07942.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EEA07942.1 - 0.024 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEA07942.1 - 0.026 13.9 0.4 0.07 12.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EEA07942.1 - 0.031 13.4 0.2 0.068 12.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA07942.1 - 0.043 14.1 1.2 0.25 11.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EEA07942.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.27 EEA07942.1 - 1.2 8.6 0.0 1.2 8.6 0.0 3.4 4 0 0 4 4 3 0 EF hand CS PF04969.11 EEA07943.1 - 5.2e-06 26.9 4.4 0.00022 21.6 2.9 2.6 1 1 0 1 1 1 1 CS domain zf-met PF12874.2 EEA07945.1 - 0.00012 22.1 0.5 0.00012 22.1 0.3 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type S6PP PF05116.8 EEA07946.1 - 9.3e-36 123.3 0.0 7.8e-17 61.3 0.0 3.2 2 1 1 3 3 3 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EEA07946.1 - 7.8e-12 45.2 3.6 5.9e-11 42.4 2.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4506 PF14958.1 EEA07947.1 - 0.0069 15.9 1.9 0.019 14.5 0.1 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4506) MAR_sialic_bdg PF10564.4 EEA07947.1 - 3.2 7.5 7.7 0.23 11.2 0.8 2.3 3 0 0 3 3 3 0 Sialic-acid binding micronemal adhesive repeat DUF904 PF06005.7 EEA07948.1 - 0.0028 17.9 1.7 0.0028 17.9 1.2 9.1 5 3 1 6 6 6 1 Protein of unknown function (DUF904) Dsl1_N PF11988.3 EEA07949.1 - 0.12 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal Exostosin PF03016.10 EEA07952.1 - 1.1e-07 31.1 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Exostosin family DUF4083 PF13314.1 EEA07952.1 - 0.76 9.6 3.8 0.99 9.2 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) BUD22 PF09073.5 EEA07954.1 - 0.027 13.5 0.2 0.037 13.0 0.1 1.1 1 0 0 1 1 1 0 BUD22 STAG PF08514.6 EEA07955.1 - 0.0012 18.5 0.1 0.016 14.9 0.0 3.1 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 EEA07955.1 - 0.1 12.7 0.4 11 6.3 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Rad50_zn_hook PF04423.9 EEA07956.1 - 0.11 12.0 4.0 3 7.3 0.1 4.2 4 0 0 4 4 4 0 Rad50 zinc hook motif Bax1-I PF01027.15 EEA07958.1 - 6.7e-26 91.1 32.2 8.2e-26 90.8 22.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3353 PF11833.3 EEA07958.1 - 3.2 7.1 10.7 0.07 12.5 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) tRNA-synt_1b PF00579.20 EEA07959.1 - 1.1e-55 188.8 0.0 1.6e-55 188.3 0.0 1.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Folate_rec PF03024.9 EEA07960.1 - 6.7e-16 58.3 10.5 6.7e-16 58.3 7.3 1.8 1 1 1 2 2 2 1 Folate receptor family DUF2013 PF09431.5 EEA07961.1 - 0.041 13.6 5.7 0.019 14.7 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2013) Fer2 PF00111.22 EEA07962.1 - 1.9e-10 40.3 1.9 2.3e-10 40.0 1.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 EEA07963.1 - 2.4e-77 254.5 0.0 3.7e-20 71.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA07963.1 - 5.8e-58 192.7 0.0 2.5e-17 62.6 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA07963.1 - 2.3e-37 126.6 0.0 1.2e-08 34.6 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEA07963.1 - 2.5e-29 100.7 0.9 7.1e-29 99.2 0.5 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EEA07963.1 - 7.6e-06 25.7 0.0 0.57 10.0 0.0 3.8 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 EEA07963.1 - 0.0023 17.6 0.0 6.6 6.5 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEA07963.1 - 0.048 13.4 0.0 12 5.7 0.0 3.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 EEA07963.1 - 4.7 5.1 10.2 6.5 4.6 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RCC1 PF00415.13 EEA07965.1 - 1.6e-30 105.0 0.1 5.8e-11 42.4 0.1 7.3 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA07965.1 - 1.3e-27 94.6 17.7 6.4e-07 28.8 0.1 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat zf-RING_UBOX PF13445.1 EEA07966.1 - 3.1e-14 52.4 5.2 1.3e-13 50.4 3.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA07966.1 - 2.2e-06 27.4 4.4 5.4e-06 26.1 3.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEA07966.1 - 4.7e-06 26.5 4.6 4.7e-06 26.5 3.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07966.1 - 7.6e-06 25.5 4.3 1.6e-05 24.5 3.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA07966.1 - 1.1e-05 25.1 3.9 2e-05 24.3 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain CLTH PF10607.4 EEA07966.1 - 2.9e-05 23.8 19.7 2.9e-05 23.8 13.6 3.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-C3HC4 PF00097.20 EEA07966.1 - 0.00011 21.8 6.2 0.00011 21.8 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA07966.1 - 0.00013 21.5 3.9 0.00024 20.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EEA07966.1 - 0.0017 17.8 5.0 0.0042 16.5 3.5 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Peptidase_M41 PF01434.13 EEA07966.1 - 0.012 15.1 0.3 0.03 13.7 0.2 1.7 1 0 0 1 1 1 0 Peptidase family M41 zf-RING_4 PF14570.1 EEA07966.1 - 0.13 11.9 3.6 0.27 10.8 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EEA07966.1 - 0.22 11.1 6.7 0.069 12.7 2.1 2.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 TPR_11 PF13414.1 EEA07967.1 - 0.0014 18.2 1.7 0.003 17.1 0.3 2.2 2 0 0 2 2 2 1 TPR repeat Amido_AtzD_TrzD PF09663.5 EEA07967.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) DUF2762 PF10960.3 EEA07968.1 - 4.5 7.0 7.1 9.7 5.9 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) Spectrin PF00435.16 EEA07969.1 - 0.0041 17.3 2.6 0.01 16.1 1.8 1.7 1 0 0 1 1 1 1 Spectrin repeat HSBP1 PF06825.7 EEA07969.1 - 0.095 12.2 0.5 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Git3_C PF11970.3 EEA07969.1 - 0.12 12.1 0.4 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF948 PF06103.6 EEA07969.1 - 5.3 6.9 9.4 0.42 10.5 2.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) XPG_I PF00867.13 EEA07970.1 - 0.14 12.2 1.0 0.78 9.8 0.0 2.6 3 0 0 3 3 3 0 XPG I-region CotJB PF12652.2 EEA07971.1 - 0.082 12.9 0.1 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 CotJB protein ELK PF03789.8 EEA07971.1 - 0.082 12.7 0.4 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 ELK domain AvrE PF11725.3 EEA07972.1 - 1.5 5.7 0.0 2.2 5.2 0.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor zf-met2 PF12907.2 EEA07973.1 - 5.5e-18 64.6 3.0 8.1e-18 64.1 2.1 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EEA07973.1 - 1.2e-05 25.8 3.1 2.1e-05 25.1 2.2 1.4 1 0 0 1 1 1 1 4F5 protein family Rhodanese PF00581.15 EEA07974.1 - 0.0026 18.0 0.1 0.0058 16.9 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain TAA-Trp-ring PF15401.1 EEA07977.1 - 0.69 10.1 6.4 0.11 12.6 0.4 2.4 3 0 0 3 3 3 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Sec7 PF01369.15 EEA07978.1 - 2.9e-48 164.0 0.5 2.9e-48 164.0 0.3 2.1 2 0 0 2 2 2 1 Sec7 domain RabGAP-TBC PF00566.13 EEA07978.1 - 7.6e-30 103.9 3.0 7.6e-30 103.9 2.1 2.8 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Rad9 PF04139.8 EEA07979.1 - 1.1e-17 64.0 0.4 1.8e-17 63.3 0.3 1.3 1 0 0 1 1 1 1 Rad9 INCENP_ARK-bind PF03941.10 EEA07980.1 - 1e-05 25.2 0.3 2.7e-05 23.8 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region zf-C3HC4_2 PF13923.1 EEA07981.1 - 2.9e-05 24.0 3.1 2.9e-05 24.0 2.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA07981.1 - 0.0027 17.3 3.3 0.0027 17.3 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Methyltransf_15 PF09445.5 EEA07981.1 - 0.017 14.6 0.4 0.021 14.4 0.3 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase zf-C3HC4_3 PF13920.1 EEA07981.1 - 0.031 13.9 2.0 0.031 13.9 1.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07981.1 - 0.031 14.0 1.9 0.031 14.0 1.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain DZF PF07528.9 EEA07981.1 - 0.082 12.2 0.2 11 5.3 0.0 2.1 2 0 0 2 2 2 0 DZF domain zf-C3HC4_4 PF15227.1 EEA07981.1 - 0.4 10.5 5.8 0.37 10.6 1.6 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEA07981.1 - 1.1 9.0 8.0 1.1 9.1 4.4 2.0 2 1 0 2 2 2 0 Ring finger domain Sel1 PF08238.7 EEA07982.1 - 6.9e-34 115.5 21.6 2.2e-09 37.6 0.0 9.9 10 0 0 10 10 10 9 Sel1 repeat Ribosomal_S19 PF00203.16 EEA07983.1 - 4.8e-28 96.5 0.0 6.8e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L4 PF00573.17 EEA07984.1 - 4e-40 137.2 0.0 6.6e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EEA07984.1 - 9.9e-20 70.2 0.8 3.1e-19 68.6 0.6 1.9 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain TrbM PF07424.6 EEA07985.1 - 0.0025 17.8 6.2 0.0025 17.8 4.3 3.3 2 2 0 3 3 3 1 TrbM Reo_sigmaC PF04582.7 EEA07985.1 - 9.4 5.3 13.0 0.43 9.7 1.4 3.1 1 1 2 4 4 4 0 Reovirus sigma C capsid protein DEAD PF00270.24 EEA07986.1 - 1.2e-44 151.7 0.2 3.1e-44 150.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA07986.1 - 3.8e-24 84.3 2.3 5.5e-24 83.8 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA07986.1 - 4.7e-05 23.2 0.9 0.0002 21.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit S4 PF01479.20 EEA07986.1 - 0.022 14.2 0.2 14 5.2 0.0 3.5 3 0 0 3 3 3 0 S4 domain DUF1442 PF07279.6 EEA07986.1 - 0.031 13.3 0.1 0.067 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Sugar_transport PF06800.7 EEA07987.1 - 0.038 13.0 0.1 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein Na_trans_assoc PF06512.8 EEA07987.1 - 0.47 10.3 2.8 0.75 9.7 1.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Ras PF00071.17 EEA07988.1 - 2.7e-67 225.1 1.1 3.2e-67 224.9 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA07988.1 - 1.4e-21 77.2 0.1 2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA07988.1 - 1.5e-17 63.3 0.2 1.8e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA07988.1 - 2.8e-08 33.1 0.1 3.4e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA07988.1 - 1.2e-06 28.0 0.3 2.8e-06 26.8 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA07988.1 - 4.7e-05 23.3 0.1 7.4e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEA07988.1 - 0.0001 21.5 0.1 0.00016 20.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EEA07988.1 - 0.00039 19.6 0.0 0.0032 16.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA07988.1 - 0.00078 19.5 0.0 0.0012 19.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EEA07988.1 - 0.0046 16.2 0.1 0.076 12.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EEA07988.1 - 0.018 15.0 0.1 0.05 13.5 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EEA07988.1 - 0.039 13.8 0.2 0.1 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA07988.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EEA07988.1 - 0.043 12.5 4.7 0.46 9.1 0.6 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 EEA07988.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EEA07988.1 - 0.079 12.5 1.8 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEA07988.1 - 0.097 12.9 0.4 0.27 11.5 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EEA07988.1 - 0.11 12.7 0.1 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nol1_Nop2_Fmu PF01189.12 EEA07989.1 - 3e-85 286.0 0.0 4e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EEA07989.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEA07989.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gpi16 PF04113.9 EEA07990.1 - 4.8e-32 110.7 0.8 1.5e-31 109.1 0.6 1.7 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Bestrophin PF01062.16 EEA07991.1 - 0.00063 18.7 0.1 0.001 18.0 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3510 PF12022.3 EEA07991.1 - 0.16 12.1 0.2 0.16 12.1 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF3510) DUF342 PF03961.8 EEA07991.1 - 0.16 10.3 3.2 0.22 9.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Methyltransf_3 PF01596.12 EEA07992.1 - 0.031 13.3 1.0 0.071 12.1 0.7 1.5 1 0 0 1 1 1 0 O-methyltransferase JAB PF01398.16 EEA07993.1 - 3.8e-34 116.8 0.0 7.3e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEA07993.1 - 5.3e-20 71.6 2.0 1.1e-19 70.5 1.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EEA07993.1 - 1.2e-10 40.8 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EEA07993.1 - 0.025 14.0 0.2 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Alpha-amylase_C PF02806.13 EEA07994.1 - 6.1e-19 67.9 0.2 1e-17 64.0 0.0 2.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EEA07994.1 - 6.2e-18 64.6 0.1 6.2e-18 64.6 0.0 3.2 6 0 0 6 6 6 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 EEA07994.1 - 2.3e-14 53.5 0.0 4.2e-07 29.6 0.0 2.8 1 1 1 2 2 2 2 Alpha amylase, catalytic domain RNA_pol_Rpb1_5 PF04998.12 EEA07995.1 - 2.4e-92 309.1 0.0 3.8e-92 308.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EEA07995.1 - 9.5e-75 251.9 0.0 9.5e-75 251.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EEA07995.1 - 1.3e-65 220.4 0.0 4.1e-65 218.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEA07995.1 - 1.2e-35 122.5 0.0 3.9e-35 120.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEA07995.1 - 8.7e-30 102.6 0.0 3.8e-29 100.5 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-CCCH PF00642.19 EEA07996.1 - 8.9e-09 34.8 2.5 8.9e-09 34.8 1.7 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EEA07996.1 - 2.3e-06 27.1 7.1 4.1e-06 26.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA07996.1 - 2.7e-06 27.2 10.1 5.8e-06 26.2 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA07996.1 - 2.6e-05 23.8 11.7 5.2e-05 22.8 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA07996.1 - 4.5e-05 23.1 10.4 9.2e-05 22.1 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEA07996.1 - 0.001 18.7 6.7 0.0026 17.4 4.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EEA07996.1 - 0.0024 17.4 11.1 0.006 16.2 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EEA07996.1 - 0.0052 16.0 3.3 0.0052 16.0 2.3 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-P11 PF03854.9 EEA07996.1 - 0.42 10.1 7.5 1.2 8.6 5.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EEA07996.1 - 1.8 8.5 8.8 15 5.5 6.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PUB PF09409.5 EEA07997.1 - 6.6e-09 35.4 3.0 1.5e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 PUB domain SPX PF03105.14 EEA07998.1 - 3e-29 102.6 12.0 1.5e-28 100.4 6.7 2.7 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EEA07998.1 - 4.2e-13 49.2 0.9 1.1e-12 47.9 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ribosomal_L32e PF01655.13 EEA07999.1 - 7.5e-46 154.7 0.4 9.3e-46 154.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Glyco_transf_34 PF05637.7 EEA08000.1 - 0.0067 15.9 1.3 0.018 14.5 0.7 1.8 2 1 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family FYVE PF01363.16 EEA08001.1 - 0.0023 17.7 6.9 0.0068 16.2 4.8 1.8 1 0 0 1 1 1 1 FYVE zinc finger DUF837 PF05769.6 EEA08001.1 - 0.025 14.1 1.5 0.025 14.1 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF837) DnaB_bind PF10410.4 EEA08001.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Microtub_assoc PF07989.6 EEA08001.1 - 0.54 10.1 14.2 0.18 11.6 0.4 3.3 2 1 1 3 3 3 0 Microtubule associated Siva PF05458.7 EEA08001.1 - 0.66 9.5 5.5 1.7 8.1 3.8 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) KLRAQ PF10205.4 EEA08001.1 - 1.7 8.7 12.7 0.47 10.5 0.6 3.8 2 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein Mod_r PF07200.8 EEA08001.1 - 2.7 7.9 13.0 0.16 11.9 0.6 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein zf-B_box PF00643.19 EEA08001.1 - 4.3 7.2 11.1 2.5 8.0 4.4 2.4 2 0 0 2 2 2 0 B-box zinc finger DUF904 PF06005.7 EEA08001.1 - 6.6 7.1 16.1 0.92 9.8 5.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) NLE PF08154.7 EEA08002.1 - 1.8e-16 59.8 0.2 3.4e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.27 EEA08002.1 - 2.8e-11 42.8 14.4 0.038 13.8 1.4 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat DUF2525 PF10733.4 EEA08002.1 - 0.066 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) eRF1_2 PF03464.10 EEA08003.1 - 4.3e-44 150.0 0.2 1.1e-43 148.6 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 EEA08003.1 - 1.4e-39 134.8 0.2 3e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEA08003.1 - 5.6e-25 87.4 0.0 9.7e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EEA08003.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PI3_PI4_kinase PF00454.22 EEA08004.1 - 9.1e-28 97.3 0.7 2.5e-27 95.8 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Exo_endo_phos PF03372.18 EEA08005.1 - 7.4e-21 75.2 0.2 1.8e-20 73.9 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3447 PF11929.3 EEA08005.1 - 0.1 12.4 1.1 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DUF676 PF05057.9 EEA08006.1 - 5.1e-22 78.2 0.0 2.3e-21 76.0 0.0 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EEA08006.1 - 0.001 18.7 0.0 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEA08006.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA08006.1 - 0.0027 17.6 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA08006.1 - 0.0098 15.4 0.1 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Syntaxin-6_N PF09177.6 EEA08007.1 - 2.2e-11 43.9 3.3 2.8e-11 43.6 0.4 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.8 EEA08007.1 - 0.066 12.5 5.6 0.14 11.5 0.7 2.4 1 1 1 2 2 2 0 fzo-like conserved region SNARE PF05739.14 EEA08007.1 - 4.8 6.9 9.5 0.28 10.8 0.6 3.3 5 0 0 5 5 5 0 SNARE domain A_deaminase PF00962.17 EEA08008.1 - 7.7e-81 271.5 0.0 2.9e-80 269.6 0.0 2.0 2 1 0 2 2 2 1 Adenosine/AMP deaminase EF-hand_1 PF00036.27 EEA08008.1 - 0.092 12.1 1.4 0.17 11.2 0.1 2.3 2 0 0 2 2 2 0 EF hand Exo_endo_phos PF03372.18 EEA08012.1 - 2.5e-16 60.3 0.0 3.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RyR PF02026.11 EEA08012.1 - 0.03 14.3 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 RyR domain DEAD PF00270.24 EEA08013.1 - 1.9e-36 125.0 0.1 1.5e-35 122.1 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08013.1 - 1.2e-21 76.2 0.1 5.5e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA08013.1 - 2.4e-13 49.3 0.1 8.9e-13 47.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA08013.1 - 0.00067 19.5 1.2 0.00067 19.5 0.8 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Tctex-1 PF03645.8 EEA08014.1 - 2.4e-28 97.9 1.3 3e-28 97.6 0.9 1.1 1 0 0 1 1 1 1 Tctex-1 family KAR PF15222.1 EEA08014.1 - 0.011 15.8 0.3 0.018 15.0 0.2 1.4 1 0 0 1 1 1 0 Kidney androgen-regulated Mating_N PF12731.2 EEA08014.1 - 0.079 12.8 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 DELLA PF12041.3 EEA08014.1 - 0.085 12.5 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal zf-RING_5 PF14634.1 EEA08018.1 - 0.022 14.4 12.0 0.053 13.2 8.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA08018.1 - 0.16 12.0 13.1 0.38 10.8 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA08018.1 - 1.1 9.1 12.0 2.3 8.1 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EEA08018.1 - 1.7 8.3 18.0 0.22 11.2 9.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AIM24 PF01987.12 EEA08019.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 DUF747 PF05346.6 EEA08020.1 - 1.4e-92 310.2 27.5 3.1e-83 279.5 11.8 2.8 3 0 0 3 3 3 2 Eukaryotic membrane protein family PGAP1 PF07819.8 EEA08021.1 - 8.6e-07 28.7 0.0 3.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEA08021.1 - 0.0098 15.7 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA PF00004.24 EEA08022.1 - 1.4e-80 267.9 0.4 1e-47 161.6 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEA08022.1 - 3.9e-12 46.3 0.2 6.8e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEA08022.1 - 1.6e-10 40.4 0.0 0.00037 19.6 0.0 3.4 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA08022.1 - 9e-09 35.5 0.0 0.012 15.6 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EEA08022.1 - 2.8e-08 33.6 0.5 0.028 14.1 0.2 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA08022.1 - 3.1e-08 33.8 7.6 0.0008 19.5 0.5 5.3 3 2 0 3 3 3 2 AAA domain TIP49 PF06068.8 EEA08022.1 - 4.8e-08 32.1 0.5 0.0023 16.7 0.0 3.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 EEA08022.1 - 7.6e-08 32.3 1.0 0.0079 16.0 0.1 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EEA08022.1 - 5.7e-07 30.3 1.6 0.0023 18.7 0.1 3.8 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EEA08022.1 - 7.3e-06 25.2 0.1 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA08022.1 - 8.4e-06 26.1 7.2 1.1e-05 25.7 0.6 4.0 4 1 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 EEA08022.1 - 1.2e-05 24.8 0.0 0.062 12.7 0.0 3.1 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_19 PF13245.1 EEA08022.1 - 1.3e-05 24.8 0.0 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EEA08022.1 - 2.1e-05 24.6 0.0 0.27 11.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EEA08022.1 - 6.9e-05 22.3 0.0 1.8 7.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 EEA08022.1 - 0.00016 21.9 0.0 0.067 13.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 EEA08022.1 - 0.00026 20.6 0.0 0.031 13.9 0.0 3.4 3 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.1 EEA08022.1 - 0.0009 18.8 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EEA08022.1 - 0.0012 18.4 0.0 0.47 9.9 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EEA08022.1 - 0.0014 18.2 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EEA08022.1 - 0.0015 18.5 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEA08022.1 - 0.0021 16.9 0.0 0.057 12.2 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EEA08022.1 - 0.0037 17.1 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEA08022.1 - 0.0056 16.2 0.1 0.21 11.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EEA08022.1 - 0.0082 15.2 0.0 3.7 6.5 0.0 2.9 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.7 EEA08022.1 - 0.0087 15.1 0.0 3.9 6.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.11 EEA08022.1 - 0.013 14.7 0.1 1.2 8.3 0.0 2.9 3 0 0 3 3 2 0 PhoH-like protein UPF0079 PF02367.12 EEA08022.1 - 0.058 13.0 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EEA08022.1 - 0.077 12.9 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3895 PF13034.1 EEA08022.1 - 0.15 11.5 6.1 0.15 11.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) CBFD_NFYB_HMF PF00808.18 EEA08023.1 - 1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA08023.1 - 2.5e-05 24.3 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cnd1 PF12717.2 EEA08024.1 - 7e-25 87.8 7.4 7e-25 87.8 5.2 5.0 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 NOG1 PF06858.9 EEA08025.1 - 1.5e-26 92.0 0.3 4.5e-26 90.4 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EEA08025.1 - 5.1e-25 86.9 1.6 1.2e-24 85.7 1.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EEA08025.1 - 7.2e-18 64.6 0.0 2.5e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA08025.1 - 1.4e-10 40.6 0.0 2.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEA08025.1 - 0.0055 17.1 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEA08025.1 - 0.0071 16.1 0.1 1.4 8.7 0.0 2.8 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 EEA08025.1 - 0.015 14.4 0.0 0.041 13.0 0.0 1.8 2 0 0 2 2 2 0 AIG1 family DUF258 PF03193.11 EEA08025.1 - 0.069 12.3 0.0 0.46 9.6 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEA08025.1 - 0.37 11.0 4.7 9.2 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Peptidase_M16 PF00675.15 EEA08026.1 - 4e-10 39.6 0.1 1.9e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA08026.1 - 2.5e-09 37.0 2.1 2.9e-06 27.0 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16_C PF05193.16 EEA08027.1 - 3.1e-10 40.0 2.1 2e-09 37.3 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA08027.1 - 2.4e-09 37.0 0.0 5.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF4366 PF14283.1 EEA08029.1 - 0.074 12.4 5.3 0.13 11.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Nucleoplasmin PF03066.10 EEA08029.1 - 5.8 6.4 13.0 15 5.0 9.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin EF-hand_1 PF00036.27 EEA08030.1 - 1.1e-33 111.9 14.1 1.4e-08 33.4 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEA08030.1 - 4.9e-28 94.4 9.1 1.4e-07 30.8 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EEA08030.1 - 9.6e-28 96.1 10.1 1.8e-14 53.6 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA08030.1 - 6e-23 80.2 9.9 7.5e-12 44.6 1.0 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EEA08030.1 - 2.2e-18 64.6 12.0 7.4e-05 21.9 0.2 4.8 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 EEA08030.1 - 3.6e-14 52.4 0.6 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA08030.1 - 1.5e-05 24.6 4.7 0.011 15.5 0.0 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Alpha-E PF04168.7 EEA08030.1 - 0.0049 16.2 0.2 1.4 8.2 0.1 2.0 1 1 0 2 2 2 2 A predicted alpha-helical domain with a conserved ER motif. DUF3164 PF11363.3 EEA08030.1 - 0.0089 15.4 1.2 0.67 9.3 0.0 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF3164) DUF1636 PF07845.6 EEA08030.1 - 0.036 14.2 0.0 1 9.5 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1636) MgtE_N PF03448.12 EEA08030.1 - 0.049 13.9 4.9 0.084 13.1 1.1 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain UPF0231 PF06062.6 EEA08030.1 - 0.11 12.4 3.5 0.44 10.4 0.6 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) Toprim_2 PF13155.1 EEA08030.1 - 0.25 11.6 3.2 5.9 7.2 0.1 2.5 1 1 1 2 2 2 0 Toprim-like DUF3887 PF13026.1 EEA08030.1 - 3.5 7.9 8.0 3 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) PEPcase PF00311.12 EEA08031.1 - 4.2e-228 759.1 4.9 1.3e-133 446.6 0.9 4.2 3 1 0 3 3 3 3 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EEA08031.1 - 3.7e-06 25.5 0.0 0.00017 20.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase DUF445 PF04286.7 EEA08032.1 - 0.045 13.2 10.2 0.04 13.4 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RNB PF00773.14 EEA08032.1 - 0.13 11.5 18.8 0.37 10.0 8.5 2.2 1 1 1 2 2 2 0 RNB domain Thioredoxin PF00085.15 EEA08033.1 - 3.3e-18 65.2 0.0 4.4e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EEA08033.1 - 3.2e-05 23.8 0.0 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_8 PF13905.1 EEA08033.1 - 5.5e-05 23.2 0.1 0.001 19.1 0.0 2.5 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA08033.1 - 0.0028 17.8 0.0 0.01 16.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EEA08033.1 - 0.0029 17.4 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EEA08033.1 - 0.019 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Toxin-deaminase PF14424.1 EEA08033.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DNA_pol_A_exo1 PF01612.15 EEA08035.1 - 1.6e-36 125.4 0.0 3.8e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 EEA08035.1 - 5e-08 32.5 0.1 1.9e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 HRDC domain MazG PF03819.12 EEA08036.1 - 2.7e-05 24.0 0.3 5.2e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain Myb_DNA-binding PF00249.26 EEA08037.1 - 1.5e-19 69.7 5.3 1.8e-10 40.6 0.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 EEA08037.1 - 5.6e-19 68.2 5.5 5.6e-19 68.2 3.8 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EEA08037.1 - 3.9e-14 52.4 6.3 1.2e-11 44.5 1.7 4.4 4 1 1 5 5 5 2 Myb-like DNA-binding domain tRNA_m1G_MT PF01746.16 EEA08038.1 - 1.6e-19 70.2 0.2 1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase DUF1041 PF06292.12 EEA08038.1 - 1.5 8.9 5.1 13 5.9 0.5 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1041) C2 PF00168.25 EEA08039.1 - 4e-26 90.6 0.0 9.6e-08 31.7 0.0 5.3 6 0 0 6 6 6 4 C2 domain PI3K_C2 PF00792.19 EEA08039.1 - 0.0069 16.1 0.0 0.13 12.0 0.0 3.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 ArfGap PF01412.13 EEA08040.1 - 1.1e-26 92.9 0.7 2.1e-26 91.9 0.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 EEA08040.1 - 0.0016 18.2 1.0 0.0028 17.4 0.7 1.4 1 0 0 1 1 1 1 B-box zinc finger SNF2_N PF00176.18 EEA08041.1 - 1.6e-31 109.2 0.6 4.1e-31 107.8 0.4 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA08041.1 - 4.1e-08 32.9 0.0 1.9e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA08041.1 - 1.8e-05 24.6 5.3 1.9e-05 24.5 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEA08041.1 - 0.0097 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ATP-synt_ab PF00006.20 EEA08041.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EEA08041.1 - 0.47 9.9 0.0 0.47 9.9 0.0 3.3 3 2 1 4 4 4 0 AAA domain NADH-u_ox-rdase PF10785.4 EEA08042.1 - 0.043 14.0 0.2 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Rdx PF10262.4 EEA08044.1 - 1.8e-09 37.4 0.0 3.2e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Rdx family AAA_assoc PF14363.1 EEA08044.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA tRNA_anti-codon PF01336.20 EEA08045.1 - 8.1e-08 32.0 0.1 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Dynein_light PF01221.13 EEA08045.1 - 0.063 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 RPA_C PF08784.6 EEA08045.1 - 0.1 13.0 0.3 0.1 13.0 0.2 2.7 2 1 0 2 2 2 0 Replication protein A C terminal LSM PF01423.17 EEA08046.1 - 0.023 14.2 1.4 0.25 10.9 0.1 2.3 2 0 0 2 2 2 0 LSM domain MBF1 PF08523.5 EEA08049.1 - 9.3e-20 70.4 1.0 9.3e-20 70.4 0.7 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EEA08049.1 - 6.6e-12 45.0 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EEA08049.1 - 1.3e-07 31.5 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EEA08049.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EEA08049.1 - 0.052 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain EF-hand_1 PF00036.27 EEA08050.1 - 3.9e-08 32.0 3.9 0.00083 18.4 0.1 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EEA08050.1 - 7.3e-07 29.2 0.2 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA08050.1 - 2.6e-06 26.8 1.6 0.0057 16.4 0.1 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EEA08050.1 - 2.7e-05 23.6 2.7 0.029 13.9 0.0 3.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 EEA08050.1 - 0.00028 20.5 0.5 0.0015 18.2 0.0 2.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EEA08050.1 - 0.0024 17.1 4.4 0.0043 16.3 0.8 2.8 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EEA08050.1 - 0.0029 17.4 0.1 1.6 8.7 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain TerB PF05099.8 EEA08050.1 - 0.013 15.1 0.1 3.7 7.2 0.0 2.5 2 1 1 3 3 3 0 Tellurite resistance protein TerB HSP90 PF00183.13 EEA08051.1 - 8.9e-254 842.8 29.8 1.3e-253 842.3 20.6 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EEA08051.1 - 7.9e-12 44.8 0.1 1.4e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEA08051.1 - 1.3e-11 44.2 0.3 1.3e-11 44.2 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EEA08051.1 - 0.013 15.3 0.1 0.048 13.4 0.1 2.0 1 0 0 1 1 1 0 Tumour suppressor protein GSH-S_ATP PF02955.11 EEA08051.1 - 0.048 12.8 0.1 0.095 11.8 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF1706 PF08020.6 EEA08051.1 - 0.19 11.2 4.8 2 7.9 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1706) AAA PF00004.24 EEA08052.1 - 2.1e-10 40.9 2.5 4.8e-05 23.5 0.2 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Ribosomal_L19e PF01280.15 EEA08053.1 - 1.7e-56 190.1 11.5 2.7e-56 189.4 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19e DUF4358 PF14270.1 EEA08053.1 - 0.054 13.3 1.5 0.085 12.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) WD40 PF00400.27 EEA08054.1 - 2.9e-06 26.9 11.6 7.7e-05 22.4 0.3 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat GATA PF00320.22 EEA08054.1 - 0.17 11.2 7.0 0.47 9.8 4.8 1.8 1 0 0 1 1 1 0 GATA zinc finger Clat_adaptor_s PF01217.15 EEA08055.1 - 5.5e-26 90.9 6.5 6.1e-26 90.8 4.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3964 PF13107.1 EEA08055.1 - 0.055 13.7 0.5 0.077 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) DNA_ligase_A_M PF01068.16 EEA08056.1 - 2.8e-58 196.6 0.8 2.8e-58 196.6 0.5 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEA08056.1 - 4.2e-40 137.4 0.0 8.1e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEA08056.1 - 8e-23 80.6 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EEA08056.1 - 0.00011 21.9 2.0 0.0012 18.6 1.4 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EEA08056.1 - 0.095 12.3 0.1 12 5.6 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain PUB PF09409.5 EEA08057.1 - 3.3e-16 58.8 1.4 1.1e-15 57.1 1.0 2.0 1 0 0 1 1 1 1 PUB domain tRNA-synt_1 PF00133.17 EEA08058.1 - 5.3e-215 714.9 0.0 1.5e-214 713.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA08058.1 - 2.9e-26 92.0 0.2 2.6e-24 85.7 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEA08058.1 - 3.5e-20 72.0 7.9 3e-07 29.4 0.1 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EEA08058.1 - 2.4e-06 26.9 0.8 6.9e-05 22.1 0.0 3.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DKCLD PF08068.7 EEA08059.1 - 2.1e-28 98.0 0.1 9e-28 95.9 0.0 2.2 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 EEA08059.1 - 1.2e-20 74.2 6.0 5e-16 59.1 0.0 3.7 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EEA08059.1 - 4e-19 68.1 2.3 8.6e-19 67.0 1.6 1.6 1 0 0 1 1 1 1 PUA domain Nuf2 PF03800.9 EEA08060.1 - 1.2e-33 116.1 0.0 1.2e-33 116.1 0.0 2.8 3 2 0 3 3 3 1 Nuf2 family ATG16 PF08614.6 EEA08060.1 - 0.0036 17.1 9.4 0.0036 17.1 6.5 4.5 1 1 3 4 4 3 1 Autophagy protein 16 (ATG16) Filament PF00038.16 EEA08060.1 - 0.0043 16.5 12.2 0.0043 16.5 8.5 3.6 1 1 2 3 3 3 1 Intermediate filament protein BRE1 PF08647.6 EEA08060.1 - 0.0046 16.8 4.1 0.0046 16.8 2.9 3.9 2 1 2 4 4 4 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EEA08060.1 - 0.0076 15.4 1.4 0.0076 15.4 1.0 2.6 1 1 2 3 3 3 1 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EEA08060.1 - 0.14 11.2 46.4 0.097 11.7 9.0 3.2 1 1 2 3 3 3 0 Tropomyosin ArsR PF09824.4 EEA08060.1 - 0.19 11.0 11.7 2 7.6 0.6 3.6 1 1 2 3 3 3 0 ArsR transcriptional regulator DUF3584 PF12128.3 EEA08060.1 - 0.78 6.9 46.3 1.2 6.4 32.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 EEA08060.1 - 0.98 8.5 54.7 0.73 8.9 10.1 3.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.1 EEA08060.1 - 3.2 7.4 7.1 2.7 7.6 1.6 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif Spc7 PF08317.6 EEA08060.1 - 8.4 4.9 53.5 0.73 8.4 10.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein HOOK PF05622.7 EEA08060.1 - 8.7 4.0 52.1 0.4 8.4 4.2 3.0 1 1 1 2 2 2 0 HOOK protein GTP_EFTU PF00009.22 EEA08062.1 - 3e-39 134.4 0.0 6.8e-39 133.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEA08062.1 - 2.2e-24 85.2 0.0 4.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEA08062.1 - 6.1e-20 70.8 0.0 2.5e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEA08062.1 - 3.5e-12 46.2 0.0 6.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA08062.1 - 6.2e-08 32.6 0.4 1.8e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.1 EEA08062.1 - 2e-07 30.7 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EEA08062.1 - 1.8e-05 25.1 0.0 6e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EEA08062.1 - 0.025 14.3 0.0 3.9 7.2 0.0 2.8 1 1 1 2 2 2 0 Dynamin family Ras PF00071.17 EEA08062.1 - 0.068 12.5 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 Ras family Ribosomal_L7Ae PF01248.21 EEA08063.1 - 2.2e-23 81.5 0.0 2.5e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.13 EEA08063.1 - 0.11 12.4 0.4 2.6 8.1 0.0 2.1 1 1 1 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1736 PF08409.6 EEA08064.1 - 1.9e-20 72.1 1.4 46 3.6 0.0 16.7 19 0 0 19 19 19 11 Domain of unknown function (DUF1736) GUCT PF08152.7 EEA08064.1 - 2.1e-06 27.6 4.5 1.1 9.2 0.0 7.5 2 1 6 9 9 9 2 GUCT (NUC152) domain 2OG-FeII_Oxy PF03171.15 EEA08065.1 - 4.8e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EEA08065.1 - 0.0019 18.7 0.0 0.0038 17.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.1 EEA08065.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.24 EEA08066.1 - 3.6e-44 150.2 0.0 2e-43 147.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08066.1 - 8.1e-21 73.6 0.0 1.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA08066.1 - 3.5e-20 71.3 0.2 7.4e-20 70.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA08066.1 - 0.0076 16.0 0.7 0.032 14.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEA08066.1 - 0.032 13.4 0.2 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EEA08066.1 - 0.13 11.8 0.0 2 7.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA08066.1 - 0.15 12.1 0.6 1.8 8.6 0.3 2.8 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA08066.1 - 0.21 11.3 0.7 0.84 9.4 0.0 2.3 2 1 0 2 2 2 0 Part of AAA domain Ribosomal_L18e PF00828.14 EEA08067.1 - 3.7e-30 104.9 0.0 5.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 TMEM154 PF15102.1 EEA08068.1 - 0.19 11.4 2.7 0.66 9.6 1.5 2.0 1 1 0 1 1 1 0 TMEM154 protein family LLC1 PF14945.1 EEA08068.1 - 2.1 8.7 4.4 20 5.5 3.1 2.2 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein PUB PF09409.5 EEA08069.1 - 3.5e-20 71.5 0.2 1e-19 70.0 0.1 1.8 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 EEA08069.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain GAGA_bind PF06217.7 EEA08069.1 - 0.61 9.9 4.5 0.8 9.6 3.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family HAUS6_N PF14661.1 EEA08069.1 - 1.2 8.3 17.2 0.6 9.4 10.4 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 EEA08069.1 - 2.5 5.8 6.4 3.1 5.5 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnd2 PF05786.9 EEA08070.1 - 4.7e-25 88.2 19.7 8.6e-13 47.7 1.0 3.4 4 0 0 4 4 4 3 Condensin complex subunit 2 RRM_1 PF00076.17 EEA08071.1 - 4.8e-13 48.5 0.0 8.9e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08071.1 - 1.3e-08 34.7 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08071.1 - 2.7e-08 33.5 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUA PF01472.15 EEA08072.1 - 2.5e-17 62.3 0.0 3.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain PixA PF12306.3 EEA08073.1 - 0.0018 18.1 1.3 0.0051 16.6 0.9 1.7 1 0 0 1 1 1 1 Inclusion body protein PEP-utilisers_N PF05524.8 EEA08073.1 - 0.12 12.1 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Yippee-Mis18 PF03226.9 EEA08074.1 - 0.047 13.7 2.6 0.27 11.2 0.1 2.9 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc-ribbons_6 PF07191.7 EEA08074.1 - 0.11 12.2 1.3 8.5 6.2 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbons DUF550 PF04447.7 EEA08075.1 - 0.12 11.9 0.2 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF550) Ish1 PF10281.4 EEA08075.1 - 0.31 11.1 2.3 1.8 8.7 0.2 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein CS PF04969.11 EEA08076.1 - 4.7e-15 55.9 5.0 4.7e-15 55.9 3.5 2.1 3 1 0 3 3 3 1 CS domain SGS PF05002.10 EEA08076.1 - 6.6e-12 45.0 2.6 2.1e-11 43.4 1.8 1.8 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 EEA08076.1 - 8.1e-09 35.4 1.9 8.1e-09 35.4 1.3 1.8 2 0 0 2 2 2 1 Siah interacting protein, N terminal DUF4180 PF13788.1 EEA08076.1 - 0.015 14.9 1.5 0.036 13.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4180) HU-DNA_bdg PF14848.1 EEA08076.1 - 0.069 12.8 2.8 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 DNA-binding domain DUF3502 PF12010.3 EEA08076.1 - 2.3 8.1 10.5 3.5 7.5 0.7 3.2 1 1 0 3 3 3 0 Domain of unknown function (DUF3502) PCI_Csn8 PF10075.4 EEA08077.1 - 2.7e-23 82.3 0.1 3.8e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEA08077.1 - 2.4e-12 46.8 3.7 3.3e-12 46.4 2.5 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Bax1-I PF01027.15 EEA08078.1 - 3e-36 124.9 33.2 3.5e-36 124.7 23.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2721 PF11026.3 EEA08078.1 - 0.00028 20.5 0.4 0.00028 20.5 0.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2721) Shisa PF13908.1 EEA08079.1 - 0.011 15.9 0.7 0.015 15.4 0.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PV-1 PF06637.6 EEA08079.1 - 0.035 12.6 0.5 0.059 11.9 0.3 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Cyclin_N PF00134.18 EEA08080.1 - 2.4e-28 98.2 0.0 4.3e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA08080.1 - 0.0044 16.9 0.3 0.0085 16.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Epsilon_antitox PF08998.6 EEA08080.1 - 0.2 11.6 1.7 18 5.4 0.1 2.6 2 1 0 2 2 2 0 Bacterial epsilon antitoxin Hira PF07569.6 EEA08081.1 - 3e-11 42.9 0.2 3e-11 42.9 0.1 2.9 4 0 0 4 4 4 1 TUP1-like enhancer of split WD40 PF00400.27 EEA08081.1 - 2.2e-05 24.1 0.1 1.3 9.0 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Sugar_tr PF00083.19 EEA08082.1 - 1.6e-55 188.5 33.0 2e-55 188.1 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA08082.1 - 3.9e-27 94.9 27.4 4.7e-19 68.3 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UBA_4 PF14555.1 EEA08083.1 - 3.2e-07 29.7 0.1 6.3e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EEA08083.1 - 2.1e-05 24.4 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like zf-UBR PF02207.15 EEA08084.1 - 4.7e-19 67.8 17.0 4.7e-19 67.8 11.8 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Ribosomal_S8e PF01201.17 EEA08085.1 - 2e-38 131.5 6.2 5.2e-38 130.1 4.3 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.3 EEA08085.1 - 0.09 12.6 2.3 0.17 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF3959 PF13105.1 EEA08085.1 - 4.5 6.5 12.2 0.052 12.8 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) TFIID_30kDa PF03540.8 EEA08087.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit WD40 PF00400.27 EEA08088.1 - 0.015 15.1 0.5 0.069 13.0 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat E1-E2_ATPase PF00122.15 EEA08089.1 - 9.8e-26 90.1 1.2 1.1e-19 70.4 0.0 3.1 2 0 0 2 2 2 2 E1-E2 ATPase HAD PF12710.2 EEA08089.1 - 1.8e-13 51.1 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA08089.1 - 5.1e-07 29.5 0.3 1.8e-06 27.8 0.2 1.9 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EEA08089.1 - 8.7e-07 29.5 0.0 0.012 15.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA08089.1 - 0.00029 20.2 0.0 0.00095 18.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RRM_6 PF14259.1 EEA08090.1 - 1.1e-33 114.9 0.0 1.1e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA08090.1 - 3.1e-33 113.2 0.0 7.6e-17 60.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08090.1 - 4.5e-18 64.8 0.1 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA08090.1 - 0.0042 16.9 0.0 1 9.2 0.0 3.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EEA08090.1 - 0.047 13.4 0.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 EEA08091.1 - 1.1e-13 50.3 38.6 3.7e-06 26.6 2.2 4.7 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 EEA08091.1 - 0.00026 20.5 28.6 0.013 15.1 0.8 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CHC2 PF01807.15 EEA08091.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.1 1 1 2 3 3 3 0 CHC2 zinc finger zf-CCHC_2 PF13696.1 EEA08091.1 - 0.12 11.8 0.1 0.12 11.8 0.1 4.1 4 0 0 4 4 4 0 Zinc knuckle Myosin_head PF00063.16 EEA08092.1 - 1.1e-122 410.4 23.7 3.5e-100 336.0 6.9 4.5 3 1 0 3 3 3 2 Myosin head (motor domain) AAA_22 PF13401.1 EEA08092.1 - 0.011 15.8 0.0 0.048 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA08092.1 - 0.12 13.1 3.6 0.34 11.7 0.0 3.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA08092.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EEA08092.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Brr6_like_C_C PF10104.4 EEA08093.1 - 1.4e-45 154.1 2.0 1.4e-45 154.1 1.4 2.0 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3603 PF12227.3 EEA08093.1 - 0.031 13.4 0.1 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Fer4_NifH PF00142.13 EEA08093.1 - 0.084 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family LRRC37AB_C PF14914.1 EEA08094.1 - 0.18 11.2 0.6 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Baculo_11_kDa PF06143.6 EEA08094.1 - 0.79 9.1 5.6 4.2 6.8 0.1 2.7 2 1 1 3 3 3 0 Baculovirus 11 kDa family LSM PF01423.17 EEA08095.1 - 1.4e-17 63.0 0.2 1.7e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Chordopox_A35R PF05989.7 EEA08095.1 - 0.0051 16.4 0.0 0.0065 16.0 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A35R protein Thioredoxin PF00085.15 EEA08096.1 - 7.6e-25 86.6 0.0 8.7e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA08096.1 - 1.4e-05 25.1 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA08096.1 - 0.0071 16.5 0.0 0.028 14.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EEA08096.1 - 0.013 15.1 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EEA08096.1 - 0.044 13.3 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EEA08096.1 - 0.046 13.2 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF3244 PF11589.3 EEA08098.1 - 0.0051 16.4 4.6 0.0051 16.4 3.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3244) AdoHcyase_NAD PF00670.16 EEA08098.1 - 0.2 11.4 1.3 0.26 11.0 0.9 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF740 PF05340.7 EEA08098.1 - 0.86 7.8 5.2 1.1 7.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF4392 PF14336.1 EEA08099.1 - 5.7e-37 127.1 0.0 8.5e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Pkinase PF00069.20 EEA08100.1 - 4.5e-36 124.3 2.0 2e-35 122.2 1.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08100.1 - 2.2e-16 59.7 0.1 5.4e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase SNF2_N PF00176.18 EEA08102.1 - 5.4e-67 225.7 0.0 5.4e-67 225.7 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEA08102.1 - 5.5e-15 55.0 0.0 1.4e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EEA08102.1 - 3.5e-14 52.4 0.0 3.5e-14 52.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.19 EEA08102.1 - 1.7e-11 43.5 0.3 1.1e-05 25.0 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PAT1 PF09770.4 EEA08102.1 - 0.0013 17.1 78.4 0.0027 16.0 54.4 1.6 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EEA08102.1 - 0.79 7.8 110.2 1.5 6.9 76.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DEAD PF00270.24 EEA08104.1 - 2.8e-35 121.3 0.0 4.7e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08104.1 - 5.4e-15 55.0 0.2 1.1e-10 41.2 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEA08104.1 - 1e-06 28.7 0.1 6.5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EEA08104.1 - 0.035 13.6 1.0 0.67 9.4 0.0 2.9 3 1 1 4 4 4 0 AAA domain RPAP1_C PF08620.5 EEA08105.1 - 1.5e-24 85.6 0.0 3.5e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal HEAT PF02985.17 EEA08105.1 - 0.012 15.6 0.1 0.047 13.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat Rep_fac-A_3 PF08661.6 EEA08106.1 - 2.2e-21 75.7 0.0 2.5e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 RNA_lig_T4_1 PF09511.5 EEA08107.1 - 4.8e-06 26.2 1.9 8.2e-05 22.1 1.3 2.6 1 1 0 1 1 1 1 RNA ligase AAA_33 PF13671.1 EEA08107.1 - 0.053 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA08107.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_ligase PF09414.5 EEA08107.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA ligase Zeta_toxin PF06414.7 EEA08107.1 - 0.2 10.7 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HSP70 PF00012.15 EEA08108.1 - 1.5e-262 871.9 8.7 1.7e-262 871.7 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA08108.1 - 9.9e-15 53.9 3.0 8.3e-13 47.6 0.5 2.5 1 1 1 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EEA08108.1 - 0.00067 19.3 0.1 0.0025 17.4 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EEA08108.1 - 0.033 14.0 7.0 8.1 6.3 3.2 4.1 2 1 0 2 2 2 0 Cell division protein FtsA Syntaxin-6_N PF09177.6 EEA08108.1 - 0.44 10.9 3.7 1.3 9.4 2.6 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Cu_amine_oxid PF01179.15 EEA08109.1 - 9e-85 284.8 0.2 1.3e-84 284.3 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.18 EEA08109.1 - 3.5e-17 62.6 0.0 8.4e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 MAM domain DUF3238 PF11579.3 EEA08110.1 - 0.049 13.2 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) DWNN PF08783.6 EEA08111.1 - 2.6e-18 65.7 0.2 6.9e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.1 EEA08111.1 - 0.00045 20.1 13.0 0.00096 19.1 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA08111.1 - 0.21 11.2 10.0 0.55 9.9 6.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA08111.1 - 0.23 11.3 12.6 0.089 12.6 6.9 1.7 2 0 0 2 2 2 0 Ring finger domain zf-UDP PF14569.1 EEA08111.1 - 0.23 11.2 6.4 1.8 8.3 3.8 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EEA08111.1 - 0.29 10.8 5.3 0.15 11.8 2.0 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EEA08111.1 - 0.58 10.0 12.9 0.67 9.8 7.2 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EEA08111.1 - 3.3 7.3 11.1 6.5 6.4 7.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PCNA_N PF00705.13 EEA08112.1 - 3.9e-36 123.3 4.7 3.9e-36 123.3 3.2 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EEA08112.1 - 1.3e-34 118.8 0.1 6.1e-31 107.0 0.0 2.3 2 1 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EEA08112.1 - 1.6e-10 40.2 0.5 6.2e-09 35.0 0.2 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EEA08112.1 - 4.2e-07 29.3 0.3 1.5e-06 27.5 0.2 1.9 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.7 EEA08112.1 - 0.0013 17.7 0.1 0.0042 16.0 0.1 1.9 1 1 0 1 1 1 1 Hus1-like protein DNA_pol3_beta_2 PF02767.11 EEA08112.1 - 0.0063 16.5 0.0 0.17 11.9 0.0 2.8 1 1 1 2 2 2 1 DNA polymerase III beta subunit, central domain RRM_1 PF00076.17 EEA08114.1 - 1.4e-12 47.0 0.8 4.4e-11 42.2 0.1 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08114.1 - 1.5e-10 40.9 0.3 2.4e-08 33.8 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08114.1 - 0.05 13.4 0.1 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Na_Ca_ex PF01699.19 EEA08116.1 - 1.4e-27 96.0 28.7 1.9e-20 72.8 7.8 3.6 3 1 1 4 4 4 2 Sodium/calcium exchanger protein zf-C2HC5 PF06221.8 EEA08117.1 - 7.1e-11 41.7 6.7 1.1e-10 41.1 4.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Rubella_E2 PF05749.6 EEA08117.1 - 0.029 13.6 0.3 0.039 13.2 0.2 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Drf_FH1 PF06346.7 EEA08118.1 - 6.2e-06 25.8 68.3 0.034 13.6 15.7 6.1 3 2 3 6 6 6 6 Formin Homology Region 1 Glyoxal_oxid_N PF07250.6 EEA08118.1 - 0.12 11.4 1.3 1.7 7.6 0.0 3.2 4 0 0 4 4 4 0 Glyoxal oxidase N-terminus Caudal_act PF04731.7 EEA08118.1 - 0.39 11.0 3.5 0.32 11.2 0.2 2.5 3 0 0 3 3 3 0 Caudal like protein activation region Peptidase_M18 PF02127.10 EEA08119.1 - 1.2e-125 419.4 0.0 1.4e-125 419.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EEA08119.1 - 2.7e-08 32.9 0.0 1.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DUF773 PF05600.7 EEA08123.1 - 2.3e-18 66.2 12.2 3.1e-16 59.2 3.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF773) Snapin_Pallidin PF14712.1 EEA08123.1 - 0.11 12.8 7.3 1.7 9.0 1.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 EEA08123.1 - 0.15 12.1 2.9 0.24 11.4 0.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BolA PF01722.13 EEA08124.1 - 1.3e-20 73.1 0.0 1.5e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CK_II_beta PF01214.13 EEA08125.1 - 6.9e-70 234.3 0.1 8.9e-70 233.9 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4205 PF13898.1 EEA08126.1 - 5.9e-51 173.2 0.4 1.1e-50 172.2 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4205) DEAD PF00270.24 EEA08127.1 - 6.6e-39 133.1 0.0 6.3e-38 129.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08127.1 - 2.8e-25 87.9 1.1 8.4e-25 86.4 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEA08127.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ctf8 PF09696.5 EEA08130.1 - 1.1e-09 38.1 0.3 2.8e-09 36.8 0.2 1.7 1 1 0 1 1 1 1 Ctf8 Neurexophilin PF06312.7 EEA08130.1 - 0.11 11.6 0.3 0.27 10.4 0.1 1.7 1 1 1 2 2 2 0 Neurexophilin zf-RING_3 PF14369.1 EEA08131.1 - 0.034 14.1 0.3 0.034 14.1 0.2 2.9 2 1 0 2 2 2 0 zinc-finger E1-E2_ATPase PF00122.15 EEA08132.1 - 3e-35 121.3 1.1 3.1e-34 118.0 0.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA08132.1 - 2.2e-23 83.7 0.0 4.6e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA08132.1 - 4e-11 43.4 2.2 1.4e-10 41.6 1.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEA08132.1 - 6.9e-07 29.3 1.0 2.1e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain NPV_P10 PF05531.7 EEA08133.1 - 0.035 14.3 2.0 0.095 12.9 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ROF PF07073.7 EEA08133.1 - 0.13 12.2 0.8 0.39 10.7 0.6 1.8 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) G-patch PF01585.18 EEA08134.1 - 1.3e-16 60.0 1.1 2.7e-16 59.0 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEA08134.1 - 2.4e-09 36.8 0.1 2.4e-09 36.8 0.1 2.4 2 1 0 2 2 2 1 DExH-box splicing factor binding site Pkinase PF00069.20 EEA08135.1 - 7.3e-49 166.2 0.0 5.1e-48 163.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08135.1 - 8.9e-21 74.1 0.0 1.8e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EEA08137.1 - 1.3e-06 28.4 5.9 0.051 13.7 0.3 4.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA08137.1 - 2.9e-06 26.1 7.7 0.022 14.0 0.5 3.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEA08137.1 - 0.00019 20.9 8.7 0.018 14.6 1.5 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA08137.1 - 0.003 17.3 9.2 0.57 10.2 0.4 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EEA08137.1 - 0.012 14.9 4.7 0.016 14.4 0.3 2.8 2 0 0 2 2 2 0 EF hand RNA_pol_Rpa2_4 PF06883.7 EEA08137.1 - 0.16 11.9 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain AAA_5 PF07728.9 EEA08139.1 - 3e-89 295.9 0.4 2.2e-21 76.0 0.0 9.6 8 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA08139.1 - 2.8e-19 69.0 0.0 0.00019 21.0 0.0 5.9 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EEA08139.1 - 5.5e-16 58.9 0.8 0.00058 20.0 0.0 5.8 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA08139.1 - 9.4e-14 51.8 0.1 0.00021 21.3 0.0 4.7 4 0 0 4 4 4 3 AAA ATPase domain AAA_33 PF13671.1 EEA08139.1 - 1.1e-12 48.0 0.0 0.0096 15.8 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.1 EEA08139.1 - 1.2e-11 44.9 0.0 0.011 15.8 0.0 6.0 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EEA08139.1 - 8.1e-11 41.3 1.3 0.042 12.7 0.0 4.4 4 0 0 4 4 4 3 Type II/IV secretion system protein Sigma54_activat PF00158.21 EEA08139.1 - 2.3e-10 40.1 0.0 0.21 11.0 0.0 5.4 6 0 0 6 6 6 3 Sigma-54 interaction domain Mg_chelatase PF01078.16 EEA08139.1 - 3.2e-08 32.9 0.0 1 8.4 0.0 5.8 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEA08139.1 - 5e-08 32.5 0.1 1.6 8.5 0.0 4.5 4 0 0 4 4 4 3 Part of AAA domain AAA_17 PF13207.1 EEA08139.1 - 2.4e-07 31.5 15.1 0.0014 19.3 0.0 7.4 7 0 0 7 7 5 1 AAA domain Sigma54_activ_2 PF14532.1 EEA08139.1 - 5.1e-07 29.8 0.0 0.36 10.8 0.0 5.6 6 0 0 6 6 4 2 Sigma-54 interaction domain ABC_tran PF00005.22 EEA08139.1 - 1.1e-06 28.9 9.4 0.028 14.6 0.0 6.1 5 0 0 5 5 4 2 ABC transporter MobB PF03205.9 EEA08139.1 - 3.3e-06 26.8 0.2 0.43 10.2 0.0 3.9 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EEA08139.1 - 2.1e-05 24.1 0.1 1.7 8.3 0.0 4.8 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EEA08139.1 - 4.8e-05 23.3 2.6 1.8 8.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EEA08139.1 - 5.2e-05 22.6 0.0 0.14 11.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.7 EEA08139.1 - 8.4e-05 22.2 0.3 2 8.0 0.0 4.0 3 0 0 3 3 3 2 NACHT domain AAA_30 PF13604.1 EEA08139.1 - 0.00016 21.3 0.0 2.1 7.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.17 EEA08139.1 - 0.002 17.5 0.2 4.1 6.7 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EEA08139.1 - 0.006 16.0 0.0 4 6.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA08139.1 - 0.0063 16.8 34.7 0.018 15.3 0.0 9.5 8 1 1 9 9 5 2 AAA domain IstB_IS21 PF01695.12 EEA08139.1 - 0.0069 15.8 0.2 7.4 5.9 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein RuvB_N PF05496.7 EEA08139.1 - 0.07 12.1 5.5 2.9 6.8 0.0 4.3 6 0 0 6 6 5 0 Holliday junction DNA helicase ruvB N-terminus CPT PF07931.7 EEA08139.1 - 0.16 11.5 0.0 20 4.7 0.0 3.7 4 0 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 EEA08139.1 - 1.1 8.6 0.0 9.8 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.12 EEA08140.1 - 2.7e-19 68.7 0.1 6.6e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain TPR_11 PF13414.1 EEA08142.1 - 2.7e-16 58.9 2.2 2.7e-10 39.7 1.5 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEA08142.1 - 1.9e-05 24.2 1.2 0.89 9.6 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA08142.1 - 0.00047 19.6 5.5 0.69 9.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DDE_Tnp_IS66 PF03050.9 EEA08142.1 - 0.0098 15.1 0.2 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 Transposase IS66 family TPR_12 PF13424.1 EEA08142.1 - 0.39 10.6 2.5 15 5.6 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EEA08142.1 - 3.5 7.5 6.1 3.7 7.5 0.3 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Herpes_UL52 PF03121.10 EEA08144.1 - 0.0013 18.3 0.8 0.0043 16.7 0.6 1.9 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Thymidylate_kin PF02223.12 EEA08145.1 - 3.7e-40 137.2 0.0 4.3e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EEA08145.1 - 0.00045 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA08145.1 - 0.0012 18.0 0.0 0.004 16.3 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EEA08145.1 - 0.024 14.9 0.1 0.058 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain BRAP2 PF07576.7 EEA08146.1 - 0.032 13.7 1.5 0.061 12.8 0.2 2.2 2 1 0 2 2 2 0 BRCA1-associated protein 2 zf-DNL PF05180.7 EEA08148.1 - 6.6e-24 83.4 1.3 9.9e-24 82.8 0.9 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-C4_Topoisom PF01396.14 EEA08148.1 - 0.059 12.8 2.6 0.27 10.7 1.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger FYVE_2 PF02318.11 EEA08149.1 - 0.024 14.5 1.3 0.069 13.0 0.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF1031 PF06275.6 EEA08150.1 - 0.053 13.5 1.0 1.5 8.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) KTSC PF13619.1 EEA08150.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.1 4 0 0 4 4 4 0 KTSC domain TRAM_LAG1_CLN8 PF03798.11 EEA08151.1 - 1e-23 83.9 16.0 1.6e-23 83.2 11.1 1.3 1 0 0 1 1 1 1 TLC domain DUF3671 PF12420.3 EEA08151.1 - 3.4 7.6 14.3 2.6 8.0 1.9 2.9 3 1 0 3 3 3 0 Protein of unknown function Sec1 PF00995.18 EEA08152.1 - 7.3e-125 417.7 8.0 8.4e-125 417.5 5.6 1.0 1 0 0 1 1 1 1 Sec1 family LSM PF01423.17 EEA08153.1 - 2.7e-08 33.2 0.1 6.9e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 LSM domain DUF1299 PF06975.6 EEA08153.1 - 0.07 13.0 0.4 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Ribosomal_S17e PF00833.13 EEA08154.1 - 5.9e-56 187.4 0.4 6.7e-56 187.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 NinE PF05322.6 EEA08154.1 - 0.12 12.0 0.0 0.6 9.8 0.0 2.1 1 1 1 2 2 2 0 NINE Protein Ank_2 PF12796.2 EEA08155.1 - 7.2e-34 115.9 5.1 2.5e-12 46.9 0.0 4.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA08155.1 - 4.4e-27 92.5 6.6 0.00077 19.1 0.0 6.8 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EEA08155.1 - 2.9e-25 87.7 5.4 1e-06 28.8 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA08155.1 - 9.1e-23 80.2 5.3 5.8e-06 26.6 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA08155.1 - 7.5e-17 59.7 4.4 0.14 12.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Orbi_NS3 PF01616.11 EEA08155.1 - 0.035 13.0 0.2 0.066 12.1 0.1 1.4 1 0 0 1 1 1 0 Orbivirus NS3 AA_permease_2 PF13520.1 EEA08155.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Ribosomal_L7Ae PF01248.21 EEA08156.1 - 1e-23 82.6 0.4 1.3e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 EEA08156.1 - 0.009 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Hexapep PF00132.19 EEA08157.1 - 9.6e-10 37.5 20.9 2.2e-06 26.9 3.9 4.5 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA08157.1 - 9.8e-08 31.4 16.8 0.00013 21.3 2.0 3.9 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EEA08157.1 - 0.011 14.3 0.3 0.017 13.7 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase DUF4602 PF15375.1 EEA08158.1 - 6.8e-07 29.4 14.0 1.1e-06 28.7 9.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Ribosomal_L34e PF01199.13 EEA08158.1 - 0.11 12.7 2.4 0.16 12.2 1.1 1.8 1 1 0 1 1 1 0 Ribosomal protein L34e Nop25 PF09805.4 EEA08158.1 - 2.4 8.2 9.7 0.57 10.2 4.1 1.8 1 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) Methyltransf_31 PF13847.1 EEA08159.1 - 3.4e-09 36.4 0.3 3.4e-09 36.4 0.2 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA08159.1 - 4.9e-09 36.7 0.0 2.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EEA08159.1 - 8.9e-08 31.5 0.3 8.9e-08 31.5 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEA08159.1 - 2.3e-05 23.8 0.0 5.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EEA08159.1 - 0.0009 19.6 0.3 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA08159.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA08159.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2_2 PF12756.2 EEA08159.1 - 0.0097 16.0 0.9 0.034 14.2 0.6 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_25 PF13649.1 EEA08159.1 - 0.01 16.1 0.1 0.029 14.7 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEA08159.1 - 0.019 15.4 0.1 0.079 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.12 EEA08159.1 - 0.054 12.5 0.1 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase Phage_tube PF04985.9 EEA08159.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein FII UPF0020 PF01170.13 EEA08159.1 - 0.11 12.0 1.0 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EEA08159.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MIS13 PF08202.6 EEA08159.1 - 0.16 11.0 6.4 0.27 10.2 4.5 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Vasculin PF15337.1 EEA08159.1 - 0.18 12.2 2.5 0.57 10.6 1.7 1.8 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Prefoldin PF02996.12 EEA08159.1 - 0.22 11.1 4.4 0.42 10.2 2.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit zf-HIT PF04438.11 EEA08160.1 - 3.7e-06 26.4 13.0 6.2e-06 25.7 9.0 1.4 1 0 0 1 1 1 1 HIT zinc finger ArfGap PF01412.13 EEA08160.1 - 0.037 13.7 5.0 0.095 12.4 3.5 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf HeH PF12949.2 EEA08160.1 - 0.044 13.3 0.1 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain Copper-fist PF00649.13 EEA08160.1 - 5.3 6.3 9.8 14 4.9 2.6 2.4 1 1 1 2 2 2 0 Copper fist DNA binding domain Snf7 PF03357.16 EEA08161.1 - 8.4e-21 74.0 27.1 1.1e-20 73.7 18.8 1.1 1 0 0 1 1 1 1 Snf7 NAP PF00956.13 EEA08161.1 - 2.8 6.9 12.2 8.1 5.4 8.3 1.9 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) IclR PF01614.13 EEA08161.1 - 3.3 7.4 6.5 0.25 11.0 0.4 2.1 2 1 1 3 3 3 0 Bacterial transcriptional regulator RNA_pol_Rpb1_5 PF04998.12 EEA08162.1 - 2.1 7.5 5.9 3.7 6.7 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 NAD_synthase PF02540.12 EEA08163.1 - 0.092 11.6 1.8 3 6.6 0.1 2.2 2 0 0 2 2 2 0 NAD synthase SNARE_assoc PF09335.6 EEA08164.1 - 9.4e-06 25.8 1.0 9.4e-06 25.8 0.7 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein FoP_duplication PF13865.1 EEA08165.1 - 1.5e-14 54.1 20.6 1.1e-12 48.2 14.3 3.0 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 BSD PF03909.12 EEA08166.1 - 8.5e-18 63.8 0.2 2.4e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 BSD domain zf-DHHC PF01529.15 EEA08167.1 - 7.9e-36 123.0 0.5 7.9e-36 123.0 0.4 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase ACPS PF01648.15 EEA08168.1 - 2.7e-11 43.2 0.1 3.9e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PLAT PF01477.18 EEA08168.1 - 0.025 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 PLAT/LH2 domain DEAD PF00270.24 EEA08170.1 - 3.4e-29 101.5 0.0 1.1e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08170.1 - 3.7e-20 71.5 0.1 8.4e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA08170.1 - 0.004 17.0 0.0 0.022 14.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 EEA08171.1 - 3e-11 43.1 0.2 5.6e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA08171.1 - 4.6e-09 36.8 0.1 1.4e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EEA08171.1 - 8.2e-09 34.9 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EEA08171.1 - 1.4e-08 34.7 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA08171.1 - 4.4e-06 27.1 0.0 8.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA08171.1 - 9.9e-05 21.7 0.1 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA08171.1 - 0.00015 21.2 0.1 0.00023 20.6 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEA08171.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEA08171.1 - 0.00028 19.7 0.0 0.00037 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EEA08171.1 - 0.0036 17.6 0.2 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EEA08171.1 - 0.0037 16.5 0.0 0.0074 15.6 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EEA08171.1 - 0.027 14.9 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEA08171.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EEA08171.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 CPSF_A PF03178.10 EEA08172.1 - 1e-20 74.0 0.5 1.8e-16 60.1 0.1 2.9 3 0 0 3 3 3 2 CPSF A subunit region Brr6_like_C_C PF10104.4 EEA08174.1 - 0.056 12.9 1.2 0.057 12.9 0.1 1.5 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF1385 PF07136.6 EEA08174.1 - 0.061 12.3 0.2 0.064 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Pox_A14 PF05767.7 EEA08174.1 - 0.21 11.5 1.6 0.29 11.1 1.1 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 SUR7 PF06687.7 EEA08174.1 - 0.32 10.5 3.1 0.41 10.1 2.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family ATP-synt_C PF00137.16 EEA08175.1 - 1e-29 102.2 18.1 1.3e-16 60.2 4.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C RINGv PF12906.2 EEA08176.1 - 5e-13 48.8 7.9 8.9e-13 48.0 5.5 1.4 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.21 EEA08176.1 - 1.2e-12 47.6 0.5 1.2e-12 47.6 0.3 2.7 3 0 0 3 3 3 1 FHA domain zf-RING_2 PF13639.1 EEA08176.1 - 0.0067 16.2 7.1 0.012 15.3 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EEA08176.1 - 0.042 13.8 4.1 0.077 12.9 2.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain NIF PF03031.13 EEA08177.1 - 3.7e-16 59.1 0.6 4e-11 42.8 0.0 2.8 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEA08177.1 - 0.00084 19.1 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEA08177.1 - 0.001 19.2 0.1 0.0078 16.3 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.1 EEA08177.1 - 0.052 13.7 0.0 0.32 11.2 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ESCRT-II PF05871.7 EEA08177.1 - 0.65 9.9 3.7 3.8 7.4 0.3 2.5 2 0 0 2 2 2 0 ESCRT-II complex subunit Raptor_N PF14538.1 EEA08178.1 - 0.012 15.5 0.3 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF3900 PF13039.1 EEA08178.1 - 0.023 14.2 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) SIR2 PF02146.12 EEA08178.1 - 0.074 12.7 2.7 0.1 12.3 1.9 1.3 1 1 0 1 1 1 0 Sir2 family DUF2361 PF10153.4 EEA08178.1 - 0.14 12.3 1.2 0.2 11.8 0.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF1272 PF06906.6 EEA08178.1 - 0.14 12.0 1.8 0.25 11.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) LIM PF00412.17 EEA08178.1 - 0.25 11.4 3.5 0.44 10.6 2.4 1.4 1 0 0 1 1 1 0 LIM domain Med27 PF11571.3 EEA08178.1 - 0.56 10.3 6.9 0.99 9.5 0.6 2.2 1 1 1 2 2 2 0 Mediator complex subunit 27 FYVE_2 PF02318.11 EEA08178.1 - 1.2 8.9 5.6 1.9 8.3 3.9 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger zf-C4pol PF14260.1 EEA08178.1 - 3.7 7.6 7.4 1.4e+02 2.5 5.1 2.7 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta TFIID-31kDa PF02291.10 EEA08179.1 - 2.2e-09 37.1 0.0 2.5e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF1931 PF09123.6 EEA08179.1 - 0.015 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Kazal_1 PF00050.16 EEA08180.1 - 5.7e-07 29.4 3.6 1e-06 28.6 2.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EEA08180.1 - 6.8e-07 29.1 1.2 1.5e-06 28.0 0.8 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Enterotoxin_a PF01375.12 EEA08180.1 - 0.046 13.0 1.8 0.075 12.3 1.3 1.3 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain Myb_DNA-binding PF00249.26 EEA08181.1 - 0.00042 20.2 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sad1_UNC PF07738.8 EEA08182.1 - 8.6e-14 51.4 0.5 2.9e-12 46.5 0.2 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Fcf1 PF04900.7 EEA08184.1 - 1.7e-19 69.7 6.3 1.3e-14 54.0 0.0 3.5 2 1 1 3 3 3 2 Fcf1 Vma12 PF11712.3 EEA08184.1 - 0.21 11.2 6.1 0.17 11.5 3.0 1.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Clat_adaptor_s PF01217.15 EEA08187.1 - 1.8e-40 137.9 6.6 2.1e-40 137.7 4.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.19 EEA08188.1 - 7.2e-15 55.6 0.0 2.8e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Exonuclease WD40 PF00400.27 EEA08189.1 - 0.019 14.8 1.2 4.9 7.2 0.5 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat NOSIC PF08060.8 EEA08191.1 - 0.03 14.1 0.7 0.14 12.0 0.5 2.1 1 0 0 1 1 1 0 NOSIC (NUC001) domain Exostosin PF03016.10 EEA08192.1 - 0.00017 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DnaJ PF00226.26 EEA08193.1 - 7.2e-20 70.4 0.8 7.2e-20 70.4 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain Glyco_transf_20 PF00982.16 EEA08194.1 - 5.5e-92 308.7 0.5 1.2e-68 231.7 0.1 2.4 2 1 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEA08194.1 - 7.4e-50 169.0 0.0 1.1e-48 165.2 0.0 2.2 1 1 0 1 1 1 1 Trehalose-phosphatase Helicase_C PF00271.26 EEA08195.1 - 3.8e-21 74.7 0.0 1.2e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA08195.1 - 2.2e-17 63.0 0.0 2.2e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase Apc3 PF12895.2 EEA08196.1 - 0.00022 21.2 5.6 0.02 15.0 0.0 4.1 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF2668 PF10873.3 EEA08196.1 - 0.01 15.9 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Kelch_4 PF13418.1 EEA08197.1 - 5.8e-17 61.1 6.5 0.0046 16.7 0.0 6.6 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EEA08197.1 - 7e-17 60.9 7.6 1.4e-05 24.8 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EEA08197.1 - 2.3e-11 43.5 10.5 0.016 15.3 0.0 8.2 9 0 0 9 9 9 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA08197.1 - 1.8e-07 30.5 29.2 0.12 11.8 0.3 7.7 7 1 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 EEA08197.1 - 1.7e-06 27.5 11.4 0.8 9.5 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EEA08197.1 - 7.2e-06 25.9 13.4 0.79 9.9 0.1 6.6 5 1 1 6 6 6 2 Kelch motif Gtr1_RagA PF04670.7 EEA08198.1 - 3.1e-45 154.1 2.1 3.1e-45 154.1 1.5 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA08198.1 - 1.4e-07 30.9 0.1 1.4e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEA08198.1 - 3.4e-06 26.4 0.0 5.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA08198.1 - 5.4e-06 26.3 0.2 5.4e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEA08198.1 - 0.015 15.8 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EEA08198.1 - 0.016 15.0 3.5 0.22 11.3 2.4 2.7 1 1 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EEA08198.1 - 0.099 11.8 0.0 0.22 10.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EEA08198.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S3Ae PF01015.13 EEA08198.1 - 0.17 11.1 3.0 0.09 12.0 0.2 1.8 2 0 0 2 2 2 0 Ribosomal S3Ae family Utp12 PF04003.7 EEA08199.1 - 0.00067 19.5 1.1 0.0011 18.8 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family CBM_20 PF00686.14 EEA08201.1 - 1.4e-22 79.0 1.2 2.1e-22 78.5 0.8 1.2 1 0 0 1 1 1 1 Starch binding domain LEM PF03020.10 EEA08201.1 - 4.9 6.6 6.2 0.69 9.4 1.4 1.7 2 0 0 2 2 2 0 LEM domain IMCp PF12314.3 EEA08202.1 - 1.4e-18 66.7 25.0 1.4e-18 66.7 17.4 3.3 1 1 2 3 3 3 3 Inner membrane complex protein DUF727 PF05303.7 EEA08203.1 - 0.0061 16.3 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Mus7 PF09462.5 EEA08203.1 - 0.017 13.9 0.0 0.02 13.7 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family DUF2972 PF11186.3 EEA08203.1 - 0.039 13.8 3.1 0.044 13.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) zf-DHHC PF01529.15 EEA08204.1 - 4.4e-38 130.3 4.7 4.4e-38 130.3 3.2 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase TFIIE_beta PF02186.10 EEA08205.1 - 0.063 13.2 0.5 0.15 12.0 0.2 1.8 1 1 0 1 1 1 0 TFIIE beta subunit core domain Sedlin_N PF04628.8 EEA08207.1 - 1.3e-30 105.9 0.0 1.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEA08207.1 - 4.3e-05 23.2 0.0 6.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Sybindin-like family AP-5_subunit_s1 PF15001.1 EEA08210.1 - 0.00054 19.9 0.2 0.0006 19.8 0.1 1.1 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 ENOD40 PF08247.6 EEA08210.1 - 0.089 12.6 1.7 0.24 11.2 1.2 1.7 1 0 0 1 1 1 0 ENOD40 protein DUF2130 PF09903.4 EEA08211.1 - 0.00013 20.8 6.0 0.00013 20.8 4.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2130) Pepsin-I3 PF06394.8 EEA08211.1 - 0.028 14.0 4.4 1.9 8.2 0.1 2.5 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Fzo_mitofusin PF04799.8 EEA08211.1 - 0.25 10.6 10.0 0.029 13.7 2.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF1940 PF09155.5 EEA08211.1 - 2.1 8.1 7.2 7.6 6.3 2.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1940) PhoU PF01895.14 EEA08211.1 - 4.4 7.8 7.1 13 6.3 4.3 2.3 1 1 1 2 2 2 0 PhoU domain Pkinase PF00069.20 EEA08212.1 - 7.2e-60 202.3 0.2 9.1e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08212.1 - 7e-42 143.2 0.0 1.6e-41 142.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA08212.1 - 9.6e-07 28.0 0.0 4.7e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RRM_6 PF14259.1 EEA08213.1 - 9e-19 67.2 0.0 2.2e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA08213.1 - 4.5e-18 64.6 0.8 4.9e-08 32.5 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08213.1 - 2.3e-13 49.7 0.5 2.4e-09 36.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA08213.1 - 0.012 15.4 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif EMP24_GP25L PF01105.19 EEA08214.1 - 5.7e-19 68.5 4.1 1e-18 67.7 2.9 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNB PF00773.14 EEA08215.1 - 2.7e-74 250.3 13.1 2.7e-74 250.3 9.1 3.0 3 1 0 3 3 3 1 RNB domain OB_RNB PF08206.6 EEA08215.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF288 PF03385.12 EEA08216.1 - 0.033 12.6 1.3 0.054 11.9 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF288 Peptidase_S49 PF01343.13 EEA08217.1 - 0.044 13.5 0.1 0.095 12.4 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 Pkinase PF00069.20 EEA08218.1 - 1.6e-58 197.9 0.2 5.8e-58 196.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08218.1 - 3.1e-28 98.5 0.1 2.9e-27 95.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEA08218.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT PF02985.17 EEA08219.1 - 0.0012 18.7 0.2 3.2 8.0 0.1 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EEA08219.1 - 0.19 12.0 0.3 0.97 9.7 0.1 2.4 2 1 0 2 2 2 0 HEAT repeats BRCA2 PF00634.13 EEA08220.1 - 5.8e-22 76.6 7.4 6e-06 25.4 0.1 4.7 4 0 0 4 4 4 4 BRCA2 repeat BRCA-2_OB1 PF09103.5 EEA08220.1 - 2.1e-13 49.9 0.0 9e-13 47.9 0.0 2.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 PAP2 PF01569.16 EEA08221.1 - 8.8e-06 25.4 6.4 8.8e-06 25.4 4.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily Alg14 PF08660.6 EEA08223.1 - 0.18 11.7 2.8 2.8 7.8 0.0 3.0 2 1 1 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like DUF4131 PF13567.1 EEA08223.1 - 0.92 8.8 10.6 0.061 12.7 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF373 PF04123.8 EEA08223.1 - 5.6 5.8 10.7 7.3 5.5 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Histone PF00125.19 EEA08224.1 - 1.6e-13 50.5 0.4 2e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA08224.1 - 0.00035 20.5 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EEA08224.1 - 0.0017 18.2 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEA08224.1 - 0.0071 16.4 0.1 0.0098 16.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EEA08224.1 - 0.0097 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FbpA PF05833.6 EEA08224.1 - 0.023 13.2 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Bromo_TP PF07524.8 EEA08224.1 - 0.033 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Thr_dehydrat_C PF00585.13 EEA08224.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase zf-CCCH PF00642.19 EEA08225.1 - 5.6e-08 32.2 14.8 2.6e-05 23.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EEA08225.1 - 3e-05 23.5 0.0 5.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08225.1 - 7.6e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08225.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 EEA08226.1 - 2e-14 53.0 53.7 3e-09 36.4 6.3 5.3 3 2 3 6 6 6 4 PHD-finger SRP54 PF00448.17 EEA08227.1 - 1.6e-54 184.3 0.5 2.5e-54 183.6 0.1 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EEA08227.1 - 2.6e-12 46.7 22.2 8.2e-10 38.5 6.0 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 EEA08227.1 - 8.7e-06 25.2 3.5 5.5e-05 22.6 1.5 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EEA08227.1 - 2.1e-05 23.4 0.1 5.2e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein SRP54_N PF02881.14 EEA08227.1 - 0.00026 21.0 0.8 0.00069 19.6 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 EEA08227.1 - 0.0027 17.7 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EEA08227.1 - 0.0053 16.4 0.2 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.1 EEA08227.1 - 0.0053 16.3 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEA08227.1 - 0.016 15.1 0.8 0.061 13.2 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EEA08227.1 - 0.02 14.0 0.2 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 EEA08227.1 - 0.034 13.8 0.1 0.089 12.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EEA08227.1 - 0.043 12.9 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Helicase_RecD PF05127.9 EEA08227.1 - 0.069 12.7 0.6 0.22 11.1 0.0 2.1 2 1 0 2 2 2 0 Helicase AAA_22 PF13401.1 EEA08227.1 - 0.075 13.1 0.0 0.31 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.15 EEA08229.1 - 2.9e-29 101.5 0.0 1.7e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EEA08229.1 - 0.052 13.0 0.0 0.23 10.9 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Ribosomal_L12 PF00542.14 EEA08231.1 - 0.0016 18.3 18.1 0.65 10.0 0.3 5.5 3 3 2 5 5 5 3 Ribosomal protein L7/L12 C-terminal domain DUF507 PF04368.8 EEA08233.1 - 0.0015 18.1 0.2 0.0017 18.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF507) ApoC-I PF04691.7 EEA08233.1 - 0.036 13.7 0.5 0.07 12.8 0.3 1.6 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Scm3 PF10384.4 EEA08233.1 - 0.052 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Centromere protein Scm3 Lumazine_bd PF12870.2 EEA08233.1 - 0.054 13.5 0.5 0.066 13.2 0.3 1.2 1 0 0 1 1 1 0 Lumazine-binding domain DUF1433 PF07252.6 EEA08233.1 - 0.076 13.2 1.5 0.14 12.3 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1433) DUF4199 PF13858.1 EEA08233.1 - 0.11 12.3 0.5 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Baculo_PEP_C PF04513.7 EEA08233.1 - 1.7 8.4 8.1 2.8 7.7 5.6 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-LYAR PF08790.6 EEA08239.1 - 0.0081 15.8 1.3 0.027 14.1 0.9 1.9 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Abhydrolase_2 PF02230.11 EEA08241.1 - 6.1e-28 97.7 0.0 9.1e-27 93.9 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEA08241.1 - 8.4e-05 21.8 0.1 0.00039 19.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EEA08241.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EEA08241.1 - 0.003 17.3 0.0 0.0058 16.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S13_N PF08069.7 EEA08241.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Ank_2 PF12796.2 EEA08242.1 - 8.6e-24 83.6 2.2 4.6e-14 52.5 0.3 5.1 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA08242.1 - 3.3e-20 70.8 11.2 5.4e-06 25.9 0.1 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EEA08242.1 - 1.5e-15 57.2 5.7 4.7e-07 30.1 0.1 6.2 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA08242.1 - 2.8e-12 45.6 10.2 0.01 15.9 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EEA08242.1 - 5.9e-10 39.0 7.6 2.8e-06 27.3 0.4 5.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) SIS PF01380.17 EEA08243.1 - 6.5e-40 135.7 0.4 6.2e-22 77.6 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EEA08243.1 - 1.1e-24 86.8 0.2 2e-24 86.0 0.2 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEA08243.1 - 3.8e-19 68.6 0.0 7.5e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EEA08243.1 - 2.9e-14 52.5 1.6 3.7e-12 45.6 0.1 2.6 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 EEA08243.1 - 3.1e-05 22.8 0.4 5.8e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EEA08243.1 - 1.2 8.8 6.3 7.9 6.2 0.1 3.5 3 2 2 5 5 5 0 SIS domain Mannosyl_trans PF05007.8 EEA08244.1 - 7e-54 183.1 33.5 1.5e-53 182.1 23.2 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 EEA08244.1 - 0.0027 17.2 0.3 0.0027 17.2 0.2 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) AMP-binding PF00501.23 EEA08245.1 - 2.4e-90 302.9 0.0 3e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA08245.1 - 6.9e-19 68.5 0.1 1.3e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HCNGP PF07818.8 EEA08245.1 - 0.005 16.8 0.4 0.74 9.8 0.1 2.6 2 0 0 2 2 2 2 HCNGP-like protein WD40 PF00400.27 EEA08246.1 - 1.1e-40 136.0 9.1 8.8e-08 31.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA08246.1 - 2.5e-08 33.8 0.3 0.27 10.9 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEA08246.1 - 0.044 11.9 3.7 0.65 8.0 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Asp PF00026.18 EEA08247.1 - 6.5e-19 68.3 0.7 2e-12 46.9 0.1 3.3 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA08247.1 - 2.4e-18 66.2 0.0 7.3e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EEA08247.1 - 7.6e-14 51.9 0.5 1.6e-13 50.9 0.3 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal EGF PF00008.22 EEA08248.1 - 3.9e-11 42.7 33.9 0.00089 19.1 5.4 3.9 3 1 0 3 3 3 3 EGF-like domain EGF_2 PF07974.8 EEA08248.1 - 3.3e-10 39.9 38.8 0.003 17.6 5.4 4.0 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.2 EEA08248.1 - 9.1e-07 28.5 20.8 0.0054 16.7 0.7 3.9 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_3 PF12947.2 EEA08248.1 - 0.00075 19.4 31.5 0.22 11.5 2.1 3.6 3 0 0 3 3 3 3 EGF domain EGF_alliinase PF04863.8 EEA08248.1 - 0.0016 18.3 4.5 0.0016 18.3 3.1 3.9 2 1 2 4 4 4 1 Alliinase EGF-like domain Laminin_EGF PF00053.19 EEA08248.1 - 0.012 15.5 25.2 0.68 9.9 2.6 3.5 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) Oxidored_q2 PF00420.19 EEA08248.1 - 0.027 14.0 1.0 0.11 12.0 0.2 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4208 PF13907.1 EEA08249.1 - 3.7e-13 49.5 0.1 5.1e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DUF3105 PF11303.3 EEA08249.1 - 0.027 14.3 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) SWIB PF02201.13 EEA08249.1 - 0.055 13.1 0.1 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 SWIB/MDM2 domain MAGUK_N_PEST PF10608.4 EEA08249.1 - 0.1 13.0 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK SNF2_N PF00176.18 EEA08250.1 - 8.5e-71 238.1 2.1 1.5e-70 237.4 1.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EEA08250.1 - 8.8e-21 73.3 6.6 1.2e-10 40.9 0.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EEA08250.1 - 1.9e-15 56.4 0.0 6.6e-15 54.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA08250.1 - 3.5e-06 26.6 0.0 0.00056 19.4 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase PITH PF06201.8 EEA08251.1 - 1.3e-37 128.8 0.1 1.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain DLIC PF05783.6 EEA08254.1 - 5.9e-12 45.0 7.9 8.7e-11 41.1 0.1 2.9 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) AAA_18 PF13238.1 EEA08254.1 - 0.0064 16.7 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA08254.1 - 0.027 15.2 0.1 0.059 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA08254.1 - 0.041 14.0 0.2 0.23 11.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA08254.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TAFII55_N PF04658.8 EEA08255.1 - 1.5e-20 73.3 0.0 6e-20 71.3 0.0 2.0 2 1 0 2 2 2 1 TAFII55 protein conserved region Patatin PF01734.17 EEA08256.1 - 1.4e-12 48.0 0.7 1e-11 45.2 0.5 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Rax2 PF12768.2 EEA08259.1 - 4.2e-05 22.8 0.0 5.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EEA08259.1 - 0.041 13.5 0.4 0.064 12.9 0.3 1.4 1 1 0 1 1 1 0 TMEM154 protein family CoA_binding_3 PF13727.1 EEA08259.1 - 0.086 12.6 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 CoA-binding domain DUF4448 PF14610.1 EEA08259.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EEA08259.1 - 0.15 12.4 0.5 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EEA08259.1 - 0.82 9.7 2.8 2.5 8.2 1.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IncFII_repA PF02387.10 EEA08260.1 - 0.012 14.7 0.4 0.32 10.1 0.1 2.2 2 0 0 2 2 2 0 IncFII RepA protein family FokI_C PF02980.11 EEA08260.1 - 0.024 14.3 0.2 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain PG_binding_2 PF08823.6 EEA08260.1 - 0.035 14.2 0.4 0.44 10.6 0.0 2.7 2 1 0 2 2 2 0 Putative peptidoglycan binding domain PAN_4 PF14295.1 EEA08261.1 - 0.0016 18.0 1.1 0.0044 16.7 0.8 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EEA08261.1 - 0.011 15.6 0.6 0.03 14.1 0.4 1.8 1 0 0 1 1 1 0 PAN-like domain SSP160 PF06933.6 EEA08261.1 - 4 5.3 17.8 5.4 4.8 12.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_11 PF13414.1 EEA08263.1 - 8.3e-08 31.7 17.0 0.011 15.3 0.0 6.8 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 EEA08263.1 - 0.00053 19.6 16.5 0.54 10.3 0.0 8.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA08263.1 - 0.00082 18.8 0.2 0.00082 18.8 0.1 8.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA08263.1 - 0.0011 19.2 0.4 15 6.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA08263.1 - 0.0019 18.5 1.6 2.9 8.5 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA08263.1 - 0.0071 16.9 0.1 0.44 11.2 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA08263.1 - 0.008 16.7 0.2 26 5.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA08263.1 - 0.013 15.4 19.7 7.2 6.6 0.0 8.8 8 3 2 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA08263.1 - 0.029 14.1 5.8 6.2 6.8 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA08263.1 - 0.031 14.0 17.6 0.63 9.9 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat RRM_1 PF00076.17 EEA08264.1 - 3.6e-38 129.0 0.0 1.2e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08264.1 - 3e-27 94.3 0.0 1.4e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08264.1 - 2e-12 46.7 0.0 1.8e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEA08264.1 - 7.6e-05 22.3 0.2 0.018 14.7 0.0 2.4 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EEA08264.1 - 0.00017 21.3 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif AP2 PF00847.15 EEA08265.1 - 1.2e-09 38.1 2.8 1.2e-09 38.1 2.0 1.7 2 0 0 2 2 2 1 AP2 domain TSP_1 PF00090.14 EEA08266.1 - 7.9e-09 35.4 63.8 1e-07 31.9 6.0 7.1 5 2 0 5 5 5 4 Thrombospondin type 1 domain TSP_1 PF00090.14 EEA08267.1 - 3.8e-27 94.1 92.6 3.3e-08 33.5 6.8 8.5 9 0 0 9 9 9 6 Thrombospondin type 1 domain PCI PF01399.22 EEA08269.1 - 3.8e-10 40.0 0.2 3.8e-10 40.0 0.2 2.9 3 2 0 3 3 3 1 PCI domain FHA PF00498.21 EEA08270.1 - 1.8e-14 53.5 0.2 4.3e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain F_actin_cap_B PF01115.12 EEA08271.1 - 9.5e-20 70.8 7.1 3.9e-19 68.7 4.9 2.0 1 1 0 1 1 1 1 F-actin capping protein, beta subunit Dus PF01207.12 EEA08273.1 - 5e-68 229.2 0.0 7e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EEA08273.1 - 4.5e-07 29.3 0.0 6.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EEA08273.1 - 0.0052 15.8 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EEA08273.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Oxidored_FMN PF00724.15 EEA08273.1 - 0.049 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family DHO_dh PF01180.16 EEA08273.1 - 0.051 12.5 0.0 0.74 8.7 0.0 2.2 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1722 PF08349.6 EEA08273.1 - 0.073 12.9 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) NMO PF03060.10 EEA08273.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ERCC4 PF02732.10 EEA08274.1 - 2.9e-21 75.7 4.6 1.3e-19 70.3 0.0 2.7 2 1 0 2 2 2 2 ERCC4 domain HHH_8 PF14716.1 EEA08274.1 - 0.03 14.4 0.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sld5 PF05916.6 EEA08275.1 - 2.5e-10 40.5 0.1 3.5e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein SIP1 PF04938.7 EEA08276.1 - 0.086 12.1 0.9 0.11 11.7 0.6 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) AAA PF00004.24 EEA08277.1 - 5.4e-41 139.8 0.0 1.2e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEA08277.1 - 3.9e-13 49.0 0.0 1.4e-12 47.2 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EEA08277.1 - 3e-12 46.2 0.8 6.8e-12 45.0 0.5 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 EEA08277.1 - 4.7e-06 25.8 0.0 8.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEA08277.1 - 1.1e-05 25.3 0.0 3.9e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EEA08277.1 - 3.1e-05 24.7 0.1 8.6e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA08277.1 - 3.8e-05 23.8 1.2 0.016 15.3 0.1 2.7 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 EEA08277.1 - 5.4e-05 23.0 1.1 0.00017 21.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EEA08277.1 - 5.8e-05 22.8 0.0 0.00015 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEA08277.1 - 0.0001 21.8 0.7 0.056 12.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA08277.1 - 0.00014 21.7 0.1 0.00059 19.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA08277.1 - 0.00015 21.8 0.1 0.00087 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEA08277.1 - 0.00022 20.6 0.0 0.00077 18.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein KaiC PF06745.8 EEA08277.1 - 0.00035 19.7 0.2 0.4 9.7 0.0 2.5 1 1 1 2 2 2 2 KaiC Bac_DnaA PF00308.13 EEA08277.1 - 0.00068 19.3 0.1 0.0094 15.6 0.1 2.3 1 1 0 1 1 1 1 Bacterial dnaA protein TIP49 PF06068.8 EEA08277.1 - 0.0012 17.6 0.0 0.0031 16.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EEA08277.1 - 0.0016 18.7 1.3 0.0038 17.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA08277.1 - 0.0018 18.4 0.1 0.0082 16.3 0.0 2.3 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 EEA08277.1 - 0.0039 16.9 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain ResIII PF04851.10 EEA08277.1 - 0.0045 16.8 0.2 0.076 12.8 0.0 2.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EEA08277.1 - 0.0047 16.5 1.0 0.0091 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEA08277.1 - 0.0098 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 EEA08277.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EEA08277.1 - 0.016 14.4 1.3 0.019 14.1 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EEA08277.1 - 0.024 13.8 0.0 0.055 12.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEA08277.1 - 0.037 13.7 1.0 0.79 9.3 0.0 2.8 2 1 1 3 3 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 EEA08277.1 - 0.046 12.5 2.2 0.1 11.4 0.4 2.4 2 1 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EEA08277.1 - 0.059 13.0 0.1 0.71 9.5 0.0 2.3 1 1 0 2 2 2 0 NACHT domain WWE PF02825.15 EEA08277.1 - 0.08 12.3 1.1 1.8 8.0 0.1 2.5 2 0 0 2 2 2 0 WWE domain GPI2 PF06432.6 EEA08278.1 - 3.3e-30 105.3 20.4 4.2e-29 101.7 14.1 1.9 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Myb_DNA-binding PF00249.26 EEA08280.1 - 5.6e-07 29.5 0.1 1.6e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA08280.1 - 0.002 18.1 1.7 0.0091 16.0 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain GBP PF02263.14 EEA08281.1 - 4.6e-20 71.7 0.9 4.6e-20 71.7 0.7 2.3 1 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EEA08281.1 - 0.00042 20.2 1.3 0.0011 18.9 0.2 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase eIF-5a PF01287.15 EEA08281.1 - 0.004 17.0 0.0 0.004 17.0 0.0 3.6 4 0 0 4 4 4 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RRM_1 PF00076.17 EEA08282.1 - 1e-38 130.8 0.4 5.5e-19 67.5 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08282.1 - 1.8e-22 79.0 0.0 3.1e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08282.1 - 2.3e-22 78.6 0.1 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 EEA08282.1 - 0.0029 17.5 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EEA08282.1 - 0.0077 15.7 0.6 0.96 9.0 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Ank_2 PF12796.2 EEA08283.1 - 4.2e-51 171.2 0.1 2.1e-22 79.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA08283.1 - 8.2e-50 164.2 0.3 2.3e-08 33.4 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EEA08283.1 - 8.9e-38 128.0 6.8 1.9e-12 47.3 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA08283.1 - 2e-34 114.1 3.5 2.1e-06 27.3 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EEA08283.1 - 2.9e-33 113.1 0.8 4e-09 36.4 0.1 5.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) RNA_GG_bind PF10258.4 EEA08283.1 - 2.4e-28 97.6 0.2 4.5e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain Mg_trans_NIPA PF05653.9 EEA08285.1 - 9e-13 47.8 20.0 1.3e-12 47.3 13.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EEA08285.1 - 0.0025 17.8 12.4 0.0025 17.8 8.6 3.3 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EEA08285.1 - 0.018 15.2 5.8 0.018 15.2 4.0 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter IncA PF04156.9 EEA08285.1 - 0.042 13.4 0.1 0.042 13.4 0.1 3.2 3 1 0 3 3 3 0 IncA protein DUF2157 PF09925.4 EEA08285.1 - 3.2 7.3 10.6 0.44 10.1 2.0 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Pico_P2B PF01552.12 EEA08286.1 - 0.025 14.7 0.0 0.025 14.7 0.0 5.4 5 0 0 5 5 5 0 Picornavirus 2B protein Cullin PF00888.17 EEA08286.1 - 0.23 9.9 7.5 1.3 7.5 0.0 3.3 4 0 0 4 4 4 0 Cullin family zf-Tim10_DDP PF02953.10 EEA08287.1 - 4.5e-15 54.6 2.5 5.5e-15 54.4 1.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NCD3G PF07562.9 EEA08287.1 - 0.011 15.4 1.7 0.015 15.0 1.2 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Helicase_C PF00271.26 EEA08290.1 - 8e-22 76.9 0.0 3.9e-20 71.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA08290.1 - 4.3e-18 65.3 0.0 1.7e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 EEA08290.1 - 2e-08 33.8 0.0 5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RQC PF09382.5 EEA08290.1 - 0.00035 20.2 0.1 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 RQC domain DNA_pol_B PF00136.16 EEA08291.1 - 6e-130 434.1 0.4 9.3e-130 433.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEA08291.1 - 5.7e-67 225.8 8.3 9.7e-67 225.1 5.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEA08291.1 - 5.2e-19 68.0 12.6 1.4e-18 66.6 8.7 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.6 EEA08291.1 - 6.7 6.8 9.9 0.49 10.4 0.4 2.9 2 0 0 2 2 2 0 RING-like domain ProRS-C_1 PF09180.6 EEA08292.1 - 1.8e-23 82.1 0.3 4.9e-23 80.8 0.2 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EEA08292.1 - 3.7e-20 72.2 0.6 8.4e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 EEA08292.1 - 4.4e-20 71.7 0.0 1e-19 70.5 0.0 1.6 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 EEA08292.1 - 2.4e-18 65.8 0.3 1.1e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain Mannitol_dh PF01232.18 EEA08293.1 - 0.16 11.9 2.1 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain RRM_1 PF00076.17 EEA08295.1 - 5.4e-09 35.5 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08295.1 - 0.00019 21.3 0.0 0.00053 19.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08295.1 - 0.00036 20.3 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec66 PF09802.4 EEA08296.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Claudin_2 PF13903.1 EEA08296.1 - 0.063 12.9 9.6 0.16 11.6 6.6 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Adeno_E3_CR2 PF02439.10 EEA08296.1 - 0.084 12.4 0.7 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 VPEP PF07589.6 EEA08296.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 PEP-CTERM motif SUR7 PF06687.7 EEA08296.1 - 1.8 8.0 9.9 3 7.3 6.9 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF3180 PF11377.3 EEA08296.1 - 2.1 8.2 5.5 9.1 6.1 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) FtsX PF02687.16 EEA08296.1 - 4.5 7.0 12.9 13 5.5 5.7 2.5 2 1 0 2 2 2 0 FtsX-like permease family AAA PF00004.24 EEA08297.1 - 4.4e-40 136.9 0.0 8.3e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA08297.1 - 8.5e-07 29.1 0.1 0.00011 22.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEA08297.1 - 6e-06 26.0 0.0 2.4e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA08297.1 - 0.00011 22.2 0.1 0.0011 18.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA08297.1 - 0.00011 22.9 0.1 0.00025 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEA08297.1 - 0.00078 19.3 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEA08297.1 - 0.00092 18.9 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EEA08297.1 - 0.0012 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEA08297.1 - 0.0078 16.0 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EEA08297.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEA08297.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA08297.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EEA08297.1 - 0.025 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA08297.1 - 0.033 14.0 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEA08297.1 - 0.034 13.5 0.0 0.9 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEA08297.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EEA08297.1 - 0.043 12.5 0.0 0.078 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 EEA08297.1 - 0.044 13.3 0.1 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA08297.1 - 0.046 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EEA08297.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.1 EEA08297.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEA08297.1 - 0.1 11.7 0.1 1.1 8.3 0.0 2.5 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 EEA08297.1 - 0.13 11.9 0.0 13 5.4 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase BLOC1_2 PF10046.4 EEA08297.1 - 0.14 12.3 0.2 0.62 10.2 0.0 2.2 3 0 0 3 3 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sigma54_activat PF00158.21 EEA08297.1 - 0.15 11.5 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EEA08297.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Myosin_head PF00063.16 EEA08298.1 - 1.5e-202 674.3 0.5 4.6e-202 672.7 0.3 1.9 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 EEA08298.1 - 8.1e-08 31.2 8.0 0.014 14.9 0.2 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif FtsK_SpoIIIE PF01580.13 EEA08298.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EEA08298.1 - 0.031 14.4 2.5 0.61 10.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.14 EEA08298.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain CALCOCO1 PF07888.6 EEA08298.1 - 0.2 9.8 46.8 0.11 10.7 7.1 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_19 PF13245.1 EEA08298.1 - 0.38 10.5 0.0 1.1 9.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain His_Phos_1 PF00300.17 EEA08299.1 - 1.3e-17 64.3 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S7 PF00177.16 EEA08300.1 - 1.9e-40 137.8 0.2 2.3e-40 137.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TRAPPC-Trs85 PF12739.2 EEA08301.1 - 3.4e-74 249.9 3.7 6.2e-74 249.1 2.6 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 EEA08301.1 - 0.026 13.7 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP IncA PF04156.9 EEA08302.1 - 0.0062 16.1 44.7 0.16 11.5 12.1 3.4 1 1 2 3 3 3 2 IncA protein DUF4201 PF13870.1 EEA08302.1 - 0.66 9.3 52.1 0.1 12.0 26.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) FlxA PF14282.1 EEA08302.1 - 1.5 8.7 60.3 0.044 13.7 14.1 3.9 2 1 1 4 4 4 0 FlxA-like protein AAA_27 PF13514.1 EEA08302.1 - 2.9 5.4 27.0 1.3 6.6 15.0 2.1 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.4 EEA08302.1 - 4.8 6.0 42.5 2.6 6.9 16.4 2.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PseudoU_synth_2 PF00849.17 EEA08303.1 - 0.00032 20.5 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 RNA pseudouridylate synthase 2-oxoacid_dh PF00198.18 EEA08305.1 - 7.9e-73 244.5 0.0 1.2e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEA08305.1 - 1.1e-15 57.0 1.7 1.4e-15 56.6 0.6 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.1 EEA08305.1 - 0.015 15.6 0.4 0.85 9.9 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EEA08305.1 - 0.016 14.8 1.6 0.16 11.6 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.14 EEA08305.1 - 0.028 14.0 0.4 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Glycine cleavage H-protein ATP_bind_1 PF03029.12 EEA08306.1 - 6.9e-77 258.1 0.1 7.8e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EEA08306.1 - 1.3e-05 25.9 0.0 2.9e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA08306.1 - 0.0045 17.2 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Orthopox_A47 PF06334.6 EEA08306.1 - 0.0079 15.3 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Orthopoxvirus A47 protein AAA_19 PF13245.1 EEA08306.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EEA08306.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA08306.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEA08306.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEA08306.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EEA08306.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EEA08306.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CS PF04969.11 EEA08307.1 - 0.00023 21.6 5.1 0.00046 20.6 3.5 1.7 1 1 0 1 1 1 1 CS domain CDC37_N PF03234.9 EEA08307.1 - 0.036 14.3 1.4 0.036 14.3 1.0 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1964 PF09244.5 EEA08307.1 - 0.16 12.2 0.3 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) Mo25 PF08569.6 EEA08309.1 - 1.3e-65 221.6 21.2 1.3e-65 221.6 14.7 2.3 1 1 0 2 2 2 2 Mo25-like RabGAP-TBC PF00566.13 EEA08310.1 - 7.7e-53 179.1 1.1 1.2e-52 178.5 0.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.18 EEA08311.1 - 2.6e-109 365.0 2.4 2.6e-109 365.0 1.7 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF885 PF05960.6 EEA08311.1 - 0.63 9.1 15.6 0.045 12.9 4.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) Apolipoprotein PF01442.13 EEA08311.1 - 3.2 7.2 9.8 1.3 8.4 0.4 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Metallophos PF00149.23 EEA08312.1 - 9.4e-39 132.8 0.5 9.4e-39 132.8 0.3 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Ribosomal_L16 PF00252.13 EEA08313.1 - 7.3e-32 109.9 0.2 9.1e-32 109.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e rve PF00665.21 EEA08313.1 - 0.08 13.0 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain UQ_con PF00179.21 EEA08314.1 - 1.7e-40 137.7 0.3 2e-40 137.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA08314.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 RWD domain EF-hand_7 PF13499.1 EEA08316.1 - 0.0017 18.4 0.2 0.029 14.4 0.1 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA08316.1 - 0.0022 17.1 0.0 0.053 12.8 0.0 2.8 2 0 0 2 2 2 1 EF hand DUF416 PF04222.7 EEA08316.1 - 0.0031 16.6 1.1 0.62 9.1 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF416) EF-hand_6 PF13405.1 EEA08316.1 - 0.0052 16.5 0.3 0.056 13.3 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain FH2 PF02181.18 EEA08318.1 - 4e-79 266.1 0.4 7.1e-79 265.3 0.3 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_12 PF13424.1 EEA08318.1 - 2e-13 50.0 1.0 6e-07 29.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EEA08318.1 - 4.4e-06 26.4 0.0 1.3 9.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA08318.1 - 0.0018 17.8 0.1 0.23 11.1 0.0 3.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEA08318.1 - 0.054 13.4 6.7 28 4.9 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA08318.1 - 0.46 10.1 9.7 2.5 7.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4167 PF13763.1 EEA08318.1 - 8.8 6.4 7.9 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Ndc80_HEC PF03801.8 EEA08319.1 - 2e-34 118.3 0.2 2e-34 118.3 0.1 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family DUF4322 PF14210.1 EEA08319.1 - 0.056 12.9 1.9 0.25 10.8 1.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) CIAPIN1 PF05093.8 EEA08320.1 - 8e-24 83.6 9.9 1.6e-23 82.6 6.9 1.5 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Hydrolase_4 PF12146.3 EEA08323.1 - 4.6e-07 29.5 0.0 6.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_5 PF12695.2 EEA08323.1 - 6.5e-05 22.7 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA08323.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1668 PF07893.8 EEA08323.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) NT-C2 PF10358.4 EEA08324.1 - 1.4e-27 95.9 2.8 5.6e-27 93.9 0.0 2.9 3 0 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2730 PF10805.3 EEA08324.1 - 0.23 11.2 10.5 1.5 8.6 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF788 PF05620.6 EEA08325.1 - 3e-18 66.2 14.9 3.5e-17 62.7 10.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF788) Cullin PF00888.17 EEA08327.1 - 2.5e-25 89.1 19.1 8.8e-24 83.9 13.2 2.9 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEA08327.1 - 0.00025 20.8 6.7 0.0011 18.6 4.6 2.2 1 1 0 1 1 1 1 Cullin protein neddylation domain PDEase_I PF00233.14 EEA08329.1 - 9e-36 123.8 2.1 3.9e-35 121.7 1.4 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EEA08329.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 HD domain Rod_cone_degen PF15201.1 EEA08331.1 - 0.005 16.6 0.6 3.6 7.5 0.1 3.6 3 0 0 3 3 3 1 Progressive rod-cone degeneration IKKbetaNEMObind PF12179.3 EEA08331.1 - 0.2 11.4 0.7 25 4.7 0.0 2.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain zf-DHHC PF01529.15 EEA08334.1 - 3.7e-35 120.8 8.6 3.7e-35 120.8 6.0 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.4 EEA08334.1 - 0.027 13.0 0.1 0.027 13.0 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UCH PF00443.24 EEA08335.1 - 1.6e-48 165.1 3.5 2.8e-48 164.3 2.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA08335.1 - 3.7e-24 85.6 0.2 1.9e-18 66.9 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA08335.1 - 4.3e-11 42.7 0.0 2.5e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EEA08335.1 - 0.00089 19.0 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Myosin_head PF00063.16 EEA08336.1 - 8.4e-180 599.1 0.6 8.4e-180 599.1 0.4 2.4 2 1 0 2 2 2 1 Myosin head (motor domain) WD40 PF00400.27 EEA08336.1 - 3.6e-15 55.1 2.7 0.00019 21.2 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat IQ PF00612.22 EEA08336.1 - 6.1e-14 50.2 24.4 0.0038 16.7 0.1 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif RILP PF11461.3 EEA08336.1 - 0.00027 21.0 0.8 0.00083 19.4 0.5 1.8 1 0 0 1 1 1 1 Rab interacting lysosomal protein TMF_TATA_bd PF12325.3 EEA08336.1 - 0.044 13.5 6.9 0.1 12.3 4.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Miro PF08477.8 EEA08336.1 - 0.048 14.1 2.4 0.29 11.6 0.0 3.5 5 0 0 5 5 5 0 Miro-like protein Rab5-bind PF09311.6 EEA08336.1 - 0.12 12.2 7.0 0.21 11.4 4.8 1.4 1 0 0 1 1 1 0 Rabaptin-like protein AAA_16 PF13191.1 EEA08336.1 - 0.17 11.8 0.7 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain IncA PF04156.9 EEA08336.1 - 0.33 10.5 11.9 0.71 9.4 8.2 1.5 1 0 0 1 1 1 0 IncA protein Gln-synt_C PF00120.19 EEA08337.1 - 1.3e-85 286.7 0.1 2.2e-85 285.9 0.0 1.4 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEA08337.1 - 4.4e-20 71.0 0.3 1e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RNA_pol_Rpc34 PF05158.7 EEA08338.1 - 2.9e-43 148.2 11.7 2e-40 139.0 8.1 2.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EEA08338.1 - 0.00068 19.4 0.4 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Ank PF00023.25 EEA08339.1 - 8.7e-32 107.3 5.3 5.5e-08 32.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EEA08339.1 - 3.8e-30 104.0 4.9 3.8e-18 65.6 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA08339.1 - 7.4e-24 83.2 5.4 1.2e-07 31.6 0.1 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA08339.1 - 2.1e-23 82.2 5.2 2e-08 34.5 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA08339.1 - 7.3e-21 72.1 5.1 0.00042 20.2 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat HTH_24 PF13412.1 EEA08339.1 - 0.07 12.5 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PIG-H PF10181.4 EEA08340.1 - 2.5e-09 36.6 3.8 2.5e-09 36.6 2.6 2.4 2 1 1 3 3 3 1 GPI-GlcNAc transferase complex, PIG-H component DUF2512 PF10710.4 EEA08340.1 - 0.085 12.3 13.0 0.13 11.7 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) WD40 PF00400.27 EEA08341.1 - 3.1e-31 106.1 8.6 2.2e-07 30.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA08341.1 - 0.00011 21.9 0.2 1.3 8.7 0.0 3.2 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A KOW PF00467.24 EEA08342.1 - 1.8e-05 24.2 1.3 3.7e-05 23.2 0.9 1.6 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.9 EEA08342.1 - 0.017 14.2 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase Ribosomal_S8e PF01201.17 EEA08343.1 - 1.4e-50 170.8 0.3 1.7e-50 170.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF3143 PF11341.3 EEA08344.1 - 0.18 11.7 1.0 0.31 10.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) Glyco_transf_34 PF05637.7 EEA08345.1 - 2.7e-05 23.8 6.7 0.00087 18.8 1.6 3.3 1 1 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Spt5-NGN PF03439.8 EEA08346.1 - 2.1e-18 65.8 0.1 8.3e-18 63.9 0.0 2.2 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EEA08346.1 - 3.7e-13 48.6 0.3 0.19 11.5 0.0 6.2 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.3 EEA08346.1 - 8.4e-06 26.3 8.9 8.4e-06 26.3 6.2 2.0 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.17 EEA08347.1 - 1.4e-61 206.5 0.3 2.1e-61 206.0 0.2 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA08347.1 - 1e-19 71.1 0.0 1.7e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA08347.1 - 4e-16 58.7 0.1 5.6e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA08347.1 - 3e-10 39.6 0.6 3.9e-10 39.2 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA08347.1 - 9.1e-05 22.3 0.2 0.00015 21.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA08347.1 - 9.6e-05 21.8 0.1 0.0003 20.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEA08347.1 - 0.0055 15.9 0.1 0.032 13.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EEA08347.1 - 0.019 14.6 1.7 0.22 11.2 1.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EEA08347.1 - 0.038 12.9 0.5 0.15 11.0 0.0 2.0 2 1 1 3 3 3 0 Septin AAA PF00004.24 EEA08347.1 - 0.086 13.0 0.0 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3449 PF11931.3 EEA08349.1 - 5e-68 228.5 1.4 5e-68 228.5 1.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EEA08349.1 - 5.4e-05 22.6 0.2 0.00017 21.0 0.1 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EEA08349.1 - 0.00023 21.2 0.9 0.28 11.4 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Metalloenzyme PF01676.13 EEA08349.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.4 1 1 0 1 1 1 0 Metalloenzyme superfamily zf-C2H2_jaz PF12171.3 EEA08349.1 - 0.2 11.8 3.6 4.1 7.6 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rft-1 PF04506.8 EEA08350.1 - 6.6e-25 87.4 41.9 1.3e-24 86.5 29.1 1.4 1 1 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.1 EEA08350.1 - 2.3 7.5 33.3 0.017 14.5 12.3 4.1 2 2 1 3 3 3 0 Polysaccharide biosynthesis protein SAC3_GANP PF03399.11 EEA08351.1 - 1.4e-42 145.5 7.0 1.4e-42 145.5 4.9 2.0 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ABC_membrane PF00664.18 EEA08352.1 - 2.6e-66 223.8 39.7 3.9e-36 124.8 9.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA08352.1 - 4.9e-48 162.9 0.0 6.5e-33 113.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA08352.1 - 3.4e-10 39.5 0.0 2.4e-06 26.9 1.3 4.1 3 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA08352.1 - 2e-08 35.0 0.1 0.0065 17.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEA08352.1 - 4.8e-07 30.1 0.1 0.03 14.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EEA08352.1 - 6.7e-07 28.6 0.0 0.011 14.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EEA08352.1 - 3e-05 24.1 10.7 0.00015 21.8 4.1 5.5 4 1 1 5 5 4 2 AAA domain Zeta_toxin PF06414.7 EEA08352.1 - 3.3e-05 23.0 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EEA08352.1 - 9.6e-05 22.0 0.0 0.44 10.0 0.0 2.9 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EEA08352.1 - 0.00024 21.1 1.9 0.54 10.2 0.3 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 EEA08352.1 - 0.00034 20.8 0.1 0.62 10.2 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EEA08352.1 - 0.00055 18.6 0.2 0.0015 17.1 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EEA08352.1 - 0.00075 18.9 1.8 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA08352.1 - 0.001 19.2 0.1 1.7 8.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEA08352.1 - 0.0022 16.8 0.1 0.18 10.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain tRNA_lig_kinase PF08303.6 EEA08352.1 - 0.0039 17.0 0.3 1.9 8.3 0.0 3.2 3 0 0 3 3 3 1 tRNA ligase kinase domain MobB PF03205.9 EEA08352.1 - 0.0053 16.4 0.4 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EEA08352.1 - 0.01 15.7 0.0 0.85 9.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EEA08352.1 - 0.012 15.9 8.7 0.18 12.1 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EEA08352.1 - 0.012 15.5 0.4 5.5 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA08352.1 - 0.023 14.5 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEA08352.1 - 0.025 14.2 0.0 9.8 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEA08352.1 - 0.027 14.6 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EEA08352.1 - 0.053 14.0 0.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ATP-synt_ab PF00006.20 EEA08352.1 - 0.07 12.6 0.2 13 5.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EEA08352.1 - 0.14 11.5 0.1 16 4.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3265 PF11665.3 EEA08352.1 - 2.6 7.9 7.8 8.2 6.3 0.1 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3265) RRM_1 PF00076.17 EEA08353.1 - 7.5e-63 208.1 2.1 9.2e-15 54.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08353.1 - 7.9e-56 185.9 0.3 4.6e-13 48.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08353.1 - 5.6e-38 128.5 0.4 3.4e-07 30.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_T4_C PF04490.7 EEA08353.1 - 7.1 6.3 9.3 2.7 7.7 0.0 4.0 3 2 2 5 5 5 0 Poxvirus T4 protein, C terminus SNARE_assoc PF09335.6 EEA08355.1 - 2.2e-13 50.4 5.6 2.2e-13 50.4 3.9 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein SF3b1 PF08920.5 EEA08356.1 - 1.6e-28 99.5 1.4 3e-28 98.6 1.0 1.4 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EEA08356.1 - 6.7e-15 55.1 0.1 0.071 13.3 0.0 7.9 5 3 3 8 8 8 4 HEAT repeats HEAT PF02985.17 EEA08356.1 - 1.7e-14 52.4 7.7 0.025 14.6 0.0 9.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 EEA08356.1 - 8.9e-11 41.9 0.0 0.081 13.4 0.0 7.9 9 0 0 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA08356.1 - 8.8e-05 22.8 0.7 0.18 12.2 0.0 5.1 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EEA08356.1 - 0.0089 15.3 2.7 7.2 5.8 0.4 4.2 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.18 EEA08356.1 - 0.043 13.6 2.5 92 3.0 0.0 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EEA08356.1 - 0.13 11.2 5.5 1.7 7.5 0.1 3.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Tubulin PF00091.20 EEA08357.1 - 2.3e-71 240.0 0.0 3.7e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA08357.1 - 1.4e-47 160.8 0.1 2.2e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEA08357.1 - 4.3e-05 23.5 0.0 9.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEA08357.1 - 0.041 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain RRM_1 PF00076.17 EEA08358.1 - 3.1e-06 26.7 0.1 9.1e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08358.1 - 3.3e-05 23.6 0.1 7.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08358.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EEA08358.1 - 1.8 8.3 8.2 3.4 7.4 5.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-B_box PF00643.19 EEA08360.1 - 1.7e-05 24.6 29.2 0.00043 20.1 6.0 3.3 3 0 0 3 3 3 2 B-box zinc finger CPW_WPC PF09717.5 EEA08362.1 - 0.03 14.9 2.8 0.03 14.9 2.0 4.6 4 2 2 6 6 6 0 Plasmodium falciparum domain of unknown function (CPW_WPC) DEAD PF00270.24 EEA08363.1 - 2.3e-44 150.8 0.0 7.2e-44 149.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08363.1 - 2.3e-23 81.8 0.0 1.4e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEA08363.1 - 2.7e-06 26.0 2.9 0.00082 17.8 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1253) ResIII PF04851.10 EEA08363.1 - 0.00036 20.4 0.0 0.0023 17.8 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEA08363.1 - 0.016 15.1 0.0 0.13 12.2 0.0 2.3 2 2 0 2 2 2 0 Helicase C-terminal domain AAA_22 PF13401.1 EEA08363.1 - 0.059 13.5 2.2 0.55 10.3 0.1 3.2 4 0 0 4 4 4 0 AAA domain Imm26 PF15572.1 EEA08363.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 26 HIT PF01230.18 EEA08364.1 - 1.5e-24 86.3 0.0 1.9e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEA08364.1 - 2.4e-08 34.1 0.0 4.2e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MAPKK1_Int PF08923.5 EEA08365.1 - 0.0026 17.3 1.0 0.0033 17.0 0.7 1.2 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Peptidase_S8 PF00082.17 EEA08366.1 - 4.3e-49 167.1 2.4 7.3e-49 166.4 1.7 1.4 1 0 0 1 1 1 1 Subtilase family Aminotran_5 PF00266.14 EEA08366.1 - 0.12 11.0 0.1 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Prp19 PF08606.6 EEA08367.1 - 1.2e-31 108.2 1.0 2.5e-31 107.2 0.7 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EEA08367.1 - 8.9e-07 28.7 0.0 3.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 EEA08367.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.27 EEA08367.1 - 0.01 15.7 8.8 0.24 11.3 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Mo25 PF08569.6 EEA08367.1 - 0.025 13.6 1.6 0.071 12.1 0.2 2.0 2 0 0 2 2 2 0 Mo25-like Cas6 PF09559.5 EEA08367.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Cas6 Crispr DUF4463 PF14703.1 EEA08367.1 - 0.099 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) DEAD PF00270.24 EEA08368.1 - 5.9e-43 146.2 0.0 1.3e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08368.1 - 1.3e-22 79.4 0.8 4.5e-22 77.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.7 EEA08368.1 - 4.7e-10 39.3 0.1 1.9e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.10 EEA08368.1 - 3.1e-05 23.8 0.3 0.00014 21.7 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Chordopox_G2 PF05796.7 EEA08368.1 - 0.0026 16.9 0.3 0.0058 15.7 0.2 1.5 1 0 0 1 1 1 1 Chordopoxvirus protein G2 CMS1 PF14617.1 EEA08368.1 - 0.014 14.5 0.4 0.033 13.2 0.3 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERM PF00769.14 EEA08369.1 - 0.0035 16.9 13.7 0.0035 16.9 9.5 2.6 3 0 0 3 3 3 2 Ezrin/radixin/moesin family Tropomyosin PF00261.15 EEA08369.1 - 0.0044 16.1 11.2 0.0044 16.1 7.7 3.6 1 1 2 3 3 3 2 Tropomyosin DUF972 PF06156.8 EEA08369.1 - 1.8 8.9 38.2 2.1 8.7 4.2 4.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EEA08369.1 - 3.1 6.8 14.5 1.5 7.9 0.4 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Peptidase_C1 PF00112.18 EEA08370.1 - 8.1e-68 228.5 2.2 8.1e-68 228.5 1.6 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EEA08370.1 - 2.6e-13 50.0 9.9 2.6e-13 50.0 6.9 2.6 3 0 0 3 3 3 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EEA08370.1 - 1.1e-08 34.0 5.6 1.6e-05 23.6 0.1 2.6 2 1 0 3 3 3 2 Peptidase C1-like family DUF1510 PF07423.6 EEA08370.1 - 0.0043 16.4 0.4 0.0065 15.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_C39_2 PF13529.1 EEA08370.1 - 0.0051 17.1 0.8 0.016 15.5 0.0 2.3 3 0 0 3 3 3 1 Peptidase_C39 like family DUF3328 PF11807.3 EEA08370.1 - 0.0068 16.1 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Wzy_C PF04932.10 EEA08370.1 - 0.0074 16.0 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 O-Antigen ligase Spore_III_AF PF09581.5 EEA08370.1 - 0.026 14.4 1.2 0.076 12.8 0.5 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) ABC2_membrane_3 PF12698.2 EEA08370.1 - 0.04 12.9 0.1 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2140 PF09911.4 EEA08370.1 - 0.086 12.0 1.9 0.15 11.2 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) CRT-like PF08627.5 EEA08371.1 - 4.8e-09 36.2 5.2 4.8e-09 36.2 3.6 3.1 4 0 0 4 4 4 1 CRT-like UAA PF08449.6 EEA08371.1 - 0.00014 20.8 28.5 0.00051 19.0 19.8 1.7 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 EEA08371.1 - 0.00015 20.7 15.6 0.00016 20.6 7.6 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEA08371.1 - 0.00045 20.2 9.2 0.00045 20.2 6.4 3.8 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 EEA08371.1 - 0.31 10.6 27.6 0.95 9.1 7.7 3.4 2 2 0 2 2 2 0 Triose-phosphate Transporter family DUF2371 PF10177.4 EEA08371.1 - 0.79 9.6 7.3 0.081 12.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Acylphosphatase PF00708.13 EEA08372.1 - 4.9e-23 81.0 0.0 5.4e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Baculo_11_kDa PF06143.6 EEA08372.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Phage_holin_6 PF10746.4 EEA08374.1 - 0.4 10.4 0.1 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 Phage holin family 6 YMF19 PF02326.10 EEA08375.1 - 0.037 14.5 0.7 0.037 14.5 0.5 2.0 1 1 1 2 2 2 0 Plant ATP synthase F0 OPT PF03169.10 EEA08375.1 - 0.042 12.2 1.9 0.048 12.0 1.3 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF997 PF06196.7 EEA08375.1 - 0.22 11.0 2.3 0.78 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) FixP_N PF14715.1 EEA08375.1 - 6.1 6.3 8.1 2.1 7.8 0.8 2.2 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Adaptin_N PF01602.15 EEA08376.1 - 1.3e-51 175.5 21.5 1.3e-51 175.5 14.9 2.0 2 0 0 2 2 2 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 EEA08376.1 - 0.00045 20.0 0.5 0.0014 18.5 0.4 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 EEA08376.1 - 0.0062 16.5 0.1 6.3 7.1 0.1 3.6 3 0 0 3 3 3 2 HEAT repeat Hormone_3 PF00159.13 EEA08377.1 - 0.0041 17.1 4.0 0.42 10.6 0.0 3.5 3 0 0 3 3 3 2 Pancreatic hormone peptide AGTRAP PF06396.6 EEA08377.1 - 7.6 6.2 12.9 7.1 6.3 6.8 2.4 2 1 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Pkinase PF00069.20 EEA08379.1 - 7.8e-37 126.8 0.1 5.1e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08379.1 - 2e-18 66.4 0.2 2.7e-08 33.1 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA08379.1 - 3.1e-06 26.3 0.0 0.005 15.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 EEA08379.1 - 0.00012 21.0 0.6 0.00019 20.3 0.4 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Abhydrolase_5 PF12695.2 EEA08380.1 - 1.5e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA08380.1 - 4.3e-05 23.4 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA08380.1 - 0.00012 21.3 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EEA08380.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Cpn60_TCP1 PF00118.19 EEA08381.1 - 9.2e-112 374.1 9.8 1.2e-111 373.7 6.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_5 PF12695.2 EEA08382.1 - 1.3e-19 70.4 0.0 1.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA08382.1 - 1.4e-07 31.6 0.0 1.6e-05 24.9 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA08382.1 - 9.5e-05 21.7 0.0 0.00046 19.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEA08382.1 - 0.0005 19.5 0.3 0.011 15.1 0.2 2.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EEA08382.1 - 0.00066 18.4 0.0 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 EEA08382.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EEA08382.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 EEA08382.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 EEA08382.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EEA08382.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family HEAT PF02985.17 EEA08383.1 - 1.3e-16 59.1 7.5 0.038 14.0 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EEA08383.1 - 3.5e-07 30.4 0.0 2.6 8.3 0.0 6.3 5 1 3 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 EEA08383.1 - 7e-05 23.1 0.1 32 5.1 0.0 5.7 4 1 1 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA08383.1 - 0.0074 16.6 3.2 0.53 10.6 0.3 4.5 4 1 2 6 6 6 2 Vacuolar 14 Fab1-binding region WD40 PF00400.27 EEA08384.1 - 3.6e-08 32.9 7.7 0.0016 18.2 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat CS PF04969.11 EEA08385.1 - 0.048 14.2 2.4 1.4 9.5 1.7 2.4 1 1 0 1 1 1 0 CS domain Tfb4 PF03850.9 EEA08386.1 - 1.2e-25 90.3 8.4 1.7e-25 89.8 5.9 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 FHA PF00498.21 EEA08386.1 - 0.35 11.0 2.7 3 8.0 0.0 3.1 3 1 0 3 3 3 0 FHA domain zf-AN1 PF01428.11 EEA08386.1 - 0.43 10.5 6.2 0.92 9.4 4.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger RNA_pol_Rpb2_7 PF04560.15 EEA08387.1 - 0.064 13.5 0.2 6.7 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 7 Pkinase PF00069.20 EEA08388.1 - 3.1e-34 118.3 0.0 5.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08388.1 - 5.5e-14 51.8 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA08388.1 - 0.00039 19.4 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EEA08388.1 - 0.0067 15.7 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Ribophorin_I PF04597.9 EEA08389.1 - 3.5e-86 289.3 18.1 4.1e-86 289.2 12.6 1.0 1 0 0 1 1 1 1 Ribophorin I Hormone_6 PF00236.13 EEA08389.1 - 0.085 12.6 0.2 0.86 9.4 0.1 2.3 2 0 0 2 2 2 0 Glycoprotein hormone Cpn60_TCP1 PF00118.19 EEA08390.1 - 9.4e-135 449.9 8.1 1.1e-134 449.7 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SGT1 PF07093.6 EEA08391.1 - 5.7e-38 130.6 2.2 5.7e-38 130.6 1.5 2.4 1 1 0 2 2 2 2 SGT1 protein V-SNARE PF05008.10 EEA08391.1 - 0.17 12.0 2.8 0.17 12.0 0.3 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DNA_pol_B PF00136.16 EEA08392.1 - 2.6e-48 164.9 0.2 4.2e-47 160.9 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.1 EEA08392.1 - 0.00018 21.4 8.5 0.00018 21.4 5.9 2.9 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta Mannosyl_trans2 PF04188.8 EEA08394.1 - 1.8e-35 122.7 53.2 4.5e-35 121.4 36.9 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) SF3a60_bindingd PF12108.3 EEA08394.1 - 0.012 15.1 0.9 0.028 13.9 0.6 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain zf-HC5HC2H_2 PF13832.1 EEA08397.1 - 1.4e-09 37.9 21.9 2.8e-08 33.7 7.3 3.7 3 1 0 3 3 3 2 PHD-zinc-finger like domain PHD_2 PF13831.1 EEA08397.1 - 6.4e-07 28.5 2.0 6.4e-07 28.5 1.4 4.0 4 1 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.1 EEA08397.1 - 1.2e-06 28.5 13.5 1.2e-06 28.5 9.3 3.8 2 2 1 3 3 3 1 PHD-like zinc-binding domain C1_1 PF00130.17 EEA08397.1 - 2.9e-05 23.6 14.1 0.00041 20.0 0.4 4.0 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EEA08397.1 - 4.3e-05 23.1 4.5 4.3e-05 23.1 3.2 4.2 5 1 0 5 5 5 2 PHD-finger Prok-RING_1 PF14446.1 EEA08397.1 - 7.3 6.4 22.4 0.3 10.8 0.6 3.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Met_10 PF02475.11 EEA08398.1 - 2.6e-44 151.2 0.1 5.1e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEA08398.1 - 9e-07 28.9 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA08398.1 - 7e-05 22.4 2.1 0.00013 21.6 0.1 2.4 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EEA08398.1 - 0.00013 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EEA08398.1 - 0.00014 22.4 0.0 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.12 EEA08398.1 - 0.0033 16.6 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PrmA PF06325.8 EEA08398.1 - 0.0046 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEA08398.1 - 0.016 15.6 0.0 0.053 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EEA08398.1 - 0.034 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TRM PF02005.11 EEA08398.1 - 0.037 12.9 0.2 0.093 11.6 0.1 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.6 EEA08398.1 - 0.038 12.6 1.8 0.32 9.6 0.1 2.2 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_12 PF08242.7 EEA08398.1 - 0.062 13.7 0.1 0.59 10.6 0.0 2.6 3 0 0 3 3 2 0 Methyltransferase domain Lectin_leg-like PF03388.8 EEA08399.1 - 1.6e-18 66.6 0.0 3.6e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 Legume-like lectin family COG5 PF10392.4 EEA08399.1 - 0.046 13.6 4.2 0.11 12.5 2.6 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF2225 PF09986.4 EEA08399.1 - 0.076 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) WWE PF02825.15 EEA08400.1 - 2.6e-13 49.2 9.5 1.6e-09 37.0 2.1 2.8 2 0 0 2 2 2 2 WWE domain zf-RING_2 PF13639.1 EEA08400.1 - 7.4e-07 28.9 11.3 1.7e-06 27.7 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 EEA08400.1 - 0.00046 19.6 7.1 0.0012 18.3 4.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EEA08400.1 - 0.01 15.8 12.7 0.027 14.4 8.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA08400.1 - 0.011 15.8 5.7 0.011 15.8 3.9 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EEA08400.1 - 0.044 13.6 4.9 0.13 12.0 3.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EEA08400.1 - 0.13 11.8 17.6 0.02 14.5 9.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA08400.1 - 5.4 6.8 11.5 11 5.8 8.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain CAMSAP_CKK PF08683.6 EEA08401.1 - 5.1e-24 84.3 1.8 5.5e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF1091 PF06477.8 EEA08402.1 - 0.035 14.5 3.0 0.11 12.9 2.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DUF4206 PF13901.1 EEA08405.1 - 2.8e-10 40.0 10.0 1.3e-09 37.8 1.3 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4206) Enkurin PF13864.1 EEA08405.1 - 1.2 9.4 5.9 1.4 9.1 0.8 2.8 3 0 0 3 3 3 0 Calmodulin-binding IFP_35_N PF07334.8 EEA08406.1 - 0.015 15.2 0.6 0.048 13.6 0.4 1.9 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Siah-Interact_N PF09032.6 EEA08406.1 - 0.091 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal TMF_DNA_bd PF12329.3 EEA08406.1 - 0.31 10.8 3.6 0.62 9.9 2.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 EEA08407.1 - 3.6e-61 206.5 0.2 3.2e-60 203.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08407.1 - 4.7e-34 117.6 0.0 7.5e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA08407.1 - 7.7e-07 28.3 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA08407.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EEA08408.1 - 6.5e-21 74.4 0.3 1.6e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.1 EEA08408.1 - 8.5e-10 38.6 0.6 3.9e-09 36.5 0.2 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.1 EEA08408.1 - 0.001 18.6 0.1 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 ABC_tran PF00005.22 EEA08409.1 - 2.5e-48 163.8 3.0 4.4e-24 85.3 0.0 3.3 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 EEA08409.1 - 1.5e-20 72.8 0.7 1.5e-20 72.8 0.5 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EEA08409.1 - 2.8e-19 70.1 32.1 9.4e-09 35.6 0.6 5.8 4 2 1 5 5 5 3 AAA domain SMC_N PF02463.14 EEA08409.1 - 5.5e-11 42.1 5.6 0.00099 18.3 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA08409.1 - 5.2e-08 32.3 1.7 0.00066 19.1 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEA08409.1 - 6.2e-07 30.2 4.3 0.011 16.5 0.1 4.0 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 EEA08409.1 - 1.1e-06 29.1 0.0 0.077 13.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EEA08409.1 - 3.6e-06 27.4 0.2 3.6e-06 27.4 0.1 4.4 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EEA08409.1 - 0.00019 20.6 0.1 0.67 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA08409.1 - 0.00038 20.6 6.6 0.24 11.5 0.4 4.3 4 3 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EEA08409.1 - 0.00047 19.6 0.1 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EEA08409.1 - 0.00087 18.9 0.9 0.72 9.4 0.2 2.6 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.18 EEA08409.1 - 0.00088 19.1 0.2 0.18 11.5 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_14 PF13173.1 EEA08409.1 - 0.0015 18.3 4.1 1.7 8.5 0.0 4.6 4 1 1 5 5 4 1 AAA domain AAA_15 PF13175.1 EEA08409.1 - 0.0021 17.1 0.3 0.0021 17.1 0.2 6.3 3 1 3 6 6 5 3 AAA ATPase domain AAA_33 PF13671.1 EEA08409.1 - 0.0023 17.8 0.1 0.36 10.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEA08409.1 - 0.0028 16.5 0.0 1.6 7.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain MobB PF03205.9 EEA08409.1 - 0.0028 17.3 0.3 0.57 9.8 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EEA08409.1 - 0.003 16.5 0.1 0.1 11.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EEA08409.1 - 0.0038 17.5 11.7 0.035 14.4 0.0 4.3 5 1 0 5 5 3 2 AAA domain AAA_10 PF12846.2 EEA08409.1 - 0.0047 16.3 0.0 1.5 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA-like domain DUF3584 PF12128.3 EEA08409.1 - 0.0052 14.2 0.2 0.0052 14.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) SbcCD_C PF13558.1 EEA08409.1 - 0.0062 16.4 0.0 2.8 7.9 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EEA08409.1 - 0.0077 16.2 0.3 7 6.5 0.3 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EEA08409.1 - 0.012 15.6 0.6 0.96 9.3 0.6 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEA08409.1 - 0.013 15.6 0.1 9 6.5 0.0 3.1 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.18 EEA08409.1 - 0.015 15.2 1.1 1.8 8.5 0.0 3.5 2 1 1 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EEA08409.1 - 0.022 14.4 0.6 2.2 7.9 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EEA08409.1 - 0.046 13.4 0.1 0.52 10.0 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain cobW PF02492.14 EEA08409.1 - 0.053 12.9 0.3 4.9 6.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EEA08409.1 - 0.069 12.9 9.5 5.8 6.6 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function DUF87 DEAD PF00270.24 EEA08409.1 - 0.082 12.4 0.0 10 5.5 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.24 EEA08409.1 - 0.11 12.6 0.4 13 6.0 0.0 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EEA08409.1 - 0.11 11.1 0.4 12 4.5 0.0 2.6 3 0 0 3 3 3 0 ArgK protein TT_ORF2a PF08197.6 EEA08410.1 - 0.35 10.6 0.1 0.82 9.4 0.0 1.5 1 0 0 1 1 1 0 pORF2a truncated protein AP2 PF00847.15 EEA08413.1 - 7e-37 125.3 11.7 7.7e-11 41.9 0.2 4.5 4 0 0 4 4 4 4 AP2 domain ABC2_membrane PF01061.19 EEA08416.1 - 7e-32 110.2 26.3 1.5e-31 109.2 18.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEA08416.1 - 8e-22 78.0 0.0 1.6e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EEA08416.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EEA08416.1 - 2.1e-05 24.6 17.6 0.00022 21.2 0.1 3.6 2 1 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EEA08416.1 - 2.2e-05 23.6 35.4 2.2e-05 23.6 24.5 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 EEA08416.1 - 6.2e-05 22.3 1.4 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA08416.1 - 0.00026 21.7 2.5 0.00031 21.5 0.2 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEA08416.1 - 0.00085 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EEA08416.1 - 0.0011 19.2 0.5 0.0038 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA08416.1 - 0.0015 17.7 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA08416.1 - 0.0019 17.6 0.1 0.33 10.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA08416.1 - 0.0031 16.9 0.2 0.0078 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArgK PF03308.11 EEA08416.1 - 0.0058 15.4 0.1 0.0099 14.6 0.1 1.3 1 0 0 1 1 1 1 ArgK protein AAA_15 PF13175.1 EEA08416.1 - 0.018 14.0 10.5 0.13 11.3 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 EEA08416.1 - 0.025 14.3 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 NTPase Dynamin_N PF00350.18 EEA08416.1 - 0.048 13.4 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Arch_ATPase PF01637.13 EEA08416.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EEA08416.1 - 0.073 12.4 0.1 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EEA08416.1 - 0.076 11.8 0.5 0.12 11.2 0.4 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EEA08416.1 - 0.23 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.6 EEA08421.1 - 0.00021 21.1 90.8 0.00038 20.2 37.6 3.5 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) PRCC PF10253.4 EEA08421.1 - 2.5 8.7 5.3 7.5 7.1 3.6 1.8 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Zn_ribbon_2 PF12674.2 EEA08422.1 - 0.01 16.1 0.7 0.066 13.5 0.5 2.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Hid1 PF12722.2 EEA08424.1 - 9.7e-05 20.2 19.7 0.0001 20.1 13.7 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EEA08424.1 - 0.0011 17.6 47.6 0.0015 17.1 33.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CENP-T PF15511.1 EEA08424.1 - 0.14 11.3 39.4 0.22 10.7 27.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 EEA08424.1 - 0.2 10.6 49.1 0.29 10.1 34.0 1.2 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.8 EEA08424.1 - 0.35 8.9 48.5 0.45 8.6 33.6 1.1 1 0 0 1 1 1 0 Utp14 protein PLRV_ORF5 PF01690.12 EEA08424.1 - 0.87 8.6 31.2 1.4 7.9 21.6 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Med15 PF09606.5 EEA08424.1 - 1.3 7.0 34.3 1.7 6.7 23.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mitofilin PF09731.4 EEA08424.1 - 6 5.3 43.9 8.7 4.8 30.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC_tran PF00005.22 EEA08426.1 - 3.7e-28 98.5 0.0 5.8e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EEA08426.1 - 2.5e-24 85.6 33.9 2.5e-24 85.6 23.5 1.5 2 0 0 2 2 1 1 ABC-2 type transporter AAA_21 PF13304.1 EEA08426.1 - 4e-09 36.8 19.0 7.3e-07 29.4 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEA08426.1 - 8.7e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EEA08426.1 - 1.8e-05 24.0 0.0 0.03 13.5 0.0 2.9 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EEA08426.1 - 7.2e-05 21.9 40.7 7.2e-05 21.9 28.2 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EEA08426.1 - 0.00033 19.8 0.1 0.00055 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEA08426.1 - 0.00054 19.7 0.0 0.00094 18.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EEA08426.1 - 0.0017 18.0 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_35 PF14516.1 EEA08426.1 - 0.0038 15.9 0.0 0.0064 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EEA08426.1 - 0.0049 17.6 0.0 0.0097 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEA08426.1 - 0.012 15.8 1.3 0.016 15.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA08426.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEA08426.1 - 0.015 14.7 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EEA08426.1 - 0.021 14.2 0.6 0.037 13.4 0.4 1.3 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 EEA08426.1 - 0.021 13.8 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EEA08426.1 - 0.024 14.3 0.2 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EEA08426.1 - 0.028 14.0 0.1 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EEA08426.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEA08426.1 - 0.035 13.5 0.1 0.065 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EEA08426.1 - 0.059 12.2 0.1 0.091 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EEA08426.1 - 0.072 13.2 0.2 0.2 11.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEA08426.1 - 0.073 13.2 0.2 0.2 11.8 0.0 1.9 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEA08426.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEA08426.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-gua_Ptrans PF00217.14 EEA08428.1 - 1.4e-95 319.2 0.0 1.7e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 EEA08428.1 - 5.7e-20 71.2 0.0 1.1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Patched PF02460.13 EEA08429.1 - 5.6e-102 342.0 0.3 1.1e-101 341.0 0.2 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EEA08429.1 - 2.5e-21 75.7 27.6 9.1e-21 73.9 7.2 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EEA08429.1 - 0.0028 15.1 6.2 0.0042 14.5 4.3 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Phtf-FEM1B_bdg PF12129.3 EEA08429.1 - 0.18 11.1 4.9 0.76 9.1 0.0 3.2 3 0 0 3 3 3 0 Male germ-cell putative homeodomain transcription factor Pkinase PF00069.20 EEA08430.1 - 2.8e-61 206.9 0.0 7.3e-61 205.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08430.1 - 6.3e-28 97.5 0.2 2.1e-23 82.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sybindin PF04099.7 EEA08431.1 - 2.4e-43 147.2 0.7 2.7e-43 147.0 0.5 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEA08431.1 - 5.1e-09 36.1 0.2 5.4e-09 36.0 0.1 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Pyr_redox_2 PF07992.9 EEA08432.1 - 3e-31 108.9 0.1 4.1e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEA08432.1 - 8e-21 74.1 0.0 4.4e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEA08432.1 - 5.3e-15 55.5 2.6 7.1e-10 39.1 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA08432.1 - 3.9e-09 36.8 0.0 4e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA08432.1 - 8.9e-08 31.3 1.9 6.3e-07 28.5 1.3 2.2 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EEA08432.1 - 1.1e-06 28.0 0.3 1.6e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA08432.1 - 1.1e-05 24.1 0.3 2.2e-05 23.1 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EEA08432.1 - 1.4e-05 24.2 1.9 0.0017 17.3 0.2 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EEA08432.1 - 1.8e-05 23.7 2.0 2e-05 23.6 0.6 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EEA08432.1 - 0.00012 21.2 0.4 0.00063 18.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEA08432.1 - 0.00058 19.8 4.3 0.00071 19.5 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEA08432.1 - 0.0032 16.5 1.9 0.76 8.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain RE_HpaII PF09561.5 EEA08432.1 - 0.013 14.6 1.0 0.96 8.5 0.0 2.3 2 0 0 2 2 2 0 HpaII restriction endonuclease PRCC PF10253.4 EEA08433.1 - 3.8e-06 27.7 6.7 4.7e-06 27.4 4.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Lys PF00062.15 EEA08433.1 - 0.12 12.3 5.6 0.15 12.0 3.4 1.5 1 1 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF870 PF05912.6 EEA08433.1 - 0.31 10.8 4.7 0.47 10.2 2.5 1.8 1 1 1 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) Maf PF02545.9 EEA08434.1 - 8.7e-33 113.0 0.9 1.1e-32 112.8 0.6 1.0 1 0 0 1 1 1 1 Maf-like protein GIY-YIG PF01541.19 EEA08435.1 - 1.2e-07 32.0 0.4 3.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 EEA08435.1 - 0.0014 18.3 4.8 0.0014 18.3 3.3 2.6 3 0 0 3 3 3 1 Ring finger domain T5orf172 PF10544.4 EEA08435.1 - 0.024 15.0 0.1 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 T5orf172 domain RINGv PF12906.2 EEA08435.1 - 0.93 9.5 5.9 1.2 9.1 3.0 2.2 2 0 0 2 2 2 0 RING-variant domain Peptidase_M16 PF00675.15 EEA08436.1 - 1.2e-25 90.0 0.0 6e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA08436.1 - 2.3e-11 43.7 0.4 1.7e-08 34.4 0.0 3.6 4 1 0 4 4 4 2 Peptidase M16 inactive domain Ribosomal_S6e PF01092.14 EEA08437.1 - 1.3e-55 186.4 0.2 2.4e-55 185.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e G-patch PF01585.18 EEA08438.1 - 1.6e-06 27.7 3.4 2.8e-06 26.9 2.3 1.4 1 0 0 1 1 1 1 G-patch domain Leu_zip PF15294.1 EEA08438.1 - 0.0036 16.4 0.8 0.0066 15.5 0.6 1.3 1 0 0 1 1 1 1 Leucine zipper Hydrolase PF00702.21 EEA08439.1 - 4e-19 69.8 0.4 8.2e-12 45.9 0.4 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA08439.1 - 1.2e-16 61.4 0.0 4.2e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA08439.1 - 3.1e-14 52.5 0.0 1.5e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EEA08439.1 - 0.013 14.9 0.0 0.048 13.1 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Annexin PF00191.15 EEA08440.1 - 0.0046 16.8 0.2 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 Annexin DUF2087 PF09860.4 EEA08441.1 - 0.042 13.6 1.7 0.062 13.0 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) FliJ PF02050.11 EEA08441.1 - 0.048 13.7 8.4 0.039 13.9 2.3 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4349 PF14257.1 EEA08441.1 - 0.079 12.1 0.8 0.14 11.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1664 PF07889.7 EEA08441.1 - 0.56 10.0 3.1 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EEA08441.1 - 0.8 9.4 16.6 0.16 11.7 4.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EEA08441.1 - 3.6 7.1 11.7 1.4 8.5 1.9 3.1 2 1 1 3 3 3 0 Septum formation initiator Solute_trans_a PF03619.11 EEA08442.1 - 1.9e-76 257.0 23.2 4.9e-76 255.6 16.1 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.24 EEA08443.1 - 3e-18 65.8 0.0 1.2e-17 63.9 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA08443.1 - 7.9e-09 35.2 0.0 3.1e-08 33.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAXNEB PF05625.6 EEA08444.1 - 0.0035 16.2 0.1 0.0044 15.8 0.1 1.1 1 0 0 1 1 1 1 PAXNEB protein DUF872 PF05915.7 EEA08445.1 - 5.4e-12 45.5 0.0 6.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) ABC2_membrane PF01061.19 EEA08445.1 - 0.0092 15.1 0.1 0.011 14.9 0.1 1.0 1 0 0 1 1 1 1 ABC-2 type transporter YrhK PF14145.1 EEA08445.1 - 0.0098 15.5 0.5 2.8 7.6 0.0 2.2 2 0 0 2 2 2 2 YrhK-like protein IMCp PF12314.3 EEA08447.1 - 4.7e-12 45.8 51.0 1.1e-05 25.4 12.6 3.4 1 1 2 3 3 3 3 Inner membrane complex protein HIF-1a_CTAD PF08778.5 EEA08447.1 - 0.00088 18.6 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain Tim17 PF02466.14 EEA08448.1 - 1.5e-29 102.5 2.9 2.4e-29 101.9 2.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family IncA PF04156.9 EEA08448.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 IncA protein Rho_N PF07498.7 EEA08449.1 - 9.6e-07 28.4 1.8 2.6e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain SAP PF02037.22 EEA08449.1 - 0.0014 18.1 0.0 0.0045 16.4 0.0 2.0 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EEA08449.1 - 0.015 14.8 0.0 0.049 13.1 0.0 1.9 1 0 0 1 1 1 0 HeH/LEM domain IncA PF04156.9 EEA08449.1 - 0.025 14.1 17.4 0.072 12.6 12.0 1.8 1 0 0 1 1 1 0 IncA protein DUF4463 PF14703.1 EEA08449.1 - 0.052 14.0 4.0 0.19 12.2 2.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) DUF501 PF04417.7 EEA08449.1 - 0.41 10.4 5.4 0.17 11.7 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF501) DUF148 PF02520.12 EEA08449.1 - 0.68 9.7 9.1 0.44 10.3 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 APG6 PF04111.7 EEA08449.1 - 5.2 6.0 19.0 3.9 6.4 11.9 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Pro_isomerase PF00160.16 EEA08450.1 - 4.8e-48 163.2 0.1 5.3e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EEA08450.1 - 0.033 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain CHCH PF06747.8 EEA08451.1 - 0.058 13.3 0.7 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 CHCH domain UQ_con PF00179.21 EEA08452.1 - 9.1e-07 28.3 0.3 9.1e-07 28.3 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme IncA PF04156.9 EEA08453.1 - 0.054 13.0 17.5 0.016 14.8 8.9 2.0 1 1 0 2 2 2 0 IncA protein KxDL PF10241.4 EEA08453.1 - 0.11 12.4 6.6 0.38 10.6 2.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein V-SNARE PF05008.10 EEA08453.1 - 0.11 12.6 12.6 0.042 13.9 6.7 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus BBP1_C PF15272.1 EEA08453.1 - 0.14 11.7 15.0 0.15 11.6 9.8 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ProRS-C_2 PF09181.5 EEA08453.1 - 0.19 11.6 1.9 0.26 11.2 0.1 2.2 2 1 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal UPF0242 PF06785.6 EEA08453.1 - 0.43 9.2 10.1 0.53 8.9 7.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Exonuc_VII_L PF02601.10 EEA08453.1 - 0.56 9.3 8.2 0.73 8.9 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.1 EEA08453.1 - 2.5 8.4 16.7 0.3 11.4 3.2 2.8 1 1 1 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.7 EEA08453.1 - 7.2 6.4 11.7 18 5.1 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_Eps PF04627.8 EEA08455.1 - 3.5e-06 26.4 0.0 4.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain MMR_HSR1 PF01926.18 EEA08456.1 - 3e-13 49.7 0.1 6.5e-12 45.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA08456.1 - 5.2e-05 22.5 0.4 0.0018 17.6 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEA08456.1 - 0.018 14.8 3.0 0.087 12.6 0.1 3.1 2 1 1 3 3 3 0 Dynamin family DUF258 PF03193.11 EEA08456.1 - 0.041 13.0 0.4 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ArgK PF03308.11 EEA08456.1 - 0.12 11.1 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Stork_head PF10264.4 EEA08457.1 - 0.049 13.8 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Rad51 PF08423.6 EEA08458.1 - 2.7e-15 55.9 0.1 2e-13 49.8 0.1 2.6 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 EEA08458.1 - 3.6e-08 32.8 3.1 2.9e-05 23.2 2.1 2.4 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 EEA08458.1 - 3.8e-08 32.9 0.0 1.5e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EEA08458.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PAXNEB PF05625.6 EEA08458.1 - 0.0096 14.7 1.0 0.023 13.5 0.0 1.9 2 0 0 2 2 2 1 PAXNEB protein SopA PF13981.1 EEA08459.1 - 0.0026 17.7 1.4 0.0061 16.5 1.0 1.6 1 0 0 1 1 1 1 SopA-like central domain DUF3336 PF11815.3 EEA08460.1 - 4.3e-35 120.3 1.7 8.4e-35 119.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEA08460.1 - 9.8e-23 81.1 0.0 1.8e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase SNF2_N PF00176.18 EEA08461.1 - 1.4e-30 106.1 0.0 1.3e-29 102.9 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA08461.1 - 5.7e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2862 PF11061.3 EEA08463.1 - 0.0027 17.3 0.6 0.0071 16.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2862) S1-P1_nuclease PF02265.11 EEA08463.1 - 0.016 14.8 0.7 0.016 14.8 0.5 2.0 1 1 1 2 2 2 0 S1/P1 Nuclease UDPGT PF00201.13 EEA08463.1 - 0.054 12.0 2.2 0.067 11.7 1.5 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF2745 PF10922.3 EEA08463.1 - 0.064 13.1 1.3 0.67 9.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2745) Pex16 PF08610.5 EEA08463.1 - 0.094 11.6 2.4 0.14 11.1 1.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SF-assemblin PF06705.6 EEA08464.1 - 7.5e-10 38.3 26.1 4.9e-09 35.6 13.3 2.2 1 1 1 2 2 2 2 SF-assemblin/beta giardin Phage_GPO PF05929.6 EEA08464.1 - 0.024 13.9 3.9 5.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MtrG PF04210.8 EEA08464.1 - 0.031 13.9 1.8 12 5.6 0.1 3.6 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G SATase_N PF06426.9 EEA08464.1 - 0.18 12.0 4.0 1.3 9.3 0.1 3.0 1 1 2 3 3 3 0 Serine acetyltransferase, N-terminal DUF1192 PF06698.6 EEA08464.1 - 1.1 9.0 6.7 0.39 10.5 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Phage_Mu_Gam PF07352.7 EEA08464.1 - 8.4 5.9 11.5 1.4 8.4 1.1 3.6 3 2 1 4 4 4 0 Bacteriophage Mu Gam like protein AAA_2 PF07724.9 EEA08465.1 - 5.1e-36 124.1 2.3 3.5e-28 98.6 0.8 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEA08465.1 - 1.5e-12 47.8 4.7 2.3e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA08465.1 - 2.3e-06 28.4 0.3 6.5e-05 23.7 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EEA08465.1 - 2.5e-06 27.2 0.1 6.4e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MCM PF00493.18 EEA08465.1 - 2e-05 23.5 0.4 0.00039 19.3 0.0 2.4 2 0 0 2 2 2 1 MCM2/3/5 family AAA_18 PF13238.1 EEA08465.1 - 0.00024 21.3 1.1 0.00082 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 EEA08465.1 - 0.00026 20.8 0.9 0.0026 17.6 0.0 2.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.1 EEA08465.1 - 0.0003 20.9 0.0 0.0082 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA08465.1 - 0.0019 18.2 0.1 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 EEA08465.1 - 0.0024 17.3 0.0 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SE PF00437.15 EEA08465.1 - 0.0028 16.5 0.1 0.0057 15.5 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UPF0079 PF02367.12 EEA08465.1 - 0.0053 16.3 0.4 4.2 7.0 0.0 3.2 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EEA08465.1 - 0.0063 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEA08465.1 - 0.0073 15.4 0.0 0.033 13.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 EEA08465.1 - 0.0093 15.4 0.0 0.15 11.4 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EEA08465.1 - 0.017 14.2 0.1 0.05 12.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DUF465 PF04325.8 EEA08465.1 - 0.27 10.9 4.9 0.37 10.5 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TraX PF05857.6 EEA08466.1 - 0.0013 18.4 0.6 0.0018 17.9 0.4 1.3 1 0 0 1 1 1 1 TraX protein DUF1600 PF07667.6 EEA08466.1 - 0.0056 16.7 5.1 0.0056 16.7 3.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1600) EF-hand_1 PF00036.27 EEA08467.1 - 8e-08 31.0 18.9 0.029 13.6 0.5 6.0 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 EEA08467.1 - 1.8e-05 24.2 13.4 0.3 11.0 0.1 5.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EEA08467.1 - 6.1e-05 23.0 1.9 6.1e-05 23.0 1.4 5.2 5 2 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 EEA08467.1 - 0.083 12.2 25.4 0.11 11.9 0.2 5.5 6 0 0 6 6 6 0 EF hand EF-hand_8 PF13833.1 EEA08467.1 - 0.18 11.4 19.6 0.73 9.4 0.8 5.9 6 0 0 6 6 6 0 EF-hand domain pair Myb_DNA-binding PF00249.26 EEA08468.1 - 9.7e-14 51.1 0.4 1.6e-13 50.4 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA08468.1 - 0.00044 20.2 0.1 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.17 EEA08469.1 - 1.9e-26 91.4 0.0 6.5e-19 67.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA08469.1 - 5.5e-23 80.7 0.1 2e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA08469.1 - 3.1e-12 46.1 0.7 3.1e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EEA08469.1 - 7.6e-06 25.6 0.3 0.061 13.0 0.0 2.6 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EEA08469.1 - 9.5e-05 22.0 0.1 0.32 10.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF3201 PF11447.3 EEA08469.1 - 0.1 12.0 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) V-ATPase_H_N PF03224.9 EEA08470.1 - 2.2e-52 178.1 1.5 4e-52 177.2 1.0 1.4 1 1 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EEA08470.1 - 5.8e-43 145.5 0.4 1.4e-42 144.3 0.3 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 EEA08470.1 - 0.0022 17.7 1.2 5.3 7.0 0.0 4.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEA08470.1 - 0.023 14.9 0.1 0.43 10.8 0.0 3.0 3 2 1 4 4 4 0 HEAT repeats EF1_GNE PF00736.14 EEA08471.1 - 5.8e-27 93.2 1.9 5.8e-27 93.2 1.3 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Poty_PP PF08440.5 EEA08471.1 - 0.00089 18.3 0.5 0.0012 17.9 0.3 1.1 1 0 0 1 1 1 1 Potyviridae polyprotein EF-1_beta_acid PF10587.4 EEA08471.1 - 0.026 14.6 2.2 0.026 14.6 1.5 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF466 PF04328.8 EEA08471.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF466) DS PF01916.12 EEA08473.1 - 6.1e-123 409.7 0.0 7.3e-123 409.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MIF4G PF02854.14 EEA08474.1 - 2.2e-28 99.1 9.3 3.7e-28 98.3 6.5 1.4 1 0 0 1 1 1 1 MIF4G domain Pkinase PF00069.20 EEA08477.1 - 3.8e-43 147.5 0.1 3.4e-39 134.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08477.1 - 1.8e-28 99.3 0.0 1.5e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA08477.1 - 3.1e-09 36.2 0.0 4.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA08477.1 - 0.0028 17.4 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA08477.1 - 0.037 13.0 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_25 PF13481.1 EEA08478.1 - 5.1e-07 29.2 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EEA08478.1 - 0.00033 19.6 0.0 0.00066 18.6 0.0 1.6 1 0 0 1 1 1 1 Rad51 ABC_tran PF00005.22 EEA08478.1 - 0.061 13.6 0.4 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Fe-S_biosyn PF01521.15 EEA08479.1 - 1.3e-07 31.4 1.4 4.9e-07 29.6 0.9 1.9 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ABC_tran PF00005.22 EEA08480.1 - 1.2e-26 93.6 1.9 9.8e-14 51.8 0.0 3.9 3 0 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 EEA08480.1 - 0.00067 19.1 2.6 0.38 10.3 0.1 2.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA08480.1 - 0.00096 19.0 1.3 0.075 12.9 0.0 3.7 4 0 0 4 4 4 1 50S ribosome-binding GTPase Miro PF08477.8 EEA08480.1 - 0.0024 18.3 0.8 0.52 10.8 0.0 3.8 3 0 0 3 3 3 1 Miro-like protein AAA_25 PF13481.1 EEA08480.1 - 0.012 14.9 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA08480.1 - 0.025 14.0 0.6 6.9 6.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 EEA08480.1 - 0.033 13.3 0.5 0.3 10.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 MobB PF03205.9 EEA08480.1 - 0.11 12.1 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B E1-E2_ATPase PF00122.15 EEA08480.1 - 9.9 5.1 9.2 32 3.4 0.1 2.7 2 0 0 2 2 2 0 E1-E2 ATPase zf-B_box PF00643.19 EEA08481.1 - 1.7e-09 37.3 15.5 2.2e-05 24.2 0.8 2.7 2 0 0 2 2 2 2 B-box zinc finger PARP PF00644.15 EEA08481.1 - 0.0016 17.9 1.9 0.022 14.1 0.7 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain FH2 PF02181.18 EEA08482.1 - 5.9e-14 51.7 16.9 8e-09 34.8 3.5 2.8 3 0 0 3 3 3 2 Formin Homology 2 Domain RE_Eco29kI PF09517.5 EEA08483.1 - 0.064 12.5 0.1 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Lysine_decarbox PF03641.9 EEA08483.1 - 0.14 11.9 0.1 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Possible lysine decarboxylase AA_permease_N PF08403.5 EEA08484.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal Imm2 PF14426.1 EEA08484.1 - 0.73 9.8 7.0 0.4 10.7 0.3 3.3 3 0 0 3 3 3 0 Immunity protein Imm2 NIF PF03031.13 EEA08485.1 - 3.3e-50 169.8 0.1 3.3e-50 169.8 0.1 2.7 2 1 1 3 3 3 1 NLI interacting factor-like phosphatase VirE PF05272.6 EEA08486.1 - 0.047 13.1 0.2 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Virulence-associated protein E EF-hand_1 PF00036.27 EEA08487.1 - 1e-11 43.1 1.7 8.8e-05 21.5 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EEA08487.1 - 1.9e-09 36.3 1.7 4.4e-05 22.6 0.4 2.7 2 1 1 3 3 3 2 EF hand EF-hand_7 PF13499.1 EEA08487.1 - 7.6e-09 35.5 0.9 1.7e-08 34.4 0.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EEA08487.1 - 2.3e-07 30.3 2.2 6.6e-05 22.4 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA08487.1 - 3.4e-06 26.4 1.2 0.0029 17.3 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EEA08487.1 - 2.9e-05 24.0 0.1 4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Hemocyanin_C PF03723.9 EEA08487.1 - 0.092 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, ig-like domain UFD1 PF03152.9 EEA08489.1 - 4.6e-26 91.0 1.3 6.9e-26 90.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 PRP21_like_P PF12230.3 EEA08489.1 - 0.075 12.5 0.1 0.075 12.5 0.1 4.7 6 0 0 6 6 6 0 Pre-mRNA splicing factor PRP21 like protein zf-FCS PF06467.9 EEA08489.1 - 3.4 7.3 14.3 0.77 9.4 0.1 4.0 4 1 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif LOH1CR12 PF10158.4 EEA08490.1 - 1.5 8.6 15.9 2.8 7.7 4.1 2.8 1 1 2 3 3 3 0 Tumour suppressor protein RabGAP-TBC PF00566.13 EEA08491.1 - 1.4e-41 142.3 2.5 1.4e-41 142.3 1.7 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Rep_fac_C PF08542.6 EEA08492.1 - 5.9e-19 67.8 0.0 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEA08492.1 - 8.3e-10 38.5 0.1 3e-09 36.7 0.0 2.0 2 1 1 3 3 3 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EEA08492.1 - 0.011 14.5 0.1 0.028 13.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEA08492.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PulS_OutS PF09691.5 EEA08492.1 - 0.019 14.9 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) RuvB_N PF05496.7 EEA08492.1 - 0.021 13.9 0.1 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EEA08492.1 - 0.04 12.6 0.2 0.11 11.2 0.1 1.9 1 1 1 2 2 2 0 TIP49 C-terminus AAA_16 PF13191.1 EEA08492.1 - 0.043 13.7 0.0 0.099 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EEA08493.1 - 8e-75 251.3 0.0 9.7e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA08493.1 - 9.6e-42 142.8 0.0 1.2e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA08493.1 - 5.2e-05 22.3 0.0 8.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEA08493.1 - 0.066 12.5 0.1 0.73 9.1 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.18 EEA08493.1 - 0.068 12.8 0.5 3 7.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEA08493.1 - 0.1 11.9 0.3 0.27 10.5 0.2 1.7 1 1 0 1 1 1 0 RIO1 family PGI PF00342.14 EEA08494.1 - 2.7e-162 540.5 0.0 3.4e-162 540.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase LSM14 PF12701.2 EEA08496.1 - 1.6e-32 111.2 0.1 5.1e-32 109.5 0.1 1.9 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EEA08496.1 - 1.1e-07 31.7 0.0 3.8e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.5 EEA08496.1 - 0.00074 20.0 18.6 0.0036 17.8 7.1 3.3 2 1 0 2 2 2 1 FDF domain LSM PF01423.17 EEA08496.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.7 1 0 0 1 1 1 1 LSM domain OmpH PF03938.9 EEA08496.1 - 0.035 14.0 1.4 0.063 13.2 0.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DnaJ PF00226.26 EEA08497.1 - 2.5e-26 91.1 3.3 6.3e-26 89.8 2.3 1.8 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EEA08497.1 - 1.2e-14 53.7 0.1 5.8e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA08497.1 - 0.00017 21.6 3.5 0.00025 21.1 0.5 2.8 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EEA08497.1 - 0.00059 19.5 0.4 0.0038 16.8 0.0 2.4 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_6 PF13848.1 EEA08497.1 - 0.00096 19.0 4.5 0.0017 18.2 0.4 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EEA08497.1 - 0.011 15.5 0.1 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 EEA08497.1 - 0.024 14.8 0.1 0.078 13.1 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain SET_assoc PF11767.3 EEA08497.1 - 0.031 13.5 0.2 0.42 9.9 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Redoxin PF08534.5 EEA08497.1 - 0.034 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 EEA08497.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein ArfGap PF01412.13 EEA08498.1 - 2.2e-33 114.5 0.5 2.2e-33 114.5 0.3 2.8 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf TPR_11 PF13414.1 EEA08499.1 - 2.3e-22 78.4 0.5 1.3e-14 53.5 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEA08499.1 - 6.5e-15 53.7 1.1 0.0001 21.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA08499.1 - 2.5e-14 52.1 3.3 1.6e-05 24.3 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA08499.1 - 2.8e-08 33.5 1.5 0.0095 15.8 0.5 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA08499.1 - 2e-07 31.0 2.2 0.028 15.0 0.1 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA08499.1 - 3.5e-07 30.7 0.3 0.014 16.0 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA08499.1 - 5.5e-07 29.8 5.6 0.0033 17.7 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA08499.1 - 8.8e-07 28.2 5.2 0.082 12.7 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA08499.1 - 1.2e-05 25.0 3.5 0.16 12.2 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA08499.1 - 3.5e-05 23.9 0.3 2.9 8.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA08499.1 - 9e-05 22.5 0.1 9e-05 22.5 0.1 3.9 4 1 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EEA08499.1 - 0.0025 17.2 0.1 0.0067 15.8 0.1 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 EEA08499.1 - 0.0037 16.9 0.0 38 4.4 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 EEA08499.1 - 0.072 13.1 0.9 10 6.3 0.0 4.6 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.1 EEA08499.1 - 0.075 12.9 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PGM_PMM_I PF02878.11 EEA08500.1 - 1.1e-27 96.1 0.0 1.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEA08500.1 - 1.8e-25 89.1 0.0 3.4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEA08500.1 - 3.5e-12 46.5 0.0 1.2e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA08500.1 - 1.8e-09 37.4 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.11 EEA08501.1 - 1.6e-25 89.2 0.1 2.4e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEA08501.1 - 3.8e-24 84.9 0.0 7.8e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEA08501.1 - 8.5e-12 45.3 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA08501.1 - 2.3e-06 27.5 0.0 6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3107 PF11305.3 EEA08502.1 - 0.23 11.3 2.5 0.26 11.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Lge1 PF11488.3 EEA08502.1 - 0.36 11.0 4.1 2.3 8.4 0.5 2.8 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Imm2 PF14426.1 EEA08504.1 - 0.54 10.2 4.9 4.7 7.2 0.2 3.4 2 2 1 3 3 3 0 Immunity protein Imm2 FliS PF02561.9 EEA08504.1 - 4.8 7.0 15.7 0.31 10.8 2.4 3.0 3 1 0 4 4 4 0 Flagellar protein FliS Dapper PF15268.1 EEA08505.1 - 2.1 7.0 2.9 3 6.5 2.0 1.1 1 0 0 1 1 1 0 Dapper Peptidase_C1 PF00112.18 EEA08506.1 - 8.5e-36 123.8 3.7 8.6e-20 71.5 0.2 2.6 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.6 EEA08506.1 - 8.3e-13 48.5 2.2 6.6e-10 39.1 0.6 2.6 1 1 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 EEA08506.1 - 0.00031 19.3 0.9 0.00059 18.4 0.6 1.3 1 0 0 1 1 1 1 Peptidase C1-like family HSP70 PF00012.15 EEA08507.1 - 3.5e-57 193.6 4.8 9.7e-57 192.2 0.1 3.3 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EEA08507.1 - 0.037 12.6 0.1 4.9 5.6 0.0 2.5 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.20 EEA08508.1 - 1.7e-08 33.9 0.0 5.5e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Lebercilin PF15619.1 EEA08509.1 - 0.0024 17.3 6.4 0.004 16.6 4.4 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease FH2 PF02181.18 EEA08509.1 - 0.0088 14.9 3.9 0.018 13.9 2.7 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain Pox_F16 PF04708.7 EEA08509.1 - 0.016 14.5 0.8 0.027 13.7 0.6 1.4 1 0 0 1 1 1 0 Poxvirus F16 protein DUF615 PF04751.9 EEA08509.1 - 0.081 12.5 4.2 0.18 11.4 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF615) IFT57 PF10498.4 EEA08509.1 - 0.084 11.6 9.6 0.11 11.1 6.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CutC PF03932.9 EEA08509.1 - 0.12 11.6 0.3 3.4 6.8 0.1 2.1 1 1 1 2 2 2 0 CutC family tRNA-synt_2b PF00587.20 EEA08509.1 - 0.15 11.5 1.4 0.31 10.6 1.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) APC_CDC26 PF10471.4 EEA08509.1 - 3.4 8.4 9.0 10 6.9 1.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PEP-utilisers_N PF05524.8 EEA08509.1 - 4.8 7.0 8.2 1.1e+02 2.5 5.7 2.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Atg14 PF10186.4 EEA08509.1 - 7.4 5.4 8.2 3.6 6.4 4.3 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SAC3_GANP PF03399.11 EEA08511.1 - 9.6e-26 90.6 1.6 1.3e-25 90.1 1.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEA08511.1 - 5.3e-22 78.1 0.0 1.1e-21 77.1 0.0 1.6 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 XPG_N PF00752.12 EEA08511.1 - 0.087 13.0 0.8 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 XPG N-terminal domain AlgF PF11182.3 EEA08512.1 - 0.39 10.3 4.4 0.07 12.8 0.6 1.5 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF DIRP PF06584.8 EEA08512.1 - 1.1 9.1 6.3 8.3 6.3 0.6 2.6 2 0 0 2 2 2 0 DIRP Gin PF10764.4 EEA08512.1 - 2.3 8.0 14.3 9.5 6.0 0.0 4.7 4 0 0 4 4 4 0 Inhibitor of sigma-G Gin CHASE3 PF05227.8 EEA08513.1 - 0.056 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 CHASE3 domain Dynamin_M PF01031.15 EEA08514.1 - 3.5e-87 291.9 1.5 3.5e-87 291.9 1.1 2.4 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 EEA08514.1 - 6.4e-48 162.7 0.1 6.4e-48 162.7 0.1 2.6 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 EEA08514.1 - 1.4e-26 92.2 3.2 4.5e-26 90.5 2.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEA08514.1 - 6e-05 22.9 0.3 6e-05 22.9 0.2 3.3 2 2 1 3 3 3 1 50S ribosome-binding GTPase Apolipo_F PF15148.1 EEA08514.1 - 0.0064 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein F Miro PF08477.8 EEA08514.1 - 0.012 16.1 0.2 0.048 14.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 EEA08515.1 - 2.4e-77 258.1 0.2 2.7e-77 257.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA08515.1 - 3.5e-14 52.4 0.0 4e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EEA08515.1 - 5.1e-13 48.6 0.0 6.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EEA08515.1 - 7.2e-11 41.4 1.2 1.3e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA08515.1 - 1.4e-10 40.7 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA08515.1 - 1.6e-09 38.2 0.0 2.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA08515.1 - 4.5e-06 26.6 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA08515.1 - 0.00028 20.3 0.1 0.0022 17.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA08515.1 - 0.0073 15.3 0.3 0.013 14.5 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEA08515.1 - 0.014 15.3 0.2 0.042 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain PDCD2_C PF04194.8 EEA08516.1 - 5.5e-33 113.8 5.3 5.6e-31 107.3 1.1 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain OAR PF03826.12 EEA08516.1 - 0.082 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 OAR domain DUF1297 PF06973.7 EEA08516.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Zn_Tnp_IS1595 PF12760.2 EEA08516.1 - 1.4 8.7 4.8 16 5.4 0.2 3.4 3 1 0 3 3 3 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 EEA08516.1 - 8.4 6.1 9.5 1.8 8.2 0.1 3.8 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) SDA1 PF05285.7 EEA08517.1 - 4.7e-33 114.8 41.3 1.1e-31 110.3 23.4 3.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EEA08517.1 - 2e-12 47.2 0.0 9.7e-12 44.9 0.0 2.3 1 0 0 1 1 1 1 NUC130/3NT domain DUF3464 PF11947.3 EEA08517.1 - 1.5 8.2 8.4 2.6 7.4 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Telomerase_RBD PF12009.3 EEA08519.1 - 6.6e-28 97.3 8.9 4.4e-27 94.6 6.1 2.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EEA08519.1 - 2.3e-10 40.1 0.0 4.6e-09 35.9 0.0 2.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.24 EEA08520.1 - 4.4e-24 85.0 2.5 5.3e-24 84.7 1.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA08520.1 - 4e-12 46.1 2.4 5e-12 45.8 1.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase XPC-binding PF09280.6 EEA08520.1 - 0.037 13.4 2.5 0.037 13.4 1.7 1.7 2 0 0 2 2 2 0 XPC-binding domain Glyco_hydro_65m PF03632.10 EEA08520.1 - 0.075 11.6 0.1 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Acyl_transf_3 PF01757.17 EEA08521.1 - 3.5e-15 55.6 47.1 5.4e-14 51.7 32.7 2.5 1 1 0 1 1 1 1 Acyltransferase family Peptidase_S7 PF00949.16 EEA08523.1 - 0.058 12.7 1.9 2.9 7.3 0.1 2.6 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease BLOC1_2 PF10046.4 EEA08524.1 - 9.7 6.4 10.4 0.53 10.4 0.6 3.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sedlin_N PF04628.8 EEA08525.1 - 1.4e-21 76.7 0.3 1.7e-21 76.4 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEA08525.1 - 0.0043 16.7 0.1 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family ORC5_C PF14630.1 EEA08525.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Myb_DNA-bind_3 PF12776.2 EEA08526.1 - 1.9 9.2 8.1 7.9 7.1 0.2 2.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GST_C PF00043.20 EEA08528.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA08528.1 - 0.077 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2535 PF10751.4 EEA08529.1 - 0.029 14.5 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) DUF98 PF01947.11 EEA08529.1 - 0.13 11.9 0.2 0.23 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF98) SNF2_N PF00176.18 EEA08531.1 - 2e-78 263.2 2.1 2e-78 263.2 1.5 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA08531.1 - 1.6e-15 56.7 0.0 4.2e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BOP1NT PF08145.7 EEA08533.1 - 4.7e-77 259.2 1.6 7e-77 258.6 1.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EEA08533.1 - 2.8e-05 23.8 2.2 12 5.9 0.1 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF3140 PF11338.3 EEA08533.1 - 0.014 15.4 0.1 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) BACK PF07707.10 EEA08534.1 - 0.0036 17.1 2.6 0.029 14.1 0.5 2.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3113 PF11310.3 EEA08534.1 - 2.7 7.7 8.1 0.33 10.6 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3113) Peptidase_S8 PF00082.17 EEA08535.1 - 3.3e-41 141.2 0.1 6.4e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 Subtilase family Bromodomain PF00439.20 EEA08537.1 - 0.0023 17.7 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Bromodomain WD40 PF00400.27 EEA08539.1 - 0.00017 21.3 5.4 0.00024 20.8 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat F-box-like PF12937.2 EEA08539.1 - 0.00072 19.2 2.3 0.00072 19.2 1.6 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA08539.1 - 0.98 9.1 12.1 0.52 10.0 3.0 3.4 3 0 0 3 3 3 0 F-box domain COX1 PF00115.15 EEA08541.1 - 2.2 6.8 0.0 3.7 6.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Dus PF01207.12 EEA08543.1 - 1.2e-37 129.4 0.0 8.1e-29 100.4 0.0 3.1 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) PrsW-protease PF13367.1 EEA08544.1 - 9.9e-15 54.2 8.0 7.6e-13 48.0 4.7 3.3 2 1 0 2 2 2 1 Protease prsW family Uteroglobin PF01099.12 EEA08544.1 - 0.052 13.3 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Uteroglobin family ERGIC_N PF13850.1 EEA08544.1 - 3.5 7.6 5.9 0.92 9.5 0.1 3.0 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nsp1_C PF05064.8 EEA08545.1 - 9e-14 51.1 11.7 3.9e-13 49.0 4.1 2.7 1 1 1 2 2 2 2 Nsp1-like C-terminal region DUF45 PF01863.12 EEA08545.1 - 0.026 14.3 1.1 0.047 13.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Filament PF00038.16 EEA08545.1 - 0.17 11.3 12.8 0.085 12.3 0.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein WXG100 PF06013.7 EEA08545.1 - 2 8.4 8.4 11 6.1 4.2 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 EEA08545.1 - 7.3 6.4 11.0 7 6.4 2.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit zf-HC5HC2H_2 PF13832.1 EEA08546.1 - 6.1e-18 64.8 17.0 4.2e-11 42.8 3.9 6.5 8 0 0 8 8 8 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEA08546.1 - 2e-13 50.2 19.8 8.9e-10 38.5 5.7 6.2 6 0 0 6 6 6 2 PHD-like zinc-binding domain PHD PF00628.24 EEA08546.1 - 6.2e-09 35.4 61.7 1.5e-06 27.7 7.6 6.1 5 1 1 6 6 6 3 PHD-finger DUF382 PF04037.8 EEA08547.1 - 3.7e-54 182.0 0.6 3.7e-54 182.0 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EEA08547.1 - 9.3e-21 72.9 6.9 9.3e-21 72.9 4.8 2.0 2 0 0 2 2 2 1 PSP SRP54_N PF02881.14 EEA08547.1 - 8.4 6.5 12.7 7.3 6.7 2.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain AP2 PF00847.15 EEA08549.1 - 2.2e-12 46.9 3.3 5.3e-12 45.7 2.3 1.7 1 0 0 1 1 1 1 AP2 domain Cytochrome_CBB3 PF13442.1 EEA08550.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF2024 PF09630.5 EEA08550.1 - 0.11 12.2 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-BED PF02892.10 EEA08550.1 - 0.15 11.8 3.2 0.53 10.0 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EEA08550.1 - 0.79 9.9 4.4 1.2 9.3 2.3 1.8 1 1 1 2 2 2 0 CHY zinc finger A2L_zn_ribbon PF08792.5 EEA08550.1 - 1.9 8.0 5.1 4 7.0 2.0 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain pKID PF02173.12 EEA08551.1 - 3.6e-06 26.1 18.4 1.7e+02 1.5 0.0 14.3 16 0 0 16 16 16 0 pKID domain TSP_1 PF00090.14 EEA08552.1 - 1.1e-19 70.2 40.4 1.4e-10 41.0 4.1 4.6 4 0 0 4 4 4 4 Thrombospondin type 1 domain Kringle PF00051.13 EEA08552.1 - 9e-10 38.5 2.7 2.4e-09 37.1 0.4 2.7 2 0 0 2 2 2 1 Kringle domain YhdB PF14148.1 EEA08552.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 YhdB-like protein OppC_N PF12911.2 EEA08552.1 - 0.68 9.3 4.6 0.22 10.9 0.4 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HMG_box PF00505.14 EEA08553.1 - 1.9e-15 56.8 4.9 1.9e-15 56.8 3.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA08553.1 - 1.5e-10 41.2 4.8 2.5e-10 40.5 3.3 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEA08553.1 - 0.00033 20.3 0.4 0.00055 19.6 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box 5 COX4 PF02936.9 EEA08553.1 - 0.014 15.1 0.3 0.022 14.5 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF2398 PF09661.5 EEA08553.1 - 0.034 12.8 0.2 0.044 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) Voldacs PF03517.8 EEA08556.1 - 1.5e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling bPH_3 PF14470.1 EEA08556.1 - 0.01 16.0 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial PH domain AAA PF00004.24 EEA08557.1 - 4e-53 179.1 0.1 3.3e-40 137.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA08557.1 - 6.1e-11 42.6 0.1 0.00035 20.6 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EEA08557.1 - 5.7e-10 39.4 4.1 0.00048 20.2 0.3 4.4 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEA08557.1 - 2.2e-08 33.9 0.1 0.00015 21.4 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEA08557.1 - 7.8e-08 32.2 1.6 0.013 15.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.9 EEA08557.1 - 4.4e-07 29.9 0.0 4e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EEA08557.1 - 2.5e-06 27.0 0.1 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.8 EEA08557.1 - 3.4e-06 26.0 0.2 0.03 13.0 0.0 2.7 3 0 0 3 3 3 2 TIP49 C-terminus Mg_chelatase PF01078.16 EEA08557.1 - 9.8e-06 24.8 0.1 0.00076 18.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEA08557.1 - 1.2e-05 25.3 0.0 0.043 13.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.1 EEA08557.1 - 1.3e-05 26.0 0.0 0.01 16.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA08557.1 - 1.7e-05 24.5 0.1 0.34 10.5 0.0 3.7 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.7 EEA08557.1 - 2.8e-05 23.2 0.1 0.0088 15.1 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA08557.1 - 6.2e-05 22.6 0.3 0.0019 17.9 0.1 2.7 2 1 1 3 3 2 1 Part of AAA domain ABC_tran PF00005.22 EEA08557.1 - 0.00021 21.6 0.2 0.069 13.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 EEA08557.1 - 0.00024 20.6 0.0 0.035 13.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEA08557.1 - 0.00033 19.8 0.1 1.2 8.1 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin Sigma54_activ_2 PF14532.1 EEA08557.1 - 0.00037 20.5 0.0 0.21 11.6 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EEA08557.1 - 0.0004 19.8 0.1 0.079 12.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EEA08557.1 - 0.00042 20.1 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEA08557.1 - 0.00049 19.0 0.4 0.53 9.0 0.0 2.9 4 0 0 4 4 4 2 NB-ARC domain AAA_18 PF13238.1 EEA08557.1 - 0.00051 20.3 0.0 0.045 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 EEA08557.1 - 0.00087 19.1 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 Torsin Arch_ATPase PF01637.13 EEA08557.1 - 0.0011 18.7 1.2 0.61 9.7 0.1 3.8 2 2 2 4 4 4 1 Archaeal ATPase AAA_24 PF13479.1 EEA08557.1 - 0.0016 18.0 0.4 0.056 13.0 0.2 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EEA08557.1 - 0.0021 17.1 0.2 0.031 13.3 0.0 2.7 3 0 0 3 3 2 1 KaiC IstB_IS21 PF01695.12 EEA08557.1 - 0.0025 17.2 0.0 0.16 11.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DAP3 PF10236.4 EEA08557.1 - 0.0029 16.5 0.1 0.095 11.6 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 EEA08557.1 - 0.0042 16.0 0.1 0.17 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 EEA08557.1 - 0.0045 16.5 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EEA08557.1 - 0.0071 15.2 0.0 0.088 11.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EEA08557.1 - 0.008 15.7 0.0 0.78 9.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EEA08557.1 - 0.012 14.6 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EEA08557.1 - 0.023 14.2 0.2 3 7.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.11 EEA08557.1 - 0.047 12.9 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 EEA08557.1 - 0.056 13.4 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain CDC48_2 PF02933.12 EEA08557.1 - 0.06 13.0 0.5 0.48 10.0 0.0 2.6 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 TrwB_AAD_bind PF10412.4 EEA08557.1 - 0.076 11.6 0.1 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.1 EEA08557.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_S9 PF00380.14 EEA08558.1 - 1.1e-33 116.0 0.1 1.3e-33 115.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2419 PF10343.4 EEA08558.1 - 0.068 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) Ribosomal_L13e PF01294.13 EEA08559.1 - 5.9e-55 185.4 2.2 7.5e-55 185.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e SPG48 PF14764.1 EEA08560.1 - 1.7e-08 33.4 1.5 0.00015 20.4 0.0 2.5 2 0 0 2 2 2 2 AP-5 complex subunit, vesicle trafficking SHS2_Rpb7-N PF03876.12 EEA08561.1 - 6.8e-13 48.5 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EEA08561.1 - 4.7e-08 33.2 0.0 7.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EEA08561.1 - 2.4e-06 27.5 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Metallophos PF00149.23 EEA08562.1 - 1.2e-35 122.7 2.4 1.9e-35 122.1 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EEA08562.1 - 7.8e-16 57.4 13.1 1.7e-11 43.6 1.7 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEA08562.1 - 3e-14 51.6 1.8 0.00014 21.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA08562.1 - 4e-14 51.5 3.9 0.00017 21.0 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 EEA08562.1 - 3.7e-13 49.2 2.4 5.6e-06 26.2 0.0 2.8 2 1 1 3 3 3 2 PPP5 TPR repeat region TPR_8 PF13181.1 EEA08562.1 - 2.6e-05 23.6 7.5 0.0051 16.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA08562.1 - 3.4e-05 23.6 4.5 0.0014 18.4 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA08562.1 - 0.0012 18.6 0.0 0.17 11.7 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA08562.1 - 0.0021 18.0 3.5 0.0058 16.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 EEA08563.1 - 1.4e-07 31.1 11.2 1.4e-07 31.1 7.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EEA08563.1 - 5.1e-07 29.6 7.5 1.5e-06 28.2 5.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EEA08563.1 - 4.3e-05 23.4 6.5 0.00016 21.5 4.5 2.1 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EEA08563.1 - 0.0012 18.4 12.9 0.0012 18.4 9.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA08563.1 - 0.0025 17.6 5.1 0.0069 16.2 3.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEA08563.1 - 0.0054 16.7 12.3 0.0054 16.7 8.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEA08563.1 - 0.042 13.9 10.1 0.13 12.3 7.0 2.0 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.1 EEA08563.1 - 0.24 11.1 12.7 0.41 10.4 7.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain C1_1 PF00130.17 EEA08563.1 - 0.65 9.7 10.1 2.1 8.1 7.0 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.1 EEA08563.1 - 0.8 9.4 7.5 12 5.7 5.2 3.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EEA08563.1 - 0.83 9.2 7.3 2.3 7.8 5.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KH_1 PF00013.24 EEA08564.1 - 3.2e-05 23.4 0.1 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEA08564.1 - 0.00091 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain GET2 PF08690.5 EEA08564.1 - 0.32 10.1 3.0 0.62 9.2 2.1 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 MbeD_MobD PF04899.7 EEA08565.1 - 0.65 9.9 15.2 2.2 8.2 1.2 4.3 3 1 1 4 4 4 0 MbeD/MobD like ER_lumen_recept PF00810.13 EEA08566.1 - 2.1e-36 125.6 7.5 2.1e-36 125.6 5.2 2.0 3 0 0 3 3 3 1 ER lumen protein retaining receptor gp37_C PF12604.3 EEA08566.1 - 0.044 13.5 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal WD40 PF00400.27 EEA08567.1 - 6.1e-29 98.8 16.7 1.5e-09 37.3 0.7 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Utp12 PF04003.7 EEA08567.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1513 PF07433.6 EEA08567.1 - 0.034 13.0 0.0 3.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Peptidase_M16_C PF05193.16 EEA08568.1 - 2.9e-23 82.5 1.0 3.7e-16 59.3 0.0 3.0 2 1 0 2 2 2 2 Peptidase M16 inactive domain DNA_pol_B PF00136.16 EEA08569.1 - 2.6e-106 356.2 0.7 5.3e-106 355.1 0.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEA08569.1 - 3e-23 82.2 3.2 2.6e-22 79.1 2.2 2.4 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EEA08569.1 - 1.6e-19 69.4 6.0 9.4e-19 66.9 4.2 2.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal V-SNARE_C PF12352.3 EEA08570.1 - 1.7e-06 27.9 0.8 1.9e-05 24.6 0.4 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3043 PF11241.3 EEA08570.1 - 0.006 16.1 0.1 0.056 13.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3043) Lip_prot_lig_C PF10437.4 EEA08570.1 - 0.022 14.4 0.3 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus TRM PF02005.11 EEA08570.1 - 0.034 13.0 0.2 0.6 8.9 0.0 2.0 1 1 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Mit_KHE1 PF10173.4 EEA08570.1 - 0.056 13.2 1.9 1.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related GKAP PF03359.8 EEA08570.1 - 0.08 12.5 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Shisa PF13908.1 EEA08570.1 - 0.32 11.1 1.7 0.47 10.6 1.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase_Tyr PF07714.12 EEA08571.1 - 1.3e-39 135.8 0.0 1.1e-37 129.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EEA08571.1 - 1.7e-38 132.2 0.0 1.5e-36 125.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SAM_2 PF07647.12 EEA08571.1 - 2.3e-05 24.1 0.2 8.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEA08571.1 - 0.031 14.4 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RNA_pol_Rpb4 PF03874.11 EEA08572.1 - 1.3e-17 63.8 0.7 1.6e-17 63.6 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF3839 PF12943.2 EEA08572.1 - 0.054 12.6 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Metallophos PF00149.23 EEA08573.1 - 5.4e-10 38.9 4.8 5.4e-10 38.9 3.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA08573.1 - 1.2e-05 25.1 0.2 3.1e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DBR1 PF05011.8 EEA08573.1 - 0.0067 16.3 0.7 0.011 15.6 0.5 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Rnk_N PF14760.1 EEA08574.1 - 0.11 12.6 0.2 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Rnk N-terminus Aa_trans PF01490.13 EEA08576.1 - 1.2e-45 155.7 48.9 2e-45 154.9 33.9 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEA08576.1 - 7.4e-07 28.3 17.2 7.4e-07 28.3 11.9 2.7 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DUF3733 PF12534.3 EEA08576.1 - 0.069 12.4 6.0 2.4 7.5 0.3 2.8 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Mucin PF01456.12 EEA08577.1 - 0.49 10.1 46.3 0.074 12.8 26.4 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Fib_alpha PF08702.5 EEA08578.1 - 0.063 13.3 11.3 0.045 13.8 6.4 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DegS PF05384.6 EEA08578.1 - 0.17 11.0 14.0 0.11 11.7 7.6 1.8 1 1 1 2 2 2 0 Sensor protein DegS DUF1840 PF08895.6 EEA08578.1 - 0.26 11.3 3.7 0.27 11.2 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) DUF262 PF03235.9 EEA08578.1 - 0.36 10.7 6.9 0.44 10.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 eIF3_subunit PF08597.5 EEA08578.1 - 0.41 10.1 14.4 0.046 13.2 6.9 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Ndc1_Nup PF09531.5 EEA08578.1 - 0.86 7.9 3.6 1 7.7 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ax_dynein_light PF10211.4 EEA08578.1 - 1.5 8.5 17.9 2.2 8.0 1.4 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain CDC37_N PF03234.9 EEA08578.1 - 1.6 9.0 14.8 12 6.2 10.3 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Allexi_40kDa PF05549.6 EEA08578.1 - 3.1 7.0 5.6 1.3 8.2 2.2 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Vfa1 PF08432.5 EEA08578.1 - 3.8 7.4 13.8 5.7 6.9 9.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mod_r PF07200.8 EEA08578.1 - 5.5 6.8 18.2 2.1 8.2 1.2 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.1 EEA08578.1 - 6.6 7.2 6.1 6.2 7.3 1.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SRP40_C PF05022.7 EEA08579.1 - 8.6e-24 83.8 3.6 8.6e-24 83.8 2.5 2.9 3 0 0 3 3 3 1 SRP40, C-terminal domain zf-CHY PF05495.7 EEA08579.1 - 0.15 12.2 2.5 0.2 11.8 0.9 1.9 1 1 1 2 2 2 0 CHY zinc finger Ribosomal_S17 PF00366.15 EEA08580.1 - 4.4e-28 97.1 2.2 4.6e-28 97.0 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 IL17 PF06083.6 EEA08580.1 - 0.19 11.8 1.9 0.18 11.9 0.4 1.6 2 0 0 2 2 2 0 Interleukin-17 IMS PF00817.15 EEA08581.1 - 5.2e-36 123.6 0.0 9.1e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEA08581.1 - 6e-09 35.8 0.1 2.3e-08 34.0 0.1 2.1 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF1805 PF08827.6 EEA08581.1 - 0.0091 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) RNase_PH PF01138.16 EEA08582.1 - 4.8e-26 91.6 0.5 9.8e-26 90.6 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PPI_Ypi1 PF07491.6 EEA08583.1 - 4.1e-21 74.3 9.4 9.1e-21 73.2 6.5 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF3124 PF11322.3 EEA08583.1 - 0.11 12.4 0.4 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) PC_rep PF01851.17 EEA08584.1 - 2.6e-39 131.2 17.1 6e-08 32.4 0.1 10.6 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEA08584.1 - 5.3e-17 61.8 0.0 1.3e-08 34.9 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EEA08584.1 - 8.9e-08 31.5 1.9 0.0014 18.5 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EEA08584.1 - 1.3e-05 25.4 0.1 0.028 14.9 0.1 4.1 2 1 2 4 4 4 3 HEAT-like repeat DUF1546 PF07571.8 EEA08584.1 - 0.026 14.6 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 EEA08584.1 - 0.13 12.8 2.4 19 6.0 0.0 4.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EEA08584.1 - 0.15 12.0 1.2 6.4 6.7 0.0 3.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Apc3 PF12895.2 EEA08584.1 - 0.59 10.3 11.3 0.34 11.0 0.5 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EEA08584.1 - 2.3 8.2 7.9 0.53 10.1 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA08584.1 - 3.5 7.7 9.4 0.38 10.8 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BLOC1_2 PF10046.4 EEA08585.1 - 0.029 14.5 5.8 0.83 9.8 0.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EEA08585.1 - 0.3 10.6 7.3 1.5 8.3 0.3 2.7 1 1 1 3 3 3 0 Septum formation initiator IncA PF04156.9 EEA08585.1 - 0.51 9.9 12.9 0.21 11.1 1.4 2.2 1 1 1 2 2 2 0 IncA protein Uds1 PF15456.1 EEA08585.1 - 0.76 9.7 8.6 2.8 7.9 6.0 1.9 1 1 0 1 1 1 0 Up-regulated During Septation DUF904 PF06005.7 EEA08585.1 - 0.79 10.0 12.3 7.8 6.8 0.7 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EEA08585.1 - 1.7 8.5 6.8 1.1 9.1 0.4 2.8 2 1 0 2 2 2 0 Basic region leucine zipper ERM PF00769.14 EEA08585.1 - 1.9 7.9 9.8 2.6 7.5 3.2 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3149 PF11346.3 EEA08586.1 - 1.1 8.8 7.1 1.9 8.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Vps51 PF08700.6 EEA08587.1 - 5.8e-11 42.0 0.8 5.8e-11 42.0 0.5 3.8 4 0 0 4 4 4 1 Vps51/Vps67 LIP PF03583.9 EEA08587.1 - 0.26 10.4 3.0 0.23 10.6 0.1 2.3 3 0 0 3 3 3 0 Secretory lipase Acetyltransf_1 PF00583.19 EEA08589.1 - 2.3e-13 49.9 0.0 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA08589.1 - 1.1e-10 41.6 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA08589.1 - 2.9e-08 33.7 0.0 4.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA08589.1 - 5e-06 26.4 0.0 6.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA08589.1 - 7.7e-06 25.9 0.1 9.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA08589.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEA08589.1 - 0.00062 19.4 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EEA08589.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA08589.1 - 0.0037 17.1 0.0 0.0067 16.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EEA08589.1 - 0.026 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1415 PF07209.7 EEA08589.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) DUF946 PF06101.6 EEA08589.1 - 0.11 10.4 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) PI3Ka PF00613.15 EEA08589.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DEC-1_N PF04625.8 EEA08591.1 - 0.018 13.7 7.7 0.023 13.4 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M16 PF00675.15 EEA08592.1 - 1.2e-35 122.5 0.0 2.3e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA08592.1 - 3e-16 59.6 0.2 6.2e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain P3A PF08727.6 EEA08592.1 - 0.12 11.7 0.1 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like eIF2_C PF09173.6 EEA08594.1 - 0.031 14.3 0.9 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 Initiation factor eIF2 gamma, C terminal VPR PF00522.13 EEA08594.1 - 0.13 12.1 0.1 0.13 12.1 0.0 3.3 4 0 0 4 4 4 0 VPR/VPX protein Peptidase_M16 PF00675.15 EEA08596.1 - 7.1e-15 55.0 0.6 1.5e-14 54.0 0.4 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA08596.1 - 8.2e-12 45.1 0.6 5.7e-11 42.4 0.0 2.7 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16_C PF05193.16 EEA08597.1 - 2.5e-09 37.0 1.4 8.5e-09 35.3 0.1 2.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA08597.1 - 7.3e-09 35.5 0.1 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Pkinase PF00069.20 EEA08599.1 - 1.6e-09 37.3 10.1 3.3e-05 23.1 0.0 4.0 4 1 0 4 4 4 2 Protein kinase domain Dpoe2NT PF12213.3 EEA08602.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 1 1 2 2 2 0 DNA polymerases epsilon N terminal SART-1 PF03343.8 EEA08604.1 - 9.7e-23 80.3 29.4 3.2e-20 72.0 0.3 2.4 1 1 1 2 2 2 2 SART-1 family DUF421 PF04239.7 EEA08604.1 - 0.026 14.0 2.6 0.12 11.9 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF421) FtsJ PF01728.14 EEA08605.1 - 4.9e-56 189.5 0.1 1.1e-55 188.3 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 EEA08605.1 - 9.4e-53 178.8 40.7 9.4e-53 178.8 28.2 3.2 2 1 0 2 2 2 1 Spb1 C-terminal domain DUF3381 PF11861.3 EEA08605.1 - 7.7e-24 83.9 21.9 7.7e-24 83.9 15.2 7.2 4 3 2 6 6 6 1 Domain of unknown function (DUF3381) DUF2962 PF11176.3 EEA08606.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) SURNod19 PF07712.7 EEA08606.1 - 0.041 12.3 0.1 0.05 12.0 0.1 1.1 1 0 0 1 1 1 0 Stress up-regulated Nod 19 Endonuc-MspI PF09208.5 EEA08606.1 - 0.062 12.3 0.1 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease MspI Bclx_interact PF08945.5 EEA08608.1 - 0.0012 18.3 15.1 1.2 8.7 1.6 5.7 5 0 0 5 5 5 3 Bcl-x interacting, BH3 domain HEAT_2 PF13646.1 EEA08608.1 - 0.029 14.6 1.8 1.4 9.2 0.1 3.3 2 1 0 2 2 2 0 HEAT repeats Dicty_REP PF05086.7 EEA08608.1 - 1.5 6.4 14.1 2.1 6.0 9.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 EEA08608.1 - 2.3 5.7 20.2 3.7 5.1 14.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Shisa PF13908.1 EEA08608.1 - 3.9 7.6 9.5 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Med15 PF09606.5 EEA08608.1 - 6.9 4.7 32.3 8.5 4.4 22.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2016 PF09436.5 EEA08609.1 - 6e-08 32.1 0.1 6.4 6.4 0.0 4.9 4 0 0 4 4 4 4 Domain of unknown function (DUF2016) DUF2775 PF10950.3 EEA08609.1 - 1.5e-06 28.3 0.0 17 5.6 0.0 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF2775) DUF493 PF04359.9 EEA08609.1 - 0.038 14.3 4.2 44 4.5 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Pik1 PF11522.3 EEA08609.1 - 0.21 11.3 4.6 60 3.4 0.1 3.8 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 P63C PF10546.4 EEA08609.1 - 6.3 6.8 9.6 1.4e+02 2.4 0.1 4.4 4 0 0 4 4 4 0 P63C domain Seryl_tRNA_N PF02403.17 EEA08611.1 - 0.00038 20.4 3.5 0.061 13.3 0.6 2.1 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FliJ PF02050.11 EEA08611.1 - 0.00055 19.9 0.7 0.00076 19.5 0.5 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DUF4446 PF14584.1 EEA08611.1 - 0.0019 18.0 0.3 0.23 11.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) FlxA PF14282.1 EEA08611.1 - 0.002 18.0 1.9 0.15 12.0 0.2 2.1 2 0 0 2 2 2 1 FlxA-like protein DUF342 PF03961.8 EEA08611.1 - 0.0022 16.4 1.1 0.0029 16.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 EEA08611.1 - 0.0024 16.3 0.4 0.0026 16.2 0.3 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.4 EEA08611.1 - 0.0028 17.7 1.3 0.13 12.3 0.4 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 EEA08611.1 - 0.0029 17.3 8.4 0.084 12.6 1.5 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EEA08611.1 - 0.0032 17.1 9.9 0.1 12.4 0.5 2.5 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat AAA_13 PF13166.1 EEA08611.1 - 0.0036 15.8 0.2 0.0041 15.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain Syntaxin-6_N PF09177.6 EEA08611.1 - 0.0037 17.6 0.3 0.35 11.2 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal TSC22 PF01166.13 EEA08611.1 - 0.0051 16.7 4.3 0.83 9.6 0.1 2.4 2 1 0 2 2 2 2 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 EEA08611.1 - 0.0055 16.4 3.7 0.029 14.1 0.6 2.0 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 EEA08611.1 - 0.0073 15.6 0.7 0.062 12.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) DUF4349 PF14257.1 EEA08611.1 - 0.0078 15.4 0.6 0.0078 15.4 0.4 1.4 2 0 0 2 2 1 1 Domain of unknown function (DUF4349) Vps51 PF08700.6 EEA08611.1 - 0.0099 15.6 0.9 0.079 12.8 0.1 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Phage_GP20 PF06810.6 EEA08611.1 - 0.011 15.2 2.4 0.15 11.4 0.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4140 PF13600.1 EEA08611.1 - 0.011 16.1 1.4 0.25 11.8 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.11 EEA08611.1 - 0.015 15.0 8.9 0.12 12.1 0.9 2.2 2 0 0 2 2 2 0 Hr1 repeat WXG100 PF06013.7 EEA08611.1 - 0.015 15.2 0.1 0.11 12.4 0.0 1.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DivIC PF04977.10 EEA08611.1 - 0.016 14.7 4.7 0.14 11.6 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator MutS_IV PF05190.13 EEA08611.1 - 0.018 15.2 1.3 1.2 9.3 0.3 2.3 2 0 0 2 2 2 0 MutS family domain IV Prefoldin_2 PF01920.15 EEA08611.1 - 0.022 14.5 8.5 0.073 12.8 1.8 2.1 2 0 0 2 2 2 0 Prefoldin subunit CCDC155 PF14662.1 EEA08611.1 - 0.023 14.3 2.8 0.036 13.6 2.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Erp_C PF06780.6 EEA08611.1 - 0.026 14.3 5.3 0.057 13.2 3.7 1.4 1 1 0 1 1 1 0 Erp protein C-terminus Nup54 PF13874.1 EEA08611.1 - 0.027 14.1 2.2 0.04 13.5 0.3 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 YgaB PF14182.1 EEA08611.1 - 0.028 14.6 0.4 0.028 14.6 0.3 2.0 2 0 0 2 2 2 0 YgaB-like protein AKNA PF12443.3 EEA08611.1 - 0.032 14.2 2.0 0.3 11.1 0.3 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor CHASE3 PF05227.8 EEA08611.1 - 0.041 13.5 0.3 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 CHASE3 domain DUF2730 PF10805.3 EEA08611.1 - 0.044 13.5 0.7 4.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 EEA08611.1 - 0.048 13.2 6.5 0.13 11.8 4.5 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 EEA08611.1 - 0.048 13.1 4.5 0.091 12.2 3.1 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like HALZ PF02183.13 EEA08611.1 - 0.054 13.2 1.8 0.054 13.2 1.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4201 PF13870.1 EEA08611.1 - 0.06 12.7 5.0 0.25 10.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SlyX PF04102.7 EEA08611.1 - 0.061 13.6 2.7 0.69 10.3 0.1 2.1 2 0 0 2 2 2 0 SlyX APG6 PF04111.7 EEA08611.1 - 0.064 12.2 2.1 0.086 11.8 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EEA08611.1 - 0.068 13.0 2.6 0.4 10.6 0.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaphilin PF15290.1 EEA08611.1 - 0.068 12.6 0.4 0.068 12.6 0.3 1.7 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp IncA PF04156.9 EEA08611.1 - 0.081 12.5 8.9 0.2 11.2 6.2 1.6 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EEA08611.1 - 0.082 13.1 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.6 EEA08611.1 - 0.096 13.0 2.5 4.8 7.6 0.2 2.2 2 0 0 2 2 2 0 MerR, DNA binding Prefoldin PF02996.12 EEA08611.1 - 0.099 12.2 7.5 0.23 11.0 1.7 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF2802 PF10975.3 EEA08611.1 - 0.1 12.4 1.0 1.9 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) EzrA PF06160.7 EEA08611.1 - 0.1 10.7 2.1 0.18 9.9 1.5 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Cep57_MT_bd PF06657.8 EEA08611.1 - 0.11 12.4 3.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.7 EEA08611.1 - 0.12 12.1 0.3 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NBP1 PF08537.5 EEA08611.1 - 0.14 11.2 3.6 4.5 6.3 0.6 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Sec2p PF06428.6 EEA08611.1 - 0.14 11.9 0.4 0.14 11.9 0.3 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EEA08611.1 - 0.15 11.9 4.2 0.62 9.8 0.8 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EEA08611.1 - 0.15 10.6 5.3 0.23 10.0 3.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Ax_dynein_light PF10211.4 EEA08611.1 - 0.18 11.6 4.6 0.26 11.1 3.0 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain DASH_Dam1 PF08653.5 EEA08611.1 - 0.19 11.5 0.5 15 5.4 0.0 2.8 3 0 0 3 3 2 0 DASH complex subunit Dam1 DivIVA PF05103.8 EEA08611.1 - 0.19 11.7 6.1 0.97 9.4 0.3 2.4 3 0 0 3 3 2 0 DivIVA protein HAP1_N PF04849.8 EEA08611.1 - 0.21 10.5 5.2 0.3 9.9 1.1 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF1319 PF07028.6 EEA08611.1 - 0.22 11.7 3.2 0.29 11.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin PF00804.20 EEA08611.1 - 0.23 11.6 2.7 0.48 10.6 1.9 1.5 1 1 0 1 1 1 0 Syntaxin DUF3573 PF12097.3 EEA08611.1 - 0.23 10.0 1.3 1.2 7.6 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) HTH_36 PF13730.1 EEA08611.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain MscS_porin PF12795.2 EEA08611.1 - 0.24 10.6 3.7 0.57 9.4 2.6 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3847 PF12958.2 EEA08611.1 - 0.24 11.1 7.4 0.18 11.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) ASD2 PF08687.6 EEA08611.1 - 0.28 10.4 3.6 1.2 8.4 0.2 2.0 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Rop-like PF05082.8 EEA08611.1 - 0.29 10.6 0.1 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Rop-like THOC7 PF05615.8 EEA08611.1 - 0.43 10.8 5.1 0.73 10.1 0.5 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Spc24 PF08286.6 EEA08611.1 - 0.43 10.2 6.9 0.6 9.8 1.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EEA08611.1 - 0.43 10.9 5.2 3.1 8.1 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Med9 PF07544.8 EEA08611.1 - 0.48 10.1 7.2 0.9 9.3 0.4 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 EEA08611.1 - 0.61 10.0 12.1 8.3 6.3 8.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2051 PF09738.4 EEA08611.1 - 0.71 9.1 6.3 2 7.6 4.3 1.6 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF4315 PF14193.1 EEA08611.1 - 0.79 9.6 11.3 2.2 8.2 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) BMFP PF04380.8 EEA08611.1 - 0.87 9.7 5.4 2.7 8.2 0.9 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity GrpE PF01025.14 EEA08611.1 - 0.98 8.9 5.5 8.4 5.9 3.8 2.0 1 1 0 1 1 1 0 GrpE Atg14 PF10186.4 EEA08611.1 - 1.1 8.0 8.1 0.36 9.7 2.6 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EEA08611.1 - 1.2 9.1 8.5 1.7 8.6 1.9 2.1 2 0 0 2 2 2 0 bZIP transcription factor DUF3373 PF11853.3 EEA08611.1 - 1.4 7.3 3.7 7.6 4.9 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Mnd1 PF03962.10 EEA08611.1 - 1.5 8.4 7.9 1.5 8.4 1.8 2.0 1 1 1 2 2 2 0 Mnd1 family DUF1090 PF06476.7 EEA08611.1 - 1.6 8.4 6.9 8.4 6.0 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) DUF3782 PF12644.2 EEA08611.1 - 1.6 8.5 5.8 11 5.8 4.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Phasin PF05597.6 EEA08611.1 - 1.7 8.3 4.5 3 7.5 0.6 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3166 PF11365.3 EEA08611.1 - 1.8 9.0 7.1 2.2 8.7 0.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3166) PCRF PF03462.13 EEA08611.1 - 1.8 8.3 5.1 16 5.2 0.8 2.1 1 1 1 2 2 2 0 PCRF domain TraC PF07820.7 EEA08611.1 - 2.2 8.5 6.8 1.3 9.2 1.0 2.2 2 0 0 2 2 2 0 TraC-like protein DUF2408 PF10303.4 EEA08611.1 - 3.4 7.7 6.5 4.6 7.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.2 EEA08611.1 - 3.9 7.3 8.7 20 5.0 6.0 1.8 1 1 0 1 1 1 0 Tropomyosin like GAS PF13851.1 EEA08611.1 - 4.5 6.3 11.1 63 2.6 7.6 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding RDM PF11002.3 EEA08611.1 - 5.4 6.7 6.0 1.9 8.2 0.7 2.4 2 0 0 2 2 2 0 RFPL defining motif (RDM) AAA_23 PF13476.1 EEA08611.1 - 8.4 6.6 10.8 16 5.7 7.5 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_M16 PF00675.15 EEA08612.1 - 4.1e-35 120.7 0.0 1.1e-34 119.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA08612.1 - 1.7e-19 70.1 3.4 1.7e-15 57.1 0.1 3.3 3 1 0 3 3 3 2 Peptidase M16 inactive domain Sugar_tr PF00083.19 EEA08613.1 - 1.3e-10 40.5 3.1 1.5e-10 40.2 2.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA08613.1 - 0.0018 17.0 6.2 0.002 16.8 4.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.7 EEA08613.1 - 0.021 14.1 6.2 0.025 13.9 4.3 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF389 PF04087.9 EEA08613.1 - 0.24 11.3 5.1 0.39 10.6 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF389) SNARE_assoc PF09335.6 EEA08613.1 - 1.8 8.7 7.4 13 5.9 5.1 1.9 1 1 0 1 1 1 0 SNARE associated Golgi protein ROK PF00480.15 EEA08614.1 - 6.2e-09 35.9 0.0 9.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 ROK family MarR PF01047.17 EEA08614.1 - 7.4e-06 25.5 0.1 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 EEA08614.1 - 1.8e-05 24.2 0.1 4.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 EEA08614.1 - 0.014 14.7 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EEA08614.1 - 0.049 13.4 0.1 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.18 EEA08614.1 - 0.1 12.1 0.1 0.37 10.3 0.1 1.9 1 1 0 1 1 1 0 MerR family regulatory protein HTH_CodY PF08222.6 EEA08614.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_15 PF12324.3 EEA08614.1 - 0.15 11.6 0.1 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Peptidase_M75 PF09375.5 EEA08616.1 - 0.0076 15.5 1.7 0.0096 15.2 1.2 1.1 1 0 0 1 1 1 1 Imelysin NPV_P10 PF05531.7 EEA08616.1 - 0.027 14.6 0.5 0.84 9.9 0.0 2.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ApoLp-III PF07464.6 EEA08616.1 - 0.028 14.4 0.3 0.9 9.5 0.0 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cytochrom_B562 PF07361.6 EEA08616.1 - 0.056 13.8 0.9 0.29 11.5 0.2 2.3 1 1 1 2 2 2 0 Cytochrome b562 Baculo_PEP_C PF04513.7 EEA08616.1 - 2.3 8.0 10.3 5.4 6.8 2.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpA_pilin PF09589.5 EEA08616.1 - 3.4 8.1 6.7 6 7.3 4.7 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein DUF3359 PF11839.3 EEA08617.1 - 0.18 12.1 1.3 0.61 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Methylase_S PF01420.14 EEA08617.1 - 3.8 7.4 9.1 7.8 6.4 0.4 3.2 2 1 1 3 3 3 0 Type I restriction modification DNA specificity domain Myb_DNA-binding PF00249.26 EEA08619.1 - 0.011 15.8 0.1 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mu-like_Com PF10122.4 EEA08619.1 - 0.015 14.3 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com MADF_DNA_bdg PF10545.4 EEA08619.1 - 0.097 12.8 0.5 0.097 12.8 0.3 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UCH PF00443.24 EEA08620.1 - 2.8e-21 75.8 0.1 3.5e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA08620.1 - 3.2e-06 26.7 0.7 8.4e-06 25.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4140 PF13600.1 EEA08621.1 - 0.0052 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) His_Phos_1 PF00300.17 EEA08622.1 - 2.7e-16 60.0 1.0 2.9e-16 59.9 0.7 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PadR PF03551.9 EEA08622.1 - 0.061 13.0 0.3 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TMF_TATA_bd PF12325.3 EEA08624.1 - 0.0044 16.7 0.8 0.82 9.4 0.0 2.1 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 EEA08624.1 - 0.1 12.4 4.7 0.13 12.0 3.1 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 EEA08624.1 - 0.16 11.8 3.4 4.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 EEA08624.1 - 0.41 10.4 6.3 1.2 8.9 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 EEA08624.1 - 0.47 10.5 4.5 8.1 6.5 3.1 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 EEA08624.1 - 0.53 10.1 3.9 13 5.6 0.1 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Flagellin_N PF00669.15 EEA08624.1 - 0.77 9.5 4.6 0.24 11.1 0.7 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region IncA PF04156.9 EEA08624.1 - 1.5 8.3 10.5 2.7 7.5 7.2 1.6 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 EEA08624.1 - 3.9 7.0 7.7 55 3.2 5.3 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF303 PF03629.13 EEA08625.1 - 2e-52 177.9 0.9 2.4e-52 177.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF303) Glyco_hydro_2_N PF02837.13 EEA08625.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Fip1 PF05182.8 EEA08629.1 - 2.2e-10 39.5 0.2 3.9e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Fip1 motif