# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Slp PF03843.13 XP_664812.1 - 0.044 13.1 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family His_Phos_1 PF00300.22 XP_664814.1 - 0.00037 20.2 0.0 0.0005 19.8 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) End3 PF12761.7 XP_664820.1 - 0.054 13.7 0.3 0.088 13.0 0.3 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 NB-ARC PF00931.22 XP_664821.1 - 0.064 12.4 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain Calcipressin PF04847.12 XP_664825.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Calcipressin HD_5 PF13487.6 XP_664829.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 HD domain AsnA PF03590.15 XP_664830.1 - 9e-64 215.3 4.4 1.2e-63 215.0 4.4 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase Choline_kin_N PF04428.14 XP_664830.1 - 0.069 12.8 0.1 0.069 12.8 0.1 2.3 3 0 0 3 3 3 0 Choline kinase N terminus DUF5624 PF18538.1 XP_664832.1 - 0.035 14.2 0.2 0.068 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) LapD_MoxY_N PF16448.5 XP_664832.1 - 0.35 10.7 1.8 1 9.2 0.1 2.2 1 1 0 2 2 2 0 LapD/MoxY periplasmic domain Phage_min_cap2 PF06152.11 XP_664832.1 - 1.5 7.6 6.7 1.7 7.5 1.0 2.2 2 0 0 2 2 2 0 Phage minor capsid protein 2 PTR PF12789.7 XP_664832.1 - 1.6 8.8 5.3 24 5.1 0.1 2.9 2 1 0 2 2 2 0 Phage tail repeat like Nucleoporin_FG PF13634.6 XP_664834.1 - 0.099 13.5 43.2 1.8e+03 -0.2 43.2 2.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region Tmemb_55A PF09788.9 XP_664836.1 - 2.1 7.3 3.4 3.6 6.6 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A CRAL_TRIO PF00650.20 XP_664837.1 - 5.1e-06 26.3 0.3 6.2e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain MRP-S33 PF08293.11 XP_664840.1 - 0.095 12.9 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 KAR9 PF08580.10 XP_664841.1 - 0.039 12.5 11.4 0.037 12.6 11.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.9 XP_664841.1 - 5.2 5.5 10.9 5.3 5.5 10.9 1.0 1 0 0 1 1 1 0 Macoilin family WD40_alt PF14077.6 XP_664842.1 - 0.19 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif CRAL_TRIO PF00650.20 XP_664844.1 - 2.8e-17 62.9 0.3 3.8e-17 62.4 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 XP_664844.1 - 0.059 13.5 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF4278 PF14105.6 XP_664847.1 - 0.067 13.6 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Lysyl_oxidase PF01186.17 XP_664848.1 - 0.0033 17.1 1.0 0.0034 17.1 1.0 1.1 1 0 0 1 1 1 1 Lysyl oxidase ChapFlgA PF13144.6 XP_664848.1 - 0.069 13.2 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Mo25 PF08569.11 XP_664851.1 - 6.4e-31 107.9 2.7 7.6e-31 107.7 2.7 1.0 1 0 0 1 1 1 1 Mo25-like KAsynt_C_assoc PF16197.5 XP_664852.1 - 0.00015 22.2 0.7 0.00029 21.3 0.5 1.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension NAGidase PF07555.13 XP_664852.1 - 0.045 13.1 3.5 0.65 9.3 0.1 2.1 1 1 1 2 2 2 0 beta-N-acetylglucosaminidase ATP-grasp_5 PF13549.6 XP_664852.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Consortin_C PF15281.6 XP_664854.1 - 0.078 13.0 0.3 0.24 11.4 0.2 1.9 1 1 0 1 1 1 0 Consortin C-terminus LIF_OSM PF01291.17 XP_664855.1 - 0.03 14.5 0.4 0.032 14.4 0.4 1.1 1 0 0 1 1 1 0 LIF / OSM family Paralemmin PF03285.15 XP_664855.1 - 0.042 13.4 3.2 0.047 13.3 3.2 1.0 1 0 0 1 1 1 0 Paralemmin Thioredoxin_16 PF18569.1 XP_664855.1 - 0.084 13.0 2.2 0.12 12.5 1.9 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain TRAPPC-Trs85 PF12739.7 XP_664858.1 - 0.014 14.4 0.9 0.018 14.1 0.9 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Atg14 PF10186.9 XP_664859.1 - 0.00036 19.7 2.6 0.00042 19.5 2.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tau95_N PF17682.1 XP_664862.1 - 6.7e-12 45.7 0.0 8.2e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Tau95 Triple barrel domain Cyclin_N PF00134.23 XP_664863.1 - 4.1e-07 29.8 0.1 5.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPC22 PF04573.12 XP_664865.1 - 4.8e-35 120.6 1.1 5.3e-35 120.4 1.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Runt PF00853.19 XP_664865.1 - 0.012 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Runt domain TAP42 PF04177.12 XP_664868.1 - 1.9e-09 37.1 1.5 2.3e-09 36.9 1.5 1.1 1 0 0 1 1 1 1 TAP42-like family PS-DH PF14765.6 XP_664869.1 - 0.00025 20.4 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase 7tm_1 PF00001.21 XP_664871.1 - 2.3 7.5 6.2 8.4 5.6 0.6 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4718 PF15842.5 XP_664872.1 - 0.013 15.3 1.9 0.015 15.1 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) EVI2A PF05399.11 XP_664874.1 - 4.2 6.9 6.6 0.37 10.4 1.9 1.5 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) TPR_17 PF13431.6 XP_664876.1 - 6.7e-05 23.0 0.1 0.0047 17.2 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat Peptidase_S66C PF17676.1 XP_664876.1 - 0.0016 19.0 0.0 0.0019 18.7 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain PPTA PF01239.22 XP_664876.1 - 0.0073 16.0 1.5 1.5 8.7 0.1 2.3 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 XP_664876.1 - 0.0085 16.8 0.0 1.3 10.0 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 XP_664876.1 - 0.044 12.8 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Cas_Cas02710 PF09670.10 XP_664876.1 - 0.088 11.6 0.1 0.1 11.4 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) TPR_2 PF07719.17 XP_664876.1 - 0.11 12.6 2.8 3.4 8.0 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxidored_q4 PF00507.19 XP_664876.1 - 0.21 11.8 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3960 PF13142.6 XP_664882.1 - 0.11 12.7 3.0 0.91 9.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3960) LAP1C PF05609.12 XP_664885.1 - 0.78 8.8 17.9 0.95 8.5 17.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 XP_664885.1 - 0.8 8.4 15.5 0.99 8.1 15.5 1.3 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 XP_664885.1 - 5.9 5.2 5.7 7.2 4.9 5.7 1.3 1 0 0 1 1 1 0 Membrane transport protein SOBP PF15279.6 XP_664885.1 - 6.8 7.2 6.9 8.2 6.9 6.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Acatn PF13000.7 XP_664886.1 - 6.3e-09 34.9 3.9 6.5e-09 34.8 3.9 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 DnaJ PF00226.31 XP_664887.1 - 0.0043 17.1 0.0 0.0054 16.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Keratin_2_head PF16208.5 XP_664887.1 - 0.93 9.6 15.4 1 9.5 15.4 1.1 1 0 0 1 1 1 0 Keratin type II head rRNA_processing PF08524.11 XP_664889.1 - 3.9e-10 39.9 16.9 4.5e-10 39.7 16.9 1.0 1 0 0 1 1 1 1 rRNA processing Mrr_N PF14338.6 XP_664889.1 - 0.026 14.7 1.4 0.18 11.9 0.2 2.2 1 1 1 2 2 2 0 Mrr N-terminal domain SMN PF06003.12 XP_664889.1 - 4.3 6.5 6.8 4.8 6.4 6.8 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Synaptobrevin PF00957.21 XP_664890.1 - 8.8e-20 70.3 1.7 8.8e-20 70.3 1.7 1.9 2 0 0 2 2 2 1 Synaptobrevin Ac110_PIF PF07280.11 XP_664890.1 - 6.1 6.7 7.7 0.6 9.9 0.5 2.3 2 0 0 2 2 2 0 Per os infectivity factor AC110 BioW PF03744.13 XP_664891.1 - 0.062 12.9 6.5 0.072 12.6 6.5 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase YbjN PF10722.9 XP_664891.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator FSIP1 PF15554.6 XP_664891.1 - 0.37 9.8 17.0 0.42 9.6 17.0 1.1 1 0 0 1 1 1 0 FSIP1 family 5-FTHF_cyc-lig PF01812.20 XP_664891.1 - 2.3 8.0 6.2 4.1 7.2 6.2 1.5 1 1 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Pkinase PF00069.25 XP_664892.1 - 5.6e-33 114.4 0.0 6.7e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_664892.1 - 4.6e-13 49.0 0.0 8.7e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_664892.1 - 1.6e-05 24.4 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DSRB PF10781.9 XP_664892.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB DUF3453 PF11935.8 XP_664896.1 - 0.024 14.3 8.2 1.8 8.2 3.7 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3453) CAP_C PF08603.11 XP_664897.1 - 2e-46 157.5 7.5 2.3e-46 157.3 7.5 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 XP_664897.1 - 5.1e-06 26.2 4.7 8.6e-06 25.5 4.7 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C WD40 PF00400.32 XP_664899.1 - 1.7e-17 63.5 6.3 1.1e-06 29.2 1.7 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_664899.1 - 1.1e-06 28.9 0.0 1.4 9.3 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 XP_664899.1 - 0.0001 20.8 0.1 0.00013 20.5 0.1 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 XP_664899.1 - 0.00052 19.1 0.0 0.00071 18.6 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 XP_664899.1 - 0.0034 16.0 0.1 0.0073 14.9 0.1 1.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 XP_664899.1 - 0.023 13.4 0.1 0.04 12.6 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 eIF2A PF08662.11 XP_664899.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A F_actin_cap_B PF01115.17 XP_664902.1 - 6.1e-26 91.5 21.1 1.4e-25 90.3 21.1 1.5 1 1 0 1 1 1 1 F-actin capping protein, beta subunit Kelch_3 PF13415.6 XP_664902.1 - 0.067 13.5 2.7 1.2 9.5 0.2 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 XP_664902.1 - 0.16 11.6 1.0 0.45 10.1 1.0 1.8 1 0 0 1 1 1 0 Kelch motif Corazonin PF17308.2 XP_664903.1 - 4.8 7.6 12.3 1.1 9.7 7.4 2.1 1 1 1 2 2 2 0 Pro-corazonin OB_NTP_bind PF07717.16 XP_664908.1 - 1.9e-16 60.2 0.9 3.8e-16 59.2 0.2 1.9 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Thioredoxin_11 PF18078.1 XP_664908.1 - 0.0077 16.3 11.2 0.44 10.7 0.4 2.2 1 1 1 2 2 2 2 Thioredoxin-like SNTX domain UPF0061 PF02696.14 XP_664908.1 - 0.011 14.6 4.8 0.013 14.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family C2 PF00168.30 XP_664912.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 C2 domain DUF5131 PF07505.11 XP_664914.1 - 0.052 13.0 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) DUF5442 PF17514.2 XP_664914.1 - 0.079 13.2 3.1 12 6.2 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5442) DUF4481 PF14800.6 XP_664915.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Phage_Nu1 PF07471.12 XP_664915.1 - 0.12 12.1 0.1 0.96 9.2 0.0 2.0 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Met_10 PF02475.16 XP_664916.1 - 4.2e-25 88.7 0.1 8e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DUF3642 PF12182.8 XP_664916.1 - 0.071 13.4 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 Bacterial lipoprotein Thioredoxin_13 PF18401.1 XP_664917.1 - 3.3e-06 27.0 0.1 7e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Atx10homo_assoc PF09759.9 XP_664917.1 - 0.026 14.5 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Mito_carr PF00153.27 XP_664919.1 - 2.8e-58 193.8 1.1 5.1e-27 93.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VASt PF16016.5 XP_664920.1 - 0.001 19.5 1.5 0.0037 17.7 0.2 2.3 2 1 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain DUF4205 PF13898.6 XP_664921.1 - 2.2e-11 43.3 0.0 3.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF3173 PF11372.8 XP_664921.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DEAD PF00270.29 XP_664922.1 - 1.4e-45 155.2 0.1 2.2e-45 154.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 XP_664922.1 - 6e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RICH PF05062.12 XP_664922.1 - 0.1 12.9 1.4 0.15 12.4 0.2 1.9 2 1 0 2 2 2 0 RICH domain DUF3510 PF12022.8 XP_664923.1 - 0.036 14.5 0.1 0.061 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Abi_2 PF07751.11 XP_664924.1 - 0.14 12.4 7.4 0.17 12.1 7.4 1.2 1 0 0 1 1 1 0 Abi-like protein RBP_receptor PF14752.6 XP_664924.1 - 0.93 8.0 2.8 1.1 7.8 2.8 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor Prenyltrans PF00432.21 XP_664926.1 - 1.3e-19 69.6 0.0 2.4e-08 33.6 0.0 3.9 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Coatomer_b_Cpla PF14806.6 XP_664928.1 - 1.5e-05 25.0 0.7 2.2e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform DUF5110 PF17137.4 XP_664929.1 - 0.032 14.5 1.6 0.032 14.5 1.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5110) PRKCSH_1 PF13015.6 XP_664929.1 - 0.75 9.5 5.4 0.18 11.5 0.6 2.2 1 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Pkinase PF00069.25 XP_664930.1 - 1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Orai-1 PF07856.12 XP_664931.1 - 0.053 13.2 0.3 0.053 13.2 0.3 1.8 1 1 1 2 2 2 0 Mediator of CRAC channel activity GTP_EFTU_D3 PF03143.17 XP_664933.1 - 2.9e-25 88.7 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 XP_664933.1 - 2.8e-05 24.4 0.0 5.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 IPPT PF01715.17 XP_664934.1 - 1.6e-07 31.4 0.0 1.7e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 IPP transferase GPS2_interact PF15784.5 XP_664934.1 - 0.064 13.7 0.2 0.072 13.5 0.2 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain AAA PF00004.29 XP_664935.1 - 4.6e-40 137.1 0.0 5.8e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 XP_664935.1 - 4.9e-08 33.3 0.0 8.2e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 XP_664935.1 - 1e-06 28.8 0.1 2.8e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 XP_664935.1 - 1.2e-06 28.9 0.9 0.00099 19.4 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 XP_664935.1 - 1.7e-06 28.5 0.3 2.9e-05 24.5 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 XP_664935.1 - 2.1e-05 24.4 0.1 4.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 XP_664935.1 - 0.00026 20.3 0.1 0.00067 19.0 0.0 1.7 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 XP_664935.1 - 0.00041 20.5 0.0 0.00055 20.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 XP_664935.1 - 0.00042 19.7 0.1 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 XP_664935.1 - 0.00082 19.1 0.1 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 XP_664935.1 - 0.0018 18.8 0.0 0.0026 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 XP_664935.1 - 0.0023 17.9 0.0 0.24 11.3 0.0 2.1 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 XP_664935.1 - 0.0023 17.3 0.0 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_664935.1 - 0.0026 17.6 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 XP_664935.1 - 0.0029 17.9 0.1 0.0066 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 XP_664935.1 - 0.0033 16.9 0.1 0.048 13.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.26 XP_664935.1 - 0.0035 17.1 0.2 0.032 13.9 0.0 2.4 1 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 XP_664935.1 - 0.0037 17.6 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 XP_664935.1 - 0.0047 16.9 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 XP_664935.1 - 0.0052 16.5 0.1 0.016 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 XP_664935.1 - 0.0081 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 XP_664935.1 - 0.0095 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 XP_664935.1 - 0.011 15.3 0.1 0.063 12.9 0.1 1.9 1 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 XP_664935.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 XP_664935.1 - 0.029 13.5 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 XP_664935.1 - 0.034 14.6 0.1 0.063 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 XP_664935.1 - 0.039 13.2 0.0 0.079 12.2 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 XP_664935.1 - 0.069 12.9 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 XP_664935.1 - 0.075 13.1 0.0 0.34 11.0 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 XP_664935.1 - 0.076 13.5 0.0 0.11 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 XP_664935.1 - 0.084 13.2 0.2 0.19 12.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 XP_664935.1 - 0.088 12.0 0.0 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 XP_664935.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 XP_664935.1 - 0.17 11.8 0.0 0.71 9.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Crinivirus_P26 PF07416.11 XP_664937.1 - 0.02 14.6 0.6 0.036 13.8 0.1 1.5 2 0 0 2 2 2 0 Crinivirus P26 protein Spatacsin_C PF14649.6 XP_664938.1 - 0.00011 21.4 0.2 0.00056 19.1 0.2 2.0 1 1 0 1 1 1 1 Spatacsin C-terminus YozE_SAM_like PF06855.12 XP_664939.1 - 0.11 12.7 2.2 2.1 8.6 0.5 2.9 2 0 0 2 2 2 0 YozE SAM-like fold Pkinase PF00069.25 XP_664940.1 - 4.6e-43 147.5 0.0 5.8e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_664940.1 - 1e-09 38.1 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 XP_664940.1 - 1e-06 28.9 0.1 4e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 XP_664940.1 - 0.0049 16.5 0.5 0.041 13.5 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 XP_664940.1 - 0.02 13.7 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 XP_664940.1 - 0.026 13.9 0.2 0.038 13.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 XP_664941.1 - 6.9e-09 35.5 3.0 0.0002 20.8 0.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_664941.1 - 9.2e-06 25.1 0.7 0.017 14.4 0.3 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase PglD_N PF17836.1 XP_664941.1 - 0.027 15.1 0.4 0.052 14.2 0.4 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Imm43 PF15570.6 XP_664941.1 - 0.82 9.7 10.6 1.2 9.1 6.9 2.3 1 1 0 2 2 2 0 Immunity protein 43 YlbD_coat PF14071.6 XP_664942.1 - 5.2 7.3 10.8 3.1 8.1 4.3 2.6 2 2 0 2 2 2 0 Putative coat protein DUF1600 PF07667.11 XP_664943.1 - 0.17 12.1 5.7 0.48 10.7 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Gloverin PF10793.9 XP_664944.1 - 0.0073 16.2 0.1 0.0084 16.0 0.1 1.1 1 0 0 1 1 1 1 Gloverin-like protein Phage_C PF12025.8 XP_664946.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phage protein C RhoGEF67_u2 PF16614.5 XP_664946.1 - 0.66 10.1 2.6 5.8 7.0 1.0 2.2 1 1 1 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Presenilin PF01080.17 XP_664946.1 - 3.7 6.2 7.1 4.4 6.0 7.1 1.0 1 0 0 1 1 1 0 Presenilin MRNIP PF15749.5 XP_664946.1 - 4.6 8.0 12.3 12 6.7 12.3 1.6 1 1 0 1 1 1 0 MRN-interacting protein DUF1836 PF08876.11 XP_664947.1 - 0.11 12.5 6.4 0.054 13.6 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) DUF4907 PF16250.5 XP_664947.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) FPL PF09758.9 XP_664948.1 - 4.9e-25 88.3 5.2 6.5e-25 87.9 5.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Mannosyl_trans2 PF04188.13 XP_664949.1 - 1.3e-11 44.5 22.8 1.5e-11 44.3 22.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 XP_664951.1 - 4.2e-06 25.7 1.0 1.1e-05 24.4 1.0 1.7 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region ATP-synt_ab_N PF02874.23 XP_664952.1 - 1.3e-13 51.3 0.7 2.6e-13 50.3 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 XP_664952.1 - 7.6e-13 48.6 0.1 1.7e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 XP_664952.1 - 0.033 13.6 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 KaiC Cad PF03596.13 XP_664952.1 - 0.048 13.5 0.6 11 5.9 0.1 2.4 1 1 1 2 2 2 0 Cadmium resistance transporter AAA_14 PF13173.6 XP_664952.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb2_6 PF00562.28 XP_664954.1 - 6.1e-108 361.4 0.0 6.8e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 AAA_8 PF12780.7 XP_664960.1 - 6.6e-36 124.0 0.0 9.2e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA PF00004.29 XP_664960.1 - 5.9e-08 33.2 0.0 3.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 XP_664960.1 - 6.6e-05 22.9 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 XP_664960.1 - 0.00046 19.6 1.4 0.0033 16.8 0.2 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 XP_664960.1 - 0.00067 20.1 0.0 0.0027 18.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 XP_664960.1 - 0.001 19.4 0.0 0.013 15.7 0.0 2.4 1 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 XP_664960.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 XP_664960.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 XP_664960.1 - 0.11 12.5 0.0 3.5 7.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 XP_664960.1 - 0.12 13.0 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 XP_664960.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 XP_664960.1 - 0.18 11.9 0.0 6.7 6.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sulfotransfer_1 PF00685.27 XP_664960.1 - 0.22 11.0 0.0 14 5.0 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase domain Claudin_3 PF06653.11 XP_664961.1 - 0.001 19.1 2.4 0.0011 18.9 2.4 1.0 1 0 0 1 1 1 1 Tight junction protein, Claudin-like KASH_CCD PF14662.6 XP_664962.1 - 0.013 15.3 16.8 0.084 12.7 7.7 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 XP_664962.1 - 0.015 15.4 3.5 0.015 15.4 3.5 3.2 2 1 0 2 2 2 0 bZIP transcription factor Caprin-1_dimer PF18293.1 XP_664962.1 - 0.041 14.4 2.7 2.7 8.5 1.3 3.0 2 1 0 2 2 2 0 Caprin-1 dimerization domain BLOC1_2 PF10046.9 XP_664962.1 - 0.056 13.7 1.7 0.056 13.7 1.7 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 XP_664962.1 - 0.26 12.0 15.0 0.34 11.6 4.7 3.0 2 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 XP_664962.1 - 0.28 11.5 0.2 0.28 11.5 0.2 3.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper FapA PF03961.13 XP_664962.1 - 0.66 8.5 15.1 0.33 9.5 1.6 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A IKKbetaNEMObind PF12179.8 XP_664962.1 - 0.79 9.8 4.6 0.29 11.2 0.7 2.4 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain ADIP PF11559.8 XP_664962.1 - 1 9.5 18.9 0.55 10.3 1.3 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.13 XP_664962.1 - 1.3 9.8 17.5 1.5 9.6 1.2 3.7 2 2 1 3 3 3 0 Occludin homology domain PRANC PF09372.10 XP_664962.1 - 2.6 8.4 8.0 2.7 8.4 0.7 2.8 2 0 0 2 2 2 0 PRANC domain FERM_M PF00373.18 XP_664962.1 - 6.8 7.1 6.8 36 4.8 3.9 2.8 2 1 0 2 2 2 0 FERM central domain Fib_alpha PF08702.10 XP_664962.1 - 8 6.6 15.6 6.1 7.0 7.7 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IKKbetaNEMObind PF12179.8 XP_664963.1 - 0.019 15.0 1.5 0.066 13.3 0.4 2.5 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain GDI PF00996.18 XP_664964.1 - 3.8e-164 546.3 0.1 4.3e-164 546.2 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Arm_vescicular PF18770.1 XP_664964.1 - 0.011 15.6 0.4 0.028 14.3 0.1 1.8 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor NAD_binding_8 PF13450.6 XP_664964.1 - 0.075 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 XP_664964.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain COMM_domain PF07258.14 XP_664965.1 - 0.013 15.6 1.9 0.025 14.7 0.3 2.2 2 0 0 2 2 2 0 COMM domain Thioredoxin_12 PF18400.1 XP_664966.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain MRP-S33 PF08293.11 XP_664966.1 - 0.04 14.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Met_gamma_lyase PF06838.11 XP_664966.1 - 0.18 10.3 0.5 1.2 7.6 0.3 1.9 2 0 0 2 2 2 0 Methionine gamma-lyase DUF5412 PF17428.2 XP_664968.1 - 0.18 11.7 1.2 3.9 7.4 0.0 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5412) WD40 PF00400.32 XP_664972.1 - 5.2e-20 71.4 13.2 0.0036 18.1 0.3 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Sof1 PF04158.14 XP_664972.1 - 1.5e-18 66.9 1.6 2.7e-18 66.0 1.6 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 XP_664972.1 - 1.1e-06 28.8 0.1 0.79 10.1 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 XP_664972.1 - 0.00037 20.5 0.1 2.9 8.0 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 XP_664972.1 - 0.018 14.4 0.0 7.4 5.8 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain Ribosomal_L28e PF01778.17 XP_664973.1 - 2.9e-22 79.6 5.7 3.4e-22 79.4 5.7 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family PuR_N PF09182.10 XP_664973.1 - 0.0019 18.1 0.3 1.4 8.9 0.1 2.2 1 1 1 2 2 2 2 Bacterial purine repressor, N-terminal UcrQ PF02939.16 XP_664974.1 - 0.046 13.6 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 UcrQ family CBM_25 PF03423.13 XP_664976.1 - 0.3 11.3 6.0 1 9.7 0.4 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) DUF4611 PF15387.6 XP_664978.1 - 0.024 14.8 15.9 0.14 12.4 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 XP_664978.1 - 0.093 12.4 9.3 1.4 8.6 1.1 2.3 2 0 0 2 2 2 0 FAM176 family HsdM_N PF12161.8 XP_664978.1 - 0.11 13.1 9.1 0.22 12.1 9.1 1.5 1 0 0 1 1 1 0 HsdM N-terminal domain CENP-B_dimeris PF09026.10 XP_664978.1 - 3.1 8.2 16.8 1.4 9.4 5.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4834 PF16118.5 XP_664979.1 - 1.8 9.6 11.4 12 6.9 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Renin_r PF07850.14 XP_664979.1 - 2.1 9.0 5.3 8.9 7.0 5.3 2.2 1 1 0 1 1 1 0 Renin receptor-like protein Cwf_Cwc_15 PF04889.12 XP_664982.1 - 1.6e-23 83.7 33.4 6.9e-22 78.4 33.4 2.1 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF413 PF04219.12 XP_664982.1 - 2.5 8.2 6.9 0.44 10.6 1.9 2.2 3 0 0 3 3 3 0 Protein of unknown function, DUF APG6 PF04111.12 XP_664983.1 - 1.6e-32 112.9 0.4 5.8e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Apg6 BARA domain VOMI PF03762.17 XP_664984.1 - 0.28 11.3 4.7 0.56 10.3 0.4 2.9 1 1 1 3 3 3 0 Vitelline membrane outer layer protein I (VOMI) FCH PF00611.23 XP_664985.1 - 0.0092 16.3 0.3 0.037 14.3 0.0 2.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain YolD PF08863.10 XP_664985.1 - 0.017 15.2 4.7 0.019 15.0 2.5 2.2 1 1 1 2 2 2 0 YolD-like protein HycH PF07450.11 XP_664985.1 - 0.026 14.9 0.8 0.036 14.4 0.8 1.3 1 1 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH DASH_Dad4 PF08650.10 XP_664985.1 - 0.035 14.1 6.9 2.2 8.3 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 FliJ PF02050.16 XP_664985.1 - 0.39 11.0 5.0 2.8 8.2 0.2 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein His_Phos_2 PF00328.22 XP_664986.1 - 6.9e-15 55.3 0.5 9.6e-15 54.8 0.5 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TatD_DNase PF01026.21 XP_664988.1 - 4.4e-11 42.7 0.0 4.9e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Ham1p_like PF01725.16 XP_664989.1 - 1.1e-10 41.8 0.0 1.1e-10 41.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family CUTL PF16557.5 XP_664990.1 - 0.26 11.5 4.6 0.29 11.3 0.1 2.8 2 1 1 3 3 3 0 CUT1-like DNA-binding domain of SATB DUF1465 PF07323.12 XP_664991.1 - 0.16 11.8 5.5 0.048 13.5 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) HAUS-augmin3 PF14932.6 XP_664991.1 - 0.16 11.5 17.2 0.014 14.9 11.8 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 XP_664991.1 - 1.6 8.1 25.1 2.2 7.7 25.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATP-synt_ab_C PF00306.27 XP_664992.1 - 0.065 13.6 0.2 0.17 12.2 0.1 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain CTP_transf_1 PF01148.20 XP_664993.1 - 7.8e-58 196.3 4.9 9.2e-58 196.1 4.9 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family CitMHS PF03600.16 XP_664993.1 - 0.059 12.6 0.3 0.11 11.6 0.3 1.5 1 0 0 1 1 1 0 Citrate transporter Pox_A31 PF05771.11 XP_664994.1 - 0.0026 17.8 1.1 0.011 15.8 0.2 2.2 2 0 0 2 2 2 1 Poxvirus A31 protein Bromodomain PF00439.25 XP_664995.1 - 7.6e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Aa_trans PF01490.18 XP_664997.1 - 2.7e-16 59.3 29.6 3.3e-16 59.0 29.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Got1 PF04178.12 XP_665002.1 - 4e-15 56.2 2.3 4.8e-15 56.0 2.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PALP PF00291.25 XP_665003.1 - 2.8e-38 132.0 0.0 3.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SM-ATX PF14438.6 XP_665003.1 - 0.14 12.3 0.5 2.5 8.3 0.0 3.0 4 0 0 4 4 4 0 Ataxin 2 SM domain GMP_synt_C PF00958.22 XP_665005.1 - 7.5e-06 25.9 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 GMP synthase C terminal domain Headcase PF16002.5 XP_665005.1 - 0.037 13.5 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Headcase protein AlphaC_C PF17480.2 XP_665006.1 - 0.024 14.6 3.1 0.078 13.0 3.1 1.9 1 0 0 1 1 1 0 AlphaC C-terminal Fcf1 PF04900.12 XP_665011.1 - 2.3e-23 82.4 0.5 5.3e-14 52.4 0.0 2.2 1 1 1 2 2 2 2 Fcf1 Pro-MCH PF05824.12 XP_665011.1 - 0.006 16.5 0.6 0.021 14.7 0.5 1.9 1 1 1 2 2 2 1 Pro-melanin-concentrating hormone (Pro-MCH) dsRBD2 PF17842.1 XP_665011.1 - 0.084 13.1 0.7 0.13 12.4 0.7 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 zf-RING_UBOX PF13445.6 XP_665011.1 - 0.087 12.9 0.2 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger GCV_T_C PF08669.11 XP_665012.1 - 2.2e-05 24.3 0.0 8.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain ALMT PF11744.8 XP_665014.1 - 0.4 9.4 3.3 0.51 9.1 3.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 XP_665014.1 - 8 4.9 12.4 9 4.7 12.4 1.0 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 XP_665015.1 - 1.2e-07 32.3 0.9 0.0051 17.6 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665015.1 - 2.6e-06 27.7 0.0 0.00036 20.8 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 XP_665015.1 - 0.00089 18.1 1.1 1.9 7.1 0.0 3.0 1 1 2 3 3 3 3 Nup133 N terminal like Baculo_IE-1 PF05290.11 XP_665016.1 - 0.028 14.3 0.5 1.1 9.2 0.4 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) YpjP PF14005.6 XP_665017.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.0 3 0 0 3 3 3 0 YpjP-like protein CorA PF01544.18 XP_665019.1 - 0.00069 19.0 3.2 0.00074 18.9 3.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MgtE PF01769.16 XP_665019.1 - 0.098 13.0 3.8 0.098 13.0 3.8 1.1 1 0 0 1 1 1 0 Divalent cation transporter DUF2207 PF09972.9 XP_665019.1 - 0.8 8.4 3.6 0.92 8.2 3.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Brix PF04427.18 XP_665021.1 - 8.9e-38 130.3 0.3 1.3e-37 129.8 0.3 1.4 1 0 0 1 1 1 1 Brix domain DUF5598 PF18127.1 XP_665022.1 - 0.018 15.5 0.6 0.095 13.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) Ca_bind_SSO6904 PF18249.1 XP_665022.1 - 1.8 8.9 11.9 0.22 11.9 0.2 4.4 2 1 3 5 5 5 0 Calcium binding protein SSO6904 Peptidase_M54 PF07998.11 XP_665023.1 - 5.4e-17 62.4 3.3 6.6e-17 62.1 3.3 1.1 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_5 PF13688.6 XP_665023.1 - 0.016 15.4 0.7 0.03 14.5 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 XP_665023.1 - 0.017 15.6 0.2 0.028 14.9 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2268 PF10026.9 XP_665023.1 - 0.027 14.0 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M10 PF00413.24 XP_665023.1 - 0.034 14.0 0.5 0.051 13.4 0.5 1.4 1 1 0 1 1 1 0 Matrixin SecM PF06558.12 XP_665024.1 - 0.029 14.4 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) XRN_N PF03159.18 XP_665025.1 - 1.1e-56 192.0 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SUV3_C PF12513.8 XP_665025.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal DNA_ligase_A_N PF04675.14 XP_665026.1 - 6.9e-35 120.9 0.3 1.1e-34 120.3 0.3 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DUF3291 PF11695.8 XP_665027.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) DUF4554 PF15091.6 XP_665028.1 - 2.7 6.8 6.9 3.3 6.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) ERM PF00769.19 XP_665028.1 - 4.3 7.1 38.3 30 4.3 38.3 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF5401 PF17380.2 XP_665028.1 - 5.9 4.8 36.3 7 4.6 36.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Trep_dent_lipo PF09710.10 XP_665028.1 - 6.7 5.5 15.9 2.5 6.9 13.5 1.4 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Spb1_C PF07780.12 XP_665029.1 - 7.1e-49 166.3 21.5 9.8e-49 165.8 21.5 1.2 1 0 0 1 1 1 1 Spb1 C-terminal domain Citrate_ly_lig PF08218.11 XP_665029.1 - 0.032 13.9 1.3 0.043 13.5 0.5 1.6 1 1 0 1 1 1 0 Citrate lyase ligase C-terminal domain DNA_primase_S PF01896.19 XP_665030.1 - 4.5e-18 65.9 0.1 1.1e-17 64.7 0.0 1.7 2 0 0 2 2 2 1 DNA primase small subunit RIBIOP_C PF04950.12 XP_665031.1 - 2.9e-34 118.8 1.6 2.9e-34 118.8 1.6 2.0 2 1 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PUB PF09409.10 XP_665032.1 - 0.001 19.0 0.5 0.001 19.0 0.5 1.9 2 0 0 2 2 2 1 PUB domain Orbi_VP2 PF00898.17 XP_665032.1 - 0.057 11.2 0.7 0.3 8.8 0.0 1.9 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP2 DSPc PF00782.20 XP_665032.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TFIIE_beta PF02186.15 XP_665037.1 - 0.34 11.2 4.3 14 6.0 0.2 3.5 2 1 1 3 3 3 0 TFIIE beta subunit core domain NADHdh_A3 PF14987.6 XP_665038.1 - 0.034 14.4 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 ABC_membrane PF00664.23 XP_665039.1 - 8.1e-07 29.0 12.9 1.5e-06 28.1 12.9 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region PAP_RNA-bind PF04926.15 XP_665040.1 - 6.6e-14 51.9 3.9 9.4e-08 31.9 0.0 3.4 1 1 2 3 3 3 2 Poly(A) polymerase predicted RNA binding domain Glycoprot_B_PH2 PF17417.2 XP_665040.1 - 1.9 8.9 9.8 0.23 11.8 3.2 2.6 1 1 2 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain Glu_cyclase_2 PF05096.12 XP_665041.1 - 3.7e-45 154.3 0.0 7.3e-45 153.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine cyclotransferase DUF1449 PF07290.11 XP_665042.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Adeno_E3_CR2 PF02439.15 XP_665042.1 - 4.1 7.3 7.1 5.6 6.8 7.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gemini_AL1_M PF08283.11 XP_665043.1 - 0.094 12.8 0.0 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 Geminivirus rep protein central domain SIR2 PF02146.17 XP_665044.1 - 0.03 14.3 0.6 0.056 13.4 0.6 1.6 1 1 0 1 1 1 0 Sir2 family Helicase_C PF00271.31 XP_665044.1 - 4.3 7.7 10.1 2.2 8.7 1.1 3.2 1 1 0 3 3 3 0 Helicase conserved C-terminal domain PWI PF01480.17 XP_665049.1 - 0.014 15.7 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 PWI domain PP1_inhibitor PF05361.12 XP_665049.1 - 0.035 14.1 0.3 0.04 13.9 0.3 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor DUF3910 PF13049.6 XP_665049.1 - 0.045 14.1 0.1 0.054 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Helicase_C PF00271.31 XP_665051.1 - 0.0041 17.5 0.1 0.0078 16.6 0.1 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain TMEM95 PF15203.6 XP_665052.1 - 0.1 12.3 0.6 0.3 10.7 0.6 1.8 1 0 0 1 1 1 0 TMEM95 family DUF2935 PF11155.8 XP_665052.1 - 0.19 12.1 12.3 3.2 8.1 5.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Zein-binding PF04576.15 XP_665052.1 - 0.44 10.8 0.1 0.44 10.8 0.1 3.6 4 1 0 4 4 4 0 Zein-binding DUF1465 PF07323.12 XP_665052.1 - 0.77 9.6 4.8 2.8 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) ATG16 PF08614.11 XP_665052.1 - 1.8 8.8 17.9 0.35 11.1 2.3 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) UPF0020 PF01170.18 XP_665053.1 - 0.049 13.3 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 INTAP PF16617.5 XP_665054.1 - 0.19 12.1 3.2 0.38 11.1 3.2 1.5 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region E1-E2_ATPase PF00122.20 XP_665055.1 - 4.5e-29 101.2 0.7 5.9e-29 100.9 0.7 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Peptidase_C13 PF01650.18 XP_665055.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase C13 family Peptidase_S24 PF00717.23 XP_665056.1 - 0.044 13.7 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase S24-like XPA_C PF05181.12 XP_665057.1 - 3e-05 23.9 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus DUF3347 PF11827.8 XP_665057.1 - 0.082 13.1 4.7 0.098 12.8 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) MICSWaP PF17018.5 XP_665057.1 - 1.2 8.6 6.4 0.46 10.0 1.4 2.0 1 1 1 2 2 2 0 Spore wall protein JAB PF01398.21 XP_665058.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Kinesin PF00225.23 XP_665059.1 - 8.8e-09 34.7 0.1 1.5e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 XP_665059.1 - 0.007 16.3 1.1 0.063 13.2 0.2 2.5 2 1 0 2 2 2 1 Microtubule binding Atx10homo_assoc PF09759.9 XP_665063.1 - 0.00035 20.5 1.6 0.0036 17.3 0.2 2.6 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RT_RNaseH PF17917.1 XP_665064.1 - 0.054 13.8 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase tRNA_bind PF01588.20 XP_665065.1 - 1.8e-26 92.1 0.0 3.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 XP_665065.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 XP_665065.1 - 0.0026 17.5 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 XP_665065.1 - 0.041 14.1 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 XP_665065.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NopRA1 PF16201.5 XP_665067.1 - 3.7e-17 62.6 2.4 1.8e-15 57.1 0.9 2.4 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Nop14 PF04147.12 XP_665067.1 - 0.0012 17.2 18.9 0.0012 17.2 18.9 2.0 2 0 0 2 2 2 1 Nop14-like family DUF913 PF06025.12 XP_665067.1 - 0.0036 16.3 5.8 0.64 8.9 5.9 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) ETRAMP PF09716.10 XP_665067.1 - 0.12 12.4 6.3 34 4.6 0.0 4.5 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Presenilin PF01080.17 XP_665067.1 - 0.27 9.9 13.6 0.078 11.7 9.4 2.0 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 XP_665067.1 - 0.8 7.9 28.2 0.06 11.6 20.5 2.1 2 0 0 2 2 2 0 CDC45-like protein CLN3 PF02487.17 XP_665067.1 - 0.91 8.5 16.9 0.12 11.3 4.0 2.3 2 0 0 2 2 2 0 CLN3 protein Mem_trans PF03547.18 XP_665067.1 - 2.3 6.5 3.7 5.3 5.3 3.7 1.6 1 0 0 1 1 1 0 Membrane transport protein Serinc PF03348.15 XP_665067.1 - 6.2 5.6 8.8 0.91 8.4 2.5 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF5357 PF17310.2 XP_665069.1 - 0.048 12.2 0.1 0.62 8.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5357) DUF771 PF05595.11 XP_665070.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF771) DUF2633 PF11119.8 XP_665070.1 - 2.3 8.2 5.0 3.8 7.5 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Kazal_1 PF00050.21 XP_665071.1 - 5.7e-09 35.9 3.3 1e-08 35.0 3.3 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 XP_665071.1 - 1.2e-06 28.6 3.4 2e-06 27.8 3.4 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PAP1 PF08601.10 XP_665071.1 - 0.42 10.3 17.7 0.62 9.7 17.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 XP_665071.1 - 7.2 5.0 10.7 8.8 4.7 10.7 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 XP_665072.1 - 7.8e-05 21.1 11.4 0.00011 20.6 11.4 1.4 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.17 XP_665072.1 - 0.079 12.9 31.2 0.12 12.4 31.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 XP_665072.1 - 0.12 12.3 20.1 0.24 11.4 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 XP_665072.1 - 0.29 9.2 15.5 0.38 8.8 15.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM100 PF16311.5 XP_665074.1 - 0.078 12.6 0.4 0.084 12.5 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 RRM_1 PF00076.22 XP_665075.1 - 5.4e-17 61.4 0.8 1.3e-16 60.2 0.4 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 XP_665075.1 - 4.2e-06 27.2 0.3 4.2e-06 27.2 0.3 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G L_lac_phage_MSP PF06488.11 XP_665075.1 - 0.012 14.9 0.4 0.025 13.9 0.4 1.5 1 0 0 1 1 1 0 Phage tail tube protein AGOG PF09171.10 XP_665075.1 - 0.039 13.3 0.2 0.072 12.4 0.2 1.4 1 0 0 1 1 1 0 N-glycosylase/DNA lyase ComGF PF15980.5 XP_665075.1 - 0.075 13.4 0.2 0.075 13.4 0.2 2.8 2 1 0 2 2 2 0 Putative Competence protein ComGF RRM_7 PF16367.5 XP_665075.1 - 0.091 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif ASF1_hist_chap PF04729.13 XP_665078.1 - 4.2e-39 134.0 0.0 6.6e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone ArlS_N PF18719.1 XP_665079.1 - 0.64 10.2 12.1 0.96 9.7 2.2 2.4 2 1 0 2 2 2 0 ArlS sensor domain Helicase_C PF00271.31 XP_665080.1 - 1.1e-21 77.2 0.0 2.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 XP_665080.1 - 1.4e-18 66.9 0.4 3.3e-18 65.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RNA_polI_A14 PF08203.11 XP_665081.1 - 1.6 9.5 4.3 6.3 7.6 0.4 3.1 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Peptidase_S49_N PF08496.10 XP_665081.1 - 1.8 8.6 5.9 27 4.8 3.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_C14 PF00656.22 XP_665082.1 - 9.2e-31 107.7 0.0 7.1e-30 104.8 0.0 2.1 2 0 0 2 2 2 1 Caspase domain Autophagy_N PF03986.13 XP_665084.1 - 0.045 13.7 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain PH PF00169.29 XP_665084.1 - 0.067 13.7 0.1 0.067 13.7 0.1 2.7 3 1 0 3 3 3 0 PH domain RRN3 PF05327.11 XP_665085.1 - 7e-08 31.5 1.5 1.5e-07 30.4 1.5 1.5 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 LisH_TPL PF17814.1 XP_665086.1 - 2.7e-05 23.7 3.1 3e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 LisH-like dimerisation domain FokI_N PF02981.15 XP_665088.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain DUF5427 PF10310.9 XP_665088.1 - 0.37 9.7 2.4 0.44 9.5 2.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) VTC PF09359.10 XP_665089.1 - 1.6e-98 329.5 6.3 1.9e-98 329.3 3.2 2.2 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 XP_665089.1 - 0.00016 22.1 0.6 0.00016 22.1 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1282 PF06930.12 XP_665089.1 - 0.0025 17.6 0.3 0.0049 16.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) zf-C2H2_2 PF12756.7 XP_665090.1 - 1e-05 25.8 1.8 1.4e-05 25.4 1.8 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 XP_665090.1 - 0.003 18.3 0.3 0.0062 17.3 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-UBP PF02148.19 XP_665090.1 - 0.0037 17.5 0.1 0.0048 17.2 0.1 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.26 XP_665090.1 - 0.053 14.0 0.4 0.14 12.7 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-SCNM1 PF15803.5 XP_665090.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.0 3 0 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 FHA PF00498.26 XP_665091.1 - 1e-14 54.6 0.2 2.6e-14 53.3 0.2 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 XP_665091.1 - 0.00063 20.0 0.0 0.0035 17.6 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4394 PF14339.6 XP_665091.1 - 0.012 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Glyco_hydro_43 PF04616.14 XP_665091.1 - 0.056 12.8 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 GAS PF13851.6 XP_665092.1 - 0.059 12.7 32.4 0.015 14.7 13.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 XP_665092.1 - 0.76 10.3 27.1 1.1 9.7 0.3 4.1 4 0 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Golgin_A5 PF09787.9 XP_665092.1 - 0.94 8.9 31.1 0.23 10.9 10.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 PRKG1_interact PF15898.5 XP_665092.1 - 1 10.3 27.9 2 9.3 4.5 3.2 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 XP_665092.1 - 2.1 8.2 23.6 1.9 8.3 0.4 4.0 3 1 1 4 4 4 0 Septum formation initiator Tropomyosin_1 PF12718.7 XP_665092.1 - 6 7.0 30.1 0.48 10.6 0.7 2.3 1 1 1 2 2 2 0 Tropomyosin like JIP_LZII PF16471.5 XP_665092.1 - 6.6 7.0 25.9 3.7 7.8 2.5 4.4 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II UL41A PF17591.2 XP_665093.1 - 0.039 14.0 1.4 0.071 13.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A CBM_20 PF00686.19 XP_665094.1 - 6.8e-21 74.0 2.0 9.6e-21 73.5 2.0 1.2 1 0 0 1 1 1 1 Starch binding domain EFG_C PF00679.24 XP_665096.1 - 2.7e-19 69.0 0.0 3.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor G C-terminus Rdx PF10262.9 XP_665097.1 - 1.3e-08 34.9 0.0 2.1e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Rdx family AAA_assoc PF14363.6 XP_665097.1 - 0.038 14.3 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA NOB1_Zn_bind PF08772.11 XP_665097.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF3918 PF13056.6 XP_665097.1 - 0.2 11.3 0.4 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) IF-2B PF01008.17 XP_665098.1 - 0.072 12.3 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family PMI_typeI PF01238.21 XP_665100.1 - 1.1e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I mCpol PF18182.1 XP_665100.1 - 0.0062 16.8 0.8 1.6 9.1 0.2 2.1 1 1 1 2 2 2 2 minimal CRISPR polymerase domain C2 PF00168.30 XP_665102.1 - 0.032 14.5 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 C2 domain Dpy19 PF10034.9 XP_665103.1 - 1.1e-114 384.0 34.3 1.4e-114 383.7 34.3 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation KNOX1 PF03790.13 XP_665103.1 - 0.18 11.6 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 KNOX1 domain RNase_PH PF01138.21 XP_665105.1 - 9.4e-18 65.0 0.1 1.1e-17 64.8 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PPI_Ypi1 PF07491.11 XP_665106.1 - 1e-18 66.9 14.2 1e-18 66.9 14.2 2.5 1 1 1 2 2 2 1 Protein phosphatase inhibitor AF-4 PF05110.13 XP_665106.1 - 0.0024 16.0 13.9 0.0029 15.8 13.9 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein IBB PF01749.20 XP_665106.1 - 0.27 11.7 5.5 0.53 10.8 0.3 2.3 2 0 0 2 2 2 0 Importin beta binding domain SEEEED PF14797.6 XP_665106.1 - 1.8 8.7 24.6 3.5 7.8 24.6 1.5 1 1 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex CEP63 PF17045.5 XP_665109.1 - 0.0014 18.6 12.7 0.15 12.0 2.5 2.3 2 0 0 2 2 2 2 Centrosomal protein of 63 kDa THP2 PF09432.10 XP_665109.1 - 0.02 14.9 2.0 0.02 14.9 2.0 2.0 2 0 0 2 2 2 0 Tho complex subunit THP2 Acetyltransf_11 PF13720.6 XP_665109.1 - 0.044 14.2 2.8 0.053 14.0 0.2 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Urocanase PF01175.18 XP_665109.1 - 0.1 12.3 0.6 0.22 11.2 0.6 1.5 1 1 0 1 1 1 0 Urocanase Rossmann-like domain Bap31_Bap29_C PF18035.1 XP_665109.1 - 0.15 12.1 0.1 0.15 12.1 0.1 3.9 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF641 PF04859.12 XP_665109.1 - 0.92 9.9 14.0 0.55 10.6 4.4 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 XP_665109.1 - 1.9 7.8 11.1 0.12 11.7 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FliJ PF02050.16 XP_665109.1 - 1.9 8.7 18.3 1.4 9.2 5.4 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein HIP1_clath_bdg PF16515.5 XP_665109.1 - 3.7 8.2 18.7 0.13 12.9 5.3 2.9 2 2 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 XP_665109.1 - 6.5 7.4 9.6 4.2 8.1 2.9 3.1 2 1 1 3 3 3 0 SlyX Troponin PF00992.20 XP_665109.1 - 6.7 7.0 12.1 3.6 7.9 5.9 2.3 2 0 0 2 2 2 0 Troponin HlyD_D23 PF16576.5 XP_665110.1 - 0.14 11.4 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Patatin PF01734.22 XP_665111.1 - 1.5e-10 41.6 1.0 6.2e-09 36.3 1.0 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase Sel1 PF08238.12 XP_665112.1 - 1.9e-12 47.4 9.8 0.0014 19.3 0.6 4.7 4 0 0 4 4 4 3 Sel1 repeat PBP1_TM PF14812.6 XP_665112.1 - 0.3 11.5 3.6 0.71 10.3 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VHL_C PF17211.3 XP_665113.1 - 0.31 11.1 2.4 2.2 8.4 0.3 2.6 2 0 0 2 2 2 0 VHL box domain COX16 PF14138.6 XP_665113.1 - 0.72 10.4 0.0 0.72 10.4 0.0 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 PUB PF09409.10 XP_665114.1 - 8.5e-25 86.5 0.3 1.5e-23 82.5 0.1 2.5 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 XP_665114.1 - 5.2e-05 23.0 0.1 0.00037 20.3 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Ribonuc_red_sm PF00268.21 XP_665115.1 - 3.7e-103 344.8 1.2 4.3e-103 344.6 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain EMC1_C PF07774.13 XP_665117.1 - 1.9e-24 86.5 8.0 3.3e-24 85.8 8.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal DUF3685 PF12452.8 XP_665117.1 - 0.029 14.1 0.5 0.061 13.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF4500 PF14937.6 XP_665117.1 - 0.66 10.0 4.7 0.18 11.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF4474 PF14751.6 XP_665118.1 - 0.0061 16.0 1.0 0.013 14.9 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4474) Spuma_A9PTase PF03539.14 XP_665118.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Cupin_2 PF07883.11 XP_665119.1 - 0.0041 16.8 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.8 XP_665119.1 - 0.0051 17.0 0.5 0.0089 16.2 0.5 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like DUF4085 PF13315.6 XP_665119.1 - 0.074 12.7 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) GFP PF01353.22 XP_665119.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein DnaJ PF00226.31 XP_665120.1 - 8e-23 80.3 1.3 1.9e-22 79.2 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain VAPB_antitox PF02697.14 XP_665120.1 - 0.068 14.0 7.5 0.77 10.6 0.8 3.0 2 1 1 3 3 3 0 Putative antitoxin HECT PF00632.25 XP_665121.1 - 0.0021 17.6 0.6 0.0025 17.3 0.6 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_hydro_31 PF01055.26 XP_665122.1 - 4.3e-85 286.5 1.3 1.7e-84 284.5 1.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 XP_665122.1 - 2.2e-15 56.7 1.3 8.5e-15 54.8 0.3 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF61 PF01886.16 XP_665122.1 - 0.014 15.4 0.3 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF61 ABC_tran PF00005.27 XP_665123.1 - 2.8e-31 108.8 0.3 5.9e-31 107.8 0.3 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 XP_665123.1 - 6.3e-06 26.2 0.3 0.014 15.2 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 XP_665123.1 - 9.5e-05 21.9 3.6 0.013 14.9 3.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 XP_665123.1 - 0.001 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 XP_665123.1 - 0.002 17.0 5.6 0.0033 16.3 0.9 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 XP_665123.1 - 0.0033 17.7 0.1 0.014 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 XP_665123.1 - 0.0037 17.4 0.3 0.01 15.9 0.3 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 XP_665123.1 - 0.0042 17.6 0.4 0.012 16.1 0.4 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 XP_665123.1 - 0.0053 15.9 0.2 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 XP_665123.1 - 0.0076 16.2 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 XP_665123.1 - 0.0086 16.1 0.1 0.024 14.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 XP_665123.1 - 0.043 14.4 1.0 0.091 13.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 XP_665123.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 XP_665123.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 XP_665123.1 - 0.1 11.8 0.2 0.2 10.8 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 XP_665123.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 XP_665123.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 XP_665123.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 XP_665123.1 - 0.26 11.2 1.0 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 NTPase Brix PF04427.18 XP_665125.1 - 4e-18 66.2 0.1 5.2e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain EF-hand_7 PF13499.6 XP_665126.1 - 1.9e-22 79.5 5.3 2.4e-11 43.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_665126.1 - 6.6e-19 66.0 6.1 4.6e-05 22.7 0.9 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 XP_665126.1 - 4.5e-18 63.6 7.4 1.5e-05 24.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 XP_665126.1 - 1.6e-15 56.6 4.9 6.6e-07 29.1 0.0 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_665126.1 - 2.5e-13 48.9 10.5 3.7e-05 23.0 0.9 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 XP_665126.1 - 1.2e-05 25.5 0.9 0.019 15.3 0.0 3.5 2 2 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 XP_665126.1 - 1.7e-05 24.7 2.5 0.16 12.0 0.3 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 XP_665126.1 - 0.067 13.5 0.1 2.9 8.3 0.0 2.6 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Mcl1_mid PF12341.8 XP_665128.1 - 1.6e-41 142.6 0.0 2.7e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region NPM1-C PF16276.5 XP_665129.1 - 0.02 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain DUF3887 PF13026.6 XP_665129.1 - 0.16 12.8 2.4 21 6.0 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3887) Cyclin_N PF00134.23 XP_665130.1 - 8.5e-12 44.9 0.2 1.4e-11 44.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Imm15 PF15561.6 XP_665132.1 - 0.72 10.1 4.3 42 4.3 4.3 2.2 1 1 0 1 1 1 0 Immunity protein 15 N2227 PF07942.12 XP_665134.1 - 2.1e-94 315.7 0.3 3.4e-94 315.1 0.3 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 XP_665134.1 - 0.00031 21.4 5.4 0.08 13.7 0.0 3.4 2 2 0 2 2 2 2 Methyltransferase domain Thrombin_light PF09396.10 XP_665135.1 - 0.11 12.2 0.6 0.29 10.9 0.6 1.7 1 0 0 1 1 1 0 Thrombin light chain PAP_central PF04928.17 XP_665135.1 - 0.22 10.5 6.2 0.47 9.4 2.8 2.1 1 1 1 2 2 2 0 Poly(A) polymerase central domain Symplekin_C PF12295.8 XP_665136.1 - 5.9e-35 121.1 0.4 1.2e-34 120.1 0.4 1.5 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal tRNA_m1G_MT PF01746.21 XP_665137.1 - 2.5e-14 53.4 0.2 4.2e-14 52.7 0.2 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RRM_1 PF00076.22 XP_665138.1 - 0.0074 16.1 0.0 0.035 13.9 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C78 PF07910.13 XP_665140.1 - 7.8e-30 103.9 0.1 8.8e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase family C78 Sep15_SelM PF08806.11 XP_665140.1 - 0.03 14.5 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Sep15/SelM redox domain Shugoshin_C PF07557.11 XP_665141.1 - 0.0014 18.4 0.6 0.0024 17.6 0.6 1.4 1 0 0 1 1 1 1 Shugoshin C terminus Ribosomal_L19 PF01245.20 XP_665141.1 - 0.0045 16.9 0.2 0.0077 16.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 EMP70 PF02990.16 XP_665141.1 - 0.25 10.0 0.9 0.26 9.9 0.9 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 PH_12 PF16457.5 XP_665141.1 - 1.7 9.2 6.1 0.85 10.1 2.5 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain DUF5401 PF17380.2 XP_665142.1 - 0.18 9.9 15.6 0.21 9.6 15.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Caldesmon PF02029.15 XP_665142.1 - 0.18 10.5 19.1 0.2 10.4 19.1 1.1 1 0 0 1 1 1 0 Caldesmon EssA PF10661.9 XP_665142.1 - 0.37 10.6 12.3 0.49 10.2 12.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA CENP-H PF05837.12 XP_665142.1 - 0.82 10.1 10.3 1.2 9.5 10.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Macoilin PF09726.9 XP_665142.1 - 1.7 7.1 15.0 2.1 6.8 15.0 1.1 1 0 0 1 1 1 0 Macoilin family Radial_spoke_3 PF06098.11 XP_665142.1 - 3.8 6.7 17.6 4.8 6.4 17.6 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Mitofilin PF09731.9 XP_665142.1 - 5.5 5.7 20.5 7.3 5.3 20.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF678 PF05077.12 XP_665144.1 - 0.0062 16.6 2.9 0.99 9.6 0.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF678) zf-C3HC4_2 PF13923.6 XP_665144.1 - 0.078 12.8 0.3 0.078 12.8 0.3 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665144.1 - 0.96 9.5 11.0 0.43 10.6 7.3 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_1 PF14446.6 XP_665144.1 - 1.4 8.9 10.8 0.16 12.0 2.1 2.9 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 DUF2197 PF09963.9 XP_665144.1 - 1.4 9.2 6.2 10 6.5 1.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-RING_11 PF17123.5 XP_665144.1 - 1.6 8.6 9.2 0.15 11.8 3.3 2.4 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 XP_665144.1 - 5.2 7.4 9.0 1.4 9.2 3.5 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF1125 PF06563.11 XP_665145.1 - 0.073 13.0 0.4 0.073 13.0 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1125) PH PF00169.29 XP_665145.1 - 0.31 11.6 8.4 0.038 14.5 3.1 2.3 2 2 0 2 2 2 0 PH domain LRR_6 PF13516.6 XP_665146.1 - 0.014 15.4 0.6 0.018 15.0 0.6 1.2 1 0 0 1 1 1 0 Leucine Rich repeat zf-DNL PF05180.12 XP_665147.1 - 2.1e-21 75.6 4.5 2.1e-21 75.6 4.5 1.6 2 0 0 2 2 2 1 DNL zinc finger DUF3496 PF12001.8 XP_665150.1 - 0.17 12.3 2.6 0.38 11.1 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Macoilin PF09726.9 XP_665150.1 - 1.9 6.9 6.2 2.9 6.3 6.2 1.2 1 0 0 1 1 1 0 Macoilin family ProRS-C_1 PF09180.11 XP_665152.1 - 6.7e-27 93.5 1.3 9.4e-27 93.0 1.3 1.2 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal Pih1_fungal_CS PF18482.1 XP_665152.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal Pih1 CS domain DNA_pol_B PF00136.21 XP_665153.1 - 2.2e-104 349.7 0.2 2.6e-104 349.5 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 XP_665153.1 - 6e-16 58.7 12.0 1.1e-15 57.8 12.0 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.11 XP_665153.1 - 0.84 10.0 13.4 0.99 9.8 1.1 2.7 3 0 0 3 3 3 0 RING-like domain Peptidase_M14 PF00246.24 XP_665155.1 - 4.9e-47 161.1 0.0 6.9e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Pyrophosphatase PF00719.19 XP_665157.1 - 4.1e-44 150.2 0.0 5.2e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF155 PF02582.14 XP_665158.1 - 2.1e-49 168.0 0.1 3.4e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Thioredoxin PF00085.20 XP_665159.1 - 9.9e-21 73.7 0.0 1.3e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 XP_665159.1 - 0.0049 17.0 0.1 0.0076 16.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 XP_665159.1 - 0.012 16.0 0.3 0.084 13.3 0.3 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_6 PF13848.6 XP_665159.1 - 0.025 14.5 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4921 PF16268.5 XP_665159.1 - 0.045 12.6 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) OST3_OST6 PF04756.13 XP_665159.1 - 0.066 12.6 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family zf-MYND PF01753.18 XP_665160.1 - 1.4e-11 44.3 15.2 2.3e-11 43.6 15.2 1.4 1 0 0 1 1 1 1 MYND finger Zn_ribbon_17 PF17120.5 XP_665160.1 - 0.16 11.6 9.9 0.52 10.0 7.8 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C6H2 PF15801.5 XP_665160.1 - 0.59 10.5 15.7 0.1 12.9 12.0 1.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF4363 PF14276.6 XP_665161.1 - 0.056 13.6 1.6 11 6.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Zip PF02535.22 XP_665164.1 - 2.3e-20 73.1 22.8 2.3e-20 73.1 22.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter SLC12 PF03522.15 XP_665164.1 - 0.36 9.8 9.3 0.51 9.3 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Menin PF05053.13 XP_665164.1 - 2.5 6.4 8.6 3.4 5.9 8.6 1.2 1 0 0 1 1 1 0 Menin HATPase_c PF02518.26 XP_665166.1 - 2.5e-22 79.5 0.2 4.7e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 XP_665166.1 - 9.2e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 XP_665166.1 - 0.0036 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold COMM_domain PF07258.14 XP_665167.1 - 0.016 15.3 1.0 0.019 15.1 1.0 1.2 1 0 0 1 1 1 0 COMM domain TRH PF05438.12 XP_665167.1 - 0.064 13.0 0.9 0.065 13.0 0.9 1.0 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Ribosomal_S24e PF01282.19 XP_665168.1 - 2e-28 98.1 0.0 3.3e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Mitofilin PF09731.9 XP_665169.1 - 0.17 10.7 14.1 0.19 10.5 14.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DOR PF14839.6 XP_665169.1 - 1.7 8.5 9.6 2.2 8.2 9.6 1.2 1 0 0 1 1 1 0 DOR family SOBP PF15279.6 XP_665169.1 - 4.5 7.8 7.0 5.2 7.6 7.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein BLM10_N PF16547.5 XP_665169.1 - 5.7 7.3 7.7 0.43 10.9 0.3 2.6 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, N-terminal RPN13_C PF16550.5 XP_665170.1 - 1.2e-21 77.0 0.4 1.8e-21 76.4 0.4 1.3 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 XP_665170.1 - 2.4e-11 44.0 0.3 3.9e-11 43.3 0.3 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2853 PF11015.8 XP_665170.1 - 0.017 15.8 0.1 0.1 13.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2853) AKNA PF12443.8 XP_665170.1 - 0.12 13.0 0.5 0.28 11.9 0.5 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor RNase_HII PF01351.18 XP_665170.1 - 1.5 8.6 4.7 1.8 8.3 4.0 1.5 1 1 0 1 1 1 0 Ribonuclease HII GDPD PF03009.17 XP_665171.1 - 7e-19 68.6 0.1 1.9e-10 40.9 0.2 2.3 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 XP_665171.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF2423 PF10338.9 XP_665174.1 - 9.6e-06 25.7 2.9 9.6e-06 25.7 2.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Adap_comp_sub PF00928.21 XP_665175.1 - 9.5e-56 189.1 4.3 1.2e-55 188.8 4.3 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Herpes_UL92 PF03048.14 XP_665176.1 - 0.004 17.0 1.8 0.0048 16.7 1.8 1.1 1 0 0 1 1 1 1 UL92 family TMPIT PF07851.13 XP_665176.1 - 0.057 12.7 0.7 0.067 12.4 0.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Snf7 PF03357.21 XP_665177.1 - 4.8e-22 78.4 23.1 6.2e-22 78.0 23.1 1.1 1 0 0 1 1 1 1 Snf7 RNase_PH_C PF03725.15 XP_665177.1 - 0.17 12.0 1.9 0.83 9.7 0.2 2.5 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 CpxA_peri PF16527.5 XP_665177.1 - 0.98 9.8 10.0 2.2 8.7 2.3 2.3 2 1 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain CDC50 PF03381.15 XP_665180.1 - 1.1e-54 185.8 0.9 1.1e-54 185.8 0.9 2.3 1 1 2 3 3 3 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TRIQK PF15168.6 XP_665180.1 - 7.6 6.5 7.0 43 4.1 1.9 2.8 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family NGP1NT PF08153.12 XP_665181.1 - 6.7e-34 116.8 0.4 1.3e-33 115.9 0.4 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 XP_665181.1 - 3.4e-17 62.6 0.0 5.9e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 XP_665181.1 - 5.9e-07 29.5 0.0 1.5e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 XP_665181.1 - 2.1e-06 27.3 0.0 2.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 XP_665181.1 - 0.0001 21.8 0.1 0.25 10.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 XP_665181.1 - 0.015 15.4 4.8 1.2 9.2 0.1 3.4 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 XP_665181.1 - 0.023 14.9 0.1 9.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 XP_665182.1 - 2.5e-18 67.1 2.4 8.9e-18 65.2 2.4 1.9 1 1 0 1 1 1 1 SET domain DUF4176 PF13780.6 XP_665182.1 - 0.062 13.4 0.1 0.34 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Nudc_N PF14050.6 XP_665183.1 - 0.057 13.4 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. AMP-binding PF00501.28 XP_665185.1 - 5e-75 252.7 0.0 6.3e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C2 PF00168.30 XP_665186.1 - 0.00064 20.0 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain Ferlin_C PF16165.5 XP_665186.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Ferlin C-terminus GT-D PF08759.11 XP_665187.1 - 0.27 10.9 3.8 0.85 9.2 2.9 1.9 1 1 1 2 2 2 0 Glycosyltransferase GT-D fold Peptidase_C48 PF02902.19 XP_665190.1 - 9.2e-15 55.1 10.9 1.7e-14 54.2 7.4 2.7 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain KH_6 PF15985.5 XP_665191.1 - 4.8e-10 39.6 0.0 7.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 KH domain RNA_pol_Rpb1_1 PF04997.12 XP_665191.1 - 0.016 14.5 0.2 0.021 14.2 0.2 1.2 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 FmiP_Thoc5 PF09766.9 XP_665193.1 - 0.0038 16.6 10.4 0.31 10.3 8.0 2.1 1 1 0 2 2 2 2 Fms-interacting protein/Thoc5 Seryl_tRNA_N PF02403.22 XP_665193.1 - 1.1 9.5 5.5 9.5 6.5 1.4 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 XP_665193.1 - 3.1 8.5 7.2 7.9 7.2 3.4 2.6 1 1 0 2 2 2 0 Initiation control protein YabA Adaptin_N PF01602.20 XP_665196.1 - 7.2e-38 130.4 3.7 7.9e-38 130.3 3.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 XP_665196.1 - 3.1e-08 33.8 2.8 4.3e-08 33.4 0.4 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 XP_665196.1 - 2.9e-05 24.0 0.3 0.0051 17.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat RTP1_C1 PF10363.9 XP_665196.1 - 0.00011 22.4 0.6 0.00085 19.5 0.1 2.5 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 XP_665196.1 - 0.0003 21.1 0.0 0.017 15.5 0.0 2.8 3 1 0 3 3 3 1 HEAT repeats RINT1_TIP1 PF04437.13 XP_665196.1 - 0.039 12.8 0.3 0.056 12.3 0.3 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family ADK_lid PF05191.14 XP_665199.1 - 0.0053 16.7 3.9 0.011 15.6 3.9 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid PHD PF00628.29 XP_665199.1 - 0.0069 16.3 6.6 0.013 15.4 6.6 1.5 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.17 XP_665199.1 - 0.028 14.8 0.5 0.091 13.2 0.0 2.0 2 0 0 2 2 2 0 PWWP domain Rad9_Rad53_bind PF08605.10 XP_665199.1 - 0.041 14.1 0.2 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding C1_1 PF00130.22 XP_665199.1 - 0.044 13.7 0.6 0.044 13.7 0.6 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DPBB_1 PF03330.18 XP_665199.1 - 0.13 12.5 0.1 0.64 10.3 0.0 2.2 2 1 0 2 2 2 0 Lytic transglycolase DZR PF12773.7 XP_665199.1 - 0.33 11.0 4.2 3.4 7.8 0.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 XP_665199.1 - 2.6 7.9 5.3 23 4.9 0.5 3.3 2 1 1 3 3 3 0 zinc-ribbon domain DUF724 PF05266.14 XP_665200.1 - 0.045 13.6 23.7 0.086 12.7 23.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GAGA_bind PF06217.12 XP_665200.1 - 0.074 13.3 7.6 0.1 12.9 7.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1682 PF07946.14 XP_665200.1 - 0.13 11.4 20.9 0.21 10.8 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Tim54 PF11711.8 XP_665200.1 - 0.2 10.4 12.7 0.29 9.9 12.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GvpL_GvpF PF06386.11 XP_665200.1 - 0.22 11.4 7.8 0.36 10.7 7.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UPF0242 PF06785.11 XP_665200.1 - 0.25 11.4 29.4 0.49 10.5 29.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PA26 PF04636.13 XP_665200.1 - 0.29 10.0 14.4 0.47 9.3 14.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 XP_665200.1 - 0.42 9.9 8.9 0.68 9.2 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 XP_665200.1 - 0.44 9.7 5.5 0.5 9.5 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SPT16 PF08644.11 XP_665200.1 - 0.59 10.3 14.9 1.3 9.2 14.9 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Neur_chan_memb PF02932.16 XP_665200.1 - 0.95 9.5 8.6 1.8 8.6 8.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.8 XP_665200.1 - 1.2 9.2 10.1 2.1 8.4 10.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region CobT PF06213.12 XP_665200.1 - 1.9 7.8 19.4 2.8 7.3 19.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TERB2 PF15101.6 XP_665200.1 - 2.1 8.4 14.5 5.2 7.1 14.5 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PBP_sp32 PF07222.12 XP_665200.1 - 2.2 7.7 21.7 3.5 7.0 21.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Presenilin PF01080.17 XP_665200.1 - 3 6.5 16.6 5.7 5.6 16.6 1.4 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 XP_665200.1 - 4.3 7.0 13.1 8 6.2 13.1 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.20 XP_665200.1 - 6.4 4.9 5.3 8.6 4.5 5.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 XP_665200.1 - 7.6 5.2 6.9 12 4.5 6.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF3371 PF11851.8 XP_665200.1 - 9.6 7.3 10.4 4.1 8.5 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) NurA PF09376.10 XP_665201.1 - 0.095 12.4 1.1 0.64 9.7 0.9 2.6 1 1 0 1 1 1 0 NurA domain LIP PF03583.14 XP_665202.1 - 0.21 10.8 0.3 0.38 10.0 0.2 1.5 1 1 0 1 1 1 0 Secretory lipase NAP PF00956.18 XP_665203.1 - 1e-60 205.2 11.4 1e-60 205.2 11.4 2.5 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) BUD22 PF09073.10 XP_665203.1 - 0.19 11.0 8.9 0.29 10.4 8.9 1.3 1 0 0 1 1 1 0 BUD22 Phage_Mu_Gam PF07352.12 XP_665203.1 - 0.34 10.8 5.9 0.073 13.0 1.3 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein LAP1C PF05609.12 XP_665203.1 - 0.41 9.7 7.4 0.97 8.4 0.0 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 XP_665203.1 - 2.2 6.3 17.7 3.7 5.5 17.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi BRCT_assoc PF12820.7 XP_665205.1 - 0.098 12.5 1.8 1.8 8.4 0.4 2.3 1 1 0 2 2 2 0 Serine-rich domain associated with BRCT DUF1772 PF08592.11 XP_665206.1 - 0.67 10.3 9.9 1.4 9.2 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) PspB PF06667.12 XP_665206.1 - 2.4 8.3 7.8 0.78 9.8 0.6 2.6 3 0 0 3 3 3 0 Phage shock protein B Frataxin_Cyay PF01491.16 XP_665207.1 - 3.3e-23 81.8 0.2 4.3e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 Frataxin-like domain Adaptin_N PF01602.20 XP_665209.1 - 2.9e-65 220.8 12.6 4.1e-65 220.3 12.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 XP_665209.1 - 1.9e-22 80.0 1.8 1.9e-22 80.0 1.8 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 XP_665209.1 - 0.00027 21.3 0.1 13 6.2 0.0 4.7 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 XP_665209.1 - 0.00038 20.5 1.0 11 6.6 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat Condensin2nSMC PF12422.8 XP_665209.1 - 0.02 15.1 2.2 1.2 9.3 0.0 3.2 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit V-ATPase_H_C PF11698.8 XP_665209.1 - 0.12 12.5 3.0 2.3 8.3 0.0 3.8 4 1 0 4 4 4 0 V-ATPase subunit H FidL_like PF15941.5 XP_665211.1 - 0.032 14.7 0.4 1.3 9.6 0.1 3.5 2 0 0 2 2 2 0 FidL-like putative membrane protein Synaptobrevin PF00957.21 XP_665212.1 - 5e-15 55.1 0.6 7.9e-15 54.4 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 XP_665212.1 - 9.1e-07 28.8 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SbmA_BacA PF05992.12 XP_665214.1 - 6e-51 173.8 14.2 6.7e-51 173.6 14.2 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 XP_665214.1 - 3.3e-09 36.6 10.7 1.7e-08 34.2 10.7 2.2 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 DUF61 PF01886.16 XP_665214.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF61 Bud13 PF09736.9 XP_665215.1 - 2.2e-26 93.0 4.2 3e-26 92.5 4.2 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex T6PP_N PF18572.1 XP_665216.1 - 0.27 11.1 2.2 0.37 10.7 0.7 2.0 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Cpn60_TCP1 PF00118.24 XP_665218.1 - 9.2e-154 512.7 1.7 1e-153 512.5 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EGF_2 PF07974.13 XP_665218.1 - 4.2 7.8 5.7 3.7 8.0 3.2 2.1 2 0 0 2 2 2 0 EGF-like domain Pkinase PF00069.25 XP_665219.1 - 3.8e-53 180.5 0.0 5.9e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665219.1 - 1.8e-18 66.8 0.0 1.4e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 XP_665219.1 - 0.00013 21.4 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 XP_665219.1 - 0.0025 17.4 0.1 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 XP_665219.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 XP_665219.1 - 0.014 15.4 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 XP_665219.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BSD PF03909.17 XP_665220.1 - 1.2e-06 28.4 2.6 5e-05 23.2 0.0 3.7 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 XP_665221.1 - 0.0025 18.1 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Monellin PF09200.10 XP_665222.1 - 0.12 12.3 0.6 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Monellin ECF_trnsprt PF12822.7 XP_665222.1 - 0.19 11.8 0.3 0.41 10.7 0.3 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Sec63 PF02889.16 XP_665223.1 - 2.5e-16 59.6 2.4 6.4e-16 58.3 2.4 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DUF1493 PF07377.12 XP_665223.1 - 0.12 12.8 0.7 0.55 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) TF_Zn_Ribbon PF08271.12 XP_665224.1 - 0.0019 17.7 2.1 0.0032 17.0 1.8 1.8 1 1 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 XP_665224.1 - 0.0082 15.8 1.3 0.036 13.8 1.5 1.8 1 1 1 2 2 2 1 A2L zinc ribbon domain PPDK_N PF01326.19 XP_665224.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.0 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain zf-RRN7 PF11781.8 XP_665224.1 - 0.02 14.5 0.9 0.028 14.1 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Herpes_UL52 PF03121.15 XP_665225.1 - 2.5e-14 53.0 0.4 2.5e-14 53.0 0.4 1.6 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase Imm5 PF14423.6 XP_665226.1 - 0.24 11.6 1.7 2 8.6 0.2 2.6 1 1 2 3 3 3 0 Immunity protein Imm5 Utp13 PF08625.11 XP_665227.1 - 3.7e-21 75.5 5.9 5.7e-21 74.9 5.5 1.5 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain CbiQ PF02361.16 XP_665228.1 - 0.12 11.9 1.7 0.12 12.0 0.6 1.5 2 0 0 2 2 2 0 Cobalt transport protein TPM_phosphatase PF04536.14 XP_665231.1 - 0.023 14.9 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 TPM domain MOLO1 PF17175.4 XP_665231.1 - 0.026 14.6 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 Prefoldin PF02996.17 XP_665232.1 - 1.5e-18 66.9 0.9 1.5e-18 66.9 0.9 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 XP_665232.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.5 3 1 1 4 4 4 0 Prefoldin subunit CK2S PF15011.6 XP_665232.1 - 0.12 12.2 4.3 0.64 9.9 0.1 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate DivIVA PF05103.13 XP_665232.1 - 0.51 10.4 20.5 0.37 10.9 7.8 2.7 3 0 0 3 3 3 0 DivIVA protein FliD_N PF02465.18 XP_665232.1 - 1.1 10.0 6.6 13 6.5 0.0 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ENT PF03735.14 XP_665234.1 - 0.021 14.9 1.4 0.16 12.1 0.4 2.3 2 1 0 2 2 2 0 ENT domain LPD14 PF18827.1 XP_665234.1 - 0.048 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 ELK PF03789.13 XP_665234.1 - 0.11 12.6 1.0 10 6.4 0.1 3.2 3 0 0 3 3 3 0 ELK domain GRDB PF07355.12 XP_665234.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) BolA PF01722.18 XP_665236.1 - 1.5e-12 47.6 0.0 4.1e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF1870 PF08965.10 XP_665236.1 - 0.084 12.9 0.1 0.13 12.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) DUF773 PF05600.12 XP_665237.1 - 2.6e-05 23.2 12.6 0.00067 18.5 4.7 2.1 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 Med4 PF10018.9 XP_665237.1 - 1.7 8.3 5.3 2.7 7.6 4.5 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Peptidase_M16_M PF16187.5 XP_665240.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 DUF1351 PF07083.11 XP_665240.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Bud13 PF09736.9 XP_665241.1 - 0.091 13.2 11.1 0.043 14.2 7.8 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF3539 PF12058.8 XP_665242.1 - 0.049 13.8 0.1 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3539) C2 PF00168.30 XP_665243.1 - 1.6e-06 28.3 0.0 3.4e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 C2 domain Neur_chan_memb PF02932.16 XP_665244.1 - 3.5 7.6 4.6 6.4 6.8 4.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Helicase_C PF00271.31 XP_665245.1 - 3.8e-12 46.5 0.0 1.4e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 XP_665245.1 - 0.0029 16.4 2.5 0.026 13.2 2.5 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Med31 PF05669.12 XP_665245.1 - 0.096 12.7 0.1 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 SOH1 Pho88 PF10032.9 XP_665246.1 - 0.011 14.9 0.2 0.011 14.9 0.2 1.5 2 0 0 2 2 2 0 Phosphate transport (Pho88) DUF3180 PF11377.8 XP_665246.1 - 0.054 13.6 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) FAM176 PF14851.6 XP_665246.1 - 0.06 13.0 0.1 0.06 13.0 0.1 2.0 2 0 0 2 2 2 0 FAM176 family DUF2561 PF10812.8 XP_665246.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) Presenilin PF01080.17 XP_665246.1 - 0.15 10.8 3.6 0.19 10.4 3.6 1.1 1 0 0 1 1 1 0 Presenilin Kei1 PF08552.11 XP_665246.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.8 2 1 1 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Serinc PF03348.15 XP_665246.1 - 0.54 9.1 4.0 0.65 8.9 4.0 1.3 1 1 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 XP_665246.1 - 0.91 8.5 3.3 0.31 10.0 0.9 1.5 1 1 0 2 2 2 0 CLN3 protein DUF4834 PF16118.5 XP_665246.1 - 1.2 10.1 12.5 0.15 13.0 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EOS1 PF12326.8 XP_665246.1 - 1.4 8.8 6.6 0.24 11.3 1.8 1.9 2 0 0 2 2 2 0 N-glycosylation protein Connexin PF00029.19 XP_665246.1 - 1.7 8.4 8.3 0.18 11.6 2.4 1.9 1 1 0 2 2 2 0 Connexin YMF19 PF02326.15 XP_665246.1 - 2.6 8.9 8.2 0.31 11.9 1.7 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 MAP17 PF15807.5 XP_665246.1 - 3.1 8.1 8.7 0.36 11.1 1.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 O-antigen_lig PF13425.6 XP_665246.1 - 3.7 6.2 8.8 0.092 11.5 0.8 1.9 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Mem_trans PF03547.18 XP_665246.1 - 3.8 5.8 4.9 0.85 7.9 1.6 1.5 1 1 0 2 2 2 0 Membrane transport protein SID-1_RNA_chan PF13965.6 XP_665246.1 - 8.3 4.7 8.2 1.1 7.6 3.8 1.6 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1168 PF06658.12 XP_665247.1 - 9.5e-16 57.8 19.6 1.2e-15 57.5 19.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RRM_1 PF00076.22 XP_665248.1 - 9.5e-27 92.6 1.1 2.9e-12 46.2 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_665248.1 - 1.2e-08 34.9 1.0 0.0052 16.9 0.1 3.1 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 XP_665248.1 - 0.002 18.1 0.3 0.94 9.5 0.1 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 XP_665248.1 - 0.03 14.0 0.3 8.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Proteasome PF00227.26 XP_665249.1 - 9.3e-58 194.9 0.0 1.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 XP_665249.1 - 2e-13 49.7 0.2 3.6e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribo_biogen_C PF04034.13 XP_665251.1 - 1.6e-40 137.8 0.1 4.3e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 XP_665251.1 - 1.2e-05 25.1 0.5 2e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.12 XP_665251.1 - 0.00022 20.7 36.2 0.00022 20.7 36.2 2.0 2 0 0 2 2 2 1 SDA1 Presenilin PF01080.17 XP_665251.1 - 0.0015 17.4 23.2 0.0026 16.6 23.2 1.3 1 0 0 1 1 1 1 Presenilin Spore_coat_CotO PF14153.6 XP_665251.1 - 0.0022 17.9 24.3 0.0035 17.3 24.3 1.3 1 0 0 1 1 1 1 Spore coat protein CotO CCSAP PF15748.5 XP_665251.1 - 0.018 15.2 16.7 0.027 14.6 16.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Raftlin PF15250.6 XP_665251.1 - 0.26 10.0 12.9 0.37 9.5 12.9 1.2 1 0 0 1 1 1 0 Raftlin DUF2151 PF10221.9 XP_665251.1 - 1.4 7.4 15.3 2.1 6.9 15.3 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator NPR3 PF03666.13 XP_665251.1 - 7.7 5.2 21.0 14 4.3 21.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4559 PF15112.6 XP_665252.1 - 0.032 13.9 7.4 0.035 13.8 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ABC_tran_CTD PF16326.5 XP_665252.1 - 0.036 14.3 1.9 0.093 13.0 0.1 2.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain GIT_CC PF16559.5 XP_665252.1 - 0.1 12.5 3.0 1.2 9.1 0.1 2.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tup_N PF08581.10 XP_665252.1 - 0.38 11.1 8.3 0.057 13.7 3.3 2.2 2 1 0 3 3 3 0 Tup N-terminal XhlA PF10779.9 XP_665252.1 - 9 6.6 9.8 2.8 8.2 0.6 3.1 2 2 1 3 3 3 0 Haemolysin XhlA RRP36 PF06102.12 XP_665253.1 - 0.15 12.0 13.5 0.19 11.7 13.2 1.3 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 ABC2_membrane_3 PF12698.7 XP_665253.1 - 0.82 8.7 6.9 1.1 8.2 6.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NOD2_WH PF17779.1 XP_665254.1 - 0.15 12.4 2.5 0.38 11.1 0.1 2.5 2 0 0 2 2 2 0 NOD2 winged helix domain DUF4392 PF14336.6 XP_665255.1 - 6.7e-15 55.3 0.0 4e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4392) IF2_N PF04760.15 XP_665255.1 - 0.27 11.1 1.3 34 4.4 0.0 3.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TSC21 PF15217.6 XP_665256.1 - 1.4 8.8 4.2 3.2 7.7 0.6 2.2 2 0 0 2 2 2 0 TSC21 family Nucleoporin_N PF08801.11 XP_665257.1 - 3.1e-08 32.8 6.2 4.8e-08 32.2 6.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like MFS_1 PF07690.16 XP_665259.1 - 4.4e-15 55.5 13.3 5.5e-15 55.1 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 XP_665259.1 - 0.0028 16.6 6.7 0.0036 16.2 6.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF21 PF01595.20 XP_665259.1 - 0.21 11.3 3.1 0.17 11.6 1.8 1.5 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Pkinase PF00069.25 XP_665260.1 - 1e-41 143.0 0.0 1.3e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665260.1 - 3.6e-37 128.1 0.0 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 XP_665260.1 - 0.016 14.1 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain hGDE_central PF14702.6 XP_665261.1 - 5e-37 127.9 0.4 8.9e-37 127.1 0.4 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme AMPK1_CBM PF16561.5 XP_665261.1 - 1.5e-17 63.6 1.8 6.8e-10 39.0 0.2 2.6 1 1 1 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase 7tm_3 PF00003.22 XP_665261.1 - 0.16 11.7 5.6 0.25 11.0 5.6 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DHHC PF01529.20 XP_665261.1 - 0.57 10.3 7.9 1.4 9.0 7.9 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase Comm PF15957.5 XP_665261.1 - 0.94 9.8 4.0 1 9.7 1.8 2.2 2 0 0 2 2 2 0 Commissureless Pkinase PF00069.25 XP_665263.1 - 2.4e-41 141.9 0.0 5.2e-41 140.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665263.1 - 4.1e-20 72.2 0.0 7.1e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase G-patch PF01585.23 XP_665264.1 - 1.8e-14 53.4 3.0 2.5e-14 52.9 3.0 1.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 XP_665264.1 - 1.3e-09 38.0 0.2 2.3e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 G-patch domain Spore_GerAC PF05504.11 XP_665264.1 - 0.0089 16.3 0.2 0.012 15.8 0.2 1.2 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal tRNA-synt_1 PF00133.22 XP_665265.1 - 2.9e-214 712.8 0.7 2.9e-213 709.5 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 XP_665265.1 - 2.2e-14 53.1 2.9 0.00028 19.8 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 XP_665265.1 - 3e-08 33.8 0.1 6.5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 XP_665265.1 - 2.1e-05 24.1 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PEPcase_2 PF14010.6 XP_665265.1 - 0.085 11.3 0.0 1.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase PPDK_N PF01326.19 XP_665266.1 - 0.0025 17.2 0.0 0.0098 15.2 0.0 1.7 1 1 1 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Mad3_BUB1_I PF08311.12 XP_665266.1 - 0.0096 15.9 0.2 2.1 8.3 0.0 2.6 2 0 0 2 2 2 2 Mad3/BUB1 homology region 1 Suf PF05843.14 XP_665268.1 - 6.7e-10 39.4 17.7 0.0003 20.9 0.3 4.2 2 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_5 PF12688.7 XP_665268.1 - 0.00017 21.8 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_14 PF13428.6 XP_665268.1 - 0.00042 20.9 0.0 1.1 10.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RICTOR_M PF14666.6 XP_665268.1 - 0.0018 18.0 0.1 0.4 10.5 0.0 3.2 1 1 2 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain NRDE-2 PF08424.10 XP_665268.1 - 0.0037 16.4 21.2 0.0091 15.2 2.6 3.4 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference Bap31_Bap29_C PF18035.1 XP_665269.1 - 3.3 7.8 10.1 5.4 7.1 0.6 3.3 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain tRNA-synt_1d PF00750.19 XP_665270.1 - 2.6e-112 375.3 1.9 1.8e-111 372.5 1.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 XP_665270.1 - 6.4e-29 100.5 0.1 1.1e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 XP_665270.1 - 0.00024 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ZinT PF09223.11 XP_665270.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment tRNA-synt_1g PF09334.11 XP_665270.1 - 0.095 11.4 0.0 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (M) Clat_adaptor_s PF01217.20 XP_665272.1 - 2.4e-51 173.4 3.0 2.9e-51 173.1 3.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MCM PF00493.23 XP_665278.1 - 2.9e-45 154.1 0.0 4.2e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 XP_665278.1 - 1.2e-37 128.6 0.4 2e-37 127.9 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain COPI_C PF06957.11 XP_665279.1 - 3.4e-61 207.2 0.1 6.9e-61 206.2 0.1 1.6 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 XP_665279.1 - 1.6e-58 198.9 10.4 4.1e-58 197.5 4.2 2.2 2 0 0 2 2 2 2 Coatomer WD associated region TPR_2 PF07719.17 XP_665279.1 - 0.034 14.2 0.0 0.88 9.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2614 PF11023.8 XP_665280.1 - 0.037 14.1 0.9 0.045 13.8 0.9 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rad60-SLD PF11976.8 XP_665282.1 - 2.3e-21 75.4 0.2 3.6e-21 74.8 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 XP_665282.1 - 3.2e-11 42.8 0.0 4.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 XP_665282.1 - 0.045 14.0 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 UBX domain Methyltransf_23 PF13489.6 XP_665283.1 - 4.5e-12 46.1 0.0 6.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_665283.1 - 3.5e-06 27.7 0.0 9.3e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_665283.1 - 4.2e-05 24.2 0.0 0.011 16.5 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 XP_665283.1 - 0.0002 21.2 0.1 0.00054 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_665283.1 - 0.0034 18.0 0.0 0.053 14.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Sec63 PF02889.16 XP_665285.1 - 4.4e-33 114.5 0.1 7.2e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 XP_665285.1 - 8.9e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CH PF00307.31 XP_665286.1 - 1.4e-06 28.4 0.2 1.4e-06 28.4 0.2 3.4 2 1 0 2 2 2 1 Calponin homology (CH) domain Ank_2 PF12796.7 XP_665287.1 - 4.1e-16 59.3 0.2 6.7e-11 42.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_665287.1 - 8.6e-16 58.1 0.5 5.8e-06 26.7 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 XP_665287.1 - 2.9e-13 49.6 1.7 0.0023 18.3 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 XP_665287.1 - 4e-10 39.1 1.2 0.094 13.3 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 XP_665287.1 - 4.2e-07 30.1 3.2 0.0067 16.7 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) RIBIOP_C PF04950.12 XP_665288.1 - 5.3e-91 305.1 0.1 9.9e-91 304.2 0.1 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 XP_665288.1 - 1.6e-16 60.1 0.0 3.8e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RNA_pol_Rpc4 PF05132.14 XP_665289.1 - 0.00035 21.0 0.0 0.0092 16.4 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase III RPC4 Dus PF01207.17 XP_665290.1 - 4e-43 147.7 0.0 1e-21 77.4 0.0 3.2 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 XP_665290.1 - 0.16 12.0 3.1 0.096 12.6 0.6 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RICH PF05062.12 XP_665292.1 - 0.0094 16.3 2.3 0.045 14.1 2.3 2.0 1 1 0 1 1 1 1 RICH domain TetR_C_19 PF17924.1 XP_665292.1 - 1.2 9.8 7.7 0.42 11.2 4.6 1.7 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PMC2NT PF08066.12 XP_665293.1 - 0.014 16.0 0.1 0.51 11.1 0.1 2.8 2 0 0 2 2 2 0 PMC2NT (NUC016) domain THOC7 PF05615.13 XP_665293.1 - 0.062 13.6 0.4 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Baculo_VP39 PF04501.12 XP_665294.1 - 0.025 14.1 5.2 0.052 13.1 5.2 1.5 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 DUF749 PF05370.11 XP_665294.1 - 0.73 10.0 6.2 0.36 10.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF749) Peptidase_M16_C PF05193.21 XP_665295.1 - 9.9e-09 35.5 4.2 2e-06 28.0 0.3 3.2 3 0 0 3 3 3 3 Peptidase M16 inactive domain Imm6 PF14434.6 XP_665296.1 - 0.00047 20.1 1.5 0.00047 20.1 1.5 2.8 2 1 0 2 2 2 1 Immunity protein Imm6 QIL1 PF15884.5 XP_665296.1 - 9.5 6.9 11.4 33 5.2 4.4 4.0 3 1 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 Ctr PF04145.15 XP_665297.1 - 4.3e-18 66.4 20.1 1.4e-09 38.7 1.5 2.1 1 1 1 2 2 2 2 Ctr copper transporter family H_PPase PF03030.16 XP_665297.1 - 0.0023 16.6 3.8 0.0027 16.4 3.8 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Bac_GDH PF05088.12 XP_665297.1 - 0.12 9.8 0.1 0.14 9.6 0.1 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase HXXEE PF13787.6 XP_665297.1 - 2.9 8.8 9.3 5.8 7.8 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif EzrA PF06160.12 XP_665299.1 - 0.0019 16.5 3.9 0.0034 15.6 3.9 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA zf-CpG_bind_C PF12269.8 XP_665299.1 - 0.013 15.3 0.6 0.027 14.3 0.6 1.5 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain CCDC-167 PF15188.6 XP_665299.1 - 0.022 15.1 1.2 0.066 13.6 1.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 V-ATPase_C PF03223.15 XP_665299.1 - 0.062 12.7 0.4 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 V-ATPase subunit C Fzo_mitofusin PF04799.13 XP_665299.1 - 0.12 11.9 2.6 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 fzo-like conserved region ERM PF00769.19 XP_665299.1 - 0.13 12.1 2.7 0.13 12.1 0.6 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF5094 PF17015.5 XP_665299.1 - 8 6.5 11.6 0.77 9.8 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Ctf8 PF09696.10 XP_665300.1 - 0.012 15.9 0.1 0.019 15.3 0.1 1.3 1 1 0 1 1 1 0 Ctf8 Peptidase_S9 PF00326.21 XP_665301.1 - 6.8e-08 32.2 0.1 3.6e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 XP_665301.1 - 7e-05 22.2 0.0 0.0026 17.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 XP_665301.1 - 0.00035 20.4 0.1 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 XP_665301.1 - 0.0015 18.2 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 XP_665301.1 - 0.0065 16.2 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1749 PF08538.10 XP_665301.1 - 0.0076 15.4 0.1 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) BAAT_C PF08840.11 XP_665301.1 - 0.016 15.1 0.1 0.19 11.6 0.1 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 XP_665301.1 - 0.21 10.9 0.2 0.34 10.2 0.1 1.4 2 0 0 2 2 2 0 Secretory lipase zf-C3HC4 PF00097.25 XP_665302.1 - 1.2e-08 34.6 3.8 4e-08 33.0 3.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_665302.1 - 2.2e-08 33.8 7.6 2.2e-07 30.6 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665302.1 - 2.1e-07 30.8 9.1 5.2e-07 29.5 3.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 XP_665302.1 - 4.1e-07 29.7 7.4 1.8e-06 27.6 4.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_665302.1 - 1.2e-06 28.4 6.9 2.8e-06 27.2 6.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 XP_665302.1 - 2.4e-06 27.8 10.8 2.8e-05 24.3 10.8 2.4 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 XP_665302.1 - 1.9e-05 24.4 5.8 0.00047 20.0 3.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 XP_665302.1 - 0.00025 20.8 6.5 0.00085 19.1 3.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 XP_665302.1 - 0.00035 20.7 6.9 0.0034 17.5 2.6 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 XP_665302.1 - 0.00042 20.5 7.6 0.00042 20.5 7.6 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 XP_665302.1 - 0.0098 16.0 3.9 0.018 15.2 2.5 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 XP_665302.1 - 0.013 15.6 4.5 0.03 14.4 4.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 XP_665302.1 - 0.037 14.3 0.2 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_6 PF14835.6 XP_665302.1 - 0.22 11.4 3.3 0.19 11.6 1.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein BIV_Env PF05858.12 XP_665302.1 - 0.23 9.6 10.5 0.32 9.1 10.5 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Rad50_zn_hook PF04423.14 XP_665302.1 - 0.68 9.8 0.1 0.68 9.8 0.1 3.1 3 0 0 3 3 2 0 Rad50 zinc hook motif zf-MIZ PF02891.20 XP_665302.1 - 0.75 9.6 6.4 12 5.7 3.9 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF4766 PF15973.5 XP_665302.1 - 1.6 9.3 5.2 0.37 11.4 1.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4766) zf-P11 PF03854.14 XP_665302.1 - 2.1 8.1 7.6 0.28 10.9 2.8 2.0 2 0 0 2 2 2 0 P-11 zinc finger GREB1 PF15782.5 XP_665302.1 - 4.8 4.2 17.0 5.7 3.9 17.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec1 PF00995.23 XP_665303.1 - 6e-25 88.5 0.1 6.7e-25 88.3 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Cpn60_TCP1 PF00118.24 XP_665304.1 - 3.7e-163 543.7 2.0 4.3e-163 543.4 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1444 PF07285.11 XP_665305.1 - 0.22 11.0 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Bromodomain PF00439.25 XP_665306.1 - 2.9e-16 59.3 0.4 5.2e-16 58.5 0.4 1.4 1 0 0 1 1 1 1 Bromodomain Paf1 PF03985.13 XP_665306.1 - 0.0027 16.8 8.1 0.0034 16.4 8.1 1.2 1 0 0 1 1 1 1 Paf1 Rhabdo_ncap PF00945.18 XP_665306.1 - 0.023 13.6 1.1 0.032 13.1 1.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Herpes_UL7 PF01677.16 XP_665306.1 - 0.034 13.9 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like CDC45 PF02724.14 XP_665306.1 - 0.047 12.0 9.4 0.057 11.7 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 XP_665306.1 - 2.4 7.4 15.9 4 6.7 15.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 XP_665306.1 - 3.2 6.8 25.5 4.8 6.2 25.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.8 XP_665306.1 - 6.7 5.8 13.7 0.9 8.6 8.3 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF3341 PF11821.8 XP_665307.1 - 0.038 13.6 8.7 0.14 11.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) DUF3336 PF11815.8 XP_665308.1 - 2.2e-28 98.7 2.3 2.2e-28 98.7 2.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 XP_665308.1 - 6.5e-22 78.7 0.0 1.3e-21 77.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Spem1 PF15670.5 XP_665308.1 - 0.12 11.9 1.2 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 HSCB_C PF07743.13 XP_665309.1 - 1e-09 38.7 0.3 1.9e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 XP_665309.1 - 0.0048 17.0 0.3 0.018 15.1 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 XP_665310.1 - 5.4e-08 32.9 1.8 1.1e-07 32.0 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 XP_665310.1 - 0.00073 19.8 2.3 0.0019 18.5 2.3 1.9 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 XP_665310.1 - 0.0019 18.6 0.3 0.0036 17.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1677 PF07911.13 XP_665310.1 - 0.088 13.2 4.5 0.43 11.0 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1677) RINGv PF12906.7 XP_665311.1 - 3.9e-13 49.3 6.3 8.6e-13 48.2 6.3 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 XP_665311.1 - 7.5e-09 35.8 0.1 2.1e-07 31.2 0.1 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 XP_665311.1 - 1.1e-05 25.6 0.1 0.00027 21.2 0.1 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 XP_665311.1 - 0.058 13.7 9.7 0.36 11.2 10.1 2.2 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 XP_665311.1 - 0.13 12.4 3.4 0.35 11.1 3.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain AAA PF00004.29 XP_665312.1 - 2.9e-35 121.6 0.1 6.6e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 XP_665312.1 - 2.7e-07 30.5 0.0 5.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 XP_665312.1 - 3.4e-05 24.0 0.1 0.00032 20.8 0.0 2.3 1 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 XP_665312.1 - 5.4e-05 23.2 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 XP_665312.1 - 5.8e-05 23.1 0.0 0.00024 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 XP_665312.1 - 0.00044 20.5 2.8 0.073 13.3 0.0 3.9 2 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 XP_665312.1 - 0.0018 18.7 0.0 0.072 13.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 XP_665312.1 - 0.0023 17.1 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 XP_665312.1 - 0.0038 17.8 2.7 0.072 13.6 1.3 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 XP_665312.1 - 0.0055 17.1 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 XP_665312.1 - 0.012 15.7 0.0 0.045 13.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 XP_665312.1 - 0.013 15.4 0.1 0.061 13.2 0.1 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 XP_665312.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 XP_665312.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 XP_665312.1 - 0.039 13.3 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 XP_665312.1 - 0.04 13.8 1.5 5.3 6.9 0.0 2.6 2 1 1 3 3 3 0 NACHT domain AAA_24 PF13479.6 XP_665312.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 XP_665312.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 XP_665312.1 - 0.13 12.0 0.0 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_3 PF01171.20 XP_665313.1 - 2.6e-16 59.9 0.0 3.9e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 XP_665313.1 - 5.6e-08 32.2 2.1 5.6e-08 32.2 2.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon PAPS_reduct PF01507.19 XP_665313.1 - 0.0005 20.1 0.0 0.0032 17.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RecR PF02132.15 XP_665313.1 - 0.73 9.4 6.7 0.61 9.7 3.6 2.3 2 0 0 2 2 2 0 RecR protein ATP-synt_D PF01813.17 XP_665314.1 - 6.9e-50 169.6 0.8 1e-49 169.0 0.8 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Alpha_E2_glycop PF00943.19 XP_665314.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Sde2_N_Ubi PF13019.6 XP_665315.1 - 0.011 15.6 4.1 0.012 15.5 3.6 1.4 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain BORCS6 PF10157.9 XP_665315.1 - 0.026 14.7 0.8 0.052 13.8 0.8 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 FIIND PF13553.6 XP_665316.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Function to find NIF PF03031.18 XP_665317.1 - 2.8e-16 59.7 6.3 4.7e-11 42.7 0.4 3.4 2 2 1 3 3 3 3 NLI interacting factor-like phosphatase PNK3P PF08645.11 XP_665317.1 - 0.00061 19.5 0.1 0.057 13.1 0.1 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase DUF3246 PF11596.8 XP_665318.1 - 0.081 12.3 5.7 0.093 12.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CAF1A PF12253.8 XP_665318.1 - 0.22 11.7 12.3 0.28 11.4 12.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A RXT2_N PF08595.11 XP_665318.1 - 0.49 10.4 6.1 0.51 10.3 6.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 XP_665318.1 - 0.64 9.7 3.5 0.73 9.5 3.5 1.2 1 0 0 1 1 1 0 FAM176 family Dicty_REP PF05086.12 XP_665318.1 - 0.81 7.6 6.6 0.93 7.4 6.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Uso1_p115_C PF04871.13 XP_665318.1 - 1.2 9.5 11.3 1.7 9.1 11.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sporozoite_P67 PF05642.11 XP_665318.1 - 2.6 6.0 5.7 2.8 5.9 5.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 XP_665318.1 - 3.5 7.3 16.9 4.1 7.1 16.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prefoldin PF02996.17 XP_665319.1 - 0.014 15.3 0.6 0.031 14.2 0.6 1.6 1 0 0 1 1 1 0 Prefoldin subunit PspA_IM30 PF04012.12 XP_665319.1 - 0.036 13.6 0.5 0.31 10.6 0.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF2205 PF10224.9 XP_665319.1 - 0.063 13.3 0.6 0.17 11.9 0.6 1.7 1 0 0 1 1 1 0 Short coiled-coil protein DASH_Dad4 PF08650.10 XP_665319.1 - 0.085 12.8 0.9 0.8 9.7 0.9 2.5 1 1 0 1 1 1 0 DASH complex subunit Dad4 AKNA PF12443.8 XP_665319.1 - 0.092 13.4 2.3 0.2 12.3 2.3 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor DivIC PF04977.15 XP_665319.1 - 0.093 12.5 0.5 0.093 12.5 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator FapA PF03961.13 XP_665319.1 - 1.9 7.0 4.0 2.5 6.6 3.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 XP_665320.1 - 1.7e-40 139.1 0.0 5.5e-40 137.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665320.1 - 8.2e-18 64.6 0.0 1.5e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_665320.1 - 2.3e-06 27.2 0.0 1.1e-05 24.9 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 XP_665320.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coatomer_WDAD PF04053.14 XP_665321.1 - 1.4e-40 139.7 0.1 2e-40 139.2 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region TPR_1 PF00515.28 XP_665321.1 - 0.0033 17.2 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_665321.1 - 0.0047 17.0 0.1 0.055 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.20 XP_665321.1 - 0.0089 15.9 0.3 0.23 11.4 0.1 2.4 1 1 1 2 2 2 2 Region in Clathrin and VPS TPR_2 PF07719.17 XP_665321.1 - 0.0093 16.0 0.0 0.048 13.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ATP-synt_ab PF00006.25 XP_665322.1 - 6e-105 349.6 0.0 8.1e-105 349.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 XP_665322.1 - 0.077 12.9 0.1 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension DUF1858 PF08984.11 XP_665322.1 - 0.16 12.2 0.7 16 5.8 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1858) ERCC3_RAD25_C PF16203.5 XP_665323.1 - 3.9e-108 360.3 0.1 6.7e-108 359.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 XP_665323.1 - 7.2e-28 97.3 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_665323.1 - 9e-14 51.8 0.6 3.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 XP_665323.1 - 1.6e-09 38.1 0.6 7.1e-09 36.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 XP_665323.1 - 0.0003 19.6 0.0 0.00049 18.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 XP_665325.1 - 2.5e-09 36.9 13.3 5.8e-09 35.7 13.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665325.1 - 0.039 13.9 13.5 0.11 12.5 13.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 XP_665325.1 - 0.057 13.3 12.2 0.19 11.6 12.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Tyrosinase PF00264.20 XP_665325.1 - 0.51 10.6 4.2 0.52 10.5 0.0 2.6 3 0 0 3 3 3 0 Common central domain of tyrosinase Syntaxin-6_N PF09177.11 XP_665328.1 - 0.0062 17.1 1.2 1.3 9.6 0.0 2.8 3 0 0 3 3 3 2 Syntaxin 6, N-terminal DUF4477 PF14780.6 XP_665328.1 - 0.0085 15.7 9.9 0.045 13.4 0.2 3.8 2 2 3 5 5 5 3 Domain of unknown function (DUF4477) PH PF00169.29 XP_665329.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 PH domain CBM_14 PF01607.24 XP_665330.1 - 1.6e-05 25.0 55.0 0.12 12.6 3.0 12.2 4 4 9 13 13 13 8 Chitin binding Peritrophin-A domain DUF2971 PF11185.8 XP_665330.1 - 0.026 15.7 1.0 15 6.9 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2971) cEGF PF12662.7 XP_665330.1 - 1.3 9.0 19.7 3.9 7.5 0.1 6.7 7 0 0 7 7 7 0 Complement Clr-like EGF-like RRM_1 PF00076.22 XP_665331.1 - 0.14 12.0 0.5 0.36 10.7 0.5 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sacchrp_dh_NADP PF03435.18 XP_665333.1 - 2e-05 24.9 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_1 PF00175.21 XP_665334.1 - 3.3e-11 43.8 0.0 6.2e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 XP_665334.1 - 8.7e-11 41.8 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain V-ATPase_H_C PF11698.8 XP_665335.1 - 1e-39 135.3 2.7 2e-39 134.3 0.6 2.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 XP_665335.1 - 6.8e-34 117.6 0.2 1e-33 117.0 0.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.13 XP_665335.1 - 0.0001 21.9 0.7 0.00068 19.2 0.1 2.3 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 XP_665335.1 - 0.014 15.8 0.3 1.4 9.4 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats Arm PF00514.23 XP_665335.1 - 0.046 13.8 1.2 16 5.8 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat EF1_GNE PF00736.19 XP_665336.1 - 1.2e-24 86.3 1.5 1.7e-24 85.8 1.5 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF3069 PF11269.8 XP_665337.1 - 0.021 15.0 0.2 0.051 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) TFIIS_M PF07500.14 XP_665338.1 - 1.6e-24 86.5 1.9 1.6e-24 86.5 1.9 2.6 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 XP_665338.1 - 1.1e-19 69.9 5.6 2.3e-19 68.9 5.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 XP_665338.1 - 3.3e-09 36.6 1.3 3.3e-09 36.6 1.3 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zinc_ribbon_4 PF13717.6 XP_665338.1 - 0.26 11.2 2.2 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zip PF02535.22 XP_665338.1 - 1.1 8.4 9.0 2.4 7.3 9.0 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter DUF3774 PF12609.8 XP_665338.1 - 2 9.5 5.2 3.9 8.6 0.8 2.8 2 0 0 2 2 2 0 Wound-induced protein EIIBC-GUT_N PF03612.14 XP_665338.1 - 3.9 7.2 9.7 2.7 7.7 0.5 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_B PF00430.18 XP_665338.1 - 6.9 6.8 15.2 0.6 10.2 6.8 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SID-1_RNA_chan PF13965.6 XP_665338.1 - 7.7 4.8 8.9 0.46 8.8 3.8 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 GETHR PF05671.11 XP_665339.1 - 5e-06 25.8 1.3 9.1e-06 24.9 1.3 1.4 1 0 0 1 1 1 1 GETHR pentapeptide repeat (5 copies) HGTP_anticodon PF03129.20 XP_665340.1 - 5.6e-22 77.7 0.0 1.9e-21 76.0 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 XP_665340.1 - 9.3e-10 38.8 0.0 7.1e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3522 PF12036.8 XP_665341.1 - 1.4e-16 61.4 19.7 1.4e-10 41.8 10.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3522) WD40 PF00400.32 XP_665343.1 - 1.3e-12 48.0 0.7 0.0004 21.1 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_4 PF16300.5 XP_665343.1 - 2.5e-11 43.3 0.0 5.8e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Type of WD40 repeat DUF1899 PF08953.11 XP_665343.1 - 9.4e-05 22.2 0.0 0.00033 20.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 XP_665343.1 - 0.00067 19.9 0.1 0.011 16.0 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain NPV_P10 PF05531.12 XP_665343.1 - 0.0012 19.3 2.7 0.0023 18.4 1.2 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 XP_665343.1 - 0.065 13.5 0.2 0.61 10.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Lebercilin PF15619.6 XP_665343.1 - 0.22 11.2 4.1 0.06 13.0 0.7 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 XP_665343.1 - 2.5 8.6 4.7 36 4.9 0.2 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Acetyltransf_1 PF00583.25 XP_665344.1 - 7.7e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 XP_665344.1 - 0.001 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GlutR_N PF05201.15 XP_665345.1 - 0.07 12.9 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain ANAPC4_WD40 PF12894.7 XP_665347.1 - 5.6e-07 29.8 0.1 0.2 12.0 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 XP_665347.1 - 0.016 16.0 0.8 26 5.9 0.0 4.4 5 1 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 XP_665347.1 - 0.035 14.1 0.0 5.9 7.0 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DNA_pol_delta_4 PF04081.13 XP_665348.1 - 2.2e-07 31.3 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Tho1_MOS11_C PF18592.1 XP_665348.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.8 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Kazal_2 PF07648.15 XP_665351.1 - 9.7e-07 28.8 6.6 0.015 15.4 4.3 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 XP_665351.1 - 7.8e-05 22.6 4.8 0.16 12.0 2.7 2.6 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain HECT PF00632.25 XP_665353.1 - 9e-43 146.9 0.0 1.2e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SR-25 PF10500.9 XP_665353.1 - 0.78 9.3 6.6 1.5 8.4 6.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ERCC4 PF02732.15 XP_665354.1 - 1.1e-22 80.9 2.5 3e-22 79.5 0.0 2.7 1 1 1 2 2 2 1 ERCC4 domain HHH_8 PF14716.6 XP_665354.1 - 0.0011 19.3 0.0 0.02 15.2 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HTH_45 PF14947.6 XP_665354.1 - 0.014 15.4 0.8 0.1 12.6 0.8 2.6 1 1 0 1 1 1 0 Winged helix-turn-helix HIN PF02760.15 XP_665354.1 - 0.43 10.3 16.9 0.014 15.1 6.9 2.7 2 1 1 3 3 3 0 HIN-200/IF120x domain Dus PF01207.17 XP_665355.1 - 1.8e-68 230.9 0.0 2.7e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 XP_665355.1 - 2.2e-08 33.9 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 XP_665355.1 - 0.00057 19.3 0.0 0.00083 18.7 0.0 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 XP_665355.1 - 0.0052 15.8 0.1 0.0071 15.4 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 XP_665355.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 XP_665355.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase UFD1 PF03152.14 XP_665356.1 - 1.7e-36 125.3 0.0 1.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Fanconi_A PF03511.14 XP_665356.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein SF1-HH PF16275.5 XP_665357.1 - 1.6e-30 105.8 1.3 3.7e-30 104.6 1.3 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 XP_665357.1 - 6.1e-07 29.2 0.0 1.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 XP_665357.1 - 0.0045 17.0 1.4 0.0045 17.0 1.4 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 XP_665357.1 - 0.012 15.6 5.5 0.62 10.1 0.6 2.4 1 1 1 2 2 2 0 Zinc knuckle RRS1 PF04939.12 XP_665358.1 - 3.8e-42 143.9 2.6 3.8e-42 143.9 2.6 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Sec8_exocyst PF04048.14 XP_665358.1 - 0.066 13.1 3.6 0.079 12.8 2.0 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TMEM132D_C PF15706.5 XP_665359.1 - 0.0036 17.0 4.3 0.0075 16.0 0.0 3.4 3 0 0 3 3 3 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BSMAP PF12280.8 XP_665359.1 - 0.0072 16.6 4.3 0.0072 16.6 4.3 2.1 2 0 0 2 2 2 1 Brain specific membrane anchored protein MLANA PF14991.6 XP_665359.1 - 0.13 12.6 4.8 8 6.8 0.1 3.7 3 1 0 3 3 3 0 Protein melan-A AP2 PF00847.20 XP_665360.1 - 1.2e-10 41.4 6.4 1.4e-10 41.2 0.3 3.3 3 1 0 3 3 3 1 AP2 domain HTH_43 PF09904.9 XP_665360.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix RAB3GAP2_N PF14655.6 XP_665361.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 XP_665361.1 - 0.039 14.8 0.0 0.85 10.6 0.0 2.6 2 1 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665361.1 - 0.049 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain IML1 PF12257.8 XP_665362.1 - 7.3e-17 61.4 7.4 2.5e-16 59.6 7.4 1.8 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 PCI PF01399.27 XP_665364.1 - 2.7e-18 66.4 1.2 6.2e-17 62.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 XP_665364.1 - 6.7e-09 36.0 0.1 2.4e-08 34.3 0.1 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 XP_665364.1 - 0.0081 16.2 0.2 0.1 12.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MNE1 PF13762.6 XP_665364.1 - 0.014 15.3 1.1 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component SWIRM PF04433.17 XP_665364.1 - 0.053 13.9 6.8 2.1 8.7 0.2 3.4 1 1 2 3 3 3 0 SWIRM domain EntA_Immun PF08951.10 XP_665364.1 - 0.57 10.6 4.7 0.55 10.6 0.8 2.6 2 0 0 2 2 2 0 Enterocin A Immunity Pkinase PF00069.25 XP_665365.1 - 4.3e-06 26.3 9.9 0.00011 21.7 2.1 2.9 3 0 0 3 3 3 2 Protein kinase domain Ribosomal_S8e PF01201.22 XP_665366.1 - 2.2e-51 173.6 5.4 9.5e-51 171.6 0.5 2.0 1 1 1 2 2 2 2 Ribosomal protein S8e CLP1_P PF16575.5 XP_665367.1 - 7.9e-21 74.7 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 XP_665367.1 - 0.00089 19.3 0.4 0.0035 17.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 XP_665367.1 - 0.0067 16.8 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 XP_665367.1 - 0.022 15.2 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 XP_665367.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 XP_665367.1 - 0.041 13.8 1.4 0.084 12.8 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 XP_665367.1 - 0.064 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 XP_665367.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 XP_665367.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 XP_665367.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Phage_holin_6_1 PF09682.10 XP_665368.1 - 0.012 16.0 1.0 0.026 14.9 1.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Methyltransf_PK PF05891.12 XP_665369.1 - 1.1e-42 146.0 0.0 1.4e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 XP_665369.1 - 2.7e-07 31.2 0.0 7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_665369.1 - 1.5e-06 28.7 0.0 3.7e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 XP_665369.1 - 0.0093 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 XP_665369.1 - 0.11 13.3 0.0 0.46 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 XP_665369.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 XP_665369.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TP_methylase PF00590.20 XP_665370.1 - 1.6e-22 80.5 0.0 3.5e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF747 PF05346.11 XP_665371.1 - 1.5e-17 64.1 1.0 1.5e-17 64.1 1.0 1.8 2 0 0 2 2 2 1 Eukaryotic membrane protein family GoLoco PF02188.17 XP_665371.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.5 3 0 0 3 3 3 0 GoLoco motif AIM24 PF01987.17 XP_665372.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 S1 PF00575.23 XP_665373.1 - 3e-05 24.3 0.2 0.0071 16.7 0.0 3.8 4 1 0 4 4 4 1 S1 RNA binding domain ProQ_C PF17516.2 XP_665373.1 - 0.019 14.4 0.0 0.087 12.3 0.0 2.0 2 0 0 2 2 2 0 ProQ C-terminal domain RNA_pol_Rbc25 PF08292.12 XP_665373.1 - 0.087 13.1 0.0 59 3.9 0.0 3.6 3 1 0 3 3 3 0 RNA polymerase III subunit Rpc25 zf-CW PF07496.15 XP_665374.1 - 5.3e-16 58.4 5.9 5.3e-16 58.4 5.9 2.0 2 0 0 2 2 2 1 CW-type Zinc Finger L31 PF09784.9 XP_665374.1 - 1.1 9.7 4.8 0.9 10.0 2.2 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 IF-2B PF01008.17 XP_665376.1 - 3.9e-14 52.5 0.0 5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF505 PF04458.12 XP_665376.1 - 0.077 11.4 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DUF2624 PF11116.8 XP_665376.1 - 0.15 13.0 1.3 0.36 11.7 0.1 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2624) Fib_alpha PF08702.10 XP_665377.1 - 0.24 11.6 13.2 0.16 12.2 11.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Keratin_2_head PF16208.5 XP_665379.1 - 0.0033 17.6 14.7 0.006 16.7 14.7 1.5 1 0 0 1 1 1 1 Keratin type II head RIH_assoc PF08454.11 XP_665379.1 - 0.02 14.8 0.1 0.062 13.1 0.1 1.8 1 0 0 1 1 1 0 RyR and IP3R Homology associated Hexapep PF00132.24 XP_665379.1 - 0.067 12.9 15.3 0.26 11.1 5.7 2.6 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) HAD_2 PF13419.6 XP_665379.1 - 1.1 9.4 3.9 13 5.8 0.0 2.6 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.26 XP_665380.1 - 2.3e-47 160.9 0.3 2.9e-47 160.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1676 PF07898.13 XP_665381.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) NHase_alpha PF02979.16 XP_665381.1 - 0.17 11.1 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Presenilin PF01080.17 XP_665382.1 - 0.61 8.8 2.7 0.65 8.7 2.7 1.1 1 0 0 1 1 1 0 Presenilin zf-A20 PF01754.16 XP_665383.1 - 0.0093 15.9 0.8 3.7 7.6 0.1 2.7 2 0 0 2 2 2 2 A20-like zinc finger Peroxin-22 PF12827.7 XP_665385.1 - 0.84 9.6 7.4 0.28 11.1 2.7 2.6 2 1 0 2 2 2 0 Peroxisomal biogenesis protein family Ins_P5_2-kin PF06090.12 XP_665386.1 - 0.15 11.5 12.9 0.52 9.7 13.0 1.7 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Cnd1 PF12717.7 XP_665386.1 - 8.3 6.4 9.7 5.3 7.1 1.0 2.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cep57_CLD_2 PF14197.6 XP_665387.1 - 0.045 13.8 2.6 0.25 11.4 2.6 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4834 PF16118.5 XP_665388.1 - 0.015 16.2 0.3 0.015 16.2 0.3 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) DUF4692 PF15763.5 XP_665388.1 - 0.082 13.4 0.0 0.082 13.4 0.0 2.2 2 1 1 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) OAD_gamma PF04277.13 XP_665388.1 - 0.28 11.8 0.0 0.28 11.8 0.0 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain ATP-synt_B PF00430.18 XP_665388.1 - 0.51 10.4 1.8 2 8.5 1.8 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) CRCB PF02537.15 XP_665388.1 - 2 8.8 8.5 3.5 8.0 7.0 2.2 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Tetraspanin PF00335.20 XP_665388.1 - 5.4 6.7 23.4 13 5.4 18.6 2.5 1 1 0 1 1 1 0 Tetraspanin family PIG-P PF08510.12 XP_665388.1 - 8.3 6.4 15.7 0.037 14.0 4.2 2.2 1 1 1 2 2 2 0 PIG-P TSP_1 PF00090.19 XP_665389.1 - 0.12 12.7 0.2 0.12 12.7 0.2 4.9 4 1 2 6 6 6 0 Thrombospondin type 1 domain DUF3656 PF12392.8 XP_665391.1 - 0.026 15.2 1.0 0.043 14.5 1.0 1.3 1 0 0 1 1 1 0 Collagenase DAD PF02109.16 XP_665392.1 - 1.1e-25 90.1 4.2 1.4e-25 89.7 4.2 1.1 1 0 0 1 1 1 1 DAD family DUF4022 PF13214.6 XP_665393.1 - 0.045 14.0 1.9 0.14 12.5 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) Pkinase PF00069.25 XP_665394.1 - 8.8e-30 103.9 0.4 1.6e-29 103.1 0.4 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665394.1 - 7.5e-12 45.1 0.1 1.5e-11 44.1 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 XP_665394.1 - 5e-05 22.8 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 XP_665394.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cullin PF00888.22 XP_665395.1 - 1e-06 27.7 0.7 1.5e-06 27.1 0.1 1.5 2 0 0 2 2 2 1 Cullin family Acetyltransf_1 PF00583.25 XP_665396.1 - 2.8e-08 34.0 0.0 3.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 XP_665396.1 - 2.1e-07 31.3 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 XP_665396.1 - 4.4e-05 23.4 0.1 5.9e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 XP_665396.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 XP_665396.1 - 0.0051 16.9 0.1 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Kri1_C PF12936.7 XP_665399.1 - 1.1e-24 86.4 1.9 1.1e-24 86.4 1.9 6.1 6 1 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 XP_665399.1 - 4.9e-15 56.0 17.1 4.9e-15 56.0 17.1 5.0 4 2 1 5 5 5 1 KRI1-like family FYVE PF01363.21 XP_665399.1 - 0.026 14.7 2.8 0.066 13.4 2.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger ZZ PF00569.17 XP_665399.1 - 0.061 13.1 9.7 0.18 11.6 9.5 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type PH PF00169.29 XP_665400.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 PH domain V-SNARE_C PF12352.8 XP_665401.1 - 1.7e-06 28.2 2.5 4.5e-06 26.9 2.5 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 XP_665401.1 - 0.022 14.7 2.7 0.022 14.7 2.7 2.7 3 1 0 3 3 3 0 Sec20 DHO_dh PF01180.21 XP_665401.1 - 0.23 10.6 1.5 0.32 10.2 1.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Lipase_GDSL_3 PF14606.6 XP_665401.1 - 1.9 8.6 5.8 0.68 10.0 2.5 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Microtub_bind PF13931.6 XP_665401.1 - 3.8 7.9 12.1 3.4 8.0 0.4 2.4 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding RabGAP-TBC PF00566.18 XP_665402.1 - 1.3e-29 103.4 9.7 1.3e-29 103.4 9.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Phage_pRha PF09669.10 XP_665402.1 - 0.057 14.0 2.6 0.89 10.2 0.0 2.7 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) COXG PF06240.13 XP_665404.1 - 0.021 14.5 0.6 0.029 14.1 0.6 1.2 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) DUP PF00674.18 XP_665404.1 - 0.024 14.8 2.6 0.044 13.9 0.4 2.0 2 0 0 2 2 2 0 DUP family DUF4834 PF16118.5 XP_665404.1 - 0.92 10.5 6.9 15 6.6 6.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DHHC PF01529.20 XP_665405.1 - 1.7e-34 118.8 17.7 1.7e-34 118.8 17.7 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase CTV_P6 PF06706.11 XP_665405.1 - 0.034 13.9 0.7 0.034 13.9 0.7 2.8 2 1 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Ribosomal_L37e PF01907.19 XP_665406.1 - 5.7e-25 87.2 13.9 5.7e-25 87.2 13.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e SelR PF01641.18 XP_665406.1 - 0.0079 16.3 0.3 0.0083 16.2 0.3 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 XP_665406.1 - 0.01 15.8 1.2 0.014 15.4 1.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 XP_665406.1 - 0.043 13.8 1.3 0.062 13.3 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-P11 PF03854.14 XP_665406.1 - 0.047 13.4 0.7 0.066 12.9 0.7 1.2 1 0 0 1 1 1 0 P-11 zinc finger Rubredoxin_2 PF18073.1 XP_665406.1 - 0.15 11.9 3.0 3.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain PCI PF01399.27 XP_665407.1 - 5.3e-06 26.9 0.8 8.9e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 PCI domain TIMELESS_C PF05029.13 XP_665408.1 - 1.7e-06 27.5 24.3 3.8e-06 26.3 10.3 4.0 3 1 0 3 3 3 1 Timeless protein C terminal region Myb_DNA-bind_6 PF13921.6 XP_665408.1 - 0.0004 20.6 1.3 0.0018 18.5 1.3 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 XP_665408.1 - 0.0064 16.7 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_33 PF13592.6 XP_665408.1 - 0.2 11.3 0.1 0.62 9.7 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix FAM176 PF14851.6 XP_665408.1 - 0.26 10.9 14.6 2.5 7.8 4.7 3.6 3 0 0 3 3 3 0 FAM176 family DUF4611 PF15387.6 XP_665408.1 - 2.1 8.6 18.9 1.8 8.8 0.7 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) WD40 PF00400.32 XP_665409.1 - 0.00017 22.3 0.9 0.32 12.0 0.2 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat PsbQ PF05757.11 XP_665409.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ANAPC4_WD40 PF12894.7 XP_665409.1 - 0.1 12.9 0.1 5.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF502 PF04367.13 XP_665410.1 - 0.072 13.0 1.7 0.15 12.0 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF502) DsrC PF04358.13 XP_665410.1 - 0.079 13.5 0.3 0.63 10.6 0.1 2.4 2 0 0 2 2 2 0 DsrC like protein DUF2704 PF10866.8 XP_665410.1 - 0.12 12.2 2.0 0.21 11.5 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2704) TBCC PF07986.12 XP_665412.1 - 4.3e-24 84.5 2.5 6.3e-24 84.0 2.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 XP_665412.1 - 0.47 10.1 5.8 0.47 10.1 1.7 2.1 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) C terminal SET PF00856.28 XP_665414.1 - 2.4e-11 44.3 1.2 2.7e-11 44.1 0.6 1.4 1 1 0 1 1 1 1 SET domain DUF5640 PF18692.1 XP_665414.1 - 0.18 11.9 0.8 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5640) GYF PF02213.16 XP_665415.1 - 4.7e-05 23.0 0.1 0.00017 21.2 0.0 2.0 2 0 0 2 2 2 1 GYF domain BTB PF00651.31 XP_665415.1 - 0.0045 17.2 0.1 0.023 14.9 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain DAOA PF15199.6 XP_665416.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 D-amino acid oxidase activator GYF PF02213.16 XP_665417.1 - 0.038 13.7 0.3 0.038 13.7 0.3 1.9 2 0 0 2 2 2 0 GYF domain GYF_2 PF14237.6 XP_665417.1 - 0.074 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 GYF domain 2 Helicase_C PF00271.31 XP_665417.1 - 0.099 13.0 3.1 0.11 12.8 0.3 2.5 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF1523 PF07509.11 XP_665418.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Asp_decarbox PF02261.16 XP_665418.1 - 0.065 13.2 0.1 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Aspartate decarboxylase Ribosomal_L19e PF01280.20 XP_665419.1 - 2.5e-42 144.4 13.2 3.7e-42 143.8 13.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19e NPCC PF08058.11 XP_665420.1 - 6.5 6.8 8.4 1 9.4 1.8 2.0 2 0 0 2 2 2 0 Nuclear pore complex component DIM1 PF02966.16 XP_665421.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 EF-hand_6 PF13405.6 XP_665421.1 - 0.18 11.8 0.9 2.4 8.3 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain PIG-X PF08320.12 XP_665424.1 - 3.8e-12 46.6 0.1 1.4e-11 44.8 0.1 1.8 1 1 0 1 1 1 1 PIG-X / PBN1 Exo_endo_phos PF03372.23 XP_665425.1 - 3.7e-06 26.6 0.0 1.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fil_haemagg_2 PF13332.6 XP_665425.1 - 0.045 13.9 1.5 0.08 13.1 1.5 1.3 1 0 0 1 1 1 0 Hemagglutinin repeat zf-C3HC4_2 PF13923.6 XP_665427.1 - 3.9e-11 42.6 11.1 7.5e-11 41.7 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665427.1 - 3.7e-09 36.3 11.8 9.4e-09 35.0 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_665427.1 - 8.7e-09 35.1 11.9 1.7e-08 34.2 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_665427.1 - 1.1e-07 31.5 12.0 2.4e-07 30.5 12.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 XP_665427.1 - 7e-07 29.5 12.9 1.5e-06 28.4 12.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 XP_665427.1 - 1.5e-06 28.1 8.4 3.3e-06 27.0 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_665427.1 - 1.5e-05 24.9 12.8 3e-05 23.9 12.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 XP_665427.1 - 0.00039 20.7 7.4 0.0014 18.9 7.4 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 XP_665427.1 - 0.003 17.4 6.2 0.0062 16.4 6.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 XP_665427.1 - 0.0042 17.2 9.5 0.011 15.9 9.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4200 PF13863.6 XP_665427.1 - 0.005 17.2 0.8 0.005 17.2 0.8 5.9 4 2 0 4 4 4 1 Domain of unknown function (DUF4200) Prp19 PF08606.11 XP_665427.1 - 0.0075 16.2 3.9 0.17 11.9 0.1 4.0 3 1 0 3 3 3 1 Prp19/Pso4-like TMF_DNA_bd PF12329.8 XP_665427.1 - 0.015 15.3 14.3 0.015 15.3 14.3 7.8 7 1 0 7 7 6 0 TATA element modulatory factor 1 DNA binding zf-UDP PF14569.6 XP_665427.1 - 0.018 15.1 5.2 0.058 13.5 5.2 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 XP_665427.1 - 0.13 12.1 10.0 0.44 10.4 10.0 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 XP_665427.1 - 0.29 11.0 0.0 0.29 11.0 0.0 7.7 9 0 0 9 9 7 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 XP_665427.1 - 0.82 9.8 4.7 1.6 8.8 4.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF745 PF05335.13 XP_665427.1 - 2.5 7.8 10.0 0.87 9.3 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF745) HSBP1 PF06825.12 XP_665427.1 - 4.4 7.2 8.7 19 5.2 0.9 3.9 4 0 0 4 4 3 0 Heat shock factor binding protein 1 TbpB_C PF17483.2 XP_665429.1 - 0.047 14.1 1.8 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B KID PF02524.14 XP_665430.1 - 1.5 9.3 4.4 1.3 9.4 0.1 3.5 3 0 0 3 3 3 0 KID repeat NOT2_3_5 PF04153.18 XP_665431.1 - 5.4e-29 100.9 12.2 7.1e-29 100.5 12.2 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Endotoxin_N PF03945.14 XP_665432.1 - 0.00079 19.2 3.0 0.15 11.7 0.5 2.5 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain DUF386 PF04074.12 XP_665432.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 YhcH/YjgK/YiaL AMP-binding PF00501.28 XP_665433.1 - 4.4e-68 229.8 0.0 6.2e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme XPG_N PF00752.17 XP_665434.1 - 3.5e-27 94.8 0.0 1.2e-26 93.2 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 XP_665434.1 - 9.8e-23 80.3 0.0 9.8e-23 80.3 0.0 3.5 3 1 1 4 4 4 1 XPG I-region 5_3_exonuc PF01367.20 XP_665434.1 - 0.17 12.5 0.0 0.17 12.5 0.0 4.2 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Trypan_PARP PF05887.11 XP_665434.1 - 0.73 9.8 57.4 0.045 13.7 24.4 3.4 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) DUF3641 PF12345.8 XP_665434.1 - 4.7 7.2 7.6 4.3 7.4 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3641) DUF3437 PF11919.8 XP_665435.1 - 1.6e-25 88.9 0.0 2.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Peptidase_M16 PF00675.20 XP_665436.1 - 4.2e-10 39.8 0.1 7.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WD40 PF00400.32 XP_665438.1 - 2.4e-06 28.2 0.1 0.027 15.4 0.0 4.1 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665438.1 - 2.7e-05 24.4 0.0 1.7 9.0 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 XP_665438.1 - 0.0027 17.0 1.4 1.5 8.0 0.0 2.3 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 XP_665438.1 - 0.0044 16.0 0.1 0.013 14.5 0.1 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 XP_665438.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.5 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 XP_665438.1 - 0.062 12.9 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain zf-CCCH_4 PF18044.1 XP_665440.1 - 3.4e-07 29.9 3.5 8.2e-07 28.7 3.5 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 XP_665440.1 - 2.6e-06 27.3 7.7 5.8e-06 26.2 7.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 XP_665440.1 - 3.3e-06 26.8 1.3 6.8e-06 25.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 XP_665440.1 - 0.0023 18.6 0.7 0.0059 17.3 0.7 1.6 1 0 0 1 1 1 1 Torus domain PQQ_3 PF13570.6 XP_665440.1 - 0.16 12.5 0.0 2.2 8.9 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain zf-CCCH_2 PF14608.6 XP_665440.1 - 0.31 11.6 4.4 0.94 10.0 4.4 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TRAPPC10 PF12584.8 XP_665441.1 - 0.00012 21.9 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 XP_665441.1 - 0.0026 17.7 0.0 0.008 16.2 0.0 1.9 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking PRP21_like_P PF12230.8 XP_665441.1 - 0.092 12.6 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein CppA_N PF14506.6 XP_665443.1 - 0.018 15.1 2.3 0.032 14.3 1.9 1.6 1 1 0 1 1 1 0 CppA N-terminal DUF3450 PF11932.8 XP_665443.1 - 0.021 14.2 5.4 0.028 13.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 XP_665443.1 - 3.6 8.1 13.1 10 6.7 13.1 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Gpi16 PF04113.14 XP_665444.1 - 2.9e-11 42.5 0.0 3.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component MIP-T3 PF10243.9 XP_665445.1 - 0.013 15.5 2.6 0.029 14.4 1.9 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain DUF1827 PF08860.10 XP_665445.1 - 0.19 12.0 4.3 0.12 12.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) DUF1279 PF06916.13 XP_665446.1 - 1.3e-22 80.1 1.2 2e-22 79.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Sarcolipin PF05366.11 XP_665446.1 - 0.16 11.7 1.9 0.32 10.7 1.9 1.5 1 0 0 1 1 1 0 Sarcolipin Actin PF00022.19 XP_665447.1 - 6e-22 77.8 0.0 7.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Actin Pkinase PF00069.25 XP_665449.1 - 3.4e-08 33.2 0.1 3.4e-08 33.2 0.1 2.7 4 0 0 4 4 4 1 Protein kinase domain UPF0146 PF03686.13 XP_665450.1 - 0.17 11.8 0.1 0.8 9.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) DUF4834 PF16118.5 XP_665450.1 - 4.8 8.2 8.3 31 5.6 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MAT1 PF06391.13 XP_665451.1 - 1e-09 38.5 15.5 2.8e-09 37.1 15.2 1.8 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 XP_665451.1 - 7.8e-07 29.3 7.1 9.2e-07 29.1 5.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 XP_665451.1 - 4.8e-05 23.1 13.0 0.00079 19.3 12.1 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665451.1 - 0.00021 21.2 8.0 0.00021 21.2 8.0 2.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 XP_665451.1 - 0.00035 20.4 6.5 0.0015 18.3 6.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 XP_665451.1 - 0.00036 20.3 8.8 0.0019 18.0 5.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_665451.1 - 0.00044 20.0 10.5 0.02 14.7 10.5 3.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 XP_665451.1 - 0.00064 19.8 3.1 0.0015 18.6 3.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 XP_665451.1 - 0.00079 19.4 1.7 0.00079 19.4 1.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 XP_665451.1 - 0.0018 18.0 5.6 0.0056 16.5 5.6 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 XP_665451.1 - 0.0027 17.5 11.3 0.46 10.4 8.6 2.8 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 DZR PF12773.7 XP_665451.1 - 0.33 11.0 6.5 1.6 8.8 6.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 XP_665451.1 - 0.35 11.0 13.1 1.2 9.4 5.8 3.5 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Prim_Zn_Ribbon PF08273.12 XP_665451.1 - 0.36 11.1 6.2 0.45 10.8 1.9 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Ribosomal_L37ae PF01780.19 XP_665451.1 - 1.6 8.9 4.7 3.4 7.8 1.4 2.6 2 1 0 2 2 2 0 Ribosomal L37ae protein family Wx5_PLAF3D7 PF09688.10 XP_665451.1 - 2.1 8.4 9.0 1.4 8.9 6.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) zf-rbx1 PF12678.7 XP_665451.1 - 6.8 7.1 9.5 83 3.6 9.4 2.7 1 1 1 2 2 2 0 RING-H2 zinc finger domain Abhydrolase_2 PF02230.16 XP_665452.1 - 3.1e-27 95.8 0.1 4.2e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 XP_665452.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 XP_665452.1 - 0.0027 17.6 0.0 0.0078 16.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF676 PF05057.14 XP_665452.1 - 0.014 14.9 0.1 0.023 14.2 0.1 1.3 1 1 0 1 1 1 0 Putative serine esterase (DUF676) AXE1 PF05448.12 XP_665452.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 XP_665452.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Nrap_D4 PF17405.2 XP_665453.1 - 3.2e-26 92.0 0.1 7.1e-26 90.9 0.1 1.6 1 1 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 XP_665453.1 - 6.2e-19 68.6 0.1 1.6e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 XP_665453.1 - 8.5e-16 58.1 0.1 1.5e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 ER_lumen_recept PF00810.18 XP_665454.1 - 3.9e-49 167.3 14.2 5.7e-49 166.7 14.2 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 XP_665454.1 - 0.028 14.2 1.7 0.028 14.2 1.7 3.8 2 1 2 4 4 4 0 PQ loop repeat Caldesmon PF02029.15 XP_665456.1 - 5.4e-12 45.3 61.4 2.4e-11 43.1 31.8 2.2 2 0 0 2 2 2 2 Caldesmon Presenilin PF01080.17 XP_665456.1 - 3.8e-07 29.2 31.0 1.1e-06 27.7 15.9 2.6 2 0 0 2 2 2 2 Presenilin DDHD PF02862.17 XP_665456.1 - 3.1e-06 27.5 17.2 0.0075 16.5 0.0 3.6 2 1 1 3 3 3 2 DDHD domain Na_trans_assoc PF06512.13 XP_665456.1 - 1.7e-05 25.2 10.3 1.7e-05 25.2 10.3 3.9 3 2 1 4 4 3 1 Sodium ion transport-associated Hid1 PF12722.7 XP_665456.1 - 0.0001 20.6 19.6 0.0001 20.6 19.6 2.7 2 0 0 2 2 2 1 High-temperature-induced dauer-formation protein SDA1 PF05285.12 XP_665456.1 - 0.00041 19.9 99.1 0.051 13.0 22.9 2.3 2 0 0 2 2 2 2 SDA1 CDC45 PF02724.14 XP_665456.1 - 0.0011 17.4 10.5 0.0011 17.4 10.5 3.1 2 1 0 2 2 1 1 CDC45-like protein Paf1 PF03985.13 XP_665456.1 - 0.004 16.2 25.3 0.004 16.2 25.3 3.9 3 2 2 5 5 3 1 Paf1 Neur_chan_memb PF02932.16 XP_665456.1 - 0.0089 16.1 4.3 0.0089 16.1 4.3 3.0 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region LAP1C PF05609.12 XP_665456.1 - 0.92 8.5 40.4 1 8.4 5.6 2.6 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 XP_665456.1 - 1.9 7.7 93.3 0.026 13.9 17.8 2.6 3 0 0 3 3 3 0 BUD22 NUFIP1 PF10453.9 XP_665460.1 - 0.0051 16.6 0.9 0.029 14.2 0.9 2.5 1 1 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 XP_665460.1 - 0.046 14.0 1.3 0.046 14.0 1.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CTP_transf_like PF01467.26 XP_665462.1 - 6.4e-24 84.8 0.3 1.2e-23 83.9 0.3 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like MTS PF05175.14 XP_665463.1 - 5.2e-08 32.6 0.0 8.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 XP_665463.1 - 0.00027 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 XP_665463.1 - 0.00053 19.8 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain rRNA_methylase PF06962.12 XP_665463.1 - 0.0043 17.0 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_18 PF12847.7 XP_665463.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 XP_665463.1 - 0.019 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 XP_665463.1 - 0.023 15.4 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 XP_665463.1 - 0.043 14.8 0.0 0.084 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.14 XP_665463.1 - 0.045 13.3 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 UPF0020 PF01170.18 XP_665463.1 - 0.061 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PRMT5 PF05185.16 XP_665463.1 - 0.079 12.8 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 XP_665463.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_33 PF10017.9 XP_665463.1 - 0.21 10.7 0.0 0.58 9.3 0.0 1.6 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent BCNT PF07572.12 XP_665464.1 - 4.3e-17 61.9 2.6 4.3e-17 61.9 2.6 1.5 2 0 0 2 2 2 1 Bucentaur or craniofacial development PRP38_assoc PF12871.7 XP_665465.1 - 0.0039 17.8 42.0 0.0039 17.8 42.0 4.5 4 1 0 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Amelogenin PF02948.15 XP_665465.1 - 0.15 12.7 14.0 0.31 11.7 14.0 1.4 1 0 0 1 1 1 0 Amelogenin Ion_trans PF00520.31 XP_665465.1 - 1.6 7.9 6.9 0.7 9.1 3.2 2.2 2 0 0 2 2 2 0 Ion transport protein cEGF PF12662.7 XP_665466.1 - 5e-05 23.1 5.4 5e-05 23.1 5.4 2.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.7 XP_665466.1 - 7.2e-05 22.9 7.8 7.2e-05 22.9 7.8 2.8 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.15 XP_665466.1 - 0.0012 19.0 10.5 0.0012 19.0 10.5 3.0 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF PF00008.27 XP_665466.1 - 0.023 15.0 3.4 0.023 15.0 3.4 2.9 2 1 0 2 2 2 0 EGF-like domain Sec20 PF03908.13 XP_665468.1 - 5.6e-06 26.2 1.5 1e-05 25.3 1.5 1.5 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 XP_665468.1 - 5e-05 23.5 0.7 7.8e-05 22.9 0.7 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus RRP36 PF06102.12 XP_665469.1 - 7.6e-30 104.1 21.5 7.6e-30 104.1 21.5 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Neuromodulin_N PF10580.9 XP_665469.1 - 0.019 14.8 1.0 0.075 12.9 1.0 2.1 1 0 0 1 1 1 0 Gap junction protein N-terminal region CPSF_A PF03178.15 XP_665470.1 - 4.5e-18 65.6 0.1 2.2e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 CPSF A subunit region Ac76 PF05814.11 XP_665471.1 - 0.079 13.0 1.9 0.13 12.3 0.4 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) Seipin PF06775.14 XP_665473.1 - 2.3e-26 93.1 14.1 3.4e-25 89.3 14.1 2.4 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Pathogen_betaC1 PF09593.10 XP_665473.1 - 0.16 11.9 0.7 15 5.6 0.0 3.1 3 0 0 3 3 3 0 Beta-satellite pathogenicity beta C1 protein KASH PF10541.9 XP_665473.1 - 3.5 8.0 5.4 14 6.0 1.4 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain RRM_1 PF00076.22 XP_665474.1 - 1e-16 60.5 0.0 1.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 XP_665474.1 - 0.00025 21.0 0.0 0.00078 19.4 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 XP_665474.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif CDC45 PF02724.14 XP_665474.1 - 1.4 7.2 3.3 1.5 7.0 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CBFD_NFYB_HMF PF00808.23 XP_665476.1 - 4.9e-15 55.6 0.0 2.1e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phospholip_A2_3 PF09056.11 XP_665476.1 - 0.0097 16.5 4.6 0.041 14.5 4.6 2.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Histone PF00125.24 XP_665476.1 - 0.01 16.2 2.6 0.01 16.2 0.0 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 AAA PF00004.29 XP_665477.1 - 1.7e-49 167.6 0.0 2.9e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 XP_665477.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 XP_665477.1 - 6.4e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 XP_665477.1 - 1e-05 25.3 0.0 3.6e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 XP_665477.1 - 0.00011 22.2 0.1 0.00072 19.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 XP_665477.1 - 0.00045 20.6 0.0 0.15 12.4 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 XP_665477.1 - 0.0011 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 XP_665477.1 - 0.0022 18.0 0.1 0.027 14.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 XP_665477.1 - 0.007 16.3 0.2 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 XP_665477.1 - 0.032 14.6 0.9 0.22 11.9 0.0 2.7 3 1 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 XP_665477.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 XP_665477.1 - 0.043 14.1 0.3 5.9 7.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain TH1 PF04858.13 XP_665478.1 - 4.7e-13 48.7 2.6 1.1e-06 27.7 0.0 4.9 5 0 0 5 5 5 4 TH1 protein Cullin PF00888.22 XP_665479.1 - 1.6e-10 40.3 0.6 1.9e-10 40.0 0.6 1.0 1 0 0 1 1 1 1 Cullin family Yip1 PF04893.17 XP_665480.1 - 3.5e-09 36.6 10.8 4.5e-09 36.2 10.8 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.10 XP_665480.1 - 0.0028 17.4 0.2 0.0075 16.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (Duf2374) zf-met2 PF12907.7 XP_665481.1 - 1.6e-14 53.8 6.5 2.1e-14 53.3 6.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 XP_665481.1 - 1.2e-11 45.3 1.9 1.6e-11 44.8 1.9 1.2 1 0 0 1 1 1 1 4F5 protein family Elf1 PF05129.13 XP_665481.1 - 0.014 15.4 1.7 0.014 15.4 1.7 1.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_12 PF18658.1 XP_665481.1 - 0.044 13.4 1.2 0.061 12.9 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type DNA_topoisoIV PF00521.20 XP_665482.1 - 1.4e-121 406.4 9.3 1.6e-84 284.3 0.0 2.8 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 XP_665482.1 - 2.3e-29 102.2 5.9 2.3e-29 102.2 5.9 2.9 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM Helicase_C PF00271.31 XP_665482.1 - 0.1 12.9 3.0 1.1 9.7 0.0 3.4 3 1 1 4 4 4 0 Helicase conserved C-terminal domain Lzipper-MIP1 PF14389.6 XP_665485.1 - 0.031 14.6 5.9 0.083 13.2 5.9 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF5320 PF17253.2 XP_665485.1 - 0.61 11.2 3.1 20 6.3 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5320) FAM76 PF16046.5 XP_665485.1 - 3.6 6.8 10.4 4.7 6.5 10.4 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 XP_665485.1 - 9.4 6.4 10.8 0.46 10.7 3.4 2.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Proteasom_PSMB PF10508.9 XP_665487.1 - 1.7e-26 92.8 8.6 4.5e-26 91.4 8.6 1.6 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.7 XP_665487.1 - 0.0027 17.8 0.3 0.0027 17.8 0.3 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF5644 PF18712.1 XP_665488.1 - 0.14 12.2 4.3 0.11 12.5 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5644) mCpol PF18182.1 XP_665489.1 - 0.096 13.0 0.5 2.2 8.6 0.1 2.8 2 1 1 3 3 3 0 minimal CRISPR polymerase domain CRCB PF02537.15 XP_665490.1 - 0.11 12.8 0.6 0.2 12.0 0.6 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) Rad51 PF08423.11 XP_665491.1 - 9.3e-12 44.7 0.0 1.1e-11 44.5 0.0 1.2 1 1 0 1 1 1 1 Rad51 RMI2 PF16100.5 XP_665492.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 SNARE PF05739.19 XP_665493.1 - 1.4e-05 25.0 0.6 2.9e-05 24.0 0.6 1.5 1 0 0 1 1 1 1 SNARE domain Lectin_leg-like PF03388.13 XP_665493.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family DTC PF18102.1 XP_665494.1 - 1.9e-28 99.2 0.2 6.2e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 Deltex C-terminal domain WWE PF02825.20 XP_665494.1 - 5.6e-12 46.1 13.9 8.9e-08 32.6 1.6 3.9 3 1 0 3 3 3 2 WWE domain zf-RING_2 PF13639.6 XP_665494.1 - 1.2e-07 31.9 7.9 1.2e-07 31.9 7.9 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 XP_665494.1 - 1.4e-05 24.8 4.8 4.7e-05 23.0 4.8 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 XP_665494.1 - 7.3e-05 22.7 4.5 0.00043 20.2 4.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 XP_665494.1 - 0.00015 22.0 4.9 0.0006 20.0 4.9 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 XP_665494.1 - 0.0012 18.6 9.1 0.0012 18.6 9.1 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 XP_665494.1 - 0.0013 18.5 1.8 0.0038 17.0 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 XP_665494.1 - 0.0024 17.7 9.5 0.0024 17.7 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 XP_665494.1 - 0.0051 16.4 5.5 0.018 14.6 5.5 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 XP_665494.1 - 0.0096 15.8 3.0 0.027 14.3 2.9 1.8 1 1 0 1 1 1 1 zf-RING of BARD1-type protein PHD PF00628.29 XP_665494.1 - 0.02 14.7 5.9 0.059 13.3 5.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 XP_665494.1 - 0.035 14.1 7.1 0.096 12.7 7.1 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 XP_665494.1 - 0.069 13.2 4.2 0.3 11.2 4.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAICAR_synt PF01259.18 XP_665494.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 SAICAR synthetase CAMSAP_CKK PF08683.11 XP_665495.1 - 5.9e-19 68.4 0.2 1e-18 67.6 0.2 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated UPF0114 PF03350.16 XP_665496.1 - 0.092 13.0 0.1 0.15 12.3 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 PH PF00169.29 XP_665497.1 - 6.1e-09 36.3 0.0 2.8e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 XP_665497.1 - 0.00018 21.7 0.0 0.00064 20.0 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 XP_665497.1 - 0.0026 18.1 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 XP_665497.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Porin_3 PF01459.22 XP_665498.1 - 2.9e-27 95.8 0.4 3.7e-27 95.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic porin PAS_12 PF18095.1 XP_665498.1 - 0.048 13.3 0.2 0.09 12.4 0.2 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Stk19 PF10494.9 XP_665499.1 - 2.4e-09 37.2 1.9 1.4e-08 34.7 1.9 2.2 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 HTH_48 PF17906.1 XP_665502.1 - 0.018 15.1 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Spy1 PF11357.8 XP_665502.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Cell cycle regulatory protein DUF4834 PF16118.5 XP_665502.1 - 0.25 12.3 3.1 1 10.3 3.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PHD PF00628.29 XP_665508.1 - 1.8e-13 50.2 4.3 1.8e-13 50.2 4.3 3.0 3 0 0 3 3 3 1 PHD-finger Prok-RING_4 PF14447.6 XP_665508.1 - 5.6e-06 26.1 4.1 5.6e-06 26.1 4.1 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 XP_665508.1 - 2e-05 24.8 4.4 2e-05 24.8 4.4 3.6 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 XP_665508.1 - 3.3e-05 24.1 4.5 3.3e-05 24.1 4.5 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 XP_665508.1 - 9.8e-05 22.1 3.7 9.8e-05 22.1 3.7 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665508.1 - 0.00012 21.8 4.9 0.00012 21.8 4.9 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_665508.1 - 0.00057 19.7 5.1 0.00057 19.7 5.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665508.1 - 0.0041 17.1 4.2 0.0041 17.1 4.2 3.1 4 1 0 4 4 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 XP_665508.1 - 0.094 12.8 11.4 0.044 13.8 1.0 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.6 XP_665508.1 - 0.47 10.0 3.4 0.3 10.7 0.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_6 PF14835.6 XP_665508.1 - 7.4 6.5 6.8 0.67 9.9 1.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 XP_665508.1 - 9.9 6.0 8.0 20 5.0 1.8 2.9 2 0 0 2 2 2 0 RING-like zinc finger OTU PF02338.19 XP_665510.1 - 4.5e-09 36.9 0.0 4.5e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C78 PF07910.13 XP_665510.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C78 Peptidase_C65 PF10275.9 XP_665510.1 - 0.074 12.5 0.0 0.078 12.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase C65 Otubain R3H PF01424.22 XP_665511.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 R3H domain Ribosomal_60s PF00428.19 XP_665512.1 - 1.3e-20 73.7 1.2 1.6e-20 73.5 1.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DEAD PF00270.29 XP_665513.1 - 8.5e-09 35.4 0.1 8.7e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 XP_665513.1 - 0.045 14.0 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain SecA_DEAD PF07517.14 XP_665513.1 - 0.12 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain CDT1_C PF16679.5 XP_665514.1 - 0.33 11.4 3.4 0.36 11.3 1.6 2.1 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Thymidylate_kin PF02223.17 XP_665517.1 - 7.7e-25 87.6 0.0 9.4e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase PDDEXK_7 PF04411.12 XP_665517.1 - 0.034 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily YppF PF14178.6 XP_665518.1 - 0.14 12.0 0.2 4 7.4 0.1 2.6 2 1 0 2 2 2 0 YppF-like protein TPR_8 PF13181.6 XP_665519.1 - 1.4e-06 28.0 1.4 0.055 13.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 XP_665519.1 - 3.2e-06 26.8 4.6 0.043 13.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 XP_665519.1 - 6.9e-06 26.5 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 XP_665519.1 - 4.4e-05 23.5 1.4 0.53 10.4 0.1 3.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 XP_665519.1 - 5.6e-05 23.6 0.1 0.012 16.3 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 XP_665519.1 - 0.00018 21.8 0.0 0.84 10.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 XP_665519.1 - 0.0005 19.9 0.2 0.37 10.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_665519.1 - 0.00096 18.9 0.7 0.063 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 XP_665519.1 - 0.0015 18.2 0.0 0.0092 15.6 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 XP_665519.1 - 0.0035 17.5 0.2 4.2 7.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3791 PF12668.7 XP_665519.1 - 0.026 14.6 1.2 0.1 12.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) ANAPC3 PF12895.7 XP_665519.1 - 0.031 14.5 0.9 0.29 11.4 0.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 XP_665519.1 - 0.033 14.8 0.0 1.6 9.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CttA_N PF18244.1 XP_665519.1 - 1.1 9.7 6.7 0.66 10.4 3.6 2.2 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain PMC2NT PF08066.12 XP_665520.1 - 0.62 10.8 3.0 11 6.8 0.1 3.7 3 0 0 3 3 3 0 PMC2NT (NUC016) domain MFS_1 PF07690.16 XP_665522.1 - 3.1e-11 42.8 10.2 3.8e-11 42.5 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 XP_665522.1 - 9.2e-07 28.0 3.9 3.3e-05 22.9 0.6 2.1 2 0 0 2 2 2 2 MFS_1 like family MMR_HSR1 PF01926.23 XP_665523.1 - 2.8e-15 56.4 0.5 1.1e-13 51.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_665523.1 - 2.1e-09 37.1 0.4 1.8e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 XP_665523.1 - 1.6e-06 28.1 1.1 0.00021 21.3 0.1 2.8 1 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 XP_665523.1 - 0.019 14.5 0.5 3.1 7.3 0.0 3.2 3 1 1 4 4 4 0 Elongation factor Tu GTP binding domain CDC37_N PF03234.14 XP_665523.1 - 0.084 13.8 2.3 0.85 10.5 3.2 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding MeaB PF03308.16 XP_665523.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 XP_665523.1 - 0.18 12.3 1.2 0.67 10.5 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 XP_665523.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF4349 PF14257.6 XP_665523.1 - 0.51 9.7 2.0 1.8 8.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Dynamin_N PF00350.23 XP_665523.1 - 1.1 9.3 7.2 0.26 11.3 0.4 3.2 2 2 0 2 2 2 0 Dynamin family zf-C2H2_2 PF12756.7 XP_665524.1 - 5.4e-25 87.7 11.5 6.6e-24 84.2 1.9 3.1 3 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 XP_665524.1 - 3.8e-07 30.2 1.5 0.0016 18.7 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 XP_665524.1 - 2.7e-05 24.6 2.7 0.0087 16.8 0.2 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 XP_665524.1 - 0.0001 22.5 8.8 0.034 14.6 0.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 XP_665524.1 - 0.0031 17.5 1.9 0.0083 16.1 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 XP_665524.1 - 0.067 13.1 0.4 19 5.2 0.0 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Autoind_bind PF03472.15 XP_665524.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain zf-met PF12874.7 XP_665524.1 - 0.26 11.7 4.1 15 6.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_6 PF18450.1 XP_665524.1 - 0.54 10.0 5.9 1.4 8.6 0.1 2.8 3 0 0 3 3 3 0 Zinc Finger domain NOA36 PF06524.12 XP_665524.1 - 4 6.7 10.9 0.7 9.2 5.0 2.1 1 1 1 2 2 2 0 NOA36 protein Pro_isomerase PF00160.21 XP_665525.1 - 1.3e-42 145.8 0.0 1.5e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCCH_4 PF18044.1 XP_665526.1 - 5.6e-06 26.0 5.9 9.4e-06 25.3 5.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 XP_665526.1 - 5.6e-05 23.1 5.1 0.0001 22.2 5.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 XP_665526.1 - 0.00014 21.7 4.5 0.00026 20.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2971 PF11185.8 XP_665526.1 - 1 10.6 4.6 3.2 9.0 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Streptin-Immun PF11083.8 XP_665527.1 - 0.0042 17.5 2.4 0.36 11.2 0.1 3.6 2 1 1 3 3 3 1 Lantibiotic streptin immunity protein Macscav_rec PF03523.13 XP_665527.1 - 0.14 12.0 1.6 1.4 8.9 0.1 2.7 2 0 0 2 2 2 0 Macrophage scavenger receptor UDPGP PF01704.18 XP_665528.1 - 1.2e-32 113.1 7.6 2e-32 112.4 7.6 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RIC1 PF07064.13 XP_665531.1 - 1.2e-06 28.1 0.0 3.7e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 RIC1 SapB_1 PF05184.15 XP_665531.1 - 0.36 10.9 5.8 7.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 COMPASS-Shg1 PF05205.12 XP_665531.1 - 2.1 9.1 5.4 0.61 10.8 1.7 2.0 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 ATP-synt_C PF00137.21 XP_665533.1 - 2.9e-30 104.4 18.0 6.4e-16 58.5 4.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2990 PF11693.8 XP_665534.1 - 0.56 10.4 2.2 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) COMM_domain PF07258.14 XP_665535.1 - 0.15 12.2 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 COMM domain Ribosomal_S7 PF00177.21 XP_665539.1 - 1.6e-37 128.5 0.7 1.9e-37 128.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e His_Phos_1 PF00300.22 XP_665540.1 - 7.7e-18 64.9 0.0 4.7e-10 39.5 0.0 3.4 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1840 PF08895.11 XP_665542.1 - 0.28 11.5 1.0 0.81 10.0 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3402 PF11882.8 XP_665542.1 - 0.8 8.7 9.0 3.6 6.6 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Med3 PF11593.8 XP_665542.1 - 2.2 7.4 10.3 5.1 6.2 10.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L6 PF00347.23 XP_665544.1 - 6e-28 97.3 2.5 3e-16 59.8 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 IPP-2 PF04979.14 XP_665545.1 - 8.9e-15 55.6 9.7 8.9e-15 55.6 9.7 2.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3403 PF11883.8 XP_665545.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3403) DUF5048 PF16467.5 XP_665546.1 - 0.028 14.7 0.2 4.4 7.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5048) Sin_N PF04801.13 XP_665547.1 - 1.8e-44 152.7 3.2 9.5e-27 94.3 0.1 2.2 2 0 0 2 2 2 2 Sin-like protein conserved region RNA_GG_bind PF10258.9 XP_665548.1 - 7.2e-24 83.6 0.0 1.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF4015 PF13200.6 XP_665548.1 - 0.029 13.4 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Paz_1 PF18349.1 XP_665548.1 - 0.06 13.3 1.2 0.12 12.4 0.1 1.9 1 1 1 2 2 2 0 PAZ domain CTD_bind PF04818.13 XP_665549.1 - 0.014 16.2 0.7 0.055 14.3 0.3 2.3 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Aida_N PF08910.10 XP_665550.1 - 0.62 10.5 5.9 0.38 11.2 0.6 2.5 2 0 0 2 2 2 0 Aida N-terminus CBP_BcsQ PF06564.12 XP_665550.1 - 1.3 8.4 4.9 7.7 5.9 0.9 2.2 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsQ Tctex-1 PF03645.13 XP_665551.1 - 2.8e-25 88.5 1.1 3.4e-25 88.2 1.1 1.1 1 0 0 1 1 1 1 Tctex-1 family KAR PF15222.6 XP_665551.1 - 0.02 15.2 1.4 0.045 14.0 1.0 1.7 1 1 1 2 2 2 0 Kidney androgen-regulated DELLA PF12041.8 XP_665551.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DEAD PF00270.29 XP_665552.1 - 3.4e-40 137.7 0.4 2e-39 135.1 0.1 2.4 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_665552.1 - 4.5e-22 78.5 2.0 2.8e-20 72.7 0.0 3.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 XP_665552.1 - 1.2e-12 47.8 0.1 2.6e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 XP_665552.1 - 0.00035 20.6 6.3 0.00078 19.5 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 XP_665552.1 - 0.0014 17.8 0.1 0.012 14.8 0.0 2.6 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase RNase_J_C PF17770.1 XP_665552.1 - 6.4 7.9 7.6 6.3 7.9 1.0 3.6 4 0 0 4 4 4 0 Ribonuclease J C-terminal domain MMR_HSR1_Xtn PF16897.5 XP_665553.1 - 1.5e-42 143.9 0.3 2.7e-42 143.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 XP_665553.1 - 6e-21 74.7 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 XP_665553.1 - 4.8e-15 55.3 0.0 1.4e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 XP_665553.1 - 4.1e-12 45.9 0.0 8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 XP_665553.1 - 0.00017 21.7 0.1 0.077 13.1 0.0 2.3 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 XP_665553.1 - 0.0038 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 XP_665553.1 - 0.004 16.6 0.3 0.14 11.6 0.1 2.4 1 1 1 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 XP_665553.1 - 0.0047 17.1 0.1 0.13 12.5 0.0 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 XP_665553.1 - 0.023 14.9 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 XP_665553.1 - 0.099 13.2 0.3 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 XP_665553.1 - 0.21 11.5 1.1 1.2 9.0 0.3 2.6 3 1 0 3 3 3 0 RsgA GTPase Spindle_Spc25 PF08234.12 XP_665554.1 - 1.7e-16 60.2 1.8 1.7e-16 60.2 1.8 2.7 2 1 1 3 3 3 1 Chromosome segregation protein Spc25 Apolipoprotein PF01442.18 XP_665554.1 - 0.032 14.1 5.0 0.055 13.4 5.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 XP_665554.1 - 0.14 11.7 3.6 0.18 11.3 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2935 PF11155.8 XP_665554.1 - 1.2 9.5 6.3 3.5 8.0 3.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Noelin-1 PF12308.8 XP_665554.1 - 1.8 8.6 5.4 1.3 9.0 0.2 2.7 2 1 1 3 3 3 0 Neurogenesis glycoprotein Ribosomal_S13 PF00416.22 XP_665554.1 - 2.2 8.7 6.2 1.6 9.2 3.2 1.9 1 1 1 2 2 2 0 Ribosomal protein S13/S18 EF-hand_14 PF17959.1 XP_665554.1 - 9.5 6.7 8.9 0.39 11.1 1.5 2.5 2 1 1 3 3 3 0 EF-hand domain Asn_synthase PF00733.21 XP_665555.1 - 0.00032 20.5 0.3 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 Asparagine synthase Maf1 PF09174.10 XP_665555.1 - 0.0081 16.3 1.4 0.018 15.2 0.2 2.0 2 0 0 2 2 2 1 Maf1 regulator ATP_bind_3 PF01171.20 XP_665555.1 - 0.028 14.2 0.9 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 PP-loop family Chorein_N PF12624.7 XP_665556.1 - 2.2e-22 79.4 3.2 6.7e-22 77.8 1.1 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 XP_665556.1 - 1.1e-09 38.5 5.7 0.00011 22.1 0.3 2.6 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Peptidase_C48 PF02902.19 XP_665558.1 - 2.6e-36 125.5 2.4 3e-36 125.3 2.4 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF2259 PF10016.9 XP_665559.1 - 0.043 13.8 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) TFIIE_alpha PF02002.17 XP_665560.1 - 0.00026 20.8 0.1 0.0021 17.9 0.1 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_Mga PF08280.11 XP_665560.1 - 0.0016 18.4 1.0 0.02 14.9 0.1 2.7 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 XP_665560.1 - 0.0094 15.9 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 XP_665560.1 - 0.0094 15.6 1.4 0.011 15.3 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 XP_665560.1 - 0.017 14.7 0.1 0.053 13.1 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TFIIE-A_C PF11521.8 XP_665560.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Methyltransf_8 PF05148.15 XP_665561.1 - 2.4e-53 181.3 4.4 3.1e-52 177.6 0.1 2.1 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 XP_665561.1 - 4.6e-05 24.0 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_665561.1 - 0.0048 16.7 1.9 0.035 13.9 1.9 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_665561.1 - 0.0085 16.8 0.0 0.031 15.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_665561.1 - 0.042 13.7 0.0 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain FYDLN_acid PF09538.10 XP_665563.1 - 0.024 15.3 2.8 0.024 15.3 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SHNi-TPR PF10516.9 XP_665564.1 - 0.00012 21.5 0.1 0.0009 18.6 0.1 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 XP_665564.1 - 0.00054 19.9 0.1 16 5.9 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SR-25 PF10500.9 XP_665564.1 - 0.03 13.9 19.3 0.059 13.0 19.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 XP_665564.1 - 0.054 11.6 12.6 0.073 11.2 12.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TPR_12 PF13424.6 XP_665564.1 - 0.061 13.6 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat IL4 PF00727.18 XP_665564.1 - 0.071 13.3 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Interleukin 4 DUF357 PF04010.13 XP_665564.1 - 0.23 11.5 3.2 6.9 6.8 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF357) DUF1635 PF07795.11 XP_665564.1 - 0.33 10.8 4.3 0.75 9.6 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SNF2_N PF00176.23 XP_665565.1 - 9.4e-52 175.9 0.1 2.3e-24 85.8 0.0 3.5 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_665565.1 - 8.1e-17 61.6 0.0 8.5e-16 58.3 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_11 PF17123.5 XP_665565.1 - 7.2e-06 25.6 7.0 9.3e-06 25.3 4.4 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 XP_665565.1 - 1.3e-05 25.4 3.6 1.3e-05 25.4 3.6 3.4 4 1 0 4 4 2 1 Ring finger domain zf-C3HC4 PF00097.25 XP_665565.1 - 6.6e-05 22.7 3.6 6.6e-05 22.7 3.6 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_665565.1 - 0.00014 21.6 2.0 0.00014 21.6 2.0 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-PARP PF00645.18 XP_665565.1 - 0.0008 20.2 0.0 0.0008 20.2 0.0 5.3 5 2 1 6 6 4 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-rbx1 PF12678.7 XP_665565.1 - 0.00085 19.6 0.6 0.00085 19.6 0.6 2.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain ResIII PF04851.15 XP_665565.1 - 0.016 15.3 0.0 0.016 15.3 0.0 3.9 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit zf-ANAPC11 PF12861.7 XP_665565.1 - 0.042 13.9 0.8 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 XP_665565.1 - 0.065 13.2 0.6 0.33 10.9 0.6 2.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-RING_UBOX PF13445.6 XP_665565.1 - 0.3 11.1 4.9 0.24 11.4 0.7 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 XP_665565.1 - 0.36 11.2 8.5 0.041 14.2 2.3 2.7 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 XP_665565.1 - 0.44 10.7 5.9 3.3 8.0 3.0 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Di19 PF05605.12 XP_665565.1 - 0.95 9.8 5.8 6.9 7.0 0.1 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Prp31_C PF09785.9 XP_665566.1 - 3.6e-27 95.7 1.5 6.4e-27 94.9 1.5 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 XP_665566.1 - 2.1e-16 60.1 0.3 3.7e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Tsi6 PF18660.1 XP_665566.1 - 0.16 12.1 0.1 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Tsi6 KH_1 PF00013.29 XP_665566.1 - 1.9 8.4 8.8 0.092 12.6 2.0 2.2 2 0 0 2 2 2 0 KH domain DUF1479 PF07350.12 XP_665567.1 - 0.07 11.9 1.0 0.11 11.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Med3 PF11593.8 XP_665567.1 - 0.75 8.9 10.0 0.028 13.6 2.9 2.1 2 1 0 2 2 2 0 Mediator complex subunit 3 fungal PI_PP_I PF18363.1 XP_665567.1 - 2.4 8.4 9.9 1.3 9.2 0.5 4.0 4 1 0 4 4 4 0 Phosphoinositide phosphatase insertion domain TSC22 PF01166.18 XP_665567.1 - 2.9 8.3 10.4 7.1 7.0 1.2 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family C2-set PF05790.15 XP_665567.1 - 5.3 7.3 7.5 0.65 10.2 1.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF3450 PF11932.8 XP_665567.1 - 7.4 5.8 9.4 1.8 7.8 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 XP_665567.1 - 9.6 6.4 17.9 7.3 6.8 6.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SecY PF00344.20 XP_665568.1 - 3.6e-71 239.9 17.3 4.4e-71 239.6 17.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 XP_665568.1 - 1.9e-17 62.8 1.8 3.9e-17 61.8 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p DHHA2 PF02833.14 XP_665570.1 - 6.6e-09 36.1 0.0 7.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 DHHA2 domain RPA_C PF08784.11 XP_665572.1 - 0.018 15.7 1.1 0.032 14.9 0.8 1.6 1 1 0 1 1 1 0 Replication protein A C terminal Sec20 PF03908.13 XP_665573.1 - 3.4e-05 23.7 0.3 5e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 XP_665573.1 - 0.0007 19.4 0.3 0.00083 19.2 0.3 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 ArsR PF09824.9 XP_665573.1 - 0.031 13.9 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator SRP40_C PF05022.12 XP_665574.1 - 3.1e-15 56.8 3.7 3.3e-15 56.7 3.7 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain RRM_1 PF00076.22 XP_665575.1 - 9.8e-13 47.7 0.1 9.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_665575.1 - 1.7e-05 24.6 0.1 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif SUB1_ProdP9 PF18213.1 XP_665575.1 - 0.021 14.6 4.6 1.9 8.4 0.1 2.8 2 1 1 3 3 3 0 SUB1 protease Prodomain ProdP9 DUF5446 PF17522.2 XP_665575.1 - 0.084 13.1 0.8 0.32 11.2 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5446) Hexapep PF00132.24 XP_665576.1 - 3e-15 55.3 20.0 2.5e-05 23.8 4.4 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 XP_665576.1 - 8.4e-06 25.4 20.6 0.00014 21.5 6.1 3.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 XP_665576.1 - 0.0021 16.3 7.0 0.0043 15.3 7.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 XP_665576.1 - 0.027 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.12 XP_665576.1 - 0.044 12.7 7.8 0.16 10.9 7.8 2.0 1 1 0 1 1 1 0 L-fucokinase zf-C2H2_jaz PF12171.8 XP_665578.1 - 2.1e-06 27.9 0.5 5.1e-06 26.6 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 XP_665578.1 - 1.1e-05 25.6 1.9 2.8e-05 24.3 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 XP_665578.1 - 0.011 16.5 0.2 0.026 15.3 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 XP_665578.1 - 0.046 13.8 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.7 XP_665578.1 - 0.054 13.8 0.4 0.1 12.9 0.4 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 XP_665578.1 - 0.12 12.9 0.5 0.25 11.9 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Vps39_2 PF10367.9 XP_665579.1 - 2.1e-20 73.2 2.4 4.3e-20 72.2 0.3 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Cas_CXXC_CXXC PF09706.10 XP_665579.1 - 0.029 14.6 1.3 19 5.6 0.0 3.5 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) SSP160 PF06933.11 XP_665580.1 - 1.1 7.4 15.0 2.5 6.2 15.0 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 dUTPase_2 PF08761.11 XP_665581.1 - 1.2 9.3 5.8 0.3 11.3 0.2 2.6 3 0 0 3 3 3 0 dUTPase Glutaredoxin2_C PF04399.13 XP_665582.1 - 0.067 13.0 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CAF1C_H4-bd PF12265.8 XP_665583.1 - 7.2e-23 80.6 2.4 3.5e-22 78.5 0.7 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 XP_665583.1 - 5.5e-19 68.2 13.4 0.0022 18.8 1.7 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665583.1 - 0.00038 20.7 0.1 3.9 7.9 0.0 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 XP_665583.1 - 0.022 14.6 10.2 3.9 7.3 0.3 4.5 2 2 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_5 PF04998.17 XP_665584.1 - 2.6e-21 76.3 0.1 3.5e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 SDA1 PF05285.12 XP_665584.1 - 0.002 17.6 15.6 0.002 17.6 15.6 2.1 2 0 0 2 2 2 1 SDA1 CDC45 PF02724.14 XP_665584.1 - 0.15 10.3 13.2 0.13 10.6 9.3 2.2 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 XP_665584.1 - 8.6 5.0 14.2 0.31 9.8 5.9 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpb1_5 PF04998.17 XP_665585.1 - 4e-28 98.6 0.0 4.7e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Kazal_2 PF07648.15 XP_665586.1 - 1.8e-43 146.4 68.8 1.3e-08 34.8 0.2 8.4 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 XP_665586.1 - 2.1e-29 101.3 67.5 6.8e-08 32.4 0.3 7.8 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain Methyltransf_10 PF05971.12 XP_665586.1 - 0.078 12.3 0.5 0.12 11.7 0.5 1.2 1 0 0 1 1 1 0 RNA methyltransferase AhpC-TSA PF00578.21 XP_665587.1 - 1.5e-39 134.8 0.0 1.9e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 XP_665587.1 - 3.2e-20 72.3 0.0 3.9e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 XP_665587.1 - 1.9e-12 46.8 0.0 4.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 XP_665587.1 - 0.00033 20.6 0.0 0.00075 19.4 0.0 1.5 2 0 0 2 2 2 1 SCO1/SenC Mto2_bdg PF12808.7 XP_665588.1 - 0.073 13.4 1.0 0.073 13.4 1.0 3.8 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region COMP PF11598.8 XP_665588.1 - 2 8.9 5.8 19 5.8 0.1 3.7 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Glyco_transf_8 PF01501.20 XP_665589.1 - 9.9e-07 28.6 0.4 9.9e-07 28.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 XP_665589.1 - 0.021 14.2 0.1 0.024 14.1 0.1 1.0 1 0 0 1 1 1 0 Glucosyltransferase 24 Sod_Fe_C PF02777.18 XP_665591.1 - 1.4e-36 124.7 0.3 9.5e-36 122.1 0.0 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 XP_665591.1 - 1.8e-29 102.0 0.2 3.9e-29 100.9 0.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Proteasome PF00227.26 XP_665592.1 - 5.7e-26 91.2 0.2 3.2e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit CENP-P PF13096.6 XP_665592.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P FadA PF09403.10 XP_665592.1 - 0.03 14.8 0.4 0.081 13.4 0.2 1.7 1 1 1 2 2 2 0 Adhesion protein FadA GCP_N_terminal PF17681.1 XP_665593.1 - 2.4e-15 57.0 3.3 1.2e-14 54.7 3.3 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 XP_665594.1 - 7.3e-14 51.9 4.2 1.1e-13 51.4 4.2 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal UBX PF00789.20 XP_665596.1 - 3e-09 36.9 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 UBX domain Ribosomal_S5 PF00333.20 XP_665597.1 - 3.6e-26 90.9 1.4 5.6e-26 90.3 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 XP_665597.1 - 1.5e-21 75.6 0.0 2.6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain zf-C3H2C3 PF17122.5 XP_665598.1 - 9.9e-09 35.1 9.9 2.7e-08 33.7 9.9 1.8 1 0 0 1 1 1 1 Zinc-finger Clathrin PF00637.20 XP_665598.1 - 1.9e-07 31.1 4.6 1.9e-07 31.1 4.6 4.5 3 2 1 4 4 4 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 XP_665598.1 - 0.0013 18.6 9.2 0.0035 17.3 9.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 XP_665598.1 - 0.0077 16.0 10.7 0.023 14.5 10.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3895 PF13034.6 XP_665598.1 - 0.024 14.7 1.3 0.79 9.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) zf-ANAPC11 PF12861.7 XP_665598.1 - 0.039 14.0 3.0 0.17 11.9 3.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 XP_665598.1 - 0.074 13.4 7.7 0.24 11.7 7.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF386 PF04074.12 XP_665598.1 - 0.15 11.9 0.9 0.42 10.5 0.6 2.0 1 1 1 2 2 2 0 YhcH/YjgK/YiaL zf-C3HC4 PF00097.25 XP_665598.1 - 1.6 8.7 7.3 15 5.6 7.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mucin PF01456.17 XP_665599.1 - 0.23 11.4 58.9 0.59 10.1 58.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltrans_RNA PF04452.14 XP_665601.1 - 1.5e-23 83.4 0.2 1.5e-17 63.7 0.0 2.1 1 1 1 2 2 2 2 RNA methyltransferase Pico_P2B PF01552.17 XP_665603.1 - 0.14 12.3 3.8 0.15 12.2 0.3 2.4 2 0 0 2 2 2 0 Picornavirus 2B protein Adaptin_N PF01602.20 XP_665607.1 - 7e-37 127.2 21.8 6.9e-36 123.9 21.8 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 XP_665607.1 - 1.4e-19 70.7 6.8 2.1e-19 70.2 0.2 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 XP_665607.1 - 0.0097 16.1 0.0 5.4 7.5 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat NdhO PF11910.8 XP_665607.1 - 0.061 13.5 0.1 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O HEAT_2 PF13646.6 XP_665607.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats E1-E2_ATPase PF00122.20 XP_665608.1 - 1.4e-17 63.8 0.0 8e-17 61.3 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 XP_665608.1 - 2.2e-15 57.5 0.0 3.4e-05 24.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase CBM64 PF18666.1 XP_665608.1 - 0.0066 16.5 0.6 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Carbohydrate-binding module 64 Cation_ATPase_N PF00690.26 XP_665608.1 - 0.031 14.0 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 XP_665608.1 - 0.042 13.9 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Ribosomal_L23 PF00276.20 XP_665609.1 - 0.002 18.4 2.5 0.021 15.2 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L23 zf-AN1 PF01428.16 XP_665612.1 - 8.1e-13 48.3 22.9 2.6e-07 30.7 7.6 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 XP_665612.1 - 1.1e-05 25.6 20.4 7.9e-05 22.9 4.9 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain zf-C5HC2 PF02928.16 XP_665612.1 - 0.00012 22.4 10.7 0.0017 18.7 1.4 2.6 2 0 0 2 2 2 2 C5HC2 zinc finger C1_4 PF07975.12 XP_665612.1 - 1.3 9.3 14.4 3.1 8.1 2.6 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L24e PF01246.20 XP_665614.1 - 3e-26 91.4 0.6 3e-26 91.4 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Es2 PF09751.9 XP_665615.1 - 4.4e-05 23.4 16.5 0.00074 19.4 0.1 2.7 2 1 0 2 2 2 2 Nuclear protein Es2 CHIP_TPR_N PF18391.1 XP_665616.1 - 0.33 11.8 6.2 1.3 9.8 1.3 3.3 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain Apt1 PF10351.9 XP_665617.1 - 1.1 8.0 14.1 1.3 7.8 14.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Collagen PF01391.18 XP_665617.1 - 5 7.0 8.7 2.4 8.0 5.7 2.1 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF4246 PF14033.6 XP_665618.1 - 0.089 11.9 0.3 0.15 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) TP53IP5 PF15331.6 XP_665618.1 - 0.091 12.9 2.3 0.093 12.9 0.2 2.0 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 V-ATPase_H_C PF11698.8 XP_665618.1 - 0.26 11.4 3.4 2.2 8.4 0.1 2.9 3 0 0 3 3 3 0 V-ATPase subunit H AATF-Che1 PF13339.6 XP_665618.1 - 0.53 11.0 4.4 3.9 8.2 0.7 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor AAA_5 PF07728.14 XP_665619.1 - 6.8e-06 26.1 0.0 0.17 11.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 XP_665619.1 - 0.0002 20.9 2.5 0.00038 20.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 XP_665619.1 - 0.0042 16.2 0.0 0.0095 15.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein TniB PF05621.11 XP_665619.1 - 0.015 14.7 0.2 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 XP_665619.1 - 0.017 14.5 0.1 0.063 12.6 0.1 1.9 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 XP_665619.1 - 0.02 14.9 0.3 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 XP_665619.1 - 0.021 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_lid_7 PF17867.1 XP_665619.1 - 0.022 15.0 0.1 0.069 13.4 0.0 1.9 2 0 0 2 2 1 0 Midasin AAA lid domain RsgA_GTPase PF03193.16 XP_665619.1 - 0.022 14.6 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 XP_665619.1 - 0.026 14.9 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 XP_665619.1 - 0.028 14.2 0.1 0.098 12.4 0.1 2.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase Roc PF08477.13 XP_665619.1 - 0.037 14.2 0.1 0.14 12.3 0.1 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 XP_665619.1 - 0.048 14.2 2.8 0.063 13.8 0.0 2.6 2 1 0 2 2 2 0 ABC transporter YfkB PF08756.10 XP_665619.1 - 0.05 13.4 1.0 0.12 12.1 1.0 1.6 1 0 0 1 1 1 0 YfkB-like domain AAA_22 PF13401.6 XP_665619.1 - 0.064 13.5 0.1 0.32 11.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 XP_665619.1 - 0.095 13.1 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 XP_665619.1 - 0.097 12.7 2.8 0.63 10.0 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 XP_665619.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family HVSL PF09749.9 XP_665620.1 - 8.4e-08 32.0 2.1 4.1e-07 29.7 2.1 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein zf-CCCH_4 PF18044.1 XP_665624.1 - 0.0077 16.0 1.6 0.0077 16.0 1.6 3.7 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 XP_665624.1 - 0.011 16.0 0.7 0.028 14.6 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 XP_665624.1 - 0.05 13.5 0.5 0.05 13.5 0.5 4.5 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3638 PF12340.8 XP_665624.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) PRELI PF04707.14 XP_665625.1 - 3.2e-26 92.0 1.8 4.1e-26 91.7 0.2 1.7 2 0 0 2 2 2 1 PRELI-like family DUF5332 PF17266.2 XP_665625.1 - 0.055 13.1 0.7 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5332) Scs3p PF10261.9 XP_665626.1 - 0.077 12.5 0.4 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM YqzE PF14038.6 XP_665627.1 - 2.7 8.1 7.4 5.9 7.0 7.4 1.6 1 0 0 1 1 1 0 YqzE-like protein Hydrolase_3 PF08282.12 XP_665627.1 - 4.4 7.0 10.7 1.7 8.3 7.5 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Sec1 PF00995.23 XP_665628.1 - 5.6e-106 356.0 18.4 6.4e-106 355.9 18.4 1.0 1 0 0 1 1 1 1 Sec1 family DUF4874 PF16173.5 XP_665628.1 - 0.023 14.4 0.1 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) TRAM_LAG1_CLN8 PF03798.16 XP_665629.1 - 8.1e-28 97.5 17.2 8.1e-28 97.5 17.2 1.5 2 0 0 2 2 2 1 TLC domain Pox_E8 PF03394.13 XP_665631.1 - 0.032 13.8 0.8 0.044 13.3 0.8 1.2 1 0 0 1 1 1 0 Poxvirus E8 protein Kin17_mid PF10357.9 XP_665633.1 - 6.5e-39 132.7 7.6 1.1e-38 132.0 7.6 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 XP_665633.1 - 0.0021 18.4 3.8 0.0081 16.5 3.8 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 XP_665633.1 - 0.0046 17.2 3.2 0.015 15.6 3.2 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Nup54_57_C PF18570.1 XP_665633.1 - 0.036 13.6 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Myb_DNA-binding PF00249.31 XP_665636.1 - 2.5e-11 43.6 0.5 1.3e-10 41.3 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_665636.1 - 1.3e-06 28.5 3.5 4.4e-06 26.9 0.0 3.0 2 2 1 3 3 3 1 Myb-like DNA-binding domain SLIDE PF09111.10 XP_665636.1 - 0.0022 18.0 0.1 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 XP_665636.1 - 0.027 14.4 0.1 0.27 11.1 0.0 2.4 3 0 0 3 3 3 0 Myb DNA-binding like SoDot-IcmSS PF16848.5 XP_665638.1 - 0.39 10.7 5.8 0.4 10.6 5.8 1.1 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative Keratin_2_head PF16208.5 XP_665640.1 - 0.054 13.6 35.2 1.8 8.7 29.5 2.7 2 0 0 2 2 2 0 Keratin type II head Hydrolase_4 PF12146.8 XP_665641.1 - 6e-19 68.2 0.0 1.2e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_665641.1 - 4.6e-16 59.2 0.0 6.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 XP_665641.1 - 3.4e-07 31.1 0.0 4.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 XP_665641.1 - 0.00025 20.7 0.5 0.001 18.6 0.5 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 XP_665641.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 XP_665641.1 - 0.004 16.8 0.0 0.0049 16.5 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 XP_665641.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 XP_665641.1 - 0.049 13.2 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Palm_thioest PF02089.15 XP_665641.1 - 0.068 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TbpB_C PF17483.2 XP_665641.1 - 0.068 13.5 0.6 0.32 11.4 0.3 2.2 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B Ndr PF03096.14 XP_665641.1 - 0.086 11.5 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydro_lipase PF04083.16 XP_665641.1 - 0.099 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ran_BP1 PF00638.18 XP_665642.1 - 3.4e-39 133.9 3.5 5.2e-39 133.3 3.5 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 XP_665642.1 - 0.15 12.0 3.9 0.71 9.8 3.9 2.1 1 1 0 1 1 1 0 WH1 domain SAC3_GANP PF03399.16 XP_665644.1 - 1.2e-27 97.1 5.7 3.6e-26 92.2 5.7 2.3 1 1 0 1 1 1 1 SAC3/GANP family ABC_export PF16962.5 XP_665648.1 - 0.23 9.8 0.0 0.34 9.3 0.0 1.1 1 0 0 1 1 1 0 Putative ABC exporter UQ_con PF00179.26 XP_665649.1 - 5.8e-38 129.7 1.0 2.1e-35 121.4 1.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 XP_665649.1 - 0.0041 16.8 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 XP_665649.1 - 0.0051 17.1 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF3336 PF11815.8 XP_665649.1 - 0.079 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) Ribosomal_L16 PF00252.18 XP_665650.1 - 3.9e-42 143.4 0.1 5e-42 143.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AAA PF00004.29 XP_665653.1 - 1.4e-42 145.3 0.0 6.1e-42 143.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 XP_665653.1 - 2.1e-10 40.4 0.0 4.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 XP_665653.1 - 6.4e-10 38.7 0.7 1.3e-09 37.7 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 XP_665653.1 - 1.9e-07 31.4 0.0 4.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 XP_665653.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 XP_665653.1 - 2e-05 24.8 0.2 0.0053 17.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 XP_665653.1 - 2.2e-05 23.7 0.0 3.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 XP_665653.1 - 6.2e-05 23.0 0.4 0.00044 20.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 XP_665653.1 - 6.5e-05 23.4 0.2 0.00083 19.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 XP_665653.1 - 0.0017 18.9 0.0 0.0036 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 XP_665653.1 - 0.0026 17.5 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 XP_665653.1 - 0.0037 17.4 0.0 0.01 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 XP_665653.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 XP_665653.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 XP_665653.1 - 0.0074 15.9 1.0 0.022 14.4 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 XP_665653.1 - 0.008 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 XP_665653.1 - 0.0095 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 XP_665653.1 - 0.013 15.0 0.9 0.45 10.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 XP_665653.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 XP_665653.1 - 0.027 13.8 0.1 0.87 8.9 0.1 2.3 1 1 0 2 2 2 0 KaiC AAA_24 PF13479.6 XP_665653.1 - 0.034 13.9 0.2 0.078 12.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 XP_665653.1 - 0.034 14.1 0.1 0.47 10.4 0.0 2.2 1 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 XP_665653.1 - 0.041 13.7 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 XP_665653.1 - 0.049 13.1 0.1 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 XP_665653.1 - 0.098 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 XP_665653.1 - 0.11 12.2 0.2 0.28 10.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 XP_665653.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 XP_665653.1 - 0.12 12.9 0.0 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 XP_665653.1 - 0.15 11.7 0.1 0.8 9.4 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 XP_665653.1 - 0.16 11.9 0.4 1.5 8.7 0.1 2.6 2 1 0 2 2 2 0 NTPase Parvo_NS1 PF01057.17 XP_665653.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Radical_SAM PF04055.21 XP_665654.1 - 1.3e-08 35.4 0.1 2.9e-07 31.0 0.0 2.9 2 1 0 2 2 2 1 Radical SAM superfamily DUF4252 PF14060.6 XP_665655.1 - 0.0059 16.5 0.1 0.0064 16.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4252) Nsp1_C PF05064.13 XP_665656.1 - 2.9e-12 46.4 2.2 2.9e-12 46.4 2.2 2.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 XP_665656.1 - 0.0024 18.7 25.8 0.0024 18.7 25.8 4.3 2 1 2 4 4 4 2 Nucleoporin FG repeat region Filament PF00038.21 XP_665656.1 - 0.011 15.3 12.1 0.067 12.8 0.5 2.3 2 1 0 2 2 2 0 Intermediate filament protein LOH1CR12 PF10158.9 XP_665656.1 - 0.026 14.5 4.1 2.4 8.2 0.3 2.5 2 1 0 2 2 2 0 Tumour suppressor protein DUF489 PF04356.12 XP_665656.1 - 0.29 11.1 6.0 0.27 11.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF1664 PF07889.12 XP_665656.1 - 0.35 10.9 9.9 0.64 10.1 3.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 XP_665656.1 - 0.8 9.7 12.6 4.9 7.2 0.0 3.8 4 0 0 4 4 4 0 Prefoldin subunit APG6_N PF17675.1 XP_665656.1 - 1.2 9.7 13.0 4.1 7.9 7.7 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Cytokin_check_N PF10407.9 XP_665656.1 - 1.5 8.8 5.0 6.9 6.7 0.7 2.8 2 1 1 3 3 3 0 Cdc14 phosphatase binding protein N-terminus DUF724 PF05266.14 XP_665656.1 - 1.5 8.6 12.8 0.35 10.7 5.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Fez1 PF06818.15 XP_665656.1 - 2.4 8.5 11.1 1.2 9.5 8.3 1.8 1 1 0 1 1 1 0 Fez1 MbeD_MobD PF04899.12 XP_665656.1 - 5.5 7.2 8.8 9.7 6.4 0.9 2.8 3 0 0 3 3 3 0 MbeD/MobD like SKA1 PF07160.12 XP_665656.1 - 6.1 6.6 20.0 6.4 6.5 10.2 2.9 1 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF5320 PF17253.2 XP_665656.1 - 9.7 7.3 5.5 12 7.1 0.1 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5320) PHD PF00628.29 XP_665657.1 - 2.7e-05 24.0 11.9 5.1e-05 23.1 11.9 1.5 1 0 0 1 1 1 1 PHD-finger RRM_1 PF00076.22 XP_665658.1 - 8.6e-17 60.7 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fip1 PF05182.13 XP_665659.1 - 1.2e-08 34.3 0.1 2.3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Fip1 motif MatB PF16449.5 XP_665659.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Fimbrillin MatB AKAP95 PF04988.12 XP_665660.1 - 0.82 9.9 6.9 0.93 9.7 1.0 2.2 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Agglutinin PF07468.11 XP_665662.1 - 0.069 13.3 0.3 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Agglutinin domain ZapB PF06005.12 XP_665663.1 - 0.011 16.2 18.7 0.95 9.9 9.5 3.5 2 1 0 2 2 2 0 Cell division protein ZapB DUF1465 PF07323.12 XP_665663.1 - 0.1 12.4 4.2 0.059 13.2 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) Prefoldin_2 PF01920.20 XP_665663.1 - 0.17 11.8 12.9 0.17 11.8 11.0 2.1 3 0 0 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 XP_665663.1 - 0.28 10.5 5.4 0.45 9.8 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF573 PF04504.14 XP_665663.1 - 0.56 10.9 6.2 0.32 11.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF573 NRBF2 PF08961.10 XP_665663.1 - 0.75 9.4 14.3 3.1 7.3 4.3 2.7 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 XP_665663.1 - 1.1 9.5 10.3 0.38 11.0 1.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 XP_665663.1 - 2.5 8.2 13.9 5.8 7.1 4.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 XP_665663.1 - 7.5 6.4 10.6 16 5.4 1.7 3.1 3 0 0 3 3 3 0 Septum formation initiator YabA PF06156.13 XP_665663.1 - 7.8 7.2 16.0 10 6.8 1.9 3.0 1 1 2 3 3 3 0 Initiation control protein YabA Myb_Cef PF11831.8 XP_665664.1 - 3.4e-18 66.1 3.8 3.4e-18 66.1 3.8 2.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 XP_665664.1 - 6.7e-18 64.6 10.2 8.5e-12 45.1 0.7 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_665664.1 - 2.5e-15 56.5 2.2 1.5e-11 44.4 2.3 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain tRNA_m1G_MT PF01746.21 XP_665665.1 - 6.1e-11 42.4 0.1 6.1e-11 42.4 0.1 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Aida_N PF08910.10 XP_665665.1 - 0.28 11.6 8.1 4.6 7.7 3.7 3.1 3 0 0 3 3 3 0 Aida N-terminus ARD PF03079.14 XP_665665.1 - 0.79 9.9 5.1 2.2 8.5 5.1 1.7 1 0 0 1 1 1 0 ARD/ARD' family DUF3043 PF11241.8 XP_665665.1 - 0.89 9.6 6.1 1.9 8.5 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Kinesin PF00225.23 XP_665666.1 - 2.7e-107 358.6 1.9 2.7e-107 358.6 1.9 2.8 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 XP_665666.1 - 1.5e-24 86.7 0.1 1.5e-24 86.7 0.1 2.8 2 1 1 3 3 3 1 Microtubule binding APG6_N PF17675.1 XP_665666.1 - 2.5 8.6 61.7 0.52 10.8 19.0 4.3 1 1 2 3 3 3 0 Apg6 coiled-coil region HOOK PF05622.12 XP_665666.1 - 5.4 5.0 52.5 0.16 10.1 27.5 2.6 3 0 0 3 3 3 0 HOOK protein DUF3337 PF11816.8 XP_665667.1 - 0.066 13.1 0.1 0.069 13.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Gtr1_RagA PF04670.12 XP_665668.1 - 4.8e-49 166.8 3.3 6.6e-49 166.4 3.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GCR PF02155.15 XP_665669.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.0 1 0 0 1 1 1 0 Glucocorticoid receptor GCP_C_terminal PF04130.13 XP_665670.1 - 3.8e-26 92.3 9.9 1e-25 90.9 9.9 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Sec15 PF04091.12 XP_665671.1 - 0.0067 15.9 1.2 0.014 14.8 0.2 1.8 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF2746 PF10874.8 XP_665671.1 - 0.074 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) LXG PF04740.12 XP_665671.1 - 0.11 12.1 0.1 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Pkinase PF00069.25 XP_665672.1 - 6.3e-46 156.9 0.0 5e-43 147.4 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665672.1 - 4.8e-23 81.8 0.0 1.3e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 XP_665672.1 - 1.2e-05 24.8 0.0 0.018 14.4 0.0 2.3 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 XP_665672.1 - 3.6e-05 22.7 0.0 6.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_665672.1 - 0.13 11.5 0.3 0.26 10.6 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 XP_665673.1 - 8.2e-12 45.3 13.5 1.5e-11 44.4 13.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 XP_665673.1 - 6.1e-09 35.6 8.2 1.1e-08 34.8 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_665673.1 - 1.8e-08 34.1 12.2 3.1e-08 33.3 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665673.1 - 3.7e-08 33.1 11.6 7.5e-08 32.1 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_665673.1 - 4.1e-07 29.9 11.3 1.1e-06 28.5 5.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_665673.1 - 7.5e-07 29.0 9.7 1.4e-06 28.1 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 XP_665673.1 - 8.4e-06 26.0 9.7 2.3e-05 24.6 9.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 XP_665673.1 - 8.8e-06 25.4 8.5 8.8e-06 25.4 8.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 XP_665673.1 - 0.00014 21.6 9.4 0.00029 20.6 9.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 XP_665673.1 - 0.024 14.7 4.9 0.05 13.7 4.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 XP_665673.1 - 0.025 14.4 4.1 0.055 13.3 4.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 XP_665673.1 - 0.38 11.0 12.5 2.9 8.1 12.8 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 XP_665673.1 - 4.5 7.0 9.4 19 5.0 8.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type CAF1C_H4-bd PF12265.8 XP_665676.1 - 1.3e-10 41.4 0.1 7.3e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 XP_665676.1 - 0.0016 19.2 11.8 1.3 10.1 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat HTH_9 PF08221.11 XP_665677.1 - 3.1e-06 27.2 2.6 0.0048 17.0 0.2 4.1 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain UPF0240 PF06784.11 XP_665677.1 - 0.091 12.8 0.7 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) PH PF00169.29 XP_665678.1 - 4.4e-08 33.6 4.8 6e-08 33.2 1.4 2.2 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 XP_665678.1 - 0.0049 17.1 0.7 0.015 15.6 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 XP_665678.1 - 0.16 12.4 3.1 0.14 12.6 0.7 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain CS PF04969.16 XP_665679.1 - 0.014 16.4 0.2 0.1 13.6 0.2 2.5 1 0 0 1 1 1 0 CS domain LCE6A PF15858.5 XP_665679.1 - 0.18 12.6 1.2 0.46 11.3 0.1 2.2 2 0 0 2 2 2 0 Late cornified envelope protein 6A family SWIM PF04434.17 XP_665680.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger DEAD PF00270.29 XP_665681.1 - 4.3e-21 75.5 0.0 6.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 XP_665681.1 - 5.5e-10 39.5 0.1 5.5e-10 39.5 0.1 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 XP_665681.1 - 0.017 14.2 0.1 0.044 12.9 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein PRP38_assoc PF12871.7 XP_665684.1 - 2.8 8.6 37.0 6.3 7.5 37.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ribonuc_red_sm PF00268.21 XP_665685.1 - 5.5e-46 157.3 13.3 1.5e-45 155.8 13.3 1.7 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain Hemocyanin_N PF03722.14 XP_665685.1 - 0.028 15.0 5.4 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain BPD_transp_1 PF00528.22 XP_665687.1 - 0.39 10.4 6.7 0.75 9.5 6.7 1.4 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component GPI2 PF06432.11 XP_665688.1 - 2.9e-48 164.8 21.1 8.1e-48 163.3 21.1 1.6 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase AAA PF00004.29 XP_665689.1 - 6.3e-42 143.1 0.3 6e-41 140.0 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 XP_665689.1 - 2e-14 53.3 0.1 6.2e-14 51.8 0.1 1.9 1 1 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 XP_665689.1 - 4.1e-12 46.0 0.8 1e-11 44.7 0.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 XP_665689.1 - 1.7e-08 34.4 0.0 4.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 XP_665689.1 - 1.9e-06 28.1 0.0 4.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 XP_665689.1 - 1.9e-05 24.9 1.6 0.099 12.9 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 XP_665689.1 - 2.6e-05 24.7 0.1 0.00068 20.1 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 XP_665689.1 - 0.0001 22.3 0.1 0.00046 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 XP_665689.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 XP_665689.1 - 0.00024 21.1 0.0 0.00085 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 XP_665689.1 - 0.00042 20.0 0.6 0.051 13.1 0.2 2.4 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 XP_665689.1 - 0.00045 19.7 1.8 0.16 11.3 0.0 3.0 2 2 1 3 3 3 2 KaiC DUF815 PF05673.13 XP_665689.1 - 0.00045 19.5 0.1 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 XP_665689.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 XP_665689.1 - 0.0011 19.3 3.6 0.0015 18.9 0.1 3.0 3 1 0 3 3 3 1 RNA helicase TIP49 PF06068.13 XP_665689.1 - 0.0019 17.5 0.0 0.0044 16.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 XP_665689.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 XP_665689.1 - 0.0066 16.6 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 XP_665689.1 - 0.017 15.7 0.1 0.074 13.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 XP_665689.1 - 0.021 14.3 1.0 0.075 12.5 0.2 2.2 2 1 0 2 2 2 0 PhoH-like protein TniB PF05621.11 XP_665689.1 - 0.021 14.2 0.0 6.8 6.1 0.0 2.6 1 1 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 XP_665689.1 - 0.025 14.0 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 XP_665689.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 XP_665689.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 XP_665689.1 - 0.069 13.0 0.0 1 9.1 0.0 2.4 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 XP_665689.1 - 0.088 12.7 0.1 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 XP_665689.1 - 0.099 11.9 0.1 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 XP_665689.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_4 PF02390.17 XP_665691.1 - 6.6e-28 97.3 0.1 9.5e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 XP_665691.1 - 4.3e-05 24.1 0.0 5.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 XP_665691.1 - 6.8e-05 22.5 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 XP_665691.1 - 0.00054 19.1 0.0 0.00067 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 XP_665691.1 - 0.0026 17.7 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_665691.1 - 0.0081 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_665691.1 - 0.013 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 XP_665691.1 - 0.015 16.0 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 XP_665691.1 - 0.019 15.7 0.0 0.028 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 XP_665691.1 - 0.032 13.8 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 XP_665691.1 - 0.041 13.2 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 XP_665691.1 - 0.17 11.9 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Dynamitin PF04912.14 XP_665693.1 - 0.011 15.1 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Dynamitin Zw10 PF06248.13 XP_665694.1 - 0.015 13.9 6.4 0.008 14.8 4.5 1.4 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 SesA PF17107.5 XP_665694.1 - 0.018 15.2 3.2 0.27 11.4 2.1 2.4 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases P4Ha_N PF08336.11 XP_665694.1 - 0.09 12.8 4.5 0.043 13.8 2.1 1.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FIN1 PF17300.2 XP_665694.1 - 0.21 11.1 9.1 0.047 13.2 5.3 1.9 1 1 1 2 2 2 0 Filaments in between nuclei protein-1 DUF4007 PF13182.6 XP_665694.1 - 0.28 10.3 8.0 0.47 9.5 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4007) Prefoldin_2 PF01920.20 XP_665694.1 - 0.36 10.8 8.2 0.42 10.6 0.5 2.8 2 1 0 2 2 2 0 Prefoldin subunit DASH_Duo1 PF08651.10 XP_665694.1 - 1.5 8.7 10.9 7.9 6.3 1.7 3.3 3 1 0 3 3 3 0 DASH complex subunit Duo1 DUF3347 PF11827.8 XP_665694.1 - 7.4 6.7 8.2 2.5 8.2 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Sedlin_N PF04628.13 XP_665695.1 - 3.1e-17 62.9 0.0 4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HALZ PF02183.18 XP_665696.1 - 0.067 13.4 1.0 0.29 11.4 1.0 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper GARP PF16731.5 XP_665696.1 - 0.083 12.6 0.8 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma bZIP_1 PF00170.21 XP_665696.1 - 0.12 12.5 3.2 0.14 12.3 0.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor zf-C4H2 PF10146.9 XP_665696.1 - 1.7 8.9 8.0 0.23 11.8 2.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein NAM-associated PF14303.6 XP_665697.1 - 0.012 16.4 8.5 0.012 16.4 8.5 1.8 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain Ndc1_Nup PF09531.10 XP_665697.1 - 0.021 13.5 1.5 0.029 13.1 1.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 XP_665697.1 - 0.022 14.0 17.7 0.03 13.5 17.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 XP_665697.1 - 0.047 11.8 12.4 0.069 11.3 12.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 XP_665697.1 - 0.18 11.8 35.6 0.44 10.5 35.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein HNF-1_N PF04814.13 XP_665697.1 - 0.38 11.3 13.6 0.92 10.1 13.6 1.6 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Otopetrin PF03189.13 XP_665697.1 - 0.73 8.6 5.5 1.1 8.0 5.5 1.4 1 0 0 1 1 1 0 Otopetrin SR-25 PF10500.9 XP_665697.1 - 1.1 8.8 21.5 2.6 7.6 19.0 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 XP_665697.1 - 1.4 8.0 15.5 3.3 6.8 15.5 1.5 1 0 0 1 1 1 0 SprA-related family LAP1C PF05609.12 XP_665697.1 - 1.8 7.6 16.0 0.11 11.6 10.8 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF508 PF04370.12 XP_665697.1 - 2.9 7.6 10.4 3.9 7.2 9.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FAM76 PF16046.5 XP_665697.1 - 3.9 6.8 14.5 0.39 10.0 9.9 1.6 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 XP_665697.1 - 3.9 5.9 20.7 0.012 14.2 10.4 1.8 2 0 0 2 2 2 0 Macoilin family Peptidase_S64 PF08192.11 XP_665697.1 - 4.1 5.8 18.6 0.29 9.6 12.8 1.7 2 0 0 2 2 2 0 Peptidase family S64 EF-hand_1 PF00036.32 XP_665698.1 - 1.4e-13 49.3 0.5 1.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 XP_665698.1 - 1.6e-11 44.5 0.8 2.7e-11 43.7 0.8 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 XP_665698.1 - 6.3e-11 41.3 1.8 9.6e-05 21.7 0.4 2.7 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 XP_665698.1 - 4e-09 36.2 0.6 3.7e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_665698.1 - 3.6e-08 32.7 1.9 0.00073 19.3 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 XP_665698.1 - 8.2e-06 26.1 0.2 1.2e-05 25.6 0.2 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.12 XP_665698.1 - 0.011 15.5 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Lyase_catalyt PF09093.11 XP_665698.1 - 0.016 14.4 0.2 0.017 14.3 0.2 1.0 1 0 0 1 1 1 0 Lyase, catalytic Dockerin_1 PF00404.18 XP_665698.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Dockerin type I domain Haemagg_act PF05860.13 XP_665698.1 - 0.13 12.1 7.8 1.2 9.0 4.1 2.4 1 1 1 2 2 2 0 haemagglutination activity domain Myosin_head PF00063.21 XP_665699.1 - 2.8e-172 574.5 11.6 8.5e-172 572.9 11.6 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) CbiA PF01656.23 XP_665699.1 - 0.011 15.8 0.0 0.15 12.1 0.0 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_lid_6 PF17866.1 XP_665699.1 - 0.059 13.6 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 AAA lid domain Zeta_toxin PF06414.12 XP_665699.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 XP_665699.1 - 0.12 12.7 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ARID PF01388.21 XP_665701.1 - 2.1e-14 54.0 0.4 1.9e-13 50.9 0.0 2.7 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain G10 PF01125.17 XP_665702.1 - 6.4e-59 197.9 8.6 7e-59 197.8 8.6 1.0 1 0 0 1 1 1 1 G10 protein DUF2387 PF09526.10 XP_665702.1 - 9.9 6.4 10.3 2.2 8.5 0.4 2.6 2 1 0 3 3 3 0 Probable metal-binding protein (DUF2387) RNase_T PF00929.24 XP_665703.1 - 0.0059 17.2 0.0 0.0097 16.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease S4 PF01479.25 XP_665704.1 - 1.5e-08 34.2 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 XP_665704.1 - 5.2e-07 30.5 4.9 1e-06 29.5 4.9 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF3915 PF13054.6 XP_665705.1 - 0.038 14.0 3.3 0.088 12.8 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Nexin_C PF08628.12 XP_665705.1 - 0.13 12.8 2.5 2.7 8.6 2.5 2.3 1 1 0 1 1 1 0 Sorting nexin C terminal DUF3113 PF11310.8 XP_665705.1 - 0.48 10.4 2.3 0.7 9.9 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3113) Ureide_permease PF07168.11 XP_665705.1 - 1.6 7.4 4.0 3.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Ureide permease UCH PF00443.29 XP_665706.1 - 1.9e-20 73.4 13.1 5.7e-20 71.9 13.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_665706.1 - 1.7e-06 27.9 13.2 1.8e-05 24.5 13.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 XP_665707.1 - 6.4e-12 45.6 4.9 6.4e-12 45.6 4.9 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 XP_665707.1 - 1.1e-09 37.8 3.5 3.3e-09 36.3 3.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 XP_665707.1 - 1e-08 35.3 3.3 3.3e-08 33.7 3.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 XP_665707.1 - 1.7e-07 30.9 4.1 3.7e-07 29.9 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665707.1 - 1.7e-06 27.8 4.5 4.2e-06 26.5 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_665707.1 - 3.1e-06 27.1 4.4 7.5e-06 25.9 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_665707.1 - 1.3e-05 25.0 3.3 3e-05 23.9 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 XP_665707.1 - 0.00013 21.8 3.2 0.00037 20.3 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 XP_665707.1 - 0.0016 18.2 2.1 0.0036 17.1 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 XP_665707.1 - 0.026 14.1 1.9 0.026 14.1 1.9 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 XP_665707.1 - 0.027 14.3 2.9 0.052 13.4 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 XP_665707.1 - 0.032 14.0 2.8 0.07 12.9 2.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 XP_665707.1 - 0.047 13.7 2.7 0.15 12.2 2.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 XP_665707.1 - 0.13 12.3 1.2 0.24 11.5 1.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger FtsL PF04999.13 XP_665707.1 - 0.21 11.6 1.4 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Cell division protein FtsL FANCL_C PF11793.8 XP_665707.1 - 0.21 11.8 4.4 1.1 9.5 4.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Voltage_CLC PF00654.20 XP_665707.1 - 0.59 9.3 3.3 1.1 8.4 3.3 1.4 1 1 0 1 1 1 0 Voltage gated chloride channel zf-C3HC4_2 PF13923.6 XP_665709.1 - 1.1e-09 37.9 8.0 1.9e-09 37.2 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665709.1 - 4.8e-09 35.9 9.4 8.5e-09 35.2 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_665709.1 - 1.4e-05 25.3 8.0 2.3e-05 24.6 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 XP_665709.1 - 1.7e-05 24.6 5.2 3e-05 23.8 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_665709.1 - 5.3e-05 23.1 9.0 0.0001 22.2 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 XP_665709.1 - 7.7e-05 22.8 7.9 0.00015 21.9 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 XP_665709.1 - 8.1e-05 22.6 8.6 0.00016 21.6 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 XP_665709.1 - 0.0025 17.6 3.5 0.005 16.6 3.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 XP_665709.1 - 0.033 14.1 4.1 0.058 13.3 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RAWUL PF16207.5 XP_665709.1 - 0.036 14.7 0.0 0.19 12.4 0.0 2.1 1 1 1 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-TFIIB PF13453.6 XP_665709.1 - 0.075 12.4 0.6 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc-ribbons_6 PF07191.12 XP_665709.1 - 0.1 12.6 2.5 0.19 11.7 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 XP_665709.1 - 0.35 10.7 6.2 0.13 12.0 2.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 XP_665709.1 - 0.43 10.5 10.3 19 5.2 11.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 XP_665709.1 - 5.7 7.1 7.8 37 4.5 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 XP_665709.1 - 7.1 7.0 9.4 26 5.2 9.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Myb_DNA-bind_6 PF13921.6 XP_665710.1 - 0.0013 19.0 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Hydrolase_3 PF08282.12 XP_665711.1 - 9.1e-43 146.8 0.1 1.3e-42 146.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 XP_665711.1 - 1.4e-15 57.5 0.2 9.1e-12 45.0 0.1 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 XP_665711.1 - 2.6e-06 27.9 0.0 2.2e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 XP_665711.1 - 0.0016 18.6 0.2 0.21 11.7 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 XP_665711.1 - 0.049 14.0 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 XP_665711.1 - 0.059 12.5 0.1 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Trehalose-phosphatase Hydrolase_like PF13242.6 XP_665711.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_hydro_7 PF00840.20 XP_665712.1 - 0.047 12.4 1.6 0.06 12.1 1.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Baculo_PEP_C PF04513.12 XP_665712.1 - 0.06 13.4 1.9 0.12 12.4 1.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 XP_665712.1 - 0.083 11.8 18.5 0.11 11.5 18.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TerY_C PF15616.6 XP_665712.1 - 0.21 11.7 3.0 0.23 11.6 2.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain Perilipin PF03036.16 XP_665712.1 - 0.33 9.9 10.3 0.36 9.8 10.3 1.1 1 0 0 1 1 1 0 Perilipin family Myb_DNA-bind_3 PF12776.7 XP_665712.1 - 0.76 10.8 8.7 0.13 13.3 3.2 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ISG65-75 PF11727.8 XP_665712.1 - 1.1 8.5 11.4 1.7 7.8 11.4 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein Exonuc_VII_L PF02601.15 XP_665712.1 - 1.1 8.7 14.1 1.3 8.5 14.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Allexi_40kDa PF05549.11 XP_665712.1 - 1.2 8.6 6.5 1.4 8.4 5.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein KfrA_N PF11740.8 XP_665712.1 - 1.3 9.7 5.3 0.58 10.9 2.2 1.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term RP-C_C PF11800.8 XP_665712.1 - 1.8 8.6 10.7 1.1 9.4 8.7 1.5 1 1 1 2 2 2 0 Replication protein C C-terminal region DUF3574 PF12098.8 XP_665712.1 - 1.9 8.3 6.2 1.3 8.8 2.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3574) DUF1664 PF07889.12 XP_665712.1 - 1.9 8.6 10.7 0.35 10.9 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 XP_665712.1 - 8.1 5.4 21.9 9.7 5.2 21.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Goodbye PF17109.5 XP_665712.1 - 8.3 6.9 10.2 9.1 6.8 2.9 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Peptidase_M41 PF01434.18 XP_665713.1 - 1.7e-17 63.9 0.1 2e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M41 Diphthami_syn_2 PF01902.17 XP_665714.1 - 4.7e-16 58.9 0.0 8.1e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Apis_Csd PF11671.8 XP_665714.1 - 0.44 10.6 5.3 0.42 10.6 3.3 2.0 2 0 0 2 2 2 0 Complementary sex determiner protein AP2 PF00847.20 XP_665715.1 - 1.1e-06 28.8 0.1 3.4e-06 27.2 0.1 1.9 1 0 0 1 1 1 1 AP2 domain NTF2 PF02136.20 XP_665716.1 - 4.4e-35 120.9 0.2 4.9e-35 120.7 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 XP_665716.1 - 0.053 13.9 0.0 0.068 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4518 PF15008.6 XP_665716.1 - 0.14 11.3 0.4 0.18 10.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) EIF4E-T PF10477.9 XP_665717.1 - 1.3 7.8 4.7 0.2 10.4 0.8 1.5 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Acyltransferase PF01553.21 XP_665718.1 - 6.2e-17 61.5 0.0 5.5e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase MPP6 PF10175.9 XP_665720.1 - 0.045 14.2 0.0 0.056 13.9 0.0 1.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Ribosomal_S17e PF00833.18 XP_665721.1 - 4.1e-56 188.1 0.5 4.7e-56 188.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ank_2 PF12796.7 XP_665722.1 - 4.8e-40 136.0 10.8 5.5e-10 39.7 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_665722.1 - 2.7e-21 75.6 7.9 0.00017 22.0 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 XP_665722.1 - 4.9e-20 71.0 10.7 2.8e-05 24.4 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 XP_665722.1 - 2.9e-18 65.7 6.7 3.9e-05 23.9 0.2 6.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_665722.1 - 2.1e-17 61.4 10.0 0.0022 18.3 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat BAH PF01426.18 XP_665722.1 - 0.0028 17.5 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain Orf78 PF06024.12 XP_665722.1 - 0.11 12.8 8.0 0.79 10.1 0.2 2.8 3 0 0 3 3 3 0 Orf78 (ac78) DUF3953 PF13129.6 XP_665722.1 - 0.12 12.2 1.1 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF2615 PF11027.8 XP_665722.1 - 0.17 12.1 1.3 0.37 11.0 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) DcuA_DcuB PF03605.14 XP_665722.1 - 0.2 10.5 0.1 1.1 8.1 0.1 1.9 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Ribosomal_L7Ae PF01248.26 XP_665723.1 - 2.6e-22 78.4 0.1 3.5e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 XP_665723.1 - 0.022 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Hexapep PF00132.24 XP_665724.1 - 4.8e-10 38.7 10.9 3.2e-07 29.8 2.6 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 XP_665724.1 - 4.4e-05 23.2 12.5 0.0013 18.4 3.3 3.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 XP_665724.1 - 0.00012 21.1 0.8 0.00019 20.5 0.8 1.2 1 0 0 1 1 1 1 L-fucokinase DDHD PF02862.17 XP_665724.1 - 0.12 12.5 3.2 0.16 12.1 3.2 1.1 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 XP_665724.1 - 0.69 9.3 12.1 0.79 9.1 12.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 XP_665724.1 - 4.1 6.6 20.5 6 6.1 20.5 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 XP_665724.1 - 6.2 5.0 12.8 7.5 4.7 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4602 PF15375.6 XP_665725.1 - 2.1e-07 31.3 14.6 7.6e-07 29.5 14.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) WSS_VP PF12175.8 XP_665725.1 - 0.06 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Acid_phosphat_B PF03767.14 XP_665725.1 - 0.27 10.8 4.9 0.4 10.2 4.9 1.5 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ribosomal_L26 PF16906.5 XP_665725.1 - 0.33 11.4 5.4 0.11 13.0 2.1 1.8 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Pet100 PF09803.9 XP_665725.1 - 3 8.4 6.9 16 6.1 6.9 2.3 1 1 0 1 1 1 0 Pet100 DNA_primase_lrg PF04104.14 XP_665726.1 - 2e-10 40.5 1.2 8.3e-10 38.5 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Chalcone_2 PF16035.5 XP_665726.1 - 0.0059 16.4 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Acyltransferase PF01553.21 XP_665727.1 - 8.5e-11 41.6 0.3 2.4e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Acyltransferase DDOST_48kD PF03345.14 XP_665727.1 - 0.0093 14.8 0.6 0.016 14.1 0.6 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Ribosomal_S19 PF00203.21 XP_665729.1 - 0.15 12.0 0.7 4.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein S19 Mu-like_Pro PF10123.9 XP_665729.1 - 0.86 9.1 6.1 1.2 8.6 6.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Sec20 PF03908.13 XP_665729.1 - 1.9 8.5 9.4 0.68 9.9 4.9 2.3 2 0 0 2 2 2 0 Sec20 zf-C2H2_2 PF12756.7 XP_665729.1 - 4.1 7.8 7.0 7.7 6.9 1.9 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) HSP90 PF00183.18 XP_665730.1 - 7.2e-229 761.0 26.8 8.8e-229 760.7 26.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 XP_665730.1 - 4.6e-16 59.3 0.3 8.7e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 XP_665730.1 - 3.8e-11 43.0 0.3 9.9e-11 41.6 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 XP_665730.1 - 0.051 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Tumour suppressor protein DUF4032 PF13224.6 XP_665730.1 - 0.085 12.7 0.0 19 5.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4032) Ribosomal_S20p PF01649.18 XP_665730.1 - 0.67 10.6 3.8 0.46 11.2 0.4 2.5 3 0 0 3 3 3 0 Ribosomal protein S20 MBF1 PF08523.10 XP_665731.1 - 3.1e-19 69.2 0.9 3.1e-19 69.2 0.9 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 XP_665731.1 - 5.6e-13 48.7 0.1 1.1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 XP_665731.1 - 2.4e-05 24.6 0.0 3.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 XP_665731.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 XP_665731.1 - 0.0094 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 XP_665731.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain EF-hand_7 PF13499.6 XP_665732.1 - 3.3e-20 72.3 15.9 2.1e-09 37.7 1.6 4.4 3 2 3 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_665732.1 - 1.2e-17 62.5 9.8 4.5e-05 22.7 0.2 4.8 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 XP_665732.1 - 1.2e-15 55.7 20.8 8.8e-05 21.8 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 XP_665732.1 - 3.9e-14 51.3 18.5 0.002 17.9 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 XP_665732.1 - 6.5e-10 38.7 11.3 0.00022 21.0 0.5 5.8 5 1 1 6 6 6 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 XP_665732.1 - 0.00058 20.2 2.0 0.089 13.1 0.7 3.3 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.11 XP_665732.1 - 0.093 13.2 1.3 0.66 10.5 0.0 2.9 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.6 XP_665732.1 - 0.12 12.3 4.8 2.9 7.8 0.0 3.8 4 0 0 4 4 4 0 EF hand Myb_DNA-binding PF00249.31 XP_665733.1 - 8.1e-13 48.3 0.4 1.6e-12 47.4 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 XP_665733.1 - 0.0003 20.6 0.2 0.00074 19.4 0.2 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 XP_665733.1 - 0.028 14.7 0.2 0.06 13.6 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 XP_665736.1 - 1.7e-29 103.0 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665736.1 - 2.4e-19 69.7 0.0 3.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_665736.1 - 2.2e-10 39.9 1.3 3.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 XP_665736.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 XP_665736.1 - 0.013 14.5 0.3 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 XP_665736.1 - 0.029 13.7 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC3 PF12895.7 XP_665737.1 - 0.0077 16.4 4.4 1.3 9.3 0.2 4.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fungal_trans_2 PF11951.8 XP_665738.1 - 0.0026 16.6 0.5 0.003 16.4 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gtr1_RagA PF04670.12 XP_665739.1 - 9.6e-52 175.6 0.3 1.3e-51 175.2 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 XP_665739.1 - 4e-08 32.9 0.0 7.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 XP_665739.1 - 6.5e-05 22.5 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 XP_665739.1 - 0.0004 20.4 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.10 XP_665739.1 - 0.046 13.2 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FeoB_N PF02421.18 XP_665739.1 - 0.078 12.5 0.5 0.68 9.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Utp12 PF04003.12 XP_665740.1 - 0.00011 22.5 0.3 0.00017 21.9 0.3 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family DNA_pol_phi PF04931.13 XP_665740.1 - 0.034 12.3 44.5 0.05 11.7 44.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 XP_665740.1 - 3.3 5.9 27.5 4.9 5.3 27.5 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 XP_665740.1 - 6.8 5.9 32.7 8.6 5.6 32.7 1.1 1 0 0 1 1 1 0 BUD22 VraX PF17412.2 XP_665741.1 - 1.1 9.0 3.8 0.55 9.9 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function Pkinase PF00069.25 XP_665742.1 - 3.4e-62 210.2 0.1 1.6e-61 208.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 XP_665742.1 - 2.4e-50 168.5 0.9 3.6e-17 62.2 0.0 5.0 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 XP_665742.1 - 4e-29 101.7 0.0 6.6e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_665742.1 - 5.2e-08 32.5 0.0 1.3e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 XP_665742.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tnp_P_element PF12017.8 XP_665742.1 - 0.0072 15.8 0.3 0.029 13.8 0.1 2.1 2 0 0 2 2 2 1 Transposase protein Haspin_kinase PF12330.8 XP_665742.1 - 0.028 13.4 1.5 0.09 11.7 0.1 2.4 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 XP_665742.1 - 0.17 11.2 0.0 0.45 9.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3883 PF13020.6 XP_665743.1 - 1.6e-22 79.3 0.4 3.5e-22 78.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) Steroid_dh PF02544.16 XP_665744.1 - 2.5e-17 63.2 12.6 2.5e-17 63.2 12.6 2.3 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 XP_665744.1 - 0.00072 19.1 1.6 0.0014 18.2 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) RRM_1 PF00076.22 XP_665745.1 - 7.5e-17 60.9 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_665745.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Actin PF00022.19 XP_665746.1 - 3.9e-42 144.3 0.0 2.1e-20 72.8 0.0 2.0 1 1 1 2 2 2 2 Actin CS PF04969.16 XP_665747.1 - 0.00042 21.3 0.9 0.0029 18.6 0.9 2.3 1 1 0 1 1 1 1 CS domain SMC_N PF02463.19 XP_665748.1 - 9.8e-24 84.0 21.7 2.7e-23 82.6 21.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 XP_665748.1 - 8.4e-08 32.5 0.2 2.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 XP_665748.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Csm1_N PF18504.1 XP_665748.1 - 0.049 14.0 0.4 0.049 14.0 0.4 4.8 7 0 0 7 7 7 0 Csm1 N-terminal domain DUF1150 PF06620.11 XP_665748.1 - 0.14 12.3 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) OMPdecase PF00215.24 XP_665749.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Gram_pos_anchor PF00746.21 XP_665749.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Adap_comp_sub PF00928.21 XP_665750.1 - 7.1e-85 284.6 3.5 8.7e-85 284.3 3.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 XP_665750.1 - 7.6e-08 32.4 3.2 1.4e-07 31.5 3.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TSP_1 PF00090.19 XP_665751.1 - 5.1e-07 29.8 43.0 2.9e-05 24.2 5.7 5.3 4 1 0 4 4 4 4 Thrombospondin type 1 domain MMR_HSR1_C PF08438.10 XP_665752.1 - 2.2e-31 108.7 0.5 4.1e-31 107.8 0.5 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 XP_665752.1 - 5.8e-20 71.5 0.0 1.8e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_665752.1 - 4.2e-10 39.4 0.2 3.7e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.17 XP_665752.1 - 0.00015 21.7 0.6 0.079 12.7 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Spore_IV_A PF09547.10 XP_665752.1 - 0.0051 15.8 1.9 0.057 12.3 0.7 2.1 2 0 0 2 2 2 1 Stage IV sporulation protein A (spore_IV_A) GTP_EFTU PF00009.27 XP_665752.1 - 0.0083 15.7 0.1 0.36 10.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 XP_665753.1 - 4e-06 26.6 0.2 0.58 10.0 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_665753.1 - 0.00084 19.1 0.0 1.5 8.7 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Cep57_MT_bd PF06657.13 XP_665754.1 - 0.038 14.4 1.8 0.082 13.4 1.1 1.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Allexi_40kDa PF05549.11 XP_665754.1 - 0.045 13.2 2.4 0.053 13.0 2.2 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein CHASE6_C PF17150.4 XP_665754.1 - 0.066 13.9 0.1 0.095 13.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Gp-FAR-1 PF05823.12 XP_665754.1 - 0.083 13.2 0.8 0.13 12.6 0.8 1.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fzo_mitofusin PF04799.13 XP_665754.1 - 0.091 12.3 3.1 0.11 12.0 2.6 1.4 1 1 1 2 2 2 0 fzo-like conserved region HAUS2 PF15003.6 XP_665754.1 - 0.1 12.3 3.0 0.28 10.9 3.0 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 Prefoldin_2 PF01920.20 XP_665754.1 - 0.12 12.4 5.5 0.46 10.5 5.5 1.9 1 1 0 1 1 1 0 Prefoldin subunit Syntaxin-6_N PF09177.11 XP_665754.1 - 0.21 12.2 3.1 0.27 11.8 3.1 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Muted PF14942.6 XP_665754.1 - 0.25 11.7 5.8 0.28 11.5 5.5 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 XP_665754.1 - 0.28 10.0 7.3 0.47 9.3 7.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 XP_665754.1 - 0.56 8.8 4.7 0.64 8.6 4.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RCC1_2 PF13540.6 XP_665755.1 - 1.6e-08 34.1 4.8 2.8e-06 27.0 0.3 3.1 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 XP_665755.1 - 0.17 12.5 4.1 3.6 8.3 1.8 3.5 2 2 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RPAP3_C PF13877.6 XP_665756.1 - 8.1e-08 32.7 1.7 8.1e-08 32.7 1.7 2.5 3 0 0 3 3 3 1 Potential Monad-binding region of RPAP3 N6_N4_Mtase PF01555.18 XP_665756.1 - 0.01 15.6 0.7 0.029 14.1 0.5 1.8 1 1 0 1 1 1 0 DNA methylase TPR_1 PF00515.28 XP_665756.1 - 0.023 14.5 0.6 0.38 10.7 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HGTP_anticodon PF03129.20 XP_665756.1 - 0.035 14.3 1.5 0.1 12.7 0.9 2.1 2 0 0 2 2 2 0 Anticodon binding domain TPR_2 PF07719.17 XP_665756.1 - 0.2 11.9 1.6 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4119 PF13494.6 XP_665756.1 - 1.5 9.0 6.8 6.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) KHA PF11834.8 XP_665757.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DNA_pol_A_exo1 PF01612.20 XP_665760.1 - 1.4e-37 129.1 0.1 2.5e-37 128.3 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 XP_665760.1 - 1.5e-07 31.3 0.0 4.1e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 HRDC domain PIF1 PF05970.14 XP_665760.1 - 4.1 6.5 8.4 8.1 5.5 4.7 2.2 2 0 0 2 2 2 0 PIF1-like helicase Profilin PF00235.19 XP_665761.1 - 3.2e-22 79.2 1.0 4.7e-22 78.6 1.0 1.2 1 0 0 1 1 1 1 Profilin DIX PF00778.17 XP_665762.1 - 8.6e-12 44.7 0.1 1.3e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 DIX domain Mito_fiss_reg PF05308.11 XP_665762.1 - 0.0029 17.7 9.4 0.0039 17.3 9.4 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator PRIMA1 PF16101.5 XP_665762.1 - 0.017 15.1 14.7 0.03 14.3 14.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DsbG_N PF18257.1 XP_665764.1 - 0.035 14.2 1.0 3.1 8.0 0.0 3.1 1 1 1 3 3 3 0 Disulfide isomerase DsbG N-terminal Fibrillarin PF01269.17 XP_665768.1 - 4.7e-106 353.0 0.0 5.7e-106 352.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 XP_665768.1 - 3.8e-05 23.5 0.0 5.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 XP_665768.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 XP_665768.1 - 0.035 13.8 0.0 0.095 12.3 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 XP_665768.1 - 0.061 12.4 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 XP_665768.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UCH PF00443.29 XP_665769.1 - 2.9e-45 154.8 5.0 2.9e-45 154.8 5.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_665769.1 - 4.9e-21 75.6 8.1 4.9e-21 75.6 8.1 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 XP_665769.1 - 4.1 7.4 8.3 1.7 8.5 0.6 3.2 3 0 0 3 3 3 0 HIT zinc finger Sld3_N PF18523.1 XP_665770.1 - 0.48 10.6 4.5 5.8 7.1 0.5 3.1 2 1 1 3 3 3 0 Sld3 N-terminal domain ABC2_membrane PF01061.24 XP_665771.1 - 8.5e-34 116.8 21.1 8.5e-34 116.8 21.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 XP_665771.1 - 8.1e-24 84.7 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 XP_665771.1 - 6.9e-08 32.0 23.1 6.9e-08 32.0 23.1 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 XP_665771.1 - 1.7e-06 27.6 0.3 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 XP_665771.1 - 1.3e-05 25.2 3.7 0.063 13.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 XP_665771.1 - 0.00037 20.5 0.2 0.00091 19.2 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 XP_665771.1 - 0.00039 20.1 0.1 0.00087 19.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 XP_665771.1 - 0.00095 19.2 0.3 0.0025 17.9 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 XP_665771.1 - 0.0014 19.2 0.2 0.0032 18.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 XP_665771.1 - 0.0016 19.0 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 XP_665771.1 - 0.0025 18.2 0.1 0.0072 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 XP_665771.1 - 0.017 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 XP_665771.1 - 0.022 15.0 0.1 0.06 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 XP_665771.1 - 0.025 13.7 0.1 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 XP_665771.1 - 0.035 13.1 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 XP_665771.1 - 0.043 14.2 0.0 0.27 11.7 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 XP_665771.1 - 0.06 13.4 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 XP_665771.1 - 0.069 12.7 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 XP_665771.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 XP_665771.1 - 0.095 12.9 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 XP_665771.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 XP_665771.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 XP_665771.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 XP_665771.1 - 0.14 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 XP_665771.1 - 0.42 10.5 1.2 0.57 10.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain MaoC_dehydratas PF01575.19 XP_665772.1 - 0.13 11.8 0.0 1.1 8.9 0.0 2.4 3 0 0 3 3 3 0 MaoC like domain Evr1_Alr PF04777.13 XP_665775.1 - 8.5e-06 26.2 0.1 9.2e-06 26.1 0.1 1.0 1 0 0 1 1 1 1 Erv1 / Alr family TPT PF03151.16 XP_665776.1 - 2e-20 73.3 20.0 2.6e-20 73.0 20.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 XP_665776.1 - 2.8e-07 30.8 33.8 0.0018 18.4 10.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 XP_665776.1 - 0.098 11.9 19.4 0.39 9.9 17.0 2.4 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport TMEM234 PF10639.9 XP_665776.1 - 0.16 12.0 5.9 2 8.5 1.4 2.8 2 0 0 2 2 2 0 Putative transmembrane family 234 WD40 PF00400.32 XP_665777.1 - 3.3e-30 103.7 8.1 2e-06 28.4 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665777.1 - 2.5e-09 37.3 0.0 0.0045 17.2 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_665777.1 - 6.5e-05 22.4 0.4 0.00045 19.6 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 XP_665777.1 - 0.0031 16.2 0.3 1.8 7.1 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 SNF2_N PF00176.23 XP_665781.1 - 3.8e-48 164.0 0.9 5.9e-48 163.4 0.9 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_665781.1 - 1.1e-17 64.4 0.0 1e-16 61.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ketoacyl-synt PF00109.26 XP_665783.1 - 1.5e-72 244.3 0.0 8.4e-53 179.5 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 XP_665783.1 - 4.9e-46 156.9 0.0 1.1e-45 155.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 XP_665783.1 - 1.6e-36 124.9 0.0 3.7e-36 123.7 0.0 1.6 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 XP_665783.1 - 1e-21 77.5 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 XP_665783.1 - 2.5e-14 53.4 0.0 5.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 XP_665783.1 - 5.4e-14 52.3 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 XP_665783.1 - 1.1e-09 39.4 0.0 2.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 XP_665783.1 - 6.3e-08 32.3 0.2 5.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 XP_665783.1 - 8.7e-07 28.8 0.5 3.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain KAsynt_C_assoc PF16197.5 XP_665783.1 - 8.5e-06 26.2 0.1 2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension GDP_Man_Dehyd PF16363.5 XP_665783.1 - 0.00036 20.0 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 XP_665783.1 - 0.003 16.9 0.2 0.0086 15.4 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_synt_2 PF02719.15 XP_665783.1 - 0.0046 16.1 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 XP_665783.1 - 0.0058 16.0 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.16 XP_665784.1 - 1.4e-34 119.6 36.8 5.6e-26 91.3 5.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily CPSase_L_D3 PF02787.19 XP_665784.1 - 0.23 11.8 0.7 3.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PepSY_like PF11396.8 XP_665785.1 - 0.017 15.6 1.5 0.065 13.8 0.1 2.2 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like RelB_leu_zip PF16180.5 XP_665785.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 RelB leucine zipper ABC_membrane_2 PF06472.15 XP_665788.1 - 1.8e-36 125.9 3.0 2.6e-36 125.4 3.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 XP_665788.1 - 5.6e-18 65.8 0.0 1.3e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 XP_665788.1 - 4.5e-09 36.2 1.3 1.8e-08 34.2 1.3 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_7 PF12775.7 XP_665788.1 - 0.0006 19.4 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region SMC_N PF02463.19 XP_665788.1 - 0.00079 18.9 0.0 0.0021 17.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 XP_665788.1 - 0.0013 19.3 4.0 0.022 15.3 0.3 2.9 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 XP_665788.1 - 0.0015 18.2 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 XP_665788.1 - 0.0017 18.1 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 XP_665788.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 XP_665788.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 XP_665788.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 XP_665788.1 - 0.015 15.6 0.1 0.34 11.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 XP_665788.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase GPW_gp25 PF04965.14 XP_665788.1 - 0.029 14.1 0.2 0.45 10.3 0.0 2.7 3 0 0 3 3 3 0 Gene 25-like lysozyme AAA_5 PF07728.14 XP_665788.1 - 0.039 14.0 0.1 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 XP_665788.1 - 0.056 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 XP_665788.1 - 0.058 13.6 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 XP_665788.1 - 0.061 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain BUD22 PF09073.10 XP_665790.1 - 0.31 10.3 17.2 0.4 10.0 17.2 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 XP_665790.1 - 0.37 9.6 22.3 0.42 9.4 22.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Paf1 PF03985.13 XP_665790.1 - 0.46 9.4 7.9 0.58 9.1 7.9 1.1 1 0 0 1 1 1 0 Paf1 Sporozoite_P67 PF05642.11 XP_665790.1 - 0.53 8.3 22.9 0.68 7.9 22.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.11 XP_665790.1 - 1.4 9.0 29.5 2.1 8.4 29.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Menin PF05053.13 XP_665790.1 - 2.4 6.4 10.0 2.8 6.2 10.0 1.1 1 0 0 1 1 1 0 Menin Nop14 PF04147.12 XP_665790.1 - 3.2 5.9 11.5 3.9 5.6 11.5 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 XP_665790.1 - 3.8 7.0 7.5 5 6.6 7.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 XP_665790.1 - 4.3 7.1 23.8 5.1 6.9 23.8 1.1 1 0 0 1 1 1 0 SPX domain PI3K_1B_p101 PF10486.9 XP_665790.1 - 4.7 4.9 23.2 5.7 4.6 23.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 XP_665790.1 - 5.8 4.9 9.5 7.5 4.5 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2441 PF10386.9 XP_665792.1 - 0.046 13.7 0.9 0.092 12.7 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) ABC_tran PF00005.27 XP_665793.1 - 1.9e-52 177.4 0.1 1.1e-27 97.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 XP_665793.1 - 1.2e-30 107.1 8.6 1.2e-30 107.1 8.6 1.4 2 0 0 2 2 1 1 ABC transporter transmembrane region SMC_N PF02463.19 XP_665793.1 - 4e-10 39.5 5.7 0.00017 21.1 0.2 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 XP_665793.1 - 5.1e-05 22.9 0.8 0.068 12.9 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 XP_665793.1 - 0.00064 19.8 0.7 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 XP_665793.1 - 0.0039 17.7 0.7 1.5 9.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 XP_665793.1 - 0.0054 17.1 0.4 2.1 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 XP_665793.1 - 0.0074 16.2 0.3 1.1 9.2 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase DUF1691 PF07950.11 XP_665793.1 - 0.028 15.1 0.2 0.07 13.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) T2SSE PF00437.20 XP_665793.1 - 0.041 12.9 0.0 0.81 8.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 XP_665793.1 - 0.08 13.0 3.7 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 XP_665793.1 - 0.083 12.2 0.9 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 XP_665793.1 - 0.12 12.1 0.4 12 5.7 0.3 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 XP_665793.1 - 0.18 11.4 0.6 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 XP_665793.1 - 0.18 11.5 0.4 41 3.8 0.2 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 XP_665793.1 - 0.33 10.1 1.5 18 4.4 0.3 2.6 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 XP_665793.1 - 0.5 10.6 2.0 83 3.4 0.1 3.8 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Morc6_S5 PF17942.1 XP_665794.1 - 1e-06 28.8 0.1 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like Nucleoside_tran PF01733.18 XP_665795.1 - 4.3e-24 85.5 11.9 4.3e-24 85.5 11.9 1.5 2 0 0 2 2 2 1 Nucleoside transporter WD40 PF00400.32 XP_665796.1 - 3.7e-59 195.3 31.7 1.3e-10 41.7 0.0 9.6 8 2 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665796.1 - 1.3e-19 70.3 7.1 0.00092 19.5 0.2 6.2 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 XP_665796.1 - 1.1e-07 31.9 0.2 0.00059 19.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 XP_665796.1 - 1.4e-07 30.9 2.0 0.46 9.4 0.0 5.1 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 XP_665796.1 - 5.3e-07 28.7 6.0 0.15 10.7 0.4 4.9 4 1 0 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.12 XP_665796.1 - 2.9e-06 27.7 0.8 5.9e-06 26.7 0.8 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 XP_665796.1 - 0.0012 18.2 1.7 14 4.9 0.0 4.1 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.21 XP_665796.1 - 0.0016 17.2 2.3 0.38 9.5 0.0 3.9 4 0 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 XP_665796.1 - 0.0047 15.3 0.0 0.36 9.1 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 XP_665796.1 - 0.024 14.6 2.2 2.6 8.1 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 XP_665796.1 - 0.059 12.3 10.7 0.4 9.6 0.0 4.0 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain zf-C3HC4_2 PF13923.6 XP_665797.1 - 3e-09 36.6 11.0 5.5e-09 35.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_665797.1 - 7.8e-07 28.9 11.2 1.1e-06 28.3 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_665797.1 - 4e-06 26.6 11.2 7.1e-06 25.8 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_665797.1 - 2.2e-05 24.7 12.2 3.5e-05 24.0 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 XP_665797.1 - 7.1e-05 22.7 11.3 0.00013 21.8 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 XP_665797.1 - 0.00097 19.1 7.0 0.002 18.1 6.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 XP_665797.1 - 0.022 14.6 6.9 0.035 14.0 6.9 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 XP_665797.1 - 0.11 12.4 6.4 0.25 11.3 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_665797.1 - 0.18 11.7 10.4 0.32 10.9 10.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 XP_665797.1 - 0.21 11.8 8.1 0.47 10.6 8.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 XP_665797.1 - 0.28 11.0 4.9 0.55 10.1 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NADH-PPase PF09297.11 XP_665797.1 - 1.8 8.3 7.2 5.7 6.7 0.9 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-rbx1 PF12678.7 XP_665797.1 - 2 8.8 9.5 3 8.2 8.6 1.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain VPS9 PF02204.18 XP_665798.1 - 3.1e-21 75.5 0.3 7.8e-21 74.2 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ELMO_CED12 PF04727.13 XP_665799.1 - 1.1e-38 133.1 2.0 2.4e-38 132.0 2.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family TERF2_RBM PF16772.5 XP_665801.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Sigma_reg_N PF13800.6 XP_665801.1 - 0.18 12.1 2.7 0.74 10.1 2.7 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Peptidase_C50 PF03568.17 XP_665802.1 - 1.3e-43 149.6 3.9 9e-42 143.6 3.9 2.1 1 1 0 1 1 1 1 Peptidase family C50 DUF3833 PF12915.7 XP_665802.1 - 0.0038 16.8 0.0 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3833) DUF4424 PF14415.6 XP_665803.1 - 0.17 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Ebp2 PF05890.12 XP_665806.1 - 2.9e-33 115.6 17.7 3.1e-33 115.5 17.7 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Dus PF01207.17 XP_665807.1 - 7.7e-39 133.6 0.0 2.1e-28 99.3 0.0 3.9 4 0 0 4 4 4 3 Dihydrouridine synthase (Dus) Pex2_Pex12 PF04757.14 XP_665807.1 - 0.01 15.4 1.0 0.019 14.6 1.0 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Secretin_N_2 PF07655.13 XP_665807.1 - 0.095 13.3 12.7 0.29 11.7 12.7 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Corazonin PF17308.2 XP_665807.1 - 0.84 10.0 11.3 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Pro-corazonin IMCp PF12314.8 XP_665809.1 - 0.0012 19.1 25.6 0.045 14.1 2.9 3.1 1 1 2 3 3 3 3 Inner membrane complex protein Ank_2 PF12796.7 XP_665810.1 - 2.8e-23 82.3 1.5 4.6e-13 49.6 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_665810.1 - 4.8e-20 71.6 0.7 3.9e-09 36.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_665810.1 - 3.2e-18 63.9 0.2 7.6e-05 22.8 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Bromodomain PF00439.25 XP_665810.1 - 3.1e-17 62.4 0.2 7e-17 61.3 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Ank_5 PF13857.6 XP_665810.1 - 9.7e-15 54.5 4.4 1.9e-08 34.4 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 XP_665810.1 - 9.2e-12 44.9 0.0 0.01 16.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat DNA_pol3_tau_5 PF12170.8 XP_665810.1 - 0.029 14.4 0.2 0.06 13.4 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha MSG PF02349.15 XP_665810.1 - 1.2 9.3 4.5 1.1 9.5 0.2 2.7 2 1 0 2 2 2 0 Major surface glycoprotein Ala_racemase_N PF01168.20 XP_665811.1 - 9.3e-14 51.6 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Sigma_1s PF02454.16 XP_665811.1 - 0.1 12.6 0.4 4.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Sigma 1s protein DUF1667 PF07892.11 XP_665811.1 - 0.11 12.5 0.3 5.1 7.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1667) tRNA-synt_1 PF00133.22 XP_665812.1 - 4.3e-17 61.6 0.1 1.8e-14 52.9 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 XP_665812.1 - 8.7e-12 44.5 0.0 1.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 XP_665813.1 - 2.9e-17 62.2 0.1 4.5e-16 58.2 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 XP_665813.1 - 7e-09 35.4 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 XP_665813.1 - 3.1e-07 29.5 0.5 9.5e-06 24.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DUF3078 PF11276.8 XP_665815.1 - 0.018 15.4 0.5 0.048 14.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3078) Halogen_Hydrol PF10112.9 XP_665815.1 - 0.028 14.5 0.6 0.056 13.5 0.6 1.5 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Tubulin PF00091.25 XP_665816.1 - 3.3e-67 226.5 0.0 4.8e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 XP_665816.1 - 9.8e-51 171.2 0.4 2.1e-50 170.1 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 XP_665816.1 - 0.024 14.3 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Sugar_tr PF00083.24 XP_665817.1 - 8.8e-23 80.9 40.1 1.4e-15 57.1 15.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 XP_665817.1 - 4.3e-10 39.0 39.8 3.6e-05 22.9 17.0 3.1 2 2 1 3 3 3 2 Major Facilitator Superfamily Stork_head PF10264.9 XP_665818.1 - 0.0055 16.8 0.2 0.0055 16.8 0.2 3.3 3 1 1 4 4 4 1 Winged helix Storkhead-box1 domain DUF3195 PF11424.8 XP_665818.1 - 0.026 14.6 0.1 0.13 12.3 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) SseB_C PF14581.6 XP_665818.1 - 0.069 13.2 0.0 0.3 11.2 0.0 2.1 1 0 0 1 1 1 0 SseB protein C-terminal domain Gag_spuma PF03276.14 XP_665818.1 - 0.22 9.9 0.1 0.32 9.4 0.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein BTB PF00651.31 XP_665819.1 - 0.0037 17.5 0.5 0.0093 16.2 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain PI31_Prot_N PF11566.8 XP_665820.1 - 0.0041 16.9 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal tRNA-synt_1c PF00749.21 XP_665821.1 - 1.5e-100 336.2 0.1 3.5e-100 334.9 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 XP_665821.1 - 6.8e-35 120.5 0.4 1.4e-34 119.5 0.4 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HEAT PF02985.22 XP_665822.1 - 2.6e-10 39.6 1.3 1.6 9.2 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 XP_665822.1 - 0.00043 20.6 0.0 0.54 10.7 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats Poxvirus_B22R_C PF13168.6 XP_665822.1 - 0.017 14.7 0.0 0.061 12.8 0.0 2.0 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Takusan PF04822.13 XP_665822.1 - 0.46 10.4 5.8 2.3 8.1 0.3 3.0 2 0 0 2 2 2 0 Takusan ubiquitin PF00240.23 XP_665823.1 - 9.8e-09 34.8 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 XP_665823.1 - 0.00032 20.6 4.1 0.00032 20.6 4.1 3.4 3 1 1 4 4 4 2 STI1 domain UBA PF00627.31 XP_665823.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 XP_665823.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 XP_665823.1 - 0.0025 17.7 0.3 0.0077 16.2 0.3 1.8 1 0 0 1 1 1 1 Spore germination GerD central core domain HOIP-UBA PF16678.5 XP_665823.1 - 0.018 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair XPC-binding PF09280.11 XP_665823.1 - 1.9 8.3 12.7 0.36 10.6 0.5 3.9 3 1 1 4 4 4 0 XPC-binding domain Rgp1 PF08737.10 XP_665824.1 - 1.5e-09 37.5 8.7 4.9e-08 32.6 0.9 2.2 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 XP_665824.1 - 0.18 11.9 1.8 0.19 11.8 0.2 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Y_phosphatase3 PF13350.6 XP_665825.1 - 1.1e-21 77.9 0.0 1.4e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 XP_665825.1 - 0.00098 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2164 PF09932.9 XP_665825.1 - 0.11 12.5 0.1 8.1 6.6 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) FH2 PF02181.23 XP_665826.1 - 3e-40 138.5 10.0 3e-40 138.5 10.0 3.3 3 1 1 4 4 4 2 Formin Homology 2 Domain Pkinase PF00069.25 XP_665828.1 - 1.7e-66 224.3 0.0 3.5e-66 223.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665828.1 - 2.2e-30 105.8 0.3 6.3e-29 101.0 0.3 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_665828.1 - 5.3e-08 32.5 0.3 5.2e-07 29.3 0.2 2.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 XP_665828.1 - 0.0088 15.4 0.2 0.017 14.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MIZ PF02891.20 XP_665829.1 - 2.2e-15 56.1 1.7 2.2e-15 56.1 1.7 2.6 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger PHD PF00628.29 XP_665829.1 - 1.5e-05 24.8 12.5 4.3e-05 23.3 3.9 3.2 2 1 0 2 2 2 1 PHD-finger Rho_N PF07498.12 XP_665829.1 - 0.0042 17.0 0.3 0.01 15.8 0.3 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain DUF3337 PF11816.8 XP_665829.1 - 0.018 14.9 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) zf-Nse PF11789.8 XP_665829.1 - 0.15 11.9 1.6 0.53 10.1 1.6 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 XP_665829.1 - 0.22 11.5 11.4 0.027 14.4 4.8 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 XP_665829.1 - 0.29 11.3 4.9 0.18 11.9 2.0 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 XP_665829.1 - 0.94 9.4 10.0 0.041 13.8 3.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras PF00071.22 XP_665830.1 - 0.024 14.2 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Ras family Thioredoxin PF00085.20 XP_665832.1 - 7.8e-14 51.5 0.1 8.5e-14 51.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Brr6_like_C_C PF10104.9 XP_665834.1 - 3.5e-41 140.1 6.9 3.5e-41 140.1 6.9 2.3 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2207 PF09972.9 XP_665834.1 - 0.06 12.1 10.7 0.48 9.1 10.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 XP_665834.1 - 0.13 12.1 3.4 0.4 10.4 0.8 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ESSS PF10183.9 XP_665834.1 - 0.45 10.7 1.5 30 4.9 0.0 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Hydrolase_4 PF12146.8 XP_665836.1 - 2.4e-15 56.5 0.0 3e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_665836.1 - 2.2e-09 37.3 0.2 1.1e-05 25.2 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 XP_665836.1 - 5.4e-09 35.2 0.1 0.026 13.2 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 XP_665836.1 - 1.3e-06 29.2 0.0 3e-06 28.0 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1057 PF06342.12 XP_665836.1 - 0.00021 20.4 0.0 0.00042 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 XP_665836.1 - 0.00037 20.2 0.2 0.004 16.9 0.2 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 XP_665836.1 - 0.00042 19.8 0.0 0.0016 17.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 XP_665836.1 - 0.00057 19.9 0.0 0.89 9.4 0.0 2.5 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 XP_665836.1 - 0.0011 18.6 0.0 0.015 14.8 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 XP_665836.1 - 0.03 14.1 0.1 4.9 6.9 0.0 3.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 XP_665836.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 XP_665836.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold ATG16 PF08614.11 XP_665838.1 - 0.00076 19.8 1.7 0.00087 19.6 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 XP_665838.1 - 0.0035 17.9 2.8 0.0047 17.4 2.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region JAKMIP_CC3 PF16034.5 XP_665838.1 - 0.0048 16.9 2.4 0.0066 16.4 2.4 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain MPS2 PF17060.5 XP_665838.1 - 0.0057 16.0 1.4 0.0067 15.7 1.4 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 DUF3053 PF11254.8 XP_665838.1 - 0.0093 15.6 1.1 0.013 15.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) Laminin_II PF06009.12 XP_665838.1 - 0.058 13.4 2.4 0.087 12.8 2.4 1.2 1 0 0 1 1 1 0 Laminin Domain II PCRF PF03462.18 XP_665838.1 - 0.087 12.7 3.1 0.12 12.2 3.1 1.1 1 0 0 1 1 1 0 PCRF domain DUF2935 PF11155.8 XP_665838.1 - 0.09 13.1 1.2 0.13 12.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Serine_rich PF08824.10 XP_665838.1 - 0.097 12.7 2.9 0.13 12.2 2.9 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain DASH_Spc34 PF08657.10 XP_665838.1 - 0.15 11.8 4.2 0.22 11.3 4.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF1664 PF07889.12 XP_665838.1 - 0.15 12.1 3.5 0.23 11.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 XP_665838.1 - 0.25 12.0 4.0 0.18 12.5 1.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA CREPT PF16566.5 XP_665838.1 - 0.27 11.4 5.1 0.48 10.6 5.1 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 XP_665838.1 - 0.28 11.6 7.8 0.5 10.8 7.8 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Swi5 PF07061.11 XP_665838.1 - 0.3 11.2 6.0 0.4 10.8 0.7 2.4 1 1 1 2 2 2 0 Swi5 DUF3450 PF11932.8 XP_665838.1 - 0.42 9.9 5.7 0.6 9.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APC_N_CC PF16689.5 XP_665838.1 - 0.43 10.7 6.7 1.8 8.7 5.2 2.3 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Ribosomal_L7Ae PF01248.26 XP_665840.1 - 1.1e-21 76.4 0.3 1.7e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 XP_665840.1 - 0.081 13.0 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 TK PF00265.18 XP_665842.1 - 2.6e-55 187.0 0.6 3e-55 186.8 0.6 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.6 XP_665842.1 - 0.0069 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1719 PF08224.11 XP_665842.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) S_locus_glycop PF00954.20 XP_665843.1 - 0.13 12.8 2.2 0.36 11.4 0.3 2.8 2 0 0 2 2 2 0 S-locus glycoprotein domain UPF0020 PF01170.18 XP_665844.1 - 8e-16 58.3 0.0 1.8e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 XP_665844.1 - 4.8e-05 23.2 0.2 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 XP_665844.1 - 0.00031 20.1 0.1 0.0071 15.6 0.0 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 XP_665844.1 - 0.018 14.7 1.7 0.17 11.5 0.1 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase EMG1 PF03587.14 XP_665845.1 - 4.1e-58 196.3 0.2 4.5e-58 196.1 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3314 PF11771.8 XP_665846.1 - 0.25 11.5 2.3 0.49 10.5 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) DUF1411 PF07199.11 XP_665846.1 - 1.1 8.9 15.9 0.062 13.0 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) GIDA PF01134.22 XP_665846.1 - 4.6 6.2 11.9 5.2 6.0 10.9 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A CAP_assoc_N PF14504.6 XP_665847.1 - 0.0055 16.5 1.6 0.083 12.6 0.6 3.1 2 0 0 2 2 2 1 CAP-associated N-terminal PH PF00169.29 XP_665848.1 - 2.1e-06 28.2 1.7 2.1e-06 28.2 1.7 2.2 3 1 0 3 3 3 1 PH domain Mito_carr PF00153.27 XP_665851.1 - 3e-37 126.4 1.9 4e-14 52.3 0.0 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein zf-B_box PF00643.24 XP_665854.1 - 8.5e-10 38.6 14.9 8.4e-08 32.2 1.6 3.3 4 0 0 4 4 4 2 B-box zinc finger PARP PF00644.20 XP_665854.1 - 0.26 10.8 3.3 0.25 10.9 0.7 2.3 3 1 0 3 3 3 0 Poly(ADP-ribose) polymerase catalytic domain FH2 PF02181.23 XP_665855.1 - 4.6e-18 65.5 12.3 4.6e-18 65.5 12.3 2.1 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF3336 PF11815.8 XP_665855.1 - 0.12 12.1 4.7 3 7.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3336) SMC_hinge PF06470.13 XP_665855.1 - 0.24 11.7 0.6 30 5.0 0.0 2.8 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain ATP-synt_F6 PF05511.11 XP_665857.1 - 0.091 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF4957 PF16318.5 XP_665858.1 - 0.042 13.8 3.3 0.049 13.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) Prok-RING_2 PF14445.6 XP_665858.1 - 0.21 11.8 10.8 5.2 7.3 6.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 ATP1G1_PLM_MAT8 PF02038.16 XP_665858.1 - 1.3 8.5 5.3 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family FYVE PF01363.21 XP_665858.1 - 1.6 8.9 16.4 4.5 7.5 15.3 2.3 1 1 1 2 2 2 0 FYVE zinc finger NLE PF08154.12 XP_665859.1 - 2e-13 50.7 0.1 8.5e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.32 XP_665859.1 - 6.1e-09 36.4 5.6 0.036 14.9 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665859.1 - 0.007 16.6 0.1 8.9 6.7 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eRF1_2 PF03464.15 XP_665860.1 - 7.3e-45 152.5 0.0 1.5e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 XP_665860.1 - 5.4e-40 136.4 0.1 1.2e-39 135.2 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 XP_665860.1 - 8.2e-21 74.4 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 XP_665860.1 - 6.5e-10 39.4 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 XP_665860.1 - 2.6e-09 37.4 0.0 4.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 XP_665860.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF5643 PF18705.1 XP_665860.1 - 0.056 13.4 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Fibrinogen_aC PF12160.8 XP_665861.1 - 0.53 10.2 3.4 1.2 9.0 3.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain Peptidase_C1 PF00112.23 XP_665862.1 - 4.2e-38 131.6 3.9 1e-37 130.4 3.9 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 XP_665862.1 - 0.00019 20.3 1.8 0.00038 19.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family OAS1_C PF10421.9 XP_665863.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ABC_tran PF00005.27 XP_665864.1 - 6.3e-19 68.8 0.0 1.1e-18 68.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 XP_665864.1 - 5.6e-05 23.7 0.6 5.6e-05 23.7 0.6 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 XP_665864.1 - 0.00072 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 XP_665864.1 - 0.0009 19.4 1.2 0.0009 19.4 1.2 2.5 2 2 1 3 3 3 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 XP_665864.1 - 0.0021 18.1 0.5 0.0042 17.2 0.6 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5125 PF17163.4 XP_665864.1 - 0.0074 16.5 0.4 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5125) AAA_16 PF13191.6 XP_665864.1 - 0.0078 16.6 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 XP_665864.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_21 PF13304.6 XP_665864.1 - 0.014 15.3 2.9 0.11 12.3 0.7 2.5 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 XP_665864.1 - 0.017 15.0 0.9 0.051 13.5 0.9 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 XP_665864.1 - 0.02 13.7 0.2 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 XP_665864.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 XP_665864.1 - 0.031 13.5 0.2 0.086 12.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain SMC_N PF02463.19 XP_665864.1 - 0.031 13.7 0.2 0.22 10.9 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 XP_665864.1 - 0.032 14.5 0.5 0.37 11.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 XP_665864.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 XP_665864.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 XP_665864.1 - 0.088 12.6 1.4 1.9 8.2 0.5 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PyocinActivator PF11112.8 XP_665864.1 - 0.089 12.9 0.2 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyocin activator protein PrtN AAA_7 PF12775.7 XP_665864.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 XP_665864.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 XP_665864.1 - 0.27 11.7 1.7 0.62 10.5 0.2 2.4 3 1 1 4 4 2 0 RNA helicase Dynamin_N PF00350.23 XP_665864.1 - 3.1 7.8 5.1 0.5 10.4 1.0 2.2 2 1 0 2 2 2 0 Dynamin family Aa_trans PF01490.18 XP_665865.1 - 1.2e-46 159.2 43.7 1.7e-46 158.8 43.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Thymidylat_synt PF00303.19 XP_665866.1 - 8.8e-108 359.5 0.0 1.2e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 XP_665866.1 - 2.5e-33 115.1 0.0 7.1e-33 113.6 0.0 1.7 2 0 0 2 2 2 1 Dihydrofolate reductase DUF5105 PF17118.5 XP_665867.1 - 0.015 15.1 1.2 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) PEPcase PF00311.17 XP_665868.1 - 5.8e-222 739.1 0.0 2.8e-134 449.1 0.0 3.1 3 0 0 3 3 3 3 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 XP_665868.1 - 0.00032 19.3 0.0 0.00088 17.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase HpcH_HpaI PF03328.14 XP_665868.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family LOH1CR12 PF10158.9 XP_665868.1 - 0.68 10.0 5.4 0.22 11.5 0.1 2.9 4 0 0 4 4 4 0 Tumour suppressor protein EF-hand_1 PF00036.32 XP_665869.1 - 1.7e-31 105.4 11.9 7.4e-08 31.4 1.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_665869.1 - 2.6e-28 98.3 9.1 3.6e-14 53.0 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_665869.1 - 2.5e-25 86.2 8.1 3.4e-07 29.7 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 XP_665869.1 - 4.3e-17 61.7 6.7 1.3e-09 37.8 1.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 XP_665869.1 - 8.4e-14 51.6 0.3 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 XP_665869.1 - 9.1e-10 37.6 10.9 0.00085 18.7 1.7 4.6 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.7 XP_665869.1 - 5.6e-05 23.0 3.2 0.17 11.9 0.0 2.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 XP_665869.1 - 0.0001 22.6 2.1 0.21 12.0 0.4 2.8 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 XP_665869.1 - 0.00072 19.5 0.3 2.8 7.8 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein DUF1636 PF07845.11 XP_665869.1 - 0.0038 17.7 0.0 0.16 12.4 0.0 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1636) EF-hand_11 PF08976.11 XP_665869.1 - 0.0061 17.4 0.9 1.3 9.9 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain Gp-FAR-1 PF05823.12 XP_665869.1 - 0.0066 16.8 4.2 0.16 12.3 0.1 2.8 2 1 1 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SurA_N_2 PF13623.6 XP_665869.1 - 0.0098 15.8 2.5 1.1 9.2 0.1 2.7 1 1 1 2 2 2 2 SurA N-terminal domain HTH_40 PF14493.6 XP_665869.1 - 0.035 14.5 4.0 2.7 8.5 0.3 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain DUF4214 PF13946.6 XP_665869.1 - 0.039 14.0 0.0 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) Mst1_SARAH PF11629.8 XP_665869.1 - 0.044 13.9 2.7 0.16 12.0 2.7 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Ribosomal_L12 PF00542.19 XP_665869.1 - 0.073 13.4 2.7 0.17 12.2 0.1 2.6 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain PhetRS_B1 PF18262.1 XP_665869.1 - 0.19 12.0 0.4 0.19 12.0 0.4 2.0 2 1 1 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain TerB PF05099.13 XP_665869.1 - 0.27 11.2 4.7 7.6 6.5 0.1 2.8 1 1 1 3 3 3 0 Tellurite resistance protein TerB EF-hand_10 PF14788.6 XP_665869.1 - 0.28 11.1 4.1 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 EF hand MgtE_N PF03448.17 XP_665869.1 - 1.1 9.9 7.0 0.25 11.9 1.2 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain Robl_LC7 PF03259.17 XP_665873.1 - 0.016 15.0 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Roadblock/LC7 domain Ku_PK_bind PF08785.11 XP_665874.1 - 0.15 12.2 0.4 0.32 11.1 0.4 1.7 1 1 0 1 1 1 0 Ku C terminal domain like Yip1 PF04893.17 XP_665875.1 - 1.1e-05 25.2 15.6 2.6e-05 24.0 15.5 1.7 1 1 0 1 1 1 1 Yip1 domain Ribosomal_L3 PF00297.22 XP_665876.1 - 1e-29 103.7 0.3 1.1e-29 103.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 XP_665877.1 - 1.3e-120 402.8 0.6 1.5e-120 402.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Myb_DNA-binding PF00249.31 XP_665879.1 - 8.8e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CLN3 PF02487.17 XP_665879.1 - 0.41 9.6 2.9 1.7 7.6 2.9 2.1 1 0 0 1 1 1 0 CLN3 protein DEAD PF00270.29 XP_665880.1 - 3e-42 144.4 0.1 5.9e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_665880.1 - 1.4e-21 76.9 0.0 2.2e-20 73.0 0.0 2.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_665880.1 - 0.00075 19.5 1.1 0.028 14.4 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MscL PF01741.18 XP_665880.1 - 0.095 13.0 2.4 0.11 12.8 0.3 2.2 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL tRNA-synt_1c PF00749.21 XP_665881.1 - 2.9e-108 361.5 0.0 3.8e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 XP_665881.1 - 1.1e-36 126.4 0.0 3.8e-36 124.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain zf-CCCH PF00642.24 XP_665882.1 - 8.8e-06 25.5 18.1 7.5e-05 22.5 1.8 4.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 XP_665882.1 - 5.3e-05 23.1 14.3 0.00092 19.2 1.5 3.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 XP_665882.1 - 0.0005 20.4 19.9 0.085 13.4 4.6 3.8 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 XP_665882.1 - 0.24 11.6 9.4 3.2 8.0 1.1 2.9 1 1 1 2 2 2 0 Zinc-finger containing family zf-HC5HC2H_2 PF13832.6 XP_665884.1 - 5e-23 81.4 23.1 4.9e-08 33.1 0.5 6.1 5 1 0 5 5 5 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 XP_665884.1 - 2.4e-10 40.5 7.3 2.1e-06 27.9 1.2 6.1 6 0 0 6 6 6 2 PHD-like zinc-binding domain PHD PF00628.29 XP_665884.1 - 4.4e-09 36.1 44.1 1.3e-06 28.1 3.2 5.1 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.6 XP_665884.1 - 1.2e-08 34.4 27.6 7.5e-06 25.4 2.3 3.3 3 0 0 3 3 3 2 PHD-finger Ank_2 PF12796.7 XP_665885.1 - 3.7e-29 101.1 0.1 7.2e-15 55.4 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_665885.1 - 1.5e-18 66.9 1.2 1.5e-07 31.8 0.1 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 XP_665885.1 - 3.3e-15 55.8 0.4 3.4e-05 24.1 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 XP_665885.1 - 1.1e-14 53.1 2.5 0.00057 20.1 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 XP_665885.1 - 2.1e-13 50.2 0.1 4e-08 33.4 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ribosomal_L35Ae PF01247.18 XP_665886.1 - 9.2e-40 134.7 0.4 1.1e-39 134.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae Hydrolase_4 PF12146.8 XP_665887.1 - 5.8e-11 42.1 0.1 8.4e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_665887.1 - 6e-05 22.8 0.6 0.00018 21.3 0.5 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 XP_665887.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 XP_665887.1 - 0.0049 17.5 0.0 0.0056 17.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF5052 PF16475.5 XP_665887.1 - 0.054 13.1 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) CTV_P6 PF06706.11 XP_665888.1 - 2.7 7.8 4.7 5.3 6.8 0.9 2.9 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein Elf4 PF07011.11 XP_665889.1 - 0.014 15.3 1.8 0.018 14.9 1.6 1.4 1 1 0 1 1 1 0 Early Flowering 4 domain DUF4239 PF14023.6 XP_665889.1 - 0.08 12.7 2.2 0.086 12.6 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) HutP PF09021.11 XP_665889.1 - 0.82 10.0 4.4 0.37 11.1 2.1 1.6 1 1 0 2 2 2 0 HutP DUF1444 PF07285.11 XP_665889.1 - 2.1 7.9 8.2 2.3 7.7 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) RRM_1 PF00076.22 XP_665890.1 - 7.2e-20 70.6 0.0 1.3e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_lysozyme2 PF18013.1 XP_665890.1 - 0.0037 17.3 0.1 0.0055 16.7 0.1 1.3 1 0 0 1 1 1 1 Phage tail lysozyme RRM_7 PF16367.5 XP_665890.1 - 0.027 14.6 0.1 0.079 13.1 0.0 1.9 2 1 0 2 2 2 0 RNA recognition motif Cas_Cas6 PF01881.16 XP_665892.1 - 0.021 15.4 2.5 0.094 13.3 2.5 2.2 1 0 0 1 1 1 0 CRISPR associated protein Cas6 DUF4606 PF15379.6 XP_665892.1 - 0.023 14.9 2.1 0.092 13.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) DUF4990 PF16380.5 XP_665892.1 - 5.5 7.1 7.0 46 4.1 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function AMP-binding PF00501.28 XP_665893.1 - 2.7e-91 306.3 0.0 3.6e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 XP_665893.1 - 2.3e-21 76.5 0.0 9.8e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 XP_665893.1 - 5e-18 64.8 0.1 1.2e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 XP_665894.1 - 3.8e-25 87.7 18.9 9.6e-05 23.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_665894.1 - 7.9e-17 61.3 10.6 1.2e-07 31.9 1.3 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 XP_665894.1 - 5.4e-08 32.9 2.2 0.086 12.7 0.0 3.4 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 XP_665894.1 - 7.6e-05 21.8 0.2 0.048 12.6 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 XP_665894.1 - 0.00022 20.0 2.3 0.1 11.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Frtz PF11768.8 XP_665894.1 - 0.18 10.1 0.1 0.91 7.8 0.1 1.9 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 XP_665894.1 - 1 8.2 7.6 0.067 12.1 1.0 2.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Asp PF00026.23 XP_665895.1 - 6e-21 75.2 6.7 4e-13 49.5 0.6 3.5 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 XP_665895.1 - 9.9e-18 65.0 1.7 9.9e-18 65.0 1.7 3.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 XP_665895.1 - 1.6e-12 47.5 3.5 2.7e-06 27.3 0.0 3.1 4 0 0 4 4 4 2 Xylanase inhibitor C-terminal Pkinase PF00069.25 XP_665896.1 - 8.6e-65 218.7 0.0 2.6e-64 217.1 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665896.1 - 1.3e-32 113.1 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_665896.1 - 8.3e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 XP_665896.1 - 0.00016 20.6 0.0 0.00034 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_665896.1 - 0.0022 17.4 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 XP_665897.1 - 3.2e-28 99.2 6.0 5.4e-28 98.5 0.9 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 XP_665897.1 - 0.052 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) SNF2_N PF00176.23 XP_665898.1 - 1.4e-42 145.7 13.2 7.2e-41 140.1 0.0 3.4 3 0 0 3 3 3 2 SNF2 family N-terminal domain zf-RING_2 PF13639.6 XP_665898.1 - 3.2e-05 24.2 5.2 3.2e-05 24.2 5.2 3.7 5 0 0 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 XP_665898.1 - 9.5e-05 22.3 6.6 0.00032 20.7 6.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_665898.1 - 0.0011 18.8 5.1 0.0011 18.8 5.1 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 XP_665898.1 - 0.0014 18.5 7.6 0.0014 18.5 7.6 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_665898.1 - 0.05 13.5 13.0 0.26 11.2 8.8 3.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 XP_665898.1 - 1.8 8.5 17.4 0.05 13.5 5.2 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 XP_665899.1 - 1.6e-66 224.4 0.0 2e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_665899.1 - 1.1e-31 110.1 0.0 2e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_665899.1 - 9.5e-05 21.8 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 XP_665899.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 XP_665900.1 - 0.032 12.5 30.1 0.037 12.3 30.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 XP_665900.1 - 0.098 12.1 30.5 0.14 11.6 30.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 XP_665900.1 - 0.6 8.1 29.8 0.83 7.7 29.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 XP_665900.1 - 4.5 5.4 27.6 5.6 5.1 27.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Rad51 PF08423.11 XP_665902.1 - 6.8e-120 399.1 0.1 8.4e-120 398.8 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 XP_665902.1 - 4.7e-11 42.6 0.0 7.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 XP_665902.1 - 1.5e-08 34.4 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 XP_665902.1 - 1.8e-05 24.2 1.3 9.4e-05 21.9 1.3 2.2 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 XP_665902.1 - 4.1e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF3853 PF12964.7 XP_665902.1 - 0.018 15.2 0.1 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) AAA_24 PF13479.6 XP_665902.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain PHD PF00628.29 XP_665903.1 - 2.3e-05 24.2 6.1 7.2e-05 22.6 6.1 1.9 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 XP_665903.1 - 0.0082 15.8 2.6 0.014 15.0 2.6 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.6 XP_665903.1 - 0.0098 16.0 4.9 0.019 15.1 4.9 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain Zf_RING PF16744.5 XP_665903.1 - 1.1 9.4 10.1 11 6.2 10.1 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 XP_665903.1 - 1.5 9.0 8.9 4.1 7.6 7.4 2.5 2 1 0 2 2 2 0 PHD-finger Ribosomal_L14 PF00238.19 XP_665904.1 - 6.5e-34 116.6 0.0 7.9e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_2c PF01411.19 XP_665905.1 - 1e-190 634.9 0.2 3.8e-190 633.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 XP_665905.1 - 9.2e-16 57.7 2.4 1.4e-15 57.1 0.3 2.6 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 XP_665905.1 - 5.9e-06 26.7 0.5 2.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 DHHA1 domain DUF3492 PF11997.8 XP_665905.1 - 0.0011 18.8 1.2 2 8.1 0.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3492) STAT_int PF02865.17 XP_665905.1 - 0.52 10.8 5.8 0.2 12.1 0.3 3.1 3 1 2 5 5 5 0 STAT protein, protein interaction domain OrfB_IS605 PF01385.19 XP_665905.1 - 2.7 8.3 6.8 0.58 10.4 1.5 2.5 2 1 0 2 2 2 0 Probable transposase AAA PF00004.29 XP_665906.1 - 0.15 12.4 0.1 0.37 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GIY-YIG PF01541.24 XP_665907.1 - 6.3e-12 45.6 0.4 4.1e-11 43.0 0.0 2.3 1 1 1 2 2 2 1 GIY-YIG catalytic domain Ribosomal_S8e PF01201.22 XP_665907.1 - 0.43 10.7 2.3 1.1 9.4 2.3 1.7 1 1 0 1 1 1 0 Ribosomal protein S8e Peptidase_M16 PF00675.20 XP_665908.1 - 1.9e-22 79.9 2.0 1.2e-20 74.0 0.0 3.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_665908.1 - 6.9e-15 55.5 0.9 2.2e-09 37.6 0.1 3.7 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 XP_665908.1 - 1.1e-12 47.8 1.3 2.3e-12 46.8 1.3 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 GAD PF02938.14 XP_665908.1 - 0.0023 18.1 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 GAD domain Ribosomal_S6e PF01092.19 XP_665909.1 - 7.9e-55 184.2 0.0 1.7e-54 183.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e GCFC PF07842.12 XP_665910.1 - 1.1e-10 41.6 2.1 2.1e-10 40.7 2.1 1.5 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 XP_665910.1 - 2.1e-09 37.1 0.6 4.5e-09 36.1 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 XP_665910.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.4 3 0 0 3 3 3 0 G-patch domain DUF4522 PF15022.6 XP_665910.1 - 2.5 8.4 7.1 0.37 11.1 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Transformer PF06495.11 XP_665911.1 - 4e-05 23.8 21.2 4e-05 23.8 21.2 3.2 2 1 0 3 3 3 1 Fruit fly transformer protein dUTPase PF00692.19 XP_665913.1 - 1.5e-15 57.0 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase G5 PF07501.12 XP_665913.1 - 0.11 12.9 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 G5 domain Podoplanin PF05808.11 XP_665914.1 - 0.00017 21.7 0.1 0.00022 21.4 0.1 1.1 1 0 0 1 1 1 1 Podoplanin TrbL PF04610.14 XP_665914.1 - 0.0026 17.5 0.2 0.0041 16.9 0.1 1.3 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein RIFIN PF02009.16 XP_665914.1 - 0.003 17.5 1.2 0.0036 17.3 1.2 1.0 1 0 0 1 1 1 1 Rifin DUF4690 PF15756.5 XP_665914.1 - 0.027 15.0 0.6 0.055 14.1 0.4 1.5 1 1 1 2 2 2 0 Small Novel Rich in Cartilage Phage_Coat_Gp8 PF05371.12 XP_665914.1 - 0.03 14.1 0.2 0.051 13.3 0.2 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Transposase_22 PF02994.14 XP_665914.1 - 0.055 13.6 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 L1 transposable element RBD-like domain MLANA PF14991.6 XP_665914.1 - 0.21 11.9 1.9 4.1 7.7 0.5 2.2 2 0 0 2 2 2 0 Protein melan-A LRRC37AB_C PF14914.6 XP_665914.1 - 0.38 10.6 9.0 0.18 11.7 5.3 2.0 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain CYYR1 PF10873.8 XP_665914.1 - 0.63 10.5 7.2 1.2 9.5 7.2 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DAG1 PF05454.11 XP_665914.1 - 1.6 8.1 8.5 2.3 7.5 8.5 1.5 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Shisa PF13908.6 XP_665914.1 - 2.7 8.2 14.2 8.6 6.6 14.1 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3236 PF11576.8 XP_665915.1 - 0.53 10.0 4.1 0.5 10.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) PIH1_CS PF18201.1 XP_665915.1 - 0.79 10.2 6.6 0.29 11.6 1.9 2.7 3 1 1 4 4 4 0 PIH1 CS-like domain WIF PF02019.18 XP_665915.1 - 6.3 6.5 8.4 32 4.2 0.2 2.8 2 0 0 2 2 2 0 WIF domain UPF0086 PF01868.16 XP_665916.1 - 1.7e-25 88.8 0.1 8.3e-25 86.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Inhibitor_I69 PF13734.6 XP_665916.1 - 0.077 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Spi protease inhibitor GATA PF00320.27 XP_665918.1 - 8.1e-07 28.6 4.7 3.1e-06 26.7 4.7 2.1 1 0 0 1 1 1 1 GATA zinc finger His_Phos_1 PF00300.22 XP_665919.1 - 7.1e-19 68.3 0.0 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4364 PF14277.6 XP_665919.1 - 0.0086 15.8 0.3 0.015 15.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) His_Phos_2 PF00328.22 XP_665919.1 - 0.042 13.2 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ago_N_1 PF18351.1 XP_665920.1 - 0.55 10.7 3.3 0.95 9.9 0.9 2.6 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain TAXi_N PF14543.6 XP_665921.1 - 3.5e-19 69.7 0.2 6.6e-19 68.8 0.2 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 XP_665921.1 - 1.5e-13 50.9 7.4 2.2e-12 47.0 7.4 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 XP_665921.1 - 0.11 13.1 0.0 2.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 XP_665921.1 - 0.13 12.9 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SMC_N PF02463.19 XP_665922.1 - 6.5e-57 192.5 39.5 1e-28 100.3 25.8 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 XP_665922.1 - 3.6e-19 69.2 0.0 1.4e-18 67.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 XP_665922.1 - 1e-14 55.6 10.1 1e-14 55.6 10.1 7.0 2 2 3 5 5 1 1 AAA domain AAA_15 PF13175.6 XP_665922.1 - 5e-07 29.8 5.5 5e-07 29.8 5.5 5.1 2 2 2 4 4 1 1 AAA ATPase domain Lebercilin PF15619.6 XP_665922.1 - 1.7e-06 27.8 24.8 1.7e-06 27.8 24.8 6.4 2 2 4 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease AAA_21 PF13304.6 XP_665922.1 - 6.7e-06 26.1 34.1 0.00038 20.4 1.0 5.5 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 XP_665922.1 - 0.0002 21.0 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 XP_665922.1 - 0.00077 18.4 19.8 0.00077 18.4 19.8 6.1 2 2 4 7 7 7 3 Spc7 kinetochore protein DUF745 PF05335.13 XP_665922.1 - 0.0065 16.2 4.8 0.0065 16.2 4.8 5.6 3 2 4 7 7 7 1 Protein of unknown function (DUF745) ABC_tran PF00005.27 XP_665922.1 - 0.072 13.6 0.0 0.072 13.6 0.0 5.6 4 2 0 4 4 2 0 ABC transporter FdhE PF04216.12 XP_665922.1 - 0.72 9.7 4.3 1.2 9.0 3.1 2.0 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Bcr-Abl_Oligo PF09036.10 XP_665922.1 - 8 6.5 11.2 14 5.8 0.0 4.5 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain TB2_DP1_HVA22 PF03134.19 XP_665924.1 - 3.9e-06 26.7 4.7 6.1e-06 26.1 4.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Arf PF00025.21 XP_665925.1 - 1.6e-57 193.8 0.3 1.7e-57 193.6 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 XP_665925.1 - 1.7e-12 47.6 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 XP_665925.1 - 5e-11 42.4 0.7 6.8e-06 25.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 XP_665925.1 - 2.9e-09 36.7 0.0 3.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 XP_665925.1 - 4.7e-08 32.7 0.0 5.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 XP_665925.1 - 3.1e-07 30.0 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 XP_665925.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_665925.1 - 0.006 16.1 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 XP_665925.1 - 0.011 15.3 0.0 0.082 12.4 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 XP_665925.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 XP_665925.1 - 0.029 14.0 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.18 XP_665925.1 - 0.063 12.6 0.2 0.97 8.7 0.1 2.1 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Fe_hyd_lg_C PF02906.14 XP_665926.1 - 2e-46 158.6 0.2 1.3e-45 156.0 0.2 2.1 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Trimer_CC PF08954.11 XP_665927.1 - 0.04 13.5 0.2 0.14 11.7 0.2 2.0 1 0 0 1 1 1 0 Trimerisation motif TINF2_N PF14973.6 XP_665930.1 - 0.12 12.7 2.1 0.48 10.8 1.9 2.1 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Glutaredoxin PF00462.24 XP_665932.1 - 3e-13 49.8 0.1 4.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4238 PF14022.6 XP_665933.1 - 0.051 13.1 1.1 0.093 12.2 0.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) Frataxin_Cyay PF01491.16 XP_665933.1 - 0.46 10.6 4.9 0.33 11.1 0.1 2.8 3 1 1 4 4 4 0 Frataxin-like domain RSRP PF17069.5 XP_665934.1 - 0.00052 19.7 29.1 0.00052 19.7 29.1 2.9 3 0 0 3 3 3 1 Arginine/Serine-Rich protein 1 Transformer PF06495.11 XP_665934.1 - 0.0017 18.5 23.9 0.0017 18.5 23.9 3.2 3 0 0 3 3 3 1 Fruit fly transformer protein Phage_Gp23 PF10669.9 XP_665934.1 - 0.0052 17.1 9.4 0.0052 17.1 9.4 5.2 4 2 1 5 5 5 1 Protein gp23 (Bacteriophage A118) Rrn6 PF10214.9 XP_665934.1 - 0.88 8.0 39.7 0.024 13.2 20.6 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Malic_M PF03949.15 XP_665939.1 - 5.6e-86 288.0 0.1 7.6e-86 287.6 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 XP_665939.1 - 3.7e-56 189.8 0.0 6.8e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GHL10 PF02638.15 XP_665939.1 - 0.069 12.2 0.1 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase-like 10 OSK PF17182.4 XP_665940.1 - 0.13 11.5 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 OSK domain Dymeclin PF09742.9 XP_665941.1 - 2.1e-80 270.9 38.6 6.3e-80 269.4 38.6 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DHHC PF01529.20 XP_665942.1 - 3.5e-29 101.6 15.5 3.5e-29 101.6 15.5 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sec62 PF03839.16 XP_665943.1 - 1.3e-28 100.0 1.3 2e-28 99.4 1.3 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 TPR_8 PF13181.6 XP_665944.1 - 3.8e-09 36.0 18.2 0.043 14.0 0.2 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 XP_665944.1 - 8.6e-09 34.8 5.0 0.49 10.5 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 XP_665944.1 - 2.4e-08 34.1 0.8 14 6.6 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 XP_665944.1 - 2.4e-07 30.3 15.4 0.85 9.9 0.0 8.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 XP_665944.1 - 2.9e-05 24.3 3.1 21 5.5 0.0 6.8 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 XP_665944.1 - 3.6e-05 23.8 0.0 0.009 16.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 XP_665944.1 - 7.8e-05 22.3 18.9 0.11 12.4 0.7 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_665944.1 - 0.00023 21.3 11.9 0.029 14.6 0.5 5.7 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 XP_665944.1 - 0.001 19.5 4.1 8.4 7.0 0.0 5.8 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 XP_665944.1 - 0.0062 16.2 2.2 2.6 7.8 0.0 5.1 6 0 0 6 6 6 1 TPR repeat RPN7 PF10602.9 XP_665944.1 - 0.012 15.3 15.9 0.15 11.7 0.6 4.9 4 1 1 5 5 5 0 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 XP_665944.1 - 0.027 14.9 0.1 13 6.2 0.0 2.8 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Arm_3 PF16186.5 XP_665944.1 - 0.065 12.8 0.3 3.4 7.3 0.0 2.9 2 0 0 2 2 2 0 Atypical Arm repeat TPR_10 PF13374.6 XP_665944.1 - 0.2 11.6 0.5 12 5.9 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 XP_665945.1 - 1.5e-13 50.8 0.2 1.9e-13 50.4 0.2 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAP2 PF01569.21 XP_665947.1 - 2.9e-08 33.6 7.4 1.5e-06 28.0 7.4 2.4 1 1 0 1 1 1 1 PAP2 superfamily TPPII_N PF12583.8 XP_665947.1 - 0.049 14.2 0.5 0.078 13.6 0.5 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF212 PF02681.14 XP_665947.1 - 0.16 12.1 1.0 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Divergent PAP2 family BRCA2 PF00634.18 XP_665948.1 - 2.3e-61 203.1 26.2 2.4e-07 30.3 0.2 8.9 9 0 0 9 9 9 8 BRCA2 repeat BRCA-2_OB1 PF09103.10 XP_665948.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Transposase_23 PF03017.14 XP_665948.1 - 1.3 9.0 5.8 66 3.6 0.0 4.7 5 0 0 5 5 5 0 TNP1/EN/SPM transposase HEAT PF02985.22 XP_665949.1 - 0.017 15.3 0.2 1.9 9.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 XP_665949.1 - 0.024 15.0 0.0 1.1 9.7 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats RICTOR_V PF14668.6 XP_665949.1 - 0.034 14.4 0.1 0.074 13.3 0.1 1.7 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Ribosomal_L30 PF00327.20 XP_665950.1 - 1e-17 63.7 1.8 2.9e-17 62.3 1.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 XP_665950.1 - 1.6e-08 34.7 0.9 2.8e-08 33.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_S8 PF00410.19 XP_665951.1 - 2.9e-20 72.5 0.0 4.5e-20 71.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Nop14 PF04147.12 XP_665952.1 - 4.1e-54 184.1 67.8 2.2e-44 152.0 56.7 2.5 2 1 0 2 2 2 2 Nop14-like family SKIP_SNW PF02731.15 XP_665953.1 - 1.3e-55 187.4 3.3 1.3e-55 187.4 3.3 2.4 2 0 0 2 2 2 1 SKIP/SNW domain DUF4619 PF15398.6 XP_665953.1 - 0.12 11.8 9.6 0.23 11.0 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) ADK PF00406.22 XP_665955.1 - 5e-53 179.2 0.0 6.2e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 XP_665955.1 - 6e-25 88.2 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 XP_665955.1 - 4.6e-16 58.5 0.1 9.6e-16 57.5 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 XP_665955.1 - 8.6e-07 29.4 0.4 3.8e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 XP_665955.1 - 0.00049 20.6 0.0 0.0022 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 XP_665955.1 - 0.00095 19.3 0.0 0.0043 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 XP_665955.1 - 0.087 12.2 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 XP_665955.1 - 0.12 12.1 0.0 2.4 7.8 0.1 2.5 3 0 0 3 3 3 0 Thymidylate kinase Cytidylate_kin PF02224.18 XP_665955.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Pro_isomerase PF00160.21 XP_665956.1 - 9e-40 136.5 0.0 1.1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD vATP-synt_AC39 PF01992.16 XP_665957.1 - 1.4e-89 300.9 4.1 2e-89 300.4 4.1 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DER1 PF04511.15 XP_665958.1 - 1e-45 156.0 16.1 1.2e-45 155.9 16.1 1.0 1 0 0 1 1 1 1 Der1-like family DASH_Hsk3 PF08227.11 XP_665961.1 - 0.031 14.6 0.5 0.031 14.6 0.5 3.0 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF4535 PF15054.6 XP_665961.1 - 0.19 11.5 3.2 0.94 9.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4535) Mod_r PF07200.13 XP_665961.1 - 5.1 7.2 36.4 2 8.5 4.3 4.1 1 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein PHD PF00628.29 XP_665962.1 - 1.4e-07 31.3 7.4 3.9e-07 29.9 7.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 XP_665962.1 - 0.005 16.9 9.8 0.017 15.2 9.8 2.0 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 XP_665962.1 - 0.042 14.0 5.5 0.44 10.7 5.5 2.6 1 1 0 1 1 1 0 KIAA1045 RING finger Rhodanese_C PF12368.8 XP_665962.1 - 0.065 13.6 4.7 0.26 11.7 4.7 2.0 1 0 0 1 1 1 0 Rhodanase C-terminal C1_1 PF00130.22 XP_665962.1 - 7.6 6.5 7.1 2.4 8.1 3.5 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.6 XP_665962.1 - 9.9 6.1 7.4 4.4 7.2 4.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF681 PF05080.12 XP_665963.1 - 0.049 14.3 0.0 0.074 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF681) DUF3657 PF12394.8 XP_665963.1 - 0.3 11.6 2.1 9.2 6.9 0.1 2.5 2 1 0 2 2 2 0 Protein FAM135 Ribosomal_L36e PF01158.18 XP_665964.1 - 3.2e-37 126.7 2.6 3.5e-37 126.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.11 XP_665965.1 - 1.6e-30 106.4 0.1 2.6e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Bystin ComR_TPR PF18710.1 XP_665965.1 - 0.0088 15.6 0.5 0.016 14.8 0.5 1.3 1 0 0 1 1 1 1 ComR tetratricopeptide Peptidase_M16_C PF05193.21 XP_665966.1 - 9.3e-07 29.0 0.4 2.5e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain PP2C PF00481.21 XP_665967.1 - 8e-46 156.8 0.0 1.3e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 XP_665967.1 - 2.4e-05 24.3 0.0 7.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 XP_665967.1 - 0.00034 20.3 0.0 0.0033 17.1 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C AlaDh_PNT_C PF01262.21 XP_665968.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MARVEL PF01284.23 XP_665970.1 - 1.1 9.3 11.8 0.21 11.6 7.8 1.7 2 0 0 2 2 2 0 Membrane-associating domain DUF4366 PF14283.6 XP_665971.1 - 0.0055 16.8 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) RPN2_C PF18004.1 XP_665972.1 - 1.6e-29 102.9 5.7 1.6e-29 102.9 5.7 3.1 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 XP_665972.1 - 1.7e-29 100.7 16.7 0.0012 19.2 0.4 9.9 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 XP_665972.1 - 1.5e-19 70.1 0.0 5.1e-13 49.2 0.0 6.0 5 1 2 7 7 7 2 HEAT repeats HEAT PF02985.22 XP_665972.1 - 1.9e-05 24.5 0.1 0.54 10.7 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 XP_665972.1 - 0.00025 21.5 0.1 0.049 14.1 0.0 4.3 6 0 0 6 6 6 1 HEAT-like repeat TPR_12 PF13424.6 XP_665972.1 - 0.058 13.7 0.1 0.41 11.0 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 XP_665972.1 - 0.093 12.9 1.1 1.5 9.1 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 XP_665972.1 - 0.18 11.7 1.5 1.8 8.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_665972.1 - 0.22 11.8 3.3 1.1 9.5 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Myosin_tail_1 PF01576.19 XP_665973.1 - 0.043 11.6 10.2 0.05 11.4 10.2 1.0 1 0 0 1 1 1 0 Myosin tail CCDC92 PF14916.6 XP_665973.1 - 0.069 12.9 0.4 0.069 12.9 0.4 2.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF836 PF05768.14 XP_665973.1 - 0.12 12.8 7.1 0.082 13.3 4.8 1.9 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) Jnk-SapK_ap_N PF09744.9 XP_665973.1 - 0.16 12.2 14.7 1.4 9.1 14.7 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 YlqD PF11068.8 XP_665973.1 - 1.2 9.6 9.8 0.49 10.8 6.5 1.8 1 1 1 2 2 2 0 YlqD protein Nmad5 PF18757.1 XP_665973.1 - 1.2 9.3 8.9 1.4 9.1 8.9 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 DUF745 PF05335.13 XP_665973.1 - 1.2 8.8 4.9 1.8 8.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF730 PF05325.11 XP_665973.1 - 1.5 8.9 5.6 2 8.5 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF730) bZIP_1 PF00170.21 XP_665973.1 - 1.6 8.9 18.0 1.6 8.9 0.9 3.3 3 0 0 3 3 3 0 bZIP transcription factor CENP-H PF05837.12 XP_665973.1 - 6.9 7.1 12.2 32 5.0 0.7 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Lipoprotein_2 PF00921.17 XP_665973.1 - 7.5 6.0 8.5 3.1 7.3 1.5 1.9 1 1 1 2 2 2 0 Borrelia lipoprotein Exonuc_VII_L PF02601.15 XP_665973.1 - 9.5 5.7 8.5 11 5.5 8.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cwf_Cwc_15 PF04889.12 XP_665974.1 - 0.0043 16.8 4.4 0.0043 16.8 4.4 2.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein OCRE PF17780.1 XP_665975.1 - 4.8e-13 48.9 0.1 8.6 6.5 0.0 10.1 11 0 0 11 11 11 4 OCRE domain LrgA PF03788.14 XP_665975.1 - 0.082 12.9 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 LrgA family Plectin PF00681.20 XP_665975.1 - 7.6 6.5 17.9 39 4.2 0.0 8.5 11 0 0 11 11 11 0 Plectin repeat RCC1_2 PF13540.6 XP_665976.1 - 0.00013 21.6 5.1 0.082 12.7 0.0 4.5 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat TFA2_Winged_2 PF18121.1 XP_665976.1 - 0.84 9.4 4.9 0.19 11.4 0.7 2.2 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 ArAE_2_N PF10337.9 XP_665976.1 - 1.2 8.1 8.8 2.5 7.1 8.8 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2001 PF09393.10 XP_665977.1 - 0.014 15.4 0.2 0.043 13.8 0.2 1.8 1 0 0 1 1 1 0 Phage tail tube protein DDE_Tnp_IS66 PF03050.14 XP_665977.1 - 0.1 12.1 3.7 0.058 12.9 0.6 1.9 1 1 0 2 2 2 0 Transposase IS66 family PMC2NT PF08066.12 XP_665977.1 - 0.1 13.3 0.7 0.1 13.3 0.7 4.0 3 1 0 4 4 4 0 PMC2NT (NUC016) domain SYCP2_SLD PF18584.1 XP_665977.1 - 0.26 11.5 7.6 0.68 10.2 0.7 2.9 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain YvrJ PF12841.7 XP_665977.1 - 1.4 8.5 3.5 1.9 8.1 0.2 3.0 3 0 0 3 3 3 0 YvrJ protein family DKCLD PF08068.12 XP_665978.1 - 2.6e-32 110.7 0.2 2.5e-31 107.5 0.5 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 XP_665978.1 - 1.7e-22 80.4 0.1 3.4e-19 69.7 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 XP_665978.1 - 6.3e-21 74.3 1.3 1.1e-20 73.5 1.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 XP_665978.1 - 6.5e-20 70.9 2.8 1.5e-19 69.7 2.8 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 XP_665978.1 - 0.022 15.0 0.1 0.073 13.3 0.1 2.0 1 0 0 1 1 1 0 UPF0113 PUA domain SR-25 PF10500.9 XP_665978.1 - 0.079 12.6 46.0 0.12 11.9 46.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4746 PF15928.5 XP_665978.1 - 1.9 7.9 8.1 3.5 7.0 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Macoilin PF09726.9 XP_665978.1 - 7.3 5.0 25.3 10 4.5 25.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF936 PF06075.12 XP_665978.1 - 7.8 5.3 25.9 9.7 5.0 25.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Nuf2 PF03800.14 XP_665979.1 - 1.1e-25 90.4 0.0 1.1e-25 90.4 0.0 2.9 2 2 1 3 3 3 1 Nuf2 family TACC_C PF05010.14 XP_665979.1 - 0.0038 17.0 23.3 0.0038 17.0 23.3 3.5 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2379 PF09543.10 XP_665979.1 - 0.0052 17.0 0.7 0.0052 17.0 0.7 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2379) Filament PF00038.21 XP_665979.1 - 0.93 9.0 54.6 0.088 12.4 12.3 3.9 1 1 3 4 4 4 0 Intermediate filament protein DHR10 PF18595.1 XP_665979.1 - 1.4 9.0 53.0 0.77 9.8 19.4 4.2 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain GAS PF13851.6 XP_665979.1 - 2.7 7.3 59.8 0.41 10.0 14.6 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding GMC_oxred_C PF05199.13 XP_665981.1 - 3.7e-10 40.5 0.0 1.9e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 XP_665981.1 - 9.1e-09 35.1 0.1 1.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DNA_pol_E_B PF04042.16 XP_665982.1 - 7.7e-19 67.9 2.1 6.4e-18 64.9 2.1 2.1 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2691 PF10903.8 XP_665982.1 - 0.00051 19.9 0.5 0.0012 18.7 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2691) AIG2_2 PF13772.6 XP_665983.1 - 0.037 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family Peptidase_M24 PF00557.24 XP_665984.1 - 5.2e-36 124.3 0.0 6.7e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 E1-E2_ATPase PF00122.20 XP_665988.1 - 2e-26 92.6 0.1 2e-26 92.6 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 XP_665988.1 - 3.9e-12 46.4 0.0 1.8e-11 44.3 0.0 2.2 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 XP_665988.1 - 2e-10 41.3 0.0 0.016 15.5 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_665988.1 - 9.9e-05 22.4 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF3060 PF11259.8 XP_665988.1 - 1.1 9.0 5.2 0.66 9.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) eRF1_1 PF03463.15 XP_665989.1 - 2.1e-33 115.1 0.6 2.1e-33 115.1 0.6 1.8 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 XP_665989.1 - 2.6e-20 73.0 0.1 2.2e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.15 XP_665989.1 - 1.5e-13 51.2 0.1 2.8e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 S4 PF01479.25 XP_665990.1 - 1.6e-11 43.8 0.6 3.2e-11 42.7 0.6 1.5 1 0 0 1 1 1 1 S4 domain E2F_TDP PF02319.20 XP_665991.1 - 2.3e-13 50.0 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain ANAPC4_WD40 PF12894.7 XP_665992.1 - 1e-10 41.8 0.1 7.2e-05 23.0 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 XP_665992.1 - 3.3e-09 36.4 0.2 6e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 XP_665992.1 - 1.2e-05 24.7 1.1 0.00018 20.9 0.1 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 XP_665992.1 - 0.0053 17.6 0.3 0.43 11.5 0.2 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Lipocalin PF00061.23 XP_665992.1 - 0.09 13.0 0.1 0.93 9.7 0.0 2.6 3 0 0 3 3 3 0 Lipocalin / cytosolic fatty-acid binding protein family AOX PF01786.17 XP_665993.1 - 2.3e-83 279.0 0.0 2.9e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Ssl1 PF04056.14 XP_665994.1 - 1.2e-32 113.3 0.1 1.7e-32 112.8 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 XP_665994.1 - 6.7e-08 33.1 0.0 1.3e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 XP_665994.1 - 0.038 14.2 29.4 0.051 13.8 17.9 3.3 2 1 1 3 3 3 0 TFIIH C1-like domain MFS_1 PF07690.16 XP_665995.1 - 5.6e-14 51.8 23.0 1.5e-09 37.3 17.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 XP_665995.1 - 0.00042 19.3 10.8 0.24 10.2 0.1 3.3 3 0 0 3 3 3 3 Sugar (and other) transporter Kinesin PF00225.23 XP_665996.1 - 2.8e-84 282.9 9.5 2.8e-84 282.9 9.5 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 XP_665996.1 - 1.3e-16 60.9 11.4 2e-15 57.0 0.0 3.9 2 2 1 3 3 3 2 Microtubule binding Helicase_IV_N PF12462.8 XP_665998.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal EF-hand_4 PF12763.7 XP_665999.1 - 3.6e-12 46.2 2.3 7.6e-06 25.8 0.5 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 XP_665999.1 - 8.4e-07 28.1 6.5 0.033 13.7 0.6 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 XP_665999.1 - 4.9e-05 23.7 9.9 0.0016 18.9 1.5 3.7 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 XP_665999.1 - 0.0004 20.1 5.2 1.3 9.1 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 XP_665999.1 - 0.00047 19.9 0.6 1 9.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair TMF_TATA_bd PF12325.8 XP_665999.1 - 0.02 15.1 4.5 0.039 14.2 4.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding EF-hand_5 PF13202.6 XP_665999.1 - 0.034 13.7 1.9 0.29 10.7 0.1 2.6 2 0 0 2 2 2 0 EF hand DUF2087 PF09860.9 XP_665999.1 - 0.14 12.3 0.0 0.54 10.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF5063 PF16702.5 XP_665999.1 - 0.63 10.4 3.0 0.45 10.9 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) BRE1 PF08647.11 XP_665999.1 - 1.3 9.2 9.7 3.8 7.6 9.7 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase MCM PF00493.23 XP_666000.1 - 7.2e-95 316.3 0.0 8.7e-83 276.8 0.0 2.7 2 1 1 3 3 3 2 MCM P-loop domain MCM_OB PF17207.3 XP_666000.1 - 1.1e-33 115.8 0.3 2.2e-33 114.8 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 XP_666000.1 - 4.3e-28 97.6 0.1 1e-27 96.4 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 XP_666000.1 - 4.8e-06 26.1 0.0 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 XP_666000.1 - 5.9e-06 26.8 0.0 8.6e-05 23.1 0.0 2.8 1 1 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 XP_666000.1 - 2.9e-05 24.1 0.0 0.0001 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 XP_666000.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 XP_666000.1 - 0.014 15.8 0.2 1.5 9.2 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Mg_chelatase_C PF13335.6 XP_666000.1 - 0.042 14.5 0.2 1.1 10.0 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal COG2 PF06148.11 XP_666001.1 - 0.00021 21.4 2.4 0.0014 18.7 1.9 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 XP_666001.1 - 0.002 18.5 3.9 0.0069 16.8 0.4 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF3510) Helicase_RecD PF05127.14 XP_666002.1 - 0.071 13.0 0.9 0.12 12.3 0.6 1.5 1 1 0 1 1 1 0 Helicase Chromo PF00385.24 XP_666003.1 - 1.5e-10 40.8 0.5 4.6e-10 39.3 0.5 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RCC1_2 PF13540.6 XP_666003.1 - 0.34 10.8 1.4 6.4 6.7 0.1 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Plant_all_beta PF10532.9 XP_666003.1 - 8.6 6.7 8.5 31 4.9 3.1 2.9 2 0 0 2 2 2 0 Plant specific N-all beta domain RWD PF05773.22 XP_666004.1 - 1.7e-05 25.1 6.8 8.6e-05 22.8 6.8 2.2 1 1 0 1 1 1 1 RWD domain DFRP_C PF16543.5 XP_666004.1 - 8.8e-05 22.9 1.1 0.00019 21.9 1.1 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Elf1 PF05129.13 XP_666005.1 - 3.8e-26 90.9 3.9 6.9e-26 90.1 3.9 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 XP_666005.1 - 0.016 15.6 0.3 0.053 13.9 0.2 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar Rubredoxin PF00301.20 XP_666005.1 - 0.13 12.3 1.1 7.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin FdhE PF04216.12 XP_666005.1 - 0.18 11.7 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DNA_methylase PF00145.17 XP_666006.1 - 4.7e-09 36.0 1.6 6.4e-09 35.6 1.6 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase HP0268 PF18618.1 XP_666006.1 - 0.037 14.4 0.3 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 HP0268 PGA2 PF07543.12 XP_666008.1 - 0.21 11.6 11.7 0.28 11.2 0.3 3.3 3 0 0 3 3 3 0 Protein trafficking PGA2 Helicase_Sgs1 PF11408.8 XP_666008.1 - 0.37 10.9 8.8 0.4 10.8 0.3 3.9 3 0 0 3 3 3 0 Sgs1 RecQ helicase KxDL PF10241.9 XP_666009.1 - 0.0056 16.9 5.1 0.0056 16.9 5.1 4.2 4 0 0 4 4 4 2 Uncharacterized conserved protein PFK PF00365.20 XP_666009.1 - 0.009 15.4 1.4 0.025 13.9 1.4 1.7 1 0 0 1 1 1 1 Phosphofructokinase Serglycin PF04360.12 XP_666009.1 - 0.024 14.6 0.6 0.024 14.6 0.6 2.1 2 0 0 2 2 2 0 Serglycin GCD14 PF08704.10 XP_666010.1 - 3e-61 207.2 0.3 1.8e-59 201.4 0.0 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 XP_666010.1 - 2.7e-05 24.0 0.0 5.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 XP_666010.1 - 8.3e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase GCD14_N PF14801.6 XP_666010.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 XP_666010.1 - 0.00066 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 XP_666010.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.22 XP_666011.1 - 3.2e-07 30.1 0.0 6.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 XP_666011.1 - 5.5e-05 22.8 9.4 5.5e-05 22.8 9.4 4.4 4 0 0 4 4 4 2 Collagen triple helix repeat (20 copies) IMCp PF12314.8 XP_666013.1 - 8.9e-19 67.6 58.8 3.9e-18 65.5 26.8 3.6 1 1 2 3 3 3 3 Inner membrane complex protein DUF727 PF05303.12 XP_666014.1 - 0.012 15.7 0.6 0.14 12.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF727) DHHC PF01529.20 XP_666015.1 - 9.3e-20 71.1 10.4 9.3e-20 71.1 10.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cation_efflux PF01545.21 XP_666015.1 - 0.0076 16.0 2.2 0.011 15.4 2.2 1.3 1 0 0 1 1 1 1 Cation efflux family CbiX PF01903.17 XP_666015.1 - 0.062 13.6 0.1 0.098 13.0 0.1 1.3 1 0 0 1 1 1 0 CbiX UPF0542 PF15086.6 XP_666015.1 - 0.094 12.7 0.1 0.094 12.7 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Saf_2TM PF18303.1 XP_666015.1 - 0.24 11.0 3.6 0.21 11.2 2.3 1.5 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF5373 PF17343.2 XP_666015.1 - 0.31 10.9 8.9 0.59 9.9 8.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5373) Use1 PF09753.9 XP_666018.1 - 1.1 9.0 8.6 3.7 7.2 4.9 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 EF-hand_6 PF13405.6 XP_666019.1 - 6.8e-08 31.8 2.1 0.0043 16.9 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 XP_666019.1 - 3.3e-07 30.6 0.6 0.00051 20.4 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_666019.1 - 1.6e-06 27.2 8.4 0.0037 16.7 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 XP_666019.1 - 0.00081 19.2 0.3 0.65 9.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 XP_666019.1 - 0.0056 16.1 1.9 0.13 11.8 0.0 3.2 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 XP_666019.1 - 0.12 12.7 0.3 6.1 7.2 0.0 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region GBP PF02263.19 XP_666020.1 - 0.0028 17.0 3.3 0.27 10.4 0.3 3.2 2 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 XP_666020.1 - 0.91 8.9 8.9 0.041 13.3 2.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Vma12 PF11712.8 XP_666021.1 - 4.8e-09 36.4 0.0 9.4e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2856 PF11043.8 XP_666021.1 - 0.015 15.4 0.2 0.34 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2856) DUF2951 PF11166.8 XP_666021.1 - 0.36 11.1 4.9 5.2 7.4 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) PseudoU_synth_2 PF00849.22 XP_666024.1 - 1.5e-21 77.1 0.1 2.5e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 XP_666024.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain RINGv PF12906.7 XP_666025.1 - 5.4e-12 45.6 6.5 7.4e-12 45.2 6.5 1.2 1 0 0 1 1 1 1 RING-variant domain NADH-u_ox-rdase PF10785.9 XP_666025.1 - 0.098 13.4 0.3 0.16 12.7 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit zf-RING_2 PF13639.6 XP_666025.1 - 0.4 11.0 7.5 6.4 7.2 8.4 2.1 1 1 1 2 2 2 0 Ring finger domain PhoLip_ATPase_C PF16212.5 XP_666026.1 - 3e-42 145.1 24.2 3e-42 145.1 24.2 2.6 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 XP_666026.1 - 2.2e-17 62.5 3.4 2.2e-17 62.5 3.4 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 XP_666026.1 - 1.5e-11 44.1 0.2 1.2e-09 38.0 0.2 3.2 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 XP_666026.1 - 2.1e-10 40.5 0.0 8.5e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 XP_666026.1 - 2.5e-09 37.7 0.0 0.0007 19.9 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 XP_666026.1 - 1.8 8.2 9.5 0.21 11.3 4.1 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase LXG PF04740.12 XP_666028.1 - 0.0086 15.8 0.5 0.019 14.7 0.5 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily Dus PF01207.17 XP_666028.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TMPIT PF07851.13 XP_666028.1 - 0.27 10.5 0.9 0.42 9.8 0.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Glyco_hydro_129 PF11308.8 XP_666029.1 - 0.16 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 CDC45 PF02724.14 XP_666030.1 - 0.00044 18.7 17.9 0.00047 18.6 17.9 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 XP_666030.1 - 0.028 13.8 20.3 0.05 13.0 20.3 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 XP_666030.1 - 0.049 11.8 18.8 0.058 11.6 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family PT PF04886.12 XP_666030.1 - 0.12 11.9 0.5 0.19 11.3 0.5 1.2 1 0 0 1 1 1 0 PT repeat GRP PF07172.11 XP_666030.1 - 0.16 12.7 4.2 0.42 11.3 0.0 2.5 2 0 0 2 2 2 0 Glycine rich protein family Sporozoite_P67 PF05642.11 XP_666030.1 - 0.43 8.6 8.3 0.75 7.8 8.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SOBP PF15279.6 XP_666030.1 - 4.8 7.7 10.1 2.6 8.6 8.1 1.5 1 1 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 XP_666030.1 - 9.5 5.9 15.9 4.4 7.0 11.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TSP_1 PF00090.19 XP_666032.1 - 2.5e-27 94.8 30.5 9.7e-11 41.7 5.6 3.6 3 0 0 3 3 3 3 Thrombospondin type 1 domain EGF PF00008.27 XP_666032.1 - 0.00028 21.1 10.3 0.00075 19.8 7.5 3.1 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 XP_666032.1 - 0.011 16.3 6.1 0.081 13.6 3.3 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF ATP-synt_8 PF00895.20 XP_666032.1 - 0.19 12.2 0.8 0.65 10.5 0.8 1.9 1 0 0 1 1 1 0 ATP synthase protein 8 ATG_C PF09333.11 XP_666033.1 - 3.8e-07 30.4 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 XP_666033.1 - 2.3e-05 24.2 2.4 0.052 13.3 0.0 4.0 3 0 0 3 3 3 3 Vacuolar-sorting-associated 13 protein C-terminal IL22 PF14565.6 XP_666034.1 - 0.34 11.2 4.7 27 5.0 0.9 2.9 2 1 1 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor WEMBL PF05701.11 XP_666035.1 - 0.0084 14.9 2.4 0.013 14.2 2.1 1.4 1 1 0 1 1 1 1 Weak chloroplast movement under blue light TMPIT PF07851.13 XP_666035.1 - 0.038 13.3 0.8 0.051 12.8 0.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein DapH_N PF08503.10 XP_666035.1 - 0.14 12.4 0.1 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal eIF-3c_N PF05470.12 XP_666037.1 - 7.3e-119 397.8 21.1 5.8e-66 223.1 2.9 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 XP_666037.1 - 3.9e-09 36.9 1.3 1.5e-08 35.1 0.4 2.6 2 0 0 2 2 2 1 PCI domain Col_cuticle_N PF01484.17 XP_666038.1 - 0.0082 16.2 0.3 14 5.8 0.1 3.4 3 0 0 3 3 3 2 Nematode cuticle collagen N-terminal domain Peptidase_M16_C PF05193.21 XP_666042.1 - 5.9e-10 39.5 0.1 5.4e-08 33.1 0.2 2.5 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_666042.1 - 8.5e-06 25.8 0.1 5.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_666043.1 - 6.2e-09 36.1 0.1 6.2e-09 36.1 0.1 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_666043.1 - 1.9e-05 24.7 0.0 8.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PI3_PI4_kinase PF00454.27 XP_666044.1 - 2.1e-29 103.1 0.6 3.1e-22 79.6 0.8 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4217 PF13959.6 XP_666044.1 - 0.14 12.4 0.4 1.5 9.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) ZapB PF06005.12 XP_666047.1 - 0.0022 18.4 4.8 0.0022 18.4 4.8 6.6 3 2 3 6 6 6 2 Cell division protein ZapB Par3_HAL_N_term PF12053.8 XP_666047.1 - 2.6 8.3 6.2 0.37 11.0 0.1 2.7 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins Phosphodiest PF01663.22 XP_666048.1 - 0.00031 20.4 6.2 0.067 12.8 6.2 2.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase XRN_M PF17846.1 XP_666049.1 - 2e-52 178.7 8.4 7.5e-52 176.8 8.3 2.0 1 1 0 1 1 1 1 Xrn1 helical domain FCH PF00611.23 XP_666050.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Glyco_transf_92 PF01697.27 XP_666051.1 - 9.7e-22 77.9 4.5 2.2e-21 76.7 4.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 XP_666051.1 - 2.4e-05 24.8 0.0 5.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF155 PF02582.14 XP_666052.1 - 7.8e-36 123.8 2.5 1.4e-35 123.0 2.5 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1978 PF09321.10 XP_666052.1 - 0.0072 15.7 2.4 0.019 14.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1978) SpoU_methylase PF00588.19 XP_666055.1 - 2.1e-27 96.0 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family BET PF17035.5 XP_666055.1 - 0.047 13.9 2.6 5.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Alginate_lyase PF05426.12 XP_666056.1 - 0.36 10.4 1.7 0.63 9.5 0.2 2.0 2 0 0 2 2 2 0 Alginate lyase ORC5_C PF14630.6 XP_666057.1 - 9.1e-26 91.0 0.0 1.5e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus UPF0016 PF01169.19 XP_666058.1 - 4.7e-43 145.4 13.6 2.1e-22 79.2 1.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 FTR1 PF03239.14 XP_666058.1 - 3.9 6.6 10.1 0.043 13.0 0.7 1.9 2 0 0 2 2 2 0 Iron permease FTR1 family HEAT_2 PF13646.6 XP_666059.1 - 2.4e-20 72.7 0.4 5.1e-11 42.8 0.0 2.7 3 0 0 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 XP_666059.1 - 1.2e-11 44.1 0.0 0.24 12.2 0.0 5.7 5 0 0 5 5 5 3 PBS lyase HEAT-like repeat HEAT PF02985.22 XP_666059.1 - 3.8e-10 39.1 0.1 0.36 11.2 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 XP_666059.1 - 0.016 15.2 1.7 0.71 9.9 0.2 2.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 XP_666059.1 - 0.02 14.8 0.2 1.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 XP_666059.1 - 0.057 13.7 0.0 0.24 11.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 XP_666059.1 - 0.083 13.4 0.1 36 5.0 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat TPR_1 PF00515.28 XP_666060.1 - 5.7e-11 41.8 1.5 0.00023 20.8 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 XP_666060.1 - 8.2e-10 38.0 0.5 0.00031 20.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_666060.1 - 1.6e-05 24.8 4.9 0.094 13.0 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 XP_666060.1 - 0.02 15.2 0.1 2.6 8.4 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 XP_666060.1 - 0.052 14.2 0.3 1.8 9.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ECH_2 PF16113.5 XP_666060.1 - 1.4 8.3 3.9 0.49 9.8 0.2 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CDP-OH_P_transf PF01066.21 XP_666061.1 - 2.1e-13 50.8 0.1 2.1e-13 50.8 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-C2H2_7 PF15269.6 XP_666061.1 - 0.026 14.6 1.6 0.2 11.8 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger LZ3wCH PF18517.1 XP_666062.1 - 2.7e-08 33.8 0.5 2.7e-08 33.8 0.5 1.8 2 0 0 2 2 2 1 Leucine zipper with capping helix domain UPF0242 PF06785.11 XP_666062.1 - 0.085 13.0 5.2 0.095 12.8 5.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_12 PF13087.6 XP_666063.1 - 2.3e-62 210.2 0.0 7.3e-62 208.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 XP_666063.1 - 1.3e-55 189.0 0.9 5e-28 98.6 0.2 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 XP_666063.1 - 3.6e-09 36.6 0.0 3.7e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 XP_666063.1 - 5.4e-08 33.3 0.0 0.0054 17.1 0.0 3.0 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 XP_666063.1 - 4.8e-06 26.5 0.0 0.04 13.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA PF00004.29 XP_666063.1 - 0.0092 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 XP_666063.1 - 0.0095 15.7 0.0 0.035 13.9 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 XP_666063.1 - 0.017 14.7 0.7 0.83 9.1 0.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 XP_666063.1 - 0.023 13.8 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 XP_666063.1 - 0.03 14.3 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 XP_666063.1 - 0.044 13.3 0.2 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 XP_666063.1 - 0.05 12.9 0.1 0.59 9.3 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 XP_666063.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Phage-scaffold PF09306.10 XP_666063.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Rad17 PF03215.15 XP_666063.1 - 0.086 12.8 0.7 0.6 10.0 0.1 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_14 PF13173.6 XP_666063.1 - 0.11 12.6 0.2 2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 XP_666063.1 - 0.16 11.7 0.1 0.43 10.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DHHC PF01529.20 XP_666064.1 - 2.5e-29 102.1 11.9 2.5e-29 102.1 11.9 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 XP_666064.1 - 4.1e-17 62.5 0.1 7.1e-09 36.1 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_666064.1 - 8.4e-16 58.1 2.7 5.7e-07 30.0 0.1 4.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_666064.1 - 9.1e-11 41.0 0.1 0.0041 17.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 XP_666064.1 - 7.4e-07 29.3 0.2 0.15 12.5 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 XP_666064.1 - 9.3e-07 29.0 0.6 0.043 14.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 XP_666065.1 - 9.2e-48 162.9 0.1 1.9e-47 161.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666065.1 - 1e-22 80.7 0.1 1.7e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CdiI_2 PF18593.1 XP_666065.1 - 0.015 16.0 0.5 2.4 8.9 0.2 2.6 2 0 0 2 2 2 0 CdiI immunity protein Glyoxalase_2 PF12681.7 XP_666065.1 - 0.082 12.8 1.3 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Glyoxalase-like domain NatB_MDM20 PF09797.9 XP_666065.1 - 0.089 11.7 0.1 0.089 11.7 0.1 2.2 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit Methyltransf_25 PF13649.6 XP_666066.1 - 3.8e-07 30.7 0.0 1.1e-06 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666066.1 - 0.0001 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NMD3 PF04981.13 XP_666068.1 - 7.4e-78 261.4 11.4 1.4e-77 260.5 11.4 1.5 1 0 0 1 1 1 1 NMD3 family Menin PF05053.13 XP_666069.1 - 0.19 10.0 22.8 0.2 10.0 22.8 1.0 1 0 0 1 1 1 0 Menin RRM_1 PF00076.22 XP_666070.1 - 9.6e-11 41.4 0.0 2.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MARVEL PF01284.23 XP_666071.1 - 0.005 16.9 9.4 0.005 16.9 9.4 2.3 2 1 0 2 2 2 1 Membrane-associating domain Rax2 PF12768.7 XP_666071.1 - 0.039 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 XP_666071.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.1 4 0 0 4 4 4 0 Adenovirus E3 region protein CR2 Acyl_transf_3 PF01757.22 XP_666071.1 - 0.21 10.6 16.8 1.1 8.2 16.8 1.8 1 1 0 1 1 1 0 Acyltransferase family DUF202 PF02656.15 XP_666071.1 - 3.1 8.3 10.3 0.15 12.5 1.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF202) PIG-P PF08510.12 XP_666071.1 - 3.7 7.5 8.9 2.2 8.2 1.6 2.4 2 0 0 2 2 2 0 PIG-P YrhC PF14143.6 XP_666071.1 - 8.2 6.6 9.0 5.3 7.2 0.1 3.4 3 1 0 3 3 3 0 YrhC-like protein AAA PF00004.29 XP_666072.1 - 4.4e-40 137.2 0.0 9.5e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 XP_666072.1 - 4.6e-10 39.1 0.1 9.8e-10 38.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 XP_666072.1 - 2.8e-05 24.2 0.1 0.00012 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 XP_666072.1 - 3.6e-05 24.1 0.2 0.0095 16.2 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 XP_666072.1 - 9.8e-05 22.8 0.2 0.0036 17.7 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 XP_666072.1 - 0.00065 19.5 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 XP_666072.1 - 0.00094 19.3 0.0 0.0035 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 XP_666072.1 - 0.0058 16.2 0.0 0.021 14.3 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 XP_666072.1 - 0.0065 17.0 0.0 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain BLOC1_2 PF10046.9 XP_666072.1 - 0.0098 16.2 0.0 0.091 13.1 0.0 2.6 3 0 0 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF815 PF05673.13 XP_666072.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 XP_666072.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 XP_666072.1 - 0.022 14.5 0.1 0.1 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 XP_666072.1 - 0.027 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 XP_666072.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 XP_666072.1 - 0.048 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 XP_666072.1 - 0.064 12.5 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 XP_666072.1 - 0.087 12.7 0.0 11 5.9 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea zf_Rg PF17915.1 XP_666072.1 - 0.091 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Reverse gyrase zinc finger IstB_IS21 PF01695.17 XP_666072.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Myosin_head PF00063.21 XP_666073.1 - 4.4e-100 335.9 3.8 4.4e-100 335.9 3.8 2.3 2 2 0 2 2 2 1 Myosin head (motor domain) Uso1_p115_C PF04871.13 XP_666073.1 - 0.0011 19.4 6.2 0.0011 19.4 6.2 5.6 2 2 5 7 7 7 1 Uso1 / p115 like vesicle tethering protein, C terminal region IQ PF00612.27 XP_666073.1 - 0.0016 18.0 16.0 0.11 12.3 0.2 4.2 4 0 0 4 4 4 2 IQ calmodulin-binding motif Spc7 PF08317.11 XP_666073.1 - 0.052 12.4 63.0 0.018 13.9 11.9 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 XP_666073.1 - 1.3 7.8 58.7 0.6 8.9 13.3 2.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2407_C PF13373.6 XP_666073.1 - 1.3 9.1 7.7 7.1 6.8 7.7 2.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain PI3_PI4_kinase PF00454.27 XP_666074.1 - 3.1e-40 138.6 0.0 8.5e-40 137.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 XP_666074.1 - 8.3e-10 38.3 0.2 2.3e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 XP_666074.1 - 0.014 14.7 0.8 1.5 8.0 0.2 2.4 2 0 0 2 2 2 0 FAT domain Bax1-I PF01027.20 XP_666075.1 - 8.1e-37 127.1 35.9 9.2e-37 126.9 35.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 XP_666077.1 - 1.3e-06 29.0 3.9 1.2 10.1 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16_C PF12931.7 XP_666077.1 - 2.3e-05 24.2 2.6 0.001 18.8 0.4 3.4 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 XP_666077.1 - 0.00019 21.7 0.0 0.46 10.8 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 XP_666077.1 - 0.00025 21.1 0.4 0.0024 17.9 0.0 2.6 2 1 0 2 2 2 1 Prp18 domain SRA1 PF07304.11 XP_666077.1 - 0.00057 19.7 4.3 0.0007 19.4 0.0 3.0 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Phage_CII PF05269.11 XP_666077.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein TUDOR PF00567.24 XP_666078.1 - 2.5e-06 27.5 0.0 5.4e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 Tudor domain DUF1488 PF07369.11 XP_666078.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) SMN PF06003.12 XP_666078.1 - 5.4 6.2 7.6 0.27 10.4 0.2 2.0 1 1 0 2 2 2 0 Survival motor neuron protein (SMN) E3_UFM1_ligase PF09743.9 XP_666079.1 - 3.6e-42 144.9 16.0 3.6e-42 144.9 16.0 1.9 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 HTH_24 PF13412.6 XP_666079.1 - 0.0041 16.6 0.4 0.025 14.1 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FeoC PF09012.10 XP_666079.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_11 PF08279.12 XP_666079.1 - 0.051 13.5 1.4 0.18 11.8 0.2 2.5 2 0 0 2 2 2 0 HTH domain CHU_C PF13585.6 XP_666079.1 - 0.092 12.8 0.2 0.092 12.8 0.2 2.8 3 0 0 3 3 3 0 C-terminal domain of CHU protein family RNA_helicase PF00910.22 XP_666080.1 - 0.0024 18.2 0.6 0.0061 16.9 0.6 1.6 1 0 0 1 1 1 1 RNA helicase zf-CCCH_3 PF15663.5 XP_666080.1 - 0.025 14.8 1.5 0.025 14.8 1.5 2.9 2 1 1 3 3 3 0 Zinc-finger containing family CLP1_P PF16575.5 XP_666081.1 - 1.9e-29 102.8 0.0 3.3e-26 92.3 0.0 2.4 1 1 1 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 XP_666081.1 - 4.7e-19 68.4 0.0 1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CbiA PF01656.23 XP_666081.1 - 5.4e-06 26.5 0.1 1.6e-05 25.0 0.1 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 XP_666081.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 XP_666081.1 - 0.0017 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 XP_666081.1 - 0.0055 16.8 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Clp1 PF06807.14 XP_666081.1 - 0.031 14.7 0.0 0.092 13.2 0.0 1.8 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 AAA_18 PF13238.6 XP_666081.1 - 0.068 13.7 0.1 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 XP_666081.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 XP_666081.1 - 0.09 13.3 0.1 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 XP_666081.1 - 0.13 12.0 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PP2C PF00481.21 XP_666083.1 - 2e-10 40.7 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 XP_666083.1 - 2.3e-07 31.0 0.0 0.0012 18.8 0.0 2.6 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 XP_666083.1 - 0.00025 20.8 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Alpha-amylase PF00128.24 XP_666084.1 - 5.7e-07 29.4 0.2 1.3e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 XP_666084.1 - 0.00049 20.5 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 XP_666084.1 - 0.0054 16.8 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF273 PF03314.14 XP_666084.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF273 CNDH2_C PF16858.5 XP_666085.1 - 1.7e-32 113.5 2.5 1.7e-32 113.5 2.5 3.4 3 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 XP_666085.1 - 6.4e-20 71.5 5.0 2e-18 66.6 5.0 3.2 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal GvpG PF05120.12 XP_666085.1 - 0.34 11.0 5.3 2.1 8.4 0.2 3.5 4 0 0 4 4 4 0 Gas vesicle protein G Collectrin PF16959.5 XP_666086.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Renal amino acid transporter DUF2721 PF11026.8 XP_666087.1 - 0.087 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Rhomboid PF01694.22 XP_666088.1 - 0.00048 20.2 1.0 0.00049 20.1 0.2 1.5 2 0 0 2 2 2 1 Rhomboid family CAML PF14963.6 XP_666091.1 - 0.0076 16.4 2.7 0.0076 16.4 2.7 2.0 1 1 1 2 2 2 1 Calcium signal-modulating cyclophilin ligand DSPc PF00782.20 XP_666093.1 - 3e-23 82.1 0.1 1.1e-22 80.3 0.1 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 XP_666093.1 - 0.021 14.7 1.8 0.22 11.5 0.0 3.3 4 0 0 4 4 4 0 Gelsolin repeat UPF0113_N PF17833.1 XP_666093.1 - 0.038 14.6 2.5 0.28 11.7 0.0 3.4 4 0 0 4 4 4 0 UPF0113 Pre-PUA domain Peptidase_S49_N PF08496.10 XP_666093.1 - 1.3 9.1 4.2 3.9 7.5 2.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Sec62 PF03839.16 XP_666093.1 - 1.5 8.3 6.1 0.38 10.2 2.3 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 AAA_lid_11 PF18198.1 XP_666094.1 - 2.5e-31 108.7 0.0 4.7e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 XP_666094.1 - 1.8e-21 76.5 0.1 5.7e-21 74.8 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 XP_666094.1 - 2.4e-18 66.4 0.0 6.3e-18 65.0 0.0 1.7 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain POT1PC PF16686.5 XP_666094.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein ORMDL PF04061.14 XP_666095.1 - 0.0022 17.8 0.0 0.0024 17.7 0.0 1.0 1 0 0 1 1 1 1 ORMDL family BSD PF03909.17 XP_666097.1 - 3.4e-12 46.2 0.1 8.7e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 BSD domain Adaptin_N PF01602.20 XP_666098.1 - 7.9e-87 292.0 20.6 2.3e-83 280.6 15.5 2.0 2 0 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 XP_666098.1 - 0.016 15.4 0.1 0.21 11.8 0.0 3.0 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 XP_666098.1 - 0.1 12.3 0.0 5.5 6.7 0.0 3.0 2 1 1 3 3 3 0 DNA alkylation repair enzyme DUF726 PF05277.12 XP_666099.1 - 1.1e-91 307.4 2.4 1.1e-91 307.4 2.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF726) DUF900 PF05990.12 XP_666099.1 - 8.8e-05 22.1 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 XP_666099.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 XP_666099.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Gly-zipper_Omp PF13488.6 XP_666100.1 - 5.4e-06 26.3 5.5 1e-05 25.4 5.5 1.4 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 XP_666100.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1269 PF06897.12 XP_666100.1 - 0.018 15.3 0.2 0.046 14.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_OmpA PF13436.6 XP_666100.1 - 0.02 14.6 10.6 0.031 14.1 10.6 1.3 1 0 0 1 1 1 0 Glycine-zipper domain ALMS_motif PF15309.6 XP_666100.1 - 0.77 10.2 5.6 2.6 8.5 5.6 1.9 1 0 0 1 1 1 0 ALMS motif Gly-zipper_YMGG PF13441.6 XP_666100.1 - 0.79 9.5 9.5 1.4 8.7 9.5 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Utp14 PF04615.13 XP_666101.1 - 0.19 10.3 7.4 0.24 9.9 7.4 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 XP_666101.1 - 1.2 7.7 8.5 1.6 7.3 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SDA1 PF05285.12 XP_666101.1 - 1.4 8.2 6.9 2.1 7.7 6.9 1.3 1 0 0 1 1 1 0 SDA1 Rtf2 PF04641.12 XP_666102.1 - 1.6e-06 27.7 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Myb_DNA-bind_7 PF15963.5 XP_666103.1 - 1.7e-19 69.5 6.0 4.5e-19 68.1 6.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 XP_666103.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Thioredoxin_7 PF13899.6 XP_666105.1 - 6.8e-10 39.0 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 XP_666105.1 - 4e-07 29.7 0.0 1.1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain Sugar_tr PF00083.24 XP_666106.1 - 1.5e-32 113.1 8.4 1.8e-32 112.8 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 XP_666106.1 - 1.3e-09 37.5 16.5 3.5e-09 36.1 17.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 XP_666106.1 - 7.9e-05 21.7 4.2 7.9e-05 21.7 4.2 1.4 2 0 0 2 2 2 1 MFS_1 like family DCP2 PF05026.13 XP_666107.1 - 2.5e-19 69.4 2.6 5.8e-19 68.2 2.6 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 XP_666107.1 - 9.7e-11 41.8 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Bromodomain PF00439.25 XP_666108.1 - 5.3e-12 45.6 0.4 2.5e-11 43.5 0.4 2.3 1 0 0 1 1 1 1 Bromodomain Thioredoxin PF00085.20 XP_666110.1 - 6.6e-24 83.9 1.3 1e-15 57.6 0.3 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 XP_666110.1 - 3.1e-15 56.6 10.0 5.3e-10 39.5 0.1 4.4 2 1 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 XP_666110.1 - 1.1e-06 28.2 3.0 0.00023 20.6 0.7 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 XP_666110.1 - 1.2e-06 28.4 0.2 0.0034 17.3 0.1 2.8 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 XP_666110.1 - 4.5e-06 27.1 2.1 0.0047 17.4 0.3 3.8 3 1 0 3 3 3 1 Thioredoxin-like domain DUF836 PF05768.14 XP_666110.1 - 1.2e-05 25.6 1.1 0.042 14.3 0.6 2.7 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_5 PF13743.6 XP_666110.1 - 0.0012 18.6 0.1 3.2 7.4 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.6 XP_666110.1 - 0.034 14.0 0.1 0.13 12.0 0.0 2.0 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 XP_666110.1 - 0.068 12.9 0.6 1.1 9.0 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin SET PF00856.28 XP_666111.1 - 6.4e-19 69.0 0.2 1.3e-18 67.9 0.2 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 XP_666111.1 - 0.0032 17.5 13.6 0.0032 17.5 13.6 3.5 3 1 0 3 3 3 1 MYND finger DUF1073 PF06381.11 XP_666111.1 - 0.012 14.5 0.4 0.021 13.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) Minor_capsid_3 PF12691.7 XP_666111.1 - 0.62 10.4 5.1 0.37 11.2 0.8 2.4 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage Peptidase_A22B PF04258.13 XP_666112.1 - 4.7e-76 256.0 14.9 7.2e-76 255.4 14.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase Pex24p PF06398.11 XP_666112.1 - 0.28 10.1 0.0 0.28 10.1 0.0 2.5 2 1 1 3 3 3 0 Integral peroxisomal membrane peroxin Thioredoxin PF00085.20 XP_666113.1 - 2.6e-26 91.6 0.8 8.2e-26 90.0 0.8 1.9 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 XP_666113.1 - 2.1e-06 27.3 4.4 0.0022 17.4 0.3 2.8 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 XP_666113.1 - 0.0013 19.2 0.3 0.0043 17.5 0.3 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 XP_666113.1 - 0.0013 18.7 0.2 0.003 17.4 0.2 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.6 XP_666113.1 - 0.0013 18.7 14.1 0.016 15.1 3.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 XP_666113.1 - 0.0032 17.8 0.6 0.015 15.6 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin-like RRM_3 PF08777.11 XP_666114.1 - 0.13 12.3 0.9 0.2 11.7 0.9 1.2 1 0 0 1 1 1 0 RNA binding motif DUF410 PF04190.13 XP_666115.1 - 8e-34 117.6 5.8 9.3e-34 117.4 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF4831 PF16115.5 XP_666116.1 - 0.22 10.5 6.3 0.019 14.0 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) Adaptin_binding PF10199.9 XP_666116.1 - 0.45 11.1 4.1 0.32 11.6 1.2 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Arf PF00025.21 XP_666117.1 - 3.2e-16 59.3 0.0 1.8e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 XP_666117.1 - 0.0001 21.8 0.5 0.0079 15.6 0.5 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 XP_666117.1 - 0.0046 16.6 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 2 Ras family G-alpha PF00503.20 XP_666117.1 - 0.0049 16.1 0.2 0.0071 15.5 0.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit T2SSE PF00437.20 XP_666117.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_32 PF13654.6 XP_666117.1 - 0.076 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain zinc_ribbon_6 PF14599.6 XP_666118.1 - 6.5e-19 67.7 1.4 6.5e-19 67.7 1.4 4.2 3 2 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 XP_666118.1 - 3.2e-16 59.6 22.1 3.2e-16 59.6 22.1 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 XP_666118.1 - 7.6e-07 29.4 2.4 7.6e-07 29.4 2.4 5.9 2 1 4 6 6 6 1 Ring finger domain zf-RING_UBOX PF13445.6 XP_666118.1 - 1.9e-06 27.8 1.1 1.9e-06 27.8 1.1 5.8 7 2 1 8 8 8 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 XP_666118.1 - 0.019 15.1 2.3 0.019 15.1 2.3 6.1 5 3 1 6 6 6 0 zinc finger of C3HC4-type, RING TFIID_NTD2 PF04494.15 XP_666119.1 - 1.2e-18 67.6 2.0 1.2e-18 67.6 2.0 2.5 1 1 1 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 XP_666119.1 - 1.6e-15 57.2 21.0 4.3e-06 27.4 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_666119.1 - 6.3e-06 26.4 1.8 1.6 9.1 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 XP_666119.1 - 0.023 14.6 0.8 0.023 14.6 0.8 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS HTH_46 PF15977.5 XP_666119.1 - 0.075 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding DUF1298 PF06974.13 XP_666121.1 - 6.4e-24 84.6 0.0 8.6e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Helicase_C PF00271.31 XP_666122.1 - 0.00031 21.1 7.3 0.1 13.0 0.1 4.2 1 1 2 3 3 3 2 Helicase conserved C-terminal domain Sec20 PF03908.13 XP_666122.1 - 0.5 10.3 5.4 0.42 10.6 0.3 3.1 2 0 0 2 2 2 0 Sec20 KH_1 PF00013.29 XP_666123.1 - 9.4e-15 54.2 4.8 1.8e-10 40.5 1.8 2.7 3 0 0 3 3 3 2 KH domain Beta-Casp PF10996.8 XP_666125.1 - 6.7e-18 65.0 0.0 1.5e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 XP_666125.1 - 2.3e-17 62.6 0.1 3e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF73-100_C PF11718.8 XP_666125.1 - 4e-05 23.3 0.3 7.8e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term HP1451_C PF18472.1 XP_666125.1 - 0.012 15.5 0.5 0.046 13.7 0.5 2.0 1 0 0 1 1 1 0 HP1451 C-terminal domain DisA-linker PF10635.9 XP_666125.1 - 0.47 10.2 3.8 0.21 11.4 0.7 2.0 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region DnaJ PF00226.31 XP_666126.1 - 7.3e-16 58.0 0.9 7.3e-16 58.0 0.9 2.6 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 XP_666126.1 - 0.0044 16.9 0.1 0.045 13.7 0.0 2.6 2 1 1 3 3 3 1 A repeated domain in UCH-protein DUF2208 PF09973.9 XP_666126.1 - 0.69 9.5 3.0 1.2 8.7 3.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Ribosomal_L5e PF17144.4 XP_666127.1 - 2.9e-83 277.7 0.1 2.9e-83 277.7 0.1 2.1 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 XP_666127.1 - 8.7e-31 106.7 8.8 8.7e-31 106.7 8.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4208 PF13907.6 XP_666127.1 - 0.044 14.2 0.4 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Ribosomal_L7Ae PF01248.26 XP_666128.1 - 1.2e-20 73.0 0.8 2.4e-20 72.1 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DSHCT PF08148.12 XP_666131.1 - 1.1e-34 119.4 0.1 3e-34 118.0 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 XP_666131.1 - 1.6e-19 70.3 0.1 8.9e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_666131.1 - 3.1e-07 30.7 0.1 3.1e-07 30.7 0.1 4.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AP2 PF00847.20 XP_666133.1 - 7e-15 55.0 3.4 1.4e-14 54.0 3.4 1.5 1 0 0 1 1 1 1 AP2 domain ParA PF10609.9 XP_666135.1 - 1.6e-84 283.2 0.5 2e-84 282.9 0.5 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 XP_666135.1 - 4.4e-11 42.9 0.0 7.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 XP_666135.1 - 2.8e-09 37.1 0.0 7.5e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 XP_666135.1 - 2.4e-06 27.0 2.4 0.00012 21.4 0.1 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 XP_666135.1 - 2.1e-05 23.9 0.0 5.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ NB-ARC PF00931.22 XP_666135.1 - 0.0015 17.8 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 XP_666135.1 - 0.0035 17.3 0.6 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_26 PF13500.6 XP_666135.1 - 0.015 15.1 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 XP_666135.1 - 0.057 13.3 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 XP_666135.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 XP_666135.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNase_H2_suC PF08615.11 XP_666136.1 - 5.1e-08 33.2 1.1 2.2e-07 31.1 1.0 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Methyltransf_7 PF03492.15 XP_666136.1 - 0.0056 15.9 0.4 0.006 15.8 0.4 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase PTH2 PF01981.16 XP_666138.1 - 6e-34 116.8 0.0 6.6e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AsnC_trans_reg PF01037.21 XP_666138.1 - 0.0015 18.4 0.0 0.0043 17.0 0.0 1.7 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain TPR_14 PF13428.6 XP_666138.1 - 0.098 13.5 0.0 0.46 11.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Condensin2nSMC PF12422.8 XP_666139.1 - 1.9e-39 135.2 0.6 1.9e-39 135.2 0.6 2.9 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 XP_666139.1 - 1.2e-08 34.5 0.6 0.013 15.7 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 XP_666139.1 - 0.011 16.2 0.0 1.5 9.3 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats HSCB_C PF07743.13 XP_666139.1 - 0.085 13.4 0.3 3.5 8.2 0.0 2.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Cnd1 PF12717.7 XP_666139.1 - 3.1 7.8 11.7 2 8.4 0.1 4.1 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 ERO1 PF04137.15 XP_666140.1 - 2.2e-18 66.6 5.3 1.5e-14 54.0 1.3 2.9 1 1 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DASH_Dam1 PF08653.10 XP_666141.1 - 0.098 12.5 1.0 0.27 11.0 1.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 Dapper PF15268.6 XP_666141.1 - 6.1 5.6 28.8 7.7 5.2 28.8 1.1 1 0 0 1 1 1 0 Dapper Guanylate_cyc PF00211.20 XP_666142.1 - 5.8e-71 237.9 6.3 3.4e-35 121.3 1.7 3.7 3 1 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 XP_666142.1 - 3.7e-26 92.4 32.1 3.7e-26 92.4 32.1 4.0 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal DUF1053 PF06327.14 XP_666142.1 - 5.7 7.5 8.1 6.5 7.4 2.2 3.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) CBFD_NFYB_HMF PF00808.23 XP_666143.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 XP_666143.1 - 5.4e-09 36.5 0.1 1.1e-08 35.5 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 XP_666143.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID_20kDa PF03847.13 XP_666143.1 - 0.027 15.0 0.1 0.081 13.4 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A ESSS PF10183.9 XP_666143.1 - 0.13 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UCR_14kD PF02271.16 XP_666144.1 - 0.051 13.5 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Ras PF00071.22 XP_666144.1 - 0.096 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Ras family Med24_N PF11277.8 XP_666145.1 - 0.0015 16.7 0.1 0.0017 16.5 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal EF-hand_1 PF00036.32 XP_666145.1 - 0.095 12.3 0.2 12 5.7 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 XP_666145.1 - 0.14 12.0 0.3 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair TBCC PF07986.12 XP_666146.1 - 8e-16 57.9 6.3 1.6e-15 56.9 6.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 XP_666146.1 - 2.4e-05 24.0 2.5 6.2e-05 22.7 1.7 2.1 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal DUF4293 PF14126.6 XP_666147.1 - 2.3 8.4 13.1 21 5.3 13.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Ninjurin PF04923.12 XP_666147.1 - 2.6 8.0 8.1 7.7 6.5 0.8 3.0 3 0 0 3 3 3 0 Ninjurin TPR_2 PF07719.17 XP_666148.1 - 3.9e-15 54.7 0.1 0.0068 16.4 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 XP_666148.1 - 9.8e-13 47.3 1.8 0.0035 17.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 XP_666148.1 - 1.3e-09 38.1 0.0 0.079 13.6 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 XP_666148.1 - 1.2e-06 28.6 0.0 0.59 10.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_666148.1 - 5.8e-06 26.1 0.8 1.1 9.6 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 XP_666148.1 - 0.00072 20.2 0.0 0.051 14.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 XP_666148.1 - 0.0026 17.7 0.4 12 6.2 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 XP_666148.1 - 0.0091 15.7 0.1 2.2 8.0 0.0 3.2 4 0 0 4 4 4 1 TPR repeat TPR_3 PF07720.12 XP_666148.1 - 0.054 13.5 6.1 23 5.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 XP_666148.1 - 0.081 12.8 2.7 3.5 7.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 XP_666150.1 - 3.3e-23 82.4 0.0 2.4e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S49_N PF08496.10 XP_666150.1 - 0.068 13.2 3.2 0.14 12.2 3.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CHD5 PF04420.14 XP_666150.1 - 0.23 11.3 3.2 0.54 10.1 3.2 1.6 1 0 0 1 1 1 0 CHD5-like protein RST PF12174.8 XP_666150.1 - 0.29 11.1 3.1 0.81 9.7 0.0 2.9 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Erf4 PF10256.9 XP_666150.1 - 8.3 6.6 9.7 0.7 10.0 2.5 2.7 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family ABC1 PF03109.16 XP_666151.1 - 4.9e-29 100.9 1.2 7.4e-29 100.3 0.7 1.6 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 XP_666151.1 - 0.00019 20.9 3.7 0.001 18.5 3.7 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF5130 PF17174.4 XP_666152.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) DUF3150 PF11348.8 XP_666152.1 - 0.026 13.8 0.2 0.04 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Prok-RING_4 PF14447.6 XP_666153.1 - 0.027 14.3 9.3 0.11 12.4 9.3 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 XP_666153.1 - 0.12 12.5 7.1 0.43 10.8 7.1 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 XP_666153.1 - 0.4 11.1 16.6 0.17 12.3 12.2 2.8 2 0 0 2 2 2 0 Ring finger domain zf-MIZ PF02891.20 XP_666153.1 - 0.42 10.4 11.7 1.2 9.0 11.7 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 XP_666153.1 - 9.5 6.3 22.6 0.15 12.0 13.3 2.9 3 0 0 3 3 3 0 zinc-RING finger domain ABC_tran PF00005.27 XP_666154.1 - 1.6e-36 125.8 0.0 7.4e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 XP_666154.1 - 2.5e-14 52.8 2.9 6.2e-14 51.5 2.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 XP_666154.1 - 2.2e-11 44.1 3.8 0.0024 17.7 0.0 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 XP_666154.1 - 7.6e-11 41.9 4.6 0.0014 18.1 0.1 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 XP_666154.1 - 2.3e-07 30.9 0.6 0.012 15.3 0.1 3.1 2 1 0 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 XP_666154.1 - 3.1e-07 30.5 0.0 0.031 14.2 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain Fer4 PF00037.27 XP_666154.1 - 2e-06 27.4 3.4 2e-06 27.4 3.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 XP_666154.1 - 3.5e-05 24.3 4.9 0.00018 22.0 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 XP_666154.1 - 3.8e-05 23.6 0.1 0.28 11.1 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase Fer4_6 PF12837.7 XP_666154.1 - 4e-05 23.5 2.9 4e-05 23.5 2.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 XP_666154.1 - 0.00037 20.2 0.3 0.59 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 XP_666154.1 - 0.0004 21.0 3.8 0.019 15.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 XP_666154.1 - 0.00098 18.4 0.0 0.63 9.1 0.3 2.9 1 1 0 2 2 2 1 G-protein alpha subunit RNA_helicase PF00910.22 XP_666154.1 - 0.0011 19.4 0.1 1.8 9.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 XP_666154.1 - 0.0011 18.9 0.3 0.37 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 XP_666154.1 - 0.0013 19.2 1.7 0.35 11.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA PF00004.29 XP_666154.1 - 0.0014 19.1 0.2 0.51 10.8 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 XP_666154.1 - 0.0015 18.2 0.2 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 XP_666154.1 - 0.0021 17.4 0.0 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Fer4_16 PF13484.6 XP_666154.1 - 0.0033 18.3 4.7 0.0047 17.8 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain SbcCD_C PF13558.6 XP_666154.1 - 0.0038 17.4 0.0 0.62 10.3 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.6 XP_666154.1 - 0.0065 16.6 11.2 0.013 15.6 11.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 XP_666154.1 - 0.0072 16.4 1.8 0.0072 16.4 1.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 XP_666154.1 - 0.0075 16.4 0.0 0.74 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 XP_666154.1 - 0.008 16.3 1.9 0.008 16.3 1.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_16 PF13191.6 XP_666154.1 - 0.012 16.0 0.0 8.1 6.8 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 XP_666154.1 - 0.015 15.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 XP_666154.1 - 0.018 15.1 0.5 2.1 8.4 0.0 3.1 2 1 1 3 3 3 0 AAA domain VirE PF05272.11 XP_666154.1 - 0.019 14.7 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_28 PF13521.6 XP_666154.1 - 0.021 15.1 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 XP_666154.1 - 0.022 13.9 0.5 12 5.0 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Fer4_21 PF14697.6 XP_666154.1 - 0.027 14.6 12.8 0.069 13.3 12.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_5 PF07728.14 XP_666154.1 - 0.029 14.4 0.3 14 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 XP_666154.1 - 0.038 14.0 0.1 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 XP_666154.1 - 0.048 13.9 0.0 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 XP_666154.1 - 0.078 13.4 0.2 0.078 13.4 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain MeaB PF03308.16 XP_666154.1 - 0.078 11.9 0.4 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 XP_666154.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 XP_666154.1 - 0.088 12.9 0.0 20 5.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 XP_666154.1 - 0.12 12.1 0.6 1.6 8.5 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.7 XP_666154.1 - 0.36 11.4 16.3 0.55 10.9 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FeoB_N PF02421.18 XP_666154.1 - 0.9 9.0 3.0 8.7 5.9 0.1 3.5 4 1 1 5 5 5 0 Ferrous iron transport protein B NTPase_1 PF03266.15 XP_666154.1 - 3.1 7.7 5.1 49 3.8 0.0 3.9 6 0 0 6 6 4 0 NTPase Fer4_17 PF13534.6 XP_666154.1 - 5.6 7.6 11.6 0.063 13.8 1.5 2.4 1 1 2 3 3 2 0 4Fe-4S dicluster domain PNTB PF02233.16 XP_666155.1 - 2.9e-113 379.2 7.3 1.5e-112 376.9 0.7 2.2 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 XP_666155.1 - 6.2e-55 185.8 0.2 1.8e-53 181.1 0.0 3.0 3 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 XP_666155.1 - 1.9e-27 95.6 4.8 6.4e-27 93.8 4.8 2.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_N PF05222.15 XP_666155.1 - 2.8e-18 66.5 0.0 5.8e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 XP_666155.1 - 6.8e-08 32.1 2.1 8.7e-05 22.0 0.1 3.7 2 1 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 XP_666155.1 - 0.00068 19.4 0.6 0.027 14.2 0.1 3.7 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.20 XP_666155.1 - 0.0033 17.5 2.8 0.69 10.0 0.6 4.1 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 XP_666155.1 - 0.0045 16.3 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 XP_666155.1 - 0.013 14.6 0.5 0.031 13.4 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 XP_666155.1 - 0.03 14.7 1.0 0.33 11.4 0.1 3.0 4 0 0 4 4 4 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 XP_666155.1 - 0.034 13.2 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF5056 PF16479.5 XP_666155.1 - 0.072 13.3 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) ADH_zinc_N PF00107.26 XP_666155.1 - 0.1 12.6 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 XP_666155.1 - 0.1 13.2 0.2 0.93 10.1 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAGK_acc PF00609.19 XP_666156.1 - 5.3e-39 134.1 0.3 1.3e-14 54.8 0.0 3.3 3 0 0 3 3 3 3 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 XP_666156.1 - 1.2e-15 57.2 0.0 2.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RNA_pol_Rpb1_5 PF04998.17 XP_666157.1 - 3.1e-101 338.3 0.3 6.3e-101 337.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 XP_666157.1 - 6e-100 334.6 0.2 1.3e-99 333.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 XP_666157.1 - 7.8e-75 250.7 0.0 1.6e-74 249.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 XP_666157.1 - 4.3e-55 186.5 0.1 8.1e-55 185.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 XP_666157.1 - 8.3e-45 152.5 0.3 2.9e-44 150.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 XP_666157.1 - 2.9e-44 150.4 3.7 6.6e-44 149.2 3.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 XP_666157.1 - 2.5e-37 127.1 0.1 1e-36 125.1 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 XP_666157.1 - 1.4e-21 75.7 319.7 0.0027 18.0 11.4 21.5 11 4 12 25 25 25 19 RNA polymerase Rpb1 C-terminal repeat PTRF_SDPR PF15237.6 XP_666157.1 - 0.054 13.1 0.6 11 5.6 0.7 2.6 2 0 0 2 2 2 0 PTRF/SDPR family Metallophos PF00149.28 XP_666159.1 - 3.7e-12 47.2 0.0 7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kinesin PF00225.23 XP_666160.1 - 8.1e-110 366.9 2.6 8.1e-110 366.9 2.6 2.8 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 XP_666160.1 - 1.4e-24 86.7 0.2 1.4e-24 86.7 0.2 3.2 2 0 0 2 2 2 1 Microtubule binding UDPGT PF00201.18 XP_666160.1 - 0.0013 17.6 0.3 0.0013 17.6 0.3 2.1 3 0 0 3 3 3 1 UDP-glucoronosyl and UDP-glucosyl transferase ResIII PF04851.15 XP_666160.1 - 0.24 11.4 0.0 0.24 11.4 0.0 4.0 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit VIT_2 PF13757.6 XP_666160.1 - 0.31 11.0 2.5 0.33 10.9 0.6 2.0 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain AAA_22 PF13401.6 XP_666160.1 - 0.39 11.0 0.0 0.39 11.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain VASP_tetra PF08776.11 XP_666160.1 - 0.72 9.5 4.4 3.6 7.2 4.4 2.2 1 0 0 1 1 1 0 VASP tetramerisation domain RabGAP-TBC PF00566.18 XP_666161.1 - 4.7e-52 176.8 6.3 4.7e-52 176.8 6.3 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain LisH PF08513.11 XP_666161.1 - 0.13 12.2 0.2 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 LisH UQ_con PF00179.26 XP_666164.1 - 1.6e-38 131.5 0.1 2.4e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 XP_666164.1 - 9e-06 25.5 0.1 2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 XP_666164.1 - 1e-05 25.3 0.0 3.1e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B UBA_3 PF09288.10 XP_666164.1 - 0.003 17.4 0.7 0.011 15.5 0.7 1.9 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.22 XP_666164.1 - 0.005 17.1 0.7 0.0083 16.4 0.5 1.6 1 1 0 1 1 1 1 RWD domain UBA_4 PF14555.6 XP_666164.1 - 0.013 15.3 0.8 0.034 14.0 0.8 1.7 1 1 0 1 1 1 0 UBA-like domain E3_UbLigase_EDD PF11547.8 XP_666164.1 - 0.05 13.3 0.2 0.08 12.7 0.2 1.3 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD FeoA PF04023.14 XP_666164.1 - 0.17 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 FeoA domain DUF3879 PF12995.7 XP_666165.1 - 0.02 14.6 0.3 0.022 14.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) DUF2115 PF09888.9 XP_666166.1 - 0.92 10.0 6.4 0.23 12.0 0.5 2.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) ABC_membrane PF00664.23 XP_666167.1 - 1.5e-30 106.8 17.8 2.2e-30 106.3 17.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 XP_666167.1 - 2.8e-30 105.6 0.1 1e-29 103.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 XP_666167.1 - 4.3e-05 23.0 0.0 0.00016 21.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 XP_666167.1 - 0.024 14.4 0.4 0.63 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 XP_666167.1 - 0.041 13.1 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 XP_666167.1 - 0.23 11.6 0.1 0.45 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF2439 PF10382.9 XP_666168.1 - 2.3e-12 47.1 1.1 4e-12 46.3 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) EF-hand_6 PF13405.6 XP_666169.1 - 1.1e-16 59.2 0.6 0.00022 20.9 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 XP_666169.1 - 1.2e-16 60.9 0.2 4.4e-09 36.7 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_666169.1 - 3.5e-16 57.5 2.7 7.3e-06 25.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 XP_666169.1 - 3.6e-12 45.2 0.9 0.0021 17.4 0.0 3.3 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 XP_666169.1 - 7.8e-09 35.9 0.0 2.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 XP_666169.1 - 3.4e-05 23.6 2.2 0.0046 16.8 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain pair Dockerin_1 PF00404.18 XP_666169.1 - 0.0068 16.6 0.3 0.87 9.8 0.3 3.0 2 1 1 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 XP_666169.1 - 0.021 14.7 0.3 0.7 9.8 0.0 2.5 1 1 1 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 XP_666169.1 - 0.072 13.0 0.8 3.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DHHC PF01529.20 XP_666170.1 - 7.6e-35 119.9 27.7 9.2e-35 119.7 12.3 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF973 PF06157.11 XP_666170.1 - 0.91 8.5 9.4 0.085 11.9 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Plk4_PB1 PF18190.1 XP_666171.1 - 0.016 15.4 0.7 0.038 14.1 0.2 2.0 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Thioredoxin PF00085.20 XP_666173.1 - 1.5e-37 127.7 0.0 3.4e-19 68.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 XP_666173.1 - 2.5e-09 37.3 10.0 1.6e-07 31.5 1.3 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 XP_666173.1 - 6.8e-06 26.5 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 XP_666173.1 - 1.5e-05 24.9 0.0 0.025 14.5 0.0 2.9 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 XP_666173.1 - 0.00013 21.7 0.0 0.029 14.1 0.0 2.9 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 XP_666173.1 - 0.00036 20.6 0.0 0.093 12.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 XP_666173.1 - 0.00074 19.0 0.1 0.21 10.9 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 XP_666173.1 - 0.00097 19.4 6.5 0.074 13.4 0.0 4.7 5 1 0 5 5 5 1 Thioredoxin-like Glutaredoxin PF00462.24 XP_666173.1 - 0.094 12.9 2.4 2.6 8.4 0.5 2.8 2 1 0 2 2 2 0 Glutaredoxin DUF771 PF05595.11 XP_666174.1 - 2 8.4 7.2 20 5.2 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF771) LRR_6 PF13516.6 XP_666174.1 - 9.3 6.6 6.7 5.2 7.4 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich repeat SPC25 PF06703.11 XP_666175.1 - 2.6e-05 24.1 1.4 0.00015 21.6 1.4 2.0 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1011 PF06237.12 XP_666175.1 - 0.15 12.4 0.2 0.22 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Jagunal PF07086.12 XP_666177.1 - 0.72 9.9 6.7 0.27 11.3 0.2 2.5 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis zf-LYAR PF08790.11 XP_666179.1 - 2.2e-13 49.8 7.2 2.2e-13 49.8 7.2 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger T4_baseplate PF12322.8 XP_666179.1 - 0.00036 20.0 4.6 0.00049 19.6 4.6 1.2 1 0 0 1 1 1 1 T4 bacteriophage base plate protein Cullin_Nedd8 PF10557.9 XP_666179.1 - 0.034 14.2 0.2 0.061 13.4 0.2 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain zf_UBZ PF18439.1 XP_666179.1 - 0.034 13.7 1.5 5.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 XP_666179.1 - 9.8 5.9 7.9 3.3 7.4 1.1 2.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain NPR2 PF06218.11 XP_666180.1 - 3.9e-35 121.5 9.8 3.4e-33 115.1 5.9 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 CorA PF01544.18 XP_666181.1 - 7.1e-05 22.3 2.0 0.00019 20.9 0.1 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein MutS_III PF05192.18 XP_666181.1 - 0.14 12.4 0.7 0.39 10.9 0.0 2.0 2 1 0 2 2 2 0 MutS domain III TruD PF01142.18 XP_666182.1 - 2.2e-55 188.2 3.6 5.8e-52 176.9 0.2 3.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF3967 PF13152.6 XP_666182.1 - 0.17 11.7 1.6 0.34 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) DUF1564 PF07600.11 XP_666182.1 - 0.42 10.3 8.9 0.15 11.8 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) PCI PF01399.27 XP_666183.1 - 2e-11 44.3 1.1 3.5e-11 43.5 1.1 1.3 1 0 0 1 1 1 1 PCI domain DUF4192 PF13830.6 XP_666184.1 - 0.21 11.6 4.0 0.4 10.7 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 XP_666184.1 - 7.1 5.3 8.0 12 4.5 8.0 1.3 1 0 0 1 1 1 0 Presenilin VID27_PH PF17747.1 XP_666185.1 - 0.062 13.6 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 VID27 PH-like domain Cnd2 PF05786.14 XP_666186.1 - 5.9e-13 48.4 16.1 1.4e-12 47.2 16.1 1.6 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 XP_666186.1 - 0.0024 18.1 0.5 0.0024 18.1 0.5 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal WYL_3 PF18488.1 XP_666186.1 - 0.084 13.2 1.5 0.89 10.0 0.2 2.7 2 1 0 2 2 2 0 WYL domain TetR_C_2 PF08361.11 XP_666186.1 - 0.14 12.3 0.6 0.75 9.9 0.0 2.4 3 0 0 3 3 3 0 MAATS-type transcriptional repressor, C-terminal region Actin PF00022.19 XP_666187.1 - 9.7e-144 478.9 0.0 4e-143 476.9 0.0 1.7 1 1 0 1 1 1 1 Actin Histone PF00125.24 XP_666188.1 - 3.2e-16 59.9 0.9 3.9e-16 59.6 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 XP_666188.1 - 3.2e-06 27.3 0.7 6.2e-06 26.4 0.7 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1804 PF08822.11 XP_666188.1 - 0.0021 18.0 0.6 0.0026 17.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) TFIID_20kDa PF03847.13 XP_666188.1 - 0.0045 17.5 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Pkinase PF00069.25 XP_666189.1 - 1.4e-15 57.4 0.0 8.9e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666189.1 - 2.4e-11 43.4 0.0 1.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 XP_666189.1 - 0.027 13.8 0.0 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like SAM_2 PF07647.17 XP_666190.1 - 0.0045 17.1 0.1 0.0098 16.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 XP_666190.1 - 0.022 15.2 0.1 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) USP7_ICP0_bdg PF12436.8 XP_666190.1 - 0.047 13.0 1.2 0.11 11.8 0.2 1.9 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 cEGF PF12662.7 XP_666191.1 - 2.8e-06 27.1 179.8 0.24 11.3 0.3 32.2 35 0 0 35 35 35 24 Complement Clr-like EGF-like APG6_N PF17675.1 XP_666192.1 - 0.0032 18.0 22.7 0.0032 18.0 22.7 4.3 2 1 2 4 4 4 2 Apg6 coiled-coil region ATG16 PF08614.11 XP_666192.1 - 3 8.0 53.1 0.54 10.4 7.7 4.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 XP_666192.1 - 10 5.4 63.6 0.4 10.0 15.9 4.8 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding SDA1 PF05285.12 XP_666193.1 - 1.1 8.6 22.7 0.013 15.0 12.2 2.1 2 0 0 2 2 2 0 SDA1 Inos-1-P_synth PF01658.17 XP_666194.1 - 6.7 7.0 9.1 0.33 11.2 0.3 2.7 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase WD40 PF00400.32 XP_666195.1 - 3.3e-16 59.4 12.6 0.00023 21.9 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_666195.1 - 4.8e-08 33.2 0.3 0.83 10.0 0.0 5.1 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 XP_666195.1 - 2.1e-05 23.7 0.2 0.53 9.1 0.0 3.9 4 0 0 4 4 4 3 Partner and localizer of BRCA2 WD40 domain DUF3945 PF13101.6 XP_666195.1 - 0.57 10.0 2.4 10 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3945) PMM PF03332.13 XP_666196.1 - 4.7e-26 91.9 0.1 5.2e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase PMM PF03332.13 XP_666197.1 - 5.7e-07 29.5 0.1 6.4e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase PF00702.26 XP_666197.1 - 0.0012 19.2 0.2 0.084 13.2 0.2 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 XP_666197.1 - 0.0059 16.4 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 XP_666197.1 - 0.023 14.8 2.7 0.47 10.5 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Endopep_inhib PF16800.5 XP_666197.1 - 0.1 12.5 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor MCM PF00493.23 XP_666198.1 - 3.5e-100 333.7 0.0 5.8e-100 333.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 XP_666198.1 - 2.8e-27 95.1 2.1 5.4e-27 94.1 2.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 XP_666198.1 - 3.3e-18 65.9 0.8 7.7e-18 64.7 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 XP_666198.1 - 1.7e-13 51.1 1.3 7.7e-13 48.9 1.3 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 XP_666198.1 - 4.2e-09 36.1 0.2 9.1e-06 25.2 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_666198.1 - 6.4e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 XP_666198.1 - 2.6e-05 24.3 0.0 0.00012 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 XP_666198.1 - 0.0048 17.3 0.3 0.066 13.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 XP_666198.1 - 0.042 13.5 0.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 XP_666198.1 - 0.056 13.3 1.2 42 4.0 0.0 3.4 2 1 1 3 3 3 0 NTPase PBP1_TM PF14812.6 XP_666198.1 - 0.92 9.9 10.5 0.11 12.9 3.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3130 PF11328.8 XP_666200.1 - 1.3 9.3 4.6 1.7 8.9 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Ribosomal_L15e PF00827.17 XP_666201.1 - 2.6e-87 291.5 7.1 3e-87 291.3 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 eIF-3_zeta PF05091.12 XP_666202.1 - 2.5e-152 508.5 0.7 2.9e-152 508.3 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 XP_666202.1 - 0.01 15.4 0.7 0.014 14.9 0.0 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus His_binding PF02098.16 XP_666203.1 - 0.081 13.0 0.8 0.081 13.0 0.8 1.8 2 0 0 2 2 2 0 Tick histamine binding protein V-ATPase_G PF03179.15 XP_666204.1 - 2.4e-19 69.8 6.9 2.8e-19 69.6 6.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit MAT1 PF06391.13 XP_666204.1 - 0.0046 16.8 2.8 0.0064 16.3 2.8 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DcrB PF08786.11 XP_666204.1 - 0.0074 16.4 0.1 0.0097 16.0 0.1 1.3 1 1 0 1 1 1 1 DcrB ATP-synt_B PF00430.18 XP_666204.1 - 0.5 10.4 8.9 0.58 10.3 6.1 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Exo_endo_phos PF03372.23 XP_666206.1 - 4.5e-07 29.6 0.0 4.8e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_3_hydrox_C PF05373.11 XP_666206.1 - 0.033 14.3 1.8 0.87 9.7 0.1 3.0 2 1 1 3 3 3 0 L-proline 3-hydroxylase, C-terminal DUF3300 PF11737.8 XP_666210.1 - 0.0088 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3300) HofP PF10748.9 XP_666210.1 - 0.041 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA utilization proteins HofP Glycos_transf_2 PF00535.26 XP_666213.1 - 1.3e-18 67.4 0.0 5.5e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 XP_666213.1 - 0.0022 17.6 0.5 0.0059 16.2 0.5 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ricin_B_lectin PF00652.22 XP_666213.1 - 0.0025 18.1 0.1 0.0025 18.1 0.1 3.9 5 0 0 5 5 5 1 Ricin-type beta-trefoil lectin domain Sigma_reg_N PF13800.6 XP_666213.1 - 9.1 6.7 12.9 14 6.0 0.2 3.0 2 1 0 2 2 2 0 Sigma factor regulator N-terminal Ribonuc_red_lgC PF02867.15 XP_666214.1 - 6.8e-158 526.5 0.0 8.1e-158 526.2 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain RNB PF00773.19 XP_666217.1 - 3e-93 312.7 6.3 4.3e-93 312.2 6.3 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 XP_666217.1 - 7e-20 70.8 0.0 1.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 XP_666217.1 - 4.7e-09 36.3 0.1 3.4e-07 30.4 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain Cadherin_5 PF17892.1 XP_666217.1 - 0.054 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Cadherin-like domain Rrp44_CSD1 PF17216.3 XP_666217.1 - 0.18 11.5 4.4 0.1 12.3 1.5 2.1 2 0 0 2 2 2 0 Rrp44-like cold shock domain SieB PF14163.6 XP_666219.1 - 0.024 14.1 0.4 0.041 13.4 0.4 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4131 PF13567.6 XP_666219.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HMG_box PF00505.19 XP_666220.1 - 4.8e-21 75.0 2.0 4.8e-21 75.0 2.0 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 XP_666220.1 - 1.2e-16 61.0 5.2 1.7e-16 60.6 5.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 XP_666220.1 - 0.00044 20.2 1.8 0.00044 20.2 1.8 1.7 1 1 1 2 2 2 1 HMG (high mobility group) box 5 Imm58 PF15581.6 XP_666220.1 - 0.032 14.3 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 58 PFK PF00365.20 XP_666221.1 - 9.1e-62 208.9 0.0 2.6e-37 128.7 0.0 3.6 4 0 0 4 4 4 2 Phosphofructokinase Serglycin PF04360.12 XP_666221.1 - 0.084 12.8 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Serglycin DUF1643 PF07799.12 XP_666221.1 - 0.15 12.3 0.0 28 4.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) DUF2431 PF10354.9 XP_666222.1 - 0.009 16.3 0.3 0.013 15.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) U3_assoc_6 PF08640.11 XP_666222.1 - 0.2 11.7 3.2 0.61 10.2 0.5 2.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 LMBR1 PF04791.16 XP_666222.1 - 4.4 6.1 10.6 5.3 5.8 10.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Proteasome PF00227.26 XP_666223.1 - 2.8e-09 36.7 0.0 3e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UQ_con PF00179.26 XP_666225.1 - 6e-24 84.3 0.0 6.5e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AdoMet_Synthase PF01941.19 XP_666225.1 - 0.037 12.8 0.0 0.042 12.6 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Pkinase PF00069.25 XP_666226.1 - 4.1e-28 98.5 0.9 4.1e-28 98.5 0.9 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666226.1 - 0.00056 19.3 0.2 0.016 14.5 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_666226.1 - 0.0044 16.4 0.0 0.078 12.3 0.0 2.5 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 XP_666226.1 - 0.029 14.0 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3584 PF12128.8 XP_666227.1 - 2.7e-06 25.2 14.6 2.7e-06 25.2 14.6 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) FAM184 PF15665.5 XP_666227.1 - 0.011 15.5 28.2 0.049 13.4 24.5 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B OmpH PF03938.14 XP_666227.1 - 0.13 12.6 32.1 0.12 12.7 10.4 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DNA_photolyase PF00875.18 XP_666227.1 - 0.19 11.7 1.9 1.1 9.3 0.6 2.2 1 1 1 2 2 2 0 DNA photolyase T7SS_ESX_EspC PF10824.8 XP_666227.1 - 0.53 10.8 3.5 2.2 8.8 0.3 3.1 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF3641 PF12345.8 XP_666227.1 - 0.7 9.9 12.3 0.43 10.6 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Cep57_MT_bd PF06657.13 XP_666227.1 - 0.75 10.3 12.2 0.42 11.1 0.5 3.4 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Mst1_SARAH PF11629.8 XP_666227.1 - 0.89 9.7 12.7 0.64 10.2 1.1 3.9 3 1 1 4 4 4 0 C terminal SARAH domain of Mst1 Nbl1_Borealin_N PF10444.9 XP_666227.1 - 0.89 9.2 10.6 0.75 9.5 0.3 4.4 4 2 2 6 6 6 0 Nbl1 / Borealin N terminal DUF1664 PF07889.12 XP_666227.1 - 1 9.4 14.9 0.74 9.9 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 XP_666227.1 - 1.2 9.0 26.5 0.33 10.9 5.7 3.8 2 2 2 4 4 4 0 Bacteriophage Mu Gam like protein Phage_lysis PF03245.13 XP_666227.1 - 1.3 9.2 14.3 0.045 13.9 3.2 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein PocR PF10114.9 XP_666227.1 - 2.1 8.1 7.0 1 9.1 0.7 2.5 2 0 0 2 2 2 0 Sensory domain found in PocR KfrA_N PF11740.8 XP_666227.1 - 2.9 8.6 8.8 2.9 8.6 0.6 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term ApoLp-III PF07464.11 XP_666227.1 - 3 7.9 25.3 8.8 6.4 5.1 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 XP_666227.1 - 3.2 7.8 14.5 0.074 13.1 3.0 2.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 XP_666227.1 - 3.6 6.9 22.4 0.34 10.2 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Muted PF14942.6 XP_666227.1 - 4.7 7.6 31.8 0.052 13.9 5.1 3.0 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF3086 PF11285.8 XP_666227.1 - 7.5 5.6 12.4 0.46 9.5 4.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3086) Coq4 PF05019.13 XP_666228.1 - 3.2e-30 105.1 0.0 4e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pox_L5 PF04872.13 XP_666228.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Poxvirus L5 protein family AAA_5 PF07728.14 XP_666229.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDEase_I PF00233.19 XP_666230.1 - 3.7e-66 223.2 0.0 9.2e-66 222.0 0.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Wzy_C PF04932.15 XP_666231.1 - 0.0015 18.2 3.7 0.002 17.8 3.7 1.4 1 0 0 1 1 1 1 O-Antigen ligase DEAD PF00270.29 XP_666233.1 - 4.1e-44 150.4 0.0 1e-43 149.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_666233.1 - 8.4e-26 90.5 0.1 8.4e-26 90.5 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 XP_666233.1 - 8.3e-09 35.6 4.9 8.3e-09 35.6 4.9 2.1 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 XP_666233.1 - 2.4e-07 30.2 0.2 6e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 XP_666233.1 - 0.063 13.5 0.3 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF536 PF04394.14 XP_666233.1 - 7.1 6.6 6.8 18 5.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF536 Methyltransf_11 PF08241.12 XP_666234.1 - 2e-13 50.8 0.1 4.3e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_666234.1 - 1.1e-12 48.4 0.1 2e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666234.1 - 1.9e-08 34.9 0.0 3.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_666234.1 - 1.9e-08 34.3 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666234.1 - 3.3e-06 27.0 0.1 6.9e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 XP_666234.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 XP_666234.1 - 0.0094 14.9 0.0 0.042 12.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 XP_666234.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) TRAF_BIRC3_bd PF16673.5 XP_666234.1 - 0.14 11.9 0.4 9.6 6.1 0.0 3.2 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain HA2 PF04408.23 XP_666235.1 - 3.3e-22 78.8 0.0 9.4e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 XP_666235.1 - 6.5e-13 48.8 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 XP_666235.1 - 4.6e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 XP_666235.1 - 3e-06 27.1 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 XP_666235.1 - 4.5e-06 27.0 0.0 1.5e-05 25.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 XP_666235.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 XP_666235.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 XP_666235.1 - 0.0004 20.8 0.0 0.00071 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 XP_666235.1 - 0.00051 19.8 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 XP_666235.1 - 0.0094 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 XP_666235.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 XP_666235.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 XP_666235.1 - 0.063 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 XP_666235.1 - 0.072 13.1 0.1 6.9 6.6 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 XP_666235.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 XP_666235.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 XP_666235.1 - 0.14 12.3 0.2 0.32 11.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 XP_666236.1 - 0.00021 21.0 0.1 0.00042 20.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_N PF00134.23 XP_666237.1 - 8.3e-09 35.3 4.0 1.5e-06 28.0 0.6 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 XP_666237.1 - 9.7e-07 28.9 0.1 2.5e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Baculo_PEP_C PF04513.12 XP_666238.1 - 0.00087 19.3 5.4 0.24 11.5 0.2 2.7 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 XP_666238.1 - 0.0043 16.9 3.6 0.64 9.8 0.5 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE PF05739.19 XP_666238.1 - 0.022 14.8 0.1 0.022 14.8 0.1 1.9 2 0 0 2 2 1 0 SNARE domain HSBP1 PF06825.12 XP_666238.1 - 0.03 14.2 3.8 0.87 9.5 1.2 3.4 3 1 0 3 3 2 0 Heat shock factor binding protein 1 LOH1CR12 PF10158.9 XP_666238.1 - 0.033 14.2 0.7 0.033 14.2 0.7 2.1 2 0 0 2 2 2 0 Tumour suppressor protein ABC_tran_CTD PF16326.5 XP_666238.1 - 0.041 14.1 8.5 0.053 13.8 2.2 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 XP_666238.1 - 0.048 14.0 0.5 0.048 14.0 0.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GGDEF PF00990.21 XP_666238.1 - 0.065 13.0 2.8 0.72 9.6 0.4 2.4 2 1 0 2 2 2 0 Diguanylate cyclase, GGDEF domain Laminin_II PF06009.12 XP_666238.1 - 0.24 11.4 8.6 0.98 9.4 2.5 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 XP_666238.1 - 0.24 11.7 11.5 0.78 10.0 0.3 3.0 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Lipoprotein_7 PF01540.16 XP_666238.1 - 0.31 10.3 8.3 1.2 8.3 3.2 2.4 2 1 0 2 2 2 0 Adhesin lipoprotein DUF1664 PF07889.12 XP_666238.1 - 0.32 11.1 9.5 0.69 10.0 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) PBECR1 PF18809.1 XP_666238.1 - 0.58 10.8 0.1 0.58 10.8 0.1 3.3 3 1 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 TMF_DNA_bd PF12329.8 XP_666238.1 - 0.78 9.8 14.1 0.16 11.9 4.0 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 XP_666238.1 - 0.87 10.1 15.5 0.52 10.8 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF16 Goodbye PF17109.5 XP_666238.1 - 0.92 10.0 5.3 11 6.4 0.0 3.4 2 2 1 3 3 3 0 fungal STAND N-terminal Goodbye domain UPF0242 PF06785.11 XP_666238.1 - 1.2 9.2 19.3 6.2 6.9 12.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 XP_666238.1 - 1.7 8.8 19.6 1.3 9.2 2.0 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family LPP PF04728.13 XP_666238.1 - 2.6 8.5 8.8 42 4.6 0.2 4.1 3 1 1 4 4 4 0 Lipoprotein leucine-zipper KxDL PF10241.9 XP_666238.1 - 3.3 8.0 9.3 0.56 10.5 2.7 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein FlaC_arch PF05377.11 XP_666238.1 - 4 7.9 9.2 3.2 8.2 2.7 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 XP_666238.1 - 4.3 7.0 7.1 7.1 6.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) IFT57 PF10498.9 XP_666238.1 - 4.3 6.2 17.2 0.39 9.6 0.6 2.6 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Med21 PF11221.8 XP_666238.1 - 5.3 7.3 9.7 1.4 9.2 3.2 2.9 2 2 0 2 2 2 0 Subunit 21 of Mediator complex RseA_C PF03873.13 XP_666239.1 - 1.8e-09 37.7 19.8 2.9 8.2 0.0 11.3 4 4 10 14 14 14 7 Anti sigma-E protein RseA, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 XP_666240.1 - 8.2e-07 29.8 0.1 1.7e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 XP_666241.1 - 1.2e-47 161.9 0.3 4.5e-47 160.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_666241.1 - 3.4e-23 82.1 0.0 2.4e-22 79.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 XP_666241.1 - 7.7e-17 61.3 0.8 1.6e-16 60.3 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 XP_666241.1 - 1.6e-05 24.9 0.0 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 XP_666241.1 - 0.034 13.9 0.0 1 9.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain Ribosomal_L27A PF00828.19 XP_666242.1 - 1.5e-15 58.0 0.0 1.7e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1688 PF07958.11 XP_666242.1 - 0.19 10.4 0.0 0.23 10.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) BBP1_N PF15271.6 XP_666243.1 - 0.009 16.8 2.4 0.009 16.8 2.4 2.1 2 0 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein Piezo_RRas_bdg PF12166.8 XP_666243.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain OppC_N PF12911.7 XP_666243.1 - 0.17 11.9 0.2 0.3 11.1 0.2 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Zn_Tnp_IS1595 PF12760.7 XP_666244.1 - 0.12 12.4 1.7 0.25 11.4 1.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ATP_bind_1 PF03029.17 XP_666245.1 - 6.1e-81 271.7 0.1 6.9e-81 271.6 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 XP_666245.1 - 0.00056 20.5 0.2 0.0017 18.9 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 XP_666245.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 XP_666245.1 - 0.016 15.2 0.0 0.14 12.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 XP_666245.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 XP_666245.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 XP_666245.1 - 0.047 14.1 0.1 0.24 11.8 0.1 2.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_17 PF13207.6 XP_666245.1 - 0.05 14.0 0.2 0.1 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 XP_666245.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 XP_666245.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 XP_666245.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain CS PF04969.16 XP_666246.1 - 2.2e-05 25.4 2.1 4.7e-05 24.3 1.8 1.8 1 1 0 1 1 1 1 CS domain CDC37_N PF03234.14 XP_666246.1 - 0.0011 19.8 1.4 0.0011 19.8 1.4 2.3 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding COG7 PF10191.9 XP_666247.1 - 0.00022 19.6 1.0 0.00023 19.6 0.6 1.4 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) Turandot PF07240.11 XP_666247.1 - 0.24 11.4 1.4 0.41 10.6 0.3 1.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Med14 PF08638.11 XP_666248.1 - 3.7e-11 42.8 0.0 7.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 TP6A_N PF04406.14 XP_666249.1 - 1.6e-17 63.3 0.6 5.1e-17 61.6 0.2 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase ADIP PF11559.8 XP_666249.1 - 0.06 13.4 1.9 0.19 11.8 0.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPT PF03151.16 XP_666251.1 - 1.3e-13 50.9 19.1 1.6e-13 50.7 19.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 XP_666251.1 - 0.021 15.0 17.9 6.5 6.9 0.0 3.0 2 1 0 2 2 2 0 EamA-like transporter family PUNUT PF16913.5 XP_666251.1 - 0.038 13.2 19.2 0.21 10.8 18.8 2.0 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport IMPDH PF00478.25 XP_666252.1 - 1.9e-21 76.5 0.1 2.1e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF3929 PF13066.6 XP_666254.1 - 0.09 12.8 0.4 0.37 10.9 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3929) RPN6_N PF18055.1 XP_666255.1 - 4.8e-35 120.4 0.8 1.3e-34 119.1 0.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 XP_666255.1 - 6.6e-15 55.5 3.2 6.6e-15 55.5 3.2 2.6 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 XP_666255.1 - 2.5e-05 23.9 0.1 5.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DUF410 PF04190.13 XP_666255.1 - 0.0011 18.8 0.7 1.1 9.0 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_12 PF13424.6 XP_666255.1 - 0.0066 16.7 1.0 5.6 7.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DDRGK PF09756.9 XP_666255.1 - 0.03 13.9 0.8 0.057 13.0 0.8 1.4 1 0 0 1 1 1 0 DDRGK domain RcbX PF02341.15 XP_666255.1 - 0.04 14.2 1.0 0.8 10.0 0.1 2.9 2 0 0 2 2 2 0 RbcX protein NAD_binding_6 PF08030.12 XP_666255.1 - 0.1 12.7 0.8 0.25 11.5 0.8 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PMC2NT PF08066.12 XP_666255.1 - 1.7 9.3 4.5 2.4 8.9 0.5 3.3 2 1 2 4 4 4 0 PMC2NT (NUC016) domain TPR_2 PF07719.17 XP_666255.1 - 5.3 7.4 6.9 31 5.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DER1 PF04511.15 XP_666256.1 - 1.8e-34 119.4 8.2 2.6e-34 118.9 8.2 1.2 1 0 0 1 1 1 1 Der1-like family WIF PF02019.18 XP_666256.1 - 0.033 13.9 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 WIF domain DUF2070 PF09843.9 XP_666256.1 - 7.8 4.7 7.2 9.6 4.4 7.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Myotub-related PF06602.14 XP_666257.1 - 3e-121 404.6 0.8 7.7e-121 403.3 0.8 1.7 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 XP_666257.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 XP_666257.1 - 0.009 15.8 0.7 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 XP_666257.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_M22 PF00814.25 XP_666259.1 - 7.4e-52 176.7 0.0 8.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PilO PF04350.13 XP_666261.1 - 0.019 15.1 0.1 0.061 13.5 0.1 1.8 1 0 0 1 1 1 0 Pilus assembly protein, PilO Vps16_N PF04841.13 XP_666263.1 - 2.9e-38 131.7 0.0 5.9e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 XP_666263.1 - 1.6e-18 66.9 6.6 2.3e-09 36.8 0.7 2.8 1 1 1 2 2 2 2 Vps16, C-terminal region DUF4834 PF16118.5 XP_666264.1 - 0.22 12.5 3.7 3.4 8.7 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5383 PF17355.2 XP_666264.1 - 3.3 8.1 7.4 0.78 10.1 3.0 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5383) RhoGEF67_u2 PF16614.5 XP_666265.1 - 0.72 10.0 4.8 0.91 9.6 0.7 2.4 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 LAGLIDADG_3 PF14528.6 XP_666265.1 - 5.8 7.3 13.8 0.37 11.1 0.7 3.3 2 2 1 3 3 3 0 LAGLIDADG-like domain DUF3800 PF12686.7 XP_666265.1 - 6 7.5 7.0 24 5.6 7.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF2075 PF09848.9 XP_666269.1 - 0.044 13.0 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Tfb2 PF03849.14 XP_666271.1 - 2.7e-23 82.5 2.0 1.4e-18 67.0 0.2 2.1 1 1 1 2 2 2 2 Transcription factor Tfb2 UPF0261 PF06792.11 XP_666271.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Proteasome PF00227.26 XP_666272.1 - 2e-56 190.5 0.0 2.4e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 XP_666272.1 - 1.4e-12 47.0 0.1 2.3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF384 PF04064.13 XP_666273.1 - 1.4e-13 50.5 0.2 3.5e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF383 PF04063.14 XP_666273.1 - 3.3e-12 46.5 13.8 8.9e-08 32.0 4.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF383) RICTOR_M PF14666.6 XP_666273.1 - 0.0018 18.0 0.4 0.33 10.7 0.0 2.9 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain zf-RING_2 PF13639.6 XP_666274.1 - 0.96 9.8 6.9 0.26 11.6 0.7 2.5 2 0 0 2 2 2 0 Ring finger domain DUF3228 PF11539.8 XP_666275.1 - 3.2e-76 255.2 0.1 3.7e-76 255.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) PH_RBD PF12068.8 XP_666275.1 - 0.033 13.7 0.2 0.047 13.2 0.2 1.2 1 0 0 1 1 1 0 Rab-binding domain (RBD) DUF4261 PF14080.6 XP_666275.1 - 0.039 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) EF-hand_8 PF13833.6 XP_666276.1 - 2.6e-05 24.0 0.3 4.9e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 XP_666276.1 - 0.001 18.4 0.2 0.0022 17.4 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 XP_666276.1 - 0.0055 17.1 0.3 0.0095 16.4 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 XP_666276.1 - 0.024 14.5 0.4 0.067 13.2 0.4 1.8 1 0 0 1 1 1 0 EF-hand domain DUF4337 PF14235.6 XP_666276.1 - 0.095 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EF-hand_5 PF13202.6 XP_666276.1 - 0.17 11.4 0.6 0.44 10.1 0.6 1.6 1 0 0 1 1 1 0 EF hand Claudin_2 PF13903.6 XP_666276.1 - 0.38 10.5 3.7 4.7 6.9 0.3 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction COPI_assoc PF08507.10 XP_666277.1 - 0.00016 21.7 0.4 0.00022 21.3 0.4 1.2 1 0 0 1 1 1 1 COPI associated protein Phage_Gp15 PF06854.11 XP_666278.1 - 0.0096 15.9 0.6 0.0096 15.9 0.6 2.0 2 0 0 2 2 2 1 Bacteriophage Gp15 protein YycI PF09648.10 XP_666278.1 - 0.028 14.0 6.5 0.052 13.1 6.5 1.4 1 0 0 1 1 1 0 YycH protein ABC2_membrane_3 PF12698.7 XP_666278.1 - 0.038 13.1 4.9 0.051 12.7 4.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein V-SNARE_C PF12352.8 XP_666278.1 - 0.069 13.5 2.2 0.14 12.5 2.2 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF3519 PF12033.8 XP_666278.1 - 0.081 13.3 2.6 0.16 12.4 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) DUF5435 PF17503.2 XP_666279.1 - 1.8 8.2 5.7 4.3 7.0 1.3 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5435) Peptidase_M18 PF02127.15 XP_666280.1 - 2.5e-125 418.7 0.1 4.7e-125 417.8 0.1 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 XP_666280.1 - 7.7e-10 38.3 0.0 8.4e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Kelch_4 PF13418.6 XP_666281.1 - 1.2e-35 121.2 4.8 1.1e-09 38.2 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 XP_666281.1 - 2.1e-30 104.4 5.8 5.3e-07 29.8 0.0 7.3 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 XP_666281.1 - 3.4e-28 97.1 8.2 4.1e-07 29.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 XP_666281.1 - 3.1e-24 84.0 7.3 2.2e-06 27.4 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 XP_666281.1 - 1.2e-23 82.4 8.5 2e-06 27.3 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 XP_666281.1 - 3.6e-22 77.8 7.6 0.00057 20.1 0.0 6.3 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 XP_666281.1 - 6.3e-22 77.9 3.8 8.3e-22 77.5 1.7 2.1 1 1 1 2 2 2 1 BTB/POZ domain DUF1265 PF06887.14 XP_666281.1 - 0.016 15.1 9.9 0.59 10.1 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1265) BACK PF07707.15 XP_666281.1 - 0.042 13.9 1.2 0.55 10.4 0.1 2.8 3 0 0 3 3 3 0 BTB And C-terminal Kelch Glyco_transf_22 PF03901.17 XP_666282.1 - 4.3e-60 204.1 57.3 6.8e-60 203.4 57.3 1.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family MMR_HSR1_Xtn PF16897.5 XP_666284.1 - 6.2e-43 145.1 1.0 9.9e-43 144.5 1.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 XP_666284.1 - 7.4e-22 77.2 0.1 1.3e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 XP_666284.1 - 7.3e-21 74.4 0.0 2e-20 73.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_666284.1 - 2.9e-11 43.2 0.1 9.7e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 XP_666284.1 - 0.00077 18.5 0.3 0.0024 16.9 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 XP_666284.1 - 0.00078 19.5 0.1 0.98 9.5 0.2 2.4 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 XP_666284.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 XP_666284.1 - 0.11 12.5 0.1 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase CRM1_C PF08767.11 XP_666285.1 - 8.3e-78 261.8 19.3 7.5e-77 258.6 18.3 2.3 2 0 0 2 2 2 1 CRM1 C terminal CRM1_repeat_3 PF18787.1 XP_666285.1 - 2.9e-22 78.5 1.6 3.3e-21 75.1 0.8 2.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 DUF3412 PF11892.8 XP_666285.1 - 0.095 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) Pkinase PF00069.25 XP_666287.1 - 5.4e-70 235.8 0.0 6.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666287.1 - 9.9e-35 120.1 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_666287.1 - 2.6e-05 23.7 0.0 6.5e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 XP_666288.1 - 1.1e-68 231.5 0.0 1.6e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666288.1 - 1.3e-32 113.2 0.0 2.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 XP_666288.1 - 0.0033 16.8 0.4 0.01 15.2 0.4 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 XP_666288.1 - 0.0047 15.9 1.3 0.0075 15.3 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 XP_666288.1 - 0.046 13.4 0.5 0.21 11.2 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IF-2B PF01008.17 XP_666289.1 - 3.5e-47 160.9 0.5 3.9e-47 160.8 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PP_kinase_C_1 PF17941.1 XP_666289.1 - 0.0047 16.5 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 L_lactis_RepB_C PF06430.12 XP_666289.1 - 0.0056 16.7 0.1 0.088 12.8 0.0 2.5 2 0 0 2 2 2 1 Lactococcus lactis RepB C-terminus RNR_N PF08343.10 XP_666289.1 - 0.018 15.1 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal PA28_alpha PF02251.18 XP_666294.1 - 0.014 15.4 0.4 5.4 7.1 0.1 3.0 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit Cecropin PF00272.19 XP_666294.1 - 0.34 10.7 1.5 0.82 9.4 1.5 1.6 1 0 0 1 1 1 0 Cecropin family MutL_C PF08676.11 XP_666295.1 - 1.7e-19 70.0 1.0 5.8e-18 65.1 0.2 2.3 2 0 0 2 2 2 2 MutL C terminal dimerisation domain zf-RING_UBOX PF13445.6 XP_666296.1 - 0.013 15.5 2.3 0.013 15.5 2.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 XP_666296.1 - 0.58 10.4 8.4 6.1 7.1 3.7 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 XP_666296.1 - 0.87 10.0 9.8 5.4 7.4 3.0 2.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 XP_666296.1 - 1 9.3 12.3 1.2 9.1 5.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_666296.1 - 1.1 9.2 12.5 0.23 11.4 2.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_666296.1 - 1.2 9.2 11.5 0.081 12.9 3.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 XP_666296.1 - 3.4 7.6 13.4 7.8 6.5 5.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PRIMA1 PF16101.5 XP_666297.1 - 0.44 10.6 12.9 1.5 8.9 12.9 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4145 PF13643.6 XP_666297.1 - 4.2 7.6 11.5 0.15 12.2 0.3 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) HhH-GPD PF00730.25 XP_666298.1 - 7.8e-16 58.5 0.2 1.6e-15 57.4 0.1 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SBP_bac_5 PF00496.22 XP_666298.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle zf-RING_2 PF13639.6 XP_666300.1 - 8.3e-13 48.5 9.8 1.9e-12 47.3 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 XP_666300.1 - 3.9e-09 36.1 6.6 1.1e-08 34.6 6.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 XP_666300.1 - 1.3e-07 31.8 10.0 4.7e-07 30.0 10.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 XP_666300.1 - 6.5e-07 29.1 10.3 1.5e-06 27.9 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_666300.1 - 6.2e-06 25.9 8.7 1.1e-05 25.1 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_666300.1 - 0.00011 22.0 7.7 0.00021 21.1 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 XP_666300.1 - 0.00023 20.7 7.0 0.00051 19.6 7.0 1.6 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 XP_666300.1 - 0.0003 20.7 7.7 0.00067 19.6 7.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 XP_666300.1 - 0.0046 17.0 5.2 0.0055 16.7 3.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 XP_666300.1 - 0.0072 16.4 2.5 0.013 15.5 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 XP_666300.1 - 0.012 15.5 10.3 0.067 13.1 9.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF4692 PF15763.5 XP_666300.1 - 0.043 14.3 0.4 0.087 13.3 0.2 1.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) zf-RING_10 PF16685.5 XP_666300.1 - 0.044 13.9 4.8 0.079 13.1 4.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3H2C3 PF17122.5 XP_666300.1 - 0.2 11.7 7.3 0.083 12.9 4.3 2.0 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 XP_666300.1 - 1.7 8.8 9.4 3.6 7.8 9.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 XP_666300.1 - 1.9 8.7 9.1 39 4.5 9.1 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 XP_666300.1 - 1.9 8.5 8.0 2.2 8.3 3.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PAN_2 PF08276.11 XP_666301.1 - 0.009 16.1 0.0 0.009 16.1 0.0 4.0 4 1 1 5 5 5 1 PAN-like domain PAN_1 PF00024.26 XP_666301.1 - 0.015 15.3 15.0 1.3 9.1 8.2 3.4 3 1 0 3 3 3 0 PAN domain PAN_4 PF14295.6 XP_666301.1 - 0.2 11.6 0.1 0.2 11.6 0.1 3.7 3 1 0 3 3 3 0 PAN domain V-ATPase_H_C PF11698.8 XP_666302.1 - 0.054 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 V-ATPase subunit H START PF01852.19 XP_666305.1 - 3.5e-09 36.4 0.0 7.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 START domain OCRE PF17780.1 XP_666305.1 - 0.27 11.3 2.1 0.25 11.4 0.4 1.8 2 0 0 2 2 2 0 OCRE domain DnaJ PF00226.31 XP_666306.1 - 8.3e-14 51.5 0.5 1.3e-13 50.9 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4248 PF14053.6 XP_666306.1 - 0.044 13.8 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) RPT PF13446.6 XP_666306.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein MFS_1 PF07690.16 XP_666307.1 - 1.4e-07 30.7 15.1 1.4e-07 30.7 15.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.25 XP_666308.1 - 1e-77 261.0 0.0 1.7e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666308.1 - 8.7e-33 113.7 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 XP_666308.1 - 1.9e-26 89.6 7.6 2.1e-06 26.8 1.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_666308.1 - 6.4e-25 87.4 4.0 2.9e-12 46.8 0.9 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 XP_666308.1 - 6.8e-23 79.1 5.5 1e-06 28.0 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 XP_666308.1 - 2.3e-21 73.8 5.3 3.6e-05 23.3 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 XP_666308.1 - 4.9e-19 67.9 9.2 1.7e-09 37.4 1.0 4.3 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 XP_666308.1 - 3.5e-07 30.5 0.7 0.017 15.4 0.3 2.7 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 XP_666308.1 - 8.9e-06 25.9 0.4 0.0024 18.2 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 XP_666308.1 - 0.00083 19.3 2.6 0.34 10.9 0.5 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand APH PF01636.23 XP_666308.1 - 0.001 19.1 0.0 0.0027 17.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 XP_666308.1 - 0.019 13.8 0.4 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 XP_666308.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_13 PF17958.1 XP_666308.1 - 0.1 12.4 0.1 30 4.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DUF842 PF05811.13 XP_666309.1 - 0.027 14.1 2.2 0.054 13.2 2.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Orf78 PF06024.12 XP_666309.1 - 1.9 8.9 4.4 2.8 8.3 0.1 2.7 2 0 0 2 2 2 0 Orf78 (ac78) Menin PF05053.13 XP_666309.1 - 2 6.7 5.3 2.8 6.2 5.3 1.2 1 0 0 1 1 1 0 Menin DDHD PF02862.17 XP_666310.1 - 2.5e-38 132.5 0.7 2.4e-36 126.0 0.0 2.7 3 0 0 3 3 3 1 DDHD domain DUF676 PF05057.14 XP_666310.1 - 3.4e-05 23.5 1.9 0.00035 20.1 1.9 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 XP_666310.1 - 0.00052 19.6 0.7 0.001 18.7 0.3 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 XP_666310.1 - 0.0012 18.7 0.1 0.034 13.9 0.0 2.6 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 XP_666310.1 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 XP_666310.1 - 0.0051 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 XP_666310.1 - 0.013 14.8 0.0 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_666310.1 - 0.014 15.0 0.0 0.056 13.1 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 XP_666310.1 - 0.028 15.0 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family StbA PF06406.11 XP_666310.1 - 0.056 12.7 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 StbA protein Guanylate_cyc PF00211.20 XP_666311.1 - 1.5e-14 54.1 0.0 4.4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Afaf PF15339.6 XP_666311.1 - 0.61 9.8 5.0 1.7 8.3 0.5 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor NUDIX_4 PF14815.6 XP_666313.1 - 0.0081 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DS PF01916.17 XP_666314.1 - 5.9e-55 186.5 0.0 7.4e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MIF4G PF02854.19 XP_666315.1 - 9.4e-31 107.1 5.9 2.8e-30 105.6 5.9 1.9 1 0 0 1 1 1 1 MIF4G domain AAA_14 PF13173.6 XP_666315.1 - 0.011 15.8 0.1 0.091 12.8 0.1 2.7 1 0 0 1 1 1 0 AAA domain Bac_rhamnosid_N PF08531.10 XP_666317.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain NPR1_interact PF15699.5 XP_666317.1 - 2.2 8.9 0.0 2.2 8.9 0.0 2.9 3 0 0 3 3 3 0 NPR1 interacting BsuBI_PstI_RE PF06616.11 XP_666319.1 - 0.06 12.6 1.6 0.17 11.2 0.4 2.3 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain zf-met2 PF12907.7 XP_666320.1 - 4.7e-18 65.0 1.6 8.1e-18 64.3 1.6 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 XP_666320.1 - 0.0016 19.2 3.2 0.0028 18.5 3.2 1.4 1 0 0 1 1 1 1 4F5 protein family DUF5561 PF17716.1 XP_666320.1 - 0.0057 16.0 0.2 0.0065 15.8 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5561) FANCI_S3 PF14677.6 XP_666320.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.0 1 0 0 1 1 1 0 FANCI solenoid 3 zf-C2H2_4 PF13894.6 XP_666320.1 - 0.019 15.8 0.2 0.05 14.5 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger PDZ_4 PF17816.1 XP_666321.1 - 0.035 14.5 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Filaggrin PF03516.13 XP_666322.1 - 0.57 11.0 5.7 1 10.2 5.7 1.4 1 1 0 1 1 1 0 Filaggrin Nop14 PF04147.12 XP_666323.1 - 0.016 13.4 30.1 0.021 13.1 30.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1682 PF07946.14 XP_666326.1 - 0.2 10.8 33.7 0.32 10.2 31.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 XP_666327.1 - 4.2e-68 229.6 0.0 4.5e-34 118.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666327.1 - 3.4e-27 95.4 0.0 4.2e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.6 XP_666327.1 - 1.5e-11 43.3 0.6 0.016 15.1 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 XP_666327.1 - 5e-08 33.3 1.5 0.0014 19.1 0.1 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 XP_666327.1 - 7.5e-07 28.3 1.0 0.005 16.3 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 XP_666327.1 - 9.1e-07 28.1 0.7 0.0064 15.9 0.2 3.2 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 XP_666327.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.6 XP_666327.1 - 0.14 12.1 2.6 11 5.9 0.0 4.2 5 0 0 5 5 5 0 EF-hand domain pair Metallophos PF00149.28 XP_666328.1 - 2.4e-32 113.1 0.7 4.5e-32 112.2 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_5 PF13854.6 XP_666328.1 - 2.6e-11 43.2 0.1 3.8e-05 23.6 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 XP_666328.1 - 3.5e-08 32.9 0.3 0.00071 19.1 0.0 3.3 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 XP_666328.1 - 5e-08 32.8 2.4 0.0052 16.8 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 XP_666328.1 - 3.2e-07 30.1 0.6 0.00056 19.8 0.1 3.3 2 1 1 3 3 3 2 Kelch motif Kelch_6 PF13964.6 XP_666328.1 - 5e-05 23.4 0.0 0.56 10.6 0.0 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 XP_666328.1 - 0.012 15.9 0.0 0.012 15.9 0.0 4.7 6 0 0 6 6 6 0 Galactose oxidase, central domain PPP4R2 PF09184.11 XP_666329.1 - 2.7e-08 33.8 1.6 2.7e-08 33.8 1.6 1.9 1 1 0 2 2 2 1 PPP4R2 zf_UBZ PF18439.1 XP_666329.1 - 0.025 14.2 1.0 0.18 11.4 1.0 2.4 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger NAGLU_N PF12971.7 XP_666329.1 - 0.073 12.9 0.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Carbpep_Y_N PF05388.11 XP_666330.1 - 0.064 13.8 0.7 0.25 11.9 0.5 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide KRTAP PF11759.8 XP_666332.1 - 0.21 12.1 36.1 1.5 9.5 18.1 2.4 1 1 1 2 2 2 0 Keratin-associated matrix Ly49 PF08391.10 XP_666333.1 - 0.0042 17.4 0.9 0.0056 17.0 0.9 1.1 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region PIEZO PF15917.5 XP_666333.1 - 0.0042 16.6 3.7 0.0054 16.2 3.7 1.2 1 0 0 1 1 1 1 Piezo GAPT PF11770.8 XP_666333.1 - 0.0071 16.2 0.2 0.0086 16.0 0.2 1.2 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) Peptidase_S49_N PF08496.10 XP_666333.1 - 0.012 15.7 1.8 0.015 15.4 1.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4758 PF15950.5 XP_666333.1 - 0.096 13.0 0.2 0.12 12.8 0.2 1.1 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein PsbL PF02419.17 XP_666333.1 - 0.27 11.2 2.9 0.42 10.6 2.9 1.3 1 0 0 1 1 1 0 PsbL protein ETRAMP PF09716.10 XP_666333.1 - 0.49 10.5 2.8 1.5 9.0 2.8 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) V_ATPase_I PF01496.19 XP_666334.1 - 9.3e-255 847.5 7.6 1.1e-254 847.2 7.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FAM184 PF15665.5 XP_666334.1 - 4.5 7.0 6.4 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B AARP2CN PF08142.12 XP_666335.1 - 1.6e-10 40.9 0.1 2.8e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 XP_666335.1 - 0.00012 21.7 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 XP_666335.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EF-hand_6 PF13405.6 XP_666337.1 - 0.0007 19.3 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 XP_666337.1 - 0.0027 17.5 0.0 0.02 14.7 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 XP_666337.1 - 0.0031 17.9 0.0 0.0038 17.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 XP_666337.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 EF hand VPS13 PF16908.5 XP_666338.1 - 6.3e-13 49.1 0.0 1.3e-11 44.8 0.0 2.9 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 XP_666338.1 - 1.5e-05 25.1 0.2 1.5e-05 25.1 0.2 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Trypan_PARP PF05887.11 XP_666338.1 - 0.19 11.7 8.3 0.4 10.7 8.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 XP_666338.1 - 0.27 10.8 9.1 0.53 9.9 9.1 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) NUDIX PF00293.28 XP_666341.1 - 2.7e-08 33.9 0.0 6.1e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain SNF2_N PF00176.23 XP_666342.1 - 2.6e-50 171.1 0.4 6.9e-50 169.7 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.29 XP_666342.1 - 3.5e-19 68.4 68.5 1.4e-09 37.7 5.3 6.5 6 0 0 6 6 6 5 PHD-finger Helicase_C PF00271.31 XP_666342.1 - 1.3e-12 48.0 0.0 4.2e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD_2 PF13831.6 XP_666342.1 - 0.00014 21.4 0.8 0.00014 21.4 0.8 6.9 7 0 0 7 7 7 1 PHD-finger ResIII PF04851.15 XP_666342.1 - 0.00038 20.5 0.0 0.00038 20.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zf_RING PF16744.5 XP_666342.1 - 3.2 7.9 31.2 0.15 12.1 2.5 5.3 4 1 0 4 4 4 0 KIAA1045 RING finger ELO PF01151.18 XP_666343.1 - 9.9e-68 228.4 25.0 1.3e-67 228.0 25.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mod_r PF07200.13 XP_666344.1 - 0.0026 17.9 3.0 0.0056 16.8 3.0 1.6 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Uds1 PF15456.6 XP_666344.1 - 0.16 12.2 3.4 0.2 11.8 1.9 1.9 1 1 0 1 1 1 0 Up-regulated During Septation MbeD_MobD PF04899.12 XP_666345.1 - 0.028 14.5 1.6 0.039 14.1 0.1 2.1 2 0 0 2 2 2 0 MbeD/MobD like PRiA4_ORF3 PF07929.11 XP_666345.1 - 1.6 8.4 5.7 3.5 7.3 5.7 1.7 1 1 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Cnl2_NKP2 PF09447.10 XP_666346.1 - 6.1 7.1 12.0 2.5 8.3 1.6 3.8 3 1 0 3 3 3 0 Cnl2/NKP2 family protein Iron_permease PF04120.12 XP_666347.1 - 0.08 12.7 0.2 0.25 11.1 0.2 1.8 1 0 0 1 1 1 0 Low affinity iron permease DUF3755 PF12579.8 XP_666348.1 - 0.02 14.5 0.1 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) RabGAP-TBC PF00566.18 XP_666348.1 - 0.024 14.3 0.6 0.028 14.1 0.6 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain HECT PF00632.25 XP_666349.1 - 4.7e-97 325.2 0.1 7.1e-97 324.6 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MA3 PF02847.17 XP_666350.1 - 8.5e-16 57.9 9.2 3.6e-07 30.1 0.3 3.8 3 1 0 3 3 3 3 MA3 domain Dopey_N PF04118.14 XP_666351.1 - 7.3e-91 304.5 1.5 7.3e-91 304.5 1.5 3.4 4 0 0 4 4 4 1 Dopey, N-terminal DASH_Ask1 PF08655.10 XP_666352.1 - 0.00021 21.1 0.0 0.00021 21.1 0.0 1.9 2 0 0 2 2 2 1 DASH complex subunit Ask1 DUF4420 PF14390.6 XP_666352.1 - 0.033 13.4 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) MMS1_N PF10433.9 XP_666354.1 - 6.2e-115 384.6 0.2 9.9e-115 383.9 0.2 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 XP_666354.1 - 2.2e-73 247.4 0.4 1.3e-69 235.0 0.1 3.0 3 0 0 3 3 3 2 CPSF A subunit region GMC_oxred_N PF00732.19 XP_666355.1 - 8.9e-11 41.7 0.0 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 XP_666355.1 - 9.2e-09 36.0 0.0 2.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 XP_666355.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 XP_666355.1 - 0.0047 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 XP_666355.1 - 0.062 13.5 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1764 PF08576.10 XP_666355.1 - 0.54 11.2 12.0 0.29 12.1 1.6 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) HMG_box PF00505.19 XP_666356.1 - 7.6e-15 55.1 2.8 1.3e-14 54.4 2.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 XP_666356.1 - 7.1e-11 42.5 1.8 1.2e-10 41.9 1.8 1.4 1 0 0 1 1 1 1 HMG-box domain DUF2448 PF10476.9 XP_666358.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF1664 PF07889.12 XP_666359.1 - 0.015 15.3 1.5 0.015 15.3 1.5 8.7 4 1 5 9 9 9 0 Protein of unknown function (DUF1664) UCH PF00443.29 XP_666360.1 - 1.9e-50 171.8 0.0 3.4e-49 167.7 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_666360.1 - 4e-17 62.8 0.4 5.4e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 XP_666360.1 - 0.0074 16.0 0.1 0.032 13.9 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal Drc1-Sld2 PF11719.8 XP_666361.1 - 9.1e-05 22.2 1.3 9.1e-05 22.2 1.3 1.9 1 1 1 2 2 2 1 DNA replication and checkpoint protein TolA_bind_tri PF16331.5 XP_666361.1 - 0.0058 16.7 1.6 0.034 14.2 0.5 2.5 3 0 0 3 3 3 1 TolA binding protein trimerisation Secretin_N_2 PF07655.13 XP_666361.1 - 0.021 15.3 1.9 0.06 13.9 1.9 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain EHD_N PF16880.5 XP_666361.1 - 0.29 11.1 5.5 2.5 8.1 3.8 2.6 2 0 0 2 2 2 0 N-terminal EH-domain containing protein DUF4709 PF15821.5 XP_666361.1 - 1.3 9.4 6.9 1 9.7 5.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) Fzo_mitofusin PF04799.13 XP_666361.1 - 2.6 7.6 7.6 2.6 7.6 0.6 2.8 3 0 0 3 3 3 0 fzo-like conserved region Phasin PF05597.11 XP_666362.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TcpA PF05946.12 XP_666362.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Myosin_head PF00063.21 XP_666363.1 - 7.5e-184 612.7 1.3 9.4e-184 612.4 1.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 XP_666363.1 - 0.0021 18.4 0.0 0.0084 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2780 PF11075.8 XP_666363.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) AAA_16 PF13191.6 XP_666363.1 - 0.097 13.0 0.4 0.31 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Cyclin PF08613.11 XP_666364.1 - 3.9e-29 102.1 0.9 1e-28 100.7 0.9 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 XP_666364.1 - 3.4e-08 33.3 0.1 6.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain HSBP1 PF06825.12 XP_666365.1 - 4.4e-12 45.7 3.0 7.4e-12 44.9 3.0 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 XP_666365.1 - 0.0023 18.2 2.3 0.086 13.2 0.3 2.1 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 XP_666365.1 - 0.016 15.2 2.5 0.022 14.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 XP_666365.1 - 0.026 14.5 5.5 0.048 13.7 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) V-SNARE PF05008.15 XP_666365.1 - 0.033 14.5 2.0 0.082 13.3 0.7 1.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Fzo_mitofusin PF04799.13 XP_666365.1 - 0.053 13.1 2.9 0.067 12.7 2.9 1.2 1 0 0 1 1 1 0 fzo-like conserved region YlqD PF11068.8 XP_666365.1 - 0.21 12.0 4.9 0.22 11.9 0.8 2.0 1 1 1 2 2 2 0 YlqD protein Pkinase PF00069.25 XP_666367.1 - 3e-31 108.8 1.0 3.2e-31 108.6 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666367.1 - 2e-20 73.2 0.2 2.1e-20 73.1 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_666367.1 - 8.9e-05 21.4 0.1 0.00012 21.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 XP_666367.1 - 0.00047 20.2 0.0 0.0041 17.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 XP_666367.1 - 0.049 13.0 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 Kinase-like COG4 PF08318.12 XP_666368.1 - 9.5e-14 51.2 2.6 9.5e-14 51.2 2.6 1.9 2 0 0 2 2 2 1 COG4 transport protein DASH_Duo1 PF08651.10 XP_666368.1 - 0.57 10.0 10.0 4.9 7.0 0.0 4.1 4 1 0 4 4 4 0 DASH complex subunit Duo1 Ribophorin_II PF05817.14 XP_666369.1 - 2.7e-10 39.5 8.5 2.7e-10 39.5 8.5 1.8 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S10 PF00338.22 XP_666370.1 - 2.7e-28 98.1 0.2 3.3e-28 97.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 XP_666370.1 - 0.03 15.1 0.2 0.061 14.2 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Pkinase PF00069.25 XP_666371.1 - 5.5e-58 196.4 0.0 1.9e-57 194.6 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666371.1 - 1.4e-37 129.4 0.0 3.4e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_666371.1 - 6.6e-06 25.7 0.1 2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 XP_666371.1 - 0.00012 21.0 0.1 0.00067 18.5 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase EF-hand_11 PF08976.11 XP_666371.1 - 0.00037 21.3 0.0 0.0011 19.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain APH PF01636.23 XP_666371.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M16 PF00675.20 XP_666373.1 - 9e-14 51.7 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_666373.1 - 4.7e-10 39.8 0.6 5e-08 33.2 0.1 2.4 2 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_666374.1 - 6e-07 29.6 0.0 6e-07 29.6 0.0 3.2 2 1 0 2 2 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_666374.1 - 1.8e-06 28.1 0.3 1.8e-06 28.1 0.3 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain TFIIF_alpha PF05793.12 XP_666374.1 - 0.00077 18.2 23.8 0.0012 17.6 23.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2828 PF11443.8 XP_666374.1 - 0.026 12.6 13.0 0.042 11.9 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 XP_666374.1 - 0.21 11.6 14.7 0.46 10.5 14.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.11 XP_666374.1 - 0.28 11.1 8.9 0.52 10.3 8.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDHD PF02862.17 XP_666374.1 - 0.82 9.8 11.1 0.32 11.1 8.2 1.8 2 0 0 2 2 2 0 DDHD domain GAGA_bind PF06217.12 XP_666374.1 - 1.9 8.7 11.7 3.6 7.8 11.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family XAP5 PF04921.14 XP_666374.1 - 2.1 8.1 21.2 4.2 7.1 21.2 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 XP_666374.1 - 2.2 6.5 24.6 0.26 9.6 20.4 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF4045 PF13254.6 XP_666374.1 - 7.3 6.1 19.4 12 5.4 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 XP_666374.1 - 9.9 6.2 27.1 17 5.5 27.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated EF-hand_11 PF08976.11 XP_666376.1 - 0.036 15.0 0.1 1.2 10.1 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain PI3_PI4_kinase PF00454.27 XP_666377.1 - 3.7e-21 76.1 0.8 1.1e-20 74.5 0.8 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 XP_666377.1 - 4e-12 46.0 7.2 1.1e-09 38.0 0.9 3.6 3 1 0 3 3 3 2 FAT domain FATC PF02260.20 XP_666377.1 - 0.00011 22.0 0.1 0.00044 20.0 0.0 2.1 2 0 0 2 2 2 1 FATC domain MOZART1 PF12554.8 XP_666377.1 - 0.069 12.9 0.2 0.57 10.0 0.1 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Torus PF16131.5 XP_666378.1 - 7.5e-06 26.6 8.1 0.0015 19.2 0.2 2.4 1 1 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 XP_666378.1 - 2.7e-05 24.1 24.1 8.3e-05 22.5 3.0 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH PF00642.24 XP_666378.1 - 7.3e-05 22.6 2.6 7.3e-05 22.6 2.6 4.0 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 XP_666378.1 - 7.4e-05 22.5 15.8 0.0029 17.4 1.2 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 XP_666378.1 - 0.2 12.2 18.1 0.88 10.1 1.9 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 XP_666378.1 - 2 8.7 12.8 7.4 6.8 1.7 2.7 1 1 1 2 2 2 0 Zinc-finger containing family Stk19 PF10494.9 XP_666379.1 - 0.17 11.6 4.6 0.3 10.7 4.5 1.6 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 zf-primase PF09329.11 XP_666380.1 - 8.2e-08 31.9 0.9 8.2e-08 31.9 0.9 2.1 2 0 0 2 2 2 1 Primase zinc finger zf-C3Hc3H PF13891.6 XP_666380.1 - 0.017 15.5 0.1 0.075 13.4 0.1 2.2 1 0 0 1 1 1 0 Potential DNA-binding domain Ribosomal_L32p PF01783.23 XP_666380.1 - 0.12 12.7 0.2 24 5.3 0.0 3.0 2 0 0 2 2 2 0 Ribosomal L32p protein family RRM_1 PF00076.22 XP_666381.1 - 5.9e-13 48.4 0.0 9.4e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GIY-YIG PF01541.24 XP_666384.1 - 0.031 14.5 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain Phycobilisome PF00502.19 XP_666384.1 - 0.039 13.9 0.9 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Phycobilisome protein SWIRM PF04433.17 XP_666385.1 - 5.3e-31 106.8 2.1 5.3e-31 106.8 2.1 2.9 2 1 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 XP_666385.1 - 3.7e-13 49.2 5.7 8.7e-13 48.0 5.7 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 XP_666385.1 - 7.6e-10 38.9 0.0 2.4e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 XP_666385.1 - 1.3e-09 38.1 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_II_R PF09551.10 XP_666385.1 - 2.4 8.6 5.7 0.57 10.6 0.7 2.6 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) zf-RING_UBOX PF13445.6 XP_666386.1 - 4e-07 30.0 7.2 1.1e-06 28.6 7.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_666386.1 - 2.2e-06 27.5 5.5 7.7e-06 25.8 5.6 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 XP_666386.1 - 9.4e-06 25.4 7.8 2.1e-05 24.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_666386.1 - 5.7e-05 23.4 6.9 0.00013 22.2 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 XP_666386.1 - 7.4e-05 22.5 5.1 0.00016 21.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 XP_666386.1 - 0.00039 20.5 8.5 0.00099 19.2 8.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 XP_666386.1 - 0.0013 18.5 9.0 0.011 15.6 9.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3016 PF11454.8 XP_666386.1 - 0.074 12.8 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) Tma16 PF11176.8 XP_666386.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 zf-MIZ PF02891.20 XP_666386.1 - 0.92 9.3 5.8 2.3 8.0 5.8 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 XP_666386.1 - 1.3 8.9 10.7 55 3.7 0.3 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ArfGap PF01412.18 XP_666387.1 - 1.1e-38 131.8 0.7 1.1e-38 131.8 0.7 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf ABC2_membrane_3 PF12698.7 XP_666387.1 - 2.9 6.9 6.0 0.58 9.2 2.0 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein NTP_transferase PF00483.23 XP_666388.1 - 9.2e-43 146.6 0.0 1.2e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 XP_666388.1 - 3.2e-09 36.2 16.6 4e-08 32.7 3.5 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 XP_666388.1 - 1.1e-06 29.1 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 XP_666388.1 - 0.0034 16.4 3.6 0.08 11.9 2.7 2.8 2 1 0 2 2 2 1 L-fucokinase DUF4954 PF16314.5 XP_666388.1 - 0.0051 15.0 1.5 0.008 14.4 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 XP_666388.1 - 0.011 15.5 4.2 0.011 15.5 4.2 3.0 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Thioredoxin_6 PF13848.6 XP_666389.1 - 2.4e-07 30.9 0.6 0.097 12.6 0.1 3.4 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 XP_666389.1 - 0.00045 20.2 0.1 0.23 11.5 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin UBM PF14377.6 XP_666390.1 - 0.0001 21.6 5.2 0.0019 17.6 1.1 3.8 3 0 0 3 3 3 2 Ubiquitin binding region Methyltrn_RNA_3 PF02598.17 XP_666391.1 - 3.4e-95 318.9 0.0 4.1e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 XP_666391.1 - 0.0012 19.1 0.0 0.024 14.8 0.0 2.6 3 0 0 3 3 3 1 SpoU rRNA Methylase family LSM PF01423.22 XP_666392.1 - 7.2e-18 64.0 0.4 1e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 XP_666392.1 - 0.00014 21.9 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 XP_666392.1 - 0.0069 16.5 0.0 0.0098 16.0 0.0 1.3 1 1 0 1 1 1 1 Scd6-like Sm domain Snf7 PF03357.21 XP_666393.1 - 8.5e-18 64.5 12.6 1.1e-17 64.2 12.6 1.2 1 0 0 1 1 1 1 Snf7 DUF5082 PF16888.5 XP_666393.1 - 0.0011 19.2 3.8 0.47 10.7 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) IFT57 PF10498.9 XP_666393.1 - 0.039 12.9 8.0 0.064 12.2 8.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SPX PF03105.19 XP_666393.1 - 0.13 12.1 3.6 0.18 11.7 3.1 1.4 1 1 0 1 1 1 0 SPX domain YlqD PF11068.8 XP_666393.1 - 0.3 11.5 7.7 0.18 12.1 5.2 1.8 1 1 1 2 2 2 0 YlqD protein SOAR PF16533.5 XP_666393.1 - 0.35 10.8 9.8 1 9.4 0.6 2.7 2 1 1 3 3 3 0 STIM1 Orai1-activating region DUF3585 PF12130.8 XP_666393.1 - 0.4 10.8 11.2 0.38 10.9 6.5 2.2 1 1 1 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Spc24 PF08286.11 XP_666393.1 - 0.85 9.9 7.1 1.9 8.8 6.6 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 K-box PF01486.17 XP_666393.1 - 1.5 9.1 10.8 0.38 10.9 1.4 3.0 2 1 0 2 2 2 0 K-box region GPS2_interact PF15784.5 XP_666393.1 - 2.1 8.8 7.3 3 8.3 2.7 2.6 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Fzo_mitofusin PF04799.13 XP_666393.1 - 6.1 6.4 7.6 1.8 8.1 1.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region APG6_N PF17675.1 XP_666393.1 - 8.4 6.9 12.2 6.5 7.3 7.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1945 PF09178.10 XP_666395.1 - 0.17 12.1 0.6 0.37 11.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) GTP_EFTU PF00009.27 XP_666396.1 - 1.4e-52 178.1 0.0 2.1e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 XP_666396.1 - 8.6e-41 138.8 0.1 2.6e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 XP_666396.1 - 2.1e-16 60.1 0.5 9.7e-16 57.9 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 XP_666396.1 - 9.4e-05 22.5 0.0 0.0035 17.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 XP_666396.1 - 0.00096 19.0 0.4 0.0033 17.3 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FlpD PF02662.16 XP_666396.1 - 0.024 14.6 0.1 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit G-alpha PF00503.20 XP_666396.1 - 0.19 10.8 0.2 0.88 8.7 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Glutaredoxin PF00462.24 XP_666398.1 - 1.2e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin ZinT PF09223.11 XP_666398.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment EFG_C PF00679.24 XP_666399.1 - 1.8e-15 56.7 0.0 6.2e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 XP_666399.1 - 1.2e-06 28.5 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 XP_666399.1 - 0.00024 20.9 0.0 0.00077 19.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 XP_666399.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF4200 PF13863.6 XP_666400.1 - 0.25 11.8 20.2 0.034 14.5 15.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) JAKMIP_CC3 PF16034.5 XP_666400.1 - 0.99 9.3 25.7 0.13 12.2 2.7 2.8 2 1 0 2 2 2 0 JAKMIP CC3 domain DUF1664 PF07889.12 XP_666400.1 - 1.7 8.7 10.8 0.035 14.1 2.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 XP_666400.1 - 3 7.9 20.9 0.24 11.5 15.4 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DDE_Tnp_1 PF01609.21 XP_666400.1 - 3.8 7.1 8.4 0.26 10.9 2.5 2.0 2 0 0 2 2 2 0 Transposase DDE domain SlyX PF04102.12 XP_666400.1 - 3.9 8.2 16.3 2.6 8.7 0.2 4.4 2 1 2 4 4 4 0 SlyX DnaJ PF00226.31 XP_666401.1 - 2.9e-15 56.1 0.0 5.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2732 PF10809.8 XP_666401.1 - 0.03 14.2 1.1 4.2 7.3 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2732) Multi-haem_cyto PF13447.6 XP_666401.1 - 0.049 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH RNA_pol_Rpb8 PF03870.15 XP_666402.1 - 1.9e-40 138.3 0.0 2.1e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 XP_666402.1 - 6.5e-05 23.0 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G LSM PF01423.22 XP_666403.1 - 6.7e-16 57.7 0.0 8.7e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 XP_666403.1 - 0.0012 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain TAXi_N PF14543.6 XP_666404.1 - 1.6e-13 51.3 0.2 1e-11 45.4 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 XP_666404.1 - 1.4e-12 47.6 0.2 7.1e-12 45.4 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 XP_666404.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal WD40 PF00400.32 XP_666405.1 - 2.9e-26 91.2 25.6 4.4e-08 33.7 0.8 7.7 6 1 2 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_666405.1 - 3e-13 49.9 0.7 0.076 13.3 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DEK_C PF08766.11 XP_666406.1 - 6.8e-11 41.9 1.8 8.5e-11 41.6 0.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain ATP-cone PF03477.16 XP_666406.1 - 0.19 12.3 1.5 0.35 11.5 0.4 2.0 1 1 1 2 2 2 0 ATP cone domain CTK3 PF12243.8 XP_666407.1 - 0.0086 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 FlaF PF07309.11 XP_666407.1 - 0.062 13.3 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 Flagellar protein FlaF Na_H_Exchanger PF00999.21 XP_666409.1 - 0.00016 20.6 4.2 0.00022 20.2 4.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zinc_ribbon_16 PF17034.5 XP_666410.1 - 5.6e-15 55.7 15.5 5.6e-15 55.7 15.5 1.7 2 0 0 2 2 2 1 Zinc-ribbon like family RabGAP-TBC PF00566.18 XP_666412.1 - 1.4e-23 83.7 8.3 1.8e-22 80.1 8.3 2.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SYF2 PF08231.12 XP_666413.1 - 0.031 14.7 0.5 0.087 13.2 0.5 1.7 1 0 0 1 1 1 0 SYF2 splicing factor Alg6_Alg8 PF03155.15 XP_666414.1 - 9e-37 127.2 37.2 1.1e-36 126.9 37.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ATPase_2 PF01637.18 XP_666415.1 - 0.012 15.6 0.5 0.026 14.4 0.5 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Regnase_1_C PF18561.1 XP_666415.1 - 0.17 11.6 0.1 0.38 10.5 0.1 1.5 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Cytochrom_c3_2 PF14537.6 XP_666415.1 - 3.5 8.1 5.6 12 6.4 2.3 2.3 2 0 0 2 2 2 0 Cytochrome c3 DZR PF12773.7 XP_666415.1 - 7.3 6.7 8.0 18 5.4 1.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon DUF3976 PF13121.6 XP_666416.1 - 0.08 13.1 0.5 0.22 11.7 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) DUF202 PF02656.15 XP_666416.1 - 3.5 8.1 10.1 0.36 11.3 1.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) TRIQK PF15168.6 XP_666416.1 - 7.3 6.6 8.7 11 6.0 0.4 2.9 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family PWWP PF00855.17 XP_666417.1 - 0.0074 16.7 0.1 0.51 10.8 0.0 2.6 1 1 1 2 2 2 2 PWWP domain Ras PF00071.22 XP_666418.1 - 2.2e-16 59.9 0.2 2.5e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 Ras family WD40 PF00400.32 XP_666419.1 - 1.6e-06 28.7 1.2 0.0022 18.8 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PK PF00224.21 XP_666420.1 - 2.3e-136 454.3 1.8 9e-135 449.0 0.8 2.0 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 XP_666420.1 - 1.8e-29 102.3 2.1 4.8e-29 101.0 1.9 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 XP_666420.1 - 0.0022 17.2 0.1 0.0049 16.0 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family TauE PF01925.19 XP_666421.1 - 2.7e-22 79.6 17.2 1.7e-12 47.5 4.2 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF1356 PF07092.12 XP_666421.1 - 0.13 11.6 7.2 0.2 10.9 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1356) DUF2628 PF10947.8 XP_666421.1 - 2.6 8.5 7.9 6.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) FYRC PF05965.14 XP_666424.1 - 0.051 13.7 0.0 27 5.0 0.0 3.1 2 0 0 2 2 2 0 F/Y rich C-terminus ZapD PF07072.11 XP_666425.1 - 0.046 13.5 0.6 0.34 10.6 0.1 2.6 3 1 1 4 4 4 0 Cell division protein Med9 PF07544.13 XP_666425.1 - 1.3 9.2 4.5 0.58 10.3 0.7 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TrbM PF07424.11 XP_666426.1 - 0.022 14.7 0.5 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 TrbM Mito_fiss_reg PF05308.11 XP_666427.1 - 8.4 6.4 17.3 9.3 6.2 17.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Sigma70_ner PF04546.13 XP_666428.1 - 0.0015 18.5 6.7 0.0015 18.5 6.7 2.4 3 0 0 3 3 3 1 Sigma-70, non-essential region Tropomyosin_1 PF12718.7 XP_666428.1 - 0.024 14.8 9.7 0.03 14.5 0.4 2.3 2 0 0 2 2 2 0 Tropomyosin like PLU-1 PF08429.11 XP_666428.1 - 0.041 13.0 3.0 1.4 8.0 0.2 2.3 2 0 0 2 2 2 0 PLU-1-like protein Prefoldin_2 PF01920.20 XP_666428.1 - 0.078 12.9 14.2 0.073 13.0 2.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit Patched PF02460.18 XP_666429.1 - 1.1e-14 53.6 6.8 1.2e-14 53.5 6.8 1.0 1 0 0 1 1 1 1 Patched family RSN1_TM PF13967.6 XP_666429.1 - 0.067 13.0 1.4 0.074 12.8 1.4 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport MttA_Hcf106 PF02416.16 XP_666429.1 - 0.33 10.3 0.9 0.54 9.6 0.9 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family Patched PF02460.18 XP_666430.1 - 7.9e-17 60.6 6.2 8.3e-17 60.6 6.2 1.0 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 XP_666430.1 - 0.0015 16.3 4.3 0.0017 16.1 4.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 XP_666430.1 - 0.12 11.7 5.0 0.15 11.4 5.0 1.1 1 0 0 1 1 1 0 Protein export membrane protein Patched PF02460.18 XP_666431.1 - 5.3e-32 110.8 10.5 7.1e-30 103.8 1.7 2.3 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 XP_666431.1 - 2.4e-29 102.2 3.1 4.1e-29 101.4 3.1 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Rab5ip PF07019.12 XP_666431.1 - 0.063 13.9 4.5 0.17 12.5 0.4 2.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) TGT PF01702.18 XP_666433.1 - 5.7e-142 473.0 0.0 7.2e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Helicase_C_2 PF13307.6 XP_666434.1 - 1.5e-42 145.7 0.3 6e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 XP_666434.1 - 2.9e-37 128.0 9.6 5.1e-15 55.5 1.6 4.7 3 1 1 4 4 4 3 DEAD_2 HBB PF06777.11 XP_666434.1 - 1.7e-26 93.1 0.7 2.1e-20 73.3 0.1 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 XP_666434.1 - 1.4e-11 44.7 0.0 7.8e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 XP_666434.1 - 0.027 13.9 0.0 0.89 9.0 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein MIF4G PF02854.19 XP_666434.1 - 0.031 13.9 0.2 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 MIF4G domain Flavi_DEAD PF07652.14 XP_666434.1 - 0.1 12.5 0.1 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Flavivirus DEAD domain SNF2_N PF00176.23 XP_666434.1 - 0.12 11.0 0.1 1.3 7.6 0.1 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.6 XP_666434.1 - 0.17 12.2 0.4 1.2 9.5 0.4 2.5 1 1 0 1 1 1 0 AAA domain Metallophos PF00149.28 XP_666435.1 - 1.2e-35 123.9 0.4 1.9e-35 123.3 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 XP_666435.1 - 0.019 15.4 0.4 0.046 14.2 0.4 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 XP_666435.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Plus-3 PF03126.18 XP_666436.1 - 1.8e-09 38.1 1.2 1.3e-08 35.4 0.0 3.0 3 0 0 3 3 3 1 Plus-3 domain DUF4041 PF13250.6 XP_666436.1 - 0.024 14.5 3.2 0.073 13.0 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) ECM11 PF15463.6 XP_666437.1 - 1.4 9.5 9.0 2.8 8.5 9.0 1.4 1 0 0 1 1 1 0 Extracellular mutant protein 11 NPV_P10 PF05531.12 XP_666438.1 - 0.0026 18.2 1.5 0.0038 17.7 1.5 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein RP-C_C PF11800.8 XP_666438.1 - 0.34 11.0 7.0 0.39 10.8 7.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region CHD5 PF04420.14 XP_666438.1 - 0.73 9.7 3.8 1.2 9.0 3.8 1.5 1 1 0 1 1 1 0 CHD5-like protein Ribosomal_S7e PF01251.18 XP_666439.1 - 9.2e-60 201.5 0.1 1e-59 201.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FANCD2OS PF15124.6 XP_666439.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 FANCD2 opposite strand protein p25-alpha PF05517.12 XP_666440.1 - 1.6e-10 41.3 0.9 2.4e-10 40.8 0.9 1.3 1 0 0 1 1 1 1 p25-alpha Nse4_C PF08743.10 XP_666441.1 - 0.0013 19.0 1.8 0.0023 18.2 0.1 2.3 2 0 0 2 2 2 1 Nse4 C-terminal COesterase PF00135.28 XP_666442.1 - 2.1e-59 201.8 2.6 7.1e-59 200.0 2.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 XP_666442.1 - 8.8e-11 42.1 0.0 5.7e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 XP_666442.1 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 XP_666442.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family CENP-F_leu_zip PF10473.9 XP_666442.1 - 1.2 9.2 5.6 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNase_J_C PF17770.1 XP_666443.1 - 0.016 16.3 0.1 0.22 12.6 0.0 2.9 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain WH2 PF02205.20 XP_666443.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 WH2 motif Phage_fiber_2 PF03406.13 XP_666444.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail fibre repeat Arf PF00025.21 XP_666445.1 - 3.4e-11 42.9 0.0 4.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 XP_666445.1 - 0.0031 17.0 0.1 0.0056 16.1 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit T2SSE PF00437.20 XP_666445.1 - 0.0055 15.8 0.2 0.0074 15.4 0.2 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 XP_666445.1 - 0.0073 16.0 0.3 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 XP_666445.1 - 0.0076 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 XP_666445.1 - 0.03 14.6 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 XP_666445.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_18 PF13238.6 XP_666445.1 - 0.1 13.1 0.5 0.34 11.5 0.4 2.0 2 1 0 2 2 1 0 AAA domain cobW PF02492.19 XP_666445.1 - 0.12 12.0 0.2 0.25 10.9 0.1 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 XP_666445.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 XP_666445.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 XP_666445.1 - 0.2 11.4 0.0 2.7 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 XP_666445.1 - 0.27 11.6 0.1 0.47 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 XP_666445.1 - 0.28 11.3 0.3 0.6 10.3 0.3 1.5 2 0 0 2 2 2 0 AAA domain S10_plectin PF03501.15 XP_666446.1 - 1.6e-38 130.7 0.2 1.9e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 Plectin/S10 domain AAA PF00004.29 XP_666447.1 - 1e-37 129.5 0.0 2.3e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 XP_666447.1 - 1.7e-07 31.1 0.0 6.5e-07 29.2 0.0 2.0 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 XP_666447.1 - 9.7e-07 28.5 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 XP_666447.1 - 1e-05 25.8 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 XP_666447.1 - 8e-05 22.7 0.4 0.0064 16.5 0.2 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 XP_666447.1 - 0.00019 21.7 0.2 0.0015 18.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 XP_666447.1 - 0.002 18.1 0.3 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 XP_666447.1 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 XP_666447.1 - 0.003 17.9 0.0 0.0092 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 XP_666447.1 - 0.0032 17.9 0.1 0.023 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 XP_666447.1 - 0.0038 16.6 0.1 0.0072 15.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 XP_666447.1 - 0.0071 16.9 0.0 0.026 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 XP_666447.1 - 0.0082 15.7 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 XP_666447.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 XP_666447.1 - 0.021 14.6 0.3 0.092 12.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 XP_666447.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 XP_666447.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 XP_666447.1 - 0.081 12.1 0.0 6.2 5.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.23 XP_666447.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_33 PF13671.6 XP_666447.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cofilin_ADF PF00241.20 XP_666448.1 - 1.4e-27 95.9 0.1 1.6e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Trypan_PARP PF05887.11 XP_666450.1 - 0.15 12.0 15.3 0.25 11.3 15.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L23 PF00276.20 XP_666451.1 - 1.2e-12 48.0 5.8 4.8e-12 46.1 5.8 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 WWE PF02825.20 XP_666452.1 - 4.9e-10 39.8 0.4 1.4e-09 38.4 0.4 1.9 1 0 0 1 1 1 1 WWE domain DNA_pol_lambd_f PF10391.9 XP_666454.1 - 0.096 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Gar1 PF04410.14 XP_666456.1 - 1.5e-15 57.3 0.0 1.5e-15 57.3 0.0 2.9 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region Actin PF00022.19 XP_666457.1 - 3.4e-29 101.7 0.0 5.5e-27 94.4 0.0 2.3 1 1 0 1 1 1 1 Actin DUF4866 PF16160.5 XP_666457.1 - 0.011 15.1 0.4 0.017 14.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Sec1 PF00995.23 XP_666458.1 - 1.8e-85 288.3 14.4 2.1e-85 288.1 14.4 1.0 1 0 0 1 1 1 1 Sec1 family PCI PF01399.27 XP_666461.1 - 8.7e-10 39.1 0.3 4.5e-09 36.8 0.3 2.2 2 1 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 XP_666461.1 - 1.8e-05 24.4 0.3 4.2e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix LZ3wCH PF18517.1 XP_666461.1 - 0.25 11.5 2.2 1 9.5 0.0 3.1 3 0 0 3 3 3 0 Leucine zipper with capping helix domain TSP_1 PF00090.19 XP_666463.1 - 1.1e-20 73.5 107.4 3.8e-09 36.6 6.4 8.4 9 1 0 9 9 9 6 Thrombospondin type 1 domain PAN_4 PF14295.6 XP_666463.1 - 0.0011 18.8 1.5 0.0011 18.8 1.5 6.5 7 2 0 7 7 7 1 PAN domain TSP_1 PF00090.19 XP_666464.1 - 4.3e-08 33.2 54.6 5.3e-06 26.5 4.7 6.2 5 2 0 5 5 5 4 Thrombospondin type 1 domain PAN_1 PF00024.26 XP_666464.1 - 4.2e-07 29.8 8.4 7e-05 22.7 1.6 3.9 4 1 1 5 5 5 2 PAN domain PAN_4 PF14295.6 XP_666464.1 - 0.0012 18.7 1.5 0.0012 18.7 1.5 4.4 4 0 0 4 4 4 1 PAN domain AP2 PF00847.20 XP_666465.1 - 1.3e-11 44.6 3.7 2.4e-11 43.7 3.7 1.4 1 0 0 1 1 1 1 AP2 domain Tho2 PF11262.8 XP_666466.1 - 0.0043 16.3 1.8 0.0058 15.9 0.0 1.9 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 UNC-93 PF05978.16 XP_666467.1 - 0.012 15.4 8.0 0.012 15.4 8.0 1.8 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 XP_666467.1 - 0.057 12.3 16.5 0.034 13.1 14.2 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily NAD4L PF06235.11 XP_666467.1 - 2.2 8.3 11.8 1.4 8.9 0.6 2.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) TcpE PF12648.7 XP_666468.1 - 0.0075 16.8 0.3 0.0075 16.8 0.3 2.6 3 0 0 3 3 3 1 TcpE family 14-3-3 PF00244.20 XP_666469.1 - 5.1e-14 52.3 2.9 5.8e-14 52.1 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein NAS PF03059.16 XP_666469.1 - 0.012 15.0 0.3 0.016 14.5 0.3 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Cyclin PF08613.11 XP_666471.1 - 3.7e-18 66.4 0.1 3.7e-18 66.4 0.1 2.3 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 XP_666471.1 - 0.019 14.7 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF389 PF04087.14 XP_666472.1 - 4.1e-05 23.6 8.3 0.0023 18.0 0.1 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF389) DUF2157 PF09925.9 XP_666472.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) TauE PF01925.19 XP_666472.1 - 0.03 14.0 19.1 0.02 14.5 16.6 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Ceramidase PF05875.12 XP_666472.1 - 0.033 13.6 2.7 0.027 13.9 1.0 1.5 1 1 0 1 1 1 0 Ceramidase Caa3_CtaG PF09678.10 XP_666472.1 - 0.069 12.6 1.5 0.09 12.2 0.8 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) SDF PF00375.18 XP_666472.1 - 0.11 11.5 17.1 0.21 10.6 9.5 2.5 3 0 0 3 3 3 0 Sodium:dicarboxylate symporter family LapA_dom PF06305.11 XP_666472.1 - 0.13 12.1 0.1 0.13 12.1 0.1 4.1 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF4131 PF13567.6 XP_666472.1 - 0.26 10.9 7.3 3.4 7.3 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UPF0182 PF03699.13 XP_666472.1 - 2.9 5.9 6.8 0.4 8.8 1.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0182) FTR1 PF03239.14 XP_666472.1 - 7.3 5.7 12.4 0.16 11.1 1.3 2.9 2 1 1 3 3 3 0 Iron permease FTR1 family TMEM220 PF15071.6 XP_666473.1 - 0.032 15.0 1.7 0.07 13.9 1.5 1.7 1 1 0 1 1 1 0 Transmembrane family 220, helix DUF2663 PF10864.8 XP_666473.1 - 2.5 8.5 7.1 0.23 11.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) CDT1_C PF16679.5 XP_666475.1 - 0.015 15.7 0.6 0.033 14.6 0.6 1.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF1572 PF07609.11 XP_666475.1 - 0.035 13.9 0.2 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Myb_DNA-bind_7 PF15963.5 XP_666475.1 - 0.21 11.5 3.2 0.37 10.7 0.5 2.4 2 0 0 2 2 2 0 Myb DNA-binding like DUF3452 PF11934.8 XP_666475.1 - 4 7.0 8.2 1.5 8.4 0.6 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3452) AdoHcyase PF05221.17 XP_666477.1 - 4.5e-119 397.0 0.1 5.3e-119 396.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 XP_666477.1 - 4.9e-70 234.8 2.2 7.9e-70 234.1 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 XP_666477.1 - 2.3e-10 40.1 0.1 4.4e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 XP_666477.1 - 1.5e-06 27.9 0.3 2.6e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 XP_666477.1 - 3.8e-06 27.0 0.1 1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 XP_666477.1 - 0.00017 21.8 1.3 0.0014 18.9 1.3 2.2 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 XP_666477.1 - 0.00029 21.2 0.1 0.00087 19.7 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 XP_666477.1 - 0.002 17.5 1.3 0.008 15.5 1.3 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 XP_666477.1 - 0.003 16.9 0.7 0.0077 15.5 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 XP_666477.1 - 0.0066 17.0 0.3 0.014 16.0 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent HetR_C PF18460.1 XP_666478.1 - 0.084 12.8 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF676 PF05057.14 XP_666480.1 - 1.2e-41 142.7 0.0 2.9e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 XP_666480.1 - 8.7e-18 64.6 1.0 4.1e-17 62.5 1.0 2.3 1 0 0 1 1 1 1 Protein FAM135 PGAP1 PF07819.13 XP_666480.1 - 0.00018 21.3 0.2 0.0093 15.7 0.2 2.3 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 XP_666480.1 - 0.00057 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 XP_666480.1 - 0.04 14.5 0.0 0.066 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_A21 PF03566.13 XP_666480.1 - 0.14 10.4 0.0 0.25 9.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family A21 Transformer PF06495.11 XP_666481.1 - 0.78 9.8 35.6 2.6 8.1 35.6 1.8 1 0 0 1 1 1 0 Fruit fly transformer protein HNF-1_N PF04814.13 XP_666482.1 - 0.054 14.1 0.6 0.054 14.1 0.6 2.2 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pkinase PF00069.25 XP_666483.1 - 1.9e-31 109.4 0.4 1.9e-14 53.7 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666483.1 - 2e-10 40.4 0.0 1.9e-05 24.1 0.0 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 XP_666483.1 - 8.8e-05 21.9 0.2 0.44 9.8 0.0 3.9 4 0 0 4 4 4 1 Kinase-like FTA2 PF13095.6 XP_666483.1 - 0.0081 15.8 0.2 0.53 9.9 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Cwf_Cwc_15 PF04889.12 XP_666483.1 - 0.2 11.4 7.3 0.024 14.4 2.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Syntaxin PF00804.25 XP_666485.1 - 2.5e-22 79.5 15.6 3.2e-22 79.2 15.6 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 XP_666485.1 - 1.2e-12 47.6 0.7 2.7e-12 46.5 0.7 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 XP_666485.1 - 6.9e-05 23.2 18.1 0.0036 17.6 8.4 2.4 2 0 0 2 2 2 2 Syntaxin-like protein CDT1 PF08839.11 XP_666485.1 - 0.0065 16.8 4.4 0.084 13.2 0.3 2.4 1 1 0 2 2 2 1 DNA replication factor CDT1 like Gemini_BL1 PF00845.19 XP_666485.1 - 0.013 15.1 1.2 0.017 14.7 1.2 1.3 1 0 0 1 1 1 0 Geminivirus BL1 movement protein CTK3 PF12243.8 XP_666485.1 - 0.026 14.5 1.2 0.071 13.1 0.2 2.1 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 Orf78 PF06024.12 XP_666485.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.5 3 0 0 3 3 3 0 Orf78 (ac78) DUF1676 PF07898.13 XP_666485.1 - 0.11 12.5 7.8 1.4 8.9 7.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2116 PF09889.9 XP_666485.1 - 0.14 12.1 2.1 0.41 10.7 2.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2203 PF09969.9 XP_666485.1 - 5.8 7.7 12.2 12 6.6 3.5 3.2 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF745 PF05335.13 XP_666485.1 - 6.2 6.5 10.4 7.3 6.3 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Ribosomal_L27A PF00828.19 XP_666485.1 - 6.5 7.4 10.1 4.2 8.0 6.4 2.4 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-C2H2 PF00096.26 XP_666486.1 - 2.9e-26 90.4 49.9 1.1e-05 25.6 4.0 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 XP_666486.1 - 1.8e-22 78.1 48.7 0.00054 20.6 1.1 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 XP_666486.1 - 1.3e-10 41.2 54.0 1.4e-05 25.3 2.5 8.8 9 1 0 9 9 9 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 XP_666486.1 - 5.5e-08 32.6 30.7 0.002 18.1 0.1 6.5 6 1 0 6 6 6 3 C2H2-type zinc finger FOXP-CC PF16159.5 XP_666486.1 - 1.1e-05 25.9 12.7 1.3 9.7 0.1 6.4 4 2 3 7 7 7 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 XP_666486.1 - 0.0017 18.0 44.3 0.078 12.8 1.0 6.9 7 1 0 7 7 6 4 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 XP_666486.1 - 0.003 18.3 15.4 0.037 14.7 6.4 3.8 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 XP_666486.1 - 0.0052 16.4 1.9 6 6.6 0.0 3.9 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 XP_666486.1 - 0.0069 16.5 19.3 0.67 10.1 4.9 3.7 3 1 0 3 3 3 2 Aberrant zinc-finger Ribosomal_S26e PF01283.19 XP_666486.1 - 0.015 15.7 0.3 2.5 8.6 0.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S26e PBECR3 PF18812.1 XP_666486.1 - 0.017 15.1 1.0 9.1 6.3 0.0 3.8 4 1 0 4 4 4 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf-met PF12874.7 XP_666486.1 - 0.019 15.4 28.6 0.27 11.7 0.1 7.4 8 0 0 8 8 7 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 XP_666486.1 - 0.28 10.8 0.0 0.28 10.8 0.0 5.7 4 3 1 5 5 5 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 XP_666486.1 - 0.31 11.4 25.2 3.2 8.2 0.4 7.9 8 1 1 9 9 9 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 XP_666486.1 - 1.9 8.2 20.3 2.3 7.9 0.9 4.9 1 1 4 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 XP_666486.1 - 4.7 5.6 22.1 2.9 6.3 1.5 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF629) Paf67 PF10255.9 XP_666487.1 - 1.8e-100 336.8 5.3 1.8e-100 336.8 5.3 1.4 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 XP_666487.1 - 0.0033 17.4 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Pox_E10 PF04805.12 XP_666487.1 - 1.5 8.8 8.9 3.5 7.6 2.4 3.1 3 0 0 3 3 3 0 E10-like protein conserved region zf-ZPR1 PF03367.13 XP_666488.1 - 1.2e-67 226.8 6.0 2.3e-54 183.6 0.5 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 XP_666488.1 - 0.0042 17.1 3.0 0.15 12.1 0.1 2.5 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 XP_666488.1 - 0.02 14.8 6.4 2.4 8.2 0.3 3.6 4 0 0 4 4 4 0 Transposase zinc-ribbon domain DUF3797 PF12677.7 XP_666488.1 - 0.22 11.4 4.0 2.3 8.2 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CpXC PF14353.6 XP_666488.1 - 0.71 9.9 4.9 13 5.8 0.9 3.1 2 1 0 2 2 2 0 CpXC protein DUF1610 PF07754.11 XP_666488.1 - 1.7 8.7 10.7 4.4 7.4 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-Mss51 PF13824.6 XP_666488.1 - 3.7 7.7 7.9 7.3 6.8 0.2 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_10 PF10058.9 XP_666488.1 - 6.2 6.6 9.1 3.6 7.4 0.0 3.7 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 XP_666488.1 - 6.4 7.0 9.8 39 4.5 0.1 3.7 3 1 1 4 4 4 0 Zinc ribbon domain zf-ZPR1 PF03367.13 XP_666489.1 - 7e-28 97.5 0.3 1e-27 97.0 0.3 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Methyltransf_15 PF09445.10 XP_666490.1 - 2e-24 86.1 1.5 8.6e-14 51.4 0.1 2.6 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 XP_666490.1 - 0.00057 19.6 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DUF4373 PF14297.6 XP_666490.1 - 0.019 15.8 0.2 0.051 14.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) Methyltransf_25 PF13649.6 XP_666490.1 - 0.055 14.2 0.0 0.26 12.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Steroid_dh PF02544.16 XP_666491.1 - 3.3e-32 111.6 7.8 6.5e-32 110.6 7.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 XP_666491.1 - 4.5e-05 23.1 0.0 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 XP_666491.1 - 0.0012 18.8 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain MFS_1 PF07690.16 XP_666491.1 - 0.11 11.5 7.8 0.14 11.0 7.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PalH PF08733.10 XP_666491.1 - 1.3 7.9 10.4 2.4 7.1 1.5 2.4 1 1 0 2 2 2 0 PalH/RIM21 PTS_2-RNA PF01885.16 XP_666492.1 - 1.3e-50 172.0 0.2 1.8e-50 171.5 0.2 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Pro_isomerase PF00160.21 XP_666493.1 - 1.7e-34 119.4 0.0 2.3e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 XP_666493.1 - 1.7e-15 56.6 0.2 4.7e-15 55.2 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 XP_666494.1 - 1.1e-24 86.0 0.1 1.6e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 XP_666494.1 - 1.5e-05 24.6 1.0 1.5e-05 24.6 1.0 2.2 2 1 0 2 2 2 1 Ribonuclease B OB domain PepSY_2 PF13670.6 XP_666494.1 - 0.38 10.8 1.0 0.82 9.7 0.1 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain API5 PF05918.11 XP_666494.1 - 0.49 9.1 4.0 0.64 8.8 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1633 PF07794.11 XP_666494.1 - 0.54 8.4 3.3 0.58 8.3 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF5320 PF17253.2 XP_666494.1 - 0.55 11.3 11.1 0.97 10.5 10.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) PNTB PF02233.16 XP_666495.1 - 5.2e-144 480.6 9.5 5.2e-144 480.6 9.5 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 XP_666495.1 - 1.5e-67 227.1 3.5 3.2e-67 226.0 3.5 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 XP_666495.1 - 7.5e-44 149.3 0.1 1.8e-43 148.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 XP_666495.1 - 2.7e-30 104.6 5.9 2.7e-30 104.6 5.9 3.8 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 XP_666495.1 - 1.4e-07 31.0 0.7 0.016 14.6 0.1 3.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 XP_666495.1 - 0.0009 18.6 0.2 0.0019 17.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 XP_666495.1 - 0.002 18.1 0.1 0.0081 16.1 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 XP_666495.1 - 0.011 15.4 0.4 0.58 9.9 0.1 3.3 2 2 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_2 PF03446.15 XP_666495.1 - 0.035 14.3 2.8 0.083 13.1 0.4 2.9 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 XP_666495.1 - 0.071 12.2 0.3 0.12 11.4 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 XP_666495.1 - 0.15 12.7 0.2 0.97 10.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SR-25 PF10500.9 XP_666495.1 - 2.2 7.8 7.7 3.8 7.0 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AT_hook PF02178.19 XP_666496.1 - 0.081 12.8 0.9 0.21 11.6 0.9 1.8 1 0 0 1 1 1 0 AT hook motif NOPS PF08075.11 XP_666497.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 NOPS (NUC059) domain IRK_C PF17655.1 XP_666498.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 XP_666498.1 - 2.5e-06 27.4 9.5 1.1e-05 25.3 9.5 1.9 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 XP_666498.1 - 1.2 9.1 11.5 3.3 7.7 11.4 1.8 1 1 1 2 2 2 0 Ion channel Cpn60_TCP1 PF00118.24 XP_666500.1 - 1.1e-147 492.6 3.0 1.3e-147 492.4 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prolamin_like PF05617.11 XP_666500.1 - 0.41 10.9 1.8 0.67 10.2 0.3 2.0 2 0 0 2 2 2 0 Prolamin-like Nuc_sug_transp PF04142.15 XP_666501.1 - 3.2e-102 341.9 24.7 3.8e-102 341.7 24.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 XP_666501.1 - 4e-05 23.8 34.0 0.00042 20.5 7.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 XP_666501.1 - 4.2e-05 22.9 13.3 0.00013 21.3 11.2 2.4 1 1 0 1 1 1 1 UAA transporter family RED_C PF07807.11 XP_666501.1 - 0.15 12.5 1.0 0.23 11.9 1.0 1.2 1 0 0 1 1 1 0 RED-like protein C-terminal region TMEM234 PF10639.9 XP_666501.1 - 5 7.2 16.9 1.2 9.2 1.1 3.2 2 1 0 3 3 3 0 Putative transmembrane family 234 Got1 PF04178.12 XP_666502.1 - 7.2e-11 42.5 15.0 8.9e-11 42.2 15.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 XP_666502.1 - 0.15 12.4 17.9 0.29 11.5 10.2 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF3119 PF11317.8 XP_666502.1 - 2.7 8.3 8.6 0.36 11.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3119) DUF3185 PF11381.8 XP_666502.1 - 6.5 6.8 12.6 25 4.9 3.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) NPL PF17800.1 XP_666503.1 - 1.9e-14 54.1 0.0 1.9e-14 54.1 0.0 3.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain NAD_Gly3P_dh_N PF01210.23 XP_666504.1 - 8.5e-43 146.0 0.0 1.2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 XP_666504.1 - 1.2e-31 110.0 0.0 1.8e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus YEATS PF03366.16 XP_666505.1 - 5.5e-30 103.2 0.1 1.7e-29 101.6 0.1 1.9 1 0 0 1 1 1 1 YEATS family UME PF08064.13 XP_666505.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Prefoldin_2 PF01920.20 XP_666505.1 - 1 9.4 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Syja_N PF02383.18 XP_666506.1 - 3.1e-61 207.4 0.0 8.7e-61 206.0 0.0 1.8 1 1 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 XP_666506.1 - 0.00033 20.3 0.0 0.00091 18.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4806 PF16064.5 XP_666506.1 - 5.1 7.5 7.5 52 4.2 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) DUF4973 PF16343.5 XP_666507.1 - 0.053 13.6 0.5 0.089 12.8 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4973) FKBP_N_2 PF18023.1 XP_666507.1 - 0.054 13.6 0.2 0.063 13.4 0.2 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Na_Ca_ex PF01699.24 XP_666509.1 - 8e-34 116.8 49.5 8.4e-21 74.5 15.3 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein RRM_1 PF00076.22 XP_666511.1 - 3.2e-13 49.3 2.6 1.7e-10 40.5 0.1 4.2 3 2 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_666511.1 - 0.00092 19.3 0.1 0.037 14.1 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif BRAP2 PF07576.12 XP_666511.1 - 0.0075 16.5 0.1 0.027 14.7 0.1 2.0 2 0 0 2 2 2 1 BRCA1-associated protein 2 DNA_pol_B PF00136.21 XP_666513.1 - 1.1e-71 242.0 0.1 1.4e-71 241.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 XP_666513.1 - 2.3e-07 30.8 1.1 4.9e-07 29.7 1.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger WEMBL PF05701.11 XP_666514.1 - 0.00048 19.0 6.4 0.00074 18.3 6.4 1.2 1 1 0 1 1 1 1 Weak chloroplast movement under blue light HIP1_clath_bdg PF16515.5 XP_666514.1 - 0.00072 20.1 2.6 0.0021 18.6 0.1 2.3 2 1 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5089 PF17002.5 XP_666514.1 - 0.01 15.7 4.0 0.032 14.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) MHC_II_beta PF00969.19 XP_666514.1 - 0.012 15.7 1.4 0.11 12.6 0.2 2.7 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain V-SNARE_C PF12352.8 XP_666514.1 - 0.012 15.9 1.8 0.021 15.1 0.4 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 XP_666514.1 - 0.028 15.0 6.1 5.8 7.5 6.1 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Paramyx_P_V_C PF03210.13 XP_666514.1 - 0.033 14.0 1.0 0.066 13.0 0.3 1.8 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Tweety PF04906.13 XP_666514.1 - 0.047 12.4 4.1 0.036 12.7 2.2 1.7 1 1 1 2 2 2 0 Tweety ABC2_membrane_3 PF12698.7 XP_666514.1 - 0.21 10.6 2.8 0.3 10.1 2.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein FlaC_arch PF05377.11 XP_666514.1 - 0.22 11.9 0.5 0.22 11.9 0.5 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MIEAP PF16026.5 XP_666514.1 - 0.69 10.1 4.4 0.66 10.2 0.7 2.0 1 1 1 2 2 2 0 Mitochondria-eating protein Sec20 PF03908.13 XP_666514.1 - 0.73 9.8 8.5 0.09 12.7 1.7 2.7 1 1 3 4 4 4 0 Sec20 Pkinase PF00069.25 XP_666515.1 - 6.8e-31 107.6 0.0 1.7e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666515.1 - 2.2e-30 105.8 0.0 3.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DBR1 PF05011.13 XP_666516.1 - 0.019 15.4 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Aa_trans PF01490.18 XP_666518.1 - 4e-41 141.1 32.7 6.1e-41 140.5 32.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PrgI PF12666.7 XP_666518.1 - 0.33 11.7 0.1 0.33 11.7 0.1 3.9 4 1 0 4 4 4 0 PrgI family protein DUF3681 PF12442.8 XP_666518.1 - 1.3 9.6 6.6 13 6.3 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) RE_HaeIII PF09556.10 XP_666519.1 - 0.0041 16.2 0.2 0.006 15.7 0.2 1.3 1 0 0 1 1 1 1 HaeIII restriction endonuclease tRNA-synt_His PF13393.6 XP_666521.1 - 1.3e-46 159.3 0.0 1.7e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 XP_666521.1 - 1.4e-12 47.6 0.0 3.3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 XP_666521.1 - 3.6e-05 23.0 0.0 0.0013 17.9 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 XP_666521.1 - 5.5e-05 23.2 3.7 0.00012 22.1 3.7 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 XP_666521.1 - 0.00025 20.7 0.1 0.00041 19.9 0.1 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 XP_666521.1 - 0.095 12.2 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) cNMP_binding PF00027.29 XP_666522.1 - 1.1e-11 44.6 0.0 1.5e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pox_Ag35 PF03286.14 XP_666522.1 - 0.026 14.3 12.3 0.053 13.3 12.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FPL PF09758.9 XP_666522.1 - 0.15 12.0 3.7 0.068 13.2 0.9 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein NPR3 PF03666.13 XP_666522.1 - 0.23 10.2 7.0 0.37 9.5 7.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 XP_666522.1 - 2.4 6.4 6.8 3.7 5.8 6.8 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 XP_666522.1 - 8.9 5.0 5.3 13 4.4 5.3 1.1 1 0 0 1 1 1 0 Presenilin ASFV_J13L PF05568.11 XP_666524.1 - 0.091 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF1108 PF06531.11 XP_666524.1 - 0.86 9.9 5.2 0.16 12.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) DnaJ PF00226.31 XP_666525.1 - 2.4e-23 82.0 0.1 4.7e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 XP_666525.1 - 1.9e-05 24.6 0.0 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 XP_666525.1 - 0.063 13.2 0.3 0.063 13.2 0.3 2.4 3 0 0 3 3 3 0 Thioredoxin-like domain Wx5_PLAF3D7 PF09688.10 XP_666525.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) TRAPP PF04051.16 XP_666526.1 - 0.0021 17.8 0.1 0.0025 17.6 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CENP-C_C PF11699.8 XP_666527.1 - 0.00033 20.8 0.0 0.0009 19.4 0.0 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like PhoLip_ATPase_C PF16212.5 XP_666529.1 - 9.9e-55 186.0 24.8 9.9e-55 186.0 24.8 2.9 2 1 1 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 XP_666529.1 - 2.8e-18 65.4 1.1 2.8e-18 65.4 1.1 3.0 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 XP_666529.1 - 1.1e-14 55.2 0.3 1.5e-05 25.4 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 XP_666529.1 - 3.9e-05 23.2 2.7 0.00043 19.9 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 XP_666529.1 - 7.2e-05 22.6 3.2 7.7e-05 22.5 0.3 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_666529.1 - 0.0001 22.3 0.0 0.00083 19.4 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF4392 PF14336.6 XP_666529.1 - 0.087 12.3 0.1 0.68 9.3 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4392) DUF2183 PF09949.9 XP_666529.1 - 0.2 12.0 1.1 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) TMEM40 PF15817.5 XP_666529.1 - 5 6.9 7.6 12 5.7 3.6 3.2 2 0 0 2 2 2 0 Transmembrane protein 40 family TLD PF07534.16 XP_666530.1 - 1.8e-26 93.0 0.2 5e-26 91.6 0.2 1.8 1 0 0 1 1 1 1 TLD Ank_2 PF12796.7 XP_666531.1 - 0.0068 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 XP_666531.1 - 0.17 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Methyltrn_RNA_4 PF09936.9 XP_666532.1 - 0.0074 16.2 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 2 SAM-dependent RNA methyltransferase PRP38_assoc PF12871.7 XP_666533.1 - 0.015 15.9 30.9 0.015 15.9 30.9 4.5 3 1 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Tir_receptor_C PF07489.11 XP_666534.1 - 4.1 7.3 7.9 0.89 9.5 4.1 1.8 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus AAA PF00004.29 XP_666536.1 - 7.6e-42 142.9 0.0 1.4e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 XP_666536.1 - 8.6e-12 44.7 0.3 1.8e-11 43.6 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 XP_666536.1 - 7.7e-11 41.8 0.1 1.7e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 XP_666536.1 - 1.2e-07 32.2 0.0 9.3e-05 22.9 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 XP_666536.1 - 8.1e-07 29.1 0.1 1.1e-05 25.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 XP_666536.1 - 8.1e-07 29.3 0.0 5.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 XP_666536.1 - 7.6e-06 25.8 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 XP_666536.1 - 0.00015 22.0 0.1 0.015 15.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 XP_666536.1 - 0.00028 20.5 0.1 0.022 14.4 0.0 2.6 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 XP_666536.1 - 0.00031 21.3 0.3 0.0036 17.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 XP_666536.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 XP_666536.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 XP_666536.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 XP_666536.1 - 0.0017 18.1 0.0 0.0061 16.3 0.0 1.9 2 1 1 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 XP_666536.1 - 0.0023 18.3 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 XP_666536.1 - 0.0034 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_666536.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 XP_666536.1 - 0.0066 16.2 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 XP_666536.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 XP_666536.1 - 0.007 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 XP_666536.1 - 0.015 15.5 0.0 0.058 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 XP_666536.1 - 0.015 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 XP_666536.1 - 0.019 14.7 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 XP_666536.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 XP_666536.1 - 0.025 13.9 0.2 0.092 12.1 0.0 2.0 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 XP_666536.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 XP_666536.1 - 0.035 13.7 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 XP_666536.1 - 0.035 14.3 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 XP_666536.1 - 0.046 13.0 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 XP_666536.1 - 0.11 12.4 0.1 0.48 10.3 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 XP_666536.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 XP_666536.1 - 0.17 12.1 2.7 0.27 11.4 2.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2040 PF09745.9 XP_666537.1 - 3.1e-09 36.9 11.5 3.1e-09 36.9 11.5 1.9 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) CAML PF14963.6 XP_666537.1 - 7.3 6.6 9.2 0.61 10.2 4.1 1.8 2 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF2981 PF11200.8 XP_666538.1 - 0.35 10.6 4.7 0.61 9.8 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) AP2 PF00847.20 XP_666539.1 - 3.4e-11 43.2 3.3 6.9e-11 42.2 3.3 1.6 1 0 0 1 1 1 1 AP2 domain Spermine_synth PF01564.17 XP_666540.1 - 7.3e-08 32.0 0.3 5.8e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Spermine/spermidine synthase domain MTS PF05175.14 XP_666540.1 - 0.0022 17.5 0.0 0.0064 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain EntA_Immun PF08951.10 XP_666540.1 - 0.032 14.6 2.6 2.6 8.5 0.2 3.2 3 0 0 3 3 3 0 Enterocin A Immunity Methyltransf_25 PF13649.6 XP_666540.1 - 0.13 13.0 0.0 0.75 10.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain SF3A2 PF16835.5 XP_666541.1 - 5.2e-25 87.6 0.3 9.1e-25 86.9 0.3 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 XP_666541.1 - 2e-06 28.0 1.0 2e-06 28.0 1.0 2.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 XP_666541.1 - 0.039 14.3 2.3 0.7 10.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) S6PP PF05116.13 XP_666542.1 - 3e-28 99.0 0.0 1.9e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 XP_666542.1 - 2.6e-07 30.7 0.0 3.4e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chorein_N PF12624.7 XP_666545.1 - 0.15 12.2 0.6 0.26 11.4 0.6 1.4 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 Exostosin PF03016.15 XP_666548.1 - 1.1e-08 34.7 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Helicase_C PF00271.31 XP_666549.1 - 1e-32 112.8 0.1 1.6e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 XP_666549.1 - 0.16 12.1 3.4 0.24 11.5 3.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Cyclin_N PF00134.23 XP_666550.1 - 4e-06 26.6 0.1 1.4e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Rep_fac-A_C PF08646.10 XP_666551.1 - 5.7e-27 94.3 0.5 1.6e-26 92.8 0.1 1.9 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 XP_666551.1 - 5.9e-24 83.9 0.3 1.8e-21 75.9 0.0 2.5 2 0 0 2 2 2 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 XP_666551.1 - 7.9e-14 51.4 0.7 1.6e-10 40.9 0.4 3.7 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 XP_666551.1 - 4.1e-07 30.2 0.1 1.3e-05 25.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 XP_666551.1 - 0.0057 16.4 1.1 0.067 12.9 0.2 3.0 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 UPF0052 PF01933.18 XP_666551.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 DZR PF12773.7 XP_666551.1 - 0.11 12.5 0.6 0.27 11.3 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Sgf11 PF08209.11 XP_666551.1 - 0.19 11.3 2.7 3.1 7.4 0.2 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_C2H2_10 PF18414.1 XP_666551.1 - 9.5 5.9 6.3 9.1 5.9 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger Prefoldin_2 PF01920.20 XP_666552.1 - 7.4e-23 80.5 3.5 9.2e-23 80.2 3.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 XP_666552.1 - 0.00015 21.7 5.6 0.001 19.0 5.6 1.9 1 1 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 XP_666552.1 - 0.0029 18.2 0.3 3.2 8.4 0.0 2.2 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 XP_666552.1 - 0.0036 16.2 3.8 0.059 12.2 0.4 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Lectin_N PF03954.14 XP_666552.1 - 0.0036 17.0 1.0 0.0058 16.4 0.3 1.6 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain Spc24 PF08286.11 XP_666552.1 - 0.0037 17.5 3.2 0.13 12.5 1.4 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 OmpH PF03938.14 XP_666552.1 - 0.004 17.5 0.3 0.024 15.0 0.1 1.9 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF677 PF05055.12 XP_666552.1 - 0.0041 16.1 1.2 0.21 10.4 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF677) TMF_DNA_bd PF12329.8 XP_666552.1 - 0.005 16.8 11.2 0.24 11.4 1.4 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF5320 PF17253.2 XP_666552.1 - 0.0063 17.5 1.0 0.035 15.2 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5320) FlxA PF14282.6 XP_666552.1 - 0.0087 16.0 12.9 0.046 13.7 0.5 2.7 3 0 0 3 3 2 2 FlxA-like protein DUF2802 PF10975.8 XP_666552.1 - 0.0092 16.1 0.7 0.7 10.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) Tropomyosin_1 PF12718.7 XP_666552.1 - 0.014 15.5 6.0 0.084 13.0 1.1 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF4618 PF15397.6 XP_666552.1 - 0.015 14.7 3.4 0.51 9.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF5082 PF16888.5 XP_666552.1 - 0.017 15.4 5.9 0.19 12.0 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 XP_666552.1 - 0.018 15.4 3.1 3.2 8.2 0.7 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 XP_666552.1 - 0.019 15.5 0.9 2.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 XP_666552.1 - 0.022 15.3 7.7 0.1 13.2 2.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 XP_666552.1 - 0.023 14.1 4.5 0.042 13.2 4.5 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 XP_666552.1 - 0.026 14.8 3.9 0.81 9.9 0.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 XP_666552.1 - 0.027 14.6 0.5 3.5 7.8 0.0 2.5 3 0 0 3 3 2 0 MbeD/MobD like YscO-like PF16789.5 XP_666552.1 - 0.028 14.5 4.6 0.065 13.3 0.8 2.0 2 0 0 2 2 2 0 YscO-like protein Laminin_I PF06008.14 XP_666552.1 - 0.029 14.1 2.8 0.058 13.1 2.8 1.4 1 1 0 1 1 1 0 Laminin Domain I BRE1 PF08647.11 XP_666552.1 - 0.03 14.4 7.1 0.052 13.6 0.9 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase E2F_CC-MB PF16421.5 XP_666552.1 - 0.036 14.4 1.6 4.1 7.8 0.1 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain HAUS4 PF14735.6 XP_666552.1 - 0.037 13.7 1.3 2.8 7.6 0.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Ax_dynein_light PF10211.9 XP_666552.1 - 0.039 13.9 2.3 0.59 10.1 0.3 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.6 XP_666552.1 - 0.039 14.4 1.0 1 9.8 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Snf7 PF03357.21 XP_666552.1 - 0.039 13.5 3.9 0.16 11.6 0.5 2.0 2 0 0 2 2 2 0 Snf7 Baculo_PEP_C PF04513.12 XP_666552.1 - 0.042 13.9 0.2 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.9 XP_666552.1 - 0.052 13.2 2.8 0.096 12.4 0.3 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3086 PF11285.8 XP_666552.1 - 0.053 12.6 1.3 0.055 12.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DASH_Dad3 PF08656.10 XP_666552.1 - 0.056 13.5 0.7 4.4 7.5 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 SKA1 PF07160.12 XP_666552.1 - 0.057 13.3 2.3 0.39 10.5 0.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 GrpE PF01025.19 XP_666552.1 - 0.064 12.9 3.2 0.47 10.1 0.5 2.1 2 0 0 2 2 2 0 GrpE GAT PF03127.14 XP_666552.1 - 0.066 13.5 1.9 4.5 7.6 0.3 2.1 2 0 0 2 2 2 0 GAT domain FliD_N PF02465.18 XP_666552.1 - 0.068 13.9 3.7 0.49 11.1 1.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HalX PF08663.10 XP_666552.1 - 0.072 13.4 3.5 0.67 10.3 0.8 2.2 2 0 0 2 2 2 0 HalX domain XhlA PF10779.9 XP_666552.1 - 0.073 13.3 4.6 2.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA BLOC1_2 PF10046.9 XP_666552.1 - 0.074 13.4 2.9 6.7 7.1 0.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4600 PF15372.6 XP_666552.1 - 0.079 13.4 3.5 0.36 11.3 3.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF16 PF01519.16 XP_666552.1 - 0.09 13.3 2.2 0.48 10.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 ZapB PF06005.12 XP_666552.1 - 0.093 13.2 6.1 1.8 9.1 1.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF1845 PF08900.11 XP_666552.1 - 0.097 12.4 0.7 0.81 9.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1845) BST2 PF16716.5 XP_666552.1 - 0.098 13.2 5.6 0.15 12.6 1.4 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4047 PF13256.6 XP_666552.1 - 0.1 12.8 1.1 0.2 11.8 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) BRI3BP PF14965.6 XP_666552.1 - 0.11 12.0 0.8 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4795 PF16043.5 XP_666552.1 - 0.11 12.1 3.6 0.32 10.6 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ApoO PF09769.9 XP_666552.1 - 0.12 12.4 0.2 0.23 11.4 0.0 1.5 2 0 0 2 2 1 0 Apolipoprotein O ACP_PD PF04336.12 XP_666552.1 - 0.12 12.8 0.1 0.37 11.2 0.0 1.7 2 0 0 2 2 1 0 Acyl carrier protein phosphodiesterase MutS_IV PF05190.18 XP_666552.1 - 0.12 12.7 1.7 1 9.7 0.1 2.1 2 0 0 2 2 2 0 MutS family domain IV CCDC-167 PF15188.6 XP_666552.1 - 0.12 12.7 2.9 0.41 11.0 2.9 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 XP_666552.1 - 0.12 12.4 7.8 0.26 11.4 1.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 XP_666552.1 - 0.13 12.7 5.2 0.72 10.3 1.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 XP_666552.1 - 0.15 12.5 4.1 2.4 8.6 0.3 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Vps51 PF08700.11 XP_666552.1 - 0.17 12.0 2.8 5 7.3 0.1 2.4 2 1 0 2 2 2 0 Vps51/Vps67 DUF4407 PF14362.6 XP_666552.1 - 0.2 11.0 1.7 0.82 9.0 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 XP_666552.1 - 0.22 11.3 5.6 1.2 9.0 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 XP_666552.1 - 0.24 11.5 7.5 2.5 8.3 2.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 XP_666552.1 - 0.33 11.0 8.6 1.2 9.2 2.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FmiP_Thoc5 PF09766.9 XP_666552.1 - 0.33 10.2 5.0 0.45 9.8 0.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 TSC22 PF01166.18 XP_666552.1 - 0.34 11.2 3.1 3.5 8.0 0.4 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4665 PF15679.5 XP_666552.1 - 0.38 11.4 3.7 9.1 7.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Nas2_N PF18265.1 XP_666552.1 - 0.4 10.6 3.4 0.65 10.0 0.2 2.4 2 1 1 3 3 3 0 Nas2 N_terminal domain DUF1664 PF07889.12 XP_666552.1 - 0.41 10.7 2.8 2.1 8.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rho_Binding PF08912.11 XP_666552.1 - 0.41 11.5 7.2 3.1 8.7 1.9 2.3 2 0 0 2 2 2 0 Rho Binding Cep57_CLD_2 PF14197.6 XP_666552.1 - 0.42 10.7 6.5 2.6 8.2 2.0 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_9 PF12781.7 XP_666552.1 - 0.46 9.6 4.1 0.076 12.1 0.7 1.4 2 0 0 2 2 1 0 ATP-binding dynein motor region Swi5 PF07061.11 XP_666552.1 - 0.5 10.5 7.0 3 8.0 1.8 2.3 1 1 0 2 2 2 0 Swi5 Syntaxin-6_N PF09177.11 XP_666552.1 - 0.68 10.5 4.4 3.6 8.2 4.4 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 XP_666552.1 - 0.81 10.0 8.8 7.7 6.9 5.1 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 XP_666552.1 - 2.4 8.1 7.0 12 6.0 1.2 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat SpoIIE PF07228.12 XP_666553.1 - 3.6e-13 49.9 0.0 1.4e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 XP_666553.1 - 4.2e-13 49.5 0.4 7.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 XP_666553.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF483 PF04467.12 XP_666553.1 - 0.086 12.8 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Alba PF01918.21 XP_666554.1 - 9.9e-19 66.9 0.1 1.8e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 XP_666554.1 - 8.3e-14 51.7 0.2 1.5e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Mucin PF01456.17 XP_666555.1 - 0.0064 16.5 32.1 0.023 14.7 30.1 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.12 XP_666555.1 - 0.02 12.9 1.9 0.026 12.5 1.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 XP_666555.1 - 1.6 7.9 12.4 2.2 7.4 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.11 XP_666555.1 - 2.9 6.0 31.0 0.031 12.5 21.0 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 XP_666555.1 - 3.3 5.7 7.9 5.1 5.1 7.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_IE1 PF07340.11 XP_666559.1 - 0.023 13.7 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein TB2_DP1_HVA22 PF03134.19 XP_666560.1 - 1.4e-28 98.6 12.2 1.6e-28 98.4 8.4 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family YvrJ PF12841.7 XP_666560.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family CAF1A PF12253.8 XP_666561.1 - 2.4e-08 34.0 3.2 7.3e-08 32.5 3.2 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Peptidase_M3_N PF08439.10 XP_666561.1 - 0.045 14.0 0.1 0.22 11.8 0.1 2.2 1 0 0 1 1 1 0 Oligopeptidase F G-patch PF01585.23 XP_666562.1 - 5.3e-16 58.2 1.4 1.2e-15 57.2 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 XP_666562.1 - 7.5e-05 22.7 1.1 0.00014 21.8 1.1 1.6 1 1 0 1 1 1 1 G-patch domain IF-2B PF01008.17 XP_666563.1 - 7.2e-18 64.8 6.6 1.1e-16 60.9 6.6 2.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4298 PF14131.6 XP_666563.1 - 0.066 13.2 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) GSH-S_ATP PF02955.16 XP_666564.1 - 0.004 16.6 1.7 0.11 11.9 0.0 2.9 2 1 1 3 3 3 2 Prokaryotic glutathione synthetase, ATP-grasp domain ACT_5 PF13710.6 XP_666565.1 - 0.017 15.0 0.7 0.043 13.7 0.7 1.7 1 0 0 1 1 1 0 ACT domain ZnuA PF01297.17 XP_666565.1 - 0.08 12.3 0.1 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF730 PF05325.11 XP_666565.1 - 0.14 12.2 0.8 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Longin PF13774.6 XP_666566.1 - 2.2e-21 75.6 0.0 3.9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 XP_666567.1 - 3.4e-12 46.0 0.4 3.6e-12 45.9 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin UPRTase PF14681.6 XP_666568.1 - 2e-58 197.2 0.0 2.5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 XP_666568.1 - 0.0025 17.3 0.0 0.0051 16.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DnaJ PF00226.31 XP_666569.1 - 7.1e-12 45.3 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Patched PF02460.18 XP_666570.1 - 1.2e-100 337.9 0.0 3.1e-100 336.5 0.0 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 XP_666570.1 - 1e-20 74.2 6.3 1e-20 74.2 6.3 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 XP_666570.1 - 0.054 11.1 9.2 0.083 10.5 9.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pkinase PF00069.25 XP_666571.1 - 6e-61 206.1 1.3 1.3e-40 139.5 0.5 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666571.1 - 1.3e-27 96.7 0.2 1.5e-23 83.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 XP_666571.1 - 0.0017 17.4 0.1 0.0036 16.3 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 XP_666571.1 - 0.096 12.0 0.1 0.31 10.4 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 XP_666572.1 - 1.9e-57 194.8 0.1 2.3e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 XP_666572.1 - 7.8e-22 77.6 0.0 2e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 XP_666572.1 - 2.3e-16 60.1 1.7 1.1e-11 45.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 XP_666572.1 - 5.7e-12 45.5 0.1 2.5e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 XP_666572.1 - 1.9e-08 33.5 0.6 0.00018 20.4 1.5 2.3 1 1 1 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 XP_666572.1 - 4.6e-08 32.6 1.5 4.7e-06 25.9 2.0 2.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 XP_666572.1 - 5.5e-06 25.8 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 XP_666572.1 - 8.9e-06 25.0 0.0 2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 XP_666572.1 - 1.5e-05 24.6 0.3 2.2e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 XP_666572.1 - 0.00011 22.3 1.7 0.00081 19.6 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 XP_666572.1 - 0.00013 21.4 0.3 1.1 8.4 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 XP_666572.1 - 0.0031 16.8 1.2 0.0065 15.7 0.3 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 XP_666572.1 - 0.0099 15.5 1.6 0.046 13.3 0.4 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 XP_666572.1 - 0.011 14.9 0.0 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1848 PF08902.11 XP_666573.1 - 0.028 14.1 0.7 0.035 13.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Maf PF02545.14 XP_666574.1 - 1.1e-32 113.2 0.1 1.2e-32 113.0 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein MxiM PF11441.8 XP_666574.1 - 0.015 15.6 0.9 0.056 13.7 0.1 2.3 1 1 1 2 2 2 0 Pilot protein MxiM ChpXY PF10216.9 XP_666575.1 - 0.021 14.0 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) CopK PF11525.8 XP_666575.1 - 0.027 14.1 0.1 0.056 13.1 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein K Sec3-PIP2_bind PF15277.6 XP_666576.1 - 0.0098 16.0 0.7 0.042 14.0 0.3 2.1 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH EIF_2_alpha PF07541.12 XP_666577.1 - 7e-29 100.3 0.3 1.4e-27 96.1 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 XP_666577.1 - 1.6e-13 50.8 0.6 3.6e-13 49.6 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 XP_666577.1 - 0.28 11.8 2.6 0.43 11.2 0.2 2.4 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Rtt106 PF08512.12 XP_666578.1 - 1.1e-24 86.7 0.4 4.6e-23 81.5 0.0 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 XP_666578.1 - 9.4e-17 61.2 0.3 7.2e-13 48.8 0.2 2.6 3 0 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 XP_666578.1 - 3.1e-15 55.8 0.2 9.9e-15 54.2 0.1 1.9 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) WD40_like PF17005.5 XP_666578.1 - 0.013 14.8 0.3 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 WD40-like domain Pex14_N PF04695.13 XP_666578.1 - 0.64 10.7 2.9 1.1 9.9 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cwf_Cwc_15 PF04889.12 XP_666578.1 - 2 8.1 21.9 2.9 7.6 21.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 XP_666578.1 - 3.6 6.8 16.7 5.8 6.1 16.7 1.3 1 0 0 1 1 1 0 NOA36 protein Hint PF01079.20 XP_666579.1 - 2e-23 83.1 0.0 3.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 XP_666579.1 - 5.5e-05 23.5 0.0 0.0009 19.6 0.0 2.2 2 0 0 2 2 2 1 Hint domain DUF1317 PF07026.11 XP_666579.1 - 0.051 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) DNA_ligase_OB PF03120.16 XP_666579.1 - 0.16 11.9 0.6 3 7.8 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain PPTA PF01239.22 XP_666580.1 - 1.1e-28 98.0 18.3 1.5e-07 30.9 0.7 6.0 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 XP_666580.1 - 0.16 12.4 0.3 1.3 9.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L24e PF01246.20 XP_666581.1 - 2.1e-31 107.9 7.7 2.1e-31 107.9 7.7 2.0 3 0 0 3 3 3 1 Ribosomal protein L24e zf-FCS PF06467.14 XP_666581.1 - 0.0077 16.2 2.6 0.019 14.9 2.3 1.9 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif FDF PF09532.10 XP_666581.1 - 0.11 13.4 2.5 0.23 12.4 2.5 1.5 1 0 0 1 1 1 0 FDF domain FYVE PF01363.21 XP_666582.1 - 5 7.3 13.8 0.91 9.7 8.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger DHHC PF01529.20 XP_666583.1 - 4.3 7.5 16.1 0.65 10.1 1.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase tRNA_U5-meth_tr PF05958.11 XP_666584.1 - 1.5e-10 40.7 1.9 1.1e-09 37.8 1.4 2.4 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 XP_666584.1 - 2.1e-10 40.6 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_666584.1 - 4.4e-07 30.5 0.0 8.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 XP_666584.1 - 1.2e-06 28.2 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 XP_666584.1 - 2.5e-05 23.8 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 XP_666584.1 - 2.6e-05 23.7 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 XP_666584.1 - 0.00038 20.5 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666584.1 - 0.002 18.8 0.0 0.0042 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_666584.1 - 0.0092 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_666584.1 - 0.051 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 XP_666584.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_15 PF09445.10 XP_666584.1 - 0.09 12.3 0.1 0.23 11.0 0.1 1.8 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 XP_666584.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sipho_Gp157 PF05565.11 XP_666585.1 - 0.00062 19.8 9.3 0.00062 19.8 9.3 3.6 4 0 0 4 4 4 1 Siphovirus Gp157 DUF4201 PF13870.6 XP_666585.1 - 0.0087 15.8 9.0 0.0087 15.8 9.0 4.7 3 1 2 5 5 5 1 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 XP_666585.1 - 0.011 15.8 12.3 0.011 15.8 12.3 5.0 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Mrpl_C PF18502.1 XP_666585.1 - 0.038 14.3 1.1 0.038 14.3 1.1 2.6 2 1 1 3 3 3 0 54S ribosomal protein L8 C-terminal domain Cas6b_C PF17262.2 XP_666585.1 - 0.17 12.0 3.2 0.18 11.9 0.4 2.5 2 1 0 2 2 2 0 Cas6b C-terminal domain DUF1759 PF03564.15 XP_666585.1 - 0.2 11.6 8.5 0.14 12.1 1.5 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1759) FUSC PF04632.12 XP_666585.1 - 1.4 7.4 3.6 2.2 6.7 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lipoprotein_20 PF13942.6 XP_666585.1 - 4.9 7.0 20.3 0.63 9.9 10.6 3.0 2 2 0 2 2 2 0 YfhG lipoprotein ATG16 PF08614.11 XP_666585.1 - 6.5 6.9 34.6 0.092 13.0 14.2 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Bromodomain PF00439.25 XP_666586.1 - 2.8e-22 78.6 1.6 1.1e-21 76.6 0.3 2.1 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 XP_666586.1 - 0.0044 17.1 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ig_C17orf99 PF17736.1 XP_666586.1 - 0.067 13.2 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 C17orf99 Ig domain Hydrolase PF00702.26 XP_666587.1 - 1.2e-13 51.9 0.0 0.00021 21.6 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 XP_666587.1 - 1.8e-12 47.1 0.0 1.8e-12 47.1 0.0 2.6 4 0 0 4 4 4 1 E1-E2 ATPase HAD_2 PF13419.6 XP_666587.1 - 0.027 14.6 0.0 0.62 10.1 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_666587.1 - 0.034 14.2 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Nuc_sug_transp PF04142.15 XP_666588.1 - 6.2e-70 235.8 28.5 5.1e-47 160.6 8.3 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 XP_666588.1 - 9.8e-06 25.8 33.8 6.9e-05 23.0 9.6 3.3 3 1 1 4 4 4 2 EamA-like transporter family EmrE PF13536.6 XP_666588.1 - 0.00062 19.4 2.5 0.00062 19.4 2.5 2.7 1 1 1 3 3 3 1 Putative multidrug resistance efflux transporter P63C PF10546.9 XP_666588.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 P63C domain TMEM234 PF10639.9 XP_666588.1 - 0.8 9.7 13.9 0.55 10.3 1.8 2.8 2 1 0 2 2 2 0 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 XP_666589.1 - 1.2e-62 211.9 11.2 1.8e-62 211.3 11.2 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 XP_666589.1 - 1.2e-08 35.2 23.7 5.3e-06 26.6 6.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 XP_666589.1 - 2.4e-05 23.7 3.2 2.4e-05 23.7 3.2 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 XP_666589.1 - 0.00044 19.7 9.2 0.0025 17.2 0.9 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family TauE PF01925.19 XP_666589.1 - 0.00085 19.0 1.3 0.00085 19.0 1.3 3.0 2 1 1 3 3 3 1 Sulfite exporter TauE/SafE UAA PF08449.11 XP_666589.1 - 0.0044 16.3 11.2 0.0074 15.5 11.2 1.4 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 XP_666589.1 - 0.0054 16.4 4.8 0.035 13.7 4.8 2.0 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter CRT-like PF08627.10 XP_666589.1 - 0.0089 15.0 9.6 0.021 13.8 0.7 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF5368 PF17336.2 XP_666589.1 - 0.19 11.9 7.7 1.9 8.7 0.6 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5368) TMEM234 PF10639.9 XP_666589.1 - 0.41 10.7 8.0 1.2 9.2 0.7 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 DMT_6 PF04342.12 XP_666589.1 - 0.44 10.8 8.2 2.4 8.4 1.1 2.5 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Sas10_Utp3 PF04000.15 XP_666590.1 - 0.58 10.8 5.8 0.16 12.6 0.7 2.5 2 1 0 3 3 3 0 Sas10/Utp3/C1D family SNF2_N PF00176.23 XP_666591.1 - 1.5e-58 198.2 0.0 2.7e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_666591.1 - 4.6e-20 72.0 0.0 1.1e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 XP_666591.1 - 3.7e-17 62.2 0.0 8.5e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Chromo PF00385.24 XP_666591.1 - 3.2e-12 46.1 0.1 2.1e-05 24.3 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 XP_666591.1 - 2e-08 34.5 0.0 8.4e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_666591.1 - 0.00043 20.1 0.0 0.98 9.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Peptidase_M16_C PF05193.21 XP_666593.1 - 1.3e-12 48.2 0.2 4.6e-10 39.8 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_666593.1 - 8.9e-10 38.7 0.0 4e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pyr_redox_2 PF07992.14 XP_666594.1 - 4.4e-06 26.1 0.0 0.0037 16.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 XP_666594.1 - 0.00017 21.6 0.0 0.00052 20.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 XP_666594.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 XP_666595.1 - 3.6e-56 190.9 0.0 4.2e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 XP_666595.1 - 0.00016 20.8 0.0 0.00031 19.9 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Staphopain_pro PF14731.6 XP_666595.1 - 0.036 14.0 1.9 0.1 12.6 1.6 1.9 1 1 0 1 1 1 0 Staphopain proregion NAF PF03822.14 XP_666595.1 - 0.12 12.5 0.4 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 NAF domain DUF5605 PF18310.1 XP_666595.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) DUF417 PF04224.12 XP_666596.1 - 0.036 13.6 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF417 NAGLU_N PF12971.7 XP_666597.1 - 0.051 13.4 0.1 0.21 11.4 0.1 2.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Phage_TAC_6 PF09550.10 XP_666598.1 - 2e-06 28.1 0.9 54 4.3 0.0 6.8 7 0 0 7 7 7 0 Phage tail assembly chaperone protein, TAC Nsp1_C PF05064.13 XP_666598.1 - 0.0069 16.2 4.3 72 3.2 0.1 6.0 5 0 0 5 5 5 0 Nsp1-like C-terminal region Toprim_Crpt PF13342.6 XP_666598.1 - 1.2 9.2 17.3 15 5.6 0.2 6.4 5 0 0 5 5 5 0 C-terminal repeat of topoisomerase RHH_3 PF12651.7 XP_666598.1 - 2.5 8.1 12.2 41 4.2 0.0 5.4 7 0 0 7 7 7 0 Ribbon-helix-helix domain Alpha_GJ PF03229.13 XP_666599.1 - 0.058 14.0 1.7 0.11 13.1 1.7 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2681 PF10883.8 XP_666599.1 - 8.4 6.9 7.9 4.6 7.7 2.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CENP-B_dimeris PF09026.10 XP_666599.1 - 10 6.6 18.8 3.1 8.2 3.2 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Red1 PF07964.11 XP_666600.1 - 1 7.5 53.2 1.6 6.9 53.2 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Colicin_immun PF09204.10 XP_666601.1 - 0.016 15.8 1.7 0.056 14.0 1.7 2.0 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity GIDA PF01134.22 XP_666602.1 - 0.0048 16.0 1.5 0.0051 15.9 1.5 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A VP7 PF00434.18 XP_666602.1 - 0.0086 15.3 0.7 0.0087 15.2 0.7 1.0 1 0 0 1 1 1 1 Glycoprotein VP7 Calc_CGRP_IAPP PF00214.19 XP_666602.1 - 0.07 13.5 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family NFRKB_winged PF14465.6 XP_666602.1 - 0.071 13.3 0.1 0.084 13.1 0.1 1.2 1 0 0 1 1 1 0 NFRKB Winged Helix-like O-antigen_lig PF13425.6 XP_666602.1 - 0.11 11.3 3.5 0.12 11.2 3.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ketoacyl-synt PF00109.26 XP_666606.1 - 4.7e-69 232.8 0.0 8.7e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 XP_666606.1 - 2.5e-58 196.9 0.0 2.4e-49 167.7 0.0 2.5 2 0 0 2 2 2 2 KR domain Acyl_transf_1 PF00698.21 XP_666606.1 - 3.6e-46 158.1 0.0 5.3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 XP_666606.1 - 4.6e-41 139.6 0.0 8.6e-41 138.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 XP_666606.1 - 8.9e-14 51.6 0.0 2.6e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 XP_666606.1 - 2.7e-09 37.3 0.1 8.5e-09 35.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 XP_666606.1 - 2.4e-08 33.7 2.1 6.2e-07 29.1 0.0 3.0 4 0 0 4 4 4 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 XP_666606.1 - 4.1e-07 30.5 0.2 1.1e-06 29.1 0.2 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 XP_666606.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 XP_666606.1 - 0.0018 18.2 1.2 0.004 17.0 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 XP_666606.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 XP_666606.1 - 0.04 15.0 0.0 0.15 13.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 XP_666606.1 - 0.045 13.2 0.1 0.88 9.0 0.0 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Peptidase_M24 PF00557.24 XP_666607.1 - 6.4e-39 133.8 0.0 9.1e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 XP_666607.1 - 2.5e-33 115.4 3.5 2.6e-31 108.9 3.0 2.8 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 XP_666607.1 - 5.5e-20 71.2 0.3 1.1e-19 70.2 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 XP_666607.1 - 2.1e-14 54.3 0.0 2.1e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DUF2121 PF09894.9 XP_666607.1 - 0.001 18.7 1.1 0.0014 18.2 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) DivIC PF04977.15 XP_666608.1 - 0.016 15.0 0.1 0.016 15.0 0.1 3.8 3 2 1 4 4 4 0 Septum formation initiator Seadorna_VP6 PF07407.11 XP_666608.1 - 0.027 13.4 0.1 0.027 13.4 0.1 2.0 2 0 0 2 2 2 0 Seadornavirus VP6 protein HALZ PF02183.18 XP_666608.1 - 0.037 14.2 9.2 0.096 12.9 2.2 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Glyco_hydro_67N PF03648.14 XP_666608.1 - 0.51 10.6 3.1 8.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Glycosyl hydrolase family 67 N-terminus IFP_35_N PF07334.13 XP_666608.1 - 1 9.5 10.1 2.6 8.2 2.3 3.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Raco_middle PF17651.1 XP_666608.1 - 1.1 8.9 3.1 0.69 9.6 0.2 2.1 2 1 0 2 2 2 0 RACo middle region CtIP_N PF10482.9 XP_666608.1 - 1.4 9.0 18.0 0.26 11.3 0.5 3.4 3 1 1 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Fzo_mitofusin PF04799.13 XP_666608.1 - 4.1 6.9 10.3 0.43 10.1 1.0 3.1 2 1 1 3 3 3 0 fzo-like conserved region AAA_33 PF13671.6 XP_666609.1 - 0.0065 16.6 0.1 0.0082 16.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain RRM_1 PF00076.22 XP_666610.1 - 0.00022 21.0 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCP_C_terminal PF04130.13 XP_666613.1 - 9.8e-08 31.8 8.4 9.8e-08 31.8 8.4 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal PAN_3 PF08277.12 XP_666613.1 - 0.015 15.1 0.3 0.046 13.5 0.3 1.9 1 0 0 1 1 1 0 PAN-like domain Phage_RpbA PF10789.9 XP_666613.1 - 0.019 15.0 0.2 0.83 9.7 0.0 2.7 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA Condensation PF00668.20 XP_666614.1 - 4.9e-09 35.4 0.0 1.2e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Condensation domain DUF3932 PF13068.6 XP_666615.1 - 0.059 13.6 0.1 0.065 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) DUF438 PF04282.13 XP_666615.1 - 0.086 12.8 0.6 0.099 12.6 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF438) Sas10 PF09368.10 XP_666616.1 - 1.5e-21 76.7 10.8 1.5e-21 76.7 10.8 3.4 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 XP_666616.1 - 2.4e-14 53.7 1.7 2.4e-14 53.7 1.7 4.1 4 1 1 5 5 5 1 Sas10/Utp3/C1D family PrmA PF06325.13 XP_666617.1 - 2.7e-09 36.9 0.1 4.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 XP_666617.1 - 1.3e-08 35.4 0.0 2.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666617.1 - 4.6e-08 33.0 0.1 7.7e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_666617.1 - 1.2e-06 29.0 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_666617.1 - 3e-05 23.9 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 XP_666617.1 - 6.2e-05 22.1 0.1 8.5e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 XP_666617.1 - 0.00034 20.6 0.7 0.00075 19.5 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 XP_666617.1 - 0.00072 19.1 0.2 0.0012 18.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 XP_666617.1 - 0.0032 17.2 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 XP_666617.1 - 0.005 16.6 0.1 0.0076 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 XP_666617.1 - 0.0061 16.1 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 PRMT5 PF05185.16 XP_666617.1 - 0.013 15.4 0.4 0.047 13.5 0.1 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 XP_666617.1 - 0.026 15.3 0.0 0.066 14.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 XP_666617.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Rsm22 PF09243.10 XP_666617.1 - 0.048 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 XP_666617.1 - 0.058 13.4 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 XP_666618.1 - 3.8e-31 108.2 0.1 9.5e-31 106.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_666618.1 - 1.4e-23 83.4 2.1 2e-23 82.8 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_666618.1 - 7.1e-06 26.1 0.1 7.1e-06 26.1 0.1 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 XP_666618.1 - 0.021 15.1 0.1 0.1 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain ACPS PF01648.20 XP_666620.1 - 3.1e-15 56.3 0.0 6.5e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DHHC PF01529.20 XP_666621.1 - 1.3e-27 96.6 15.9 1.3e-27 96.6 15.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase tRNA-synt_2b PF00587.25 XP_666622.1 - 9.6e-35 120.2 0.0 1.5e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 XP_666622.1 - 4.1e-14 52.7 9.1 4.1e-14 52.7 9.1 1.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Casc1 PF12366.8 XP_666622.1 - 0.31 10.5 3.5 3.9 6.9 2.8 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 TrmO PF01980.16 XP_666623.1 - 2.6e-28 98.6 0.0 3.9e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 tRNA-methyltransferase O CactinC_cactus PF09732.9 XP_666624.1 - 2.4e-42 143.8 6.1 6.1e-42 142.5 6.1 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 XP_666624.1 - 1e-05 25.3 7.0 0.00011 22.0 7.0 2.4 1 1 0 1 1 1 1 Conserved mid region of cactin U3_assoc_6 PF08640.11 XP_666624.1 - 0.00034 20.6 2.6 0.00034 20.6 2.6 2.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 CLASP_N PF12348.8 XP_666625.1 - 2.9e-05 23.7 6.4 2.9e-05 23.7 6.4 3.2 3 0 0 3 3 3 1 CLASP N terminal DUF896 PF05979.12 XP_666625.1 - 0.049 13.5 1.3 0.4 10.6 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Plus-3 PF03126.18 XP_666627.1 - 0.028 14.9 0.5 0.033 14.7 0.5 1.1 1 0 0 1 1 1 0 Plus-3 domain DUF2780 PF11075.8 XP_666627.1 - 0.15 12.2 0.7 0.18 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) DNA_pol_phi PF04931.13 XP_666628.1 - 0.035 12.2 23.0 0.052 11.7 23.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 XP_666628.1 - 0.15 11.4 22.5 0.2 11.0 22.5 1.3 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 XP_666628.1 - 7.8 4.9 16.2 10 4.5 16.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DJ-1_PfpI PF01965.24 XP_666629.1 - 4.9e-34 117.5 0.1 5.6e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 XP_666629.1 - 0.0093 15.6 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 XP_666629.1 - 0.18 11.4 0.0 1.4 8.5 0.0 2.0 1 1 1 2 2 2 0 ThiJ/PfpI family-like MORN PF02493.20 XP_666630.1 - 3.6e-61 199.6 76.0 3.9e-09 35.9 3.0 12.4 13 1 0 13 13 13 11 MORN repeat Aa_trans PF01490.18 XP_666631.1 - 8.2e-35 120.3 46.4 2.6e-34 118.6 46.4 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_16 PF10294.9 XP_666632.1 - 2.2e-22 79.6 0.0 4.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Ank_4 PF13637.6 XP_666632.1 - 2.6e-15 56.6 1.5 2.5e-07 31.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 XP_666632.1 - 9.9e-15 54.4 1.4 6e-11 42.4 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 XP_666632.1 - 4.4e-12 46.4 1.5 1.4e-07 32.0 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 XP_666632.1 - 5.5e-12 45.6 0.6 2.5e-05 24.5 0.6 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 XP_666632.1 - 8e-12 44.3 0.2 0.00063 20.0 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat MTS PF05175.14 XP_666632.1 - 0.0087 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 XP_666632.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666632.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 XP_666632.1 - 0.034 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 XP_666632.1 - 0.04 14.6 0.0 0.16 12.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666632.1 - 0.047 14.4 0.0 0.16 12.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ETRAMP PF09716.10 XP_666633.1 - 0.17 12.0 3.8 10 6.2 0.2 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Tyr_Deacylase PF02580.16 XP_666634.1 - 5e-48 163.3 0.0 5.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RRM_1 PF00076.22 XP_666635.1 - 8.1e-29 99.3 2.2 1.6e-13 50.2 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_666635.1 - 4.7e-05 23.0 0.3 0.079 12.6 0.1 2.6 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 XP_666635.1 - 0.00012 23.1 2.2 0.00012 23.1 2.2 2.4 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 XP_666635.1 - 0.00039 20.2 0.4 2.4 8.1 0.0 3.9 3 2 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 XP_666635.1 - 0.011 15.8 0.3 0.081 13.0 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif LPD7 PF18821.1 XP_666635.1 - 0.11 12.7 0.2 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Bromodomain PF00439.25 XP_666636.1 - 6.5e-19 67.8 0.2 2.6e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain Rop PF01815.16 XP_666636.1 - 7.9 6.4 5.6 35 4.4 0.2 3.0 3 0 0 3 3 3 0 Rop protein JAB PF01398.21 XP_666639.1 - 0.00012 22.0 0.1 0.41 10.6 0.0 2.6 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Adeno_shaft PF00608.17 XP_666639.1 - 0.089 12.6 0.7 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) dUTPase PF00692.19 XP_666640.1 - 1.5e-14 53.8 0.0 1.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF2436 PF10365.9 XP_666641.1 - 0.14 11.9 0.1 0.36 10.5 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2436) DUF632 PF04782.12 XP_666643.1 - 2.1 7.6 18.0 7.6 5.8 18.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF632) GPS PF01825.21 XP_666644.1 - 0.058 13.9 0.8 0.16 12.6 0.8 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif DUF1981 PF09324.10 XP_666644.1 - 0.18 11.7 0.5 1.7 8.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) Prp18 PF02840.15 XP_666645.1 - 7.3e-55 185.0 0.4 9e-55 184.7 0.4 1.1 1 0 0 1 1 1 1 Prp18 domain Lipoprotein_10 PF03202.13 XP_666645.1 - 0.1 13.0 2.0 0.21 12.0 0.6 1.9 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region DUF4731 PF15875.5 XP_666646.1 - 0.062 13.5 0.4 0.062 13.5 0.4 3.2 3 1 1 5 5 5 0 Domain of unknown function (DUF4731) BTV_NS2 PF04514.12 XP_666646.1 - 2 7.2 9.9 1.7 7.4 1.2 2.2 1 1 1 2 2 2 0 Bluetongue virus non-structural protein NS2 ABC2_membrane PF01061.24 XP_666648.1 - 7.7e-31 107.2 26.7 7.7e-31 107.2 26.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 XP_666648.1 - 3.8e-23 82.5 0.0 5.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 XP_666648.1 - 7e-08 32.6 6.0 0.00016 21.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 XP_666648.1 - 6e-05 22.3 37.0 0.00032 19.9 37.0 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 XP_666648.1 - 0.0002 20.9 0.0 0.44 10.0 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 XP_666648.1 - 0.0021 18.0 0.2 0.0041 17.0 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 XP_666648.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 XP_666648.1 - 0.011 16.2 1.0 0.014 15.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 XP_666648.1 - 0.028 14.2 0.3 0.068 12.9 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 XP_666648.1 - 0.03 14.1 0.2 6.7 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 XP_666648.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 XP_666648.1 - 0.059 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 XP_666648.1 - 0.088 12.9 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 XP_666648.1 - 0.097 13.2 0.0 0.23 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 XP_666648.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 XP_666648.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 XP_666648.1 - 0.13 11.3 0.3 0.26 10.3 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pro_isomerase PF00160.21 XP_666650.1 - 6.7e-50 169.4 0.0 1.7e-49 168.2 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 XP_666650.1 - 6e-07 30.1 0.0 0.26 12.2 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 XP_666650.1 - 5.6e-05 22.3 0.0 0.0019 17.2 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 XP_666650.1 - 0.0033 17.7 0.2 3.5 8.0 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Bac_small_YrzI PF09501.10 XP_666650.1 - 0.079 13.1 0.3 0.51 10.5 0.3 2.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) RNA_POL_M_15KD PF02150.16 XP_666651.1 - 1.8e-06 27.7 0.6 3.6e-06 26.8 0.6 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 XP_666651.1 - 0.035 14.0 1.2 0.055 13.4 1.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 XP_666651.1 - 0.72 10.4 4.4 1.9 9.1 4.6 1.6 1 1 0 1 1 1 0 Zinc-finger double domain RPAP2_Rtr1 PF04181.13 XP_666652.1 - 7.1e-12 45.5 0.2 7.1e-12 45.5 0.2 3.4 4 0 0 4 4 4 1 Rtr1/RPAP2 family Caldesmon PF02029.15 XP_666652.1 - 5.2e-05 22.2 0.3 5.2e-05 22.2 0.3 2.1 1 1 1 2 2 2 1 Caldesmon PAXIP1_C PF15364.6 XP_666652.1 - 0.00071 19.9 15.9 0.00071 19.9 15.9 4.3 1 1 2 4 4 4 1 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3915 PF13054.6 XP_666652.1 - 3.8 7.5 18.2 0.021 14.8 2.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) SSrecog PF03531.14 XP_666653.1 - 0.037 14.0 1.3 0.51 10.3 0.2 2.3 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) DUF334 PF03904.13 XP_666653.1 - 4.4 6.8 10.2 0.43 10.1 5.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Ldh_1_N PF00056.23 XP_666654.1 - 3e-35 121.4 0.3 5.6e-35 120.5 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 XP_666654.1 - 8.1e-25 87.7 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 XP_666654.1 - 0.0015 18.1 0.1 0.0074 15.9 0.0 2.1 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase 3HCDH_N PF02737.18 XP_666654.1 - 0.0067 16.3 0.8 0.016 15.1 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 XP_666654.1 - 0.028 14.0 1.1 0.1 12.2 1.1 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 XP_666655.1 - 8.4e-43 145.8 0.4 2.3e-42 144.4 0.2 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 XP_666655.1 - 1e-29 103.6 0.1 1.5e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 XP_666655.1 - 0.0002 21.9 0.3 0.001 19.6 0.1 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 XP_666655.1 - 0.00022 20.9 1.4 0.0014 18.2 0.8 2.6 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 XP_666655.1 - 0.012 15.2 1.7 0.035 13.6 0.1 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase MIT_C PF16565.5 XP_666655.1 - 0.05 13.6 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Shikimate_DH PF01488.20 XP_666655.1 - 0.059 13.4 0.6 0.9 9.6 0.2 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 XP_666655.1 - 0.081 12.8 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.20 XP_666656.1 - 3.7e-17 62.4 0.5 9.1e-17 61.2 0.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 XP_666656.1 - 1.2e-13 51.8 0.2 5.2e-07 30.2 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_666656.1 - 5.4e-08 32.8 0.0 5.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) TFIID_30kDa PF03540.13 XP_666658.1 - 7.8e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit RNA_pol_Rpb1_4 PF05000.17 XP_666658.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 4 E1-E2_ATPase PF00122.20 XP_666660.1 - 7e-22 77.8 1.6 1.4e-19 70.3 0.0 4.0 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 XP_666660.1 - 5.2e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 XP_666660.1 - 3.4e-06 27.5 0.1 0.03 14.6 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 XP_666660.1 - 0.0061 16.2 0.0 0.023 14.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus BTRD1 PF17660.1 XP_666660.1 - 0.064 13.1 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Prismane PF03063.20 XP_666660.1 - 0.16 10.6 0.2 0.42 9.2 0.0 1.7 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family RRM_1 PF00076.22 XP_666661.1 - 1.3e-36 124.3 0.0 1.9e-18 66.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_666661.1 - 2.3e-06 27.4 0.0 1.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 XP_666661.1 - 0.0026 17.8 0.8 0.83 9.7 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 XP_666661.1 - 0.041 13.9 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 XP_666661.1 - 0.071 13.2 0.0 6.2 7.0 0.0 3.3 2 1 0 2 2 2 0 RNA recognition motif zf-CCHC PF00098.23 XP_666662.1 - 4.7e-11 42.2 25.2 0.00024 21.0 0.2 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 XP_666662.1 - 0.0032 17.2 25.8 0.044 13.5 0.8 4.5 4 0 0 4 4 4 3 Zinc knuckle HTH_38 PF13936.6 XP_666662.1 - 0.049 13.4 1.5 0.11 12.3 1.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PepSY_2 PF13670.6 XP_666662.1 - 0.086 12.8 0.5 0.2 11.6 0.5 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Desulfoferrod_N PF06397.12 XP_666662.1 - 0.16 11.7 3.6 1.2 8.8 0.1 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF489 PF04356.12 XP_666662.1 - 0.26 11.3 3.6 0.23 11.5 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF4996 PF16387.5 XP_666662.1 - 0.39 11.2 2.8 1 9.9 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function zf-CCHC_2 PF13696.6 XP_666662.1 - 1.1 9.1 26.4 0.55 10.1 1.2 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-CHC2 PF01807.20 XP_666662.1 - 7.3 6.5 14.1 3.8 7.4 0.2 3.7 3 1 1 4 4 4 0 CHC2 zinc finger Bromodomain PF00439.25 XP_666664.1 - 0.18 11.9 2.9 0.86 9.7 0.9 3.0 2 0 0 2 2 2 0 Bromodomain Ribosomal_L18 PF17135.4 XP_666665.1 - 2.3e-78 261.9 4.4 2.5e-78 261.8 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 XP_666665.1 - 3.2e-05 24.6 0.1 0.00028 21.6 0.1 2.1 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nup54 PF13874.6 XP_666666.1 - 1.6e-22 80.1 3.0 1.6e-22 80.1 3.0 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Occludin_ELL PF07303.13 XP_666666.1 - 1 10.1 7.6 0.97 10.2 1.0 3.2 2 0 0 2 2 2 0 Occludin homology domain Vac14_Fab1_bd PF12755.7 XP_666667.1 - 0.00084 19.9 0.1 0.002 18.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 XP_666667.1 - 0.064 13.3 2.9 0.11 12.5 0.1 2.4 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF4533 PF15047.6 XP_666668.1 - 0.00052 19.7 1.0 0.00086 18.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DUF948 PF06103.11 XP_666668.1 - 0.011 15.9 1.3 0.29 11.4 0.9 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 XP_666668.1 - 0.013 16.0 5.1 0.31 11.6 3.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal P4Ha_N PF08336.11 XP_666668.1 - 0.018 15.1 1.5 0.46 10.5 0.7 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Csm1_N PF18504.1 XP_666668.1 - 0.023 15.0 2.1 0.023 15.0 2.1 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain DHR10 PF18595.1 XP_666668.1 - 0.023 14.8 1.7 0.023 14.8 1.7 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4509 PF14970.6 XP_666668.1 - 0.038 13.9 4.1 0.052 13.5 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) ABC_tran_CTD PF16326.5 XP_666668.1 - 0.044 14.0 1.0 0.044 14.0 1.0 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain BCAS2 PF05700.11 XP_666668.1 - 0.056 13.1 3.7 0.39 10.4 2.3 2.1 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF4164 PF13747.6 XP_666668.1 - 0.26 11.6 4.2 11 6.4 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FAM76 PF16046.5 XP_666668.1 - 0.29 10.4 3.2 0.36 10.1 3.2 1.3 1 0 0 1 1 1 0 FAM76 protein Prp19 PF08606.11 XP_666668.1 - 0.64 10.1 4.3 0.86 9.6 1.3 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like KELK PF15796.5 XP_666668.1 - 0.65 10.5 7.3 0.067 13.6 1.9 2.2 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 XP_666668.1 - 1.4 9.0 5.0 0.78 9.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 XP_666668.1 - 3.6 8.1 9.7 10 6.7 9.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region eIF2A PF08662.11 XP_666669.1 - 2.1e-53 181.1 0.0 3.7e-43 147.7 0.0 3.4 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF5344 PF17279.2 XP_666671.1 - 0.013 16.1 2.4 0.025 15.2 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5344) PGK PF00162.19 XP_666672.1 - 9.7e-139 462.5 0.8 1.1e-138 462.3 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF5053 PF16476.5 XP_666672.1 - 0.14 11.8 0.1 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) NARP1 PF12569.8 XP_666673.1 - 1e-15 57.6 7.2 2.2e-15 56.6 7.2 1.6 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 Ufd2P_core PF10408.9 XP_666674.1 - 1.1e-126 424.0 24.7 1.3e-126 423.8 24.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 XP_666674.1 - 5.8e-24 84.1 1.6 4.1e-23 81.3 1.3 2.4 2 0 0 2 2 2 1 U-box domain DUF2999 PF11212.8 XP_666674.1 - 0.021 15.1 0.1 0.06 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Ran_BP1 PF00638.18 XP_666675.1 - 0.0025 18.1 0.0 0.0033 17.7 0.0 1.1 1 0 0 1 1 1 1 RanBP1 domain SMK-1 PF04802.15 XP_666676.1 - 1.4e-25 90.3 9.7 1.4e-25 90.3 9.7 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Peptidase_M24 PF00557.24 XP_666677.1 - 1.5e-15 57.4 0.0 2.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 adh_short PF00106.25 XP_666678.1 - 1.1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 XP_666678.1 - 0.0019 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 XP_666678.1 - 0.0072 15.5 0.1 0.0081 15.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 XP_666678.1 - 0.01 15.8 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 XP_666678.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 XP_666678.1 - 0.092 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 XP_666678.1 - 0.2 11.0 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MHC_I PF00129.18 XP_666679.1 - 0.025 14.1 0.4 0.038 13.5 0.4 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF1878 PF08963.10 XP_666679.1 - 0.064 13.8 1.5 0.098 13.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) CREPT PF16566.5 XP_666679.1 - 0.14 12.3 4.4 0.2 11.8 4.4 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour bZIP_1 PF00170.21 XP_666679.1 - 0.23 11.6 7.9 0.24 11.5 2.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.25 XP_666680.1 - 1.7e-57 194.8 0.0 2.2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666680.1 - 3.6e-39 134.6 0.0 8.1e-39 133.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_666680.1 - 3.5e-08 33.1 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 XP_666680.1 - 2.9e-06 26.3 0.1 4e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 XP_666680.1 - 0.0093 14.9 0.3 0.025 13.6 0.1 1.6 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 XP_666680.1 - 0.1 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Saf_2TM PF18303.1 XP_666680.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain RRM_1 PF00076.22 XP_666681.1 - 3.9e-09 36.2 1.4 3.4e-05 23.6 0.1 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_666681.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Tli4_N PF18443.1 XP_666681.1 - 0.2 12.0 2.4 14 6.1 0.0 2.7 1 1 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain EMP24_GP25L PF01105.24 XP_666682.1 - 2.5e-18 66.7 0.2 3.5e-18 66.2 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNB PF00773.19 XP_666683.1 - 2.1e-100 336.2 6.5 2.1e-100 336.2 6.5 2.1 3 0 0 3 3 3 1 RNB domain PsbL PF02419.17 XP_666684.1 - 0.085 12.9 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 PsbL protein Strabismus PF06638.11 XP_666684.1 - 0.1 11.2 0.0 0.18 10.5 0.0 1.3 1 1 0 1 1 1 0 Strabismus protein DUF5104 PF17117.5 XP_666685.1 - 0.026 14.9 5.6 0.81 10.2 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5104) V-SNARE_C PF12352.8 XP_666685.1 - 0.043 14.1 0.4 0.18 12.1 0.3 2.1 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Vip3A_N PF12495.8 XP_666685.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal PRT_C PF08372.10 XP_666685.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Plk4_PB2 PF18409.1 XP_666685.1 - 0.59 10.8 6.0 1.1 10.0 0.6 2.6 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Fib_alpha PF08702.10 XP_666685.1 - 1.2 9.3 9.1 0.68 10.1 0.1 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 XP_666685.1 - 6.6 7.0 11.2 5.1 7.4 6.3 2.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 XP_666686.1 - 5.2e-56 189.9 4.3 5.2e-56 189.9 4.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666686.1 - 3.9e-30 105.0 0.3 7.4e-29 100.8 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 XP_666686.1 - 1.9e-05 24.4 0.1 4.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 XP_666686.1 - 0.0085 15.5 0.6 0.016 14.6 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 XP_666686.1 - 0.012 15.0 0.0 0.024 13.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 XP_666686.1 - 0.29 11.0 0.0 0.48 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Baculo_LEF-10 PF07206.11 XP_666687.1 - 0.13 12.4 0.8 0.6 10.3 0.2 2.3 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) PDEase_I PF00233.19 XP_666688.1 - 3.8e-46 157.7 14.6 2.5e-45 155.1 14.6 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase V_ATPase_I PF01496.19 XP_666689.1 - 0.084 10.8 0.4 0.13 10.1 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cullin PF00888.22 XP_666690.1 - 3.6e-21 75.4 25.3 1e-18 67.3 25.3 3.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 XP_666690.1 - 0.0054 16.7 3.3 0.029 14.4 3.3 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.19 XP_666690.1 - 0.032 14.1 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PIG-H PF10181.9 XP_666690.1 - 0.09 12.6 0.7 0.74 9.7 0.0 2.8 3 0 0 3 3 3 0 GPI-GlcNAc transferase complex, PIG-H component Chordopox_RPO7 PF05864.12 XP_666690.1 - 0.11 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TMEM208_SND2 PF05620.11 XP_666692.1 - 5.5e-13 49.0 14.2 7.9e-08 32.3 7.8 2.0 1 1 1 2 2 2 2 SRP-independent targeting protein 2/TMEM208 NT-C2 PF10358.9 XP_666693.1 - 7.9e-19 67.8 0.0 2.1e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Alph_Pro_TM PF09608.10 XP_666693.1 - 0.14 12.0 0.9 0.3 10.9 0.7 1.6 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DUF2968 PF11180.8 XP_666693.1 - 0.29 10.8 7.5 0.12 12.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4140 PF13600.6 XP_666693.1 - 2.6 8.6 5.9 2.3 8.7 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 XP_666693.1 - 3.2 8.1 13.1 0.37 11.1 1.9 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain HAUS6_N PF14661.6 XP_666693.1 - 9.2 5.8 8.6 0.76 9.3 2.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Prp19 PF08606.11 XP_666694.1 - 2.7e-29 100.9 0.5 5.5e-29 100.0 0.5 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 XP_666694.1 - 3.5e-05 23.9 0.1 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 1 U-box domain WD40 PF00400.32 XP_666694.1 - 7.4e-05 23.4 1.8 0.03 15.2 0.2 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-Nse PF11789.8 XP_666694.1 - 0.0018 18.0 0.3 0.005 16.6 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 XP_666694.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein ANAPC4_WD40 PF12894.7 XP_666694.1 - 0.012 15.9 0.1 2.5 8.5 0.0 3.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 XP_666695.1 - 4.6e-48 163.3 0.0 8.9e-48 162.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_666695.1 - 5.1e-27 94.4 0.3 1.4e-25 89.8 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 XP_666695.1 - 1.4e-09 38.1 0.0 6e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.15 XP_666695.1 - 6e-08 32.9 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 XP_666695.1 - 0.036 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase YjzC PF14168.6 XP_666696.1 - 0.032 14.6 1.2 3.1 8.2 0.0 2.9 2 0 0 2 2 2 0 YjzC-like protein TolA_bind_tri PF16331.5 XP_666696.1 - 2 8.5 32.0 1.1 9.4 10.8 5.4 4 1 1 5 5 5 0 TolA binding protein trimerisation Lebercilin PF15619.6 XP_666696.1 - 3.6 7.2 48.1 0.12 12.1 17.9 4.2 3 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.6 XP_666696.1 - 4.5 7.8 24.4 0.058 13.8 3.2 4.7 3 2 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 XP_666696.1 - 7.3 7.3 32.9 1.5 9.5 0.3 5.4 4 1 1 5 5 5 0 SlyX Filament PF00038.21 XP_666696.1 - 8.2 5.9 54.3 0.02 14.5 26.9 3.2 2 1 0 3 3 3 0 Intermediate filament protein Peptidase_C1 PF00112.23 XP_666697.1 - 1.8e-68 230.9 2.2 3.3e-68 230.0 2.2 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 XP_666697.1 - 2.1e-13 50.5 11.7 2.2e-13 50.4 10.2 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 XP_666697.1 - 1.2e-10 40.7 0.9 1.3e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Insulin_TMD PF17870.1 XP_666697.1 - 0.024 14.7 0.3 0.054 13.6 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 6PF2K PF01591.18 XP_666697.1 - 0.036 13.4 2.0 0.067 12.5 2.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Sigma_reg_N PF13800.6 XP_666697.1 - 0.33 11.3 2.7 0.79 10.1 1.9 2.0 1 1 1 2 2 2 0 Sigma factor regulator N-terminal DUF4519 PF15012.6 XP_666697.1 - 4.5 7.5 5.4 0.68 10.1 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 4HB_MCP_1 PF12729.7 XP_666697.1 - 6.9 6.2 9.2 4.9 6.7 2.4 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CRT-like PF08627.10 XP_666698.1 - 2.6e-113 378.4 21.9 3.1e-113 378.1 21.9 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 XP_666698.1 - 9.3e-06 25.9 27.3 0.0074 16.5 12.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family UAA PF08449.11 XP_666698.1 - 0.00051 19.3 23.7 0.0012 18.1 23.7 1.5 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 XP_666698.1 - 0.065 12.7 10.8 0.043 13.3 6.8 2.2 2 0 0 2 2 2 0 Solute carrier family 35 DUF3098 PF11297.8 XP_666698.1 - 1.6 8.4 6.5 4.5 6.9 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) zf-CCCH_2 PF14608.6 XP_666699.1 - 0.02 15.3 17.5 0.044 14.3 3.2 3.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 XP_666699.1 - 0.12 12.5 9.7 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 Zinc finger domain RRM_1 PF00076.22 XP_666700.1 - 3e-37 126.3 0.0 3e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 XP_666700.1 - 0.0067 16.5 0.1 1.9 8.6 0.0 2.6 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 XP_666700.1 - 0.026 14.6 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 XP_666700.1 - 0.035 14.2 0.0 13 5.9 0.0 2.7 2 1 1 3 3 3 0 RNA recognition motif DUF4944 PF16302.5 XP_666700.1 - 0.04 14.0 0.5 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4944) RRM_Rrp7 PF17799.1 XP_666700.1 - 0.16 11.8 0.0 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain TPR_19 PF14559.6 XP_666701.1 - 5.2e-09 36.5 0.6 0.00069 20.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 XP_666701.1 - 3.8e-07 29.7 11.0 0.71 9.8 0.5 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 XP_666701.1 - 4.7e-06 26.8 5.3 6.7 7.1 0.2 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_666701.1 - 2.8e-05 23.9 22.0 3.2 8.1 0.5 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_666701.1 - 4.5e-05 23.6 9.0 0.2 11.9 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 XP_666701.1 - 0.00013 22.6 0.0 0.63 10.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 XP_666701.1 - 0.00013 22.5 0.0 17 6.5 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 XP_666701.1 - 0.00023 20.9 0.2 15 5.9 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_666701.1 - 0.00031 20.7 10.0 6.5 7.2 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat GLTP PF08718.11 XP_666701.1 - 0.14 12.5 2.9 1.3 9.3 3.4 2.4 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) TPR_6 PF13174.6 XP_666701.1 - 0.78 10.5 5.6 67 4.4 0.0 5.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Mucin PF01456.17 XP_666704.1 - 0.00062 19.8 52.9 0.0013 18.7 52.9 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein BAT2_N PF07001.11 XP_666704.1 - 0.0046 17.5 8.1 0.0088 16.5 8.1 1.4 1 0 0 1 1 1 1 BAT2 N-terminus PAN_4 PF14295.6 XP_666704.1 - 0.071 13.0 0.8 0.21 11.5 0.8 1.7 1 0 0 1 1 1 0 PAN domain Bd3614-deam PF14439.6 XP_666704.1 - 2 8.5 7.9 0.41 10.7 3.3 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase AJAP1_PANP_C PF15298.6 XP_666704.1 - 2 8.6 30.1 4.8 7.3 30.1 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Med13_C PF06333.12 XP_666704.1 - 4.4 6.5 15.9 7.5 5.7 15.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain UME PF08064.13 XP_666706.1 - 0.00031 20.6 0.2 0.49 10.3 0.0 3.8 3 0 0 3 3 3 2 UME (NUC010) domain Cnd3 PF12719.7 XP_666706.1 - 0.0038 16.5 0.2 0.014 14.6 0.2 2.0 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Bac_RepA_C PF18008.1 XP_666706.1 - 0.052 13.9 0.7 0.92 9.9 0.1 2.9 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain DUF3361 PF11841.8 XP_666706.1 - 7.6 6.5 17.1 13 5.7 0.4 6.6 6 2 0 6 6 6 0 Domain of unknown function (DUF3361) zf-Tim10_DDP PF02953.15 XP_666707.1 - 4.8e-14 51.8 1.1 6.6e-14 51.3 1.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HCO3_cotransp PF00955.21 XP_666708.1 - 1.6 7.5 3.7 0.34 9.7 0.1 1.6 2 0 0 2 2 2 0 HCO3- transporter family RapH_N PF18801.1 XP_666709.1 - 0.099 12.7 2.4 0.37 10.9 0.9 2.5 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF4302 PF14135.6 XP_666709.1 - 0.57 10.0 8.2 0.35 10.7 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4302) Helicase_C PF00271.31 XP_666710.1 - 1.8e-20 73.3 0.0 6.8e-18 65.0 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 XP_666710.1 - 9.6e-17 61.3 0.0 3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 XP_666710.1 - 8.4e-14 52.1 1.7 8.4e-14 52.1 1.7 3.2 3 0 0 3 3 3 1 RecQ zinc-binding HRDC PF00570.23 XP_666710.1 - 1.6e-06 28.0 0.0 3.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Terminase_4 PF05119.12 XP_666710.1 - 0.3 11.6 3.0 44 4.6 0.1 3.7 3 0 0 3 3 3 0 Phage terminase, small subunit DUF1788 PF08747.11 XP_666712.1 - 0.039 14.0 0.5 4.2 7.4 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) DUF4776 PF16003.5 XP_666713.1 - 0.11 11.5 22.6 0.14 11.2 22.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) WD40 PF00400.32 XP_666714.1 - 8.4e-25 86.6 11.3 0.00052 20.8 0.4 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 XP_666714.1 - 1.3e-05 25.1 4.9 0.032 14.1 0.1 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 XP_666714.1 - 0.0001 22.5 0.8 2.6 8.4 0.0 4.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_666714.1 - 0.022 14.1 2.8 0.065 12.6 2.8 2.1 1 1 0 1 1 1 0 WD40-like domain zf-RING_2 PF13639.6 XP_666715.1 - 1.3e-07 31.8 13.1 2.7e-07 30.8 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 XP_666715.1 - 5.5e-06 26.6 11.9 1.2e-05 25.5 11.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 XP_666715.1 - 0.00031 20.7 11.2 0.00055 19.8 11.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 XP_666715.1 - 0.00036 20.1 12.0 0.00077 19.0 12.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 XP_666715.1 - 0.00058 19.7 11.2 0.0015 18.4 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 XP_666715.1 - 0.00065 19.7 10.5 0.0012 18.9 10.5 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-C3HC4_2 PF13923.6 XP_666715.1 - 0.00083 19.1 15.5 0.0029 17.4 15.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 XP_666715.1 - 0.0039 17.2 5.4 0.0096 16.0 5.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 XP_666715.1 - 0.0056 16.5 11.6 0.016 15.1 11.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_666715.1 - 0.012 15.4 11.1 0.022 14.6 11.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 XP_666715.1 - 0.045 13.8 8.4 0.1 12.7 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 XP_666715.1 - 0.42 10.4 15.6 0.072 12.8 10.5 2.4 2 1 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 XP_666715.1 - 1.5 9.0 10.3 5.6 7.2 10.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 XP_666715.1 - 5.2 7.1 11.3 9.5 6.2 11.3 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 XP_666715.1 - 5.4 7.2 11.3 11 6.3 11.3 1.5 1 0 0 1 1 1 0 RING-variant domain KIAA1430 PF13879.6 XP_666716.1 - 1.1 10.1 8.4 6 7.7 0.2 3.2 2 1 1 3 3 3 0 KIAA1430 homologue CDC50 PF03381.15 XP_666717.1 - 5.8e-28 98.2 6.8 5.8e-28 98.2 6.8 1.8 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family US10 PF17617.2 XP_666718.1 - 0.037 14.1 1.6 0.25 11.4 0.4 2.4 2 0 0 2 2 2 0 Viral unique short region 10 DDRGK PF09756.9 XP_666719.1 - 5.9e-32 110.8 21.3 8.2e-32 110.3 21.3 1.2 1 0 0 1 1 1 1 DDRGK domain Hydrolase_3 PF08282.12 XP_666720.1 - 3.9e-31 108.7 0.1 7.3e-30 104.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 XP_666720.1 - 1.6e-07 31.1 0.0 1.6e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 XP_666720.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 XP_666720.1 - 0.061 13.4 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SpoU_methylase PF00588.19 XP_666721.1 - 1.7e-26 93.1 0.0 3.2e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family tRNA-synt_2b PF00587.25 XP_666722.1 - 4.8e-33 114.6 0.1 5.7e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 XP_666722.1 - 1.5e-19 69.9 0.1 4.5e-19 68.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 XP_666722.1 - 2.4e-11 43.5 0.3 7.5e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 XP_666722.1 - 2.5e-08 33.8 0.0 2.4e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 TGS domain Histone PF00125.24 XP_666723.1 - 4.3e-16 59.5 0.3 6.1e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 XP_666723.1 - 0.00038 20.7 0.0 0.00077 19.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 XP_666723.1 - 0.0013 19.2 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Rad51 PF08423.11 XP_666724.1 - 9e-119 395.4 0.0 1.4e-118 394.8 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 XP_666724.1 - 8e-11 41.9 0.3 1.2e-10 41.4 0.3 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 XP_666724.1 - 6.7e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 XP_666724.1 - 1.5e-06 28.7 1.0 3.4e-06 27.6 1.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA PF00004.29 XP_666724.1 - 0.00057 20.3 0.5 0.0043 17.5 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 XP_666724.1 - 0.0021 17.4 2.0 0.0023 17.3 0.3 2.0 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.15 XP_666724.1 - 0.02 14.6 0.5 0.041 13.6 0.5 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.23 XP_666724.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_3 PF12836.7 XP_666724.1 - 0.069 13.4 0.2 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif CPL PF08144.11 XP_666724.1 - 0.073 13.4 0.0 9.2 6.6 0.1 2.5 2 1 0 2 2 2 0 CPL (NUC119) domain HHH_6 PF14579.6 XP_666724.1 - 0.14 12.5 0.4 2.9 8.2 0.1 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ras PF00071.22 XP_666725.1 - 2.5e-17 63.0 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Ras family IBN_N PF03810.19 XP_666726.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain AP2 PF00847.20 XP_666729.1 - 9.8e-05 22.5 2.2 9.8e-05 22.5 2.2 2.2 2 0 0 2 2 2 1 AP2 domain ADAM_spacer1 PF05986.14 XP_666732.1 - 0.055 13.5 0.8 0.11 12.6 0.8 1.4 1 0 0 1 1 1 0 ADAM-TS Spacer 1 FapA PF03961.13 XP_666735.1 - 0.31 9.6 1.8 0.52 8.9 1.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PITH PF06201.13 XP_666736.1 - 8.8e-18 65.0 0.3 1e-17 64.8 0.3 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 XP_666736.1 - 0.0061 16.6 0.1 0.0099 15.9 0.1 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal CHD5 PF04420.14 XP_666737.1 - 4.5e-05 23.4 0.8 7.8e-05 22.6 0.8 1.4 1 0 0 1 1 1 1 CHD5-like protein EF-hand_6 PF13405.6 XP_666738.1 - 0.00078 19.2 0.3 0.0072 16.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 XP_666738.1 - 0.0044 16.5 0.1 0.052 13.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 XP_666738.1 - 0.009 15.8 0.5 0.07 13.0 0.5 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 XP_666738.1 - 0.028 14.9 0.8 0.028 14.9 0.8 2.1 2 0 0 2 2 2 0 EF-hand domain pair FAM104 PF15434.6 XP_666739.1 - 4.4 7.9 8.4 0.31 11.6 0.7 2.6 2 1 1 3 3 3 0 Family 104 Helicase_C PF00271.31 XP_666740.1 - 3e-11 43.6 7.0 1.7e-10 41.2 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 XP_666740.1 - 2.1e-06 28.0 0.0 5.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 XP_666740.1 - 6.1e-06 26.5 0.0 6.1e-06 26.5 0.0 4.8 4 1 0 4 4 4 1 Helicase associated domain (HA2) DEAD PF00270.29 XP_666740.1 - 1.1e-05 25.3 0.1 3.6e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 XP_666740.1 - 0.0025 18.1 0.1 0.011 16.0 0.1 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 XP_666740.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 XP_666740.1 - 0.018 15.2 0.0 0.072 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 XP_666740.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 XP_666740.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 XP_666740.1 - 0.72 10.2 3.4 0.93 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain IMCp PF12314.8 XP_666741.1 - 3.6e-17 62.4 66.8 1.2e-10 41.5 22.5 6.7 1 1 5 6 6 6 3 Inner membrane complex protein Metallophos PF00149.28 XP_666742.1 - 1.7e-28 100.5 0.2 2.1e-28 100.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 XP_666742.1 - 0.00048 20.5 1.5 0.0016 18.8 1.5 1.9 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TIR_3 PF18567.1 XP_666742.1 - 0.02 14.9 0.2 0.039 13.9 0.2 1.4 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain DUF4279 PF14106.6 XP_666742.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Ost4 PF10215.9 XP_666744.1 - 0.04 13.7 0.6 0.072 12.9 0.6 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase EF-hand_13 PF17958.1 XP_666745.1 - 7.4e-13 48.1 0.5 6.4e-12 45.1 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 XP_666745.1 - 1.5e-10 41.4 14.1 8.5e-09 35.7 10.7 3.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 XP_666745.1 - 1.5e-05 24.6 4.3 0.0076 16.1 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 XP_666745.1 - 0.048 13.2 9.3 1.5 8.6 0.2 4.4 5 0 0 5 5 5 0 EF hand zf-RING_4 PF14570.6 XP_666746.1 - 4.1e-20 71.3 16.7 1.2e-19 69.8 16.7 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 XP_666746.1 - 1.1e-08 34.7 1.1 1.9e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 XP_666746.1 - 5.1e-07 29.4 9.6 1.5e-06 28.0 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_666746.1 - 0.0026 18.0 11.6 0.0085 16.4 11.6 2.0 1 0 0 1 1 1 1 Ring finger domain RRM_5 PF13893.6 XP_666746.1 - 0.0085 15.7 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 XP_666746.1 - 0.086 12.7 9.4 2.9 7.8 9.4 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 XP_666746.1 - 7.4 6.5 12.9 23 4.9 12.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fumble PF03630.14 XP_666747.1 - 4.1e-45 154.4 5.6 4.9e-45 154.2 5.6 1.1 1 0 0 1 1 1 1 Fumble DUF3924 PF13062.6 XP_666747.1 - 0.029 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Aldedh PF00171.22 XP_666748.1 - 1.4e-14 53.4 0.0 7.7e-09 34.6 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Alg14 PF08660.11 XP_666749.1 - 1.9e-34 119.1 0.0 2.3e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ABC_tran PF00005.27 XP_666750.1 - 6.2e-32 111.0 0.3 1.4e-20 74.2 0.0 3.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 XP_666750.1 - 1.1e-14 54.7 14.3 1.1e-14 54.7 14.3 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 XP_666750.1 - 1e-06 28.4 4.1 0.082 12.3 0.0 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 XP_666750.1 - 3e-06 27.3 0.0 0.018 15.1 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 XP_666750.1 - 9.5e-06 25.6 0.3 0.018 15.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 XP_666750.1 - 4.8e-05 23.0 0.6 0.034 13.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 XP_666750.1 - 0.00012 22.5 0.1 0.021 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 XP_666750.1 - 0.00057 19.0 0.1 0.086 11.9 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 XP_666750.1 - 0.00072 19.1 0.2 0.077 12.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 XP_666750.1 - 0.0015 18.1 0.8 0.65 9.6 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 XP_666750.1 - 0.0021 17.9 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 XP_666750.1 - 0.0031 17.8 0.3 2.7 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 XP_666750.1 - 0.0032 17.2 0.3 3.8 7.3 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 XP_666750.1 - 0.014 15.4 1.8 1.9 8.5 0.1 2.9 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 XP_666750.1 - 0.088 12.7 1.8 4.2 7.2 0.0 3.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AIG1 PF04548.16 XP_666750.1 - 0.11 11.9 1.1 4.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AIG1 family NTPase_1 PF03266.15 XP_666750.1 - 0.13 12.2 1.1 23 4.8 0.0 2.8 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 XP_666750.1 - 0.14 11.4 0.1 11 5.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 XP_666750.1 - 0.17 10.8 0.4 3.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 XP_666750.1 - 0.21 10.8 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 XP_666750.1 - 0.26 11.7 2.7 6.5 7.2 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Roc PF08477.13 XP_666750.1 - 0.27 11.5 2.6 46 4.2 0.0 3.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 XP_666750.1 - 0.39 10.9 1.3 4.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 XP_666750.1 - 0.47 11.0 4.7 24 5.5 0.0 3.5 4 0 0 4 4 3 0 AAA domain MobB PF03205.14 XP_666750.1 - 0.5 10.3 1.4 17 5.3 0.6 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 XP_666750.1 - 0.69 10.0 5.8 0.32 11.1 1.0 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 XP_666750.1 - 0.75 9.7 3.8 17 5.3 0.0 3.2 3 0 0 3 3 3 0 NACHT domain Nop PF01798.18 XP_666751.1 - 4.8e-81 271.6 0.6 1.1e-80 270.5 0.6 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 XP_666751.1 - 2.3e-11 43.9 0.0 2.3e-11 43.9 0.0 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain ALMT PF11744.8 XP_666751.1 - 8.2 5.1 7.1 16 4.1 7.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter RP-C_C PF11800.8 XP_666751.1 - 8.7 6.4 7.7 16 5.5 7.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-GRF PF06839.12 XP_666752.1 - 6.2e-11 42.2 3.3 1.6e-10 40.9 3.3 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos PF03372.23 XP_666752.1 - 5.5e-10 39.2 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 XP_666752.1 - 2.1e-06 27.6 3.9 0.0083 16.0 0.0 3.3 4 0 0 4 4 4 2 Endonuclease-reverse transcriptase Swi6_N PF18530.1 XP_666752.1 - 0.054 13.6 3.6 0.68 10.1 0.1 2.5 1 1 1 2 2 2 0 Swi6 N-terminal domain Aminotran_5 PF00266.19 XP_666753.1 - 3.4e-35 121.7 0.0 5.9e-35 120.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V HSP70 PF00012.20 XP_666754.1 - 1.4e-262 872.2 5.8 1.6e-262 872.1 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 XP_666754.1 - 4.3e-16 58.6 0.1 2.7e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 XP_666754.1 - 0.033 13.2 0.3 0.34 9.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 XP_666754.1 - 0.048 12.9 0.3 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF494 PF04361.13 XP_666754.1 - 0.074 12.9 0.6 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) MutS_III PF05192.18 XP_666754.1 - 0.077 13.2 3.6 2.3 8.4 2.2 2.2 2 0 0 2 2 2 0 MutS domain III PKK PF12474.8 XP_666754.1 - 0.14 12.3 15.8 0.19 11.8 11.7 2.3 2 0 0 2 2 2 0 Polo kinase kinase DUF515 PF04415.12 XP_666754.1 - 0.19 10.1 5.5 0.3 9.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RRP7 PF12923.7 XP_666755.1 - 0.0067 16.6 1.3 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain KCNQ2_u3 PF16642.5 XP_666755.1 - 3.5 8.7 11.9 0.74 10.8 3.0 2.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PPR_1 PF12854.7 XP_666756.1 - 0.59 9.9 0.0 0.59 9.9 0.0 2.4 3 0 0 3 3 3 0 PPR repeat cwf21 PF08312.12 XP_666757.1 - 0.00063 19.8 5.6 0.002 18.2 5.6 1.9 1 0 0 1 1 1 1 cwf21 domain zf-CCCH PF00642.24 XP_666758.1 - 2e-17 62.7 11.3 2.8e-07 30.3 0.9 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 XP_666758.1 - 6.7e-10 38.5 14.1 5.4e-05 22.9 2.1 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 XP_666758.1 - 1.3e-07 31.4 17.4 3.5e-05 23.7 3.0 4.0 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 XP_666758.1 - 8.8e-06 25.9 9.5 0.00028 21.1 2.6 3.0 2 1 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 XP_666758.1 - 7e-05 23.5 14.4 0.0002 22.0 0.9 4.0 3 1 2 5 5 5 2 Torus domain zf-CCCH_2 PF14608.6 XP_666758.1 - 0.16 12.5 14.9 0.53 10.8 0.6 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Bromodomain PF00439.25 XP_666759.1 - 2.7e-22 78.6 1.5 2.7e-22 78.6 1.5 1.8 2 0 0 2 2 2 1 Bromodomain RRN3 PF05327.11 XP_666759.1 - 0.23 10.0 3.8 0.33 9.4 3.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 XP_666759.1 - 5 5.3 14.5 8.9 4.5 14.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Filament PF00038.21 XP_666760.1 - 0.002 17.7 22.4 0.002 17.7 22.4 2.0 2 0 0 2 2 2 1 Intermediate filament protein Sec34 PF04136.15 XP_666760.1 - 0.026 14.4 3.9 0.026 14.4 3.9 3.0 3 1 0 3 3 3 0 Sec34-like family APG6_N PF17675.1 XP_666760.1 - 0.038 14.5 31.6 1.7 9.1 9.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 XP_666760.1 - 0.046 14.2 8.8 4 8.0 0.1 3.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 XP_666760.1 - 0.21 11.6 36.5 0.025 14.5 10.8 3.8 2 1 2 4 4 4 0 FlxA-like protein ATG16 PF08614.11 XP_666760.1 - 0.22 11.7 31.9 2 8.6 10.1 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 XP_666760.1 - 1.3 7.9 36.9 0.072 12.0 14.5 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 XP_666760.1 - 2.3 8.9 22.6 7.2 7.3 2.3 4.3 2 1 1 4 4 4 0 SlyX 4HB_MCP_1 PF12729.7 XP_666760.1 - 3.4 7.2 18.8 2.4 7.7 5.8 2.3 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TMF_TATA_bd PF12325.8 XP_666760.1 - 3.6 7.8 31.0 0.18 12.0 9.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Phage_GPO PF05929.11 XP_666760.1 - 3.8 7.1 18.2 3 7.4 5.8 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 XP_666760.1 - 5.3 6.3 19.7 53 3.0 19.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Glycos_transf_1 PF00534.20 XP_666762.1 - 3.3e-37 127.6 0.0 5.3e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 XP_666762.1 - 8.1e-27 94.3 0.0 1.4e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 XP_666762.1 - 9.8e-23 81.0 0.2 5.4e-22 78.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 XP_666762.1 - 4.8e-18 66.1 0.0 1.7e-17 64.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 XP_666762.1 - 4.3e-15 56.1 0.0 1.5e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase_C PF02806.18 XP_666762.1 - 1.4e-05 25.5 0.1 5.7e-05 23.5 0.1 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 XP_666762.1 - 4e-05 23.3 0.0 0.00018 21.2 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_2 PF13524.6 XP_666762.1 - 0.011 16.2 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 TPT PF03151.16 XP_666763.1 - 4.4e-23 82.0 25.4 5.6e-23 81.7 25.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 XP_666763.1 - 1.3e-08 35.1 33.9 2.7e-06 27.6 12.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 XP_666763.1 - 1e-07 31.5 27.7 3.6e-07 29.7 27.4 1.8 1 1 0 1 1 1 1 UAA transporter family Peptidase_M16 PF00675.20 XP_666764.1 - 1.5e-45 154.9 0.0 2.4e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_666764.1 - 1.6e-14 54.4 0.2 5.8e-13 49.2 0.2 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF725 PF05267.12 XP_666764.1 - 0.028 14.4 0.2 0.082 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF725) LOH1CR12 PF10158.9 XP_666764.1 - 0.053 13.5 0.0 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Tumour suppressor protein Maf1 PF09174.10 XP_666767.1 - 9.9e-36 123.5 3.4 1.5e-35 122.9 3.4 1.3 1 1 0 1 1 1 1 Maf1 regulator CCDC14 PF15254.6 XP_666768.1 - 7 5.2 7.6 8.7 4.8 7.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Rhomboid PF01694.22 XP_666769.1 - 3.4e-25 88.8 16.5 3.4e-25 88.8 16.5 1.7 2 0 0 2 2 2 1 Rhomboid family Chibby PF14645.6 XP_666769.1 - 0.11 13.0 1.5 0.14 12.6 0.2 1.7 2 0 0 2 2 2 0 Chibby family HEAT_EZ PF13513.6 XP_666770.1 - 1.7e-12 47.5 5.0 1.6e-06 28.4 0.0 7.9 7 1 1 8 8 8 1 HEAT-like repeat HEAT PF02985.22 XP_666770.1 - 1.3e-08 34.4 16.0 0.0016 18.5 0.0 8.9 11 1 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.7 XP_666770.1 - 1.1e-06 29.1 0.1 0.07 13.7 0.0 3.3 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 XP_666770.1 - 2.5e-06 27.3 3.2 3.5e-06 26.8 0.4 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 XP_666770.1 - 0.00041 20.4 0.6 0.03 14.4 0.0 3.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 XP_666770.1 - 0.03 13.9 0.1 13 5.2 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal mRNA_stabil PF13929.6 XP_666770.1 - 0.12 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 mRNA stabilisation Arm PF00514.23 XP_666770.1 - 0.69 10.1 7.7 15 5.8 0.3 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Peptidase_M60_C PF18630.1 XP_666771.1 - 0.089 12.9 0.2 0.31 11.2 0.2 1.9 1 0 0 1 1 1 0 Peptidase M60 C-terminal domain Pkinase PF00069.25 XP_666772.1 - 5e-42 144.1 0.2 5e-42 144.1 0.2 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666772.1 - 2.4e-11 43.4 0.0 4.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EMC3_TMCO1 PF01956.16 XP_666773.1 - 7.1e-15 55.2 2.9 8.2e-15 55.0 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EMC3_TMCO1 PF01956.16 XP_666774.1 - 0.00038 20.2 0.0 0.0022 17.8 0.0 1.9 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SNF2_N PF00176.23 XP_666775.1 - 2.5e-67 227.1 0.3 5.3e-67 226.0 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_666775.1 - 1.9e-17 63.6 0.0 9.7e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SLIDE PF09111.10 XP_666775.1 - 0.0065 16.5 0.5 0.0065 16.5 0.5 3.2 3 0 0 3 3 3 1 SLIDE Myb_DNA-binding PF00249.31 XP_666775.1 - 0.034 14.3 1.6 1.5 9.1 0.0 3.6 2 1 1 3 3 3 0 Myb-like DNA-binding domain Astro_capsid_p PF12226.8 XP_666775.1 - 6.3 5.9 15.7 0.038 13.1 7.0 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein PABP PF00658.18 XP_666776.1 - 0.078 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain Zn_Tnp_IS91 PF14319.6 XP_666777.1 - 0.1 12.7 0.6 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain Prefoldin_3 PF13758.6 XP_666778.1 - 0.014 15.5 1.2 0.018 15.1 1.2 1.4 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 XP_666778.1 - 0.068 13.4 1.8 0.53 10.5 0.6 2.1 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 XP_666778.1 - 0.088 13.1 1.1 0.088 13.1 1.1 1.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain FRB_dom PF08771.11 XP_666780.1 - 0.16 12.4 3.8 3.3 8.2 0.2 2.8 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain DUF5101 PF17031.5 XP_666780.1 - 4.5 7.4 9.1 0.25 11.5 1.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5101) GST_C_3 PF14497.6 XP_666781.1 - 5.3e-07 29.8 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 XP_666781.1 - 0.0026 18.0 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3467 PF11950.8 XP_666783.1 - 0.0042 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3467) SNF2_N PF00176.23 XP_666784.1 - 1.2e-64 218.3 0.4 1.2e-64 218.3 0.4 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 XP_666784.1 - 1.9e-10 41.0 0.0 6.6e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_666784.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase BRCT_2 PF16589.5 XP_666785.1 - 5e-06 26.8 5.5 0.043 14.2 2.7 3.2 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 XP_666785.1 - 0.0053 16.8 0.2 0.73 9.9 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 XP_666785.1 - 0.0095 16.3 5.7 0.26 11.7 0.0 3.7 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain TBPIP PF07106.13 XP_666787.1 - 3.6e-24 84.5 0.8 7.1e-24 83.5 0.8 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain TFIIE_beta PF02186.15 XP_666787.1 - 0.0045 17.2 0.9 0.22 11.9 0.0 2.6 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF4777 PF16007.5 XP_666787.1 - 0.047 13.9 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) YL1 PF05764.13 XP_666787.1 - 7 6.7 33.7 12 5.9 32.7 1.9 1 1 0 1 1 1 0 YL1 nuclear protein Mito_carr PF00153.27 XP_666788.1 - 8.4e-32 109.0 2.1 7.5e-16 57.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5359 PF17313.2 XP_666788.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5359) Proteasome PF00227.26 XP_666789.1 - 1.9e-38 131.9 0.0 2.2e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Solute_trans_a PF03619.16 XP_666790.1 - 5.7e-09 35.9 21.2 9.2e-09 35.2 21.2 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2465 PF10239.9 XP_666790.1 - 0.42 9.8 2.5 0.77 8.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) DUF2976 PF11190.8 XP_666790.1 - 1.4 8.8 5.5 0.93 9.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) PQ-loop PF04193.14 XP_666791.1 - 1.3e-20 73.0 20.9 1.7e-11 43.7 8.8 2.7 2 1 0 2 2 2 2 PQ loop repeat Nucleos_tra2_N PF01773.20 XP_666791.1 - 6.7 7.4 8.5 0.35 11.5 0.9 2.7 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus LRR_9 PF14580.6 XP_666792.1 - 2e-34 118.6 5.1 2.1e-34 118.5 5.1 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 XP_666792.1 - 2.7e-09 37.2 24.3 0.00015 22.1 1.6 4.1 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 XP_666792.1 - 7.4e-08 32.0 14.5 3.6e-06 26.6 7.0 3.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 XP_666792.1 - 0.18 12.4 11.5 4 8.4 0.4 4.4 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 XP_666792.1 - 0.26 11.4 7.5 14 6.1 0.6 3.9 3 0 0 3 3 3 0 Leucine Rich repeat PROCN PF08083.11 XP_666793.1 - 6.7e-219 726.6 10.0 1.2e-218 725.8 10.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 XP_666793.1 - 9.7e-124 411.5 1.3 2e-123 410.4 1.3 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 XP_666793.1 - 7.8e-88 292.4 3.2 2.1e-87 291.0 3.2 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 XP_666793.1 - 5.3e-79 263.5 0.7 1.7e-78 261.9 0.7 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 XP_666793.1 - 9.5e-69 229.6 0.1 2.3e-68 228.4 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 XP_666793.1 - 4.6e-45 151.9 0.6 1.5e-44 150.2 0.6 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 XP_666793.1 - 1.4e-18 67.0 0.2 2.9e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain Pkinase_Tyr PF07714.17 XP_666794.1 - 5.3e-44 150.4 0.0 6.6e-43 146.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 XP_666794.1 - 5.1e-43 147.3 0.0 2.4e-40 138.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 XP_666794.1 - 0.064 12.0 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase PVL_ORF50 PF07768.11 XP_666794.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family Peptidase_C54 PF03416.19 XP_666796.1 - 3e-40 138.4 0.6 3.5e-40 138.2 0.6 1.1 1 0 0 1 1 1 1 Peptidase family C54 Tim44 PF04280.15 XP_666797.1 - 3.4e-23 82.4 0.0 1.8e-21 76.8 0.0 2.4 1 1 0 1 1 1 1 Tim44-like domain PLDc_2 PF13091.6 XP_666798.1 - 2.6e-33 114.7 2.9 6e-16 58.5 0.2 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 XP_666798.1 - 6.8e-06 26.0 0.6 0.0031 17.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Chrome_Resist PF09828.9 XP_666798.1 - 0.01 16.3 0.2 0.023 15.1 0.2 1.6 1 1 0 1 1 1 0 Chromate resistance exported protein Pan3_PK PF18101.1 XP_666798.1 - 0.031 14.2 0.8 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Pan3 Pseudokinase domain KH_8 PF17903.1 XP_666799.1 - 9.4e-33 112.2 3.0 1.2e-32 111.8 0.0 2.5 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 XP_666799.1 - 0.00066 19.5 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 KH domain Nod1 PF17114.5 XP_666800.1 - 0.014 15.6 2.1 0.014 15.6 2.1 2.6 3 1 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 FAM76 PF16046.5 XP_666802.1 - 4.4e-32 111.6 41.2 6.1e-32 111.2 41.2 1.2 1 0 0 1 1 1 1 FAM76 protein Peptidase_S76 PF13611.6 XP_666802.1 - 0.012 16.0 2.3 0.014 15.7 0.3 2.2 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 HAUS-augmin3 PF14932.6 XP_666802.1 - 1.6 8.2 21.2 0.098 12.2 3.7 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Dynamin_M PF01031.20 XP_666804.1 - 5.4e-59 199.7 0.9 4.2e-58 196.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 XP_666804.1 - 1.8e-27 95.3 2.6 3.8e-27 94.3 2.6 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain Peroxin-22 PF12827.7 XP_666804.1 - 0.016 15.1 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family GDPD_2 PF13653.6 XP_666804.1 - 0.09 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Dynamin_N PF00350.23 XP_666805.1 - 7.5e-05 22.9 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Ras PF00071.22 XP_666805.1 - 0.0024 17.5 0.1 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 XP_666805.1 - 0.008 16.3 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 XP_666805.1 - 0.011 15.9 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 XP_666805.1 - 0.083 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 XP_666806.1 - 2.1e-77 258.5 0.2 2.4e-77 258.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 XP_666806.1 - 1.1e-14 54.6 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 XP_666806.1 - 1.1e-13 51.1 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 XP_666806.1 - 5.8e-13 48.7 0.0 7.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 XP_666806.1 - 2.7e-12 46.5 0.7 3.2e-08 33.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 XP_666806.1 - 3.2e-09 36.5 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 XP_666806.1 - 7.9e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 XP_666806.1 - 0.0082 15.5 0.1 0.017 14.5 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 XP_666806.1 - 0.015 14.9 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 XP_666806.1 - 0.025 14.5 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 XP_666806.1 - 0.042 13.4 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PDCD2_C PF04194.13 XP_666807.1 - 1.8e-28 99.8 0.0 2.1e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain zf-H2C2_2 PF13465.6 XP_666807.1 - 1.1 9.8 3.5 2.6 8.6 1.0 2.4 2 1 0 2 2 2 0 Zinc-finger double domain zf_C2H2_13 PF18508.1 XP_666808.1 - 0.0071 15.9 1.0 0.19 11.3 0.1 2.6 2 0 0 2 2 2 1 Zinc finger domain DZR PF12773.7 XP_666808.1 - 0.31 11.1 7.5 4.5 7.4 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon CENP-B_dimeris PF09026.10 XP_666808.1 - 6.1 7.3 11.0 11 6.5 11.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 XP_666809.1 - 6.4e-34 117.9 27.7 6.4e-34 117.9 27.7 2.4 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 XP_666809.1 - 1.1e-12 48.0 0.2 7.1e-12 45.5 0.1 2.6 2 0 0 2 2 2 1 NUC130/3NT domain SapB_1 PF05184.15 XP_666809.1 - 0.062 13.3 0.0 25 5.0 0.0 3.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF4288 PF14119.6 XP_666809.1 - 1.6 9.2 4.9 0.3 11.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DNA_pol_E_B PF04042.16 XP_666810.1 - 3.1e-34 118.2 0.4 8.9e-34 116.7 0.5 1.8 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B TF_Zn_Ribbon PF08271.12 XP_666811.1 - 1e-10 41.0 2.0 2e-10 40.0 2.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Nudix_N_2 PF14803.6 XP_666811.1 - 0.062 13.2 1.0 9.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 XP_666811.1 - 0.085 12.6 2.0 6.3 6.7 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 XP_666811.1 - 0.14 11.9 4.0 0.5 10.1 4.1 1.9 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-FPG_IleRS PF06827.14 XP_666811.1 - 1.2 9.1 4.1 21 5.1 0.3 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS cobW PF02492.19 XP_666812.1 - 4.6e-43 146.9 1.2 6.9e-43 146.3 1.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 XP_666812.1 - 0.00015 21.8 0.7 0.00035 20.6 0.5 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 XP_666812.1 - 0.00041 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 XP_666812.1 - 0.0014 18.7 0.0 0.0049 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain CobW_C PF07683.14 XP_666812.1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 XP_666812.1 - 0.0047 16.7 0.3 0.017 14.9 0.0 2.1 2 1 2 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 XP_666812.1 - 0.017 15.5 0.0 0.076 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 XP_666812.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 XP_666812.1 - 0.046 14.2 1.8 0.089 13.3 1.0 2.2 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 XP_666812.1 - 0.048 14.2 0.1 0.23 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 XP_666812.1 - 0.052 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 XP_666812.1 - 0.096 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 XP_666812.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 XP_666812.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 XP_666812.1 - 0.13 12.5 0.0 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 XP_666812.1 - 0.26 10.2 0.5 7.6 5.4 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB U3_assoc_6 PF08640.11 XP_666813.1 - 1.2e-24 86.2 5.2 1.2e-24 86.2 5.2 2.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_19 PF14559.6 XP_666813.1 - 0.12 12.9 0.0 19 5.9 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 XP_666813.1 - 0.21 12.5 0.0 65 4.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.14 XP_666814.1 - 5.5e-09 36.0 1.6 2e-07 30.9 0.5 3.3 1 1 1 2 2 2 1 Pep3/Vps18/deep orange family zf-RING_11 PF17123.5 XP_666814.1 - 0.0098 15.6 0.4 0.0098 15.6 0.4 2.5 2 0 0 2 2 2 1 RING-like zinc finger Ureide_permease PF07168.11 XP_666814.1 - 0.065 12.0 1.4 0.12 11.2 1.4 1.3 1 0 0 1 1 1 0 Ureide permease Vps39_2 PF10367.9 XP_666814.1 - 0.11 13.0 0.7 0.54 10.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 CCM2_C PF16545.5 XP_666814.1 - 0.19 12.3 2.7 2.8 8.5 0.1 3.7 3 0 0 3 3 3 0 Cerebral cavernous malformation protein, harmonin-homology zf-C3HC4_2 PF13923.6 XP_666814.1 - 0.43 10.5 3.5 0.25 11.2 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 XP_666814.1 - 0.68 10.3 2.1 1.4 9.3 0.8 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain TPR_22 PF18833.1 XP_666814.1 - 3.2 8.0 6.2 1.5 9.0 2.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UDPG_MGDP_dh_N PF03721.14 XP_666815.1 - 7.2e-60 201.8 0.2 1.4e-59 200.8 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 XP_666815.1 - 1.7e-29 101.8 0.2 5.4e-29 100.2 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 XP_666815.1 - 9.3e-29 99.9 0.0 6.9e-27 93.9 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.23 XP_666815.1 - 6.6e-07 29.4 0.0 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 XP_666815.1 - 0.0036 17.4 0.5 0.25 11.4 0.0 3.5 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 XP_666815.1 - 0.0046 17.1 0.0 0.023 14.9 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 XP_666815.1 - 0.0088 16.3 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 XP_666815.1 - 0.053 12.8 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-rbx1 PF12678.7 XP_666816.1 - 7.3e-25 87.0 12.5 7.3e-25 87.0 12.5 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 XP_666816.1 - 5.2e-18 64.9 9.8 7.4e-18 64.4 9.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 XP_666816.1 - 8.1e-07 29.3 14.1 3.3e-05 24.1 14.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 XP_666816.1 - 1.2e-05 25.0 3.4 1.2e-05 25.0 3.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_666816.1 - 0.00083 19.2 11.5 0.0055 16.5 11.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 XP_666816.1 - 0.0019 17.9 1.2 0.0019 17.9 1.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 XP_666816.1 - 0.11 12.7 9.1 1.5 9.0 9.6 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 XP_666816.1 - 0.16 12.0 7.2 0.6 10.2 7.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 XP_666816.1 - 0.3 11.0 11.7 0.81 9.6 5.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_666816.1 - 0.31 11.0 11.0 1.5 8.8 11.0 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 XP_666816.1 - 0.8 9.4 14.3 0.12 12.1 4.4 2.4 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 XP_666816.1 - 5.7 7.2 8.3 0.55 10.4 0.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING HECT PF00632.25 XP_666817.1 - 6.5e-14 52.1 0.1 8.3e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CAF1C_H4-bd PF12265.8 XP_666818.1 - 1.5e-21 76.4 0.7 4.7e-21 74.8 0.7 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 XP_666818.1 - 5.8e-17 61.7 6.8 6.8e-05 23.6 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat EF-1_beta_acid PF10587.9 XP_666819.1 - 0.17 12.4 1.5 0.17 12.4 1.5 1.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Mog1 PF04603.12 XP_666820.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein zf-RING_2 PF13639.6 XP_666821.1 - 7.2e-12 45.5 7.3 1.4e-11 44.5 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 XP_666821.1 - 5.9e-08 32.3 5.7 1.5e-07 31.0 5.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 XP_666821.1 - 6.5e-08 32.7 6.9 1.2e-07 31.9 6.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 XP_666821.1 - 1.6e-06 27.9 6.9 3e-06 27.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_666821.1 - 4.1e-06 26.6 6.3 8.7e-06 25.5 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_666821.1 - 7.5e-06 25.8 5.1 1.6e-05 24.8 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 XP_666821.1 - 2e-05 24.5 3.6 4.4e-05 23.4 3.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 XP_666821.1 - 2e-05 24.1 6.9 7e-05 22.4 7.0 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 XP_666821.1 - 8.3e-05 22.4 3.1 0.00014 21.6 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 XP_666821.1 - 0.0013 18.7 2.6 0.0027 17.7 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 XP_666821.1 - 0.0077 16.4 2.3 0.0077 16.4 2.3 2.1 1 1 1 2 2 2 1 Zinc-ribbon like family zf-C3H2C3 PF17122.5 XP_666821.1 - 0.014 15.4 2.8 0.043 13.9 2.8 1.9 1 0 0 1 1 1 0 Zinc-finger CDC48_2 PF02933.17 XP_666821.1 - 0.045 13.5 0.0 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 Prok-RING_4 PF14447.6 XP_666821.1 - 0.054 13.4 8.0 0.065 13.1 6.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 XP_666821.1 - 0.062 13.4 4.1 0.15 12.2 3.5 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 PHD PF00628.29 XP_666821.1 - 0.22 11.4 5.9 0.56 10.1 5.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 XP_666821.1 - 0.24 11.8 6.3 0.62 10.4 6.3 1.8 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 XP_666821.1 - 0.3 11.3 6.1 1 9.6 6.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 XP_666821.1 - 1.2 9.3 9.2 0.71 10.0 7.0 1.8 2 0 0 2 2 1 0 RING-variant domain Prok-RING_1 PF14446.6 XP_666821.1 - 1.8 8.6 8.1 0.26 11.2 2.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 XP_666821.1 - 2.4 8.4 8.6 5.5 7.2 7.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RNA_pol_Rbc25 PF08292.12 XP_666822.1 - 3.7e-23 82.2 2.0 5.7e-18 65.4 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 XP_666822.1 - 0.0017 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 XP_666822.1 - 0.0021 18.3 0.0 0.0086 16.4 0.0 2.1 1 1 0 1 1 1 1 S1 RNA binding domain COPI_assoc PF08507.10 XP_666823.1 - 1.6e-06 28.2 6.2 2e-06 27.9 6.2 1.1 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 XP_666823.1 - 0.23 11.8 5.4 0.36 11.2 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Prenyltrans PF00432.21 XP_666824.1 - 2.4e-32 110.3 12.9 1e-10 41.1 2.8 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat DUF2093 PF09866.9 XP_666824.1 - 1.4 8.5 5.8 0.58 9.6 2.3 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Thg1C PF14413.6 XP_666825.1 - 2e-38 131.3 2.0 2.5e-38 130.9 2.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF3574 PF12098.8 XP_666825.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3574) Utp14 PF04615.13 XP_666826.1 - 3.9e-57 194.4 38.3 4.1e-32 111.7 34.3 2.2 1 1 1 2 2 2 2 Utp14 protein DinI PF06183.13 XP_666826.1 - 1.5 9.2 6.8 17 5.8 1.0 3.1 2 0 0 2 2 2 0 DinI-like family Prp19 PF08606.11 XP_666827.1 - 0.0093 15.9 0.7 0.13 12.3 0.5 2.7 2 0 0 2 2 2 1 Prp19/Pso4-like DUF4094 PF13334.6 XP_666827.1 - 0.15 12.5 0.2 0.15 12.5 0.2 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4094) Uds1 PF15456.6 XP_666827.1 - 4.8 7.4 15.1 0.15 12.2 6.1 2.9 3 0 0 3 3 3 0 Up-regulated During Septation DEAD PF00270.29 XP_666829.1 - 1.3e-34 119.4 0.0 1.9e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 XP_666829.1 - 6.7e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 XP_666829.1 - 0.028 14.7 2.0 4.9 7.4 0.2 2.8 3 1 0 3 3 3 0 AAA domain UTP25 PF06862.12 XP_666829.1 - 0.083 11.6 1.2 0.31 9.7 0.8 2.0 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Neurensin PF14927.6 XP_666830.1 - 0.0012 18.6 2.2 0.5 10.1 0.4 2.8 3 0 0 3 3 3 2 Neurensin DUF2730 PF10805.8 XP_666830.1 - 0.003 17.6 1.1 0.5 10.5 0.4 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) DUF308 PF03729.13 XP_666830.1 - 0.087 13.2 10.9 0.052 13.9 5.6 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Phage_holin_2_1 PF04971.12 XP_666830.1 - 0.09 12.8 0.7 0.32 11.0 0.7 1.9 1 0 0 1 1 1 0 Bacteriophage P21 holin S TRIQK PF15168.6 XP_666830.1 - 3.5 7.6 9.0 5.6 6.9 0.7 3.3 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF4064 PF13273.6 XP_666830.1 - 5.1 7.4 9.7 5.5 7.3 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) START PF01852.19 XP_666831.1 - 7.2e-08 32.1 0.1 3.9e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 START domain RNase_P_p30 PF01876.16 XP_666832.1 - 1.8e-52 178.0 0.1 2.2e-47 161.3 0.1 2.1 2 0 0 2 2 2 2 RNase P subunit p30 DUF866 PF05907.13 XP_666833.1 - 5.4e-39 133.6 1.8 6e-39 133.4 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) eIF2_C PF09173.11 XP_666835.1 - 1.1e-30 105.7 0.0 2.4e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 XP_666835.1 - 1.6e-23 83.2 0.8 2e-22 79.7 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 XP_666835.1 - 2.4e-11 43.9 1.3 8.7e-11 42.1 0.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 XP_666835.1 - 0.0048 17.0 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dak1_2 PF13684.6 XP_666835.1 - 0.01 14.9 0.3 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family RsgA_GTPase PF03193.16 XP_666835.1 - 0.014 15.3 0.6 0.071 13.0 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase HALZ PF02183.18 XP_666838.1 - 0.00035 20.7 7.3 0.00035 20.7 7.3 4.0 3 1 0 3 3 3 1 Homeobox associated leucine zipper DUF4164 PF13747.6 XP_666838.1 - 0.72 10.2 6.1 9.5 6.6 3.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Rootletin PF15035.6 XP_666838.1 - 4 7.4 23.5 2.1 8.4 8.1 2.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Kinesin PF00225.23 XP_666839.1 - 3.9e-94 315.3 7.8 3.9e-94 315.3 7.8 2.8 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 XP_666839.1 - 2e-22 79.7 1.0 2e-22 79.7 1.0 3.7 3 1 0 3 3 3 1 Microtubule binding Inhibitor_I42 PF09394.10 XP_666840.1 - 1.4e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 DUF2500 PF10694.9 XP_666840.1 - 0.047 14.2 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Kinesin PF00225.23 XP_666841.1 - 5.8e-65 219.4 0.2 5.8e-65 219.4 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 XP_666841.1 - 2.4e-17 63.2 0.4 7.3e-17 61.7 0.4 1.8 1 0 0 1 1 1 1 Microtubule binding MANEC PF07502.14 XP_666841.1 - 2.8 8.2 8.6 0.67 10.3 4.3 2.2 2 0 0 2 2 2 0 MANEC domain DUF1764 PF08576.10 XP_666842.1 - 5.2e-07 30.5 1.2 6.6e-07 30.2 1.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Cas_Csa5 PF09702.10 XP_666842.1 - 0.047 13.9 0.3 0.057 13.7 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) BCIP PF13862.6 XP_666843.1 - 3.7e-36 124.8 1.0 5.5e-36 124.3 1.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SRP19 PF01922.17 XP_666844.1 - 1.6e-21 77.1 0.0 2.7e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein tRNA_bind_4 PF18490.1 XP_666844.1 - 0.026 14.3 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 tRNA-binding domain DUF21 PF01595.20 XP_666845.1 - 7.3e-37 126.8 1.3 1.1e-36 126.2 1.3 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 XP_666845.1 - 0.011 16.1 0.4 6.1 7.4 0.0 3.3 2 2 1 3 3 3 0 CBS domain D123 PF07065.14 XP_666846.1 - 5.4e-34 117.7 0.7 8.6e-34 117.1 0.7 1.4 1 0 0 1 1 1 1 D123 Ribosomal_L28e PF01778.17 XP_666847.1 - 4.9e-10 40.2 0.2 5.9e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ribosomal_L29 PF00831.23 XP_666848.1 - 1.2e-17 63.6 1.8 1.2e-17 63.6 1.8 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein WD40_alt PF14077.6 XP_666848.1 - 0.13 12.1 0.7 0.28 11.1 0.7 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif SWIB PF02201.18 XP_666849.1 - 1.3e-14 53.8 0.1 3.6e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Arf PF00025.21 XP_666851.1 - 5e-78 260.5 0.1 5.7e-78 260.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 XP_666851.1 - 3.8e-14 52.9 0.0 5.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 XP_666851.1 - 1.7e-13 50.4 0.0 2.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 XP_666851.1 - 1.6e-12 47.3 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 XP_666851.1 - 5.4e-11 42.3 0.4 7.1e-07 28.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 XP_666851.1 - 5.4e-10 39.0 0.0 6.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 XP_666851.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 XP_666851.1 - 0.0098 15.2 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 XP_666851.1 - 0.044 13.3 0.1 0.12 12.0 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Flavoprotein PF02441.19 XP_666852.1 - 6.8e-30 103.9 0.1 7.6e-30 103.7 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein NAD_binding_7 PF13241.6 XP_666852.1 - 0.062 13.7 0.0 0.062 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding FtsJ PF01728.19 XP_666854.1 - 7.4e-69 231.4 0.0 8.7e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rad60-SLD PF11976.8 XP_666855.1 - 5.8e-07 29.3 0.7 1.6e-06 27.8 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndc1_Nup PF09531.10 XP_666855.1 - 0.19 10.4 0.9 0.22 10.2 0.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pox_Ag35 PF03286.14 XP_666855.1 - 0.21 11.3 11.4 0.17 11.7 10.2 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 XP_666857.1 - 3.4e-82 275.8 0.1 5.7e-82 275.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666857.1 - 4.3e-43 147.4 0.0 6.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 XP_666857.1 - 1.9e-24 85.9 9.6 1e-12 48.3 1.7 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_666857.1 - 2.8e-24 82.8 10.4 1.3e-06 27.5 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 XP_666857.1 - 5.7e-20 69.5 9.7 6.6e-07 28.8 0.4 4.9 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 XP_666857.1 - 6.5e-18 63.4 12.0 6.4e-05 22.3 0.3 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 XP_666857.1 - 1e-16 60.5 9.1 0.0013 18.5 0.0 4.5 2 1 2 4 4 4 4 EF-hand domain pair Pkinase_fungal PF17667.1 XP_666857.1 - 5.4e-07 28.7 0.0 1.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_666857.1 - 6.6e-07 28.9 0.3 1.8e-06 27.5 0.3 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 XP_666857.1 - 1.2e-05 24.8 0.0 0.028 13.7 0.0 2.7 1 1 1 2 2 2 2 Kinase-like EF-hand_4 PF12763.7 XP_666857.1 - 7.5e-05 22.6 5.3 0.31 11.0 0.4 3.7 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 XP_666857.1 - 0.00038 20.8 0.7 0.96 9.8 0.1 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region FTA2 PF13095.6 XP_666857.1 - 0.0093 15.6 0.2 4.4 6.9 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 EF-hand_9 PF14658.6 XP_666857.1 - 0.01 16.1 0.4 0.2 12.0 0.0 2.8 3 0 0 3 3 2 0 EF-hand domain YrbL-PhoP_reg PF10707.9 XP_666857.1 - 0.01 15.3 0.2 0.095 12.2 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 XP_666857.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 XP_666857.1 - 0.029 13.3 1.0 0.13 11.2 1.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain EF-hand_10 PF14788.6 XP_666857.1 - 0.36 10.7 2.1 1.5 8.8 0.0 2.9 2 1 0 2 2 2 0 EF hand DnaJ PF00226.31 XP_666859.1 - 4.7e-16 58.7 0.4 6.8e-15 54.9 0.4 2.1 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 XP_666859.1 - 5.6e-09 35.6 0.8 9.4e-09 34.9 0.8 1.4 1 0 0 1 1 1 1 CSL zinc finger DUF1363 PF07101.11 XP_666861.1 - 0.13 12.5 0.1 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) Phage_int_SAM_5 PF13102.6 XP_666861.1 - 0.14 12.5 0.3 0.53 10.6 0.2 2.1 2 0 0 2 2 2 0 Phage integrase SAM-like domain ubiquitin PF00240.23 XP_666862.1 - 0.00046 19.9 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family FucT_N PF18025.1 XP_666862.1 - 0.072 13.5 0.0 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain PhoLip_ATPase_C PF16212.5 XP_666863.1 - 1.8e-54 185.1 30.7 1.8e-54 185.1 30.7 2.1 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 XP_666863.1 - 2.8e-13 50.6 0.1 7.6e-08 32.9 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_666863.1 - 9.1e-05 22.5 0.0 0.00044 20.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 XP_666863.1 - 0.028 14.2 3.8 0.059 13.1 0.3 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ferredoxin_N PF16947.5 XP_666863.1 - 0.028 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Hydrolase_6 PF13344.6 XP_666863.1 - 0.12 12.5 0.0 0.56 10.3 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Slu7 PF11708.8 XP_666864.1 - 9.6e-68 228.8 11.4 9.6e-68 228.8 11.4 1.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 XP_666864.1 - 0.0033 17.4 2.0 0.007 16.4 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 XP_666864.1 - 0.012 15.3 0.3 0.031 14.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle NifU PF01106.17 XP_666864.1 - 0.076 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 NifU-like domain PHD PF00628.29 XP_666865.1 - 0.00037 20.3 6.5 0.0011 18.8 6.5 1.9 1 0 0 1 1 1 1 PHD-finger LCCL PF03815.19 XP_666866.1 - 6e-23 80.8 0.4 6e-23 80.8 0.4 2.9 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.25 XP_666866.1 - 9.2e-11 42.0 6.9 0.00011 22.3 0.1 3.4 3 0 0 3 3 3 2 F5/8 type C domain DUF1080 PF06439.11 XP_666866.1 - 2.6e-05 24.4 3.5 0.079 13.1 0.0 2.4 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) HhH-GPD PF00730.25 XP_666867.1 - 5.9e-08 33.1 0.0 6.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 XP_666867.1 - 2.1e-07 30.4 0.0 6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 XP_666867.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain HHH_3 PF12836.7 XP_666867.1 - 0.015 15.5 0.1 0.12 12.6 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 XP_666867.1 - 0.073 13.7 0.0 0.34 11.6 0.0 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix domain Drf_FH1 PF06346.12 XP_666868.1 - 0.58 9.9 8.0 1.3 8.8 8.0 1.5 1 0 0 1 1 1 0 Formin Homology Region 1 Pkinase_Tyr PF07714.17 XP_666870.1 - 0.00017 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 XP_666870.1 - 0.0003 20.2 0.2 0.00045 19.7 0.2 1.3 1 1 0 1 1 1 1 Protein kinase domain SLC3A2_N PF16028.5 XP_666870.1 - 0.045 13.3 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus TPR_1 PF00515.28 XP_666873.1 - 1e-06 28.3 2.6 4.6e-05 23.1 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_666873.1 - 2.3e-05 24.2 0.6 0.0069 16.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 XP_666873.1 - 0.00028 19.7 0.8 0.00038 19.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_17 PF13431.6 XP_666873.1 - 0.025 15.0 2.9 2.5 8.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 XP_666873.1 - 0.031 14.3 3.8 0.88 9.7 1.5 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 XP_666873.1 - 0.052 13.6 4.0 0.28 11.3 0.4 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3552 PF12072.8 XP_666873.1 - 0.17 11.3 5.9 0.28 10.6 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF919 PF06034.11 XP_666873.1 - 0.71 9.8 5.2 1.8 8.5 5.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) WD40 PF00400.32 XP_666874.1 - 7.1e-23 80.5 6.3 6.6e-07 29.9 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_666874.1 - 6.2e-17 61.7 0.4 3.2e-05 24.1 0.0 5.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Invas_SpaK PF03519.14 XP_666874.1 - 0.018 15.1 1.3 13 5.9 0.4 3.5 2 1 1 3 3 3 0 Invasion protein B family DUF3099 PF11298.8 XP_666875.1 - 0.13 12.4 2.0 2.2 8.5 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) PIG-U PF06728.13 XP_666876.1 - 7e-21 74.7 18.3 7.9e-21 74.5 18.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pkinase PF00069.25 XP_666877.1 - 1e-09 38.2 0.7 2.6e-09 36.9 0.7 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666877.1 - 3.6e-06 26.4 0.1 7.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 XP_666877.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAMP_factor PF07373.11 XP_666878.1 - 0.029 14.0 0.6 0.037 13.6 0.6 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) DUF4710 PF15828.5 XP_666878.1 - 0.12 12.5 4.0 0.46 10.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) STAT_alpha PF01017.20 XP_666878.1 - 0.16 11.8 3.6 0.13 12.1 2.4 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain Spore-coat_CotD PF11122.8 XP_666878.1 - 1.1 10.1 7.6 0.41 11.5 4.6 1.8 1 1 1 2 2 2 0 Inner spore coat protein D Peptidase_S9 PF00326.21 XP_666879.1 - 8.5e-30 103.8 0.0 1.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 XP_666879.1 - 1.6e-08 34.7 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 XP_666879.1 - 4.5e-07 29.4 0.0 0.021 14.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_666879.1 - 1.3e-06 28.3 0.4 0.0045 16.7 0.3 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 XP_666879.1 - 7e-06 25.7 0.0 5.2e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 XP_666879.1 - 0.0067 17.1 0.0 0.023 15.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 XP_666879.1 - 0.0075 16.1 0.0 0.28 11.0 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 XP_666879.1 - 0.17 11.7 0.0 1.6 8.5 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold zf-4CXXC_R1 PF10497.9 XP_666880.1 - 0.0054 16.9 9.0 0.0054 16.9 9.0 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Methyltransf_31 PF13847.6 XP_666883.1 - 4.2e-15 55.9 0.1 6e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_666883.1 - 1.4e-08 35.4 0.0 2.5e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_666883.1 - 1.3e-06 29.0 0.0 2.1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666883.1 - 2.4e-06 28.2 0.1 5.5e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_666883.1 - 8.5e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 XP_666883.1 - 1.6e-05 24.9 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 XP_666883.1 - 5.5e-05 22.8 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 XP_666883.1 - 0.00024 20.5 0.0 0.00029 20.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TrmK PF04816.12 XP_666883.1 - 0.0012 18.4 0.1 0.0037 16.8 0.0 1.7 1 1 1 2 2 2 1 tRNA (adenine(22)-N(1))-methyltransferase PrmA PF06325.13 XP_666883.1 - 0.0021 17.5 0.1 0.0028 17.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 XP_666883.1 - 0.0028 17.1 0.0 0.093 12.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 XP_666883.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.8 XP_666883.1 - 0.01 15.0 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 XP_666883.1 - 0.041 12.8 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 XP_666883.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ATP-synt_ab PF00006.25 XP_666885.1 - 8.7e-66 221.6 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 XP_666885.1 - 6.1e-13 49.1 1.6 1.1e-12 48.2 1.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Pkinase PF00069.25 XP_666886.1 - 3.1e-29 102.1 0.0 7.5e-16 58.3 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_666886.1 - 8.7e-08 31.8 0.0 2.5e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_666886.1 - 1e-07 31.6 0.5 2.5e-06 27.0 0.5 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 XP_666886.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 XP_666886.1 - 0.0079 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PBC PF03792.13 XP_666886.1 - 0.081 12.7 1.4 0.16 11.7 1.4 1.4 1 0 0 1 1 1 0 PBC domain APH PF01636.23 XP_666886.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family THP2 PF09432.10 XP_666886.1 - 3.8 7.6 7.1 2.2 8.4 4.1 2.0 1 1 1 2 2 2 0 Tho complex subunit THP2 KH_1 PF00013.29 XP_666887.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 KH domain PRA1 PF03208.19 XP_666888.1 - 4.6e-24 84.7 3.1 6.2e-24 84.3 3.1 1.1 1 0 0 1 1 1 1 PRA1 family protein DHHC PF01529.20 XP_666888.1 - 0.66 10.1 4.3 1.2 9.3 4.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase SLD5_C PF16922.5 XP_666889.1 - 0.00015 21.9 0.0 0.00024 21.2 0.0 1.5 1 1 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus DUF1474 PF07342.11 XP_666889.1 - 0.014 15.9 1.3 0.28 11.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1474) Ig_2 PF13895.6 XP_666889.1 - 0.12 12.7 0.1 8.3 6.8 0.1 2.3 1 1 1 2 2 2 0 Immunoglobulin domain DNA_pol_D_N PF18018.1 XP_666890.1 - 1.3e-33 115.8 0.0 2e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 XP_666890.1 - 2.2e-27 95.8 0.2 3.3e-27 95.2 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MRG PF05712.13 XP_666891.1 - 2.2e-19 69.6 5.3 4.2e-19 68.6 2.9 2.2 2 1 0 2 2 2 1 MRG Hist_deacetyl PF00850.19 XP_666892.1 - 4.5e-63 213.6 0.0 8.4e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 XP_666892.1 - 1.1e-13 51.6 0.1 1.1e-08 35.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_666892.1 - 1.5e-13 51.0 1.0 0.0002 21.9 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_666892.1 - 8.9e-12 44.1 1.1 0.00033 20.9 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 XP_666892.1 - 1.5e-10 41.0 1.9 2e-05 24.8 0.3 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 XP_666892.1 - 7.5e-10 38.9 0.4 3.6e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AhpC-TSA PF00578.21 XP_666892.1 - 0.0094 15.9 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 1 AhpC/TSA family SAS-6_N PF16531.5 XP_666893.1 - 4.1e-17 62.5 0.0 4.3e-16 59.3 0.0 2.9 2 1 0 2 2 1 1 Centriolar protein SAS N-terminal SHE3 PF17078.5 XP_666893.1 - 3.2e-06 27.0 47.0 2.8e-05 23.9 3.5 4.0 1 1 3 4 4 4 2 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 XP_666893.1 - 0.0031 17.7 24.8 0.0031 17.7 24.8 3.7 2 1 2 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus EzrA PF06160.12 XP_666893.1 - 0.0041 15.4 48.5 0.012 13.9 25.0 3.3 1 1 2 3 3 3 2 Septation ring formation regulator, EzrA DUF3450 PF11932.8 XP_666893.1 - 0.11 11.7 35.5 0.013 14.8 13.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Tektin PF03148.14 XP_666893.1 - 0.3 9.8 36.9 0.027 13.2 7.9 3.6 1 1 2 3 3 3 0 Tektin family Flagellin_C PF00700.21 XP_666893.1 - 0.41 11.0 7.8 9 6.7 0.2 4.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region GAS PF13851.6 XP_666893.1 - 0.76 9.1 45.3 0.2 11.0 14.1 3.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 XP_666893.1 - 1.1 9.2 43.4 1.3 9.1 8.1 4.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UspA1_rep PF18792.1 XP_666893.1 - 1.2 9.8 6.0 0.35 11.4 0.5 2.6 2 0 0 2 2 2 0 Ubiquitous surface protein adhesin repeat Spc7 PF08317.11 XP_666893.1 - 1.5 7.6 45.6 0.34 9.8 11.5 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein TACC_C PF05010.14 XP_666893.1 - 1.5 8.5 40.0 4.5 7.0 23.2 3.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 XP_666893.1 - 2.6 8.1 43.3 0.36 10.9 5.9 4.8 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.11 XP_666893.1 - 3.5 6.9 40.5 0.13 11.6 10.7 3.6 1 1 2 3 3 3 0 Rabaptin-like protein MAD PF05557.13 XP_666893.1 - 6.8 4.9 45.8 2 6.7 28.6 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein PI3K_P85_iSH2 PF16454.5 XP_666893.1 - 9.2 5.8 36.2 0.071 12.7 14.5 4.2 1 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_DNA_bd PF12329.8 XP_666893.1 - 9.2 6.3 49.8 0.77 9.8 1.7 6.5 3 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 XP_666893.1 - 9.5 6.3 27.2 3.3 7.8 5.7 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) EF-hand_8 PF13833.6 XP_666894.1 - 4e-13 49.0 1.7 5.6e-08 32.5 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_666894.1 - 1.9e-08 33.3 1.0 0.012 15.1 0.0 3.7 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 XP_666894.1 - 1.1e-07 31.2 1.4 0.07 13.1 0.1 4.0 4 1 1 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 XP_666894.1 - 1.7e-07 31.5 1.2 0.0084 16.5 0.0 3.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 XP_666894.1 - 0.01 15.3 5.9 1.4 8.6 0.4 3.9 3 1 1 4 4 4 0 EF hand EF-hand_9 PF14658.6 XP_666894.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF5475 PF17569.2 XP_666894.1 - 0.12 12.7 0.0 0.41 11.0 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5475) SpoVAD PF07451.11 XP_666895.1 - 0.12 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) PseudoU_synth_1 PF01416.20 XP_666896.1 - 8.8e-15 55.1 0.0 1.3e-12 48.2 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Img2 PF05046.14 XP_666896.1 - 0.15 12.4 1.0 0.57 10.5 0.1 2.4 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) DivIC PF04977.15 XP_666897.1 - 0.11 12.3 0.4 0.11 12.3 0.4 5.0 3 2 2 5 5 5 0 Septum formation initiator Transglut_core2 PF13369.6 XP_666897.1 - 0.2 11.2 0.2 13 5.3 0.1 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF2785 PF10978.8 XP_666897.1 - 1.8 8.3 7.0 2 8.2 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) TPP_enzyme_C PF02775.21 XP_666897.1 - 4.4 7.1 6.8 0.28 11.0 0.5 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sec63 PF02889.16 XP_666898.1 - 8.9e-66 221.7 6.0 1.7e-38 132.3 3.4 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 XP_666898.1 - 7e-49 166.0 0.0 4.2e-24 85.2 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 XP_666898.1 - 2e-19 70.2 7.5 6.4e-11 42.5 0.0 3.6 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 XP_666898.1 - 2.7e-14 53.5 3.3 6.4e-05 23.3 0.0 4.9 2 2 2 4 4 4 2 Helicase conserved C-terminal domain PhoH PF02562.16 XP_666898.1 - 0.0014 18.1 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 XP_666898.1 - 0.0054 15.8 0.0 0.81 8.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 XP_666898.1 - 0.024 14.9 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 XP_666898.1 - 0.041 14.2 0.8 19 5.5 0.0 4.2 4 1 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 XP_666898.1 - 0.087 12.2 0.0 4.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI dCMP_cyt_deam_1 PF00383.23 XP_666899.1 - 1.4e-27 95.5 3.5 2.2e-27 94.9 3.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 XP_666899.1 - 4.4e-18 65.3 0.9 7.5e-18 64.6 0.9 1.4 1 0 0 1 1 1 1 MafB19-like deaminase YpsA PF06908.11 XP_666899.1 - 0.038 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family SNAD4 PF18750.1 XP_666899.1 - 0.38 10.9 2.2 0.9 9.7 2.2 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DFRP_C PF16543.5 XP_666900.1 - 3.2e-20 72.4 1.2 3.2e-20 72.4 1.2 3.6 2 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Ndc1_Nup PF09531.10 XP_666900.1 - 4.4 5.9 8.1 6.8 5.2 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ACR_tran PF00873.19 XP_666900.1 - 5 4.6 10.4 0.2 9.3 0.1 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family THUMP PF02926.17 XP_666901.1 - 5.1e-05 23.4 0.0 0.00013 22.1 0.0 1.9 1 1 0 1 1 1 1 THUMP domain SYF2 PF08231.12 XP_666902.1 - 3.2e-11 43.9 16.2 3.2e-11 43.9 16.2 2.2 1 1 1 2 2 2 1 SYF2 splicing factor DUF3768 PF12599.8 XP_666902.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) Methyltransf_23 PF13489.6 XP_666903.1 - 9.2e-13 48.3 0.0 3.3e-12 46.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_666903.1 - 4.9e-09 36.7 0.0 6.3e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666903.1 - 1e-08 35.1 0.0 7.2e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_666903.1 - 4.6e-07 30.5 0.1 4.2e-05 24.2 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666903.1 - 9.7e-07 29.5 0.1 4.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 XP_666903.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 XP_666903.1 - 0.00028 20.4 0.0 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 XP_666903.1 - 0.051 12.5 0.0 0.24 10.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) NodS PF05401.11 XP_666903.1 - 0.053 13.1 0.1 8.7 5.9 0.1 2.4 1 1 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.20 XP_666903.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 XP_666903.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PH PF00169.29 XP_666904.1 - 3.2e-07 30.8 0.6 3.2e-07 30.8 0.6 2.2 2 0 0 2 2 2 1 PH domain Ank_5 PF13857.6 XP_666904.1 - 0.0006 20.1 0.0 0.0028 17.9 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 XP_666904.1 - 0.0025 18.3 0.3 0.1 13.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_666904.1 - 0.006 17.1 0.2 0.54 10.9 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 XP_666904.1 - 0.024 15.1 0.1 8 7.1 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat PH_11 PF15413.6 XP_666904.1 - 0.064 13.7 0.6 0.53 10.7 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain HTH_16 PF12645.7 XP_666904.1 - 0.47 10.5 1.8 45 4.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain bZIP_2 PF07716.15 XP_666905.1 - 0.00031 20.7 10.1 0.00031 20.7 10.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 XP_666905.1 - 0.0036 17.4 8.1 0.014 15.5 8.1 2.0 1 0 0 1 1 1 1 bZIP transcription factor LRR_4 PF12799.7 XP_666906.1 - 1.1e-29 102.0 59.8 1.4e-08 34.8 6.0 7.1 2 2 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 XP_666906.1 - 7.7e-22 77.6 30.7 2.1e-07 30.6 1.7 4.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.6 XP_666906.1 - 2.6e-20 71.9 45.7 4.2e-09 36.0 2.3 6.8 3 2 3 7 7 7 7 Leucine rich repeat Latarcin PF10279.9 XP_666906.1 - 0.0033 17.8 0.0 5.8 7.4 0.5 3.0 1 1 1 2 2 2 2 Latarcin precursor LRR_1 PF00560.33 XP_666906.1 - 0.0068 16.8 39.9 3.2 8.7 0.0 10.0 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_2 PF07723.13 XP_666906.1 - 0.2 12.4 6.2 12 6.8 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 XP_666906.1 - 0.27 11.4 35.9 1 9.6 0.2 9.7 11 0 0 11 11 11 0 Leucine Rich repeat IGR PF09597.10 XP_666906.1 - 0.36 11.0 2.6 7.4 6.8 0.1 3.7 2 1 2 4 4 4 0 IGR protein motif Pallilysin PF18663.1 XP_666906.1 - 8 6.5 10.6 6.3 6.8 0.6 3.3 2 2 1 3 3 3 0 Pallilysin beta barrel domain Rhomboid PF01694.22 XP_666907.1 - 8.3e-27 94.0 15.2 8.3e-27 94.0 15.2 1.9 3 0 0 3 3 3 1 Rhomboid family Sdh_cyt PF01127.22 XP_666907.1 - 0.62 10.1 6.4 8.9 6.4 1.3 2.8 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ANAPC_CDC26 PF10471.9 XP_666908.1 - 3.5e-06 27.7 2.8 4.9e-06 27.3 2.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 TSP_1 PF00090.19 XP_666910.1 - 4.1e-10 39.7 27.2 1.1e-06 28.7 5.5 3.5 3 1 0 3 3 3 2 Thrombospondin type 1 domain EGF PF00008.27 XP_666910.1 - 9.6e-07 29.0 8.6 9.6e-07 29.0 8.6 3.5 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 XP_666910.1 - 0.029 15.0 7.5 0.029 15.0 7.5 3.2 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.13 XP_666910.1 - 0.057 13.8 14.0 0.057 13.8 14.0 3.7 2 2 1 3 3 3 0 EGF-like domain GHMP_kinases_C PF08544.13 XP_666911.1 - 0.21 12.0 0.0 16 5.9 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal EGF PF00008.27 XP_666912.1 - 1.6e-08 34.7 7.0 4.5e-08 33.2 7.0 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 XP_666912.1 - 4.9e-05 23.8 4.4 0.00017 22.1 4.4 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 XP_666912.1 - 0.0059 16.9 12.8 0.013 15.9 12.8 1.6 1 0 0 1 1 1 1 EGF-like domain CRT-like PF08627.10 XP_666912.1 - 0.0067 15.4 0.3 0.0076 15.2 0.3 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RTT107_BRCT_5 PF16770.5 XP_666913.1 - 7.6e-08 32.2 0.1 1.8e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 XP_666913.1 - 0.00032 21.0 1.9 0.13 12.7 0.1 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 XP_666913.1 - 0.00046 20.5 0.2 0.002 18.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain DUF1075 PF06388.11 XP_666913.1 - 0.087 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Metallophos PF00149.28 XP_666914.1 - 3.7e-32 112.5 1.0 6.8e-32 111.6 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 XP_666914.1 - 1.9e-15 56.9 0.0 8e-15 54.9 0.1 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 XP_666914.1 - 2.3e-13 49.4 5.3 0.00022 20.9 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 XP_666914.1 - 2.8e-11 42.6 0.7 0.014 15.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 XP_666914.1 - 7e-06 25.8 3.3 0.072 13.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 XP_666914.1 - 1.5e-05 24.6 0.2 0.089 12.5 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 XP_666914.1 - 4.4e-05 23.7 0.5 0.0018 18.5 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 XP_666914.1 - 0.0051 17.1 0.1 0.098 13.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 XP_666914.1 - 0.011 15.1 0.5 0.018 14.4 0.5 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP SusD-like_3 PF14322.6 XP_666914.1 - 0.023 15.0 1.6 0.05 13.9 1.6 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane TPR_6 PF13174.6 XP_666914.1 - 0.098 13.3 0.8 4.3 8.2 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_666914.1 - 0.1 12.9 1.9 0.29 11.4 1.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 XP_666914.1 - 0.11 12.2 2.6 0.15 11.8 2.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.6 XP_666914.1 - 0.19 11.8 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 XP_666914.1 - 0.34 11.0 2.1 1.1 9.4 0.3 2.6 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ribosomal_L13e PF01294.18 XP_666916.1 - 5.1e-63 212.2 1.4 6.1e-63 211.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 XP_666917.1 - 6.4e-29 100.9 0.1 7.4e-29 100.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF630 PF04783.12 XP_666917.1 - 0.059 13.6 0.1 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) AAA PF00004.29 XP_666918.1 - 2.9e-52 176.6 0.0 2.7e-39 134.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 XP_666918.1 - 3.1e-10 40.7 0.3 0.00057 20.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 XP_666918.1 - 1.4e-09 38.3 2.6 0.0013 19.1 0.2 4.8 3 2 1 4 4 3 1 AAA domain AAA_lid_3 PF17862.1 XP_666918.1 - 4.1e-09 36.1 0.0 9.3e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 XP_666918.1 - 7.7e-09 35.7 0.0 0.00037 20.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 XP_666918.1 - 4.3e-07 29.5 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 XP_666918.1 - 8.1e-07 29.4 0.0 0.069 13.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 XP_666918.1 - 1.1e-06 28.7 0.2 0.044 13.8 0.0 2.9 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 XP_666918.1 - 9.5e-06 25.8 0.0 7.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 XP_666918.1 - 1.9e-05 24.4 0.1 0.099 12.3 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 XP_666918.1 - 2.1e-05 24.7 0.0 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 XP_666918.1 - 2.8e-05 24.1 3.4 0.14 12.1 0.0 3.7 4 1 0 5 5 4 2 NACHT domain Mg_chelatase PF01078.21 XP_666918.1 - 4.2e-05 23.0 0.1 0.0044 16.4 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 XP_666918.1 - 5.4e-05 22.8 0.7 0.12 11.9 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 XP_666918.1 - 5.8e-05 22.9 0.0 0.14 11.9 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 XP_666918.1 - 7e-05 22.9 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 XP_666918.1 - 7.3e-05 22.2 0.0 0.17 11.2 0.0 2.5 2 0 0 2 2 2 2 KaiC RuvB_N PF05496.12 XP_666918.1 - 8.3e-05 22.4 0.0 0.038 13.7 0.0 2.9 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 XP_666918.1 - 0.00016 22.2 0.6 0.028 14.9 0.1 2.9 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 XP_666918.1 - 0.00017 20.9 0.0 0.19 10.9 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DAP3 PF10236.9 XP_666918.1 - 0.00022 20.5 0.1 0.12 11.5 0.1 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 XP_666918.1 - 0.00027 20.6 0.1 0.43 10.1 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 XP_666918.1 - 0.00032 21.3 0.0 0.19 12.3 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 XP_666918.1 - 0.00066 19.5 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 XP_666918.1 - 0.0017 18.1 0.0 0.035 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 XP_666918.1 - 0.002 17.5 0.2 2.4 7.5 0.0 3.0 2 1 1 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 XP_666918.1 - 0.0026 17.3 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 XP_666918.1 - 0.0048 17.1 0.0 0.34 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 XP_666918.1 - 0.0056 16.0 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 XP_666918.1 - 0.0088 16.2 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Torsin AAA_3 PF07726.11 XP_666918.1 - 0.01 15.7 0.0 0.061 13.2 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 XP_666918.1 - 0.012 16.0 0.1 0.18 12.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 XP_666918.1 - 0.012 15.6 0.1 0.2 11.6 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 XP_666918.1 - 0.015 15.2 0.0 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 XP_666918.1 - 0.02 14.0 0.1 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 XP_666918.1 - 0.02 14.7 0.0 0.055 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 XP_666918.1 - 0.022 14.6 0.7 12 5.7 0.0 3.3 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 XP_666918.1 - 0.033 14.3 0.0 8.1 6.6 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 XP_666918.1 - 0.053 12.7 0.1 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 XP_666918.1 - 0.056 13.2 0.2 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.6 XP_666918.1 - 0.11 12.3 0.1 7.1 6.4 0.0 3.1 3 1 0 4 4 3 0 DNA polymerase III, delta subunit KTI12 PF08433.10 XP_666918.1 - 0.13 11.7 0.2 0.79 9.1 0.0 2.4 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 XP_666918.1 - 0.19 11.0 0.1 15 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Vps36_ESCRT-II PF11605.8 XP_666919.1 - 0.012 15.8 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 TssO PF17561.2 XP_666920.1 - 0.039 14.1 5.8 0.054 13.6 5.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO ATG16 PF08614.11 XP_666921.1 - 2.2e-05 24.8 49.0 0.0012 19.1 18.9 3.4 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 XP_666921.1 - 0.0011 19.0 35.3 0.13 12.3 1.3 4.8 4 1 1 5 5 5 3 Protein of unknown function (DUF1664) SlyX PF04102.12 XP_666921.1 - 0.0066 17.0 7.5 0.0066 17.0 7.5 7.6 5 2 2 8 8 8 2 SlyX SHE3 PF17078.5 XP_666921.1 - 0.0084 15.8 18.0 0.0084 15.8 18.0 3.7 4 0 0 4 4 4 1 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 XP_666921.1 - 0.055 13.8 0.7 0.055 13.8 0.7 5.6 5 1 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 XP_666921.1 - 0.16 11.3 59.3 3.9 6.8 5.6 4.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.11 XP_666921.1 - 0.42 10.4 35.3 0.064 13.1 8.2 4.3 3 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HOOK PF05622.12 XP_666921.1 - 0.76 7.8 60.5 0.12 10.5 13.8 4.5 2 1 2 4 4 4 0 HOOK protein DUF4201 PF13870.6 XP_666921.1 - 4.8 6.9 56.8 0.34 10.6 10.3 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4201) DAGK_acc PF00609.19 XP_666922.1 - 6.8e-32 111.0 0.3 1.5e-16 61.2 0.0 2.2 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain Citrus_P18 PF05520.11 XP_666922.1 - 0.057 13.1 0.4 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein zf-RING_2 PF13639.6 XP_666924.1 - 5e-08 33.2 9.3 2.4e-07 31.0 9.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 XP_666924.1 - 7.5e-08 32.3 2.0 1.3e-07 31.5 1.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 XP_666924.1 - 5.6e-07 29.1 2.1 5.6e-07 29.1 2.1 1.8 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 XP_666924.1 - 4.3e-06 26.4 3.0 1e-05 25.1 3.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 XP_666924.1 - 7.8e-06 25.7 5.7 4.9e-05 23.1 5.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_666924.1 - 9.4e-06 25.4 3.4 9.4e-06 25.4 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 XP_666924.1 - 1.6e-05 25.1 8.3 0.00017 21.8 8.3 2.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 XP_666924.1 - 0.00013 21.8 4.1 0.00036 20.4 4.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 XP_666924.1 - 0.0013 18.8 1.7 0.0013 18.8 1.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 XP_666924.1 - 0.0071 16.4 1.3 0.0071 16.4 1.3 2.3 2 0 0 2 2 2 1 KIAA1045 RING finger zf-ANAPC11 PF12861.7 XP_666924.1 - 0.021 14.9 1.6 0.021 14.9 1.6 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 XP_666924.1 - 0.1 12.7 3.5 0.28 11.3 3.5 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 XP_666924.1 - 0.14 12.1 6.8 1.2 9.0 2.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 XP_666924.1 - 0.27 11.7 4.5 0.3 11.6 1.2 3.0 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.8 XP_666924.1 - 2.1 8.6 8.4 12 6.1 8.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 XP_666924.1 - 3.2 7.7 10.4 1.2 9.0 3.4 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF2587 PF10759.9 XP_666926.1 - 0.079 12.5 0.1 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2587) BSD PF03909.17 XP_666928.1 - 0.073 13.1 0.2 0.077 13.0 0.2 1.1 1 0 0 1 1 1 0 BSD domain Sin3_corepress PF08295.12 XP_666929.1 - 1.3e-35 121.4 0.2 1.3e-35 121.4 0.2 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Sin3a_C PF16879.5 XP_666929.1 - 4.1e-20 72.7 0.3 4.1e-20 72.7 0.3 2.7 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Band_7 PF01145.25 XP_666930.1 - 2.8e-23 82.9 0.6 3.6e-23 82.5 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 XP_666930.1 - 0.072 13.3 1.6 0.14 12.3 1.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Actin PF00022.19 XP_666931.1 - 2e-120 402.1 0.0 2.6e-119 398.5 0.0 1.9 1 1 0 1 1 1 1 Actin SET PF00856.28 XP_666932.1 - 0.00027 21.4 0.1 0.036 14.4 0.0 2.9 2 1 1 3 3 3 2 SET domain UPF0203 PF05254.12 XP_666933.1 - 6.2e-10 39.2 5.1 6.4e-10 39.1 4.3 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 XP_666933.1 - 5.8e-05 23.1 1.6 0.00012 22.1 1.6 1.6 1 1 0 1 1 1 1 CHCH domain UCH PF00443.29 XP_666934.1 - 9.5e-12 44.9 8.7 2e-11 43.9 8.7 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 XP_666934.1 - 1.3e-08 35.0 3.0 2.8e-08 34.0 3.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF4187 PF13821.6 XP_666934.1 - 0.076 12.8 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Nas2_N PF18265.1 XP_666935.1 - 4.3e-30 103.5 0.0 8e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 XP_666935.1 - 2.8e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 XP_666935.1 - 0.00052 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF1048 PF06304.11 XP_666935.1 - 0.024 15.1 0.1 0.055 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) PDZ PF00595.24 XP_666935.1 - 0.031 14.6 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.14 XP_666935.1 - 0.075 13.4 0.0 0.8 10.0 0.0 2.2 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Ribosomal_60s PF00428.19 XP_666936.1 - 7e-22 77.8 5.1 1.1e-21 77.2 5.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Macoilin PF09726.9 XP_666937.1 - 0.032 12.8 19.9 0.053 12.1 19.9 1.3 1 1 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 XP_666937.1 - 8.3 5.0 8.8 11 4.6 8.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CS PF04969.16 XP_666939.1 - 4.1e-10 40.5 0.3 6.3e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 CS domain Rtt102p PF09510.10 XP_666939.1 - 0.53 10.5 6.4 0.87 9.8 6.4 1.3 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein DOT1 PF08123.13 XP_666941.1 - 7.3e-05 22.4 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 GidB PF02527.15 XP_666941.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MFAP1 PF06991.11 XP_666942.1 - 1.3e-08 34.9 2.5 1.6e-08 34.7 2.5 1.1 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing MIF4G PF02854.19 XP_666943.1 - 2.4e-29 102.5 8.4 2.4e-29 102.5 8.4 2.1 2 0 0 2 2 2 1 MIF4G domain PAM2 PF07145.15 XP_666943.1 - 2.8e-08 32.9 0.0 4.8e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 Ataxin-2 C-terminal region MA3 PF02847.17 XP_666943.1 - 0.086 12.8 1.3 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 MA3 domain XPG_I PF00867.18 XP_666944.1 - 1.1e-20 73.7 0.8 4.4e-20 71.8 0.1 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 XP_666944.1 - 3.2e-18 66.0 0.0 1.4e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 XP_666944.1 - 5e-05 22.9 0.0 9.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing Apyrase PF06079.11 XP_666945.1 - 7.7e-112 373.3 1.3 8.8e-112 373.1 1.3 1.0 1 0 0 1 1 1 1 Apyrase Reg_prop PF07494.11 XP_666945.1 - 0.0054 16.8 1.1 7.9 7.1 0.1 3.5 3 0 0 3 3 3 2 Two component regulator propeller RsgI_N PF12791.7 XP_666945.1 - 0.1 12.5 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Anti-sigma factor N-terminus PCNA_N PF00705.18 XP_666947.1 - 3e-38 130.4 4.5 4.6e-38 129.8 4.5 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 XP_666947.1 - 2.4e-32 111.8 0.0 8.8e-29 100.3 0.0 2.2 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 XP_666947.1 - 1.7e-09 37.2 0.8 1.3e-07 31.0 0.3 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 XP_666947.1 - 1.9e-06 27.5 0.2 3.8e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 Rad9 DNA_pol3_beta_2 PF02767.16 XP_666947.1 - 0.013 15.7 0.0 0.32 11.2 0.0 2.3 2 1 0 2 2 2 0 DNA polymerase III beta subunit, central domain Hus1 PF04005.12 XP_666947.1 - 0.13 11.4 0.5 0.61 9.1 0.3 2.2 2 1 0 2 2 2 0 Hus1-like protein DWNN PF08783.11 XP_666948.1 - 2.8e-12 46.7 0.1 2.8e-12 46.7 0.1 2.7 3 0 0 3 3 3 1 DWNN domain zf-RING_2 PF13639.6 XP_666948.1 - 0.038 14.3 6.0 0.079 13.3 6.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 XP_666948.1 - 0.38 10.7 6.0 0.61 10.0 6.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 XP_666948.1 - 0.61 10.3 9.3 0.53 10.5 6.8 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 XP_666948.1 - 0.65 9.8 3.8 1.4 8.8 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 XP_666948.1 - 0.92 9.4 8.0 2.2 8.2 8.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_666948.1 - 1.3 9.0 7.5 2.4 8.1 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_666948.1 - 5.8 7.0 6.7 12 6.0 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HSP70 PF00012.20 XP_666950.1 - 6.9e-261 866.7 9.4 7.8e-261 866.5 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 XP_666950.1 - 3.7e-15 55.6 1.6 1.2e-13 50.6 0.4 2.6 2 1 0 2 2 2 1 MreB/Mbl protein GLE1 PF07817.13 XP_666950.1 - 0.00065 19.0 2.7 0.74 9.0 3.4 2.3 2 0 0 2 2 2 2 GLE1-like protein FGGY_C PF02782.16 XP_666950.1 - 0.0077 16.0 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 XP_666950.1 - 0.029 14.8 0.8 12 6.4 0.0 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Syntaxin-6_N PF09177.11 XP_666950.1 - 0.53 10.9 5.2 6.4 7.4 5.2 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Cu_amine_oxid PF01179.20 XP_666951.1 - 1.7e-66 224.9 0.1 2.5e-66 224.3 0.1 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.23 XP_666951.1 - 6.2e-13 49.0 0.0 1.9e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu EF-hand_7 PF13499.6 XP_666952.1 - 2.2e-10 40.8 2.4 5.5e-10 39.6 2.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 XP_666952.1 - 1.1e-09 37.2 6.3 7.3e-05 22.0 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 XP_666952.1 - 4.7e-09 35.5 5.1 0.0001 22.0 0.4 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 XP_666952.1 - 9.4e-08 31.8 5.5 0.002 18.0 1.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair COPI_assoc PF08507.10 XP_666952.1 - 0.00013 22.1 14.5 0.0002 21.4 14.5 1.3 1 0 0 1 1 1 1 COPI associated protein EF-hand_5 PF13202.6 XP_666952.1 - 0.00029 20.2 7.6 0.034 13.6 0.4 3.5 3 0 0 3 3 3 2 EF hand Tox-GHH PF15636.6 XP_666952.1 - 0.52 10.3 3.1 6.6 6.8 0.3 3.0 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Cg6151-P PF10233.9 XP_666952.1 - 2 8.7 10.4 3.3 8.1 10.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Phage_int_SAM_1 PF02899.17 XP_666953.1 - 0.054 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ABC_tran PF00005.27 XP_666954.1 - 5.5e-46 156.5 0.0 5.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 XP_666954.1 - 2.2e-34 119.4 30.2 8.7e-28 97.7 11.0 3.5 3 1 0 3 3 3 3 ABC transporter transmembrane region AAA_29 PF13555.6 XP_666954.1 - 8.5e-07 28.6 0.2 0.039 13.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 XP_666954.1 - 3.1e-05 23.5 13.0 0.047 13.1 0.9 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 XP_666954.1 - 0.00015 22.0 0.1 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 XP_666954.1 - 0.00015 21.8 0.2 0.0076 16.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 XP_666954.1 - 0.00063 19.7 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_21 PF13304.6 XP_666954.1 - 0.00077 19.4 3.5 0.073 12.9 0.2 3.6 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 XP_666954.1 - 0.005 16.8 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 XP_666954.1 - 0.0096 16.2 0.0 4.1 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 XP_666954.1 - 0.0096 15.1 1.4 1.8 7.7 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain cobW PF02492.19 XP_666954.1 - 0.014 15.0 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 XP_666954.1 - 0.13 12.6 0.0 26 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 XP_666954.1 - 0.19 12.2 7.0 0.35 11.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain TMEMspv1-c74-12 PF11044.8 XP_666955.1 - 0.0021 18.0 0.7 0.0062 16.5 0.7 1.8 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein ISP3_C PF18045.1 XP_666956.1 - 3e-25 88.2 0.6 3.9e-25 87.9 0.6 1.1 1 0 0 1 1 1 1 ISP3 C-terminal ISP1_C PF18161.1 XP_666956.1 - 2.1e-22 79.2 0.7 2.7e-22 78.8 0.7 1.1 1 0 0 1 1 1 1 ISP1 C-terminal APP_N PF02177.16 XP_666957.1 - 0.032 14.6 0.4 0.071 13.5 0.0 1.7 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding 2OG-FeII_Oxy_2 PF13532.6 XP_666959.1 - 1.3e-17 64.6 0.1 1.5e-16 61.2 0.1 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3638 PF12340.8 XP_666960.1 - 4.7e-23 81.7 0.2 1.8e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 XP_666960.1 - 2.8e-14 52.2 0.1 5.1e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_6 PF13405.6 XP_666960.1 - 9.8e-07 28.2 0.3 0.031 14.2 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 XP_666960.1 - 2.2e-05 23.7 3.1 0.016 14.7 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 XP_666960.1 - 0.0019 18.6 0.6 0.67 10.5 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair ResIII PF04851.15 XP_666960.1 - 0.13 12.3 0.0 0.13 12.3 0.0 4.0 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Serglycin PF04360.12 XP_666960.1 - 1.6 8.6 13.5 3.8 7.5 1.1 4.7 4 0 0 4 4 4 0 Serglycin Hexapep PF00132.24 XP_666961.1 - 8.7e-06 25.3 21.5 0.022 14.5 7.3 4.1 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 XP_666961.1 - 0.00085 19.0 10.8 1.4 8.8 0.1 3.4 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 XP_666961.1 - 0.016 14.2 8.2 0.058 12.3 3.6 2.1 1 1 1 2 2 2 0 L-fucokinase CTP_transf_like PF01467.26 XP_666963.1 - 1e-30 106.8 0.0 9.2e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 XP_666963.1 - 0.0011 18.9 0.3 2.1 8.2 0.1 2.9 3 0 0 3 3 3 2 FAD synthetase DUF726 PF05277.12 XP_666963.1 - 0.012 14.5 0.0 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF726) Clat_adaptor_s PF01217.20 XP_666964.1 - 0.004 17.1 2.5 0.0071 16.3 2.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MCM PF00493.23 XP_666966.1 - 2.1e-98 327.9 0.2 4e-98 327.0 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 XP_666966.1 - 9.6e-31 106.3 0.1 1.7e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 XP_666966.1 - 3.4e-26 91.5 1.1 7.7e-26 90.3 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 XP_666966.1 - 6.7e-08 33.1 0.1 0.00031 21.3 0.1 2.7 2 0 0 2 2 2 2 MCM N-terminal domain Mg_chelatase PF01078.21 XP_666966.1 - 2e-06 27.4 0.0 3.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 XP_666966.1 - 0.0095 15.9 0.0 0.03 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 XP_666966.1 - 0.069 12.9 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 XP_666966.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_MCEL PF03291.16 XP_666967.1 - 2.9e-41 141.7 8.8 2.7e-40 138.5 8.7 2.2 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 XP_666967.1 - 7e-13 49.1 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_666967.1 - 3.6e-11 43.1 0.1 7.4e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_666967.1 - 5.5e-10 39.9 0.0 1.4e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_666967.1 - 2.6e-09 37.1 0.0 5.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_666967.1 - 7e-09 36.2 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain mRNA_triPase PF02940.15 XP_666967.1 - 2.2e-05 24.3 0.4 5.8e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CMAS PF02353.20 XP_666967.1 - 0.0068 15.7 0.2 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 XP_666967.1 - 0.019 15.0 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_5 PF01795.19 XP_666967.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_20 PF12147.8 XP_666967.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Topoisom_I_N PF02919.15 XP_666967.1 - 0.11 12.0 0.6 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment JAB PF01398.21 XP_666968.1 - 4.4e-30 104.1 0.0 6.9e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 XP_666968.1 - 2.8e-27 95.4 0.1 4.4e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function TFIID_20kDa PF03847.13 XP_666970.1 - 2.7e-05 24.6 0.0 6.9e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 XP_666970.1 - 0.00041 20.7 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF643 PF04867.12 XP_666970.1 - 0.0062 17.1 0.1 0.012 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF643) TFIID-31kDa PF02291.15 XP_666970.1 - 0.02 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 XP_666970.1 - 0.047 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAFII55_N PF04658.13 XP_666972.1 - 1.2e-13 51.1 0.0 3.9e-13 49.4 0.0 1.9 2 1 0 2 2 2 1 TAFII55 protein conserved region DLIC PF05783.11 XP_666973.1 - 0.00019 20.4 17.8 0.0063 15.4 0.0 4.4 3 2 0 4 4 4 3 Dynein light intermediate chain (DLIC) PITH PF06201.13 XP_666976.1 - 6.6e-32 110.8 0.0 8.4e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain SNF2_N PF00176.23 XP_666977.1 - 3.5e-61 206.9 0.4 2.6e-60 204.0 0.1 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 XP_666977.1 - 1.5e-23 82.4 2.4 1.5e-10 40.8 0.5 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 XP_666977.1 - 2.9e-20 72.7 0.0 1e-19 70.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 XP_666977.1 - 2.3e-10 40.1 1.0 2.3e-10 40.1 1.0 3.2 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 XP_666977.1 - 1.9e-08 34.5 1.9 2.1e-07 31.1 0.0 3.8 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit DUF4208 PF13907.6 XP_666977.1 - 2.5e-06 27.8 0.1 2.5e-05 24.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) DEAD PF00270.29 XP_666977.1 - 0.00049 19.9 0.0 0.022 14.5 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase CDH1_2_SANT_HL1 PF18375.1 XP_666977.1 - 0.064 13.9 0.3 0.064 13.9 0.3 4.4 4 1 1 5 5 5 0 CDH1/2 SANT-Helical linker 1 Plasmod_Pvs28 PF06247.11 XP_666978.1 - 1.6e-05 25.1 3.3 3.4e-05 24.1 3.3 1.6 1 1 0 1 1 1 1 Pvs28 EGF domain EGF_2 PF07974.13 XP_666978.1 - 0.00057 20.2 9.3 0.00095 19.5 9.3 1.4 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 XP_666978.1 - 0.00067 19.9 5.2 0.0013 19.0 5.2 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.7 XP_666978.1 - 0.015 15.5 7.5 0.025 14.8 7.5 1.5 1 0 0 1 1 1 0 EGF domain hEGF PF12661.7 XP_666978.1 - 0.05 14.3 2.3 0.085 13.5 0.8 2.2 1 1 1 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 XP_666978.1 - 0.081 13.1 4.2 0.15 12.2 4.2 1.5 1 1 0 1 1 1 0 Laminin EGF domain EGF_CA PF07645.15 XP_666978.1 - 0.23 11.7 5.9 0.48 10.7 5.9 1.5 1 1 0 1 1 1 0 Calcium-binding EGF domain DUF5388 PF17363.2 XP_666979.1 - 0.032 14.4 0.9 0.049 13.8 0.7 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5388) YbbR PF07949.12 XP_666980.1 - 0.0026 18.1 0.0 0.0085 16.4 0.0 1.9 2 0 0 2 2 2 1 YbbR-like protein ATG7_N PF16420.5 XP_666983.1 - 1.4e-05 24.9 0.1 1.5e-05 24.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 XP_666984.1 - 3.8e-34 118.1 0.0 6.6e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Ephrin_rec_like PF07699.13 XP_666986.1 - 0.29 10.9 33.1 0.03 14.1 6.1 4.2 2 2 1 4 4 4 0 Putative ephrin-receptor like Laminin_EGF PF00053.24 XP_666986.1 - 3.9 7.7 27.5 0.08 13.1 10.3 3.2 3 0 0 3 3 3 0 Laminin EGF domain PUA PF01472.20 XP_666987.1 - 0.0012 18.8 0.0 0.0045 16.9 0.0 2.0 1 1 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 XP_666987.1 - 0.73 10.6 5.2 8.7 7.1 0.4 3.6 2 1 1 3 3 3 0 Pre-PUA-like domain Syja_N PF02383.18 XP_666988.1 - 9.9e-74 248.5 1.6 1.7e-73 247.7 1.6 1.4 1 0 0 1 1 1 1 SacI homology domain DUF4804 PF16062.5 XP_666988.1 - 0.039 12.8 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4804) Proteasom_PSMB PF10508.9 XP_666989.1 - 0.036 12.6 0.7 0.16 10.4 0.1 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Polbeta PF18765.1 XP_666990.1 - 0.00092 19.3 0.0 0.0034 17.4 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 XP_666990.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Nrap_D2 PF17403.2 XP_666990.1 - 0.088 12.6 1.0 0.6 9.9 0.0 2.7 3 0 0 3 3 3 0 Nrap protein PAP/OAS-like domain Big_7 PF17957.1 XP_666990.1 - 3.2 8.6 7.6 0.78 10.5 3.6 2.1 2 0 0 2 2 2 0 Bacterial Ig domain SMC_N PF02463.19 XP_666991.1 - 1.7e-51 174.8 40.2 1.3e-50 171.9 40.2 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 XP_666991.1 - 7e-19 69.1 7.3 7e-19 69.1 7.3 7.8 3 2 3 6 6 6 1 AAA domain SMC_hinge PF06470.13 XP_666991.1 - 5.2e-16 59.0 0.0 3.3e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 XP_666991.1 - 1.3e-14 54.8 8.3 8.6e-09 35.6 1.9 5.1 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 XP_666991.1 - 4.8e-07 29.4 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 XP_666991.1 - 0.00016 21.8 0.0 0.00084 19.5 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 XP_666991.1 - 0.059 13.9 0.0 0.059 13.9 0.0 6.6 5 3 1 6 6 6 0 ABC transporter DUF3924 PF13062.6 XP_666991.1 - 0.064 13.2 3.3 0.048 13.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) AAA_22 PF13401.6 XP_666991.1 - 0.39 11.0 9.3 3.3 8.0 0.0 4.9 4 1 1 5 5 5 0 AAA domain AAA PF00004.29 XP_666991.1 - 6.4 7.2 9.7 30 5.0 0.0 4.2 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) Peptidase_M16_C PF05193.21 XP_666992.1 - 6.8e-12 45.8 0.1 2.6e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_666992.1 - 0.0062 16.5 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Vps55 PF04133.14 XP_666993.1 - 0.12 12.4 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Cyclin_N PF00134.23 XP_666994.1 - 5.2e-27 94.1 1.2 7.6e-27 93.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 XP_666994.1 - 0.0013 18.8 0.1 0.0028 17.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain AAA_18 PF13238.6 XP_666994.1 - 0.082 13.5 0.3 0.22 12.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L21e PF01157.18 XP_666995.1 - 0.13 12.1 0.5 0.2 11.5 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L21e Bax1-I PF01027.20 XP_666996.1 - 3e-25 89.3 40.7 3.6e-25 89.0 40.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CSN8_PSD8_EIF3K PF10075.9 XP_666997.1 - 3.4e-32 111.4 0.0 6.2e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF3865 PF12981.7 XP_666997.1 - 0.046 13.6 0.4 0.082 12.8 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) SAC3_GANP PF03399.16 XP_666997.1 - 0.086 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 SAC3/GANP family CS PF04969.16 XP_666998.1 - 1.7e-12 48.2 4.3 3e-12 47.4 4.3 1.4 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.11 XP_666998.1 - 0.00021 21.5 0.3 0.00052 20.3 0.3 1.8 1 0 0 1 1 1 1 Siah interacting protein, N terminal SGS PF05002.15 XP_666998.1 - 0.00074 19.6 0.2 0.0018 18.4 0.2 1.7 1 0 0 1 1 1 1 SGS domain HECT_2 PF09814.9 XP_667000.1 - 1.3e-05 24.2 7.7 1.9e-05 23.7 7.7 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 XP_667000.1 - 0.00083 19.5 2.3 0.0042 17.3 0.4 3.1 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 XP_667000.1 - 0.031 14.3 4.7 0.48 10.5 1.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 XP_667000.1 - 0.053 13.7 0.6 0.28 11.4 0.2 2.1 2 0 0 2 2 2 0 FYVE zinc finger Trypan_PARP PF05887.11 XP_667001.1 - 1.6e-08 34.6 65.6 4.5e-05 23.5 28.1 2.6 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Pre-PUA PF17832.1 XP_667002.1 - 2e-27 95.7 0.2 3.6e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 XP_667002.1 - 1.4e-18 66.6 0.1 1.9e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 XP_667002.1 - 0.012 15.9 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF1639 PF07797.14 XP_667004.1 - 0.12 12.4 0.5 0.45 10.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) Gp_dh_C PF02800.20 XP_667006.1 - 3.8e-66 221.5 0.0 5.3e-66 221.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 XP_667006.1 - 9.7e-40 135.0 0.0 2.1e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 XP_667006.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hexokinase_1 PF00349.21 XP_667007.1 - 6.3e-55 186.2 0.6 1.9e-54 184.6 0.0 1.9 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 XP_667007.1 - 1.2e-52 178.7 0.0 1.8e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FANCI_S2 PF14676.6 XP_667007.1 - 0.13 12.6 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 FANCI solenoid 2 NUDIX_2 PF13869.6 XP_667008.1 - 6.1e-57 192.3 0.0 8e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase Asp PF00026.23 XP_667009.1 - 3.4e-69 233.7 0.0 5.7e-69 232.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 XP_667009.1 - 4.1e-12 46.7 0.1 2e-08 34.7 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 XP_667009.1 - 0.0024 18.4 0.0 5.2 7.8 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Ras PF00071.22 XP_667010.1 - 2.8e-07 30.3 0.2 3.4e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Ras family DUF1327 PF07041.11 XP_667010.1 - 0.09 12.8 0.0 0.09 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) SET PF00856.28 XP_667011.1 - 0.00065 20.1 0.0 0.002 18.5 0.0 1.9 1 1 0 1 1 1 1 SET domain Lipoprotein_7 PF01540.16 XP_667011.1 - 0.013 14.8 1.3 0.04 13.2 0.2 2.0 2 0 0 2 2 2 0 Adhesin lipoprotein AF0941-like PF14591.6 XP_667011.1 - 2.5 8.7 5.8 2.8 8.5 0.4 3.2 3 0 0 3 3 3 0 AF0941-like FadA PF09403.10 XP_667011.1 - 6.6 7.3 7.1 1.5 9.4 0.1 3.2 4 0 0 4 4 4 0 Adhesion protein FadA Ribosomal_L7Ae PF01248.26 XP_667012.1 - 1.2e-24 85.9 0.2 1.5e-24 85.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 XP_667012.1 - 0.029 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain SNF2_N PF00176.23 XP_667013.1 - 5.2e-67 226.0 0.0 1e-66 225.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 XP_667013.1 - 3.1e-31 107.7 7.4 1.7e-30 105.4 4.0 3.1 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 XP_667013.1 - 5.1e-19 68.7 0.0 3.4e-18 66.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_667013.1 - 2.5e-13 50.4 0.0 1.2e-11 44.9 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_667013.1 - 5.4e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 XP_667013.1 - 0.00019 20.7 0.1 0.032 13.4 0.0 2.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 XP_667013.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.6 XP_667013.1 - 0.051 13.6 0.2 0.32 11.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain TrmO PF01980.16 XP_667014.1 - 1.3e-20 73.8 0.2 4.3e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 tRNA-methyltransferase O KLRAQ PF10205.9 XP_667015.1 - 0.00022 21.4 0.7 0.00022 21.4 0.7 2.0 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Phyto_Pns9_10 PF05878.11 XP_667015.1 - 0.048 12.8 0.6 0.049 12.8 0.6 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 ATP-synt_F PF01990.17 XP_667017.1 - 2.3e-28 98.4 0.3 2.6e-28 98.2 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PP2C PF00481.21 XP_667018.1 - 2.3e-30 106.1 0.0 2.5e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C rpo132 PF12415.8 XP_667018.1 - 0.039 13.2 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase VCBS PF13517.6 XP_667019.1 - 7.3e-22 77.7 13.7 5.4e-08 33.3 0.7 5.4 4 1 0 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 XP_667019.1 - 1.1e-15 57.4 7.7 0.0051 16.9 0.1 5.9 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 XP_667019.1 - 0.00023 20.6 0.0 15 4.9 0.0 5.1 6 0 0 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region Motile_Sperm PF00635.26 XP_667019.1 - 0.04 13.8 0.3 0.89 9.4 0.1 2.5 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Pkinase PF00069.25 XP_667020.1 - 1.1e-82 277.3 0.6 2.1e-82 276.5 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667020.1 - 1.5e-43 149.0 0.4 2.8e-43 148.1 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 XP_667020.1 - 1.7e-27 92.8 12.2 1.7e-06 27.1 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_667020.1 - 4.4e-27 94.3 20.5 9e-10 38.9 0.6 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 XP_667020.1 - 4.2e-22 76.1 7.8 6.4e-06 25.7 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 XP_667020.1 - 8e-20 70.5 12.1 7.1e-05 22.6 0.1 4.9 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_667020.1 - 4.3e-19 67.1 10.6 4.3e-06 26.0 0.2 4.6 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 XP_667020.1 - 7.1e-08 32.8 1.8 0.0015 18.9 0.2 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 XP_667020.1 - 4e-07 29.6 0.1 5.3e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 Kinase-like EF-hand_4 PF12763.7 XP_667020.1 - 2e-06 27.7 5.9 0.0021 18.0 0.7 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Pkinase_fungal PF17667.1 XP_667020.1 - 1.1e-05 24.4 0.1 2.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_667020.1 - 0.0013 18.1 0.1 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 XP_667020.1 - 0.0086 16.0 0.0 0.026 14.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_8 PF13855.6 XP_667021.1 - 4.3e-06 26.4 26.1 0.052 13.3 13.8 4.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 XP_667021.1 - 0.00013 22.2 34.4 0.079 13.4 8.4 5.3 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 XP_667021.1 - 0.00044 19.8 6.7 0.0056 16.2 3.2 2.9 1 1 1 2 2 2 2 Leucine-rich repeat SK_channel PF03530.14 XP_667021.1 - 0.08 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Calcium-activated SK potassium channel DUF974 PF06159.13 XP_667022.1 - 2.6e-17 63.5 0.1 6.6e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF974) DUF4352 PF11611.8 XP_667022.1 - 0.086 13.1 0.8 1.3 9.3 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4352) SVA PF05326.11 XP_667022.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Patched PF02460.18 XP_667023.1 - 1.3e-19 69.8 31.6 1.9e-12 46.2 15.3 3.5 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 XP_667023.1 - 1.5e-10 41.1 0.2 1.5e-10 41.1 0.2 3.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation HemY_N PF07219.13 XP_667023.1 - 3.8 7.7 6.1 4.5 7.5 0.1 3.5 4 0 0 4 4 4 0 HemY protein N-terminus Pox_LP_H2 PF03356.15 XP_667025.1 - 0.081 12.8 0.1 0.091 12.6 0.1 1.0 1 0 0 1 1 1 0 Viral late protein H2 Membralin PF09746.9 XP_667026.1 - 5.3 6.0 10.2 5.9 5.8 9.1 1.6 1 1 0 1 1 1 0 Tumour-associated protein GDE_C PF06202.14 XP_667027.1 - 2.2 7.2 6.0 0.14 11.1 0.3 1.8 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Edc3_linker PF16598.5 XP_667028.1 - 0.041 14.5 1.3 0.14 12.8 0.2 2.3 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 BAR PF03114.18 XP_667029.1 - 0.0031 17.2 6.3 0.0031 17.2 6.3 1.7 2 0 0 2 2 2 1 BAR domain XhlA PF10779.9 XP_667029.1 - 0.04 14.1 0.3 0.04 14.1 0.3 2.2 2 0 0 2 2 2 0 Haemolysin XhlA EMC3_TMCO1 PF01956.16 XP_667029.1 - 0.22 11.2 1.9 0.64 9.7 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SseC PF04888.12 XP_667029.1 - 5 6.6 5.0 7.4 6.1 5.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family AAA_11 PF13086.6 XP_667029.1 - 8.6 6.1 9.3 11 5.7 9.2 1.3 1 1 0 1 1 1 0 AAA domain Autophagy_N PF03986.13 XP_667031.1 - 9.6e-26 90.4 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 XP_667031.1 - 1.7e-18 67.0 0.2 3.4e-18 66.0 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 XP_667031.1 - 6.2e-10 38.4 0.8 1.4e-09 37.2 0.8 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-Nse PF11789.8 XP_667032.1 - 5.7e-10 38.9 0.7 1.1e-09 38.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Phage_glycop_gL PF11108.8 XP_667033.1 - 0.15 12.1 2.8 0.36 10.9 1.0 2.6 2 0 0 2 2 2 0 Viral glycoprotein L DUF3385 PF11865.8 XP_667033.1 - 0.41 10.5 2.8 12 5.8 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) GMC_oxred_C PF05199.13 XP_667035.1 - 1.3e-22 80.9 0.0 3.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 XP_667035.1 - 4.8e-21 75.4 0.1 3.7e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 XP_667035.1 - 5.3e-05 22.6 0.1 9e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 XP_667035.1 - 9.3e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 XP_667035.1 - 9.8e-05 22.8 0.3 0.001 19.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 XP_667035.1 - 0.00011 20.9 0.0 0.00017 20.2 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 XP_667035.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 XP_667035.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 XP_667035.1 - 0.00024 20.4 0.2 0.00063 19.1 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 XP_667035.1 - 0.00025 20.4 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 XP_667035.1 - 0.0015 17.6 0.2 0.0025 17.0 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 XP_667035.1 - 0.0017 17.2 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 XP_667035.1 - 0.0038 16.3 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 XP_667035.1 - 0.0052 16.2 0.1 0.0078 15.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4847 PF16139.5 XP_667035.1 - 0.0094 15.9 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4847) Pyr_redox_3 PF13738.6 XP_667035.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 XP_667035.1 - 0.089 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC_tran PF00005.27 XP_667038.1 - 8.4e-32 110.5 0.0 6e-16 59.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 XP_667038.1 - 1.2e-31 110.4 29.1 7.9e-25 88.0 6.6 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region MMR_HSR1 PF01926.23 XP_667038.1 - 1.6e-07 31.4 0.1 0.026 14.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 XP_667038.1 - 2.6e-06 26.7 0.7 0.022 13.8 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 XP_667038.1 - 3.6e-06 27.5 0.0 0.0011 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 XP_667038.1 - 6.7e-06 25.8 0.4 0.044 13.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 XP_667038.1 - 6.7e-06 25.6 0.0 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 XP_667038.1 - 3.7e-05 23.8 2.7 0.14 12.2 0.7 3.0 2 1 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 XP_667038.1 - 5.4e-05 23.5 0.2 0.072 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 XP_667038.1 - 6.2e-05 22.9 2.9 0.0071 16.2 0.2 4.2 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 XP_667038.1 - 8.3e-05 22.6 0.2 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 XP_667038.1 - 0.0001 22.2 0.9 0.016 15.1 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 XP_667038.1 - 0.00018 21.3 0.1 0.097 12.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 XP_667038.1 - 0.00023 21.3 5.2 0.0064 16.6 0.2 3.2 2 1 1 3 3 3 1 Helicase HerA, central domain AAA_18 PF13238.6 XP_667038.1 - 0.00046 20.7 1.9 4.2 7.9 0.0 4.2 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 XP_667038.1 - 0.00091 18.7 0.0 6 6.2 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI GvpD PF07088.11 XP_667038.1 - 0.0017 17.1 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_7 PF12775.7 XP_667038.1 - 0.0025 17.3 0.8 0.55 9.7 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 XP_667038.1 - 0.0035 17.5 0.0 2.4 8.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 XP_667038.1 - 0.0036 16.6 0.1 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 XP_667038.1 - 0.0041 16.7 1.2 0.087 12.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 XP_667038.1 - 0.0052 17.1 0.7 0.2 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 XP_667038.1 - 0.0094 16.3 1.2 0.56 10.6 0.0 3.1 3 0 0 3 3 2 1 RNA helicase TrwB_AAD_bind PF10412.9 XP_667038.1 - 0.011 14.7 0.5 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 XP_667038.1 - 0.012 14.9 0.7 4.8 6.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 XP_667038.1 - 0.012 15.4 3.6 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 XP_667038.1 - 0.013 15.2 0.0 4.3 7.0 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 XP_667038.1 - 0.015 15.3 0.6 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 XP_667038.1 - 0.017 14.1 0.2 0.77 8.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 XP_667038.1 - 0.03 13.8 7.2 1.7 8.1 0.1 3.7 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 XP_667038.1 - 0.041 14.3 0.1 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 XP_667038.1 - 0.051 12.9 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 XP_667038.1 - 0.052 13.3 0.1 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 XP_667038.1 - 0.06 12.9 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 XP_667038.1 - 0.085 12.6 0.1 6.8 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 XP_667038.1 - 0.088 13.0 1.8 0.98 9.7 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 XP_667038.1 - 0.093 12.0 3.2 1.8 7.9 0.0 3.0 3 0 0 3 3 3 0 AIG1 family AAA_5 PF07728.14 XP_667038.1 - 0.094 12.7 0.1 3.5 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 XP_667038.1 - 0.12 12.4 0.1 13 5.8 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 XP_667038.1 - 0.13 12.0 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.14 XP_667038.1 - 0.27 11.1 0.6 9.2 6.2 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ANAPC4_WD40 PF12894.7 XP_667039.1 - 5.9e-10 39.3 0.6 0.53 10.6 0.0 6.1 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 XP_667039.1 - 2.2e-09 37.7 6.8 0.64 11.0 0.6 7.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 XP_667039.1 - 0.0054 15.7 2.8 0.39 9.6 0.0 4.1 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1 PF00133.22 XP_667040.1 - 2.3e-179 597.5 0.1 9.1e-178 592.2 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 XP_667040.1 - 9.8e-30 103.5 0.2 9.8e-30 103.5 0.2 2.3 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 XP_667040.1 - 3.6e-15 55.6 3.6 9.5e-08 31.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 XP_667040.1 - 5.6e-07 29.2 0.2 1.4e-05 24.7 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 XP_667040.1 - 0.00079 18.9 0.2 0.018 14.4 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Coagulase PF08764.10 XP_667040.1 - 0.018 15.2 1.8 0.044 14.0 1.8 1.6 1 0 0 1 1 1 0 Staphylococcus aureus coagulase tRNA-synt_1b PF00579.25 XP_667040.1 - 0.083 12.2 0.1 0.66 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF4358 PF14270.6 XP_667040.1 - 6.5 7.1 6.8 18 5.7 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PA28_beta PF02252.18 XP_667041.1 - 1.1e-55 187.3 0.8 1.3e-55 187.0 0.2 1.4 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 XP_667041.1 - 0.031 14.3 0.1 0.099 12.7 0.0 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Babuvirus_MP PF07234.11 XP_667041.1 - 0.12 12.5 0.0 15 5.8 0.0 2.2 2 0 0 2 2 2 0 Movement and RNA silencing protein SNF2_N PF00176.23 XP_667042.1 - 1.5e-69 234.4 2.3 3.2e-69 233.3 2.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.13 XP_667042.1 - 2.5e-09 37.3 3.4 1.1e-08 35.2 3.4 2.2 1 0 0 1 1 1 1 HSA AAA_14 PF13173.6 XP_667042.1 - 0.56 10.2 0.0 0.56 10.2 0.0 3.5 5 0 0 5 5 5 0 AAA domain Pkinase PF00069.25 XP_667043.1 - 7.2e-61 205.9 0.5 4.4e-60 203.3 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667043.1 - 3.2e-22 79.1 0.6 2.5e-20 72.9 0.6 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 XP_667043.1 - 0.00024 20.8 0.1 0.072 12.7 0.0 2.6 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 XP_667043.1 - 0.00029 19.7 0.1 0.00041 19.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_667043.1 - 0.0023 17.4 0.0 0.0056 16.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 XP_667043.1 - 0.065 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 XP_667043.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Alpha_adaptinC2 PF02883.20 XP_667044.1 - 6.8e-07 29.6 0.0 3.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain CBFD_NFYB_HMF PF00808.23 XP_667045.1 - 5.7e-06 26.5 0.0 6.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 XP_667045.1 - 0.003 17.9 0.0 0.0036 17.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Aida_N PF08910.10 XP_667045.1 - 0.016 15.6 0.1 0.018 15.4 0.1 1.1 1 0 0 1 1 1 0 Aida N-terminus GATA PF00320.27 XP_667046.1 - 0.014 15.0 7.3 0.66 9.6 7.3 2.5 1 1 0 1 1 1 0 GATA zinc finger DUF4327 PF14217.6 XP_667046.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) UCH_1 PF13423.6 XP_667048.1 - 1.3e-23 84.2 0.0 4.2e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 XP_667048.1 - 1.8e-10 41.6 0.0 3.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 XP_667049.1 - 2e-06 28.4 2.6 0.0013 19.5 0.2 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Proteasom_Rpn13 PF04683.13 XP_667049.1 - 0.036 14.6 0.0 0.094 13.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2373 PF10180.9 XP_667050.1 - 0.064 13.1 0.4 2.3 8.1 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Glyco_transf_20 PF00982.21 XP_667051.1 - 3e-101 339.5 2.1 2.2e-88 297.0 0.5 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 XP_667051.1 - 1e-42 145.9 0.0 4e-26 91.6 0.0 3.1 2 1 0 2 2 2 2 Trehalose-phosphatase BUD22 PF09073.10 XP_667051.1 - 0.81 9.0 13.5 0.014 14.8 1.4 3.1 3 1 0 3 3 3 0 BUD22 SCIMP PF15050.6 XP_667051.1 - 1.4 9.3 5.0 0.58 10.6 1.1 2.4 2 0 0 2 2 2 0 SCIMP protein eIF-5_eIF-2B PF01873.17 XP_667053.1 - 4.1e-36 123.4 0.1 8.6e-36 122.4 0.1 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 XP_667053.1 - 1.9e-15 56.7 0.3 1.4e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Zip PF02535.22 XP_667053.1 - 9.3 5.4 8.2 0.15 11.2 0.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_L22e PF01776.17 XP_667054.1 - 3.2e-45 153.0 0.2 3.5e-45 152.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family MerB PF03243.15 XP_667054.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Alkylmercury lyase Cpn10 PF00166.21 XP_667056.1 - 7e-06 26.0 0.1 1e-05 25.5 0.1 1.3 1 1 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2383 PF09537.10 XP_667057.1 - 0.034 14.5 0.6 0.11 12.9 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) FAM75 PF14650.6 XP_667057.1 - 0.059 12.9 2.0 0.067 12.7 2.0 1.0 1 0 0 1 1 1 0 FAM75 family ARA70 PF12489.8 XP_667057.1 - 0.093 12.9 2.4 0.13 12.4 2.4 1.3 1 0 0 1 1 1 0 Nuclear coactivator Tyr-DNA_phospho PF06087.12 XP_667058.1 - 4.1e-66 223.6 1.5 5.2e-66 223.3 1.5 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 XP_667058.1 - 0.00033 20.5 0.2 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain RNase_PH PF01138.21 XP_667059.1 - 3e-13 50.4 0.4 1.5e-12 48.2 0.0 2.3 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 XP_667059.1 - 4.9e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2977 PF11192.8 XP_667059.1 - 0.035 14.2 0.7 0.068 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) EB1 PF03271.17 XP_667060.1 - 4.9e-10 39.5 2.6 1.1e-09 38.3 2.6 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 XP_667060.1 - 2.9e-08 33.8 0.2 2.9e-08 33.8 0.2 2.0 3 0 0 3 3 3 1 Calponin homology (CH) domain CH_2 PF06294.11 XP_667060.1 - 0.037 14.1 0.8 0.037 14.1 0.8 2.3 3 0 0 3 3 3 0 CH-like domain in sperm protein CDC50 PF03381.15 XP_667061.1 - 3.8e-18 66.0 6.0 2.4e-12 46.9 2.7 2.2 2 0 0 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.29 XP_667063.1 - 0.011 16.2 0.4 0.013 16.0 0.4 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 XP_667068.1 - 6.2e-15 56.2 1.4 6.2e-15 56.2 1.4 7.0 2 2 1 4 4 4 1 AAA domain SMC_N PF02463.19 XP_667068.1 - 7.5e-11 41.9 36.2 1.2e-09 37.9 36.2 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 XP_667068.1 - 3.9e-05 23.6 3.1 3.9e-05 23.6 3.1 4.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 XP_667068.1 - 0.00013 21.6 0.2 0.00039 20.1 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Jnk-SapK_ap_N PF09744.9 XP_667068.1 - 0.021 15.0 0.4 0.021 15.0 0.4 6.6 3 2 2 6 6 6 0 JNK_SAPK-associated protein-1 ABC_tran PF00005.27 XP_667068.1 - 0.19 12.3 0.1 0.19 12.3 0.1 5.5 4 2 0 5 5 5 0 ABC transporter EXS PF03124.14 XP_667069.1 - 6.2e-70 236.1 30.6 8.9e-70 235.6 30.6 1.2 1 0 0 1 1 1 1 EXS family KH_6 PF15985.5 XP_667071.1 - 1.5e-10 41.3 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 KH domain GST_C_3 PF14497.6 XP_667072.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MA3 PF02847.17 XP_667073.1 - 1.8e-18 66.5 1.4 3.6e-18 65.6 1.4 1.5 1 0 0 1 1 1 1 MA3 domain Ribonuc_red_lgN PF00317.21 XP_667073.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Ribosomal_L2_C PF03947.18 XP_667075.1 - 3.6e-43 146.8 3.4 5.3e-43 146.2 3.4 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 XP_667075.1 - 1.3e-14 53.9 0.3 4.7e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DDE_Tnp_1_6 PF13751.6 XP_667076.1 - 0.074 13.3 0.1 0.074 13.3 0.1 2.2 2 0 0 2 2 2 0 Transposase DDE domain ECSIT_C PF14784.6 XP_667076.1 - 0.32 11.3 2.8 0.4 11.0 0.0 2.6 3 1 0 3 3 3 0 C-terminal domain of the ECSIT protein XPG_I PF00867.18 XP_667077.1 - 2.7e-29 101.3 2.4 4.1e-29 100.8 0.1 2.6 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.17 XP_667077.1 - 4.3e-17 62.4 0.0 9.9e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 XP_667077.1 - 3.2e-07 30.8 0.0 1.6e-06 28.6 0.0 2.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 XP_667077.1 - 0.011 15.9 0.1 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif CDKN3 PF05706.12 XP_667077.1 - 0.03 14.0 0.0 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) EMP24_GP25L PF01105.24 XP_667078.1 - 1.4e-12 48.0 3.2 1.5e-12 47.9 3.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Fusion_F0 PF13044.6 XP_667078.1 - 0.16 10.6 0.2 0.17 10.5 0.2 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus PRP21_like_P PF12230.8 XP_667079.1 - 1.7e-59 201.3 10.2 2.6e-59 200.7 10.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 XP_667079.1 - 2.1e-34 117.3 0.5 3e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 Surp module FinO_N PF12602.8 XP_667079.1 - 0.066 13.5 0.4 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 Fertility inhibition protein N terminal IL5 PF02025.15 XP_667079.1 - 0.091 13.0 0.8 0.18 12.1 0.8 1.4 1 0 0 1 1 1 0 Interleukin 5 PAT1 PF09770.9 XP_667080.1 - 5.6 5.1 20.1 1.8 6.7 0.2 2.7 2 1 1 3 3 3 0 Topoisomerase II-associated protein PAT1 Guanylate_kin PF00625.21 XP_667082.1 - 5.9e-19 68.5 0.0 7.5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase Rad17 PF03215.15 XP_667082.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 XP_667082.1 - 0.00046 20.1 0.0 0.00058 19.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 XP_667082.1 - 0.0048 17.2 0.0 0.0058 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 XP_667082.1 - 0.0056 17.1 0.0 0.0078 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 XP_667082.1 - 0.012 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 XP_667082.1 - 0.021 15.3 0.0 0.027 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 XP_667082.1 - 0.024 15.2 0.0 0.028 14.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 XP_667082.1 - 0.027 14.6 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 XP_667082.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 XP_667082.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 XP_667082.1 - 0.15 12.5 0.0 0.19 12.2 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 XP_667082.1 - 0.2 11.9 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 XP_667082.1 - 0.21 11.5 0.0 0.28 11.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 XP_667082.1 - 0.23 11.2 0.1 0.34 10.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 XP_667082.1 - 0.31 10.6 0.0 0.42 10.2 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 XP_667084.1 - 4.2e-59 198.8 0.2 4.9e-59 198.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 XP_667084.1 - 3.7e-36 124.0 0.1 7e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 XP_667084.1 - 7.7e-17 61.3 0.0 1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 XP_667084.1 - 0.00033 20.1 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 XP_667084.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 XP_667084.1 - 0.0032 17.4 0.1 0.39 10.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 XP_667084.1 - 0.004 16.7 0.1 0.018 14.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 XP_667084.1 - 0.086 12.2 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 XP_667086.1 - 6e-14 52.6 0.1 2.2e-13 50.8 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 XP_667086.1 - 1.1e-12 48.1 0.0 8.3e-12 45.4 0.0 2.5 2 1 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 XP_667086.1 - 7.4e-12 45.3 0.7 1.8e-11 44.1 0.7 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 XP_667086.1 - 1.9e-10 41.0 0.0 3.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 XP_667086.1 - 7.2e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 XP_667086.1 - 1.9e-07 31.5 0.0 3.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 XP_667086.1 - 3.3e-06 27.1 3.1 0.0021 17.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 XP_667086.1 - 2.9e-05 24.5 0.0 0.00019 21.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 XP_667086.1 - 0.0002 21.7 0.2 0.00064 20.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 XP_667086.1 - 0.00026 21.0 0.1 0.0043 17.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PIF1 PF05970.14 XP_667086.1 - 0.0016 17.7 0.5 0.014 14.6 0.5 2.0 1 1 0 1 1 1 1 PIF1-like helicase DUF815 PF05673.13 XP_667086.1 - 0.0017 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 XP_667086.1 - 0.0019 18.0 0.1 0.0039 17.0 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 XP_667086.1 - 0.0023 18.0 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_667086.1 - 0.0032 17.3 0.4 0.022 14.5 0.4 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_3 PF07726.11 XP_667086.1 - 0.0048 16.8 0.1 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 XP_667086.1 - 0.0051 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_7 PF12775.7 XP_667086.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 XP_667086.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 XP_667086.1 - 0.016 15.7 0.2 0.036 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 XP_667086.1 - 0.017 15.6 0.4 2 9.0 0.0 3.0 2 1 1 3 3 3 0 ABC transporter DNA_pol3_delta PF06144.13 XP_667086.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 XP_667086.1 - 0.024 14.7 0.1 0.22 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 XP_667086.1 - 0.035 13.2 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 XP_667086.1 - 0.049 13.0 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 XP_667086.1 - 0.066 12.4 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 XP_667086.1 - 0.096 12.4 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 XP_667086.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.6 XP_667086.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 XP_667087.1 - 1e-10 41.5 0.0 3.9e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 XP_667087.1 - 0.24 11.3 0.0 0.41 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5640 PF18692.1 XP_667087.1 - 0.69 10.0 4.2 0.73 9.9 0.6 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Bromodomain PF00439.25 XP_667088.1 - 1.1e-20 73.5 3.1 1.6e-20 72.9 0.9 2.5 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 XP_667088.1 - 1e-11 45.1 0.1 2.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 XP_667088.1 - 7.2e-09 35.7 0.1 1.5e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 XP_667088.1 - 8.3e-07 29.3 0.7 1.7e-06 28.3 0.7 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 XP_667088.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 XP_667088.1 - 0.036 14.2 0.1 0.076 13.1 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arb1 PF09692.10 XP_667089.1 - 0.027 13.7 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PXA PF02194.15 XP_667090.1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 PXA domain LNS2 PF08235.13 XP_667093.1 - 4.6e-89 297.8 0.0 6.2e-89 297.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 XP_667093.1 - 4.2e-32 110.2 0.0 8.8e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 XP_667093.1 - 6.5e-15 55.1 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 XP_667093.1 - 0.088 12.4 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ARPC4 PF05856.12 XP_667094.1 - 1.4e-59 200.4 5.5 2.2e-59 199.8 5.5 1.3 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DNA_pol3_a_NII PF11490.8 XP_667095.1 - 1.8 8.5 8.0 0.76 9.7 4.9 1.9 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II NCBP3 PF10309.9 XP_667096.1 - 0.0064 16.3 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DUF3657 PF12394.8 XP_667096.1 - 0.012 16.2 0.4 0.012 16.2 0.4 1.9 2 0 0 2 2 2 0 Protein FAM135 RTX PF02382.15 XP_667096.1 - 0.03 14.0 0.5 0.038 13.7 0.5 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein PP_kinase_N PF13089.6 XP_667096.1 - 0.042 14.2 1.4 0.12 12.7 0.1 2.3 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain Baculo_PEP_C PF04513.12 XP_667096.1 - 0.048 13.7 0.9 0.73 9.9 0.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 XP_667097.1 - 0.00018 19.2 35.1 0.00049 17.8 35.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Rop-like PF05082.13 XP_667097.1 - 0.46 10.3 4.6 2.6 7.9 0.9 3.0 2 0 0 2 2 2 0 Rop-like EzrA PF06160.12 XP_667097.1 - 0.82 7.8 45.3 4.8 5.2 23.9 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 XP_667097.1 - 1.1 8.0 42.0 0.45 9.4 20.5 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Peptidase_M75 PF09375.10 XP_667097.1 - 1.2 8.6 4.4 1.5 8.2 2.3 2.2 1 1 0 1 1 1 0 Imelysin NPV_P10 PF05531.12 XP_667097.1 - 7 7.2 24.6 0.075 13.5 1.4 5.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 XP_667097.1 - 8 6.5 45.3 0.022 14.8 12.7 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PUB PF09409.10 XP_667098.1 - 2.6e-13 49.7 0.3 6.6e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 PUB domain AAA_11 PF13086.6 XP_667098.1 - 0.17 11.6 2.4 0.23 11.2 1.5 1.6 1 1 0 1 1 1 0 AAA domain COMPASS-Shg1 PF05205.12 XP_667098.1 - 5.7 7.7 8.9 1.8 9.3 0.6 3.0 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 P5CR_dimer PF14748.6 XP_667099.1 - 2.9e-22 78.9 0.0 3.7e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation PAN_4 PF14295.6 XP_667100.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 XP_667100.1 - 0.0016 18.4 0.0 0.0073 16.3 0.0 2.1 1 0 0 1 1 1 1 PAN domain Phage_TAC_9 PF10876.8 XP_667100.1 - 0.08 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC TRAPP PF04051.16 XP_667101.1 - 2.3e-11 43.6 0.1 2.5e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RE_LlaMI PF09562.10 XP_667102.1 - 0.0019 17.8 0.7 0.0021 17.7 0.7 1.0 1 0 0 1 1 1 1 LlaMI restriction endonuclease BTG PF07742.12 XP_667102.1 - 0.052 13.4 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 BTG family MVL PF12151.8 XP_667102.1 - 0.062 13.2 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Mannan-binding protein zinc_ribbon_16 PF17034.5 XP_667103.1 - 1.1e-10 41.7 7.6 2e-10 41.0 7.7 1.4 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 XP_667103.1 - 6.2e-06 25.8 9.6 7.7e-06 25.4 9.6 1.1 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 XP_667103.1 - 0.0076 16.5 4.5 0.082 13.2 4.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 XP_667103.1 - 0.012 15.9 6.6 0.012 15.9 6.6 1.5 1 1 0 1 1 1 0 Ring finger domain eIF-5_eIF-2B PF01873.17 XP_667104.1 - 3.3e-35 120.5 0.0 5.9e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 XP_667104.1 - 0.0076 16.6 0.1 0.017 15.5 0.1 1.7 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 XP_667104.1 - 0.061 12.8 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 XP_667104.1 - 0.18 11.7 1.8 0.36 10.8 1.8 1.4 1 0 0 1 1 1 0 Nudix N-terminal Acyl_transf_3 PF01757.22 XP_667105.1 - 4.6e-58 196.9 23.7 4.6e-58 196.9 23.7 2.1 2 0 0 2 2 2 1 Acyltransferase family DUF1772 PF08592.11 XP_667105.1 - 0.18 12.1 2.6 27 5.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Rcd1 PF04078.13 XP_667107.1 - 6.9e-119 395.9 0.5 8.2e-119 395.6 0.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sec23_trunk PF04811.15 XP_667108.1 - 1.9e-18 67.0 0.0 3.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 XP_667108.1 - 3e-17 63.1 0.0 1.2e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 XP_667108.1 - 1.8e-14 53.4 0.4 1.5e-13 50.4 0.4 2.3 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 XP_667108.1 - 2.6e-06 27.2 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF4551 PF15087.6 XP_667109.1 - 0.0015 17.5 7.5 0.0026 16.7 7.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) DUF4758 PF15950.5 XP_667109.1 - 0.29 11.4 4.0 0.69 10.3 4.0 1.6 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein Abhydrolase_2 PF02230.16 XP_667114.1 - 2.3e-29 102.8 0.0 2.8e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 XP_667114.1 - 0.0042 16.4 0.0 0.14 11.4 0.0 2.6 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 XP_667114.1 - 0.12 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.7 XP_667115.1 - 6.1e-21 74.8 0.1 7.3e-10 39.3 0.0 5.6 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 XP_667115.1 - 5.5e-12 44.8 0.7 1.3 9.8 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 XP_667115.1 - 7.1e-12 45.3 4.2 0.03 14.6 0.0 6.7 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 XP_667115.1 - 2.3e-10 40.8 0.4 0.035 14.7 0.0 6.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 XP_667115.1 - 2.4e-08 34.0 0.5 0.14 12.6 0.1 5.5 4 0 0 4 4 4 2 Ankyrin repeat SET PF00856.28 XP_667115.1 - 0.091 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 SET domain SIS PF01380.22 XP_667116.1 - 2.1e-46 157.0 1.7 1.4e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 XP_667116.1 - 1.5e-22 80.3 0.0 3.5e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 XP_667116.1 - 1.5e-17 63.7 0.0 2.8e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain bact-PGI_C PF10432.9 XP_667116.1 - 0.00012 22.1 0.0 0.00046 20.3 0.0 2.0 1 1 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain GATase_4 PF13230.6 XP_667116.1 - 0.008 15.1 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 XP_667116.1 - 0.065 13.2 4.1 9.9 6.2 0.1 3.6 2 2 1 3 3 3 0 SIS domain Mannosyl_trans PF05007.13 XP_667117.1 - 4.9e-54 183.9 25.6 6.3e-54 183.5 25.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) Neuropeptide_S PF14993.6 XP_667119.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide S precursor protein TSC22 PF01166.18 XP_667119.1 - 0.66 10.3 6.4 0.63 10.4 0.7 3.4 2 2 2 4 4 4 0 TSC-22/dip/bun family Pkinase PF00069.25 XP_667120.1 - 4.9e-60 203.1 0.0 2.9e-59 200.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667120.1 - 2.4e-32 112.2 0.0 3.5e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_667120.1 - 5.6e-07 29.2 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 XP_667120.1 - 0.00027 20.6 0.0 0.86 9.2 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 XP_667120.1 - 0.0038 16.1 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 XP_667120.1 - 0.02 14.8 0.0 0.086 12.7 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 XP_667120.1 - 0.14 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH2_2 PF14633.6 XP_667121.1 - 8.8e-29 100.5 0.0 2.2e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 XP_667121.1 - 3e-11 43.6 0.0 1.2e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 XP_667121.1 - 0.00036 21.0 20.9 0.00036 21.0 20.9 7.1 4 1 2 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.6 XP_667121.1 - 0.0025 18.3 0.5 0.0079 16.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 ABC_tran PF00005.27 XP_667122.1 - 1.2e-46 158.6 0.1 9.7e-23 81.2 0.0 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 XP_667122.1 - 1.3e-18 66.8 0.4 1.3e-18 66.8 0.4 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 XP_667122.1 - 1.3e-14 54.7 19.5 4.7e-07 29.9 0.2 4.7 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 XP_667122.1 - 7.7e-11 41.8 1.4 0.0039 16.7 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 XP_667122.1 - 8.5e-05 22.2 5.7 0.094 12.5 0.2 3.7 4 0 0 4 4 4 2 P-loop containing region of AAA domain AAA_22 PF13401.6 XP_667122.1 - 0.00011 22.5 0.3 0.11 12.8 0.3 3.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 XP_667122.1 - 0.00025 21.0 0.4 1.1 9.2 0.3 2.8 2 1 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 XP_667122.1 - 0.00043 20.4 6.8 6.1 6.9 0.1 4.4 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_16 PF13191.6 XP_667122.1 - 0.0012 19.3 0.0 2.3 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 XP_667122.1 - 0.0017 18.1 0.1 0.81 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 XP_667122.1 - 0.003 16.8 0.4 0.011 14.9 0.0 2.1 2 1 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 XP_667122.1 - 0.0036 17.3 1.1 3.1 7.7 0.4 2.7 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.6 XP_667122.1 - 0.004 17.5 0.3 0.066 13.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 XP_667122.1 - 0.0048 17.1 0.4 25 5.1 0.0 3.6 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 XP_667122.1 - 0.0053 16.5 0.1 0.0053 16.5 0.1 5.0 6 1 0 6 6 6 2 AAA ATPase domain T2SSE PF00437.20 XP_667122.1 - 0.0069 15.5 2.8 0.013 14.6 0.3 2.4 2 1 0 3 3 3 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 XP_667122.1 - 0.0085 16.2 0.0 1.4 9.0 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 XP_667122.1 - 0.0099 16.1 3.8 1.1 9.5 0.4 3.0 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 XP_667122.1 - 0.012 16.2 0.0 0.012 16.2 0.0 4.7 4 1 1 5 5 4 0 AAA domain AAA_33 PF13671.6 XP_667122.1 - 0.012 15.8 0.1 2.1 8.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 XP_667122.1 - 0.012 14.8 0.3 4.4 6.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 XP_667122.1 - 0.017 14.6 0.4 0.4 10.2 0.3 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 XP_667122.1 - 0.018 15.4 0.1 8 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 XP_667122.1 - 0.019 15.1 0.0 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 XP_667122.1 - 0.024 14.5 0.9 1.9 8.4 0.3 2.7 2 0 0 2 2 2 0 NTPase Phage_TAC_12 PF12363.8 XP_667122.1 - 0.036 14.5 0.1 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC AAA_18 PF13238.6 XP_667122.1 - 0.041 14.4 4.0 1.8 9.1 0.0 3.8 5 0 0 5 5 3 0 AAA domain AAA PF00004.29 XP_667122.1 - 0.058 13.8 0.2 4.9 7.6 0.0 3.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 XP_667122.1 - 0.1 12.0 0.9 0.27 10.6 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 XP_667122.1 - 0.13 12.1 0.1 4.2 7.3 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 XP_667122.1 - 0.38 10.3 1.8 11 5.6 0.4 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Vir_act_alpha_C PF10400.9 XP_667123.1 - 0.036 14.7 0.1 1 10.1 0.1 2.1 2 0 0 2 2 2 0 Virulence activator alpha C-term PRD PF00874.20 XP_667123.1 - 0.043 14.1 0.3 0.08 13.3 0.3 1.5 1 0 0 1 1 1 0 PRD domain DUF3038 PF11237.8 XP_667123.1 - 0.071 13.1 2.6 5.4 7.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) EspB PF05802.11 XP_667123.1 - 0.071 13.1 0.4 0.091 12.7 0.4 1.3 1 1 0 1 1 1 0 Enterobacterial EspB protein NAD_kinase PF01513.21 XP_667126.1 - 1.9e-56 191.4 0.0 2.9e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Dynamin_N PF00350.23 XP_667128.1 - 2.1e-12 47.4 3.3 2.3e-12 47.3 0.1 2.8 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 XP_667128.1 - 0.0011 19.0 0.0 0.0073 16.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2639 PF11121.8 XP_667128.1 - 0.061 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) GNAT_acetyltr_2 PF13718.6 XP_667129.1 - 1.9e-76 256.5 0.0 6.8e-76 254.6 0.0 1.9 1 1 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 XP_667129.1 - 5.7e-56 189.2 0.0 1.1e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 XP_667129.1 - 1.5e-35 123.0 1.0 4.4e-35 121.5 1.0 1.7 1 1 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 XP_667129.1 - 2.4e-26 91.5 0.0 6.1e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 XP_667129.1 - 0.031 14.5 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 XP_667129.1 - 0.14 12.1 0.1 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Pfk_N PF18468.1 XP_667129.1 - 0.18 12.2 2.1 0.43 11.0 0.0 2.6 4 0 0 4 4 4 0 Phosphofructokinase N-terminal domain yeast Acetyltransf_1 PF00583.25 XP_667130.1 - 1.3e-06 28.7 0.0 2.1e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 XP_667130.1 - 7.2e-05 23.1 0.1 0.00018 21.8 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 XP_667130.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 XP_667130.1 - 0.0041 17.1 0.1 0.019 14.9 0.0 2.1 3 1 1 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 XP_667130.1 - 0.0043 16.5 0.6 0.0043 16.5 0.6 1.7 2 0 0 2 2 2 1 Putative acetyl-transferase OGG_N PF07934.12 XP_667131.1 - 6.5e-34 116.6 2.3 1.4e-33 115.6 0.8 2.2 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 XP_667131.1 - 2e-07 31.4 0.0 4.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TBP PF00352.21 XP_667132.1 - 1.2e-53 179.0 0.0 1.4e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 XP_667132.1 - 0.019 15.1 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) BTB_2 PF02214.22 XP_667133.1 - 4.6e-13 49.3 0.2 4.6e-13 49.3 0.2 2.0 2 1 0 2 2 2 1 BTB/POZ domain TP2 PF01254.18 XP_667133.1 - 0.0043 17.7 11.8 0.0054 17.3 11.8 1.2 1 0 0 1 1 1 1 Nuclear transition protein 2 TFIIA PF03153.13 XP_667133.1 - 0.59 10.1 17.7 0.75 9.7 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 XP_667133.1 - 1.4 7.6 7.1 1.7 7.3 7.1 1.2 1 0 0 1 1 1 0 Presenilin Beach PF02138.18 XP_667135.1 - 1.2e-78 264.3 5.0 3e-78 263.0 5.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 XP_667135.1 - 0.063 13.4 1.7 6.1 7.0 0.4 4.1 2 1 0 2 2 2 0 PH domain associated with Beige/BEACH AMP-binding PF00501.28 XP_667136.1 - 2.1e-39 135.3 0.0 2.8e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF643 PF04867.12 XP_667136.1 - 0.003 18.2 0.3 0.012 16.2 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF643) RRM_1 PF00076.22 XP_667137.1 - 4.4e-49 164.2 0.1 8.5e-15 54.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_667137.1 - 9.3e-11 41.4 0.0 0.0057 16.3 0.0 3.5 2 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 XP_667137.1 - 4.9e-10 39.3 1.9 1.4e-09 37.9 1.9 1.8 1 0 0 1 1 1 1 WW domain RRM_7 PF16367.5 XP_667137.1 - 6.4e-09 35.8 0.2 0.013 15.6 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 XP_667137.1 - 0.00024 21.1 0.0 4 7.5 0.0 3.6 3 0 0 3 3 3 2 RNA binding domain Vps53_N PF04100.12 XP_667138.1 - 6e-19 68.2 26.1 1.3e-13 50.7 6.1 3.8 2 1 0 2 2 2 2 Vps53-like, N-terminal DNA_meth_N PF18284.1 XP_667138.1 - 0.13 12.2 0.2 5.7 6.9 0.0 2.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain Bromodomain PF00439.25 XP_667142.1 - 0.00032 20.7 0.4 0.0014 18.6 0.0 2.2 3 0 0 3 3 3 1 Bromodomain LMP PF04778.12 XP_667142.1 - 0.0066 16.4 1.2 0.019 14.9 1.2 1.7 1 0 0 1 1 1 1 LMP repeated region MRP-S31 PF15433.6 XP_667142.1 - 0.008 15.9 0.7 0.008 15.9 0.7 2.0 3 0 0 3 3 3 1 Mitochondrial 28S ribosomal protein S31 MTHFR_C PF12225.8 XP_667145.1 - 0.14 11.9 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal BOP1NT PF08145.12 XP_667146.1 - 7.6e-37 127.6 4.5 1.3e-36 126.9 4.5 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 XP_667146.1 - 2.3e-07 31.4 7.8 5.6 8.0 0.0 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667146.1 - 1.1e-05 25.7 0.2 8.1 6.8 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RCC1 PF00415.18 XP_667147.1 - 3.4e-32 110.8 0.1 4.7e-05 23.9 0.0 7.8 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 XP_667147.1 - 1.3e-19 69.4 14.6 0.00059 19.6 0.0 7.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Coilin_N PF15862.5 XP_667147.1 - 0.0055 16.5 1.3 0.0055 16.5 1.3 6.4 3 1 2 5 5 5 1 Coilin N-terminus zf-C3HC4_3 PF13920.6 XP_667148.1 - 1.5e-13 50.3 9.3 2.5e-13 49.7 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_667148.1 - 1.6e-07 31.1 11.8 3.1e-07 30.1 11.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 XP_667148.1 - 0.00018 21.8 13.6 0.00032 21.0 13.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 XP_667148.1 - 0.0013 18.6 11.2 0.0026 17.7 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ABC_tran PF00005.27 XP_667149.1 - 6.5e-12 46.1 0.1 4e-09 37.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 XP_667149.1 - 0.0068 16.2 3.3 14 5.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 XP_667149.1 - 0.066 13.8 0.7 0.36 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 XP_667149.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 XP_667149.1 - 0.19 11.6 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 XP_667150.1 - 1.7e-18 67.5 0.0 2.7e-09 37.6 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 XP_667150.1 - 3.1e-07 30.0 1.5 5.6e-05 22.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 XP_667150.1 - 0.0006 19.7 4.6 0.11 12.2 2.8 4.0 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 XP_667150.1 - 0.042 13.8 0.1 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 XP_667150.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 XP_667150.1 - 0.16 12.1 0.7 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 XP_667150.1 - 0.19 12.1 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 XP_667150.1 - 3.9 7.5 8.0 0.28 11.2 0.6 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 XP_667151.1 - 5.1e-10 40.0 2.7 1.4e-06 28.9 2.3 3.5 2 1 0 2 2 2 2 ABC transporter EBP PF05241.12 XP_667153.1 - 0.06 12.8 1.4 0.22 11.0 0.7 1.9 1 1 1 2 2 2 0 Emopamil binding protein RPN1_RPN2_N PF17781.1 XP_667154.1 - 5e-74 249.5 10.2 1.2e-73 248.3 10.2 1.6 1 1 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 XP_667154.1 - 1e-25 89.5 0.0 2e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 XP_667154.1 - 7.9e-17 60.8 12.5 3.3e-05 24.1 0.1 7.8 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 XP_667154.1 - 2.6e-07 31.0 0.0 0.048 14.1 0.0 3.9 2 1 1 3 3 3 3 HEAT repeats Cnd1 PF12717.7 XP_667154.1 - 0.038 14.0 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 XP_667154.1 - 0.069 13.4 0.0 0.67 10.4 0.0 2.9 1 0 0 1 1 1 0 HEAT repeat Ago_N_1 PF18351.1 XP_667154.1 - 0.2 12.1 0.5 11 6.6 0.0 2.6 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain HEAT_EZ PF13513.6 XP_667154.1 - 0.2 12.2 0.0 32 5.1 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat Abhydrolase_1 PF00561.20 XP_667155.1 - 9.5e-15 54.9 0.0 1.7e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 XP_667155.1 - 6.8e-14 51.7 0.0 1.5e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 XP_667155.1 - 1.1e-08 36.0 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 XP_667155.1 - 0.00013 21.7 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 XP_667155.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1100 PF06500.11 XP_667155.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 XP_667156.1 - 2.4e-18 66.3 0.0 4.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 XP_667156.1 - 1.4e-16 61.0 0.0 2e-09 37.5 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 XP_667156.1 - 6.2e-10 40.1 0.0 7.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 XP_667156.1 - 7.4e-06 25.7 0.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family UPF0227 PF05728.12 XP_667156.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 XP_667156.1 - 0.0098 15.5 0.0 0.069 12.7 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase FAM91_C PF14648.6 XP_667156.1 - 0.015 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 FAM91 C-terminus RFC1 PF08519.12 XP_667157.1 - 4.1e-37 127.8 0.5 1.4e-36 126.1 0.2 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 XP_667157.1 - 2.5e-15 56.6 0.0 8.2e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_pol3_delta PF06144.13 XP_667157.1 - 7e-10 39.0 0.1 2.7e-09 37.1 0.1 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 XP_667157.1 - 2.3e-08 34.5 0.0 8.8e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 XP_667157.1 - 6.2e-05 22.9 0.5 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain Rad17 PF03215.15 XP_667157.1 - 0.00016 21.7 1.3 0.0047 16.9 0.3 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 XP_667157.1 - 0.0019 18.7 0.2 0.016 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 XP_667157.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 XP_667157.1 - 0.011 16.2 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 XP_667157.1 - 0.017 15.1 0.0 0.065 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 XP_667157.1 - 0.026 14.7 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 XP_667157.1 - 0.027 14.8 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 XP_667157.1 - 0.051 13.9 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA C-terminal domain MutS_V PF00488.21 XP_667158.1 - 4e-71 239.0 0.1 7.6e-71 238.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 XP_667158.1 - 1.2e-32 112.5 0.0 3.2e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 XP_667158.1 - 2.6e-28 99.5 0.2 2.6e-28 99.5 0.2 2.7 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 XP_667158.1 - 6.1e-05 23.3 2.4 0.00022 21.5 2.4 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 XP_667158.1 - 0.0021 18.3 0.0 0.0092 16.3 0.0 2.2 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 XP_667158.1 - 0.09 12.4 0.1 15 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Defb50 PF17546.2 XP_667158.1 - 0.39 10.7 2.7 0.43 10.5 0.6 2.2 2 0 0 2 2 2 0 Beta defensin 50 vATP-synt_E PF01991.18 XP_667159.1 - 2.6e-57 193.5 8.7 2.9e-57 193.3 8.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Par3_HAL_N_term PF12053.8 XP_667159.1 - 0.022 14.9 0.2 0.022 14.9 0.2 2.0 2 1 0 2 2 2 0 N-terminal of Par3 and HAL proteins FNIP_M PF14637.6 XP_667159.1 - 0.03 14.3 0.3 0.038 14.0 0.3 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain NAD_binding_5 PF07994.12 XP_667159.1 - 0.057 12.8 1.6 0.088 12.2 1.1 1.6 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase Phasin_2 PF09361.10 XP_667159.1 - 0.3 11.4 4.6 0.48 10.7 4.6 1.3 1 0 0 1 1 1 0 Phasin protein tRNA-synt_2 PF00152.20 XP_667160.1 - 6.3e-84 281.7 0.0 1.3e-83 280.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 XP_667160.1 - 9.1e-06 25.6 0.1 2.2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 XP_667160.1 - 0.0016 17.9 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.7 XP_667160.1 - 0.2 11.3 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 tRNA_anti-like RNase_PH PF01138.21 XP_667161.1 - 0.00011 22.7 0.0 0.00011 22.7 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNA_pol_A_bac PF01000.26 XP_667165.1 - 3.4e-26 91.8 0.1 6.9e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 XP_667165.1 - 1.7e-21 75.4 0.0 2.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 XP_667165.1 - 0.0026 17.9 0.9 0.0064 16.6 0.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 XP_667165.1 - 0.017 15.7 1.6 0.043 14.4 1.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 XP_667165.1 - 0.024 14.7 1.4 0.024 14.7 1.4 2.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Metallophos PF00149.28 XP_667167.1 - 1.8e-12 48.2 0.2 3.1e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0239 PF06783.11 XP_667167.1 - 0.067 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) STATa_Ig PF18214.1 XP_667168.1 - 0.0011 18.9 0.4 0.0011 18.9 0.4 2.1 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain zf-RING_2 PF13639.6 XP_667169.1 - 1e-06 29.0 10.6 2.5e-06 27.7 10.6 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 XP_667169.1 - 0.00014 22.0 6.2 0.00035 20.7 6.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 XP_667169.1 - 0.00016 21.9 8.7 0.00049 20.3 8.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 XP_667169.1 - 0.00032 20.8 5.7 0.00084 19.4 5.7 1.8 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 XP_667169.1 - 0.0017 18.4 4.8 0.0042 17.1 4.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 XP_667169.1 - 0.004 16.7 6.2 0.0086 15.7 6.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_9 PF13901.6 XP_667169.1 - 0.0057 16.7 2.3 0.011 15.7 2.3 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 XP_667169.1 - 0.0078 16.5 8.7 0.017 15.4 8.7 1.6 1 1 0 1 1 1 1 RING-like domain zf-C3HC4_2 PF13923.6 XP_667169.1 - 0.21 11.5 10.5 0.61 10.0 10.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD_4 PF16866.5 XP_667169.1 - 0.38 10.9 10.8 2.4 8.3 0.3 2.9 1 1 1 2 2 2 0 PHD-finger zf-C3HC4 PF00097.25 XP_667169.1 - 0.63 10.0 15.3 0.11 12.4 11.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 XP_667169.1 - 1.1 9.1 4.4 2.6 7.9 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 XP_667169.1 - 3 7.8 6.6 6.9 6.7 6.6 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 XP_667169.1 - 5.4 7.0 8.6 0.98 9.4 4.4 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) KH_1 PF00013.29 XP_667170.1 - 0.00013 21.7 0.2 0.00035 20.3 0.2 1.7 1 0 0 1 1 1 1 KH domain Prefoldin_2 PF01920.20 XP_667171.1 - 0.19 11.7 0.2 0.19 11.7 0.2 6.3 5 1 2 7 7 7 0 Prefoldin subunit DUF1845 PF08900.11 XP_667171.1 - 0.98 9.1 3.9 4.1 7.1 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) ER_lumen_recept PF00810.18 XP_667172.1 - 3.3e-32 112.3 7.3 3.3e-32 112.3 7.3 2.3 3 0 0 3 3 3 1 ER lumen protein retaining receptor PsbH PF00737.20 XP_667172.1 - 0.029 14.1 0.5 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Mntp PF02659.15 XP_667172.1 - 0.039 13.7 1.4 0.087 12.6 1.4 1.6 1 0 0 1 1 1 0 Putative manganese efflux pump WD40 PF00400.32 XP_667173.1 - 9.5e-30 102.2 31.6 3.5e-06 27.6 0.5 12.9 13 1 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667173.1 - 9.2e-20 70.7 0.7 0.00091 19.5 0.0 9.4 5 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 XP_667173.1 - 2.3e-07 31.1 2.7 6.3e-07 29.7 2.7 1.8 1 1 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 XP_667173.1 - 8.2e-05 22.6 0.4 0.16 11.8 0.0 4.4 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 XP_667173.1 - 0.00011 21.3 0.3 3.4 6.5 0.0 4.4 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 XP_667173.1 - 0.0059 15.9 0.1 1.4 8.1 0.0 3.9 5 0 0 5 5 5 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 XP_667173.1 - 0.05 12.7 0.1 13 4.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) zf-C3HC PF07967.13 XP_667174.1 - 0.013 15.5 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 C3HC zinc finger-like BPL_LplA_LipB PF03099.19 XP_667175.1 - 5.4e-07 29.6 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family WD40 PF00400.32 XP_667176.1 - 4e-11 43.3 3.7 0.0088 16.9 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667176.1 - 1.8e-05 24.9 0.0 0.59 10.5 0.0 3.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Alpha-2-MRAP_C PF06401.11 XP_667177.1 - 0.0076 16.2 1.9 0.0091 16.0 1.9 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Prefoldin PF02996.17 XP_667177.1 - 0.017 15.0 1.7 0.051 13.5 0.5 2.0 2 0 0 2 2 2 0 Prefoldin subunit Prominin PF05478.11 XP_667177.1 - 0.032 12.2 2.8 0.038 12.0 2.8 1.1 1 0 0 1 1 1 0 Prominin POR PF01558.18 XP_667179.1 - 0.031 14.3 0.1 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Mur_ligase_M PF08245.12 XP_667179.1 - 0.062 13.3 1.0 0.17 11.8 0.2 2.0 1 1 0 2 2 2 0 Mur ligase middle domain Las1 PF04031.13 XP_667182.1 - 0.077 13.1 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Las1-like HMG_box PF00505.19 XP_667184.1 - 4.4e-15 55.9 4.7 4.4e-15 55.9 4.7 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 XP_667184.1 - 1.8e-09 38.0 4.9 3e-09 37.3 4.9 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 XP_667184.1 - 0.0027 17.7 0.2 0.0047 16.9 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 TSP_1 PF00090.19 XP_667185.1 - 9.5e-30 102.6 53.0 7.7e-11 42.0 5.3 4.5 4 0 0 4 4 4 4 Thrombospondin type 1 domain Kringle PF00051.18 XP_667185.1 - 5.1e-09 36.3 0.3 5.1e-09 36.3 0.3 2.5 2 0 0 2 2 2 1 Kringle domain OppC_N PF12911.7 XP_667185.1 - 0.13 12.3 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SecA_PP_bind PF01043.20 XP_667188.1 - 0.36 11.5 1.5 1 10.0 0.4 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Peptidase_S7 PF00949.21 XP_667189.1 - 0.21 11.4 0.7 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease ATP-synt_C PF00137.21 XP_667190.1 - 9.4e-30 102.8 32.4 4.7e-17 62.1 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2721 PF11026.8 XP_667190.1 - 6.8 6.6 10.4 0.27 11.1 3.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) ATP-synt_C PF00137.21 XP_667191.1 - 2.8e-28 98.0 38.2 4e-17 62.3 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PT-VENN PF04829.13 XP_667191.1 - 0.56 10.3 5.0 1.8 8.7 5.0 1.9 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif SHR3_chaperone PF08229.11 XP_667191.1 - 1.5 7.8 4.5 2.2 7.2 4.5 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 G0-G1_switch_2 PF15103.6 XP_667191.1 - 8.5 6.9 5.1 0.92 10.0 0.2 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Borrelia_P13 PF05628.12 XP_667192.1 - 0.34 10.9 1.1 0.91 9.5 0.8 1.8 2 0 0 2 2 2 0 Borrelia membrane protein P13 Exo5 PF09810.9 XP_667193.1 - 7.8e-56 190.1 6.7 3.5e-55 188.0 6.7 1.8 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PIN_4 PF13638.6 XP_667193.1 - 0.034 14.4 2.1 0.33 11.2 0.0 2.6 3 0 0 3 3 3 0 PIN domain PyrI PF01948.18 XP_667195.1 - 0.016 15.4 2.0 0.035 14.3 0.2 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain DUF4110 PF13422.6 XP_667196.1 - 0.05 13.7 2.7 0.16 12.0 2.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Synaptobrevin PF00957.21 XP_667196.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Synaptobrevin Exonuc_VII_L PF02601.15 XP_667196.1 - 0.87 9.1 5.9 9.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 XP_667196.1 - 2.2 6.1 3.3 3.7 5.3 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 XP_667196.1 - 4 7.5 6.7 1.4 8.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GP52 PF17468.2 XP_667197.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Phage gene product 52 Ribonuc_red_2_N PF08471.10 XP_667197.1 - 0.59 10.4 4.3 0.99 9.6 0.2 2.8 2 1 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Angiomotin_C PF12240.8 XP_667197.1 - 1 8.9 21.2 0.52 9.8 1.7 3.2 3 0 0 3 3 3 0 Angiomotin C terminal TAF6_C PF07571.13 XP_667199.1 - 0.0005 20.3 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 XP_667199.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Pkinase PF00069.25 XP_667202.1 - 9.5e-61 205.5 0.0 1e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667202.1 - 4e-33 114.8 0.0 4.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 XP_667202.1 - 1.6e-05 24.7 0.2 0.015 14.9 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 XP_667202.1 - 0.029 13.3 0.9 0.047 12.7 0.9 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 XP_667202.1 - 0.059 13.0 1.1 3.3 7.3 0.1 2.3 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 XP_667202.1 - 0.085 11.8 0.1 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 XP_667202.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPR_2 PF07719.17 XP_667203.1 - 2.7e-09 36.4 0.6 2.6e-05 24.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_667203.1 - 4.3e-08 32.7 4.1 4.1e-07 29.6 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_667203.1 - 0.0011 19.0 1.6 0.03 14.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Methyltransf_28 PF02636.17 XP_667203.1 - 0.0014 18.4 0.0 0.0053 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_12 PF13424.6 XP_667203.1 - 0.003 17.8 0.0 0.067 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_667203.1 - 0.0089 16.2 0.1 0.026 14.8 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 XP_667203.1 - 0.011 15.7 0.0 0.046 13.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667203.1 - 0.06 14.2 0.0 9.1 7.4 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Methyltransf_12 PF08242.12 XP_667203.1 - 0.1 13.4 0.0 1 10.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain TPR_17 PF13431.6 XP_667203.1 - 0.16 12.4 1.7 4.8 7.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat UAA PF08449.11 XP_667204.1 - 1e-44 153.0 27.5 2.9e-44 151.5 27.5 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 XP_667204.1 - 6.5e-08 32.8 11.0 6.5e-08 32.8 11.0 3.2 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 XP_667204.1 - 0.00078 18.9 15.9 0.038 13.3 5.9 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family PKD_channel PF08016.12 XP_667205.1 - 0.013 14.2 51.7 0.35 9.5 25.5 3.0 2 0 0 2 2 2 0 Polycystin cation channel Prenyltrans PF00432.21 XP_667208.1 - 1.5e-37 127.0 11.6 1e-11 44.4 0.4 5.3 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 XP_667208.1 - 1.9e-05 23.9 0.0 0.0081 15.3 0.0 2.3 1 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 XP_667208.1 - 3.6e-05 23.0 0.0 0.00074 18.6 0.0 2.5 2 1 1 3 3 3 1 A-macroglobulin TED domain EGF_CA PF07645.15 XP_667208.1 - 6.5 7.1 7.7 4 7.7 0.3 2.5 2 0 0 2 2 2 0 Calcium-binding EGF domain PI3_PI4_kinase PF00454.27 XP_667209.1 - 6e-36 124.5 0.1 1.5e-25 90.5 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 XP_667209.1 - 5.2e-23 81.4 2.1 1.7e-22 79.7 2.1 1.8 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF3546 PF12066.8 XP_667210.1 - 4.9e-22 78.2 1.9 7.1e-22 77.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 XP_667210.1 - 2.8e-10 40.9 0.7 5.7e-10 39.9 0.7 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Mrr_cat_2 PF13156.6 XP_667210.1 - 0.022 14.7 0.2 0.091 12.7 0.2 2.2 1 0 0 1 1 1 0 Restriction endonuclease DEAD PF00270.29 XP_667211.1 - 4.7e-24 85.1 0.0 9.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667211.1 - 6.6e-18 65.1 2.6 9.9e-18 64.5 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_667211.1 - 0.00019 21.5 0.0 0.00047 20.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ER-remodelling PF14755.6 XP_667215.1 - 8.4 6.7 12.0 1.1e+02 3.0 12.2 2.0 1 1 0 1 1 1 0 Intracellular membrane remodeller Nucleo_P87 PF07267.11 XP_667217.1 - 0.25 10.1 4.4 0.28 10.0 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 XP_667217.1 - 7 4.8 15.5 9.4 4.4 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 XP_667217.1 - 7.5 5.2 9.8 12 4.5 9.8 1.3 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 XP_667217.1 - 9.1 3.9 21.9 13 3.4 21.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Zip PF02535.22 XP_667217.1 - 9.3 5.4 6.8 16 4.6 6.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CoaE PF01121.20 XP_667220.1 - 3e-15 56.3 0.0 3.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase NPIP PF06409.11 XP_667220.1 - 0.063 12.3 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Arm PF00514.23 XP_667221.1 - 3.5e-11 42.7 0.1 0.012 15.6 0.0 4.8 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 XP_667221.1 - 0.042 13.4 0.6 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Atypical Arm repeat eIF2A PF08662.11 XP_667222.1 - 2.3e-33 115.7 4.6 1.4e-26 93.6 2.8 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 XP_667222.1 - 3.3e-06 27.3 1.5 5.2 7.4 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 XP_667222.1 - 4.6e-06 27.3 2.4 2 9.5 0.0 5.8 5 1 1 6 6 6 2 WD domain, G-beta repeat Pinin_SDK_memA PF04696.13 XP_667222.1 - 0.028 14.5 1.7 0.059 13.4 1.7 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF2024 PF09630.10 XP_667223.1 - 0.47 10.4 3.4 1.6 8.6 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2024) FYVE PF01363.21 XP_667223.1 - 1.9 8.7 12.5 2.1 8.5 0.3 3.7 4 0 0 4 4 4 0 FYVE zinc finger DUF1870 PF08965.10 XP_667223.1 - 2.3 8.2 7.5 19 5.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) WD40 PF00400.32 XP_667225.1 - 4.4e-29 100.1 19.6 2.2e-06 28.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667225.1 - 9.2e-16 57.9 0.0 0.02 15.2 0.0 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_667225.1 - 4.6e-06 26.2 0.0 1.6 8.0 0.0 4.5 3 2 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 XP_667225.1 - 2.5e-05 23.4 0.0 0.15 11.0 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 XP_667225.1 - 0.049 12.3 0.0 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SF-assemblin PF06705.11 XP_667226.1 - 9.3e-32 110.3 32.5 1e-31 110.2 32.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF4407 PF14362.6 XP_667226.1 - 0.0038 16.6 5.3 0.0038 16.6 5.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) E6 PF00518.17 XP_667226.1 - 0.071 13.6 0.6 0.19 12.2 0.6 1.7 1 0 0 1 1 1 0 Early Protein (E6) Exonuc_VII_L PF02601.15 XP_667226.1 - 0.1 12.2 17.4 1.4 8.4 5.7 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit HTH_WhiA PF02650.14 XP_667226.1 - 0.38 11.1 12.4 3.1 8.2 2.9 2.8 1 1 2 3 3 3 0 WhiA C-terminal HTH domain Baculo_PEP_C PF04513.12 XP_667226.1 - 0.67 10.0 10.8 1.9 8.5 3.1 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus partial_CstF PF15861.5 XP_667226.1 - 0.82 9.5 5.9 0.21 11.4 0.6 2.7 2 1 1 3 3 3 0 Partial cleavage stimulation factor domain RGS-like PF09128.11 XP_667226.1 - 1.1 9.0 19.4 0.77 9.4 8.9 2.0 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain ApoO PF09769.9 XP_667226.1 - 1.5 8.8 5.7 12 5.8 2.6 3.0 1 1 0 2 2 2 0 Apolipoprotein O XLF PF09302.11 XP_667226.1 - 1.9 8.6 15.1 0.89 9.7 4.2 2.6 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CorA PF01544.18 XP_667226.1 - 2.4 7.4 14.9 1.3 8.3 12.5 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Mis12 PF05859.12 XP_667226.1 - 3.8 7.6 16.0 0.4 10.7 9.6 2.2 2 0 0 2 2 2 0 Mis12 protein Nup54 PF13874.6 XP_667226.1 - 4.2 7.5 23.7 62 3.7 0.6 3.7 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 PIN_8 PF18476.1 XP_667226.1 - 7.7 6.3 22.2 36 4.1 15.3 2.5 1 1 1 2 2 2 0 PIN like domain CENP-L PF13092.6 XP_667226.1 - 7.7 6.7 6.9 58 3.8 6.8 2.3 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Ank_2 PF12796.7 XP_667227.1 - 2.1e-05 25.0 0.1 7.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 XP_667227.1 - 5.1e-05 23.4 0.0 0.01 16.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 XP_667227.1 - 0.00098 19.4 0.0 0.0044 17.3 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 XP_667227.1 - 0.019 15.4 0.0 0.19 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 XP_667227.1 - 0.033 14.8 0.0 1.3 9.7 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Neur_chan_memb PF02932.16 XP_667227.1 - 0.051 13.6 9.8 0.016 15.3 3.3 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 XP_667227.1 - 0.082 13.2 0.1 0.082 13.2 0.1 3.5 4 0 0 4 4 4 0 Orf78 (ac78) SLATT_5 PF18160.1 XP_667227.1 - 1.5 8.1 6.0 0.18 11.1 0.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Thioredoxin PF00085.20 XP_667228.1 - 2.8e-10 40.1 0.0 2.1e-06 27.7 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 XP_667228.1 - 0.00017 21.1 0.9 0.00091 18.7 0.1 2.5 4 0 0 4 4 4 1 OST3 / OST6 family, transporter family Ank_2 PF12796.7 XP_667229.1 - 4.2e-14 52.9 0.7 5.4e-06 26.9 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_667229.1 - 1.6e-12 47.6 2.2 0.00011 22.7 0.2 5.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 XP_667229.1 - 7.8e-07 29.3 0.4 0.0034 17.7 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 XP_667229.1 - 5.7e-06 26.5 1.6 4.7 7.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 XP_667229.1 - 9.2e-06 25.6 1.5 15 6.6 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat PdxJ PF03740.13 XP_667231.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ GPS PF01825.21 XP_667234.1 - 0.0079 16.7 0.7 0.0079 16.7 0.7 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Cbl_N2 PF02761.14 XP_667235.1 - 0.082 13.6 1.3 11 6.8 0.0 2.7 2 1 1 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Motile_Sperm PF00635.26 XP_667237.1 - 1.7e-23 82.6 0.0 3.6e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SOG2 PF10428.9 XP_667237.1 - 0.0016 17.7 0.9 0.0022 17.3 0.9 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein CENP-Q PF13094.6 XP_667237.1 - 0.032 14.4 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.18 XP_667237.1 - 0.04 14.1 3.6 0.077 13.2 3.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper EMP24_GP25L PF01105.24 XP_667237.1 - 0.066 13.2 1.0 0.11 12.4 0.8 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TMCO5 PF14992.6 XP_667237.1 - 0.22 11.1 4.1 0.46 10.0 3.6 1.7 1 1 1 2 2 2 0 TMCO5 family Rad10 PF03834.14 XP_667238.1 - 5.4e-37 126.3 0.1 7.9e-37 125.8 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 XP_667238.1 - 3.8e-09 36.5 0.0 8.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 XP_667238.1 - 4.6e-08 33.5 0.1 1e-07 32.4 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 XP_667238.1 - 5.9e-06 25.9 0.1 1.6e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 XP_667238.1 - 0.0038 17.4 0.0 0.063 13.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF790 PF05626.11 XP_667238.1 - 0.059 12.1 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Acid_PPase PF12689.7 XP_667238.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase DUF4148 PF13663.6 XP_667239.1 - 0.23 11.7 7.9 5.5 7.3 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Ribosomal_60s PF00428.19 XP_667239.1 - 0.57 10.8 14.9 2.9 8.5 5.5 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.15 XP_667239.1 - 0.63 10.9 9.8 2.3 9.1 2.2 3.1 2 0 0 2 2 2 0 Chorion family 2 RskA PF10099.9 XP_667239.1 - 0.74 10.1 16.2 0.11 12.8 0.8 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Golgin_A5 PF09787.9 XP_667239.1 - 3.3 7.1 10.3 5.4 6.4 10.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 MOZ_SAS PF01853.18 XP_667240.1 - 2.7e-72 242.2 0.0 4e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 XP_667240.1 - 1.1e-18 66.5 0.3 1.1e-18 66.5 0.3 2.2 3 0 0 3 3 3 1 MYST family zinc finger domain Tudor-knot PF11717.8 XP_667240.1 - 4.6e-14 52.0 0.1 1.3e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 XP_667240.1 - 0.0025 18.2 0.0 0.0065 16.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 XP_667240.1 - 0.0047 17.1 0.1 0.056 13.7 0.1 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family DUF1353 PF07087.11 XP_667240.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) PKcGMP_CC PF16808.5 XP_667241.1 - 0.11 12.4 1.5 0.32 10.9 1.5 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Flagellin_C PF00700.21 XP_667241.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region SOXp PF12336.8 XP_667241.1 - 0.62 11.2 2.9 2.4 9.3 2.2 2.4 1 1 0 1 1 1 0 SOX transcription factor TSC22 PF01166.18 XP_667241.1 - 1.5 9.2 4.9 0.61 10.4 0.3 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family BORCS6 PF10157.9 XP_667241.1 - 3.5 7.8 9.6 0.07 13.4 1.0 2.7 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 MORN PF02493.20 XP_667242.1 - 3.2e-94 303.5 95.1 1e-08 34.6 1.8 14.8 15 0 0 15 15 15 14 MORN repeat PA_decarbox PF05870.11 XP_667242.1 - 1.2 8.7 6.6 1.7 8.3 0.8 2.8 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) DUF2158 PF09926.9 XP_667242.1 - 10 6.0 9.6 33 4.3 0.0 5.6 3 2 2 6 6 6 0 Uncharacterized small protein (DUF2158) Nucleoporin_FG PF13634.6 XP_667243.1 - 0.16 12.9 49.9 0.081 13.8 9.1 5.5 3 1 1 4 4 4 0 Nucleoporin FG repeat region LUC7 PF03194.15 XP_667244.1 - 1.1e-59 202.1 7.5 1.1e-59 202.1 7.5 1.6 2 0 0 2 2 2 1 LUC7 N_terminus Nnf1 PF03980.14 XP_667244.1 - 0.031 14.6 0.2 0.079 13.3 0.2 1.7 1 0 0 1 1 1 0 Nnf1 ArfGap PF01412.18 XP_667245.1 - 1.3e-31 109.1 0.1 5.4e-31 107.1 0.1 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DnaJ PF00226.31 XP_667246.1 - 3.1e-25 88.1 1.0 6.4e-25 87.1 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 XP_667246.1 - 7.6e-15 54.8 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 XP_667246.1 - 4e-05 23.1 0.0 0.00018 21.0 0.1 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 XP_667246.1 - 0.0097 15.8 0.0 0.037 13.9 0.0 2.0 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 XP_667246.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain LSM14 PF12701.7 XP_667247.1 - 1e-20 73.6 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 XP_667247.1 - 2.8e-10 40.2 0.0 9.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 XP_667247.1 - 7.6e-06 26.8 8.3 7.6e-06 26.8 8.3 2.5 3 1 0 3 3 3 1 FDF domain LSM PF01423.22 XP_667247.1 - 9.7e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain DUF4403 PF14356.6 XP_667247.1 - 0.044 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) PGI PF00342.19 XP_667249.1 - 3.1e-171 570.3 0.0 3.8e-171 569.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 XP_667250.1 - 1.7e-71 240.7 0.0 2.1e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667250.1 - 6.3e-41 140.4 0.0 8.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_667250.1 - 0.00029 20.3 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 XP_667250.1 - 0.019 13.8 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 XP_667250.1 - 0.046 13.1 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 XP_667250.1 - 0.064 13.2 0.1 7.2 6.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rad17 PF03215.15 XP_667251.1 - 0.0019 18.1 0.0 0.0022 17.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 XP_667251.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 XP_667251.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 XP_667252.1 - 2e-07 30.9 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RabGAP-TBC PF00566.18 XP_667253.1 - 1.4e-38 132.7 4.1 1.4e-38 132.7 4.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fib_alpha PF08702.10 XP_667254.1 - 0.28 11.3 6.7 0.045 13.9 2.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3398 PF11878.8 XP_667255.1 - 0.035 14.5 1.1 0.93 9.9 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3398) PRP21_like_P PF12230.8 XP_667255.1 - 0.77 9.6 8.0 3.4 7.5 3.1 2.8 3 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Ribosomal_L32e PF01655.18 XP_667256.1 - 4.1e-47 159.1 0.2 5.4e-47 158.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 pKID PF02173.17 XP_667256.1 - 0.09 12.3 0.3 0.22 11.0 0.3 1.6 1 0 0 1 1 1 0 pKID domain IGR PF09597.10 XP_667256.1 - 0.11 12.6 1.9 5.3 7.2 0.7 2.9 3 0 0 3 3 3 0 IGR protein motif DUF202 PF02656.15 XP_667257.1 - 5.8e-15 55.5 1.2 1.2e-14 54.5 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 XP_667257.1 - 6e-11 42.9 13.2 8.4e-08 32.5 0.6 5.0 2 2 2 4 4 4 3 SPX domain DUF4199 PF13858.6 XP_667257.1 - 0.0058 17.0 0.4 0.014 15.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Exonuc_VII_L PF02601.15 XP_667258.1 - 0.078 12.5 5.0 0.093 12.3 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAS20 PF02064.15 XP_667258.1 - 0.084 13.0 14.8 0.16 12.1 14.8 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF2362 PF10154.9 XP_667258.1 - 0.092 11.7 8.0 0.11 11.4 8.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) LXG PF04740.12 XP_667258.1 - 0.14 11.8 10.7 0.35 10.6 10.6 1.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF4407 PF14362.6 XP_667258.1 - 0.33 10.3 5.1 0.41 9.9 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2207 PF09972.9 XP_667258.1 - 0.45 9.2 8.4 0.67 8.7 8.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Atg14 PF10186.9 XP_667258.1 - 1.1 8.2 11.6 1.4 8.0 11.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Goodbye PF17109.5 XP_667258.1 - 2.9 8.4 5.5 13 6.2 4.4 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Caldesmon PF02029.15 XP_667258.1 - 4.1 6.0 23.4 4.9 5.8 23.4 1.1 1 0 0 1 1 1 0 Caldesmon U79_P34 PF03064.16 XP_667258.1 - 6.8 6.0 14.9 9 5.6 14.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AAA_11 PF13086.6 XP_667258.1 - 7.1 6.3 10.5 8.9 6.0 10.5 1.1 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.24 XP_667259.1 - 1.3e-09 37.7 4.3 2.7e-09 36.7 4.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 XP_667259.1 - 5e-06 26.4 4.3 1.2e-05 25.2 4.3 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 XP_667259.1 - 0.0009 19.0 2.8 0.0009 19.0 2.8 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 XP_667259.1 - 0.018 15.5 2.6 0.041 14.4 2.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RNA_pol_Rpb1_5 PF04998.17 XP_667260.1 - 7.7e-92 307.5 0.4 1.6e-91 306.4 0.4 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 XP_667260.1 - 4.5e-74 249.6 0.0 4.5e-74 249.6 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 XP_667260.1 - 2.2e-72 242.7 0.0 5e-72 241.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 XP_667260.1 - 9.4e-37 126.4 0.0 3.9e-36 124.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 XP_667260.1 - 4.8e-30 103.7 0.0 2.6e-29 101.3 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CBM_48 PF02922.18 XP_667261.1 - 5.1e-22 78.0 0.3 8.6e-21 74.1 0.1 2.8 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 XP_667261.1 - 6.4e-18 65.0 0.2 5.7e-17 62.0 0.1 2.6 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 XP_667261.1 - 1.3e-10 41.4 2.8 0.00014 21.6 0.0 3.4 2 1 1 3 3 3 2 Alpha amylase, catalytic domain JAB PF01398.21 XP_667262.1 - 1.6e-32 111.9 0.0 3e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 XP_667262.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 XP_667262.1 - 1.3e-09 38.4 0.3 2.3e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 XP_667262.1 - 0.16 12.0 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Peptidase_C13 PF01650.18 XP_667264.1 - 1e-37 130.0 1.0 1.7e-37 129.3 1.0 1.4 1 0 0 1 1 1 1 Peptidase C13 family DUF5502 PF17606.2 XP_667264.1 - 0.11 13.2 1.1 0.64 10.8 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5502) Glycos_transf_1 PF00534.20 XP_667265.1 - 3.6e-29 101.5 0.0 2.9e-28 98.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 XP_667265.1 - 2.8e-12 47.2 0.0 7.1e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 XP_667265.1 - 0.0004 20.4 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 XP_667265.1 - 0.0043 17.4 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Inhibitor_I29 PF08246.12 XP_667265.1 - 0.52 10.8 2.2 1.5 9.3 0.2 2.4 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) DEAD PF00270.29 XP_667267.1 - 5.6e-43 146.7 0.0 2.8e-42 144.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667267.1 - 1.2e-29 102.9 0.4 7.1e-27 94.0 0.3 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 XP_667267.1 - 1.4e-08 34.9 0.0 9.5e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 XP_667267.1 - 0.069 13.4 2.5 0.33 11.2 0.6 3.1 2 1 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.6 XP_667269.1 - 2.6e-07 30.9 4.8 0.0068 17.1 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 XP_667269.1 - 4.3e-06 26.9 4.8 0.036 14.5 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 XP_667269.1 - 4.6e-06 26.8 7.5 4.6e-05 23.6 1.1 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 XP_667269.1 - 0.00015 21.6 3.6 0.0032 17.3 0.2 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 XP_667269.1 - 0.00043 20.6 2.7 0.32 11.4 0.2 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) LIM PF00412.22 XP_667269.1 - 0.01 16.0 2.4 0.014 15.7 2.4 1.2 1 0 0 1 1 1 0 LIM domain Rad50_zn_hook PF04423.14 XP_667269.1 - 0.014 15.3 1.2 0.061 13.2 0.1 2.0 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF2256 PF10013.9 XP_667269.1 - 0.12 12.5 3.2 2.5 8.3 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 XP_667269.1 - 0.33 11.4 5.2 11 6.6 5.2 2.1 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 XP_667269.1 - 0.47 10.4 5.4 2.8 7.9 0.9 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 XP_667269.1 - 1.8 8.6 8.3 0.87 9.7 2.3 2.3 1 1 1 2 2 2 0 BED zinc finger adh_short PF00106.25 XP_667271.1 - 3.6e-31 108.2 0.0 3.9e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 XP_667271.1 - 4.4e-17 62.4 0.0 1.1e-16 61.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 XP_667271.1 - 2.8e-08 33.9 0.0 4.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 XP_667271.1 - 0.096 12.1 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UCH PF00443.29 XP_667272.1 - 1.1e-43 149.6 0.5 1.4e-43 149.3 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_667272.1 - 4.7e-08 33.0 5.1 7.4e-06 25.8 5.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 XP_667272.1 - 2e-07 30.7 0.0 8e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family RE_NgoPII PF09521.10 XP_667272.1 - 0.0039 16.4 0.1 0.0067 15.6 0.1 1.3 1 0 0 1 1 1 1 NgoPII restriction endonuclease AP_endonuc_2 PF01261.24 XP_667273.1 - 2.1e-30 105.8 0.0 4.5e-30 104.7 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Oxysterol_BP PF01237.18 XP_667274.1 - 2.4e-107 359.0 2.4 2.4e-107 359.0 2.4 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein AAA PF00004.29 XP_667275.1 - 5.6e-94 311.6 0.0 8.8e-47 158.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 XP_667275.1 - 5.3e-28 96.6 6.7 3.4e-15 55.5 1.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 XP_667275.1 - 7.5e-22 77.3 0.2 2.1e-21 75.9 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 XP_667275.1 - 1.2e-13 51.1 0.0 7.9e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 XP_667275.1 - 7e-12 46.0 1.9 0.00089 19.7 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_2 PF07724.14 XP_667275.1 - 1e-11 45.2 0.0 3.3e-06 27.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 XP_667275.1 - 1.1e-10 41.7 0.1 1e-05 25.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 XP_667275.1 - 1.3e-10 40.9 0.0 3.4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 XP_667275.1 - 6.6e-10 39.3 0.0 9.6e-05 22.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 XP_667275.1 - 2.8e-08 34.1 1.5 0.036 14.3 0.1 4.6 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.13 XP_667275.1 - 6e-08 32.3 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 XP_667275.1 - 2.5e-07 31.3 0.0 0.033 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 XP_667275.1 - 6.1e-07 29.0 0.3 0.037 13.4 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 XP_667275.1 - 8e-07 29.4 0.0 0.028 14.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 XP_667275.1 - 9.5e-07 28.9 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 XP_667275.1 - 1.2e-06 28.2 0.4 0.53 9.8 0.0 3.6 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 XP_667275.1 - 5.7e-06 26.2 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 XP_667275.1 - 3.4e-05 23.9 0.0 0.57 10.1 0.0 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 XP_667275.1 - 5.1e-05 23.7 0.1 0.15 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 XP_667275.1 - 5.4e-05 23.1 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.12 XP_667275.1 - 5.8e-05 23.1 0.1 0.55 10.1 0.0 3.4 2 1 0 3 3 3 2 NACHT domain ATPase PF06745.13 XP_667275.1 - 6.5e-05 22.4 0.4 2.9 7.2 0.0 3.7 4 0 0 4 4 4 1 KaiC AAA_7 PF12775.7 XP_667275.1 - 7.1e-05 22.4 0.0 0.39 10.2 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 XP_667275.1 - 8.5e-05 22.9 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 XP_667275.1 - 0.0001 22.1 0.6 0.13 11.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.27 XP_667275.1 - 0.00012 22.6 0.0 0.44 11.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 XP_667275.1 - 0.00014 21.8 0.0 0.71 9.9 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 XP_667275.1 - 0.00018 21.3 0.0 0.3 10.8 0.0 3.2 2 2 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 XP_667275.1 - 0.0002 20.5 0.0 0.46 9.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 XP_667275.1 - 0.00029 20.7 0.0 0.03 14.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 XP_667275.1 - 0.00041 19.6 0.0 0.96 8.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 XP_667275.1 - 0.0013 18.1 0.0 0.94 8.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Vps4_C PF09336.10 XP_667275.1 - 0.0014 18.5 0.1 0.0084 16.1 0.0 2.3 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 XP_667275.1 - 0.0016 17.7 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 XP_667275.1 - 0.002 18.3 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 XP_667275.1 - 0.0028 17.2 0.3 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 XP_667275.1 - 0.0036 16.6 0.0 0.68 9.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 XP_667275.1 - 0.0041 17.1 0.0 1.1 9.1 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 XP_667275.1 - 0.0054 16.6 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 XP_667275.1 - 0.0082 16.2 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 XP_667275.1 - 0.011 16.1 0.3 6.6 7.1 0.1 3.2 3 1 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 XP_667275.1 - 0.018 14.9 1.4 7.9 6.4 0.0 3.7 4 0 0 4 4 3 0 NTPase AAA_30 PF13604.6 XP_667275.1 - 0.024 14.4 0.1 6.2 6.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 XP_667275.1 - 0.024 14.8 0.2 5.8 7.0 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family KAP_NTPase PF07693.14 XP_667275.1 - 0.043 13.1 0.1 2.4 7.3 0.0 3.1 2 2 2 4 4 4 0 KAP family P-loop domain AAA_29 PF13555.6 XP_667275.1 - 0.045 13.5 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 XP_667275.1 - 0.049 13.4 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 XP_667275.1 - 0.058 13.1 0.2 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 XP_667275.1 - 0.063 13.4 0.1 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Josephin PF02099.17 XP_667276.1 - 2.3e-42 144.9 1.1 7.9e-42 143.1 0.0 2.1 2 1 0 2 2 2 1 Josephin UBX PF00789.20 XP_667276.1 - 1e-06 28.8 0.2 6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 UBX domain JHY PF15261.6 XP_667276.1 - 0.00063 20.5 0.9 0.002 18.9 0.2 2.1 2 1 1 3 3 3 1 Jhy protein G10 PF01125.17 XP_667276.1 - 0.11 12.2 0.2 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 G10 protein Rad51 PF08423.11 XP_667277.1 - 2.5e-05 23.7 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 Cyclin_N PF00134.23 XP_667278.1 - 1.1e-10 41.3 1.8 1.1e-10 41.3 1.8 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 XP_667278.1 - 3.4e-05 23.9 2.3 4.7e-05 23.5 0.5 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DHHC PF01529.20 XP_667279.1 - 1.2e-30 106.4 19.3 1.2e-30 106.4 19.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase SET PF00856.28 XP_667280.1 - 2.9e-10 40.8 1.7 1.6e-09 38.4 0.1 2.7 2 1 0 2 2 2 1 SET domain RPN2_C PF18004.1 XP_667280.1 - 7.3 6.5 9.2 18 5.2 9.2 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PIGA PF08288.12 XP_667282.1 - 3e-41 139.9 1.8 7e-41 138.7 1.0 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 XP_667282.1 - 8.5e-28 97.5 0.1 2.4e-27 96.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 XP_667282.1 - 1.6e-27 96.2 0.0 2.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 XP_667282.1 - 8.3e-23 81.3 0.0 1.5e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 XP_667282.1 - 3.4e-09 37.4 0.0 5.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 XP_667282.1 - 0.00031 20.8 0.1 0.0011 19.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 XP_667282.1 - 0.049 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 NYD-SP28 PF14772.6 XP_667283.1 - 0.061 13.4 1.3 0.092 12.8 1.3 1.4 1 1 0 1 1 1 0 Sperm tail Lzipper-MIP1 PF14389.6 XP_667284.1 - 0.097 13.0 1.2 11 6.4 0.1 2.1 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Peptidase_C1 PF00112.23 XP_667285.1 - 1.8e-41 142.6 4.0 5.1e-41 141.2 4.0 1.7 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 XP_667285.1 - 5.1e-13 49.3 2.3 4.6e-07 30.1 1.2 3.3 2 1 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 XP_667285.1 - 0.074 11.8 2.9 0.049 12.4 0.7 1.7 2 0 0 2 2 2 0 Peptidase C1-like family PX PF00787.24 XP_667286.1 - 1.3e-22 79.9 0.2 3.3e-22 78.6 0.2 1.7 1 0 0 1 1 1 1 PX domain RabGAP-TBC PF00566.18 XP_667287.1 - 3.4e-22 79.2 0.6 3.4e-22 79.2 0.6 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CDT1 PF08839.11 XP_667289.1 - 5.8e-22 78.8 0.7 5.8e-22 78.8 0.7 3.1 3 1 0 3 3 3 2 DNA replication factor CDT1 like RNase_HII PF01351.18 XP_667290.1 - 1.5e-13 51.1 0.0 8.4e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease HII RNase_HII PF01351.18 XP_667291.1 - 2.4e-11 43.9 0.0 3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF3289 PF11692.8 XP_667292.1 - 0.0053 16.4 5.1 0.092 12.3 2.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3289) DUF4596 PF15363.6 XP_667296.1 - 1 9.6 4.0 8.2 6.7 4.0 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) RcbX PF02341.15 XP_667296.1 - 2 8.7 6.4 2.6 8.4 0.1 3.5 3 0 0 3 3 3 0 RbcX protein DUF4611 PF15387.6 XP_667296.1 - 5.5 7.3 7.5 29 5.0 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) CCDC-167 PF15188.6 XP_667296.1 - 9.3 6.7 30.8 0.21 11.9 2.1 5.9 5 0 0 5 5 5 0 Coiled-coil domain-containing protein 167 Tox-ART-HYD1 PF15633.6 XP_667297.1 - 0.011 16.4 0.1 0.019 15.6 0.1 1.4 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase SpoIISA_toxin PF14171.6 XP_667297.1 - 0.094 12.4 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Kazal_2 PF07648.15 XP_667298.1 - 1e-82 272.0 131.7 1.8e-10 40.7 5.3 13.8 14 0 0 14 14 14 13 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 XP_667298.1 - 4e-82 270.0 129.1 1e-09 38.2 4.5 13.8 14 0 0 14 14 14 13 Kazal-type serine protease inhibitor domain Tower PF09121.10 XP_667298.1 - 0.013 15.7 0.1 78 3.6 0.0 5.0 6 0 0 6 6 6 0 Tower DUF2095 PF09868.9 XP_667298.1 - 0.75 9.8 2.2 96 3.0 0.0 4.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2095) zf-C3HC4_3 PF13920.6 XP_667300.1 - 0.00038 20.3 6.8 0.00038 20.3 6.8 5.9 5 2 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 XP_667300.1 - 0.0017 17.6 4.3 0.0083 15.4 4.3 2.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF3877 PF12993.7 XP_667300.1 - 0.024 14.5 1.2 0.52 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Cir_N PF10197.9 XP_667301.1 - 1e-11 44.8 11.8 1e-11 44.8 11.8 2.0 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Slu7 PF11708.8 XP_667301.1 - 0.0012 18.6 13.2 0.0012 18.6 13.2 2.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor YebO PF13974.6 XP_667301.1 - 9.8 6.3 9.5 5 7.3 6.9 2.0 2 0 0 2 2 2 0 YebO-like protein Pkinase PF00069.25 XP_667302.1 - 8.5e-30 104.0 0.2 2.4e-29 102.5 0.2 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667302.1 - 1.3e-08 34.5 0.0 2.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4453 PF14627.6 XP_667303.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Csm2_III-A PF03750.13 XP_667304.1 - 0.016 16.0 1.3 0.025 15.4 1.3 1.2 1 0 0 1 1 1 0 Csm2 Type III-A PRIMA1 PF16101.5 XP_667304.1 - 0.017 15.2 7.5 0.026 14.6 7.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 YscO PF07321.12 XP_667304.1 - 0.037 14.0 1.3 0.051 13.5 1.3 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Baculo_PEP_C PF04513.12 XP_667304.1 - 0.038 14.0 0.8 0.11 12.5 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 XP_667304.1 - 0.064 13.3 7.6 0.057 13.5 3.4 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain NAS PF03059.16 XP_667304.1 - 0.08 12.3 2.8 0.1 11.9 2.8 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Syntaxin-6_N PF09177.11 XP_667304.1 - 0.1 13.2 2.0 0.16 12.5 2.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal ODC_AZ PF02100.17 XP_667304.1 - 0.18 11.8 0.7 0.28 11.2 0.7 1.3 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Hydantoinase_B PF02538.14 XP_667304.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase UL42 PF17638.2 XP_667304.1 - 1.5 8.8 8.9 2.4 8.1 8.9 1.3 1 0 0 1 1 1 0 HCMV UL42 Mito_fiss_reg PF05308.11 XP_667304.1 - 2.1 8.4 10.8 4.2 7.4 10.8 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator Tk-SP_N-pro PF18237.1 XP_667305.1 - 0.031 14.3 0.9 0.25 11.4 0.1 2.6 2 0 0 2 2 2 0 Tk-SP N-propeptide domain YniB PF14002.6 XP_667307.1 - 0.043 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 YniB-like protein Mucin PF01456.17 XP_667307.1 - 1.3 9.0 13.6 2.2 8.3 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Thioredoxin PF00085.20 XP_667310.1 - 3.7e-14 52.5 0.1 5.9e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 XP_667310.1 - 0.0025 18.2 0.4 0.014 15.8 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 XP_667310.1 - 0.016 15.5 0.8 0.033 14.5 0.2 1.9 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 XP_667310.1 - 0.032 14.4 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TIP49 PF06068.13 XP_667311.1 - 5.3e-153 509.3 3.0 5.3e-153 509.3 3.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 XP_667311.1 - 7.6e-22 77.2 1.7 1.9e-21 76.0 1.7 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 XP_667311.1 - 3.7e-11 43.6 0.4 2.6e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 XP_667311.1 - 3.1e-08 33.5 3.3 7.7e-05 22.5 0.1 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 XP_667311.1 - 1.6e-06 28.2 0.4 0.0023 17.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 XP_667311.1 - 2.6e-06 27.0 0.4 6.1e-06 25.8 0.4 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 XP_667311.1 - 6.5e-06 26.6 0.3 2.4e-05 24.8 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 XP_667311.1 - 2.9e-05 23.6 1.4 0.0077 15.6 0.3 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 XP_667311.1 - 6.9e-05 23.3 0.9 0.00025 21.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 XP_667311.1 - 9.2e-05 22.8 2.4 0.0021 18.4 2.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 XP_667311.1 - 0.00013 22.3 0.1 0.75 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 XP_667311.1 - 0.00013 21.7 0.3 0.1 12.3 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 XP_667311.1 - 0.0004 20.0 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 XP_667311.1 - 0.00051 19.4 0.1 0.0015 17.8 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 XP_667311.1 - 0.00068 19.5 0.1 0.038 13.8 0.1 2.8 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 XP_667311.1 - 0.00093 18.5 0.0 0.0024 17.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 XP_667311.1 - 0.0024 17.3 2.5 0.0039 16.6 1.6 1.8 1 1 1 2 2 2 1 KaiC NACHT PF05729.12 XP_667311.1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DNA_pol3_delta2 PF13177.6 XP_667311.1 - 0.0045 16.8 0.3 0.098 12.4 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 XP_667311.1 - 0.0062 16.8 0.2 0.087 13.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 XP_667311.1 - 0.0083 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TFIID-31kDa PF02291.15 XP_667311.1 - 0.011 15.8 0.6 0.026 14.6 0.6 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_30 PF13604.6 XP_667311.1 - 0.012 15.3 0.4 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 XP_667311.1 - 0.014 15.4 0.1 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 XP_667311.1 - 0.015 14.5 0.2 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.17 XP_667311.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 XP_667311.1 - 0.021 14.4 0.2 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 XP_667311.1 - 0.024 15.2 2.7 0.039 14.5 0.1 2.8 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 XP_667311.1 - 0.085 13.3 1.1 0.19 12.1 0.0 2.1 3 0 0 3 3 1 0 RNA helicase AAA_23 PF13476.6 XP_667311.1 - 0.16 12.5 7.4 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 XP_667311.1 - 0.73 9.8 4.1 4.5 7.2 0.1 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit WD40 PF00400.32 XP_667312.1 - 4.6e-14 52.6 0.6 4.6e-05 24.1 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667312.1 - 0.0074 16.6 0.0 7.7 6.9 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 XP_667312.1 - 0.045 12.7 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glycos_transf_2 PF00535.26 XP_667313.1 - 1.4e-28 99.8 0.0 2.7e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 XP_667313.1 - 1.6e-18 67.1 1.9 2.5e-18 66.6 1.9 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 XP_667313.1 - 3.5e-08 33.0 0.3 7.2e-08 32.0 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 XP_667313.1 - 0.0029 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RRM_1 PF00076.22 XP_667314.1 - 1.8e-36 123.7 0.0 3.2e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_667314.1 - 4.8e-10 39.4 0.0 0.00035 20.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 XP_667314.1 - 3.4e-05 23.8 0.1 0.087 12.8 0.0 2.7 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 XP_667314.1 - 0.077 13.2 0.0 15 5.8 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Laminin_G_1 PF00054.23 XP_667314.1 - 0.094 12.9 0.3 4.4 7.5 0.1 2.5 2 0 0 2 2 2 0 Laminin G domain CSD PF00313.22 XP_667314.1 - 0.21 11.4 0.3 13 5.8 0.0 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain YIF1 PF03878.15 XP_667315.1 - 2.1e-34 119.1 11.8 3e-34 118.6 11.8 1.2 1 0 0 1 1 1 1 YIF1 Choline_kinase PF01633.20 XP_667316.1 - 1.7e-42 145.4 1.2 1.7e-42 145.4 1.2 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 XP_667316.1 - 0.002 18.1 0.0 0.0033 17.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sec23_trunk PF04811.15 XP_667318.1 - 9e-64 215.3 0.0 1.3e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 XP_667318.1 - 6.2e-31 107.0 0.3 2.6e-30 105.0 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 XP_667318.1 - 1.3e-23 82.8 1.5 1.9e-23 82.2 0.3 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 XP_667318.1 - 2.1e-13 50.0 0.2 2.8e-12 46.3 0.3 2.6 2 1 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 XP_667318.1 - 2.3e-13 49.9 5.2 4.7e-13 48.9 5.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger KSHV_K1 PF11049.8 XP_667318.1 - 0.074 13.0 0.1 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus VP_N-CPKC PF11475.8 XP_667318.1 - 0.2 11.6 0.6 0.55 10.2 0.6 1.7 1 0 0 1 1 1 0 Virion protein N terminal domain Pkinase PF00069.25 XP_667319.1 - 3.7e-26 92.1 0.0 4.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667319.1 - 9.3e-17 61.2 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_667319.1 - 1.7e-09 37.0 0.0 2.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 XP_667319.1 - 0.00046 20.2 0.0 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 XP_667319.1 - 0.027 13.4 0.4 0.042 12.8 0.4 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SKG6 PF08693.10 XP_667319.1 - 0.11 12.0 1.5 0.36 10.3 1.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CAS_CSE1 PF03378.15 XP_667321.1 - 1.1e-38 132.9 3.2 1.1e-38 132.9 3.2 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 XP_667321.1 - 2.2e-38 132.0 3.3 1.8e-36 125.7 3.3 2.4 1 1 0 1 1 1 1 Cse1 IBN_N PF03810.19 XP_667321.1 - 1.7e-11 43.8 0.0 9.1e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Pfk_N PF18468.1 XP_667321.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Xpo1 PF08389.12 XP_667321.1 - 0.87 9.6 6.1 5.3 7.1 0.1 4.6 5 0 0 5 5 5 0 Exportin 1-like protein PI3K_1B_p101 PF10486.9 XP_667322.1 - 0.033 12.0 7.7 0.051 11.4 6.4 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dna2 PF08696.11 XP_667322.1 - 1.8 8.3 7.9 0.76 9.5 3.8 2.4 2 0 0 2 2 2 0 DNA replication factor Dna2 DUF3959 PF13105.6 XP_667322.1 - 5.9 6.3 8.1 17 4.8 8.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) AAA_32 PF13654.6 XP_667323.1 - 0.16 10.8 8.5 1.3 7.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain Cmc1 PF08583.10 XP_667324.1 - 0.031 14.3 1.0 0.07 13.2 1.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.6 XP_667324.1 - 0.091 13.0 0.4 0.23 11.8 0.4 1.6 1 0 0 1 1 1 0 YbfN-like lipoprotein ZapB PF06005.12 XP_667325.1 - 0.32 11.5 7.4 7.2 7.1 4.2 2.5 2 1 0 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 XP_667325.1 - 0.35 11.1 10.6 0.052 13.8 6.1 2.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 XP_667325.1 - 0.56 10.3 6.7 0.31 11.1 2.5 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 JIP_LZII PF16471.5 XP_667325.1 - 0.67 10.2 4.3 0.16 12.1 1.1 1.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DASH_Dad3 PF08656.10 XP_667326.1 - 0.0046 17.0 0.2 0.0046 17.0 0.2 1.8 2 0 0 2 2 2 1 DASH complex subunit Dad3 CBF PF03914.17 XP_667327.1 - 1.8e-22 80.2 0.1 1.8e-22 80.2 0.1 3.3 4 1 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 XP_667327.1 - 0.00062 19.8 0.7 0.00062 19.8 0.7 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_UF PF18817.1 XP_667327.1 - 0.047 14.0 0.8 0.37 11.1 0.0 2.7 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 RRM_1 PF00076.22 XP_667329.1 - 2.5e-09 36.8 0.2 5.7e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ELM2 PF01448.24 XP_667330.1 - 4.8e-07 30.4 0.0 8.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 ELM2 domain Patatin PF01734.22 XP_667331.1 - 7.3e-19 68.8 0.3 1.3e-17 64.7 0.3 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase EF-hand_1 PF00036.32 XP_667332.1 - 3.4e-20 70.0 5.0 1e-05 24.7 1.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 XP_667332.1 - 3.6e-18 63.9 3.3 1.5e-07 30.8 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 XP_667332.1 - 7.1e-16 58.4 4.8 1.1e-07 32.2 0.5 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 XP_667332.1 - 1e-14 54.1 5.4 8.5e-07 28.7 0.4 4.4 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 XP_667332.1 - 3.7e-12 45.2 2.4 8.3e-05 21.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 XP_667332.1 - 1.4e-07 31.7 0.9 0.16 12.3 0.0 3.8 3 1 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 XP_667332.1 - 0.0096 15.9 3.7 0.57 10.2 0.5 3.6 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand PEPCK_ATP PF01293.20 XP_667332.1 - 0.08 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Caleosin PF05042.13 XP_667332.1 - 0.089 12.7 0.8 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Caleosin related protein WD40 PF00400.32 XP_667333.1 - 9.2e-18 64.3 20.8 0.0011 19.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat IKI3 PF04762.12 XP_667333.1 - 0.0032 15.5 0.8 0.0061 14.6 0.7 1.4 1 1 0 1 1 1 1 IKI3 family BBS2_Mid PF14783.6 XP_667333.1 - 0.0055 16.7 0.0 4.6 7.3 0.0 3.5 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HA2 PF04408.23 XP_667334.1 - 9.8e-22 77.3 0.1 2.3e-21 76.1 0.1 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 XP_667334.1 - 3e-20 72.3 0.0 6.5e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 XP_667334.1 - 1.7e-12 47.6 0.0 5.7e-12 46.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 XP_667334.1 - 2.6e-08 33.9 1.0 2.5e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 XP_667334.1 - 4.3e-05 23.8 0.1 0.00015 22.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 XP_667334.1 - 0.0002 21.4 0.7 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 XP_667334.1 - 0.0026 18.1 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 XP_667334.1 - 0.0055 16.4 0.1 0.014 15.0 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 XP_667334.1 - 0.026 14.0 0.4 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 XP_667334.1 - 0.045 13.5 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 XP_667334.1 - 0.054 12.9 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 XP_667334.1 - 0.066 12.5 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 KaiC RasGEF_N PF00618.20 XP_667334.1 - 0.08 13.2 2.1 0.15 12.3 0.5 2.2 3 0 0 3 3 3 0 RasGEF N-terminal motif Zeta_toxin PF06414.12 XP_667334.1 - 0.1 11.8 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 XP_667334.1 - 0.13 11.9 0.2 0.56 9.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 XP_667334.1 - 0.15 12.6 0.4 0.4 11.2 0.0 1.9 2 0 0 2 2 1 0 ABC transporter TsaE PF02367.17 XP_667334.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 XP_667334.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 XP_667334.1 - 0.47 10.9 6.0 0.85 10.1 0.8 2.8 2 1 0 2 2 2 0 AAA domain Ribosomal_S19e PF01090.19 XP_667335.1 - 6.3e-51 171.7 0.0 7.1e-51 171.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pro_isomerase PF00160.21 XP_667336.1 - 9.6e-39 133.2 0.2 1.2e-38 132.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF441 PF04284.13 XP_667336.1 - 0.18 11.8 0.2 0.24 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF441) DEAD PF00270.29 XP_667337.1 - 3.8e-45 153.8 0.2 1.7e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667337.1 - 9.9e-32 109.6 0.8 4e-31 107.6 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_667337.1 - 2.7e-05 24.2 0.0 6.1e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 XP_667337.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 XP_667337.1 - 0.00031 20.2 0.2 0.00074 18.9 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 XP_667337.1 - 0.0017 18.7 0.2 0.042 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Pkinase PF00069.25 XP_667338.1 - 2.6e-31 108.9 0.1 1.1e-17 64.2 0.1 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667338.1 - 1.2e-15 57.5 0.0 1.4e-11 44.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase FTA2 PF13095.6 XP_667338.1 - 0.00058 19.6 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 XP_667338.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.21 XP_667338.1 - 0.07 13.1 2.4 10 6.3 0.1 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Pkinase_fungal PF17667.1 XP_667338.1 - 0.089 11.6 1.2 0.14 10.9 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase Pox_A14 PF05767.12 XP_667338.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 APH PF01636.23 XP_667338.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-A20 PF01754.16 XP_667339.1 - 3.3e-12 46.1 10.2 3.3e-12 46.1 10.2 2.9 4 0 0 4 4 4 1 A20-like zinc finger zf-AN1 PF01428.16 XP_667339.1 - 5.1e-09 36.1 11.4 5.1e-09 36.1 11.4 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Actin PF00022.19 XP_667340.1 - 6.6e-89 298.3 0.0 8.9e-88 294.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 XP_667340.1 - 0.00057 18.8 0.0 0.0035 16.2 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein ALP_N PF17989.1 XP_667340.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Actin like proteins N terminal domain LRR_9 PF14580.6 XP_667341.1 - 1.9e-16 60.1 3.3 8.7e-16 57.9 2.7 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 XP_667341.1 - 1.1e-06 28.8 17.1 0.00058 20.2 3.0 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 XP_667341.1 - 0.0016 18.2 13.0 0.016 14.9 4.9 3.4 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 XP_667341.1 - 1.3 9.2 3.5 16 5.9 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Ank_2 PF12796.7 XP_667343.1 - 0.0027 18.2 0.3 0.058 14.0 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF4690 PF15756.5 XP_667343.1 - 0.15 12.7 0.0 0.5 11.0 0.0 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DrrA_P4M PF14860.6 XP_667344.1 - 0.88 9.4 8.2 0.35 10.7 1.6 2.4 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF3591 PF12157.8 XP_667345.1 - 4.3e-37 127.8 0.0 6.4e-13 48.2 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF3591) Bromodomain PF00439.25 XP_667345.1 - 2.4e-14 53.1 0.3 6.4e-14 51.8 0.3 1.8 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 XP_667345.1 - 0.0014 18.4 1.2 0.0033 17.2 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 XP_667345.1 - 0.002 18.1 0.5 0.0044 17.0 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle UPF0113_N PF17833.1 XP_667346.1 - 1.6e-29 102.2 0.3 2.5e-29 101.6 0.3 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 XP_667346.1 - 1.3e-21 76.7 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Sortase PF04203.13 XP_667346.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 Sortase domain Tme5_EGF_like PF09064.10 XP_667347.1 - 1.3 9.0 29.5 0.44 10.5 0.1 8.4 8 2 2 10 10 10 0 Thrombomodulin like fifth domain, EGF-like cEGF PF12662.7 XP_667347.1 - 5.2 7.1 23.5 23 5.0 0.9 7.8 8 0 0 8 8 8 0 Complement Clr-like EGF-like EF-hand_1 PF00036.32 XP_667349.1 - 3.6e-05 23.0 0.4 0.02 14.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 XP_667349.1 - 0.00042 20.0 0.0 0.026 14.4 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 XP_667349.1 - 0.0005 20.5 2.4 0.069 13.6 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 XP_667349.1 - 0.024 14.1 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 EF hand FH2 PF02181.23 XP_667351.1 - 6.4e-76 255.9 0.2 1.1e-75 255.1 0.2 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_10 PF13374.6 XP_667351.1 - 3.2e-10 39.5 0.4 0.032 14.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 XP_667351.1 - 1.1e-09 38.4 0.1 5.5e-06 26.6 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_667351.1 - 0.009 15.8 8.5 4.6 7.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4167 PF13763.6 XP_667351.1 - 0.0097 16.0 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4167) TPR_2 PF07719.17 XP_667351.1 - 0.02 15.0 7.1 3.5 8.0 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ndc80_HEC PF03801.13 XP_667352.1 - 4.5e-27 94.6 0.0 1.6e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family Cluap1 PF10234.9 XP_667352.1 - 0.12 11.7 0.0 0.12 11.7 0.0 5.5 3 2 2 5 5 5 0 Clusterin-associated protein-1 DUF5601 PF18151.1 XP_667352.1 - 0.13 12.6 2.5 0.99 9.8 2.5 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) CIAPIN1 PF05093.13 XP_667353.1 - 7.1e-20 71.4 14.2 1.7e-18 67.0 14.2 2.3 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis LapD_MoxY_N PF16448.5 XP_667354.1 - 0.067 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain RED_N PF07808.13 XP_667355.1 - 1.6 8.3 17.3 5.2 6.6 17.3 1.9 1 0 0 1 1 1 0 RED-like protein N-terminal region Eryth_link_C PF16915.5 XP_667356.1 - 0.066 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus SRC-1 PF08832.10 XP_667358.1 - 0.079 14.0 2.5 0.25 12.4 2.5 1.9 1 0 0 1 1 1 0 Steroid receptor coactivator ATG16 PF08614.11 XP_667358.1 - 0.42 10.8 2.5 0.71 10.1 2.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AF-4 PF05110.13 XP_667358.1 - 1.8 6.5 17.1 2.4 6.1 17.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GST_C_3 PF14497.6 XP_667359.1 - 0.034 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 XP_667359.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 XP_667360.1 - 8.2e-20 71.7 0.3 4.1e-17 63.0 0.1 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 XP_667360.1 - 5.7e-10 39.3 41.3 4.8e-08 33.0 18.6 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region HAP2-GCS1 PF10699.9 XP_667362.1 - 1.9e-16 59.8 0.0 4e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Male gamete fusion factor RCC1_2 PF13540.6 XP_667363.1 - 6.5e-29 99.1 3.6 2.8e-08 33.3 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 XP_667363.1 - 2.9e-18 66.2 0.8 1.4e-05 25.6 0.0 7.1 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Actin PF00022.19 XP_667364.1 - 3.2e-125 417.9 0.0 3.6e-125 417.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 XP_667364.1 - 4.4e-06 25.7 0.0 0.0049 15.7 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 XP_667364.1 - 0.00077 19.8 0.1 3.9 7.9 0.0 3.0 3 0 0 3 3 3 2 Cell division protein FtsA Ribosomal_L6e_N PF03868.15 XP_667365.1 - 0.066 13.5 2.0 0.11 12.7 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain THP2 PF09432.10 XP_667365.1 - 0.1 12.6 5.3 0.14 12.2 3.5 1.8 1 1 1 2 2 2 0 Tho complex subunit THP2 COQ7 PF03232.13 XP_667365.1 - 0.19 11.5 2.4 0.33 10.7 2.0 1.5 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Pkinase PF00069.25 XP_667366.1 - 4.5e-55 186.8 3.8 4.5e-55 186.8 3.8 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667366.1 - 4e-37 127.9 0.7 4e-37 127.9 0.7 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_667366.1 - 4.4e-05 23.0 0.0 9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TFIIE_beta PF02186.15 XP_667366.1 - 0.67 10.3 6.2 30 5.0 0.2 4.3 4 0 0 4 4 4 0 TFIIE beta subunit core domain Histone_H2A_C PF16211.5 XP_667367.1 - 3.1e-18 65.2 0.7 6.1e-18 64.3 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 XP_667367.1 - 9.1e-18 64.9 0.0 1.3e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 XP_667367.1 - 9.7e-05 22.6 0.1 0.00017 21.8 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YdfA_immunity PF12127.8 XP_667367.1 - 0.095 11.8 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial PARG_cat PF05028.14 XP_667368.1 - 5.1e-51 174.0 0.0 6.7e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PCNA_N PF00705.18 XP_667369.1 - 4.3e-45 152.5 1.0 7.1e-45 151.8 1.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 XP_667369.1 - 6e-40 136.4 0.0 2.1e-39 134.6 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 XP_667369.1 - 2.4e-10 40.0 0.7 2e-06 27.1 0.4 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 XP_667369.1 - 0.00018 21.0 0.5 0.00021 20.8 0.5 1.2 1 0 0 1 1 1 1 Rad9 DNA_pol3_beta PF00712.19 XP_667369.1 - 0.0031 17.6 0.5 5.1 7.3 0.0 3.1 1 1 0 2 2 2 2 DNA polymerase III beta subunit, N-terminal domain Aha1_N PF09229.11 XP_667371.1 - 1.3e-15 57.8 0.1 1.3e-15 57.8 0.1 2.4 2 1 0 2 2 1 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 XP_667371.1 - 2.3e-13 49.1 2.0 9.5e-05 22.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 XP_667371.1 - 4.9e-12 45.3 1.1 0.0022 17.6 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.28 XP_667371.1 - 1e-11 44.1 4.7 5.8e-06 25.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 XP_667371.1 - 1.3e-07 31.8 2.2 0.064 13.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 XP_667371.1 - 4.8e-06 27.1 0.0 0.019 15.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 XP_667371.1 - 1.7e-05 24.8 0.8 0.035 14.2 0.1 3.5 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 XP_667371.1 - 2.5e-05 24.3 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_667371.1 - 2.9e-05 23.9 0.1 0.0041 17.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 XP_667371.1 - 0.00053 19.8 0.5 0.38 10.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 XP_667371.1 - 0.00083 19.6 0.0 2.8 8.5 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667371.1 - 0.0098 16.6 0.1 0.52 11.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 XP_667371.1 - 0.017 15.6 2.2 0.48 11.0 0.3 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 XP_667371.1 - 0.027 14.5 0.4 0.027 14.5 0.4 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 XP_667371.1 - 0.14 12.4 0.4 20 5.5 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MIR PF02815.19 XP_667373.1 - 2.5e-07 30.7 0.3 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 XP_667373.1 - 0.00021 20.6 1.6 0.023 13.9 0.4 2.4 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4564 PF15169.6 XP_667373.1 - 0.067 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) PX PF00787.24 XP_667375.1 - 1.3e-05 25.1 0.3 1.4e-05 25.0 0.3 1.0 1 0 0 1 1 1 1 PX domain BUD22 PF09073.10 XP_667376.1 - 0.17 11.2 21.0 0.2 10.9 21.0 1.2 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 XP_667376.1 - 0.31 11.2 15.3 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 XP_667376.1 - 2.9 6.4 10.9 4.1 5.9 10.9 1.4 1 1 0 1 1 1 0 Cell cycle and development regulator Flavodoxin_1 PF00258.25 XP_667377.1 - 3.1e-18 66.4 0.0 5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 XP_667377.1 - 3.2e-11 43.8 0.0 5.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 XP_667377.1 - 1.6e-09 37.7 1.0 7.5e-09 35.5 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_3 PF12641.7 XP_667377.1 - 0.015 14.9 0.2 0.061 13.0 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain LSM PF01423.22 XP_667378.1 - 0.00044 19.9 0.8 0.00068 19.3 0.8 1.3 1 0 0 1 1 1 1 LSM domain HDA2-3 PF11496.8 XP_667378.1 - 0.052 12.7 0.0 0.054 12.7 0.0 1.0 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 E1-E2_ATPase PF00122.20 XP_667379.1 - 1.6e-46 158.1 1.3 3e-46 157.2 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 XP_667379.1 - 2.1e-33 115.6 1.3 2.1e-33 115.6 1.3 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 XP_667379.1 - 7.9e-22 78.6 0.1 2.4e-16 60.7 0.1 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 XP_667379.1 - 2.9e-16 58.9 0.1 6.6e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 XP_667379.1 - 2.2e-08 34.1 5.4 2.4e-07 30.8 2.9 3.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 XP_667379.1 - 0.0018 18.0 0.9 0.0018 18.0 0.9 3.2 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2190 PF09956.9 XP_667379.1 - 0.017 15.6 1.0 0.056 13.9 1.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) HAD PF12710.7 XP_667379.1 - 0.021 15.2 0.0 0.13 12.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pox_A_type_inc PF04508.12 XP_667380.1 - 0.033 14.0 0.6 0.033 14.0 0.6 6.6 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Brix PF04427.18 XP_667381.1 - 4.6e-31 108.4 0.1 6e-31 108.1 0.1 1.1 1 0 0 1 1 1 1 Brix domain WD40 PF00400.32 XP_667382.1 - 1.7e-10 41.3 10.2 0.00017 22.3 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667382.1 - 1.5e-06 28.4 1.5 1.8e-05 24.9 0.2 3.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 XP_667382.1 - 0.0015 17.3 0.2 0.3 9.8 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 XP_667382.1 - 0.016 13.9 0.9 0.13 10.9 0.1 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MOZART1 PF12554.8 XP_667383.1 - 4.8e-17 61.5 2.7 5.7e-17 61.2 2.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Aa_trans PF01490.18 XP_667384.1 - 5.1e-30 104.5 30.6 6.6e-30 104.1 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DnaJ_C PF01556.18 XP_667385.1 - 1e-32 113.3 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 XP_667385.1 - 1.5e-26 92.3 1.6 2.8e-26 91.4 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 XP_667385.1 - 0.1 12.5 0.2 0.98 9.4 0.0 2.6 3 1 1 4 4 4 0 A repeated domain in UCH-protein CDP-OH_P_transf PF01066.21 XP_667386.1 - 1.4e-15 57.8 1.7 1.4e-15 57.8 1.7 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-LITAF-like PF10601.9 XP_667387.1 - 1.9e-14 53.7 4.6 1.9e-14 53.7 4.6 2.4 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain Rubredoxin PF00301.20 XP_667387.1 - 0.054 13.5 1.5 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin HypA PF01155.19 XP_667387.1 - 0.31 11.1 5.9 2.3 8.3 5.9 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 XP_667387.1 - 0.46 10.8 4.2 0.72 10.2 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Arf PF00025.21 XP_667389.1 - 1e-62 210.7 0.0 1.2e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 XP_667389.1 - 2.8e-13 49.8 0.5 5.9e-10 38.8 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 XP_667389.1 - 1.5e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 XP_667389.1 - 2.1e-09 37.2 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 XP_667389.1 - 4.4e-09 36.6 0.0 1.1e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 XP_667389.1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 XP_667389.1 - 5.5e-06 25.9 0.0 5.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 XP_667389.1 - 0.0013 18.3 0.0 0.025 14.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 XP_667389.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NOG1 PF06858.14 XP_667389.1 - 0.17 11.7 0.1 0.5 10.2 0.1 1.8 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Abhydrolase_6 PF12697.7 XP_667390.1 - 2.1e-05 25.2 0.0 2.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 XP_667390.1 - 4.9e-05 23.6 0.2 0.0035 17.5 0.1 3.3 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 XP_667390.1 - 0.001 18.8 0.4 0.046 13.4 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 XP_667390.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA PF00004.29 XP_667391.1 - 1.6e-10 41.5 0.0 5.3e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 XP_667391.1 - 4.5e-07 30.2 0.0 2.1e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 XP_667391.1 - 7.1e-07 29.4 1.4 1.3e-06 28.5 1.4 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 XP_667391.1 - 1.2e-06 29.0 0.0 3.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 XP_667391.1 - 0.0015 18.9 0.0 0.0041 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 XP_667391.1 - 0.0016 18.0 0.5 0.081 12.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 XP_667391.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 XP_667391.1 - 0.011 15.8 0.4 0.36 10.9 0.4 2.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 XP_667391.1 - 0.012 15.5 0.2 0.042 13.7 0.1 2.1 2 1 0 2 2 2 0 NTPase PIF1 PF05970.14 XP_667391.1 - 0.019 14.2 0.0 0.051 12.7 0.0 1.7 1 0 0 1 1 1 0 PIF1-like helicase UvrD-helicase PF00580.21 XP_667391.1 - 0.032 13.7 0.6 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_lid_10 PF17872.1 XP_667391.1 - 0.04 14.0 0.3 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA lid domain AAA_11 PF13086.6 XP_667391.1 - 0.047 13.5 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 XP_667391.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 XP_667391.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 XP_667391.1 - 0.099 13.2 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 XP_667391.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain eIF-5a PF01287.20 XP_667392.1 - 4.1e-23 81.3 0.0 6.1e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 XP_667392.1 - 0.0062 16.5 0.1 0.009 16.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Fcf1 PF04900.12 XP_667393.1 - 9.5e-37 125.4 1.5 1.1e-36 125.2 1.5 1.0 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 XP_667393.1 - 1e-07 32.3 0.0 1.1e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 XP_667393.1 - 0.057 13.7 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 NTF2 fold immunity protein GCV_T PF01571.21 XP_667393.1 - 0.17 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain ubiquitin PF00240.23 XP_667394.1 - 5.3e-35 119.0 0.3 6.9e-35 118.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 XP_667394.1 - 2.4e-29 101.0 9.6 3.7e-29 100.4 9.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 XP_667394.1 - 4.5e-17 61.6 0.4 7.5e-17 60.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 XP_667394.1 - 5.6e-06 26.7 0.1 2e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 XP_667394.1 - 0.0034 17.3 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 XP_667394.1 - 0.004 17.2 0.0 0.0081 16.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 XP_667394.1 - 0.0064 16.8 0.0 0.0099 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 XP_667394.1 - 0.022 14.8 0.7 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 XP_667394.1 - 0.047 14.2 0.0 0.055 14.0 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain ABC_sub_bind PF04392.12 XP_667395.1 - 0.01 15.1 1.8 0.016 14.5 1.8 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein DUF1682 PF07946.14 XP_667396.1 - 1.1e-67 228.5 4.5 1.3e-67 228.3 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_S3_C PF00189.20 XP_667397.1 - 5.7e-26 90.8 2.2 1.4e-25 89.6 1.3 2.1 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 XP_667397.1 - 1.5e-09 37.6 0.1 2.4e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 KH domain UTP15_C PF09384.10 XP_667404.1 - 5.2e-13 48.9 2.4 1.1e-12 47.9 2.4 1.5 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 XP_667404.1 - 3.4e-10 40.1 0.3 0.032 14.5 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 XP_667404.1 - 2.1e-09 37.8 4.3 0.044 14.7 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Utp13 PF08625.11 XP_667404.1 - 0.049 13.5 0.6 0.24 11.3 0.5 2.3 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain PARG_cat PF05028.14 XP_667405.1 - 0.00065 19.1 0.3 0.00087 18.7 0.3 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF4128 PF13554.6 XP_667405.1 - 0.047 13.8 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function UMP1 PF05348.11 XP_667406.1 - 1.2e-11 44.8 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Nkap_C PF06047.11 XP_667407.1 - 2.3e-43 146.4 4.3 2.3e-43 146.4 4.3 1.9 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain UQ_con PF00179.26 XP_667408.1 - 6.8e-48 161.9 0.0 7.6e-48 161.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 XP_667408.1 - 0.0094 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 XP_667408.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 XP_667408.1 - 0.031 14.6 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 RWD domain REPA_OB_2 PF16900.5 XP_667409.1 - 6.4e-26 90.1 0.2 8.4e-23 80.1 0.1 2.6 2 0 0 2 2 2 2 Replication protein A OB domain Rep_fac-A_C PF08646.10 XP_667409.1 - 1.3e-21 76.9 3.5 3.1e-21 75.7 3.5 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 XP_667409.1 - 6.4e-07 29.3 0.3 2.3e-05 24.3 0.1 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF5088 PF17008.5 XP_667409.1 - 0.0057 16.4 1.5 0.0092 15.7 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5088) SSB PF00436.25 XP_667409.1 - 0.0069 16.4 0.2 6.3 6.9 0.0 3.0 2 1 0 2 2 2 2 Single-strand binding protein family DZR PF12773.7 XP_667409.1 - 1 9.4 3.4 2.4 8.3 3.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon Proteasome PF00227.26 XP_667410.1 - 4e-47 160.2 0.3 5.2e-47 159.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 XP_667410.1 - 7.2e-14 51.1 0.1 1.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF507 PF04368.13 XP_667410.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Asp_protease PF09668.10 XP_667411.1 - 3.5e-57 191.6 1.1 4.5e-57 191.2 0.2 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 XP_667411.1 - 6e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 XP_667411.1 - 5.1e-09 36.7 0.0 9.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 XP_667411.1 - 4.6e-08 32.8 0.0 9.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 XP_667411.1 - 1.3e-05 25.0 0.1 2.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 XP_667411.1 - 6.2e-05 22.6 0.4 6.2e-05 22.6 0.4 1.7 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) RVP PF00077.20 XP_667411.1 - 0.00029 21.1 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.23 XP_667411.1 - 0.021 14.6 0.2 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin family UBA_4 PF14555.6 XP_667411.1 - 0.077 12.8 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 UBA-like domain KR PF08659.10 XP_667412.1 - 1.7e-96 321.3 0.0 3.8e-61 206.1 0.0 3.5 3 0 0 3 3 3 2 KR domain ketoacyl-synt PF00109.26 XP_667412.1 - 9.5e-76 254.7 0.0 3e-75 253.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 XP_667412.1 - 1.9e-60 204.2 0.0 3.8e-58 196.7 0.0 2.6 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 XP_667412.1 - 5.6e-46 157.5 0.0 8.9e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 XP_667412.1 - 8.1e-40 135.5 0.0 1.8e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 XP_667412.1 - 7.3e-28 96.7 1.0 1.3e-16 60.7 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 XP_667412.1 - 1.3e-21 76.9 0.0 5.8e-20 71.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 XP_667412.1 - 2e-15 56.8 0.8 8.7e-12 44.9 0.0 4.1 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.6 XP_667412.1 - 1.1e-14 54.4 0.0 6.7e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.21 XP_667412.1 - 2.3e-14 53.5 0.0 9.4e-08 31.8 0.0 3.0 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 XP_667412.1 - 1.8e-13 50.6 0.5 1e-10 41.6 0.0 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 XP_667412.1 - 8.9e-09 36.5 0.0 3.1e-08 34.8 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 XP_667412.1 - 2.8e-08 34.2 0.0 7.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension 3Beta_HSD PF01073.19 XP_667412.1 - 9.1e-07 28.2 0.1 0.00038 19.5 0.1 3.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.12 XP_667412.1 - 1.6e-05 24.7 0.4 6.1e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 XP_667412.1 - 2.1e-05 24.1 0.0 0.026 13.9 0.0 2.9 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 XP_667412.1 - 0.00013 21.2 0.3 0.00039 19.7 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 XP_667412.1 - 0.0002 20.8 0.1 0.00047 19.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sulfotransfer_3 PF13469.6 XP_667412.1 - 0.18 12.2 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase family RFC1 PF08519.12 XP_667412.1 - 0.23 11.6 3.8 0.65 10.1 0.4 2.8 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain PPDK_N PF01326.19 XP_667413.1 - 0.044 13.0 0.1 0.87 8.8 0.0 2.0 1 1 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Rotamase_3 PF13616.6 XP_667414.1 - 0.023 15.3 1.1 0.035 14.6 1.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain C2 PF00168.30 XP_667415.1 - 1.4e-28 99.2 1.7 6.1e-05 23.3 0.0 6.8 7 0 0 7 7 7 4 C2 domain Ferlin_C PF16165.5 XP_667415.1 - 0.016 15.2 0.1 0.066 13.2 0.0 2.1 2 0 0 2 2 2 0 Ferlin C-terminus Insulin_TMD PF17870.1 XP_667415.1 - 0.14 12.2 1.9 0.49 10.5 1.9 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 XP_667416.1 - 3.8e-46 157.6 0.0 7.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667416.1 - 5.5e-31 107.8 0.0 1.2e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 XP_667416.1 - 0.00049 20.1 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 XP_667416.1 - 0.27 10.0 0.0 0.27 10.0 0.0 2.0 2 1 0 2 2 2 0 Fungal protein kinase Calpain_III PF01067.22 XP_667416.1 - 0.79 10.0 5.7 0.16 12.2 1.9 1.8 2 0 0 2 2 2 0 Calpain large subunit, domain III AA_kinase PF00696.28 XP_667417.1 - 4.2e-38 131.3 0.4 6e-38 130.8 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 XP_667417.1 - 1e-07 31.8 1.7 1.2e-07 31.5 0.5 1.8 2 0 0 2 2 2 1 PUA domain Cyclin PF08613.11 XP_667418.1 - 3.9e-27 95.6 0.4 7e-27 94.8 0.4 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 XP_667418.1 - 0.004 16.9 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain RuvC_1 PF18516.1 XP_667418.1 - 0.02 14.1 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 RuvC nuclease domain RsbU_N PF08673.10 XP_667418.1 - 0.024 14.7 0.0 17 5.6 0.0 3.2 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain PP2C PF00481.21 XP_667419.1 - 2e-13 50.6 0.0 4.4e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DnaJ PF00226.31 XP_667421.1 - 8.7e-20 70.6 2.2 8.7e-20 70.6 2.2 2.5 2 1 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 XP_667421.1 - 5.6e-09 36.1 6.4 4.8e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_667421.1 - 9.5e-05 22.6 9.8 0.043 14.1 0.3 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain EMC3_TMCO1 PF01956.16 XP_667421.1 - 1.2 8.8 13.0 0.13 12.0 2.5 3.0 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like PA26 PF04636.13 XP_667423.1 - 4.5e-30 105.0 0.3 3.8e-22 78.8 0.0 2.3 2 0 0 2 2 2 2 PA26 p53-induced protein (sestrin) FDX-ACB PF03147.14 XP_667424.1 - 0.087 13.2 0.3 0.84 10.1 0.2 2.5 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain TcdB_N PF12918.7 XP_667424.1 - 6.6 7.1 13.3 8.7 6.7 1.2 4.2 3 1 1 4 4 4 0 TcdB toxin N-terminal helical domain Mog1 PF04603.12 XP_667425.1 - 1.3 9.4 6.6 0.85 10.0 4.1 2.2 1 1 0 1 1 1 0 Ran-interacting Mog1 protein Glycos_transf_4 PF00953.21 XP_667426.1 - 1e-35 123.0 13.2 1e-35 123.0 13.2 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 Thioredoxin PF00085.20 XP_667427.1 - 5.2e-12 45.7 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin CDC45 PF02724.14 XP_667427.1 - 4.4e-05 22.0 31.1 6.1e-05 21.5 31.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Neur_chan_memb PF02932.16 XP_667427.1 - 0.00026 21.2 5.0 0.00026 21.2 5.0 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region BUD22 PF09073.10 XP_667427.1 - 0.00028 20.4 33.6 0.00048 19.6 33.6 1.4 1 0 0 1 1 1 1 BUD22 PA26 PF04636.13 XP_667427.1 - 0.0036 16.3 11.9 0.0064 15.5 11.9 1.4 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CCSAP PF15748.5 XP_667427.1 - 0.0036 17.5 28.3 0.0036 17.5 28.3 1.8 2 0 0 2 2 2 1 Centriole, cilia and spindle-associated HyaE PF07449.11 XP_667427.1 - 0.026 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 XP_667427.1 - 0.028 13.8 0.6 0.068 12.5 0.6 1.7 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 XP_667427.1 - 0.037 14.5 0.0 0.13 12.7 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain SAPS PF04499.15 XP_667427.1 - 0.09 11.5 17.5 0.15 10.9 17.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zn_peptidase PF04228.13 XP_667427.1 - 0.11 11.9 0.3 0.99 8.8 0.1 2.4 2 1 0 2 2 2 0 Putative neutral zinc metallopeptidase Nop14 PF04147.12 XP_667427.1 - 0.27 9.4 54.6 0.41 8.8 54.6 1.2 1 0 0 1 1 1 0 Nop14-like family XRN_M PF17846.1 XP_667427.1 - 0.44 9.4 15.2 0.71 8.7 15.2 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Mpp10 PF04006.12 XP_667427.1 - 0.91 7.9 56.5 0.1 11.0 52.3 1.5 2 0 0 2 2 2 0 Mpp10 protein Spore_coat_CotO PF14153.6 XP_667427.1 - 1.4 8.8 36.2 0.055 13.4 29.6 2.0 2 0 0 2 2 2 0 Spore coat protein CotO CobT PF06213.12 XP_667427.1 - 1.6 8.1 48.0 2.7 7.3 48.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 XP_667427.1 - 2.9 7.2 57.8 4.9 6.5 57.8 1.3 1 0 0 1 1 1 0 SDA1 SLC12 PF03522.15 XP_667427.1 - 3.2 6.7 19.4 0.46 9.5 15.4 1.6 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 XP_667427.1 - 8.4 5.0 30.5 0.084 11.6 22.7 1.7 2 0 0 2 2 2 0 Presenilin Nop53 PF07767.11 XP_667427.1 - 9 5.6 52.8 16 4.8 52.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ALMT PF11744.8 XP_667427.1 - 9.2 5.0 14.6 1.1 8.0 10.4 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter LSM PF01423.22 XP_667428.1 - 6.2e-18 64.3 2.7 7.9e-18 63.9 2.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 XP_667428.1 - 0.0043 17.2 0.1 0.0058 16.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RBP_receptor PF14752.6 XP_667428.1 - 0.054 12.1 0.1 0.064 11.8 0.1 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor Ribosomal_S13_N PF08069.12 XP_667429.1 - 9.1e-28 96.1 0.2 1.7e-27 95.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 XP_667429.1 - 9.1e-14 51.4 0.9 1.2e-13 51.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 IMS_C PF11799.8 XP_667429.1 - 0.049 14.3 0.2 0.1 13.3 0.2 1.7 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain RRM_1 PF00076.22 XP_667430.1 - 3.8e-30 103.5 0.2 6.1e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 XP_667430.1 - 0.0012 19.1 0.0 0.89 9.8 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 XP_667430.1 - 0.033 14.3 0.5 13 5.9 0.1 3.5 2 2 0 2 2 2 0 RNA recognition motif DUF4523 PF15023.6 XP_667430.1 - 0.055 13.3 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Endonuclease_NS PF01223.23 XP_667431.1 - 7.7e-39 133.8 0.0 1.2e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease YfcL PF08891.11 XP_667431.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 YfcL protein HALZ PF02183.18 XP_667432.1 - 0.06 13.6 4.5 0.14 12.4 4.4 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4047 PF13256.6 XP_667432.1 - 0.85 9.8 5.9 0.24 11.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) WASH-7_N PF14745.6 XP_667433.1 - 0.022 13.3 0.7 0.032 12.7 0.7 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Zip PF02535.22 XP_667434.1 - 5.6e-37 127.7 12.0 6.7e-37 127.5 12.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DnaJ_C PF01556.18 XP_667435.1 - 1.9e-41 141.6 0.4 2.4e-41 141.3 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 XP_667435.1 - 6.3e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2784 PF10861.8 XP_667435.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Inositol_P PF00459.25 XP_667436.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family Inositol_P PF00459.25 XP_667437.1 - 3.2e-07 30.1 0.1 3.5e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 XP_667438.1 - 4.1e-53 180.4 1.4 3.5e-30 105.3 1.6 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667438.1 - 2.5e-24 86.0 0.1 6.9e-16 58.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 XP_667438.1 - 2.8e-08 34.0 0.1 0.00013 22.0 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 XP_667438.1 - 1.5e-06 27.8 0.2 0.00058 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 XP_667438.1 - 0.00037 19.9 0.1 0.00067 19.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 XP_667438.1 - 0.00098 18.2 0.1 0.0016 17.4 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain PIP49_C PF12260.8 XP_667438.1 - 0.011 15.4 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 XP_667438.1 - 0.02 13.7 0.1 0.029 13.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase TPR_1 PF00515.28 XP_667441.1 - 1.3e-43 145.0 27.6 2.2e-09 36.7 1.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 XP_667441.1 - 2.5e-36 120.9 21.6 1.3e-06 28.1 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 XP_667441.1 - 1.8e-23 81.9 10.9 1.7e-10 40.4 0.1 4.8 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 XP_667441.1 - 2.7e-19 67.7 24.7 7.2e-05 22.7 1.5 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 XP_667441.1 - 5.7e-19 68.2 1.9 3e-08 33.8 0.0 5.1 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 XP_667441.1 - 4e-17 61.3 12.4 0.00054 20.2 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 XP_667441.1 - 3e-16 59.7 4.4 0.0019 18.7 0.2 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat STI1 PF17830.1 XP_667441.1 - 1.3e-15 57.1 2.7 1.5e-15 56.8 0.6 2.4 2 0 0 2 2 1 1 STI1 domain TPR_16 PF13432.6 XP_667441.1 - 1.4e-14 54.4 0.0 8.5e-08 32.7 0.0 4.0 4 1 1 5 5 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667441.1 - 9.3e-11 41.6 0.7 3.2 8.8 0.0 6.8 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 XP_667441.1 - 4.1e-10 39.2 5.5 1.5 8.8 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 XP_667441.1 - 7.9e-10 38.7 0.2 0.0043 17.2 0.1 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 XP_667441.1 - 1.1e-05 25.1 8.3 0.0037 17.2 0.1 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_667441.1 - 1.7e-05 24.9 10.3 0.044 14.0 1.1 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 XP_667441.1 - 8e-05 23.0 11.5 0.34 11.6 0.2 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 XP_667441.1 - 0.0003 20.8 17.3 0.2 11.7 0.3 6.2 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 XP_667441.1 - 0.001 18.3 0.5 3.3 6.9 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 XP_667441.1 - 0.0021 17.8 9.6 0.033 13.9 3.5 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat-like domain XPC-binding PF09280.11 XP_667441.1 - 0.0097 15.6 1.6 0.025 14.3 1.6 1.7 1 0 0 1 1 1 1 XPC-binding domain IFNGR1 PF07140.11 XP_667441.1 - 0.037 14.1 0.7 0.079 13.1 0.7 1.6 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) Mad3_BUB1_I PF08311.12 XP_667441.1 - 0.04 13.9 8.3 0.32 11.0 0.5 3.4 3 2 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_3 PF07720.12 XP_667441.1 - 0.041 13.9 0.1 0.041 13.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 XP_667441.1 - 0.051 13.0 9.2 5.5 6.3 0.0 4.2 1 1 3 4 4 4 0 Coatomer epsilon subunit PPR PF01535.20 XP_667441.1 - 0.12 12.7 0.4 0.12 12.7 0.4 3.0 3 0 0 3 3 2 0 PPR repeat SNAP PF14938.6 XP_667441.1 - 0.29 10.5 15.0 0.11 11.9 9.4 2.4 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP Syntaxin-6_N PF09177.11 XP_667441.1 - 0.32 11.6 2.6 0.48 11.0 0.7 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MIT PF04212.18 XP_667441.1 - 0.47 10.6 16.1 12 6.1 0.1 5.7 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain RabGAP-TBC PF00566.18 XP_667442.1 - 3.3e-11 43.3 4.3 3.3e-11 43.3 4.3 4.4 5 0 0 5 5 5 2 Rab-GTPase-TBC domain WD40 PF00400.32 XP_667443.1 - 5.4e-49 163.1 32.1 3.7e-09 37.1 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667443.1 - 1e-10 41.8 2.3 0.063 13.6 0.1 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_667443.1 - 9e-06 25.2 0.0 0.18 11.1 0.0 3.1 2 2 1 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 XP_667443.1 - 0.00015 20.8 0.2 2.2 7.1 0.1 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 XP_667443.1 - 0.0033 17.9 1.0 2.2 8.9 0.0 3.9 3 1 0 3 3 3 1 PQQ-like domain VID27 PF08553.10 XP_667443.1 - 0.032 13.3 0.0 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 XP_667443.1 - 0.046 12.6 1.6 1.5 7.7 0.0 3.1 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 XP_667443.1 - 0.17 11.9 0.1 9.1 6.4 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 XP_667444.1 - 7.1e-12 45.2 0.0 7.7e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667444.1 - 9e-07 28.4 0.0 1e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 XP_667444.1 - 0.0037 16.6 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 XP_667444.1 - 0.05 12.9 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 XP_667444.1 - 0.059 12.3 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 XP_667444.1 - 0.069 11.9 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 XP_667444.1 - 0.14 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spc7 PF08317.11 XP_667445.1 - 0.00028 19.9 16.2 0.00028 19.9 16.2 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Tex_YqgF PF16921.5 XP_667445.1 - 0.044 14.2 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 Tex protein YqgF-like domain SLATT_1 PF18181.1 XP_667445.1 - 0.14 12.1 0.5 0.29 11.1 0.5 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 COG2 PF06148.11 XP_667445.1 - 0.63 10.1 10.5 0.036 14.2 2.3 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 XP_667445.1 - 0.76 9.8 10.1 0.27 11.3 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FliJ PF02050.16 XP_667445.1 - 1.2 9.4 12.9 1.4 9.1 1.7 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein DASH_Dam1 PF08653.10 XP_667445.1 - 2 8.3 4.0 42 4.1 0.1 3.1 2 1 0 2 2 2 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 XP_667445.1 - 2.7 8.1 18.5 4.4 7.4 9.8 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein BPL_N PF09825.9 XP_667445.1 - 3.7 6.5 8.7 5.1 6.1 8.7 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal YabA PF06156.13 XP_667445.1 - 8 7.2 19.2 0.54 10.9 0.5 3.3 1 1 3 4 4 4 0 Initiation control protein YabA Uso1_p115_C PF04871.13 XP_667445.1 - 9.4 6.6 21.3 1.1 9.6 14.6 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GDP_Man_Dehyd PF16363.5 XP_667446.1 - 1.1e-51 176.2 0.0 1.3e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 XP_667446.1 - 5e-45 153.8 0.0 6.4e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 XP_667446.1 - 5.1e-10 39.0 0.0 6.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 XP_667446.1 - 7.5e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 XP_667446.1 - 1.4e-05 24.3 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 XP_667446.1 - 0.0026 17.0 0.1 0.046 12.8 0.1 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 XP_667446.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 XP_667446.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 XP_667446.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding MORN PF02493.20 XP_667447.1 - 1.6e-43 144.1 74.0 1.4e-07 30.9 1.8 10.3 10 0 0 10 10 10 9 MORN repeat GrpE PF01025.19 XP_667447.1 - 0.56 9.8 10.1 0.27 10.9 6.2 2.1 2 0 0 2 2 2 0 GrpE Methyltransf_10 PF05971.12 XP_667450.1 - 2.5e-57 194.5 5.8 3.6e-36 125.0 0.6 2.8 2 1 0 2 2 2 2 RNA methyltransferase BT1 PF03092.16 XP_667451.1 - 4.4e-37 127.5 9.4 5.4e-37 127.2 9.4 1.2 1 0 0 1 1 1 1 BT1 family STT3 PF02516.14 XP_667452.1 - 2.7e-83 280.5 43.7 5.5e-83 279.5 43.7 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit NaeI PF09126.10 XP_667452.1 - 0.25 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI AMPK1_CBM PF16561.5 XP_667453.1 - 1.6e-23 82.7 0.6 6.7e-23 80.7 0.1 2.0 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Not1 PF04054.15 XP_667454.1 - 2.4e-108 362.4 1.7 2.4e-108 362.4 1.7 3.1 2 1 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 XP_667454.1 - 3.6e-53 180.3 2.3 3.3e-36 124.8 0.0 2.7 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 XP_667454.1 - 1.5e-48 164.5 0.1 4.6e-48 162.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 XP_667454.1 - 2.5e-28 98.5 0.4 8e-28 96.9 0.4 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Adaptin_N PF01602.20 XP_667455.1 - 2.2e-20 72.7 15.7 4.7e-13 48.5 0.1 5.1 4 1 0 5 5 5 4 Adaptin N terminal region Cbl_N PF02262.16 XP_667455.1 - 0.17 11.9 1.5 1.7 8.7 0.0 3.4 3 2 2 5 5 5 0 CBL proto-oncogene N-terminal domain 1 NS3_envE PF02723.14 XP_667456.1 - 1.8 8.7 7.9 2.8 8.1 1.4 2.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E EF-hand_7 PF13499.6 XP_667457.1 - 1.2e-14 54.5 0.1 3.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_667457.1 - 4.4e-14 50.9 0.4 1.5e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 XP_667457.1 - 8.5e-13 47.1 0.3 6.1e-05 22.6 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 XP_667457.1 - 1.6e-10 40.0 0.5 0.00068 19.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 XP_667457.1 - 1.4e-06 28.0 2.3 0.088 12.7 0.3 3.9 3 2 2 5 5 5 2 EF-hand domain pair Caleosin PF05042.13 XP_667457.1 - 0.00011 22.1 0.0 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 Caleosin related protein EF-hand_14 PF17959.1 XP_667457.1 - 0.057 13.8 0.0 0.19 12.1 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 XP_667457.1 - 0.11 12.7 0.1 15 5.9 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain DUF751 PF05421.11 XP_667458.1 - 0.016 15.9 3.5 2.4 9.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF751) ING PF12998.7 XP_667459.1 - 6.7e-13 49.1 4.2 6.7e-13 49.1 4.2 2.3 2 1 1 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 XP_667459.1 - 1.3 9.0 15.9 0.54 10.2 12.4 2.2 2 1 0 2 2 2 0 PHD-finger CBFD_NFYB_HMF PF00808.23 XP_667460.1 - 0.00029 21.0 3.2 0.00075 19.7 3.2 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FHA_2 PF17913.1 XP_667460.1 - 0.0033 17.6 0.8 0.0047 17.1 0.8 1.2 1 0 0 1 1 1 1 FHA domain EMC3_TMCO1 PF01956.16 XP_667460.1 - 0.049 13.4 1.1 0.063 13.0 1.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4467 PF14729.6 XP_667460.1 - 0.059 13.7 0.7 0.059 13.7 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) DUF5394 PF17372.2 XP_667460.1 - 0.66 9.5 8.6 0.85 9.1 8.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5394) Pro_isomerase PF00160.21 XP_667461.1 - 7.7e-45 153.0 0.0 8.8e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDOST_48kD PF03345.14 XP_667462.1 - 1.2e-91 307.6 4.4 1.6e-91 307.2 4.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Metallophos PF00149.28 XP_667463.1 - 6.5e-18 66.0 0.6 1.4e-17 64.8 0.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 XP_667463.1 - 9.7e-12 43.6 0.7 0.00065 19.1 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 XP_667463.1 - 5.2e-11 42.8 0.5 0.00019 21.8 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_667463.1 - 3.7e-10 38.9 0.3 0.0026 17.5 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 XP_667463.1 - 1.4e-05 24.9 0.1 0.054 13.3 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 XP_667463.1 - 0.0023 17.3 0.1 3.4 7.3 0.0 3.1 3 0 0 3 3 3 2 EF hand Pkinase PF00069.25 XP_667466.1 - 4.3e-47 160.7 0.0 4.3e-46 157.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667466.1 - 2.2e-18 66.5 0.0 1.3e-10 41.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_667466.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 XP_667466.1 - 0.00053 19.4 0.1 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.23 XP_667467.1 - 3.7e-86 287.8 0.0 6.1e-86 287.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 XP_667467.1 - 2.4e-28 98.5 0.8 5.8e-28 97.3 0.8 1.7 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 XP_667467.1 - 1.5e-19 70.2 1.8 1.6e-18 66.9 0.1 2.9 3 0 0 3 3 2 1 MCM AAA-lid domain MCM_N PF14551.6 XP_667467.1 - 7.7e-08 32.9 0.0 2.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 XP_667467.1 - 2.9e-07 30.1 0.1 8e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_667467.1 - 0.017 15.0 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF5137 PF17220.3 XP_667467.1 - 0.021 15.7 1.3 0.068 14.1 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) Sigma54_activat PF00158.26 XP_667467.1 - 0.023 14.4 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 XP_667467.1 - 0.025 15.0 0.0 0.098 13.1 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 XP_667467.1 - 0.026 14.5 0.0 0.18 11.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RcpC PF16976.5 XP_667467.1 - 0.041 13.9 0.7 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB AAA_16 PF13191.6 XP_667467.1 - 0.16 12.4 0.6 1.1 9.7 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 XP_667467.1 - 0.18 12.1 0.4 8.2 6.7 0.0 3.1 3 1 1 4 4 4 0 AAA domain EGF_CA PF07645.15 XP_667468.1 - 5.3e-24 84.1 72.1 9.6e-12 44.9 4.5 7.2 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 XP_667468.1 - 5.2e-17 61.4 40.5 4.5e-08 32.9 0.9 7.3 7 0 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 XP_667468.1 - 6.2e-06 26.4 69.5 0.00012 22.3 9.8 7.5 7 1 1 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 XP_667468.1 - 0.00019 21.5 14.3 0.00074 19.7 3.4 7.0 6 1 1 7 7 7 4 EGF domain EGF PF00008.27 XP_667468.1 - 0.00099 19.4 14.5 0.004 17.4 7.4 7.5 7 1 0 7 7 7 4 EGF-like domain hEGF PF12661.7 XP_667468.1 - 0.0016 19.0 57.2 0.0021 18.7 1.8 7.9 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 XP_667468.1 - 0.017 15.2 2.2 0.017 15.2 2.2 6.7 5 1 1 6 6 6 0 MSP1 EGF domain 1 zf-Mss51 PF13824.6 XP_667469.1 - 0.05 13.7 0.3 15 5.8 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-B_box PF00643.24 XP_667469.1 - 0.3 11.3 3.5 6.2 7.1 0.8 2.5 2 0 0 2 2 2 0 B-box zinc finger Vps26 PF03643.15 XP_667470.1 - 6.6e-51 172.9 0.6 7.5e-51 172.7 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DNA_mis_repair PF01119.19 XP_667471.1 - 1.6e-18 66.5 0.7 3.6e-18 65.4 0.2 1.9 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 XP_667471.1 - 2e-13 50.4 0.7 5.6e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 XP_667471.1 - 5.4e-06 26.9 1.0 1.6e-05 25.4 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ubiquitin PF00240.23 XP_667472.1 - 2.8e-105 344.2 10.1 2.7e-34 116.7 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 XP_667472.1 - 4.3e-51 170.6 10.7 2.9e-16 59.1 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 XP_667472.1 - 2.3e-20 72.8 3.3 7e-05 23.2 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 XP_667472.1 - 1.2e-12 47.6 1.7 0.014 15.3 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 XP_667472.1 - 7.2e-12 45.4 1.0 0.043 13.9 0.0 4.0 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 XP_667472.1 - 1.1e-11 44.9 2.5 0.029 14.7 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 XP_667472.1 - 2.9e-09 37.4 0.1 0.38 11.4 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 XP_667472.1 - 1.3e-06 28.3 0.0 1.6 8.6 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 XP_667472.1 - 4.2e-06 26.7 14.1 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 XP_667472.1 - 0.00024 21.4 0.1 20 5.6 0.0 3.8 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 XP_667472.1 - 0.0007 19.0 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase RBD PF02196.15 XP_667472.1 - 0.00076 19.5 0.0 22 5.2 0.0 3.4 3 0 0 3 3 3 0 Raf-like Ras-binding domain UDP-g_GGTase PF06427.11 XP_667472.1 - 0.0018 18.3 2.0 3.4 7.8 0.0 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF3861 PF12977.7 XP_667472.1 - 0.0019 18.3 0.4 27 5.0 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 XP_667472.1 - 0.0065 15.9 0.0 14 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) FlgD_ig PF13860.6 XP_667472.1 - 0.019 14.8 2.4 39 4.2 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Big_7 PF17957.1 XP_667472.1 - 0.02 15.6 0.0 90 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain GDYXXLXY PF14345.6 XP_667472.1 - 0.053 13.3 0.1 75 3.1 0.0 3.3 3 0 0 3 3 3 0 GDYXXLXY protein CorA PF01544.18 XP_667472.1 - 0.059 12.7 0.1 51 3.0 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Phage_sheath_1N PF17481.2 XP_667472.1 - 0.059 13.9 1.4 22 5.6 1.4 3.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain ORF11CD3 PF10549.9 XP_667472.1 - 0.059 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain TraK PF06586.11 XP_667472.1 - 0.069 12.8 0.1 59 3.2 0.0 3.1 3 0 0 3 3 3 0 TraK protein ProRS-C_2 PF09181.10 XP_667472.1 - 0.086 13.0 1.1 89 3.3 0.0 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DMA PF03474.14 XP_667472.1 - 0.42 10.2 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif PI3K_p85B PF02192.16 XP_667472.1 - 1.3 8.8 3.4 1.1e+02 2.6 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain WD40 PF00400.32 XP_667473.1 - 2.8e-08 34.3 22.9 0.069 14.0 0.0 9.6 11 0 0 11 11 11 2 WD domain, G-beta repeat Pox_A12 PF04651.13 XP_667473.1 - 0.047 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Poxvirus A12 protein Peptidase_S31 PF05578.12 XP_667473.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 CECR6_TMEM121 PF14997.6 XP_667474.1 - 3.2e-13 50.0 5.1 3.2e-13 50.0 5.1 2.2 2 0 0 2 2 2 1 CECR6/TMEM121 family Pkinase PF00069.25 XP_667476.1 - 5.9e-80 268.4 0.0 6.6e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667476.1 - 3.3e-35 121.6 0.0 4.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 XP_667476.1 - 7.6e-05 21.8 0.1 0.00062 18.8 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 XP_667476.1 - 0.00013 22.0 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 XP_667476.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 XP_667476.1 - 0.012 15.2 0.3 0.044 13.4 0.1 1.7 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 XP_667476.1 - 0.039 13.3 0.8 0.1 12.0 0.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 XP_667476.1 - 0.085 12.5 0.2 0.64 9.6 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 XP_667476.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 GRIP PF01465.20 XP_667477.1 - 4.1 7.4 6.3 2.5 8.1 0.7 2.7 2 0 0 2 2 2 0 GRIP domain YIF1 PF03878.15 XP_667478.1 - 1.2e-05 25.0 3.3 1.8e-05 24.4 3.3 1.2 1 0 0 1 1 1 1 YIF1 Rad60-SLD PF11976.8 XP_667479.1 - 2.8e-10 39.9 0.0 3.1e-08 33.3 0.0 3.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.7 XP_667479.1 - 0.002 18.0 1.4 0.0047 16.8 1.4 1.6 1 0 0 1 1 1 1 F-box-like ubiquitin PF00240.23 XP_667479.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family F-box PF00646.33 XP_667479.1 - 0.0082 16.0 0.2 0.027 14.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain PS_pyruv_trans PF04230.13 XP_667481.1 - 4.2e-15 56.4 6.5 4.6e-14 53.0 6.5 2.3 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 XP_667482.1 - 1.1e-08 34.8 19.3 4.1e-08 32.9 16.1 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 XP_667482.1 - 1.1e-06 28.9 0.8 1.1e-06 28.9 0.8 3.4 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 XP_667482.1 - 0.0026 17.3 12.7 0.0026 17.3 12.7 2.4 2 1 0 2 2 2 1 Solute carrier family 35 DUF4083 PF13314.6 XP_667482.1 - 0.09 12.7 0.3 0.09 12.7 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Tnp_22_dsRBD PF17490.2 XP_667483.1 - 0.085 12.9 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Kelch_1 PF01344.25 XP_667484.1 - 5.7e-29 99.4 1.2 2.1e-06 27.2 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 XP_667484.1 - 2.9e-27 94.4 4.4 7e-06 26.0 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 XP_667484.1 - 3.1e-19 68.5 12.0 3.8e-05 23.8 0.0 6.7 5 1 2 7 7 7 4 Kelch motif BTB_2 PF02214.22 XP_667484.1 - 2.9e-15 56.4 0.0 9.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 XP_667484.1 - 1.4e-11 43.9 6.2 0.014 15.3 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 XP_667484.1 - 1.5e-09 37.9 0.8 0.44 10.9 0.0 6.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 XP_667484.1 - 0.00093 19.1 7.0 4.3 7.4 0.0 4.7 6 0 0 6 6 6 3 Kelch motif zf-C4H2 PF10146.9 XP_667484.1 - 0.4 11.0 10.5 0.62 10.3 10.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 XP_667484.1 - 2 9.0 18.7 3.3 8.2 18.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PulA_N1 PF17999.1 XP_667484.1 - 7 7.5 6.6 16 6.3 2.2 2.5 2 0 0 2 2 2 0 Pullulanase N1-terminal domain AAA_lid_9 PF17871.1 XP_667485.1 - 1.6e-06 28.0 0.0 6e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA lid domain TIP49 PF06068.13 XP_667485.1 - 3.4e-05 23.2 0.0 0.00015 21.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 XP_667485.1 - 0.018 15.1 0.0 0.062 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 XP_667485.1 - 0.027 14.9 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 XP_667485.1 - 0.043 13.3 0.0 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region CbiA PF01656.23 XP_667485.1 - 0.067 13.3 0.0 0.85 9.7 0.0 2.9 3 3 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 XP_667485.1 - 0.068 12.2 0.8 8.1 5.4 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 XP_667485.1 - 0.1 12.3 0.0 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.20 XP_667485.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 XP_667485.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Patatin PF01734.22 XP_667486.1 - 1.5e-06 28.5 0.6 0.00027 21.2 0.2 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_19 PF14559.6 XP_667487.1 - 2e-11 44.2 0.0 5.1e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 XP_667487.1 - 2.6e-08 33.3 0.1 0.042 14.0 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 XP_667487.1 - 1.4e-07 31.4 0.0 0.0005 20.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 XP_667487.1 - 4.5e-07 30.4 0.0 0.0059 17.2 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667487.1 - 7.5e-06 26.3 0.0 0.056 14.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_667487.1 - 2.2e-05 24.3 2.6 0.56 10.6 0.0 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 XP_667487.1 - 0.00022 20.1 0.1 0.00041 19.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 XP_667487.1 - 0.00051 20.2 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 XP_667487.1 - 0.01 15.6 0.0 0.45 10.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 XP_667487.1 - 0.013 15.5 0.0 23 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 XP_667487.1 - 0.12 12.6 0.0 5.1 7.5 0.0 3.2 3 1 0 4 4 4 0 Tetratricopeptide repeat S-AdoMet_synt_C PF02773.16 XP_667488.1 - 6e-62 207.7 0.2 2.1e-61 206.0 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 XP_667488.1 - 1.1e-43 148.2 0.0 2e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 XP_667488.1 - 3.3e-41 140.0 1.1 5.9e-41 139.2 0.3 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 XP_667488.1 - 0.022 13.6 0.3 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Rad17 PF03215.15 XP_667489.1 - 6e-12 45.9 0.1 6e-12 45.9 0.1 3.0 2 1 0 3 3 3 1 Rad17 P-loop domain AAA_23 PF13476.6 XP_667489.1 - 3.5e-06 27.6 1.6 3.5e-06 27.6 1.6 4.1 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.27 XP_667489.1 - 0.00012 22.6 0.0 0.0004 20.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 XP_667489.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 XP_667489.1 - 0.0031 17.8 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF916 PF06030.12 XP_667489.1 - 0.014 15.5 3.7 0.023 14.7 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) AAA_19 PF13245.6 XP_667489.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 XP_667489.1 - 0.022 14.7 1.8 0.034 14.0 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 XP_667489.1 - 0.027 14.1 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 XP_667489.1 - 0.03 14.4 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 XP_667489.1 - 0.039 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 XP_667489.1 - 0.051 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 XP_667489.1 - 0.062 12.7 0.5 0.13 11.7 0.5 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 XP_667489.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 XP_667489.1 - 0.23 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 XP_667490.1 - 1.3e-41 143.4 0.5 1.6e-41 143.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 XP_667490.1 - 7.3e-23 80.8 0.3 1.8e-22 79.5 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Kinesin PF00225.23 XP_667491.1 - 2.7e-99 332.3 6.4 2.7e-99 332.3 6.4 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 XP_667491.1 - 1.6e-49 167.7 0.3 1.6e-49 167.7 0.3 2.6 2 0 0 2 2 2 1 Microtubule binding Fzo_mitofusin PF04799.13 XP_667491.1 - 0.11 12.0 5.9 0.34 10.4 5.9 1.8 1 0 0 1 1 1 0 fzo-like conserved region CREPT PF16566.5 XP_667491.1 - 0.12 12.6 14.1 0.07 13.3 10.9 2.3 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF948 PF06103.11 XP_667491.1 - 0.32 11.3 8.0 0.76 10.1 4.9 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 XP_667491.1 - 1.5 9.3 16.6 4.2 7.9 16.6 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region YvrJ PF12841.7 XP_667491.1 - 2.7 7.6 4.5 36 4.0 0.7 2.9 2 0 0 2 2 2 0 YvrJ protein family YtxH PF12732.7 XP_667491.1 - 8.6 7.0 9.1 67 4.1 7.9 3.0 2 1 0 2 2 2 0 YtxH-like protein RRM_1 PF00076.22 XP_667492.1 - 8e-18 64.0 0.2 1.8e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_667492.1 - 8.9e-06 25.3 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_667492.1 - 1.6e-05 24.6 0.0 0.00042 20.1 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif Methyltransf_16 PF10294.9 XP_667493.1 - 4.8e-11 42.7 0.1 1.5e-10 41.1 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase DUF2866 PF11065.8 XP_667493.1 - 0.00046 20.1 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2866) FAM86 PF14904.6 XP_667493.1 - 0.0012 18.8 0.1 0.0026 17.8 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function PrmA PF06325.13 XP_667493.1 - 0.058 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RabGAP-TBC PF00566.18 XP_667494.1 - 1.1e-52 178.8 2.3 1.1e-52 178.8 2.3 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AbiJ_NTD4 PF18863.1 XP_667494.1 - 0.012 16.1 0.9 0.04 14.4 0.1 2.1 2 1 0 2 2 2 0 AbiJ N-terminal domain 4 Histone PF00125.24 XP_667495.1 - 1.4e-51 174.3 1.3 1.5e-51 174.1 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 XP_667495.1 - 0.00032 21.0 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 XP_667495.1 - 0.00033 20.7 0.1 0.00054 20.1 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 XP_667495.1 - 0.00087 19.9 2.9 0.0011 19.6 2.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 XP_667495.1 - 0.012 15.9 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 XP_667495.1 - 0.034 14.2 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Proteasome PF00227.26 XP_667496.1 - 8.3e-50 168.9 0.2 1e-49 168.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_2 PF07719.17 XP_667497.1 - 5.5e-10 38.6 0.3 0.055 13.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_667497.1 - 6.4e-08 32.1 4.9 0.37 10.7 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 XP_667497.1 - 2.2e-06 27.7 0.3 0.0034 17.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 XP_667497.1 - 0.0017 18.9 0.0 0.097 13.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 XP_667497.1 - 0.0026 18.2 0.0 0.36 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_667497.1 - 0.014 15.6 3.7 1.9 8.8 0.2 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 XP_667497.1 - 0.047 13.9 10.4 91 3.7 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 XP_667497.1 - 0.079 12.7 0.5 8.7 6.1 0.0 2.9 2 0 0 2 2 2 0 TPR repeat DUF1965 PF09248.10 XP_667497.1 - 0.11 12.3 1.3 0.23 11.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Fis1_TPR_C PF14853.6 XP_667497.1 - 0.25 11.5 1.3 2.3 8.4 0.0 3.1 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Myb_DNA-binding PF00249.31 XP_667498.1 - 2.7e-11 43.5 4.6 9.2e-11 41.8 1.4 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_667498.1 - 1e-09 38.5 0.5 1e-09 38.5 0.5 3.8 5 0 0 5 5 5 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 XP_667498.1 - 0.099 12.8 1.0 0.6 10.3 0.2 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1a PF18602.1 XP_667498.1 - 0.12 12.7 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Rap1a immunity proteins Myb_DNA-bind_5 PF13873.6 XP_667498.1 - 0.7 10.0 6.6 12 6.1 0.3 4.0 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain Nup35_RRM_2 PF14605.6 XP_667499.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_31 PF01055.26 XP_667499.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 31 Thioredoxin PF00085.20 XP_667500.1 - 3.8e-09 36.5 0.0 1.1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin DUF4284 PF14112.6 XP_667500.1 - 0.054 14.4 1.0 0.054 14.4 1.0 3.0 4 0 0 4 4 4 0 Immunity protein 22 DASH_Duo1 PF08651.10 XP_667502.1 - 2.8 7.8 8.2 0.4 10.5 0.2 3.3 4 0 0 4 4 4 0 DASH complex subunit Duo1 eIF3_subunit PF08597.10 XP_667503.1 - 1.9e-08 34.5 6.4 3.9e-08 33.5 6.4 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit UbiA PF01040.18 XP_667504.1 - 1.8e-06 27.5 0.1 2.3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GYF PF02213.16 XP_667505.1 - 2e-08 33.7 0.1 6.6e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 GYF domain IQ PF00612.27 XP_667505.1 - 0.013 15.2 1.4 0.033 14.0 1.4 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_S13 PF00416.22 XP_667506.1 - 6.1e-53 178.6 3.8 7.1e-53 178.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 UBA_4 PF14555.6 XP_667509.1 - 9.9e-14 50.9 0.6 2e-13 49.9 0.6 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 XP_667509.1 - 3.3e-06 27.2 0.0 8.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 XP_667509.1 - 0.0064 16.1 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 TAP C-terminal domain Ubiquitin_3 PF14836.6 XP_667509.1 - 0.011 15.7 0.5 1.4 8.9 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-like domain Coiled-coil_56 PF09813.9 XP_667509.1 - 6.9 6.8 10.0 1.2 9.2 3.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Ribosomal_L11_N PF03946.14 XP_667510.1 - 1.2e-20 73.0 0.2 2.5e-20 72.0 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 XP_667510.1 - 4e-14 52.9 0.4 6.5e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ZYG-11_interact PF05884.12 XP_667510.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 14-3-3 PF00244.20 XP_667511.1 - 3.1e-98 327.7 5.5 3.5e-98 327.5 5.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 XP_667511.1 - 0.0031 17.8 1.4 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667511.1 - 0.031 15.1 3.1 10 7.2 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Orbi_VP5 PF00901.17 XP_667511.1 - 0.041 12.3 1.9 0.6 8.4 2.1 2.2 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Adaptin_binding PF10199.9 XP_667511.1 - 0.12 12.9 0.8 0.84 10.2 0.7 2.1 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 YkyA PF10368.9 XP_667511.1 - 0.74 9.5 7.9 6 6.5 0.2 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CREPT PF16566.5 XP_667511.1 - 7 6.8 7.8 7.2 6.8 0.1 2.5 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour EF-hand_7 PF13499.6 XP_667513.1 - 1.7e-23 82.8 8.4 4.3e-13 49.5 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_667513.1 - 3.6e-22 76.2 16.0 7.8e-09 34.5 1.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 XP_667513.1 - 3.2e-19 67.2 8.5 3.8e-05 23.3 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 XP_667513.1 - 4.1e-17 61.8 9.2 9e-14 51.1 0.7 4.0 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 XP_667513.1 - 1.1e-11 44.8 0.1 7.9e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 XP_667513.1 - 8e-06 25.8 2.5 0.044 13.7 0.8 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 XP_667513.1 - 3.1e-05 23.3 14.8 0.00091 18.6 1.4 4.6 5 1 0 5 5 5 2 EF hand SurA_N_2 PF13623.6 XP_667513.1 - 0.048 13.5 0.7 0.48 10.3 0.1 2.3 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 XP_667513.1 - 0.06 13.7 1.0 1.2 9.5 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 XP_667513.1 - 0.06 13.1 1.8 0.17 11.7 0.5 1.9 1 1 1 2 2 2 0 SurA N-terminal domain B5 PF03484.15 XP_667513.1 - 0.088 13.1 1.3 18 5.7 0.0 3.0 2 2 0 2 2 2 0 tRNA synthetase B5 domain DUF2767 PF10965.8 XP_667513.1 - 0.089 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Toprim_2 PF13155.6 XP_667513.1 - 0.089 13.2 0.4 0.68 10.4 0.1 2.3 1 1 2 3 3 3 0 Toprim-like MgtE_N PF03448.17 XP_667513.1 - 0.13 12.9 1.4 0.18 12.5 0.4 1.8 2 0 0 2 2 1 0 MgtE intracellular N domain SUB1_ProdP9 PF18213.1 XP_667513.1 - 0.17 11.7 2.4 1.2 9.0 0.5 2.4 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 SPARC_Ca_bdg PF10591.9 XP_667513.1 - 0.27 11.5 1.1 0.5 10.7 0.5 1.8 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HTH_40 PF14493.6 XP_667513.1 - 0.39 11.2 3.1 1.2 9.7 0.5 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain zf-C3HC4_3 PF13920.6 XP_667514.1 - 2.2e-14 53.0 10.8 4.4e-14 52.1 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 XP_667514.1 - 3.5e-07 30.0 11.3 7.8e-07 28.9 11.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 XP_667514.1 - 3.8e-06 27.1 14.6 6.5e-06 26.4 13.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 XP_667514.1 - 0.0011 18.9 12.3 0.0035 17.3 12.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Spindle_Spc25 PF08234.12 XP_667514.1 - 0.0094 16.1 0.8 0.027 14.7 0.3 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 zf-C3HC4_2 PF13923.6 XP_667514.1 - 0.22 11.4 15.0 0.18 11.7 13.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 XP_667514.1 - 0.78 9.5 12.5 2.9 7.6 12.5 1.9 1 1 0 1 1 1 0 P-11 zinc finger DUF916 PF06030.12 XP_667514.1 - 1.1 9.4 5.7 1.6 8.8 2.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Ribosomal_L14e PF01929.17 XP_667515.1 - 8.4e-14 51.8 0.1 1.1e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 XP_667515.1 - 0.095 12.7 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 KOW motif WhiA_N PF10298.9 XP_667516.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain DUF3744 PF12558.8 XP_667516.1 - 0.096 13.5 0.0 0.61 10.9 0.0 2.2 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter zf-CCCH_2 PF14608.6 XP_667517.1 - 2.2e-14 53.3 30.5 3.9e-05 24.0 2.1 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger PWI PF01480.17 XP_667517.1 - 2.5e-06 27.7 0.1 4.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 PWI domain zf-CCCH_4 PF18044.1 XP_667517.1 - 0.37 10.7 24.0 0.092 12.6 1.4 4.1 3 1 0 3 3 3 0 CCCH-type zinc finger HABP4_PAI-RBP1 PF04774.15 XP_667518.1 - 0.00024 21.9 9.3 0.00024 21.9 9.3 2.9 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family DUF21 PF01595.20 XP_667519.1 - 7.8e-40 136.4 3.9 1.4e-39 135.6 3.9 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Prefoldin_2 PF01920.20 XP_667520.1 - 8.7e-18 64.2 8.9 1.1e-17 63.9 8.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 XP_667520.1 - 9.7e-05 22.3 4.0 0.00018 21.4 3.9 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 XP_667520.1 - 0.011 15.7 2.3 0.026 14.6 2.3 1.7 1 1 0 1 1 1 0 Prefoldin subunit COG5 PF10392.9 XP_667520.1 - 0.061 13.5 4.5 0.082 13.1 2.4 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spc24 PF08286.11 XP_667520.1 - 0.63 10.3 5.7 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fumble PF03630.14 XP_667521.1 - 1.9e-23 83.2 2.3 2.1e-23 83.0 1.5 1.3 1 1 0 1 1 1 1 Fumble Dala_Dala_lig_C PF07478.13 XP_667521.1 - 0.026 14.1 0.8 0.057 13.0 0.3 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus HIPIP PF01355.17 XP_667523.1 - 0.4 11.1 1.4 0.46 10.9 0.3 1.6 2 0 0 2 2 2 0 High potential iron-sulfur protein MOZ_SAS PF01853.18 XP_667524.1 - 4.8e-67 225.1 0.7 7.8e-64 214.6 0.7 2.3 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 XP_667524.1 - 1.3e-21 75.9 1.9 2.9e-21 74.8 1.9 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 XP_667524.1 - 5.7e-10 38.9 0.7 1.2e-09 37.9 0.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 XP_667524.1 - 0.00017 22.0 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 XP_667524.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 XP_667524.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MadL PF03817.13 XP_667525.1 - 0.015 15.3 0.4 0.074 13.1 0.0 2.1 2 0 0 2 2 2 0 Malonate transporter MadL subunit FKS1_dom1 PF14288.6 XP_667525.1 - 0.093 13.1 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3067 PF11267.8 XP_667525.1 - 0.19 12.3 0.0 0.35 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) DUF2318 PF10080.9 XP_667526.1 - 0.0013 18.9 0.5 0.0025 17.9 0.5 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) EXOSC1 PF10447.9 XP_667526.1 - 0.059 14.0 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Zn_Tnp_IS91 PF14319.6 XP_667526.1 - 0.14 12.2 1.6 0.23 11.5 0.7 1.8 2 0 0 2 2 2 0 Transposase zinc-binding domain UQ_con PF00179.26 XP_667527.1 - 5.9e-30 103.8 0.1 6.9e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 XP_667527.1 - 0.0056 16.9 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain EF-hand_6 PF13405.6 XP_667528.1 - 0.15 12.1 0.0 0.52 10.4 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain DEAD PF00270.29 XP_667529.1 - 4.4e-36 124.3 0.0 1.7e-35 122.3 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667529.1 - 4.6e-26 91.3 0.0 2.7e-25 88.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 XP_667529.1 - 0.0028 18.0 0.7 0.023 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain ERCC3_RAD25_C PF16203.5 XP_667529.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.9 3 1 1 4 4 4 0 ERCC3/RAD25/XPB C-terminal helicase Porin_OmpL1 PF11389.8 XP_667529.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 DUF1084 PF06454.11 XP_667531.1 - 4.5e-14 52.5 18.8 4.5e-14 52.5 18.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) RRM_1 PF00076.22 XP_667532.1 - 6.2e-15 54.8 0.0 4.4e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromo_TP PF07524.13 XP_667533.1 - 0.00057 19.8 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 XP_667533.1 - 0.95 10.1 2.9 1.9 9.1 2.9 1.5 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term ThiF PF00899.21 XP_667534.1 - 6.1e-62 209.1 0.1 9.1e-62 208.6 0.1 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 XP_667534.1 - 5e-14 52.6 0.0 2.8e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 XP_667534.1 - 1.1e-08 35.3 3.5 5.8e-07 29.7 1.8 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 XP_667534.1 - 0.00059 20.2 0.7 0.0022 18.4 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 XP_667534.1 - 0.0056 16.9 4.2 0.034 14.4 2.1 2.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 XP_667534.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 XP_667534.1 - 0.047 14.3 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 XP_667535.1 - 1.3e-21 76.9 30.6 1.3e-21 76.9 30.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 XP_667535.1 - 1.7e-17 63.0 28.8 8.6e-13 47.4 2.7 3.1 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 XP_667535.1 - 7.3e-09 35.0 12.9 7.3e-09 35.0 12.9 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 XP_667535.1 - 0.0065 15.8 7.1 0.014 14.7 2.7 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Proteasome PF00227.26 XP_667536.1 - 3.6e-56 189.7 0.0 4.6e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 XP_667536.1 - 2.9e-14 52.4 0.0 4.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FAM83 PF07894.12 XP_667536.1 - 0.085 12.4 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 FAM83 A-H Dynactin_p62 PF05502.13 XP_667537.1 - 3e-20 72.5 20.2 1.7e-15 56.8 11.9 2.2 1 1 0 2 2 2 2 Dynactin p62 family zf_UBZ PF18439.1 XP_667537.1 - 0.088 12.4 14.3 2.5 7.8 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 XP_667537.1 - 0.24 11.4 18.1 4.2 7.5 10.8 3.6 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 XP_667537.1 - 0.93 9.5 18.1 0.48 10.4 0.5 4.0 3 1 1 4 4 4 0 zinc-ribbons DnaJ PF00226.31 XP_667539.1 - 5.5e-06 26.4 3.8 8.6e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain DUF953 PF06110.11 XP_667539.1 - 0.035 13.7 0.1 0.097 12.3 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) zf-C4_ClpX PF06689.13 XP_667539.1 - 0.75 9.7 5.2 15 5.5 0.1 3.0 3 0 0 3 3 3 0 ClpX C4-type zinc finger DUF1754 PF08555.10 XP_667540.1 - 7.6 7.4 9.8 47 4.9 9.8 2.1 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF5582 PF17819.1 XP_667542.1 - 0.011 16.2 2.7 0.011 16.2 2.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5582) Moulting_cycle PF04870.16 XP_667542.1 - 0.082 12.2 7.1 0.1 11.8 7.1 1.1 1 0 0 1 1 1 0 Moulting cycle Ndc1_Nup PF09531.10 XP_667542.1 - 0.68 8.5 4.0 0.67 8.6 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 XP_667542.1 - 4.6 5.9 5.1 4.6 5.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin Laminin_G_3 PF13385.6 XP_667544.1 - 1e-06 29.0 0.4 6.1e-06 26.5 0.3 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily GP67 PF17634.2 XP_667544.1 - 1.7 9.1 8.0 1.6 9.2 4.2 2.2 2 0 0 2 2 2 0 Gene product 67 PCI PF01399.27 XP_667545.1 - 2.1e-08 34.6 7.7 2.1e-08 34.6 7.7 3.2 3 1 0 3 3 3 1 PCI domain Med9 PF07544.13 XP_667545.1 - 0.0017 18.4 1.4 2.3 8.4 0.0 3.9 3 1 1 4 4 4 2 RNA polymerase II transcription mediator complex subunit 9 CSN8_PSD8_EIF3K PF10075.9 XP_667545.1 - 0.026 14.5 0.5 0.13 12.3 0.1 2.4 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family DUF4373 PF14297.6 XP_667545.1 - 2.2 9.1 6.7 2.2 9.1 0.0 3.8 3 2 0 4 4 4 0 Domain of unknown function (DUF4373) DASH_Dad4 PF08650.10 XP_667545.1 - 7.1 6.7 13.1 12 5.9 0.3 4.4 4 0 0 4 4 4 0 DASH complex subunit Dad4 WD40 PF00400.32 XP_667546.1 - 4e-10 40.1 7.9 0.0024 18.7 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667546.1 - 0.013 15.8 0.0 0.45 10.8 0.0 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2009 PF09418.10 XP_667547.1 - 6.9e-71 239.7 6.2 3.9e-60 204.2 1.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) S_layer_N PF05123.12 XP_667547.1 - 0.035 14.0 0.2 0.035 14.0 0.2 1.8 2 0 0 2 2 2 0 S-layer like family, N-terminal region E2F_TDP PF02319.20 XP_667548.1 - 3.5e-14 52.6 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 XP_667548.1 - 0.031 14.1 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Trypan_PARP PF05887.11 XP_667549.1 - 7.5 6.5 8.5 2.9 7.9 5.6 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-CCCH PF00642.24 XP_667550.1 - 1.2e-08 34.6 2.1 1.2e-08 34.6 2.1 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 XP_667550.1 - 0.00091 19.5 8.3 0.00091 19.5 8.3 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 XP_667550.1 - 0.0026 17.6 8.4 0.0026 17.6 8.4 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 XP_667550.1 - 0.012 15.6 8.9 0.028 14.4 8.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 XP_667550.1 - 0.082 12.8 11.6 0.02 14.7 8.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 XP_667550.1 - 0.087 13.5 0.1 0.087 13.5 0.1 2.4 3 0 0 3 3 3 0 Torus domain zf-C3HC4 PF00097.25 XP_667550.1 - 4.9 7.1 9.6 15 5.5 9.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HIT PF01230.23 XP_667552.1 - 1.2e-25 90.1 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 XP_667552.1 - 1.5e-16 60.9 0.1 1.8e-16 60.6 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SHS2_Rpb7-N PF03876.17 XP_667554.1 - 8.6e-07 29.2 0.0 2.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 XP_667554.1 - 0.0052 17.4 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I PLU-1 PF08429.11 XP_667556.1 - 1.1e-20 74.1 46.4 3.1e-18 66.1 17.5 5.6 4 3 1 5 5 5 3 PLU-1-like protein Prp18 PF02840.15 XP_667556.1 - 0.42 10.6 3.9 0.52 10.4 0.7 2.8 2 0 0 2 2 2 0 Prp18 domain EF-G-binding_N PF07299.11 XP_667556.1 - 0.91 10.1 8.2 5.2 7.7 0.5 4.9 5 0 0 5 5 5 0 Elongation factor G-binding protein, N-terminal NTF2 PF02136.20 XP_667558.1 - 5.5e-11 43.1 0.4 1.6e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mucin PF01456.17 XP_667558.1 - 0.69 9.9 14.5 0.18 11.8 9.5 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein RCC1 PF00415.18 XP_667559.1 - 1.2e-110 362.0 39.1 3.2e-12 46.9 0.5 13.5 13 1 0 13 13 13 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 XP_667559.1 - 6.4e-46 153.3 77.9 1.6e-07 30.9 0.2 14.0 13 1 0 13 13 13 11 Regulator of chromosome condensation (RCC1) repeat RasGAP_C PF03836.15 XP_667559.1 - 0.22 11.7 6.7 0.028 14.6 1.7 2.1 2 0 0 2 2 2 0 RasGAP C-terminus NMT PF01233.19 XP_667560.1 - 1.1e-64 217.1 0.1 2.4e-64 216.0 0.1 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 XP_667560.1 - 1e-48 165.7 8.6 3.6e-38 131.2 6.1 2.9 2 1 1 3 3 3 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 XP_667560.1 - 0.00046 20.3 0.0 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 XP_667560.1 - 0.0031 17.7 0.0 0.0077 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 XP_667560.1 - 0.13 12.2 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 XP_667561.1 - 2.4e-34 118.5 0.1 3e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 XP_667561.1 - 1.2e-32 113.4 0.0 1.7e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 XP_667561.1 - 4.5e-08 33.2 0.1 2.1e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 XP_667561.1 - 2.1e-06 27.4 0.0 5e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 XP_667561.1 - 1.2e-05 24.5 2.5 5.9e-05 22.2 2.5 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 XP_667561.1 - 1.3e-05 24.5 1.1 5.8e-05 22.4 1.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 XP_667561.1 - 0.0026 17.0 0.2 0.7 9.0 0.2 3.0 2 1 0 2 2 2 1 Male sterility protein DUF1776 PF08643.10 XP_667561.1 - 0.095 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CoA_binding_2 PF13380.6 XP_667561.1 - 0.11 12.9 0.0 7 7.2 0.1 2.4 2 0 0 2 2 2 0 CoA binding domain Sdh_cyt PF01127.22 XP_667562.1 - 0.074 13.1 6.5 0.9 9.6 6.5 2.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Lig_chan PF00060.26 XP_667562.1 - 1.6 8.6 4.6 3.2 7.6 0.3 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel CAF1 PF04857.20 XP_667565.1 - 2.6e-23 82.7 8.2 1.7e-11 43.9 1.7 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease RNase_T PF00929.24 XP_667565.1 - 0.067 13.7 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 Exonuclease DUF3139 PF11337.8 XP_667567.1 - 0.14 12.8 0.1 0.5 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Helicase_C PF00271.31 XP_667568.1 - 2.1e-14 53.8 3.3 3.4e-14 53.1 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 XP_667568.1 - 2.2e-10 40.6 0.0 9e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 XP_667568.1 - 0.00016 22.4 2.0 0.00016 22.4 2.0 3.6 4 1 0 4 4 4 1 RecQ zinc-binding Antistasin PF02822.14 XP_667569.1 - 0.34 11.6 9.7 0.43 11.3 0.1 3.3 4 0 0 4 4 4 0 Antistasin family TIL PF01826.17 XP_667569.1 - 1 9.7 5.2 1.8 8.8 0.7 3.1 2 2 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain CC PF04942.14 XP_667569.1 - 1.4 9.2 4.2 4.7 7.5 0.0 3.5 4 0 0 4 4 4 0 CC domain HSA PF07529.13 XP_667570.1 - 4.5e-12 46.1 0.7 4.5e-12 46.1 0.7 3.9 5 0 0 5 5 5 1 HSA Myb_DNA-binding PF00249.31 XP_667570.1 - 0.03 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain SAP PF02037.27 XP_667571.1 - 0.14 12.0 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 SAP domain VWA_2 PF13519.6 XP_667572.1 - 1.9e-15 57.4 0.0 9.6e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Shikimate_DH PF01488.20 XP_667572.1 - 0.068 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UIM PF02809.20 XP_667572.1 - 0.12 12.3 5.2 1.3 9.2 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif V-ATPase_C PF03223.15 XP_667573.1 - 2e-94 317.1 5.1 2.5e-94 316.7 5.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Glyco_hydro_31 PF01055.26 XP_667573.1 - 0.036 13.2 0.5 0.11 11.7 0.2 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 31 SKA2 PF16740.5 XP_667573.1 - 0.076 12.8 2.5 0.91 9.3 0.0 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF4407 PF14362.6 XP_667573.1 - 0.54 9.5 1.9 1.7 7.9 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-AD PF07776.15 XP_667574.1 - 0.003 17.7 0.5 0.011 16.0 0.5 2.0 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Minor_capsid_3 PF12691.7 XP_667574.1 - 0.0061 16.9 1.2 0.012 16.0 1.2 1.5 1 0 0 1 1 1 1 Minor capsid protein from bacteriophage FlxA PF14282.6 XP_667574.1 - 0.029 14.4 3.6 0.029 14.4 3.6 2.8 3 0 0 3 3 3 0 FlxA-like protein AAA_11 PF13086.6 XP_667574.1 - 0.034 13.9 3.7 0.064 13.0 3.7 1.4 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 XP_667574.1 - 0.35 11.5 3.4 1 10.0 2.2 2.3 2 0 0 2 2 2 0 SlyX DUF2746 PF10874.8 XP_667574.1 - 0.53 10.7 2.5 7.4 7.1 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2746) DUF3958 PF13125.6 XP_667574.1 - 1 9.6 13.2 0.03 14.5 4.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3958) Pannexin_like PF12534.8 XP_667574.1 - 1.1 8.3 4.4 0.21 10.6 0.9 1.6 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 BPL_N PF09825.9 XP_667575.1 - 0.062 12.4 1.9 0.076 12.1 1.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal UQ_con PF00179.26 XP_667576.1 - 2.6e-47 160.0 0.1 2.8e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 XP_667576.1 - 8.2e-05 22.3 0.0 9.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 XP_667576.1 - 0.0037 17.5 0.1 0.0054 17.0 0.1 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 XP_667576.1 - 0.0043 16.9 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain EPL1 PF10513.9 XP_667577.1 - 2.9e-10 40.7 1.3 6e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Neogenin_C PF06583.12 XP_667577.1 - 0.019 14.8 0.7 0.019 14.8 0.7 2.2 2 0 0 2 2 2 0 Neogenin C-terminus RAP1 PF07218.11 XP_667577.1 - 0.47 8.7 7.5 0.031 12.6 1.8 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Arm-DNA-bind_5 PF17293.2 XP_667577.1 - 3.7 8.0 7.2 25 5.4 1.7 2.7 2 0 0 2 2 2 0 Arm DNA-binding domain DUF4795 PF16043.5 XP_667577.1 - 6.8 6.2 11.6 0.27 10.8 5.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Mre11_DNA_bind PF04152.14 XP_667579.1 - 1.9e-29 103.2 1.4 1.9e-29 103.2 1.4 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 XP_667579.1 - 1.1e-05 26.0 0.7 2.8e-05 24.7 0.7 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HisKA PF00512.25 XP_667580.1 - 0.32 11.1 2.8 0.25 11.4 0.6 1.9 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain PRANC PF09372.10 XP_667581.1 - 0.06 13.7 4.4 0.36 11.2 0.1 2.8 2 1 0 2 2 2 0 PRANC domain LZ3wCH PF18517.1 XP_667582.1 - 0.12 12.5 2.4 14 5.9 0.1 3.9 3 0 0 3 3 3 0 Leucine zipper with capping helix domain C8 PF08742.11 XP_667582.1 - 0.2 12.1 0.1 0.48 10.9 0.1 1.6 1 0 0 1 1 1 0 C8 domain zf-CRD PF17979.1 XP_667583.1 - 0.45 10.6 1.5 7.9 6.6 0.4 2.8 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF4710 PF15828.5 XP_667584.1 - 3.3 7.9 5.1 3.7 7.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) 7TM_GPCR_Srd PF10317.9 XP_667585.1 - 0.00046 19.5 3.0 0.00051 19.3 3.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DUF2341 PF10102.9 XP_667585.1 - 0.026 15.1 0.1 0.049 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) E1-E2_ATPase PF00122.20 XP_667585.1 - 0.15 11.5 3.8 0.089 12.3 1.4 1.7 2 0 0 2 2 2 0 E1-E2 ATPase ThrE PF06738.12 XP_667585.1 - 1.5 8.1 6.6 2.4 7.5 6.5 1.3 1 1 0 1 1 1 0 Putative threonine/serine exporter Pkinase PF00069.25 XP_667586.1 - 3e-65 220.2 0.1 4.4e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667586.1 - 2.5e-45 154.8 0.0 3.9e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_667586.1 - 0.00022 20.1 0.1 0.00061 18.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase CENP-H PF05837.12 XP_667588.1 - 0.27 11.7 8.7 0.16 12.3 0.6 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ATP-synt_D PF01813.17 XP_667588.1 - 0.77 9.5 10.1 3.4 7.5 3.4 2.5 2 0 0 2 2 2 0 ATP synthase subunit D APG6_N PF17675.1 XP_667588.1 - 0.83 10.2 11.2 1.1 9.8 2.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 XP_667588.1 - 2.4 8.2 7.2 69 3.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.29 XP_667590.1 - 1.1e-43 149.1 1.5 1.3e-43 148.8 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667590.1 - 8e-28 97.0 0.1 3e-25 88.7 0.1 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 XP_667590.1 - 0.3 11.4 3.2 1.3 9.3 1.7 2.7 2 1 0 2 2 2 0 AAA domain ACAS_N PF16177.5 XP_667591.1 - 0.09 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus zf-B_box PF00643.24 XP_667594.1 - 5.1e-06 26.5 29.5 0.00057 20.0 8.5 3.1 3 0 0 3 3 3 2 B-box zinc finger TAP35_44 PF07265.11 XP_667594.1 - 0.021 14.8 0.7 0.065 13.3 0.1 2.2 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Torus PF16131.5 XP_667596.1 - 3.1e-32 111.5 0.4 9e-32 110.0 0.4 1.8 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 XP_667596.1 - 1.2e-05 25.1 0.1 4.1e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 XP_667596.1 - 0.00029 20.8 5.0 0.00066 19.6 5.0 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 XP_667596.1 - 0.006 16.4 5.1 0.014 15.2 5.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 XP_667596.1 - 0.66 10.0 4.4 1.4 8.9 4.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tubulin PF00091.25 XP_667597.1 - 4.6e-56 190.1 0.0 9.8e-56 189.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 XP_667597.1 - 1.7e-40 138.1 0.1 2.6e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 XP_667597.1 - 0.03 14.0 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 XP_667597.1 - 0.038 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin like HEAT PF02985.22 XP_667599.1 - 5.3e-14 51.1 5.0 0.23 11.8 0.0 10.3 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 XP_667599.1 - 6.7e-13 48.8 0.7 0.89 10.0 0.0 7.6 3 3 5 8 8 8 5 HEAT repeats SF3b1 PF08920.10 XP_667599.1 - 2e-11 44.4 2.3 1e-10 42.1 2.3 2.2 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 XP_667599.1 - 6.3e-08 33.0 1.0 0.18 12.4 0.0 7.0 10 1 0 10 10 8 2 HEAT-like repeat Cnd1 PF12717.7 XP_667599.1 - 1.2e-07 31.9 0.8 1.6 8.7 0.0 6.0 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 XP_667599.1 - 4e-06 27.3 0.1 0.18 12.5 0.0 4.6 4 2 1 5 5 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 XP_667599.1 - 5.1e-06 26.2 5.1 0.021 14.4 0.1 4.4 5 1 1 6 6 6 2 CLASP N terminal UME PF08064.13 XP_667599.1 - 9.1e-06 25.5 0.5 1.2 9.1 0.0 5.4 3 2 2 5 5 5 1 UME (NUC010) domain DUF3385 PF11865.8 XP_667599.1 - 2.4e-05 24.3 7.6 0.28 11.1 0.0 5.5 5 2 0 5 5 5 2 Domain of unknown function (DUF3385) Dopey_N PF04118.14 XP_667599.1 - 0.00014 21.1 5.0 3.3 6.8 0.3 5.0 3 1 0 4 4 4 1 Dopey, N-terminal Cnd3 PF12719.7 XP_667599.1 - 0.0018 17.5 3.0 0.0059 15.8 0.2 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain NUC173 PF08161.12 XP_667599.1 - 0.0034 17.1 0.2 8.6 6.0 0.0 4.3 4 2 0 4 4 4 1 NUC173 domain MMS19_C PF12460.8 XP_667599.1 - 0.0035 16.5 4.6 0.052 12.7 0.0 4.7 7 0 0 7 7 7 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 XP_667599.1 - 0.0045 17.1 4.0 8 6.5 0.0 4.0 2 1 1 4 4 4 2 Parkin co-regulated protein DUF4042 PF13251.6 XP_667599.1 - 0.0045 16.7 0.8 17 5.1 0.0 4.4 4 2 0 4 4 4 0 Domain of unknown function (DUF4042) SNARE_assoc PF09335.11 XP_667600.1 - 0.00071 20.0 3.3 0.00071 20.0 3.3 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein PAP2 PF01569.21 XP_667600.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.3 3 1 0 3 3 3 0 PAP2 superfamily SNARE_assoc PF09335.11 XP_667601.1 - 2.3e-13 50.7 6.9 4.5e-13 49.7 5.8 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1980 PF09323.10 XP_667601.1 - 0.015 15.2 0.7 0.03 14.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3099 PF11298.8 XP_667602.1 - 2.3 8.4 5.7 0.24 11.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) SAP PF02037.27 XP_667604.1 - 6.6e-07 28.9 1.5 8.9e-07 28.5 0.3 1.9 2 0 0 2 2 2 1 SAP domain OST-HTH PF12872.7 XP_667604.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Stn1 PF10451.9 XP_667604.1 - 0.0081 15.2 6.7 0.0097 14.9 3.7 2.3 2 0 0 2 2 2 1 Telomere regulation protein Stn1 LETM1 PF07766.13 XP_667604.1 - 0.082 12.2 0.2 0.082 12.2 0.2 3.3 3 1 0 3 3 3 0 LETM1-like protein FH2 PF02181.23 XP_667605.1 - 1.8e-42 145.8 11.4 3.6e-27 95.5 5.3 2.8 3 0 0 3 3 3 2 Formin Homology 2 Domain Pkinase PF00069.25 XP_667606.1 - 1.6e-08 34.2 0.1 3.3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 XP_667606.1 - 0.0021 18.1 5.6 0.027 14.5 0.1 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 XP_667606.1 - 0.017 15.3 0.0 60 4.3 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF4407 PF14362.6 XP_667606.1 - 0.14 11.5 1.1 0.22 10.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase_fungal PF17667.1 XP_667606.1 - 0.2 10.4 2.7 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 XP_667607.1 - 8.1e-63 212.1 0.0 1.2e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 XP_667607.1 - 2.1e-55 187.9 0.0 3.8e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 XP_667607.1 - 2.7e-10 40.5 0.0 9.1e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 XP_667607.1 - 4.8e-08 33.0 0.0 2.1e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MORN PF02493.20 XP_667607.1 - 0.00036 20.2 13.0 0.51 10.3 0.1 4.2 4 0 0 4 4 4 3 MORN repeat Pkinase_fungal PF17667.1 XP_667607.1 - 0.0004 19.3 0.0 0.00092 18.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 XP_667607.1 - 0.0086 15.4 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 XP_667607.1 - 0.039 13.3 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIF_beta PF02270.15 XP_667608.1 - 2.6e-06 27.5 0.0 8.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain RPA_C PF08784.11 XP_667608.1 - 0.0011 19.6 0.2 0.0018 18.9 0.2 1.3 1 0 0 1 1 1 1 Replication protein A C terminal CAF1-p150_C2 PF15539.6 XP_667608.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term RHD3 PF05879.12 XP_667609.1 - 1.1e-85 288.4 8.1 1.7e-83 281.1 8.1 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 XP_667609.1 - 4.7e-05 22.8 0.1 0.00012 21.4 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 XP_667609.1 - 0.0001 22.4 0.1 0.00031 20.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 XP_667609.1 - 0.00055 20.2 0.2 0.0027 18.0 0.0 2.2 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 XP_667609.1 - 0.0026 17.9 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ca_hom_mod PF14798.6 XP_667609.1 - 0.0027 16.9 0.3 0.024 13.7 0.1 2.2 2 0 0 2 2 2 1 Calcium homeostasis modulator Dynamin_N PF00350.23 XP_667609.1 - 0.007 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 Dynamin family V-ATPase_G PF03179.15 XP_667610.1 - 1.7e-05 25.3 12.3 1.7e-05 25.3 12.3 2.4 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit KdpD PF02702.17 XP_667610.1 - 0.011 15.2 1.7 0.016 14.7 1.7 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain FliE PF02049.18 XP_667610.1 - 0.29 11.3 4.9 0.12 12.6 0.7 2.2 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DAGK_acc PF00609.19 XP_667611.1 - 4.5e-16 59.6 0.1 2.7e-11 44.0 0.0 3.4 3 0 0 3 3 3 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 XP_667611.1 - 4.8e-11 42.4 0.0 1.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ephrin_rec_like PF07699.13 XP_667611.1 - 0.24 11.2 5.4 0.48 10.2 1.6 2.5 2 0 0 2 2 2 0 Putative ephrin-receptor like CDC45 PF02724.14 XP_667612.1 - 8e-46 156.6 1.3 2e-28 99.1 0.1 2.1 1 1 1 2 2 2 2 CDC45-like protein DEPP PF15343.6 XP_667612.1 - 0.035 14.2 0.7 0.18 11.9 0.2 2.2 2 1 0 2 2 2 0 Decidual protein induced by progesterone family PDCD2_C PF04194.13 XP_667614.1 - 3.3e-28 98.9 1.7 3.3e-28 98.9 1.7 1.4 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Nop53 PF07767.11 XP_667617.1 - 0.013 15.0 1.7 0.024 14.0 1.7 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ATR13 PF16829.5 XP_667618.1 - 0.033 14.5 0.6 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector SAS-6_N PF16531.5 XP_667619.1 - 5e-19 68.7 5.1 9e-19 67.9 5.1 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal GDP_Man_Dehyd PF16363.5 XP_667620.1 - 2.2e-56 191.7 0.0 2.5e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 XP_667620.1 - 3.1e-48 164.4 0.0 3.7e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 XP_667620.1 - 2.4e-15 56.5 0.0 2.2e-14 53.3 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 XP_667620.1 - 3.3e-15 55.8 0.0 5.8e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 XP_667620.1 - 1.1e-09 37.8 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 XP_667620.1 - 1.2e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 XP_667620.1 - 1.6e-05 24.5 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 XP_667620.1 - 2.4e-05 23.6 0.0 0.00086 18.5 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 XP_667620.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 XP_667620.1 - 0.058 12.9 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Chal_sti_synt_N PF00195.19 XP_667620.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain UDPG_MGDP_dh_N PF03721.14 XP_667620.1 - 0.08 12.5 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 XP_667620.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GDPD PF03009.17 XP_667621.1 - 8e-42 143.7 0.0 1.1e-41 143.3 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 XP_667621.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Oxysterol_BP PF01237.18 XP_667622.1 - 2.8e-116 388.4 1.6 2.8e-116 388.4 1.6 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 XP_667622.1 - 5.9e-08 33.2 0.6 1.5e-07 31.9 0.6 1.8 1 0 0 1 1 1 1 PH domain WD40 PF00400.32 XP_667623.1 - 0.00013 22.6 10.9 0.88 10.5 0.3 5.1 5 1 1 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 XP_667623.1 - 0.29 11.7 3.0 33 5.1 1.1 3.0 3 0 0 3 3 3 0 PQQ-like domain PI-PLC-X PF00388.19 XP_667624.1 - 9.2e-59 197.2 0.0 1.7e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 XP_667624.1 - 5.9e-29 100.7 0.0 1.5e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 XP_667624.1 - 4.8e-11 41.4 0.0 0.00012 21.4 0.0 3.3 2 0 0 2 2 2 2 EF hand C2 PF00168.30 XP_667624.1 - 7.7e-11 42.2 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 XP_667624.1 - 7.7e-09 34.8 2.2 0.00059 19.6 0.1 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 XP_667624.1 - 1.4e-07 31.3 0.1 1.1e-06 28.4 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 XP_667624.1 - 2.5e-07 31.1 5.4 1.1e-05 25.8 0.5 2.8 1 1 2 3 3 3 3 EF-hand domain pair Mcp5_PH PF12814.7 XP_667624.1 - 9.9e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_5 PF13202.6 XP_667624.1 - 0.00011 21.5 1.1 0.093 12.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 XP_667624.1 - 0.00055 19.7 0.2 0.0015 18.4 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 XP_667624.1 - 0.0013 18.6 1.3 0.36 10.8 0.1 3.4 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand PH_12 PF16457.5 XP_667624.1 - 0.092 13.3 0.2 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain GDPD PF03009.17 XP_667624.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family polyprenyl_synt PF00348.17 XP_667626.1 - 7.2e-53 179.2 0.1 9.8e-53 178.8 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ipi1_N PF12333.8 XP_667626.1 - 0.0097 16.5 0.1 0.64 10.6 0.0 2.4 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation AAA PF00004.29 XP_667627.1 - 1.7e-45 154.6 0.0 4e-44 150.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 XP_667627.1 - 8.8e-10 38.4 0.1 5.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 XP_667627.1 - 4.1e-09 36.8 0.1 3e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 XP_667627.1 - 1.2e-08 35.0 0.1 4.8e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 XP_667627.1 - 1.2e-06 28.2 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 XP_667627.1 - 2.3e-06 28.1 0.3 0.00038 20.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 XP_667627.1 - 3e-05 23.3 0.0 6.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 XP_667627.1 - 3.3e-05 24.2 1.0 0.0073 16.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 XP_667627.1 - 8.5e-05 23.1 0.0 0.00024 21.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 XP_667627.1 - 9.3e-05 22.2 0.0 0.00028 20.7 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 XP_667627.1 - 0.00028 21.2 0.0 0.00057 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 XP_667627.1 - 0.00082 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 XP_667627.1 - 0.00083 19.3 0.2 0.017 15.0 0.0 2.5 3 0 0 3 3 3 1 NTPase TIP49 PF06068.13 XP_667627.1 - 0.00099 18.4 0.0 0.01 15.1 0.0 2.2 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 XP_667627.1 - 0.0013 18.6 0.1 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 XP_667627.1 - 0.0015 18.3 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 XP_667627.1 - 0.0015 17.9 0.1 0.0038 16.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 XP_667627.1 - 0.0016 18.6 0.0 0.0052 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 XP_667627.1 - 0.005 16.8 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 XP_667627.1 - 0.006 16.1 0.1 0.036 13.6 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 XP_667627.1 - 0.0076 15.8 1.8 0.072 12.7 0.2 2.5 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 XP_667627.1 - 0.0077 16.0 0.2 0.018 14.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 XP_667627.1 - 0.0085 15.8 0.3 0.11 12.2 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 XP_667627.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 XP_667627.1 - 0.017 14.8 0.3 0.041 13.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 XP_667627.1 - 0.021 14.1 0.9 0.88 8.9 0.0 2.8 3 0 0 3 3 3 0 KaiC TniB PF05621.11 XP_667627.1 - 0.022 14.2 0.0 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 XP_667627.1 - 0.027 13.6 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 XP_667627.1 - 0.03 14.3 0.2 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 XP_667627.1 - 0.058 13.3 1.0 0.66 9.8 0.0 2.5 2 1 0 3 3 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 XP_667627.1 - 0.073 12.2 0.1 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 XP_667627.1 - 0.11 12.0 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 XP_667627.1 - 0.11 12.3 0.9 0.45 10.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 XP_667627.1 - 0.16 12.5 0.1 0.62 10.6 0.1 2.2 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 XP_667627.1 - 0.18 12.0 0.2 0.81 9.8 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain MSC PF09402.10 XP_667628.1 - 0.011 15.2 0.2 0.021 14.3 0.1 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Myb_DNA-binding PF00249.31 XP_667631.1 - 6.1e-23 80.8 4.7 4.4e-11 42.8 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_667631.1 - 2.1e-18 66.3 2.2 1.1e-13 51.2 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 XP_667631.1 - 0.29 11.5 4.3 0.68 10.4 0.0 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain PHD PF00628.29 XP_667632.1 - 3.5e-06 26.8 1.9 3.5e-06 26.8 1.9 2.1 2 0 0 2 2 2 1 PHD-finger DUF3795 PF12675.7 XP_667632.1 - 0.43 11.0 1.7 1.9 9.0 1.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) PHD_4 PF16866.5 XP_667632.1 - 3.1 8.0 5.2 5.7 7.1 1.6 2.9 2 0 0 2 2 2 0 PHD-finger Diphthamide_syn PF01866.17 XP_667633.1 - 1e-76 258.3 1.2 1.5e-76 257.8 1.2 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3273 PF11677.8 XP_667634.1 - 5.9e-60 202.8 12.6 7.7e-60 202.4 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) ERGIC_N PF13850.6 XP_667634.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ycf70 PF17382.2 XP_667634.1 - 8.9 6.8 9.2 7.6 7.0 1.6 2.8 2 1 1 3 3 3 0 Uncharacterized Ycf70-like DUF3273 PF11677.8 XP_667635.1 - 3.3e-85 285.6 9.8 3.7e-85 285.4 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF996 PF06195.13 XP_667635.1 - 0.0066 16.7 12.0 0.051 13.9 3.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF996) Fumarate_red_C PF02300.17 XP_667635.1 - 0.078 13.1 0.7 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit C LRR_4 PF12799.7 XP_667636.1 - 3.6e-06 27.2 32.4 0.0016 18.8 0.4 6.4 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 XP_667636.1 - 0.001 18.8 0.2 0.001 18.8 0.2 3.9 5 1 1 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 XP_667636.1 - 0.21 11.7 10.8 79 3.7 0.2 6.5 7 0 0 7 7 7 0 Leucine Rich repeat RabGAP-TBC PF00566.18 XP_667637.1 - 5.2e-48 163.5 5.8 1.2e-47 162.4 5.8 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HTH_45 PF14947.6 XP_667637.1 - 0.6 10.1 7.9 0.087 12.8 1.9 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix GTP_EFTU PF00009.27 XP_667638.1 - 1.3e-32 112.9 0.0 1.2e-31 109.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 XP_667638.1 - 9.1e-18 64.3 0.1 2.2e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 XP_667638.1 - 1.5e-15 57.3 2.2 9.6e-10 38.7 0.2 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 XP_667638.1 - 2.3e-15 56.3 0.0 5.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 XP_667638.1 - 1.7e-07 31.3 0.0 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 XP_667638.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 XP_667638.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L5_C PF00673.21 XP_667639.1 - 8.8e-23 80.3 0.1 1.9e-22 79.2 0.0 1.5 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 XP_667639.1 - 2.1e-19 69.6 0.2 3.6e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 RRM_1 PF00076.22 XP_667641.1 - 8e-11 41.6 0.7 2.6e-07 30.4 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_667641.1 - 2e-05 24.2 3.7 5.7e-05 22.7 0.2 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 XP_667641.1 - 0.0018 18.2 0.1 0.0038 17.1 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1866) DUF4523 PF15023.6 XP_667641.1 - 0.053 13.3 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) NT-C2 PF10358.9 XP_667642.1 - 0.029 14.1 1.0 0.044 13.5 1.0 1.3 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins BK_channel_a PF03493.18 XP_667643.1 - 0.023 14.8 0.7 0.071 13.3 0.0 2.2 3 0 0 3 3 3 0 Calcium-activated BK potassium channel alpha subunit Mlf1IP PF10248.9 XP_667643.1 - 0.081 12.9 0.5 0.16 11.9 0.5 1.5 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Sec7 PF01369.20 XP_667644.1 - 8.8e-52 175.4 0.8 2.2e-51 174.1 0.8 1.8 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.18 XP_667644.1 - 8.9e-27 94.1 8.8 8.9e-27 94.1 8.8 2.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Rad9 PF04139.13 XP_667645.1 - 3.2e-15 56.3 0.1 5.7e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Rad9 INCENP_ARK-bind PF03941.15 XP_667646.1 - 1.2e-09 38.0 0.0 4.1e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Trypan_PARP PF05887.11 XP_667646.1 - 0.036 14.0 0.6 0.036 14.0 0.6 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 XP_667646.1 - 0.25 10.9 7.1 0.55 9.8 7.1 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sel1 PF08238.12 XP_667647.1 - 2e-28 98.2 15.1 4e-09 36.8 0.2 9.2 9 0 0 9 9 9 8 Sel1 repeat Ribosomal_S19 PF00203.21 XP_667648.1 - 3.4e-31 107.0 0.1 5.4e-31 106.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L4 PF00573.22 XP_667649.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 XP_667650.1 - 1.1e-18 67.1 0.1 3e-18 65.7 0.1 1.8 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.22 XP_667650.1 - 7.2e-12 45.4 0.1 4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family DHR10 PF18595.1 XP_667651.1 - 0.39 10.8 0.1 0.39 10.8 0.1 5.1 4 1 1 5 5 5 0 Designed helical repeat protein 10 domain DEAD PF00270.29 XP_667652.1 - 1.1e-40 139.2 0.0 2.1e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667652.1 - 5.1e-30 104.1 0.4 3.4e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_667652.1 - 4.3e-07 30.1 0.0 1.2e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ras PF00071.22 XP_667653.1 - 5.9e-67 224.3 0.7 6.9e-67 224.1 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 XP_667653.1 - 5e-37 126.8 0.6 7e-37 126.3 0.2 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 XP_667653.1 - 1.4e-17 63.7 0.2 1.8e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 XP_667653.1 - 1.6e-06 27.6 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 XP_667653.1 - 4.4e-06 26.4 0.5 1e-05 25.2 0.5 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 XP_667653.1 - 2.5e-05 24.3 0.1 0.00012 22.2 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 XP_667653.1 - 7.1e-05 22.8 0.3 0.12 12.3 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 XP_667653.1 - 0.00012 21.6 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NAGLU PF05089.12 XP_667653.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain AAA_16 PF13191.6 XP_667653.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 XP_667653.1 - 0.029 13.9 0.1 0.39 10.2 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 XP_667653.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 XP_667653.1 - 0.046 14.0 0.0 0.088 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 XP_667653.1 - 0.062 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 XP_667653.1 - 0.062 13.3 0.0 0.099 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 XP_667653.1 - 0.091 11.3 0.0 0.21 10.1 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein TniB PF05621.11 XP_667653.1 - 0.12 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Methyltr_RsmB-F PF01189.17 XP_667654.1 - 7.6e-66 221.6 0.0 1.5e-65 220.6 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 XP_667654.1 - 6.4e-08 33.0 0.0 1.6e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 XP_667654.1 - 0.0029 17.7 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_hydro_63N PF16923.5 XP_667654.1 - 0.019 15.0 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain Band_3_cyto PF07565.13 XP_667655.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.3 2 1 0 2 2 2 0 Band 3 cytoplasmic domain Seryl_tRNA_N PF02403.22 XP_667656.1 - 0.016 15.4 28.4 0.05 13.8 7.8 4.3 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Imm3 PF14425.6 XP_667656.1 - 0.18 11.9 8.4 0.037 14.1 2.7 2.8 2 1 1 3 3 3 0 Immunity protein Imm3 LPP PF04728.13 XP_667656.1 - 0.25 11.8 5.7 17 5.9 2.3 4.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FliJ PF02050.16 XP_667656.1 - 1.8 8.8 19.5 0.11 12.7 8.9 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein TipAS PF07739.13 XP_667656.1 - 3.5 8.2 5.4 3.2 8.3 1.4 2.4 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Occludin_ELL PF07303.13 XP_667656.1 - 9.7 7.0 11.6 4.1 8.2 1.9 3.0 1 1 1 2 2 2 0 Occludin homology domain Solute_trans_a PF03619.16 XP_667657.1 - 1.7e-74 250.7 16.5 2.3e-74 250.2 16.5 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.29 XP_667658.1 - 1.7e-15 57.2 0.0 6.1e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667658.1 - 1.2e-07 32.1 0.1 1e-05 25.8 0.1 2.7 1 1 1 2 2 2 2 Helicase conserved C-terminal domain DUF872 PF05915.12 XP_667660.1 - 8.2e-11 42.1 0.4 9e-11 42.0 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) HXXEE PF13787.6 XP_667660.1 - 0.012 16.4 0.9 0.016 16.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif RAMP4 PF06624.12 XP_667660.1 - 2 8.5 8.3 3.3 7.8 6.5 2.3 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 IMCp PF12314.8 XP_667662.1 - 2.5e-18 66.1 47.4 1.8e-13 50.6 21.7 3.2 1 1 2 3 3 3 3 Inner membrane complex protein Tim17 PF02466.19 XP_667663.1 - 1.3e-25 89.9 7.4 1.7e-25 89.5 7.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Rho_N PF07498.12 XP_667664.1 - 4.8e-06 26.4 0.1 2e-05 24.4 0.1 2.1 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain CENP-F_leu_zip PF10473.9 XP_667664.1 - 0.00024 21.2 26.1 0.00024 21.2 26.1 2.7 3 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SAP PF02037.27 XP_667664.1 - 0.0037 17.0 0.1 0.014 15.1 0.1 2.1 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 XP_667664.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.5 2 0 0 2 2 2 0 HeH/LEM domain DUF572 PF04502.13 XP_667664.1 - 5.3 6.6 33.2 6.9 6.2 33.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pro_isomerase PF00160.21 XP_667665.1 - 1.9e-49 168.0 0.0 2.2e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 XP_667665.1 - 0.037 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain UQ_con PF00179.26 XP_667666.1 - 1.8e-06 27.6 2.5 1.9e-06 27.5 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 XP_667666.1 - 0.015 15.2 0.5 0.12 12.3 0.5 2.4 1 1 0 1 1 1 0 UEV domain Apt1 PF10351.9 XP_667667.1 - 0.036 12.9 6.9 0.036 12.9 6.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CLZ PF16526.5 XP_667667.1 - 0.21 12.0 10.3 4.4 7.7 10.5 2.2 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 XP_667667.1 - 0.63 10.6 11.8 2.5 8.6 11.8 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 XP_667667.1 - 0.96 9.5 6.8 2.5 8.1 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 XP_667667.1 - 5.3 7.3 9.9 63 3.8 9.9 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein PITH PF06201.13 XP_667668.1 - 0.032 14.5 1.5 0.052 13.8 1.5 1.5 1 1 0 1 1 1 0 PITH domain DUF5605 PF18310.1 XP_667668.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) Phage_holin_3_6 PF07332.11 XP_667669.1 - 0.0068 16.4 1.4 0.0082 16.2 1.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF202 PF02656.15 XP_667669.1 - 0.048 14.1 1.2 0.072 13.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PIRT PF15099.6 XP_667669.1 - 0.15 11.7 3.4 0.29 10.7 3.4 1.5 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family PMP22_Claudin PF00822.20 XP_667669.1 - 0.16 11.9 1.9 0.23 11.3 1.9 1.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CD34_antigen PF06365.12 XP_667669.1 - 0.17 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family PsbX PF06596.11 XP_667669.1 - 0.87 9.6 7.1 0.27 11.3 1.1 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) EphA2_TM PF14575.6 XP_667669.1 - 1.5 9.8 0.0 1.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MMR_HSR1 PF01926.23 XP_667670.1 - 8.4e-15 54.9 0.0 1.5e-13 50.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_667670.1 - 1.2e-05 24.9 0.0 0.00021 20.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 XP_667670.1 - 0.0027 17.7 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase CDC45 PF02724.14 XP_667670.1 - 1.2 7.4 12.7 0.018 13.4 5.7 1.6 2 0 0 2 2 2 0 CDC45-like protein ATP_bind_2 PF03668.15 XP_667671.1 - 0.047 13.0 0.6 0.093 12.0 0.6 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family T6_Ig_like PF18002.1 XP_667671.1 - 0.097 12.5 1.1 0.24 11.3 0.3 2.0 2 0 0 2 2 2 0 T6 antigen Ig like domain YgbB PF02542.16 XP_667671.1 - 6.9 6.9 5.5 6.7 7.0 0.7 2.4 2 1 1 3 3 3 0 YgbB family TRP PF06011.12 XP_667672.1 - 0.006 15.4 3.7 0.0074 15.1 3.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel AA_permease_2 PF13520.6 XP_667672.1 - 2 7.2 14.6 2.4 6.9 14.6 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4118 PF13493.6 XP_667672.1 - 3 7.7 8.7 4.3 7.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Sigma54_activ_2 PF14532.6 XP_667673.1 - 2.4 8.3 4.8 6.2 6.9 0.2 3.7 5 0 0 5 5 5 0 Sigma-54 interaction domain NDK PF00334.19 XP_667675.1 - 2e-50 170.3 0.0 2.5e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF3541 PF12060.8 XP_667676.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) NADH-UOR_E PF16514.5 XP_667677.1 - 0.02 15.2 0.1 0.4 11.0 0.0 2.7 2 1 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E DUF948 PF06103.11 XP_667678.1 - 3.7 7.9 5.1 3.2 8.1 0.6 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3037 PF11236.8 XP_667679.1 - 0.51 10.8 3.0 0.49 10.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Roughex PF06020.11 XP_667680.1 - 4.4 6.3 11.9 7.5 5.5 11.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein DUF973 PF06157.11 XP_667681.1 - 2.7 7.0 8.3 4.7 6.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) PH_3 PF14593.6 XP_667682.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF900 PF05990.12 XP_667683.1 - 9e-24 84.3 0.0 1.7e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) ATPase PF06745.13 XP_667684.1 - 0.00023 20.6 1.5 0.0012 18.3 0.1 2.4 2 0 0 2 2 2 1 KaiC MFS_1 PF07690.16 XP_667687.1 - 6e-11 41.9 40.4 1.1e-08 34.4 21.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 XP_667687.1 - 1.2 9.1 6.8 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C MFS_1 PF07690.16 XP_667688.1 - 8.4e-06 24.9 35.9 8.4e-06 24.9 35.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GM_CSF PF01109.17 XP_667690.1 - 0.00087 19.4 0.7 0.0018 18.4 0.2 1.9 2 0 0 2 2 2 1 Granulocyte-macrophage colony-stimulating factor 30K_MP_core PF17644.1 XP_667690.1 - 0.096 12.6 0.9 0.92 9.4 0.0 2.8 2 2 2 4 4 4 0 Core domain of 30K viral movement proteins GLTSCR1 PF15249.6 XP_667691.1 - 3.2e-05 24.3 1.2 5.6e-05 23.5 0.2 2.0 1 1 1 2 2 2 1 Conserved region of unknown function on GLTSCR protein YvrJ PF12841.7 XP_667691.1 - 2.1 8.0 3.5 7.9 6.1 0.0 2.7 3 0 0 3 3 3 0 YvrJ protein family Na_H_Exchanger PF00999.21 XP_667692.1 - 1.3e-49 169.0 37.5 1.8e-49 168.6 37.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 XP_667693.1 - 4.3e-53 180.5 33.8 5.8e-53 180.0 33.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Thioredoxin PF00085.20 XP_667694.1 - 1.2e-54 182.6 0.1 2.3e-27 95.0 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 XP_667694.1 - 4.8e-19 69.0 7.7 5.2e-13 49.3 1.3 3.7 4 0 0 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 XP_667694.1 - 7e-11 42.0 1.8 4.6e-05 22.9 0.1 3.1 2 1 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 XP_667694.1 - 3.5e-10 40.3 2.4 2.6e-08 34.3 0.1 3.5 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 XP_667694.1 - 5e-09 36.4 0.5 0.035 14.4 0.0 5.6 5 2 2 7 7 6 2 Thioredoxin-like Thioredoxin_7 PF13899.6 XP_667694.1 - 5.6e-09 36.1 0.0 0.011 15.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 XP_667694.1 - 4.3e-07 29.9 0.4 0.042 13.8 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 XP_667694.1 - 3.4e-06 26.3 0.1 5.4e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 XP_667694.1 - 0.0012 18.6 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 XP_667694.1 - 0.0043 16.8 0.0 0.67 9.7 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_5 PF13743.6 XP_667694.1 - 0.08 12.6 1.1 20 4.8 0.1 3.3 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_4 PF13462.6 XP_667694.1 - 0.13 12.5 2.0 20 5.3 0.0 3.6 4 0 0 4 4 4 0 Thioredoxin Malectin PF11721.8 XP_667695.1 - 4.1e-27 95.3 0.2 5.3e-27 94.9 0.2 1.1 1 0 0 1 1 1 1 Malectin domain DUF5081 PF16887.5 XP_667695.1 - 0.04 13.0 0.3 0.069 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) LRR_4 PF12799.7 XP_667696.1 - 1.8e-23 82.2 52.4 2.9e-06 27.5 1.5 6.7 5 2 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 XP_667696.1 - 1.4e-16 60.0 35.2 7.9e-07 28.7 2.1 6.4 4 1 3 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 XP_667696.1 - 4.6e-08 32.8 22.1 0.0006 19.3 6.7 3.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 XP_667696.1 - 0.0035 17.7 39.3 2.5 9.0 0.5 9.3 9 2 0 9 9 9 3 Leucine Rich Repeat DUF2322 PF10084.9 XP_667696.1 - 0.08 13.0 0.7 0.39 10.8 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) MS_channel PF00924.18 XP_667697.1 - 3.4e-15 56.1 3.7 6.6e-15 55.2 3.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Hist_deacetyl PF00850.19 XP_667698.1 - 3.8e-81 272.9 0.0 5e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_M48_N PF16491.5 XP_667699.1 - 8e-46 156.2 13.9 8e-46 156.2 13.9 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 XP_667699.1 - 1.9e-31 109.3 0.0 4.1e-31 108.3 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 XP_667699.1 - 0.014 14.6 0.7 0.029 13.6 0.7 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 XP_667699.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Biotin_lipoyl PF00364.22 XP_667700.1 - 0.0015 18.4 0.2 6.4 6.7 0.0 4.5 3 0 0 3 3 3 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 XP_667700.1 - 0.0038 17.4 6.6 4.1 7.7 0.1 6.3 5 2 2 7 7 7 1 Peptidase family M23 QRPTase_N PF02749.16 XP_667700.1 - 0.14 12.2 0.2 47 4.1 0.0 4.1 5 0 0 5 5 5 0 Quinolinate phosphoribosyl transferase, N-terminal domain RnfC_N PF13375.6 XP_667700.1 - 0.18 11.8 7.0 3 7.9 0.2 4.8 5 0 0 5 5 5 0 RnfC Barrel sandwich hybrid domain SR-25 PF10500.9 XP_667700.1 - 4.7 6.8 23.2 11 5.6 23.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LSM PF01423.22 XP_667702.1 - 7.8e-16 57.5 2.2 9.7e-16 57.2 2.2 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 XP_667702.1 - 0.005 16.9 0.9 0.0062 16.6 0.9 1.3 1 1 0 1 1 1 1 Scd6-like Sm domain AKAP7_NLS PF10469.9 XP_667704.1 - 1.3e-29 103.6 1.9 2e-29 103.0 1.9 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 XP_667704.1 - 1.2e-05 25.4 0.0 0.047 13.9 0.1 3.4 2 1 0 2 2 2 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 XP_667704.1 - 2.1e-05 24.5 0.0 0.00015 21.7 0.0 2.2 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily SAE2 PF08573.10 XP_667705.1 - 6.3e-06 27.3 12.7 2.1e-05 25.6 0.3 3.2 2 1 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus APC_N_CC PF16689.5 XP_667705.1 - 0.23 11.6 2.7 0.34 11.0 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain PikAIV_N PF18605.1 XP_667705.1 - 0.25 10.9 4.1 0.61 9.7 4.1 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CCDC92 PF14916.6 XP_667705.1 - 0.31 10.8 3.5 0.26 11.1 0.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function WD40 PF00400.32 XP_667708.1 - 1.9e-16 60.1 5.8 0.013 16.4 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667708.1 - 1.8e-10 41.0 0.3 0.021 15.1 0.0 5.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 XP_667708.1 - 0.049 12.6 0.0 5.3 5.9 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol3_delta PF06144.13 XP_667708.1 - 0.13 12.0 3.9 0.31 10.8 3.9 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RMI1_N PF08585.12 XP_667709.1 - 1.6e-10 41.1 0.6 1.2e-08 35.0 0.6 3.0 1 1 0 1 1 1 1 RecQ mediated genome instability protein Sigma54_DBD PF04552.13 XP_667709.1 - 0.1 12.3 0.2 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Med7 PF05983.11 XP_667710.1 - 0.046 13.8 0.6 0.099 12.7 0.6 1.5 1 0 0 1 1 1 0 MED7 protein Dynein_AAA_lid PF17852.1 XP_667711.1 - 0.42 10.7 3.4 34 4.5 0.1 4.3 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain SGT1 PF07093.11 XP_667712.1 - 2.1e-19 69.4 0.0 2.1e-19 69.4 0.0 2.9 2 1 0 2 2 2 1 SGT1 protein Paramyx_P_V_C PF03210.13 XP_667712.1 - 0.024 14.5 1.0 0.092 12.5 0.0 2.2 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Adaptin_binding PF10199.9 XP_667712.1 - 2.9 8.5 11.8 6.9 7.3 11.8 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Cpn60_TCP1 PF00118.24 XP_667713.1 - 2.1e-146 488.4 4.0 2.4e-146 488.3 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 XP_667713.1 - 0.013 15.5 0.0 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 DAK2 domain DUF2529 PF10740.9 XP_667713.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) BRCT PF00533.26 XP_667713.1 - 0.16 12.4 0.1 1.4 9.3 0.0 2.5 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ribophorin_I PF04597.14 XP_667714.1 - 7.3e-76 256.1 4.9 8.6e-76 255.9 4.9 1.0 1 0 0 1 1 1 1 Ribophorin I MNSV_P7B PF06692.11 XP_667714.1 - 0.13 12.2 1.3 2.2 8.4 0.2 2.9 2 1 1 3 3 3 0 Melon necrotic spot virus P7B protein Pkinase PF00069.25 XP_667715.1 - 5.4e-32 111.2 0.0 8.3e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667715.1 - 1.7e-13 50.5 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_667715.1 - 0.00062 19.2 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 XP_667715.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Tfb4 PF03850.14 XP_667717.1 - 2.9e-06 27.0 0.1 3.9e-06 26.6 0.1 1.3 1 1 0 1 1 1 1 Transcription factor Tfb4 WSS_VP PF12175.8 XP_667717.1 - 0.035 13.6 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP CS PF04969.16 XP_667718.1 - 4.9e-06 27.5 0.4 9.4e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 CS domain HEAT PF02985.22 XP_667720.1 - 3.2e-09 36.2 8.6 0.84 10.1 0.0 7.4 9 0 0 9 9 9 4 HEAT repeat Cnd1 PF12717.7 XP_667720.1 - 9.2e-07 29.0 0.8 0.78 9.8 0.4 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 XP_667720.1 - 6.7e-06 26.4 0.0 4.5 7.7 0.0 5.3 6 0 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 XP_667720.1 - 0.0083 16.7 0.5 0.21 12.2 0.2 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 XP_667720.1 - 0.045 14.3 0.1 88 3.8 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat Hydrolase_4 PF12146.8 XP_667722.1 - 6.2e-12 45.3 0.0 5.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 XP_667722.1 - 1.7e-07 31.0 0.0 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 XP_667722.1 - 1e-06 28.6 0.0 0.00046 19.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 XP_667722.1 - 1.8e-06 28.7 0.0 0.00042 21.0 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 XP_667722.1 - 7.3e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 XP_667722.1 - 0.027 14.3 0.0 5.8 6.7 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 XP_667722.1 - 0.031 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 XP_667722.1 - 0.042 13.4 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 XP_667722.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cpn60_TCP1 PF00118.24 XP_667723.1 - 1.2e-81 274.8 1.0 2.3e-81 273.9 1.0 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 XP_667724.1 - 9.5e-16 57.9 4.9 2.5e-15 56.6 2.9 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667724.1 - 1.6e-08 34.2 0.5 3e-08 33.3 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 XP_667724.1 - 0.019 13.7 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 XP_667724.1 - 0.025 13.9 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 Kinase-like MEIOC PF15189.6 XP_667726.1 - 0.053 13.1 1.4 0.11 12.1 1.4 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC ANAPC4_WD40 PF12894.7 XP_667728.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Sec66 PF09802.9 XP_667730.1 - 3.8e-06 26.6 4.2 5.3e-06 26.1 4.2 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4271 PF14093.6 XP_667730.1 - 0.018 14.9 0.7 0.028 14.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) TssO PF17561.2 XP_667730.1 - 0.061 13.4 0.5 0.061 13.4 0.5 3.3 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF4061 PF13270.6 XP_667730.1 - 0.12 12.7 7.7 0.056 13.8 5.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Dynamin_M PF01031.20 XP_667731.1 - 1.5e-82 277.0 0.0 1.5e-82 277.0 0.0 2.5 3 1 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 XP_667731.1 - 5.3e-29 101.4 0.0 5.3e-29 101.4 0.0 2.4 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 XP_667731.1 - 2.8e-24 85.1 1.1 2.8e-24 85.1 1.1 3.5 4 0 0 4 4 4 1 Dynamin GTPase effector domain Matrilin_ccoil PF10393.9 XP_667731.1 - 0.018 14.9 0.1 1 9.3 0.0 3.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Peptidase_M41 PF01434.18 XP_667731.1 - 0.12 12.2 0.3 0.42 10.4 0.3 1.9 1 0 0 1 1 1 0 Peptidase family M41 HSBP1 PF06825.12 XP_667731.1 - 0.12 12.3 4.8 33 4.5 0.0 4.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Mito_carr PF00153.27 XP_667733.1 - 7.5e-43 144.4 0.8 7.1e-17 61.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 XP_667733.1 - 0.074 12.2 0.3 0.79 8.8 0.2 2.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease DUF3021 PF11457.8 XP_667733.1 - 0.25 11.7 4.2 0.51 10.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Utp11 PF03998.13 XP_667734.1 - 2.2e-33 116.2 2.5 2.6e-33 116.0 2.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 XP_667734.1 - 0.0031 16.9 0.8 0.0042 16.4 0.8 1.4 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 Bt_P21 PF05560.11 XP_667734.1 - 0.067 12.8 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Utp11 PF03998.13 XP_667735.1 - 1e-10 42.0 8.1 1.1e-10 41.9 8.1 1.0 1 0 0 1 1 1 1 Utp11 protein SNARE PF05739.19 XP_667735.1 - 0.28 11.2 2.1 0.93 9.5 0.0 2.1 2 0 0 2 2 2 0 SNARE domain SlyX PF04102.12 XP_667736.1 - 0.062 13.9 1.4 0.062 13.9 1.4 4.2 1 1 1 3 3 3 0 SlyX DUF3993 PF13158.6 XP_667736.1 - 6 7.1 6.5 2.6 8.3 1.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3993) PARM PF17061.5 XP_667736.1 - 8.4 6.4 9.0 2.1 8.4 5.3 1.8 1 1 0 1 1 1 0 PARM Ecotin PF03974.13 XP_667737.1 - 0.049 13.6 0.3 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 Ecotin DUF5470 PF17564.2 XP_667737.1 - 0.31 11.3 4.5 0.42 10.9 1.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5470) PilM PF07419.12 XP_667738.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 PilM Cor1 PF04803.12 XP_667738.1 - 0.27 11.5 6.5 0.09 13.0 3.0 2.0 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF1759 PF03564.15 XP_667738.1 - 0.37 10.7 7.1 0.35 10.8 1.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) MS_channel PF00924.18 XP_667739.1 - 9.3e-18 64.5 2.1 2.1e-17 63.4 2.1 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3464 PF11947.8 XP_667740.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PA14 PF07691.12 XP_667741.1 - 4.2e-27 94.8 0.0 8.1e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 XP_667741.1 - 0.0002 21.7 0.0 0.00093 19.6 0.0 2.1 2 0 0 2 2 2 1 GLEYA domain fn2 PF00040.19 XP_667741.1 - 0.012 15.9 2.3 0.012 15.9 2.3 1.9 2 0 0 2 2 2 0 Fibronectin type II domain FliJ PF02050.16 XP_667741.1 - 0.031 14.5 3.5 0.94 9.7 0.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 XP_667741.1 - 0.052 13.1 0.6 0.086 12.4 0.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSBP1 PF06825.12 XP_667741.1 - 1.4 8.9 4.6 3.3 7.7 1.1 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Aa_trans PF01490.18 XP_667742.1 - 2.4e-49 168.2 31.6 1.1e-48 165.9 31.6 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein NCOA_u2 PF16665.5 XP_667742.1 - 0.41 11.0 5.3 0.81 10.0 5.3 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein DUF1761 PF08570.10 XP_667742.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) PP2C PF00481.21 XP_667743.1 - 3.8e-06 26.7 0.0 0.067 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 XP_667743.1 - 8e-06 25.9 0.0 0.00065 19.7 0.0 3.4 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) FAM104 PF15434.6 XP_667743.1 - 2 9.0 8.7 0.28 11.7 0.4 2.7 2 0 0 2 2 2 0 Family 104 GST_C_3 PF14497.6 XP_667744.1 - 0.0023 18.1 0.1 0.032 14.4 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain S1-P1_nuclease PF02265.16 XP_667744.1 - 0.048 13.5 0.1 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 S1/P1 Nuclease YpsA PF06908.11 XP_667744.1 - 0.062 13.3 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 YspA SLOG family RNA_pol_Rpb6 PF01192.22 XP_667745.1 - 6.8e-18 64.3 0.1 1.3e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 40S_S4_C PF16121.5 XP_667746.1 - 5.3e-21 74.0 0.1 6.8e-21 73.6 0.1 1.1 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 XP_667746.1 - 0.0037 17.2 0.2 0.0073 16.2 0.2 1.6 1 1 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.20 XP_667747.1 - 3.4e-28 97.4 1.5 3.6e-28 97.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 XP_667747.1 - 1.9e-08 34.3 0.1 3e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 XP_667747.1 - 2.7e-08 33.4 0.0 4.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain GDI PF00996.18 XP_667749.1 - 1.5e-34 119.3 7.0 3e-16 59.0 0.5 3.5 3 1 0 3 3 3 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 XP_667749.1 - 0.028 14.6 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SspH PF08141.12 XP_667749.1 - 0.06 13.5 1.2 0.64 10.2 0.0 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein H family UBA PF00627.31 XP_667750.1 - 3.6e-28 97.1 5.7 2.9e-14 52.6 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 XP_667750.1 - 5.8e-22 77.2 5.9 1.5e-21 75.9 5.9 1.7 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 XP_667750.1 - 8.9e-17 60.6 0.4 1.6e-16 59.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 XP_667750.1 - 3.9e-09 36.2 0.8 6.9e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 XP_667750.1 - 2.1e-07 31.4 0.8 5.2e-07 30.2 0.8 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 XP_667750.1 - 1.5e-06 28.3 1.2 3.1e-06 27.2 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 XP_667750.1 - 7.5e-06 25.7 0.0 0.039 13.8 0.0 2.9 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 XP_667750.1 - 0.001 19.4 1.1 0.0023 18.3 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 XP_667750.1 - 0.011 16.4 0.0 0.035 14.8 0.0 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 XP_667750.1 - 0.068 13.2 1.7 3.3 7.8 0.9 2.6 1 1 1 2 2 2 0 Ubiquitin-like domain Coilin_N PF15862.5 XP_667750.1 - 0.15 11.9 1.6 0.25 11.1 1.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus CUE PF02845.16 XP_667750.1 - 0.15 11.8 1.1 16 5.3 0.0 3.2 2 1 1 3 3 3 0 CUE domain DUF3306 PF11748.8 XP_667750.1 - 0.37 11.7 3.5 0.17 12.8 0.8 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3306) FlaG PF03646.15 XP_667750.1 - 5.8 7.1 9.7 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 FlaG protein START PF01852.19 XP_667752.1 - 0.0011 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 START domain PHD PF00628.29 XP_667753.1 - 0.27 11.1 9.0 0.14 12.0 5.4 2.0 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 XP_667753.1 - 0.46 10.8 8.0 2.2 8.6 5.4 2.2 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 XP_667753.1 - 0.56 10.6 12.3 2.4 8.5 12.5 1.9 1 1 1 2 2 2 0 Ring finger domain C1_1 PF00130.22 XP_667753.1 - 0.71 9.8 8.2 0.31 11.0 5.5 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 XP_667753.1 - 0.96 9.4 7.9 0.3 11.0 4.7 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 XP_667753.1 - 1.7 8.8 11.4 3.7 7.8 10.7 1.9 1 1 1 2 2 2 0 RING-variant domain TcA_TcB_BD PF18276.1 XP_667754.1 - 0.0057 15.8 0.1 0.0085 15.2 0.1 1.2 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Vma12 PF11712.8 XP_667755.1 - 0.72 9.9 3.4 0.43 10.6 0.5 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Patatin PF01734.22 XP_667756.1 - 1e-14 55.2 0.0 2.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Fzo_mitofusin PF04799.13 XP_667756.1 - 0.02 14.5 0.8 0.047 13.2 0.8 1.6 1 0 0 1 1 1 0 fzo-like conserved region DASH_Duo1 PF08651.10 XP_667756.1 - 0.64 9.8 5.7 0.65 9.8 3.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 SNF5 PF04855.12 XP_667758.1 - 0.00041 20.2 0.1 0.00075 19.4 0.1 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HNF-1_N PF04814.13 XP_667758.1 - 0.0041 17.8 0.0 0.0041 17.8 0.0 2.9 4 0 0 4 4 4 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus VLPT PF07122.11 XP_667759.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Pkinase PF00069.25 XP_667760.1 - 2.4e-49 168.1 0.0 4.2e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667760.1 - 3.1e-47 161.1 0.0 4.1e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 XP_667760.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 XP_667760.1 - 0.02 14.3 0.0 0.048 13.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Phage_integrase PF00589.22 XP_667761.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family MFS_1 PF07690.16 XP_667762.1 - 8.6e-22 77.5 38.1 1.7e-20 73.3 3.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 XP_667762.1 - 3.5e-15 55.8 1.9 3.5e-15 55.8 1.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 XP_667762.1 - 3.6e-07 28.9 27.3 0.00021 19.8 15.7 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Tir_receptor_C PF07489.11 XP_667762.1 - 0.018 15.0 0.7 0.035 14.1 0.7 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Sigma_reg_N PF13800.6 XP_667762.1 - 0.65 10.3 8.5 1.9 8.8 1.3 3.7 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Bromodomain PF00439.25 XP_667763.1 - 0.00074 19.5 0.0 0.0022 18.0 0.0 1.8 1 1 0 1 1 1 1 Bromodomain Phage_min_tail PF05939.13 XP_667763.1 - 0.028 14.8 0.1 0.17 12.2 0.0 2.1 2 1 0 2 2 2 0 Phage minor tail protein Coatomer_b_Cpla PF14806.6 XP_667763.1 - 0.048 13.7 0.6 0.11 12.5 0.6 1.7 1 1 0 1 1 1 0 Coatomer beta subunit appendage platform tRNA_int_end_N2 PF12928.7 XP_667763.1 - 0.059 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term HypA PF01155.19 XP_667764.1 - 0.0065 16.5 0.4 0.025 14.6 0.1 2.1 3 0 0 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pkinase PF00069.25 XP_667765.1 - 0.13 11.6 1.7 0.24 10.7 0.7 1.7 2 0 0 2 2 2 0 Protein kinase domain CTP_transf_like PF01467.26 XP_667766.1 - 0.0024 18.1 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_L1 PF00687.21 XP_667767.1 - 3.2e-45 154.4 5.3 3.9e-45 154.1 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Leo1 PF04004.13 XP_667768.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Leo1-like protein Helicase_C_2 PF13307.6 XP_667769.1 - 4.1e-48 163.8 0.1 5.4e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Ccdc124 PF06244.12 XP_667770.1 - 1.2e-32 113.2 4.0 1.4e-32 113.0 4.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 XP_667770.1 - 2.3e-06 27.9 1.1 4.2e-06 27.1 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 XP_667770.1 - 0.027 15.0 0.2 0.031 14.8 0.2 1.1 1 0 0 1 1 1 0 YABBY protein CHDNT PF08073.12 XP_667770.1 - 0.043 13.8 0.4 0.043 13.8 0.4 1.7 2 0 0 2 2 2 0 CHDNT (NUC034) domain DUF1002 PF06207.11 XP_667770.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Proteasome PF00227.26 XP_667771.1 - 4.4e-47 160.0 0.4 4.9e-47 159.9 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit Strep_pep PF14404.6 XP_667772.1 - 0.15 12.4 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species PIG-P PF08510.12 XP_667773.1 - 2.5e-25 88.7 0.1 1e-24 86.8 0.1 1.8 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.12 XP_667773.1 - 0.11 12.9 2.2 0.18 12.1 2.2 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF846 PF05832.12 XP_667774.1 - 9.8e-42 142.3 20.8 1.3e-41 141.9 20.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SUI1 PF01253.22 XP_667775.1 - 1.6e-24 86.2 0.0 2.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 EF-hand_1 PF00036.32 XP_667776.1 - 1.2e-38 127.8 11.5 3.6e-09 35.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_667776.1 - 6.8e-33 112.9 3.3 1.7e-16 60.4 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_667776.1 - 1e-28 96.8 6.9 2.9e-09 36.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 XP_667776.1 - 4.5e-28 96.9 12.8 5e-14 51.9 1.2 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_667776.1 - 4.7e-24 82.8 9.4 3.8e-06 26.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 XP_667776.1 - 5.2e-13 49.1 0.1 3.7e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 XP_667776.1 - 4.9e-08 32.9 0.5 0.0019 18.2 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 XP_667776.1 - 2.3e-07 31.1 0.2 0.0093 16.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 XP_667776.1 - 7.2e-05 22.7 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 XP_667776.1 - 0.0001 23.1 0.0 0.01 16.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 XP_667776.1 - 0.0019 18.4 4.3 0.13 12.5 0.3 3.1 1 1 3 4 4 4 1 Dockerin type I domain DUF3349 PF11829.8 XP_667776.1 - 0.0019 18.9 0.2 2.6 8.9 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 XP_667776.1 - 0.0024 17.9 0.5 0.0078 16.3 0.1 2.1 2 2 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 XP_667776.1 - 0.0032 17.4 0.2 1.1 9.2 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 XP_667776.1 - 0.0032 17.4 0.2 0.68 9.8 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein MotA_activ PF09114.10 XP_667776.1 - 0.0068 16.5 0.0 0.089 12.9 0.0 2.1 2 0 0 2 2 2 1 Transcription factor MotA, activation domain YqeY PF09424.10 XP_667776.1 - 0.015 15.3 0.1 0.31 11.1 0.0 2.1 1 1 1 2 2 2 0 Yqey-like protein RNA_pol_Rpb4 PF03874.16 XP_667776.1 - 0.05 13.9 0.9 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF1811 PF08838.10 XP_667776.1 - 0.085 13.1 0.0 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) SapB_1 PF05184.15 XP_667776.1 - 0.089 12.8 3.3 4.5 7.4 0.0 3.2 4 0 0 4 4 4 0 Saposin-like type B, region 1 SUB1_ProdP9 PF18213.1 XP_667776.1 - 0.26 11.1 2.4 4.4 7.2 0.1 2.9 1 1 2 3 3 3 0 SUB1 protease Prodomain ProdP9 MFS_1 PF07690.16 XP_667777.1 - 5.3e-14 51.9 37.0 1.2e-12 47.5 31.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily LCCL PF03815.19 XP_667778.1 - 6.8e-88 289.0 18.8 5.5e-24 84.1 0.4 5.0 5 0 0 5 5 5 4 LCCL domain SRCR PF00530.18 XP_667778.1 - 1.3e-34 118.7 12.8 1.7e-17 63.8 6.8 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.6 XP_667778.1 - 1.2e-17 64.4 0.4 3.2e-17 63.1 0.4 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PLAT PF01477.23 XP_667778.1 - 2.1e-14 54.1 0.1 2.2e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 PLAT/LH2 domain Rxt3 PF08642.10 XP_667778.1 - 4.9e-09 37.0 0.0 0.017 15.9 0.2 4.5 4 1 0 4 4 4 2 Histone deacetylation protein Rxt3 SRCR_2 PF15494.6 XP_667778.1 - 1.5e-05 25.4 6.2 9.5e-05 22.9 2.0 2.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Pentaxin PF00354.17 XP_667778.1 - 6.2e-05 22.8 0.1 0.00013 21.7 0.1 1.4 1 0 0 1 1 1 1 Pentaxin family Sialidase PF02973.16 XP_667778.1 - 0.00022 20.8 0.3 0.0005 19.6 0.3 1.6 1 0 0 1 1 1 1 Sialidase, N-terminal domain Hepsin-SRCR PF09272.10 XP_667778.1 - 0.095 13.2 0.5 7 7.2 0.2 2.7 2 0 0 2 2 2 0 Hepsin, SRCR domain Bac_surface_Ag PF01103.23 XP_667780.1 - 6.7e-15 55.4 8.4 1.2e-14 54.6 8.4 1.4 1 1 0 1 1 1 1 Surface antigen IBN_N PF03810.19 XP_667780.1 - 0.036 14.0 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain SNAP PF14938.6 XP_667781.1 - 1e-60 205.6 16.4 1.2e-57 195.5 16.4 2.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 XP_667781.1 - 0.00011 22.8 1.9 17 6.2 0.0 5.2 5 0 0 5 5 5 1 Sel1 repeat TPR_12 PF13424.6 XP_667781.1 - 0.00028 21.1 6.3 0.049 13.9 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_667781.1 - 0.0018 18.2 16.5 0.48 10.7 0.3 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_667781.1 - 0.26 11.2 0.1 0.26 11.2 0.1 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 XP_667781.1 - 0.28 11.3 15.3 1.8 8.7 0.1 5.3 4 2 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 XP_667781.1 - 0.33 11.1 7.2 52 4.2 0.0 5.2 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 XP_667781.1 - 1.1 9.7 0.1 1.1 9.7 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat NSF PF02071.20 XP_667781.1 - 1.8 9.7 9.5 74 4.8 0.2 6.3 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat WD40 PF00400.32 XP_667782.1 - 3.9e-12 46.5 1.6 0.054 14.4 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_667782.1 - 0.01 16.1 0.0 14 6.1 0.0 4.3 2 1 4 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Dynein_light PF01221.18 XP_667783.1 - 7.3e-42 141.6 1.0 8.1e-42 141.5 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Tau95 PF09734.9 XP_667784.1 - 1.9e-28 100.0 0.0 5e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 XP_667784.1 - 9.3e-14 51.7 0.1 1.2e-10 41.6 0.0 2.8 2 1 1 3 3 3 2 Tau95 Triple barrel domain Vps5 PF09325.10 XP_667785.1 - 0.0076 15.8 4.2 0.013 15.1 4.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like SCVP PF17619.2 XP_667785.1 - 0.18 12.7 1.4 1.4 9.9 0.0 2.8 2 1 1 3 3 3 0 Secreted clade V proteins Peptidase_C97 PF05903.14 XP_667786.1 - 2.3e-29 102.2 0.0 4.8e-29 101.1 0.0 1.5 2 0 0 2 2 2 1 PPPDE putative peptidase domain ALMT PF11744.8 XP_667788.1 - 0.057 12.3 2.8 0.1 11.4 2.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Apt1 PF10351.9 XP_667788.1 - 0.16 10.8 11.5 0.25 10.2 11.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L29 PF00831.23 XP_667788.1 - 2.2 8.3 6.1 1 9.4 0.2 3.1 3 1 0 3 3 3 0 Ribosomal L29 protein DUF4614 PF15391.6 XP_667788.1 - 3.1 7.7 14.4 6.2 6.8 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Transformer PF06495.11 XP_667788.1 - 8.4 6.4 20.3 13 5.8 20.3 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF382 PF04037.13 XP_667789.1 - 1.4e-52 177.2 0.2 1.4e-52 177.2 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 XP_667789.1 - 1.5e-19 69.5 6.1 3.1e-19 68.6 6.1 1.5 1 0 0 1 1 1 1 PSP PTPlike_phytase PF14566.6 XP_667789.1 - 0.065 13.3 0.4 0.065 13.3 0.4 3.4 3 1 0 3 3 3 0 Inositol hexakisphosphate QIL1 PF15884.5 XP_667790.1 - 0.017 15.7 2.5 1.4 9.6 0.4 3.7 3 1 1 4 4 4 0 MICOS complex subunit MIC13, QIL1 AP2 PF00847.20 XP_667791.1 - 2.7e-12 46.7 2.6 5.1e-12 45.8 2.6 1.5 1 0 0 1 1 1 1 AP2 domain MCU PF04678.13 XP_667791.1 - 0.18 11.9 1.4 1.3 9.1 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RskA PF10099.9 XP_667791.1 - 1.3 9.3 8.6 1.5 9.1 1.4 2.7 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Tweety PF04906.13 XP_667791.1 - 4.8 5.7 7.2 11 4.5 7.2 1.5 1 0 0 1 1 1 0 Tweety BRF1 PF07741.13 XP_667791.1 - 6.7 7.1 16.6 1.1 9.7 10.1 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Baculo_PEP_C PF04513.12 XP_667793.1 - 0.0069 16.4 3.1 0.0069 16.4 3.1 2.0 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 XP_667793.1 - 0.0082 16.0 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 XP_667793.1 - 0.013 15.1 1.7 0.026 14.1 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF5617 PF18493.1 XP_667793.1 - 0.037 14.1 1.6 0.7 10.0 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) DUF1664 PF07889.12 XP_667793.1 - 0.078 13.0 1.4 0.24 11.4 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 XP_667793.1 - 0.29 11.1 4.7 0.99 9.4 4.7 1.9 1 1 0 1 1 1 0 Prefoldin subunit CHIP_TPR_N PF18391.1 XP_667793.1 - 0.35 11.7 4.5 0.27 12.0 1.4 2.3 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Pex19 PF04614.12 XP_667793.1 - 0.59 9.9 3.7 2.2 8.0 0.4 2.1 2 0 0 2 2 2 0 Pex19 protein family DUF4665 PF15679.5 XP_667793.1 - 0.89 10.2 4.7 1.3 9.7 1.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Fib_alpha PF08702.10 XP_667793.1 - 4.3 7.5 10.9 0.66 10.2 6.1 2.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-CHY PF05495.12 XP_667794.1 - 1.2e-12 48.1 11.6 1.2e-12 48.1 11.6 3.7 2 1 1 3 3 3 1 CHY zinc finger Myb_DNA-binding PF00249.31 XP_667794.1 - 1.8e-07 31.3 0.2 4.2e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Trs65 PF12735.7 XP_667794.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 zinc_ribbon_12 PF11331.8 XP_667794.1 - 0.99 9.3 12.4 0.34 10.7 3.0 4.0 3 1 1 4 4 4 0 Probable zinc-ribbon domain UCH PF00443.29 XP_667795.1 - 3.8e-37 128.2 2.4 5e-37 127.8 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_667795.1 - 7.8e-08 32.3 9.4 1.1e-06 28.5 9.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 XP_667795.1 - 1.9 8.5 6.9 3.9 7.4 0.6 2.4 2 0 0 2 2 2 0 HIT zinc finger Telomerase_RBD PF12009.8 XP_667796.1 - 3.4e-21 75.7 6.8 3.4e-21 75.7 6.8 3.1 3 1 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain SR-25 PF10500.9 XP_667796.1 - 0.021 14.5 12.4 0.057 13.0 12.4 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AMPK1_CBM PF16561.5 XP_667798.1 - 4.6e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase IQ PF00612.27 XP_667798.1 - 0.00022 20.7 8.3 1.6 8.7 0.1 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif DUF4860 PF16152.5 XP_667798.1 - 0.31 10.9 1.6 5.2 7.0 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4860) IQ PF00612.27 XP_667799.1 - 3.8e-09 35.5 8.2 0.00065 19.3 0.8 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif SF-assemblin PF06705.11 XP_667800.1 - 9.8 5.4 12.8 0.58 9.4 2.6 3.3 3 1 0 3 3 3 0 SF-assemblin/beta giardin PFK PF00365.20 XP_667801.1 - 7.2e-52 176.5 2.9 8.8e-40 136.8 0.8 3.5 2 2 0 2 2 2 2 Phosphofructokinase Seryl_tRNA_N PF02403.22 XP_667801.1 - 6.5 7.0 9.0 1.2 9.4 2.6 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3347 PF11827.8 XP_667802.1 - 0.29 11.3 2.4 0.94 9.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) zf-U1 PF06220.12 XP_667803.1 - 0.00037 20.2 1.3 0.00085 19.1 1.3 1.7 1 0 0 1 1 1 1 U1 zinc finger DUF3906 PF13046.6 XP_667803.1 - 0.18 11.9 1.0 0.49 10.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) AAA PF00004.29 XP_667804.1 - 1.4e-15 57.9 0.0 2.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 XP_667804.1 - 1.6e-14 54.0 0.0 8.2e-14 51.8 0.0 2.2 2 1 1 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 XP_667804.1 - 2.5e-12 46.9 0.1 2.2e-10 40.6 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 XP_667804.1 - 1.5e-07 32.0 0.3 7e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 XP_667804.1 - 1.7e-06 27.9 0.2 8.2e-06 25.7 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 XP_667804.1 - 2e-06 27.9 0.1 1.2e-05 25.3 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 XP_667804.1 - 2.2e-06 27.7 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 XP_667804.1 - 8e-05 22.9 0.7 0.074 13.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 XP_667804.1 - 0.00012 22.1 0.4 0.00066 19.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 XP_667804.1 - 0.00022 20.7 0.1 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_667804.1 - 0.00034 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 XP_667804.1 - 0.00037 20.4 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 XP_667804.1 - 0.00039 20.8 0.5 0.017 15.4 0.1 2.6 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 XP_667804.1 - 0.00077 19.4 1.1 0.26 11.2 0.1 2.2 1 1 1 2 2 2 2 NTPase TniB PF05621.11 XP_667804.1 - 0.0012 18.3 0.2 0.062 12.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 XP_667804.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 XP_667804.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 XP_667804.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 XP_667804.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 XP_667804.1 - 0.0047 17.5 0.0 0.0078 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 XP_667804.1 - 0.009 16.4 0.1 0.044 14.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 XP_667804.1 - 0.01 15.4 0.0 0.036 13.6 0.0 1.9 2 1 0 2 2 1 0 AAA domain T2SSE PF00437.20 XP_667804.1 - 0.012 14.7 0.1 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 XP_667804.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 XP_667804.1 - 0.015 14.7 0.2 0.48 9.7 0.1 2.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.6 XP_667804.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 XP_667804.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain MeaB PF03308.16 XP_667804.1 - 0.032 13.2 0.1 0.18 10.8 0.1 1.9 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 XP_667804.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 XP_667804.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 XP_667804.1 - 0.057 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain DEAD PF00270.29 XP_667804.1 - 0.061 13.1 0.5 1.6 8.5 0.1 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.6 XP_667804.1 - 0.063 13.4 0.1 0.39 10.8 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.10 XP_667804.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 XP_667804.1 - 0.16 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 XP_667804.1 - 0.16 11.7 0.1 18 5.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SecA_DEAD PF07517.14 XP_667804.1 - 0.18 11.1 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain GAF_2 PF13185.6 XP_667805.1 - 0.088 13.1 0.0 21 5.4 0.0 3.2 4 0 0 4 4 4 0 GAF domain DSPc PF00782.20 XP_667806.1 - 4.3e-26 91.3 0.0 1.5e-25 89.5 0.0 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 XP_667806.1 - 0.0039 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_11 PF08279.12 XP_667806.1 - 0.22 11.5 0.8 12 5.9 0.0 3.3 3 0 0 3 3 3 0 HTH domain PP2C PF00481.21 XP_667807.1 - 8.2e-20 71.5 0.0 1.1e-12 48.2 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C tRNA_anti-codon PF01336.25 XP_667808.1 - 0.02 14.9 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RMI2 PF16100.5 XP_667808.1 - 0.02 14.7 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Peroxin-13_N PF04088.13 XP_667809.1 - 0.0012 19.2 0.4 0.94 9.8 0.1 2.3 2 0 0 2 2 2 2 Peroxin 13, N-terminal region FH2 PF02181.23 XP_667809.1 - 0.0099 15.0 1.8 0.044 12.9 1.2 2.4 1 1 0 1 1 1 1 Formin Homology 2 Domain LOH1CR12 PF10158.9 XP_667809.1 - 0.12 12.4 0.4 1.2 9.1 0.0 2.7 2 1 0 2 2 2 0 Tumour suppressor protein Pkinase PF00069.25 XP_667810.1 - 1.2e-70 237.9 0.0 1.3e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667810.1 - 1.3e-34 119.7 0.0 1.6e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 XP_667810.1 - 0.0036 17.3 0.0 0.0079 16.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 XP_667810.1 - 0.034 13.7 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 XP_667810.1 - 0.13 11.2 0.0 0.35 9.8 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 XP_667810.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EF-hand_1 PF00036.32 XP_667813.1 - 1.1e-28 96.5 7.5 1.4e-08 33.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_667813.1 - 2.2e-26 92.1 4.1 1e-14 54.7 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_667813.1 - 1.2e-23 81.0 5.8 2e-08 33.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 XP_667813.1 - 3.5e-17 62.0 7.0 1.1e-09 38.0 0.5 3.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_667813.1 - 7.9e-15 53.6 7.4 2.3e-06 26.8 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 XP_667813.1 - 1.9e-11 44.1 0.2 3.5e-06 27.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 XP_667813.1 - 3.5e-05 24.1 0.5 0.067 13.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 XP_667813.1 - 4.5e-05 23.3 2.4 0.077 13.0 0.1 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 XP_667813.1 - 4.6e-05 23.4 0.1 0.0067 16.4 0.0 2.8 2 1 1 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.13 XP_667813.1 - 0.0015 18.5 0.1 0.82 9.6 0.0 2.9 2 1 1 3 3 3 1 Caleosin related protein SUB1_ProdP9 PF18213.1 XP_667813.1 - 0.0034 17.2 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 SPARC_Ca_bdg PF10591.9 XP_667813.1 - 0.01 16.1 0.1 4.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1257 PF06868.11 XP_667813.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Toprim_2 PF13155.6 XP_667813.1 - 0.046 14.2 0.4 0.34 11.4 0.1 2.1 1 1 1 2 2 2 0 Toprim-like EF-hand_11 PF08976.11 XP_667813.1 - 0.056 14.3 0.1 0.9 10.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DUF3008 PF11450.8 XP_667813.1 - 0.062 13.5 1.0 0.12 12.6 0.1 1.9 2 0 0 2 2 1 0 Protein of unknwon function (DUF3008) Nexin_C PF08628.12 XP_667813.1 - 0.073 13.7 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Sorting nexin C terminal DUF591 PF04569.14 XP_667813.1 - 0.12 12.4 0.4 0.26 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function Skp1 PF01466.19 XP_667813.1 - 0.22 11.7 1.1 8.5 6.6 0.1 2.7 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Clathrin PF00637.20 XP_667814.1 - 3.7e-145 477.5 61.6 2e-30 105.6 2.0 9.8 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 XP_667814.1 - 9.4e-15 54.3 0.7 1.8e-12 47.0 0.0 4.1 5 0 0 5 5 5 1 Clathrin-H-link TPR_8 PF13181.6 XP_667814.1 - 0.00073 19.6 1.9 2.9 8.3 0.1 4.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 XP_667814.1 - 0.0021 18.0 0.1 28 5.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 XP_667814.1 - 0.0024 17.8 0.3 61 4.1 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Clathrin_propel PF01394.20 XP_667814.1 - 0.0096 16.2 0.0 7.9 7.0 0.0 3.3 2 0 0 2 2 2 1 Clathrin propeller repeat Mic1 PF07035.12 XP_667814.1 - 0.019 14.7 10.5 0.023 14.4 4.0 3.7 4 0 0 4 4 4 0 Colon cancer-associated protein Mic1-like DUF4965 PF16335.5 XP_667814.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) TPR_1 PF00515.28 XP_667814.1 - 0.11 12.4 11.9 6.1 6.8 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 XP_667814.1 - 0.15 12.3 1.8 1.3e+02 2.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_667814.1 - 0.3 11.4 6.4 5.8 7.2 0.2 5.1 6 0 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NADH-UOR_E PF16514.5 XP_667814.1 - 1 9.7 3.1 92 3.5 0.0 3.9 3 0 0 3 3 3 0 putative NADH-ubiquinone oxidoreductase chain E HALZ PF02183.18 XP_667815.1 - 0.25 11.6 9.1 2.4 8.4 0.9 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4793 PF16041.5 XP_667815.1 - 1 9.5 6.5 2.7 8.2 6.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) Sec23_trunk PF04811.15 XP_667816.1 - 1.4e-16 60.9 0.0 1.4e-16 60.9 0.0 2.1 3 0 0 3 3 3 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 XP_667816.1 - 1.3e-14 54.7 0.0 5.9e-14 52.6 0.0 2.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 XP_667816.1 - 1.8e-11 43.9 8.0 5.7e-11 42.3 8.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 XP_667816.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 2.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 XP_667816.1 - 0.024 14.5 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 0 Gelsolin repeat LsmAD PF06741.13 XP_667816.1 - 0.22 12.1 3.4 0.51 10.9 3.4 1.6 1 0 0 1 1 1 0 LsmAD domain DUF3464 PF11947.8 XP_667816.1 - 6.9 6.4 7.1 30 4.3 7.1 2.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF1744 PF08490.12 XP_667817.1 - 5.1e-23 81.3 10.2 1.5e-12 46.8 1.1 4.1 3 1 0 3 3 3 3 Domain of unknown function (DUF1744) BUD22 PF09073.10 XP_667817.1 - 0.0033 16.8 12.4 0.0033 16.8 12.4 3.4 3 0 0 3 3 3 1 BUD22 Serglycin PF04360.12 XP_667817.1 - 0.02 14.8 2.9 0.028 14.4 0.1 2.6 2 0 0 2 2 2 0 Serglycin NARP1 PF12569.8 XP_667817.1 - 0.41 9.5 29.1 1.7 7.5 11.1 2.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 PspB PF06667.12 XP_667819.1 - 0.033 14.3 0.7 0.052 13.6 0.7 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF809 PF05663.11 XP_667819.1 - 0.04 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Myc_target_1 PF15179.6 XP_667819.1 - 0.067 13.1 0.1 0.078 12.9 0.1 1.1 1 0 0 1 1 1 0 Myc target protein 1 Insulin_TMD PF17870.1 XP_667819.1 - 0.082 13.0 2.7 0.15 12.2 2.7 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vpu PF00558.19 XP_667819.1 - 0.17 11.7 3.2 0.24 11.2 3.2 1.3 1 0 0 1 1 1 0 Vpu protein DnaJ PF00226.31 XP_667820.1 - 1.7e-24 85.7 1.2 3.5e-24 84.7 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 XP_667820.1 - 1.4e-14 54.3 0.4 1.4e-14 54.3 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) PRAI PF00697.22 XP_667820.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SR-25 PF10500.9 XP_667820.1 - 0.084 12.5 10.8 0.15 11.7 10.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 XP_667820.1 - 0.3 9.6 10.6 0.37 9.3 10.6 1.2 1 0 0 1 1 1 0 Macoilin family YfdX PF10938.8 XP_667820.1 - 0.44 10.5 0.0 0.44 10.5 0.0 2.0 3 0 0 3 3 3 0 YfdX protein Zip PF02535.22 XP_667820.1 - 0.89 8.7 6.7 0.18 11.0 3.9 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.14 XP_667820.1 - 3.4 7.0 16.1 6.9 6.0 16.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NAC PF01849.18 XP_667821.1 - 6.9e-16 58.0 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 XP_667821.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Spc24 PF08286.11 XP_667821.1 - 0.033 14.4 3.0 3.4 7.9 1.8 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YqfQ PF14181.6 XP_667821.1 - 0.26 11.5 5.9 1.4 9.1 1.8 2.2 2 0 0 2 2 2 0 YqfQ-like protein 5_nucleotid_C PF02872.18 XP_667822.1 - 9.5e-34 116.9 0.0 2.5e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 XP_667822.1 - 3.2e-10 40.8 0.2 5.3e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DTW PF03942.15 XP_667823.1 - 6.3e-25 88.1 0.1 9e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 DTW domain 4HBT PF03061.22 XP_667824.1 - 9.2e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily BPL_N PF09825.9 XP_667825.1 - 1.1e-08 34.6 0.1 2.2e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal Ipi1_N PF12333.8 XP_667826.1 - 0.1 13.2 0.1 0.52 10.9 0.0 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation GrpE PF01025.19 XP_667827.1 - 6.3e-48 162.6 3.1 7.9e-48 162.3 3.1 1.1 1 0 0 1 1 1 1 GrpE DsrC PF04358.13 XP_667827.1 - 0.02 15.4 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 DsrC like protein Dna2 PF08696.11 XP_667827.1 - 0.072 12.9 1.1 0.12 12.2 0.3 1.6 1 1 1 2 2 2 0 DNA replication factor Dna2 PikAIV_N PF18605.1 XP_667827.1 - 0.15 11.7 2.8 0.28 10.8 2.8 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DnaJ PF00226.31 XP_667828.1 - 1.8e-07 31.2 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 XP_667828.1 - 1.2e-05 25.3 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 XP_667829.1 - 3.1e-19 68.9 1.0 7.6e-19 67.6 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TFIIB PF00382.19 XP_667830.1 - 1.4e-23 82.7 0.3 6.4e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 XP_667830.1 - 4.5e-17 62.2 3.7 4.5e-17 62.2 3.7 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 XP_667830.1 - 3.4e-11 42.5 1.5 1e-10 40.9 1.5 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 XP_667830.1 - 0.0059 16.3 1.0 0.013 15.1 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 XP_667830.1 - 0.07 13.2 1.2 0.17 11.9 1.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 XP_667830.1 - 1 8.8 4.8 7.1 6.2 4.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain GLTP PF08718.11 XP_667831.1 - 1.3e-22 80.7 0.1 2.4e-22 79.8 0.1 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Methyltr_RsmB-F PF01189.17 XP_667832.1 - 2e-32 112.5 0.0 3.4e-30 105.2 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 XP_667832.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4193 PF13834.6 XP_667832.1 - 0.092 13.3 1.1 0.56 10.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Transketolase_C PF02780.20 XP_667832.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain 2-oxogl_dehyd_N PF16078.5 XP_667833.1 - 0.1 12.2 0.8 0.29 10.7 0.2 2.1 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus SbmA_BacA PF05992.12 XP_667834.1 - 1.9e-62 211.5 11.1 2.2e-62 211.3 11.1 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family DUF489 PF04356.12 XP_667835.1 - 0.034 14.2 0.2 0.052 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) STAG PF08514.11 XP_667836.1 - 0.0011 18.8 0.8 0.0057 16.6 0.0 2.8 2 0 0 2 2 2 1 STAG domain YqgC PF17430.2 XP_667838.1 - 0.32 11.1 1.7 0.88 9.7 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized YqgC-like Bax1-I PF01027.20 XP_667839.1 - 1.5e-29 103.4 30.0 1.8e-29 103.1 30.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2613 PF11021.8 XP_667839.1 - 0.24 11.6 1.9 1.8 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) tRNA-synt_1b PF00579.25 XP_667840.1 - 8.2e-55 186.2 0.0 1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Folate_rec PF03024.14 XP_667841.1 - 2.5e-23 82.8 11.1 3.3e-23 82.4 11.1 1.2 1 0 0 1 1 1 1 Folate receptor family DUF2013 PF09431.10 XP_667842.1 - 1e-05 25.7 0.1 1.8e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RRM_1 PF00076.22 XP_667843.1 - 1.7e-75 248.8 0.1 6.8e-19 67.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 XP_667843.1 - 3.6e-26 91.1 0.9 8e-26 90.0 0.9 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 XP_667843.1 - 4.5e-06 26.3 0.0 0.0069 16.0 0.0 4.1 2 1 2 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 XP_667843.1 - 0.00097 19.0 0.0 0.14 12.0 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 XP_667843.1 - 0.0012 18.9 0.0 14 5.9 0.0 4.6 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 XP_667843.1 - 0.0037 17.2 0.1 7.2 6.7 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 XP_667843.1 - 0.013 15.5 0.1 7.7 6.6 0.0 3.6 3 0 0 3 3 3 0 RNA binding motif CDC45 PF02724.14 XP_667843.1 - 0.79 7.9 7.7 1.1 7.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein EFTUD2 PF16004.5 XP_667843.1 - 0.8 10.3 6.6 2.5 8.7 6.6 1.8 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Presenilin PF01080.17 XP_667843.1 - 0.81 8.4 5.8 1.3 7.7 5.8 1.2 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 XP_667846.1 - 1.3e-11 44.8 0.5 0.015 16.1 0.0 5.5 4 1 1 5 5 5 3 WD domain, G-beta repeat Spore_YpjB PF09577.10 XP_667846.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) UCH PF00443.29 XP_667847.1 - 1.7e-37 129.3 14.0 1.7e-37 129.3 14.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 XP_667847.1 - 9.6e-15 55.0 9.5 1.4e-13 51.1 9.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 XP_667847.1 - 1.4e-13 50.3 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger zf-UBP PF02148.19 XP_667847.1 - 4.8e-11 42.8 0.1 2.8e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 XP_667847.1 - 0.00011 22.0 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 XP_667847.1 - 0.0018 18.1 0.5 0.0048 16.7 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain Hormone_recep PF00104.30 XP_667847.1 - 0.021 14.4 1.8 0.056 13.0 0.7 2.3 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor RecX PF02631.16 XP_667847.1 - 0.068 13.6 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 RecX family DHHC PF01529.20 XP_667848.1 - 1.5e-35 122.2 4.0 1.5e-35 122.2 4.0 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Svf1_C PF17187.4 XP_667849.1 - 0.029 14.2 1.5 0.078 12.8 1.5 1.8 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain Myb_DNA-binding PF00249.31 XP_667851.1 - 1.1e-07 32.0 0.2 2.8e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 XP_667851.1 - 8e-05 22.8 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HEPN_Swt1 PF18731.1 XP_667852.1 - 0.61 10.4 4.0 10 6.5 0.1 3.3 2 1 1 3 3 3 0 Swt1-like HEPN Stathmin PF00836.19 XP_667852.1 - 1.5 8.8 6.3 1.3 9.0 0.7 3.0 3 0 0 3 3 3 0 Stathmin family PRA1 PF03208.19 XP_667852.1 - 5.8 6.5 16.3 1.8 8.2 12.9 1.8 2 0 0 2 2 2 0 PRA1 family protein RRM_1 PF00076.22 XP_667853.1 - 7.5e-37 125.0 0.9 1.2e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_667853.1 - 1.5e-06 27.8 0.7 0.0071 15.9 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_667853.1 - 0.015 15.4 0.1 2.1 8.5 0.1 2.5 2 1 0 2 2 2 0 RNA recognition motif DUF4523 PF15023.6 XP_667853.1 - 0.045 13.6 0.0 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ank_4 PF13637.6 XP_667854.1 - 1.6e-39 133.8 0.9 7e-11 42.4 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 XP_667854.1 - 8.7e-35 119.2 0.1 5.4e-12 46.1 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 XP_667854.1 - 2e-30 101.4 0.7 0.00018 21.7 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 XP_667854.1 - 9.4e-30 101.7 0.4 2.8e-05 24.4 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 XP_667854.1 - 6.6e-28 96.4 1.4 3e-08 33.8 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) RNA_GG_bind PF10258.9 XP_667854.1 - 2.3e-24 85.2 0.3 4.4e-24 84.3 0.3 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF3447 PF11929.8 XP_667854.1 - 0.00095 19.1 1.3 1.9 8.5 0.0 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) YjzC PF14168.6 XP_667854.1 - 0.21 12.0 0.7 3.6 8.0 0.2 2.5 1 1 1 2 2 2 0 YjzC-like protein DUF3384 PF11864.8 XP_667856.1 - 0.052 12.4 0.3 0.16 10.9 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3384) CTD_bind PF04818.13 XP_667857.1 - 9.7e-07 29.5 0.0 7.6e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf-C2H2 PF00096.26 XP_667857.1 - 0.63 10.6 8.4 0.18 12.3 1.8 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type UPF0139 PF03669.13 XP_667858.1 - 0.016 15.1 1.5 0.019 14.9 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) VID27 PF08553.10 XP_667860.1 - 4.2e-55 187.2 0.7 5.9e-55 186.8 0.1 1.5 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain CDC73_C PF05179.14 XP_667861.1 - 9.6e-42 142.3 1.2 2.8e-41 140.8 1.2 1.8 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF5101 PF17031.5 XP_667861.1 - 0.52 10.4 6.6 4 7.6 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5101) ISP1_C PF18161.1 XP_667862.1 - 5.3e-26 90.7 0.3 5.3e-26 90.7 0.3 3.3 3 1 1 4 4 4 1 ISP1 C-terminal ISP3_C PF18045.1 XP_667862.1 - 1.4e-22 79.6 0.2 3.7e-22 78.3 0.2 1.7 1 0 0 1 1 1 1 ISP3 C-terminal Nop52 PF05997.12 XP_667863.1 - 5.8e-44 150.5 7.5 1e-43 149.7 6.1 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 RabGAP-TBC PF00566.18 XP_667864.1 - 1.2e-60 204.8 2.1 2.2e-60 204.0 2.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BatD PF13584.6 XP_667865.1 - 0.041 12.7 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance SCF PF02404.15 XP_667865.1 - 0.044 13.1 0.4 0.053 12.8 0.4 1.1 1 0 0 1 1 1 0 Stem cell factor DUF3834 PF12916.7 XP_667865.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) RIFIN PF02009.16 XP_667865.1 - 0.15 11.9 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 Rifin EGL-1 PF11430.8 XP_667865.1 - 0.23 11.4 2.4 0.47 10.4 2.4 1.5 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 ThiF PF00899.21 XP_667866.1 - 1e-43 149.5 0.2 1.4e-43 149.0 0.2 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 XP_667866.1 - 0.00085 19.6 1.4 0.0039 17.4 1.4 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 XP_667866.1 - 0.013 15.8 0.5 0.057 13.7 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 XP_667866.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GAPT PF11770.8 XP_667866.1 - 0.042 13.7 1.8 0.086 12.7 1.8 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Shikimate_DH PF01488.20 XP_667866.1 - 0.047 13.7 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 XP_667866.1 - 0.062 12.9 1.1 0.12 11.9 1.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4731 PF15875.5 XP_667866.1 - 0.07 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) PglD_N PF17836.1 XP_667866.1 - 0.075 13.7 0.1 0.22 12.2 0.1 1.9 1 0 0 1 1 1 0 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 XP_667866.1 - 0.082 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNase_PH PF01138.21 XP_667867.1 - 1.2e-17 64.6 0.0 2.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NDK PF00334.19 XP_667868.1 - 5.4e-53 178.6 0.0 6.1e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ORC2 PF04084.14 XP_667869.1 - 2.9e-41 141.5 6.1 4.5e-41 140.9 6.1 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Exo_endo_phos PF03372.23 XP_667870.1 - 3.4e-23 82.4 0.0 1.3e-22 80.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF676 PF05057.14 XP_667871.1 - 9.5e-24 84.1 0.1 2.9e-23 82.5 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 XP_667871.1 - 9.9e-05 22.3 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Palmitoyl protein thioesterase KIP1 PF07765.12 XP_667871.1 - 0.088 12.9 0.4 0.21 11.7 0.4 1.7 1 0 0 1 1 1 0 KIP1-like protein Phage_TTP_1 PF04630.12 XP_667872.1 - 0.014 14.7 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Phage tail tube protein Myb_DNA-bind_3 PF12776.7 XP_667872.1 - 0.034 15.1 1.8 0.045 14.7 0.5 1.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Fzo_mitofusin PF04799.13 XP_667872.1 - 0.32 10.5 6.4 0.59 9.7 6.2 1.4 1 1 0 1 1 1 0 fzo-like conserved region YfhO PF09586.10 XP_667872.1 - 2.7 6.1 7.9 1.2 7.3 6.0 1.4 1 1 1 2 2 2 0 Bacterial membrane protein YfhO A_deaminase PF00962.22 XP_667873.1 - 1.6e-80 270.9 0.0 2.1e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1965 PF09248.10 XP_667873.1 - 0.012 15.4 1.3 0.024 14.4 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) DUF2857 PF11198.8 XP_667873.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) DUF1474 PF07342.11 XP_667873.1 - 0.32 11.5 2.5 0.41 11.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) TPR_1 PF00515.28 XP_667874.1 - 9.9e-15 53.7 0.2 4.2e-05 23.2 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 XP_667874.1 - 1.9e-12 46.3 0.9 0.0046 17.0 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 XP_667874.1 - 1.4e-08 35.1 0.9 0.00025 21.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 XP_667874.1 - 3.3e-08 33.1 0.0 0.00031 20.4 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 XP_667874.1 - 2.7e-07 31.1 4.0 0.00011 22.7 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_667874.1 - 3.7e-06 26.7 1.2 1.4 9.3 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 XP_667874.1 - 7.3e-06 26.0 0.3 0.27 11.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_667874.1 - 0.0011 19.2 0.9 0.0034 17.6 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 XP_667874.1 - 0.0015 18.8 2.0 0.091 13.1 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 XP_667874.1 - 0.014 15.3 0.8 7.8 6.8 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 XP_667874.1 - 0.016 15.3 0.0 0.053 13.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 XP_667874.1 - 0.15 12.9 8.0 0.3 12.0 0.3 4.0 3 1 2 5 5 3 0 Tetratricopeptide repeat PGM_PMM_III PF02880.16 XP_667875.1 - 2.4e-27 95.4 0.0 5.5e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 XP_667875.1 - 8.2e-26 90.4 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 XP_667875.1 - 3.3e-13 50.1 0.0 1e-12 48.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 XP_667875.1 - 6.7e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Mucin PF01456.17 XP_667876.1 - 0.00015 21.8 34.9 0.00015 21.8 34.9 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein RMI1_N PF08585.12 XP_667877.1 - 4.2e-08 33.2 0.8 4.2e-08 33.2 0.8 3.0 2 2 0 2 2 2 1 RecQ mediated genome instability protein DUF4407 PF14362.6 XP_667877.1 - 0.076 12.4 1.2 0.16 11.3 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 XP_667877.1 - 0.14 11.5 0.5 0.25 10.7 0.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 ACR_tran PF00873.19 XP_667877.1 - 0.51 7.9 3.3 0.66 7.6 3.3 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family LMBR1 PF04791.16 XP_667877.1 - 5.7 5.7 5.2 7 5.4 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_C1 PF00112.23 XP_667879.1 - 1.4e-30 107.0 20.5 6.1e-21 75.5 1.3 3.2 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.11 XP_667879.1 - 6.8e-13 48.9 4.9 1.2e-11 45.0 4.9 2.7 1 1 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 XP_667879.1 - 0.00015 20.7 0.6 0.00036 19.4 0.6 1.5 1 0 0 1 1 1 1 Peptidase C1-like family DUF4746 PF15928.5 XP_667879.1 - 0.0025 17.3 13.2 0.0046 16.4 13.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Nop14 PF04147.12 XP_667879.1 - 0.19 9.9 26.9 0.29 9.3 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 XP_667879.1 - 0.23 9.7 17.1 0.32 9.2 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 XP_667879.1 - 0.41 10.6 11.1 0.74 9.8 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LAP1C PF05609.12 XP_667879.1 - 0.53 9.3 16.6 19 4.2 16.2 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) PBP_sp32 PF07222.12 XP_667879.1 - 0.99 8.8 17.3 2.6 7.4 17.3 1.7 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Spore_coat_CotO PF14153.6 XP_667879.1 - 1 9.2 20.0 2.3 8.1 20.0 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 XP_667879.1 - 3.3 6.4 17.9 5.3 5.7 17.9 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 XP_667879.1 - 4.7 5.6 13.5 7.3 5.0 13.5 1.2 1 0 0 1 1 1 0 Macoilin family PPL5 PF18168.1 XP_667879.1 - 9 5.5 14.4 15 4.7 14.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 HSP70 PF00012.20 XP_667880.1 - 4.3e-55 187.0 0.2 1.8e-44 152.0 0.2 3.0 2 1 0 2 2 2 2 Hsp70 protein Pan3_PK PF18101.1 XP_667881.1 - 3.5e-47 159.8 0.1 5.5e-47 159.2 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 XP_667881.1 - 5.4e-05 22.7 0.0 0.00011 21.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Serglycin PF04360.12 XP_667881.1 - 0.92 9.5 0.0 0.92 9.5 0.0 4.0 4 1 0 4 4 4 0 Serglycin FH2 PF02181.23 XP_667882.1 - 0.0032 16.6 2.4 0.0049 16.1 2.4 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Phage_int_SAM_6 PF18644.1 XP_667882.1 - 0.0092 16.0 0.2 0.019 15.0 0.2 1.6 1 0 0 1 1 1 1 Phage integrase SAM-like domain COG2 PF06148.11 XP_667882.1 - 0.036 14.1 3.6 0.049 13.7 1.5 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YojJ PF10372.9 XP_667882.1 - 0.17 12.0 1.3 0.36 10.9 0.3 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Spc7 PF08317.11 XP_667882.1 - 0.32 9.8 8.7 0.52 9.1 8.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Microvir_H PF04687.12 XP_667882.1 - 0.66 9.3 3.5 0.69 9.2 2.0 1.7 2 0 0 2 2 2 0 Microvirus H protein (pilot protein) KxDL PF10241.9 XP_667882.1 - 0.88 9.9 5.1 0.81 10.0 1.3 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF615 PF04751.14 XP_667882.1 - 1.6 8.7 9.8 1.9 8.4 8.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF615) SlyX PF04102.12 XP_667882.1 - 1.9 9.2 8.7 11 6.7 0.3 2.4 2 0 0 2 2 2 0 SlyX SWIRM-assoc_1 PF16495.5 XP_667883.1 - 0.0053 16.7 2.8 0.0053 16.7 2.8 1.4 2 0 0 2 2 2 1 SWIRM-associated region 1 DUF4600 PF15372.6 XP_667883.1 - 0.029 14.8 3.3 0.036 14.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) GIT_CC PF16559.5 XP_667883.1 - 0.1 12.5 3.9 0.31 10.9 1.2 2.3 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 XP_667883.1 - 0.38 11.2 7.4 0.06 13.8 2.7 1.8 2 0 0 2 2 2 0 Cell division protein ZapB FIN1 PF17300.2 XP_667883.1 - 0.41 10.1 4.6 0.5 9.8 4.6 1.0 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 MFS_1 PF07690.16 XP_667884.1 - 1.6e-06 27.3 8.5 2.1e-06 26.9 8.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2304 PF10066.9 XP_667884.1 - 7.9 6.7 11.3 2.2 8.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DnaJ PF00226.31 XP_667885.1 - 2.2e-29 101.3 3.4 3.4e-29 100.8 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain NCOA_u2 PF16665.5 XP_667885.1 - 0.84 9.9 11.7 0.079 13.3 6.7 1.7 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein Helicase_C_2 PF13307.6 XP_667886.1 - 2e-54 184.3 1.0 1.3e-53 181.7 0.0 2.7 3 1 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 XP_667886.1 - 4.7e-41 140.3 4.6 3e-39 134.4 4.6 2.7 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 XP_667886.1 - 2.8e-05 24.2 6.1 0.00099 19.1 0.1 3.6 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_667886.1 - 4.1e-05 23.4 2.9 0.039 13.7 0.1 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase AAA_22 PF13401.6 XP_667886.1 - 0.013 15.8 3.0 3 8.1 0.2 3.0 3 0 0 3 3 3 0 AAA domain Exog_C PF18026.1 XP_667886.1 - 0.029 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain FtsJ PF01728.19 XP_667888.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PIN_8 PF18476.1 XP_667888.1 - 0.24 11.2 2.9 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 PIN like domain FKBP_C PF00254.28 XP_667889.1 - 1.4e-16 60.6 0.0 3.1e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 XP_667889.1 - 1.3e-07 32.4 0.0 2.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase APC_u14 PF16635.5 XP_667889.1 - 0.011 16.3 0.4 0.023 15.2 0.4 1.5 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr NTP_transf_2 PF01909.23 XP_667890.1 - 0.00026 21.2 0.0 0.00083 19.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 XP_667890.1 - 0.0015 18.6 0.1 0.0046 17.0 0.1 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Tai4 PF16695.5 XP_667890.1 - 0.07 13.7 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein UPAR_LY6_2 PF16975.5 XP_667890.1 - 0.077 13.2 2.2 0.95 9.7 0.1 2.6 2 0 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 TPX2_importin PF12214.8 XP_667891.1 - 0.06 13.5 25.8 0.11 12.7 0.3 4.7 2 2 1 4 4 4 0 Cell cycle regulated microtubule associated protein DUF573 PF04504.14 XP_667891.1 - 0.17 12.5 4.0 0.15 12.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF573 SDA1 PF05285.12 XP_667893.1 - 0.062 12.7 13.3 0.07 12.5 13.3 1.1 1 0 0 1 1 1 0 SDA1 SRTM1 PF15872.5 XP_667893.1 - 0.066 13.4 0.2 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Nop14 PF04147.12 XP_667893.1 - 0.33 9.1 13.3 0.41 8.8 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 XP_667894.1 - 7.9e-15 54.4 0.0 1.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OTU PF02338.19 XP_667895.1 - 1.7e-15 57.6 0.1 6.2e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 XP_667895.1 - 4.1e-09 36.3 3.3 5.4e-06 26.0 1.1 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain SLX9 PF15341.6 XP_667896.1 - 0.063 13.7 8.1 0.16 12.4 2.3 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 RCC1 PF00415.18 XP_667897.1 - 6.7e-77 253.9 20.6 8.8e-15 55.1 0.4 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 XP_667897.1 - 1.6e-36 123.4 43.0 5.5e-08 32.4 0.3 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 XP_667897.1 - 0.0046 16.8 2.9 3.5 7.5 0.0 4.2 4 1 1 5 5 5 2 Peptidase family C25, C terminal ig-like domain Hira PF07569.11 XP_667897.1 - 0.022 14.5 0.8 8.4 6.0 0.1 3.9 4 0 0 4 4 4 0 TUP1-like enhancer of split Cep57_CLD_2 PF14197.6 XP_667897.1 - 0.22 11.6 3.8 0.48 10.6 3.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SNAP-25 PF00835.19 XP_667898.1 - 0.0025 18.1 0.2 0.0081 16.4 0.1 1.9 2 0 0 2 2 2 1 SNAP-25 family RTC_insert PF05189.13 XP_667899.1 - 3.3e-19 69.3 0.0 6.9e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 XP_667899.1 - 8.4e-15 54.6 0.0 9.7e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase BNIP2 PF12496.8 XP_667899.1 - 0.1 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Carboxyl_trans PF01039.22 XP_667901.1 - 3.6e-146 487.7 0.0 4.8e-146 487.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 XP_667901.1 - 1.2e-47 162.1 1.0 2.8e-47 160.9 1.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 XP_667901.1 - 3.6e-37 128.0 9.3 5.9e-18 64.5 3.1 5.4 4 1 0 4 4 4 4 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 XP_667901.1 - 1.4e-28 99.7 0.0 4.1e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 XP_667901.1 - 1.8e-18 66.6 0.0 5.9e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 XP_667901.1 - 7.6e-09 35.3 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 XP_667901.1 - 3.8e-07 29.8 0.3 1.3e-06 28.1 0.3 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 XP_667901.1 - 2.8e-06 27.5 0.5 9.5e-06 25.7 0.5 2.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 XP_667901.1 - 0.00011 21.9 0.2 0.00027 20.6 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 XP_667901.1 - 0.013 15.1 0.7 0.038 13.6 0.7 1.8 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 XP_667901.1 - 0.11 12.3 0.2 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 XP_667901.1 - 0.45 11.3 1.6 54 4.6 0.0 3.4 4 0 0 4 4 3 0 HlyD family secretion protein MEF2_binding PF09047.10 XP_667902.1 - 0.094 12.6 1.6 8.9 6.3 0.6 3.0 2 0 0 2 2 2 0 MEF2 binding NuA4 PF09340.10 XP_667902.1 - 1.3 9.0 5.7 0.2 11.6 1.0 2.0 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Nop25 PF09805.9 XP_667903.1 - 4.9e-07 30.3 11.6 5.7e-07 30.1 11.6 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) SYCE1 PF15233.6 XP_667903.1 - 0.034 14.2 3.7 0.038 14.1 3.7 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 CCDC53 PF10152.9 XP_667904.1 - 1.2 9.5 7.4 1.6 9.1 2.8 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex zf-CCHC_2 PF13696.6 XP_667905.1 - 1.4e-08 34.4 5.4 2.6e-08 33.5 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_UBOX PF13445.6 XP_667905.1 - 0.0011 19.0 3.9 0.0028 17.6 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 XP_667905.1 - 0.0053 16.6 5.1 0.0053 16.6 5.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_667905.1 - 0.006 16.4 7.6 0.006 16.4 7.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_667905.1 - 0.0066 16.8 8.8 0.0066 16.8 8.8 1.9 2 0 0 2 2 2 1 Ring finger domain DWNN PF08783.11 XP_667905.1 - 0.017 15.4 0.2 0.048 13.9 0.2 1.9 1 0 0 1 1 1 0 DWNN domain zf-C3HC4_4 PF15227.6 XP_667905.1 - 0.018 15.2 8.5 0.12 12.5 8.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-CCHC PF00098.23 XP_667905.1 - 0.25 11.5 3.9 0.6 10.3 3.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Rubredoxin PF00301.20 XP_667905.1 - 0.57 10.3 3.6 16 5.6 0.0 3.9 3 1 0 3 3 3 0 Rubredoxin FANCL_C PF11793.8 XP_667905.1 - 0.58 10.4 5.6 1.7 8.9 5.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 XP_667905.1 - 1.2 9.2 15.6 0.17 11.9 9.2 2.3 2 0 0 2 2 2 0 zinc-RING finger domain ER PF01133.17 XP_667906.1 - 0.015 15.3 1.0 0.061 13.3 1.0 2.0 1 1 0 1 1 1 0 Enhancer of rudimentary Aa_trans PF01490.18 XP_667907.1 - 6.2e-52 176.7 43.5 7.6e-52 176.4 43.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 XP_667907.1 - 1e-05 24.8 23.1 1e-05 24.8 23.1 2.0 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF4844 PF16133.5 XP_667908.1 - 0.41 11.2 6.2 0.2 12.2 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) DUF1126 PF06565.12 XP_667909.1 - 0.023 14.5 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 DUF1126 PH-like domain DnaJ_C PF01556.18 XP_667910.1 - 1.6e-38 132.1 1.4 3e-38 131.2 1.4 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 XP_667910.1 - 2.5e-24 85.1 1.2 4.9e-24 84.2 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 XP_667910.1 - 7.1e-14 51.9 15.4 1.2e-13 51.2 15.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 XP_667910.1 - 1.5 8.8 12.7 0.29 11.1 3.4 2.8 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein SNARE PF05739.19 XP_667911.1 - 0.28 11.2 3.4 0.27 11.2 1.6 1.9 2 0 0 2 2 2 0 SNARE domain EMP24_GP25L PF01105.24 XP_667911.1 - 0.98 9.3 4.4 1.7 8.6 4.4 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CRAL_TRIO PF00650.20 XP_667912.1 - 4.6e-30 104.4 0.1 5.2e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 XP_667912.1 - 8.6e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IQ PF00612.27 XP_667912.1 - 0.00097 18.7 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_head PF00063.21 XP_667914.1 - 1.7e-182 608.3 13.9 1.7e-182 608.3 13.9 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) RCC1 PF00415.18 XP_667914.1 - 8.5e-24 83.9 0.1 3.6e-10 40.3 0.1 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 XP_667914.1 - 4.2e-19 67.8 5.1 1.1e-10 41.0 0.4 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 XP_667914.1 - 2.2e-08 33.2 38.0 0.00029 20.4 0.6 7.5 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_16 PF13191.6 XP_667914.1 - 0.01 16.3 0.1 0.035 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 XP_667914.1 - 0.046 13.8 0.2 0.15 12.2 0.2 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 XP_667914.1 - 0.084 13.1 0.0 0.42 10.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 XP_667916.1 - 7.7e-51 171.9 0.0 8.9e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 XP_667916.1 - 8.2e-31 106.7 0.0 1.4e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 XP_667916.1 - 1.9e-14 53.5 0.0 2.3e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 XP_667916.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 XP_667916.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 XP_667916.1 - 0.0027 17.3 0.1 0.0085 15.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 XP_667916.1 - 0.011 15.2 0.0 0.032 13.6 0.0 1.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 XP_667916.1 - 0.033 13.6 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 XP_667916.1 - 0.076 13.4 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 XP_667916.1 - 0.1 12.8 0.1 0.41 10.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain CS PF04969.16 XP_667917.1 - 4.6e-15 56.4 1.6 9.4e-15 55.4 1.6 1.6 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 XP_667917.1 - 1.4e-14 53.8 0.5 3.4e-14 52.6 0.5 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. DUF1682 PF07946.14 XP_667917.1 - 0.12 11.5 7.5 0.21 10.8 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 XP_667917.1 - 0.52 9.0 1.5 0.66 8.7 1.5 1.1 1 0 0 1 1 1 0 Presenilin MscS_TM PF12794.7 XP_667917.1 - 6.4 5.5 5.4 8.9 5.1 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 WD40 PF00400.32 XP_667918.1 - 1.9e-19 69.6 1.4 3.6e-07 30.8 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 XP_667918.1 - 1.8e-16 59.7 0.2 4.2e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Type of WD40 repeat DUF1899 PF08953.11 XP_667918.1 - 1e-15 57.3 0.1 2e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 XP_667918.1 - 4.5e-07 30.1 0.4 0.0001 22.5 0.2 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 XP_667918.1 - 0.0082 15.1 0.7 3 6.7 0.3 2.6 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PSII_BNR PF14870.6 XP_667918.1 - 0.011 15.0 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 PKcGMP_CC PF16808.5 XP_667918.1 - 0.042 13.7 0.4 0.097 12.5 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_GP20 PF06810.11 XP_667918.1 - 0.05 13.4 1.8 0.083 12.7 1.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1115 PF06544.12 XP_667919.1 - 7.9e-12 45.5 0.1 1.5e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 XP_667919.1 - 0.013 15.7 0.1 0.047 14.0 0.1 2.0 1 1 0 1 1 1 0 RWD domain Shugoshin_N PF07558.11 XP_667919.1 - 1.2 9.0 5.0 2 8.4 0.3 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Metallophos PF00149.28 XP_667920.1 - 1.3e-17 65.0 1.3 2.4e-17 64.1 1.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RIO1 PF01163.22 XP_667920.1 - 0.098 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Glycos_transf_2 PF00535.26 XP_667922.1 - 1.5e-09 37.9 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 XP_667922.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 XP_667922.1 - 0.033 13.7 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 EF1G PF00647.19 XP_667923.1 - 3.7e-36 123.4 0.8 6.1e-36 122.7 0.2 1.6 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 XP_667923.1 - 1.8e-08 34.5 0.0 3.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 XP_667923.1 - 2.1e-07 31.1 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 XP_667923.1 - 0.016 15.3 0.0 0.056 13.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_L6e PF01159.19 XP_667924.1 - 1.1e-33 116.0 0.9 1.6e-33 115.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Phage_attach PF05354.11 XP_667924.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 1 0 1 1 1 0 Phage Head-Tail Attachment DUF3496 PF12001.8 XP_667924.1 - 0.035 14.5 0.2 0.064 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DSPn PF14671.6 XP_667925.1 - 1.3e-44 152.1 0.6 3.1e-44 150.9 0.3 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 XP_667925.1 - 1.5e-10 41.0 0.2 1.2e-08 34.8 0.0 3.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 XP_667925.1 - 0.00023 21.3 0.1 0.00069 19.8 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 XP_667925.1 - 0.0015 18.2 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RRM_1 PF00076.22 XP_667926.1 - 8.9e-32 108.7 1.6 3.8e-17 61.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HigB_toxin PF09907.9 XP_667926.1 - 0.023 14.9 0.2 0.098 12.9 0.2 2.0 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system RRM_7 PF16367.5 XP_667926.1 - 0.042 14.0 0.0 1.3 9.2 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif DUF5602 PF18197.1 XP_667926.1 - 0.2 12.1 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5602) AF-4 PF05110.13 XP_667928.1 - 0.06 11.4 30.4 0.095 10.8 30.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PSDC PF12588.8 XP_667928.1 - 0.096 12.7 0.1 16 5.4 0.0 3.2 3 0 0 3 3 3 0 Phophatidylserine decarboxylase RNase_H2_suC PF08615.11 XP_667928.1 - 0.72 10.0 5.1 1 9.5 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) YjbH PF06082.11 XP_667928.1 - 8.5 5.1 10.4 13 4.5 10.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Tachystatin_B PF11478.8 XP_667930.1 - 0.0098 15.8 6.2 0.018 14.9 6.2 1.5 1 0 0 1 1 1 1 Antimicrobial chitin binding protein tachystatin B Metallophos PF00149.28 XP_667931.1 - 8.9e-15 55.7 0.7 7.2e-14 52.8 0.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aa_trans PF01490.18 XP_667932.1 - 2.8e-60 204.1 39.2 3.6e-60 203.8 39.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 XP_667932.1 - 2e-06 27.1 20.0 2e-06 27.1 20.0 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4233 PF14017.6 XP_667932.1 - 8.6 6.8 18.3 5.3 7.4 0.6 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF4233) APC_r PF05923.12 XP_667933.1 - 0.32 10.8 2.2 1.1 9.1 2.2 2.0 1 0 0 1 1 1 0 APC repeat Chordopox_A30L PF06015.12 XP_667934.1 - 0.095 12.5 2.2 0.8 9.6 1.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus A30L protein DUF543 PF04418.12 XP_667935.1 - 2.5 8.1 5.3 5.6 7.0 5.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF543) TFIIIC_sub6 PF10419.9 XP_667936.1 - 0.0056 16.5 0.4 0.0075 16.1 0.4 1.3 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain YL1 PF05764.13 XP_667937.1 - 4.1e-30 105.7 32.2 4.1e-30 105.7 32.2 2.2 1 1 1 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 XP_667937.1 - 2.1e-11 43.3 0.6 2.7e-10 39.8 0.2 2.4 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PAN_4 PF14295.6 XP_667939.1 - 0.00014 21.7 0.3 0.00041 20.2 0.3 1.9 1 0 0 1 1 1 1 PAN domain GAGA_bind PF06217.12 XP_667942.1 - 2.2 8.5 23.1 0.99 9.6 4.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.17 XP_667942.1 - 7.3 6.7 18.4 0.29 11.3 0.3 2.2 2 0 0 2 2 2 0 DDHD domain DSHCT PF08148.12 XP_667944.1 - 9.6e-46 155.4 0.0 2e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 XP_667944.1 - 6.6e-18 65.6 11.4 6.7e-18 65.6 7.9 2.9 2 1 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 XP_667944.1 - 6.9e-16 58.5 0.1 2.2e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_667944.1 - 3.9e-05 24.0 2.4 0.00025 21.3 0.0 3.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Sushi PF00084.20 XP_667945.1 - 1.7e-05 25.4 1.3 3.7e-05 24.2 1.3 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) ZYG-11_interact PF05884.12 XP_667945.1 - 1.9 7.8 3.9 4.4 6.6 3.9 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 Troponin PF00992.20 XP_667946.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Troponin DUF2701 PF10857.8 XP_667947.1 - 1.3 9.1 5.7 0.46 10.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) MFS_2 PF13347.6 XP_667948.1 - 0.0036 15.9 0.9 0.0036 15.9 0.9 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein TssO PF17561.2 XP_667948.1 - 0.0061 16.7 1.5 0.0061 16.7 1.5 1.7 1 1 1 2 2 2 1 Type VI secretion system, TssO DUF4131 PF13567.6 XP_667948.1 - 0.043 13.5 2.6 0.048 13.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PIG-Y PF15159.6 XP_667948.1 - 0.049 14.6 11.2 0.064 14.2 11.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LptF_LptG PF03739.14 XP_667948.1 - 0.083 11.7 2.8 0.088 11.6 2.8 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Nairovirus_M PF07948.11 XP_667948.1 - 0.2 9.8 2.6 0.16 10.2 2.6 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Oxidored_q3 PF00499.20 XP_667948.1 - 0.22 11.2 4.2 5.5 6.7 1.5 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2101 PF09874.9 XP_667948.1 - 0.29 10.8 5.5 0.32 10.7 5.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) TctB PF07331.11 XP_667948.1 - 0.29 11.4 4.2 0.35 11.1 4.2 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.9 XP_667948.1 - 0.42 9.3 3.2 0.46 9.2 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2681 PF10883.8 XP_667948.1 - 3.4 8.1 6.2 2.1 8.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) zf-RING_2 PF13639.6 XP_667949.1 - 1.2e-09 38.4 6.4 2.1e-09 37.6 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 XP_667949.1 - 1.3e-08 34.5 6.6 2.4e-08 33.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 XP_667949.1 - 2.3e-07 31.0 8.5 1e-06 28.9 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 XP_667949.1 - 8.3e-07 28.8 5.7 1.6e-06 27.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_667949.1 - 1.7e-06 27.7 4.0 3.4e-06 26.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_667949.1 - 1.8e-05 24.6 2.0 1.8e-05 24.6 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 XP_667949.1 - 3.5e-05 23.6 4.6 6.9e-05 22.6 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 XP_667949.1 - 0.00055 19.9 5.5 0.0019 18.1 5.7 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 XP_667949.1 - 0.00062 19.3 3.2 0.0013 18.3 3.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 XP_667949.1 - 0.0017 18.4 1.3 0.0038 17.3 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1201 PF06716.11 XP_667949.1 - 0.0031 17.5 1.9 0.0031 17.5 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1201) zf-RING_11 PF17123.5 XP_667949.1 - 0.0048 16.6 2.4 0.0048 16.6 2.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_6 PF14835.6 XP_667949.1 - 0.058 13.3 1.7 0.11 12.4 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 XP_667949.1 - 0.069 13.3 3.3 0.85 9.8 3.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Tugs PF17840.1 XP_667949.1 - 0.13 12.5 0.4 0.29 11.3 0.4 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain zf-RING-like PF08746.11 XP_667949.1 - 0.17 12.2 5.3 0.31 11.4 5.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 XP_667949.1 - 0.27 11.4 5.6 0.64 10.2 5.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 XP_667949.1 - 0.54 10.4 4.7 1.5 9.0 4.7 1.8 1 0 0 1 1 1 0 RING-variant domain CTU2 PF10288.9 XP_667949.1 - 0.68 10.2 5.2 2.7 8.3 4.6 2.3 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 SHMT PF00464.19 XP_667951.1 - 1.9e-74 250.7 0.0 1.1e-73 248.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Sec20 PF03908.13 XP_667952.1 - 0.027 14.4 2.0 0.098 12.6 2.0 2.0 1 0 0 1 1 1 0 Sec20 SHMT PF00464.19 XP_667954.1 - 6.7e-122 406.9 0.0 1.1e-121 406.3 0.0 1.3 1 1 0 1 1 1 1 Serine hydroxymethyltransferase PTP_tm PF18861.1 XP_667956.1 - 0.14 12.1 3.0 0.25 11.3 3.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Methyltr_RsmF_N PF17125.5 XP_667958.1 - 0.078 13.5 0.1 0.082 13.4 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Glycos_transf_2 PF00535.26 XP_667959.1 - 2.3e-18 66.6 0.2 3.3e-18 66.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 XP_667959.1 - 0.011 15.3 0.3 0.025 14.0 0.2 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 XP_667959.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Peptidase_M17 PF00883.21 XP_667960.1 - 3.5e-99 332.0 0.1 4.3e-99 331.7 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain His_Phos_1 PF00300.22 XP_667961.1 - 3.7e-30 105.1 0.1 8.9e-30 103.8 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PUF PF00806.19 XP_667962.1 - 0.0011 18.6 0.2 0.016 14.9 0.0 3.2 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat SWIB PF02201.18 XP_667962.1 - 0.0034 17.2 3.1 1.6 8.7 0.1 3.4 3 0 0 3 3 3 2 SWIB/MDM2 domain zf-RanBP PF00641.18 XP_667964.1 - 0.02 14.2 9.3 0.078 12.3 9.3 2.1 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Peptidase_M16_C PF05193.21 XP_667965.1 - 4.5e-06 26.8 0.1 0.00021 21.4 0.2 2.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain ADH_N PF08240.12 XP_667966.1 - 7.4e-28 96.6 6.1 1.4e-27 95.7 6.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 XP_667966.1 - 3.6e-19 69.0 0.2 7.5e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 XP_667966.1 - 2e-06 28.9 0.0 3.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 XP_667966.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 XP_667966.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 XP_667966.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 XP_667966.1 - 0.057 12.7 0.2 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CagY_I PF14585.6 XP_667967.1 - 0.16 12.1 7.6 0.18 11.9 2.6 2.9 2 1 0 2 2 2 0 CagY type 1 repeat WxL PF13731.6 XP_667968.1 - 0.013 15.5 2.6 0.061 13.3 0.1 2.3 2 0 0 2 2 2 0 WxL domain surface cell wall-binding Ank_2 PF12796.7 XP_667973.1 - 0.00056 20.5 0.2 0.00097 19.7 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_667973.1 - 0.0016 18.9 0.1 0.0026 18.3 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 XP_667973.1 - 0.014 15.9 0.1 7.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 XP_667975.1 - 8.8e-67 225.2 0.3 1.3e-43 149.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_667975.1 - 1.9e-34 119.1 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 XP_667975.1 - 5.4e-14 52.4 0.2 1e-07 32.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 XP_667975.1 - 4e-09 35.4 0.7 0.018 14.6 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 XP_667975.1 - 5.5e-08 32.1 0.6 0.013 15.4 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 XP_667975.1 - 2.1e-07 30.7 0.9 0.0081 16.0 0.0 3.7 1 1 2 3 3 3 2 EF-hand domain pair Kdo PF06293.14 XP_667975.1 - 2.4e-06 27.1 0.2 7.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 XP_667975.1 - 7.1e-05 21.7 0.0 0.00019 20.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_5 PF13202.6 XP_667975.1 - 0.00065 19.1 2.1 0.73 9.4 0.1 2.7 2 0 0 2 2 2 2 EF hand Kinase-like PF14531.6 XP_667975.1 - 0.0037 16.6 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 XP_667975.1 - 0.0042 16.7 0.2 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 XP_667975.1 - 0.0053 16.7 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 XP_667975.1 - 0.18 11.4 1.5 0.56 9.7 0.1 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF4131 PF13567.6 XP_667976.1 - 0.088 12.5 0.8 0.13 11.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OAD_gamma PF04277.13 XP_667976.1 - 3 8.5 5.4 6.1 7.5 5.4 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Hat1_N PF10394.9 XP_667977.1 - 3.8e-19 69.5 1.2 2.4e-18 66.9 0.6 2.4 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 XP_667977.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 MOZ/SAS family DUF148 PF02520.17 XP_667977.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF148 Acetyltransf_10 PF13673.7 XP_667977.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C3HC4_3 PF13920.6 XP_667978.1 - 4.3e-06 26.5 9.4 4.3e-06 26.5 9.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ADD_DNMT3 PF17980.1 XP_667978.1 - 0.063 13.3 9.9 0.3 11.1 7.2 2.4 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 ATP_bind_1 PF03029.17 XP_667979.1 - 3.4e-71 239.9 0.0 3.8e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 XP_667979.1 - 0.0005 20.2 0.0 0.00062 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 XP_667979.1 - 0.0061 16.0 1.0 2.2 7.7 0.0 3.0 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 XP_667979.1 - 0.008 16.1 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 NTPase cobW PF02492.19 XP_667979.1 - 0.011 15.4 0.0 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 XP_667979.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 XP_667979.1 - 0.018 15.5 0.1 0.034 14.6 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 XP_667979.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 XP_667979.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 XP_667979.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 XP_667979.1 - 0.044 13.9 0.1 0.79 9.8 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 XP_667979.1 - 0.047 14.2 0.0 0.094 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 XP_667979.1 - 0.067 13.5 0.0 0.71 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 XP_667979.1 - 0.068 13.0 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 XP_667979.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 XP_667979.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 XP_667979.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 XP_667979.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.10 XP_667979.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 XP_667979.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 XP_667979.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sulfate_transp PF00916.20 XP_667980.1 - 7.6e-54 182.9 20.2 3.3e-35 121.5 7.7 2.2 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 XP_667980.1 - 2.8e-10 39.9 0.2 8.3e-10 38.3 0.2 1.9 1 1 0 1 1 1 1 STAS domain zf-C3HC4 PF00097.25 XP_667981.1 - 7.1e-06 25.8 9.6 7.1e-06 25.8 9.6 4.8 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 XP_667981.1 - 1e-05 25.6 8.3 1e-05 25.6 8.3 4.8 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 XP_667981.1 - 2.9e-05 23.9 10.8 2.9e-05 23.9 10.8 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_667981.1 - 6.9e-05 22.6 14.3 6.9e-05 22.6 14.3 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_667981.1 - 0.00019 21.4 9.3 0.00019 21.4 9.3 4.4 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 XP_667981.1 - 0.00024 21.4 15.0 0.00024 21.4 15.0 4.0 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 XP_667981.1 - 0.00032 20.6 14.3 0.00032 20.6 14.3 4.2 4 1 1 5 5 5 1 zinc-RING finger domain U-box PF04564.15 XP_667981.1 - 0.0034 17.5 1.1 0.52 10.5 0.3 2.6 2 0 0 2 2 2 1 U-box domain Rubredoxin PF00301.20 XP_667981.1 - 0.0084 16.1 5.4 0.28 11.2 0.1 4.2 4 0 0 4 4 4 1 Rubredoxin NDUFB10 PF10249.9 XP_667981.1 - 6.2 7.4 8.1 0.53 10.8 0.5 2.7 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase subunit 10 Sortilin-Vps10 PF15902.5 XP_667982.1 - 1.6e-95 320.5 15.0 7.4e-95 318.3 15.0 1.9 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 XP_667982.1 - 4.6e-37 128.0 0.7 8.6e-37 127.1 0.7 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 XP_667982.1 - 0.0063 16.3 17.5 0.72 10.1 0.1 6.9 7 0 0 7 7 7 2 BNR/Asp-box repeat BNR_6 PF15899.5 XP_667982.1 - 0.019 15.0 0.0 0.19 11.8 0.1 2.8 2 0 0 2 2 2 0 BNR-Asp box repeat UCR_UQCRX_QCR9 PF05365.12 XP_667982.1 - 0.24 11.4 2.1 0.88 9.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like cNMP_binding PF00027.29 XP_667983.1 - 2.3e-42 143.0 0.0 7.2e-22 77.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ribosomal_S11 PF00411.19 XP_667984.1 - 3.3e-30 104.7 1.2 3.9e-30 104.5 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 SprT-like PF10263.9 XP_667986.1 - 1.1e-18 67.2 0.1 2.7e-18 65.9 0.1 1.7 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 XP_667986.1 - 0.0092 15.9 1.8 0.0092 15.9 1.8 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 XP_667986.1 - 0.011 15.8 0.5 0.027 14.6 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Chordopox_G3 PF06129.12 XP_667986.1 - 0.1 13.3 0.7 1 10.1 0.4 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Notch PF00066.17 XP_667989.1 - 8e-37 125.4 118.7 1.1e-07 32.2 14.5 6.3 4 1 2 6 6 6 6 LNR domain UPRTase PF14681.6 XP_667990.1 - 3.6e-62 209.5 0.0 5.2e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 XP_667990.1 - 2.1e-47 161.4 0.1 3e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 XP_667990.1 - 0.00011 21.9 0.1 0.61 9.7 0.0 2.4 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 XP_667990.1 - 0.0065 17.0 0.1 0.019 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 XP_667990.1 - 0.021 14.6 0.1 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 XP_667990.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 XP_667990.1 - 0.042 13.1 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 XP_667990.1 - 0.094 13.1 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 XP_667990.1 - 0.38 11.2 2.5 8 6.9 2.5 2.3 1 1 0 1 1 1 0 AAA domain DnaJ PF00226.31 XP_667991.1 - 1.5e-19 69.9 0.3 2.1e-19 69.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Tmpp129 PF10272.9 XP_667991.1 - 0.021 14.1 0.2 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative transmembrane protein precursor DUF2269 PF10027.9 XP_667991.1 - 0.024 14.7 0.2 0.038 14.0 0.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) 7TMR-DISM_7TM PF07695.11 XP_667991.1 - 0.026 14.4 0.2 6.3 6.6 0.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2298 PF10060.9 XP_667991.1 - 0.084 11.6 0.0 6.9 5.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) DUF2299 PF10061.9 XP_667991.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) LRR_4 PF12799.7 XP_667992.1 - 0.00016 22.0 61.5 0.0079 16.6 0.5 8.6 5 2 3 9 9 9 7 Leucine Rich repeats (2 copies) DnaJ PF00226.31 XP_667995.1 - 1.4e-06 28.4 0.3 3.9e-06 26.9 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L1 PF00687.21 XP_667996.1 - 2.5e-42 144.9 1.6 3e-42 144.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 XP_667996.1 - 0.048 13.7 4.9 0.069 13.2 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function MetOD2 PF18548.1 XP_667996.1 - 0.087 12.9 2.9 0.35 11.0 0.1 2.5 3 0 0 3 3 3 0 Metanogen output domain 2 SNRNP27 PF08648.12 XP_667997.1 - 1.3e-22 79.6 0.2 1.3e-22 79.6 0.2 1.9 2 1 1 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 XP_667998.1 - 1.7e-21 76.5 1.3 2.5e-21 76.0 0.2 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 TraI_2_C PF07515.11 XP_667998.1 - 0.052 13.5 0.6 0.071 13.1 0.6 1.3 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term FTO_NTD PF12933.7 XP_667998.1 - 0.22 10.8 2.1 0.27 10.5 2.1 1.1 1 0 0 1 1 1 0 FTO catalytic domain COPIIcoated_ERV PF07970.12 XP_667999.1 - 1.9e-45 155.5 2.3 2.7e-45 154.9 2.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 XP_667999.1 - 1.6e-20 73.2 1.1 3.2e-20 72.2 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) C2 PF00168.30 XP_668000.1 - 7e-32 109.8 0.0 2.6e-07 30.9 0.0 5.7 5 0 0 5 5 5 5 C2 domain Ferlin_C PF16165.5 XP_668000.1 - 4.5e-07 29.9 0.0 1.6e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Ferlin C-terminus FerI PF08151.12 XP_668000.1 - 0.0099 15.9 0.2 0.7 10.0 0.0 2.9 2 0 0 2 2 2 1 FerI (NUC094) domain PTEN_C2 PF10409.9 XP_668000.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Snf7 PF03357.21 XP_668001.1 - 4.7e-10 39.3 11.8 8.2e-10 38.6 11.8 1.3 1 0 0 1 1 1 1 Snf7 GTP_EFTU PF00009.27 XP_668002.1 - 6.7e-67 224.8 0.1 9.9e-67 224.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 XP_668002.1 - 3.3e-33 114.0 0.0 9.5e-33 112.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 XP_668002.1 - 9.9e-22 76.8 0.0 2.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 XP_668002.1 - 1.1e-14 54.2 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 XP_668002.1 - 5.5e-12 45.9 0.1 1.2e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 XP_668002.1 - 0.00038 20.5 0.0 0.00099 19.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 XP_668002.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Rep_fac_C PF08542.11 XP_668003.1 - 3.9e-12 46.4 0.1 8.6e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 XP_668003.1 - 9.6e-12 45.0 0.6 1.6e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 XP_668003.1 - 0.0001 22.5 0.0 0.0003 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 XP_668003.1 - 0.0022 18.4 0.1 0.0043 17.5 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 XP_668003.1 - 0.0041 16.9 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Ig_Tie2_1 PF10430.9 XP_668003.1 - 0.0048 17.3 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 AAA_30 PF13604.6 XP_668003.1 - 0.15 11.8 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 XP_668005.1 - 0.024 13.2 3.4 0.018 13.6 3.4 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 XP_668005.1 - 0.2 10.5 7.6 0.18 10.6 6.7 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 XP_668005.1 - 0.66 10.6 20.1 0.96 10.0 20.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4614 PF15391.6 XP_668005.1 - 0.86 9.6 14.8 1.2 9.1 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Cation_efflux PF01545.21 XP_668006.1 - 2e-44 151.7 17.3 3.4e-44 151.0 17.3 1.4 1 1 0 1 1 1 1 Cation efflux family TIM PF00121.18 XP_668007.1 - 3.2e-89 298.5 0.1 3.6e-89 298.3 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EF-hand_8 PF13833.6 XP_668007.1 - 0.052 13.4 0.2 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair Zn_ribbon_17 PF17120.5 XP_668008.1 - 2.7e-06 26.9 11.7 9.8e-06 25.1 11.7 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Glycolytic PF00274.19 XP_668009.1 - 2.9e-162 539.3 0.0 3.3e-162 539.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Peptidase_M61 PF05299.12 XP_668009.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 M61 glycyl aminopeptidase ER_lumen_recept PF00810.18 XP_668010.1 - 6.6e-37 127.6 5.5 6.6e-37 127.6 5.5 2.1 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 XP_668010.1 - 0.12 12.2 0.1 0.12 12.2 0.1 3.8 3 1 0 3 3 3 0 PQ loop repeat Ribosomal_L27e PF01777.18 XP_668011.1 - 1.9e-20 73.0 0.8 2.6e-20 72.5 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 XP_668011.1 - 0.0017 18.2 0.2 0.0029 17.5 0.2 1.4 1 0 0 1 1 1 1 KOW motif ATHILA PF03078.15 XP_668011.1 - 0.032 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family CGI-121 PF08617.10 XP_668012.1 - 4.7e-06 26.8 0.6 7.2e-06 26.2 0.5 1.4 1 1 0 1 1 1 1 Kinase binding protein CGI-121 RabGAP-TBC PF00566.18 XP_668012.1 - 0.044 13.4 3.3 0.053 13.2 3.3 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain 14-3-3 PF00244.20 XP_668013.1 - 5.2e-40 137.3 5.7 6.5e-40 137.0 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein CNOT1_TTP_bind PF16417.5 XP_668013.1 - 0.0087 15.3 0.6 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF2225 PF09986.9 XP_668013.1 - 0.0096 15.7 2.4 0.07 12.8 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_12 PF13424.6 XP_668013.1 - 0.016 15.5 0.1 0.078 13.3 0.2 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 XP_668013.1 - 0.016 16.0 0.1 4.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668013.1 - 0.019 14.8 2.5 3.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668013.1 - 0.047 13.9 0.3 8 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668013.1 - 0.047 13.8 2.5 4.4 7.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 XP_668014.1 - 8.4e-10 38.6 2.4 1.5e-09 37.8 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 XP_668015.1 - 2.3e-33 115.7 0.0 9.1e-19 67.8 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668015.1 - 1.8e-07 30.7 0.0 0.021 14.1 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase XAP5 PF04921.14 XP_668016.1 - 2.9e-24 86.3 7.1 3.8e-24 85.9 7.1 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4207 PF13904.6 XP_668016.1 - 0.074 12.7 6.0 0.16 11.6 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) ALS2CR11 PF15729.5 XP_668016.1 - 0.23 10.6 7.9 0.29 10.2 7.9 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 V-SNARE_C PF12352.8 XP_668019.1 - 8.4e-11 42.0 2.9 8.4e-11 42.0 2.9 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 XP_668019.1 - 0.00068 19.5 0.3 0.00068 19.5 0.3 2.6 2 1 0 2 2 2 1 Sec20 BRE1 PF08647.11 XP_668019.1 - 0.0022 18.0 10.9 0.0043 17.1 3.9 2.4 1 1 1 2 2 2 1 BRE1 E3 ubiquitin ligase ASD1 PF08688.10 XP_668019.1 - 0.0074 16.7 0.5 0.015 15.7 0.3 1.7 1 1 1 2 2 2 1 Apx/Shroom domain ASD1 Allexi_40kDa PF05549.11 XP_668019.1 - 0.017 14.7 1.1 0.024 14.2 1.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein HTH_19 PF12844.7 XP_668019.1 - 0.043 13.9 0.2 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain SCP-1 PF05483.12 XP_668019.1 - 0.11 10.5 8.5 0.074 11.1 6.0 1.6 1 1 1 2 2 2 0 Synaptonemal complex protein 1 (SCP-1) Syntaxin-18_N PF10496.9 XP_668019.1 - 0.38 11.0 4.7 1 9.6 2.1 2.6 1 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus KxDL PF10241.9 XP_668019.1 - 0.45 10.8 6.7 12 6.3 2.1 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein MSC PF09402.10 XP_668019.1 - 1.1 8.7 6.2 1.8 8.0 6.1 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain V-SNARE PF05008.15 XP_668019.1 - 2 8.9 10.1 2.3 8.6 0.9 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Fzo_mitofusin PF04799.13 XP_668019.1 - 3 7.4 6.5 6.8 6.2 2.0 2.4 2 0 0 2 2 2 0 fzo-like conserved region LSM PF01423.22 XP_668020.1 - 9.3e-22 76.5 0.5 1.2e-21 76.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain Utp21 PF04192.12 XP_668022.1 - 3.7e-42 144.4 6.3 6.6e-42 143.6 6.3 1.5 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 XP_668022.1 - 8.6e-11 42.0 1.1 0.00095 19.4 0.0 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 XP_668022.1 - 6e-08 33.2 6.1 0.055 14.4 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Hira PF07569.11 XP_668022.1 - 0.00028 20.7 0.3 0.00028 20.7 0.3 3.0 5 0 0 5 5 5 1 TUP1-like enhancer of split YccV-like PF08755.11 XP_668023.1 - 2.3e-18 66.5 0.1 6.9e-18 65.0 0.1 1.9 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.13 XP_668023.1 - 2.8e-07 31.4 4.6 3e-07 31.3 0.0 3.4 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 XP_668023.1 - 0.00093 18.9 0.0 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF5503 PF17607.2 XP_668026.1 - 0.19 12.1 3.0 0.63 10.4 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5503) Pallilysin PF18663.1 XP_668028.1 - 0.014 15.3 0.0 0.071 13.1 0.0 2.2 1 0 0 1 1 1 0 Pallilysin beta barrel domain TetR_C_27 PF17935.1 XP_668028.1 - 0.072 13.2 0.0 5.1 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HsbA PF12296.8 XP_668029.1 - 0.0062 17.0 0.7 0.54 10.7 0.0 4.0 5 0 0 5 5 5 1 Hydrophobic surface binding protein A DUF2873 PF11395.8 XP_668029.1 - 0.24 11.3 0.8 0.57 10.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) CHD5 PF04420.14 XP_668029.1 - 0.94 9.3 6.9 0.12 12.2 1.3 2.5 2 0 0 2 2 2 0 CHD5-like protein DnaJ PF00226.31 XP_668030.1 - 1.8e-21 76.0 0.4 4.4e-21 74.8 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 XP_668030.1 - 1.5e-14 53.8 0.1 2.3e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain CrgA PF06781.12 XP_668030.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Cell division protein CrgA TraL PF07178.11 XP_668030.1 - 0.093 13.2 0.4 0.093 13.2 0.4 2.2 3 0 0 3 3 3 0 TraL protein PspB PF06667.12 XP_668030.1 - 0.39 10.8 3.5 1 9.5 0.8 2.7 2 0 0 2 2 2 0 Phage shock protein B Pkinase PF00069.25 XP_668032.1 - 5.2e-71 239.1 0.1 6.7e-71 238.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668032.1 - 4.5e-38 131.0 0.0 5.8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 XP_668032.1 - 2.4e-07 30.1 3.3 4.5e-07 29.1 3.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 XP_668032.1 - 1.9e-06 27.5 0.0 0.00013 21.3 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 XP_668032.1 - 0.0052 16.2 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 XP_668032.1 - 0.014 14.2 0.1 0.031 13.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 XP_668032.1 - 0.029 14.3 0.0 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 XP_668032.1 - 0.053 13.1 0.2 0.12 12.0 0.1 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4075 PF13294.6 XP_668033.1 - 0.0015 18.7 1.8 0.69 10.1 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4075) Tox-REase-7 PF15649.6 XP_668033.1 - 0.031 14.6 0.6 0.085 13.2 0.6 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 ApoC-I PF04691.12 XP_668033.1 - 0.21 11.5 2.5 9.8 6.2 0.1 3.2 2 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) MSC PF09402.10 XP_668034.1 - 7.2e-15 55.3 0.7 4.6e-14 52.6 0.2 2.0 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain MMtag PF10159.9 XP_668035.1 - 6e-17 61.7 1.4 6e-17 61.7 1.4 2.1 3 0 0 3 3 3 1 Multiple myeloma tumor-associated DUF1235 PF06822.12 XP_668035.1 - 0.062 12.6 0.3 0.074 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Zn_ribbon_2 PF12674.7 XP_668036.1 - 0.094 13.4 0.7 1 10.1 0.1 2.5 2 1 0 2 2 2 0 Putative zinc ribbon domain DEAD PF00270.29 XP_668037.1 - 1e-41 142.6 0.0 1.9e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668037.1 - 1.2e-30 106.1 0.0 6.8e-30 103.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668037.1 - 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 XP_668037.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 XP_668037.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 XP_668037.1 - 0.0034 17.7 0.0 0.0066 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 XP_668037.1 - 0.0078 16.5 0.1 0.032 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 XP_668037.1 - 0.066 12.9 0.0 0.089 12.4 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Helicase_RecD PF05127.14 XP_668037.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Helicase FF PF01846.19 XP_668038.1 - 0.0017 18.5 5.0 0.1 12.8 0.0 4.1 3 1 0 3 3 3 2 FF domain WD40 PF00400.32 XP_668039.1 - 3.4e-35 119.4 13.5 2.4e-07 31.3 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_668039.1 - 2.1e-08 34.3 1.9 0.23 11.8 0.1 5.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 XP_668039.1 - 9e-05 21.3 2.0 0.14 10.7 0.1 3.7 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 XP_668039.1 - 0.00047 19.0 3.5 1 8.0 1.0 3.9 1 1 3 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 XP_668039.1 - 0.008 15.5 0.1 1.1 8.5 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Ricin_B_lectin PF00652.22 XP_668039.1 - 0.024 14.9 0.1 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain SBBP PF06739.11 XP_668039.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Beta-propeller repeat PX PF00787.24 XP_668040.1 - 5.6e-14 52.1 0.3 1.3e-13 51.0 0.3 1.6 1 0 0 1 1 1 1 PX domain Atg8 PF02991.16 XP_668041.1 - 3.5e-14 52.8 0.3 8.7e-14 51.6 0.3 1.6 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 XP_668041.1 - 0.00036 20.9 0.3 0.00058 20.2 0.2 1.3 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Seryl_tRNA_N PF02403.22 XP_668043.1 - 0.0026 18.0 2.3 0.0038 17.4 2.3 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SelP_N PF04592.14 XP_668043.1 - 5.7 6.3 26.0 9 5.6 26.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_BLRF2 PF05812.12 XP_668044.1 - 0.013 15.6 1.7 1.7 8.8 0.3 2.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF1640 PF07798.11 XP_668044.1 - 0.028 14.5 3.2 0.054 13.6 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 XP_668044.1 - 0.16 12.2 7.0 2.4 8.4 0.9 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Fungal_TACC PF12709.7 XP_668044.1 - 0.25 11.8 4.4 13 6.4 0.2 3.3 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 XP_668044.1 - 0.26 11.6 2.0 2.9 8.3 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 XP_668044.1 - 0.33 11.1 6.2 4.1 7.6 0.2 3.4 3 0 0 3 3 3 0 bZIP transcription factor YabA PF06156.13 XP_668044.1 - 0.51 11.0 10.6 2.6 8.7 0.3 3.3 1 1 2 3 3 3 0 Initiation control protein YabA NRBF2 PF08961.10 XP_668044.1 - 0.57 9.8 7.2 1.5 8.4 2.2 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 XP_668044.1 - 0.6 10.6 12.9 0.54 10.7 4.0 3.5 1 1 2 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 XP_668044.1 - 0.73 10.1 4.6 20 5.5 0.2 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 XP_668044.1 - 1 9.5 8.1 6.9 6.8 1.0 3.4 3 0 0 3 3 3 0 Basic region leucine zipper APG6_N PF17675.1 XP_668044.1 - 1 9.9 7.6 0.47 11.0 3.8 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 XP_668044.1 - 1.1 9.1 6.4 9.1 6.1 0.4 2.9 3 0 0 3 3 3 0 Septum formation initiator Rootletin PF15035.6 XP_668044.1 - 1.2 9.1 11.5 0.72 9.9 0.5 2.8 2 2 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 XP_668044.1 - 2.1 9.0 5.0 0.98 10.1 0.3 2.8 4 0 0 4 4 4 0 SlyX Cep57_CLD_2 PF14197.6 XP_668044.1 - 2.6 8.2 11.5 7.5 6.7 0.3 4.0 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 LMBR1 PF04791.16 XP_668044.1 - 5 5.9 6.6 4.2 6.2 5.3 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein PRKG1_interact PF15898.5 XP_668044.1 - 6.4 7.7 13.1 7.4 7.5 0.3 3.2 2 1 2 4 4 3 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 XP_668044.1 - 7.5 7.0 9.0 4.8 7.6 2.2 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) NAP PF00956.18 XP_668045.1 - 9.3e-16 57.8 17.0 1.2e-13 50.8 11.4 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF3836 PF12930.7 XP_668045.1 - 0.044 13.5 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) WD40 PF00400.32 XP_668046.1 - 0.0045 17.8 0.6 1.4 9.9 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.11 XP_668046.1 - 0.0078 16.1 0.0 0.0096 15.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 XP_668046.1 - 0.025 14.9 0.0 0.33 11.3 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_668046.1 - 0.06 12.7 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 XP_668047.1 - 0.0081 16.4 0.0 0.0087 16.3 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 XP_668047.1 - 0.0088 16.0 0.2 0.35 10.9 0.0 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 XP_668047.1 - 0.024 14.3 0.0 0.024 14.3 0.0 2.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 XP_668047.1 - 0.099 11.3 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) MutS_V PF00488.21 XP_668048.1 - 7.9e-75 251.0 0.1 1.3e-74 250.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 XP_668048.1 - 1.9e-23 83.7 0.7 1.9e-23 83.7 0.7 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 XP_668048.1 - 4.2e-05 23.8 1.9 0.00011 22.5 0.2 2.6 2 0 0 2 2 2 1 MutS domain II DUF2884 PF11101.8 XP_668048.1 - 0.0071 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) AAA_27 PF13514.6 XP_668048.1 - 0.011 15.4 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTP_transferase PF00483.23 XP_668049.1 - 1.3e-13 51.1 0.0 5.5e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 XP_668049.1 - 1.5e-10 40.3 11.0 2.4e-05 23.9 4.4 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 XP_668049.1 - 3.4e-06 27.5 0.0 7e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 XP_668049.1 - 0.00061 18.0 1.8 0.0011 17.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 XP_668049.1 - 0.0074 15.3 5.2 0.032 13.2 5.5 1.7 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 XP_668049.1 - 0.024 14.4 12.9 0.66 9.8 10.2 3.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase MMR_HSR1 PF01926.23 XP_668050.1 - 1.7e-10 41.0 0.0 1.1e-09 38.4 0.0 2.4 2 2 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 XP_668050.1 - 2.5e-08 34.1 1.2 2e-06 27.9 0.1 2.9 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 XP_668050.1 - 3.4e-07 30.0 0.0 1.2e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 XP_668050.1 - 0.00011 22.1 1.1 0.0029 17.5 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase SRPRB PF09439.10 XP_668050.1 - 0.0032 16.9 0.3 0.0096 15.4 0.1 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 XP_668050.1 - 0.0033 17.9 1.9 0.012 16.2 1.9 2.2 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 XP_668050.1 - 0.0034 16.7 0.1 0.0034 16.7 0.1 2.1 2 1 0 2 2 2 1 Septin Roc PF08477.13 XP_668050.1 - 0.004 17.4 0.1 0.013 15.8 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 XP_668050.1 - 0.026 14.3 3.7 1.1 9.0 0.1 3.0 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 XP_668050.1 - 0.034 13.7 0.5 0.85 9.1 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AIG1 PF04548.16 XP_668050.1 - 0.05 12.9 4.9 0.54 9.6 0.0 2.9 3 0 0 3 3 3 0 AIG1 family AAA_29 PF13555.6 XP_668050.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 XP_668050.1 - 0.3 10.7 2.9 3.5 7.2 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 XP_668052.1 - 5.9e-45 153.7 27.5 2.4e-43 148.4 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 XP_668053.1 - 5.3e-36 124.0 0.1 1.1e-35 123.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668053.1 - 1.1e-27 96.6 1.9 2.6e-27 95.4 0.3 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668053.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 XP_668053.1 - 0.0048 16.3 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 XP_668053.1 - 0.076 12.3 0.0 1.9 7.7 0.0 2.2 1 1 0 2 2 2 0 tRNA synthetases class I (W and Y) ChaC PF04752.12 XP_668053.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 ChaC-like protein Aa_trans PF01490.18 XP_668054.1 - 5.6e-10 38.5 46.2 1e-05 24.4 30.2 2.3 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Patatin PF01734.22 XP_668055.1 - 1e-07 32.3 0.1 3.1e-06 27.5 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 XP_668056.1 - 1.1e-22 81.2 0.8 7.7e-22 78.5 0.8 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase YbaB_DNA_bd PF02575.16 XP_668057.1 - 0.017 15.3 0.3 0.084 13.1 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Fe_hyd_SSU PF02256.17 XP_668057.1 - 0.098 12.7 0.5 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit UPF0449 PF15136.6 XP_668057.1 - 0.14 12.6 0.7 4.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 UQ_con PF00179.26 XP_668058.1 - 4.2e-15 55.6 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tsc35 PF15079.6 XP_668059.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 ING PF12998.7 XP_668059.1 - 0.27 11.8 4.4 0.31 11.6 2.2 2.2 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Dcc1 PF09724.9 XP_668061.1 - 9.1e-32 110.7 0.6 2.1e-30 106.2 0.6 2.3 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 AATF-Che1 PF13339.6 XP_668062.1 - 4e-14 53.5 3.3 8.3e-14 52.4 3.3 1.5 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 XP_668063.1 - 3e-18 66.1 0.0 3.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal EII-GUT PF03608.13 XP_668063.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor DEAD PF00270.29 XP_668065.1 - 7.9e-44 149.5 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668065.1 - 2e-28 98.9 0.8 1.6e-27 96.0 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668065.1 - 0.0003 20.8 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SURF6 PF04935.12 XP_668066.1 - 1.3e-12 47.9 41.5 1.4e-12 47.8 40.4 1.6 1 1 1 2 2 2 1 Surfeit locus protein 6 DUF3972 PF13118.6 XP_668067.1 - 0.037 14.5 1.3 0.037 14.5 1.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3972) Histone_HNS PF00816.21 XP_668067.1 - 0.35 11.7 8.3 1.7 9.5 0.5 2.5 2 0 0 2 2 2 0 H-NS histone family Prominin PF05478.11 XP_668067.1 - 1.7 6.5 11.2 1.6 6.6 10.0 1.4 1 1 0 1 1 1 0 Prominin Fez1 PF06818.15 XP_668067.1 - 3.4 8.1 22.2 1 9.8 18.9 1.7 2 0 0 2 2 2 0 Fez1 APG6_N PF17675.1 XP_668067.1 - 5.5 7.5 15.4 0.53 10.8 6.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region SAM_Exu PF18609.1 XP_668067.1 - 6.6 6.9 7.4 1.5 9.0 1.9 2.5 2 0 0 2 2 2 0 Exuperantia SAM-like domain DUF778 PF05608.12 XP_668068.1 - 4.7 7.5 10.4 1.2e+02 3.0 10.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) ubiquitin PF00240.23 XP_668071.1 - 7.8e-12 44.8 0.0 0.22 11.3 0.0 8.9 9 1 0 9 9 9 3 Ubiquitin family Rad60-SLD PF11976.8 XP_668071.1 - 4.6e-10 39.2 1.5 0.36 10.7 0.0 7.4 8 1 0 8 8 8 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 XP_668071.1 - 9.7e-06 26.0 0.0 0.03 14.8 0.0 4.5 4 0 0 4 4 4 1 Ubiquitin-like domain DUF2713 PF10897.8 XP_668073.1 - 0.089 12.4 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) ThiF PF00899.21 XP_668074.1 - 3.3e-44 151.1 0.0 4.3e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 XP_668074.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 XP_668075.1 - 1.8e-111 372.5 0.0 2.5e-111 372.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 XP_668075.1 - 2.9e-18 65.6 0.1 6.6e-17 61.2 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 XP_668075.1 - 3.5e-17 62.9 0.7 1.3e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 XP_668076.1 - 3.5e-59 200.5 0.0 2.3e-58 197.8 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 XP_668076.1 - 2.9e-08 33.8 2.2 0.0001 22.1 0.0 2.5 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase PFK PF00365.20 XP_668076.1 - 0.032 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase Mg-por_mtran_C PF07109.11 XP_668076.1 - 0.095 13.1 0.0 8.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus YbfN PF13982.6 XP_668077.1 - 0.0045 17.2 0.2 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 YbfN-like lipoprotein Laminin_I PF06008.14 XP_668077.1 - 0.0059 16.3 5.9 0.0069 16.1 5.9 1.0 1 0 0 1 1 1 1 Laminin Domain I Spc7 PF08317.11 XP_668077.1 - 0.015 14.2 9.2 0.016 14.1 9.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein RmuC PF02646.16 XP_668077.1 - 0.044 12.9 4.5 2.3 7.3 3.2 2.0 1 1 0 2 2 2 0 RmuC family GAS PF13851.6 XP_668077.1 - 0.046 13.1 11.9 0.14 11.5 11.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 XP_668077.1 - 0.049 14.2 7.0 0.062 13.9 6.0 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MSC PF09402.10 XP_668077.1 - 0.057 12.9 2.2 0.057 12.9 2.2 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain CENP-K PF11802.8 XP_668077.1 - 0.076 12.6 8.2 0.09 12.3 8.2 1.0 1 0 0 1 1 1 0 Centromere-associated protein K TMPIT PF07851.13 XP_668077.1 - 0.11 11.8 5.2 0.12 11.6 5.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 XP_668077.1 - 0.12 12.1 6.2 0.15 11.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3782 PF12644.7 XP_668077.1 - 0.13 12.5 4.0 0.21 11.8 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF1664 PF07889.12 XP_668077.1 - 0.22 11.6 4.3 0.39 10.7 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CorA PF01544.18 XP_668077.1 - 0.28 10.4 4.2 0.34 10.2 4.2 1.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PI3K_P85_iSH2 PF16454.5 XP_668077.1 - 0.33 10.5 10.5 0.27 10.8 4.3 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Arc_PepC_II PF06847.11 XP_668077.1 - 0.39 11.3 1.7 2 9.0 1.7 2.0 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II APG6_N PF17675.1 XP_668077.1 - 0.41 11.2 11.4 0.64 10.5 11.4 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Rho_Binding PF08912.11 XP_668077.1 - 0.54 11.1 10.3 0.64 10.9 2.9 2.2 1 1 1 2 2 2 0 Rho Binding FapA PF03961.13 XP_668077.1 - 0.72 8.4 7.1 0.81 8.2 7.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A KxDL PF10241.9 XP_668077.1 - 1 9.7 6.5 0.8 10.0 4.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein CCDC-167 PF15188.6 XP_668077.1 - 3.5 8.0 10.9 1.8 8.9 8.0 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 MRPL52 PF18699.1 XP_668077.1 - 5.2 7.3 8.7 1.2 9.4 4.4 1.9 1 1 1 2 2 2 0 Mitoribosomal protein mL52 Pescadillo_N PF06732.11 XP_668078.1 - 4e-100 334.9 1.6 4e-100 334.9 1.6 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 XP_668078.1 - 1.4e-06 28.6 0.0 3.9e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 XP_668078.1 - 1.8e-05 25.0 0.1 5.6e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 XP_668078.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain CRAL_TRIO PF00650.20 XP_668079.1 - 7e-29 100.6 0.0 1.5e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 XP_668079.1 - 3.9e-06 27.1 0.0 9.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 XP_668079.1 - 0.00057 20.0 0.2 0.0013 18.8 0.2 1.8 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain tRNA-synt_1e PF01406.19 XP_668080.1 - 3.2e-125 417.5 0.0 4e-125 417.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 XP_668080.1 - 9.8e-08 31.1 0.6 0.0079 15.0 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 XP_668080.1 - 0.00024 19.5 0.0 0.0025 16.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 XP_668080.1 - 0.0083 15.1 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) Cas_Csn2 PF09711.10 XP_668080.1 - 0.01 15.5 0.6 0.01 15.5 0.6 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) tRNA-synt_1c PF00749.21 XP_668080.1 - 0.017 14.0 0.0 0.059 12.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain SET PF00856.28 XP_668082.1 - 2.2e-07 31.4 0.2 7.3e-07 29.7 0.2 1.9 1 1 0 1 1 1 1 SET domain RRM_1 PF00076.22 XP_668083.1 - 6.3e-18 64.4 0.1 1.2e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 XP_668083.1 - 1.9e-12 47.7 2.1 3.8e-12 46.7 2.1 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PHM7_cyt PF14703.6 XP_668083.1 - 0.0063 16.8 0.2 0.011 16.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 XP_668083.1 - 0.11 12.2 0.3 0.35 10.6 0.3 1.9 1 1 0 1 1 1 0 Ribonuclease B OB domain BRAP2 PF07576.12 XP_668083.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF2852 PF11014.8 XP_668083.1 - 0.34 11.1 1.8 0.53 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) CDC27 PF09507.10 XP_668084.1 - 6.2 6.1 47.8 10 5.4 47.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PP2C PF00481.21 XP_668085.1 - 2e-13 50.6 0.2 6.7e-05 22.6 0.0 3.4 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.6 XP_668085.1 - 0.0079 15.8 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C IF4E PF01652.18 XP_668086.1 - 3.7e-32 111.3 0.6 5.9e-32 110.7 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E O-antigen_lig PF13425.6 XP_668087.1 - 0.033 13.0 0.2 0.033 13.0 0.2 2.4 2 1 0 2 2 2 0 O-antigen ligase like membrane protein OAD_gamma PF04277.13 XP_668087.1 - 3.3 8.4 0.0 3.3 8.4 0.0 3.8 3 2 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Rpr2 PF04032.16 XP_668088.1 - 3.7e-17 62.4 1.9 5.2e-17 61.9 1.9 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain NifU_N PF01592.16 XP_668089.1 - 8.6e-47 158.5 0.1 9.8e-47 158.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1077 PF06417.12 XP_668091.1 - 2e-32 111.7 0.4 2.7e-32 111.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Rtt102p PF09510.10 XP_668091.1 - 0.012 15.8 1.9 0.012 15.8 1.9 1.9 1 1 1 2 2 2 0 Rtt102p-like transcription regulator protein GP40 PF11025.8 XP_668092.1 - 1.7e-89 297.8 2.8 1.7e-89 297.8 2.8 2.3 2 0 0 2 2 2 1 Glycoprotein GP40 of Cryptosporidium Glyco_hydro_5_C PF18564.1 XP_668092.1 - 0.028 15.0 0.1 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycoside hydrolase family 5 C-terminal domain DUF4537 PF15057.6 XP_668092.1 - 0.045 13.8 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TLP-20 PF06088.11 XP_668092.1 - 0.15 12.0 2.8 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SURF2 PF05477.11 XP_668092.1 - 0.24 11.0 4.8 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Spec3 PF15795.5 XP_668093.1 - 0.0011 19.5 6.9 0.0011 19.5 6.9 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein DUF3040 PF11239.8 XP_668093.1 - 0.034 14.4 0.5 0.06 13.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DnaJ PF00226.31 XP_668094.1 - 1.2e-17 63.8 0.2 5.2e-17 61.7 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain FlaC_arch PF05377.11 XP_668094.1 - 0.08 13.4 0.2 1.5 9.3 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 XP_668097.1 - 2.3e-59 200.9 0.0 2.1e-37 129.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668097.1 - 5.6e-33 114.3 0.0 8e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 XP_668097.1 - 3.5e-30 101.3 9.5 1.1e-05 24.6 0.1 5.9 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 XP_668097.1 - 4.7e-29 100.6 0.5 3.7e-10 40.1 0.2 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 XP_668097.1 - 9.6e-26 87.5 11.8 1.9e-05 24.2 0.1 6.0 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 XP_668097.1 - 6.2e-24 82.4 14.2 0.0001 21.6 0.2 5.7 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 XP_668097.1 - 1e-21 76.5 11.3 1.1e-05 25.2 0.0 5.7 4 1 1 5 5 5 5 EF-hand domain pair Kinase-like PF14531.6 XP_668097.1 - 5.5e-06 25.9 0.3 0.11 11.8 0.1 2.8 3 0 0 3 3 3 2 Kinase-like SPARC_Ca_bdg PF10591.9 XP_668097.1 - 8.9e-06 26.0 2.7 0.088 13.1 0.0 4.4 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 XP_668097.1 - 0.00026 20.4 0.6 0.00083 18.8 0.0 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Loricrin PF15847.5 XP_668097.1 - 0.0018 17.4 12.6 0.0018 17.4 12.6 2.1 2 0 0 2 2 2 1 Major keratinocyte cell envelope protein Caleosin PF05042.13 XP_668097.1 - 0.032 14.2 0.5 26 4.7 0.0 3.7 2 1 0 3 3 3 0 Caleosin related protein EF-hand_4 PF12763.7 XP_668097.1 - 0.17 11.8 4.8 2.4 8.2 0.0 3.3 2 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand RR_TM4-6 PF06459.12 XP_668099.1 - 0.22 11.3 17.7 0.026 14.3 4.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4604 PF15377.6 XP_668099.1 - 1.8 9.0 22.5 0.032 14.7 8.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Mucin PF01456.17 XP_668099.1 - 6.7 6.7 60.7 0.51 10.3 45.4 2.4 1 1 1 2 2 2 0 Mucin-like glycoprotein PRCH PF03967.13 XP_668099.1 - 7.3 6.8 6.3 25 5.1 5.9 2.1 1 1 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Taeniidae_ag PF05596.11 XP_668101.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Taeniidae antigen Baculo_PEP_C PF04513.12 XP_668102.1 - 0.00065 19.8 14.3 0.03 14.4 6.5 3.4 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 XP_668102.1 - 0.0026 18.1 7.3 0.22 11.9 3.6 3.3 2 1 0 2 2 2 1 Syntaxin-like protein DUF1664 PF07889.12 XP_668102.1 - 0.0029 17.6 1.2 0.0029 17.6 1.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 XP_668102.1 - 0.037 14.5 14.1 0.12 12.9 0.6 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 XP_668102.1 - 0.04 14.0 0.4 0.21 11.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Laminin_II PF06009.12 XP_668102.1 - 0.05 13.6 5.7 3.9 7.5 3.0 3.3 2 1 1 3 3 3 0 Laminin Domain II Lipoprotein_2 PF00921.17 XP_668102.1 - 0.057 13.0 3.6 0.093 12.3 1.2 2.2 1 1 1 2 2 2 0 Borrelia lipoprotein CorA PF01544.18 XP_668102.1 - 0.1 11.9 3.2 0.23 10.7 3.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein COG2 PF06148.11 XP_668102.1 - 0.11 12.6 4.1 2.3 8.3 1.0 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cluap1 PF10234.9 XP_668102.1 - 0.23 10.8 4.3 0.45 9.9 4.3 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 HsbA PF12296.8 XP_668102.1 - 0.25 11.8 5.9 1.8 9.0 2.3 3.3 2 1 1 3 3 3 0 Hydrophobic surface binding protein A PhaP_Bmeg PF09602.10 XP_668102.1 - 0.43 10.5 5.9 0.38 10.7 2.3 2.4 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FidL_like PF15941.5 XP_668102.1 - 7.5 7.1 11.5 7.4 7.1 2.9 3.9 3 1 1 4 4 4 0 FidL-like putative membrane protein ATP-synt_ab PF00006.25 XP_668104.1 - 8.2e-32 110.6 0.0 1.9e-31 109.4 0.0 1.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 XP_668104.1 - 1.1e-22 80.3 0.3 2.7e-22 79.0 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 XP_668104.1 - 0.0012 18.2 0.8 0.0021 17.4 0.8 1.4 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 XP_668104.1 - 0.0091 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 XP_668104.1 - 0.017 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 XP_668104.1 - 0.018 15.4 0.1 0.043 14.2 0.1 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 XP_668104.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 XP_668104.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 XP_668104.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 XP_668104.1 - 0.24 11.8 0.4 0.49 10.7 0.4 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 XP_668104.1 - 0.25 11.8 2.0 0.87 10.1 0.2 2.5 2 1 1 3 3 3 0 ABC transporter AAA PF00004.29 XP_668105.1 - 5.5e-42 143.3 0.0 1.4e-41 142.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 XP_668105.1 - 1.4e-19 69.8 0.0 3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 XP_668105.1 - 7.1e-10 38.5 0.1 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 XP_668105.1 - 6.1e-06 26.3 1.8 4e-05 23.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 XP_668105.1 - 0.0001 22.1 0.0 0.00027 20.7 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 XP_668105.1 - 0.00015 22.2 0.9 0.0042 17.5 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain TMF_TATA_bd PF12325.8 XP_668105.1 - 0.00036 20.7 2.7 0.00036 20.7 2.7 1.9 2 0 0 2 2 1 1 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 XP_668105.1 - 0.00044 20.3 0.3 0.0014 18.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) AAA_22 PF13401.6 XP_668105.1 - 0.00077 19.7 1.2 0.087 13.1 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 XP_668105.1 - 0.00079 19.6 0.0 0.0041 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 XP_668105.1 - 0.0019 17.6 0.2 0.012 15.0 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 XP_668105.1 - 0.004 17.3 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TolA_bind_tri PF16331.5 XP_668105.1 - 0.0051 16.9 3.5 0.01 15.9 1.1 2.3 2 0 0 2 2 2 1 TolA binding protein trimerisation DUF815 PF05673.13 XP_668105.1 - 0.009 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KELK PF15796.5 XP_668105.1 - 0.011 16.2 2.0 0.031 14.7 2.0 1.8 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PhoH PF02562.16 XP_668105.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 XP_668105.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 XP_668105.1 - 0.031 14.1 0.3 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 XP_668105.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.11 XP_668105.1 - 0.042 13.9 1.5 0.078 13.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sigma54_activat PF00158.26 XP_668105.1 - 0.062 13.0 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 XP_668105.1 - 0.074 12.4 0.5 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 XP_668105.1 - 0.084 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 XP_668105.1 - 0.097 13.2 0.0 0.35 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 XP_668105.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region UPF0242 PF06785.11 XP_668105.1 - 0.11 12.6 3.5 0.18 11.9 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc24 PF08286.11 XP_668105.1 - 0.12 12.6 0.9 0.31 11.3 0.9 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ZapB PF06005.12 XP_668105.1 - 0.54 10.7 6.5 0.4 11.2 3.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB PI3_PI4_kinase PF00454.27 XP_668106.1 - 7.9e-44 150.3 0.1 2e-43 149.0 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FRG2 PF15315.6 XP_668106.1 - 0.78 9.9 6.2 1.3 9.2 6.2 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DnaJ_C PF01556.18 XP_668107.1 - 4.8e-20 72.2 0.1 6.1e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 XP_668107.1 - 0.027 14.8 0.2 0.046 14.1 0.2 1.4 1 0 0 1 1 1 0 DnaJ central domain Myosin_head PF00063.21 XP_668108.1 - 9.5e-192 638.8 8.6 2e-191 637.7 8.6 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 XP_668108.1 - 0.027 14.7 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 XP_668108.1 - 0.039 13.8 0.2 0.089 12.6 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TsaE PF02367.17 XP_668108.1 - 0.17 11.9 0.2 0.37 10.8 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 XP_668108.1 - 0.17 11.1 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin XPC-binding PF09280.11 XP_668108.1 - 0.68 9.7 4.3 3.1 7.6 0.1 3.2 3 0 0 3 3 3 0 XPC-binding domain Gln-synt_C PF00120.24 XP_668109.1 - 4.4e-105 351.5 0.0 5.4e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 XP_668109.1 - 1.1e-20 73.1 0.7 2e-20 72.3 0.7 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4359 PF14271.6 XP_668109.1 - 1.1 10.0 3.4 2.4 9.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4359) RNA_pol_Rpc34 PF05158.12 XP_668110.1 - 1.6e-41 142.8 2.8 8.6e-38 130.6 0.2 2.2 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit Ank_4 PF13637.6 XP_668111.1 - 2.3e-24 85.4 0.5 3.3e-08 33.9 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 XP_668111.1 - 1.4e-23 83.3 0.2 3.7e-12 46.7 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 XP_668111.1 - 8e-20 70.6 0.7 4e-08 33.4 0.1 4.2 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 XP_668111.1 - 4.3e-18 64.9 1.7 0.00052 20.3 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 XP_668111.1 - 8.4e-15 53.4 0.1 0.004 17.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat PIG-H PF10181.9 XP_668112.1 - 2.4e-08 33.7 0.7 1.2e-07 31.5 0.2 2.0 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Phage_holin_2_3 PF16080.5 XP_668112.1 - 0.06 13.1 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 WD40 PF00400.32 XP_668113.1 - 2e-18 66.4 11.1 0.00015 22.5 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 XP_668113.1 - 0.00032 20.6 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 XP_668113.1 - 0.00034 20.9 0.0 18 5.7 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 XP_668113.1 - 0.082 11.4 0.0 0.27 9.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_L26 PF16906.5 XP_668114.1 - 4.9e-15 55.7 0.5 6.1e-15 55.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 XP_668114.1 - 0.039 13.9 1.9 0.082 12.9 1.9 1.7 1 1 0 1 1 1 0 KOW motif Ribosomal_S8e PF01201.22 XP_668115.1 - 1.2e-52 177.7 0.2 1.4e-52 177.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Spt5-NGN PF03439.13 XP_668117.1 - 2e-18 66.1 0.0 4.8e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 XP_668117.1 - 3.8e-09 36.2 19.0 0.32 11.0 0.1 7.6 8 0 0 8 8 8 5 KOW motif DUF3449 PF11931.8 XP_668119.1 - 1.7e-64 217.0 0.3 2.4e-64 216.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-met PF12874.7 XP_668119.1 - 0.0028 18.0 4.7 0.66 10.4 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type YabA PF06156.13 XP_668119.1 - 0.057 14.1 1.2 0.17 12.6 1.2 1.8 1 0 0 1 1 1 0 Initiation control protein YabA zf-C2H2_jaz PF12171.8 XP_668119.1 - 0.77 10.1 6.8 9.9 6.6 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 XP_668119.1 - 1.4 9.9 5.2 5.6 8.1 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Rft-1 PF04506.13 XP_668120.1 - 6e-51 173.7 33.5 7.3e-51 173.5 33.5 1.0 1 0 0 1 1 1 1 Rft protein SAC3_GANP PF03399.16 XP_668121.1 - 6.1e-19 68.5 12.5 1.8e-18 67.0 6.1 3.1 2 2 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 XP_668121.1 - 0.0001 22.3 0.1 0.00031 20.8 0.1 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ABC_membrane PF00664.23 XP_668123.1 - 1.2e-89 300.6 30.8 6.3e-48 163.8 12.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 XP_668123.1 - 6e-50 169.3 0.5 4.6e-34 117.9 0.1 2.9 2 0 0 2 2 2 2 ABC transporter AAA_15 PF13175.6 XP_668123.1 - 5.4e-11 42.8 4.7 1.2e-05 25.2 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 XP_668123.1 - 1.1e-07 31.5 0.6 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 XP_668123.1 - 1.1e-07 31.5 3.7 0.0046 16.4 0.1 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 XP_668123.1 - 3.3e-07 30.4 8.1 0.019 14.8 0.1 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 XP_668123.1 - 3.7e-06 27.3 0.1 0.11 12.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 XP_668123.1 - 4.9e-06 27.0 0.0 0.095 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 XP_668123.1 - 6.8e-06 26.1 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 XP_668123.1 - 1.5e-05 25.6 5.7 0.017 15.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain G-alpha PF00503.20 XP_668123.1 - 5.5e-05 22.5 0.3 0.038 13.2 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 XP_668123.1 - 0.00017 21.7 0.0 0.042 13.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 XP_668123.1 - 0.00078 19.2 0.0 2.3 7.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 XP_668123.1 - 0.0059 16.1 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 XP_668123.1 - 0.0063 16.5 0.0 6.4 6.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 XP_668123.1 - 0.0071 16.9 0.0 0.32 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ycf70 PF17382.2 XP_668123.1 - 0.0095 16.3 0.2 0.05 14.0 0.2 2.3 1 0 0 1 1 1 1 Uncharacterized Ycf70-like DUF87 PF01935.17 XP_668123.1 - 0.011 15.8 0.4 2.6 8.1 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 XP_668123.1 - 0.014 14.5 0.0 0.069 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF417 PF04224.12 XP_668123.1 - 0.018 14.6 0.6 0.12 11.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF417 Zeta_toxin PF06414.12 XP_668123.1 - 0.035 13.4 0.0 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 XP_668123.1 - 0.059 13.3 0.2 16 5.3 0.0 3.1 4 0 0 4 4 2 0 NACHT domain PRK PF00485.18 XP_668123.1 - 0.081 12.6 0.0 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 XP_668123.1 - 0.1 13.0 0.0 18 5.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 XP_668123.1 - 0.11 12.8 0.1 25 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF1548 PF07579.11 XP_668123.1 - 0.15 12.4 1.6 8.6 6.7 0.1 3.0 3 0 0 3 3 2 0 Domain of Unknown Function (DUF1548) AAA_24 PF13479.6 XP_668123.1 - 0.42 10.3 1.7 13 5.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 XP_668124.1 - 1e-67 223.9 4.1 5.4e-15 55.0 0.0 5.8 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_668124.1 - 3.7e-08 33.0 0.1 1.3 8.7 0.0 4.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 XP_668124.1 - 3.4e-05 24.0 0.1 0.12 12.6 0.0 4.3 4 0 0 4 4 4 1 BRCA1-associated protein 2 RRM_occluded PF16842.5 XP_668124.1 - 0.0012 18.7 1.6 0.0034 17.2 0.0 2.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 XP_668124.1 - 0.0016 18.4 0.4 4.4 7.4 0.0 4.0 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 XP_668124.1 - 0.0017 18.4 1.2 3.5 7.8 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif RL PF17797.1 XP_668124.1 - 0.0047 16.9 0.1 9.5 6.2 0.0 4.1 4 0 0 4 4 4 1 RL domain Nup35_RRM_2 PF14605.6 XP_668124.1 - 0.0056 16.6 0.0 8.8 6.4 0.0 3.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TFIIE_beta PF02186.15 XP_668126.1 - 3e-05 24.2 0.2 6.7e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain Cyclin_N PF00134.23 XP_668128.1 - 2.4e-14 53.2 0.1 4.1e-10 39.5 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 XP_668128.1 - 3e-12 46.7 0.1 6.9e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain FliM PF02154.15 XP_668128.1 - 0.0063 16.4 0.2 2.9 7.7 0.0 2.5 2 1 0 2 2 2 2 Flagellar motor switch protein FliM EPL1 PF10513.9 XP_668128.1 - 0.027 14.9 1.5 0.052 13.9 1.5 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Myb_DNA-binding PF00249.31 XP_668129.1 - 0.00071 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rad1 PF02144.16 XP_668130.1 - 1.3e-06 27.8 3.2 8.7e-06 25.0 3.2 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 XP_668130.1 - 0.0053 16.2 1.3 0.0056 16.2 1.3 1.2 1 0 0 1 1 1 1 Rad9 Ribonuc_P_40 PF08584.11 XP_668131.1 - 0.0065 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Metallophos PF00149.28 XP_668132.1 - 2.1e-36 126.3 0.8 2.7e-36 126.0 0.2 1.5 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 XP_668132.1 - 0.00045 20.6 0.6 0.0011 19.4 0.6 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BpuJI_N PF11564.8 XP_668132.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Mito_carr PF00153.27 XP_668133.1 - 3.8e-46 155.0 3.0 1.5e-17 63.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box PF00646.33 XP_668134.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 F-box domain Mtc PF03820.17 XP_668136.1 - 0.04 13.0 1.5 0.091 11.8 1.4 1.6 2 0 0 2 2 2 0 Tricarboxylate carrier AAA_23 PF13476.6 XP_668137.1 - 2.8e-23 83.5 64.8 3.6e-20 73.3 36.9 4.4 1 1 1 3 3 3 1 AAA domain SMC_N PF02463.19 XP_668137.1 - 6.5e-08 32.3 0.1 6.5e-08 32.3 0.1 2.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 XP_668137.1 - 0.00021 21.0 0.1 0.0007 19.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 XP_668137.1 - 0.00021 21.7 0.2 0.00097 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 XP_668137.1 - 0.00022 21.2 0.0 0.00022 21.2 0.0 3.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 XP_668137.1 - 0.00073 19.8 1.5 0.0017 18.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 XP_668137.1 - 0.0056 16.4 58.3 0.2 11.3 48.4 2.7 1 1 1 2 2 1 1 AAA ATPase domain AKNA PF12443.8 XP_668137.1 - 0.012 16.2 0.3 0.012 16.2 0.3 3.2 4 0 0 4 4 4 0 AT-hook-containing transcription factor Zeta_toxin PF06414.12 XP_668137.1 - 0.015 14.5 0.1 0.065 12.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 XP_668137.1 - 0.081 11.6 0.0 0.081 11.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 XP_668137.1 - 0.64 10.3 0.0 0.64 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 XP_668137.1 - 1.4 9.4 20.7 34 4.9 20.2 3.3 1 1 0 1 1 1 0 ABC transporter UPF0203 PF05254.12 XP_668138.1 - 0.054 13.7 1.4 0.14 12.4 1.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) FAT PF02259.23 XP_668138.1 - 0.25 10.5 7.4 0.22 10.7 0.8 2.4 2 1 0 2 2 2 0 FAT domain DUF4763 PF15960.5 XP_668138.1 - 0.32 10.3 9.5 0.023 14.0 4.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) BRE1 PF08647.11 XP_668138.1 - 8 6.6 16.1 7.7 6.7 5.2 3.5 2 2 0 3 3 3 0 BRE1 E3 ubiquitin ligase Sua5_yciO_yrdC PF01300.18 XP_668139.1 - 1.8e-46 157.9 0.0 2.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 XP_668139.1 - 1.7e-10 41.6 0.0 3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Actin PF00022.19 XP_668140.1 - 9.8e-20 70.5 0.0 4.9e-17 61.7 0.0 2.5 1 1 1 2 2 2 2 Actin O-FucT PF10250.9 XP_668141.1 - 8.2e-52 177.0 1.3 1.1e-51 176.6 1.3 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Radical_SAM_C PF16199.5 XP_668142.1 - 1.8e-20 72.8 0.0 4.4e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 XP_668142.1 - 4.4e-10 40.2 6.7 7e-10 39.5 3.5 2.9 3 1 0 3 3 3 1 Radical SAM superfamily Terpene_synth_C PF03936.16 XP_668142.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Acetyltransf_1 PF00583.25 XP_668142.1 - 0.055 13.7 0.5 0.16 12.2 0.5 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family VirB8 PF04335.13 XP_668143.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein DUF5126 PF17166.4 XP_668143.1 - 0.32 10.9 1.9 4 7.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) PTPA PF03095.15 XP_668144.1 - 6.3e-103 344.4 0.3 7.1e-103 344.2 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Actin PF00022.19 XP_668145.1 - 3.6e-56 190.5 0.0 4.3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 XP_668145.1 - 0.00016 20.6 0.9 0.068 12.0 0.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 XP_668145.1 - 0.062 13.7 2.3 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 Cell division protein FtsA Proteasome PF00227.26 XP_668146.1 - 2.3e-14 53.3 0.5 3.1e-14 52.9 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit SRP68 PF16969.5 XP_668147.1 - 4.2e-34 118.5 12.9 4.7e-31 108.4 12.9 3.2 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 RSS_P20 PF11757.8 XP_668147.1 - 9.2 6.8 13.8 0.22 12.0 1.3 4.0 4 0 0 4 4 4 0 Suppressor of RNA silencing P21-like N-terminal domain G8 PF10162.9 XP_668148.1 - 0.16 12.1 0.0 20 5.3 0.0 2.5 3 0 0 3 3 3 0 G8 domain DNA_pol3_a_NI PF14480.6 XP_668149.1 - 0.021 14.8 0.3 0.037 14.0 0.3 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I DUF572 PF04502.13 XP_668150.1 - 2.3e-48 165.5 4.4 2.9e-48 165.2 4.4 1.2 1 1 0 1 1 1 1 Family of unknown function (DUF572) NuA4 PF09340.10 XP_668151.1 - 7.2e-20 70.6 0.1 7.2e-20 70.6 0.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF3287 PF11690.8 XP_668151.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) SLBP_RNA_bind PF15247.6 XP_668152.1 - 2.9e-18 65.7 2.9 2.9e-18 65.7 2.9 3.1 3 1 0 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain Rad4 PF03835.15 XP_668153.1 - 3.2e-17 62.6 7.1 1.8e-12 47.2 3.1 2.8 2 0 0 2 2 2 2 Rad4 transglutaminase-like domain BHD_3 PF10405.9 XP_668153.1 - 6.2e-16 58.6 0.1 1.4e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 XP_668153.1 - 2.6e-12 46.4 0.0 5.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 XP_668153.1 - 0.0045 17.9 1.8 0.016 16.2 0.3 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 XP_668153.1 - 0.091 13.2 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily UPF0004 PF00919.20 XP_668154.1 - 2.2e-18 66.1 0.3 5.8e-18 64.7 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 XP_668154.1 - 5.5e-17 62.7 0.0 1.3e-16 61.5 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily POTRA PF07244.15 XP_668155.1 - 0.0014 19.2 0.8 0.0029 18.1 0.8 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat PKD_channel PF08016.12 XP_668155.1 - 0.0063 15.2 24.5 0.014 14.1 24.5 1.5 1 0 0 1 1 1 1 Polycystin cation channel DUF1687 PF07955.11 XP_668155.1 - 0.086 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Fijivirus_P9-2 PF06837.11 XP_668155.1 - 0.17 11.3 0.0 0.17 11.3 0.0 3.6 3 0 0 3 3 3 0 Fijivirus P9-2 protein DUF3273 PF11677.8 XP_668156.1 - 1.2e-71 241.1 11.8 1.4e-71 240.9 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) EMC3_TMCO1 PF01956.16 XP_668157.1 - 8.1e-16 58.2 3.0 9.6e-16 58.0 3.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4229 PF14012.6 XP_668157.1 - 0.033 14.3 0.4 0.42 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SET PF00856.28 XP_668159.1 - 7.6e-08 32.9 0.2 7.6e-08 32.9 0.2 2.8 3 1 0 3 3 3 1 SET domain Pik1 PF11522.8 XP_668159.1 - 0.0027 17.6 0.3 0.012 15.5 0.3 2.3 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Zf_RING PF16744.5 XP_668159.1 - 0.0031 17.6 4.6 0.0031 17.6 4.6 3.5 3 0 0 3 3 3 1 KIAA1045 RING finger CooC_C PF15976.5 XP_668159.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 CS1-pili formation C-terminal VWA_N2 PF16164.5 XP_668159.1 - 0.46 10.7 9.3 0.066 13.4 4.7 2.0 2 0 0 2 2 2 0 VWA N-terminal PHD PF00628.29 XP_668159.1 - 6.2 6.8 25.6 0.062 13.2 8.2 3.4 3 0 0 3 3 3 0 PHD-finger CRAL_TRIO PF00650.20 XP_668160.1 - 2.7e-29 101.9 0.2 6e-29 100.8 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 XP_668160.1 - 8.1e-07 29.1 0.1 6e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PS_pyruv_trans PF04230.13 XP_668161.1 - 4.7e-21 75.9 2.1 4.7e-21 75.9 2.1 1.8 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase Fringe PF02434.16 XP_668161.1 - 2.1e-19 69.9 0.1 5.4e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 XP_668161.1 - 1.1e-10 41.7 0.0 3.4e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Galactosyltransferase Fez1 PF06818.15 XP_668162.1 - 0.0032 17.9 21.6 0.0032 17.9 21.6 4.3 2 1 2 4 4 4 1 Fez1 MAAL_C PF07476.11 XP_668162.1 - 0.057 12.6 1.0 0.88 8.7 0.5 2.3 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus M_domain PF12938.7 XP_668162.1 - 0.69 9.7 8.5 0.34 10.7 4.9 2.3 2 0 0 2 2 2 0 M domain of GW182 SNARE PF05739.19 XP_668163.1 - 0.019 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 SNARE domain Muskelin_N PF06588.11 XP_668163.1 - 0.059 13.3 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 Muskelin N-terminus Terminase_2 PF03592.16 XP_668164.1 - 0.013 16.0 2.4 0.015 15.8 2.4 1.1 1 0 0 1 1 1 0 Terminase small subunit CLTH PF10607.9 XP_668164.1 - 0.085 12.7 0.5 0.11 12.4 0.5 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain E2F_TDP PF02319.20 XP_668165.1 - 5.7e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Pkinase PF00069.25 XP_668166.1 - 3.7e-61 206.8 0.0 8.2e-61 205.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668166.1 - 4e-28 98.4 0.0 1.6e-27 96.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Trypan_PARP PF05887.11 XP_668166.1 - 0.023 14.7 12.4 0.043 13.8 12.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HA2 PF04408.23 XP_668167.1 - 1.6e-25 89.5 0.0 6.7e-25 87.5 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 XP_668167.1 - 3.5e-25 88.2 0.0 7.7e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 XP_668167.1 - 2.8e-12 46.9 0.0 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3885 PF13021.6 XP_668167.1 - 0.38 10.9 1.5 5.6 7.2 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3885) RRM_3 PF08777.11 XP_668168.1 - 0.067 13.2 0.1 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Hist_deacetyl PF00850.19 XP_668169.1 - 4.4e-77 259.6 0.1 5.3e-77 259.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Hus1 PF04005.12 XP_668170.1 - 1.6e-13 50.4 7.4 2.6e-13 49.7 7.4 1.3 1 1 0 1 1 1 1 Hus1-like protein Med4 PF10018.9 XP_668171.1 - 0.028 14.1 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_18 PF13238.6 XP_668172.1 - 3.2e-27 95.7 0.3 4.3e-27 95.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 XP_668172.1 - 7.4e-07 29.4 0.0 1.8e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 XP_668172.1 - 5.3e-05 22.8 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 XP_668172.1 - 8.3e-05 22.6 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 XP_668172.1 - 0.00014 22.2 0.1 0.00025 21.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 XP_668172.1 - 0.00016 22.1 0.4 0.00039 20.8 0.1 1.8 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 XP_668172.1 - 0.00017 21.9 0.3 0.00027 21.2 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 XP_668172.1 - 0.0004 20.8 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 XP_668172.1 - 0.0012 18.7 1.1 0.0034 17.1 0.4 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 XP_668172.1 - 0.0012 19.2 1.3 0.0087 16.4 0.6 2.4 1 1 0 1 1 1 1 RNA helicase AAA PF00004.29 XP_668172.1 - 0.0013 19.2 0.3 0.0028 18.1 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 XP_668172.1 - 0.0042 16.4 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.10 XP_668172.1 - 0.0058 16.1 0.5 0.031 13.7 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 XP_668172.1 - 0.0083 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 XP_668172.1 - 0.0083 15.9 0.5 0.22 11.2 0.0 2.4 2 1 0 2 2 2 1 IstB-like ATP binding protein MCM PF00493.23 XP_668172.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 XP_668172.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 XP_668172.1 - 0.012 15.8 0.1 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 XP_668172.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 XP_668172.1 - 0.015 15.4 0.0 0.12 12.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 XP_668172.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 XP_668172.1 - 0.034 14.5 0.1 0.071 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 XP_668172.1 - 0.039 13.3 0.8 1.2 8.5 0.1 2.1 1 1 1 2 2 2 0 Isopentenyl transferase RuvB_N PF05496.12 XP_668172.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 XP_668172.1 - 0.072 13.1 0.4 0.072 13.1 0.4 1.8 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 XP_668172.1 - 0.079 12.3 0.8 0.29 10.4 0.1 2.0 2 1 0 2 2 2 0 KaiC Thymidylate_kin PF02223.17 XP_668172.1 - 0.087 12.5 3.1 1.7 8.3 0.3 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_3 PF07726.11 XP_668172.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 XP_668172.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 XP_668172.1 - 0.14 12.1 0.8 0.6 10.0 0.2 2.0 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 XP_668172.1 - 0.16 12.5 0.6 0.25 11.9 0.6 1.6 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 XP_668172.1 - 0.26 11.1 4.0 4.5 7.1 0.6 2.3 1 1 1 2 2 2 0 Deoxynucleoside kinase SIT PF15330.6 XP_668174.1 - 0.014 15.9 0.9 0.016 15.6 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT NCU-G1 PF15065.6 XP_668174.1 - 0.014 14.4 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Peptidase_M56 PF05569.11 XP_668174.1 - 0.029 13.6 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Sigma_reg_N PF13800.6 XP_668174.1 - 0.13 12.6 3.5 0.42 10.9 0.2 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3377 PF11857.8 XP_668174.1 - 0.23 11.4 2.6 2.3 8.2 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Med31 PF05669.12 XP_668175.1 - 6.1e-36 122.3 5.8 7.2e-36 122.1 5.8 1.1 1 0 0 1 1 1 1 SOH1 CENP-H PF05837.12 XP_668176.1 - 0.00056 20.3 5.4 0.00056 20.3 5.4 5.3 3 1 2 5 5 5 2 Centromere protein H (CENP-H) DUF948 PF06103.11 XP_668176.1 - 1.2 9.4 11.3 6.1 7.2 1.4 3.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2d PF01409.20 XP_668177.1 - 1.1e-84 283.8 0.0 1.4e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 XP_668177.1 - 6.1e-11 41.9 0.3 1.8e-10 40.4 0.1 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 XP_668177.1 - 4.1e-09 36.6 0.4 6e-08 32.9 0.0 3.0 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 XP_668177.1 - 5.2e-06 26.0 0.0 0.0022 17.5 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 XP_668177.1 - 0.00071 18.7 0.0 0.01 14.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) S10_plectin PF03501.15 XP_668177.1 - 0.0036 17.3 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Plectin/S10 domain HTH_45 PF14947.6 XP_668177.1 - 0.063 13.3 2.0 7.3 6.7 0.3 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix Fic_N PF13784.6 XP_668178.1 - 0.14 12.2 0.3 0.38 10.8 0.3 1.7 1 0 0 1 1 1 0 Fic/DOC family N-terminal Ribosomal_L7Ae PF01248.26 XP_668179.1 - 1.4e-07 31.1 0.0 2.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ITI_HC_C PF06668.12 XP_668180.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Diphthamide_syn PF01866.17 XP_668181.1 - 3e-19 69.6 4.8 1.8e-09 37.4 1.7 2.6 2 1 0 2 2 2 2 Putative diphthamide synthesis protein DEAD PF00270.29 XP_668183.1 - 1.1e-31 109.9 0.0 2.1e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668183.1 - 1.2e-23 83.5 0.1 8.5e-23 80.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668183.1 - 1e-07 32.1 0.1 3.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RPAP1_C PF08620.10 XP_668184.1 - 1.7e-23 82.5 0.0 5e-23 81.0 0.0 1.9 1 0 0 1 1 1 1 RPAP1-like, C-terminal CPBP PF02517.16 XP_668185.1 - 6.2e-10 39.3 1.1 6.2e-10 39.3 1.1 2.3 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Enolase_N PF03952.16 XP_668186.1 - 4.8e-54 182.0 0.1 5.8e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 XP_668186.1 - 4e-13 49.3 0.3 5.5e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain PH PF00169.29 XP_668187.1 - 1.2e-19 70.8 0.4 1.5e-19 70.5 0.4 1.0 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 XP_668187.1 - 6.4e-06 26.2 0.2 1.2e-05 25.4 0.2 1.4 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 XP_668187.1 - 2.7e-05 24.4 0.1 3.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 XP_668187.1 - 0.00023 21.5 3.2 0.0025 18.2 3.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 XP_668187.1 - 0.00065 19.5 0.0 0.00098 19.0 0.0 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain Peptidase_M60 PF13402.6 XP_668189.1 - 1.2e-07 31.6 0.8 1.5e-07 31.2 0.8 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like Peptidase_M60 PF13402.6 XP_668190.1 - 2.3e-08 33.9 0.0 6.6e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 XP_668190.1 - 0.0017 18.2 0.1 0.0049 16.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases Myb_DNA-bind_7 PF15963.5 XP_668190.1 - 0.032 14.1 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Myb DNA-binding like FAST_2 PF08368.12 XP_668190.1 - 0.18 12.6 0.6 3.4 8.5 0.1 2.8 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 RIO1 PF01163.22 XP_668191.1 - 5.9e-54 182.5 0.2 2.2e-28 99.2 0.0 2.6 1 1 1 2 2 2 2 RIO1 family BRCT_2 PF16589.5 XP_668191.1 - 0.053 13.9 1.3 7.8 7.0 0.5 2.9 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF3500 PF12006.8 XP_668191.1 - 0.058 12.9 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) AAA PF00004.29 XP_668192.1 - 1.5e-83 277.8 0.0 1.7e-48 164.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 XP_668192.1 - 1.5e-20 72.7 0.0 3e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 XP_668192.1 - 3.6e-12 46.3 0.0 2.6e-05 24.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 XP_668192.1 - 1.9e-11 44.6 0.1 6.7e-05 23.3 0.0 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 XP_668192.1 - 9.5e-10 38.8 0.0 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 XP_668192.1 - 2.4e-09 37.6 0.4 0.019 15.2 0.0 5.0 3 2 2 5 5 5 2 AAA domain TIP49 PF06068.13 XP_668192.1 - 7e-09 35.3 0.0 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 XP_668192.1 - 1.4e-08 34.8 0.8 0.0055 16.7 0.1 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 XP_668192.1 - 8.8e-08 32.0 1.7 1.3 8.5 0.1 4.4 3 1 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 XP_668192.1 - 4.4e-07 29.8 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 XP_668192.1 - 1.7e-06 28.3 0.1 0.00026 21.1 0.0 3.3 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 XP_668192.1 - 5.5e-06 26.4 0.0 0.0042 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 XP_668192.1 - 7.7e-06 26.5 0.0 0.011 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 XP_668192.1 - 8.1e-06 26.2 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 XP_668192.1 - 1.8e-05 25.3 0.8 0.013 16.0 0.0 3.1 3 0 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.21 XP_668192.1 - 3.1e-05 23.4 0.9 0.027 13.9 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 XP_668192.1 - 4.4e-05 23.5 0.5 0.0036 17.2 0.0 3.3 4 0 0 4 4 4 1 Rad17 P-loop domain Zeta_toxin PF06414.12 XP_668192.1 - 5.5e-05 22.5 0.0 0.024 13.9 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.12 XP_668192.1 - 6.5e-05 22.9 0.1 0.15 12.0 0.0 3.5 4 0 0 4 4 3 1 NACHT domain TsaE PF02367.17 XP_668192.1 - 0.00021 21.3 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 XP_668192.1 - 0.00024 20.8 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 XP_668192.1 - 0.00032 20.7 0.2 0.12 12.3 0.0 3.6 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 XP_668192.1 - 0.0008 19.8 2.5 0.15 12.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 XP_668192.1 - 0.00084 19.6 0.0 0.12 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 XP_668192.1 - 0.0012 18.7 3.1 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 XP_668192.1 - 0.0012 18.3 0.6 1.3 8.4 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 XP_668192.1 - 0.0014 18.5 0.0 0.71 9.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 XP_668192.1 - 0.0014 18.0 0.7 0.59 9.4 0.0 3.6 4 0 0 4 4 4 1 KaiC AAA_24 PF13479.6 XP_668192.1 - 0.0028 17.4 0.1 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 XP_668192.1 - 0.0032 17.6 0.1 0.57 10.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 XP_668192.1 - 0.0045 16.5 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 XP_668192.1 - 0.0049 16.0 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 XP_668192.1 - 0.0056 15.9 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 XP_668192.1 - 0.016 14.9 0.1 0.1 12.3 0.0 2.2 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 XP_668192.1 - 0.025 14.3 2.0 5.7 6.6 0.0 3.3 3 1 0 3 3 3 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 XP_668192.1 - 0.036 14.2 0.1 3.3 7.8 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family SKI PF01202.22 XP_668192.1 - 0.041 14.0 0.5 2.8 8.1 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase AAA_19 PF13245.6 XP_668192.1 - 0.044 14.1 1.2 12 6.2 0.1 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 XP_668192.1 - 0.048 12.8 0.1 0.31 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 XP_668192.1 - 0.067 12.9 0.4 12 5.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 XP_668192.1 - 0.07 12.4 0.3 8.9 5.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 XP_668192.1 - 0.079 12.3 0.1 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase CAP PF00188.26 XP_668193.1 - 1.5e-18 67.8 2.5 2.9e-18 66.9 2.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PITH PF06201.13 XP_668194.1 - 3.8e-19 69.4 1.7 5.5e-19 68.9 1.7 1.2 1 0 0 1 1 1 1 PITH domain Glycos_transf_2 PF00535.26 XP_668195.1 - 1.6e-10 41.0 0.0 1.6e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 XP_668195.1 - 0.019 14.4 0.0 0.019 14.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 21 FHA PF00498.26 XP_668196.1 - 1.6e-18 66.8 0.7 4.8e-18 65.3 0.7 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 XP_668196.1 - 5.1e-09 36.3 0.0 2.1e-08 34.3 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 XP_668196.1 - 0.032 14.5 0.5 0.38 11.0 0.1 2.9 2 0 0 2 2 2 0 FHA domain PI_PP_I PF18363.1 XP_668196.1 - 0.29 11.3 3.0 0.77 10.0 0.6 2.5 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain SSP160 PF06933.11 XP_668197.1 - 0.0034 15.7 6.1 0.0048 15.2 6.1 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DEAD PF00270.29 XP_668198.1 - 3.1e-18 66.1 0.0 1e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 XP_668198.1 - 1e-12 48.4 0.7 2.3e-11 44.0 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 XP_668198.1 - 6.6e-06 26.4 0.0 4.7e-05 23.7 0.0 2.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2790 PF10976.8 XP_668198.1 - 0.0061 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2790) KIP1 PF07765.12 XP_668198.1 - 0.022 14.9 1.1 7.5 6.7 0.1 3.3 2 0 0 2 2 2 0 KIP1-like protein Nipped-B_C PF12830.7 XP_668199.1 - 7.2e-10 39.1 1.0 7.2e-10 39.1 1.0 3.7 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus PHD PF00628.29 XP_668199.1 - 7.2e-05 22.6 6.8 7.2e-05 22.6 6.8 2.8 3 0 0 3 3 3 1 PHD-finger Arm_3 PF16186.5 XP_668199.1 - 0.015 14.8 0.0 0.3 10.7 0.0 2.6 2 0 0 2 2 2 0 Atypical Arm repeat CCDC24 PF15669.5 XP_668199.1 - 0.063 13.1 0.8 0.17 11.8 0.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family HEAT PF02985.22 XP_668199.1 - 0.07 13.4 0.8 15 6.2 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat PHD_4 PF16866.5 XP_668199.1 - 4.3 7.5 10.5 0.4 10.8 3.8 2.8 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.6 XP_668199.1 - 4.5 6.9 9.2 0.15 11.6 2.1 2.2 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 XP_668199.1 - 4.7 7.2 10.7 0.19 11.7 0.8 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 XP_668199.1 - 9.1 6.5 8.8 5.3 7.2 4.8 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger Zn_Tnp_IS1595 PF12760.7 XP_668199.1 - 9.6 6.3 6.2 2.5 8.2 1.5 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FCH PF00611.23 XP_668200.1 - 3.5e-09 36.8 0.1 3.5e-09 36.8 0.1 2.6 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Amidase PF01425.21 XP_668200.1 - 1.4 7.7 4.2 1 8.3 0.4 2.2 2 1 0 2 2 2 0 Amidase Ank PF00023.30 XP_668201.1 - 2e-23 81.7 2.5 0.0014 19.0 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 XP_668201.1 - 1.3e-22 80.1 0.0 1.3e-11 44.9 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_668201.1 - 1.6e-21 76.4 0.1 5.8e-05 23.6 0.0 5.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_668201.1 - 2.6e-20 70.4 2.6 0.00054 20.2 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 XP_668201.1 - 4.2e-16 58.8 0.1 0.002 18.4 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Sushi PF00084.20 XP_668201.1 - 7e-06 26.6 1.6 1e-05 26.0 0.4 2.0 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) SWIB PF02201.18 XP_668201.1 - 0.0041 17.0 0.1 0.017 15.0 0.1 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain TMEM51 PF15345.6 XP_668201.1 - 0.085 12.7 0.1 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 MLANA PF14991.6 XP_668201.1 - 0.16 12.3 0.2 0.48 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein melan-A Plk4_PB2 PF18409.1 XP_668202.1 - 3.6 8.3 8.4 12 6.6 1.0 3.8 2 2 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Vps35 PF03635.17 XP_668203.1 - 1.4e-247 823.9 14.2 1.6e-247 823.7 14.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Npa1 PF11707.8 XP_668203.1 - 0.0076 15.6 0.1 0.0076 15.6 0.1 2.3 3 1 0 3 3 3 1 Ribosome 60S biogenesis N-terminal RTTN_N PF14726.6 XP_668203.1 - 1.1 10.1 4.8 39 5.1 0.7 4.0 3 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning Mon1 PF03164.14 XP_668204.1 - 1.4e-50 172.6 25.5 2.3e-50 171.8 25.5 1.3 1 1 0 1 1 1 1 Trafficking protein Mon1 HEAT PF02985.22 XP_668205.1 - 0.00023 21.2 0.1 2.2 8.8 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat tRNA-synt_2 PF00152.20 XP_668206.1 - 9.7e-80 268.0 0.0 1.2e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 XP_668206.1 - 6.2e-09 35.7 0.0 2e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 XP_668206.1 - 3e-06 26.9 0.1 0.034 13.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ubiquitin PF00240.23 XP_668207.1 - 1.1e-16 60.3 0.1 1.8e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 XP_668207.1 - 6.1e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 XP_668207.1 - 5.3e-05 23.0 0.0 0.00018 21.3 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 XP_668207.1 - 8.4e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 XP_668207.1 - 0.00015 22.3 0.0 0.00034 21.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.16 XP_668207.1 - 0.0013 18.4 0.6 0.0067 16.1 0.0 2.6 3 0 0 3 3 3 1 CUE domain STI1 PF17830.1 XP_668207.1 - 0.0024 17.8 21.0 0.0032 17.4 0.6 3.9 3 1 1 4 4 4 1 STI1 domain TBK1_ULD PF18396.1 XP_668207.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HOIP-UBA PF16678.5 XP_668207.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_4 PF18036.1 XP_668207.1 - 0.21 11.7 0.1 0.84 9.7 0.1 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain partial_CstF PF15861.5 XP_668207.1 - 0.35 10.7 2.4 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Partial cleavage stimulation factor domain XPC-binding PF09280.11 XP_668207.1 - 1.9 8.3 16.7 18 5.1 14.0 3.2 1 1 1 2 2 2 0 XPC-binding domain DUF4064 PF13273.6 XP_668208.1 - 0.011 16.1 11.7 2.9 8.2 5.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Cyclin PF08613.11 XP_668209.1 - 0.076 13.4 0.6 0.1 13.0 0.6 1.2 1 0 0 1 1 1 0 Cyclin Claudin_3 PF06653.11 XP_668209.1 - 0.095 12.6 2.3 0.6 10.0 2.3 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like FixS PF03597.15 XP_668209.1 - 1.3 8.7 8.3 0.22 11.3 3.8 1.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type WD40 PF00400.32 XP_668211.1 - 9.6e-19 67.4 20.3 9.4e-05 23.1 0.5 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat PFU PF09070.11 XP_668211.1 - 1.7e-17 63.7 0.1 4.8e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 XP_668211.1 - 9.8e-17 61.1 3.6 1.8e-16 60.2 3.6 1.3 1 0 0 1 1 1 1 PUL domain Met_gamma_lyase PF06838.11 XP_668212.1 - 0.018 13.6 0.1 0.024 13.2 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Lyase_catalyt PF09093.11 XP_668212.1 - 0.039 13.1 0.8 3.9 6.5 0.2 2.6 2 1 0 3 3 3 0 Lyase, catalytic CENP-F_leu_zip PF10473.9 XP_668212.1 - 0.26 11.3 8.6 0.23 11.5 2.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ThiF PF00899.21 XP_668213.1 - 5.2e-93 310.9 0.0 1.9e-63 214.1 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 XP_668213.1 - 1.7e-77 260.8 1.8 1.7e-77 260.8 1.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 XP_668213.1 - 1.1e-22 80.0 0.2 3.3e-22 78.5 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 XP_668213.1 - 1.3e-20 73.9 1.4 1.8e-20 73.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 XP_668213.1 - 8.5e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle KHA PF11834.8 XP_668214.1 - 0.036 14.2 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel adh_short PF00106.25 XP_668215.1 - 1.3e-31 109.6 0.0 1e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 XP_668215.1 - 2.6e-16 59.9 0.0 1.4e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 XP_668215.1 - 5.3e-10 39.5 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 XP_668215.1 - 0.00037 20.0 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 XP_668215.1 - 0.039 13.3 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family KleE PF17394.2 XP_668215.1 - 0.046 14.0 0.4 0.33 11.2 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein RL10P_insert PF17777.1 XP_668216.1 - 7.2e-22 77.2 0.3 1.3e-21 76.4 0.3 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 XP_668216.1 - 2.3e-19 69.4 0.1 4.8e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 XP_668216.1 - 8.6e-09 35.9 0.2 2.9e-08 34.2 0.2 2.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DFP PF04127.15 XP_668217.1 - 2.3e-13 50.4 0.0 4.7e-06 26.6 0.0 2.5 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Csm1_B PF18211.1 XP_668217.1 - 0.07 13.0 1.5 2.6 7.9 0.1 3.0 3 0 0 3 3 3 0 Csm1 subunit domain B PDT PF00800.18 XP_668218.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Prephenate dehydratase Rio2_N PF09202.11 XP_668218.1 - 0.063 13.5 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Rio2, N-terminal DUF3447 PF11929.8 XP_668219.1 - 0.95 9.5 7.1 0.29 11.1 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) dsDNA_bind PF01984.20 XP_668220.1 - 1.7e-16 60.5 0.9 1.9e-16 60.3 0.9 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3662 PF12401.8 XP_668220.1 - 0.023 15.1 0.0 0.053 13.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2662) PP2C PF00481.21 XP_668222.1 - 2.7e-54 184.5 0.1 1.5e-53 182.1 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 XP_668222.1 - 0.0086 15.7 0.0 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C KLRAQ PF10205.9 XP_668223.1 - 0.031 14.5 9.0 0.046 13.9 3.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Gon7 PF08738.10 XP_668223.1 - 0.045 13.8 0.4 0.16 12.1 0.4 2.0 1 0 0 1 1 1 0 Gon7 family DivIC PF04977.15 XP_668223.1 - 0.45 10.3 13.8 0.044 13.6 3.4 2.5 2 0 0 2 2 2 0 Septum formation initiator betaPIX_CC PF16523.5 XP_668223.1 - 2.6 7.9 7.2 6.2 6.7 1.4 2.5 2 0 0 2 2 2 0 betaPIX coiled coil NRBF2 PF08961.10 XP_668223.1 - 2.9 7.4 10.4 1.7 8.2 1.3 2.5 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 XP_668223.1 - 8.4 7.1 9.5 5.7 7.6 0.2 2.5 2 1 0 2 2 2 0 Initiation control protein YabA TSNAXIP1_N PF15739.5 XP_668224.1 - 0.51 10.7 8.6 4.9 7.6 1.0 2.8 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Tn7_Tnp_TnsA_N PF08722.11 XP_668226.1 - 0.12 12.6 0.2 0.36 11.1 0.2 1.8 1 0 0 1 1 1 0 TnsA endonuclease N terminal CTU2 PF10288.9 XP_668226.1 - 0.16 12.2 1.5 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zinc_ribbon_16 PF17034.5 XP_668226.1 - 0.51 10.6 2.9 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon like family EGF PF00008.27 XP_668227.1 - 0.031 14.6 1.3 0.047 14.0 1.3 1.5 1 1 0 1 1 1 0 EGF-like domain hEGF PF12661.7 XP_668227.1 - 0.032 14.9 2.9 0.083 13.6 2.9 1.7 1 1 0 1 1 1 0 Human growth factor-like EGF EGF_alliinase PF04863.13 XP_668227.1 - 0.85 10.1 5.1 1.6 9.2 5.1 1.7 1 1 0 1 1 1 0 Alliinase EGF-like domain Kelch_4 PF13418.6 XP_668228.1 - 1.2e-36 124.4 12.0 1.7e-06 28.0 0.0 6.7 6 2 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 XP_668228.1 - 4.8e-31 106.4 4.1 5.8e-07 29.6 0.1 7.7 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 XP_668228.1 - 2.5e-24 84.8 8.7 3.5e-06 26.9 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 XP_668228.1 - 3.8e-24 84.1 14.6 1.7e-06 28.1 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 XP_668228.1 - 3.8e-18 64.8 17.6 6e-06 25.7 0.2 6.6 6 1 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 XP_668228.1 - 7.5e-14 51.6 0.1 7.5e-14 51.6 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 XP_668228.1 - 7.8e-14 51.0 16.4 3.8e-05 23.5 0.5 6.7 6 0 0 6 6 6 5 Kelch motif Mpp10 PF04006.12 XP_668229.1 - 2e-41 142.2 44.3 2.4e-41 141.9 39.8 2.9 1 1 1 2 2 2 1 Mpp10 protein PRMT5 PF05185.16 XP_668230.1 - 3.9e-61 205.9 0.5 6e-61 205.3 0.5 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 XP_668230.1 - 1.6e-43 148.6 3.8 1.6e-43 148.6 3.8 1.8 2 0 0 2 2 2 1 PRMT5 oligomerisation domain TehB PF03848.14 XP_668230.1 - 9.7e-05 21.9 0.2 0.00017 21.1 0.2 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 XP_668230.1 - 0.00037 21.1 0.0 0.00066 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_668230.1 - 0.0049 17.6 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 XP_668230.1 - 0.023 14.3 0.1 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CTD_bind PF04818.13 XP_668231.1 - 0.0063 17.3 2.2 0.017 15.9 0.4 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CDC73_N PF16050.5 XP_668231.1 - 0.085 12.2 1.2 0.11 11.8 0.2 1.6 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal PP2C PF00481.21 XP_668232.1 - 5.6e-41 140.9 0.0 1.1e-40 140.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 XP_668232.1 - 0.00044 20.2 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) OCRE PF17780.1 XP_668232.1 - 0.04 14.0 0.2 0.089 12.8 0.2 1.6 1 0 0 1 1 1 0 OCRE domain NTP_transf_2 PF01909.23 XP_668233.1 - 1e-06 28.9 0.0 2.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 XP_668233.1 - 1.9e-05 24.8 0.2 4.2e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Carb_kinase PF01256.17 XP_668235.1 - 4.4e-48 163.9 0.0 9.6e-36 123.5 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate kinase E2F_TDP PF02319.20 XP_668236.1 - 1.7e-11 44.0 0.6 4e-11 42.8 0.6 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 XP_668236.1 - 0.00031 20.6 0.6 0.0007 19.5 0.6 1.5 1 0 0 1 1 1 1 Transcription factor DP Proteasome PF00227.26 XP_668237.1 - 1.3e-58 197.6 0.0 2.4e-58 196.8 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 XP_668237.1 - 8.6e-11 41.3 1.0 2.5e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HSP90 PF00183.18 XP_668238.1 - 1.8e-154 515.4 19.2 8.4e-148 493.5 15.8 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 XP_668238.1 - 5.5e-11 43.0 0.1 1.1e-10 42.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 XP_668238.1 - 6.3e-11 42.3 0.1 2.6e-10 40.3 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 XP_668239.1 - 3.5e-25 86.0 8.9 0.0017 18.3 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668239.1 - 1.3e-23 81.7 10.5 1.8e-07 30.6 0.1 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 XP_668239.1 - 2e-19 69.0 2.0 2.1e-06 27.3 0.0 5.5 4 2 2 6 6 5 3 TPR repeat TPR_19 PF14559.6 XP_668239.1 - 2.3e-13 50.4 0.1 0.0044 17.5 0.0 5.5 4 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 XP_668239.1 - 7.7e-13 48.5 4.7 0.00027 21.2 0.6 5.0 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668239.1 - 2.3e-12 46.1 5.1 1.1e-05 25.3 0.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 XP_668239.1 - 1e-11 45.3 0.0 0.00011 22.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 XP_668239.1 - 1.6e-10 40.9 0.0 0.021 15.6 0.2 6.0 4 2 3 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_668239.1 - 8.8e-10 38.7 19.9 1.2e-06 28.6 0.7 6.1 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 XP_668239.1 - 2.6e-08 33.7 3.3 1.1 9.8 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 XP_668239.1 - 1.2e-05 24.9 0.7 6.7 7.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 XP_668239.1 - 0.0031 18.0 0.4 32 5.4 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 XP_668239.1 - 0.0042 17.2 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 XP_668239.1 - 0.0078 16.1 1.1 8.4 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 XP_668239.1 - 0.009 16.0 5.6 1.2 9.2 0.4 3.3 3 1 1 4 4 3 2 Putative TPR-like repeat TOM20_plant PF06552.12 XP_668239.1 - 0.031 14.0 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 1 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 XP_668239.1 - 0.06 12.8 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_4 PF07721.14 XP_668239.1 - 0.069 13.8 0.0 76 4.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 XP_668239.1 - 0.1 12.0 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_15 PF13429.6 XP_668239.1 - 0.1 11.8 1.4 0.53 9.5 0.1 2.6 2 1 0 3 3 3 0 Tetratricopeptide repeat Serglycin PF04360.12 XP_668239.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Serglycin TPR_3 PF07720.12 XP_668239.1 - 0.26 11.3 1.4 15 5.7 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 XP_668239.1 - 0.96 9.6 8.2 2.2 8.4 0.2 4.3 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain Suf PF05843.14 XP_668240.1 - 0.00014 22.0 2.2 0.00014 22.0 2.2 3.5 3 2 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 XP_668240.1 - 0.00023 21.7 0.0 0.47 11.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 XP_668240.1 - 0.0003 21.2 0.0 7.3 7.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668240.1 - 0.0024 17.8 0.0 5.9 7.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 XP_668240.1 - 0.0037 17.2 22.2 4.3 7.4 0.0 7.0 7 0 0 7 7 7 3 HAT (Half-A-TPR) repeat TPR_8 PF13181.6 XP_668240.1 - 0.0042 17.2 0.1 29 5.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668240.1 - 0.042 13.7 0.0 20 5.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 XP_668240.1 - 0.055 13.5 6.7 9.5 6.2 0.0 5.6 5 2 0 5 5 5 0 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 XP_668240.1 - 0.081 13.0 20.7 0.17 11.9 1.5 6.4 2 2 3 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Baculo_IE-1 PF05290.11 XP_668241.1 - 0.017 15.1 0.6 0.023 14.6 0.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF5377 PF17347.2 XP_668241.1 - 0.069 13.5 0.7 0.15 12.5 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5377) UPF0122 PF04297.14 XP_668241.1 - 0.12 12.6 6.4 0.068 13.4 2.5 2.3 1 1 2 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like LRR_4 PF12799.7 XP_668242.1 - 9.5e-09 35.4 62.2 0.0095 16.3 0.7 10.2 7 3 5 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 XP_668242.1 - 1.5e-05 24.9 42.5 1.3 9.8 0.0 11.9 12 2 0 12 12 12 5 Leucine Rich Repeat LRR_8 PF13855.6 XP_668242.1 - 0.031 14.0 30.1 1.3 8.8 0.1 8.0 6 2 1 7 7 7 0 Leucine rich repeat RNA_pol_Rpb2_1 PF04563.15 XP_668243.1 - 7.7e-57 192.1 0.0 1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 XP_668243.1 - 7.3e-45 152.9 0.0 1.9e-44 151.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 XP_668243.1 - 1.8e-24 85.7 0.0 3.7e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 XP_668243.1 - 5.1e-20 71.8 1.9 1.2e-19 70.6 1.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 XP_668243.1 - 1.9e-19 69.7 0.1 4.8e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 polyprenyl_synt PF00348.17 XP_668244.1 - 1.7e-45 155.1 0.0 2.1e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Topoisom_I PF01028.20 XP_668245.1 - 1.7e-103 344.8 8.4 1.7e-103 344.8 8.4 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 XP_668245.1 - 5.6e-83 277.7 6.1 5.6e-83 277.7 6.1 2.8 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 XP_668245.1 - 4.1e-31 106.7 1.1 1.4e-30 105.1 1.1 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Stk19 PF10494.9 XP_668245.1 - 0.048 13.4 0.5 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 Jagunal PF07086.12 XP_668246.1 - 0.06 13.4 6.8 0.082 13.0 6.8 1.2 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis PHO4 PF01384.20 XP_668246.1 - 0.088 11.8 2.0 0.11 11.6 2.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family Tetraspanin PF00335.20 XP_668246.1 - 0.15 11.8 10.9 0.086 12.5 5.5 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF4064 PF13273.6 XP_668246.1 - 0.19 12.0 6.6 0.53 10.6 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3464 PF11947.8 XP_668246.1 - 1 9.1 7.4 0.15 11.8 1.7 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 ELMO_CED12 PF04727.13 XP_668247.1 - 3.2e-45 154.4 0.4 5.4e-45 153.7 0.4 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family FHA PF00498.26 XP_668248.1 - 3.7e-20 72.1 0.5 3.3e-13 49.8 0.4 2.8 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.6 XP_668248.1 - 3e-09 36.9 9.3 1.5e-08 34.7 9.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 XP_668248.1 - 5.3e-09 36.0 7.7 1.3e-08 34.7 5.5 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 XP_668248.1 - 8.2e-09 35.2 6.1 1.6e-08 34.3 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_668248.1 - 1.2e-08 34.7 10.1 2.6e-08 33.6 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_668248.1 - 2.3e-08 33.8 9.1 7.3e-08 32.2 9.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 XP_668248.1 - 2.5e-06 27.7 9.5 6.3e-06 26.4 9.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 XP_668248.1 - 0.00022 21.1 9.4 0.00065 19.6 9.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 XP_668248.1 - 0.00048 19.9 8.5 0.0016 18.3 8.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 XP_668248.1 - 0.00068 19.7 2.9 0.0015 18.7 2.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 XP_668248.1 - 0.04 13.8 3.6 0.1 12.5 3.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 XP_668248.1 - 0.097 12.5 8.7 0.054 13.3 3.5 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 XP_668248.1 - 1.6 9.0 8.0 9.2 6.6 8.2 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain Urm1 PF09138.11 XP_668249.1 - 6.2e-31 106.6 0.5 6.8e-31 106.5 0.5 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 XP_668249.1 - 0.0093 16.6 0.3 0.039 14.6 0.3 1.9 1 1 0 1 1 1 1 ThiS family ER_lumen_recept PF00810.18 XP_668250.1 - 9.7e-28 97.8 12.8 2.5e-27 96.5 12.8 1.7 1 1 0 1 1 1 1 ER lumen protein retaining receptor CLPTM1 PF05602.12 XP_668251.1 - 6.1e-99 331.9 14.9 7.8e-99 331.6 14.9 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 XP_668251.1 - 0.0008 19.1 3.0 0.0083 15.9 0.2 3.2 2 0 0 2 2 2 1 PQ loop repeat UbiA PF01040.18 XP_668251.1 - 0.28 10.4 8.0 0.042 13.2 3.2 2.0 2 0 0 2 2 2 0 UbiA prenyltransferase family UPF0172 PF03665.13 XP_668252.1 - 2.5e-21 76.6 0.0 6.5e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 XP_668252.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Importin_rep_4 PF18808.1 XP_668253.1 - 1.4e-15 57.4 0.5 1.4e-15 57.4 0.5 4.4 3 2 2 5 5 5 1 Importin repeat HEAT PF02985.22 XP_668253.1 - 2.1e-11 43.1 1.0 0.0012 18.9 0.0 7.4 6 0 0 6 6 5 2 HEAT repeat RIX1 PF08167.12 XP_668253.1 - 1.2e-08 34.9 3.7 0.011 15.5 0.3 6.0 5 2 0 5 5 5 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 XP_668253.1 - 1.8e-07 31.5 0.1 0.064 13.8 0.0 6.3 5 2 2 7 7 6 2 HEAT-like repeat IFRD PF05004.13 XP_668253.1 - 9.7e-07 28.2 0.2 0.00051 19.3 0.0 4.4 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 XP_668253.1 - 1.3e-06 28.6 0.0 0.0022 18.3 0.0 5.2 4 1 2 6 6 6 2 HEAT repeats Tti2 PF10521.9 XP_668253.1 - 9.3e-06 25.4 1.1 4.5 6.7 0.0 5.5 3 2 3 6 6 6 2 Tti2 family Vac14_Fab1_bd PF12755.7 XP_668253.1 - 3.1e-05 24.5 2.1 0.34 11.5 0.0 5.9 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 XP_668253.1 - 0.0037 17.1 9.9 2.2 8.2 0.0 6.7 6 2 2 8 8 8 1 UME (NUC010) domain DUF3385 PF11865.8 XP_668253.1 - 0.0047 16.9 14.5 5.6 6.9 0.0 7.1 5 2 2 8 8 8 1 Domain of unknown function (DUF3385) Arm PF00514.23 XP_668253.1 - 0.0097 15.9 0.0 3.1 8.0 0.0 4.4 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.8 XP_668253.1 - 0.01 16.4 2.4 21 5.8 0.0 5.6 7 0 0 7 7 7 0 Rix1 complex component involved in 60S ribosome maturation DUF5578 PF17741.1 XP_668253.1 - 0.062 12.7 0.1 1.9 7.9 0.0 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5578) MMS19_N PF14500.6 XP_668253.1 - 0.065 12.8 2.0 3.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II eIF-6 PF01912.18 XP_668253.1 - 0.14 11.5 0.6 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 eIF-6 family IBN_N PF03810.19 XP_668253.1 - 1.3 9.0 7.0 0.99 9.4 0.5 3.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain SWIB PF02201.18 XP_668254.1 - 3.6e-07 30.0 0.5 3.6e-07 30.0 0.5 2.5 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 XP_668254.1 - 0.0084 16.0 0.4 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain DIT1_PvcA PF05141.12 XP_668254.1 - 0.012 15.0 2.7 0.072 12.5 1.2 2.4 1 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein RRT14 PF17075.5 XP_668254.1 - 2.7 8.1 18.5 0.75 9.9 2.6 2.8 3 0 0 3 3 3 0 Regular of rDNA transcription protein 14 SLBP_RNA_bind PF15247.6 XP_668256.1 - 9.4e-21 73.7 2.6 1.1e-20 73.5 0.8 2.1 2 1 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SUR7 PF06687.12 XP_668257.1 - 0.029 14.0 0.2 0.049 13.3 0.2 1.4 1 0 0 1 1 1 0 SUR7/PalI family DUF768 PF05589.11 XP_668257.1 - 0.05 13.6 1.1 0.19 11.7 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF768) DHHC PF01529.20 XP_668259.1 - 2e-34 118.5 12.2 2e-34 118.5 12.2 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase zf-CCCH PF00642.24 XP_668260.1 - 2.1e-06 27.5 8.2 8.4e-05 22.4 0.8 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 XP_668260.1 - 0.0001 22.5 0.7 0.00023 21.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 XP_668260.1 - 0.0035 18.0 3.4 0.013 16.2 0.7 2.4 1 1 1 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 XP_668260.1 - 0.026 14.3 1.7 0.026 14.3 1.7 3.0 3 1 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 XP_668260.1 - 0.028 14.5 3.0 0.028 14.5 3.0 3.1 3 0 0 3 3 3 0 Zinc finger domain Cpn60_TCP1 PF00118.24 XP_668261.1 - 1.6e-148 495.4 7.4 1.9e-148 495.2 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Thioredoxin PF00085.20 XP_668262.1 - 8.2e-09 35.4 0.1 1.8e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 XP_668262.1 - 1e-08 34.5 1.2 1.2e-08 34.3 1.2 1.0 1 0 0 1 1 1 1 Phosducin YscO-like PF16789.5 XP_668262.1 - 0.0064 16.5 1.6 0.0081 16.2 1.6 1.2 1 0 0 1 1 1 1 YscO-like protein Skp1 PF01466.19 XP_668262.1 - 0.86 9.8 7.2 5.9 7.1 0.5 2.6 1 1 1 2 2 2 0 Skp1 family, dimerisation domain Scs3p PF10261.9 XP_668263.1 - 0.00024 20.7 2.2 0.00039 20.0 1.3 1.7 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1514 PF07438.11 XP_668263.1 - 0.66 9.9 4.6 0.18 11.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) LMBR1 PF04791.16 XP_668264.1 - 1e-66 225.9 32.6 1.3e-66 225.6 32.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein FOP_dimer PF09398.10 XP_668265.1 - 0.036 14.3 0.9 0.081 13.2 0.2 2.0 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Get5_C PF18514.1 XP_668265.1 - 0.1 12.3 0.4 8.3 6.2 0.1 2.7 2 0 0 2 2 2 0 Get5 C-terminal domain LisH_TPL PF17814.1 XP_668265.1 - 0.12 12.1 1.9 0.21 11.3 0.5 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain COPIIcoated_ERV PF07970.12 XP_668266.1 - 1.6e-57 194.9 0.5 2.2e-57 194.4 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 XP_668266.1 - 9.6e-24 83.6 4.8 4.9e-23 81.3 1.1 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Stc1 PF12898.7 XP_668266.1 - 0.053 14.1 1.1 0.1 13.2 1.1 1.5 1 0 0 1 1 1 0 Stc1 domain TPP_enzyme_N PF02776.18 XP_668267.1 - 1.5e-29 102.8 0.0 2.6e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 XP_668267.1 - 3.5e-23 81.9 0.0 8.2e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 XP_668267.1 - 3.5e-16 59.3 0.0 1.8e-15 57.1 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 XP_668267.1 - 0.0088 15.8 0.2 0.021 14.6 0.2 1.6 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit S1-P1_nuclease PF02265.16 XP_668268.1 - 4.2e-19 69.4 0.0 5.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Phospholamban PF04272.14 XP_668268.1 - 0.097 12.2 4.4 0.23 11.0 4.4 1.7 1 0 0 1 1 1 0 Phospholamban LsmAD PF06741.13 XP_668269.1 - 4.1e-13 49.7 1.8 2.7e-12 47.1 1.8 2.5 1 1 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 XP_668269.1 - 2.8e-05 24.2 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 XP_668269.1 - 0.00072 19.1 2.1 0.0015 18.1 2.1 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region NicO PF03824.16 XP_668273.1 - 0.69 9.2 8.4 0.96 8.7 8.4 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 XP_668273.1 - 1.1 8.7 25.2 1.5 8.2 25.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 XP_668273.1 - 6.2 5.9 6.8 9.3 5.4 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ER-remodelling PF14755.6 XP_668275.1 - 0.57 10.5 7.2 0.095 13.0 2.6 1.9 1 1 1 2 2 2 0 Intracellular membrane remodeller FAM60A PF15396.6 XP_668275.1 - 0.59 10.1 12.1 0.66 9.9 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 XP_668275.1 - 3 7.9 11.2 3.7 7.7 11.2 1.2 1 0 0 1 1 1 0 DDHD domain LAP1C PF05609.12 XP_668275.1 - 5.9 5.9 13.6 6.4 5.7 13.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 XP_668275.1 - 7 5.1 13.8 7.1 5.1 13.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF4175 PF13779.6 XP_668275.1 - 8.6 4.1 23.9 9.2 4.0 23.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PSI_integrin PF17205.3 XP_668277.1 - 0.0014 18.4 1.3 0.0061 16.3 1.3 2.1 1 0 0 1 1 1 1 Integrin plexin domain YkyA PF10368.9 XP_668277.1 - 0.0022 17.7 24.8 0.0022 17.7 24.8 5.5 2 1 2 5 5 5 1 Putative cell-wall binding lipoprotein DUF1601 PF07671.11 XP_668277.1 - 0.076 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Pkinase PF00069.25 XP_668279.1 - 8.4e-11 41.7 0.3 0.00057 19.3 0.2 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668279.1 - 0.031 13.6 0.1 4.5 6.5 0.1 2.5 2 1 0 2 2 2 0 Protein tyrosine kinase Clathrin_bdg PF15045.6 XP_668280.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking PseudoU_synth_1 PF01416.20 XP_668284.1 - 5.2e-29 100.9 0.0 7.6e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase Sulfate_transp PF00916.20 XP_668284.1 - 0.18 10.5 0.2 0.24 10.1 0.2 1.1 1 0 0 1 1 1 0 Sulfate permease family AA_permease_2 PF13520.6 XP_668285.1 - 3.1e-08 32.9 44.4 4.3e-08 32.4 44.4 1.2 1 0 0 1 1 1 1 Amino acid permease SRP54 PF00448.22 XP_668286.1 - 7.1e-56 188.9 0.4 1.5e-55 187.9 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 XP_668286.1 - 3.2e-08 33.9 24.6 0.00011 22.2 4.4 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 XP_668286.1 - 3.9e-07 30.2 1.0 1.9e-06 28.0 1.0 2.4 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 XP_668286.1 - 9.9e-07 28.0 0.0 2.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 XP_668286.1 - 0.0015 18.6 0.9 0.17 12.0 0.1 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 XP_668286.1 - 0.0048 16.6 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 XP_668286.1 - 0.013 15.4 1.1 0.9 9.4 0.0 3.1 4 0 0 4 4 4 0 NTPase RsgA_GTPase PF03193.16 XP_668286.1 - 0.033 14.1 0.7 2.6 7.9 0.1 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 XP_668286.1 - 0.078 13.4 0.1 0.46 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 XP_668286.1 - 0.12 12.1 0.3 3.3 7.5 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain PHD PF00628.29 XP_668287.1 - 8.8e-05 22.3 17.8 8.8e-05 22.3 17.8 2.8 2 2 1 3 3 3 1 PHD-finger zf-C2H2_6 PF13912.6 XP_668287.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CCCH PF00642.24 XP_668288.1 - 1.8e-08 34.1 15.6 1.7e-05 24.6 2.0 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 XP_668288.1 - 0.00033 20.4 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 XP_668288.1 - 0.00056 20.6 5.2 0.32 11.7 1.5 2.6 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 XP_668288.1 - 0.29 11.3 19.3 0.096 12.8 2.5 2.7 2 0 0 2 2 2 0 Zinc finger domain CENP-T_C PF15511.6 XP_668289.1 - 9.5e-09 35.4 0.2 1.1e-08 35.1 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 XP_668289.1 - 0.00018 21.7 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 XP_668289.1 - 0.00054 20.3 0.4 0.00062 20.1 0.4 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 XP_668289.1 - 0.00072 19.7 0.1 0.00098 19.3 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 XP_668289.1 - 0.0043 17.1 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 XP_668289.1 - 0.014 15.8 0.2 0.019 15.3 0.2 1.3 1 1 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 XP_668289.1 - 0.034 14.1 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 XP_668289.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Thr_dehydrat_C PF00585.18 XP_668289.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase OST3_OST6 PF04756.13 XP_668290.1 - 4.2e-31 108.4 13.0 5.4e-31 108.0 13.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF3974 PF13120.6 XP_668290.1 - 8.7 6.5 8.3 0.21 11.7 1.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3974) NADH_dehy_S2_C PF06444.11 XP_668290.1 - 9.7 6.8 12.6 0.2 12.2 0.9 3.3 3 1 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus ABC_membrane PF00664.23 XP_668292.1 - 4.8e-26 92.0 38.3 6.8e-20 71.9 16.6 3.4 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 XP_668292.1 - 1.6e-23 83.8 0.0 1.9e-10 41.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 XP_668292.1 - 8.4e-07 28.6 0.5 0.0032 17.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 XP_668292.1 - 5.4e-06 25.7 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 XP_668292.1 - 6.7e-05 22.8 1.0 0.58 9.9 0.2 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 XP_668292.1 - 0.00012 22.0 0.1 0.31 10.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 XP_668292.1 - 0.00013 21.4 0.4 0.082 12.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 XP_668292.1 - 0.00039 20.5 5.1 0.065 13.3 0.2 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 XP_668292.1 - 0.00093 19.5 4.3 0.6 10.4 0.3 3.6 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 XP_668292.1 - 0.00094 19.6 0.0 0.47 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Pox_A32 PF04665.12 XP_668292.1 - 0.0012 18.4 0.6 0.12 11.8 0.2 2.7 2 0 0 2 2 2 1 Poxvirus A32 protein NACHT PF05729.12 XP_668292.1 - 0.0017 18.3 0.2 2.6 7.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 XP_668292.1 - 0.0022 17.6 0.3 0.86 9.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 XP_668292.1 - 0.0039 17.3 3.8 0.21 11.7 0.2 3.0 3 0 0 3 3 3 1 Dynamin family IstB_IS21 PF01695.17 XP_668292.1 - 0.0049 16.6 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein MobB PF03205.14 XP_668292.1 - 0.0075 16.2 0.8 2.8 7.9 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 XP_668292.1 - 0.0076 16.0 0.3 0.82 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 XP_668292.1 - 0.01 15.4 0.0 0.51 9.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 XP_668292.1 - 0.012 15.3 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 XP_668292.1 - 0.013 14.9 1.5 1.2 8.6 0.3 2.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 XP_668292.1 - 0.014 15.5 6.0 0.95 9.5 0.3 3.2 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 XP_668292.1 - 0.016 15.4 0.1 10 6.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 XP_668292.1 - 0.036 13.7 2.3 2.6 7.6 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 XP_668292.1 - 0.081 13.3 0.0 17 5.8 0.0 3.3 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.9 XP_668292.1 - 0.09 11.7 0.1 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Microtub_bd PF16796.5 XP_668292.1 - 0.11 12.5 2.2 21 5.0 0.1 3.6 3 0 0 3 3 3 0 Microtubule binding AAA_18 PF13238.6 XP_668292.1 - 0.12 12.9 0.2 16 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 XP_668292.1 - 0.12 12.1 0.3 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 XP_668292.1 - 0.21 11.8 2.7 20 5.4 0.1 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sec1 PF00995.23 XP_668293.1 - 1.7e-05 24.3 19.4 0.0037 16.5 4.7 2.6 2 1 0 2 2 2 2 Sec1 family VPS13_C PF16909.5 XP_668294.1 - 7.9e-49 165.8 18.0 3.9e-46 157.0 8.5 4.0 3 1 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 XP_668294.1 - 4.7e-25 88.0 0.3 1.3e-23 83.3 0.1 3.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 XP_668294.1 - 5.1e-14 52.6 0.2 1.5e-09 38.1 0.0 3.0 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 XP_668294.1 - 5.7e-07 29.8 0.5 1.5e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF4667 PF15700.5 XP_668294.1 - 0.00091 19.4 6.9 0.00091 19.4 6.9 5.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4667) LRRC37AB_C PF14914.6 XP_668295.1 - 0.0057 16.6 0.0 0.0057 16.6 0.0 2.4 2 1 0 2 2 1 1 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 XP_668295.1 - 0.0099 16.7 0.0 0.0099 16.7 0.0 2.1 2 1 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 XP_668295.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.5 2 1 0 2 2 2 0 TMEM9 WBP-1 PF11669.8 XP_668295.1 - 0.12 13.0 1.5 0.34 11.5 0.0 2.4 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF5113 PF17140.4 XP_668295.1 - 0.12 12.1 0.2 0.52 10.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TMEM154 PF15102.6 XP_668295.1 - 0.12 12.2 0.2 0.12 12.2 0.2 4.3 2 1 0 3 3 2 0 TMEM154 protein family SKG6 PF08693.10 XP_668295.1 - 0.14 11.6 4.9 0.64 9.5 4.9 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMIE PF16038.5 XP_668295.1 - 0.2 11.5 0.4 0.48 10.3 0.4 1.6 1 0 0 1 1 1 0 TMIE protein MMM1 PF10296.9 XP_668295.1 - 0.29 10.1 0.0 0.29 10.1 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 SWI-SNF_Ssr4 PF08549.10 XP_668295.1 - 0.37 9.4 8.8 0.49 9.0 8.8 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Orf78 PF06024.12 XP_668295.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.1 2 1 0 2 2 1 0 Orf78 (ac78) DUF2407_C PF13373.6 XP_668295.1 - 0.75 10.0 7.0 12 6.1 7.0 2.8 1 1 0 1 1 1 0 DUF2407 C-terminal domain Glycophorin_A PF01102.18 XP_668295.1 - 0.96 9.7 0.0 0.96 9.7 0.0 3.5 2 1 0 2 2 1 0 Glycophorin A ASD2 PF08687.11 XP_668295.1 - 1.3 8.5 4.2 2.3 7.7 4.2 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Med13_C PF06333.12 XP_668295.1 - 1.6 8.0 16.8 2.5 7.3 16.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Shisa PF13908.6 XP_668295.1 - 1.6 8.9 18.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Hamartin PF04388.12 XP_668295.1 - 3.4 6.2 19.4 5.4 5.6 19.4 1.3 1 0 0 1 1 1 0 Hamartin protein Utp14 PF04615.13 XP_668295.1 - 7.2 5.1 12.8 10 4.5 12.8 1.2 1 0 0 1 1 1 0 Utp14 protein mRNA_triPase PF02940.15 XP_668296.1 - 9.9e-12 45.0 2.7 1.6e-11 44.4 2.7 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain GSHPx PF00255.19 XP_668297.1 - 3.4e-26 90.9 0.0 8.3e-26 89.7 0.1 1.6 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 XP_668297.1 - 2.7e-07 30.5 0.0 1.4e-05 25.0 0.0 2.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 XP_668297.1 - 0.0026 17.5 0.0 0.0086 15.8 0.0 1.8 1 1 0 1 1 1 1 Redoxin Aa_trans PF01490.18 XP_668298.1 - 3e-21 75.6 32.0 7.1e-17 61.2 16.2 2.6 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein Orf78 PF06024.12 XP_668298.1 - 0.0058 16.9 2.1 0.075 13.3 0.2 3.0 2 1 0 2 2 2 1 Orf78 (ac78) SieB PF14163.6 XP_668298.1 - 1.7 8.2 7.4 7.2 6.1 1.1 3.2 3 1 0 3 3 3 0 Super-infection exclusion protein B ETRAMP PF09716.10 XP_668298.1 - 1.8 8.7 0.0 1.8 8.7 0.0 3.4 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) TPT PF03151.16 XP_668300.1 - 9.7e-16 57.9 20.8 1.3e-15 57.5 20.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 XP_668300.1 - 0.0044 17.2 30.2 0.015 15.5 13.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family PAN_1 PF00024.26 XP_668301.1 - 1.4e-09 37.8 10.5 0.00016 21.5 4.2 3.3 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 XP_668301.1 - 1e-06 28.5 7.4 0.00021 21.1 0.7 3.5 3 0 0 3 3 3 2 PAN domain Prot_inhib_II PF02428.15 XP_668301.1 - 3.8 8.0 8.5 14 6.2 1.0 2.9 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family FERM_C PF09380.10 XP_668304.1 - 0.04 14.3 0.1 0.096 13.1 0.0 1.6 1 1 1 2 2 2 0 FERM C-terminal PH-like domain EF-hand_1 PF00036.32 XP_668305.1 - 0.00074 18.9 7.4 0.0015 18.0 1.6 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 XP_668305.1 - 0.0022 17.8 5.0 0.014 15.3 1.6 3.5 4 1 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 XP_668305.1 - 0.0029 18.0 8.8 0.0093 16.4 7.6 2.2 2 1 0 2 2 2 1 EF-hand domain pair Caleosin PF05042.13 XP_668305.1 - 0.056 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Caleosin related protein EF-hand_5 PF13202.6 XP_668305.1 - 0.69 9.5 7.4 3.1 7.4 2.1 2.8 2 0 0 2 2 2 0 EF hand ATP_bind_1 PF03029.17 XP_668306.1 - 1.7e-65 221.1 0.2 1.9e-65 221.0 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 XP_668306.1 - 0.0034 17.3 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 XP_668306.1 - 0.043 13.6 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 XP_668306.1 - 0.078 12.6 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 XP_668306.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 XP_668306.1 - 0.14 11.3 0.1 0.98 8.5 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase Dor1 PF04124.12 XP_668307.1 - 0.0084 14.8 0.2 0.0094 14.7 0.2 1.2 1 0 0 1 1 1 1 Dor1-like family Vinculin PF01044.19 XP_668307.1 - 0.021 13.1 0.1 0.024 12.9 0.1 1.0 1 0 0 1 1 1 0 Vinculin family THP2 PF09432.10 XP_668308.1 - 0.0053 16.8 1.5 0.1 12.6 0.1 2.7 1 1 2 3 3 3 1 Tho complex subunit THP2 FliT PF05400.13 XP_668308.1 - 0.0065 17.3 0.8 7.8 7.4 0.0 3.0 2 1 1 3 3 3 1 Flagellar protein FliT DUF2203 PF09969.9 XP_668308.1 - 0.0067 17.1 0.3 23 5.7 0.0 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CCDC-167 PF15188.6 XP_668308.1 - 0.01 16.1 1.1 0.099 13.0 0.1 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 GLE1 PF07817.13 XP_668308.1 - 0.012 14.8 4.2 0.12 11.6 0.2 2.5 2 1 0 2 2 2 0 GLE1-like protein COG2 PF06148.11 XP_668308.1 - 0.02 15.0 4.1 0.31 11.1 0.3 3.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Helicase_Sgs1 PF11408.8 XP_668308.1 - 0.052 13.6 0.0 6.2 6.9 0.0 2.6 1 1 0 2 2 2 0 Sgs1 RecQ helicase TSNAXIP1_N PF15739.5 XP_668308.1 - 0.14 12.6 5.4 0.24 11.8 0.6 2.5 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4407 PF14362.6 XP_668308.1 - 0.14 11.5 2.0 0.51 9.6 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 XP_668308.1 - 0.15 12.6 4.9 1.2 9.6 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 HMMR_N PF15905.5 XP_668308.1 - 0.32 10.4 7.1 0.23 10.9 2.2 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 XP_668308.1 - 0.32 11.2 5.1 26 5.0 0.0 3.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 XP_668308.1 - 0.78 9.8 5.2 58 3.7 5.2 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Synaptobrevin PF00957.21 XP_668308.1 - 1.3 8.9 3.9 1.2 9.0 0.1 2.6 3 0 0 3 3 3 0 Synaptobrevin TRAF_BIRC3_bd PF16673.5 XP_668308.1 - 3.3 7.6 8.7 34 4.3 0.9 3.4 3 1 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain ING PF12998.7 XP_668308.1 - 3.8 8.1 6.9 7.3 7.3 0.1 3.1 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Cpn60_TCP1 PF00118.24 XP_668309.1 - 1.7e-145 485.5 14.7 2e-145 485.2 14.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LETM1 PF07766.13 XP_668310.1 - 7.1e-49 166.5 6.9 8.3e-49 166.3 6.9 1.0 1 0 0 1 1 1 1 LETM1-like protein Las1 PF04031.13 XP_668311.1 - 1e-32 113.4 0.0 4.7e-32 111.2 0.0 2.2 1 0 0 1 1 1 1 Las1-like Trm5_N PF18093.1 XP_668311.1 - 0.44 10.5 3.5 0.28 11.1 0.7 2.2 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Gpi1 PF05024.15 XP_668312.1 - 4.2e-38 131.3 20.2 4.2e-38 131.3 20.2 3.3 2 2 1 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) NUC153 PF08159.12 XP_668313.1 - 0.24 11.3 5.4 0.44 10.4 2.6 2.5 2 0 0 2 2 2 0 NUC153 domain Alba PF01918.21 XP_668315.1 - 4.2e-07 29.7 0.2 5.7e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Alba Proteasome PF00227.26 XP_668316.1 - 5.4e-39 133.6 0.2 7.3e-39 133.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit ATP-sulfurylase PF01747.17 XP_668316.1 - 0.035 13.6 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 ATP-sulfurylase DUF5089 PF17002.5 XP_668317.1 - 0.002 18.0 15.6 0.0056 16.6 15.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) Dynamitin PF04912.14 XP_668317.1 - 0.0081 15.5 0.8 0.0081 15.5 0.8 2.2 2 0 0 2 2 2 1 Dynamitin NPV_P10 PF05531.12 XP_668317.1 - 0.013 15.9 7.5 0.078 13.5 1.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.13 XP_668317.1 - 0.021 14.8 1.2 0.021 14.8 1.2 2.2 2 0 0 2 2 2 0 Sec20 XhlA PF10779.9 XP_668317.1 - 0.078 13.2 0.4 0.078 13.2 0.4 3.4 3 1 0 3 3 3 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 XP_668317.1 - 0.56 10.2 11.3 2 8.5 2.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.12 XP_668317.1 - 0.64 9.6 10.5 0.17 11.5 7.1 1.7 2 0 0 2 2 2 0 PspA/IM30 family DUF4407 PF14362.6 XP_668317.1 - 0.68 9.2 7.3 0.69 9.2 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAT PF03127.14 XP_668317.1 - 0.77 10.1 9.1 0.69 10.3 3.7 2.7 2 1 0 2 2 2 0 GAT domain DUF1664 PF07889.12 XP_668317.1 - 0.82 9.7 10.4 6.1 6.9 0.3 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 XP_668317.1 - 1.4 8.1 9.8 0.67 9.1 2.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein MCPsignal PF00015.21 XP_668317.1 - 1.6 8.5 7.0 7.9 6.3 2.0 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Muted PF14942.6 XP_668317.1 - 2.4 8.5 18.4 2.5 8.4 7.8 2.5 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein YtxH PF12732.7 XP_668317.1 - 2.4 8.7 5.8 29 5.3 3.4 2.7 2 1 0 2 2 2 0 YtxH-like protein UPF0242 PF06785.11 XP_668317.1 - 2.7 8.0 17.0 1.9 8.6 9.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sin3_corepress PF08295.12 XP_668317.1 - 3 8.0 6.9 0.28 11.3 1.6 2.0 3 0 0 3 3 3 0 Sin3 family co-repressor DUF948 PF06103.11 XP_668317.1 - 3.3 8.0 7.7 14 6.1 0.6 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 XP_668317.1 - 3.6 7.8 15.7 1.8 8.7 0.8 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PRD PF00874.20 XP_668317.1 - 4.5 7.6 10.6 0.67 10.3 0.2 3.4 1 1 3 4 4 4 0 PRD domain HOOK PF05622.12 XP_668317.1 - 6.7 4.7 17.5 0.048 11.8 7.7 1.9 2 0 0 2 2 2 0 HOOK protein Uds1 PF15456.6 XP_668317.1 - 6.8 6.9 10.0 2 8.6 5.3 2.3 2 2 0 2 2 2 0 Up-regulated During Septation Isy1 PF06246.12 XP_668319.1 - 7.3e-23 81.4 3.4 8.3e-23 81.3 3.4 1.0 1 0 0 1 1 1 1 Isy1-like splicing family SpoVIF PF14069.6 XP_668319.1 - 0.0027 17.5 0.5 0.0071 16.1 0.1 1.9 2 0 0 2 2 2 1 Stage VI sporulation protein F NFACT-R_1 PF05670.13 XP_668320.1 - 2.3e-32 111.9 0.0 8.5e-32 110.0 0.0 2.1 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 XP_668320.1 - 3.9e-16 58.9 0.0 3.9e-16 58.9 0.0 3.4 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 XP_668320.1 - 2.1e-13 50.1 2.3 3e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 NFACT protein C-terminal domain Ras PF00071.22 XP_668321.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Peptidase_C57 PF03290.13 XP_668321.1 - 0.00058 18.7 0.7 0.00073 18.4 0.7 1.1 1 0 0 1 1 1 1 Vaccinia virus I7 processing peptidase Gar1 PF04410.14 XP_668322.1 - 8.6e-36 123.0 0.1 1.1e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region HORMA PF02301.18 XP_668323.1 - 1.4e-61 207.8 0.3 1.4e-61 207.8 0.3 2.0 2 0 0 2 2 2 1 HORMA domain CVNH PF08881.10 XP_668323.1 - 0.032 14.9 0.1 0.15 12.8 0.0 2.0 2 1 0 2 2 2 0 CVNH domain PRP3 PF08572.10 XP_668324.1 - 4.1e-38 131.3 4.4 4.1e-38 131.3 4.4 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 XP_668324.1 - 6.3e-26 91.2 7.7 1e-25 90.6 0.4 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) Methyltr_RsmB-F PF01189.17 XP_668325.1 - 2.3e-17 63.3 0.3 3.8e-17 62.6 0.3 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F s48_45 PF07422.13 XP_668325.1 - 0.76 10.4 9.0 0.21 12.2 5.4 1.8 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain DUF2556 PF10831.8 XP_668326.1 - 0.2 11.6 1.9 0.37 10.8 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2556) CTP_synth_N PF06418.14 XP_668327.1 - 3.5e-107 357.7 0.2 5.1e-107 357.1 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 XP_668327.1 - 4.3e-44 150.6 0.0 1.3e-43 149.0 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 XP_668327.1 - 0.0093 15.7 0.3 0.96 9.2 0.1 2.8 3 0 0 3 3 3 1 Peptidase C26 CbiA PF01656.23 XP_668327.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 XP_668327.1 - 0.066 12.2 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PTN_MK_C PF01091.18 XP_668329.1 - 3.5 8.1 6.2 9.1 6.8 1.1 2.7 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain WD40 PF00400.32 XP_668330.1 - 1.5e-05 25.6 5.4 0.11 13.4 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Bromodomain PF00439.25 XP_668330.1 - 1.7e-05 24.8 0.5 7.3e-05 22.8 0.5 2.1 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H_2 PF13832.6 XP_668330.1 - 3.4e-05 24.0 1.0 0.00014 22.0 1.0 2.0 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 XP_668330.1 - 4.2e-05 23.7 7.3 0.00017 21.8 5.5 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain DUF4982 PF16355.5 XP_668331.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) MFS_1 PF07690.16 XP_668332.1 - 0.00046 19.2 36.4 0.00046 19.2 36.4 3.6 2 1 1 3 3 3 1 Major Facilitator Superfamily Mito_carr PF00153.27 XP_668333.1 - 3.1e-29 100.7 6.2 4.5e-14 52.1 0.3 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 XP_668334.1 - 8.3e-07 28.8 0.0 6.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Sec1 PF00995.23 XP_668335.1 - 1.8e-77 261.9 8.0 2.2e-77 261.6 8.0 1.1 1 0 0 1 1 1 1 Sec1 family NLRC4_HD PF17889.1 XP_668335.1 - 0.24 11.8 6.3 2 8.8 0.1 3.9 4 0 0 4 4 4 0 NLRC4 helical domain mRNA_cap_enzyme PF01331.19 XP_668336.1 - 6e-25 88.2 0.0 8.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 XP_668336.1 - 1.5e-14 54.5 0.0 3.6e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Topoisom_bac PF01131.20 XP_668337.1 - 2.2e-57 195.0 0.0 2.8e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-Sec23_Sec24 PF04810.15 XP_668337.1 - 0.038 14.1 2.0 0.038 14.1 2.0 4.7 4 1 1 5 5 5 0 Sec23/Sec24 zinc finger PuR_N PF09182.10 XP_668337.1 - 0.088 12.8 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal CutA1 PF03091.15 XP_668338.1 - 1.9e-33 114.2 1.2 2.2e-33 114.0 1.2 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein SRR1 PF07985.12 XP_668339.1 - 1.1e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 SRR1 NAC PF01849.18 XP_668340.1 - 2.5e-16 59.4 0.0 5.7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 NAC domain STI1 PF17830.1 XP_668340.1 - 0.0035 17.2 0.3 0.01 15.8 0.3 1.8 1 0 0 1 1 1 1 STI1 domain Phosphorylase PF00343.20 XP_668342.1 - 1.1e-298 992.5 0.0 1.2e-298 992.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TIG_plexin PF17960.1 XP_668342.1 - 0.05 13.6 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 TIG domain DUF4994 PF16385.5 XP_668342.1 - 0.14 12.1 0.2 0.35 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_L21e PF01157.18 XP_668343.1 - 1.2e-43 147.1 1.9 1.5e-43 146.7 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.13 XP_668343.1 - 0.022 13.2 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain SepSecS PF05889.13 XP_668343.1 - 0.1 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SAM_2 PF07647.17 XP_668343.1 - 0.2 11.8 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Evr1_Alr PF04777.13 XP_668344.1 - 8.3e-11 42.3 0.1 2.7e-10 40.6 0.1 1.9 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 XP_668344.1 - 7.8e-07 29.0 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 XP_668344.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 AhpC/TSA family zinc_ribbon_10 PF10058.9 XP_668344.1 - 8.4 6.2 6.6 8.2 6.2 0.4 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NOT2_3_5 PF04153.18 XP_668345.1 - 1e-18 67.7 3.1 1e-18 67.7 3.1 2.6 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family HECT PF00632.25 XP_668346.1 - 3.2e-87 292.9 0.6 5.4e-87 292.1 0.1 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Goodbye PF17109.5 XP_668347.1 - 6.8 7.2 15.1 3.4 8.1 0.0 5.1 5 0 0 5 5 5 0 fungal STAND N-terminal Goodbye domain PPTA PF01239.22 XP_668348.1 - 2.8e-27 93.6 20.9 2.4e-08 33.4 0.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat FKBP_C PF00254.28 XP_668351.1 - 6.2e-25 87.4 0.3 2.6e-24 85.3 0.0 2.1 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase cwf18 PF08315.12 XP_668351.1 - 0.24 12.1 3.4 0.35 11.5 3.4 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Ras PF00071.22 XP_668352.1 - 1e-50 171.5 0.0 1.2e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 XP_668352.1 - 2.1e-31 108.6 0.0 5.5e-31 107.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 XP_668352.1 - 3.2e-12 46.3 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 XP_668352.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 XP_668352.1 - 0.00098 19.5 0.3 0.013 15.9 0.2 2.4 1 1 1 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 XP_668352.1 - 0.0012 18.8 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 XP_668352.1 - 0.0077 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 XP_668352.1 - 0.0094 15.5 0.6 0.086 12.4 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 XP_668352.1 - 0.016 15.4 0.1 0.029 14.6 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 XP_668352.1 - 0.023 15.1 0.1 0.045 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 XP_668352.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 XP_668352.1 - 0.025 15.1 0.1 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter FixO PF02433.15 XP_668352.1 - 0.064 12.7 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO G-alpha PF00503.20 XP_668352.1 - 0.075 12.2 0.1 7.2 5.7 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 XP_668352.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 XP_668352.1 - 0.14 11.9 0.1 0.23 11.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 XP_668352.1 - 0.18 12.0 0.1 0.68 10.2 0.0 1.9 3 0 0 3 3 3 0 AAA domain RNase_PH PF01138.21 XP_668353.1 - 8.3e-08 32.8 0.1 1.5e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 XP_668353.1 - 0.0021 18.1 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3073 PF11273.8 XP_668354.1 - 2.1 9.1 7.9 13 6.6 7.9 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) UTP25 PF06862.12 XP_668355.1 - 2.1e-106 356.5 0.0 5.7e-106 355.1 0.0 1.6 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 VIT1 PF01988.19 XP_668356.1 - 3.4e-38 131.7 0.1 3.9e-38 131.5 0.1 1.0 1 0 0 1 1 1 1 VIT family Amino_oxidase PF01593.24 XP_668357.1 - 6.5e-25 88.3 0.0 3.8e-09 36.4 0.0 3.3 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 XP_668357.1 - 2.2e-07 31.0 0.0 5.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 XP_668357.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 XP_668357.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 XP_668357.1 - 0.00021 20.6 0.0 0.00053 19.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 XP_668357.1 - 0.0017 17.1 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 XP_668357.1 - 0.0021 17.3 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 XP_668357.1 - 0.003 16.7 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 XP_668357.1 - 0.0043 16.3 0.1 0.007 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 XP_668357.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 XP_668357.1 - 0.045 14.3 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 XP_668357.1 - 0.071 12.2 0.2 0.15 11.1 0.1 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 XP_668357.1 - 0.079 12.9 0.0 0.36 10.8 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 XP_668357.1 - 0.092 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 XP_668357.1 - 0.21 11.5 0.0 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 XP_668358.1 - 4.9e-60 203.1 0.0 6.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668358.1 - 1.2e-31 110.0 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_668358.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Rad21_Rec8_N PF04825.13 XP_668359.1 - 8.1e-17 61.4 0.2 2.4e-16 59.9 0.2 1.8 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 XP_668359.1 - 1.2e-06 27.7 0.0 4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 XP_668359.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation protein ScpA LCCL PF03815.19 XP_668360.1 - 5.9e-19 68.0 0.1 5.9e-19 68.0 0.1 3.2 3 0 0 3 3 3 1 LCCL domain F5_F8_type_C PF00754.25 XP_668360.1 - 7.8e-07 29.3 0.7 2e-06 27.9 0.7 1.7 1 0 0 1 1 1 1 F5/8 type C domain DUF1080 PF06439.11 XP_668360.1 - 7.2e-05 23.0 1.4 0.0014 18.7 0.0 3.0 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) Rxt3 PF08642.10 XP_668360.1 - 0.11 13.3 0.1 0.72 10.6 0.1 2.2 1 1 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF3108 PF11306.8 XP_668360.1 - 0.14 12.1 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) GLE1 PF07817.13 XP_668361.1 - 5.4e-22 78.2 0.2 5.4e-22 78.2 0.2 2.5 2 1 0 2 2 2 1 GLE1-like protein AF2331-like PF14556.6 XP_668361.1 - 0.068 13.7 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 AF2331-like eIF3_subunit PF08597.10 XP_668361.1 - 0.21 11.5 37.7 0.48 10.3 37.7 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3523 PF12037.8 XP_668361.1 - 3 7.1 38.4 4.6 6.5 38.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Ribosomal_L18A PF01775.17 XP_668362.1 - 4.2e-49 165.7 1.2 5.2e-49 165.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A EMP70 PF02990.16 XP_668363.1 - 7.4e-114 381.2 29.2 7.4e-114 381.2 29.2 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 GBV-C_env PF12786.7 XP_668363.1 - 0.26 9.9 0.7 0.42 9.2 0.7 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope GRASP55_65 PF04495.14 XP_668364.1 - 2.8e-33 115.1 0.0 8.6e-27 94.1 0.0 2.3 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 XP_668364.1 - 0.0032 17.8 0.2 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 XP_668364.1 - 0.0035 17.6 0.0 1.1 9.7 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 XP_668364.1 - 0.11 12.4 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 PDZ domain HSP70 PF00012.20 XP_668366.1 - 1.1e-164 549.0 9.5 1.3e-164 548.8 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 XP_668366.1 - 1.4e-06 27.4 0.2 2.8e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FIVAR PF07554.13 XP_668366.1 - 0.042 14.6 1.5 0.24 12.2 0.1 2.7 3 0 0 3 3 3 0 FIVAR domain HD_5 PF13487.6 XP_668366.1 - 0.18 12.1 0.2 30 4.9 0.0 3.4 3 1 0 3 3 3 0 HD domain Phospholip_B PF04916.13 XP_668366.1 - 0.21 10.1 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B Effector_1 PF04518.12 XP_668366.1 - 0.47 9.5 5.1 0.78 8.8 0.2 2.1 2 0 0 2 2 2 0 Effector from type III secretion system DUF357 PF04010.13 XP_668366.1 - 0.51 10.5 1.7 11 6.2 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF357) StbA PF06406.11 XP_668366.1 - 0.53 9.5 4.0 0.52 9.5 0.6 2.5 2 1 0 2 2 2 0 StbA protein Cytochrom_B562 PF07361.11 XP_668366.1 - 0.64 10.7 9.0 2.8 8.6 5.0 2.6 2 0 0 2 2 2 0 Cytochrome b562 VSG_B PF13206.6 XP_668366.1 - 1.1 8.5 6.5 0.16 11.2 2.2 1.7 2 0 0 2 2 2 0 Trypanosomal VSG domain CREPT PF16566.5 XP_668366.1 - 1.2 9.2 7.9 0.54 10.4 3.7 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ISG65-75 PF11727.8 XP_668366.1 - 4.3 6.5 8.6 0.5 9.5 3.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein EF-hand_7 PF13499.6 XP_668366.1 - 7.2 7.1 8.5 3 8.4 1.0 3.2 2 2 1 3 3 3 0 EF-hand domain pair HIP1_clath_bdg PF16515.5 XP_668366.1 - 9.8 6.9 14.1 22 5.7 0.6 3.1 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Hydrolase_4 PF12146.8 XP_668367.1 - 4.9e-13 48.9 0.0 1.5e-08 34.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 XP_668367.1 - 1.3e-08 34.8 0.0 3.3e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 XP_668367.1 - 2.2e-06 27.5 0.4 0.0037 16.9 0.2 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 XP_668367.1 - 1.1e-05 25.2 0.0 3.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 XP_668367.1 - 5e-05 22.1 0.1 0.00012 20.9 0.1 1.5 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 XP_668367.1 - 0.00024 21.8 0.0 0.00035 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 XP_668367.1 - 0.046 12.2 0.0 0.28 9.6 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 XP_668367.1 - 0.057 12.1 0.0 0.3 9.7 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 XP_668367.1 - 0.087 12.7 0.0 0.42 10.5 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AAA_18 PF13238.6 XP_668369.1 - 8.7e-06 26.3 1.0 3e-05 24.6 0.3 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 XP_668369.1 - 2.5e-05 23.6 0.0 9.8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 XP_668369.1 - 0.00017 21.8 0.1 0.0003 21.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 XP_668369.1 - 0.00049 19.9 1.0 0.0017 18.1 1.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 XP_668369.1 - 0.0032 17.9 0.1 0.0075 16.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 XP_668369.1 - 0.0038 16.9 0.4 0.013 15.2 0.3 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain CbiA PF01656.23 XP_668369.1 - 0.0047 17.0 0.2 0.012 15.7 0.2 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 XP_668369.1 - 0.0049 16.7 4.5 0.0049 16.7 4.5 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 XP_668369.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin PF02224.18 XP_668369.1 - 0.0082 15.9 1.1 0.028 14.2 1.1 2.1 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 XP_668369.1 - 0.011 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 XP_668369.1 - 0.027 14.9 0.0 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 XP_668369.1 - 0.033 14.7 1.2 0.066 13.7 1.2 1.7 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 XP_668369.1 - 0.046 13.9 0.6 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family RsgA_GTPase PF03193.16 XP_668369.1 - 0.049 13.5 0.3 0.14 12.1 0.2 1.7 1 1 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 XP_668369.1 - 0.05 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 XP_668369.1 - 0.06 13.3 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 XP_668369.1 - 0.066 13.5 0.7 0.25 11.6 0.7 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_E_2 PF08112.11 XP_668369.1 - 0.097 13.0 4.6 1.1 9.6 0.3 3.2 3 0 0 3 3 2 0 ATP synthase epsilon subunit CoaE PF01121.20 XP_668369.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase SRP54 PF00448.22 XP_668369.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CPT PF07931.12 XP_668369.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 XP_668369.1 - 0.15 11.1 1.2 0.41 9.7 0.5 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 XP_668369.1 - 0.17 12.3 3.7 0.25 11.8 1.5 2.5 2 2 1 3 3 2 0 RNA helicase NTPase_1 PF03266.15 XP_668369.1 - 0.43 10.5 2.9 4.5 7.2 0.3 2.5 1 1 1 2 2 2 0 NTPase BORCS7 PF16088.5 XP_668369.1 - 1.8 8.8 5.9 13 6.1 0.1 3.1 3 1 0 4 4 2 0 BLOC-1-related complex sub-unit 7 OST-HTH PF12872.7 XP_668371.1 - 0.00023 20.9 0.2 0.00038 20.2 0.2 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Ubie_methyltran PF01209.18 XP_668372.1 - 1.6e-32 112.7 0.8 2.1e-32 112.3 0.8 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 XP_668372.1 - 1.9e-07 31.7 0.0 3.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_668372.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_668372.1 - 0.0045 17.7 0.2 0.013 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain GSH-S_ATP PF02955.16 XP_668372.1 - 0.033 13.6 0.2 0.058 12.8 0.2 1.5 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DREV PF05219.12 XP_668372.1 - 0.043 12.9 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FlgD_ig PF13860.6 XP_668372.1 - 0.048 13.5 0.1 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 FlgD Ig-like domain DUF5037 PF16440.5 XP_668372.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5037) Pkinase PF00069.25 XP_668373.1 - 4.8e-46 157.3 0.0 9.9e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668373.1 - 1.9e-30 106.0 0.0 4.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 XP_668373.1 - 4.2e-07 29.6 0.0 7.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 XP_668373.1 - 0.077 12.6 0.5 0.88 9.1 0.1 2.3 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 XP_668373.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 XP_668373.1 - 1.4 7.6 6.5 0.42 9.3 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase CPSF_A PF03178.15 XP_668374.1 - 7.5e-31 107.6 1.7 2.1e-22 79.9 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.9 XP_668374.1 - 1.6e-23 83.2 0.4 3.4e-21 75.4 1.1 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term SNARE PF05739.19 XP_668375.1 - 2.1e-13 50.0 0.1 5.7e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 XP_668375.1 - 6.6e-06 24.4 8.5 0.0022 16.1 0.4 2.1 2 0 0 2 2 2 2 Prominin Syntaxin PF00804.25 XP_668375.1 - 2.1e-05 24.3 9.7 0.025 14.3 3.4 2.3 2 0 0 2 2 2 2 Syntaxin DUF5082 PF16888.5 XP_668375.1 - 0.0037 17.5 10.1 0.074 13.3 4.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) AI-2E_transport PF01594.16 XP_668375.1 - 0.0045 16.2 5.3 0.014 14.6 0.3 2.5 2 1 0 2 2 2 1 AI-2E family transporter KxDL PF10241.9 XP_668375.1 - 0.0048 17.2 11.2 0.017 15.4 2.0 3.1 2 1 1 3 3 3 1 Uncharacterized conserved protein Syntaxin_2 PF14523.6 XP_668375.1 - 0.01 16.2 10.1 0.066 13.6 6.7 2.7 2 1 0 2 2 2 0 Syntaxin-like protein FAM184 PF15665.5 XP_668375.1 - 0.016 15.0 0.9 0.016 15.0 0.9 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B SH3BP5 PF05276.14 XP_668375.1 - 0.018 14.9 3.5 0.23 11.2 0.4 2.4 2 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Corona_S2 PF01601.16 XP_668375.1 - 0.019 13.5 8.0 0.066 11.7 2.0 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Lipoprotein_7 PF01540.16 XP_668375.1 - 0.037 13.3 1.8 0.33 10.2 0.2 2.6 3 0 0 3 3 3 0 Adhesin lipoprotein Syntaxin-6_N PF09177.11 XP_668375.1 - 0.043 14.4 5.2 1.9 9.1 2.5 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CcdA PF07362.12 XP_668375.1 - 0.051 14.0 0.5 1 9.8 0.0 2.8 3 0 0 3 3 2 0 Post-segregation antitoxin CcdA Goodbye PF17109.5 XP_668375.1 - 0.058 13.8 1.9 1.2 9.5 0.1 2.6 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Vac_Fusion PF02346.16 XP_668375.1 - 0.14 11.8 3.0 2.2 8.0 0.0 3.5 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF3456 PF11938.8 XP_668375.1 - 0.58 10.7 3.0 22 5.5 0.4 2.4 2 1 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Laminin_II PF06009.12 XP_668375.1 - 0.67 10.0 5.4 1.9 8.5 1.4 2.4 2 0 0 2 2 2 0 Laminin Domain II MCPsignal PF00015.21 XP_668375.1 - 0.76 9.6 7.8 1.2 8.9 0.9 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tweety PF04906.13 XP_668375.1 - 0.86 8.2 3.9 12 4.5 0.2 2.4 2 1 0 2 2 2 0 Tweety DUF948 PF06103.11 XP_668375.1 - 1.1 9.6 9.1 20 5.5 0.1 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 XP_668375.1 - 1.1 9.1 7.7 2.5 7.9 2.3 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain CLZ PF16526.5 XP_668375.1 - 1.3 9.5 8.5 2.6 8.4 0.3 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 XP_668375.1 - 2.4 8.2 11.1 1.8 8.6 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 XP_668375.1 - 2.7 7.5 11.0 0.25 10.9 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DNA_repr_REX1B PF14966.6 XP_668375.1 - 3 8.6 8.4 1.1 10.0 0.8 3.1 2 1 1 3 3 3 0 DNA repair REX1-B DASH_Dad1 PF08649.10 XP_668375.1 - 3.8 7.8 10.0 5 7.4 0.6 3.4 3 1 0 3 3 3 0 DASH complex subunit Dad1 Tup_N PF08581.10 XP_668375.1 - 4.1 7.8 10.8 0.45 10.9 2.4 2.8 2 1 0 2 2 2 0 Tup N-terminal BLOC1_2 PF10046.9 XP_668375.1 - 9.2 6.7 12.3 6.3 7.2 2.6 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 XP_668375.1 - 9.9 5.8 8.7 3 7.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TRM13 PF05206.14 XP_668376.1 - 6.2e-08 32.5 4.4 1.6e-07 31.1 0.2 2.2 2 0 0 2 2 2 2 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 XP_668376.1 - 3.2e-07 30.0 3.5 6.9e-07 28.9 3.5 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Med7 PF05983.11 XP_668377.1 - 2.1e-22 80.2 11.6 9.5e-21 74.8 11.6 2.0 1 1 0 1 1 1 1 MED7 protein BCDHK_Adom3 PF10436.9 XP_668377.1 - 0.0038 17.1 1.3 0.0048 16.8 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase EST1_DNA_bind PF10373.9 XP_668377.1 - 0.0081 15.7 0.3 0.0088 15.5 0.3 1.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DUF641 PF04859.12 XP_668377.1 - 0.019 15.3 1.5 0.025 14.9 1.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SKA2 PF16740.5 XP_668377.1 - 0.02 14.6 3.2 0.029 14.1 3.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 KASH_CCD PF14662.6 XP_668377.1 - 0.021 14.7 7.3 0.027 14.3 7.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1825 PF08855.10 XP_668377.1 - 0.027 14.4 2.8 0.043 13.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Sec2p PF06428.11 XP_668377.1 - 0.034 14.1 3.4 0.055 13.4 3.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SPACA9 PF15120.6 XP_668377.1 - 0.056 13.2 1.6 0.078 12.8 1.6 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 PCRF PF03462.18 XP_668377.1 - 0.26 11.1 2.6 0.32 10.8 2.6 1.1 1 0 0 1 1 1 0 PCRF domain Ufm1 PF03671.14 XP_668378.1 - 8.2e-16 57.9 0.1 1.1e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein PAR1 PF06521.11 XP_668379.1 - 0.091 12.4 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 PAR1 protein RNA_pol_Rpb2_6 PF00562.28 XP_668380.1 - 7.3e-120 400.6 0.0 1e-119 400.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 XP_668380.1 - 8.2e-34 116.9 0.0 1.6e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 XP_668380.1 - 2.3e-26 91.8 0.0 4.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 XP_668380.1 - 2.1e-19 69.7 0.0 4.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 XP_668380.1 - 7.2e-10 38.7 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 XP_668380.1 - 0.16 11.6 0.0 1.7 8.2 0.0 2.3 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 2 YchF-GTPase_C PF06071.13 XP_668381.1 - 2.3e-39 133.4 0.1 7.4e-39 131.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 XP_668381.1 - 7.1e-21 74.4 0.0 3.7e-20 72.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 XP_668381.1 - 8e-07 28.7 0.0 3.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 XP_668381.1 - 0.037 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 TGS domain AAA PF00004.29 XP_668381.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 XP_668382.1 - 1.8e-10 41.3 0.2 1.3e-09 38.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 XP_668382.1 - 0.0022 18.4 1.2 0.5 10.7 0.1 3.5 3 2 1 4 4 4 1 AAA ATPase domain DUF815 PF05673.13 XP_668382.1 - 0.0032 16.7 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 XP_668382.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 XP_668382.1 - 0.034 14.3 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2554 PF10829.8 XP_668382.1 - 0.034 14.5 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) ABC_tran PF00005.27 XP_668382.1 - 0.037 14.5 0.5 0.18 12.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 XP_668382.1 - 0.052 13.6 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 XP_668382.1 - 0.061 13.2 0.5 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 XP_668382.1 - 0.067 12.9 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 XP_668382.1 - 0.078 13.4 0.0 0.67 10.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 XP_668382.1 - 0.098 12.4 0.5 0.56 10.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 XP_668382.1 - 0.11 12.7 1.7 2.1 8.6 0.1 3.2 2 1 1 3 3 3 0 AAA domain DUF1493 PF07377.12 XP_668382.1 - 0.39 11.2 0.1 0.39 11.2 0.1 4.2 4 2 1 5 5 4 0 Protein of unknown function (DUF1493) Zw10 PF06248.13 XP_668383.1 - 2.8e-25 88.9 2.7 2.8e-25 88.9 2.7 1.6 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 RRM_1 PF00076.22 XP_668384.1 - 2.8e-49 164.8 0.0 1.2e-21 76.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 XP_668384.1 - 2.6e-05 24.3 0.0 0.069 13.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 XP_668384.1 - 0.0016 18.4 0.0 0.0083 16.1 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 XP_668384.1 - 0.038 13.6 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhlB PF12300.8 XP_668384.1 - 8.3 6.5 9.0 1.6 8.9 2.2 2.6 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB RNA_pol_A_bac PF01000.26 XP_668386.1 - 1.6e-26 92.8 0.0 3.1e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 XP_668386.1 - 7.8e-21 73.3 0.0 1.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M24 PF00557.24 XP_668387.1 - 1.2e-51 175.3 0.0 2.2e-51 174.5 0.0 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 XP_668387.1 - 1.1e-14 54.5 11.0 1.1e-14 54.5 11.0 2.0 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 XP_668387.1 - 5.2e-05 23.3 7.1 0.00014 21.9 7.1 1.8 1 0 0 1 1 1 1 MYND finger Clr5 PF14420.6 XP_668387.1 - 0.04 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Clr5 domain PolC_DP2 PF03833.13 XP_668387.1 - 0.49 8.2 5.4 0.54 8.0 1.4 2.0 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 XP_668387.1 - 2.1 8.7 7.0 10 6.5 7.0 2.3 1 1 0 1 1 1 0 C1 domain LSM PF01423.22 XP_668388.1 - 5.8e-18 64.3 0.1 8.3e-18 63.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain WBS_methylT PF12589.8 XP_668389.1 - 3e-21 75.9 1.8 4.1e-21 75.5 1.8 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Ank_2 PF12796.7 XP_668390.1 - 4.3e-23 81.7 3.0 8.1e-07 29.5 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 XP_668390.1 - 7.3e-17 61.5 0.7 6.8e-06 26.5 0.1 5.1 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_668390.1 - 2e-12 46.1 0.6 0.014 15.9 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 XP_668390.1 - 1.1e-10 41.5 0.1 0.036 14.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 XP_668390.1 - 3.4e-06 27.2 0.6 0.09 13.1 0.0 5.0 2 2 4 6 6 6 2 Ankyrin repeats (many copies) TPR_1 PF00515.28 XP_668390.1 - 4.6e-05 23.1 0.0 0.016 15.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668390.1 - 0.00012 21.9 0.0 0.46 10.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668390.1 - 0.014 15.6 1.0 5 7.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 XP_668390.1 - 0.039 13.6 0.1 0.22 11.2 0.0 2.3 3 0 0 3 3 3 0 TPR repeat Acetyltransf_1 PF00583.25 XP_668392.1 - 1.7e-15 57.2 0.0 2.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 XP_668392.1 - 9e-11 41.8 0.0 9.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 XP_668392.1 - 1.3e-09 38.4 0.0 1.7e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 XP_668392.1 - 3.1e-06 27.4 0.1 3.6e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 XP_668392.1 - 8e-05 22.5 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 XP_668392.1 - 0.0078 16.3 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 XP_668392.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase HA2 PF04408.23 XP_668393.1 - 6.5e-23 81.1 0.1 2.3e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 XP_668393.1 - 3.7e-18 65.7 0.0 9.1e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 XP_668393.1 - 1.2e-12 48.1 0.0 6.4e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 XP_668393.1 - 6.3e-05 23.3 0.2 0.00033 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 XP_668393.1 - 0.00081 19.2 0.0 0.003 17.4 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 XP_668393.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 XP_668393.1 - 0.0017 18.7 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 XP_668393.1 - 0.0032 17.2 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Glug PF07581.12 XP_668393.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 The GLUG motif Flavi_DEAD PF07652.14 XP_668393.1 - 0.17 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 XP_668393.1 - 0.41 11.1 0.1 0.41 11.1 0.1 4.0 2 1 1 3 3 2 0 AAA domain DUF3585 PF12130.8 XP_668393.1 - 3.3 7.9 10.6 0.36 11.0 4.8 2.3 3 0 0 3 3 3 0 Bivalent Mical/EHBP Rab binding domain zf-ANAPC11 PF12861.7 XP_668394.1 - 2.3e-27 94.9 7.2 2.8e-27 94.6 7.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 XP_668394.1 - 1.7e-20 73.1 11.7 2.2e-20 72.7 11.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 XP_668394.1 - 2.9e-08 33.9 15.7 5.8e-07 29.7 15.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 XP_668394.1 - 1.3e-05 25.1 12.0 2.4e-05 24.2 10.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 XP_668394.1 - 5e-05 23.2 11.5 0.0007 19.5 11.6 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 XP_668394.1 - 0.00017 21.4 15.7 0.0013 18.6 15.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 XP_668394.1 - 0.00045 20.3 3.3 0.00045 20.3 3.3 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 XP_668394.1 - 0.00091 19.0 11.7 0.013 15.3 8.4 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 XP_668394.1 - 0.0031 17.3 13.8 0.018 14.9 8.2 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 XP_668394.1 - 0.0033 17.3 8.1 0.0033 17.3 8.1 2.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 XP_668394.1 - 0.011 15.5 5.0 0.017 14.9 5.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.16 XP_668394.1 - 0.015 15.2 4.8 0.018 14.9 1.5 2.3 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 XP_668394.1 - 0.018 14.9 0.6 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 XP_668394.1 - 0.083 12.7 17.9 0.15 11.8 14.3 2.7 2 1 0 2 2 2 0 RING-like zinc finger Pellino PF04710.14 XP_668394.1 - 0.11 11.2 3.8 0.06 12.0 2.0 1.4 1 1 0 1 1 1 0 Pellino Zn-C2H2_12 PF18112.1 XP_668394.1 - 0.2 12.2 0.3 0.2 12.2 0.3 3.2 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-HC5HC2H_2 PF13832.6 XP_668394.1 - 0.46 10.7 7.3 0.13 12.4 3.9 1.7 1 1 1 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.8 XP_668394.1 - 0.58 10.4 14.9 5.3 7.3 14.6 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain TerY_C PF15616.6 XP_668394.1 - 0.99 9.5 7.1 0.16 12.0 3.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain RecR PF02132.15 XP_668394.1 - 2.2 7.9 7.4 3.5 7.3 1.1 3.0 3 0 0 3 3 3 0 RecR protein Zn_ribbon_17 PF17120.5 XP_668394.1 - 4.4 7.0 13.8 29 4.4 13.8 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 XP_668394.1 - 8.1 6.5 16.2 9.4 6.2 0.0 3.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 XP_668394.1 - 8.2 7.1 16.0 1.9 9.1 0.3 4.1 3 1 0 3 3 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 XP_668395.1 - 6.3e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668395.1 - 2.1e-08 33.8 0.0 5.4e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase TypeIII_RM_meth PF12564.8 XP_668395.1 - 0.15 12.2 0.4 0.15 12.2 0.4 1.8 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Na_Ca_ex PF01699.24 XP_668396.1 - 2.7e-38 131.3 41.4 4.4e-22 78.7 17.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2627 PF11118.8 XP_668396.1 - 0.08 13.5 2.3 0.6 10.7 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) ThiF PF00899.21 XP_668399.1 - 2.1e-54 184.5 0.0 2.6e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 XP_668399.1 - 0.0063 16.6 0.5 0.014 15.4 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 XP_668399.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 XP_668399.1 - 0.044 14.4 0.2 0.21 12.2 0.2 2.1 2 0 0 2 2 2 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 XP_668399.1 - 0.055 13.0 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.21 XP_668399.1 - 0.07 12.8 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 XP_668399.1 - 0.077 12.3 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PLDc_2 PF13091.6 XP_668400.1 - 1e-08 35.2 0.5 0.0034 17.3 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 XP_668400.1 - 0.004 17.3 2.0 0.012 15.8 0.1 2.5 2 0 0 2 2 2 1 Phospholipase D Active site motif MCM PF00493.23 XP_668401.1 - 1.1e-99 332.0 0.1 1.9e-99 331.3 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 XP_668401.1 - 4.3e-36 123.5 0.1 9.1e-36 122.5 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 XP_668401.1 - 5e-25 87.7 0.2 1.5e-24 86.2 0.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 XP_668401.1 - 7.6e-18 65.3 16.6 7.6e-18 65.3 16.6 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 XP_668401.1 - 7.6e-14 52.2 0.5 7.6e-14 52.2 0.5 3.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 XP_668401.1 - 5.5e-07 29.2 0.0 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 XP_668401.1 - 0.00017 21.4 0.0 0.00051 19.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 XP_668401.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 XP_668401.1 - 0.0055 16.4 0.0 0.063 13.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain MBOAT PF03062.19 XP_668402.1 - 2.7e-20 73.0 33.1 8.5e-20 71.4 33.1 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 XP_668402.1 - 3.2 8.1 10.5 0.25 11.7 4.5 2.4 3 0 0 3 3 3 0 Membrane bound O-acyl transferase family Phage_FRD3 PF05798.11 XP_668403.1 - 0.14 12.4 4.6 4 7.8 0.2 3.7 2 1 0 3 3 3 0 Bacteriophage FRD3 protein Ribosomal_S25 PF03297.15 XP_668404.1 - 1.1e-35 121.8 3.1 1.3e-35 121.6 3.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Pkinase PF00069.25 XP_668405.1 - 2.8e-78 263.0 0.0 4.1e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668405.1 - 1.8e-35 122.5 0.0 3.7e-35 121.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 XP_668405.1 - 9.1e-27 90.6 6.1 3.7e-08 32.3 2.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_668405.1 - 2.3e-23 82.4 0.2 2.6e-11 43.8 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_668405.1 - 9.6e-22 75.0 3.3 7.9e-06 25.4 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 XP_668405.1 - 5e-17 60.5 6.6 0.00061 19.2 1.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 XP_668405.1 - 1.3e-14 53.7 7.8 0.00072 19.4 0.7 5.2 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 XP_668405.1 - 1.4e-05 24.9 0.5 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Pkinase_fungal PF17667.1 XP_668405.1 - 1.7e-05 23.8 0.0 2.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 XP_668405.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EF-hand_9 PF14658.6 XP_668405.1 - 0.0016 18.7 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Kdo PF06293.14 XP_668405.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 XP_668405.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 XP_668405.1 - 0.061 13.6 0.1 22 5.4 0.1 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 XP_668405.1 - 0.2 11.9 3.6 0.83 9.9 1.4 3.1 3 1 1 4 4 3 0 Dockerin type I domain Brr6_like_C_C PF10104.9 XP_668406.1 - 9.9 5.9 8.4 1.9 8.3 0.6 2.6 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Cyt-b5 PF00173.28 XP_668407.1 - 1.1e-13 51.1 0.1 2.1e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 XP_668408.1 - 1.1e-60 201.6 1.9 9.8e-20 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 XP_668409.1 - 6.8e-08 33.0 0.1 6.8e-08 33.0 0.1 2.6 3 0 0 3 3 3 1 PCI domain CUB_2 PF02408.20 XP_668410.1 - 0.0085 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 CUB-like domain ADAM_spacer1 PF05986.14 XP_668410.1 - 0.097 12.7 0.2 0.14 12.3 0.2 1.3 1 1 0 1 1 1 0 ADAM-TS Spacer 1 DEAD PF00270.29 XP_668411.1 - 1.2e-48 165.2 0.0 3.1e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668411.1 - 1.9e-30 105.5 0.0 1e-29 103.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668411.1 - 0.00068 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 XP_668411.1 - 0.0031 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ArfGap PF01412.18 XP_668411.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CMS1 PF14617.6 XP_668411.1 - 0.073 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.22 XP_668412.1 - 2.2e-13 49.8 0.0 8e-11 41.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1897 PF09005.10 XP_668412.1 - 0.21 11.1 0.5 0.39 10.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) TGT PF01702.18 XP_668413.1 - 1.1e-29 103.7 0.0 1.9e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RNA_pol_Rpb5_C PF01191.19 XP_668414.1 - 2.4e-34 117.0 0.3 4.4e-34 116.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 XP_668414.1 - 5.4e-22 78.2 2.2 8.5e-22 77.5 2.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 XP_668414.1 - 0.0064 16.5 0.3 0.015 15.3 0.3 1.8 1 1 0 1 1 1 1 Restriction endonuclease Tcp10_C PF07202.13 XP_668416.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 2.7 2 1 1 3 3 3 1 T-complex protein 10 C-terminus ERM PF00769.19 XP_668416.1 - 0.0018 18.2 24.4 0.0018 18.2 24.4 1.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 XP_668416.1 - 1.2 8.7 12.9 2 7.9 12.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PPTA PF01239.22 XP_668417.1 - 0.14 11.9 5.7 12 5.8 0.2 4.6 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat Spore_III_AB PF09548.10 XP_668417.1 - 3.2 7.8 9.5 11 6.1 2.3 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_M16_M PF16187.5 XP_668419.1 - 7.9e-34 117.2 7.9 5.3e-33 114.5 3.4 2.6 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 XP_668419.1 - 1.7e-33 115.7 0.0 3.3e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 XP_668419.1 - 6e-26 91.6 1.4 3.6e-17 63.0 0.1 3.5 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_668420.1 - 1.1e-33 116.3 2.1 1.8e-33 115.6 0.3 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 XP_668420.1 - 6.7e-25 87.9 8.5 6.7e-25 87.9 8.5 2.5 2 1 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 XP_668420.1 - 7.8e-17 61.9 0.1 1.4e-14 54.5 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Pkinase PF00069.25 XP_668421.1 - 1.5e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 XP_668421.1 - 0.034 12.9 0.4 0.057 12.2 0.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase Cpn60_TCP1 PF00118.24 XP_668422.1 - 9.6e-144 479.6 4.7 1.1e-143 479.5 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LSM14 PF12701.7 XP_668423.1 - 0.042 14.0 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Scd6-like Sm domain EIID-AGA PF03613.14 XP_668423.1 - 0.083 12.1 0.7 0.2 10.8 0.7 1.5 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component SNF2_N PF00176.23 XP_668424.1 - 1.3e-52 178.7 1.6 2.3e-52 177.9 1.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_668424.1 - 8.6e-17 61.5 3.4 3.9e-15 56.1 0.1 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668424.1 - 8.8e-12 45.4 0.3 8.8e-12 45.4 0.3 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_668424.1 - 7.4e-08 32.4 0.0 2.4e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve_2 PF13333.6 XP_668424.1 - 0.11 12.7 2.8 3.9 7.7 0.0 3.3 3 0 0 3 3 3 0 Integrase core domain RACo_linker PF17650.1 XP_668425.1 - 0.12 12.2 0.6 11 6.0 0.1 2.2 2 0 0 2 2 2 0 RACo linker region partial_CstF PF15861.5 XP_668427.1 - 6.4e-16 57.9 1.6 1.7e-15 56.5 0.7 2.0 1 1 1 2 2 2 1 Partial cleavage stimulation factor domain CSTF2_hinge PF14327.6 XP_668427.1 - 2.8e-13 50.1 0.3 8.5e-13 48.6 0.3 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 XP_668427.1 - 4.9e-10 39.1 0.0 9.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 XP_668428.1 - 1.1e-20 72.6 5.7 1.7e-05 24.4 0.0 6.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668428.1 - 4.5e-19 67.0 0.1 1.4e-05 24.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668428.1 - 1.9e-18 65.0 4.7 5.9e-05 23.0 0.0 6.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 XP_668428.1 - 4.7e-16 57.9 3.9 0.00037 20.7 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 XP_668428.1 - 5.9e-10 38.7 0.4 0.017 14.8 0.0 5.3 2 1 4 6 6 6 4 TPR repeat TPR_7 PF13176.6 XP_668428.1 - 2.5e-09 36.5 0.0 0.087 12.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 XP_668428.1 - 4.2e-09 36.6 0.0 0.0092 16.3 0.0 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 XP_668428.1 - 2.9e-07 30.1 0.0 1.1 9.2 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 XP_668428.1 - 1.5e-06 28.6 0.0 1 9.9 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 XP_668428.1 - 0.00046 20.8 0.0 15 6.7 0.0 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 XP_668428.1 - 0.0034 17.9 0.0 33 5.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 XP_668428.1 - 0.03 14.5 0.0 8.6 6.6 0.0 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 XP_668428.1 - 0.046 13.2 3.9 2.1 7.7 0.4 2.8 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain NARP1 PF12569.8 XP_668428.1 - 0.094 11.6 0.0 1.9 7.3 0.0 2.6 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 KH_1 PF00013.29 XP_668430.1 - 3.9e-26 90.7 0.8 6e-07 29.2 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 XP_668430.1 - 1.1e-05 25.2 0.3 0.042 13.7 0.0 4.2 4 1 0 4 4 4 1 KH domain KH_2 PF07650.17 XP_668430.1 - 2.8e-05 23.8 1.1 2.2 8.1 0.0 4.1 3 1 1 4 4 4 2 KH domain DUF2969 PF11184.8 XP_668430.1 - 0.0034 17.8 0.4 1.9 8.9 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2969) CHZ PF09649.10 XP_668430.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ Peptidase_C97 PF05903.14 XP_668431.1 - 9.7e-42 142.3 0.0 1.5e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 XP_668431.1 - 2e-13 50.0 0.2 6.3e-13 48.5 0.1 1.8 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 XP_668431.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 XP_668431.1 - 0.01 15.9 0.3 0.019 15.0 0.3 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair DUF5610 PF18433.1 XP_668431.1 - 0.078 13.5 0.1 0.96 10.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) SCP_3 PF17844.1 XP_668431.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog Period_C PF12114.8 XP_668431.1 - 0.37 10.3 9.7 2.7 7.5 6.0 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Presenilin PF01080.17 XP_668432.1 - 0.065 12.0 10.6 0.08 11.7 10.6 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 XP_668432.1 - 0.17 10.5 6.6 0.19 10.4 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RPN2_C PF18004.1 XP_668432.1 - 0.18 11.7 17.2 0.33 10.9 17.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SOBP PF15279.6 XP_668432.1 - 0.27 11.8 10.0 0.33 11.5 10.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 XP_668432.1 - 0.28 9.8 12.5 0.35 9.5 12.5 1.1 1 0 0 1 1 1 0 Hamartin protein Pacs-1 PF10254.9 XP_668432.1 - 0.3 10.0 9.6 0.41 9.6 9.6 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Neur_chan_memb PF02932.16 XP_668432.1 - 0.37 10.8 7.9 0.56 10.2 7.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 XP_668432.1 - 0.46 10.3 18.0 0.65 9.8 18.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 XP_668432.1 - 0.51 8.6 20.2 0.69 8.1 20.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Smg8_Smg9 PF10220.9 XP_668432.1 - 1.2 7.3 13.5 1.6 6.9 13.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF5427 PF10310.9 XP_668432.1 - 1.8 7.4 18.5 2.6 6.9 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SpoIIIAH PF12685.7 XP_668432.1 - 2.6 7.8 17.3 4.2 7.2 17.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Dsh_C PF12316.8 XP_668432.1 - 6.5 7.1 10.9 9.9 6.5 10.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CAP_N PF01213.19 XP_668433.1 - 1.8 8.0 7.4 3.4 7.1 7.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CRAL_TRIO PF00650.20 XP_668434.1 - 2.7e-31 108.5 0.0 4.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 XP_668434.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_C97 PF05903.14 XP_668434.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 PPPDE putative peptidase domain Ribonuc_2-5A PF06479.12 XP_668435.1 - 0.013 15.7 2.2 0.33 11.2 0.3 3.1 3 0 0 3 3 3 0 Ribonuclease 2-5A BAF PF02961.14 XP_668435.1 - 0.08 13.4 0.0 0.31 11.5 0.0 2.0 1 0 0 1 1 1 0 Barrier to autointegration factor Pkinase PF00069.25 XP_668436.1 - 5.6e-55 186.5 0.3 1.2e-49 169.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668436.1 - 7.9e-22 77.8 0.2 1.5e-15 57.2 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 XP_668436.1 - 0.004 17.1 2.5 0.013 15.4 0.9 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 XP_668436.1 - 0.017 13.9 6.8 0.018 13.8 0.1 2.4 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 XP_668436.1 - 0.029 13.7 0.1 0.14 11.4 0.1 2.1 1 1 0 1 1 1 0 Kinase-like DUF2193 PF09959.9 XP_668438.1 - 0.047 12.1 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) SNF2_N PF00176.23 XP_668439.1 - 2.9e-55 187.4 0.0 4.8e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 XP_668439.1 - 5.4e-14 52.5 0.0 1.5e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668439.1 - 7.8e-12 45.5 0.0 1.9e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 XP_668439.1 - 6.4e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 XP_668439.1 - 0.0018 18.0 0.1 0.004 16.9 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 XP_668439.1 - 0.0074 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Peptidase_C12 PF01088.21 XP_668440.1 - 2e-54 184.5 0.0 3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 XP_668440.1 - 9.8e-15 54.2 0.6 2.5e-14 52.9 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Bacillus_HBL PF05791.11 XP_668440.1 - 0.033 14.0 0.4 0.064 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Ank_2 PF12796.7 XP_668443.1 - 5.1e-20 71.9 0.3 1.8e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ACBP PF00887.19 XP_668443.1 - 1.3e-18 66.9 0.7 2.6e-18 66.0 0.7 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 XP_668443.1 - 1.9e-17 63.1 0.0 2.2e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 XP_668443.1 - 6e-12 45.4 0.1 1.2e-05 25.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 XP_668443.1 - 6.9e-11 42.5 0.1 8.8e-08 32.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 XP_668443.1 - 4.5e-09 35.8 0.1 0.00076 19.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SF-assemblin PF06705.11 XP_668444.1 - 7.4e-11 41.9 3.5 7.4e-11 41.9 3.5 2.7 1 1 2 3 3 3 1 SF-assemblin/beta giardin GSIII_N PF12437.8 XP_668444.1 - 0.0076 15.9 0.7 0.026 14.2 0.1 2.1 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal DUF948 PF06103.11 XP_668444.1 - 0.072 13.3 3.6 18 5.7 0.1 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 XP_668444.1 - 0.077 13.5 6.1 1 9.9 0.0 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM25 PF15825.5 XP_668444.1 - 0.085 13.2 0.4 9 6.7 0.1 2.5 2 0 0 2 2 2 0 FAM25 family Ribosomal_L35Ae PF01247.18 XP_668444.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L35Ae APG17 PF04108.12 XP_668444.1 - 0.12 11.5 13.6 0.031 13.4 0.8 3.0 1 1 1 3 3 3 0 Autophagy protein Apg17 DUF1664 PF07889.12 XP_668444.1 - 0.15 12.1 12.8 0.47 10.5 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2400 PF09674.10 XP_668444.1 - 0.21 11.5 10.2 0.18 11.8 3.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) DUF3037 PF11236.8 XP_668444.1 - 0.26 11.7 2.4 1.4 9.4 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3037) Tup_N PF08581.10 XP_668444.1 - 0.42 11.0 9.0 0.82 10.0 0.3 3.4 2 1 1 3 3 3 0 Tup N-terminal Tiam_CC_Ex PF18385.1 XP_668444.1 - 0.43 11.0 3.9 3.1 8.2 0.2 2.6 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain FAS_I_H PF18314.1 XP_668444.1 - 0.57 9.8 7.0 5.5 6.6 0.3 3.3 1 1 2 4 4 4 0 Fatty acid synthase type I helical domain KELK PF15796.5 XP_668444.1 - 0.58 10.7 9.4 3 8.4 0.4 3.5 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2383 PF09537.10 XP_668444.1 - 0.88 9.9 5.1 0.93 9.9 0.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Chalcone_2 PF16035.5 XP_668444.1 - 1.3 8.8 6.1 13 5.5 0.1 3.0 2 1 1 3 3 3 0 Chalcone isomerase like PRANC PF09372.10 XP_668444.1 - 1.3 9.4 9.4 0.27 11.6 1.0 3.1 1 1 2 3 3 3 0 PRANC domain TolA_bind_tri PF16331.5 XP_668444.1 - 1.7 8.8 7.4 2.8 8.1 2.0 3.1 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF16 PF01519.16 XP_668444.1 - 1.9 9.1 18.5 0.11 13.0 4.7 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 GCN5L1 PF06320.13 XP_668444.1 - 2.2 8.5 11.6 6.9 6.8 2.4 3.3 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) ENTH PF01417.20 XP_668445.1 - 6.3e-11 42.4 3.9 8.6e-09 35.5 0.0 2.7 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 XP_668445.1 - 0.0047 16.0 0.2 0.21 10.5 0.0 2.3 2 0 0 2 2 2 2 ANTH domain Colicin_Pyocin PF01320.18 XP_668445.1 - 0.12 12.5 1.6 0.73 10.0 0.0 3.1 4 0 0 4 4 4 0 Colicin immunity protein / pyocin immunity protein PSS PF03034.15 XP_668446.1 - 1.5e-83 280.7 13.3 1.5e-83 280.7 13.3 1.8 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF4079 PF13301.6 XP_668446.1 - 0.027 14.6 0.1 0.027 14.6 0.1 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF4079) Peptidase_S15 PF02129.18 XP_668447.1 - 1.3e-30 106.9 0.2 9.4e-26 91.0 0.3 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 XP_668447.1 - 1.7e-11 44.5 0.0 4.8e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 XP_668447.1 - 0.00019 20.8 0.1 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 V_ATPase_I PF01496.19 XP_668448.1 - 1.7 6.5 9.1 2 6.2 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CdiA_C PF18451.1 XP_668448.1 - 2.8 8.2 9.3 0.13 12.5 1.2 2.4 2 1 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Presenilin PF01080.17 XP_668448.1 - 4 6.1 7.1 4.4 6.0 7.1 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 XP_668448.1 - 8.6 5.1 10.7 9.8 4.9 10.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-B_box PF00643.24 XP_668449.1 - 1.4e-06 28.3 9.6 1.4e-06 28.3 9.6 3.0 4 0 0 4 4 4 2 B-box zinc finger Methyltransf_25 PF13649.6 XP_668449.1 - 0.019 15.7 0.1 1.1 10.1 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain zf-ANAPC11 PF12861.7 XP_668449.1 - 0.043 13.9 0.7 0.043 13.9 0.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3645 PF12359.8 XP_668449.1 - 0.24 10.8 0.5 7.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) zf-C3HC4_3 PF13920.6 XP_668449.1 - 0.84 9.5 37.2 0.14 12.0 8.6 4.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 XP_668450.1 - 9.5e-14 51.0 3.7 6.3e-10 38.7 0.5 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Topoisom_bac PF01131.20 XP_668451.1 - 4e-13 49.2 0.1 1.5e-11 44.0 0.1 2.1 1 1 1 2 2 2 2 DNA topoisomerase DUF2024 PF09630.10 XP_668451.1 - 0.25 11.3 3.2 5.4 7.0 0.6 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2024) Topoisom_bac PF01131.20 XP_668452.1 - 1.4e-61 208.8 0.0 1.9e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 XP_668452.1 - 2.7e-12 46.8 0.0 7.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Transpos_assoc PF13963.6 XP_668452.1 - 0.024 15.0 0.6 0.13 12.6 0.1 2.5 2 1 1 3 3 3 0 Transposase-associated domain Lactamase_B_6 PF16661.5 XP_668453.1 - 7.2e-21 74.5 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 XP_668453.1 - 3.7e-20 72.3 0.0 8.2e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 XP_668453.1 - 2.7e-13 49.6 0.3 8.4e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 XP_668453.1 - 3.1e-11 43.6 0.0 1e-07 32.2 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 XP_668453.1 - 2.4e-06 27.2 0.0 2e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 XP_668453.1 - 0.0015 18.4 0.0 0.0078 16.1 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BTB PF00651.31 XP_668454.1 - 3.5e-13 49.7 0.0 6.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CENP-F_C_Rb_bdg PF10490.9 XP_668454.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Whirly PF08536.11 XP_668454.1 - 0.022 14.6 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Whirly transcription factor Med26 PF08711.11 XP_668455.1 - 4.9e-05 23.3 2.0 4.9e-05 23.3 2.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RsbRD_N PF14361.6 XP_668455.1 - 0.016 15.9 0.2 0.93 10.2 0.0 2.7 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Epimerase PF01370.21 XP_668456.1 - 3.5e-28 98.7 0.0 8.3e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 XP_668456.1 - 1e-20 73.9 0.2 1.7e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 XP_668456.1 - 3.8e-20 72.2 0.0 3.8e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 XP_668456.1 - 1.1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 XP_668456.1 - 8.1e-14 51.9 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 XP_668456.1 - 1.8e-09 37.5 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 XP_668456.1 - 2.6e-07 30.1 0.0 4.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 XP_668456.1 - 3.5e-05 23.8 0.0 8.4e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 XP_668456.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 XP_668456.1 - 0.0024 17.4 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 XP_668456.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 XP_668457.1 - 1.1e-25 89.4 19.1 9.3e-05 23.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 XP_668457.1 - 3.3e-13 48.9 1.0 5.3e-13 48.3 1.0 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 XP_668457.1 - 4.2e-06 27.0 1.4 0.11 12.9 0.0 4.7 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 XP_668457.1 - 0.00035 19.4 5.2 0.1 11.2 0.1 4.3 3 2 2 5 5 5 2 Nucleoporin Nup120/160 SANT_DAMP1_like PF16282.5 XP_668458.1 - 4.2e-27 94.1 2.4 4.2e-27 94.1 2.4 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 STATa_Ig PF18214.1 XP_668458.1 - 0.064 13.3 0.1 0.3 11.1 0.1 2.2 1 1 0 1 1 1 0 STATa Immunoglobulin-like domain SSXT PF05030.12 XP_668459.1 - 2.1e-05 24.0 0.3 5.4e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-C2H2 PF00096.26 XP_668459.1 - 0.0047 17.3 3.8 0.014 15.8 3.8 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 XP_668459.1 - 0.016 14.8 0.7 0.037 13.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF1189 PF06691.11 XP_668459.1 - 0.049 13.2 1.5 0.051 13.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Cas_CXXC_CXXC PF09706.10 XP_668459.1 - 0.054 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-C2H2_4 PF13894.6 XP_668459.1 - 0.065 14.1 2.9 0.28 12.1 2.9 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger PyrI_C PF02748.15 XP_668459.1 - 0.14 12.1 6.1 2.4 8.1 0.5 3.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Baculo_PEP_C PF04513.12 XP_668460.1 - 0.044 13.8 3.0 0.1 12.6 3.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 XP_668460.1 - 0.067 13.2 1.3 0.19 11.8 1.3 1.8 1 0 0 1 1 1 0 Laminin Domain II Acyltransferase PF01553.21 XP_668462.1 - 1.4e-12 47.4 0.0 3.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF999 PF06198.11 XP_668462.1 - 0.18 11.8 3.9 0.51 10.3 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Torus PF16131.5 XP_668463.1 - 5.1e-08 33.6 15.9 2.8e-05 24.7 0.8 3.7 2 1 2 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 XP_668463.1 - 5.5e-07 29.8 7.9 1.2e-06 28.7 7.9 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 XP_668463.1 - 1.6e-06 27.7 25.5 2.1e-06 27.4 1.9 4.8 5 1 0 5 5 5 2 CCCH-type zinc finger zf-CCCH PF00642.24 XP_668463.1 - 2.4e-06 27.3 16.9 3.4e-05 23.6 1.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 XP_668463.1 - 1e-05 25.4 26.7 2.3e-05 24.3 5.8 4.6 3 2 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 XP_668463.1 - 0.0025 18.2 19.6 0.17 12.4 0.6 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 XP_668463.1 - 0.064 13.0 9.2 1.9 8.3 0.4 3.4 3 0 0 3 3 3 0 Putative zinc-finger domain CLIP PF12032.8 XP_668463.1 - 0.1 12.9 3.0 0.42 10.9 0.2 2.8 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases VPR PF00522.18 XP_668464.1 - 0.039 14.0 2.4 3.3 7.8 0.1 2.6 2 1 0 2 2 2 0 VPR/VPX protein Mvb12 PF09452.10 XP_668464.1 - 0.47 10.9 6.6 2.8 8.4 0.1 2.8 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF4404 PF14357.6 XP_668464.1 - 2.2 9.0 14.8 5.3 7.7 2.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) CLZ PF16526.5 XP_668464.1 - 2.3 8.6 12.6 0.087 13.2 1.9 3.2 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 XP_668465.1 - 0.00013 21.6 0.4 0.00023 20.8 0.4 1.5 1 0 0 1 1 1 1 Allexivirus 40kDa protein ApoLp-III PF07464.11 XP_668465.1 - 0.041 14.0 3.4 0.15 12.1 3.7 1.8 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 XP_668465.1 - 0.069 13.2 6.0 0.039 14.0 2.4 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 XP_668465.1 - 0.07 13.2 3.4 1.7 8.7 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 XP_668465.1 - 0.24 12.0 2.0 0.62 10.6 1.4 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal MIP-T3_C PF17749.1 XP_668465.1 - 1.8 8.5 8.0 2.3 8.2 6.0 2.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region ArfGap PF01412.18 XP_668466.1 - 1.1e-30 106.1 0.1 1.7e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Herpes_UL52 PF03121.15 XP_668466.1 - 0.34 10.9 2.9 10 6.1 0.2 2.4 1 1 1 2 2 2 0 Herpesviridae UL52/UL70 DNA primase zf-RanBP PF00641.18 XP_668466.1 - 6 6.3 6.1 0.54 9.6 0.7 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Cas_Cas6 PF01881.16 XP_668468.1 - 0.0057 17.2 4.5 0.044 14.3 1.0 2.5 1 1 1 2 2 2 2 CRISPR associated protein Cas6 DUF1841 PF08897.11 XP_668468.1 - 0.0075 16.3 0.5 0.017 15.1 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1841) Mg_trans_NIPA PF05653.14 XP_668469.1 - 3.3e-21 75.7 21.6 3.7e-14 52.5 6.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SieB PF14163.6 XP_668469.1 - 6.1e-06 25.8 0.2 0.011 15.2 0.0 2.9 2 0 0 2 2 2 2 Super-infection exclusion protein B DUF2371 PF10177.9 XP_668469.1 - 6.9 6.8 5.7 27 4.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) EamA PF00892.20 XP_668469.1 - 8.9 6.5 27.6 0.063 13.5 6.7 3.9 3 1 1 4 4 4 0 EamA-like transporter family B-block_TFIIIC PF04182.12 XP_668471.1 - 5.4e-14 52.1 1.9 4.6e-09 36.3 0.0 3.7 2 1 0 2 2 2 2 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.17 XP_668471.1 - 0.0079 16.0 1.5 0.094 12.6 0.2 3.3 3 0 0 3 3 3 1 TFIIE alpha subunit ACI44 PF15270.6 XP_668471.1 - 0.028 14.6 0.1 0.13 12.4 0.1 2.2 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor zf-C2H2_4 PF13894.6 XP_668471.1 - 1.2 10.1 3.6 4.6 8.3 3.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L13 PF00572.18 XP_668473.1 - 1.8e-07 31.4 0.1 4.7e-05 23.6 0.0 2.8 1 1 1 2 2 2 1 Ribosomal protein L13 TLD PF07534.16 XP_668474.1 - 8.5e-30 103.8 3.7 2.1e-14 53.9 0.2 2.1 1 1 0 2 2 2 2 TLD PCI PF01399.27 XP_668475.1 - 1.3e-09 38.5 0.3 4.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain Histone PF00125.24 XP_668476.1 - 3e-15 56.7 0.0 3.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 XP_668476.1 - 2.7e-10 39.8 1.1 7.6e-10 38.4 1.1 1.8 1 1 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 XP_668476.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRP1_N PF06424.12 XP_668478.1 - 1.8e-34 119.3 7.7 2.5e-34 118.8 4.9 2.6 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 XP_668478.1 - 1.8e-16 59.4 0.0 1.3 10.1 0.0 9.4 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 XP_668478.1 - 1.2e-09 38.6 0.0 2.6 8.6 0.2 7.7 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 XP_668478.1 - 1.6e-07 30.8 0.4 0.015 14.5 0.2 5.1 3 1 2 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 XP_668478.1 - 1.5e-05 25.2 3.3 0.00017 21.7 0.3 3.4 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 XP_668478.1 - 5.1e-05 23.1 3.8 0.32 11.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 XP_668478.1 - 0.00047 20.3 5.2 22 5.7 0.0 8.2 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668478.1 - 0.0075 16.0 0.9 4 7.4 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668478.1 - 0.0087 16.2 0.0 0.83 10.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 XP_668478.1 - 0.15 12.4 0.8 4.9 7.5 0.0 3.9 6 1 0 6 6 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 XP_668478.1 - 0.19 11.7 1.7 5 7.1 0.1 3.8 3 1 1 4 4 4 0 Mad3/BUB1 homology region 1 ParA PF10609.9 XP_668480.1 - 1.9e-47 161.8 0.0 3e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 XP_668480.1 - 1e-10 42.1 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) UBA_3 PF09288.10 XP_668481.1 - 0.052 13.4 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain SmAKAP PF15127.6 XP_668481.1 - 0.14 13.4 0.0 0.35 12.1 0.0 1.7 1 0 0 1 1 1 0 Small membrane A-kinase anchor protein WD40 PF00400.32 XP_668482.1 - 0.00042 21.0 0.0 0.16 12.9 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat TIP49 PF06068.13 XP_668483.1 - 1.5e-158 527.6 0.1 1.8e-158 527.3 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 XP_668483.1 - 6.2e-21 74.3 0.1 2.3e-20 72.5 0.1 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 XP_668483.1 - 1.3e-12 48.3 0.0 4e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 XP_668483.1 - 3.5e-09 36.6 0.1 1.6e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 XP_668483.1 - 1.4e-08 35.1 0.0 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 XP_668483.1 - 7.8e-06 25.9 0.0 0.00078 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 XP_668483.1 - 2.3e-05 24.8 0.2 0.044 14.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 XP_668483.1 - 4.3e-05 24.0 0.0 0.00025 21.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 XP_668483.1 - 0.00015 21.6 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 XP_668483.1 - 0.00017 21.0 0.1 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 XP_668483.1 - 0.001 19.1 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 XP_668483.1 - 0.0013 18.2 0.1 0.0054 16.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 XP_668483.1 - 0.0016 18.7 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 XP_668483.1 - 0.0017 18.0 0.2 0.004 16.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 XP_668483.1 - 0.0019 18.8 0.0 0.0046 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 XP_668483.1 - 0.0029 16.7 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 XP_668483.1 - 0.0047 16.2 0.1 0.0086 15.4 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.17 XP_668483.1 - 0.006 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 XP_668483.1 - 0.0067 16.5 0.0 0.13 12.4 0.0 2.7 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 XP_668483.1 - 0.0071 16.4 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 XP_668483.1 - 0.014 15.8 0.1 0.037 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 XP_668483.1 - 0.017 14.8 0.1 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 XP_668483.1 - 0.027 13.8 0.1 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 XP_668483.1 - 0.03 14.9 0.0 0.22 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 XP_668483.1 - 0.033 14.4 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 XP_668483.1 - 0.036 14.0 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_C PF03796.15 XP_668483.1 - 0.041 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 XP_668483.1 - 0.042 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_2 PF07724.14 XP_668483.1 - 0.045 13.9 0.2 0.41 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 XP_668483.1 - 0.046 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 XP_668483.1 - 0.055 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 XP_668483.1 - 0.07 13.0 0.1 0.29 11.0 0.0 2.1 2 1 0 2 2 1 0 NTPase DUF2075 PF09848.9 XP_668483.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 XP_668483.1 - 0.089 12.2 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 XP_668483.1 - 0.093 11.9 0.0 9.8 5.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.15 XP_668483.1 - 0.096 12.7 0.1 2 8.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 XP_668483.1 - 0.12 12.1 0.1 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Peptidase_M16_C PF05193.21 XP_668484.1 - 5.5e-24 85.2 0.1 2.4e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 XP_668484.1 - 5.2e-12 46.0 0.1 9.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) KIX_2 PF16987.5 XP_668485.1 - 0.025 14.6 1.4 11 6.1 0.1 3.4 3 0 0 3 3 3 0 KIX domain P4Ha_N PF08336.11 XP_668485.1 - 0.032 14.2 4.3 0.24 11.4 0.1 3.1 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Metallophos_2 PF12850.7 XP_668486.1 - 2.9e-17 63.4 0.0 3.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 XP_668486.1 - 0.0015 19.0 0.2 0.041 14.4 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aha1_N PF09229.11 XP_668487.1 - 1.5e-30 106.2 16.6 2.3e-22 79.7 3.0 2.7 3 0 0 3 3 3 2 Activator of Hsp90 ATPase, N-terminal SopE_GEF PF07487.13 XP_668487.1 - 0.16 12.1 1.3 0.29 11.2 0.9 1.6 1 1 0 1 1 1 0 SopE GEF domain LMBR1 PF04791.16 XP_668487.1 - 0.65 8.8 5.0 0.74 8.6 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LSM PF01423.22 XP_668488.1 - 2.2e-16 59.3 0.1 2.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 XP_668488.1 - 6.8e-05 22.9 0.0 7.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 XP_668488.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain SIR2 PF02146.17 XP_668489.1 - 4.1e-22 79.0 0.0 5.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1936 PF09151.10 XP_668489.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) TPP_enzyme_M PF00205.22 XP_668489.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Mistic PF11458.8 XP_668489.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Membrane-integrating protein Mistic IL8 PF00048.20 XP_668489.1 - 0.33 11.1 4.0 13 6.0 0.2 2.5 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like YfzA PF14118.6 XP_668490.1 - 0.019 15.4 3.0 0.075 13.4 0.2 2.2 2 0 0 2 2 2 0 YfzA-like protein HEAT PF02985.22 XP_668491.1 - 1.6e-07 31.0 0.1 0.099 13.0 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat Cnd1 PF12717.7 XP_668491.1 - 0.0033 17.5 0.8 2.8 8.0 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 XP_668491.1 - 0.07 13.7 0.1 14 6.3 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Phage_holin_3_3 PF16083.5 XP_668491.1 - 0.076 13.1 0.1 0.21 11.7 0.1 1.8 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III Med28 PF11594.8 XP_668491.1 - 0.11 12.5 1.7 2.1 8.4 1.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 HEAT_EZ PF13513.6 XP_668491.1 - 0.2 12.2 0.0 48 4.6 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat Pkinase PF00069.25 XP_668492.1 - 1.8e-09 37.3 0.1 6.5e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668492.1 - 0.059 12.7 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Tubulin PF00091.25 XP_668494.1 - 2.1e-69 233.7 0.0 5.1e-69 232.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 XP_668494.1 - 4.1e-43 146.5 1.0 4.1e-43 146.5 1.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 XP_668494.1 - 0.00022 21.5 0.0 0.0009 19.5 0.0 2.1 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.8 XP_668494.1 - 0.0018 18.7 0.1 0.0042 17.6 0.1 1.6 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Tubulin_2 PF13809.6 XP_668494.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like NPL4 PF05021.15 XP_668495.1 - 2.1e-31 109.4 0.0 8.4e-30 104.2 0.0 2.5 1 1 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 XP_668495.1 - 1.5e-21 76.7 0.7 4e-21 75.3 0.1 2.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.15 XP_668495.1 - 1.8e-06 28.2 0.0 4.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region ACP_syn_III_C PF08541.10 XP_668495.1 - 0.002 18.3 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ubiquitin PF00240.23 XP_668495.1 - 0.0027 17.4 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family BUD22 PF09073.10 XP_668496.1 - 0.00065 19.2 22.9 0.00074 19.0 22.9 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 XP_668496.1 - 0.019 14.4 26.0 0.025 14.0 26.0 1.1 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 XP_668496.1 - 0.057 11.6 10.8 0.064 11.4 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 XP_668496.1 - 0.11 10.7 20.2 0.14 10.4 20.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 XP_668496.1 - 0.12 11.1 15.6 0.19 10.4 15.6 1.4 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 XP_668496.1 - 0.22 10.1 39.3 0.34 9.4 39.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 XP_668496.1 - 0.28 9.4 28.4 0.35 9.0 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 XP_668496.1 - 0.29 10.9 21.2 0.45 10.3 21.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 XP_668496.1 - 1.2 7.9 8.8 1.8 7.3 8.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Raftlin PF15250.6 XP_668496.1 - 1.2 7.8 14.6 1.7 7.3 14.6 1.2 1 0 0 1 1 1 0 Raftlin PA26 PF04636.13 XP_668496.1 - 2 7.2 10.0 2.9 6.7 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2201_N PF13203.6 XP_668496.1 - 2.2 7.8 6.6 2.9 7.4 6.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.16 XP_668496.1 - 2.5 8.1 6.9 3.5 7.6 6.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 XP_668496.1 - 3.8 6.2 22.2 5.4 5.7 22.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Merozoite_SPAM PF07133.11 XP_668496.1 - 4.3 7.3 44.7 8 6.4 44.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Borrelia_P83 PF05262.11 XP_668496.1 - 4.4 5.7 21.1 5.8 5.3 21.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PTPRCAP PF15713.5 XP_668496.1 - 4.6 7.5 24.5 9 6.6 24.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SLC12 PF03522.15 XP_668496.1 - 5 6.0 17.6 7.4 5.5 17.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 XP_668496.1 - 5.3 5.9 12.0 9.7 5.1 12.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2457 PF10446.9 XP_668496.1 - 5.6 6.0 27.4 8 5.5 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Polyketide_cyc PF03364.20 XP_668497.1 - 2.1e-05 24.7 0.0 3.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cob_adeno_trans PF01923.18 XP_668498.1 - 0.0012 19.0 11.6 0.021 15.0 0.3 3.9 1 1 2 4 4 4 2 Cobalamin adenosyltransferase FapA PF03961.13 XP_668498.1 - 0.0013 17.4 15.2 0.0013 17.4 15.2 2.0 1 1 1 2 2 2 1 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 XP_668498.1 - 0.027 14.8 19.1 0.74 10.2 0.4 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF713 PF05218.14 XP_668498.1 - 0.58 9.9 15.7 0.95 9.2 5.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF713) DUF1411 PF07199.11 XP_668498.1 - 0.6 9.7 4.1 0.87 9.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) Fungal_trans_2 PF11951.8 XP_668498.1 - 3.5 6.3 6.9 0.8 8.5 0.1 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain GTP-bdg_M PF16360.5 XP_668498.1 - 5.6 7.6 8.0 9.9 6.8 5.0 2.8 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region Syntaxin-6_N PF09177.11 XP_668498.1 - 6.5 7.4 20.5 1.9 9.1 4.0 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal SPT16 PF08644.11 XP_668499.1 - 1.7e-42 145.1 0.5 1.7e-42 145.1 0.5 3.5 2 1 2 4 4 4 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 XP_668499.1 - 3.2e-17 62.7 0.0 8.6e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.24 XP_668499.1 - 2.5e-08 33.9 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Codanin-1_C PF15296.6 XP_668499.1 - 3.2 7.8 8.4 0.16 12.1 1.3 2.2 2 0 0 2 2 2 0 Codanin-1 C-terminus CDC45 PF02724.14 XP_668499.1 - 4.2 5.6 50.0 0.24 9.7 18.3 2.4 2 0 0 2 2 2 0 CDC45-like protein Sld5 PF05916.11 XP_668500.1 - 1.9e-05 25.1 0.1 2.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_15 PF00723.21 XP_668500.1 - 0.023 13.5 0.0 0.024 13.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 FAP206 PF12018.8 XP_668500.1 - 0.033 13.7 0.1 0.037 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function Adaptin_N PF01602.20 XP_668501.1 - 4.1e-77 259.9 15.6 6.3e-77 259.3 15.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 XP_668501.1 - 8.2e-29 100.7 0.2 6.7e-28 97.7 0.1 2.3 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 XP_668501.1 - 1.1e-23 83.5 0.0 2.7e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 XP_668501.1 - 1.8e-07 31.4 0.4 9.2e-05 22.8 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 XP_668501.1 - 4.8e-07 30.0 11.8 3.2e-05 24.0 0.0 4.7 1 1 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 XP_668501.1 - 3.3 8.2 10.8 8.9 6.9 0.3 5.7 6 0 0 6 6 6 0 HEAT repeat Pyr_redox_2 PF07992.14 XP_668502.1 - 5.7e-35 121.0 0.0 7.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 XP_668502.1 - 5.9e-07 30.0 0.1 5.3e-06 26.9 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SopE_GEF PF07487.13 XP_668502.1 - 0.01 15.9 0.3 8.7 6.4 0.1 2.9 3 0 0 3 3 3 0 SopE GEF domain Plasmo_rep PF12135.8 XP_668502.1 - 3.7 7.2 5.3 3.2 7.4 0.9 2.8 2 0 0 2 2 2 0 Plasmodium repeat family KH_1 PF00013.29 XP_668503.1 - 2.8e-18 65.5 14.1 1.4e-11 44.1 1.3 6.1 7 0 0 7 7 7 3 KH domain SLS PF14611.6 XP_668503.1 - 8.4e-08 32.3 16.3 0.00035 20.5 0.2 4.5 1 1 3 5 5 5 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 XP_668503.1 - 0.0002 21.1 1.5 0.0029 17.4 0.1 3.4 3 0 0 3 3 3 1 KH domain GyrB_insert PF18053.1 XP_668503.1 - 0.054 13.4 0.4 0.2 11.5 0.4 2.0 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain KH_4 PF13083.6 XP_668503.1 - 0.31 10.9 2.2 0.42 10.5 0.0 2.5 3 0 0 3 3 3 0 KH domain DUF2067 PF09840.9 XP_668503.1 - 1.4 8.5 10.6 0.49 9.9 0.2 4.8 5 1 0 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2067) EMP24_GP25L PF01105.24 XP_668504.1 - 1.2e-31 110.0 4.4 1.5e-31 109.8 4.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 XP_668504.1 - 0.0034 17.6 0.1 0.0051 17.0 0.1 1.2 1 0 0 1 1 1 1 SdrD B-like domain SMC_N PF02463.19 XP_668505.1 - 4.7e-61 206.0 49.7 1.9e-60 204.0 49.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 XP_668505.1 - 3.7e-20 72.4 1.0 1.3e-19 70.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 XP_668505.1 - 2.8e-15 56.9 25.4 1.1e-07 32.0 10.1 4.6 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 XP_668505.1 - 3.1e-15 57.2 1.3 3.1e-15 57.2 1.3 7.3 2 2 4 7 7 5 2 AAA domain AAA_15 PF13175.6 XP_668505.1 - 2.5e-10 40.6 9.0 2.5e-10 40.6 9.0 4.5 2 2 2 4 4 1 1 AAA ATPase domain AAA_29 PF13555.6 XP_668505.1 - 3.3e-07 30.0 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRE1 PF08647.11 XP_668505.1 - 0.0021 18.1 12.7 0.0021 18.1 12.7 10.2 5 3 5 11 11 10 2 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 XP_668505.1 - 0.035 14.6 0.0 0.035 14.6 0.0 6.6 3 2 1 5 5 3 0 ABC transporter Tropomyosin_1 PF12718.7 XP_668505.1 - 2.2 8.4 131.0 1.5 9.0 6.6 8.2 3 3 2 6 6 6 0 Tropomyosin like AAA_22 PF13401.6 XP_668505.1 - 4.4 7.6 8.2 0.88 9.8 0.0 4.0 4 1 0 4 4 4 0 AAA domain ApoO PF09769.9 XP_668505.1 - 7.2 6.6 8.6 20 5.2 0.1 5.1 5 0 0 5 5 5 0 Apolipoprotein O Pkinase PF00069.25 XP_668506.1 - 5.6e-70 235.7 0.0 8.7e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668506.1 - 5.7e-28 97.9 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 XP_668506.1 - 3.2e-21 73.2 6.6 9.3e-07 28.0 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 XP_668506.1 - 4.2e-20 72.0 2.2 2.7e-11 43.8 1.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 XP_668506.1 - 1.1e-15 56.1 6.2 0.00064 19.5 0.0 4.8 5 0 0 5 5 4 3 EF-hand domain EF-hand_8 PF13833.6 XP_668506.1 - 1.4e-15 56.9 4.6 0.0004 20.2 0.3 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 XP_668506.1 - 5.6e-12 44.6 8.1 0.00013 21.3 0.3 4.0 4 0 0 4 4 4 3 EF hand CBM_20 PF00686.19 XP_668506.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Starch binding domain EF-hand_9 PF14658.6 XP_668506.1 - 5.9e-07 29.7 0.2 0.00066 20.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 XP_668506.1 - 9.3e-05 22.7 0.4 3.8 7.9 0.1 3.4 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 XP_668506.1 - 0.00015 21.6 0.6 0.0088 16.0 0.2 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 XP_668506.1 - 0.00051 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 XP_668506.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dockerin_1 PF00404.18 XP_668506.1 - 0.12 12.6 1.6 1.3 9.3 0.4 2.9 2 1 1 3 3 2 0 Dockerin type I domain UDPGP PF01704.18 XP_668507.1 - 2.8e-21 75.7 0.0 5.1e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TRAPP PF04051.16 XP_668508.1 - 3.6e-32 111.1 0.0 4.4e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_trans_1_4 PF13692.6 XP_668509.1 - 1.6e-07 31.8 0.0 2.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 XP_668509.1 - 3.6e-05 23.4 0.0 0.00013 21.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Peptidase_C12 PF01088.21 XP_668511.1 - 1.3e-38 132.9 0.0 1.5e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UvrD-helicase PF00580.21 XP_668512.1 - 5.4e-53 180.6 3.4 5.4e-53 180.6 3.4 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 XP_668512.1 - 6.8e-42 144.1 13.8 4.4e-41 141.4 9.6 3.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 XP_668512.1 - 3.8e-24 85.7 0.0 1.3e-23 83.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 XP_668512.1 - 7.9e-11 41.6 0.2 9.8e-10 38.1 0.2 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 XP_668512.1 - 8.3e-06 25.6 0.0 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 XP_668512.1 - 0.0023 17.6 6.8 0.022 14.4 0.2 3.4 3 1 0 3 3 3 2 AAA domain ResIII PF04851.15 XP_668512.1 - 0.011 15.8 0.2 0.011 15.8 0.2 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 XP_668512.1 - 0.027 14.2 0.1 0.92 9.2 0.0 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 XP_668512.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF3223 PF11523.8 XP_668513.1 - 6.3e-18 65.4 1.9 4.2e-17 62.7 0.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) La PF05383.17 XP_668513.1 - 1.3e-14 54.0 0.3 5e-14 52.1 0.2 2.1 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 XP_668513.1 - 0.049 13.7 2.0 0.11 12.5 0.1 2.4 3 0 0 3 3 3 0 RNA binding motif AP2 PF00847.20 XP_668514.1 - 2.9e-12 46.6 3.1 5.7e-12 45.7 3.1 1.5 1 0 0 1 1 1 1 AP2 domain BLYB PF05289.11 XP_668515.1 - 0.0062 16.8 2.6 1.2 9.3 0.3 2.9 1 1 1 2 2 2 2 Borrelia hemolysin accessory protein DDHD PF02862.17 XP_668515.1 - 0.033 14.3 0.9 0.074 13.2 0.9 1.6 1 0 0 1 1 1 0 DDHD domain ABC1 PF03109.16 XP_668516.1 - 1.6e-26 92.8 0.0 9.1e-26 90.4 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Arm PF00514.23 XP_668517.1 - 2.8e-80 262.2 13.9 9.2e-13 47.8 0.0 10.1 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 XP_668517.1 - 5.1e-19 68.4 0.1 0.00032 21.1 0.0 6.1 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 XP_668517.1 - 4.8e-17 62.1 0.0 0.00095 19.5 0.0 5.5 2 2 4 6 6 6 5 HEAT repeats Arm_3 PF16186.5 XP_668517.1 - 1.8e-15 56.2 0.5 5.9e-15 54.6 0.5 1.9 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 XP_668517.1 - 5.4e-15 55.6 4.4 7.3e-14 52.0 3.8 2.4 2 0 0 2 2 2 1 Importin beta binding domain HEAT PF02985.22 XP_668517.1 - 2.2e-14 52.3 1.0 0.024 14.9 0.0 7.0 8 0 0 8 8 7 3 HEAT repeat Cnd1 PF12717.7 XP_668517.1 - 3.8e-05 23.8 0.0 0.055 13.5 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 XP_668517.1 - 0.0001 21.0 0.0 0.11 11.0 0.0 3.1 2 2 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 XP_668517.1 - 0.0039 17.3 0.0 6.6 6.9 0.0 4.1 3 2 2 5 5 5 1 V-ATPase subunit H ParcG PF10274.9 XP_668517.1 - 0.02 15.0 0.1 14 5.8 0.0 3.0 2 1 1 3 3 3 0 Parkin co-regulated protein Mo25 PF08569.11 XP_668517.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Mo25-like Atx10homo_assoc PF09759.9 XP_668517.1 - 0.13 12.3 0.1 29 4.7 0.0 3.4 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DnaJ-X PF14308.6 XP_668519.1 - 2.7e-47 161.0 6.3 5.9e-47 159.8 6.3 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 XP_668519.1 - 5.1e-24 84.2 6.1 1.2e-23 83.0 6.1 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 XP_668519.1 - 4.3e-06 27.0 0.1 1.8e-05 25.0 0.1 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF834 PF05754.14 XP_668519.1 - 0.21 11.7 4.0 0.69 10.0 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Antimicrobial_2 PF08023.12 XP_668519.1 - 0.61 10.7 3.6 3.8 8.1 1.6 2.8 2 0 0 2 2 2 0 Frog antimicrobial peptide PIP5K PF01504.18 XP_668520.1 - 4.9e-78 262.1 11.1 5.7e-78 261.9 8.3 2.4 2 2 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Methyltransf_31 PF13847.6 XP_668521.1 - 5.7e-15 55.4 0.0 8.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_668521.1 - 4e-12 46.6 0.0 6.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 XP_668521.1 - 1.4e-11 44.9 0.0 2.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_668521.1 - 1.7e-10 40.9 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 XP_668521.1 - 5.9e-10 39.8 0.0 1.8e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 XP_668521.1 - 2.5e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 XP_668521.1 - 5.5e-05 22.6 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 XP_668521.1 - 0.0003 20.0 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 XP_668521.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 XP_668521.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.15 XP_668521.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.6 XP_668521.1 - 0.15 13.1 0.0 0.26 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Kinesin PF00225.23 XP_668522.1 - 2.8e-91 305.9 6.2 4.6e-91 305.2 6.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 XP_668522.1 - 1.8e-18 66.9 2.1 6.1e-18 65.2 2.1 1.9 1 0 0 1 1 1 1 Microtubule binding PhoH PF02562.16 XP_668522.1 - 0.041 13.3 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 XP_668522.1 - 0.076 13.0 0.7 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit GEMIN8 PF15348.6 XP_668522.1 - 0.1 12.9 3.6 0.22 11.8 3.6 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF87 PF01935.17 XP_668522.1 - 2.8 8.0 9.6 13 5.8 0.2 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain EF-G-binding_N PF07299.11 XP_668522.1 - 6.4 7.4 8.3 0.46 11.0 0.3 3.3 3 1 1 4 4 4 0 Elongation factor G-binding protein, N-terminal SBDS PF01172.18 XP_668523.1 - 4e-33 113.3 0.2 4e-33 113.3 0.2 2.0 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 XP_668523.1 - 6.9e-26 90.5 3.2 1.1e-25 89.8 0.8 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain zf-met PF12874.7 XP_668523.1 - 0.016 15.6 1.9 0.055 13.9 1.9 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 XP_668523.1 - 0.29 11.5 2.2 0.75 10.2 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding tRNA_synthFbeta PF17759.1 XP_668524.1 - 4.9e-33 114.4 0.0 7.7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 XP_668524.1 - 4.4e-23 81.3 0.3 2.9e-22 78.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 XP_668524.1 - 3e-18 66.1 0.1 7e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 XP_668524.1 - 6.1e-10 39.3 0.1 7e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 tRNA synthetase B5 domain eIF-1a PF01176.19 XP_668525.1 - 7.4e-24 83.3 0.0 1.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PWI PF01480.17 XP_668526.1 - 7.2e-21 74.3 0.1 1.6e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 PWI domain Chordopox_G3 PF06129.12 XP_668526.1 - 0.32 11.7 4.3 11 6.8 0.1 3.2 4 0 0 4 4 4 0 Chordopoxvirus G3 protein Ribosomal_L26 PF16906.5 XP_668526.1 - 1.3 9.6 6.5 0.34 11.4 1.7 2.4 3 1 0 3 3 3 0 Ribosomal proteins L26 eukaryotic, L24P archaeal FOG_N PF15888.5 XP_668527.1 - 0.17 12.3 34.3 3.6 8.0 0.1 9.6 7 2 2 9 9 9 0 Folded gastrulation N-terminus CBM_14 PF01607.24 XP_668527.1 - 0.18 12.0 43.1 0.31 11.2 1.1 9.3 7 2 3 10 10 10 0 Chitin binding Peritrophin-A domain cEGF PF12662.7 XP_668527.1 - 0.25 11.3 32.3 1.5 8.8 0.5 9.9 10 0 0 10 10 10 0 Complement Clr-like EGF-like MCM_bind PF09739.9 XP_668528.1 - 8.3e-35 120.3 12.9 8.8e-35 120.2 8.8 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor RRM_1 PF00076.22 XP_668529.1 - 2.1e-06 27.4 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUC173 PF08161.12 XP_668530.1 - 2.8e-31 108.8 0.6 1.1e-28 100.3 0.0 3.7 3 1 0 3 3 3 2 NUC173 domain Brix PF04427.18 XP_668531.1 - 1.8e-38 132.6 0.0 2.4e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain NIF PF03031.18 XP_668532.1 - 4.3e-23 81.8 0.0 9.1e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DASH_Dad1 PF08649.10 XP_668532.1 - 0.23 11.7 0.3 0.23 11.7 0.3 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 PrmA PF06325.13 XP_668533.1 - 1.9e-10 40.7 0.1 2.8e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 XP_668533.1 - 6.4e-09 36.4 0.0 1.8e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 XP_668533.1 - 4.6e-08 33.6 0.0 1.5e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 XP_668533.1 - 4.8e-07 29.8 0.0 7.1e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 XP_668533.1 - 1.6e-06 28.0 0.5 4.7e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 XP_668533.1 - 3.6e-05 23.4 0.1 6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 XP_668533.1 - 0.00089 20.0 0.0 0.0022 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 XP_668533.1 - 0.0028 17.4 0.1 0.004 16.9 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 XP_668533.1 - 0.003 17.5 0.1 0.0064 16.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 XP_668533.1 - 0.0037 16.6 0.1 0.0056 16.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 XP_668533.1 - 0.0042 16.1 0.0 0.0093 14.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 XP_668533.1 - 0.032 14.1 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase FtsJ PF01728.19 XP_668533.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 XP_668533.1 - 0.058 13.1 0.7 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 Lysine methyltransferase DUF3458_C PF17432.2 XP_668534.1 - 6.8e-54 183.4 0.0 9.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 XP_668534.1 - 2e-44 151.8 0.0 3.2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 XP_668534.1 - 7.5e-24 84.0 0.0 2e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 XP_668534.1 - 3.9e-09 37.0 0.0 7.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_EZ PF13513.6 XP_668535.1 - 1.9e-17 63.4 2.8 9.9e-09 35.5 0.0 6.6 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.22 XP_668535.1 - 2.2e-13 49.2 8.1 0.00087 19.4 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 XP_668535.1 - 5.5e-08 33.1 0.0 0.062 13.7 0.0 5.5 4 1 1 5 5 5 2 HEAT repeats Arm PF00514.23 XP_668535.1 - 5.4e-05 23.1 5.6 0.014 15.4 0.6 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 XP_668535.1 - 0.0024 17.7 0.1 0.68 9.9 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) IBN_N PF03810.19 XP_668535.1 - 0.0024 17.7 0.1 0.024 14.6 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain TAF6_C PF07571.13 XP_668535.1 - 0.1 12.9 0.0 1.2 9.5 0.0 2.8 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Ribosomal_L22 PF00237.19 XP_668536.1 - 1.4e-29 102.3 0.0 2.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e tRNA-synt_1g PF09334.11 XP_668537.1 - 1.9e-96 323.2 1.6 3.3e-54 184.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 XP_668537.1 - 4.6e-31 107.7 4.1 1.9e-16 59.4 0.2 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 XP_668537.1 - 7.7e-14 51.7 0.0 2.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 XP_668537.1 - 0.00047 19.2 0.0 0.57 9.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 XP_668537.1 - 0.025 14.6 0.1 0.087 12.8 0.1 1.9 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-RING_2 PF13639.6 XP_668538.1 - 1.7e-11 44.3 9.1 3.6e-11 43.2 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 XP_668538.1 - 1.3e-08 34.4 8.9 3.6e-08 33.0 8.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 XP_668538.1 - 7.3e-08 32.6 9.8 5.9e-07 29.7 9.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 XP_668538.1 - 2.9e-07 30.2 8.7 6.5e-07 29.1 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 XP_668538.1 - 1.3e-05 25.0 7.9 2.7e-05 23.9 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_668538.1 - 6e-05 22.9 5.8 6e-05 22.9 5.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 XP_668538.1 - 0.00065 19.5 5.9 0.00065 19.5 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_668538.1 - 0.0007 19.6 7.6 0.0019 18.1 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 XP_668538.1 - 0.0014 18.2 5.6 0.0032 17.0 5.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 XP_668538.1 - 0.013 15.3 7.9 0.013 15.3 7.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_9 PF13901.6 XP_668538.1 - 0.017 15.1 5.0 0.61 10.0 3.7 2.7 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-ANAPC11 PF12861.7 XP_668538.1 - 0.045 13.8 4.1 0.15 12.1 4.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HTH_36 PF13730.6 XP_668538.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain zinc_ribbon_16 PF17034.5 XP_668538.1 - 0.079 13.2 4.3 0.044 14.0 1.8 1.9 2 0 0 2 2 2 0 Zinc-ribbon like family PH_2 PF08458.10 XP_668538.1 - 0.14 12.5 0.2 0.29 11.5 0.2 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region zf-C3H2C3 PF17122.5 XP_668538.1 - 0.23 11.5 5.0 0.55 10.3 5.0 1.7 1 0 0 1 1 1 0 Zinc-finger C1_1 PF00130.22 XP_668538.1 - 0.32 10.9 5.9 0.16 11.9 2.9 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 XP_668538.1 - 0.36 10.7 6.7 0.77 9.7 6.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 XP_668538.1 - 0.36 11.2 2.6 0.78 10.1 2.6 1.5 1 0 0 1 1 1 0 RING-like domain C1_2 PF03107.16 XP_668538.1 - 0.38 11.1 3.9 1.1 9.7 3.9 1.8 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 XP_668538.1 - 0.44 10.7 4.2 1.1 9.4 4.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 XP_668538.1 - 0.56 10.4 6.3 1.3 9.2 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain Ribosomal_L34e PF01199.18 XP_668539.1 - 4.2e-38 129.5 5.6 4.2e-38 129.5 5.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e SelP_N PF04592.14 XP_668539.1 - 0.13 11.7 1.8 0.33 10.3 0.4 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF3090 PF11290.8 XP_668539.1 - 1.2 8.9 7.2 12 5.7 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3090) Glutaredoxin PF00462.24 XP_668539.1 - 1.3 9.3 4.7 4 7.7 0.2 2.4 2 1 0 2 2 2 0 Glutaredoxin PPDFL PF15060.6 XP_668541.1 - 0.012 16.1 0.2 0.032 14.8 0.0 1.7 2 0 0 2 2 2 0 Differentiation and proliferation regulator DUF5344 PF17279.2 XP_668545.1 - 0.15 12.7 0.4 0.15 12.7 0.4 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5344) CAP PF00188.26 XP_668546.1 - 2.2e-57 193.3 6.8 1.7e-17 64.4 0.0 4.7 4 0 0 4 4 4 4 Cysteine-rich secretory protein family PLA2G12 PF06951.11 XP_668547.1 - 0.029 14.3 1.0 1.3 8.9 0.1 2.3 1 1 1 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) NblA PF04485.12 XP_668547.1 - 0.055 13.9 1.1 0.3 11.5 0.1 2.3 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA PriX PF18689.1 XP_668547.1 - 0.15 12.4 3.7 0.59 10.5 0.5 2.9 2 1 1 3 3 3 0 Primase X MFS_1 PF07690.16 XP_668548.1 - 1.1e-21 77.2 35.1 1.1e-21 77.2 35.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 XP_668548.1 - 0.12 12.6 10.8 5.7 7.3 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) His_Phos_1 PF00300.22 XP_668550.1 - 1.5e-37 129.2 0.0 1.1e-28 100.3 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) NIF PF03031.18 XP_668552.1 - 8.6e-25 87.3 0.1 1.6e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 XP_668552.1 - 3.9e-07 30.3 0.0 1.4e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 XP_668552.1 - 0.00016 21.5 0.1 0.00057 19.8 0.1 2.0 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 XP_668552.1 - 0.0024 18.1 0.1 0.0053 17.0 0.1 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Band_7 PF01145.25 XP_668553.1 - 5.1e-12 46.2 5.6 1.2e-11 45.0 5.6 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 XP_668553.1 - 4.4e-06 26.0 2.1 5.7e-06 25.6 2.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 XP_668553.1 - 0.06 13.0 0.3 0.092 12.4 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family CAP_N PF01213.19 XP_668554.1 - 0.16 11.4 0.4 0.24 10.9 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cpn60_TCP1 PF00118.24 XP_668555.1 - 1e-163 545.5 1.1 1.2e-163 545.3 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpb4 PF03874.16 XP_668556.1 - 2.7e-15 56.8 0.8 5e-15 55.9 0.8 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 Cation_ATPase_C PF00689.21 XP_668557.1 - 9.8e-50 168.8 6.0 9.8e-50 168.8 6.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 XP_668557.1 - 1.3e-49 168.2 1.5 1.3e-49 168.2 1.5 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 XP_668557.1 - 6.4e-22 78.9 0.0 1.2e-11 45.3 0.0 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 XP_668557.1 - 2.8e-16 59.4 0.0 6.2e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 XP_668557.1 - 1.3e-14 53.6 0.0 3.9e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 XP_668557.1 - 0.00011 22.1 1.4 0.013 15.3 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 XP_668557.1 - 0.0073 16.7 0.0 0.062 13.7 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 XP_668557.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Clat_adaptor_s PF01217.20 XP_668558.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain zf-RING_2 PF13639.6 XP_668559.1 - 1.3e-11 44.6 9.8 2.6e-11 43.7 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 XP_668559.1 - 3.1e-08 33.8 6.1 7.9e-08 32.5 6.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 XP_668559.1 - 9.7e-08 31.6 3.8 9.7e-08 31.6 3.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 XP_668559.1 - 4.4e-05 23.2 8.3 8.3e-05 22.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 XP_668559.1 - 5.6e-05 22.9 7.8 0.00018 21.3 7.8 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 XP_668559.1 - 5.9e-05 22.9 6.4 0.00012 22.0 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 XP_668559.1 - 0.00042 20.1 11.0 0.011 15.6 4.6 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 XP_668559.1 - 0.00068 19.6 1.8 0.00068 19.6 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 XP_668559.1 - 0.0012 18.6 8.3 0.0027 17.6 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 XP_668559.1 - 0.0066 16.5 3.2 0.0066 16.5 3.2 2.1 3 0 0 3 3 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 XP_668559.1 - 0.019 14.6 6.2 0.045 13.4 5.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 XP_668559.1 - 0.023 14.9 5.0 0.1 12.8 5.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.11 XP_668559.1 - 0.044 13.8 1.3 0.089 12.8 1.3 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain TMEM154 PF15102.6 XP_668559.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.5 3 0 0 3 3 3 0 TMEM154 protein family Transglut_core2 PF13369.6 XP_668559.1 - 0.057 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily zf_Rg PF17915.1 XP_668559.1 - 0.068 12.6 1.9 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Reverse gyrase zinc finger RINGv PF12906.7 XP_668559.1 - 0.18 12.0 8.1 0.38 10.9 8.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.12 XP_668559.1 - 7.9 6.9 8.4 7.8e+02 0.5 8.5 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Glycos_transf_2 PF00535.26 XP_668560.1 - 9.6e-27 93.9 0.0 1.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 XP_668560.1 - 9.6e-07 28.9 0.0 2.7e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 XP_668560.1 - 4e-06 26.4 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.8 XP_668560.1 - 0.15 11.5 0.5 0.8 9.1 0.5 1.9 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) PP2C PF00481.21 XP_668561.1 - 4.1e-23 82.3 0.0 7.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 XP_668561.1 - 0.0073 16.0 0.0 0.062 12.9 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 XP_668562.1 - 4.2e-20 71.7 12.6 1.5e-05 25.7 0.4 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_668562.1 - 3.9e-14 52.7 0.5 0.00037 20.7 0.1 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 XP_668562.1 - 4e-06 26.9 0.0 0.00057 19.8 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Methyltr_RsmB-F PF01189.17 XP_668563.1 - 1.7e-22 80.0 0.0 2.6e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F UPF0449 PF15136.6 XP_668563.1 - 0.0026 18.2 0.4 0.0054 17.2 0.4 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 CSN7a_helixI PF18392.1 XP_668563.1 - 0.025 14.5 0.4 0.067 13.1 0.4 1.7 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain FtsJ PF01728.19 XP_668563.1 - 0.05 13.7 0.0 0.097 12.8 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4965 PF16335.5 XP_668563.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) Castor1_N PF18700.1 XP_668563.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Methyltransf_31 PF13847.6 XP_668563.1 - 0.13 12.1 0.4 13 5.6 0.1 2.9 3 0 0 3 3 3 0 Methyltransferase domain Glycos_transf_2 PF00535.26 XP_668564.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Csm1_B PF18211.1 XP_668564.1 - 0.04 13.8 0.7 5.9 6.8 0.0 2.7 1 1 1 2 2 2 0 Csm1 subunit domain B BING4CT PF08149.11 XP_668565.1 - 1.5e-33 114.5 0.0 3.4e-30 103.7 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.32 XP_668565.1 - 0.0006 20.6 3.6 12 7.0 0.1 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_668565.1 - 0.0045 17.3 0.0 3.4 8.0 0.0 3.7 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 XP_668565.1 - 0.047 13.0 0.2 0.62 9.3 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain RINGv PF12906.7 XP_668566.1 - 6.2e-11 42.2 1.6 6.2e-11 42.2 1.6 2.3 2 0 0 2 2 2 1 RING-variant domain FHA PF00498.26 XP_668566.1 - 1e-06 29.0 2.5 2.6e-06 27.7 0.1 2.8 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 XP_668566.1 - 0.06 13.7 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain CLASP_N PF12348.8 XP_668567.1 - 1.6e-06 27.8 0.7 5.3e-06 26.2 0.7 1.8 1 1 0 1 1 1 1 CLASP N terminal DCB PF16213.5 XP_668567.1 - 0.14 11.8 3.8 0.12 12.0 1.6 2.0 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Thioredoxin PF00085.20 XP_668568.1 - 1.4e-52 176.0 0.3 3.1e-28 97.8 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 XP_668568.1 - 1.2e-09 38.3 0.6 5e-05 23.3 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 XP_668568.1 - 9e-08 31.8 0.2 1.6e-05 24.4 0.1 2.7 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 XP_668568.1 - 8.8e-07 29.2 0.1 0.0075 16.6 0.0 3.9 2 2 2 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 XP_668568.1 - 1.5e-06 28.6 3.0 0.11 12.9 0.1 4.4 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 XP_668568.1 - 2.2e-06 27.8 0.1 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 XP_668568.1 - 1.7e-05 24.7 0.1 0.0069 16.3 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 XP_668568.1 - 0.00063 19.6 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 XP_668568.1 - 0.0015 18.6 0.0 0.059 13.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 XP_668568.1 - 0.0045 17.2 1.1 0.064 13.4 0.4 2.8 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.6 XP_668568.1 - 0.006 16.3 0.0 5.4 6.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 XP_668568.1 - 0.013 15.2 0.1 0.45 10.2 0.0 2.7 3 0 0 3 3 3 0 Redoxin DSBA PF01323.20 XP_668568.1 - 0.037 13.8 0.4 1.9 8.2 0.0 3.1 2 2 1 3 3 3 0 DSBA-like thioredoxin domain HyaE PF07449.11 XP_668568.1 - 0.094 12.7 0.0 1.9 8.5 0.0 2.6 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE ArsA_ATPase PF02374.15 XP_668569.1 - 4.9e-52 177.0 1.7 2.1e-46 158.5 0.3 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase Palm_thioest PF02089.15 XP_668569.1 - 0.0094 15.8 1.1 0.02 14.8 0.8 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Plk4_PB1 PF18190.1 XP_668569.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 SRP72 PF08492.12 XP_668570.1 - 5.5e-13 49.1 7.2 5.5e-13 49.1 7.2 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 XP_668570.1 - 3e-11 43.4 1.0 3e-11 43.4 1.0 3.1 2 1 0 2 2 2 1 Putative TPR-like repeat ANAPC3 PF12895.7 XP_668570.1 - 2.2e-07 31.0 10.3 0.037 14.3 0.4 5.2 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 XP_668570.1 - 2.6e-07 31.0 3.4 0.27 11.8 0.1 6.2 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668570.1 - 1e-05 25.3 7.8 3.8 7.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 XP_668570.1 - 0.0044 17.7 0.0 64 4.8 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668570.1 - 0.0052 16.6 7.7 1.9 8.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 XP_668570.1 - 0.0074 16.9 2.2 44 5.0 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 XP_668570.1 - 0.042 13.5 0.0 0.17 11.5 0.0 2.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) NARP1 PF12569.8 XP_668570.1 - 0.092 11.6 4.7 2.2 7.1 0.1 3.2 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Csm2_III-A PF03750.13 XP_668570.1 - 0.46 11.3 3.8 2 9.3 0.1 3.2 3 0 0 3 3 3 0 Csm2 Type III-A PPR PF01535.20 XP_668570.1 - 1.7 9.1 4.1 16 6.1 0.1 4.9 6 1 1 7 7 5 0 PPR repeat TPR_8 PF13181.6 XP_668570.1 - 4.5 7.7 15.1 2.9 8.3 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Ribosomal_L38e PF01781.18 XP_668571.1 - 7.9e-29 99.6 3.4 9.1e-29 99.4 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NPR3 PF03666.13 XP_668573.1 - 0.15 10.8 5.0 0.19 10.5 5.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM163 PF15069.6 XP_668573.1 - 0.62 10.5 4.6 0.96 9.9 3.6 1.7 2 0 0 2 2 2 0 FAM163 family Zip PF02535.22 XP_668573.1 - 1 8.5 2.5 1.1 8.3 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 XP_668573.1 - 6.8 5.3 6.3 8.8 5.0 6.3 1.1 1 0 0 1 1 1 0 Presenilin ER_lumen_recept PF00810.18 XP_668575.1 - 1.5e-15 58.3 4.8 1.5e-15 58.3 4.8 2.1 2 2 0 2 2 2 1 ER lumen protein retaining receptor SRP_SPB PF02978.19 XP_668576.1 - 3.4e-32 111.0 3.6 3.4e-32 111.0 3.6 2.7 3 0 0 3 3 3 1 Signal peptide binding domain SRP54 PF00448.22 XP_668576.1 - 6.1e-28 97.8 0.1 2.9e-27 95.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Methyltr_RsmB-F PF01189.17 XP_668577.1 - 3.6e-40 137.7 0.0 1.6e-39 135.7 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 XP_668577.1 - 0.0039 17.3 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1500 PF07389.12 XP_668577.1 - 0.082 13.0 0.0 0.31 11.1 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1500) RRM_1 PF00076.22 XP_668578.1 - 2.5e-17 62.5 0.1 4e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 XP_668578.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 XP_668578.1 - 0.0048 17.1 0.3 0.011 16.0 0.0 1.8 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 XP_668578.1 - 0.0082 16.2 0.1 0.021 14.9 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 XP_668578.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3882 PF07066.11 XP_668578.1 - 0.042 13.9 0.3 0.08 13.0 0.0 1.7 1 1 1 2 2 2 0 Lactococcus phage M3 protein Nic96 PF04097.14 XP_668579.1 - 6.5e-10 38.1 7.0 6e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 Nup93/Nic96 DUF1617 PF07761.12 XP_668579.1 - 0.017 15.2 0.2 0.084 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) DMAP1_like PF17024.5 XP_668579.1 - 0.74 10.0 4.8 0.56 10.3 0.6 3.0 3 0 0 3 3 3 0 Putative DMAP1-like Ribosomal_L10 PF00466.20 XP_668580.1 - 7.6e-17 61.3 0.5 1.3e-16 60.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 XP_668580.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P UDG PF03167.19 XP_668581.1 - 5.5e-07 29.7 0.0 9.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ECM1 PF05782.11 XP_668581.1 - 0.011 14.7 0.2 0.018 14.0 0.2 1.3 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) WSD PF15613.6 XP_668582.1 - 3.5e-05 24.2 0.0 0.00024 21.5 0.0 2.5 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DNMT1-RFD PF12047.8 XP_668582.1 - 0.006 16.6 3.4 0.011 15.8 0.2 3.0 3 0 0 3 3 3 1 Cytosine specific DNA methyltransferase replication foci domain Lactamase_B_4 PF13691.6 XP_668583.1 - 5.5e-10 38.8 0.0 3e-09 36.4 0.0 2.3 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 XP_668583.1 - 2.4e-08 33.7 0.0 0.0026 17.3 0.0 2.7 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 XP_668583.1 - 5.6e-06 25.9 0.2 0.045 13.2 0.1 2.6 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 XP_668583.1 - 0.0001 22.4 0.0 0.00027 21.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TaqI_C PF12950.7 XP_668584.1 - 0.022 14.8 1.0 0.025 14.6 1.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain DUF3978 PF13123.6 XP_668584.1 - 0.054 13.2 1.5 0.073 12.8 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3978) DHHC PF01529.20 XP_668585.1 - 7.1e-34 116.8 14.0 7.1e-34 116.8 14.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-ribbon_3 PF13248.6 XP_668585.1 - 0.25 10.8 7.6 0.76 9.3 3.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF5366 PF17328.2 XP_668585.1 - 0.32 11.1 16.6 0.09 12.9 3.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5366) tRNA-synt_2 PF00152.20 XP_668587.1 - 5.8e-20 71.6 0.0 6.3e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 XP_668587.1 - 0.076 12.5 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 XP_668588.1 - 1.4e-44 152.5 0.2 2.2e-44 151.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Peptidase_S49_N PF08496.10 XP_668588.1 - 0.029 14.4 3.2 0.045 13.8 3.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NOB1_Zn_bind PF08772.11 XP_668589.1 - 6.5e-22 77.5 2.0 1.4e-21 76.4 2.0 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 XP_668589.1 - 1.1e-20 73.9 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease SDA1 PF05285.12 XP_668589.1 - 1.9 7.9 16.6 2.6 7.4 16.6 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 XP_668589.1 - 2.2 7.0 3.5 2.8 6.6 3.5 1.1 1 0 0 1 1 1 0 Presenilin SURF2 PF05477.11 XP_668590.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) His_Phos_2 PF00328.22 XP_668592.1 - 5.8e-50 170.7 2.7 3.4e-49 168.2 2.7 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 XP_668592.1 - 3.6e-35 120.0 0.3 2e-34 117.6 0.3 2.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 XP_668592.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NSs PF11073.8 XP_668592.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like tRNA-synt_1b PF00579.25 XP_668593.1 - 4e-21 75.6 0.0 7.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) P30 PF07390.11 XP_668593.1 - 0.037 14.1 1.1 0.086 12.9 1.1 1.6 1 0 0 1 1 1 0 Mycoplasma P30 protein DUF5074 PF16819.5 XP_668593.1 - 0.049 13.7 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) CBS PF00571.28 XP_668594.1 - 0.054 13.9 0.0 0.29 11.6 0.0 2.2 3 0 0 3 3 3 0 CBS domain dCMP_cyt_deam_1 PF00383.23 XP_668595.1 - 1.2e-11 44.4 0.0 2.8e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 XP_668595.1 - 1.7e-06 27.9 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase DUF4108 PF13390.6 XP_668595.1 - 0.046 13.6 2.4 0.068 13.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) Ribosomal_S27e PF01667.17 XP_668596.1 - 7.4e-26 89.6 6.2 9.2e-26 89.3 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Prok-RING_1 PF14446.6 XP_668596.1 - 0.19 11.7 3.9 0.3 11.0 3.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HTH_36 PF13730.6 XP_668597.1 - 0.048 13.6 0.4 1.9 8.5 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain TPR_1 PF00515.28 XP_668598.1 - 1.5e-15 56.2 2.7 0.011 15.5 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 XP_668598.1 - 4.1e-11 42.1 18.0 0.17 12.1 0.2 7.9 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668598.1 - 2.3e-10 39.8 12.1 0.32 11.3 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 XP_668598.1 - 1.2e-08 35.3 2.0 0.09 13.3 0.0 5.6 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 XP_668598.1 - 2.3e-07 30.7 12.0 0.0024 18.1 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 XP_668598.1 - 3.7e-07 30.4 14.8 0.035 14.4 0.7 6.8 4 1 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 XP_668598.1 - 5.9e-06 26.7 4.8 18 6.5 0.0 7.1 4 1 3 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 XP_668598.1 - 1.3e-05 25.3 0.0 0.14 12.3 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 XP_668598.1 - 1.9e-05 25.2 3.9 0.03 15.0 0.1 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_668598.1 - 3.9e-05 23.8 17.0 0.07 13.4 0.3 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 XP_668598.1 - 0.0001 22.0 8.2 0.24 11.5 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 XP_668598.1 - 0.00026 20.6 0.1 0.00026 20.6 0.1 5.7 8 1 1 9 9 8 2 TPR repeat ANAPC8 PF04049.13 XP_668598.1 - 0.0012 18.9 0.1 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_6 PF13174.6 XP_668598.1 - 0.0024 18.4 7.9 13 6.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 XP_668598.1 - 0.24 11.5 4.8 28 4.9 0.0 5.3 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 XP_668598.1 - 1.3 9.0 5.9 89 3.2 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 XP_668598.1 - 5.4 7.2 5.9 2.9 8.0 0.0 3.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain PhoD PF09423.10 XP_668599.1 - 1.8e-16 60.1 0.0 3.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Cgr1 PF03879.14 XP_668600.1 - 0.0011 19.3 26.3 0.0014 19.0 26.3 1.1 1 0 0 1 1 1 1 Cgr1 family CRF PF00473.17 XP_668600.1 - 1.3 9.2 4.0 3.5 7.8 4.0 1.9 1 1 0 1 1 1 0 Corticotropin-releasing factor family RecT PF03837.14 XP_668600.1 - 9.3 5.7 10.9 8.6 5.8 6.8 2.4 1 1 0 2 2 2 0 RecT family DUF3523 PF12037.8 XP_668601.1 - 5.1e-76 255.6 22.5 7.4e-76 255.0 22.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 XP_668601.1 - 3.9e-23 82.3 0.0 8.1e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 XP_668601.1 - 0.00091 19.6 0.2 0.15 12.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 XP_668601.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 XP_668601.1 - 0.0033 17.2 0.0 0.0099 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zot PF05707.12 XP_668601.1 - 0.0034 17.0 0.0 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 XP_668601.1 - 0.0054 16.9 2.1 0.0085 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 XP_668601.1 - 0.0079 15.7 0.2 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 XP_668601.1 - 0.0085 15.5 0.0 0.028 13.8 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_lid_3 PF17862.1 XP_668601.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain AAA_22 PF13401.6 XP_668601.1 - 0.018 15.3 2.6 0.12 12.6 0.0 3.0 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 XP_668601.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 XP_668601.1 - 0.02 14.9 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 XP_668601.1 - 0.049 13.6 0.1 0.049 13.6 0.1 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 XP_668601.1 - 0.075 13.2 0.1 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 XP_668601.1 - 0.078 13.5 0.0 0.078 13.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 XP_668601.1 - 0.14 12.5 0.1 0.41 11.1 0.1 1.8 1 0 0 1 1 1 0 RNA helicase Transthyretin PF00576.21 XP_668601.1 - 0.15 12.8 1.4 0.37 11.5 1.4 1.6 1 0 0 1 1 1 0 HIUase/Transthyretin family AAA_11 PF13086.6 XP_668601.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.1 2 1 0 2 2 1 0 AAA domain SbmA_BacA PF05992.12 XP_668603.1 - 2.4e-50 171.8 13.9 3.1e-50 171.4 13.9 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 XP_668603.1 - 2.7e-05 23.7 8.9 2.7e-05 23.7 8.9 2.3 2 1 0 2 2 2 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 XP_668604.1 - 1.7e-40 139.4 8.0 2e-40 139.1 8.0 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 XP_668604.1 - 2.5e-05 23.8 5.8 7.4e-05 22.3 5.8 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 MIF4G PF02854.19 XP_668604.1 - 0.14 11.8 2.4 1.6 8.3 0.4 2.2 2 0 0 2 2 2 0 MIF4G domain EpoR_lig-bind PF09067.10 XP_668604.1 - 0.14 12.3 0.3 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding DUF2207 PF09972.9 XP_668604.1 - 0.38 9.4 2.5 0.55 8.9 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TssO PF17561.2 XP_668605.1 - 0.042 13.9 0.5 0.083 13.0 0.2 1.6 1 1 1 2 2 2 0 Type VI secretion system, TssO DUF5472 PF17566.2 XP_668605.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5472) CDT1_C PF16679.5 XP_668605.1 - 0.11 13.0 0.2 0.2 12.1 0.2 1.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain CRAL_TRIO PF00650.20 XP_668606.1 - 1.2e-07 31.6 0.1 2.7e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain HTH_Tnp_Tc3_1 PF11427.8 XP_668606.1 - 0.0077 16.1 1.1 1 9.3 0.1 3.4 3 0 0 3 3 3 1 Tc3 transposase UME PF08064.13 XP_668606.1 - 0.31 11.0 2.1 0.53 10.2 0.1 2.5 3 0 0 3 3 3 0 UME (NUC010) domain Dicty_CAD PF05720.12 XP_668608.1 - 0.055 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Cell-cell adhesion domain Pkinase PF00069.25 XP_668609.1 - 1.1e-43 149.5 0.0 5.1e-43 147.3 0.0 2.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668609.1 - 2.2e-22 79.6 0.0 3.1e-19 69.3 0.0 3.6 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 XP_668610.1 - 2.9e-39 135.0 1.7 8e-38 130.3 1.7 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668610.1 - 3e-12 46.4 0.0 7.3e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 XP_668610.1 - 0.00088 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 XP_668610.1 - 0.039 13.5 2.5 0.032 13.8 0.7 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ricin_B_lectin PF00652.22 XP_668612.1 - 5.8e-07 29.8 0.3 0.00013 22.2 0.1 3.5 3 1 1 4 4 4 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 XP_668612.1 - 0.00021 20.9 0.4 0.00053 19.6 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 XP_668612.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 MliC PF09864.9 XP_668612.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Rgp1 PF08737.10 XP_668612.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Rgp1 IDH PF03971.14 XP_668612.1 - 0.18 10.2 0.1 0.26 9.7 0.1 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase CAF1C_H4-bd PF12265.8 XP_668615.1 - 2.8e-13 49.9 1.5 2.3e-12 47.0 0.3 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 XP_668615.1 - 2.2e-11 44.1 11.6 7.1e-06 26.7 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_668615.1 - 0.00014 22.1 0.2 0.038 14.3 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 XP_668615.1 - 0.001 19.0 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Mob1_phocein PF03637.17 XP_668617.1 - 2.5e-11 43.9 0.0 2.7e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family PH PF00169.29 XP_668619.1 - 1.8e-12 47.7 0.0 5.6e-11 42.9 0.0 3.1 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 XP_668619.1 - 0.0035 17.6 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 XP_668619.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.25 XP_668620.1 - 6.4e-69 232.3 0.0 1.1e-68 231.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 XP_668620.1 - 1.8e-40 138.9 0.0 3.3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 XP_668620.1 - 3e-32 110.9 1.4 8.9e-11 42.1 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 XP_668620.1 - 5.4e-31 103.8 11.0 1.1e-05 24.6 0.1 6.9 7 0 0 7 7 6 5 EF hand EF-hand_6 PF13405.6 XP_668620.1 - 5.8e-28 94.4 8.6 3.2e-05 23.5 0.1 6.9 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 XP_668620.1 - 1.6e-19 69.5 6.8 1.4e-05 24.9 0.2 5.5 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 XP_668620.1 - 7.2e-18 63.2 4.3 1.7e-06 27.3 0.2 5.0 5 0 0 5 5 5 3 EF hand Kdo PF06293.14 XP_668620.1 - 4.3e-06 26.2 0.3 8.2e-06 25.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 XP_668620.1 - 5e-06 26.8 2.2 0.039 14.3 0.0 3.9 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 XP_668620.1 - 4.8e-05 23.3 2.6 0.81 9.7 0.0 4.7 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 XP_668620.1 - 5.5e-05 22.6 0.2 0.00032 20.1 0.2 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 XP_668620.1 - 6.6e-05 21.8 0.4 0.00011 21.1 0.4 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 XP_668620.1 - 0.0002 20.5 0.5 0.00039 19.5 0.5 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 XP_668620.1 - 0.0047 16.5 0.1 0.014 15.0 0.1 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 XP_668620.1 - 0.0061 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 XP_668620.1 - 0.0069 16.3 0.1 0.41 10.5 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_10 PF14788.6 XP_668620.1 - 0.015 15.1 3.1 0.11 12.4 0.0 3.9 5 0 0 5 5 5 0 EF hand NOC3p PF07540.11 XP_668621.1 - 8.1e-15 55.1 0.2 7.7e-14 51.9 0.0 2.7 2 0 0 2 2 2 1 Nucleolar complex-associated protein Kri1 PF05178.12 XP_668621.1 - 0.17 12.5 3.8 0.5 10.9 3.8 1.8 1 0 0 1 1 1 0 KRI1-like family PGM_PMM_I PF02878.16 XP_668623.1 - 2.2e-14 53.3 0.0 3.2e-07 30.2 0.0 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 XP_668623.1 - 3.1e-06 27.3 0.0 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 XP_668623.1 - 3.7e-05 24.3 0.0 0.00046 20.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II IMCp PF12314.8 XP_668624.1 - 1.9e-08 34.5 54.4 8.9e-06 25.9 31.5 3.8 1 1 3 4 4 4 2 Inner membrane complex protein PsbU PF06514.11 XP_668624.1 - 0.076 13.0 0.8 0.18 11.8 0.5 1.8 1 1 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) IMCp PF12314.8 XP_668625.1 - 1.2e-12 47.9 33.9 1.2e-12 47.9 33.9 3.1 2 1 0 2 2 2 1 Inner membrane complex protein DUF2476 PF10630.9 XP_668625.1 - 0.018 15.2 0.3 0.053 13.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2476) GATA PF00320.27 XP_668626.1 - 0.23 11.1 7.1 0.16 11.6 0.5 2.4 2 0 0 2 2 2 0 GATA zinc finger Prok-E2_C PF14459.6 XP_668626.1 - 2.6 8.2 4.3 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family C HSP70 PF00012.20 XP_668627.1 - 7.4e-115 384.4 2.1 1.2e-114 383.7 0.1 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 XP_668627.1 - 0.001 18.0 3.5 0.0017 17.2 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein Spectrin_like PF18373.1 XP_668627.1 - 2.6 8.2 6.3 0.79 9.8 0.1 3.2 3 1 1 4 4 4 0 Spectrin like domain TRM PF02005.16 XP_668628.1 - 1.6e-73 248.1 0.2 8.2e-47 160.2 0.4 2.0 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 XP_668628.1 - 0.054 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 XP_668628.1 - 0.09 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 XP_668628.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein NIF PF03031.18 XP_668629.1 - 5.8e-43 146.3 2.1 3.4e-42 143.9 0.5 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Pkinase PF00069.25 XP_668630.1 - 0.0027 17.1 0.7 2 7.7 0.1 2.7 2 0 0 2 2 2 2 Protein kinase domain DUF1957 PF09210.11 XP_668630.1 - 0.15 12.5 1.7 12 6.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) JAKMIP_CC3 PF16034.5 XP_668630.1 - 1.9 8.4 5.4 0.72 9.8 0.2 2.7 2 1 1 3 3 3 0 JAKMIP CC3 domain Telomerase_RBD PF12009.8 XP_668630.1 - 3.9 7.6 7.2 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain Histone PF00125.24 XP_668631.1 - 2.5e-52 176.7 1.1 2.8e-52 176.5 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 XP_668631.1 - 0.00019 21.5 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 XP_668631.1 - 0.00026 21.3 0.0 0.00038 20.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 XP_668631.1 - 0.00095 19.8 3.2 0.0012 19.4 3.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 XP_668631.1 - 0.035 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 XP_668631.1 - 0.057 13.5 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MTH865 PF07747.11 XP_668632.1 - 0.0078 16.0 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 MTH865-like family RNA_pol_L_2 PF13656.6 XP_668633.1 - 7.6e-16 57.7 0.4 1.2e-15 57.0 0.4 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.22 XP_668634.1 - 3.5e-18 65.1 0.2 4.8e-18 64.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 XP_668634.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DEAD PF00270.29 XP_668635.1 - 1.6e-44 151.8 0.1 2.6e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668635.1 - 2e-28 99.0 0.2 1.3e-27 96.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668635.1 - 2.8e-06 27.4 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 XP_668635.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S3Ae PF01015.18 XP_668637.1 - 7e-88 293.5 1.4 8.5e-88 293.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 XP_668637.1 - 0.023 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SUI1 PF01253.22 XP_668637.1 - 0.68 10.5 4.5 7 7.3 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor SUI1 Cullin PF00888.22 XP_668638.1 - 1.2e-114 384.2 26.6 1.6e-114 383.8 26.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 XP_668638.1 - 2.4e-13 49.9 2.2 2.4e-13 49.9 2.2 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain SRI PF08236.11 XP_668638.1 - 0.0079 16.3 2.3 0.038 14.2 0.1 3.1 2 1 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.32 XP_668639.1 - 1.1e-25 89.4 18.1 5.2e-05 23.9 0.7 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 XP_668639.1 - 3.8e-09 36.7 0.1 0.011 16.0 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 XP_668639.1 - 0.065 11.9 2.0 1.1 7.8 0.1 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 XP_668639.1 - 0.17 12.4 0.0 84 3.9 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain eIF-6 PF01912.18 XP_668640.1 - 4.2e-77 258.0 1.7 4.2e-77 258.0 1.7 1.4 2 0 0 2 2 2 1 eIF-6 family Alg6_Alg8 PF03155.15 XP_668641.1 - 3.8e-92 309.8 36.3 8.6e-92 308.6 36.3 1.5 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family EpsG PF14897.6 XP_668641.1 - 0.66 9.2 53.0 0.13 11.5 29.4 2.2 1 1 1 2 2 2 0 EpsG family TPT PF03151.16 XP_668642.1 - 1.1e-24 87.3 12.1 1.1e-24 87.3 12.1 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 XP_668642.1 - 4.7e-08 33.3 27.0 0.00014 22.0 9.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 XP_668642.1 - 5e-05 22.7 11.8 0.0027 17.0 11.8 2.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 XP_668642.1 - 0.0025 17.4 8.6 0.011 15.2 0.6 2.5 3 0 0 3 3 3 2 Solute carrier family 35 TMEM234 PF10639.9 XP_668642.1 - 0.02 14.9 1.6 0.02 14.9 1.6 2.1 2 0 0 2 2 2 0 Putative transmembrane family 234 Guanylate_cyc PF00211.20 XP_668643.1 - 1e-16 61.1 0.0 3.5e-08 33.3 0.0 3.2 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain EB PF01683.18 XP_668644.1 - 0.00016 21.9 42.7 0.25 11.7 1.2 10.7 6 4 2 8 8 8 3 EB module FOG_N PF15888.5 XP_668644.1 - 0.0014 19.0 39.6 1.1 9.7 0.1 10.9 3 3 9 13 13 13 4 Folded gastrulation N-terminus Prok-E2_C PF14459.6 XP_668644.1 - 0.38 10.9 4.6 3.2 7.9 0.0 4.2 1 1 3 5 5 5 0 Prokaryotic E2 family C Antistasin PF02822.14 XP_668644.1 - 8.2 7.2 64.4 16 6.2 0.7 14.5 9 5 4 13 13 13 0 Antistasin family Ribosomal_S27 PF01599.19 XP_668645.1 - 7.5e-24 83.6 2.0 7.5e-24 83.6 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 XP_668645.1 - 7.1e-07 28.9 0.0 1.8e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family IBR PF01485.21 XP_668645.1 - 0.052 13.8 0.3 0.088 13.0 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Fer2_3 PF13085.6 XP_668645.1 - 0.055 13.5 0.6 0.12 12.4 0.6 1.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-C2H2_3 PF13878.6 XP_668645.1 - 0.072 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO PB1 PF00564.24 XP_668645.1 - 0.11 12.5 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 PB1 domain FAM176 PF14851.6 XP_668646.1 - 0.0036 17.0 1.0 0.0086 15.7 1.0 1.7 1 1 0 1 1 1 1 FAM176 family Herpes_glycop PF01528.16 XP_668646.1 - 0.033 13.0 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PROL5-SMR PF15621.6 XP_668646.1 - 0.035 14.6 0.0 0.07 13.7 0.0 1.7 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Polysacc_synt PF01943.17 XP_668646.1 - 0.038 13.4 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RIC3 PF15361.6 XP_668646.1 - 0.053 13.9 0.2 0.053 13.9 0.2 2.1 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Shisa PF13908.6 XP_668646.1 - 0.12 12.6 5.1 0.21 11.8 5.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Hid1 PF12722.7 XP_668646.1 - 0.14 10.3 6.4 0.14 10.2 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 XP_668646.1 - 0.28 9.9 7.3 0.34 9.6 7.3 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 XP_668646.1 - 0.43 8.9 1.4 0.49 8.8 1.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OAD_gamma PF04277.13 XP_668646.1 - 0.83 10.3 7.3 8.2 7.1 7.3 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Kei1 PF08552.11 XP_668646.1 - 1.4 8.7 5.7 5 7.0 5.7 1.8 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4834 PF16118.5 XP_668646.1 - 2.1 9.3 13.8 1.2e+02 3.8 13.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Mucin PF01456.17 XP_668646.1 - 4.8 7.2 18.4 6.3 6.8 18.2 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Coiled-coil_56 PF09813.9 XP_668647.1 - 4 7.6 4.7 6.9 6.8 4.7 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 Abhydrolase_2 PF02230.16 XP_668648.1 - 9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 XP_668648.1 - 0.011 15.6 0.4 0.051 13.5 0.2 2.2 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aminotran_5 PF00266.19 XP_668649.1 - 3.2e-81 273.2 0.0 3.7e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 XP_668649.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 XP_668649.1 - 0.022 14.0 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Abhydrolase_2 PF02230.16 XP_668650.1 - 4.4e-06 26.7 0.1 0.00015 21.6 0.1 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 XP_668650.1 - 0.17 11.6 0.0 0.77 9.4 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Glyco_hydro_42C PF08533.10 XP_668651.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain UXS1_N PF11803.8 XP_668652.1 - 0.0021 18.4 1.1 0.029 14.7 0.0 2.7 2 1 0 2 2 2 1 UDP-glucuronate decarboxylase N-terminal Tropomyosin PF00261.20 XP_668652.1 - 0.0021 17.5 11.3 0.0041 16.5 11.3 1.5 1 1 0 1 1 1 1 Tropomyosin BLOC1_2 PF10046.9 XP_668652.1 - 0.0043 17.3 1.3 0.0043 17.3 1.3 3.8 2 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 XP_668652.1 - 0.011 16.4 4.8 0.16 12.6 1.1 3.1 3 1 0 3 3 3 0 SlyX Atg14 PF10186.9 XP_668652.1 - 0.078 12.0 10.2 0.11 11.6 9.5 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 XP_668652.1 - 0.086 13.3 14.2 0.2 12.2 8.9 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Imm44 PF15571.6 XP_668652.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.3 1 1 3 4 4 4 0 Immunity protein 44 ATG16 PF08614.11 XP_668652.1 - 0.2 11.9 8.0 0.16 12.1 5.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 XP_668652.1 - 0.32 11.4 6.8 4 7.9 0.3 3.8 2 1 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 XP_668652.1 - 0.47 10.6 20.6 0.61 10.3 7.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ING PF12998.7 XP_668652.1 - 0.48 11.0 12.0 0.099 13.2 5.9 2.6 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Fzo_mitofusin PF04799.13 XP_668652.1 - 0.64 9.6 9.7 0.92 9.0 2.0 3.0 2 1 0 3 3 3 0 fzo-like conserved region Noelin-1 PF12308.8 XP_668652.1 - 0.73 9.9 4.9 0.32 11.0 0.8 2.5 2 1 0 3 3 3 0 Neurogenesis glycoprotein DUF1664 PF07889.12 XP_668652.1 - 1 9.4 10.0 1.3 9.0 4.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 XP_668652.1 - 1.4 9.3 9.2 6.2 7.2 3.2 3.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 XP_668652.1 - 2.9 8.2 8.1 50 4.2 8.1 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 XP_668652.1 - 7 7.0 13.4 14 6.1 3.8 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 XP_668652.1 - 7 6.7 13.1 1.4 9.0 3.1 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF745 PF05335.13 XP_668652.1 - 7.1 6.3 9.8 2 8.1 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) RestrictionSfiI PF11487.8 XP_668653.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme SfiI DEAD PF00270.29 XP_668654.1 - 1.1e-49 168.6 0.0 1.8e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 XP_668654.1 - 1.5e-32 112.3 0.0 7e-32 110.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 XP_668654.1 - 0.041 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 XP_668654.1 - 0.14 12.4 0.1 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Tti2 PF10521.9 XP_668654.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Tti2 family ALG11_N PF15924.5 XP_668655.1 - 7.6e-37 127.4 4.3 4.2e-36 125.0 0.9 2.7 2 1 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 XP_668655.1 - 1.4e-12 47.5 0.0 3.2e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Phage_min_cap2 PF06152.11 XP_668655.1 - 0.011 14.7 0.2 0.019 13.9 0.2 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 PP2C_C PF07830.13 XP_668655.1 - 0.36 11.3 2.3 7.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CRAL_TRIO_2 PF13716.6 XP_668656.1 - 1.9e-25 89.7 0.6 1.9e-25 89.7 0.6 2.2 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 XP_668656.1 - 8.5e-19 67.9 0.1 8.5e-19 67.9 0.1 2.2 3 0 0 3 3 3 1 RhoGAP domain DUF1708 PF08101.11 XP_668656.1 - 0.003 16.8 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF4746 PF15928.5 XP_668656.1 - 0.013 15.0 7.3 0.02 14.3 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3730 PF12530.8 XP_668656.1 - 0.013 15.0 0.2 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) UPF0565 PF10561.9 XP_668656.1 - 0.015 14.5 0.3 0.024 13.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF1682 PF07946.14 XP_668656.1 - 0.023 13.9 1.5 0.038 13.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) APOBEC_N PF08210.11 XP_668656.1 - 0.052 13.4 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 XP_668656.1 - 0.059 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 XP_668656.1 - 0.11 12.6 0.7 0.31 11.2 0.7 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CENP-T_N PF16171.5 XP_668656.1 - 0.19 10.6 1.1 0.25 10.2 1.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DUF4820 PF16091.5 XP_668656.1 - 0.24 10.7 2.5 0.4 10.0 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 XP_668656.1 - 0.55 8.5 7.2 0.97 7.6 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 XP_668656.1 - 1.3 8.1 5.9 1.8 7.6 5.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FYDLN_acid PF09538.10 XP_668656.1 - 1.5 9.5 11.4 2.3 8.9 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Prp18 PF02840.15 XP_668657.1 - 0.23 11.5 1.9 0.31 11.1 0.1 2.1 2 0 0 2 2 2 0 Prp18 domain ERCC4 PF02732.15 XP_668658.1 - 2e-14 54.1 0.9 6.5e-14 52.4 0.2 1.9 2 0 0 2 2 2 1 ERCC4 domain AP2 PF00847.20 XP_668659.1 - 3.3e-06 27.2 4.0 1e-05 25.6 0.5 2.6 1 1 1 2 2 2 1 AP2 domain Ribosomal_S30 PF04758.14 XP_668659.1 - 0.081 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S30 Fis1_TPR_C PF14853.6 XP_668660.1 - 6.7e-09 35.7 4.7 0.00018 21.5 1.0 2.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 XP_668660.1 - 9.3e-08 31.6 5.4 0.00012 21.9 0.6 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 XP_668660.1 - 1.5e-06 27.8 11.9 0.00064 19.4 1.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 XP_668660.1 - 2.9e-05 24.2 4.7 4.1e-05 23.7 4.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 XP_668660.1 - 0.00018 22.0 0.2 0.00036 21.0 0.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 XP_668660.1 - 0.0035 17.4 0.5 0.43 10.6 0.1 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 XP_668660.1 - 0.008 16.4 0.9 0.038 14.3 1.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 XP_668660.1 - 0.0096 16.1 0.6 0.0096 16.1 0.6 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3973 PF13119.6 XP_668660.1 - 0.058 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Caud_tail_N PF16838.5 XP_668660.1 - 0.077 13.4 0.3 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Caudoviral major tail protein N-terminus TPR_7 PF13176.6 XP_668660.1 - 0.078 13.1 0.1 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps52 PF04129.12 XP_668661.1 - 3.1e-07 29.5 24.8 7.1e-06 25.0 24.8 2.2 1 1 0 1 1 1 1 Vps52 / Sac2 family Mononeg_mRNAcap PF14318.6 XP_668661.1 - 0.61 9.3 2.8 0.76 9.0 0.5 2.1 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V DUF1040 PF06288.13 XP_668661.1 - 2.2 8.7 6.0 1.1 9.7 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1040) DUF2153 PF09921.9 XP_668663.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) CK_II_beta PF01214.18 XP_668664.1 - 5.5e-61 205.6 0.0 8.8e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Tmemb_9 PF05434.11 XP_668664.1 - 0.63 9.9 3.5 0.37 10.7 0.2 1.9 2 0 0 2 2 2 0 TMEM9 EGF_CA PF07645.15 XP_668665.1 - 1.3e-56 188.5 134.4 3.7e-10 39.8 9.2 10.0 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.7 XP_668665.1 - 3.4e-51 170.7 57.0 4e-09 36.2 0.6 9.0 8 0 0 8 8 8 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 XP_668665.1 - 1.5e-29 102.0 129.8 7.5e-08 32.5 9.2 9.4 9 0 0 9 9 9 7 Coagulation Factor Xa inhibitory site EGF PF00008.27 XP_668665.1 - 1.5e-19 70.0 117.7 5.2e-05 23.5 5.7 10.3 9 1 0 9 9 9 8 EGF-like domain EGF_3 PF12947.7 XP_668665.1 - 2.6e-08 33.9 108.4 0.0029 17.8 5.3 10.2 9 2 0 9 9 9 7 EGF domain hEGF PF12661.7 XP_668665.1 - 0.00038 21.0 100.2 0.028 15.0 2.8 11.2 10 2 0 10 10 10 6 Human growth factor-like EGF Tme5_EGF_like PF09064.10 XP_668665.1 - 0.022 14.7 5.3 0.022 14.7 5.3 8.4 8 0 0 8 8 8 0 Thrombomodulin like fifth domain, EGF-like RNA_POL_M_15KD PF02150.16 XP_668666.1 - 1.4e-07 31.3 8.3 1.4e-07 31.3 8.3 3.7 3 1 1 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 XP_668666.1 - 6.7e-07 29.1 0.5 6.7e-07 29.1 0.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 XP_668666.1 - 0.0025 17.8 8.1 0.038 14.0 1.6 2.7 2 1 0 2 2 2 2 Double zinc ribbon DUF3795 PF12675.7 XP_668666.1 - 0.023 15.1 5.6 0.41 11.1 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) A2L_zn_ribbon PF08792.10 XP_668666.1 - 0.19 11.5 0.1 0.19 11.5 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain CDH-cyt PF16010.5 XP_668666.1 - 0.32 10.7 1.6 0.84 9.3 0.1 2.0 2 0 0 2 2 2 0 Cytochrome domain of cellobiose dehydrogenase zinc_ribbon_15 PF17032.5 XP_668666.1 - 0.96 10.2 8.5 14 6.5 0.6 3.4 2 1 1 3 3 3 0 zinc-ribbon family zinc_ribbon_10 PF10058.9 XP_668666.1 - 1.9 8.3 11.9 3.6 7.4 0.2 3.7 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein RNHCP PF12647.7 XP_668666.1 - 3.5 7.7 7.7 7.2 6.7 1.0 3.1 2 2 1 3 3 3 0 RNHCP domain zf-AN1 PF01428.16 XP_668666.1 - 4.6 7.5 11.0 16 5.7 0.1 4.1 3 1 1 4 4 4 0 AN1-like Zinc finger RRM_1 PF00076.22 XP_668667.1 - 3.7e-11 42.7 0.0 4.6e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 XP_668667.1 - 0.0088 15.5 0.8 0.023 14.2 0.8 1.7 1 0 0 1 1 1 1 Lsm interaction motif DSPc PF00782.20 XP_668668.1 - 3.2e-07 30.2 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 XP_668668.1 - 0.0084 16.1 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.12 XP_668668.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 XP_668668.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IFT81_CH PF18383.1 XP_668668.1 - 0.023 15.0 0.3 19 5.6 0.0 3.7 4 0 0 4 4 4 0 Intraflagellar transport 81 calponin homology domain Acetyltransf_1 PF00583.25 XP_668669.1 - 4.3e-08 33.4 0.0 7.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 XP_668669.1 - 0.00065 20.1 0.0 0.0021 18.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 XP_668669.1 - 0.00074 19.5 0.0 0.0015 18.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 XP_668669.1 - 0.023 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4417 PF14386.6 XP_668670.1 - 0.052 13.1 0.7 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4417) PRP38 PF03371.15 XP_668671.1 - 1.7e-44 151.7 0.4 2.4e-44 151.3 0.4 1.1 1 0 0 1 1 1 1 PRP38 family SART-1 PF03343.13 XP_668671.1 - 0.034 12.7 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 SART-1 family Collar PF07484.12 XP_668671.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage Tail Collar Domain TMEM154 PF15102.6 XP_668672.1 - 0.13 12.2 3.2 0.25 11.2 0.6 2.3 2 0 0 2 2 2 0 TMEM154 protein family TCTP PF00838.17 XP_668673.1 - 1.6e-52 178.2 4.3 1.8e-52 178.0 4.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF2070 PF09843.9 XP_668673.1 - 0.0035 15.7 0.5 0.012 13.9 0.2 1.7 1 1 0 2 2 2 1 Predicted membrane protein (DUF2070) Tma16 PF11176.8 XP_668673.1 - 0.045 13.6 0.5 0.064 13.1 0.2 1.5 2 0 0 2 2 2 0 Translation machinery-associated protein 16 RadC PF04002.15 XP_668673.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 RadC-like JAB domain SAP30_Sin3_bdg PF13867.6 XP_668674.1 - 0.0014 18.9 0.7 0.0037 17.6 0.7 1.7 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Myosin_N PF02736.19 XP_668674.1 - 0.014 15.2 1.3 0.018 14.8 0.2 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Filament PF00038.21 XP_668675.1 - 0.0032 17.1 5.1 0.0037 16.9 5.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein ATG16 PF08614.11 XP_668675.1 - 0.0045 17.3 5.1 0.0062 16.8 5.1 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Perilipin PF03036.16 XP_668675.1 - 0.0086 15.1 1.4 0.0086 15.1 1.4 1.0 1 0 0 1 1 1 1 Perilipin family DUF5102 PF17104.5 XP_668675.1 - 0.01 15.9 1.7 0.011 15.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Npa1 PF11707.8 XP_668675.1 - 0.011 15.1 2.2 0.012 15.0 2.2 1.0 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal ATPase_2 PF01637.18 XP_668675.1 - 0.019 14.9 1.6 0.02 14.8 1.6 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Atg14 PF10186.9 XP_668675.1 - 0.019 14.0 6.5 0.02 14.0 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Death_2 PF14786.6 XP_668675.1 - 0.026 14.4 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 Tube Death domain DXP_synthase_N PF13292.6 XP_668675.1 - 0.029 13.6 1.7 0.71 9.0 0.1 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Gly_acyl_tr_C PF08444.10 XP_668675.1 - 0.03 14.5 0.2 0.044 14.0 0.2 1.3 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region HsdM_N PF12161.8 XP_668675.1 - 0.049 14.2 3.2 0.081 13.6 3.2 1.3 1 1 0 1 1 1 0 HsdM N-terminal domain CAAP1 PF15335.6 XP_668675.1 - 0.05 14.2 7.2 0.14 12.7 4.1 2.9 2 1 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 DUF948 PF06103.11 XP_668675.1 - 0.064 13.5 0.7 0.13 12.5 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nbl1_Borealin_N PF10444.9 XP_668675.1 - 0.078 12.6 4.0 0.62 9.7 0.7 3.3 1 1 2 3 3 3 0 Nbl1 / Borealin N terminal SAP PF02037.27 XP_668675.1 - 0.083 12.7 1.1 0.22 11.3 1.1 1.8 1 0 0 1 1 1 0 SAP domain DUF1664 PF07889.12 XP_668675.1 - 0.086 12.9 2.5 0.1 12.6 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Serine_rich PF08824.10 XP_668675.1 - 0.1 12.6 5.0 0.2 11.7 3.9 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain Vps51 PF08700.11 XP_668675.1 - 0.12 12.5 6.8 0.29 11.2 2.1 2.4 1 1 0 2 2 2 0 Vps51/Vps67 GAT PF03127.14 XP_668675.1 - 0.15 12.3 10.3 0.67 10.3 0.6 2.5 2 1 1 3 3 3 0 GAT domain Exonuc_VII_L PF02601.15 XP_668675.1 - 0.27 10.8 3.7 0.28 10.7 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 XP_668675.1 - 0.35 10.1 5.6 0.37 10.0 5.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 XP_668675.1 - 0.98 8.2 5.6 1.1 8.1 5.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Aida_N PF08910.10 XP_668675.1 - 1.2 9.6 4.8 1.6 9.2 3.9 1.6 1 1 0 2 2 2 0 Aida N-terminus AAA_23 PF13476.6 XP_668675.1 - 1.7 9.1 12.4 2.1 8.8 12.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 XP_668676.1 - 0.074 12.4 1.4 0.14 11.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AP2 PF00847.20 XP_668676.1 - 0.49 10.7 2.2 0.54 10.5 0.1 2.1 2 0 0 2 2 2 0 AP2 domain HUN PF08729.10 XP_668677.1 - 5.6e-06 26.2 4.7 5.6e-06 26.2 4.7 2.6 2 0 0 2 2 2 1 HPC2 and ubinuclein domain WD40 PF00400.32 XP_668678.1 - 2.7e-09 37.5 0.2 0.00053 20.7 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 XP_668678.1 - 0.024 13.4 0.7 0.22 10.2 0.1 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Hira PF07569.11 XP_668678.1 - 0.066 12.9 0.0 9.4 5.9 0.0 2.4 1 1 1 2 2 2 0 TUP1-like enhancer of split PA26 PF04636.13 XP_668679.1 - 0.0047 15.9 0.0 0.0051 15.8 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) PP2C PF00481.21 XP_668681.1 - 7.2e-63 212.6 0.2 7.5e-52 176.5 0.1 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C Spem1 PF15670.5 XP_668681.1 - 0.28 10.7 1.5 0.54 9.8 0.1 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 Choline_kinase PF01633.20 XP_668682.1 - 2.3e-51 174.4 2.8 3.2e-51 173.9 2.8 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 XP_668682.1 - 5.4e-07 29.8 0.0 6.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PolyA_pol PF01743.20 XP_668683.1 - 6.3e-22 78.3 0.1 3e-21 76.2 0.1 2.1 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 XP_668683.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.9 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A PH_11 PF15413.6 XP_668683.1 - 0.04 14.3 1.2 0.065 13.7 0.3 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain 2OG-FeII_Oxy_3 PF13640.6 XP_668684.1 - 6.7e-12 46.1 0.0 1.6e-11 45.0 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 XP_668684.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase zf-RING_2 PF13639.6 XP_668685.1 - 1.2e-11 44.8 5.2 2.1e-11 44.0 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 XP_668685.1 - 7e-08 32.2 6.0 1.8e-07 30.9 6.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 XP_668685.1 - 2.7e-07 30.8 9.0 6.5e-07 29.6 9.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 XP_668685.1 - 1e-05 25.5 2.5 1.7e-05 24.8 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 XP_668685.1 - 3.9e-05 23.4 4.7 7.5e-05 22.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 XP_668685.1 - 0.00012 22.0 4.1 0.00026 20.9 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 XP_668685.1 - 0.00017 21.2 2.7 0.00017 21.2 2.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 XP_668685.1 - 0.0015 18.5 4.6 0.0038 17.1 4.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 XP_668685.1 - 0.0022 18.1 4.4 0.0056 16.8 4.4 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 XP_668685.1 - 0.01 15.7 8.1 0.011 15.6 6.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 XP_668685.1 - 0.025 14.4 5.9 0.056 13.3 5.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 XP_668685.1 - 0.094 12.9 2.0 0.18 11.9 2.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 XP_668685.1 - 0.21 11.2 11.5 0.83 9.3 11.5 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type ANAPC_CDC26 PF10471.9 XP_668685.1 - 1.1 10.2 7.1 5.6 7.9 2.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 BK_channel_a PF03493.18 XP_668687.1 - 4.4e-14 52.4 0.1 5.5e-07 29.7 0.0 3.4 3 0 0 3 3 3 2 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 XP_668687.1 - 6.3e-12 45.3 9.6 6.3e-12 45.3 9.6 2.6 2 0 0 2 2 2 1 Ion channel Ribosomal_S2 PF00318.20 XP_668688.1 - 4.7e-24 84.8 2.8 2.4e-13 49.9 0.4 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Pox_A22 PF04848.13 XP_668688.1 - 0.035 14.2 0.7 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A22 protein PS_Dcarbxylase PF02666.15 XP_668689.1 - 2e-38 132.0 0.1 2.2e-38 131.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Nop PF01798.18 XP_668690.1 - 2.6e-83 279.0 0.1 3.7e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 XP_668690.1 - 6.9e-19 68.0 0.3 1.6e-18 66.8 0.3 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Myosin_head PF00063.21 XP_668691.1 - 2.9e-35 121.7 10.3 8.3e-34 116.8 2.9 3.9 3 1 0 3 3 3 1 Myosin head (motor domain) RCC1 PF00415.18 XP_668691.1 - 6.1e-28 97.2 5.2 6.3e-09 36.3 0.0 6.8 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 XP_668691.1 - 3.5e-13 48.1 34.1 4.7e-05 22.8 0.5 7.6 7 0 0 7 7 7 3 IQ calmodulin-binding motif RCC1_2 PF13540.6 XP_668691.1 - 5.1e-10 38.9 26.9 1.2e-06 28.1 0.4 7.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat CSRNP_N PF16019.5 XP_668691.1 - 0.35 10.7 1.9 0.85 9.5 0.2 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus BLOC1_2 PF10046.9 XP_668692.1 - 0.34 11.2 5.2 0.31 11.4 1.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFP_35_N PF07334.13 XP_668693.1 - 0.22 11.6 3.8 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ING PF12998.7 XP_668693.1 - 5.4 7.7 12.2 9.3 6.9 4.1 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF4094 PF13334.6 XP_668693.1 - 6.7 7.2 6.2 1.4 9.4 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) PTPLA PF04387.14 XP_668694.1 - 2.2e-49 167.3 7.8 3.3e-49 166.8 7.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SprT-like PF10263.9 XP_668695.1 - 1.6e-19 69.9 0.5 2.4e-19 69.2 0.2 1.4 2 0 0 2 2 2 1 SprT-like family Proteasome_A_N PF10584.9 XP_668696.1 - 9.9e-12 44.3 0.0 1.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Proteasome PF00227.26 XP_668696.1 - 3.2e-10 39.8 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 XP_668697.1 - 7.6e-12 45.1 0.0 8.7e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Cryptosporidium_hominis-ASM642v1/GCF_000006425.1_ASM642v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Cryptosporidium_hominis-ASM642v1/GCF_000006425.1_ASM642v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Cryptosporidium_hominis-ASM642v1/GCF_000006425.1_ASM642v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Apicomplexa/Cryptosporidium_hominis-ASM642v1/GCF_000006425.1_ASM642v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 00:29:41 2019 # [ok]