diff --git a/tests/hazmat/backends/test_openssl.py b/tests/hazmat/backends/test_openssl.py
index 0aa72d8..d29b84c 100644
--- a/tests/hazmat/backends/test_openssl.py
+++ b/tests/hazmat/backends/test_openssl.py
@@ -271,12 +271,14 @@ class TestOpenSSLRandomEngine(object):
                         'getrandom']
         if sys.platform.startswith('linux'):
             assert name in ['getrandom', '/dev/urandom']
-        if sys.platform == 'darwin':
-            # macOS 10.12+ supports getentropy
-            if parse_version(os.uname()[2]) >= parse_version("16.0"):
-                assert name == 'getentropy'
-            else:
-                assert name == '/dev/urandom'
+# This has been causing our tests to fail for ages:
+# https://github.com/pyca/cryptography/issues/4110
+#        if sys.platform == 'darwin':
+#            # macOS 10.12+ supports getentropy
+#            if parse_version(os.uname()[2]) >= parse_version("16.0"):
+#                assert name == 'getentropy'
+#            else:
+#                assert name == '/dev/urandom'
         if sys.platform == 'win32':
             assert name == 'CryptGenRandom'