GenomeFlowInterface Settings: shuffle: True pos_sampling_rate: 0.05 validation_chroms: ['chr22'] holdout_chroms: ['chr1', 'chr8', 'chr21'] optimizer: adam learning rate: 0.0003 batch size: 256 epoch size: 2500000 max num of epochs: 100 early stopping metrics: auPRC early stopping patience: 4 Epoch 1: Metrics across all datasets: Balanced Accuracy: 94.62% auROC: 0.995 auPRC: 0.346 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 22.3% Num Positives: 1135 Num Negatives: 1022650 New best auPRC. Saving model. Epoch 2: Metrics across all datasets: Balanced Accuracy: 91.73% auROC: 0.990 auPRC: 0.269 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 0.0% Num Positives: 1135 Num Negatives: 1022650 Epoch 3: Metrics across all datasets: Balanced Accuracy: 89.27% auROC: 0.990 auPRC: 0.313 Recall at 5% | 10% | 25% | 50% FDR: 0.4% | 0.4% | 0.7% | 11.7% Num Positives: 1135 Num Negatives: 1022650 Epoch 4: Metrics across all datasets: Balanced Accuracy: 86.28% auROC: 0.986 auPRC: 0.310 Recall at 5% | 10% | 25% | 50% FDR: 0.3% | 0.3% | 0.3% | 5.6% Num Positives: 1135 Num Negatives: 1022650 Epoch 5: Metrics across all datasets: Balanced Accuracy: 87.31% auROC: 0.989 auPRC: 0.325 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 0.0% | 18.8% Num Positives: 1135 Num Negatives: 1022650 Epoch 6: Metrics across all datasets: Balanced Accuracy: 84.11% auROC: 0.991 auPRC: 0.319 Recall at 5% | 10% | 25% | 50% FDR: 0.4% | 0.4% | 0.5% | 15.3% Num Positives: 1135 Num Negatives: 1022650 Finished training after 6 epochs. The best model's architecture and weights (from epoch 1) were saved to /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-DNAse-Duke-cuts-SP1/model.arch.json and /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-DNAse-Duke-cuts-SP1/model.weights.h5