GenomeFlowInterface Settings: shuffle: True pos_sampling_rate: 0.05 validation_chroms: ['chr22'] holdout_chroms: ['chr1', 'chr8', 'chr21'] optimizer: adam learning rate: 0.0003 batch size: 256 epoch size: 2500000 max num of epochs: 100 early stopping metrics: auPRC early stopping patience: 4 Epoch 1: Metrics across all datasets: Balanced Accuracy: 87.40% auROC: 0.990 auPRC: 0.472 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 20.1% | 49.8% Num Positives: 2727 Num Negatives: 995354 New best auPRC. Saving model. Epoch 2: Metrics across all datasets: Balanced Accuracy: 91.97% auROC: 0.990 auPRC: 0.516 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 28.7% | 55.8% Num Positives: 2727 Num Negatives: 995354 New best auPRC. Saving model. Epoch 3: Metrics across all datasets: Balanced Accuracy: 87.02% auROC: 0.987 auPRC: 0.493 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 24.2% | 53.3% Num Positives: 2727 Num Negatives: 995354 Epoch 4: Metrics across all datasets: Balanced Accuracy: 87.50% auROC: 0.984 auPRC: 0.475 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 16.2% | 52.3% Num Positives: 2727 Num Negatives: 995354 Epoch 5: Metrics across all datasets: Balanced Accuracy: 86.70% auROC: 0.984 auPRC: 0.487 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 24.6% | 52.7% Num Positives: 2727 Num Negatives: 995354 Epoch 6: Metrics across all datasets: Balanced Accuracy: 85.70% auROC: 0.984 auPRC: 0.485 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 25.2% | 51.0% Num Positives: 2727 Num Negatives: 995354 Epoch 7: Metrics across all datasets: Balanced Accuracy: 84.72% auROC: 0.979 auPRC: 0.476 Recall at 5% | 10% | 25% | 50% FDR: 0.1% | 0.1% | 23.9% | 50.5% Num Positives: 2727 Num Negatives: 995354 Finished training after 7 epochs. The best model's architecture and weights (from epoch 2) were saved to /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-USF1/model.arch.json and /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-USF1/model.weights.h5