GenomeFlowInterface Settings: shuffle: True pos_sampling_rate: 0.05 validation_chroms: ['chr22'] holdout_chroms: ['chr1', 'chr8', 'chr21'] optimizer: adam learning rate: 0.0003 batch size: 256 epoch size: 2500000 max num of epochs: 100 early stopping metrics: auPRC early stopping patience: 4 Epoch 1: Metrics across all datasets: Balanced Accuracy: 86.54% auROC: 0.984 auPRC: 0.484 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 21.5% | 49.9% Num Positives: 5476 Num Negatives: 968578 New best auPRC. Saving model. Epoch 2: Metrics across all datasets: Balanced Accuracy: 85.19% auROC: 0.985 auPRC: 0.499 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 6.3% | 22.7% | 51.1% Num Positives: 5476 Num Negatives: 968578 New best auPRC. Saving model. Epoch 3: Metrics across all datasets: Balanced Accuracy: 88.96% auROC: 0.984 auPRC: 0.502 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 3.9% | 22.8% | 52.4% Num Positives: 5476 Num Negatives: 968578 New best auPRC. Saving model. Epoch 4: Metrics across all datasets: Balanced Accuracy: 85.59% auROC: 0.983 auPRC: 0.507 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 3.5% | 24.3% | 53.3% Num Positives: 5476 Num Negatives: 968578 New best auPRC. Saving model. Epoch 5: Metrics across all datasets: Balanced Accuracy: 85.83% auROC: 0.982 auPRC: 0.501 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 5.5% | 24.4% | 52.9% Num Positives: 5476 Num Negatives: 968578 Epoch 6: Metrics across all datasets: Balanced Accuracy: 85.23% auROC: 0.980 auPRC: 0.496 Recall at 5% | 10% | 25% | 50% FDR: 0.2% | 5.5% | 23.1% | 51.4% Num Positives: 5476 Num Negatives: 968578 Epoch 7: Metrics across all datasets: Balanced Accuracy: 85.66% auROC: 0.979 auPRC: 0.487 Recall at 5% | 10% | 25% | 50% FDR: 0.0% | 0.0% | 23.3% | 50.6% Num Positives: 5476 Num Negatives: 968578 Epoch 8: Metrics across all datasets: Balanced Accuracy: 84.02% auROC: 0.977 auPRC: 0.487 Recall at 5% | 10% | 25% | 50% FDR: 0.9% | 5.5% | 22.5% | 50.1% Num Positives: 5476 Num Negatives: 968578 Epoch 9: Metrics across all datasets: Balanced Accuracy: 83.96% auROC: 0.976 auPRC: 0.485 Recall at 5% | 10% | 25% | 50% FDR: 0.7% | 7.2% | 20.1% | 50.8% Num Positives: 5476 Num Negatives: 968578 Finished training after 9 epochs. The best model's architecture and weights (from epoch 4) were saved to /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-E2F6/model.arch.json and /users/marinovg/2018-01-25-histone-mods/tfdragonn-SequenceAndDnaseClassifier-K562-ATAC-E2F6/model.weights.h5