# species: Homo sapiens # support: EXP, IMP, ISS, ISM, TAS, IEA, HMP, HEP, IDA, IGI, ISO, IGC, NAS, HGI, IPI, IEP, ISA, RCA, IC, HDA # associations retrieved on: 2019-10-08 13:21:20-04 # gofunc built on: 2018-02-21 10:04:34.764444-05 # gene associations file: ftp://ftp.geneontology.org/pub/go/gene-associations/goa_human.gaf.gz # revision: 2018-02-02 $ # downloaded on: 2018-02-14 09:47:26-05 # GO DAG files from: http://archive.geneontology.org/latest-full/go_201512-termdb-tables.tar.gz # downloaded on: 2015-12-22 05:43:21-05 # translation required: yes # translation info: # authority: ensembl # synergizer db built on: 2015-11-17 14:24:21.26681-05 # synergizer db built from: Ensembl Genes 82 / Metazoa Mart / Plant Mart # namespace: hgnc_symbol # coverage: 99.8% # size of "genespace": 18224 # number of attributes: 20270 # NOTE: the last record consists of all the entities in the # "genespace" that are not associated with any attribute (for # the requested support). # Original number of entities in query: 2841 # Number of entities in query: 2841 # Total number of entities: 18691 # Original total number of entities: 18224 # Entities not in default gene space: 467 # Total number of attributes: 20270 # Translation required: yes # Translation coverage: 0.997782 # Mode: unordered # Number of simulations: 1000 # Adjusted P-value cutoff: 0.05 # Over/under: over # Evidence codes: EXP, IMP, ISS, ISM, TAS, IEA, HMP, HEP, IDA, IGI, ISO, IGC, NAS, HGI, IPI, IEP, ISA, RCA, IC, HDA OVERREPRESENTED ATTRIBUTES N X LOD P P_adj attrib ID attrib name 9 11 1.32760184226605 1.756693959678e-06 0.007 GO:0017154 semaphorin receptor activity 14 24 0.888544975395124 1.46866126195056e-06 0.006 GO:0071526 semaphorin-plexin signaling pathway 13 24 0.817821213311609 1.07263784211256e-05 0.029 GO:0035924 cellular response to vascular endothelial growth factor stimulus 18 38 0.704124707370556 2.77134433416088e-06 0.009 GO:0004407 histone deacetylase activity 18 40 0.663641178779842 6.89025709961645e-06 0.023 GO:0033558 protein deacetylase activity 21 52 0.582994554887909 9.77678044497187e-06 0.027 GO:0019213 deacetylase activity 29 72 0.581103418389363 2.24428456290403e-07 <0.001 GO:0005089 Rho guanyl-nucleotide exchange factor activity 30 80 0.530741203615932 8.70237577336414e-07 0.003 GO:0043535 regulation of blood vessel endothelial cell migration 27 77 0.48531089294861 1.29837908624223e-05 0.044 GO:0008013 beta-catenin binding 40 117 0.468690764027175 2.60384474208578e-07 <0.001 GO:0035023 regulation of Rho protein signal transduction 43 129 0.45222803910426 2.12194371569395e-07 <0.001 GO:0051015 actin filament binding 31 94 0.445066602432055 1.28503207166252e-05 0.039 GO:0060560 developmental growth involved in morphogenesis 43 132 0.437338456717246 4.36527027372922e-07 0.002 GO:0031589 cell-substrate adhesion 57 191 0.382554174998892 1.93157895466292e-07 <0.001 GO:0046578 regulation of Ras protein signal transduction 41 138 0.379184961297551 1.07558311237245e-05 0.029 GO:0010594 regulation of endothelial cell migration 70 245 0.356418515636414 5.70643431842649e-08 <0.001 GO:0030036 actin cytoskeleton organization 100 352 0.354999266344214 1.25200701004418e-10 <0.001 GO:0003779 actin binding 81 289 0.345369961603602 1.38202162333194e-08 <0.001 GO:0051056 regulation of small GTPase mediated signal transduction 54 195 0.336587548949639 5.02653075118213e-06 0.019 GO:0010632 regulation of epithelial cell migration 83 302 0.333579617564073 2.42954848602832e-08 <0.001 GO:0030029 actin filament-based process 60 220 0.327638056850799 2.64983548106135e-06 0.009 GO:0031267 small GTPase binding 67 248 0.32229755304243 1.02842529445547e-06 0.004 GO:0001525 angiogenesis 67 258 0.298728156513984 4.55140747605123e-06 0.015 GO:0045765 regulation of angiogenesis 72 280 0.293136741428074 2.99895330205166e-06 0.011 GO:1901342 regulation of vasculature development 64 250 0.290143347937288 1.20857797051223e-05 0.03 GO:0051020 GTPase binding 73 292 0.276608941610473 7.58583711625613e-06 0.023 GO:0005085 guanyl-nucleotide exchange factor activity 91 378 0.255478865771003 3.3643825814826e-06 0.011 GO:0005911 cell-cell junction 102 432 0.24478680494212 2.25764932045814e-06 0.008 GO:0050839 cell adhesion molecule binding 93 400 0.235419566983284 1.20446513092826e-05 0.03 GO:0043087 regulation of GTPase activity 155 690 0.218915252930826 1.73744334901011e-07 <0.001 GO:0005856 cytoskeleton 174 782 0.214486624326565 6.07167967312576e-08 <0.001 GO:0008092 cytoskeletal protein binding 109 488 0.213174589982342 1.4990576507359e-05 0.047 GO:0070161 anchoring junction 154 703 0.204346320698649 9.44408941990789e-07 0.004 GO:0048646 anatomical structure formation involved in morphogenesis 233 1164 0.15646745339963 2.97037411948706e-06 0.011 GO:0006928 movement of cell or subcellular component 284 1428 0.155160158615297 4.08679726081569e-07 0.002 GO:0005524 ATP binding 288 1463 0.149380228593077 8.47191865386591e-07 0.003 GO:0032559 adenyl ribonucleotide binding 288 1471 0.146197789923459 1.37061271284205e-06 0.006 GO:0030554 adenyl nucleotide binding