# GREAT version 4.0.4 Species assembly: hg19 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage coiled cecum 3 5.098583e-9 0.000015548978622333334 10.14335 12 0.008 257 0.031836312848249025 10.37416 3 3 0.001677852 abnormal Leydig cell differentiation 4 5.617732e-9 0.000012849157517 5.454111 19 0.01266667 243 0.028161307233744857 5.763423 5 9 0.002796421 sex reversal 20 0.000001467117 0.00067113267165 3.94766 18 0.012 124 0.0034288732873387095 5.187081 8 16 0.004474273 abnormal sulcus ampullaris morphology 25 0.000002775878 0.00101586031288 6.171576 11 0.007333333 257 0.031836312848249025 10.37416 3 3 0.001677852 abnormal urine pH 31 0.000003888012 0.001147465218967742 4.0602 16 0.01066667 234 0.026623500073931623 3.772422 8 22 0.004474273 failure of initiation of embryo turning 37 0.000005691942 0.0014074480367027027 2.908792 24 0.016 78 0.0013406545797435897 3.458054 15 45 0.008389262 abnormal cecum morphology 45 0.00001043603 0.002121760854888889 3.412415 18 0.012 153 0.006532206607843137 4.243975 9 22 0.005033557 abnormal active avoidance behavior 58 0.00001920802 0.00302989956862069 4.247811 13 0.008666667 114 0.003139406318508772 6.051594 7 12 0.003914989 abnormal posterior semicircular canal morphology 71 0.00003617334 0.004661266023380282 2.889065 20 0.01333333 158 0.007668923420253164 4.610738 8 18 0.004474273 small cecum 81 0.00004087621 0.004616993151728395 6.558447 8 0.005333333 144 0.005468665443402778 10.37416 4 4 0.002237136 abnormal spongiotrophoblast layer morphology 85 0.00005024564 0.005408204239529412 2.533234 24 0.016 307 0.041817545889250816 2.420638 14 60 0.007829978 abnormal external female genitalia morphology 110 0.0001041231 0.00866020219909091 2.752174 19 0.01266667 102 0.0022769277752941173 5.532886 8 15 0.004474273 decreased palatal length 121 0.0001299938 0.009829035340495866 5.538303 8 0.005333333 257 0.031836312848249025 10.37416 3 3 0.001677852 abnormal superior semicircular canal morphology 132 0.0001801012 0.012482923324242423 2.816644 17 0.01133333 182 0.012307762626923078 4.841275 7 15 0.003914989 abnormal liver development 147 0.000213313 0.013276194809523809 2.210882 26 0.01733333 324 0.045349559888888884 2.59354 12 48 0.006711409 vasculature congestion 168 0.0002892357 0.015751294162500002 2.130216 27 0.018 217 0.019161071125806454 2.689597 14 54 0.007829978 abnormal serotonin level 190 0.0003661969 0.017633344411052628 2.035161 29 0.01933333 333 0.04845796698198197 2.288418 15 68 0.008389262 abnormal lateral semicircular canal morphology 195 0.0003743137 0.017562030981025642 2.354171 21 0.014 119 0.00339008353 4.668372 9 20 0.005033557 visceral vascular congestion 200 0.0004162085 0.0190394578325 2.281821 22 0.01466667 326 0.04625159079447853 2.881711 10 36 0.005592841 abnormal CD4-negative NK T cell number 206 0.0004526326 0.02010260027864078 4.104184 9 0.006 160 0.008415141555625 7.410115 5 7 0.002796421