# GREAT version 4.0.4 Species assembly: hg19 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage head bobbing 4 6.677823e-9 0.00001527385065675 3.092997 36 0.024 85 0.005371585636117647 3.668227 12 37 0.007317073 abnormal neocortex morphology 6 9.159039e-9 0.0000139660079685 3.398383 31 0.02066667 69 0.0037097935355072465 4.147134 11 30 0.006707317 abnormal head movements 8 2.074131e-8 0.00002372028064875 2.362505 53 0.03533333 60 0.0025532099051666667 2.730088 21 87 0.01280488 decreased circulating LDL cholesterol level 19 2.247049e-7 0.0001082013226368421 2.873812 32 0.02133333 46 0.0006677332015869565 3.207417 19 67 0.01158537 decreased aggression towards mice 32 0.000001623306 0.0004641133310625 3.050681 25 0.01666667 101 0.010724412507920791 3.900126 10 29 0.006097561 abnormal sulcus ampullaris morphology 38 0.000002775878 0.0006683291532105264 6.171576 11 0.007333333 176 0.035867937135227276 11.31037 3 3 0.001829268 abnormal parietal lobe morphology 50 0.000009288459 0.0016996022278200002 2.525791 29 0.01933333 101 0.010724412507920791 3.900126 10 29 0.006097561 abnormal somatosensory cortex morphology 77 0.00004497968 0.005344403796363637 2.443303 26 0.01733333 202 0.04565070189108911 3.619317 8 25 0.004878049 abnormal superior semicircular canal morphology 86 0.00005851847 0.006225412581744185 2.982329 18 0.012 106 0.01224395133962264 5.278171 7 15 0.004268293 impaired swimming 94 0.00007636609 0.007432695291595745 2.113139 33 0.022 193 0.04080580095025907 2.458775 15 69 0.009146341 abnormal posterior semicircular canal morphology 105 0.0001078063 0.009393522273333333 2.744611 19 0.01266667 90 0.007269827929777779 5.026829 8 18 0.004878049 decreased circulating testosterone level 137 0.0002287215 0.0152742555 2.333872 23 0.01533333 190 0.03919452787157894 2.962239 11 42 0.006707317 tonic seizures 141 0.0002837613 0.01841228463617021 2.808392 16 0.01066667 182 0.037321023061538464 3.770122 8 24 0.004878049 increased mean systemic arterial blood pressure 150 0.0003190816 0.019461850389333336 2.445086 20 0.01333333 146 0.025562017743835614 3.190103 11 39 0.006707317 dilated endolymphatic duct 156 0.0003528159 0.020691747878846155 3.576085 11 0.007333333 198 0.04279316294343435 5.655183 5 10 0.00304878 decreased circulating alanine transaminase level 192 0.000767254 0.036560452322916666 2.058121 25 0.01666667 181 0.0369168822198895 2.412878 16 75 0.009756098 abnormal resting posture 196 0.0008084511 0.037737342417857145 3.229028 11 0.007333333 121 0.018104237790082647 7.068979 5 8 0.00304878