# GREAT version 4.0.4 Species assembly: hg19 Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included # Term Name Binom Rank Binom Raw P-Value Binom FDR Q-Val Binom Fold Enrichment Binom Observed Region Hits Binom Region Set Coverage Hyper Rank Hyper FDR Q-Val Hyper Fold Enrichment Hyper Observed Gene Hits Hyper Total Genes Hyper Gene Set Coverage decreased corpus callosum size 14 1.129613e-7 0.00007382020955 3.17547 29 0.01611111 351 0.03486225146723647 2.914539 10 31 0.004870921 thin myocardium 18 3.090729e-7 0.00015709488678333333 2.426177 42 0.02333333 113 0.002033652674336283 2.548353 22 78 0.01071603 coiled cecum 30 0.000002493217 0.0007603480777666667 7.04399 10 0.005555556 355 0.0348968374112676 9.035071 3 3 0.001461276 abnormal seminiferous tubule epithelium morphology 35 0.000003537355 0.0009246645970000001 2.175092 43 0.02388889 375 0.03614184364 2.030353 20 89 0.009741841 centrally nucleated skeletal muscle fibers 38 0.000005095196 0.0012267354790526316 2.361261 35 0.01944444 142 0.004172019382605635 2.601005 19 66 0.009254749 heart left ventricle hypertrophy 45 0.00001328865 0.0027017301966666667 2.393431 31 0.01722222 327 0.02937438933333333 2.37765 15 57 0.007306381 hydrops fetalis 53 0.00002854122 0.004926860788301886 2.027848 41 0.02277778 334 0.030983061107784426 2.168417 18 75 0.008767657 decreased skeletal muscle fiber size 67 0.0000616315 0.00841591930597015 2.139867 33 0.01833333 253 0.01755851851422925 2.258768 19 76 0.009254749 abnormal embryonic/fetal subventricular zone morphology 73 0.00006958557 0.008721073697671234 2.33441 27 0.015 351 0.03486225146723647 2.914539 10 31 0.004870921 abnormal fear-related response 75 0.00007285673 0.008887549636933334 2.021013 37 0.02055556 102 0.0012852192294117647 3.071924 17 50 0.008280565 decreased growth hormone level 81 0.00009044527 0.010215849076913579 2.555394 22 0.01222222 139 0.004033237919784174 3.497447 12 31 0.005845105 abnormal parietal lobe morphology 83 0.00009644538 0.01063106965807229 2.177406 30 0.01666667 85 0.00047433076608235296 4.050204 13 29 0.006332197 abnormal cochlear inner hair cell number 119 0.0002344328 0.018023745270588237 2.442577 21 0.01166667 195 0.008610743216923077 3.614028 10 25 0.004870921 abnormal optokinetic reflex 126 0.0002822494 0.020494442544444446 3.983801 10 0.005555556 286 0.021823819867132867 7.228057 4 5 0.001948368 abnormal somatosensory cortex morphology 135 0.000327494 0.022194389674074073 2.114396 27 0.015 119 0.002320574655882353 3.975431 11 25 0.005358013 impaired fibroblast cell migration 161 0.0006287973 0.03573209004782609 3.588331 10 0.005555556 174 0.005990617974712643 6.02338 6 9 0.002922552 abnormal incus morphology 164 0.0006451377 0.035990029373780485 2.370035 19 0.01055556 249 0.01725575253373494 3.535462 9 23 0.004383829 abnormal fetal cardiomyocyte morphology 168 0.0006845724 0.03728067195 2.585635 16 0.008888889 209 0.011766655847846889 3.475027 10 26 0.004870921 frontal bone foramen 176 0.0007725133 0.040157523759659086 4.810323 7 0.003888889 355 0.0348968374112676 9.035071 3 3 0.001461276 gonadal ridge hypoplasia 180 0.0008434522 0.04287080098777778 4.164279 8 0.004444444 355 0.0348968374112676 9.035071 3 3 0.001461276