******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.12.0 (Release date: Tue Jun 27 16:22:50 2017 -0700) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme-suite.org . This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme-suite.org . ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZSCAN5A.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr14:55051525-55052025 1.0000 100 chr21:41766760-41767260 1.0000 100 chr5:139517786-139518286 1.0000 100 chr9:132354595-132355095 1.0000 100 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chr6:143511305-143511805 1.0000 100 chr12:124914536-12491503 1.0000 100 chr16:30698064-30698564 1.0000 100 chr19:4576108-4576608 1.0000 100 chr17:59209674-59210174 1.0000 100 chr14:35826360-35826860 1.0000 100 chr17:82065643-82066143 1.0000 100 chr13:52194223-52194723 1.0000 100 chr5:111092027-111092527 1.0000 100 chr12:51025917-51026417 1.0000 100 chr19:35947355-35947855 1.0000 100 chr8:94719608-94720108 1.0000 100 chr16:30874993-30875493 1.0000 100 chr17:75012362-75012862 1.0000 100 chr1:99969664-99970164 1.0000 100 chr17:18780966-18781466 1.0000 100 chr21:32612315-32612815 1.0000 100 chr1:234723978-234724478 1.0000 100 chr19:41310158-41310658 1.0000 100 chr9:137240417-137240917 1.0000 100 chr19:36054120-36054620 1.0000 100 chr21:45075070-45075570 1.0000 100 chr12:106357535-10635803 1.0000 100 chr17:748648-749148 1.0000 100 chr17:32341949-32342449 1.0000 100 chr15:64387543-64388043 1.0000 100 chr1:26695404-26695904 1.0000 100 chr6:131628016-131628516 1.0000 100 chr20:33401276-33401776 1.0000 100 chr1:93078947-93079447 1.0000 100 chr21:39183023-39183523 1.0000 100 chr7:102572329-102572829 1.0000 100 chr6:143450521-143451021 1.0000 100 chr10:63520786-63521286 1.0000 100 chr1:16644502-16645002 1.0000 100 chr2:11743847-11744347 1.0000 100 chr2:223957184-223957684 1.0000 100 chr10:133394063-13339456 1.0000 100 chr19:35643422-35643922 1.0000 100 chr16:25258014-25258514 1.0000 100 chr6:157323318-157323818 1.0000 100 chr15:89893835-89894335 1.0000 100 chr8:27948380-27948880 1.0000 100 chr1:44213172-44213672 1.0000 100 chr2:241102113-241102613 1.0000 100 chr2:232550400-232550900 1.0000 100 chr5:176388756-176389256 1.0000 100 chr10:17201431-17201931 1.0000 100 chr19:35545251-35545751 1.0000 100 chr19:37655848-37656348 1.0000 100 chr20:45972075-45972575 1.0000 100 chr1:63523112-63523612 1.0000 100 chr1:1374997-1375497 1.0000 100 chr17:30906047-30906547 1.0000 100 chr1:227735043-227735543 1.0000 100 chr19:10416593-10417093 1.0000 100 chr1:37989835-37990335 1.0000 100 chr1:228082122-228082622 1.0000 100 chr21:43728515-43729015 1.0000 100 chr1:163321603-163322103 1.0000 100 chr17:78558309-78558809 1.0000 100 chr6:4775738-4776238 1.0000 100 chr15:49046311-49046811 1.0000 100 chr20:58650974-58651474 1.0000 100 chr21:32771773-32772273 1.0000 100 chr12:1198821-1199321 1.0000 100 chr7:103149221-103149721 1.0000 100 chr19:1383570-1384070 1.0000 100 chr19:1021409-1021909 1.0000 100 chr21:46635663-46636163 1.0000 100 chr1:236097028-236097528 1.0000 100 chr1:2871218-2871718 1.0000 100 chr1:40257889-40258389 1.0000 100 chr5:40835080-40835580 1.0000 100 chr1:183471821-183472321 1.0000 100 chr2:1528489-1528989 1.0000 100 chr10:93702422-93702922 1.0000 100 chrUn_KI270467v1:2903-34 1.0000 100 chr10:3314598-3315098 1.0000 100 chr3:4978473-4978973 1.0000 100 chr15:65610889-65611389 1.0000 100 chr21:39313555-39314055 1.0000 100 chrX:73944016-73944516 1.0000 100 chr1:125179939-125180439 1.0000 100 chr1:155244567-155245067 1.0000 100 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZSCAN5A.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered -oc /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZSCAN5A.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/meme_out -mod zoops -nmotifs 10 -minw 5 -maxw 50 -bfile /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZSCAN5A.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background -dna -revcomp -nostatus model: mod= zoops nmotifs= 10 evt= inf object function= E-value of product of p-values width: minw= 5 maxw= 50 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 600 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 60000 N= 600 shuffle= -1 strands: + - sample: seed= 0 ctfrac= -1 maxwords= -1 Letter frequencies in dataset: A 0.177 C 0.323 G 0.323 T 0.177 Background letter frequencies (from /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZSCAN5A.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background): A 0.180 C 0.320 G 0.320 T 0.180 ******************************************************************************** ******************************************************************************** MOTIF KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 width = 31 sites = 42 llr = 710 E-value = 6.0e-079 ******************************************************************************** -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1221::1:114:1:::22:312141111::: pos.-specific C 11:::1:::2:11::111::::::32:::11 probability G 4251626:715252715342918:4272725 matrix T 55384739172637372464:7162516364 bits 2.5 2.2 2.0 * 1.7 * Relative 1.5 * * Entropy 1.2 * * ** * (24.4 bits) 1.0 ** * * * * * **** * 0.7 *** * *** *** ****** ***** 0.5 ************ *** ****** ***** 0.2 ************************ ****** 0.0 ------------------------------- Multilevel TTGTGTGTGTGTGTGTGTTTGTGTGTGTGTG consensus GAT T T AGTGT AGGA A ACC GTGT sequence G T G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr19:36837854-36838354 - 55 4.00e-16 GCTTGTGTGT GTGTGTGTGTATGTGTGTGTGTGTGTGTGTG TGCGCGCACG chr19:35947355-35947855 + 43 1.02e-15 GGCACTGTTC gtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtgtgtgtg chr12:57111899-57112399 - 49 1.02e-15 CTGCCTGCAC GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TAGTCTTGTG chr1:156661290-156661790 + 66 1.02e-15 GGCCCAGTCC gtgtgtgtgtgtgtgtgtgtgtgtgtgtgtg tgtg chr10:101830480-10183098 - 2 8.07e-14 AGGCCTGCGT GCGTGTGTGTGTGTGTGTGTGTGTGTGTGTG G chr20:52972205-52972705 + 14 9.63e-14 gtgtgtgtgc gagggtgtgtgtgtgtgtttgtgtgtgtgtg catatgtggg chr12:112387664-11238816 - 39 1.13e-12 TGAGCCATAA CTTTTTGTTTTTGTTTTTTTGTGTTTTTGTG AGACGGAGTC chr22:37844516-37845016 + 18 6.69e-12 cacgcccagc taatttttgtatttttagtagagacggggtt tcaccatgtt chr19:39033050-39033550 - 46 6.69e-12 CACGCCCAGC TAATTTTTGTATTTTTAGTAGAGACGGGGTT TCACCATGTT chr21:45591078-45591578 - 10 2.30e-11 CCATATGGAG TGTTATGTGTATCTGTGTGTGTGTGTGTGTC CATATGGAG chr1:228782502-228783002 + 39 8.37e-11 gtgatgcctg gtgtgtgtgtgttgtttgtgatgtgtgtgcg gcatgtgtgt chr1:235078182-235078682 + 1 1.21e-10 . tatgtgttatgtgtgtatgagtatgtgtgtt gtgtgtgttg chr20:35616573-35617073 + 21 1.37e-10 catgcccggc caatttttgtgtttttagtagagacggggtt tctccgtgtt chr19:33249578-33250078 - 27 2.50e-10 GGTGTGTGCA TGTGGTGTGTATCTGTGTGTGTGTGTGATGT GTGTGTGAGG chr1:184386497-184386997 - 57 5.63e-10 GTGTGGGCAG GTGTGTGTGTGTGTGTACGTGTGTGCGCGCG CGCCCTGCAG chr5:59303215-59303715 + 4 5.31e-09 ttg tttttattgcatttgcttttgggttcttggt catgaaatcc chr21:6565296-6565796 - 20 7.17e-09 GTGGAGTGTG TGGTGTGTGTGGAGTGTGTGGAGTGTGTGGT GTGTGTGGAG chr7:139339841-139340341 + 6 7.17e-09 cccgg ctaattctgtatttttagtagagacagggtt tctctgtgtt chr5:176591624-176592124 + 19 8.72e-09 ggtgatgatg gtgttggtgttgaggtgatggtgatggttgt gatggtgatg chr5:172958980-172959480 - 31 8.72e-09 AGGCTTACTG GTGTTCTTTTTTTTTTTTTTGAGACGGAGTC TCGCTCTGTC chr8:28401253-28401753 + 1 1.28e-08 . atatgtgtgggtgcgcgagtgtgtatgtgtg tgacgcgtgt chr1:40691648-40692148 + 18 2.72e-08 TCCTGAGCAG AGGTGTGTGAGTGTGCGGGAGTTTCTGTGCG AGGGTGATAG chr4:189234913-189235413 + 22 2.98e-08 TCTGTGGTGG TGTTTGGTGTAGTTGTAGTAGTGCTCTGTGG TGGTGTTTGG chr4:189233710-189234210 + 35 2.98e-08 TCTGTGGTGG TGTTTGGTGTAGTTGTAGTAGTGCTCTGTGG TGGTGTTTGG chr21:37366816-37367316 + 55 3.90e-08 GGACCGGTGT GAGTGCGAGTGTGTGTGCGAGGGAGCGTGTG CGAGGGCGAT chr19:36851059-36851559 + 65 5.56e-08 GCTTCCGTGT GTGTGTGTGCGCGCGCGTTGGTGATATTGTT GATGG chr1:24642579-24643079 - 28 6.62e-08 GGCTTCCCTC TCGTTGTGAAAGTTGTGATTGTGTAGGTTTT ACGCGTTTAC chr17:1293386-1293886 + 5 7.22e-08 TGGG TTGAGTTTGATGATGTCGTGGGTTGTGTTTG ATGATGTCGC chr20:50165934-50166434 + 70 1.20e-07 TGCTTCTGAC TCATGCGTGCTTGGCTCTTTGTGATTATGTG chr19:36687092-36687592 - 20 1.31e-07 TAGCTCGGGC CTGTGTATGCACCTGTGCGTGTGTGTTTGAT GCCAGGACAA chr1:28373345-28373845 + 46 1.67e-07 cgcctggccC ATAAttttataatttttatagagacaggtct cgccatgttg chrUn_KI270467v1:2903-34 + 41 2.50e-07 ggtactttga tattttatgtacagtatgtaatatatatttt gagtatttgg chr19:36604662-36605162 - 69 2.50e-07 T GGCTGCGTCCGTGTGTGGTGGTGTGAGTGGG CGCGCCTGTG chr14:70359486-70359986 + 20 2.50e-07 TTTCCTTGGT TATTTGGTGCTCGGTCCTTAGTGAATGGTTT CCGCTAGGCA chr17:26603652-26604152 - 28 5.83e-07 AATGCATCTG TATAGTTTTTATGTGAAGATGATTCCGTTTC CAACGAAATC chr1:125179939-125180439 + 54 6.28e-07 CGATAATTCC GTTTTTTTCCGTTTGGTGTTGATACCATTCG ATTCCATTCG chr12:123232743-12323324 - 19 6.28e-07 TAGCGGCCCC TTGAGTGTGGTGATGGGCTGGGGTGTGGGGT GACGGCTGCC chr12:130764516-13076501 + 13 6.77e-07 TGTCGTGATG TTATTGATGTGGTGTTGATGATGTCACAGTG TTGATGATGT chr5:116574678-116575178 + 67 7.84e-07 AAAGGAGAGC TGTGGTGTATGTGAGTGCGAGTGAGCGAGGC AGA chr19:38224231-38224731 - 59 1.21e-06 GTGTGAGTAG GAGTGTGTGGGAGGCTGTGAGTATCCGCGTG AATGTGTGTG chr6:27479358-27479858 + 9 1.49e-06 CTGAATTG CCTTGCGTATATTTGGTAGGGGAAACGTGTG ACTACAGAGC chr17:81253581-81254081 - 35 3.13e-06 ATGGAGATGG TGGTGATGATAGCGGTGATGGTGATGATGGT GACGGTGATG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:36837854-36838354 4e-16 54_[-1]_15 chr19:35947355-35947855 1e-15 42_[+1]_27 chr12:57111899-57112399 1e-15 48_[-1]_21 chr1:156661290-156661790 1e-15 65_[+1]_4 chr10:101830480-10183098 8.1e-14 1_[-1]_68 chr20:52972205-52972705 9.6e-14 13_[+1]_56 chr12:112387664-11238816 1.1e-12 38_[-1]_31 chr22:37844516-37845016 6.7e-12 17_[+1]_52 chr19:39033050-39033550 6.7e-12 45_[-1]_24 chr21:45591078-45591578 2.3e-11 9_[-1]_60 chr1:228782502-228783002 8.4e-11 38_[+1]_31 chr1:235078182-235078682 1.2e-10 [+1]_69 chr20:35616573-35617073 1.4e-10 20_[+1]_49 chr19:33249578-33250078 2.5e-10 26_[-1]_43 chr1:184386497-184386997 5.6e-10 56_[-1]_13 chr5:59303215-59303715 5.3e-09 3_[+1]_66 chr21:6565296-6565796 7.2e-09 19_[-1]_50 chr7:139339841-139340341 7.2e-09 5_[+1]_64 chr5:176591624-176592124 8.7e-09 18_[+1]_51 chr5:172958980-172959480 8.7e-09 30_[-1]_39 chr8:28401253-28401753 1.3e-08 [+1]_69 chr1:40691648-40692148 2.7e-08 17_[+1]_52 chr4:189234913-189235413 3e-08 21_[+1]_48 chr4:189233710-189234210 3e-08 34_[+1]_35 chr21:37366816-37367316 3.9e-08 54_[+1]_15 chr19:36851059-36851559 5.6e-08 64_[+1]_5 chr1:24642579-24643079 6.6e-08 27_[-1]_42 chr17:1293386-1293886 7.2e-08 4_[+1]_65 chr20:50165934-50166434 1.2e-07 69_[+1] chr19:36687092-36687592 1.3e-07 19_[-1]_50 chr1:28373345-28373845 1.7e-07 45_[+1]_24 chrUn_KI270467v1:2903-34 2.5e-07 40_[+1]_29 chr19:36604662-36605162 2.5e-07 68_[-1]_1 chr14:70359486-70359986 2.5e-07 19_[+1]_50 chr17:26603652-26604152 5.8e-07 27_[-1]_42 chr1:125179939-125180439 6.3e-07 53_[+1]_16 chr12:123232743-12323324 6.3e-07 18_[-1]_51 chr12:130764516-13076501 6.8e-07 12_[+1]_57 chr5:116574678-116575178 7.8e-07 66_[+1]_3 chr19:38224231-38224731 1.2e-06 58_[-1]_11 chr6:27479358-27479858 1.5e-06 8_[+1]_61 chr17:81253581-81254081 3.1e-06 34_[-1]_35 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK width=31 seqs=42 chr19:36837854-36838354 ( 55) GTGTGTGTGTATGTGTGTGTGTGTGTGTGTG 1 chr19:35947355-35947855 ( 43) GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1 chr12:57111899-57112399 ( 49) GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1 chr1:156661290-156661790 ( 66) GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1 chr10:101830480-10183098 ( 2) GCGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1 chr20:52972205-52972705 ( 14) GAGGGTGTGTGTGTGTGTTTGTGTGTGTGTG 1 chr12:112387664-11238816 ( 39) CTTTTTGTTTTTGTTTTTTTGTGTTTTTGTG 1 chr22:37844516-37845016 ( 18) TAATTTTTGTATTTTTAGTAGAGACGGGGTT 1 chr19:39033050-39033550 ( 46) TAATTTTTGTATTTTTAGTAGAGACGGGGTT 1 chr21:45591078-45591578 ( 10) TGTTATGTGTATCTGTGTGTGTGTGTGTGTC 1 chr1:228782502-228783002 ( 39) GTGTGTGTGTGTTGTTTGTGATGTGTGTGCG 1 chr1:235078182-235078682 ( 1) TATGTGTTATGTGTGTATGAGTATGTGTGTT 1 chr20:35616573-35617073 ( 21) CAATTTTTGTGTTTTTAGTAGAGACGGGGTT 1 chr19:33249578-33250078 ( 27) TGTGGTGTGTATCTGTGTGTGTGTGTGATGT 1 chr1:184386497-184386997 ( 57) GTGTGTGTGTGTGTGTACGTGTGTGCGCGCG 1 chr5:59303215-59303715 ( 4) TTTTTATTGCATTTGCTTTTGGGTTCTTGGT 1 chr21:6565296-6565796 ( 20) TGGTGTGTGTGGAGTGTGTGGAGTGTGTGGT 1 chr7:139339841-139340341 ( 6) CTAATTCTGTATTTTTAGTAGAGACAGGGTT 1 chr5:176591624-176592124 ( 19) GTGTTGGTGTTGAGGTGATGGTGATGGTTGT 1 chr5:172958980-172959480 ( 31) GTGTTCTTTTTTTTTTTTTTGAGACGGAGTC 1 chr8:28401253-28401753 ( 1) ATATGTGTGGGTGCGCGAGTGTGTATGTGTG 1 chr1:40691648-40692148 ( 18) AGGTGTGTGAGTGTGCGGGAGTTTCTGTGCG 1 chr4:189234913-189235413 ( 22) TGTTTGGTGTAGTTGTAGTAGTGCTCTGTGG 1 chr4:189233710-189234210 ( 35) TGTTTGGTGTAGTTGTAGTAGTGCTCTGTGG 1 chr21:37366816-37367316 ( 55) GAGTGCGAGTGTGTGTGCGAGGGAGCGTGTG 1 chr19:36851059-36851559 ( 65) GTGTGTGTGCGCGCGCGTTGGTGATATTGTT 1 chr1:24642579-24643079 ( 28) TCGTTGTGAAAGTTGTGATTGTGTAGGTTTT 1 chr17:1293386-1293886 ( 5) TTGAGTTTGATGATGTCGTGGGTTGTGTTTG 1 chr20:50165934-50166434 ( 70) TCATGCGTGCTTGGCTCTTTGTGATTATGTG 1 chr19:36687092-36687592 ( 20) CTGTGTATGCACCTGTGCGTGTGTGTTTGAT 1 chr1:28373345-28373845 ( 46) ATAATTTTATAATTTTTATAGAGACAGGTCT 1 chrUn_KI270467v1:2903-34 ( 41) TATTTTATGTACAGTATGTAATATATATTTT 1 chr19:36604662-36605162 ( 69) GGCTGCGTCCGTGTGTGGTGGTGTGAGTGGG 1 chr14:70359486-70359986 ( 20) TATTTGGTGCTCGGTCCTTAGTGAATGGTTT 1 chr17:26603652-26604152 ( 28) TATAGTTTTTATGTGAAGATGATTCCGTTTC 1 chr1:125179939-125180439 ( 54) GTTTTTTTCCGTTTGGTGTTGATACCATTCG 1 chr12:123232743-12323324 ( 19) TTGAGTGTGGTGATGGGCTGGGGTGTGGGGT 1 chr12:130764516-13076501 ( 13) TTATTGATGTGGTGTTGATGATGTCACAGTG 1 chr5:116574678-116575178 ( 67) TGTGGTGTATGTGAGTGCGAGTGAGCGAGGC 1 chr19:38224231-38224731 ( 59) GAGTGTGTGGGAGGCTGTGAGTATCCGCGTG 1 chr6:27479358-27479858 ( 9) CCTTGCGTATATTTGGTAGGGGAAACGTGTG 1 chr17:81253581-81254081 ( 35) TGGTGATGATAGCGGTGATGGTGATGATGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 12.0358 E= 6.0e-079 -134 -142 16 133 40 -175 -58 133 8 -374 58 78 -60 -1204 -175 212 -292 -1204 84 117 -192 -142 -94 189 -134 -374 95 66 -292 -1204 -274 236 -34 -274 121 -134 -134 -94 -216 194 108 -1204 50 -11 -192 -175 -58 183 -60 -175 50 89 -292 -274 -58 199 -1204 -274 106 66 -192 -142 -175 203 25 -216 65 25 -11 -142 6 108 -292 -1204 25 172 89 -1204 -42 125 -134 -1204 154 -1204 25 -1204 -142 189 -92 -1204 134 -92 99 -274 -1204 172 -60 -29 42 8 -60 -42 -94 140 -92 -374 121 -34 -92 -274 -58 183 -1204 -1204 121 54 -292 -142 -42 178 -1204 -175 65 117 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 42 E= 6.0e-079 0.071429 0.119048 0.357143 0.452381 0.238095 0.095238 0.214286 0.452381 0.190476 0.023810 0.476190 0.309524 0.119048 0.000000 0.095238 0.785714 0.023810 0.000000 0.571429 0.404762 0.047619 0.119048 0.166667 0.666667 0.071429 0.023810 0.619048 0.285714 0.023810 0.000000 0.047619 0.928571 0.142857 0.047619 0.738095 0.071429 0.071429 0.166667 0.071429 0.690476 0.380952 0.000000 0.452381 0.166667 0.047619 0.095238 0.214286 0.642857 0.119048 0.095238 0.452381 0.333333 0.023810 0.047619 0.214286 0.714286 0.000000 0.047619 0.666667 0.285714 0.047619 0.119048 0.095238 0.738095 0.214286 0.071429 0.500000 0.214286 0.166667 0.119048 0.333333 0.380952 0.023810 0.000000 0.380952 0.595238 0.333333 0.000000 0.238095 0.428571 0.071429 0.000000 0.928571 0.000000 0.214286 0.000000 0.119048 0.666667 0.095238 0.000000 0.809524 0.095238 0.357143 0.047619 0.000000 0.595238 0.119048 0.261905 0.428571 0.190476 0.119048 0.238095 0.166667 0.476190 0.095238 0.023810 0.738095 0.142857 0.095238 0.047619 0.214286 0.642857 0.000000 0.000000 0.738095 0.261905 0.023810 0.119048 0.238095 0.619048 0.000000 0.095238 0.500000 0.404762 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KWKTKTGTGTRTKTGTGKKDGTGWSYGTGTK MEME-1 regular expression -------------------------------------------------------------------------------- [TG][TAG][GT]T[GT]T[GT]TGT[GA][TG][GT][TG][GT]T[GAT][TG][TG][TAG]G[TA]G[TA][GC][TC]G[TG][GT][TG][GT] -------------------------------------------------------------------------------- Time 368.23 secs. ******************************************************************************** ******************************************************************************** MOTIF TYCCKCCYCCKCYYCC MEME-2 width = 16 sites = 150 llr = 1305 E-value = 8.2e-034 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::::2:::::: pos.-specific C 2677177486:86479 probability G 2:::3::2:241:::: matrix T 6432532421613631 bits 2.5 2.2 2.0 1.7 Relative 1.5 Entropy 1.2 * * (12.6 bits) 1.0 * ** * * 0.7 ******* * ****** 0.5 ********* ****** 0.2 **************** 0.0 ---------------- Multilevel TCCCTCCTCCTCCTCC consensus CTTTGTTC G TCT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr15:70892196-70892696 + 69 9.81e-10 CTTTGATATC TTCCTCCTCCTCCTCC CTGCGCTGCT chr21:39183023-39183523 + 82 8.39e-08 TCTCcctccg cccctcctcctcctcc tct chr11:78079601-78080101 + 33 1.31e-07 AGCGGTCAGC TTTCTCCTCCTCCTCT GCGCGCCGGA chr17:67993797-67994297 - 75 2.99e-07 AGCCTCCCCT TCCCTCTTCTTCCTTC TCGGCTTCCT chr4:102827343-102827843 + 30 3.54e-07 CCACGCTCCG CCCCTCCCCCTCCTCC TGCCTCTTCA chr17:59209674-59210174 - 49 4.29e-07 GTCACTTGAG TTCCGCCTCCTCTTCT CCTCTCCTAG chrX:120309452-120309952 + 75 6.29e-07 tcgcgctctc tctctctccctctccc tctgtatgtg chr12:95217727-95218227 - 2 1.05e-06 CTTCCTCGAT TTCCGTCTCGTCCTTC T chr5:14664200-14664700 + 20 1.05e-06 AAGACCAGAC TTCCTCCTCCTCACCC AGGACGCTCC chr3:155854229-155854729 + 47 1.24e-06 CTCTAACAGG TCCCTTCCCAGCCTCC AGAGCAAGCC chr12:389118-389618 + 73 1.24e-06 CTGGCCTTTC CTTCTTCTTCTCTTCC CCGGCAGCAC chr21:33025409-33025909 + 29 1.70e-06 CCCTTGAGCC GCCCTTCTCCTCCCCC TCGCCTCCTC chr19:40403805-40404305 + 42 1.70e-06 caagggatcc tcccgcctcggcctcc caaagtgctg chr12:55829110-55829610 - 29 1.97e-06 CAAGCGATTC TTCTGCCTCAGCCTCC CGAGTAGCTG chr6:30647081-30647581 - 32 2.31e-06 CCCCCTCTCC TCCCTCCCTCTTCTCC TCCGCTCACC chr14:90526500-90527000 + 18 2.31e-06 tttataaggg tttttccccctccttt tgcacggcac chr13:40770962-40771462 + 43 2.31e-06 ACGTCCCCGC CCTCTCTTCCGCTTCC GGCCTGGCGC chr15:65517256-65517756 - 1 3.11e-06 CAGTATCCGC CCCCTTCTCCTTCTCC chr1:224113959-224114459 + 33 3.11e-06 gcgacggcgg TTCCTCTTTGGCCTCC GGCTCTACCC chr17:45161187-45161687 + 85 3.11e-06 GCGCAGCGAG TCCCTCCGCTGCCTCC chr19:13747305-13747805 + 74 3.11e-06 caagcaattc ttttgcctcagcctcc caagtagctg chr10:104231879-10423237 - 25 3.59e-06 CCAAGTCCCC TCCTCCCTCCTCTCCC TCCGGTTCCT chr12:53501173-53501673 - 20 3.59e-06 CTTCACTCAT TCCCTCCTCCGTCCCC GCGGGCGCCA chr5:41904198-41904698 - 74 3.59e-06 CGCCCGCCTC CCTCTCCTCCGCTCCC TCACCATCTT chr15:49046311-49046811 - 8 4.15e-06 GCCCATTCGG GCCCTCCTCGGCTTCC GTCCCAG chr22:46013699-46014199 + 48 4.15e-06 CCCTCCACAT TCCCGCCTGCTCCTCC GGGCCTGCCC chr12:123458009-12345850 - 48 4.15e-06 TGGGCCGCAC TCCCTCTTCCTTCTCT CCGGCGTGGG chr1:155244567-155245067 - 83 4.76e-06 TC TCTCTCTCTCTCTCTC GCTCGCTCTC chr21:32771773-32772273 - 1 4.76e-06 GGTGTGGGGC TCTCTCTCTCTCTCTC chr6:131628016-131628516 - 20 4.76e-06 CGCGTACCGG GCCCTTCCCGTCTTCC GTACAGGTTC chr1:26695404-26695904 + 4 4.76e-06 TTG TTCTCTCCCCTCCTCC TTTGTGAAGG chr17:4987228-4987728 - 21 4.76e-06 ACCTCCCGCT TCCGTCCTCCTCCCCC GCGCCAGGGG chr17:7836699-7837199 + 71 4.76e-06 CCCGTGCCAT CTCTTTCCCCTCTCCC TTCCCGTGGT chr1:225774702-225775202 + 61 4.76e-06 acttccccct tctctctctctctctc ctgctgccac chr19:2945126-2945626 - 13 4.76e-06 GGGACTCCGT GCCCTTCCTCTCCTCC CCGCACGAGG chr2:223957184-223957684 + 55 5.44e-06 GCCCGACTAC TTTCGTTCCGTCTTCC ATCGTTTTCT chr15:79923282-79923782 - 62 5.44e-06 GGACGCCTCT TTCCTCCGGCTCTTCC CTTGTTGCTG chr8:23246516-23247016 - 51 5.44e-06 AGGACATGCG CTCCTCGTCCTCCTCC CACTCGGGGG chr5:69234802-69235302 - 53 5.44e-06 TCCGCTTGGG GCCCTCCCCGTCCTTC CAGAGAGCCT chr19:38544104-38544604 + 47 6.23e-06 ATTTCCATAA TCCTTGTTCCTCTTTC CCTCACCCCT chr21:38805374-38805874 - 25 6.23e-06 GGCCCAACCT TCCCTCCGCCTCCTGC TGTCACTCGG chr12:109998985-10999948 - 12 6.23e-06 GTCCCCAGCT TCTTTCCCCCTGCTCC AGTAGCCCCA chr1:234723978-234724478 - 62 7.11e-06 GCTCCGAGTT GTTTTTCTCCTCTCTC CTCCAACTGT chr6:39114704-39115204 + 78 7.11e-06 TCGCTGCTGC TTCCGCCTTCTCTCCT GGGGTTT chr17:59291798-59292298 + 43 7.11e-06 taagtgatcc tcccacctcagcctcc tgaatagctg chr10:17201431-17201931 + 51 8.07e-06 TGCCGGTCCG TCGCTCCTCCTCCCTC CATCGCGCCG chr12:68808034-68808534 - 8 8.07e-06 GGGCTCGGCT TCTTGCTCCATCTTTC CGACACA chr22:46658962-46659462 + 3 8.07e-06 CC TCCTGCTTCGGCCTCC CTCTCAGCCT chr13:95677024-95677524 + 2 8.07e-06 T TTCCTCCTCTTCACTC GCGAGCCCTC chr10:42782452-42782952 + 76 9.19e-06 CATGCCGGTC TCTTTTTTCTGCCTTC TTGTTTCCC chr22:37686125-37686625 - 81 9.19e-06 ACCA TCTCGCTTCTTCTTCT TGTTGCGGCC chr17:6651800-6652300 + 63 9.19e-06 GCAGCGAGGG GCCCTCCCTCTCCCCC TCGGGGAAGC chr12:107093864-10709436 - 44 9.19e-06 ACTCTCCTCC TTCCACTCCATCCTCC CCTCACTCTC chr21:25607256-25607756 + 47 1.04e-05 TCGCGCGCAA GTCCTTCTCCGCCCTC CTCCCCCGGA chr9:95875704-95876204 + 76 1.18e-05 CCACCTTGCT GTCCTCCGCCGCCTTC CGGGTGTTA chr13:52194223-52194723 + 24 1.33e-05 CATCCCCCGC GCTCTCCTCCGTTTCC GGTCTGGCTT chr1:46340683-46341183 - 50 1.33e-05 CCCTCACTTT TCCCTCCTGCGCCCCC AGCCGGACCT chr20:38435079-38435579 - 22 1.50e-05 TCCTTCGCCG TCCCTCGCCGTCCTTC GCCATCGCAC chr1:111990050-111990550 - 11 1.50e-05 ACGCACTAGG CTCTGCCTCGTCTCCC CACCCCCCGC chr1:40691648-40692148 - 59 1.68e-05 CTGCCCCTCC CCCCGCCGCCGCTTCC CTATCACCCT chr5:138542798-138543298 + 13 1.68e-05 AGCGGCCCCC TTCCTCGCCATCCCCC AGAGGCCCTC chr7:139339841-139340341 + 85 1.68e-05 aagatgatcc gcccgcctcggcctcc chr2:241102113-241102613 + 4 1.89e-05 CGG TCCTCCCCCGTCCTTC ACTTCCGGCC chr1:224615761-224616261 + 41 2.12e-05 ACACACCATA CCCTTCCGCAGCTTCC CACCTCCTCC chr12:123232743-12323324 + 77 2.12e-05 GTCTCCTAAG TCTCGTCTCCTGTCCC CAGCGGCC chr16:30526882-30527382 + 55 2.12e-05 GGGGGCGGTG TCTCGCTCCCTCCCCT CCCGGGCCTC chr6:157323318-157323818 + 55 2.64e-05 AGGAGAAAGG TTCCGCTACCGCCTCC TCCTGTGCAA chr17:68511868-68512368 - 26 2.64e-05 GTCGCCTTTG TTCCTCCGCCTGCTCT TCGCTCTCTC chr16:30378350-30378850 + 57 2.95e-05 GGTGCGTGCT CACCTCTTCGTCTTTC TCGCGGATCA chr21:37072495-37072995 - 40 2.95e-05 GAACCCCCCT CCCTGCCCTATCCTCC GCCACCCCTT chr19:39390701-39391201 - 10 3.28e-05 AGTCGGCACG CCCCTCTGCGTCCCCC TTCGGTCCC chr6:24774896-24775396 - 25 3.28e-05 CGTACCCACT TCCTGCCGCCTCTTGC CCACTTACTG chr6:87322344-87322844 + 5 3.28e-05 GGGC GCCCTCCGCCGCTCTC TCTAGCAggc chr17:18087643-18088143 + 78 3.28e-05 CGAGAACGCT GTTCTCTTTGGCTTCC GGGCGCA chr20:44210257-44210757 - 17 3.28e-05 CCACGCTCTC TCCCCTTCCCGCCTTC CCGTCCTCCC chr11:10931252-10931752 - 51 3.64e-05 TTACGCGCTG CTCCGTCCCGGCCTCC GCACACTCCC chr19:14496011-14496511 + 51 3.64e-05 TCCAGAGGGA TCCCTCCGCCTCGCCC GGCTCTTCCC chr6:16759816-16760316 + 62 3.64e-05 CCCGTCCGGC CCCCTTCCCTGCCCCC TGCGGGACCG chr17:50560473-50560973 + 54 3.64e-05 GCGCGGGgct cctcgccgccgctttc gctcgctcgc chr19:38336503-38337003 - 85 4.04e-05 . TCCTTATTCCGCCCCC TCCCTGTATT chr9:129110777-129111277 + 17 4.04e-05 CGTCCAGCTG TCTCTCCCCTGTCCCC ACATGTCTTC chr12:49130967-49131467 + 81 4.04e-05 CCGCCGGCTC GCTTTTCCCTGCTTCC CTGA chr16:690211-690711 + 23 4.48e-05 AGTGGTCCTC TTCTTACCCATCCCTC TCAGGAAGTG chr21:41766760-41767260 + 63 4.48e-05 GCCCATGGGG TCCCGCCGTCGCCCTC CATCGCGCAC chr13:111153240-11115374 - 17 4.95e-05 CGCGCGCGGC CACCGCCGCCTCCTCC TGTCCAGTCT chr19:17337061-17337561 + 34 4.95e-05 CTGTGCCAAA CTCTGTCCTTTCTTCC ATTCCTTATT chr7:97117342-97117842 + 81 4.95e-05 TCGCGCGCCC TCTTTCGTCTGCCTTC CGGT chr21:43857406-43857906 - 50 4.95e-05 CAGGTGATCT GCCCACCTCAGCCTCC CAAAGTGCTG chr1:206612159-206612659 - 3 5.47e-05 ATTCCCTGGC TTCTGTGCTCTCTTCC CC chrX:104156557-104157057 + 5 5.47e-05 GTTT CCCCTACTCCTCATCC CCTCGCAACT chr7:155328565-155329065 + 34 5.47e-05 CACATCCTCA TCTCTCCCTCTCCCCA AAGACACACA chr22:42188800-42189300 - 11 5.47e-05 ACAAAGCAGT TTGTTCCCCTTCCCCC CAGGTAGCTC chr12:28190407-28190907 - 14 5.47e-05 CTTACCTGCT CCCCTCTCTCGCTCTC CGCTGCCGCC chr22:38681725-38682225 + 22 5.47e-05 GCTGCGCTCA CCTCCTTTCCGCTTCC GGTGTCCCCT chr12:27710712-27711212 + 50 5.47e-05 CTGCGTGAGT GTCTGTCTCGTCTTCT CTGGGCTTTG chr20:37095802-37096302 + 54 5.47e-05 GTCATCCACC GTCTGCCTCCGCTTTT CTCCTCAAAA chr1:167714407-167714907 - 54 6.04e-05 TTGTTCCGCC TCTCACCTCGTGTTCC GAGCAACCAC chr12:1202943-1203443 + 23 6.04e-05 caaccgattc ttgtgcctcagcctcc tgagtacctg chr6:85593463-85593963 + 24 6.04e-05 CTGCTTCAGC TTCTGCCCCATCGTCC GCACCCAGGG chr20:58650974-58651474 - 25 6.65e-05 CCTGGCCCTC TTCCTGTCCGTCCCTC GCGAGTGCCC chr5:38556672-38557172 - 26 6.65e-05 GCCGCCTCGC TCTCCCCTGCGCTTCC ATGACCTTCT chr1:230868091-230868591 + 75 6.65e-05 TCTCGCGGAT CTTCTCCTTGTCCTGC ATGATCTTCC chr13:49936023-49936523 + 78 6.65e-05 CGCCGCTCAG CTCCGTCTCCTGCCCC CGCCCGA chr12:109573064-10957356 + 82 7.33e-05 CAGCCACTCA CCTGTCCCCGTCTTCC ACG chr21:42973818-42974318 - 26 7.33e-05 CCTCGCAGCC TTCCTCCCCAGGCTCT GGAGCCCGGG chr5:176388756-176389256 - 69 8.05e-05 CGCTCTGGTC CTTCTCTACTTCCTTC CCTCCGACAT chr14:30559083-30559583 - 28 8.05e-05 CCACCCCACG GTCCTGCTTCTCTCTC TGGAACGTTC chr6:85679050-85679550 - 21 8.05e-05 ACGTGGCGCT TTCCGCTTTTTCACCC AAGCGTTTCT chr17:74430752-74431252 + 77 8.05e-05 CGCCCTGCCC TCCCTCCGCGTCTCCA GGGCCCTG chr3:112561472-112561972 - 13 8.05e-05 GTGCCTGCCG CCCCGCCCCCTCGTCC CGCCCGTCCC chr9:128947576-128948076 - 33 8.05e-05 CCGCCTCCAA TTCCCGCCCCGCTTCC GCTCGGCTTT chr13:110965221-11096572 + 5 8.83e-05 tcca tcctgactcattctcc accctgactc chr11:47578740-47579240 + 27 8.83e-05 AGCCCGGAAC CTCCGCTTCCGGCTCC ACGTCCGCCC chr19:33373103-33373603 - 41 8.83e-05 ACTGTTTTGG TTTCGCCGCGTCCCTT GGAAGCCCCC chr4:2009184-2009684 + 33 8.83e-05 CCCGCTGTCC GCTCTTCGCTTTTTCC CCGCTTGGGT chr2:37925247-37925747 - 44 9.69e-05 CCACCGCAAG TATTTCCGCTTCCCTC CGCAAGTCCC chr20:63657984-63658484 - 43 9.69e-05 GGGTCCGCCT GCTCTTCGGCTCCTCC AGGCCTACAC chr1:10854793-10855293 + 36 9.69e-05 agcctaacca tatcatcctctcttcc tggtctgccc chrX:41084836-41085336 + 76 9.69e-05 TTTACCGCAT TGTCTTCCCCTCCCCC ACCCTAGCT chr12:124914536-12491503 + 6 1.06e-04 CTACT TTTCCTCGCCTGTTCC GCTCTCTGGA chr11:57741077-57741577 + 12 1.06e-04 CGGACCTAGT CTCCGCCCCTTCCTGC TGTGTTCACC chr2:197499607-197500107 + 71 1.06e-04 AGCCCGTGTC CCCTCCCTCCGCCTCT ACTCCCGCCC chr21:36980450-36980950 + 20 1.06e-04 CGCGGAGCGC TCCTGGCCCCGCTCCC GCCAGGCTCC chr19:40420974-40421474 + 38 1.06e-04 ACCGTCCAGC CCCCTGCGCCTCTCTC CATGCGCACC chr10:75111529-75112029 - 76 1.06e-04 AGGTCGCGG TCCCTCGGCAGCCCCC GGCTCCATCC chr1:183471821-183472321 - 48 1.16e-04 CAAAGTCTTC CCCCTTCTTATCACTC CTGCCGATTT chr1:53220252-53220752 + 29 1.27e-04 GCGCACCCAC TCGCTTCATCTCCTCC TGGCGCGAGC chr19:40920894-40921394 + 52 1.27e-04 AATCAGGATT GTTTATCTTATCCTCC TGGGTCAAAG chr6:85642924-85643424 + 15 1.27e-04 TCTCGGCCTT TCTTATTCCCGCCCCC CGCTCCTTTA chr5:181215878-181216378 + 16 1.27e-04 caagctattc tcgtgccccagcctcc caagtagctg chr12:63419081-63419581 + 68 1.27e-04 tcattccaat tacctgctcattctcc gcccagactc chr20:45934618-45935118 + 62 1.27e-04 GGGGCGGCGG CCCCTCCGGCGCTTTC TGCTCGGGAC chr22:19432258-19432758 - 78 1.38e-04 TCATGGC TACCCTCGCCGCTTCC GGGCGTGCGC chr10:110497337-11049783 + 57 1.51e-04 CCCACGGCGC TTCCTCCTCGGTCCGC ACCGCGAGGG chr12:89709711-89710211 - 42 1.51e-04 CGCCAGGAGC GCTCGCCCTCGCCCTC CCGCTGGCTC chrX:72276898-72277398 - 45 1.64e-04 TTAGGACGTA TCCGCCTCCATCCTCC CCCGGCCGGG chr15:77419803-77420303 + 42 1.64e-04 CACCATCACC GTCCGTCCCGTCCCCT TCCTGGTGAC chr10:102713943-10271444 - 73 1.64e-04 CGGCCGGTTA TCCCCCTCCCGTCCCC AGGCCCAGGG chr19:44500175-44500675 + 37 1.64e-04 GTTAAGCTAG TTCGGTCCCCTCTCCT AGTCAGCATC chr7:100705380-100705880 + 71 1.64e-04 TGTCCCTCAG TTCCCCCTCGGTCCTC GGGCCACAGG chr5:177086847-177087347 - 80 1.78e-04 CGTAG CCCCGCCGCCTCTCGC CCCCTGGCGG chr15:72231019-72231519 + 22 1.94e-04 GCCGCCGCAA TCCCTCCGCCGCCCCG CCCTCTGCCC chr17:82065643-82066143 - 45 2.10e-04 CGCCGCGACC TCTCGTCGCCGGTCCC CTCGGAGCCG chr19:44212430-44212930 - 74 2.10e-04 AGAGCAAACT TCCCGCCCTCGGCCTC TCGGCCTCCG chr21:29052239-29052739 - 62 2.10e-04 ATGGGAGCAG GTCTTTCCCATCCTTA TTCTTGATAG chr7:108569869-108570369 - 37 2.47e-04 TCCCCACGAC CCCGGCCTCGTCCCTC ACCTGCACCC chr15:75201730-75202230 - 72 2.89e-04 CCCAGGCGGC CTCCGCGTCCGCATCC TCCAGCGTCT chr19:58327057-58327557 - 35 2.89e-04 TGGTCCGTCA GTCCGTCACATCCTCT GCGCGTGTGT chr6:7541539-7542039 + 65 3.12e-04 CCTTCCGCAC TCCCGCCCGGTTCCCC GGCCGTCCGC chr5:150000331-150000831 + 9 4.20e-04 GCCACAGC TTCCTCCTCCGCCCGG GACCTCTGGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:70892196-70892696 9.8e-10 68_[+2]_16 chr21:39183023-39183523 8.4e-08 81_[+2]_3 chr11:78079601-78080101 1.3e-07 32_[+2]_52 chr17:67993797-67994297 3e-07 74_[-2]_10 chr4:102827343-102827843 3.5e-07 29_[+2]_55 chr17:59209674-59210174 4.3e-07 48_[-2]_36 chrX:120309452-120309952 6.3e-07 74_[+2]_10 chr12:95217727-95218227 1.1e-06 1_[-2]_83 chr5:14664200-14664700 1.1e-06 19_[+2]_65 chr3:155854229-155854729 1.2e-06 46_[+2]_38 chr12:389118-389618 1.2e-06 72_[+2]_12 chr21:33025409-33025909 1.7e-06 28_[+2]_56 chr19:40403805-40404305 1.7e-06 41_[+2]_43 chr12:55829110-55829610 2e-06 28_[-2]_56 chr6:30647081-30647581 2.3e-06 31_[-2]_53 chr14:90526500-90527000 2.3e-06 17_[+2]_67 chr13:40770962-40771462 2.3e-06 42_[+2]_42 chr15:65517256-65517756 3.1e-06 [-2]_84 chr1:224113959-224114459 3.1e-06 32_[+2]_52 chr17:45161187-45161687 3.1e-06 84_[+2] chr19:13747305-13747805 3.1e-06 73_[+2]_11 chr10:104231879-10423237 3.6e-06 24_[-2]_60 chr12:53501173-53501673 3.6e-06 19_[-2]_65 chr5:41904198-41904698 3.6e-06 73_[-2]_11 chr15:49046311-49046811 4.1e-06 7_[-2]_77 chr22:46013699-46014199 4.1e-06 47_[+2]_37 chr12:123458009-12345850 4.1e-06 47_[-2]_37 chr1:155244567-155245067 4.8e-06 82_[-2]_2 chr21:32771773-32772273 4.8e-06 [-2]_84 chr6:131628016-131628516 4.8e-06 19_[-2]_65 chr1:26695404-26695904 4.8e-06 3_[+2]_81 chr17:4987228-4987728 4.8e-06 20_[-2]_64 chr17:7836699-7837199 4.8e-06 70_[+2]_14 chr1:225774702-225775202 4.8e-06 60_[+2]_24 chr19:2945126-2945626 4.8e-06 12_[-2]_72 chr2:223957184-223957684 5.4e-06 54_[+2]_30 chr15:79923282-79923782 5.4e-06 61_[-2]_23 chr8:23246516-23247016 5.4e-06 50_[-2]_34 chr5:69234802-69235302 5.4e-06 52_[-2]_32 chr19:38544104-38544604 6.2e-06 46_[+2]_38 chr21:38805374-38805874 6.2e-06 24_[-2]_60 chr12:109998985-10999948 6.2e-06 11_[-2]_73 chr1:234723978-234724478 7.1e-06 61_[-2]_23 chr6:39114704-39115204 7.1e-06 77_[+2]_7 chr17:59291798-59292298 7.1e-06 42_[+2]_42 chr10:17201431-17201931 8.1e-06 50_[+2]_34 chr12:68808034-68808534 8.1e-06 7_[-2]_77 chr22:46658962-46659462 8.1e-06 2_[+2]_82 chr13:95677024-95677524 8.1e-06 1_[+2]_83 chr10:42782452-42782952 9.2e-06 75_[+2]_9 chr22:37686125-37686625 9.2e-06 80_[-2]_4 chr17:6651800-6652300 9.2e-06 62_[+2]_22 chr12:107093864-10709436 9.2e-06 43_[-2]_41 chr21:25607256-25607756 1e-05 46_[+2]_38 chr9:95875704-95876204 1.2e-05 75_[+2]_9 chr13:52194223-52194723 1.3e-05 23_[+2]_61 chr1:46340683-46341183 1.3e-05 49_[-2]_35 chr20:38435079-38435579 1.5e-05 21_[-2]_63 chr1:111990050-111990550 1.5e-05 10_[-2]_74 chr1:40691648-40692148 1.7e-05 58_[-2]_26 chr5:138542798-138543298 1.7e-05 12_[+2]_72 chr7:139339841-139340341 1.7e-05 84_[+2] chr2:241102113-241102613 1.9e-05 3_[+2]_81 chr1:224615761-224616261 2.1e-05 40_[+2]_44 chr12:123232743-12323324 2.1e-05 76_[+2]_8 chr16:30526882-30527382 2.1e-05 54_[+2]_30 chr6:157323318-157323818 2.6e-05 54_[+2]_30 chr17:68511868-68512368 2.6e-05 25_[-2]_59 chr16:30378350-30378850 2.9e-05 56_[+2]_28 chr21:37072495-37072995 2.9e-05 39_[-2]_45 chr19:39390701-39391201 3.3e-05 9_[-2]_75 chr6:24774896-24775396 3.3e-05 24_[-2]_60 chr6:87322344-87322844 3.3e-05 4_[+2]_80 chr17:18087643-18088143 3.3e-05 77_[+2]_7 chr20:44210257-44210757 3.3e-05 16_[-2]_68 chr11:10931252-10931752 3.6e-05 50_[-2]_34 chr19:14496011-14496511 3.6e-05 50_[+2]_34 chr6:16759816-16760316 3.6e-05 61_[+2]_23 chr17:50560473-50560973 3.6e-05 53_[+2]_31 chr19:38336503-38337003 4e-05 84_[-2] chr9:129110777-129111277 4e-05 16_[+2]_68 chr12:49130967-49131467 4e-05 80_[+2]_4 chr16:690211-690711 4.5e-05 22_[+2]_62 chr21:41766760-41767260 4.5e-05 62_[+2]_22 chr13:111153240-11115374 5e-05 16_[-2]_68 chr19:17337061-17337561 5e-05 33_[+2]_51 chr7:97117342-97117842 5e-05 80_[+2]_4 chr21:43857406-43857906 5e-05 49_[-2]_35 chr1:206612159-206612659 5.5e-05 2_[-2]_82 chrX:104156557-104157057 5.5e-05 4_[+2]_80 chr7:155328565-155329065 5.5e-05 33_[+2]_51 chr22:42188800-42189300 5.5e-05 10_[-2]_74 chr12:28190407-28190907 5.5e-05 13_[-2]_71 chr22:38681725-38682225 5.5e-05 21_[+2]_63 chr12:27710712-27711212 5.5e-05 49_[+2]_35 chr20:37095802-37096302 5.5e-05 53_[+2]_31 chr1:167714407-167714907 6e-05 53_[-2]_31 chr12:1202943-1203443 6e-05 22_[+2]_62 chr6:85593463-85593963 6e-05 23_[+2]_61 chr20:58650974-58651474 6.7e-05 24_[-2]_60 chr5:38556672-38557172 6.7e-05 25_[-2]_59 chr1:230868091-230868591 6.7e-05 74_[+2]_10 chr13:49936023-49936523 6.7e-05 77_[+2]_7 chr12:109573064-10957356 7.3e-05 81_[+2]_3 chr21:42973818-42974318 7.3e-05 25_[-2]_59 chr5:176388756-176389256 8.1e-05 68_[-2]_16 chr14:30559083-30559583 8.1e-05 27_[-2]_57 chr6:85679050-85679550 8.1e-05 20_[-2]_64 chr17:74430752-74431252 8.1e-05 76_[+2]_8 chr3:112561472-112561972 8.1e-05 12_[-2]_72 chr9:128947576-128948076 8.1e-05 32_[-2]_52 chr13:110965221-11096572 8.8e-05 4_[+2]_80 chr11:47578740-47579240 8.8e-05 26_[+2]_58 chr19:33373103-33373603 8.8e-05 40_[-2]_44 chr4:2009184-2009684 8.8e-05 32_[+2]_52 chr2:37925247-37925747 9.7e-05 43_[-2]_41 chr20:63657984-63658484 9.7e-05 42_[-2]_42 chr1:10854793-10855293 9.7e-05 35_[+2]_49 chrX:41084836-41085336 9.7e-05 75_[+2]_9 chr12:124914536-12491503 0.00011 5_[+2]_79 chr11:57741077-57741577 0.00011 11_[+2]_73 chr2:197499607-197500107 0.00011 70_[+2]_14 chr21:36980450-36980950 0.00011 19_[+2]_65 chr19:40420974-40421474 0.00011 37_[+2]_47 chr10:75111529-75112029 0.00011 75_[-2]_9 chr1:183471821-183472321 0.00012 47_[-2]_37 chr1:53220252-53220752 0.00013 28_[+2]_56 chr19:40920894-40921394 0.00013 51_[+2]_33 chr6:85642924-85643424 0.00013 14_[+2]_70 chr5:181215878-181216378 0.00013 15_[+2]_69 chr12:63419081-63419581 0.00013 67_[+2]_17 chr20:45934618-45935118 0.00013 61_[+2]_23 chr22:19432258-19432758 0.00014 77_[-2]_7 chr10:110497337-11049783 0.00015 56_[+2]_28 chr12:89709711-89710211 0.00015 41_[-2]_43 chrX:72276898-72277398 0.00016 44_[-2]_40 chr15:77419803-77420303 0.00016 41_[+2]_43 chr10:102713943-10271444 0.00016 72_[-2]_12 chr19:44500175-44500675 0.00016 36_[+2]_48 chr7:100705380-100705880 0.00016 70_[+2]_14 chr5:177086847-177087347 0.00018 79_[-2]_5 chr15:72231019-72231519 0.00019 21_[+2]_63 chr17:82065643-82066143 0.00021 44_[-2]_40 chr19:44212430-44212930 0.00021 73_[-2]_11 chr21:29052239-29052739 0.00021 61_[-2]_23 chr7:108569869-108570369 0.00025 36_[-2]_48 chr15:75201730-75202230 0.00029 71_[-2]_13 chr19:58327057-58327557 0.00029 34_[-2]_50 chr6:7541539-7542039 0.00031 64_[+2]_20 chr5:150000331-150000831 0.00042 8_[+2]_76 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYCCKCCYCCKCYYCC width=16 seqs=150 chr15:70892196-70892696 ( 69) TTCCTCCTCCTCCTCC 1 chr21:39183023-39183523 ( 82) CCCCTCCTCCTCCTCC 1 chr11:78079601-78080101 ( 33) TTTCTCCTCCTCCTCT 1 chr17:67993797-67994297 ( 75) TCCCTCTTCTTCCTTC 1 chr4:102827343-102827843 ( 30) CCCCTCCCCCTCCTCC 1 chr17:59209674-59210174 ( 49) TTCCGCCTCCTCTTCT 1 chrX:120309452-120309952 ( 75) TCTCTCTCCCTCTCCC 1 chr12:95217727-95218227 ( 2) TTCCGTCTCGTCCTTC 1 chr5:14664200-14664700 ( 20) TTCCTCCTCCTCACCC 1 chr3:155854229-155854729 ( 47) TCCCTTCCCAGCCTCC 1 chr12:389118-389618 ( 73) CTTCTTCTTCTCTTCC 1 chr21:33025409-33025909 ( 29) GCCCTTCTCCTCCCCC 1 chr19:40403805-40404305 ( 42) TCCCGCCTCGGCCTCC 1 chr12:55829110-55829610 ( 29) TTCTGCCTCAGCCTCC 1 chr6:30647081-30647581 ( 32) TCCCTCCCTCTTCTCC 1 chr14:90526500-90527000 ( 18) TTTTTCCCCCTCCTTT 1 chr13:40770962-40771462 ( 43) CCTCTCTTCCGCTTCC 1 chr15:65517256-65517756 ( 1) CCCCTTCTCCTTCTCC 1 chr1:224113959-224114459 ( 33) TTCCTCTTTGGCCTCC 1 chr17:45161187-45161687 ( 85) TCCCTCCGCTGCCTCC 1 chr19:13747305-13747805 ( 74) TTTTGCCTCAGCCTCC 1 chr10:104231879-10423237 ( 25) TCCTCCCTCCTCTCCC 1 chr12:53501173-53501673 ( 20) TCCCTCCTCCGTCCCC 1 chr5:41904198-41904698 ( 74) CCTCTCCTCCGCTCCC 1 chr15:49046311-49046811 ( 8) GCCCTCCTCGGCTTCC 1 chr22:46013699-46014199 ( 48) TCCCGCCTGCTCCTCC 1 chr12:123458009-12345850 ( 48) TCCCTCTTCCTTCTCT 1 chr1:155244567-155245067 ( 83) TCTCTCTCTCTCTCTC 1 chr21:32771773-32772273 ( 1) TCTCTCTCTCTCTCTC 1 chr6:131628016-131628516 ( 20) GCCCTTCCCGTCTTCC 1 chr1:26695404-26695904 ( 4) TTCTCTCCCCTCCTCC 1 chr17:4987228-4987728 ( 21) TCCGTCCTCCTCCCCC 1 chr17:7836699-7837199 ( 71) CTCTTTCCCCTCTCCC 1 chr1:225774702-225775202 ( 61) TCTCTCTCTCTCTCTC 1 chr19:2945126-2945626 ( 13) GCCCTTCCTCTCCTCC 1 chr2:223957184-223957684 ( 55) TTTCGTTCCGTCTTCC 1 chr15:79923282-79923782 ( 62) TTCCTCCGGCTCTTCC 1 chr8:23246516-23247016 ( 51) CTCCTCGTCCTCCTCC 1 chr5:69234802-69235302 ( 53) GCCCTCCCCGTCCTTC 1 chr19:38544104-38544604 ( 47) TCCTTGTTCCTCTTTC 1 chr21:38805374-38805874 ( 25) TCCCTCCGCCTCCTGC 1 chr12:109998985-10999948 ( 12) TCTTTCCCCCTGCTCC 1 chr1:234723978-234724478 ( 62) GTTTTTCTCCTCTCTC 1 chr6:39114704-39115204 ( 78) TTCCGCCTTCTCTCCT 1 chr17:59291798-59292298 ( 43) TCCCACCTCAGCCTCC 1 chr10:17201431-17201931 ( 51) TCGCTCCTCCTCCCTC 1 chr12:68808034-68808534 ( 8) TCTTGCTCCATCTTTC 1 chr22:46658962-46659462 ( 3) TCCTGCTTCGGCCTCC 1 chr13:95677024-95677524 ( 2) TTCCTCCTCTTCACTC 1 chr10:42782452-42782952 ( 76) TCTTTTTTCTGCCTTC 1 chr22:37686125-37686625 ( 81) TCTCGCTTCTTCTTCT 1 chr17:6651800-6652300 ( 63) GCCCTCCCTCTCCCCC 1 chr12:107093864-10709436 ( 44) TTCCACTCCATCCTCC 1 chr21:25607256-25607756 ( 47) GTCCTTCTCCGCCCTC 1 chr9:95875704-95876204 ( 76) GTCCTCCGCCGCCTTC 1 chr13:52194223-52194723 ( 24) GCTCTCCTCCGTTTCC 1 chr1:46340683-46341183 ( 50) TCCCTCCTGCGCCCCC 1 chr20:38435079-38435579 ( 22) TCCCTCGCCGTCCTTC 1 chr1:111990050-111990550 ( 11) CTCTGCCTCGTCTCCC 1 chr1:40691648-40692148 ( 59) CCCCGCCGCCGCTTCC 1 chr5:138542798-138543298 ( 13) TTCCTCGCCATCCCCC 1 chr7:139339841-139340341 ( 85) GCCCGCCTCGGCCTCC 1 chr2:241102113-241102613 ( 4) TCCTCCCCCGTCCTTC 1 chr1:224615761-224616261 ( 41) CCCTTCCGCAGCTTCC 1 chr12:123232743-12323324 ( 77) TCTCGTCTCCTGTCCC 1 chr16:30526882-30527382 ( 55) TCTCGCTCCCTCCCCT 1 chr6:157323318-157323818 ( 55) TTCCGCTACCGCCTCC 1 chr17:68511868-68512368 ( 26) TTCCTCCGCCTGCTCT 1 chr16:30378350-30378850 ( 57) CACCTCTTCGTCTTTC 1 chr21:37072495-37072995 ( 40) CCCTGCCCTATCCTCC 1 chr19:39390701-39391201 ( 10) CCCCTCTGCGTCCCCC 1 chr6:24774896-24775396 ( 25) TCCTGCCGCCTCTTGC 1 chr6:87322344-87322844 ( 5) GCCCTCCGCCGCTCTC 1 chr17:18087643-18088143 ( 78) GTTCTCTTTGGCTTCC 1 chr20:44210257-44210757 ( 17) TCCCCTTCCCGCCTTC 1 chr11:10931252-10931752 ( 51) CTCCGTCCCGGCCTCC 1 chr19:14496011-14496511 ( 51) TCCCTCCGCCTCGCCC 1 chr6:16759816-16760316 ( 62) CCCCTTCCCTGCCCCC 1 chr17:50560473-50560973 ( 54) CCTCGCCGCCGCTTTC 1 chr19:38336503-38337003 ( 85) TCCTTATTCCGCCCCC 1 chr9:129110777-129111277 ( 17) TCTCTCCCCTGTCCCC 1 chr12:49130967-49131467 ( 81) GCTTTTCCCTGCTTCC 1 chr16:690211-690711 ( 23) TTCTTACCCATCCCTC 1 chr21:41766760-41767260 ( 63) TCCCGCCGTCGCCCTC 1 chr13:111153240-11115374 ( 17) CACCGCCGCCTCCTCC 1 chr19:17337061-17337561 ( 34) CTCTGTCCTTTCTTCC 1 chr7:97117342-97117842 ( 81) TCTTTCGTCTGCCTTC 1 chr21:43857406-43857906 ( 50) GCCCACCTCAGCCTCC 1 chr1:206612159-206612659 ( 3) TTCTGTGCTCTCTTCC 1 chrX:104156557-104157057 ( 5) CCCCTACTCCTCATCC 1 chr7:155328565-155329065 ( 34) TCTCTCCCTCTCCCCA 1 chr22:42188800-42189300 ( 11) TTGTTCCCCTTCCCCC 1 chr12:28190407-28190907 ( 14) CCCCTCTCTCGCTCTC 1 chr22:38681725-38682225 ( 22) CCTCCTTTCCGCTTCC 1 chr12:27710712-27711212 ( 50) GTCTGTCTCGTCTTCT 1 chr20:37095802-37096302 ( 54) GTCTGCCTCCGCTTTT 1 chr1:167714407-167714907 ( 54) TCTCACCTCGTGTTCC 1 chr12:1202943-1203443 ( 23) TTGTGCCTCAGCCTCC 1 chr6:85593463-85593963 ( 24) TTCTGCCCCATCGTCC 1 chr20:58650974-58651474 ( 25) TTCCTGTCCGTCCCTC 1 chr5:38556672-38557172 ( 26) TCTCCCCTGCGCTTCC 1 chr1:230868091-230868591 ( 75) CTTCTCCTTGTCCTGC 1 chr13:49936023-49936523 ( 78) CTCCGTCTCCTGCCCC 1 chr12:109573064-10957356 ( 82) CCTGTCCCCGTCTTCC 1 chr21:42973818-42974318 ( 26) TTCCTCCCCAGGCTCT 1 chr5:176388756-176389256 ( 69) CTTCTCTACTTCCTTC 1 chr14:30559083-30559583 ( 28) GTCCTGCTTCTCTCTC 1 chr6:85679050-85679550 ( 21) TTCCGCTTTTTCACCC 1 chr17:74430752-74431252 ( 77) TCCCTCCGCGTCTCCA 1 chr3:112561472-112561972 ( 13) CCCCGCCCCCTCGTCC 1 chr9:128947576-128948076 ( 33) TTCCCGCCCCGCTTCC 1 chr13:110965221-11096572 ( 5) TCCTGACTCATTCTCC 1 chr11:47578740-47579240 ( 27) CTCCGCTTCCGGCTCC 1 chr19:33373103-33373603 ( 41) TTTCGCCGCGTCCCTT 1 chr4:2009184-2009684 ( 33) GCTCTTCGCTTTTTCC 1 chr2:37925247-37925747 ( 44) TATTTCCGCTTCCCTC 1 chr20:63657984-63658484 ( 43) GCTCTTCGGCTCCTCC 1 chr1:10854793-10855293 ( 36) TATCATCCTCTCTTCC 1 chrX:41084836-41085336 ( 76) TGTCTTCCCCTCCCCC 1 chr12:124914536-12491503 ( 6) TTTCCTCGCCTGTTCC 1 chr11:57741077-57741577 ( 12) CTCCGCCCCTTCCTGC 1 chr2:197499607-197500107 ( 71) CCCTCCCTCCGCCTCT 1 chr21:36980450-36980950 ( 20) TCCTGGCCCCGCTCCC 1 chr19:40420974-40421474 ( 38) CCCCTGCGCCTCTCTC 1 chr10:75111529-75112029 ( 76) TCCCTCGGCAGCCCCC 1 chr1:183471821-183472321 ( 48) CCCCTTCTTATCACTC 1 chr1:53220252-53220752 ( 29) TCGCTTCATCTCCTCC 1 chr19:40920894-40921394 ( 52) GTTTATCTTATCCTCC 1 chr6:85642924-85643424 ( 15) TCTTATTCCCGCCCCC 1 chr5:181215878-181216378 ( 16) TCGTGCCCCAGCCTCC 1 chr12:63419081-63419581 ( 68) TACCTGCTCATTCTCC 1 chr20:45934618-45935118 ( 62) CCCCTCCGGCGCTTTC 1 chr22:19432258-19432758 ( 78) TACCCTCGCCGCTTCC 1 chr10:110497337-11049783 ( 57) TTCCTCCTCGGTCCGC 1 chr12:89709711-89710211 ( 42) GCTCGCCCTCGCCCTC 1 chrX:72276898-72277398 ( 45) TCCGCCTCCATCCTCC 1 chr15:77419803-77420303 ( 42) GTCCGTCCCGTCCCCT 1 chr10:102713943-10271444 ( 73) TCCCCCTCCCGTCCCC 1 chr19:44500175-44500675 ( 37) TTCGGTCCCCTCTCCT 1 chr7:100705380-100705880 ( 71) TTCCCCCTCGGTCCTC 1 chr5:177086847-177087347 ( 80) CCCCGCCGCCTCTCGC 1 chr15:72231019-72231519 ( 22) TCCCTCCGCCGCCCCG 1 chr17:82065643-82066143 ( 45) TCTCGTCGCCGGTCCC 1 chr19:44212430-44212930 ( 74) TCCCGCCCTCGGCCTC 1 chr21:29052239-29052739 ( 62) GTCTTTCCCATCCTTA 1 chr7:108569869-108570369 ( 37) CCCGGCCTCGTCCCTC 1 chr15:75201730-75202230 ( 72) CTCCGCGTCCGCATCC 1 chr19:58327057-58327557 ( 35) GTCCGTCACATCCTCT 1 chr6:7541539-7542039 ( 65) TCCCGCCCGGTTCCCC 1 chr5:150000331-150000831 ( 9) TTCCTCCTCCGCCCGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 9.83962 E= 8.2e-034 -1387 -41 -94 172 -217 86 -558 105 -1387 110 -326 63 -1387 118 -326 41 -195 -188 0 160 -276 108 -278 49 -1387 122 -278 20 -276 17 -83 126 -1387 130 -278 -11 -23 79 -78 -76 -1387 -1387 25 178 -1387 141 -226 -106 -217 89 -400 94 -1387 30 -1387 175 -1387 112 -278 53 -317 143 -458 -76 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 150 E= 8.2e-034 0.000000 0.240000 0.166667 0.593333 0.040000 0.580000 0.006667 0.373333 0.000000 0.686667 0.033333 0.280000 0.000000 0.726667 0.033333 0.240000 0.046667 0.086667 0.320000 0.546667 0.026667 0.673333 0.046667 0.253333 0.000000 0.746667 0.046667 0.206667 0.026667 0.360000 0.180000 0.433333 0.000000 0.786667 0.046667 0.166667 0.153333 0.553333 0.186667 0.106667 0.000000 0.000000 0.380000 0.620000 0.000000 0.846667 0.066667 0.086667 0.040000 0.593333 0.020000 0.346667 0.000000 0.393333 0.000000 0.606667 0.000000 0.693333 0.046667 0.260000 0.020000 0.860000 0.013333 0.106667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCCKCCYCCKCYYCC MEME-2 regular expression -------------------------------------------------------------------------------- [TC][CT][CT][CT][TG][CT][CT][TC]CC[TG]C[CT][TC][CT]C -------------------------------------------------------------------------------- Time 679.99 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 width = 31 sites = 8 llr = 268 E-value = 7.7e-030 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A 8a8:4:::1::9::a:a:1:5:16:::a:18 pos.-specific C :::::1a:::::3::a:::a:111:8a:68: probability G 3:36:8::9a9::::::a9:5:8:a:::::3 matrix T :::461:a::118a:::::::9:3:3::41: bits 2.5 * * ** * * 2.2 * * ** * * 2.0 * * * ** * * 1.7 * ** * * ***** * * * ** Relative 1.5 *** * ** * ******* * * * ** * Entropy 1.2 *** * ************** * * ** * (48.4 bits) 1.0 ***** **************** ****** * 0.7 ******************************* 0.5 ******************************* 0.2 ******************************* 0.0 ------------------------------- Multilevel AAAGTGCTGGGATTACAGGCATGAGCCACCA consensus G GTA C G T T T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr12:112387664-11238816 - 70 2.18e-18 . AAAGTGCTGGGATTACAGGCATGAGCCATAA CTTTTTGTTT chr21:43857406-43857906 - 18 6.69e-18 TCAGCCTCCC AAAGTGCTGGGATTACAGGCATGAGTCACTA CACCCGACAG chr19:40403805-40404305 + 59 1.42e-17 tcggcctccc aaagtgctgggattacaggcgtgagccaccg cgcccggccA chr1:28373345-28373845 + 5 9.78e-17 tccc aaagttctgggattacaggcgtcagccatca cgcctggccC chr5:181215878-181216378 + 33 6.30e-16 ccagcctccc aagtagctgggattacaggcgtgtgccaccg cgcccagcta chr1:12539682-12540182 + 2 2.26e-15 c aaagtgctagttttacagacatgagtcacca tgcctggaga chr12:1202943-1203443 + 40 9.79e-15 tcagcctcct gagtacctgggactacaggcgtgtgccacca cgcctggcta chr17:59291798-59292298 + 60 1.66e-14 tcagcctcct gaatagctgggactacaggcacacgccatca tgcccagcta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:112387664-11238816 2.2e-18 69_[-3] chr21:43857406-43857906 6.7e-18 17_[-3]_52 chr19:40403805-40404305 1.4e-17 58_[+3]_11 chr1:28373345-28373845 9.8e-17 4_[+3]_65 chr5:181215878-181216378 6.3e-16 32_[+3]_37 chr1:12539682-12540182 2.3e-15 1_[+3]_68 chr12:1202943-1203443 9.8e-15 39_[+3]_30 chr17:59291798-59292298 1.7e-14 59_[+3]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAKWGCTGGGATTACAGGCRTGAGCCAYCA width=31 seqs=8 chr12:112387664-11238816 ( 70) AAAGTGCTGGGATTACAGGCATGAGCCATAA 1 chr21:43857406-43857906 ( 18) AAAGTGCTGGGATTACAGGCATGAGTCACTA 1 chr19:40403805-40404305 ( 59) AAAGTGCTGGGATTACAGGCGTGAGCCACCG 1 chr1:28373345-28373845 ( 5) AAAGTTCTGGGATTACAGGCGTCAGCCATCA 1 chr5:181215878-181216378 ( 33) AAGTAGCTGGGATTACAGGCGTGTGCCACCG 1 chr1:12539682-12540182 ( 2) AAAGTGCTAGTTTTACAGACATGAGTCACCA 1 chr12:1202943-1203443 ( 40) GAGTACCTGGGACTACAGGCGTGTGCCACCA 1 chr17:59291798-59292298 ( 60) GAATAGCTGGGACTACAGGCACACGCCATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 12.3578 E= 7.7e-030 205 -965 -35 -965 247 -965 -965 -965 205 -965 -35 -965 -965 -965 97 105 105 -965 -965 179 -965 -135 123 -53 -965 164 -965 -965 -965 -965 -965 247 -53 -965 145 -965 -965 -965 164 -965 -965 -965 145 -53 228 -965 -965 -53 -965 -35 -965 205 -965 -965 -965 247 247 -965 -965 -965 -965 164 -965 -965 247 -965 -965 -965 -965 -965 164 -965 -53 -965 145 -965 -965 164 -965 -965 147 -965 65 -965 -965 -135 -965 228 -53 -135 123 -965 179 -135 -965 47 -965 -965 164 -965 -965 123 -965 47 -965 164 -965 -965 247 -965 -965 -965 -965 97 -965 105 -53 123 -965 -53 205 -965 -35 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 8 E= 7.7e-030 0.750000 0.000000 0.250000 0.000000 1.000000 0.000000 0.000000 0.000000 0.750000 0.000000 0.250000 0.000000 0.000000 0.000000 0.625000 0.375000 0.375000 0.000000 0.000000 0.625000 0.000000 0.125000 0.750000 0.125000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.125000 0.000000 0.875000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.875000 0.125000 0.875000 0.000000 0.000000 0.125000 0.000000 0.250000 0.000000 0.750000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.125000 0.000000 0.875000 0.000000 0.000000 1.000000 0.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.125000 0.000000 0.875000 0.125000 0.125000 0.750000 0.000000 0.625000 0.125000 0.000000 0.250000 0.000000 0.000000 1.000000 0.000000 0.000000 0.750000 0.000000 0.250000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.625000 0.000000 0.375000 0.125000 0.750000 0.000000 0.125000 0.750000 0.000000 0.250000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAKWGCTGGGATTACAGGCRTGAGCCAYCA MEME-3 regular expression -------------------------------------------------------------------------------- [AG]A[AG][GT][TA]GCTGGGA[TC]TACAGGC[AG]TG[AT]G[CT]CA[CT]C[AG] -------------------------------------------------------------------------------- Time 974.80 secs. ******************************************************************************** ******************************************************************************** MOTIF YACMYRCTCCACHCWGASWCAY MEME-4 width = 22 sites = 15 llr = 250 E-value = 1.4e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 Description -------------------------------------------------------------------------------- Simplified A :a:5:4113:a:4:31913191 pos.-specific C 5:94318178:649:2152914 probability G 1:1:14:::::1:::6:3:::1 matrix T 5::16118:2:32171:15:14 bits 2.5 * * 2.2 * * 2.0 * * * 1.7 * * * * Relative 1.5 * * * * * * Entropy 1.2 * * * ** * ** (24.0 bits) 1.0 **** ***** ** * ** 0.7 ***** ***** *** * *** 0.5 ***** ********* * **** 0.2 ********************** 0.0 ---------------------- Multilevel CACATACTCCACACTGACTCAC consensus T CCG AT TC AC GA T sequence T C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr6:29845302-29845802 + 11 5.81e-12 tcattctggt tacctgctccaccctgactcat tccagtcacc chr5:115928858-115929358 - 23 5.81e-12 TCATTCCGAT TACCTGCTCCACCCTGACTCAT TCCGATTACC chr12:63419081-63419581 + 12 7.03e-12 tcattccgat tacctgctccactctgactcat tctgattgcc chr13:110965221-11096572 + 39 1.85e-11 tcattctgat tacttactccaccctgactcat tttccaccct chr1:236097028-236097528 - 36 4.05e-10 CACCCCTGGC CACCTGCTCCATTCTGAGTCAC CCCTGGCCGC chr21:45591078-45591578 + 58 1.72e-09 tggacaccca cacacactccacatagacacac acaacactcc chr19:33249578-33250078 + 60 8.70e-09 acaccacatg cacacaccacacacagacacac agatacacac chr8:6648852-6649352 - 29 1.25e-08 CACCCTTAGT CACCTGTTCTATCCTTAGTCAT CCTTAGTCAC chr1:235078182-235078682 - 39 2.46e-08 CACATATGCA CACACACAACACACACATACAA CACACACAAC chr8:99012910-99013410 + 59 5.74e-08 ACGCGCAGAG TAGCTTCTCCAGCCTGAGAAAT CCGGTCCGGC chr19:682063-682563 - 3 1.07e-07 TCACCCAGGC TAGACCCTCCATACTCACCCAG GC chr21:6565296-6565796 + 65 1.58e-07 ctccacactc cacacactccacacacaccaca cactccacac chr12:130764516-13076501 - 78 1.90e-07 T GACATCATCCACACTGCATCAC CAACACCATG chr11:35526416-35526916 + 63 2.56e-07 agcttaggcc cacaggctatagtcttagccac taggctataG chrUn_KI270467v1:2903-34 - 72 3.79e-07 TATACTG TACATAAAATATCCAAATACTC AAAATATATA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:29845302-29845802 5.8e-12 10_[+4]_68 chr5:115928858-115929358 5.8e-12 22_[-4]_56 chr12:63419081-63419581 7e-12 11_[+4]_67 chr13:110965221-11096572 1.8e-11 38_[+4]_40 chr1:236097028-236097528 4e-10 35_[-4]_43 chr21:45591078-45591578 1.7e-09 57_[+4]_21 chr19:33249578-33250078 8.7e-09 59_[+4]_19 chr8:6648852-6649352 1.2e-08 28_[-4]_50 chr1:235078182-235078682 2.5e-08 38_[-4]_40 chr8:99012910-99013410 5.7e-08 58_[+4]_20 chr19:682063-682563 1.1e-07 2_[-4]_76 chr21:6565296-6565796 1.6e-07 64_[+4]_14 chr12:130764516-13076501 1.9e-07 77_[-4]_1 chr11:35526416-35526916 2.6e-07 62_[+4]_16 chrUn_KI270467v1:2903-34 3.8e-07 71_[-4]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YACMYRCTCCACHCWGASWCAY width=22 seqs=15 chr6:29845302-29845802 ( 11) TACCTGCTCCACCCTGACTCAT 1 chr5:115928858-115929358 ( 23) TACCTGCTCCACCCTGACTCAT 1 chr12:63419081-63419581 ( 12) TACCTGCTCCACTCTGACTCAT 1 chr13:110965221-11096572 ( 39) TACTTACTCCACCCTGACTCAT 1 chr1:236097028-236097528 ( 36) CACCTGCTCCATTCTGAGTCAC 1 chr21:45591078-45591578 ( 58) CACACACTCCACATAGACACAC 1 chr19:33249578-33250078 ( 60) CACACACCACACACAGACACAC 1 chr8:6648852-6649352 ( 29) CACCTGTTCTATCCTTAGTCAT 1 chr1:235078182-235078682 ( 39) CACACACAACACACACATACAA 1 chr8:99012910-99013410 ( 59) TAGCTTCTCCAGCCTGAGAAAT 1 chr19:682063-682563 ( 3) TAGACCCTCCATACTCACCCAG 1 chr21:6565296-6565796 ( 65) CACACACTCCACACACACCACA 1 chr12:130764516-13076501 ( 78) GACATCATCCACACTGCATCAC 1 chr11:35526416-35526916 ( 63) CACAGGCTATAGTCTTAGCCAC 1 chrUn_KI270467v1:2903-34 ( 72) TACATAAAATATCCAAATACTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 12.2997 E= 1.4e-005 -1055 55 -226 137 247 -1055 -1055 -1055 -1055 144 -126 -1055 156 32 -1055 -143 -1055 6 -226 173 115 -126 32 -143 -44 132 -1055 -143 -44 -226 -1055 215 56 120 -1055 -1055 -1055 132 -1055 15 247 -1055 -1055 -1055 -1055 91 -126 56 115 32 -1055 15 -1055 155 -1055 -143 89 -1055 -1055 189 -143 -68 91 -44 237 -226 -1055 -1055 -143 74 -26 -44 89 -68 -1055 137 -44 144 -1055 -1055 226 -226 -1055 -143 -44 32 -226 115 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 15 E= 1.4e-005 0.000000 0.466667 0.066667 0.466667 1.000000 0.000000 0.000000 0.000000 0.000000 0.866667 0.133333 0.000000 0.533333 0.400000 0.000000 0.066667 0.000000 0.333333 0.066667 0.600000 0.400000 0.133333 0.400000 0.066667 0.133333 0.800000 0.000000 0.066667 0.133333 0.066667 0.000000 0.800000 0.266667 0.733333 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 1.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.133333 0.266667 0.400000 0.400000 0.000000 0.200000 0.000000 0.933333 0.000000 0.066667 0.333333 0.000000 0.000000 0.666667 0.066667 0.200000 0.600000 0.133333 0.933333 0.066667 0.000000 0.000000 0.066667 0.533333 0.266667 0.133333 0.333333 0.200000 0.000000 0.466667 0.133333 0.866667 0.000000 0.000000 0.866667 0.066667 0.000000 0.066667 0.133333 0.400000 0.066667 0.400000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YACMYRCTCCACHCWGASWCAY MEME-4 regular expression -------------------------------------------------------------------------------- [CT]AC[AC][TC][AG]CT[CA][CT]A[CT][ACT]C[TA][GC]A[CG][TAC]CA[CT] -------------------------------------------------------------------------------- Time 1268.00 secs. ******************************************************************************** ******************************************************************************** MOTIF AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 width = 49 sites = 4 llr = 234 E-value = 3.0e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 Description -------------------------------------------------------------------------------- Simplified A aa::3388::a88:a:3:::::::::a:a:3::3::a::855:a:a835 pos.-specific C :::::::::8:::a:5::aa::a::a:a::::a::8::::::::3:::: probability G ::aa8833a::33:::8:::::::::::::8a:8a::aa:55a:8:38: matrix T :::::::::3:::::5:a::aa:aa::::a:::::3:::3::::::::5 bits 2.5 ** * * * ** ** * ** * * * 2.2 ** * * * ** ** * ** * * * 2.0 ** * * * ** ** * ** * * * 1.7 **** * * ** ************* ** * **** ** * Relative 1.5 **** *** ***** ************* ** * **** ** ** * Entropy 1.2 **** *** ***** ************* ** * **** ** ** * (84.5 bits) 1.0 ******************************************** **** 0.7 ************************************************* 0.5 ************************************************* 0.2 ************************************************* 0.0 ------------------------------------------------- Multilevel AAGGGGAAGCAAACACGTCCTTCTTCACATGGCGGCAGGAAAGAGAAGA consensus AAGG T GG TA A A T TGG C GAT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------------------------- chr16:15982144-15982644 + 42 3.53e-29 atcatggtag aaggggaagcaaacacgtccttcttcacatggcggcaggaaggagaagt gctgagcaaa chr14:90526500-90527000 - 42 8.53e-28 ATCATGGAGG AAGGGGAGGCAAACATGTCCTTCTTCACATGGCAGCAGGAAGGAGAAGT GCCGTGCAAA chr19:2378614-2379114 + 12 1.92e-27 atcatggcgg aaggaggagcaaacatgtccttcttcacatggcggtaggagagagaaga atgaaagccc chr5:124987722-124988222 - 45 4.90e-25 ATAGTGC AAGGGAAAGTAGGCACATCCTTCTTCACATAGCGGCAGGTGAGACAGAA GTTCCGAGCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:15982144-15982644 3.5e-29 41_[+5]_10 chr14:90526500-90527000 8.5e-28 41_[-5]_10 chr19:2378614-2379114 1.9e-27 11_[+5]_40 chr5:124987722-124988222 4.9e-25 44_[-5]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW width=49 seqs=4 chr16:15982144-15982644 ( 42) AAGGGGAAGCAAACACGTCCTTCTTCACATGGCGGCAGGAAGGAGAAGT 1 chr14:90526500-90527000 ( 42) AAGGGGAGGCAAACATGTCCTTCTTCACATGGCAGCAGGAAGGAGAAGT 1 chr19:2378614-2379114 ( 12) AAGGAGGAGCAAACATGTCCTTCTTCACATGGCGGTAGGAGAGAGAAGA 1 chr5:124987722-124988222 ( 45) AAGGGAAAGTAGGCACATCCTTCTTCACATAGCGGCAGGTGAGACAGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 49 n= 31200 bayes= 11.1631 E= 3.0e-017 247 -865 -865 -865 247 -865 -865 -865 -865 -865 164 -865 -865 -865 164 -865 47 -865 123 -865 47 -865 123 -865 205 -865 -35 -865 205 -865 -35 -865 -865 -865 164 -865 -865 123 -865 47 247 -865 -865 -865 205 -865 -35 -865 205 -865 -35 -865 -865 164 -865 -865 247 -865 -865 -865 -865 64 -865 147 47 -865 123 -865 -865 -865 -865 247 -865 164 -865 -865 -865 164 -865 -865 -865 -865 -865 247 -865 -865 -865 247 -865 164 -865 -865 -865 -865 -865 247 -865 -865 -865 247 -865 164 -865 -865 247 -865 -865 -865 -865 164 -865 -865 247 -865 -865 -865 -865 -865 -865 247 47 -865 123 -865 -865 -865 164 -865 -865 164 -865 -865 47 -865 123 -865 -865 -865 164 -865 -865 123 -865 47 247 -865 -865 -865 -865 -865 164 -865 -865 -865 164 -865 205 -865 -865 47 147 -865 64 -865 147 -865 64 -865 -865 -865 164 -865 247 -865 -865 -865 -865 -35 123 -865 247 -865 -865 -865 205 -865 -35 -865 47 -865 123 -865 147 -865 -865 147 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 49 nsites= 4 E= 3.0e-017 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.250000 0.000000 0.750000 0.000000 0.250000 0.000000 0.750000 0.000000 0.750000 0.000000 0.250000 0.000000 0.750000 0.000000 0.250000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.750000 0.000000 0.250000 1.000000 0.000000 0.000000 0.000000 0.750000 0.000000 0.250000 0.000000 0.750000 0.000000 0.250000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.500000 0.250000 0.000000 0.750000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.250000 0.000000 0.750000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.250000 0.000000 0.750000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.750000 0.000000 0.250000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.750000 0.000000 0.000000 0.250000 0.500000 0.000000 0.500000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.250000 0.750000 0.000000 1.000000 0.000000 0.000000 0.000000 0.750000 0.000000 0.250000 0.000000 0.250000 0.000000 0.750000 0.000000 0.500000 0.000000 0.000000 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGGGGAAGCAAACAYGTCCTTCTTCACATGGCGGCAGGARRGAGAAGW MEME-5 regular expression -------------------------------------------------------------------------------- AAGG[GA][GA][AG][AG]G[CT]A[AG][AG]CA[CT][GA]TCCTTCTTCACAT[GA]GC[GA]G[CT]AGG[AT][AG][AG]GA[GC]A[AG][GA][AT] -------------------------------------------------------------------------------- Time 1556.30 secs. ******************************************************************************** ******************************************************************************** MOTIF AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 width = 29 sites = 10 llr = 237 E-value = 1.2e-011 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 Description -------------------------------------------------------------------------------- Simplified A a:112131::12a9:::1::7::127423 pos.-specific C :1:7:1:3817:::82783::7a:5:::1 probability G :8611871:::8::22:::93::::367: matrix T :1317::5292::1:63171:3:93::16 bits 2.5 * * 2.2 * * 2.0 * * ** * 1.7 * * ** ** Relative 1.5 * * ** ** Entropy 1.2 * * * ** *** ** * (34.2 bits) 1.0 * * * ** **** ******** ** * 0.7 *** *** **************** **** 0.5 ***************************** 0.2 ***************************** 0.0 ----------------------------- Multilevel AGGCTGGTCTCGAACTCCTGACCTCAGGT consensus T A ACT TA GCT C GT TGAAA sequence G A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ----------------------------- chr19:39033050-39033550 - 3 5.40e-15 CATGTTGGCC AGGCTGGTCTCGAACTTCTGACCTCAAGC GA chr20:35616573-35617073 + 66 7.39e-15 cgtgttaatc aggctggcctcgaactcccgacctcaggt gatccg chr21:43857406-43857906 - 71 5.03e-14 C ATACTGATCTTGAACTCCTGACCTCAGGT GATCTGCCCA chr7:139339841-139340341 + 51 1.01e-12 tgtgttggtc aggctggtttcaaacccccgacctaagat gatccgcccg chr1:150876800-150877300 - 43 1.54e-12 CATGTTGGCC AGGCTGGTTTCGAACCCCTGGCCACAGGT GATCCGGCCG chr22:37844516-37845016 + 63 5.92e-12 catgttggcc aggatggtctcgatctcttgatctcgaga tgtgccggc chr17:59291798-59292298 + 9 7.08e-12 catagttc actgtagcctcaaactcctgatcttaagt gatcctccca chr17:75784974-75785474 - 71 1.26e-10 C AGTTAGGCCTCGAAGGCCTGGCCTAGGGA GAGTGCACTC chr16:28863109-28863609 - 27 1.17e-09 CCCTGCGGGG AGGCGGAGCCTGAACTTACGACCTTGGTT TATCTGAGGA chr6:82260134-82260634 - 13 1.22e-09 ATCAAATTCA AGTCACAACTAGAAGGTCTTGTCTTAAAA AAGGTGAGGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:39033050-39033550 5.4e-15 2_[-6]_69 chr20:35616573-35617073 7.4e-15 65_[+6]_6 chr21:43857406-43857906 5e-14 70_[-6]_1 chr7:139339841-139340341 1e-12 50_[+6]_21 chr1:150876800-150877300 1.5e-12 42_[-6]_29 chr22:37844516-37845016 5.9e-12 62_[+6]_9 chr17:59291798-59292298 7.1e-12 8_[+6]_63 chr17:75784974-75785474 1.3e-10 70_[-6]_1 chr16:28863109-28863609 1.2e-09 26_[-6]_45 chr6:82260134-82260634 1.2e-09 12_[-6]_59 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGKCTGGYCTCGAACTCCTGACCTYARGW width=29 seqs=10 chr19:39033050-39033550 ( 3) AGGCTGGTCTCGAACTTCTGACCTCAAGC 1 chr20:35616573-35617073 ( 66) AGGCTGGCCTCGAACTCCCGACCTCAGGT 1 chr21:43857406-43857906 ( 71) ATACTGATCTTGAACTCCTGACCTCAGGT 1 chr7:139339841-139340341 ( 51) AGGCTGGTTTCAAACCCCCGACCTAAGAT 1 chr1:150876800-150877300 ( 43) AGGCTGGTTTCGAACCCCTGGCCACAGGT 1 chr22:37844516-37845016 ( 63) AGGATGGTCTCGATCTCTTGATCTCGAGA 1 chr17:59291798-59292298 ( 9) ACTGTAGCCTCAAACTCCTGATCTTAAGT 1 chr17:75784974-75785474 ( 71) AGTTAGGCCTCGAAGGCCTGGCCTAGGGA 1 chr16:28863109-28863609 ( 27) AGGCGGAGCCTGAACTTACGACCTTGGTT 1 chr6:82260134-82260634 ( 13) AGTCACAACTAGAAGGTCTTGTCTTAAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 29 n= 43200 bayes= 12.3281 E= 1.2e-011 247 -997 -997 -997 -997 -167 132 -85 -85 -997 91 73 -85 113 -167 -85 15 -997 -167 196 -85 -167 132 -997 73 -997 113 -997 -85 -9 -167 147 -997 132 -997 15 -997 -167 -997 232 -85 113 -997 15 15 -997 132 -997 247 -997 -997 -997 232 -997 -997 -85 -997 132 -68 -997 -997 -68 -68 173 -997 113 -997 73 -85 132 -997 -85 -997 -9 -997 196 -997 -997 149 -85 196 -997 -9 -997 -997 113 -997 73 -997 164 -997 -997 -85 -997 -997 232 15 65 -997 73 196 -997 -9 -997 115 -997 91 -997 15 -997 113 -85 73 -167 -997 173 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 29 nsites= 10 E= 1.2e-011 1.000000 0.000000 0.000000 0.000000 0.000000 0.100000 0.800000 0.100000 0.100000 0.000000 0.600000 0.300000 0.100000 0.700000 0.100000 0.100000 0.200000 0.000000 0.100000 0.700000 0.100000 0.100000 0.800000 0.000000 0.300000 0.000000 0.700000 0.000000 0.100000 0.300000 0.100000 0.500000 0.000000 0.800000 0.000000 0.200000 0.000000 0.100000 0.000000 0.900000 0.100000 0.700000 0.000000 0.200000 0.200000 0.000000 0.800000 0.000000 1.000000 0.000000 0.000000 0.000000 0.900000 0.000000 0.000000 0.100000 0.000000 0.800000 0.200000 0.000000 0.000000 0.200000 0.200000 0.600000 0.000000 0.700000 0.000000 0.300000 0.100000 0.800000 0.000000 0.100000 0.000000 0.300000 0.000000 0.700000 0.000000 0.000000 0.900000 0.100000 0.700000 0.000000 0.300000 0.000000 0.000000 0.700000 0.000000 0.300000 0.000000 1.000000 0.000000 0.000000 0.100000 0.000000 0.000000 0.900000 0.200000 0.500000 0.000000 0.300000 0.700000 0.000000 0.300000 0.000000 0.400000 0.000000 0.600000 0.000000 0.200000 0.000000 0.700000 0.100000 0.300000 0.100000 0.000000 0.600000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGKCTGGYCTCGAACTCCTGACCTYARGW MEME-6 regular expression -------------------------------------------------------------------------------- AG[GT]C[TA]G[GA][TC][CT]T[CT][GA]AA[CG][TCG][CT]C[TC]G[AG][CT]CT[CTA][AG][GA][GA][TA] -------------------------------------------------------------------------------- Time 1843.72 secs. ******************************************************************************** ******************************************************************************** MOTIF KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 width = 30 sites = 10 llr = 236 E-value = 1.2e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 Description -------------------------------------------------------------------------------- Simplified A :732::134:1114:47:1:2:4879::1: pos.-specific C 11:79:9232::75551172:::2:::::1 probability G 61711::43214::1:2:::816:::2899 matrix T 31:::a:1:6852141:928:9::3182:: bits 2.5 * 2.2 * 2.0 * * * * 1.7 * * * * Relative 1.5 * * * * * **** Entropy 1.2 *** * * * * **** ** (34.0 bits) 1.0 ** *** * ** *********** 0.7 ****** ***** *************** 0.5 ******* ********************** 0.2 ****************************** 0.0 ------------------------------ Multilevel GAGCCTCGATTTCCCCATCTGTGAAATGGG consensus T AA ACC GTATAG TCA ACT GT sequence CGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------ chr15:73699645-73700145 + 37 1.46e-14 ttactgttct tagcctccatttccttgtctgtaaaatggg aacatgagtg chr15:74223036-74223536 - 12 1.14e-13 TTGCTTTCTA GAGCCTCTCTTTCCCCACCTGTGAAATGGG CCAGTGACAA chr10:95561543-95562043 + 40 1.42e-12 tttaactcct gggcctcagtttacccatctgtaaaatggc ataatagtcc chr1:148522491-148522991 + 20 1.73e-12 ccaaatgtgg gaaactcgactgcataatttgtgatagtgg ggggctgcgt chr11:78188207-78188707 - 39 2.55e-12 TAATCTATCC CAGCCTCGCCATTCCCATCTGTGAAATGGG GATGGCATCG chr2:11743847-11744347 - 21 3.73e-12 CCTGATTCTA GAGGCTCAGTTTCACAATCCAGGAAATGGG CTGCAGGTGC chr1:145280975-145281475 + 51 1.00e-11 ccaagtgtgg gaaactcgagtgcataatttgtgatagtag ggaactacgt chr7:44796017-44796517 + 63 1.09e-11 AGGCCTGCGT TCGCCTCAGTTGCCCCCTCTGTGCAATGGG GAGACGCG chr2:241149782-241150282 - 30 6.83e-11 TGACCTCTGC GAGCCTCGCTGGCTGCGTCTGTACAATGGG CCGAACGGCA chrUn_KI270467v1:2903-34 + 3 5.60e-09 at ttacgtacagtatataatacataatttggg tactttgata -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:73699645-73700145 1.5e-14 36_[+7]_34 chr15:74223036-74223536 1.1e-13 11_[-7]_59 chr10:95561543-95562043 1.4e-12 39_[+7]_31 chr1:148522491-148522991 1.7e-12 19_[+7]_51 chr11:78188207-78188707 2.6e-12 38_[-7]_32 chr2:11743847-11744347 3.7e-12 20_[-7]_50 chr1:145280975-145281475 1e-11 50_[+7]_20 chr7:44796017-44796517 1.1e-11 62_[+7]_8 chr2:241149782-241150282 6.8e-11 29_[-7]_41 chrUn_KI270467v1:2903-34 5.6e-09 2_[+7]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KAGCCTCVVTTKCMYMATCTGTRAAATGGG width=30 seqs=10 chr15:73699645-73700145 ( 37) TAGCCTCCATTTCCTTGTCTGTAAAATGGG 1 chr15:74223036-74223536 ( 12) GAGCCTCTCTTTCCCCACCTGTGAAATGGG 1 chr10:95561543-95562043 ( 40) GGGCCTCAGTTTACCCATCTGTAAAATGGC 1 chr1:148522491-148522991 ( 20) GAAACTCGACTGCATAATTTGTGATAGTGG 1 chr11:78188207-78188707 ( 39) CAGCCTCGCCATTCCCATCTGTGAAATGGG 1 chr2:11743847-11744347 ( 21) GAGGCTCAGTTTCACAATCCAGGAAATGGG 1 chr1:145280975-145281475 ( 51) GAAACTCGAGTGCATAATTTGTGATAGTAG 1 chr7:44796017-44796517 ( 63) TCGCCTCAGTTGCCCCCTCTGTGCAATGGG 1 chr2:241149782-241150282 ( 30) GAGCCTCGCTGGCTGCGTCTGTACAATGGG 1 chrUn_KI270467v1:2903-34 ( 3) TTACGTACAGTATATAATACATAATTTGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 30 n= 42600 bayes= 12.3079 E= 1.2e-009 -997 -167 91 73 196 -167 -167 -85 73 -997 113 -997 15 113 -167 -997 -997 149 -167 -997 -997 -997 -997 247 -85 149 -997 -997 73 -68 32 -85 115 -9 -9 -997 -997 -68 -68 173 -85 -997 -167 215 -85 -997 32 147 -85 113 -997 15 115 65 -997 -85 -997 65 -167 115 115 65 -997 -85 196 -167 -68 -997 -997 -167 -997 232 -85 113 -997 15 -997 -68 -997 215 15 -997 132 -997 -997 -997 -167 232 115 -997 91 -997 215 -68 -997 -997 196 -997 -997 73 232 -997 -997 -85 -997 -997 -68 215 -997 -997 132 15 -85 -997 149 -997 -997 -167 149 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 30 nsites= 10 E= 1.2e-009 0.000000 0.100000 0.600000 0.300000 0.700000 0.100000 0.100000 0.100000 0.300000 0.000000 0.700000 0.000000 0.200000 0.700000 0.100000 0.000000 0.000000 0.900000 0.100000 0.000000 0.000000 0.000000 0.000000 1.000000 0.100000 0.900000 0.000000 0.000000 0.300000 0.200000 0.400000 0.100000 0.400000 0.300000 0.300000 0.000000 0.000000 0.200000 0.200000 0.600000 0.100000 0.000000 0.100000 0.800000 0.100000 0.000000 0.400000 0.500000 0.100000 0.700000 0.000000 0.200000 0.400000 0.500000 0.000000 0.100000 0.000000 0.500000 0.100000 0.400000 0.400000 0.500000 0.000000 0.100000 0.700000 0.100000 0.200000 0.000000 0.000000 0.100000 0.000000 0.900000 0.100000 0.700000 0.000000 0.200000 0.000000 0.200000 0.000000 0.800000 0.200000 0.000000 0.800000 0.000000 0.000000 0.000000 0.100000 0.900000 0.400000 0.000000 0.600000 0.000000 0.800000 0.200000 0.000000 0.000000 0.700000 0.000000 0.000000 0.300000 0.900000 0.000000 0.000000 0.100000 0.000000 0.000000 0.200000 0.800000 0.000000 0.000000 0.800000 0.200000 0.100000 0.000000 0.900000 0.000000 0.000000 0.100000 0.900000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KAGCCTCVVTTKCMYMATCTGTRAAATGGG MEME-7 regular expression -------------------------------------------------------------------------------- [GT]A[GA][CA]CTC[GAC][ACG][TCG]T[TG][CT][CA][CT][CA][AG]T[CT][TC][GA]T[GA][AC][AT]A[TG][GT]GG -------------------------------------------------------------------------------- Time 2131.48 secs. ******************************************************************************** ******************************************************************************** MOTIF AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 width = 31 sites = 11 llr = 246 E-value = 1.0e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 Description -------------------------------------------------------------------------------- Simplified A a42:4::31915311::395:4212519781 pos.-specific C :11137736:9:1211:5::8616624::22 probability G ::4:4::22:::6:5171:4:::3123:::: matrix T :549:33311:5:73831122:7:12313:7 bits 2.5 * 2.2 * 2.0 * * * * * 1.7 * * * * *** Relative 1.5 * * * * * * *** Entropy 1.2 * * *** * * * * **** (32.3 bits) 1.0 ** * ** *** * ** * *** **** 0.7 ** * ** ***** ** ***** **** 0.5 ** **** ***** ** ******* **** 0.2 ******* ****************** **** 0.0 ------------------------------- Multilevel ATGTACCACACTGTGTGCAACCTCCACAAAT consensus AT GTTC AA T TA G A G G T sequence C T T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr2:1527199-1527699 + 49 1.21e-15 CAACCTCCTC AAATACCCCACTGTGTGCAACCTCCTCAAAT CCCCCCATCT chr2:1525727-1526227 + 68 1.65e-14 CAACCTCCCC AAATCCCCCACTGTGTGCAACCTCCCCAAAT CC chr2:1528693-1529193 + 15 1.29e-12 CAACCTCCTC ACGTCCCCCACTGTGTGCAACCCCCACAAAT CCTCCCAGTG chr2:1528489-1528989 + 52 2.48e-12 ACCTCCCCAA ATCCCCCACACTGTGTGCAGCCTCCTCAAAT CCCCCCACTG chr1:225774702-225775202 - 24 1.79e-11 GAGAAGGGGG AAGTGCTACACAATTTTAAACAACTAGATCT TGTGAGAACT chr9:136751790-136752290 + 24 2.35e-11 atgaaagggc aagtgctacacacttttaaacaaccagatct cctgagaact chr19:36851059-36851559 + 8 5.57e-11 TACTACC ATTTGCCGAACTGTGTGTAGTATGCCTTAAT TTTGAGGTTT chr17:48492599-48493099 - 11 2.26e-10 CGAAGCTGTC ATTTATCTTACAGCTCTCAGCCTAAATAAAC ACTGAATCCG chr5:111092027-111092527 + 62 6.83e-10 GGAGAACTTT ATGTGTTGCACTGAGGGCAGTCTCCGGAAAC GCGATTCG chr19:28425296-28425796 + 16 9.41e-10 GGGGTTGGAG ATTTATCTGAAAACATGGATCCTGGGTAAAT AACGGGATGA chr6:26331267-26331767 + 68 1.83e-09 CCTACGTTTT ATTTACCTGTCAATCTGATTCATGAAAATAA TT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:1527199-1527699 1.2e-15 48_[+8]_21 chr2:1525727-1526227 1.7e-14 67_[+8]_2 chr2:1528693-1529193 1.3e-12 14_[+8]_55 chr2:1528489-1528989 2.5e-12 51_[+8]_18 chr1:225774702-225775202 1.8e-11 23_[-8]_46 chr9:136751790-136752290 2.4e-11 23_[+8]_46 chr19:36851059-36851559 5.6e-11 7_[+8]_62 chr17:48492599-48493099 2.3e-10 10_[-8]_59 chr5:111092027-111092527 6.8e-10 61_[+8]_8 chr19:28425296-28425796 9.4e-10 15_[+8]_54 chr6:26331267-26331767 1.8e-09 67_[+8]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AWDTVCCNCACWGTKTGMARCMTCCABAAAT width=31 seqs=11 chr2:1527199-1527699 ( 49) AAATACCCCACTGTGTGCAACCTCCTCAAAT 1 chr2:1525727-1526227 ( 68) AAATCCCCCACTGTGTGCAACCTCCCCAAAT 1 chr2:1528693-1529193 ( 15) ACGTCCCCCACTGTGTGCAACCCCCACAAAT 1 chr2:1528489-1528989 ( 52) ATCCCCCACACTGTGTGCAGCCTCCTCAAAT 1 chr1:225774702-225775202 ( 24) AAGTGCTACACAATTTTAAACAACTAGATCT 1 chr9:136751790-136752290 ( 24) AAGTGCTACACACTTTTAAACAACCAGATCT 1 chr19:36851059-36851559 ( 8) ATTTGCCGAACTGTGTGTAGTATGCCTTAAT 1 chr17:48492599-48493099 ( 11) ATTTATCTTACAGCTCTCAGCCTAAATAAAC 1 chr5:111092027-111092527 ( 62) ATGTGTTGCACTGAGGGCAGTCTCCGGAAAC 1 chr19:28425296-28425796 ( 16) ATTTATCTGAAAACATGGATCCTGGGTAAAT 1 chr6:26331267-26331767 ( 68) ATTTACCTGTCAATCTGATTCATGAAAATAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 12.2535 E= 1.0e-009 247 -1010 -1010 -1010 101 -181 -1010 160 1 -181 19 101 -1010 -181 -1010 233 101 -23 19 -1010 -1010 119 -1010 60 -1010 119 -1010 60 60 -23 -81 60 -99 99 -81 -99 233 -1010 -1010 -99 -99 151 -1010 -1010 133 -1010 -1010 160 60 -181 99 -1010 -99 -81 -1010 201 -99 -181 77 60 -1010 -181 -181 218 -1010 -1010 119 60 60 77 -181 -99 233 -1010 -1010 -99 133 -1010 19 1 -1010 136 -1010 1 101 99 -1010 -1010 1 -181 -1010 201 -99 99 -23 -1010 1 99 -181 -99 133 -81 -81 1 -99 19 -23 60 233 -1010 -1010 -99 201 -1010 -1010 60 218 -81 -1010 -1010 -99 -81 -1010 201 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 11 E= 1.0e-009 1.000000 0.000000 0.000000 0.000000 0.363636 0.090909 0.000000 0.545455 0.181818 0.090909 0.363636 0.363636 0.000000 0.090909 0.000000 0.909091 0.363636 0.272727 0.363636 0.000000 0.000000 0.727273 0.000000 0.272727 0.000000 0.727273 0.000000 0.272727 0.272727 0.272727 0.181818 0.272727 0.090909 0.636364 0.181818 0.090909 0.909091 0.000000 0.000000 0.090909 0.090909 0.909091 0.000000 0.000000 0.454545 0.000000 0.000000 0.545455 0.272727 0.090909 0.636364 0.000000 0.090909 0.181818 0.000000 0.727273 0.090909 0.090909 0.545455 0.272727 0.000000 0.090909 0.090909 0.818182 0.000000 0.000000 0.727273 0.272727 0.272727 0.545455 0.090909 0.090909 0.909091 0.000000 0.000000 0.090909 0.454545 0.000000 0.363636 0.181818 0.000000 0.818182 0.000000 0.181818 0.363636 0.636364 0.000000 0.000000 0.181818 0.090909 0.000000 0.727273 0.090909 0.636364 0.272727 0.000000 0.181818 0.636364 0.090909 0.090909 0.454545 0.181818 0.181818 0.181818 0.090909 0.363636 0.272727 0.272727 0.909091 0.000000 0.000000 0.090909 0.727273 0.000000 0.000000 0.272727 0.818182 0.181818 0.000000 0.000000 0.090909 0.181818 0.000000 0.727273 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWDTVCCNCACWGTKTGMARCMTCCABAAAT MEME-8 regular expression -------------------------------------------------------------------------------- A[TA][GT]T[AGC][CT][CT][ACT]CAC[TA][GA]T[GT]T[GT][CA]A[AG]C[CA]T[CG]CA[CGT]A[AT]AT -------------------------------------------------------------------------------- Time 2415.42 secs. ******************************************************************************** ******************************************************************************** MOTIF TGTGTGTGTGT MEME-9 width = 11 sites = 29 llr = 323 E-value = 6.6e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 Description -------------------------------------------------------------------------------- Simplified A :::21::::12 pos.-specific C ::1:12:::2: probability G :a1817:9:7: matrix T a:8:71a1a:8 bits 2.5 * * 2.2 * * * 2.0 * * * 1.7 ** * * * Relative 1.5 *** * * * Entropy 1.2 *** *** * (16.1 bits) 1.0 ***** *** * 0.7 ***** *** * 0.5 *********** 0.2 *********** 0.0 ----------- Multilevel TGTGTGTGTGT consensus A C CA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ----------- chr19:35947355-35947855 + 74 1.14e-07 tgtgtgtgtg tgtgtgtgtgt cgaagtctct chr20:52972205-52972705 + 1 1.14e-07 . tgtgtgtgtgt gcgagggtgt chr10:101830480-10183098 - 90 1.14e-07 . TGTGTGTGTGT ATGGGGAGGC chr7:155328565-155329065 - 51 5.21e-07 GAGATGAGGA TGTGTGTGTCT TTGGGGAGAG chr10:96580074-96580574 + 1 5.21e-07 . tgtgtgtgtga gacggagtct chr7:44490339-44490839 - 86 5.21e-07 GCGC TGTGTGTGTGA AGCGTACCTA chr1:235078182-235078682 + 81 6.49e-07 ttgtgtgtgt tgtgtttgtgt gttatgtgt chr19:33249578-33250078 - 4 8.42e-07 GTGTGAGGTG TGTATCTGTGT GTC chr19:40090478-40090978 - 2 1.03e-06 CGGAGGGGAC TGTGAGTGTGT G chr1:40257889-40258389 + 13 1.43e-06 AGGGGAAGAG TGTGTCTGTGA CACTGCCAGC chr19:38224231-38224731 - 46 1.76e-06 TCCGCGTGAA TGTGTGTGTAA ACTGCCATGC chr12:57111899-57112399 - 11 1.76e-06 AAGTTGTGCA TGTGTGTGTTT GTTTCTTGGC chr6:96924641-96925141 - 2 2.06e-06 CGTCCTAGCG TGTTTGTGTGT G chr5:1950774-1951274 + 14 2.82e-06 GTGTGTCATC TGTGCGTGTGT CATCTGCTGT chr17:74203504-74204004 + 6 3.55e-06 CTTGC TGTGAGTGTCT CTAGGGTGAT chr1:228782502-228783002 + 18 4.00e-06 tgtggtgtgg tgtaggtgtgt gtgatgcctg chr8:33513454-33513954 + 83 4.19e-06 AACTGTGTAA TGTGtttttgt gtttgtt chr17:748648-749148 - 63 5.70e-06 CCCATTATCC TGTGGCTGTGT GATTGCTCTG chr8:28401253-28401753 + 41 5.70e-06 gtgacgcgtg tgtacgtgtgt atgcgcacgt chr17:749277-749777 - 34 5.70e-06 CCCATTATCC TGTGGCTGTGT GATTGCTCTG chr19:36772245-36772745 - 21 6.91e-06 TGTCCCGGGG TGGGTGTGTGA CTTTGCGTGT chr19:682063-682563 + 52 7.52e-06 GGGTCTAGCC TGGGTGTGTAT GGAGGGTCTA chr21:45591078-45591578 - 90 7.52e-06 . TGTGTCTATGT GGAGTGTTGT chr17:77233778-77234278 - 9 9.75e-06 ACCTCATCCC TGTATTTGTCA GAATGAAC chr19:37371079-37371579 + 53 1.09e-05 GGGGAGGCCG TGTGTGTTTCA CTGTATTACC chr15:74461275-74461775 - 63 1.16e-05 GGCAACCGCT TGGATGTGTCT AAAGGGGCCG chr17:78558309-78558809 + 39 1.79e-05 ACATCATCAT TGCATGTGTAT GACATCATTG chr6:16759816-16760316 - 2 2.07e-05 GCGGCGTGAG TGTGAGTGAGT G chr6:100881084-100881584 - 2 2.21e-05 TGTGCGTCTT TGCGTCTGTCT G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:35947355-35947855 1.1e-07 73_[+9]_16 chr20:52972205-52972705 1.1e-07 [+9]_89 chr10:101830480-10183098 1.1e-07 89_[-9] chr7:155328565-155329065 5.2e-07 50_[-9]_39 chr10:96580074-96580574 5.2e-07 [+9]_89 chr7:44490339-44490839 5.2e-07 85_[-9]_4 chr1:235078182-235078682 6.5e-07 80_[+9]_9 chr19:33249578-33250078 8.4e-07 3_[-9]_86 chr19:40090478-40090978 1e-06 1_[-9]_88 chr1:40257889-40258389 1.4e-06 12_[+9]_77 chr19:38224231-38224731 1.8e-06 45_[-9]_44 chr12:57111899-57112399 1.8e-06 10_[-9]_79 chr6:96924641-96925141 2.1e-06 1_[-9]_88 chr5:1950774-1951274 2.8e-06 13_[+9]_76 chr17:74203504-74204004 3.5e-06 5_[+9]_84 chr1:228782502-228783002 4e-06 17_[+9]_72 chr8:33513454-33513954 4.2e-06 82_[+9]_7 chr17:748648-749148 5.7e-06 62_[-9]_27 chr8:28401253-28401753 5.7e-06 40_[+9]_49 chr17:749277-749777 5.7e-06 33_[-9]_56 chr19:36772245-36772745 6.9e-06 20_[-9]_69 chr19:682063-682563 7.5e-06 51_[+9]_38 chr21:45591078-45591578 7.5e-06 89_[-9] chr17:77233778-77234278 9.8e-06 8_[-9]_81 chr19:37371079-37371579 1.1e-05 52_[+9]_37 chr15:74461275-74461775 1.2e-05 62_[-9]_27 chr17:78558309-78558809 1.8e-05 38_[+9]_51 chr6:16759816-16760316 2.1e-05 1_[-9]_88 chr6:100881084-100881584 2.2e-05 1_[-9]_88 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTGTGTGTGT width=11 seqs=29 chr19:35947355-35947855 ( 74) TGTGTGTGTGT 1 chr20:52972205-52972705 ( 1) TGTGTGTGTGT 1 chr10:101830480-10183098 ( 90) TGTGTGTGTGT 1 chr7:155328565-155329065 ( 51) TGTGTGTGTCT 1 chr10:96580074-96580574 ( 1) TGTGTGTGTGA 1 chr7:44490339-44490839 ( 86) TGTGTGTGTGA 1 chr1:235078182-235078682 ( 81) TGTGTTTGTGT 1 chr19:33249578-33250078 ( 4) TGTATCTGTGT 1 chr19:40090478-40090978 ( 2) TGTGAGTGTGT 1 chr1:40257889-40258389 ( 13) TGTGTCTGTGA 1 chr19:38224231-38224731 ( 46) TGTGTGTGTAA 1 chr12:57111899-57112399 ( 11) TGTGTGTGTTT 1 chr6:96924641-96925141 ( 2) TGTTTGTGTGT 1 chr5:1950774-1951274 ( 14) TGTGCGTGTGT 1 chr17:74203504-74204004 ( 6) TGTGAGTGTCT 1 chr1:228782502-228783002 ( 18) TGTAGGTGTGT 1 chr8:33513454-33513954 ( 83) TGTGTTTTTGT 1 chr17:748648-749148 ( 63) TGTGGCTGTGT 1 chr8:28401253-28401753 ( 41) TGTACGTGTGT 1 chr17:749277-749777 ( 34) TGTGGCTGTGT 1 chr19:36772245-36772745 ( 21) TGGGTGTGTGA 1 chr19:682063-682563 ( 52) TGGGTGTGTAT 1 chr21:45591078-45591578 ( 90) TGTGTCTATGT 1 chr17:77233778-77234278 ( 9) TGTATTTGTCA 1 chr19:37371079-37371579 ( 53) TGTGTGTTTCA 1 chr15:74461275-74461775 ( 63) TGGATGTGTCT 1 chr17:78558309-78558809 ( 39) TGCATGTGTAT 1 chr6:16759816-16760316 ( 2) TGTGAGTGAGT 1 chr6:100881084-100881584 ( 2) TGCGTCTGTCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 11 n= 54000 bayes= 12.1115 E= 6.6e-003 -1150 -1150 -1150 247 -1150 -1150 165 -1150 -1150 -221 -163 220 20 -1150 125 -239 -80 -221 -163 200 -1150 -63 111 -80 -1150 -1150 -1150 247 -239 -1150 149 -139 -239 -1150 -1150 242 -80 -63 104 -239 42 -1150 -1150 207 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 11 nsites= 29 E= 6.6e-003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.068966 0.103448 0.827586 0.206897 0.000000 0.758621 0.034483 0.103448 0.068966 0.103448 0.724138 0.000000 0.206897 0.689655 0.103448 0.000000 0.000000 0.000000 1.000000 0.034483 0.000000 0.896552 0.068966 0.034483 0.000000 0.000000 0.965517 0.103448 0.206897 0.655172 0.034483 0.241379 0.000000 0.000000 0.758621 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTGTGT MEME-9 regular expression -------------------------------------------------------------------------------- TGT[GA]T[GC]TGT[GC][TA] -------------------------------------------------------------------------------- Time 2698.87 secs. ******************************************************************************** ******************************************************************************** MOTIF WCCCTCCCCAAA MEME-10 width = 12 sites = 18 llr = 231 E-value = 4.0e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 Description -------------------------------------------------------------------------------- Simplified A 521:1::2:a88 pos.-specific C :89a:9a7a:2: probability G :::::::::::2 matrix T 5:::91:1:::: bits 2.5 * 2.2 * * 2.0 * * 1.7 ** * *** Relative 1.5 * ** * **** Entropy 1.2 * ***** **** (18.5 bits) 1.0 ******* **** 0.7 ************ 0.5 ************ 0.2 ************ 0.0 ------------ Multilevel ACCCTCCCCAAA consensus TA A G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr7:155328565-155329065 + 72 1.30e-07 TCCTCATCTC TCCCTCCCCAAA GACACCCACA chr16:30429612-30430112 + 3 1.30e-07 GA ACCCTCCCCAAA ACGCGGGAGA chr3:15860017-15860517 - 68 1.30e-07 TTGGCTCCCC ACCCTCCCCAAA CCCAGGGGCA chr22:42188800-42189300 - 32 2.03e-07 TGCCTGCTTG TCCCTCCACAAA GCAGTTTGTT chr2:1528489-1528989 + 12 2.76e-07 TACCTTGTGC AACCTCCCCAAA TCCCACCCAC chr6:30647081-30647581 + 67 3.90e-07 gcggggagag ACCCTCCTCAAA GCCGGTGCGT chr19:35545251-35545751 + 48 5.36e-07 TGGCCGGAAG TCACTCCCCAAA GCGCTGGGCC chr3:4978473-4978973 + 42 8.08e-07 CGCCCCTCGG TCCCTCCCCAAG GCGGGCAATT chr21:33025409-33025909 + 70 8.08e-07 CCTCCTCCAG TCCCTCCCCAAG AATCTCCCGG chr1:236084315-236084815 - 68 8.08e-07 TCACTGCAGC ACCCTCCCCAAG TGTGCCTCAT chr2:1527199-1527699 + 10 8.08e-07 ACTGTGTGC AACCTCCTCAAA TCCTCCGCCA chr5:69234802-69235302 - 25 8.08e-07 GCCTCACCTG TCCCTCCCCAAG GAAGTCCAGC chr1:26695404-26695904 - 20 8.90e-07 CTCGCTCCCT TCCCTTCACAAA GGAGGAGGGG chr2:1525727-1526227 + 31 1.20e-06 GACTGTTTAC AACCTTCCCAAA TCTCCCCACT chr8:37698384-37698884 + 4 1.20e-06 CCG TCCCTCCCCACA GCCGGACCCT chr22:36481151-36481651 - 54 1.64e-06 TTTTCCCAGT TCCCTCCACACA TGTCCCTTCT chr1:12539682-12540182 - 65 2.88e-06 CAACGTCACA AACCACCCCAAA ACTTTATGGC chr21:6565296-6565796 + 7 4.31e-06 ctccac acactccacaca caccacacac -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:155328565-155329065 1.3e-07 71_[+10]_17 chr16:30429612-30430112 1.3e-07 2_[+10]_86 chr3:15860017-15860517 1.3e-07 67_[-10]_21 chr22:42188800-42189300 2e-07 31_[-10]_57 chr2:1528489-1528989 2.8e-07 11_[+10]_77 chr6:30647081-30647581 3.9e-07 66_[+10]_22 chr19:35545251-35545751 5.4e-07 47_[+10]_41 chr3:4978473-4978973 8.1e-07 41_[+10]_47 chr21:33025409-33025909 8.1e-07 69_[+10]_19 chr1:236084315-236084815 8.1e-07 67_[-10]_21 chr2:1527199-1527699 8.1e-07 9_[+10]_79 chr5:69234802-69235302 8.1e-07 24_[-10]_64 chr1:26695404-26695904 8.9e-07 19_[-10]_69 chr2:1525727-1526227 1.2e-06 30_[+10]_58 chr8:37698384-37698884 1.2e-06 3_[+10]_85 chr22:36481151-36481651 1.6e-06 53_[-10]_35 chr1:12539682-12540182 2.9e-06 64_[-10]_24 chr21:6565296-6565796 4.3e-06 6_[+10]_82 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WCCCTCCCCAAA width=12 seqs=18 chr7:155328565-155329065 ( 72) TCCCTCCCCAAA 1 chr16:30429612-30430112 ( 3) ACCCTCCCCAAA 1 chr3:15860017-15860517 ( 68) ACCCTCCCCAAA 1 chr22:42188800-42189300 ( 32) TCCCTCCACAAA 1 chr2:1528489-1528989 ( 12) AACCTCCCCAAA 1 chr6:30647081-30647581 ( 67) ACCCTCCTCAAA 1 chr19:35545251-35545751 ( 48) TCACTCCCCAAA 1 chr3:4978473-4978973 ( 42) TCCCTCCCCAAG 1 chr21:33025409-33025909 ( 70) TCCCTCCCCAAG 1 chr1:236084315-236084815 ( 68) ACCCTCCCCAAG 1 chr2:1527199-1527699 ( 10) AACCTCCTCAAA 1 chr5:69234802-69235302 ( 25) TCCCTCCCCAAG 1 chr1:26695404-26695904 ( 20) TCCCTTCACAAA 1 chr2:1525727-1526227 ( 31) AACCTTCCCAAA 1 chr8:37698384-37698884 ( 4) TCCCTCCCCACA 1 chr22:36481151-36481651 ( 54) TCCCTCCACACA 1 chr1:12539682-12540182 ( 65) AACCACCCCAAA 1 chr21:6565296-6565796 ( 7) ACACTCCACACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 11.6685 E= 4.0e-003 147 -1081 -1081 147 30 128 -1081 -1081 -70 148 -1081 -1081 -1081 165 -1081 -1081 -170 -1081 -1081 239 -1081 148 -1081 -70 -1081 165 -1081 -1081 30 106 -1081 -70 -1081 165 -1081 -1081 247 -1081 -1081 -1081 221 -94 -1081 -1081 211 -1081 -52 -1081 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 18 E= 4.0e-003 0.500000 0.000000 0.000000 0.500000 0.222222 0.777778 0.000000 0.000000 0.111111 0.888889 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.055556 0.000000 0.000000 0.944444 0.000000 0.888889 0.000000 0.111111 0.000000 1.000000 0.000000 0.000000 0.222222 0.666667 0.000000 0.111111 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 0.777778 0.000000 0.222222 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WCCCTCCCCAAA MEME-10 regular expression -------------------------------------------------------------------------------- [AT][CA]CCTCC[CA]CAA[AG] -------------------------------------------------------------------------------- Time 2978.65 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:55051525-55052025 8.39e-01 100 chr21:41766760-41767260 7.88e-01 62_[+2(4.48e-05)]_22 chr5:139517786-139518286 9.98e-01 100 chr9:132354595-132355095 1.00e+00 100 chr17:26603652-26604152 1.13e-05 27_[-1(5.83e-07)]_42 chrX:41084836-41085336 2.04e-01 75_[+2(9.69e-05)]_9 chr5:140400612-140401112 8.48e-01 100 chr5:115928858-115929358 1.76e-06 22_[-4(5.81e-12)]_6_[-4(3.16e-11)]_\ 28 chr21:42010008-42010508 5.55e-01 100 chr1:174999227-174999727 7.19e-01 100 chr7:100705380-100705880 5.14e-01 100 chr6:149963657-149964157 1.37e-01 100 chr1:91885863-91886363 2.62e-01 100 chr8:99012910-99013410 1.74e-03 58_[+4(5.74e-08)]_20 chr20:37095802-37096302 1.50e-03 53_[+2(5.47e-05)]_31 chr15:69452751-69453251 4.16e-01 100 chr15:74223036-74223536 2.66e-09 11_[-7(1.14e-13)]_59 chr20:50165934-50166434 7.93e-05 69_[+1(1.20e-07)] chr1:54715671-54716171 5.62e-01 100 chr5:181169667-181170167 9.89e-01 100 chr21:45591078-45591578 5.60e-15 9_[-1(2.30e-11)]_17_[+4(1.72e-09)]_\ 10_[-9(7.52e-06)] chr15:75368403-75368903 3.80e-01 25_[+8(8.71e-05)]_44 chr15:65286219-65286719 9.61e-01 100 chr1:89995037-89995537 5.76e-01 100 chr5:6633436-6633936 9.92e-01 100 chr1:46340683-46341183 7.18e-03 49_[-2(1.33e-05)]_35 chr5:124987722-124988222 1.37e-17 44_[-5(4.90e-25)]_7 chr6:170502397-170502897 9.48e-03 11_[+5(1.81e-05)]_23_[-2(8.83e-05)]_\ 1 chr19:35612604-35613104 5.92e-01 100 chr19:13747305-13747805 6.65e-03 73_[+2(3.11e-06)]_11 chr21:46228254-46228754 7.90e-01 100 chr12:109998985-10999948 4.73e-04 11_[-2(6.23e-06)]_36_[-6(2.42e-06)]_\ 8 chr19:2945126-2945626 2.89e-01 12_[-2(4.76e-06)]_72 chr17:15999373-15999873 9.87e-01 100 chr16:4183422-4183922 1.78e-01 100 chr17:40140282-40140782 9.96e-01 100 chr8:37698384-37698884 7.70e-03 3_[+10(1.20e-06)]_85 chr1:156661290-156661790 4.98e-12 65_[+1(1.02e-15)]_4 chr1:183471149-183471649 6.82e-01 100 chr20:44475715-44476215 1.00e+00 100 chr19:36851059-36851559 4.54e-14 7_[+8(5.57e-11)]_26_[+1(5.56e-08)]_\ 5 chr19:39507258-39507758 9.91e-01 100 chr15:70097403-70097903 9.94e-01 100 chr7:98878706-98879206 3.12e-01 100 chr19:58327057-58327557 1.30e-01 24_[-9(3.32e-05)]_65 chr1:10854793-10855293 1.33e-02 35_[+2(9.69e-05)]_49 chr5:41904198-41904698 4.56e-03 73_[-2(3.59e-06)]_11 chr6:100881084-100881584 1.48e-01 1_[-9(2.21e-05)]_88 chr17:45161187-45161687 4.83e-01 84_[+2(3.11e-06)] chr13:95535145-95535645 3.77e-02 100 chr11:77474157-77474657 9.77e-01 100 chr16:21301535-21302035 2.07e-01 58_[+1(9.90e-05)]_11 chr7:112450916-112451416 2.30e-01 100 chr22:24555563-24556063 9.17e-01 100 chr6:89081633-89082133 8.77e-01 100 chr12:389118-389618 7.17e-03 72_[+2(1.24e-06)]_12 chr17:68511868-68512368 2.04e-02 25_[-2(2.64e-05)]_59 chr16:2682217-2682717 8.17e-01 100 chr19:44500175-44500675 3.30e-01 100 chr19:12792232-12792732 9.82e-01 100 chr3:15860017-15860517 2.69e-04 67_[-10(1.30e-07)]_21 chr20:36236167-36236667 3.86e-01 100 chr1:111990050-111990550 4.75e-02 10_[-2(1.50e-05)]_74 chr1:24642579-24643079 2.82e-06 27_[-1(6.62e-08)]_42 chr19:33249578-33250078 1.01e-13 3_[-9(8.42e-07)]_12_[-1(2.50e-10)]_\ 2_[+4(8.70e-09)]_4_[+10(1.30e-05)]_3 chr17:68019672-68020172 4.98e-02 30_[+6(1.24e-05)]_41 chr12:123458009-12345850 2.67e-02 47_[-2(4.15e-06)]_37 chr5:178626489-178626989 6.57e-01 100 chr6:28080693-28081193 4.27e-01 100 chr17:7242787-7243287 2.37e-01 100 chr15:73699645-73700145 7.65e-12 36_[+7(1.46e-14)]_34 chr17:59291798-59292298 1.77e-18 8_[+6(7.08e-12)]_5_[+2(7.11e-06)]_1_\ [+3(1.66e-14)]_10 chr5:34007670-34008170 8.54e-01 100 chr5:79612420-79612920 3.26e-01 100 chr7:112790034-112790534 3.46e-02 100 chr1:21345587-21346087 8.67e-01 100 chr11:78079601-78080101 5.06e-02 32_[+2(1.31e-07)]_52 chr12:38316451-38316951 8.32e-02 45_[-1(9.46e-05)]_24 chr17:50560473-50560973 1.51e-01 53_[+2(3.64e-05)]_31 chr6:144284838-144285338 8.42e-01 100 chr7:139133414-139133914 3.12e-01 100 chr19:38618568-38619068 6.58e-01 100 chr14:23006802-23007302 9.11e-01 100 chr17:19648753-19649253 7.88e-01 100 chr5:14664200-14664700 1.92e-03 19_[+2(1.05e-06)]_65 chr1:211258800-211259300 6.13e-02 30_[-5(9.91e-05)]_21 chr9:132669711-132670211 3.61e-01 100 chr13:49936023-49936523 4.20e-01 77_[+2(6.65e-05)]_7 chr19:17605971-17606471 9.68e-01 100 chr17:63600613-63601113 3.51e-01 100 chr12:105107674-10510817 9.78e-01 100 chr17:82037239-82037739 3.99e-01 100 chr17:74203504-74204004 8.24e-04 5_[+9(3.55e-06)]_84 chr7:108569869-108570369 7.58e-02 54_[-10(9.34e-05)]_34 chr16:30526882-30527382 5.38e-02 54_[+2(2.12e-05)]_30 chr9:128947576-128948076 1.87e-01 32_[-2(8.05e-05)]_52 chr1:224113959-224114459 7.70e-02 32_[+2(3.11e-06)]_52 chr5:115545025-115545525 9.14e-04 19_[+5(8.66e-08)]_32 chr6:63635768-63636268 8.69e-01 100 chr6:24359677-24360177 3.01e-01 100 chr8:22604387-22604887 5.91e-01 100 chr19:37218037-37218537 7.14e-02 46_[+9(8.22e-05)]_43 chr4:2009184-2009684 7.10e-01 32_[+2(8.83e-05)]_52 chr1:236795226-236795726 5.87e-01 35_[+5(6.69e-05)]_16 chr6:31971706-31972206 2.38e-01 100 chr10:75111529-75112029 1.26e-02 5_[-2(9.69e-05)]_79 chr6:16759816-16760316 4.33e-02 1_[-9(2.07e-05)]_49_[+2(3.64e-05)]_\ 23 chr12:53501173-53501673 1.88e-03 19_[-2(3.59e-06)]_65 chr21:46458880-46459380 9.72e-01 100 chr10:95561543-95562043 1.49e-08 39_[+7(1.42e-12)]_31 chr12:63779706-63780206 5.01e-01 100 chr1:235504718-235505218 2.02e-01 100 chr19:39033050-39033550 2.21e-16 2_[-6(5.40e-15)]_14_[-1(6.69e-12)]_\ 24 chr20:3820066-3820566 9.61e-01 100 chr6:158566403-158566903 2.90e-02 100 chr10:132965164-13296566 2.82e-01 100 chr1:229221327-229221827 9.97e-03 100 chr17:59619626-59620126 6.77e-01 100 chr21:31873835-31874335 6.02e-01 100 chr19:8005695-8006195 5.44e-01 42_[-5(8.62e-05)]_9 chr12:123232743-12323324 5.12e-03 18_[-1(6.28e-07)]_27_[+2(2.12e-05)]_\ 8 chr15:70196566-70197066 1.26e-01 100 chr2:3574930-3575430 6.26e-02 100 chr5:119071046-119071546 2.93e-01 100 chr2:113583665-113584165 2.11e-01 100 chr21:31732212-31732712 1.00e+00 100 chr6:27479358-27479858 4.76e-05 8_[+1(1.49e-06)]_61 chr21:43857406-43857906 2.43e-22 17_[-3(6.69e-18)]_1_[-2(4.95e-05)]_\ 5_[-6(5.03e-14)]_1 chr7:139339841-139340341 1.75e-13 5_[+1(7.17e-09)]_14_[+6(1.01e-12)]_\ 5_[+2(1.68e-05)] chr22:20981734-20982234 9.93e-01 100 chr15:65517256-65517756 1.91e-01 [-2(3.11e-06)]_84 chr11:67054716-67055216 2.77e-01 100 chr15:69160548-69161048 7.90e-01 100 chr6:28399625-28400125 3.61e-02 100 chr7:44490339-44490839 2.13e-05 85_[-9(5.21e-07)]_4 chr5:69093912-69094412 7.24e-01 100 chr21:38805374-38805874 1.09e-01 24_[-2(6.23e-06)]_34_[+2(8.83e-05)]_\ 10 chr16:3401153-3401653 9.83e-01 100 chr8:630770-631270 1.31e-02 100 chr5:59649174-59649674 8.56e-03 100 chr13:30617544-30618044 9.71e-01 100 chr3:112561472-112561972 4.49e-01 12_[-2(8.05e-05)]_72 chr12:112387664-11238816 5.79e-23 38_[-1(1.13e-12)]_[-3(2.18e-18)] chr12:107093864-10709436 9.30e-03 43_[-2(9.19e-06)]_41 chr19:2378614-2379114 8.58e-22 11_[+5(1.92e-27)]_40 chr12:50400919-50401419 9.54e-01 100 chr12:89709711-89710211 7.21e-01 100 chr19:39244408-39244908 2.55e-02 61_[-7(2.76e-05)]_9 chr19:40420974-40421474 8.56e-02 100 chr19:33795549-33796049 9.82e-01 100 chr19:15125291-15125791 9.56e-02 23_[+10(6.94e-05)]_65 chr17:48048266-48048766 8.32e-01 100 chr22:21982574-21983074 8.64e-01 100 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chr20:45971367-45971867 3.32e-01 100 chr17:1293386-1293886 4.82e-04 4_[+1(7.22e-08)]_13_[+1(5.91e-05)]_\ 21 chr19:36604662-36605162 2.34e-04 68_[-1(2.50e-07)]_1 chr1:1000577-1001077 9.94e-01 100 chr19:40090478-40090978 4.49e-06 1_[-9(1.03e-06)]_3_[-1(2.92e-05)]_\ 54 chr10:22229160-22229660 5.60e-03 52_[-3(4.37e-05)]_17 chr15:72117526-72118026 1.78e-01 100 chr1:42335137-42335637 9.82e-01 100 chr21:29217715-29218215 1.24e-02 1_[-8(7.92e-05)]_68 chr15:74546037-74546537 9.35e-01 100 chr15:74614673-74615173 1.00e+00 100 chr1:36088609-36089109 6.47e-01 100 chr17:35587069-35587569 2.31e-01 100 chr21:34073414-34073914 4.24e-01 100 chr10:99620832-99621332 9.91e-01 100 chr9:136751790-136752290 2.19e-10 23_[+8(2.35e-11)]_46 chr4:189233710-189234210 3.36e-04 [+1(2.98e-08)]_3_[+1(2.98e-08)]_3_\ [+1(2.31e-07)]_1 chr12:109573064-10957356 3.06e-01 81_[+2(7.33e-05)]_3 chr1:244970753-244971253 4.54e-01 47_[-4(3.37e-05)]_31 chr17:18087643-18088143 6.80e-02 77_[+2(3.28e-05)]_7 chr12:130764516-13076501 4.09e-06 12_[+1(6.77e-07)]_34_[-4(1.90e-07)]_\ 1 chr19:36687092-36687592 3.91e-06 19_[-1(1.31e-07)]_50 chr17:45148406-45148906 9.56e-02 100 chr5:141969023-141969523 1.13e-01 100 chr16:21599266-21599766 3.37e-01 100 chr6:87322344-87322844 5.83e-01 4_[+2(3.28e-05)]_80 chr6:116859218-116859718 2.19e-01 100 chr6:24774896-24775396 4.33e-01 24_[-2(3.28e-05)]_60 chr3:53347406-53347906 9.88e-01 100 chr19:39237111-39237611 2.62e-02 100 chrX:104156557-104157057 2.24e-03 4_[+2(5.47e-05)]_30_[-5(9.44e-05)]_\ 1 chr17:34580110-34580610 2.26e-01 100 chr19:40920894-40921394 7.19e-03 100 chr1:212791622-212792122 2.69e-01 100 chr21:43850847-43851347 1.67e-01 100 chr4:189234913-189235413 4.58e-05 21_[+1(2.98e-08)]_3_[+1(1.10e-07)]_\ 14 chr19:34734073-34734573 9.95e-01 100 chr11:64245759-64246259 2.54e-01 100 chr12:12266861-12267361 5.88e-01 100 chr16:30065071-30065571 9.81e-01 100 chr9:95875704-95876204 5.66e-01 75_[+2(1.18e-05)]_9 chr1:145280975-145281475 2.30e-07 50_[+7(1.00e-11)]_20 chr19:39390701-39391201 5.50e-01 9_[-2(3.28e-05)]_75 chr19:35995149-35995649 9.42e-01 100 chr22:37844516-37845016 3.23e-14 17_[+1(6.69e-12)]_14_[+6(5.92e-12)]_\ 9 chr17:44014719-44015219 2.70e-01 100 chr1:53220252-53220752 1.40e-01 100 chr12:48681708-48682208 7.75e-01 100 chr16:1092944-1093444 2.88e-01 25_[+10(4.95e-05)]_63 chr16:28863109-28863609 1.05e-05 26_[-6(1.17e-09)]_45 chr19:38336503-38337003 3.95e-02 84_[-2(4.04e-05)] chr19:682063-682563 4.69e-06 2_[-4(1.07e-07)]_2_[-4(1.07e-07)]_2_\ [-4(1.79e-07)]_2_[-4(1.07e-07)]_4 chr20:23361518-23362018 9.82e-01 100 chr16:683643-684143 9.40e-01 100 chr11:78188207-78188707 9.62e-08 38_[-7(2.55e-12)]_32 chr1:224615761-224616261 1.17e-03 40_[+2(2.12e-05)]_44 chr3:51538412-51538912 9.99e-01 100 chr21:25607256-25607756 4.13e-03 46_[+2(1.04e-05)]_38 chr9:133030714-133031214 7.25e-02 29_[-6(8.91e-06)]_42 chr1:206612159-206612659 7.34e-01 2_[-2(5.47e-05)]_82 chr15:72783551-72784051 9.83e-01 100 chr21:33025409-33025909 1.02e-03 28_[+2(1.70e-06)]_13_\ [+10(8.20e-05)]_[+10(8.08e-07)]_19 chr17:77233778-77234278 3.29e-04 8_[-9(9.75e-06)]_6_[-8(5.61e-06)]_\ 44 chr9:105244104-105244604 7.27e-01 100 chr5:59303215-59303715 1.48e-05 3_[+1(5.31e-09)]_31_[+6(3.60e-05)]_\ 6 chr21:28992643-28993143 2.25e-01 100 chr19:40717649-40718149 7.64e-02 100 chr21:44939695-44940195 6.52e-01 100 chr17:51153348-51153848 8.36e-01 100 chr13:113208606-11320910 6.32e-01 100 chr1:200669501-200670001 7.74e-01 100 chr16:29973305-29973805 1.73e-01 100 chr17:67993797-67994297 3.61e-02 22_[-2(3.64e-05)]_36_[-2(2.99e-07)]_\ 10 chr15:84981244-84981744 9.61e-01 100 chr12:123601828-12360232 9.09e-01 100 chr10:42782452-42782952 8.98e-02 75_[+2(9.19e-06)]_9 chr21:46286023-46286523 9.96e-01 100 chr6:143511305-143511805 7.96e-01 100 chr12:124914536-12491503 2.80e-02 100 chr16:30698064-30698564 8.94e-02 100 chr19:4576108-4576608 7.83e-03 1_[+2(6.65e-05)]_83 chr17:59209674-59210174 2.65e-04 48_[-2(4.29e-07)]_36 chr14:35826360-35826860 8.79e-01 100 chr17:82065643-82066143 8.77e-01 100 chr13:52194223-52194723 1.96e-03 23_[+2(1.33e-05)]_61 chr5:111092027-111092527 1.19e-04 61_[+8(6.83e-10)]_8 chr12:51025917-51026417 2.81e-01 100 chr19:35947355-35947855 1.25e-12 42_[+1(1.02e-15)]_[+9(1.14e-07)]_16 chr8:94719608-94720108 6.12e-01 100 chr16:30874993-30875493 5.59e-01 100 chr17:75012362-75012862 8.15e-01 100 chr1:99969664-99970164 9.41e-01 100 chr17:18780966-18781466 7.44e-01 100 chr21:32612315-32612815 1.51e-01 100 chr1:234723978-234724478 1.92e-03 61_[-2(7.11e-06)]_23 chr19:41310158-41310658 9.75e-02 100 chr9:137240417-137240917 9.85e-01 100 chr19:36054120-36054620 5.53e-01 100 chr21:45075070-45075570 9.31e-01 100 chr12:106357535-10635803 2.23e-01 100 chr17:748648-749148 5.06e-04 62_[-9(5.70e-06)]_27 chr17:32341949-32342449 6.53e-01 100 chr15:64387543-64388043 4.79e-01 100 chr1:26695404-26695904 1.33e-04 3_[+2(4.76e-06)]_[-10(8.90e-07)]_69 chr6:131628016-131628516 7.18e-02 19_[-2(4.76e-06)]_65 chr20:33401276-33401776 1.72e-01 100 chr1:93078947-93079447 9.53e-01 100 chr21:39183023-39183523 4.34e-03 81_[+2(8.39e-08)]_3 chr7:102572329-102572829 6.14e-01 100 chr6:143450521-143451021 3.37e-01 100 chr10:63520786-63521286 1.63e-02 100 chr1:16644502-16645002 7.17e-01 100 chr2:11743847-11744347 4.04e-07 20_[-7(3.73e-12)]_50 chr2:223957184-223957684 2.44e-03 54_[+2(5.44e-06)]_30 chr10:133394063-13339456 9.98e-01 100 chr19:35643422-35643922 1.14e-01 2_[-3(3.15e-05)]_67 chr16:25258014-25258514 5.98e-01 100 chr6:157323318-157323818 1.15e-01 54_[+2(2.64e-05)]_30 chr15:89893835-89894335 8.21e-01 100 chr8:27948380-27948880 1.17e-03 74_[+10(3.28e-05)]_14 chr1:44213172-44213672 6.10e-01 100 chr2:241102113-241102613 4.98e-01 3_[+2(1.89e-05)]_81 chr2:232550400-232550900 5.68e-01 100 chr5:176388756-176389256 2.17e-01 68_[-2(8.05e-05)]_16 chr10:17201431-17201931 2.69e-01 50_[+2(8.07e-06)]_34 chr19:35545251-35545751 1.05e-02 47_[+10(5.36e-07)]_41 chr19:37655848-37656348 7.87e-01 100 chr20:45972075-45972575 1.63e-01 100 chr1:63523112-63523612 2.36e-03 61_[-1(8.24e-05)]_8 chr1:1374997-1375497 3.48e-01 7_[+10(3.28e-05)]_81 chr17:30906047-30906547 9.92e-01 100 chr1:227735043-227735543 4.75e-01 100 chr19:10416593-10417093 5.74e-01 100 chr1:37989835-37990335 2.86e-01 100 chr1:228082122-228082622 1.03e-01 100 chr21:43728515-43729015 9.99e-02 100 chr1:163321603-163322103 2.65e-01 100 chr17:78558309-78558809 1.16e-02 38_[+9(1.79e-05)]_51 chr6:4775738-4776238 9.94e-01 100 chr15:49046311-49046811 1.73e-02 7_[-2(4.15e-06)]_56_[-2(4.76e-06)]_\ 5 chr20:58650974-58651474 5.86e-01 24_[-2(6.65e-05)]_60 chr21:32771773-32772273 1.90e-01 [-2(4.76e-06)]_84 chr12:1198821-1199321 4.12e-02 69_[+8(7.92e-05)] chr7:103149221-103149721 9.65e-01 100 chr19:1383570-1384070 4.62e-01 100 chr19:1021409-1021909 4.49e-01 100 chr21:46635663-46636163 9.26e-01 100 chr1:236097028-236097528 3.03e-04 6_[-4(9.74e-07)]_7_[-4(4.05e-10)]_7_\ [-4(4.05e-10)]_14 chr1:2871218-2871718 3.44e-01 100 chr1:40257889-40258389 9.81e-03 12_[+9(1.43e-06)]_77 chr5:40835080-40835580 1.58e-01 100 chr1:183471821-183472321 7.32e-03 9_[+5(8.74e-05)]_42 chr2:1528489-1528989 1.06e-10 11_[+10(2.76e-07)]_28_\ [+8(2.48e-12)]_18 chr10:93702422-93702922 3.23e-01 100 chrUn_KI270467v1:2903-34 3.18e-13 2_[+7(5.60e-09)]_8_[+1(2.50e-07)]_\ [-4(3.79e-07)]_7 chr10:3314598-3315098 2.36e-04 3_[-8(4.44e-05)]_66 chr3:4978473-4978973 2.12e-02 41_[+10(8.08e-07)]_47 chr15:65610889-65611389 6.67e-01 100 chr21:39313555-39314055 3.11e-01 100 chrX:73944016-73944516 4.38e-01 100 chr1:125179939-125180439 1.48e-02 53_[+1(6.28e-07)]_16 chr1:155244567-155245067 2.51e-01 22_[-2(1.68e-05)]_14_[-2(4.48e-05)]_\ 14_[-2(4.76e-06)]_2 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (10) found. ******************************************************************************** CPU: surya ********************************************************************************