******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.12.0 (Release date: Tue Jun 27 16:22:50 2017 -0700) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme-suite.org . This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme-suite.org . ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF660.IDR0.05.filt.narrowPeak.inPolsteinDNase.summitPlusMinus250bp.MemeChipResults/seqs-centered ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr1:154627781-154628281 1.0000 100 chr19:39390690-39391190 1.0000 100 chr12:44948623-44949123 1.0000 100 chr17:39154263-39154763 1.0000 100 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chr3:37197613-37198113 1.0000 100 chr15:70062307-70062807 1.0000 100 chr1:234724153-234724653 1.0000 100 chr3:55692915-55693415 1.0000 100 chr2:95333888-95334388 1.0000 100 chr1:209884518-209885018 1.0000 100 chr6:149011880-149012380 1.0000 100 chr5:132389703-132390203 1.0000 100 chr1:93078913-93079413 1.0000 100 chr1:37989855-37990355 1.0000 100 chrX:73944048-73944548 1.0000 100 chr1:151070353-151070853 1.0000 100 chr19:18349515-18350015 1.0000 100 chr1:232620479-232620979 1.0000 100 chr1:214469215-214469715 1.0000 100 chr1:1375033-1375533 1.0000 100 chr1:109438736-109439236 1.0000 100 chr1:44213157-44213657 1.0000 100 chr11:106078021-10607852 1.0000 100 chr7:23298894-23299394 1.0000 100 chr10:124917810-12491831 1.0000 100 chr5:399675-400175 1.0000 100 chr5:172437410-172437910 1.0000 100 chr17:70661149-70661649 1.0000 100 chr15:89383546-89384046 1.0000 100 chr15:65610930-65611430 1.0000 100 chr2:55014920-55015420 1.0000 100 chr4:53011921-53012421 1.0000 100 chr6:131628048-131628548 1.0000 100 chr8:30382234-30382734 1.0000 100 chr9:129334002-129334502 1.0000 100 chr19:35757455-35757955 1.0000 100 chr1:153880943-153881443 1.0000 100 chr6:53927177-53927677 1.0000 100 chr19:48539554-48540054 1.0000 100 chr12:57846932-57847432 1.0000 100 chr2:170530187-170530687 1.0000 100 chr7:116547259-116547759 1.0000 100 chr1:80054126-80054626 1.0000 100 chr15:33126616-33127116 1.0000 100 chr10:21724680-21725180 1.0000 100 chr1:23544613-23545113 1.0000 100 chr10:112565447-11256594 1.0000 100 chr10:87586164-87586664 1.0000 100 chr17:28599396-28599896 1.0000 100 chr1:76759959-76760459 1.0000 100 chr11:85628101-85628601 1.0000 100 chrX:78103807-78104307 1.0000 100 chr1:197180308-197180808 1.0000 100 chr22:25942957-25943457 1.0000 100 chr20:32270580-32271080 1.0000 100 chr4:82374296-82374796 1.0000 100 chr1:229221077-229221577 1.0000 100 chr5:124908556-124909056 1.0000 100 chr7:113421625-113422125 1.0000 100 chr5:124706624-124707124 1.0000 100 chr1:212488389-212488889 1.0000 100 chr5:66757140-66757640 1.0000 100 chr16:84138675-84139175 1.0000 100 chr5:10601227-10601727 1.0000 100 chr7:112422833-112423333 1.0000 100 chr16:69073279-69073779 1.0000 100 chr6:155177323-155177823 1.0000 100 chr6:118800479-118800979 1.0000 100 chr5:177546330-177546830 1.0000 100 chr13:112102298-11210279 1.0000 100 chr5:124661428-124661928 1.0000 100 chr6:43630028-43630528 1.0000 100 chr4:185095932-185096432 1.0000 100 chr12:40224917-40225417 1.0000 100 chr12:54039773-54040273 1.0000 100 chr5:157511503-157512003 1.0000 100 chr15:38354223-38354723 1.0000 100 chr8:120859583-120860083 1.0000 100 chr4:38620878-38621378 1.0000 100 chr12:53501377-53501877 1.0000 100 chr10:116891095-11689159 1.0000 100 chr17:78974979-78975479 1.0000 100 chr3:14125641-14126141 1.0000 100 chr22:37330363-37330863 1.0000 100 chr6:37171929-37172429 1.0000 100 chr1:200510053-200510553 1.0000 100 chr1:46522108-46522608 1.0000 100 chr1:110338807-110339307 1.0000 100 chr1:223819689-223820189 1.0000 100 chr16:1271747-1272247 1.0000 100 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF660.IDR0.05.filt.narrowPeak.inPolsteinDNase.summitPlusMinus250bp.MemeChipResults/seqs-centered -oc /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF660.IDR0.05.filt.narrowPeak.inPolsteinDNase.summitPlusMinus250bp.MemeChipResults/meme_out -mod zoops -nmotifs 10 -minw 5 -maxw 50 -bfile /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF660.IDR0.05.filt.narrowPeak.inPolsteinDNase.summitPlusMinus250bp.MemeChipResults/background -dna -revcomp -nostatus model: mod= zoops nmotifs= 10 evt= inf object function= E-value of product of p-values width: minw= 5 maxw= 50 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 600 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 60000 N= 600 shuffle= -1 strands: + - sample: seed= 0 ctfrac= -1 maxwords= -1 Letter frequencies in dataset: A 0.226 C 0.274 G 0.274 T 0.226 Background letter frequencies (from /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF660.IDR0.05.filt.narrowPeak.inPolsteinDNase.summitPlusMinus250bp.MemeChipResults/background): A 0.236 C 0.264 G 0.264 T 0.236 ******************************************************************************** ******************************************************************************** MOTIF YTGGCMMKSTGCCAAG MEME-1 width = 16 sites = 108 llr = 1364 E-value = 3.5e-184 ******************************************************************************** -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::::53113:::972 pos.-specific C 5:::a3514::aa1:1 probability G ::aa:114519:::37 matrix T 4a:::213:6:::::1 bits 2.1 1.9 **** ** 1.7 **** ** 1.5 **** *** Relative 1.2 **** **** Entropy 1.0 **** ***** (18.2 bits) 0.8 ***** ***** 0.6 ***** ****** 0.4 ***** ******** 0.2 **************** 0.0 ---------------- Multilevel CTGGCACGGTGCCAAG consensus T CATCA G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr1:181127031-181127531 + 49 1.77e-09 tatggagcac ctggcactgtgccaag cagcctagac chr14:95291759-95292259 + 40 1.77e-09 gactgtgttc ctggcactgtgccaag ggttgacgtg chr12:120646956-12064745 - 68 2.28e-09 TGCAAAGGGC TTGGCACTGTGCCAAG CATCTAGAAA chr19:48539554-48540054 - 57 1.06e-08 TACTCAGTGC CTGGCACAGTGCCAAG AGATCTGCAC chr15:74546102-74546602 - 68 1.06e-08 CACGCAGACG CTGGCCAGCTGCCAAG GCGGGGGCAG chr12:8243257-8243757 - 30 1.41e-08 CGCGCACCGC CTGGCCATGTGCCAAG ACATAGTCAA chr16:29943427-29943927 + 27 1.41e-08 ctgacctaac ttggccagctgccaag tttattattc chr1:230145424-230145924 - 31 2.70e-08 AAGGCCCCCA TTGGCACTATGCCAAG GTGGGTGGCT chr5:10288461-10288961 - 27 2.70e-08 CTAAGAGGGC TTGGCCCGGTGCCAGG TGGCTGCTTT chr10:61974516-61975016 - 44 2.70e-08 TTTAGACCGC TTGGCAAGCAGCCAAG CACTAGTCAT chr6:40882271-40882771 - 77 3.18e-08 ACCATCAG CTGGCCCGCTGCCAGG AATTGCTTGA chr5:145975508-145976008 - 18 3.18e-08 TCTGTTTCCT TTGGCTCTCTGCCAAG GGTCCAGTGG chr1:223731376-223731876 + 55 3.78e-08 GAGTACAGGC CTGGCACGGAGCCAGG AATGCACCAA chr13:98507161-98507661 - 25 4.42e-08 GTGTGAAGCG TTGGCCCTGTGCCAGG AGCCCGCAGG chr6:41278887-41279387 + 32 4.42e-08 gtgtcttaga ttggccctgagccaag cagagacgac chr12:121404691-12140519 - 30 5.30e-08 AGCTCTCTTT CTGGCACAGTGCCAGG ATTTTCAAAT chr22:29821358-29821858 - 13 5.30e-08 TTCCGGGGAC CTGGCATTCTGCCAAG CACTCCACAT chr5:73031870-73032370 + 65 6.25e-08 GAGTTGTCAA CTGGCACTGAGCCAGG CACGCAAAGC chr15:89383546-89384046 - 42 7.41e-08 CAAGAAGACG CTGGCTCTGAGCCAAG ACGCATCCCA chr2:227818167-227818667 - 46 7.41e-08 TCTCTAGCAC TTGGCACGGTGCCCAG CACATACTGA chr17:73474227-73474727 + 56 8.79e-08 TGACTCACAA CTGGCCACGTGCCAAG TTCGCTCTGG chr1:110176232-110176732 - 26 8.79e-08 TGCCACACAT CTGGCATGGAGCCAAG GCAGAAGCAG chr1:234523521-234524021 + 51 1.04e-07 TTTTTACAGG CTGGCAGGCTGCCAGG TTCCCTCGCC chr9:129639988-129640488 - 34 1.04e-07 AATGCGGCTG CTGGCACTGTGCCCAG AGCTAAGGGA chr18:48901926-48902426 - 18 1.04e-07 CGGGGCGGCC CTGGCCCGGGGCCAAG GCAAACAGGC chr2:62287846-62288346 + 48 1.04e-07 CCTCAGTGTC CTGGCACTGTGCCCAG TCTGTCTGGG chrX:13647559-13648059 - 31 1.22e-07 ATGATATGAC CTGGCATGCTGCCAGG AGGGCCTATT chr19:1361997-1362497 - 45 1.22e-07 CTTCGGAAGA CTGGCACTCTGCCAAT AATGTGATAT chr15:40763151-40763651 + 34 1.22e-07 CACTCCAGAC CTGGCACCCAGCCAAG CGCGCGGTTC chr11:86592844-86593344 - 49 1.22e-07 AGTCATTTTC CTGGCAGTGAGCCAAG GCCACAGTCA chr8:13276305-13276805 + 54 1.38e-07 AGGCGGCCTC CTGGCCCGCGGCCAAG CGCGCGCGGC chr1:221284028-221284528 + 51 1.38e-07 ttgtgggtag ttggcaaaatgccaag gaataagtca chr6:35181827-35182327 + 24 1.38e-07 ttcttgagcg ctggcaacgtgccagg ctccttgctg chr17:2264020-2264520 + 51 1.38e-07 CTTGTCTAAC TTGGCAAGGAGCCAAA GGAGGACTTT chr1:44327756-44328256 + 21 1.57e-07 GTCAGACTAC TTGGCCAGGAGCCAGG GAAGCTGGCT chr5:109468677-109469177 - 35 1.57e-07 CATGACAACG TTGGCTCCCTGCCAAG AACCACAGTG chr6:118660158-118660658 - 67 1.57e-07 GGCCCCTTAT CTGGCAATCTGCCAAC TCCCCCAGCT chr13:67224120-67224620 - 72 1.79e-07 GTCGCTTGTG CTGGCCAGGTGCCAAT CCCGCAGTAG chr10:87586164-87586664 - 51 2.03e-07 TAAGTAGGAT TTGGCAGGCTGCCAAA TTACCTAGGG chr11:114159934-11416043 - 47 2.03e-07 ACCCACAAGT CTGGCTCGCAGCCAGG CCTGGCCTGG chr6:37240130-37240630 - 59 2.31e-07 ACTGAGTTCT CTGGCCAACAGCCAAG AAAGAACTGT chr16:1271747-1272247 - 23 2.61e-07 CAGAGACCAG CTGGCAGGGTGCCAAC CATGCAGACG chrX:39755607-39756107 - 67 2.61e-07 AGCCTCCCAG CTGGCTGGGTGCCAGG GCTGGGCCTG chr17:21040149-21040649 + 76 2.61e-07 GGGCTCCTTG CTGGCACACTGCCAAC TGGCACTGC chr3:61894982-61895482 + 51 2.61e-07 CTTAGTTGGT CTGGCTGGGAGCCAAG GGATCTGGAA chr17:3004102-3004602 + 53 2.61e-07 GGGCCTTTCC TTGGCTCGGTGCCCAG CTGCCTGCTC chr4:186216656-186217156 + 52 2.61e-07 tccattttga ttggcacaaagccaag tgtttagtaa chr17:29042484-29042984 - 54 2.99e-07 CGCTAAGAAC TTGGCACGATGCCCAG AATAAGACCC chr1:80054126-80054626 - 69 3.42e-07 ACAGATAATA TTGGCTCCGAGCCAAG AATGAGCTCA chr21:16420024-16420524 - 48 3.42e-07 GAAGTTGATT TTGGCCAAGTGCCAAA ATCATGTGCA chr10:18607480-18607980 + 48 3.42e-07 atctggagCA TTGGCATGGGGCCaag aatacaggct chr8:30141564-30142064 - 38 3.42e-07 TAACCTGTAC TTGGCACTGTGCCCGG AGCCGTGACA chr5:32217734-32218234 + 62 3.42e-07 AAATGAGTAT TTGGCCAGCAGCCAAA ATGGAAAGAG chr5:10601227-10601727 - 28 3.84e-07 CTGGGAGGAG TTGGCACCCAGCCAGG TTGAGCCTCG chr21:34543871-34544371 - 34 3.84e-07 GGCAAGAATT CTGGCAAGTTGCCAAG TAAGGCAGCT chr13:112849465-11284996 + 44 4.30e-07 ttgttgagtt ttggctgtgtgccagg gattcagtgg chr1:12478147-12478647 + 57 4.30e-07 TGATTGCGGT CTGGCCCAATGCCAGG CCCAAGCCTG chr10:21724680-21725180 + 63 5.87e-07 GTTAGTAGAG CTGGCTTGCTGCCAAA AAGACAGTGC chr8:60807656-60808156 - 57 5.87e-07 GACCCCAAAT TTGGCCTTCTGCCAAA CCCACAGTGT chr6:80132940-80133440 - 27 6.49e-07 AGTTCAAGTG CTGGCACAATGCCAAC AGGGATGTTC chr1:234724153-234724653 - 43 8.01e-07 AATGAGGCCT CTGGCGGGCAGCCAAG TTACAAAGAA chr17:15828724-15829224 - 38 8.01e-07 CTGGGAGGCA CTGGCCCTGTACCAAG AGGGCTGCCT chr17:20646677-20647177 - 17 8.01e-07 CTGGGAGGCA CTGGCCCTGTACCAAG AGGGCTGCCT chr5:37717519-37718019 - 27 8.01e-07 TAGCAGAGAG CTGGCTACCTGCCAAA CCAAACAATC chr1:153880943-153881443 + 45 8.92e-07 TTTGCAGCCC CTGGCATGATGCCAAC ACTCAGTCAG chr5:125198493-125198993 + 32 8.92e-07 CACTGAACTT TTGGCAGGCAGCCAAC CAATCTCTGT chr1:31215941-31216441 - 40 8.92e-07 CCAGCCGCCT CTGGCCCAGGGCCAGG AAATGATTGT chr5:142223565-142224065 + 39 8.92e-07 agaagtagca ttggctgggtgccaat ggtgactcat chr1:232620479-232620979 + 32 9.83e-07 GCTATTCTGA CTGGCAAACTGCCAGT TTTAAACAAA chr1:235067771-235068271 - 52 9.83e-07 GTCATGACTT TTGGCTCCCAGCCAGG TGCGGTGGCA chr7:128523180-128523680 - 64 9.83e-07 TCCCCCATTC CTGGCATGCTGCCAGT CACTGGGGAG chr3:169657311-169657811 + 49 1.08e-06 TTGTACAGAA TTGGCAAGAAGCCAGA ACCCAGTCTC chr15:70062307-70062807 + 37 1.18e-06 CCGCCTCTGG CTGGCAGGCGGCCAAA AAACTAAGTA chr12:56636711-56637211 - 30 1.18e-06 GGAGGGCTTT TTGGCGCGGGGCCAGG GGTGGAGTAG chr1:43836442-43836942 + 45 1.18e-06 GGACTCAGAA CTGGCAGCCAGCCAGG GCTCACTCAG chr1:224204691-224205191 - 69 1.18e-06 AAGTGTGTGG CTGGCGCAGAGCCAGG CCCTCGGAGA chr5:81736013-81736513 + 48 1.18e-06 AAGCACAAAA TTGGCGCTATGCCAAA AGCCCTGTTT chr8:16825905-16826405 - 50 1.29e-06 GACTAGAAAT GTGGCACGGTGCCCAG AAATTAGGTC chr10:72364177-72364677 - 34 1.29e-06 CAAGGGCTCA TTGGCCCAGAGCCAGA GAAGGGGAGG chr7:132255818-132256318 - 21 1.53e-06 CCTCTTGTAC TTGGCTAGGAGCCAGC ATGATTTCCT chr17:58391416-58391916 + 47 1.83e-06 AATGTGTATC TTGGCCAGGTGCCCGA AATTCTTACC chr1:234997177-234997677 - 25 2.00e-06 TCCCTGGCAT CTGGCGCTGTGCCATG TCCCGTGGCG chr6:53927177-53927677 - 30 2.18e-06 CACTATCCTT CTGGCCTACTGCCAGA CACAAAACCT chr12:53501377-53501877 + 69 2.36e-06 TAGTTTGGGG TTGGCCCGGTTCCCAG ACTGCACTGG chr1:229221448-229221948 + 50 2.36e-06 CACATTTTCT TTGGCAATAGGCCAAC TATTTGTTCC chr22:41367037-41367537 + 35 2.56e-06 CGTGCTGCAG CTGGCGCAGGGCCAGG CCCGCCCTGC chr17:60641722-60642222 + 53 2.76e-06 AAAAAGGGAA TTGGCTGTCTGCCAGT TTCCAAGGCA chr2:170530187-170530687 + 20 2.97e-06 GCCAGTGCTC CTGGCCAGCTCCCAGG ACTCAGAGTG chr1:15886195-15886695 - 12 3.21e-06 CCTCCGGGAG GTGGCAAGCAGCCAAC TCAAACTGGA chr5:172437410-172437910 + 46 3.74e-06 CACACTGGAG GTGGCAGGCTGCCAAT ATTTTTTTCC chr1:203626482-203626982 - 51 3.74e-06 GAGGTGGGAC TTGGCGCGAGGCCAAA CCATTACTCT chr12:10721987-10722487 - 61 3.74e-06 CATGCTCCTG TTGGCCACATGCCAGC AAAGAGATGT chr17:80219346-80219846 - 42 4.04e-06 CTTCTGAGGT CTGGCGCCCTGCCAGT TGCCCTCTTT chr19:11344360-11344860 - 84 4.36e-06 C TGGGCCTGCTGCCAAG CTGTGGTGAC chr9:136109548-136110048 + 85 4.36e-06 CCGGCATGCC CGGGCACGCTGCCCAG chr6:85498822-85499322 + 28 5.78e-06 GATGTTTGGT TTGGCAAGAAGCCATA ACTGCTTGCC chr16:75305374-75305874 - 76 5.78e-06 TATTGCACC TTGACGCTGTGCCAAG TGCTGTTTTA chr6:45445728-45446228 - 22 5.78e-06 CATTTCCTTC TTGGCTATCTTCCCAG CTCCTGACAG chr1:230104614-230105114 - 16 6.20e-06 GTGACTCAGC CTGGCAAGGGCCCAGG TGCCTTCAGA chr15:69146027-69146527 + 34 6.64e-06 TTTCAACTTT TTGGCTCTCAGACAAG GATGGTCCTA chr5:139517839-139518339 + 35 7.12e-06 GTGACTTCAT CCGGCCCGGGGCCAAG GCCCGGCCTC chr1:230681497-230681997 + 46 7.63e-06 CCTCTCACTT TTGGCCATTTTCCAAG AAGAAATATG chr19:38831711-38832211 - 69 9.91e-06 GCTATTTTCT TTGGCCAGGTTCCCAC TGGGGCAAAG chr5:66757140-66757640 - 68 1.05e-05 CAGCCACAAG GTGGCAATGTGCCATA GACATTGAAC chr5:140295371-140295871 + 55 1.05e-05 CTAAAATGTG CTGGCAACACGCCAAA AGACTGGATG chr1:155983348-155983848 - 69 1.05e-05 TCAGTCCTTA TTGGCTTTAGGCCCAG AGGCCTTCTC chr17:20226750-20227250 - 36 1.12e-05 CTGGGAGGCA CTGGCCCTGCACCAAG AGAGCTGCCT chr1:29133552-29134052 - 48 1.61e-05 TGTTCTGTAA CTGGCAATCATCCCAT TTCCAACTAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:181127031-181127531 1.8e-09 48_[+1]_36 chr14:95291759-95292259 1.8e-09 39_[+1]_45 chr12:120646956-12064745 2.3e-09 67_[-1]_17 chr19:48539554-48540054 1.1e-08 56_[-1]_28 chr15:74546102-74546602 1.1e-08 67_[-1]_17 chr12:8243257-8243757 1.4e-08 29_[-1]_55 chr16:29943427-29943927 1.4e-08 26_[+1]_58 chr1:230145424-230145924 2.7e-08 30_[-1]_54 chr5:10288461-10288961 2.7e-08 26_[-1]_58 chr10:61974516-61975016 2.7e-08 43_[-1]_41 chr6:40882271-40882771 3.2e-08 76_[-1]_8 chr5:145975508-145976008 3.2e-08 17_[-1]_67 chr1:223731376-223731876 3.8e-08 54_[+1]_30 chr13:98507161-98507661 4.4e-08 24_[-1]_60 chr6:41278887-41279387 4.4e-08 31_[+1]_53 chr12:121404691-12140519 5.3e-08 29_[-1]_55 chr22:29821358-29821858 5.3e-08 12_[-1]_72 chr5:73031870-73032370 6.2e-08 64_[+1]_20 chr15:89383546-89384046 7.4e-08 41_[-1]_43 chr2:227818167-227818667 7.4e-08 45_[-1]_39 chr17:73474227-73474727 8.8e-08 55_[+1]_29 chr1:110176232-110176732 8.8e-08 25_[-1]_59 chr1:234523521-234524021 1e-07 50_[+1]_34 chr9:129639988-129640488 1e-07 33_[-1]_51 chr18:48901926-48902426 1e-07 17_[-1]_67 chr2:62287846-62288346 1e-07 47_[+1]_37 chrX:13647559-13648059 1.2e-07 30_[-1]_54 chr19:1361997-1362497 1.2e-07 44_[-1]_40 chr15:40763151-40763651 1.2e-07 33_[+1]_51 chr11:86592844-86593344 1.2e-07 48_[-1]_36 chr8:13276305-13276805 1.4e-07 53_[+1]_31 chr1:221284028-221284528 1.4e-07 50_[+1]_34 chr6:35181827-35182327 1.4e-07 23_[+1]_61 chr17:2264020-2264520 1.4e-07 50_[+1]_34 chr1:44327756-44328256 1.6e-07 20_[+1]_64 chr5:109468677-109469177 1.6e-07 34_[-1]_50 chr6:118660158-118660658 1.6e-07 66_[-1]_18 chr13:67224120-67224620 1.8e-07 71_[-1]_13 chr10:87586164-87586664 2e-07 50_[-1]_34 chr11:114159934-11416043 2e-07 46_[-1]_38 chr6:37240130-37240630 2.3e-07 58_[-1]_26 chr16:1271747-1272247 2.6e-07 22_[-1]_62 chrX:39755607-39756107 2.6e-07 66_[-1]_18 chr17:21040149-21040649 2.6e-07 75_[+1]_9 chr3:61894982-61895482 2.6e-07 50_[+1]_34 chr17:3004102-3004602 2.6e-07 52_[+1]_32 chr4:186216656-186217156 2.6e-07 51_[+1]_33 chr17:29042484-29042984 3e-07 53_[-1]_31 chr1:80054126-80054626 3.4e-07 68_[-1]_16 chr21:16420024-16420524 3.4e-07 47_[-1]_37 chr10:18607480-18607980 3.4e-07 47_[+1]_37 chr8:30141564-30142064 3.4e-07 37_[-1]_47 chr5:32217734-32218234 3.4e-07 61_[+1]_23 chr5:10601227-10601727 3.8e-07 27_[-1]_57 chr21:34543871-34544371 3.8e-07 33_[-1]_51 chr13:112849465-11284996 4.3e-07 43_[+1]_41 chr1:12478147-12478647 4.3e-07 56_[+1]_28 chr10:21724680-21725180 5.9e-07 62_[+1]_22 chr8:60807656-60808156 5.9e-07 56_[-1]_28 chr6:80132940-80133440 6.5e-07 26_[-1]_58 chr1:234724153-234724653 8e-07 42_[-1]_42 chr17:15828724-15829224 8e-07 37_[-1]_47 chr17:20646677-20647177 8e-07 16_[-1]_68 chr5:37717519-37718019 8e-07 26_[-1]_58 chr1:153880943-153881443 8.9e-07 44_[+1]_40 chr5:125198493-125198993 8.9e-07 31_[+1]_53 chr1:31215941-31216441 8.9e-07 39_[-1]_45 chr5:142223565-142224065 8.9e-07 38_[+1]_46 chr1:232620479-232620979 9.8e-07 31_[+1]_53 chr1:235067771-235068271 9.8e-07 51_[-1]_33 chr7:128523180-128523680 9.8e-07 63_[-1]_21 chr3:169657311-169657811 1.1e-06 48_[+1]_36 chr15:70062307-70062807 1.2e-06 36_[+1]_48 chr12:56636711-56637211 1.2e-06 29_[-1]_55 chr1:43836442-43836942 1.2e-06 44_[+1]_40 chr1:224204691-224205191 1.2e-06 68_[-1]_16 chr5:81736013-81736513 1.2e-06 47_[+1]_37 chr8:16825905-16826405 1.3e-06 49_[-1]_35 chr10:72364177-72364677 1.3e-06 33_[-1]_51 chr7:132255818-132256318 1.5e-06 20_[-1]_64 chr17:58391416-58391916 1.8e-06 46_[+1]_38 chr1:234997177-234997677 2e-06 24_[-1]_60 chr6:53927177-53927677 2.2e-06 29_[-1]_55 chr12:53501377-53501877 2.4e-06 68_[+1]_16 chr1:229221448-229221948 2.4e-06 49_[+1]_35 chr22:41367037-41367537 2.6e-06 34_[+1]_50 chr17:60641722-60642222 2.8e-06 52_[+1]_32 chr2:170530187-170530687 3e-06 19_[+1]_65 chr1:15886195-15886695 3.2e-06 11_[-1]_73 chr5:172437410-172437910 3.7e-06 45_[+1]_39 chr1:203626482-203626982 3.7e-06 50_[-1]_34 chr12:10721987-10722487 3.7e-06 60_[-1]_24 chr17:80219346-80219846 4e-06 41_[-1]_43 chr19:11344360-11344860 4.4e-06 83_[-1]_1 chr9:136109548-136110048 4.4e-06 84_[+1] chr6:85498822-85499322 5.8e-06 27_[+1]_57 chr16:75305374-75305874 5.8e-06 75_[-1]_9 chr6:45445728-45446228 5.8e-06 21_[-1]_63 chr1:230104614-230105114 6.2e-06 15_[-1]_69 chr15:69146027-69146527 6.6e-06 33_[+1]_51 chr5:139517839-139518339 7.1e-06 34_[+1]_50 chr1:230681497-230681997 7.6e-06 45_[+1]_39 chr19:38831711-38832211 9.9e-06 68_[-1]_16 chr5:66757140-66757640 1.1e-05 67_[-1]_17 chr5:140295371-140295871 1.1e-05 54_[+1]_30 chr1:155983348-155983848 1.1e-05 68_[-1]_16 chr17:20226750-20227250 1.1e-05 35_[-1]_49 chr1:29133552-29134052 1.6e-05 47_[-1]_37 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YTGGCMMKSTGCCAAG width=16 seqs=108 chr1:181127031-181127531 ( 49) CTGGCACTGTGCCAAG 1 chr14:95291759-95292259 ( 40) CTGGCACTGTGCCAAG 1 chr12:120646956-12064745 ( 68) TTGGCACTGTGCCAAG 1 chr19:48539554-48540054 ( 57) CTGGCACAGTGCCAAG 1 chr15:74546102-74546602 ( 68) CTGGCCAGCTGCCAAG 1 chr12:8243257-8243757 ( 30) CTGGCCATGTGCCAAG 1 chr16:29943427-29943927 ( 27) TTGGCCAGCTGCCAAG 1 chr1:230145424-230145924 ( 31) TTGGCACTATGCCAAG 1 chr5:10288461-10288961 ( 27) TTGGCCCGGTGCCAGG 1 chr10:61974516-61975016 ( 44) TTGGCAAGCAGCCAAG 1 chr6:40882271-40882771 ( 77) CTGGCCCGCTGCCAGG 1 chr5:145975508-145976008 ( 18) TTGGCTCTCTGCCAAG 1 chr1:223731376-223731876 ( 55) CTGGCACGGAGCCAGG 1 chr13:98507161-98507661 ( 25) TTGGCCCTGTGCCAGG 1 chr6:41278887-41279387 ( 32) TTGGCCCTGAGCCAAG 1 chr12:121404691-12140519 ( 30) CTGGCACAGTGCCAGG 1 chr22:29821358-29821858 ( 13) CTGGCATTCTGCCAAG 1 chr5:73031870-73032370 ( 65) CTGGCACTGAGCCAGG 1 chr15:89383546-89384046 ( 42) CTGGCTCTGAGCCAAG 1 chr2:227818167-227818667 ( 46) TTGGCACGGTGCCCAG 1 chr17:73474227-73474727 ( 56) CTGGCCACGTGCCAAG 1 chr1:110176232-110176732 ( 26) CTGGCATGGAGCCAAG 1 chr1:234523521-234524021 ( 51) CTGGCAGGCTGCCAGG 1 chr9:129639988-129640488 ( 34) CTGGCACTGTGCCCAG 1 chr18:48901926-48902426 ( 18) CTGGCCCGGGGCCAAG 1 chr2:62287846-62288346 ( 48) CTGGCACTGTGCCCAG 1 chrX:13647559-13648059 ( 31) CTGGCATGCTGCCAGG 1 chr19:1361997-1362497 ( 45) CTGGCACTCTGCCAAT 1 chr15:40763151-40763651 ( 34) CTGGCACCCAGCCAAG 1 chr11:86592844-86593344 ( 49) CTGGCAGTGAGCCAAG 1 chr8:13276305-13276805 ( 54) CTGGCCCGCGGCCAAG 1 chr1:221284028-221284528 ( 51) TTGGCAAAATGCCAAG 1 chr6:35181827-35182327 ( 24) CTGGCAACGTGCCAGG 1 chr17:2264020-2264520 ( 51) TTGGCAAGGAGCCAAA 1 chr1:44327756-44328256 ( 21) TTGGCCAGGAGCCAGG 1 chr5:109468677-109469177 ( 35) TTGGCTCCCTGCCAAG 1 chr6:118660158-118660658 ( 67) CTGGCAATCTGCCAAC 1 chr13:67224120-67224620 ( 72) CTGGCCAGGTGCCAAT 1 chr10:87586164-87586664 ( 51) TTGGCAGGCTGCCAAA 1 chr11:114159934-11416043 ( 47) CTGGCTCGCAGCCAGG 1 chr6:37240130-37240630 ( 59) CTGGCCAACAGCCAAG 1 chr16:1271747-1272247 ( 23) CTGGCAGGGTGCCAAC 1 chrX:39755607-39756107 ( 67) CTGGCTGGGTGCCAGG 1 chr17:21040149-21040649 ( 76) CTGGCACACTGCCAAC 1 chr3:61894982-61895482 ( 51) CTGGCTGGGAGCCAAG 1 chr17:3004102-3004602 ( 53) TTGGCTCGGTGCCCAG 1 chr4:186216656-186217156 ( 52) TTGGCACAAAGCCAAG 1 chr17:29042484-29042984 ( 54) TTGGCACGATGCCCAG 1 chr1:80054126-80054626 ( 69) TTGGCTCCGAGCCAAG 1 chr21:16420024-16420524 ( 48) TTGGCCAAGTGCCAAA 1 chr10:18607480-18607980 ( 48) TTGGCATGGGGCCAAG 1 chr8:30141564-30142064 ( 38) TTGGCACTGTGCCCGG 1 chr5:32217734-32218234 ( 62) TTGGCCAGCAGCCAAA 1 chr5:10601227-10601727 ( 28) TTGGCACCCAGCCAGG 1 chr21:34543871-34544371 ( 34) CTGGCAAGTTGCCAAG 1 chr13:112849465-11284996 ( 44) TTGGCTGTGTGCCAGG 1 chr1:12478147-12478647 ( 57) CTGGCCCAATGCCAGG 1 chr10:21724680-21725180 ( 63) CTGGCTTGCTGCCAAA 1 chr8:60807656-60808156 ( 57) TTGGCCTTCTGCCAAA 1 chr6:80132940-80133440 ( 27) CTGGCACAATGCCAAC 1 chr1:234724153-234724653 ( 43) CTGGCGGGCAGCCAAG 1 chr17:15828724-15829224 ( 38) CTGGCCCTGTACCAAG 1 chr17:20646677-20647177 ( 17) CTGGCCCTGTACCAAG 1 chr5:37717519-37718019 ( 27) CTGGCTACCTGCCAAA 1 chr1:153880943-153881443 ( 45) CTGGCATGATGCCAAC 1 chr5:125198493-125198993 ( 32) TTGGCAGGCAGCCAAC 1 chr1:31215941-31216441 ( 40) CTGGCCCAGGGCCAGG 1 chr5:142223565-142224065 ( 39) TTGGCTGGGTGCCAAT 1 chr1:232620479-232620979 ( 32) CTGGCAAACTGCCAGT 1 chr1:235067771-235068271 ( 52) TTGGCTCCCAGCCAGG 1 chr7:128523180-128523680 ( 64) CTGGCATGCTGCCAGT 1 chr3:169657311-169657811 ( 49) TTGGCAAGAAGCCAGA 1 chr15:70062307-70062807 ( 37) CTGGCAGGCGGCCAAA 1 chr12:56636711-56637211 ( 30) TTGGCGCGGGGCCAGG 1 chr1:43836442-43836942 ( 45) CTGGCAGCCAGCCAGG 1 chr1:224204691-224205191 ( 69) CTGGCGCAGAGCCAGG 1 chr5:81736013-81736513 ( 48) TTGGCGCTATGCCAAA 1 chr8:16825905-16826405 ( 50) GTGGCACGGTGCCCAG 1 chr10:72364177-72364677 ( 34) TTGGCCCAGAGCCAGA 1 chr7:132255818-132256318 ( 21) TTGGCTAGGAGCCAGC 1 chr17:58391416-58391916 ( 47) TTGGCCAGGTGCCCGA 1 chr1:234997177-234997677 ( 25) CTGGCGCTGTGCCATG 1 chr6:53927177-53927677 ( 30) CTGGCCTACTGCCAGA 1 chr12:53501377-53501877 ( 69) TTGGCCCGGTTCCCAG 1 chr1:229221448-229221948 ( 50) TTGGCAATAGGCCAAC 1 chr22:41367037-41367537 ( 35) CTGGCGCAGGGCCAGG 1 chr17:60641722-60642222 ( 53) TTGGCTGTCTGCCAGT 1 chr2:170530187-170530687 ( 20) CTGGCCAGCTCCCAGG 1 chr1:15886195-15886695 ( 12) GTGGCAAGCAGCCAAC 1 chr5:172437410-172437910 ( 46) GTGGCAGGCTGCCAAT 1 chr1:203626482-203626982 ( 51) TTGGCGCGAGGCCAAA 1 chr12:10721987-10722487 ( 61) TTGGCCACATGCCAGC 1 chr17:80219346-80219846 ( 42) CTGGCGCCCTGCCAGT 1 chr19:11344360-11344860 ( 84) TGGGCCTGCTGCCAAG 1 chr9:136109548-136110048 ( 85) CGGGCACGCTGCCCAG 1 chr6:85498822-85499322 ( 28) TTGGCAAGAAGCCATA 1 chr16:75305374-75305874 ( 76) TTGACGCTGTGCCAAG 1 chr6:45445728-45446228 ( 22) TTGGCTATCTTCCCAG 1 chr1:230104614-230105114 ( 16) CTGGCAAGGGCCCAGG 1 chr15:69146027-69146527 ( 34) TTGGCTCTCAGACAAG 1 chr5:139517839-139518339 ( 35) CCGGCCCGGGGCCAAG 1 chr1:230681497-230681997 ( 46) TTGGCCATTTTCCAAG 1 chr19:38831711-38832211 ( 69) TTGGCCAGGTTCCCAC 1 chr5:66757140-66757640 ( 68) GTGGCAATGTGCCATA 1 chr5:140295371-140295871 ( 55) CTGGCAACACGCCAAA 1 chr1:155983348-155983848 ( 69) TTGGCTTTAGGCCCAG 1 chr17:20226750-20227250 ( 36) CTGGCCCTGCACCAAG 1 chr1:29133552-29134052 ( 48) CTGGCAATCATCCCAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 10.0762 E= 3.5e-184 -1340 100 -283 88 -1340 -483 -383 204 -1340 -1340 192 -1340 -467 -1340 191 -1340 -1340 192 -1340 -1340 97 12 -166 -50 33 84 -103 -121 -77 -125 75 37 -77 49 84 -367 19 -383 -125 135 -309 -383 178 -235 -467 191 -1340 -1340 -1340 192 -1340 -1340 188 -103 -1340 -1340 148 -1340 25 -309 -58 -137 132 -150 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 108 E= 3.5e-184 0.000000 0.527778 0.037037 0.435185 0.000000 0.009259 0.018519 0.972222 0.000000 0.000000 1.000000 0.000000 0.009259 0.000000 0.990741 0.000000 0.000000 1.000000 0.000000 0.000000 0.462963 0.287037 0.083333 0.166667 0.296296 0.472222 0.129630 0.101852 0.138889 0.111111 0.444444 0.305556 0.138889 0.370370 0.472222 0.018519 0.268519 0.018519 0.111111 0.601852 0.027778 0.018519 0.907407 0.046296 0.009259 0.990741 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.870370 0.129630 0.000000 0.000000 0.657407 0.000000 0.314815 0.027778 0.157407 0.101852 0.657407 0.083333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YTGGCMMKSTGCCAAG MEME-1 regular expression -------------------------------------------------------------------------------- [CT]TGGC[AC][CA][GT][GC][TA]GCCA[AG]G -------------------------------------------------------------------------------- Time 366.43 secs. ******************************************************************************** ******************************************************************************** MOTIF HTBWTAAATAGTYY MEME-2 width = 14 sites = 96 llr = 996 E-value = 6.9e-067 ******************************************************************************** -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 Description -------------------------------------------------------------------------------- Simplified A 2214:aaa:a1:11 pos.-specific C 32311::::::234 probability G 1131::::::71:1 matrix T 35349:::9:2863 bits 2.1 ** * 1.9 *** * 1.7 ****** 1.5 ****** Relative 1.2 ****** Entropy 1.0 ****** * (15.0 bits) 0.8 ******** 0.6 ********* 0.4 ********** 0.2 ** *********** 0.0 -------------- Multilevel CTTTTAAATAGTTC consensus TCCA CT sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- -------------- chr5:44808448-44808948 + 11 1.23e-08 CTGCAGGATG TTTATAAATAGTTC CTGGCAAAGG chr9:385822-386322 + 58 2.55e-08 GCAGCCCAGA TTCTTAAATAGTTT TTAACTGTAG chr2:134919311-134919811 + 47 4.42e-08 GTCGTAGCCA TTGATAAATAGTTC CAGGGCCCTC chr6:25418680-25419180 + 35 5.40e-08 TCTCATCTGT CTCATAAATAGTTC TGGCTTGAGT chr17:40108310-40108810 - 43 6.63e-08 ATTCTGTCTC TTTTTAAATAGTCC ATTGATTCCA chr10:5861247-5861747 + 49 1.52e-07 GACTACCACT TATATAAATAGTTC TAACATAAGG chr20:32270580-32271080 + 58 2.16e-07 TCCTTGCATT CTAATAAATAGTTC CCTTTGCAGT chr1:214469215-214469715 + 29 2.16e-07 CATCTCCTTT CTGTTAAATAGTCT GGCTCCTGGA chr1:223819689-223820189 + 15 2.82e-07 aaggtctcta cccttaaatagttt acattctagt chr1:197180308-197180808 + 67 2.82e-07 AGATCCCTAC CTGTTAAATAGTTA TAGTAAAAGA chr8:140491598-140492098 + 27 2.82e-07 AACAAGCACT TACATAAATAGTTC CTTCCAAAGT chr12:57846932-57847432 - 53 3.30e-07 TCGGAGCGGC CTTTTAAATAGTTG GGAAGGGGGT chr17:27236696-27237196 + 50 3.30e-07 CCCAGTTAGC TTTGTAAATAGTTT TATGATAGTC chr19:18349515-18350015 + 78 3.68e-07 ATTACTCATT CTTTTAAATATTTT CATTTTgtt chr1:29133552-29134052 + 31 3.68e-07 TAGTAAGCTC TTGTTAAATAGTTG GAAATGGGAT chr15:38354223-38354723 + 12 4.27e-07 GAATTGATAA TTCTTAAATATTTC TCTTGGCTTC chr1:46522108-46522608 - 22 5.19e-07 GCCTAGCAGC TTATTAAATAGTCC ACAGTGAGTC chr1:223811646-223812146 - 76 5.19e-07 ACTGGATAAA TTATTAAATAGTCT CTCAATAGTG chr12:1605792-1606292 + 9 5.19e-07 TTCGCATG TTGATAAATATTTC AAAAGACAAG chr22:40070668-40071168 + 48 5.19e-07 aagtgggtag actataaatagttt catgtcagtt chr11:65961996-65962496 + 22 6.39e-07 TTTACCAGCT CTATTAAATAGTCT TTCTACGgga chr5:71830606-71831106 + 29 6.39e-07 ACAACCCAGC TCTATAAATAGTCC TGAGTGAGCC chr15:69146027-69146527 + 59 6.39e-07 GGATGGTCCT ACCTTAAATAGTTC TCTTTTTGGA chr5:271130-271630 - 19 6.39e-07 TTTCAGTTCT TGTATAAATAGTTT TGAGGTGAAT chr10:68900799-68901299 - 73 7.72e-07 TGCACTGATT AACATAAATAGTTC GGTTTATCTT chrX:73913448-73913948 + 28 7.72e-07 CCCAGAATAG CCTTTAAATAGTTA GCTTTCCCGT chr15:99306096-99306596 - 75 7.72e-07 TAGCCGAGTT CCTTTAAATAGTTA GGGATTTGCA chr1:151070353-151070853 + 16 9.16e-07 GTCCTCCGCC CCGTTAAATAGTCC TGCCTAGCAT chr10:116891095-11689159 - 33 1.05e-06 TCACCAGATT GTGTTAAATAGTCC AGCTGTTGCG chr11:85628101-85628601 + 48 1.05e-06 GGGAGCTAAG CTGATAAATAGTCA GGGAAGGAAA chr19:30648363-30648863 + 33 1.23e-06 CAGAGTATGA GTCATAAATAGTCC TTTTCACATT chr6:155177323-155177823 + 47 1.96e-06 GGTGCAGTAG AGCTTAAATAGTTT TAAGTTTCCA chr17:20646677-20647177 - 74 1.96e-06 AATCTGCACG CACTTAAATATTTC TCTTTCCTGC chr1:109149163-109149663 - 42 1.96e-06 CCTGCTAAGA TGATTAAATAGTTC AGTAGCTCTC chr17:78974979-78975479 + 71 2.23e-06 actatccctg ctgctaaatagttt atggattgtt chr13:112102298-11210279 - 46 2.73e-06 GCTGCTCTGT GCTATAAATAGTCC CCTGGTGGAT chr5:113217731-113218231 + 81 2.73e-06 CTGACCAGAC ACTGTAAATAGTTT AGTTTA chr3:8444313-8444813 + 50 2.73e-06 AGCGGACCAG TTGGTAAATATTTC ACCAGGCACA chr3:14125641-14126141 - 40 3.10e-06 ATGAATGTTG GGCTTAAATAGTTT CCCGAGAAAG chr1:84604285-84604785 - 6 3.10e-06 CTATCATTAG GAGTTAAATAGTCT TTCAG chr1:41003464-41003964 + 6 3.10e-06 taatg tatgtaaatagtct ctagtagtgc chr7:7681456-7681956 - 47 3.59e-06 GCTTGCTGGA TTTTTAAATAGTAG TATAAGGCTA chr8:120859583-120860083 - 78 4.13e-06 AGGTGCTAG GTATTAAATAGTTG AAAACACAGA chr4:53011921-53012421 + 17 4.13e-06 GGGTCAATGG ATCCTAAATAGTTT TCAGGTTCAA chr10:7433235-7433735 - 66 4.13e-06 GCTAAACATA ATATTAAATAGTCA GCAACATAAT chr17:7514636-7515136 + 35 5.13e-06 TTtactgatt gtcataaataattt ggaaaagtgt chr6:41767149-41767649 + 57 6.86e-06 CCAGTGAGGC CTGATAAATATTCG ACAAGGCCCT chr13:75437561-75438061 - 78 6.86e-06 GTTAATGCA TCTTCAAATAGTTC ACAGTGAACA chr11:106078021-10607852 + 63 7.68e-06 cttattctgc ctgttaaatatccc atcattCTCC chr17:7822581-7823081 + 27 7.68e-06 AGTGAATGAA TGAGTAAATAGTTT GTGCTTCTGT chr1:89719612-89720112 + 21 7.68e-06 AGCTCAGCTT TCAGTAAATAGTCT TATAGTAATG chrX:13647559-13648059 + 15 8.53e-06 ATTGTCACTG TTGATAAATAGGCC CTCCTGGCAG chr1:221284028-221284528 + 24 8.53e-06 atgagtctgt ctcataaatatcct ttgttgtggg chr12:54039773-54040273 + 61 9.39e-06 ATTCTCCTTC CCCTCAAATAGTTT GCCTCAGTTT chr5:66757140-66757640 + 27 9.39e-06 TTTACTAGGA CTATTAAATAGTAG CTGTTATGGA chr12:106779894-10678039 - 39 9.39e-06 AGGCTCCTCT AACATAAATAGCCT GCGATGTAAA chr5:93607813-93608313 - 50 1.02e-05 TGATCAAATG CCCACAAATAGTTC AGAACAACGG chr12:53501377-53501877 + 51 1.11e-05 GCTGCCTCCA GCTCTAAATAGTTT GGGGTTGGCC chr1:212488389-212488889 - 8 1.11e-05 TTGTTTGTTT TTGGTAAATAGTAA ACCTGGA chr12:2198154-2198654 - 41 1.21e-05 CGGAGGAACA CATTTAAATAGCCG CAGAGGGGAG chr5:124706624-124707124 - 55 1.34e-05 GCTCTCTCGC GTGATAAATAGCCA GGCTACTGCT chr5:88516519-88517019 + 9 1.34e-05 CCTTCATT CACATAAATATTAC TGGTCCCCTT chr4:38620878-38621378 - 38 1.47e-05 TTTAGAAGGC AAGTTAAATAATTA CGTGTTTTCA chr1:229221077-229221577 - 46 1.47e-05 AAGATGACGC AGTATAAATAGCCT TGGGAAGACT chr1:209884518-209885018 + 22 1.47e-05 AATTCCTAGA CTGTTAAATAGTGT AGTTTCTTTA chr10:114208330-11420883 - 82 1.59e-05 ACAGT GTCATAAATAGCAC AAGAGGGTGC chr3:55692915-55693415 - 7 1.72e-05 TCTGTCTGTG GATATAAATAGTAA TCCTTG chr12:56192886-56193386 + 14 1.72e-05 CAGGTTCTCA TATTTAAATATCTG GAGAGCCAAG chr14:65472189-65472689 - 74 2.01e-05 TGAAAACAGA ATAGTAAATAGCCT GAGTCTATGC chr1:173714639-173715139 - 64 2.01e-05 AGTAGTCCTA TTCTTAAATCGTTC CCGCAGGAAC chr8:42457990-42458490 - 41 2.01e-05 TAGTAGCATT CTGTTAAACATTTC TGTACATGTT chr17:28599396-28599896 + 76 2.18e-05 agtgagaaat actataaatatccc catttgtgac chr11:27201863-27202363 + 51 2.18e-05 cttctggaat ctcataaaaagttt ccaagctgct chr7:101882943-101883443 - 80 2.37e-05 ACCCCAT AACATAAATAACTT CATTTTTTAA chr12:69476176-69476676 + 49 2.37e-05 ATTAGCCAAC AAGATAAATAACTC GCCTTTGACA chr10:22912389-22912889 + 80 2.56e-05 AAGCAGATAA CTTTTAAATAACAC AGTGTGG chr17:70661149-70661649 - 14 2.75e-05 AGCCACAGAA AGGATAAATAGGTC GGGCATGTGG chr1:202222297-202222797 - 69 2.75e-05 AAAATGATTA CCTCTAAATATTTA CCCTGTGCAT chr6:27505535-27506035 - 59 2.75e-05 AGCCTGACTT CTCCCAAATAGTTT CCTTCTAATT chr19:47289313-47289813 + 63 2.75e-05 tggctcagtg gtgttaaatagcaa cttttactga chr1:227563165-227563665 + 25 3.16e-05 AATTGCCCAT TTTGTTAATAGTCT CATTCAACCC chr1:164787638-164788138 + 53 3.16e-05 ATTACCAAAT GGGTTAAATATCTT CATGGGCGCA chr17:58391416-58391916 - 3 3.16e-05 GTTAACTCAG CCTGTAAACAGTTC AA chr5:154461401-154461901 - 41 3.16e-05 TGATGGACCA ACTTTAAATAGCAA GACTCTACTG chr3:64995977-64996477 + 26 3.16e-05 TGATTTTCAA ACTGCAAATAGTTT AGCCCCACAT chr15:33126616-33127116 + 53 3.68e-05 AAAACTGATA CCCATAAATAACTG TGGCTGTATA chr10:6669253-6669753 + 62 3.97e-05 ATTCAAGTCA TCCGCAAATAGTCC ATTATATGGT chr4:185095932-185096432 - 15 4.51e-05 GATTGCCAAA TGAATTAATAGTTT ACAGCTATTG chr5:91314204-91314704 + 19 4.51e-05 TGGAGCCTTC TGTTTAAATAACTG CCAGAGCAGG chr8:133381828-133382328 - 20 4.80e-05 CTGATCCTGA CAGATAAACAGTCA CGTAGGAAAT chr12:71840362-71840862 + 74 4.80e-05 GCAGGAGTAT TTCATAAACAGCTG GAATCAACTG chr22:32473225-32473725 - 43 7.11e-05 CTTGATTCTG CAAATAAATATGTA TTGATTGCCT chr19:7257118-7257618 + 24 7.11e-05 CACAAGGGaa tttatcaatattcc ctgttatcta chr13:110593455-11059395 - 30 8.04e-05 ATTTACTTTT TAGTTTAATATTTG CCTGTAGTGC chrX:119943554-119944054 + 53 8.04e-05 TGTGTGCATC AATATAAATAAGCC GGTGGGGCAA chr17:21040149-21040649 + 18 8.56e-05 TGAAGTGATA CAGGTAAATAAGTC CCCCCAGTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:44808448-44808948 1.2e-08 10_[+2]_76 chr9:385822-386322 2.6e-08 57_[+2]_29 chr2:134919311-134919811 4.4e-08 46_[+2]_40 chr6:25418680-25419180 5.4e-08 34_[+2]_52 chr17:40108310-40108810 6.6e-08 42_[-2]_44 chr10:5861247-5861747 1.5e-07 48_[+2]_38 chr20:32270580-32271080 2.2e-07 57_[+2]_29 chr1:214469215-214469715 2.2e-07 28_[+2]_58 chr1:223819689-223820189 2.8e-07 14_[+2]_72 chr1:197180308-197180808 2.8e-07 66_[+2]_20 chr8:140491598-140492098 2.8e-07 26_[+2]_60 chr12:57846932-57847432 3.3e-07 52_[-2]_34 chr17:27236696-27237196 3.3e-07 49_[+2]_37 chr19:18349515-18350015 3.7e-07 77_[+2]_9 chr1:29133552-29134052 3.7e-07 30_[+2]_56 chr15:38354223-38354723 4.3e-07 11_[+2]_75 chr1:46522108-46522608 5.2e-07 21_[-2]_65 chr1:223811646-223812146 5.2e-07 75_[-2]_11 chr12:1605792-1606292 5.2e-07 8_[+2]_78 chr22:40070668-40071168 5.2e-07 47_[+2]_39 chr11:65961996-65962496 6.4e-07 21_[+2]_65 chr5:71830606-71831106 6.4e-07 28_[+2]_58 chr15:69146027-69146527 6.4e-07 58_[+2]_28 chr5:271130-271630 6.4e-07 18_[-2]_68 chr10:68900799-68901299 7.7e-07 72_[-2]_14 chrX:73913448-73913948 7.7e-07 27_[+2]_59 chr15:99306096-99306596 7.7e-07 74_[-2]_12 chr1:151070353-151070853 9.2e-07 15_[+2]_71 chr10:116891095-11689159 1.1e-06 32_[-2]_54 chr11:85628101-85628601 1.1e-06 47_[+2]_39 chr19:30648363-30648863 1.2e-06 32_[+2]_54 chr6:155177323-155177823 2e-06 46_[+2]_40 chr17:20646677-20647177 2e-06 73_[-2]_13 chr1:109149163-109149663 2e-06 41_[-2]_45 chr17:78974979-78975479 2.2e-06 70_[+2]_16 chr13:112102298-11210279 2.7e-06 45_[-2]_41 chr5:113217731-113218231 2.7e-06 80_[+2]_6 chr3:8444313-8444813 2.7e-06 49_[+2]_37 chr3:14125641-14126141 3.1e-06 39_[-2]_47 chr1:84604285-84604785 3.1e-06 5_[-2]_81 chr1:41003464-41003964 3.1e-06 5_[+2]_81 chr7:7681456-7681956 3.6e-06 46_[-2]_40 chr8:120859583-120860083 4.1e-06 77_[-2]_9 chr4:53011921-53012421 4.1e-06 16_[+2]_70 chr10:7433235-7433735 4.1e-06 65_[-2]_21 chr17:7514636-7515136 5.1e-06 34_[+2]_52 chr6:41767149-41767649 6.9e-06 56_[+2]_30 chr13:75437561-75438061 6.9e-06 77_[-2]_9 chr11:106078021-10607852 7.7e-06 62_[+2]_24 chr17:7822581-7823081 7.7e-06 26_[+2]_60 chr1:89719612-89720112 7.7e-06 20_[+2]_66 chrX:13647559-13648059 8.5e-06 14_[+2]_72 chr1:221284028-221284528 8.5e-06 23_[+2]_63 chr12:54039773-54040273 9.4e-06 60_[+2]_26 chr5:66757140-66757640 9.4e-06 26_[+2]_60 chr12:106779894-10678039 9.4e-06 38_[-2]_48 chr5:93607813-93608313 1e-05 49_[-2]_37 chr12:53501377-53501877 1.1e-05 50_[+2]_36 chr1:212488389-212488889 1.1e-05 7_[-2]_79 chr12:2198154-2198654 1.2e-05 40_[-2]_46 chr5:124706624-124707124 1.3e-05 54_[-2]_32 chr5:88516519-88517019 1.3e-05 8_[+2]_78 chr4:38620878-38621378 1.5e-05 37_[-2]_49 chr1:229221077-229221577 1.5e-05 45_[-2]_41 chr1:209884518-209885018 1.5e-05 21_[+2]_65 chr10:114208330-11420883 1.6e-05 81_[-2]_5 chr3:55692915-55693415 1.7e-05 6_[-2]_80 chr12:56192886-56193386 1.7e-05 13_[+2]_73 chr14:65472189-65472689 2e-05 73_[-2]_13 chr1:173714639-173715139 2e-05 63_[-2]_23 chr8:42457990-42458490 2e-05 40_[-2]_46 chr17:28599396-28599896 2.2e-05 75_[+2]_11 chr11:27201863-27202363 2.2e-05 50_[+2]_36 chr7:101882943-101883443 2.4e-05 79_[-2]_7 chr12:69476176-69476676 2.4e-05 48_[+2]_38 chr10:22912389-22912889 2.6e-05 79_[+2]_7 chr17:70661149-70661649 2.8e-05 13_[-2]_73 chr1:202222297-202222797 2.8e-05 68_[-2]_18 chr6:27505535-27506035 2.8e-05 58_[-2]_28 chr19:47289313-47289813 2.8e-05 62_[+2]_24 chr1:227563165-227563665 3.2e-05 24_[+2]_62 chr1:164787638-164788138 3.2e-05 52_[+2]_34 chr17:58391416-58391916 3.2e-05 2_[-2]_84 chr5:154461401-154461901 3.2e-05 40_[-2]_46 chr3:64995977-64996477 3.2e-05 25_[+2]_61 chr15:33126616-33127116 3.7e-05 52_[+2]_34 chr10:6669253-6669753 4e-05 61_[+2]_25 chr4:185095932-185096432 4.5e-05 14_[-2]_72 chr5:91314204-91314704 4.5e-05 18_[+2]_68 chr8:133381828-133382328 4.8e-05 19_[-2]_67 chr12:71840362-71840862 4.8e-05 73_[+2]_13 chr22:32473225-32473725 7.1e-05 42_[-2]_44 chr19:7257118-7257618 7.1e-05 23_[+2]_63 chr13:110593455-11059395 8e-05 29_[-2]_57 chrX:119943554-119944054 8e-05 52_[+2]_34 chr17:21040149-21040649 8.6e-05 17_[+2]_69 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF HTBWTAAATAGTYY width=14 seqs=96 chr5:44808448-44808948 ( 11) TTTATAAATAGTTC 1 chr9:385822-386322 ( 58) TTCTTAAATAGTTT 1 chr2:134919311-134919811 ( 47) TTGATAAATAGTTC 1 chr6:25418680-25419180 ( 35) CTCATAAATAGTTC 1 chr17:40108310-40108810 ( 43) TTTTTAAATAGTCC 1 chr10:5861247-5861747 ( 49) TATATAAATAGTTC 1 chr20:32270580-32271080 ( 58) CTAATAAATAGTTC 1 chr1:214469215-214469715 ( 29) CTGTTAAATAGTCT 1 chr1:223819689-223820189 ( 15) CCCTTAAATAGTTT 1 chr1:197180308-197180808 ( 67) CTGTTAAATAGTTA 1 chr8:140491598-140492098 ( 27) TACATAAATAGTTC 1 chr12:57846932-57847432 ( 53) CTTTTAAATAGTTG 1 chr17:27236696-27237196 ( 50) TTTGTAAATAGTTT 1 chr19:18349515-18350015 ( 78) CTTTTAAATATTTT 1 chr1:29133552-29134052 ( 31) TTGTTAAATAGTTG 1 chr15:38354223-38354723 ( 12) TTCTTAAATATTTC 1 chr1:46522108-46522608 ( 22) TTATTAAATAGTCC 1 chr1:223811646-223812146 ( 76) TTATTAAATAGTCT 1 chr12:1605792-1606292 ( 9) TTGATAAATATTTC 1 chr22:40070668-40071168 ( 48) ACTATAAATAGTTT 1 chr11:65961996-65962496 ( 22) CTATTAAATAGTCT 1 chr5:71830606-71831106 ( 29) TCTATAAATAGTCC 1 chr15:69146027-69146527 ( 59) ACCTTAAATAGTTC 1 chr5:271130-271630 ( 19) TGTATAAATAGTTT 1 chr10:68900799-68901299 ( 73) AACATAAATAGTTC 1 chrX:73913448-73913948 ( 28) CCTTTAAATAGTTA 1 chr15:99306096-99306596 ( 75) CCTTTAAATAGTTA 1 chr1:151070353-151070853 ( 16) CCGTTAAATAGTCC 1 chr10:116891095-11689159 ( 33) GTGTTAAATAGTCC 1 chr11:85628101-85628601 ( 48) CTGATAAATAGTCA 1 chr19:30648363-30648863 ( 33) GTCATAAATAGTCC 1 chr6:155177323-155177823 ( 47) AGCTTAAATAGTTT 1 chr17:20646677-20647177 ( 74) CACTTAAATATTTC 1 chr1:109149163-109149663 ( 42) TGATTAAATAGTTC 1 chr17:78974979-78975479 ( 71) CTGCTAAATAGTTT 1 chr13:112102298-11210279 ( 46) GCTATAAATAGTCC 1 chr5:113217731-113218231 ( 81) ACTGTAAATAGTTT 1 chr3:8444313-8444813 ( 50) TTGGTAAATATTTC 1 chr3:14125641-14126141 ( 40) GGCTTAAATAGTTT 1 chr1:84604285-84604785 ( 6) GAGTTAAATAGTCT 1 chr1:41003464-41003964 ( 6) TATGTAAATAGTCT 1 chr7:7681456-7681956 ( 47) TTTTTAAATAGTAG 1 chr8:120859583-120860083 ( 78) GTATTAAATAGTTG 1 chr4:53011921-53012421 ( 17) ATCCTAAATAGTTT 1 chr10:7433235-7433735 ( 66) ATATTAAATAGTCA 1 chr17:7514636-7515136 ( 35) GTCATAAATAATTT 1 chr6:41767149-41767649 ( 57) CTGATAAATATTCG 1 chr13:75437561-75438061 ( 78) TCTTCAAATAGTTC 1 chr11:106078021-10607852 ( 63) CTGTTAAATATCCC 1 chr17:7822581-7823081 ( 27) TGAGTAAATAGTTT 1 chr1:89719612-89720112 ( 21) TCAGTAAATAGTCT 1 chrX:13647559-13648059 ( 15) TTGATAAATAGGCC 1 chr1:221284028-221284528 ( 24) CTCATAAATATCCT 1 chr12:54039773-54040273 ( 61) CCCTCAAATAGTTT 1 chr5:66757140-66757640 ( 27) CTATTAAATAGTAG 1 chr12:106779894-10678039 ( 39) AACATAAATAGCCT 1 chr5:93607813-93608313 ( 50) CCCACAAATAGTTC 1 chr12:53501377-53501877 ( 51) GCTCTAAATAGTTT 1 chr1:212488389-212488889 ( 8) TTGGTAAATAGTAA 1 chr12:2198154-2198654 ( 41) CATTTAAATAGCCG 1 chr5:124706624-124707124 ( 55) GTGATAAATAGCCA 1 chr5:88516519-88517019 ( 9) CACATAAATATTAC 1 chr4:38620878-38621378 ( 38) AAGTTAAATAATTA 1 chr1:229221077-229221577 ( 46) AGTATAAATAGCCT 1 chr1:209884518-209885018 ( 22) CTGTTAAATAGTGT 1 chr10:114208330-11420883 ( 82) GTCATAAATAGCAC 1 chr3:55692915-55693415 ( 7) GATATAAATAGTAA 1 chr12:56192886-56193386 ( 14) TATTTAAATATCTG 1 chr14:65472189-65472689 ( 74) ATAGTAAATAGCCT 1 chr1:173714639-173715139 ( 64) TTCTTAAATCGTTC 1 chr8:42457990-42458490 ( 41) CTGTTAAACATTTC 1 chr17:28599396-28599896 ( 76) ACTATAAATATCCC 1 chr11:27201863-27202363 ( 51) CTCATAAAAAGTTT 1 chr7:101882943-101883443 ( 80) AACATAAATAACTT 1 chr12:69476176-69476676 ( 49) AAGATAAATAACTC 1 chr10:22912389-22912889 ( 80) CTTTTAAATAACAC 1 chr17:70661149-70661649 ( 14) AGGATAAATAGGTC 1 chr1:202222297-202222797 ( 69) CCTCTAAATATTTA 1 chr6:27505535-27506035 ( 59) CTCCCAAATAGTTT 1 chr19:47289313-47289813 ( 63) GTGTTAAATAGCAA 1 chr1:227563165-227563665 ( 25) TTTGTTAATAGTCT 1 chr1:164787638-164788138 ( 53) GGGTTAAATATCTT 1 chr17:58391416-58391916 ( 3) CCTGTAAACAGTTC 1 chr5:154461401-154461901 ( 41) ACTTTAAATAGCAA 1 chr3:64995977-64996477 ( 26) ACTGCAAATAGTTT 1 chr15:33126616-33127116 ( 53) CCCATAAATAACTG 1 chr10:6669253-6669753 ( 62) TCCGCAAATAGTCC 1 chr4:185095932-185096432 ( 15) TGAATTAATAGTTT 1 chr5:91314204-91314704 ( 19) TGTTTAAATAACTG 1 chr8:133381828-133382328 ( 20) CAGATAAACAGTCA 1 chr12:71840362-71840862 ( 74) TTCATAAACAGCTG 1 chr22:32473225-32473725 ( 43) CAAATAAATATGTA 1 chr19:7257118-7257618 ( 24) TTTATCAATATTCC 1 chr13:110593455-11059395 ( 30) TAGTTTAATATTTG 1 chrX:119943554-119944054 ( 53) AATATAAATAAGCC 1 chr17:21040149-21040649 ( 18) CAGGTAAATAAGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 14 n= 52200 bayes= 10.1851 E= 6.9e-067 -33 38 -96 50 -25 -27 -134 102 -80 4 4 45 71 -234 -96 86 -1323 -208 -1323 199 202 -466 -1323 -292 208 -1323 -1323 -1323 208 -1323 -1323 -1323 -450 -266 -1323 201 207 -466 -1323 -1323 -133 -1323 147 -41 -1323 -42 -234 167 -133 24 -466 130 -69 55 -108 54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 14 nsites= 96 E= 6.9e-067 0.187500 0.343750 0.135417 0.333333 0.197917 0.218750 0.104167 0.479167 0.135417 0.270833 0.270833 0.322917 0.385417 0.052083 0.135417 0.427083 0.000000 0.062500 0.000000 0.937500 0.958333 0.010417 0.000000 0.031250 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.010417 0.041667 0.000000 0.947917 0.989583 0.010417 0.000000 0.000000 0.093750 0.000000 0.729167 0.177083 0.000000 0.197917 0.052083 0.750000 0.093750 0.312500 0.010417 0.583333 0.145833 0.385417 0.125000 0.343750 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif HTBWTAAATAGTYY MEME-2 regular expression -------------------------------------------------------------------------------- [CT][TC][TCG][TA]TAAATAGT[TC][CT] -------------------------------------------------------------------------------- Time 691.67 secs. ******************************************************************************** ******************************************************************************** MOTIF KGGYAATCADTT MEME-3 width = 12 sites = 70 llr = 736 E-value = 1.5e-038 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1:1:6a::a4:: pos.-specific C :::53::a::22 probability G 5a91:::::3:2 matrix T 3::41:a::385 bits 2.1 ** * 1.9 * **** 1.7 * **** 1.5 ** **** * Relative 1.2 ** **** * Entropy 1.0 ** **** * (15.2 bits) 0.8 ** **** * 0.6 ** ***** * 0.4 ************ 0.2 ************ 0.0 ------------ Multilevel GGGCAATCAATT consensus T TC G C sequence T G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr3:55692915-55693415 + 72 5.23e-08 TTTAGGATTA GGGCAATCAATT TCCTAGGACA chr3:37197613-37198113 - 16 5.23e-08 GGGATAGGAA GGGCAATCAATT AATTTTTCCC chr3:177714454-177714954 + 78 2.57e-07 GCCTAAAGTA GGGCAATCAGTT TAGTATGCAC chr7:65872571-65873071 - 55 2.57e-07 CCTCTGGGGA TGGCAATCAATT GCCATCCTTT chr1:83857109-83857609 - 73 3.97e-07 AAAAAATCAG TGGTAATCAATT TGAACAGTAC chrX:13658620-13659120 + 73 5.55e-07 GTTTCACAAA GGGCCATCAATT CAGGATCTTA chr18:57819866-57820366 - 8 6.96e-07 GGGACAGCAC TGGTAATCAGTT TTTCCTG chr5:174371533-174372033 + 21 6.96e-07 GGGGACCTGC TGGTAATCATTT GCAGCAGCCA chr1:167797015-167797515 + 63 6.96e-07 GAGGAGGTCG TGGTAATCATTT AATGCTGACT chr22:37330363-37330863 + 57 8.13e-07 TCTGCAGCTT GGGCAATCAATC GGTCGCCATG chr1:110338807-110339307 - 39 1.09e-06 TTGGGAGGTC GGGCCATCAGTT TCGGCGTTTT chr10:21292699-21293199 + 44 1.25e-06 GCAAAGATTT GGGTCATCATTT TTTAAACGAC chr5:177546330-177546830 + 37 1.65e-06 ACTGATGAGA GGGCAATCAGTG AGAAGAATCT chr6:53927177-53927677 + 76 1.65e-06 CTCTGAGAGT GGGCAATCATTG TGACAAGCAT chr16:66406446-66406946 + 61 1.65e-06 CCGGGCATCC TGGCAATCAATG GACCGCAGGT chr2:27032421-27032921 + 41 1.65e-06 agcgCGGCCC TGGcaatcaatc aatcaattga chr6:40882271-40882771 + 57 1.65e-06 CCAGGCAGAG TGGCAATCAATC AAGCAATTCC chr16:84138675-84139175 + 72 2.07e-06 GCAGTGTAAA GGGCAATCAACT CAAATAGAAA chr2:55014920-55015420 - 49 2.07e-06 TCCATGAACT GGGCAATCAACT GTAGACTACG chr15:66498750-66499250 + 16 2.07e-06 ACTTCTCAAG AGGTAATCAATT TTACTGCAGT chr10:124917810-12491831 - 38 2.23e-06 TTACAGAAAA GGGTAATCAACT GACTGAAATA chr3:138082324-138082824 - 3 2.33e-06 GACATGAATG TGGTCATCAGTT TT chr5:37668444-37668944 + 83 2.33e-06 AGCTTCCAGC TGGTCATCAGTT AGAGTC chr5:95861477-95861977 - 82 2.33e-06 CATTCGA TGGTCATCAGTT TTATCAGGGG chr4:185095932-185096432 + 31 2.83e-06 TTAATTCATT TGGCAATCAGTG aaaaaaaaaa chr9:129334002-129334502 + 31 3.55e-06 TGATCCAGGT TGGTAATCAGTG GCCGGGCCTG chr1:109438736-109439236 - 9 3.55e-06 TCAGCAGTCG GGGTCATCAATG AACTATTC chr2:95333888-95334388 - 59 3.55e-06 CCACTCACAC GGGTCATCAATC CTCATGTTTT chr1:164787638-164788138 - 38 3.55e-06 TTAACCCATT TGGTAATCATTC TTACAGAAAG chr17:68462821-68463321 + 30 3.55e-06 GTGCAGGGAG TGGTAATCATTC TCTAGAATCA chr3:126357724-126358224 + 59 4.34e-06 GCTTTCAGCA GGACAATCAGTT ACCCTCCGGA chr1:76759959-76760459 - 71 5.41e-06 ACTCTCGCGG TGGTCATCAATG CCCTGTTAAT chr2:170530187-170530687 + 46 5.41e-06 ACTCAGAGTG GGGCTATCATTT TTGTTTGCTT chr17:40108310-40108810 + 67 5.41e-06 GAGACAGAAT GGATAATCAGTT AGAGACCGAC chr7:7640805-7641305 + 65 5.41e-06 ATGGGCAGCG GGGTCATCAGTG ATCTTGATCA chr13:77329164-77329664 - 32 5.41e-06 AACGCTGCAC TGGCTATCAATT TTGAGGAGAG chr1:23544613-23545113 + 20 7.79e-06 CCAGGAAAAG AGGTCATCATTT TTGTTCCTCT chr11:27201863-27202363 - 24 7.79e-06 AGAAGCAGCA AGGTCATCAGTT TTATGGCCAT chr1:225653599-225654099 + 39 7.79e-06 ATGGAAAATA TGGTCATCATTG TTCCCTTCGC chr6:37171929-37172429 + 44 8.38e-06 TGCGGAGGGT GGGTCATCATCT GAGCGGCTTA chr7:66183538-66184038 - 15 8.38e-06 TGACCAGTGT GGACAATCAATC AACAACTGTA chr18:48446553-48447053 + 75 8.38e-06 GCGCCTGTTA AGGCAATCAGTC AGGGAGAAGG chr2:25991507-25992007 + 60 9.56e-06 TCCAATTTCT GGGCTATCAATC GTTATGCAAT chr12:108631838-10863233 - 37 9.56e-06 CAGAGGAGCT GGGGAATCAATC ATCCGAGAAC chr12:50247119-50247619 - 49 9.56e-06 TCAGTTCCCA GGGCAATCATCC AGAGACAGAG chr12:38316449-38316949 + 24 1.04e-05 GTGATGGAGA GGGTAATCATCC GGTCCGTTAT chr12:34022168-34022668 + 12 1.04e-05 GCGATTGAGA GGGTAATCATCC GGTCCGTTAT chr19:18364963-18365463 + 74 1.10e-05 ATGCACGTTC TGGAAATCAGTT TCTATTTTGG chr14:91380731-91381231 - 76 1.10e-05 CTTGCAGGAA GGGGCATCAGTT TGGCACTTAG chrX:119622844-119623344 + 64 1.38e-05 GCAATAGCTG CGGCAATCAGTT TGGTGACTAA chr5:32217734-32218234 + 13 1.38e-05 TACCACGCCG GGGCAATCACTT CTGTGTCCTA chr2:171703575-171704075 - 74 1.38e-05 GTCTCTTCTA AGGTCATCAATG ATACTCAGTA chr17:43671068-43671568 + 82 1.52e-05 AGCTTGAGAT GGATAATCAACT CCTCCTA chr15:38354223-38354723 + 40 1.56e-05 GGCTTCAAAA GGGACATCATTT GATTTCTGAA chr12:54039773-54040273 - 46 1.90e-05 TTGAGGGGAA GGAGAATCAATT ATCACAGGAA chr14:65472189-65472689 + 44 1.90e-05 tcaacaggag ggacaatcatct aagtgatagc chr5:76838792-76839292 - 40 1.90e-05 CATTTAAGTG GGACAATCATCT CAGTGAAGTT chr12:71840362-71840862 + 21 2.07e-05 TGCATAGTTA GGGCTATCAGCT TTATGATATG chr5:54243403-54243903 - 24 2.07e-05 GTTCATTACA TGGTCATCAATA ACCATTTCCT chr8:30382234-30382734 + 57 2.12e-05 CTGCCAGTTA AGGCAATCAATA CATCCAAACA chr4:98929385-98929885 + 84 2.12e-05 AGAGTCGTTT AGGCAATCAACC CTCCC chr5:149959256-149959756 - 10 2.47e-05 TTCACCTCAA TGGGCATCAATG TTTTCACCT chr17:7514636-7515136 - 84 2.64e-05 ATTAT GGGTGATCATTT TTCTCCCTCT chr14:24296730-24297230 + 43 2.64e-05 AGAACTGAGA AGACAATCAATC CTAGGAGAGC chr19:41859482-41859982 - 80 2.64e-05 GAAGAAATG TGGCTATCATCT TCCGTCCTTC chr4:82374296-82374796 - 55 2.77e-05 AGAGTAGCTG CGGCAATCAGTG CGCGCGCGGT chr3:186806162-186806662 - 66 3.19e-05 GGCGACTGTG GGGACATCAGTG ATCGTAAGTC chr13:41996010-41996510 + 79 3.87e-05 ACTTAAGGGT GGATAATCAGTA GCTTCTACAG chr7:140165420-140165920 + 77 3.87e-05 atcaactgtc ggggtatcaatg cttgtgttca chr6:118800479-118800979 + 87 5.21e-05 TCAGCCGTTA GAGCAATCATTG TT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:55692915-55693415 5.2e-08 71_[+3]_17 chr3:37197613-37198113 5.2e-08 15_[-3]_73 chr3:177714454-177714954 2.6e-07 77_[+3]_11 chr7:65872571-65873071 2.6e-07 54_[-3]_34 chr1:83857109-83857609 4e-07 72_[-3]_16 chrX:13658620-13659120 5.5e-07 72_[+3]_16 chr18:57819866-57820366 7e-07 7_[-3]_81 chr5:174371533-174372033 7e-07 20_[+3]_68 chr1:167797015-167797515 7e-07 62_[+3]_26 chr22:37330363-37330863 8.1e-07 56_[+3]_32 chr1:110338807-110339307 1.1e-06 38_[-3]_50 chr10:21292699-21293199 1.3e-06 43_[+3]_45 chr5:177546330-177546830 1.7e-06 36_[+3]_52 chr6:53927177-53927677 1.7e-06 75_[+3]_13 chr16:66406446-66406946 1.7e-06 60_[+3]_28 chr2:27032421-27032921 1.7e-06 40_[+3]_48 chr6:40882271-40882771 1.7e-06 56_[+3]_32 chr16:84138675-84139175 2.1e-06 71_[+3]_17 chr2:55014920-55015420 2.1e-06 48_[-3]_40 chr15:66498750-66499250 2.1e-06 15_[+3]_73 chr10:124917810-12491831 2.2e-06 37_[-3]_51 chr3:138082324-138082824 2.3e-06 2_[-3]_86 chr5:37668444-37668944 2.3e-06 82_[+3]_6 chr5:95861477-95861977 2.3e-06 81_[-3]_7 chr4:185095932-185096432 2.8e-06 30_[+3]_58 chr9:129334002-129334502 3.6e-06 30_[+3]_58 chr1:109438736-109439236 3.6e-06 8_[-3]_80 chr2:95333888-95334388 3.6e-06 58_[-3]_30 chr1:164787638-164788138 3.6e-06 37_[-3]_51 chr17:68462821-68463321 3.6e-06 29_[+3]_59 chr3:126357724-126358224 4.3e-06 58_[+3]_30 chr1:76759959-76760459 5.4e-06 70_[-3]_18 chr2:170530187-170530687 5.4e-06 45_[+3]_43 chr17:40108310-40108810 5.4e-06 66_[+3]_22 chr7:7640805-7641305 5.4e-06 64_[+3]_24 chr13:77329164-77329664 5.4e-06 31_[-3]_57 chr1:23544613-23545113 7.8e-06 19_[+3]_69 chr11:27201863-27202363 7.8e-06 23_[-3]_65 chr1:225653599-225654099 7.8e-06 38_[+3]_50 chr6:37171929-37172429 8.4e-06 43_[+3]_45 chr7:66183538-66184038 8.4e-06 14_[-3]_74 chr18:48446553-48447053 8.4e-06 74_[+3]_14 chr2:25991507-25992007 9.6e-06 59_[+3]_29 chr12:108631838-10863233 9.6e-06 36_[-3]_52 chr12:50247119-50247619 9.6e-06 48_[-3]_40 chr12:38316449-38316949 1e-05 23_[+3]_65 chr12:34022168-34022668 1e-05 11_[+3]_77 chr19:18364963-18365463 1.1e-05 73_[+3]_15 chr14:91380731-91381231 1.1e-05 75_[-3]_13 chrX:119622844-119623344 1.4e-05 63_[+3]_25 chr5:32217734-32218234 1.4e-05 12_[+3]_76 chr2:171703575-171704075 1.4e-05 73_[-3]_15 chr17:43671068-43671568 1.5e-05 81_[+3]_7 chr15:38354223-38354723 1.6e-05 39_[+3]_49 chr12:54039773-54040273 1.9e-05 45_[-3]_43 chr14:65472189-65472689 1.9e-05 43_[+3]_45 chr5:76838792-76839292 1.9e-05 39_[-3]_49 chr12:71840362-71840862 2.1e-05 20_[+3]_68 chr5:54243403-54243903 2.1e-05 23_[-3]_65 chr8:30382234-30382734 2.1e-05 56_[+3]_32 chr4:98929385-98929885 2.1e-05 83_[+3]_5 chr5:149959256-149959756 2.5e-05 9_[-3]_79 chr17:7514636-7515136 2.6e-05 83_[-3]_5 chr14:24296730-24297230 2.6e-05 42_[+3]_46 chr19:41859482-41859982 2.6e-05 79_[-3]_9 chr4:82374296-82374796 2.8e-05 54_[-3]_34 chr3:186806162-186806662 3.2e-05 65_[-3]_23 chr13:41996010-41996510 3.9e-05 78_[+3]_10 chr7:140165420-140165920 3.9e-05 76_[+3]_12 chr6:118800479-118800979 5.2e-05 86_[+3]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGGYAATCADTT width=12 seqs=70 chr3:55692915-55693415 ( 72) GGGCAATCAATT 1 chr3:37197613-37198113 ( 16) GGGCAATCAATT 1 chr3:177714454-177714954 ( 78) GGGCAATCAGTT 1 chr7:65872571-65873071 ( 55) TGGCAATCAATT 1 chr1:83857109-83857609 ( 73) TGGTAATCAATT 1 chrX:13658620-13659120 ( 73) GGGCCATCAATT 1 chr18:57819866-57820366 ( 8) TGGTAATCAGTT 1 chr5:174371533-174372033 ( 21) TGGTAATCATTT 1 chr1:167797015-167797515 ( 63) TGGTAATCATTT 1 chr22:37330363-37330863 ( 57) GGGCAATCAATC 1 chr1:110338807-110339307 ( 39) GGGCCATCAGTT 1 chr10:21292699-21293199 ( 44) GGGTCATCATTT 1 chr5:177546330-177546830 ( 37) GGGCAATCAGTG 1 chr6:53927177-53927677 ( 76) GGGCAATCATTG 1 chr16:66406446-66406946 ( 61) TGGCAATCAATG 1 chr2:27032421-27032921 ( 41) TGGCAATCAATC 1 chr6:40882271-40882771 ( 57) TGGCAATCAATC 1 chr16:84138675-84139175 ( 72) GGGCAATCAACT 1 chr2:55014920-55015420 ( 49) GGGCAATCAACT 1 chr15:66498750-66499250 ( 16) AGGTAATCAATT 1 chr10:124917810-12491831 ( 38) GGGTAATCAACT 1 chr3:138082324-138082824 ( 3) TGGTCATCAGTT 1 chr5:37668444-37668944 ( 83) TGGTCATCAGTT 1 chr5:95861477-95861977 ( 82) TGGTCATCAGTT 1 chr4:185095932-185096432 ( 31) TGGCAATCAGTG 1 chr9:129334002-129334502 ( 31) TGGTAATCAGTG 1 chr1:109438736-109439236 ( 9) GGGTCATCAATG 1 chr2:95333888-95334388 ( 59) GGGTCATCAATC 1 chr1:164787638-164788138 ( 38) TGGTAATCATTC 1 chr17:68462821-68463321 ( 30) TGGTAATCATTC 1 chr3:126357724-126358224 ( 59) GGACAATCAGTT 1 chr1:76759959-76760459 ( 71) TGGTCATCAATG 1 chr2:170530187-170530687 ( 46) GGGCTATCATTT 1 chr17:40108310-40108810 ( 67) GGATAATCAGTT 1 chr7:7640805-7641305 ( 65) GGGTCATCAGTG 1 chr13:77329164-77329664 ( 32) TGGCTATCAATT 1 chr1:23544613-23545113 ( 20) AGGTCATCATTT 1 chr11:27201863-27202363 ( 24) AGGTCATCAGTT 1 chr1:225653599-225654099 ( 39) TGGTCATCATTG 1 chr6:37171929-37172429 ( 44) GGGTCATCATCT 1 chr7:66183538-66184038 ( 15) GGACAATCAATC 1 chr18:48446553-48447053 ( 75) AGGCAATCAGTC 1 chr2:25991507-25992007 ( 60) GGGCTATCAATC 1 chr12:108631838-10863233 ( 37) GGGGAATCAATC 1 chr12:50247119-50247619 ( 49) GGGCAATCATCC 1 chr12:38316449-38316949 ( 24) GGGTAATCATCC 1 chr12:34022168-34022668 ( 12) GGGTAATCATCC 1 chr19:18364963-18365463 ( 74) TGGAAATCAGTT 1 chr14:91380731-91381231 ( 76) GGGGCATCAGTT 1 chrX:119622844-119623344 ( 64) CGGCAATCAGTT 1 chr5:32217734-32218234 ( 13) GGGCAATCACTT 1 chr2:171703575-171704075 ( 74) AGGTCATCAATG 1 chr17:43671068-43671568 ( 82) GGATAATCAACT 1 chr15:38354223-38354723 ( 40) GGGACATCATTT 1 chr12:54039773-54040273 ( 46) GGAGAATCAATT 1 chr14:65472189-65472689 ( 44) GGACAATCATCT 1 chr5:76838792-76839292 ( 40) GGACAATCATCT 1 chr12:71840362-71840862 ( 21) GGGCTATCAGCT 1 chr5:54243403-54243903 ( 24) TGGTCATCAATA 1 chr8:30382234-30382734 ( 57) AGGCAATCAATA 1 chr4:98929385-98929885 ( 84) AGGCAATCAACC 1 chr5:149959256-149959756 ( 10) TGGGCATCAATG 1 chr17:7514636-7515136 ( 84) GGGTGATCATTT 1 chr14:24296730-24297230 ( 43) AGACAATCAATC 1 chr19:41859482-41859982 ( 80) TGGCTATCATCT 1 chr4:82374296-82374796 ( 55) CGGCAATCAGTG 1 chr3:186806162-186806662 ( 66) GGGACATCAGTG 1 chr13:41996010-41996510 ( 79) GGATAATCAGTA 1 chr7:140165420-140165920 ( 77) GGGGTATCAATG 1 chr6:118800479-118800979 ( 87) GAGCAATCATTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 9.67599 E= 1.5e-038 -105 -321 104 41 -404 -1277 190 -1277 -88 -1277 172 -1277 -246 84 -188 81 138 11 -420 -146 208 -1277 -1277 -1277 -1277 -1277 -1277 208 -1277 192 -1277 -1277 208 -1277 -1277 -1277 81 -420 18 20 -1277 -51 -1277 179 -246 -30 -30 116 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 70 E= 1.5e-038 0.114286 0.028571 0.542857 0.314286 0.014286 0.000000 0.985714 0.000000 0.128571 0.000000 0.871429 0.000000 0.042857 0.471429 0.071429 0.414286 0.614286 0.285714 0.014286 0.085714 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.414286 0.014286 0.300000 0.271429 0.000000 0.185714 0.000000 0.814286 0.042857 0.214286 0.214286 0.528571 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGGYAATCADTT MEME-3 regular expression -------------------------------------------------------------------------------- [GT]GG[CT][AC]ATCA[AGT]T[TCG] -------------------------------------------------------------------------------- Time 982.73 secs. ******************************************************************************** ******************************************************************************** MOTIF GCGCCCYCTNSYGGCS MEME-4 width = 16 sites = 76 llr = 780 E-value = 2.9e-027 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::2:::3:1::1: pos.-specific C 37:9975912351185 probability G 7:911121236:98:4 matrix T :3::::3:72:4:211 bits 2.1 1.9 1.7 * 1.5 ** * * Relative 1.2 *** * * Entropy 1.0 **** ** * (14.8 bits) 0.8 ***** ** * *** 0.6 ****** ** ***** 0.4 ********* ****** 0.2 ********* ****** 0.0 ---------------- Multilevel GCGCCCCCTGGCGGCC consensus CT AT GACT G sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr19:40634430-40634930 + 65 1.79e-09 CAAGCCGGCT GCGCCCCCTAGTGGCC GATGCTCGTA chr6:107114161-107114661 + 48 3.57e-09 AGGGAGCGCT GCGCCCCCTGGCGGCG GGGCCCATCC chr1:235104085-235104585 - 70 8.74e-09 GAGCGCGCTG GCGCCCTCTGGCGGCG ATCCTAGGGT chr1:225474842-225475342 - 46 1.90e-08 CGGGTGCGCA GCGCCCTCTGCCGGCC GACGGGCGTC chr18:48446553-48447053 + 30 2.72e-08 CTGTCTGTGG GTGCCCTCTGGTGGCC TGTCGGCTGG chr15:66497617-66498117 + 46 6.12e-08 GGCGAGGAGT GCGCCCCCTTCCGGCG CCCGCCGTAG chr12:52980742-52981242 + 49 8.45e-08 TTGCCTCCCT CTGCCCCCTGGTGGCC TTCTAGGTGC chr13:36999140-36999640 + 65 1.58e-07 GCTGGCCGCA GCGCCCCCGCGTGGCG AGGCGGAGAA chr1:1375033-1375533 + 27 2.14e-07 CCTACGCACA GCGCCCGCTGGCGTCC TCGCGGCCCC chr12:57782453-57782953 - 25 2.46e-07 AACGAGTATG GTGCCACCTGCTGGCC GGAGGAACAC chr5:139517839-139518339 - 58 2.77e-07 GCTGAGAGCA GCGCCCTCTAGCGGAG GCCGGGCCTT chr17:43483578-43484078 - 25 3.23e-07 ACGCCGATCT GCGCCCTCTACAGGCG AGAAAAATCT chr19:33777972-33778472 - 60 3.76e-07 CAGAGCGCTG CTGCCACCTGGCGGCC CCGCCGGGGA chr14:49861970-49862470 - 78 3.76e-07 CTCATCG CTGCCCCCTACCGGCG CATATTCAAA chr8:23287832-23288332 - 16 4.27e-07 CAGAGACGCA GCGCCACCGCGCGGCC TGGGGGAGGT chr17:18625538-18626038 - 33 4.87e-07 TGGAGCTACA GCGCCACCTGCAGGCC AAGGAGTCTT chrX:74550273-74550773 + 58 4.87e-07 CGGTAGCCGT GCGCCCCCTCCTGGCT GTCCTGCTGA chr19:4400471-4400971 + 68 5.54e-07 AGCAGTTGCA GCGCCCCCTGGAGTCG TGGAGGTGAC chr1:200510053-200510553 + 57 6.29e-07 CTGTGAGACA CTGCCATCTAGTGGCC AATGTGAACA chr19:5803915-5804415 - 26 7.20e-07 CGCTCCCACA GCGCTCCCTGGCGGCG CCGGGCTAAC chr5:178279862-178280362 - 71 9.31e-07 CAGGTCAAGC GCGCCCTCTAGTGTTC CCTGGCCGGG chr17:64919256-64919756 - 76 1.05e-06 TGCTCCCGC GCTCCCCCTAGCGGCC GCCGCGCCAC chr10:32346069-32346569 + 66 1.19e-06 TGGCCCTGGA GCGCCACCCAGCGGCC CACGGAGAGG chr6:118800479-118800979 + 8 1.34e-06 ATACTTC CTGCCCCCTAGTGGTG GGAAGCAGCA chr19:36127649-36128149 - 32 1.34e-06 CGGTGCGCTG CCGCCCCCTCGTGGCA GATGGGCGGT chr3:183884690-183885190 + 59 1.34e-06 GCAGTCTAGA GCGCCCCCGCGCGGCT GAGCGGCAGC chr17:74203334-74203834 - 16 1.68e-06 TTCAGCAGCC CTGCCCCCTTGTGGTC GAAGTCAACA chr9:40991916-40992416 - 43 2.13e-06 CTGCTCCCTG GCGCCCTCTCGAGGAG CCCCTGAGGA chr1:25998096-25998596 + 9 2.66e-06 GTGTGATT CCTCCCCCTGGTGGCC TGAAGAGGTG chr3:87298086-87298586 - 12 2.66e-06 GTGTATCATA GTGCCACCTGCTGGTG TAATTAAAGA chr1:228664361-228664861 - 6 2.96e-06 TGGGGTAATG CTGCCCTCTGCCGGAC AATTT chr1:234997177-234997677 - 2 3.27e-06 ATGTCCCGTG GCGCCCTGTGGTGTCC T chr1:228165605-228166105 - 38 3.65e-06 CCGGGCCGCC GCGCCCCGGAGTGGCG CCTCGAAGCA chr1:211133946-211134446 + 74 4.06e-06 TGGGCCGGCG GCGCCCCCTACCGGGC TCGTGCCCCA chr16:667763-668263 - 35 4.48e-06 GCTGTGCGGC GCGCCACCGTGTGGAC GCGCCGGCCA chr10:72364177-72364677 - 73 4.48e-06 CAGGCTTCAA GTGCCACCTGCTGGCA AGAAGGCTCC chr1:23544613-23545113 - 60 6.09e-06 CAGTGCATGA CTCCCCTCTGGCGGCC AGTTGCTGCA chr13:110593455-11059395 - 8 6.09e-06 TTTGCCTGTA GTGCCCTCTACTGTCT CTAGGAT chr19:40284939-40285439 - 20 6.09e-06 ACAGGTGAGT GCGCCAGCGCGTGTCC CCGAACGCCC chr15:66498750-66499250 + 63 6.72e-06 CTCTCCAGTT GTGCCCTCTTGTGGTT AAAGTTAAAT chr10:6088647-6089147 - 85 6.72e-06 . CTGCCCCCTGCCCGCG GGAGGACCGC chr5:173144210-173144710 - 29 7.40e-06 TCTCGGGGCA GCGCCCCCTAGAGACC GGCGAAAATG chr10:101694078-10169457 - 71 8.14e-06 GTCCGCTCGC CCGCCCGCTCCCCGCC CCGAGCCGGC chr2:55014920-55015420 - 16 8.97e-06 ACGGGTGTTG GTGCCATCTAGTGTTG CAGATGGAAG chr9:137578744-137579244 + 56 1.09e-05 CCAGGCTCCC ACGCCCCCTGTCGGCC GGCTGACCGC chr1:227762367-227762867 - 28 1.19e-05 TGTCGCGAGG CTGCCACCCTGTGGCC ACACGTGCAC chr8:13276305-13276805 + 33 1.30e-05 GCCCCGGGAA GCGCCAACTGCAGGCG GCCTCCTGGC chr19:43754376-43754876 + 55 1.30e-05 CGCTAGCCTC GCGCGGGCTCGCGGCC CCCTTACCTA chr19:41262212-41262712 + 12 1.30e-05 CAGCGCCCGG ACGCCCTCCAGTGGCG GCTCCTGAGA chr1:114346429-114346929 - 77 1.30e-05 GCGCGCTG GCGCCCTCTAATGGAC ACTGCCGAAC chr1:23539755-23540255 + 33 1.43e-05 AAGGTGAAGG CTGCCACCTAGAGGTG AACTCTGGCA chr5:134411673-134412173 + 35 1.57e-05 GACGCGCACT GCGCCACCGCCTGCCG GCCAGAGGGG chr1:150010511-150011011 + 85 1.87e-05 GACACCCAGG CCGCCCCCGGGCCTCC chr5:116574634-116575134 - 4 2.04e-05 GGACTTGGCT CCGCCCGGGAGCGGCG GCC chr19:17334562-17335062 + 17 2.22e-05 GACAAAGGCC GCGCCCGCCCGCGCCG GCCTCGGTCC chr5:43064782-43065282 + 52 2.42e-05 AAAACACGGA GTCGCCCCTAGTGGCG AAAGTGCGGA chr5:140725986-140726486 - 31 2.42e-05 GGGCTGGAGA GCGCCCGCGGGTCTCG AACAACCCAG chr5:140711075-140711575 - 69 2.42e-05 GGACTGGAGA GCGCCCGCGGGTCTCG AACAACCCAG chr1:32817110-32817610 - 82 2.86e-05 TTT CCGGCCGCTGCCGGAG GGGTCCAGGC chr1:54715562-54716062 - 85 3.11e-05 . GCGGCTCCTTCCGGCG GCGCGGGTTC chr7:141551093-141551593 + 22 3.38e-05 GAACTGGCCC GCGCGCGCTCGCAGCC CCGCGGCGGA chr5:112160537-112161037 - 8 3.38e-05 CTATGGCGAG ACGCCGCCGTGTGGCC GGAGGGA chr1:224615887-224616387 - 66 4.30e-05 CGGGCGCTTG GTGGCCGCTGCCGCCG CCACTGCAGC chr17:39980637-39981137 + 6 5.03e-05 CTGCT CCGTCATCGTGCGGCC CGACGCTATC chr3:53347431-53347931 + 56 5.03e-05 CACGCTCCGG GCGCCGGGTTCCGGCG TTGTCAGGGT chr12:751090-751590 + 13 5.43e-05 CTGAAGAGAG GCGGCCGCGTCCGGAC GCTCTGATGC chr6:131628048-131628548 - 84 5.86e-05 G GCGCTCTCGTCCGGCT TGCGGGCCGC chr2:208025290-208025790 + 40 5.86e-05 CTGTTTACAA GCGGCTTCTCGCGGTC CCACTCTGAA chr21:44939702-44940202 + 15 6.33e-05 ccgcgaccct gcgcccgcccgagccg cTTCCGGGTA chr8:37849673-37850173 + 15 6.33e-05 AAGGGTTGCA CCCCCGTCTTCCGGCC AGCGCGACGG chr7:135509619-135510119 + 9 6.82e-05 CGAAGCCT CCGCTCTCTCGTAGCC GGTCAGCCCC chr1:226547613-226548113 - 47 7.35e-05 TGAGGACACA GCGCCGTCTGGCGTTA ATAATGGGGC chr17:19507905-19508405 + 72 7.92e-05 CACCACTTTG GTGTgacctcgtggcg caatggtagc chr7:141072415-141072915 - 31 9.16e-05 GAAGCTGCTG CCGCGCTCTCTCGTCC GGCGCGGGTA chr3:51538391-51538891 - 69 1.13e-04 CTCCCGGCCC GCGCGCCCGACCGCAC GGACGGGAAC chr19:58380514-58381014 - 84 1.22e-04 G CCGCGCACTTCCGGTC CTCGCGCTCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:40634430-40634930 1.8e-09 64_[+4]_20 chr6:107114161-107114661 3.6e-09 47_[+4]_37 chr1:235104085-235104585 8.7e-09 69_[-4]_15 chr1:225474842-225475342 1.9e-08 45_[-4]_39 chr18:48446553-48447053 2.7e-08 29_[+4]_55 chr15:66497617-66498117 6.1e-08 45_[+4]_39 chr12:52980742-52981242 8.5e-08 48_[+4]_36 chr13:36999140-36999640 1.6e-07 64_[+4]_20 chr1:1375033-1375533 2.1e-07 26_[+4]_58 chr12:57782453-57782953 2.5e-07 24_[-4]_60 chr5:139517839-139518339 2.8e-07 57_[-4]_27 chr17:43483578-43484078 3.2e-07 24_[-4]_60 chr19:33777972-33778472 3.8e-07 59_[-4]_25 chr14:49861970-49862470 3.8e-07 77_[-4]_7 chr8:23287832-23288332 4.3e-07 15_[-4]_69 chr17:18625538-18626038 4.9e-07 32_[-4]_52 chrX:74550273-74550773 4.9e-07 57_[+4]_27 chr19:4400471-4400971 5.5e-07 67_[+4]_17 chr1:200510053-200510553 6.3e-07 56_[+4]_28 chr19:5803915-5804415 7.2e-07 25_[-4]_59 chr5:178279862-178280362 9.3e-07 70_[-4]_14 chr17:64919256-64919756 1e-06 75_[-4]_9 chr10:32346069-32346569 1.2e-06 65_[+4]_19 chr6:118800479-118800979 1.3e-06 7_[+4]_77 chr19:36127649-36128149 1.3e-06 31_[-4]_53 chr3:183884690-183885190 1.3e-06 58_[+4]_26 chr17:74203334-74203834 1.7e-06 15_[-4]_69 chr9:40991916-40992416 2.1e-06 42_[-4]_42 chr1:25998096-25998596 2.7e-06 8_[+4]_76 chr3:87298086-87298586 2.7e-06 11_[-4]_73 chr1:228664361-228664861 3e-06 5_[-4]_79 chr1:234997177-234997677 3.3e-06 1_[-4]_83 chr1:228165605-228166105 3.7e-06 37_[-4]_47 chr1:211133946-211134446 4.1e-06 73_[+4]_11 chr16:667763-668263 4.5e-06 34_[-4]_50 chr10:72364177-72364677 4.5e-06 72_[-4]_12 chr1:23544613-23545113 6.1e-06 59_[-4]_25 chr13:110593455-11059395 6.1e-06 7_[-4]_77 chr19:40284939-40285439 6.1e-06 19_[-4]_65 chr15:66498750-66499250 6.7e-06 62_[+4]_22 chr10:6088647-6089147 6.7e-06 84_[-4] chr5:173144210-173144710 7.4e-06 28_[-4]_56 chr10:101694078-10169457 8.1e-06 70_[-4]_14 chr2:55014920-55015420 9e-06 15_[-4]_69 chr9:137578744-137579244 1.1e-05 55_[+4]_29 chr1:227762367-227762867 1.2e-05 27_[-4]_57 chr8:13276305-13276805 1.3e-05 32_[+4]_52 chr19:43754376-43754876 1.3e-05 54_[+4]_30 chr19:41262212-41262712 1.3e-05 11_[+4]_73 chr1:114346429-114346929 1.3e-05 76_[-4]_8 chr1:23539755-23540255 1.4e-05 32_[+4]_52 chr5:134411673-134412173 1.6e-05 34_[+4]_50 chr1:150010511-150011011 1.9e-05 84_[+4] chr5:116574634-116575134 2e-05 3_[-4]_81 chr19:17334562-17335062 2.2e-05 16_[+4]_68 chr5:43064782-43065282 2.4e-05 51_[+4]_33 chr5:140725986-140726486 2.4e-05 30_[-4]_54 chr5:140711075-140711575 2.4e-05 68_[-4]_16 chr1:32817110-32817610 2.9e-05 81_[-4]_3 chr1:54715562-54716062 3.1e-05 84_[-4] chr7:141551093-141551593 3.4e-05 21_[+4]_63 chr5:112160537-112161037 3.4e-05 7_[-4]_77 chr1:224615887-224616387 4.3e-05 65_[-4]_19 chr17:39980637-39981137 5e-05 5_[+4]_79 chr3:53347431-53347931 5e-05 55_[+4]_29 chr12:751090-751590 5.4e-05 12_[+4]_72 chr6:131628048-131628548 5.9e-05 83_[-4]_1 chr2:208025290-208025790 5.9e-05 39_[+4]_45 chr21:44939702-44940202 6.3e-05 14_[+4]_70 chr8:37849673-37850173 6.3e-05 14_[+4]_70 chr7:135509619-135510119 6.8e-05 8_[+4]_76 chr1:226547613-226548113 7.3e-05 46_[-4]_38 chr17:19507905-19508405 7.9e-05 71_[+4]_13 chr7:141072415-141072915 9.2e-05 30_[-4]_54 chr3:51538391-51538891 0.00011 68_[-4]_16 chr19:58380514-58381014 0.00012 83_[-4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCGCCCYCTNSYGGCS width=16 seqs=76 chr19:40634430-40634930 ( 65) GCGCCCCCTAGTGGCC 1 chr6:107114161-107114661 ( 48) GCGCCCCCTGGCGGCG 1 chr1:235104085-235104585 ( 70) GCGCCCTCTGGCGGCG 1 chr1:225474842-225475342 ( 46) GCGCCCTCTGCCGGCC 1 chr18:48446553-48447053 ( 30) GTGCCCTCTGGTGGCC 1 chr15:66497617-66498117 ( 46) GCGCCCCCTTCCGGCG 1 chr12:52980742-52981242 ( 49) CTGCCCCCTGGTGGCC 1 chr13:36999140-36999640 ( 65) GCGCCCCCGCGTGGCG 1 chr1:1375033-1375533 ( 27) GCGCCCGCTGGCGTCC 1 chr12:57782453-57782953 ( 25) GTGCCACCTGCTGGCC 1 chr5:139517839-139518339 ( 58) GCGCCCTCTAGCGGAG 1 chr17:43483578-43484078 ( 25) GCGCCCTCTACAGGCG 1 chr19:33777972-33778472 ( 60) CTGCCACCTGGCGGCC 1 chr14:49861970-49862470 ( 78) CTGCCCCCTACCGGCG 1 chr8:23287832-23288332 ( 16) GCGCCACCGCGCGGCC 1 chr17:18625538-18626038 ( 33) GCGCCACCTGCAGGCC 1 chrX:74550273-74550773 ( 58) GCGCCCCCTCCTGGCT 1 chr19:4400471-4400971 ( 68) GCGCCCCCTGGAGTCG 1 chr1:200510053-200510553 ( 57) CTGCCATCTAGTGGCC 1 chr19:5803915-5804415 ( 26) GCGCTCCCTGGCGGCG 1 chr5:178279862-178280362 ( 71) GCGCCCTCTAGTGTTC 1 chr17:64919256-64919756 ( 76) GCTCCCCCTAGCGGCC 1 chr10:32346069-32346569 ( 66) GCGCCACCCAGCGGCC 1 chr6:118800479-118800979 ( 8) CTGCCCCCTAGTGGTG 1 chr19:36127649-36128149 ( 32) CCGCCCCCTCGTGGCA 1 chr3:183884690-183885190 ( 59) GCGCCCCCGCGCGGCT 1 chr17:74203334-74203834 ( 16) CTGCCCCCTTGTGGTC 1 chr9:40991916-40992416 ( 43) GCGCCCTCTCGAGGAG 1 chr1:25998096-25998596 ( 9) CCTCCCCCTGGTGGCC 1 chr3:87298086-87298586 ( 12) GTGCCACCTGCTGGTG 1 chr1:228664361-228664861 ( 6) CTGCCCTCTGCCGGAC 1 chr1:234997177-234997677 ( 2) GCGCCCTGTGGTGTCC 1 chr1:228165605-228166105 ( 38) GCGCCCCGGAGTGGCG 1 chr1:211133946-211134446 ( 74) GCGCCCCCTACCGGGC 1 chr16:667763-668263 ( 35) GCGCCACCGTGTGGAC 1 chr10:72364177-72364677 ( 73) GTGCCACCTGCTGGCA 1 chr1:23544613-23545113 ( 60) CTCCCCTCTGGCGGCC 1 chr13:110593455-11059395 ( 8) GTGCCCTCTACTGTCT 1 chr19:40284939-40285439 ( 20) GCGCCAGCGCGTGTCC 1 chr15:66498750-66499250 ( 63) GTGCCCTCTTGTGGTT 1 chr10:6088647-6089147 ( 85) CTGCCCCCTGCCCGCG 1 chr5:173144210-173144710 ( 29) GCGCCCCCTAGAGACC 1 chr10:101694078-10169457 ( 71) CCGCCCGCTCCCCGCC 1 chr2:55014920-55015420 ( 16) GTGCCATCTAGTGTTG 1 chr9:137578744-137579244 ( 56) ACGCCCCCTGTCGGCC 1 chr1:227762367-227762867 ( 28) CTGCCACCCTGTGGCC 1 chr8:13276305-13276805 ( 33) GCGCCAACTGCAGGCG 1 chr19:43754376-43754876 ( 55) GCGCGGGCTCGCGGCC 1 chr19:41262212-41262712 ( 12) ACGCCCTCCAGTGGCG 1 chr1:114346429-114346929 ( 77) GCGCCCTCTAATGGAC 1 chr1:23539755-23540255 ( 33) CTGCCACCTAGAGGTG 1 chr5:134411673-134412173 ( 35) GCGCCACCGCCTGCCG 1 chr1:150010511-150011011 ( 85) CCGCCCCCGGGCCTCC 1 chr5:116574634-116575134 ( 4) CCGCCCGGGAGCGGCG 1 chr19:17334562-17335062 ( 17) GCGCCCGCCCGCGCCG 1 chr5:43064782-43065282 ( 52) GTCGCCCCTAGTGGCG 1 chr5:140725986-140726486 ( 31) GCGCCCGCGGGTCTCG 1 chr5:140711075-140711575 ( 69) GCGCCCGCGGGTCTCG 1 chr1:32817110-32817610 ( 82) CCGGCCGCTGCCGGAG 1 chr1:54715562-54716062 ( 85) GCGGCTCCTTCCGGCG 1 chr7:141551093-141551593 ( 22) GCGCGCGCTCGCAGCC 1 chr5:112160537-112161037 ( 8) ACGCCGCCGTGTGGCC 1 chr1:224615887-224616387 ( 66) GTGGCCGCTGCCGCCG 1 chr17:39980637-39981137 ( 6) CCGTCATCGTGCGGCC 1 chr3:53347431-53347931 ( 56) GCGCCGGGTTCCGGCG 1 chr12:751090-751590 ( 13) GCGGCCGCGTCCGGAC 1 chr6:131628048-131628548 ( 84) GCGCTCTCGTCCGGCT 1 chr2:208025290-208025790 ( 40) GCGGCTTCTCGCGGTC 1 chr21:44939702-44940202 ( 15) GCGCCCGCCCGAGCCG 1 chr8:37849673-37850173 ( 15) CCCCCGTCTTCCGGCC 1 chr7:135509619-135510119 ( 9) CCGCTCTCTCGTAGCC 1 chr1:226547613-226548113 ( 47) GCGCCGTCTGGCGTTA 1 chr17:19507905-19508405 ( 72) GTGTGACCTCGTGGCG 1 chr7:141072415-141072915 ( 31) CCGCGCTCTCTCGTCC 1 chr3:51538391-51538891 ( 69) GCGCGCCCGACCGCAC 1 chr19:58380514-58381014 ( 84) CCGCGCACTTCCGGTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 10.2866 E= 2.9e-027 -258 13 135 -1289 -1289 146 -1289 23 -1289 -274 182 -316 -1289 176 -174 -316 -1289 174 -174 -258 -8 137 -200 -316 -316 88 -52 36 -1289 184 -233 -1289 -1289 -200 -33 162 16 -24 37 -46 -416 32 126 -316 -117 88 -1289 79 -316 -200 178 -1289 -416 -200 153 -58 -117 151 -432 -84 -258 92 58 -184 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 76 E= 2.9e-027 0.039474 0.289474 0.671053 0.000000 0.000000 0.723684 0.000000 0.276316 0.000000 0.039474 0.934211 0.026316 0.000000 0.894737 0.078947 0.026316 0.000000 0.881579 0.078947 0.039474 0.223684 0.684211 0.065789 0.026316 0.026316 0.486842 0.184211 0.302632 0.000000 0.947368 0.052632 0.000000 0.000000 0.065789 0.210526 0.723684 0.263158 0.223684 0.342105 0.171053 0.013158 0.328947 0.631579 0.026316 0.105263 0.486842 0.000000 0.407895 0.026316 0.065789 0.907895 0.000000 0.013158 0.065789 0.763158 0.157895 0.105263 0.750000 0.013158 0.131579 0.039474 0.500000 0.394737 0.065789 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCGCCCYCTNSYGGCS MEME-4 regular expression -------------------------------------------------------------------------------- [GC][CT]GCC[CA][CT]C[TG][GAC][GC][CT]GGC[CG] -------------------------------------------------------------------------------- Time 1266.32 secs. ******************************************************************************** ******************************************************************************** MOTIF CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 width = 37 sites = 12 llr = 315 E-value = 1.9e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 Description -------------------------------------------------------------------------------- Simplified A 21133:15:33:2:::83:::a8::34:17:112311 pos.-specific C 753:246243:442:::1:8:::aa6:6:288383:2 probability G ::3:65214476:6aa::::a::::1449:::::168 matrix T 2438:1232:::43::27a2::2:::2::2326:43: bits 2.1 * * 1.9 ** * ** ** 1.7 ** * ** ** 1.5 *** * ***** * Relative 1.2 * *** ******* * * * Entropy 1.0 * ** *** ******* ** * * (37.9 bits) 0.8 * ** *********** ******* * 0.6 ** *** ************************ ** 0.4 ** ******************************* ** 0.2 ************************************* 0.0 ------------------------------------- Multilevel CCGTGGCACGGGCGGGATTCGAACCCACGACCTCTGG consensus TTAAC TGCACTT A AGG T C AT sequence C A C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------------- chr17:8139226-8139726 + 23 1.09e-15 TCCCCGCTAA CTCaggcaccgctgggattcgaacccaggatctcctg tttactagac chr19:33176890-33177390 - 7 5.44e-15 GGACGCTCGG TTGAGGCACCGCTGGGATTCGAACCCAGGATCTCCTG TTTACT chr6:27602349-27602849 + 17 7.23e-14 GGCAAAATAG CTgtgtcagaagtgggattcgaacccacgcctccatg cggagaccag chr16:22296968-22297468 - 20 2.53e-13 AAGACAGCAA CCCTGGCAGCGGTGGGATTCGAACCCACGCCCCCGAA GAGACTGGAG chr16:3152704-3153204 - 35 2.53e-13 TTCGGCCTTT CTTTACCCCGGGTGGGACTCGAACCCACAATCCCTGG CTTAGGAGGC chr6:26576935-26577435 - 24 3.08e-13 GTCAAAACTA CCGTCCTCCGAGCCGGATTCGAACCAGCGACCTAAGG ATACCTTGCT chr17:82494479-82494979 + 39 4.09e-13 AAAAGGGAGT CTAtagcagaggatggtttcgatccatcgacctctgg gttatgggcc chr6:27592572-27593072 + 46 5.40e-13 AAAAACAGGC ACCtagcagaggatggtttcgatccatcgacctctgg gttatgggcc chr14:20657252-20657752 + 9 1.00e-12 CATCACGC ACTtccttcgagctggaatcgaaccagcgacctaagg atgtccgcaa chr1:161530916-161531416 - 35 6.62e-12 AGACAAAAAC CCTTGCGTTGGCCGGGAATCGAACCCGGGTCAACTGC TTGGAAGGCA chr17:39154263-39154763 + 25 1.49e-11 CTCCGGAGCA CAgagggggcacccggatttgaaccggggacctcttg atctgcagtc chr1:16545717-16546217 + 19 2.90e-11 AAAAAGACCC TCTtgcattggccgggaattgaacccgggtctcccgc gtgggaggcg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:8139226-8139726 1.1e-15 22_[+5]_41 chr19:33176890-33177390 5.4e-15 6_[-5]_57 chr6:27602349-27602849 7.2e-14 16_[+5]_47 chr16:22296968-22297468 2.5e-13 19_[-5]_44 chr16:3152704-3153204 2.5e-13 34_[-5]_29 chr6:26576935-26577435 3.1e-13 23_[-5]_40 chr17:82494479-82494979 4.1e-13 38_[+5]_25 chr6:27592572-27593072 5.4e-13 45_[+5]_18 chr14:20657252-20657752 1e-12 8_[+5]_55 chr1:161530916-161531416 6.6e-12 34_[-5]_29 chr17:39154263-39154763 1.5e-11 24_[+5]_39 chr1:16545717-16546217 2.9e-11 18_[+5]_45 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG width=37 seqs=12 chr17:8139226-8139726 ( 23) CTCAGGCACCGCTGGGATTCGAACCCAGGATCTCCTG 1 chr19:33176890-33177390 ( 7) TTGAGGCACCGCTGGGATTCGAACCCAGGATCTCCTG 1 chr6:27602349-27602849 ( 17) CTGTGTCAGAAGTGGGATTCGAACCCACGCCTCCATG 1 chr16:22296968-22297468 ( 20) CCCTGGCAGCGGTGGGATTCGAACCCACGCCCCCGAA 1 chr16:3152704-3153204 ( 35) CTTTACCCCGGGTGGGACTCGAACCCACAATCCCTGG 1 chr6:26576935-26577435 ( 24) CCGTCCTCCGAGCCGGATTCGAACCAGCGACCTAAGG 1 chr17:82494479-82494979 ( 39) CTATAGCAGAGGATGGTTTCGATCCATCGACCTCTGG 1 chr6:27592572-27593072 ( 46) ACCTAGCAGAGGATGGTTTCGATCCATCGACCTCTGG 1 chr14:20657252-20657752 ( 9) ACTTCCTTCGAGCTGGAATCGAACCAGCGACCTAAGG 1 chr1:161530916-161531416 ( 35) CCTTGCGTTGGCCGGGAATCGAACCCGGGTCAACTGC 1 chr17:39154263-39154763 ( 25) CAGAGGGGGCACCCGGATTTGAACCGGGGACCTCTTG 1 chr1:16545717-16546217 ( 19) TCTTGCATTGGCCGGGAATTGAACCCGGGTCTCCCGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 37 n= 38400 bayes= 11.3022 E= 1.9e-022 -50 134 -1023 -50 -150 92 -1023 82 -150 -8 34 50 8 -1023 -1023 167 8 -66 114 -1023 -1023 66 92 -150 -150 114 -66 -50 108 -66 -166 8 -1023 66 66 -50 8 34 66 -1023 50 -1023 134 -1023 -1023 66 114 -1023 -50 66 -1023 82 -1023 -66 114 8 -1023 -1023 192 -1023 -1023 -1023 192 -1023 182 -1023 -1023 -50 8 -166 -1023 150 -1023 -1023 -1023 208 -1023 166 -1023 -50 -1023 -1023 192 -1023 208 -1023 -1023 -1023 182 -1023 -1023 -50 -1023 192 -1023 -1023 -1023 192 -1023 -1023 50 114 -166 -1023 82 -1023 66 -50 -1023 114 66 -1023 -150 -1023 180 -1023 150 -66 -1023 -50 -1023 151 -1023 8 -150 151 -1023 -50 -150 34 -1023 130 -50 166 -1023 -1023 8 -8 -166 82 -150 -1023 114 50 -150 -66 151 -1023 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 37 nsites= 12 E= 1.9e-022 0.166667 0.666667 0.000000 0.166667 0.083333 0.500000 0.000000 0.416667 0.083333 0.250000 0.333333 0.333333 0.250000 0.000000 0.000000 0.750000 0.250000 0.166667 0.583333 0.000000 0.000000 0.416667 0.500000 0.083333 0.083333 0.583333 0.166667 0.166667 0.500000 0.166667 0.083333 0.250000 0.000000 0.416667 0.416667 0.166667 0.250000 0.333333 0.416667 0.000000 0.333333 0.000000 0.666667 0.000000 0.000000 0.416667 0.583333 0.000000 0.166667 0.416667 0.000000 0.416667 0.000000 0.166667 0.583333 0.250000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.833333 0.000000 0.000000 0.166667 0.250000 0.083333 0.000000 0.666667 0.000000 0.000000 0.000000 1.000000 0.000000 0.833333 0.000000 0.166667 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.833333 0.000000 0.000000 0.166667 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.333333 0.583333 0.083333 0.000000 0.416667 0.000000 0.416667 0.166667 0.000000 0.583333 0.416667 0.000000 0.083333 0.000000 0.916667 0.000000 0.666667 0.166667 0.000000 0.166667 0.000000 0.750000 0.000000 0.250000 0.083333 0.750000 0.000000 0.166667 0.083333 0.333333 0.000000 0.583333 0.166667 0.833333 0.000000 0.000000 0.250000 0.250000 0.083333 0.416667 0.083333 0.000000 0.583333 0.333333 0.083333 0.166667 0.750000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CYBTGSCWSVRSYGGGATTCGAACCMRSGACCYCHKG MEME-5 regular expression -------------------------------------------------------------------------------- C[CT][GTC][TA][GA][GC]C[AT][CG][GCA][GA][GC][CT][GT]GGA[TA]TCGAACC[CA][AG][CG]GA[CT]C[TC]C[TAC][GT]G -------------------------------------------------------------------------------- Time 1539.43 secs. ******************************************************************************** ******************************************************************************** MOTIF RRTGACTCA MEME-6 width = 9 sites = 38 llr = 392 E-value = 1.5e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 Description -------------------------------------------------------------------------------- Simplified A 46::a:::a pos.-specific C 12:::9:a: probability G 53:a:1::: matrix T ::a:::a:: bits 2.1 * * * * 1.9 *** *** 1.7 ******* 1.5 ******* Relative 1.2 ******* Entropy 1.0 ******* (14.9 bits) 0.8 ******* 0.6 ******** 0.4 ********* 0.2 ********* 0.0 --------- Multilevel GATGACTCA consensus AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- --------- chr7:112422833-112423333 + 46 3.56e-06 CCGGGGGCAG GATGACTCA GCACTTCCTA chr1:77412411-77412911 + 32 3.56e-06 TATAAATGTT GATGACTCA CCCAATAAAT chr7:128523180-128523680 - 40 3.56e-06 GGGAGCTGAT GATGACTCA CAATCCCTGC chr1:234700197-234700697 + 1 3.56e-06 . GATGACTCA GAGGCATTAT chr1:228861086-228861586 + 87 3.56e-06 AAAAGAAATA GATGACTCA ACCTC chr7:100247220-100247720 - 56 3.56e-06 TCTTCTCAGA GATGACTCA GCTACTCAGC chr15:70271377-70271877 - 73 3.56e-06 TACTGAGCAG GATGACTCA GACCTTCATC chr5:91314204-91314704 + 42 3.56e-06 GCCAGAGCAG GATGACTCA GCAGCCGGAG chr12:2198154-2198654 + 72 3.56e-06 CCGGCATGAG GATGACTCA CCGTTTAACA chr4:53011921-53012421 + 81 6.74e-06 GCCGTGTTAT AATGACTCA CCCCTTGACA chr5:174371533-174372033 - 61 6.74e-06 GCAACGACCA AATGACTCA TTCTCTAAAG chr10:104331421-10433192 - 9 6.74e-06 GCAATTATCA AATGACTCA CTTCCAGG chr5:116766457-116766957 + 69 6.74e-06 AGATAGAAAC AATGACTCA GCCAGTATTA chr11:86592844-86593344 + 68 6.74e-06 CTGCCAGGAA AATGACTCA TTTCTGTATG chr1:68384298-68384798 + 9 1.07e-05 ACTTGTGT GGTGACTCA TATGTTTGAA chr10:18607480-18607980 + 6 1.07e-05 ctgct ggtgactca gatgcagatc chr5:142223565-142224065 + 55 1.07e-05 gggtgccaat ggtgactca tgcctgtaat chr19:11344360-11344860 - 71 1.07e-05 GCCAAGCTGT GGTGACTCA GCTGAGCTGG chr1:223726621-223727121 + 60 1.07e-05 GATGGCCCAG GGTGACTCA TCAGCTACCC chr19:47289313-47289813 - 39 1.07e-05 AGCCAGACAC GGTGACTCA TGCATGTAAT chr5:177546330-177546830 - 11 1.43e-05 AGTGGCTCAG AGTGACTCA TAGCATGTTG chr1:232704735-232705235 + 47 1.43e-05 TCAGCTGCTA AGTGACTCA GCACTGCATC chr18:48998056-48998556 + 34 1.43e-05 AGACATCCGT AGTGACTCA GGGCCCTGGA chr7:95549679-95550179 - 19 1.43e-05 TCTTGGAGCT AGTGACTCA CTCCCTGCTC chr5:76838792-76839292 + 73 1.43e-05 CAACAATTAG AGTGACTCA GACCAACCTT chr1:225508475-225508975 + 36 1.82e-05 TCTAATCTGG GCTGACTCA CTGATGCTGT chr1:225746707-225747207 - 89 1.82e-05 AGG GCTGACTCA GACAGCAGTT chr17:73474227-73474727 + 44 1.82e-05 TCTGTGCAGG GCTGACTCA CAACTGGCCA chr1:46522108-46522608 + 9 2.54e-05 TTtctagc actgactca ctgtggacta chr8:16825905-16826405 - 87 2.54e-05 GGAGT ACTGACTCA TCTATTTGAA chr4:158805594-158806094 - 55 2.54e-05 AGCAGCTTGG ACTGACTCA CTCCATCTGT chr1:156130149-156130649 - 38 2.54e-05 CCACCCTTCC CATGACTCA GGGCTCAGGA chr10:5861247-5861747 + 22 2.54e-05 TCCAGGGATG CATGACTCA GTGGCCTTGA chr6:111591370-111591870 - 49 2.54e-05 TGACACTGGC CATGACTCA GACAAATCAG chr1:7299228-7299728 + 82 2.54e-05 CCTGCTGCTG CATGACTCA GACTCGGAGA chr5:132389703-132390203 + 84 3.29e-05 TCCACCTGCA GATGAGTCA AAACAGTC chr10:87586164-87586664 - 25 4.01e-05 GGGAAGGTCT TATGACTCA TGGCTACATT chr1:235917404-235917904 - 36 4.32e-05 GCATCAAATG AATGAGTCA ATGTGGGCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:112422833-112423333 3.6e-06 45_[+6]_46 chr1:77412411-77412911 3.6e-06 31_[+6]_60 chr7:128523180-128523680 3.6e-06 39_[-6]_52 chr1:234700197-234700697 3.6e-06 [+6]_91 chr1:228861086-228861586 3.6e-06 86_[+6]_5 chr7:100247220-100247720 3.6e-06 55_[-6]_36 chr15:70271377-70271877 3.6e-06 72_[-6]_19 chr5:91314204-91314704 3.6e-06 41_[+6]_50 chr12:2198154-2198654 3.6e-06 71_[+6]_20 chr4:53011921-53012421 6.7e-06 80_[+6]_11 chr5:174371533-174372033 6.7e-06 60_[-6]_31 chr10:104331421-10433192 6.7e-06 8_[-6]_83 chr5:116766457-116766957 6.7e-06 68_[+6]_23 chr11:86592844-86593344 6.7e-06 67_[+6]_24 chr1:68384298-68384798 1.1e-05 8_[+6]_83 chr10:18607480-18607980 1.1e-05 5_[+6]_86 chr5:142223565-142224065 1.1e-05 54_[+6]_37 chr19:11344360-11344860 1.1e-05 70_[-6]_21 chr1:223726621-223727121 1.1e-05 59_[+6]_32 chr19:47289313-47289813 1.1e-05 38_[-6]_53 chr5:177546330-177546830 1.4e-05 10_[-6]_81 chr1:232704735-232705235 1.4e-05 46_[+6]_45 chr18:48998056-48998556 1.4e-05 33_[+6]_58 chr7:95549679-95550179 1.4e-05 18_[-6]_73 chr5:76838792-76839292 1.4e-05 72_[+6]_19 chr1:225508475-225508975 1.8e-05 35_[+6]_56 chr1:225746707-225747207 1.8e-05 88_[-6]_3 chr17:73474227-73474727 1.8e-05 43_[+6]_48 chr1:46522108-46522608 2.5e-05 8_[+6]_83 chr8:16825905-16826405 2.5e-05 86_[-6]_5 chr4:158805594-158806094 2.5e-05 54_[-6]_37 chr1:156130149-156130649 2.5e-05 37_[-6]_54 chr10:5861247-5861747 2.5e-05 21_[+6]_70 chr6:111591370-111591870 2.5e-05 48_[-6]_43 chr1:7299228-7299728 2.5e-05 81_[+6]_10 chr5:132389703-132390203 3.3e-05 83_[+6]_8 chr10:87586164-87586664 4e-05 24_[-6]_67 chr1:235917404-235917904 4.3e-05 35_[-6]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RRTGACTCA width=9 seqs=38 chr7:112422833-112423333 ( 46) GATGACTCA 1 chr1:77412411-77412911 ( 32) GATGACTCA 1 chr7:128523180-128523680 ( 40) GATGACTCA 1 chr1:234700197-234700697 ( 1) GATGACTCA 1 chr1:228861086-228861586 ( 87) GATGACTCA 1 chr7:100247220-100247720 ( 56) GATGACTCA 1 chr15:70271377-70271877 ( 73) GATGACTCA 1 chr5:91314204-91314704 ( 42) GATGACTCA 1 chr12:2198154-2198654 ( 72) GATGACTCA 1 chr4:53011921-53012421 ( 81) AATGACTCA 1 chr5:174371533-174372033 ( 61) AATGACTCA 1 chr10:104331421-10433192 ( 9) AATGACTCA 1 chr5:116766457-116766957 ( 69) AATGACTCA 1 chr11:86592844-86593344 ( 68) AATGACTCA 1 chr1:68384298-68384798 ( 9) GGTGACTCA 1 chr10:18607480-18607980 ( 6) GGTGACTCA 1 chr5:142223565-142224065 ( 55) GGTGACTCA 1 chr19:11344360-11344860 ( 71) GGTGACTCA 1 chr1:223726621-223727121 ( 60) GGTGACTCA 1 chr19:47289313-47289813 ( 39) GGTGACTCA 1 chr5:177546330-177546830 ( 11) AGTGACTCA 1 chr1:232704735-232705235 ( 47) AGTGACTCA 1 chr18:48998056-48998556 ( 34) AGTGACTCA 1 chr7:95549679-95550179 ( 19) AGTGACTCA 1 chr5:76838792-76839292 ( 73) AGTGACTCA 1 chr1:225508475-225508975 ( 36) GCTGACTCA 1 chr1:225746707-225747207 ( 89) GCTGACTCA 1 chr17:73474227-73474727 ( 44) GCTGACTCA 1 chr1:46522108-46522608 ( 9) ACTGACTCA 1 chr8:16825905-16826405 ( 87) ACTGACTCA 1 chr4:158805594-158806094 ( 55) ACTGACTCA 1 chr1:156130149-156130649 ( 38) CATGACTCA 1 chr10:5861247-5861747 ( 22) CATGACTCA 1 chr6:111591370-111591870 ( 49) CATGACTCA 1 chr1:7299228-7299728 ( 82) CATGACTCA 1 chr5:132389703-132390203 ( 84) GATGAGTCA 1 chr10:87586164-87586664 ( 25) TATGACTCA 1 chr1:235917404-235917904 ( 36) AATGAGTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 9 n= 55200 bayes= 11.9447 E= 1.5e-004 64 -133 92 -316 123 -74 13 -1189 -1189 -1189 -1189 208 -1189 -1189 192 -1189 208 -1189 -1189 -1189 -1189 184 -232 -1189 -1189 -1189 -1189 208 -1189 192 -1189 -1189 208 -1189 -1189 -1189 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 9 nsites= 38 E= 1.5e-004 0.368421 0.105263 0.500000 0.026316 0.552632 0.157895 0.289474 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.947368 0.052632 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRTGACTCA MEME-6 regular expression -------------------------------------------------------------------------------- [GA][AG]TGACTCA -------------------------------------------------------------------------------- Time 1816.21 secs. ******************************************************************************** ******************************************************************************** MOTIF CCGSNSCSYKBCBSCBSCGSSG MEME-7 width = 22 sites = 70 llr = 713 E-value = 2.3e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 Description -------------------------------------------------------------------------------- Simplified A ::::211:::::111:::1:1: pos.-specific C 7a16448532383373692453 probability G 3:832514133245144:6646 matrix T ::2:3:11554:21:31:1::: bits 2.1 1.9 1.7 * * 1.5 * * Relative 1.2 * * Entropy 1.0 *** * (14.7 bits) 0.8 *** * * * * * * 0.6 **** ** * * ** * * 0.4 **** ******* ******** 0.2 **** ******* ********* 0.0 ---------------------- Multilevel CCGCCGCCTTTCGGCGCCGGCG consensus G GTC GCGC CC TG CCGC sequence A G C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr1:227735098-227735598 - 15 3.88e-09 CGAGGCTGGT CCTCACCGTTTCCGCTCCGGCG GAAGTGAGGA chr1:226939515-226940015 + 14 1.14e-08 GCGGCCTTGC CCGCCGCGTTTCCCCTCCTCGG AGTGCTTTTT chr17:3004102-3004602 + 14 2.04e-08 CAGCTCTCTC CCGCTCCGTTTCCCCTCCGGAC TCTGGCAGGG chr6:107114161-107114661 + 78 5.82e-08 CCATCCCTCT CCGCTCCCGGCCGCCGCCGCCG C chr15:72231097-72231597 - 45 1.72e-07 GGGCAACCTG CCCGCGCGTTCCGCCGCCGCCG CCGCGCTTCC chr1:1375033-1375533 - 76 2.30e-07 AAA CCGTCGCCTTTCGGGCCCGGCG GGGCCTGAGC chr6:143450468-143450968 - 34 2.65e-07 GGTCCCGGGC CCGCCGCGTTCCGCTGCCCGCG CTCCTCCTCT chr19:33080883-33081383 - 73 3.99e-07 CGGGCC CCGCCCCCTCGCTACGGCGGCC TTGGCAGGCC chr10:93702411-93702911 - 73 5.20e-07 CCCTTT CCGGGCCGTTTCTCCCGCTGCC CTTGTTTCCC chr16:67872808-67873308 + 7 6.72e-07 CCCAGC CCGGAACCTTTCTTCTCCGGCC CTGGCAGGTT chr4:82374296-82374796 - 28 8.64e-07 CAGTGCGCGC GCGGTCCGCTGCGGCGCCTGGC GCTCCGCGGG chr5:134411673-134412173 + 12 9.77e-07 ACCGGATAGC CCGCCGCCTTCCCGACGCGCAC TGCGCCACCG chr7:141551093-141551593 - 41 1.10e-06 GAAACCGCTG CCGCCGCCCTCGGGTTCCGCCG CGGGGCTGCG chr4:4541838-4542338 + 67 1.10e-06 AAGGTTCCGG CCTGCGCCCTGCTACCGCGGCG GGAGGAAAAA chr17:18087620-18088120 + 3 1.40e-06 GT CCGCAGCCTGGCCGGCCCAGCG GGCGGAACCG chr19:43754376-43754876 + 19 1.40e-06 GCGGGGCCTG CCGGAGCGCCCCGCCCGCCGCC GGTGCGCTAG chr1:212791596-212792096 - 59 1.57e-06 AGAGCCGGAG CCGGAACGTTTCAGCTGCAGCG TCCTGAGTTT chr1:235104085-235104585 - 34 1.57e-06 TAGGGTGCGT CCGCGCCGTGCCTACCCCCCGG CCTCCGGGAG chr22:41446598-41447098 + 77 1.77e-06 GTGATGCGTC CCTCCGCCCTGCAGGGGCGGGG CC chr19:40284939-40285439 + 55 1.77e-06 TCACCGGCAG CCGCCCAGCCTCTCCGGCGGGG CTCTACCCCC chr10:17201428-17201928 + 46 1.77e-06 GCTAGGCCTG CCGGTCCGTCGCTCCTCCTCCC TCCATCGCGC chr3:53347431-53347931 - 34 1.98e-06 AACCCGGCGC CCGGAGCGTGCGCGCGGCGGAC CAGAATGGCT chr1:206612236-206612736 - 14 2.21e-06 TGGTTTCCAG CCGGGCCCTTTTCGCGGCCGGG CCCCAGCATG chr22:21982582-21983082 + 57 2.21e-06 GGTGTGCCAG CGTCTGCCCTCCGGCTCCGGCG GGTCGGCGTT chr15:66497617-66498117 + 66 2.47e-06 CCGGCGCCCG CCGTAGCCTGGCCACTCCGCGG GGGACGAGCT chr19:41310105-41310605 - 69 2.76e-06 GACACCGCAA CCGCACCCACCCGCCGCCTGCG CGTGACCAAG chr13:40770985-40771485 + 49 3.08e-06 CTGGCGCCTT CCTCCCCCTTTGCGCTCCGGTG GGCTACAGGG chr15:75368373-75368873 + 47 3.08e-06 AAGGCCCCTG GCGCTACCGTTCCGCTCCACGG CAGGAAACCA chr10:32346069-32346569 - 25 3.08e-06 ACTGCGGCCT GCGCGCCGCTGCCCGGGCCGGG AGCGCAGGTT chr6:157323293-157323793 - 64 3.43e-06 GGAGGCGGTA GCGGAACCTTTCTCCTCCGCCT GGTTCTCGCT chr19:17334562-17335062 + 55 4.24e-06 GCTCGCCCGA GCGCTGCTTCTCGTCCCCGCCC GAGCCGAACC chr1:27321856-27322356 - 43 4.70e-06 GAGATGGGGT CCGCCCCGCTTGGCCTTCCCCC GGGAATCCGA chr19:44212431-44212931 - 55 5.76e-06 CCGCCCTCGG CCTCTCGGCCTCCGCCGCGGCC GCGACCTCTC chr15:73992119-73992619 + 10 6.37e-06 TTCACCCGC GCGGCCACCCGCGGCGGCGCGG GCGCAGGAAG chr12:109477284-10947778 - 76 6.37e-06 GTT CCGCAGAGCTTCTTCGCCCGGG AAGGAAAACT chr16:66406446-66406946 + 29 7.77e-06 TCAGCCAGGG CCGGTGTCTGCGAGCTCCGCGG CCGGGCATCC chr14:90396755-90397255 + 2 7.77e-06 C GCGAGGCGGCTCCGCCGCGGCG GAGGGATACG chr3:149752298-149752798 + 13 7.77e-06 CGCCCGTGTC CCGGCGCCTAGAGGCTCCGGCG TCGCAGCGTC chr7:102572357-102572857 - 47 8.56e-06 GCCGATCCTT GCGCGGGTTTGCCCCGCCGGAG TAATCCGGAA chr19:43596268-43596768 - 78 8.56e-06 C GCTGCGCCTGTCAGCCGCTGGC TACAGCGCCG chr19:45078991-45079491 + 12 8.56e-06 AACCCAGGCT CCGCGGCTTGCGGCCTGCCCGG GCCTCTGCAG chr21:43789223-43789723 + 43 8.56e-06 GGCTGCAGTT GCGCGGCTCGGCCACTGCGCGG CGGTGGCGTG chr12:103956950-10395745 - 70 9.42e-06 TCCCACTTT CCTGTCCGGTGCGGCCCCGGGT CCCTGTATTT chr2:208025290-208025790 - 76 9.42e-06 CCG GCTCTGGCTGCCCGGGCCGCCG GCGGAAGCAT chr11:57741103-57741603 + 18 9.42e-06 CACCATCCCA GCGTCCCCTGTCCCCTCCACCC GAAGCGATGG chr12:62260008-62260508 + 36 9.42e-06 GACCATGGCC GCGCACCCAGTGCGCCCCCGGG GCCTCCTCTT chr17:32341942-32342442 + 35 1.04e-05 CTCCGCCAAA CCGCTCCCCTGCTCCCGTGCAG CCGTCGGTAT chr15:64387528-64388028 - 23 1.04e-05 CACGCGGGTT CCGCCAGCTTGCACCGCCCCGC AAGGTCGCAC chr13:36999140-36999640 + 16 1.14e-05 CGGAAGCGCG CCCGCGCGACCCGGCCCCGCCG CCAGAGAGGT chr15:65517496-65517996 - 32 1.14e-05 CCAGCAGACA GCGGCGCCCTTCTTGGCCCGGC TGCGCCTTCG chr17:50707682-50708182 + 66 1.37e-05 ATTTTCCGTT CCGACCCGGGGCTCCGGCGCCC GGGCTGGCTG chr11:62653127-62653627 + 65 1.50e-05 TACATTAGTT CCGCACCCTGTCGGAGTCCCAG AGCATAATCC chr21:44939702-44940202 + 34 1.50e-05 cgagccgcTT CCGGGTACTTCCGGCGGCCGCG GGGCTCCCGG chr12:38316449-38316949 + 75 1.64e-05 AAACAGCGAC CCGCTGTTTTCCGGATCCGCGC TCTC chr9:105244178-105244678 + 15 1.80e-05 GCCCGGCGCC GCGCAGCCTCTGACACGCGCGG AAGGGCCCGG chr16:667763-668263 + 12 1.96e-05 CCAGGACCCT GCGCTGTCCGCCGTGGCCGGCG CGTCCACACG chr1:244652957-244653457 - 19 2.14e-05 AGCGTACAGC CCGGCCCGCGGCAGCCGGGGCG GAAGCATCGG chr16:66873123-66873623 + 20 2.14e-05 GGCCGCAAAT GCGCGCCGCTTGAGCCTCGGAG GTTCGGAGTC chr5:37378972-37379472 + 64 2.14e-05 GGAAGGCGCC GCTCTTGGCTTCGGCGGCGCCG CTGTAGCTTG chr19:58380514-58381014 - 59 2.54e-05 TCCGGTCCTC GCGCTCCGGGTCCGGACCGGCC ACACAGCACT chr10:101694078-10169457 + 49 2.54e-05 CCGCCCTTTC Ccgggacgcggggccggctcgg ggcggggagc chr17:64919256-64919756 - 51 2.77e-05 AGCGGCCGCC GCGCCACCTCGCCCCGTCCCAG GCTCGTAGGC chr16:690192-690692 + 5 3.27e-05 GAAG CCGCTGTCTTTCCCGTCCCTCG CCGGAAGTGG chr1:228165605-228166105 + 55 4.90e-05 CCGGGGCGCG GCGGCCCGGTCTGGCGCTGGCG GCTGCGCGCG chr1:225474842-225475342 - 67 6.18e-05 ATGCTCGGCA GCGCGCCCCGTCCAACGCGGGT GCGCAGCGCC chr7:141072415-141072915 + 56 8.34e-05 GCAGCAGCTT CCTCCGGCGCCCGCACCCGGGC AATGCGATTT chr19:36127649-36128149 + 50 9.65e-05 GGGGGCGGCA GCGCACCGTTCAGACGCTGCGC CCCTGGTGCA chr17:18780985-18781485 + 47 1.47e-04 TCAGTTCCGA CCCGGACCCGTACGCTGCTGCG CTGACGTGGC chr19:1383558-1384058 - 11 1.57e-04 GCGCTTTCGG CCTCCGTGGTCGTGTTGCGCCG TGCACCCCCA chr17:28902851-28903351 + 47 1.57e-04 GGGGCGTGTG CGCGTGCGGGTGCGCGCCGGCC CTGCGAGCGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:227735098-227735598 3.9e-09 14_[-7]_64 chr1:226939515-226940015 1.1e-08 13_[+7]_65 chr17:3004102-3004602 2e-08 13_[+7]_65 chr6:107114161-107114661 5.8e-08 77_[+7]_1 chr15:72231097-72231597 1.7e-07 44_[-7]_34 chr1:1375033-1375533 2.3e-07 75_[-7]_3 chr6:143450468-143450968 2.6e-07 33_[-7]_45 chr19:33080883-33081383 4e-07 72_[-7]_6 chr10:93702411-93702911 5.2e-07 72_[-7]_6 chr16:67872808-67873308 6.7e-07 6_[+7]_72 chr4:82374296-82374796 8.6e-07 27_[-7]_51 chr5:134411673-134412173 9.8e-07 11_[+7]_67 chr7:141551093-141551593 1.1e-06 40_[-7]_38 chr4:4541838-4542338 1.1e-06 66_[+7]_12 chr17:18087620-18088120 1.4e-06 2_[+7]_76 chr19:43754376-43754876 1.4e-06 18_[+7]_60 chr1:212791596-212792096 1.6e-06 58_[-7]_20 chr1:235104085-235104585 1.6e-06 33_[-7]_45 chr22:41446598-41447098 1.8e-06 76_[+7]_2 chr19:40284939-40285439 1.8e-06 54_[+7]_24 chr10:17201428-17201928 1.8e-06 45_[+7]_33 chr3:53347431-53347931 2e-06 33_[-7]_45 chr1:206612236-206612736 2.2e-06 13_[-7]_65 chr22:21982582-21983082 2.2e-06 56_[+7]_22 chr15:66497617-66498117 2.5e-06 65_[+7]_13 chr19:41310105-41310605 2.8e-06 68_[-7]_10 chr13:40770985-40771485 3.1e-06 48_[+7]_30 chr15:75368373-75368873 3.1e-06 46_[+7]_32 chr10:32346069-32346569 3.1e-06 24_[-7]_54 chr6:157323293-157323793 3.4e-06 63_[-7]_15 chr19:17334562-17335062 4.2e-06 54_[+7]_24 chr1:27321856-27322356 4.7e-06 42_[-7]_36 chr19:44212431-44212931 5.8e-06 54_[-7]_24 chr15:73992119-73992619 6.4e-06 9_[+7]_69 chr12:109477284-10947778 6.4e-06 75_[-7]_3 chr16:66406446-66406946 7.8e-06 28_[+7]_50 chr14:90396755-90397255 7.8e-06 1_[+7]_77 chr3:149752298-149752798 7.8e-06 12_[+7]_66 chr7:102572357-102572857 8.6e-06 46_[-7]_32 chr19:43596268-43596768 8.6e-06 77_[-7]_1 chr19:45078991-45079491 8.6e-06 11_[+7]_67 chr21:43789223-43789723 8.6e-06 42_[+7]_36 chr12:103956950-10395745 9.4e-06 69_[-7]_9 chr2:208025290-208025790 9.4e-06 75_[-7]_3 chr11:57741103-57741603 9.4e-06 17_[+7]_61 chr12:62260008-62260508 9.4e-06 35_[+7]_43 chr17:32341942-32342442 1e-05 34_[+7]_44 chr15:64387528-64388028 1e-05 22_[-7]_56 chr13:36999140-36999640 1.1e-05 15_[+7]_63 chr15:65517496-65517996 1.1e-05 31_[-7]_47 chr17:50707682-50708182 1.4e-05 65_[+7]_13 chr11:62653127-62653627 1.5e-05 64_[+7]_14 chr21:44939702-44940202 1.5e-05 33_[+7]_45 chr12:38316449-38316949 1.6e-05 74_[+7]_4 chr9:105244178-105244678 1.8e-05 14_[+7]_64 chr16:667763-668263 2e-05 11_[+7]_67 chr1:244652957-244653457 2.1e-05 18_[-7]_60 chr16:66873123-66873623 2.1e-05 19_[+7]_59 chr5:37378972-37379472 2.1e-05 63_[+7]_15 chr19:58380514-58381014 2.5e-05 58_[-7]_20 chr10:101694078-10169457 2.5e-05 48_[+7]_30 chr17:64919256-64919756 2.8e-05 50_[-7]_28 chr16:690192-690692 3.3e-05 4_[+7]_74 chr1:228165605-228166105 4.9e-05 54_[+7]_24 chr1:225474842-225475342 6.2e-05 66_[-7]_12 chr7:141072415-141072915 8.3e-05 55_[+7]_23 chr19:36127649-36128149 9.7e-05 49_[+7]_29 chr17:18780985-18781485 0.00015 46_[+7]_32 chr19:1383558-1384058 0.00016 10_[-7]_68 chr17:28902851-28903351 0.00016 46_[+7]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCGSNSCSYKBCBSCBSCGSSG width=22 seqs=70 chr1:227735098-227735598 ( 15) CCTCACCGTTTCCGCTCCGGCG 1 chr1:226939515-226940015 ( 14) CCGCCGCGTTTCCCCTCCTCGG 1 chr17:3004102-3004602 ( 14) CCGCTCCGTTTCCCCTCCGGAC 1 chr6:107114161-107114661 ( 78) CCGCTCCCGGCCGCCGCCGCCG 1 chr15:72231097-72231597 ( 45) CCCGCGCGTTCCGCCGCCGCCG 1 chr1:1375033-1375533 ( 76) CCGTCGCCTTTCGGGCCCGGCG 1 chr6:143450468-143450968 ( 34) CCGCCGCGTTCCGCTGCCCGCG 1 chr19:33080883-33081383 ( 73) CCGCCCCCTCGCTACGGCGGCC 1 chr10:93702411-93702911 ( 73) CCGGGCCGTTTCTCCCGCTGCC 1 chr16:67872808-67873308 ( 7) CCGGAACCTTTCTTCTCCGGCC 1 chr4:82374296-82374796 ( 28) GCGGTCCGCTGCGGCGCCTGGC 1 chr5:134411673-134412173 ( 12) CCGCCGCCTTCCCGACGCGCAC 1 chr7:141551093-141551593 ( 41) CCGCCGCCCTCGGGTTCCGCCG 1 chr4:4541838-4542338 ( 67) CCTGCGCCCTGCTACCGCGGCG 1 chr17:18087620-18088120 ( 3) CCGCAGCCTGGCCGGCCCAGCG 1 chr19:43754376-43754876 ( 19) CCGGAGCGCCCCGCCCGCCGCC 1 chr1:212791596-212792096 ( 59) CCGGAACGTTTCAGCTGCAGCG 1 chr1:235104085-235104585 ( 34) CCGCGCCGTGCCTACCCCCCGG 1 chr22:41446598-41447098 ( 77) CCTCCGCCCTGCAGGGGCGGGG 1 chr19:40284939-40285439 ( 55) CCGCCCAGCCTCTCCGGCGGGG 1 chr10:17201428-17201928 ( 46) CCGGTCCGTCGCTCCTCCTCCC 1 chr3:53347431-53347931 ( 34) CCGGAGCGTGCGCGCGGCGGAC 1 chr1:206612236-206612736 ( 14) CCGGGCCCTTTTCGCGGCCGGG 1 chr22:21982582-21983082 ( 57) CGTCTGCCCTCCGGCTCCGGCG 1 chr15:66497617-66498117 ( 66) CCGTAGCCTGGCCACTCCGCGG 1 chr19:41310105-41310605 ( 69) CCGCACCCACCCGCCGCCTGCG 1 chr13:40770985-40771485 ( 49) CCTCCCCCTTTGCGCTCCGGTG 1 chr15:75368373-75368873 ( 47) GCGCTACCGTTCCGCTCCACGG 1 chr10:32346069-32346569 ( 25) GCGCGCCGCTGCCCGGGCCGGG 1 chr6:157323293-157323793 ( 64) GCGGAACCTTTCTCCTCCGCCT 1 chr19:17334562-17335062 ( 55) GCGCTGCTTCTCGTCCCCGCCC 1 chr1:27321856-27322356 ( 43) CCGCCCCGCTTGGCCTTCCCCC 1 chr19:44212431-44212931 ( 55) CCTCTCGGCCTCCGCCGCGGCC 1 chr15:73992119-73992619 ( 10) GCGGCCACCCGCGGCGGCGCGG 1 chr12:109477284-10947778 ( 76) CCGCAGAGCTTCTTCGCCCGGG 1 chr16:66406446-66406946 ( 29) CCGGTGTCTGCGAGCTCCGCGG 1 chr14:90396755-90397255 ( 2) GCGAGGCGGCTCCGCCGCGGCG 1 chr3:149752298-149752798 ( 13) CCGGCGCCTAGAGGCTCCGGCG 1 chr7:102572357-102572857 ( 47) GCGCGGGTTTGCCCCGCCGGAG 1 chr19:43596268-43596768 ( 78) GCTGCGCCTGTCAGCCGCTGGC 1 chr19:45078991-45079491 ( 12) CCGCGGCTTGCGGCCTGCCCGG 1 chr21:43789223-43789723 ( 43) GCGCGGCTCGGCCACTGCGCGG 1 chr12:103956950-10395745 ( 70) CCTGTCCGGTGCGGCCCCGGGT 1 chr2:208025290-208025790 ( 76) GCTCTGGCTGCCCGGGCCGCCG 1 chr11:57741103-57741603 ( 18) GCGTCCCCTGTCCCCTCCACCC 1 chr12:62260008-62260508 ( 36) GCGCACCCAGTGCGCCCCCGGG 1 chr17:32341942-32342442 ( 35) CCGCTCCCCTGCTCCCGTGCAG 1 chr15:64387528-64388028 ( 23) CCGCCAGCTTGCACCGCCCCGC 1 chr13:36999140-36999640 ( 16) CCCGCGCGACCCGGCCCCGCCG 1 chr15:65517496-65517996 ( 32) GCGGCGCCCTTCTTGGCCCGGC 1 chr17:50707682-50708182 ( 66) CCGACCCGGGGCTCCGGCGCCC 1 chr11:62653127-62653627 ( 65) CCGCACCCTGTCGGAGTCCCAG 1 chr21:44939702-44940202 ( 34) CCGGGTACTTCCGGCGGCCGCG 1 chr12:38316449-38316949 ( 75) CCGCTGTTTTCCGGATCCGCGC 1 chr9:105244178-105244678 ( 15) GCGCAGCCTCTGACACGCGCGG 1 chr16:667763-668263 ( 12) GCGCTGTCCGCCGTGGCCGGCG 1 chr1:244652957-244653457 ( 19) CCGGCCCGCGGCAGCCGGGGCG 1 chr16:66873123-66873623 ( 20) GCGCGCCGCTTGAGCCTCGGAG 1 chr5:37378972-37379472 ( 64) GCTCTTGGCTTCGGCGGCGCCG 1 chr19:58380514-58381014 ( 59) GCGCTCCGGGTCCGGACCGGCC 1 chr10:101694078-10169457 ( 49) CCGGGACGCGGGGCCGGCTCGG 1 chr17:64919256-64919756 ( 51) GCGCCACCTCGCCCCGTCCCAG 1 chr16:690192-690692 ( 5) CCGCTGTCTTTCCCGTCCCTCG 1 chr1:228165605-228166105 ( 55) GCGGCCCGGTCTGGCGCTGGCG 1 chr1:225474842-225475342 ( 67) GCGCGCCCCGTCCAACGCGGGT 1 chr7:141072415-141072915 ( 56) CCTCCGGCGCCCGCACCCGGGC 1 chr19:36127649-36128149 ( 50) GCGCACCGTTCAGACGCTGCGC 1 chr17:18780985-18781485 ( 47) CCCGGACCCGTACGCTGCTGCG 1 chr19:1383558-1384058 ( 11) CCTCCGTGGTCGTGTTGCGCCG 1 chr17:28902851-28903351 ( 47) CGCGTGCGGGTGCGCGCCGGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 10.7876 E= 2.3e-004 -1277 135 32 -1277 -1277 188 -321 -1277 -1277 -221 155 -46 -305 115 38 -246 -24 44 -51 12 -105 60 79 -305 -205 157 -162 -172 -1277 92 70 -172 -246 25 -89 108 -404 -51 18 108 -1277 18 4 86 -246 152 -62 -305 -105 38 44 -35 -124 38 88 -172 -146 149 -104 -246 -404 11 55 41 -1277 108 55 -205 -1277 184 -420 -246 -205 -30 122 -105 -1277 70 108 -404 -105 96 44 -404 -1277 25 128 -246 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 70 E= 2.3e-004 0.000000 0.671429 0.328571 0.000000 0.000000 0.971429 0.028571 0.000000 0.000000 0.057143 0.771429 0.171429 0.028571 0.585714 0.342857 0.042857 0.200000 0.357143 0.185714 0.257143 0.114286 0.400000 0.457143 0.028571 0.057143 0.785714 0.085714 0.071429 0.000000 0.500000 0.428571 0.071429 0.042857 0.314286 0.142857 0.500000 0.014286 0.185714 0.300000 0.500000 0.000000 0.300000 0.271429 0.428571 0.042857 0.757143 0.171429 0.028571 0.114286 0.342857 0.357143 0.185714 0.100000 0.342857 0.485714 0.071429 0.085714 0.742857 0.128571 0.042857 0.014286 0.285714 0.385714 0.314286 0.000000 0.557143 0.385714 0.057143 0.000000 0.942857 0.014286 0.042857 0.057143 0.214286 0.614286 0.114286 0.000000 0.428571 0.557143 0.014286 0.114286 0.514286 0.357143 0.014286 0.000000 0.314286 0.642857 0.042857 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGSNSCSYKBCBSCBSCGSSG MEME-7 regular expression -------------------------------------------------------------------------------- [CG]CG[CG][CTA][GC]C[CG][TC][TG][TCG]C[GC][GC]C[GTC][CG]C[GC][GC][CG][GC] -------------------------------------------------------------------------------- Time 2090.16 secs. ******************************************************************************** ******************************************************************************** MOTIF TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 width = 31 sites = 5 llr = 155 E-value = 2.5e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 Description -------------------------------------------------------------------------------- Simplified A ::2:2:4:a:2:88::8:::4::2:::8:2: pos.-specific C ::68:868:22:2::a2a::6:86aaa::4: probability G :a:2:::::668::a::::a::2:::::a42 matrix T a:2:82:2:2:2:2::::a::a:2:::2::8 bits 2.1 * * * * 1.9 ** * ** *** * *** * 1.7 ** * ** *** * *** * 1.5 ** * * *** *** * ***** Relative 1.2 ** *** ** ********* ** ***** * Entropy 1.0 ** ****** ************ ***** * (44.7 bits) 0.8 ** ****** ************ ***** * 0.6 ***************************** * 0.4 ******************************* 0.2 ******************************* 0.0 ------------------------------- Multilevel TGCCTCCCAGGGAAGCACTGCTCCCCCAGCT consensus AGATAT CATCT C A GA T GG sequence T TC T A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr17:15828724-15829224 + 54 7.65e-19 ACAGGGCCAG TGCCTCCCAGGGAAGCACTGCTCCCCCAGCT GCAGGAAAGA chr17:20646677-20647177 + 33 7.65e-19 ACAGGGCCAG TGCCTCCCAGGGAAGCACTGCTCCCCCAGCT GCAGGAAAGA chr17:20226750-20227250 + 52 1.74e-16 GCAGGGCCAG TGCCTCCCAGGGAAGCACTGCTCTCCCAGGG AAGCACTGCT chr5:95861477-95861977 + 49 2.03e-13 CATGTTTTAG TGACTTACACAGAAGCCCTGATGCCCCTGAT AAAACTGATG chr5:49599400-49599900 - 12 1.01e-12 ACAGGAGCTT TGTGACATATCTCTGCACTGATCACCCAGGT GATTCAACTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:15828724-15829224 7.7e-19 53_[+8]_16 chr17:20646677-20647177 7.7e-19 32_[+8]_37 chr17:20226750-20227250 1.7e-16 51_[+8]_18 chr5:95861477-95861977 2e-13 48_[+8]_21 chr5:49599400-49599900 1e-12 11_[-8]_58 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT width=31 seqs=5 chr17:15828724-15829224 ( 54) TGCCTCCCAGGGAAGCACTGCTCCCCCAGCT 1 chr17:20646677-20647177 ( 33) TGCCTCCCAGGGAAGCACTGCTCCCCCAGCT 1 chr17:20226750-20227250 ( 52) TGCCTCCCAGGGAAGCACTGCTCTCCCAGGG 1 chr5:95861477-95861977 ( 49) TGACTTACACAGAAGCCCTGATGCCCCTGAT 1 chr5:49599400-49599900 ( 12) TGTGACATATCTCTGCACTGATCACCCAGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 13.2876 E= 2.5e-001 -897 -897 -897 208 -897 -897 192 -897 -24 118 -897 -24 -897 160 -40 -897 -24 -897 -897 176 -897 160 -897 -24 76 118 -897 -897 -897 160 -897 -24 208 -897 -897 -897 -897 -40 118 -24 -24 -40 118 -897 -897 -897 160 -24 176 -40 -897 -897 176 -897 -897 -24 -897 -897 192 -897 -897 192 -897 -897 176 -40 -897 -897 -897 192 -897 -897 -897 -897 -897 208 -897 -897 192 -897 76 118 -897 -897 -897 -897 -897 208 -897 160 -40 -897 -24 118 -897 -24 -897 192 -897 -897 -897 192 -897 -897 -897 192 -897 -897 176 -897 -897 -24 -897 -897 192 -897 -24 60 60 -897 -897 -897 -40 176 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 5 E= 2.5e-001 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.200000 0.600000 0.000000 0.200000 0.000000 0.800000 0.200000 0.000000 0.200000 0.000000 0.000000 0.800000 0.000000 0.800000 0.000000 0.200000 0.400000 0.600000 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 1.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.600000 0.200000 0.200000 0.200000 0.600000 0.000000 0.000000 0.000000 0.800000 0.200000 0.800000 0.200000 0.000000 0.000000 0.800000 0.000000 0.000000 0.200000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.800000 0.200000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.400000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.800000 0.200000 0.000000 0.200000 0.600000 0.000000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.200000 0.000000 0.000000 1.000000 0.000000 0.200000 0.400000 0.400000 0.000000 0.000000 0.000000 0.200000 0.800000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTCMCAGGGAAGCACTGMTCCCCCAGVT MEME-8 regular expression -------------------------------------------------------------------------------- TG[CAT][CG][TA][CT][CA][CT]A[GCT][GAC][GT][AC][AT]GC[AC]CTG[CA]T[CG][CAT]CCC[AT]G[CGA][TG] -------------------------------------------------------------------------------- Time 2352.22 secs. ******************************************************************************** ******************************************************************************** MOTIF CCGGAAGTG MEME-9 width = 9 sites = 36 llr = 362 E-value = 3.8e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 Description -------------------------------------------------------------------------------- Simplified A :3::a92:1 pos.-specific C a8:::1:3: probability G ::aa::8:9 matrix T :::::::7: bits 2.1 * 1.9 * *** 1.7 * **** 1.5 * **** * Relative 1.2 ********* Entropy 1.0 ********* (14.5 bits) 0.8 ********* 0.6 ********* 0.4 ********* 0.2 ********* 0.0 --------- Multilevel CCGGAAGTG consensus A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- --------- chr1:44213157-44213657 + 62 4.45e-06 ACAACACCGA CCGGAAGTG TTTCTGTCGG chr1:37989855-37990355 + 29 4.45e-06 TCCGCGAGTG CCGGAAGTG CCCCGGGACT chr15:89893817-89894317 - 1 4.45e-06 AGCGCACCAA CCGGAAGTG chr16:2603064-2603564 + 40 4.45e-06 TTCACTCCCT CCGGAAGTG GGACCAGCCG chr7:128343662-128344162 + 39 4.45e-06 CCGAGAGATT CCGGAAGTG CTCGTTGCCC chr3:131502770-131503270 - 25 4.45e-06 GTAAAACGCA CCGGAAGTG GGTCCGGCGG chr16:690192-690692 + 27 4.45e-06 CCGTCCCTCG CCGGAAGTG GTCCTCTTCT chr6:28080694-28081194 + 40 4.45e-06 AGTCCTTCCA CCGGAAGTG TCCGATCGGA chr8:37849673-37850173 - 78 4.45e-06 GAGGCACAGA CCGGAAGTG GCGCGCAGCC chr16:67872808-67873308 + 62 4.45e-06 CTCGTGGGTG CCGGAAGTG GAGGCGGTTG chr6:28136636-28137136 + 1 4.45e-06 . CCGGAAGTG GCTAGAGGTC chr1:9943157-9943657 - 47 4.45e-06 TTCCAGGGGG CCGGAAGTG CGTGCGTCCA chr13:40770985-40771485 - 29 9.43e-06 AGGCGCCAGG CCGGAAGCG GAAGAGAGGG chr5:40835068-40835568 - 1 1.34e-05 CCGCGCCCCG CAGGAAGTG chr17:43483578-43484078 - 86 1.34e-05 ATCAAA CAGGAAGTG CTTAAGGAAG chr15:59885879-59886379 - 52 1.34e-05 TAACATCCCA CAGGAAGTG GTGTTTGTAC chr19:55216344-55216844 + 92 1.34e-05 TTGAAAGATC CAGGAAGTG chr1:84604285-84604785 - 30 1.34e-05 TACCCAACCC CAGGAAGTG CTATCATTAG chr5:271130-271630 - 66 1.34e-05 CGACCTGGGA CAGGAAGTG ATGGAGCACG chr19:36666592-36667092 + 38 2.14e-05 GAGGCTCCTA CCGGAAGTA GCTGTGGACA chr17:18780985-18781485 + 81 2.14e-05 GACGTGGCTC CCGGAAGTA GGGCTGGCGT chr1:173714639-173715139 - 12 2.14e-05 CGGTGCGGCT CCGGAAGTA GTCGTGCCCT chr3:183884690-183885190 - 11 2.14e-05 TGCCTTCGCC CCGGAAGTA GTTGCGCAGC chr12:109052296-10905279 - 21 2.14e-05 CCCAGGGGGA CCGGAAGTA GCTGCCCCCG chr2:3574932-3575432 - 65 2.58e-05 TAGAGAGTCC CAGGAAGCG GCTCTGGGGA chr19:35612542-35613042 + 65 2.58e-05 GGAGCTAGCG CAGGAAGCG CGGGAACTGG chrX:119943554-119944054 + 33 2.58e-05 TCGTCACCGA CAGGAAGCG ATGTGTGCAT chr6:143450468-143450968 - 67 3.03e-05 TAGACTACCC CCGGAAACG GGGTCCCGGG chr10:47553294-47553794 + 25 3.03e-05 TTGGACACCG CCGGAAACG GAAATTCACC chr13:52194239-52194739 - 17 3.03e-05 ACAAGCCAGA CCGGAAACG GAGGAGAGCG chr19:49580453-49580953 + 45 3.03e-05 CTTTCTCTCT CCGGAAACG TGAGTAGCTA chr5:111092026-111092526 + 86 3.03e-05 AGGGCAGTCT CCGGAAACG CGATTC chr1:183471778-183472278 - 37 3.03e-05 CTCTTCCCCA CCGGAAACG CCGCCCCTTC chr19:58519663-58520163 - 19 3.03e-05 CATAAAAATA CCGGAAACG TGCTTCGGCC chrX:78103807-78104307 + 35 4.68e-05 TCGCGGCGTG CCGGACGTG ACAAACGGAA chr17:42773135-42773635 + 74 4.68e-05 TGCCTTCTGC CCGGACGTG CGGAAGCGAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:44213157-44213657 4.4e-06 61_[+9]_30 chr1:37989855-37990355 4.4e-06 28_[+9]_63 chr15:89893817-89894317 4.4e-06 [-9]_91 chr16:2603064-2603564 4.4e-06 39_[+9]_52 chr7:128343662-128344162 4.4e-06 38_[+9]_53 chr3:131502770-131503270 4.4e-06 24_[-9]_67 chr16:690192-690692 4.4e-06 26_[+9]_65 chr6:28080694-28081194 4.4e-06 39_[+9]_52 chr8:37849673-37850173 4.4e-06 77_[-9]_14 chr16:67872808-67873308 4.4e-06 61_[+9]_30 chr6:28136636-28137136 4.4e-06 [+9]_91 chr1:9943157-9943657 4.4e-06 46_[-9]_45 chr13:40770985-40771485 9.4e-06 28_[-9]_63 chr5:40835068-40835568 1.3e-05 [-9]_91 chr17:43483578-43484078 1.3e-05 85_[-9]_6 chr15:59885879-59886379 1.3e-05 51_[-9]_40 chr19:55216344-55216844 1.3e-05 91_[+9] chr1:84604285-84604785 1.3e-05 29_[-9]_62 chr5:271130-271630 1.3e-05 65_[-9]_26 chr19:36666592-36667092 2.1e-05 37_[+9]_54 chr17:18780985-18781485 2.1e-05 80_[+9]_11 chr1:173714639-173715139 2.1e-05 11_[-9]_80 chr3:183884690-183885190 2.1e-05 10_[-9]_81 chr12:109052296-10905279 2.1e-05 20_[-9]_71 chr2:3574932-3575432 2.6e-05 64_[-9]_27 chr19:35612542-35613042 2.6e-05 64_[+9]_27 chrX:119943554-119944054 2.6e-05 32_[+9]_59 chr6:143450468-143450968 3e-05 66_[-9]_25 chr10:47553294-47553794 3e-05 24_[+9]_67 chr13:52194239-52194739 3e-05 16_[-9]_75 chr19:49580453-49580953 3e-05 44_[+9]_47 chr5:111092026-111092526 3e-05 85_[+9]_6 chr1:183471778-183472278 3e-05 36_[-9]_55 chr19:58519663-58520163 3e-05 18_[-9]_73 chrX:78103807-78104307 4.7e-05 34_[+9]_57 chr17:42773135-42773635 4.7e-05 73_[+9]_18 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCGGAAGTG width=9 seqs=36 chr1:44213157-44213657 ( 62) CCGGAAGTG 1 chr1:37989855-37990355 ( 29) CCGGAAGTG 1 chr15:89893817-89894317 ( 1) CCGGAAGTG 1 chr16:2603064-2603564 ( 40) CCGGAAGTG 1 chr7:128343662-128344162 ( 39) CCGGAAGTG 1 chr3:131502770-131503270 ( 25) CCGGAAGTG 1 chr16:690192-690692 ( 27) CCGGAAGTG 1 chr6:28080694-28081194 ( 40) CCGGAAGTG 1 chr8:37849673-37850173 ( 78) CCGGAAGTG 1 chr16:67872808-67873308 ( 62) CCGGAAGTG 1 chr6:28136636-28137136 ( 1) CCGGAAGTG 1 chr1:9943157-9943657 ( 47) CCGGAAGTG 1 chr13:40770985-40771485 ( 29) CCGGAAGCG 1 chr5:40835068-40835568 ( 1) CAGGAAGTG 1 chr17:43483578-43484078 ( 86) CAGGAAGTG 1 chr15:59885879-59886379 ( 52) CAGGAAGTG 1 chr19:55216344-55216844 ( 92) CAGGAAGTG 1 chr1:84604285-84604785 ( 30) CAGGAAGTG 1 chr5:271130-271630 ( 66) CAGGAAGTG 1 chr19:36666592-36667092 ( 38) CCGGAAGTA 1 chr17:18780985-18781485 ( 81) CCGGAAGTA 1 chr1:173714639-173715139 ( 12) CCGGAAGTA 1 chr3:183884690-183885190 ( 11) CCGGAAGTA 1 chr12:109052296-10905279 ( 21) CCGGAAGTA 1 chr2:3574932-3575432 ( 65) CAGGAAGCG 1 chr19:35612542-35613042 ( 65) CAGGAAGCG 1 chrX:119943554-119944054 ( 33) CAGGAAGCG 1 chr6:143450468-143450968 ( 67) CCGGAAACG 1 chr10:47553294-47553794 ( 25) CCGGAAACG 1 chr13:52194239-52194739 ( 17) CCGGAAACG 1 chr19:49580453-49580953 ( 45) CCGGAAACG 1 chr5:111092026-111092526 ( 86) CCGGAAACG 1 chr1:183471778-183472278 ( 37) CCGGAAACG 1 chr19:58519663-58520163 ( 19) CCGGAAACG 1 chrX:78103807-78104307 ( 35) CCGGACGTG 1 chr17:42773135-42773635 ( 74) CCGGACGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 9 n= 55200 bayes= 11.4299 E= 3.8e+001 -1181 192 -1181 -1181 8 151 -1181 -1181 -1181 -1181 192 -1181 -1181 -1181 192 -1181 208 -1181 -1181 -1181 200 -225 -1181 -1181 -28 -1181 161 -1181 -1181 21 -1181 156 -77 -1181 171 -1181 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 9 nsites= 36 E= 3.8e+001 0.000000 1.000000 0.000000 0.000000 0.250000 0.750000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.944444 0.055556 0.000000 0.000000 0.194444 0.000000 0.805556 0.000000 0.000000 0.305556 0.000000 0.694444 0.138889 0.000000 0.861111 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGTG MEME-9 regular expression -------------------------------------------------------------------------------- C[CA]GGAAG[TC]G -------------------------------------------------------------------------------- Time 2613.16 secs. ******************************************************************************** ******************************************************************************** MOTIF CAGCRCCMCCTRCTGG MEME-10 width = 16 sites = 15 llr = 214 E-value = 3.4e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 Description -------------------------------------------------------------------------------- Simplified A :9:14::3::1312:3 pos.-specific C a::7:996891:7::: probability G ::9:61:1:::51:a7 matrix T :112::1:219118:: bits 2.1 1.9 * * 1.7 * ** * * 1.5 *** ** ** ** Relative 1.2 *** ** *** ** Entropy 1.0 *** *** *** *** (20.5 bits) 0.8 *********** *** 0.6 **************** 0.4 **************** 0.2 **************** 0.0 ---------------- Multilevel CAGCGCCCCCTGCTGG consensus TA AT A A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr17:40560190-40560690 + 53 2.10e-09 TCCTTGGCCA CAGCACCACCTGCTGG AAGCCTCCCT chr15:38354223-38354723 + 83 3.06e-09 TGTGGAGCTT CAGCACCACCTACTGG AT chr17:18625538-18626038 - 83 1.61e-08 TG CAGCACCACCTGCAGG CCAAGGAGTC chr19:38962041-38962541 - 41 2.53e-08 AACGTCTCTC CAGCGCCCTCTACTGA AAAAAACTTA chr10:76103221-76103721 - 67 2.88e-08 AACCTGAGCA CAGAACCCCCTGCTGG AAATGCCTTG chr17:60641722-60642222 + 24 3.71e-08 ggtgtccctt cagcaccctctactga GGAAAAAAGG chr7:102572357-102572857 + 80 7.49e-08 AGGATCGGCT CATCGCCCCCTGTTGG GCTGG chr3:194350134-194350634 + 57 1.16e-07 TTAGCTCCGC CAGTGCCCCCAGctgg gatcagattc chr19:35693677-35694177 - 33 1.51e-07 AGTGGCTCTC CAGCGCCCTCTATTGA CAAAGCCTAA chr19:18349515-18350015 - 2 3.12e-07 CGTGGCGAGA CTGTGCCACCTTCTGG G chr6:155177323-155177823 - 28 3.63e-07 TTAAGCTCTA CTGCACCACCTGGTGG TCTAAAAGCT chr19:40634430-40634930 + 18 3.63e-07 ACAAGCAACG CAGCGCCCCCCGATGG CCACCGCGCG chr20:32270580-32271080 - 22 4.54e-07 GGTGACATCC CAGCGCCCCTTTCAGG AAGAAACAAG chr17:18780985-18781485 + 2 9.96e-07 A CAGTGGTCCCTGCTGG CCCTTGGTGA chr2:27663587-27664087 + 15 1.19e-06 GCAACTTCAC CATCGCCGCCTACAGA CGCCACTGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:40560190-40560690 2.1e-09 52_[+10]_32 chr15:38354223-38354723 3.1e-09 82_[+10]_2 chr17:18625538-18626038 1.6e-08 82_[-10]_2 chr19:38962041-38962541 2.5e-08 40_[-10]_44 chr10:76103221-76103721 2.9e-08 66_[-10]_18 chr17:60641722-60642222 3.7e-08 23_[+10]_61 chr7:102572357-102572857 7.5e-08 79_[+10]_5 chr3:194350134-194350634 1.2e-07 56_[+10]_28 chr19:35693677-35694177 1.5e-07 32_[-10]_52 chr19:18349515-18350015 3.1e-07 1_[-10]_83 chr6:155177323-155177823 3.6e-07 27_[-10]_57 chr19:40634430-40634930 3.6e-07 17_[+10]_67 chr20:32270580-32271080 4.5e-07 21_[-10]_63 chr17:18780985-18781485 1e-06 1_[+10]_83 chr2:27663587-27664087 1.2e-06 14_[+10]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGCRCCMCCTRCTGG width=16 seqs=15 chr17:40560190-40560690 ( 53) CAGCACCACCTGCTGG 1 chr15:38354223-38354723 ( 83) CAGCACCACCTACTGG 1 chr17:18625538-18626038 ( 83) CAGCACCACCTGCAGG 1 chr19:38962041-38962541 ( 41) CAGCGCCCTCTACTGA 1 chr10:76103221-76103721 ( 67) CAGAACCCCCTGCTGG 1 chr17:60641722-60642222 ( 24) CAGCACCCTCTACTGA 1 chr7:102572357-102572857 ( 80) CATCGCCCCCTGTTGG 1 chr3:194350134-194350634 ( 57) CAGTGCCCCCAGCTGG 1 chr19:35693677-35694177 ( 33) CAGCGCCCTCTATTGA 1 chr19:18349515-18350015 ( 2) CTGTGCCACCTTCTGG 1 chr6:155177323-155177823 ( 28) CTGCACCACCTGGTGG 1 chr19:40634430-40634930 ( 18) CAGCGCCCCCCGATGG 1 chr20:32270580-32271080 ( 22) CAGCGCCCCTTTCAGG 1 chr17:18780985-18781485 ( 2) CAGTGGTCCCTGCTGG 1 chr2:27663587-27664087 ( 15) CATCGCCGCCTACAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 11.6559 E= 3.4e+000 -1055 192 -1055 -1055 188 -1055 -1055 -82 -1055 -1055 171 -82 -182 147 -1055 -24 76 -1055 118 -1055 -1055 182 -198 -1055 -1055 182 -1055 -182 50 118 -198 -1055 -1055 160 -1055 -24 -1055 182 -1055 -182 -182 -198 -1055 188 50 -1055 101 -82 -182 147 -198 -82 -24 -1055 -1055 176 -1055 -1055 192 -1055 18 -1055 147 -1055 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 15 E= 3.4e+000 0.000000 1.000000 0.000000 0.000000 0.866667 0.000000 0.000000 0.133333 0.000000 0.000000 0.866667 0.133333 0.066667 0.733333 0.000000 0.200000 0.400000 0.000000 0.600000 0.000000 0.000000 0.933333 0.066667 0.000000 0.000000 0.933333 0.000000 0.066667 0.333333 0.600000 0.066667 0.000000 0.000000 0.800000 0.000000 0.200000 0.000000 0.933333 0.000000 0.066667 0.066667 0.066667 0.000000 0.866667 0.333333 0.000000 0.533333 0.133333 0.066667 0.733333 0.066667 0.133333 0.200000 0.000000 0.000000 0.800000 0.000000 0.000000 1.000000 0.000000 0.266667 0.000000 0.733333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCRCCMCCTRCTGG MEME-10 regular expression -------------------------------------------------------------------------------- CAG[CT][GA]CC[CA][CT]CT[GA]C[TA]G[GA] -------------------------------------------------------------------------------- Time 2870.55 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:154627781-154628281 9.20e-02 100 chr19:39390690-39391190 6.58e-02 100 chr12:44948623-44949123 5.18e-01 100 chr17:39154263-39154763 8.95e-05 24_[+5(1.49e-11)]_39 chr13:30617622-30618122 1.74e-01 100 chr19:29528305-29528805 6.84e-01 100 chr6:149233274-149233774 1.38e-02 44_[+5(5.72e-06)]_19 chr3:149752298-149752798 9.65e-03 12_[+7(7.77e-06)]_66 chr1:9943157-9943657 8.33e-03 46_[-9(4.45e-06)]_45 chr10:17201428-17201928 7.94e-02 45_[+7(1.77e-06)]_33 chr17:2264020-2264520 1.35e-02 27_[-3(6.73e-05)]_11_[+1(1.38e-07)]_\ 34 chr16:2751907-2752407 5.94e-01 100 chr10:94673555-94674055 3.16e-01 100 chr9:137578744-137579244 4.69e-03 55_[+4(1.09e-05)]_29 chr5:14156539-14157039 4.10e-01 100 chr22:41367037-41367537 1.46e-03 34_[+1(2.56e-06)]_50 chr1:223731376-223731876 6.60e-03 54_[+1(3.78e-08)]_30 chr6:27478628-27479128 1.36e-01 36_[+7(9.65e-05)]_42 chr6:107459242-107459742 1.10e-02 100 chr6:41278887-41279387 1.23e-02 31_[+1(4.42e-08)]_53 chr19:47289313-47289813 2.05e-02 38_[-6(1.07e-05)]_15_[+2(2.75e-05)]_\ 24 chr17:19507905-19508405 4.55e-01 71_[+4(7.92e-05)]_13 chr19:37078071-37078571 2.73e-01 100 chr21:35256478-35256978 4.67e-01 82_[-1(6.44e-05)]_2 chr7:100673377-100673877 9.07e-01 100 chr17:28902851-28903351 3.45e-01 100 chr11:86592844-86593344 4.47e-04 48_[-1(1.22e-07)]_3_[+6(6.74e-06)]_\ 24 chr14:70359531-70360031 3.98e-01 100 chr1:23539755-23540255 3.46e-02 32_[+4(1.43e-05)]_52 chr7:135509619-135510119 2.11e-01 8_[+4(6.82e-05)]_76 chr13:113208500-11320900 9.21e-02 19_[+7(9.42e-06)]_59 chr5:271130-271630 7.74e-04 18_[-2(6.39e-07)]_33_[-9(1.34e-05)]_\ 26 chr3:64995977-64996477 5.34e-02 25_[+2(3.16e-05)]_61 chr5:76838792-76839292 8.02e-02 39_[-3(1.90e-05)]_21_[+6(1.43e-05)]_\ 19 chr3:8444313-8444813 3.92e-02 49_[+2(2.73e-06)]_37 chr15:40763151-40763651 1.10e-02 33_[+1(1.22e-07)]_51 chr15:67792453-67792953 3.49e-01 100 chr1:89719612-89720112 6.89e-02 20_[+2(7.68e-06)]_66 chr12:62260008-62260508 9.99e-03 35_[+7(9.42e-06)]_43 chr19:7257118-7257618 2.29e-01 23_[+2(7.11e-05)]_63 chr1:23019103-23019603 8.71e-01 100 chr6:26576935-26577435 1.05e-06 23_[-5(3.08e-13)]_40 chr2:158953840-158954340 8.42e-01 100 chr12:109052296-10905279 1.59e-02 20_[-9(2.14e-05)]_71 chr1:218285000-218285500 1.84e-01 100 chr15:66497617-66498117 1.28e-06 45_[+7(2.45e-08)]_33 chr13:77329164-77329664 7.86e-03 31_[-3(5.41e-06)]_57 chr1:161621403-161621903 8.01e-01 100 chr8:23287832-23288332 1.07e-03 15_[-4(4.27e-07)]_30_[-4(1.71e-05)]_\ 23 chr1:223726621-223727121 3.97e-02 11_[-1(6.72e-05)]_32_[+6(1.07e-05)]_\ 32 chr5:134411673-134412173 3.40e-04 11_[+7(9.77e-07)]_1_[+4(1.57e-05)]_\ 50 chr1:224615887-224616387 3.88e-02 66_[-7(4.18e-05)]_12 chr1:229558645-229559145 5.20e-01 100 chr5:37378972-37379472 6.03e-02 63_[+7(2.14e-05)]_15 chr5:140711075-140711575 4.73e-01 68_[-4(2.42e-05)]_16 chr7:139133463-139133963 7.62e-01 100 chr7:141072415-141072915 1.11e-01 30_[-4(9.16e-05)]_9_[+7(8.34e-05)]_\ 23 chr3:191774480-191774980 2.51e-01 [-6(8.01e-05)]_91 chr12:56192886-56193386 9.99e-02 13_[+2(1.72e-05)]_73 chrX:119943554-119944054 4.52e-02 32_[+9(2.58e-05)]_11_[+2(8.04e-05)]_\ 34 chr21:43789223-43789723 4.47e-03 24_[-10(1.27e-05)]_2_[+7(8.56e-06)]_\ 36 chr19:33176890-33177390 8.68e-08 6_[-5(5.44e-15)]_57 chr15:41402274-41402774 9.25e-01 100 chr16:70778873-70779373 2.93e-01 12_[+8(4.68e-05)]_57 chr17:60641722-60642222 6.87e-05 23_[+10(3.71e-08)]_12_\ [-1(2.18e-06)]_33 chr19:40284939-40285439 2.15e-04 19_[-4(6.09e-06)]_19_[+7(1.77e-06)]_\ 24 chr18:48446553-48447053 2.08e-06 29_[+4(2.72e-08)]_29_[+3(8.38e-06)]_\ 14 chr10:72364177-72364677 1.54e-05 33_[-1(1.29e-06)]_23_[-4(4.48e-06)]_\ 12 chr12:120291514-12029201 3.72e-01 100 chr19:38667027-38667527 1.66e-01 100 chr4:186216656-186217156 8.67e-02 51_[+1(2.61e-07)]_33 chr10:86399840-86400340 1.73e-01 100 chr17:74203334-74203834 2.77e-03 15_[-4(1.68e-06)]_69 chr3:183884690-183885190 7.28e-04 10_[-9(2.14e-05)]_39_[+4(1.34e-06)]_\ 26 chr13:98507161-98507661 1.16e-03 24_[-1(4.42e-08)]_60 chr19:35612542-35613042 1.43e-01 64_[+9(2.58e-05)]_27 chr6:45445728-45446228 1.96e-02 21_[-1(5.78e-06)]_63 chr6:27602349-27602849 3.04e-07 16_[+5(7.23e-14)]_47 chr15:64387528-64388028 2.03e-02 22_[-7(1.04e-05)]_46_[+9(6.83e-05)]_\ 1 chr16:22298264-22298764 9.07e-01 100 chr6:26331218-26331718 5.70e-03 22_[+5(6.57e-05)]_41 chr16:66873123-66873623 3.23e-01 19_[+7(2.14e-05)]_59 chr5:116766457-116766957 2.29e-01 68_[+6(6.74e-06)]_23 chr1:150010511-150011011 5.79e-02 32_[+9(7.23e-05)]_43_[+4(1.87e-05)] chr1:7299228-7299728 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7.56e-04 67_[-1(2.28e-09)]_17 chr1:234997177-234997677 1.12e-04 1_[-4(3.27e-06)]_7_[-1(2.00e-06)]_\ 60 chr11:65961996-65962496 1.76e-02 5_[-2(5.13e-05)]_2_[+2(6.39e-07)]_\ 65 chr17:78558303-78558803 9.52e-01 100 chr10:94069810-94070310 2.55e-01 46_[+1(5.18e-05)]_38 chr15:70741158-70741658 2.08e-01 100 chr5:124061672-124062172 1.71e-01 100 chr17:40108310-40108810 3.80e-04 42_[-2(6.63e-08)]_10_[+3(5.41e-06)]_\ 22 chr6:85498822-85499322 4.39e-03 27_[+1(5.78e-06)]_35_[-9(5.43e-05)]_\ 13 chr6:143450468-143450968 1.12e-03 33_[-7(2.65e-07)]_11_[-9(3.03e-05)]_\ 25 chr1:77412411-77412911 4.82e-03 31_[+6(3.56e-06)]_1_[+2(6.30e-05)]_\ 45 chr12:56636711-56637211 1.41e-03 29_[-1(1.18e-06)]_21_\ [-10(7.17e-05)]_18 chr1:234523521-234524021 7.12e-03 50_[+1(1.04e-07)]_34 chr17:43671068-43671568 1.65e-01 81_[+3(1.52e-05)]_7 chr17:39980637-39981137 1.24e-01 5_[+4(5.03e-05)]_79 chr3:37197613-37198113 1.29e-02 15_[-3(5.23e-08)]_73 chr15:70062307-70062807 4.10e-03 36_[+1(1.18e-06)]_48 chr1:234724153-234724653 1.24e-04 42_[-1(8.01e-07)]_42 chr3:55692915-55693415 9.27e-03 6_[-2(1.72e-05)]_35_[-2(4.80e-05)]_\ 2_[+3(5.23e-08)]_17 chr2:95333888-95334388 4.76e-03 58_[-3(3.55e-06)]_6_[-1(3.57e-05)]_\ 8 chr1:209884518-209885018 2.72e-01 21_[+2(1.47e-05)]_65 chr6:149011880-149012380 3.68e-01 40_[-9(5.83e-05)]_51 chr5:132389703-132390203 2.19e-02 83_[+6(3.29e-05)]_8 chr1:93078913-93079413 4.45e-02 100 chr1:37989855-37990355 1.38e-01 28_[+9(4.45e-06)]_63 chrX:73944048-73944548 2.92e-02 100 chr1:151070353-151070853 2.79e-02 15_[+2(9.16e-07)]_71 chr19:18349515-18350015 4.42e-05 1_[-10(3.12e-07)]_60_[+2(3.68e-07)]_\ 9 chr1:232620479-232620979 4.46e-02 31_[+1(9.83e-07)]_53 chr1:214469215-214469715 2.34e-02 28_[+2(2.16e-07)]_58 chr1:1375033-1375533 7.67e-06 26_[+4(2.14e-07)]_33_[-7(2.30e-07)]_\ 3 chr1:109438736-109439236 1.55e-01 8_[-3(3.55e-06)]_80 chr1:44213157-44213657 1.01e-01 61_[+9(4.45e-06)]_30 chr11:106078021-10607852 1.20e-01 62_[+2(7.68e-06)]_24 chr7:23298894-23299394 9.01e-01 100 chr10:124917810-12491831 3.15e-02 37_[-3(2.23e-06)]_51 chr5:399675-400175 1.59e-01 44_[+2(9.10e-05)]_42 chr5:172437410-172437910 3.38e-03 45_[+1(3.74e-06)]_39 chr17:70661149-70661649 4.92e-02 13_[-2(2.75e-05)]_10_[+3(8.10e-05)]_\ 51 chr15:89383546-89384046 2.49e-04 41_[-1(7.41e-08)]_25_[+1(1.38e-07)]_\ 2 chr15:65610930-65611430 2.71e-02 82_[+10(7.65e-05)]_2 chr2:55014920-55015420 9.14e-05 15_[-4(8.97e-06)]_17_[-3(2.07e-06)]_\ 40 chr4:53011921-53012421 1.44e-02 16_[+2(4.13e-06)]_50_[+6(6.74e-06)]_\ 11 chr6:131628048-131628548 4.14e-02 39_[+10(6.07e-05)]_28_\ [-4(5.86e-05)]_1 chr8:30382234-30382734 1.42e-01 56_[+3(2.12e-05)]_32 chr9:129334002-129334502 1.89e-02 30_[+3(3.55e-06)]_58 chr19:35757455-35757955 7.66e-01 100 chr1:153880943-153881443 4.44e-02 44_[+1(8.92e-07)]_40 chr6:53927177-53927677 3.02e-03 29_[-1(2.18e-06)]_30_[+3(1.65e-06)]_\ 13 chr19:48539554-48540054 5.17e-03 56_[-1(1.06e-08)]_28 chr12:57846932-57847432 2.13e-02 52_[-2(3.30e-07)]_34 chr2:170530187-170530687 7.99e-05 19_[+1(2.97e-06)]_10_[+3(5.41e-06)]_\ 8_[+2(6.70e-05)]_21 chr7:116547259-116547759 3.87e-03 24_[+8(8.53e-06)]_45 chr1:80054126-80054626 4.39e-02 68_[-1(3.42e-07)]_16 chr15:33126616-33127116 6.18e-02 44_[-3(3.31e-05)]_44 chr10:21724680-21725180 2.91e-02 62_[+1(5.87e-07)]_22 chr1:23544613-23545113 5.66e-04 19_[+3(7.79e-06)]_28_[-4(6.09e-06)]_\ 25 chr10:112565447-11256594 5.74e-01 100 chr10:87586164-87586664 5.96e-04 24_[-6(4.01e-05)]_17_[-1(2.03e-07)]_\ 34 chr17:28599396-28599896 1.96e-01 7_[-1(7.30e-05)]_52_[+2(2.18e-05)]_\ 11 chr1:76759959-76760459 5.82e-02 70_[-3(5.41e-06)]_18 chr11:85628101-85628601 1.66e-04 19_[+9(8.94e-05)]_19_[+2(1.05e-06)]_\ 12_[-7(6.67e-05)]_5 chrX:78103807-78104307 3.25e-01 34_[+9(4.68e-05)]_57 chr1:197180308-197180808 1.57e-01 66_[+2(2.82e-07)]_20 chr22:25942957-25943457 3.81e-01 100 chr20:32270580-32271080 5.83e-04 21_[-10(4.54e-07)]_20_\ [+2(2.16e-07)]_29 chr4:82374296-82374796 3.37e-04 27_[-7(8.64e-07)]_5_[-3(2.77e-05)]_\ 34 chr1:229221077-229221577 1.16e-01 45_[-2(1.47e-05)]_41 chr5:124908556-124909056 5.56e-01 100 chr7:113421625-113422125 5.65e-01 100 chr5:124706624-124707124 2.63e-01 54_[-2(1.34e-05)]_32 chr1:212488389-212488889 2.92e-01 7_[-2(1.11e-05)]_79 chr5:66757140-66757640 2.60e-04 26_[+2(9.39e-06)]_34_\ [+10(1.59e-06)]_10 chr16:84138675-84139175 5.18e-02 71_[+3(2.07e-06)]_17 chr5:10601227-10601727 5.47e-03 27_[-1(3.84e-07)]_11_[-1(6.20e-06)]_\ 30 chr7:112422833-112423333 1.71e-03 45_[+6(3.56e-06)]_46 chr16:69073279-69073779 3.79e-02 100 chr6:155177323-155177823 8.19e-05 27_[-10(3.63e-07)]_3_[+2(1.96e-06)]_\ 40 chr6:118800479-118800979 4.58e-04 7_[+4(1.34e-06)]_63_[+3(5.21e-05)]_\ 2 chr5:177546330-177546830 1.14e-02 10_[-6(1.43e-05)]_17_[+3(1.65e-06)]_\ 52 chr13:112102298-11210279 1.94e-01 45_[-2(2.73e-06)]_41 chr5:124661428-124661928 4.73e-01 100 chr6:43630028-43630528 7.66e-01 100 chr4:185095932-185096432 3.14e-02 14_[-2(4.51e-05)]_2_[+3(2.83e-06)]_\ 58 chr12:40224917-40225417 3.08e-01 66_[-3(6.03e-05)]_22 chr12:54039773-54040273 1.30e-02 45_[-3(1.90e-05)]_3_[+2(9.39e-06)]_\ 26 chr5:157511503-157512003 7.08e-01 100 chr15:38354223-38354723 1.29e-06 11_[+2(4.27e-07)]_14_[+3(1.56e-05)]_\ 31_[+10(3.06e-09)]_2 chr8:120859583-120860083 1.96e-02 77_[-2(4.13e-06)]_9 chr4:38620878-38621378 1.82e-01 37_[-2(1.47e-05)]_49 chr12:53501377-53501877 1.04e-03 50_[+2(1.11e-05)]_4_[+1(2.36e-06)]_\ 16 chr10:116891095-11689159 2.06e-02 32_[-2(1.05e-06)]_54 chr17:78974979-78975479 3.66e-01 70_[+2(2.23e-06)]_16 chr3:14125641-14126141 8.87e-02 39_[-2(3.10e-06)]_47 chr22:37330363-37330863 3.03e-02 56_[+3(8.13e-07)]_32 chr6:37171929-37172429 1.04e-01 43_[+3(8.38e-06)]_45 chr1:200510053-200510553 2.86e-04 56_[+4(6.29e-07)]_28 chr1:46522108-46522608 1.42e-02 8_[+6(2.54e-05)]_4_[-2(5.19e-07)]_\ 65 chr1:110338807-110339307 5.81e-02 38_[-3(1.09e-06)]_50 chr1:223819689-223820189 1.28e-01 14_[+2(2.82e-07)]_72 chr16:1271747-1272247 3.45e-02 22_[-1(2.61e-07)]_22_[-1(2.61e-07)]_\ 24 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (10) found. ******************************************************************************** CPU: surya ********************************************************************************