# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 RTGACGTCABNR MEME-1 RTGACGTCABNR 1.8e-169 2.4e-172 -395.15 0.0 115 489 465 593 0.23517 1.0e-174 244 1 GGSSCCKCSGTGACGTCASAGS MEME-2 GGSSCCKCSGTGACGTCASAGS 6.5e-055 8.7e-058 -131.38 0.0 117 479 192 266 0.24426 3.6e-060 239 1 TGACKCA MEME-3 TGACKCA 3.1e-028 4.2e-031 -69.95 0.0 160 494 148 200 0.32389 1.7e-033 246 1 ATGACMTCAYYS MEME-4 ATGACMTCAYYS 7.4e-073 9.9e-076 -172.70 0.0 121 489 264 371 0.24744 4.1e-078 244 1 RSCGGAAGT MEME-5 RSCGGAAGT 2.7e-011 3.6e-014 -30.97 0.0 92 492 96 226 0.18699 1.5e-016 245 1 CTATGRYGTCGSCGAAGRCSCG MEME-7 CTATGRYGTCGSCGAAGRCSCG 2.6e-005 3.4e-008 -17.19 0.0 89 479 15 16 0.18580 1.4e-010 239 2 CGTCAY DREME-1 CGTCAY 4.2e-120 5.6e-123 -281.49 0.0 107 495 347 477 0.21616 2.3e-125 247 2 TGASRTCA DREME-2 TGACATCA 1.2e-084 1.6e-087 -199.87 0.0 91 493 227 327 0.18458 6.4e-090 246 2 RSCGGAA DREME-3 RSCGGAA 5.2e-006 7.0e-009 -18.78 0.0 264 494 159 211 0.53441 2.8e-011 246 2 TGACKCA DREME-4 TGACTCA 3.1e-028 4.2e-031 -69.95 0.0 160 494 148 200 0.32389 1.7e-033 246 2 ACGTMA DREME-7 ACGTMA 1.9e-105 2.6e-108 -247.72 0.0 95 495 284 403 0.19192 1.1e-110 247 3 M0189_1.02 (ID2)_(Mus_musculus)_(DBD_0.98) RCACGTGR 6.9e-003 9.2e-006 -11.60 0.0 61 493 104 496 0.12373 3.7e-008 246 3 M0198_1.02 (SOHLH2)_(Mus_musculus)_(DBD_0.84) NRYVCGTGCN 4.4e0000 5.9e-003 -5.13 0.0 45 491 82 564 0.09165 2.4e-005 245 3 M0211_1.02 (MLXIP)_(Mus_musculus)_(DBD_0.82) BCACGTGK 2.0e-002 2.7e-005 -10.53 0.0 101 493 152 501 0.20487 1.1e-007 246 3 M0212_1.02 (TCFL5)_(Mus_musculus)_(DBD_1.00) NBCDCGHGVN 2.0e0000 2.7e-003 -5.92 0.0 89 491 116 438 0.18126 1.1e-005 245 3 M0300_1.02 (ATF2)_(Mus_musculus)_(DBD_1.00) NRTKACGTMA 1.3e-142 1.7e-145 -333.35 0.0 115 491 441 599 0.23422 6.9e-148 245 3 M0305_1.02 (CREB3L2)_(Mus_musculus)_(DBD_1.00) GCCACGTGD 1.1e-022 1.4e-025 -57.21 0.0 82 492 182 489 0.16667 5.8e-028 245 3 M0413_1.02 (ZBTB1)_(Mus_musculus)_(DBD_0.99) NDTGCGKGDN 4.0e-001 5.3e-004 -7.54 0.0 265 491 357 560 0.53971 2.2e-006 245 3 M0424_1.02 (SNAI3)_(Mus_musculus)_(DBD_0.75) NNTGACAKNN 7.4e-022 9.8e-025 -55.28 0.0 85 491 214 600 0.17312 4.0e-027 245 3 M0432_1.02 (ZFP161)_(Mus_musculus)_(DBD_1.00) NNCGYGCHH 3.2e0000 4.2e-003 -5.46 0.0 132 492 150 414 0.26829 1.7e-005 245 3 M0607_1.02 KDM2B NCGNDNNNN 5.7e-002 7.6e-005 -9.49 0.0 80 492 48 143 0.16260 3.1e-007 245 3 M0608_1.02 MLL NNNRSCGNDN 1.6e-004 2.2e-007 -15.34 0.0 157 491 201 439 0.31976 8.9e-010 245 3 M0610_1.02 TET1 NNYRCGYWN 2.0e-005 2.6e-008 -17.46 0.0 90 492 146 481 0.18293 1.1e-010 245 3 M0714_1.02 (ENSG00000235187)_(Mus_musculus)_(DBD_1.00) NDBCGGAARY 5.8e-004 7.7e-007 -14.08 0.0 233 491 352 593 0.47454 3.1e-009 245 3 M1281_1.02 (NAIF1)_(Xenopus_tropicalis)_(DBD_0.71) NNTACGYHN 1.5e-021 2.0e-024 -54.59 0.0 146 492 256 482 0.29675 8.0e-027 245 3 M1432_1.02 NR2E1 NYTGACCTCD 6.9e-036 9.2e-039 -87.59 0.0 89 491 245 582 0.18126 3.7e-041 245 3 M1458_1.02 (RORB)_(Tetraodon_nigroviridis)_(DBD_1.00) NNTGACCTCN 2.1e-017 2.8e-020 -45.01 0.0 89 491 203 574 0.18126 1.2e-022 245 3 M1545_1.02 GMEB1 NNNRCGTNN 8.2e-107 1.1e-109 -250.89 0.0 90 492 341 555 0.18293 4.5e-112 245 3 M1581_1.02 (CIC)_(Mus_musculus)_(DBD_1.00) NNTGCTGACW 1.1e0000 1.4e-003 -6.56 0.0 273 491 370 572 0.55601 5.8e-006 245 3 M1917_1.02 USF1 GGTCACRTGRB 1.0e-007 1.4e-010 -22.72 0.0 62 490 121 491 0.12653 5.6e-013 244 3 M2065_1.02 ESR2 RGGKCANBSTGACCT 8.2e-003 1.1e-005 -11.42 0.0 150 486 226 539 0.30864 4.5e-008 242 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 2.2e-001 2.9e-004 -8.15 0.0 264 488 369 577 0.54098 1.2e-006 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 6.1e-001 8.1e-004 -7.12 0.0 242 490 346 590 0.49388 3.3e-006 244 3 M2278_1.02 FOS DVTGASTCATB 2.3e-001 3.1e-004 -8.08 0.0 160 490 193 444 0.32653 1.3e-006 244 3 M2289_1.02 JUN DDRATGATGTMAT 1.7e-096 2.2e-099 -227.16 0.0 120 488 379 562 0.24590 9.1e-102 243 3 M2292_1.02 JUND DRTGASTCATS 4.7e-001 6.2e-004 -7.38 0.0 160 490 185 426 0.32653 2.6e-006 244 3 M2387_1.02 SREBF1 RTGGGGTGAB 2.0e-025 2.7e-028 -63.48 0.0 107 491 246 567 0.21792 1.1e-030 245 3 M2388_1.02 SREBF2 RTGGGGTGAY 2.0e-021 2.7e-024 -54.26 0.0 83 491 200 560 0.16904 1.1e-026 245 3 M4451_1.02 ATF3 GGTCACGTGRS 1.9e-067 2.6e-070 -160.23 0.0 88 490 283 540 0.17959 1.1e-072 244 3 M4462_1.02 GABPA VVCCGGAAGTG 3.0e-007 3.9e-010 -21.65 0.0 176 490 276 545 0.35918 1.6e-012 244 3 M4481_1.02 USF2 GGTCACGTGRSSSSV 1.7e-013 2.2e-016 -36.03 0.0 48 486 108 443 0.09877 9.3e-019 242 3 M4511_1.02 RXRA TGACCYYW 2.5e0000 3.3e-003 -5.72 0.0 127 493 198 590 0.25761 1.3e-005 246 3 M4522_1.02 ELK4 CCGGAAGYGS 9.8e-002 1.3e-004 -8.95 0.0 25 491 57 555 0.05092 5.3e-007 245 3 M4526_1.02 SMARCC1 DSRVDGTGASTCABV 1.6e-004 2.1e-007 -15.38 0.0 140 486 199 474 0.28807 8.6e-010 242 3 M4553_1.02 BHLHE40 NGKCACGTGC 1.3e-006 1.8e-009 -20.15 0.0 105 491 175 507 0.21385 7.3e-012 245 3 M4565_1.02 FOSL2 VDGGATGASTCAYH 3.9e-004 5.2e-007 -14.47 0.0 167 487 208 432 0.34292 2.1e-009 243 3 M4619_1.02 FOSL1 BGGTGASTCAK 2.5e-002 3.3e-005 -10.32 0.0 162 490 193 427 0.33061 1.4e-007 244 3 M4623_1.02 JUNB NDRTGASTCATNYHY 4.0e-002 5.4e-005 -9.83 0.0 140 486 179 446 0.28807 2.2e-007 242 3 M4629_1.02 NFE2 VRTGACTCAGCANWWYB 1.6e-002 2.1e-005 -10.76 0.0 214 484 217 375 0.44215 8.8e-008 241 3 M4680_1.02 BACH1 GTCACGTG 2.0e-022 2.7e-025 -56.59 0.0 89 493 202 528 0.18053 1.1e-027 246 3 M4681_1.02 BACH2 TGCTGAGTCA 4.9e-003 6.6e-006 -11.93 0.0 217 491 235 406 0.44196 2.7e-008 245 3 M4930_1.02 (NPAS4)_(Drosophila_melanogaster)_(DBD_0.61) RADTCGTGACT 9.6e-004 1.3e-006 -13.57 0.0 214 490 244 423 0.43673 5.2e-009 244 3 M4971_1.02 (FERD3L)_(Drosophila_melanogaster)_(DBD_0.89) GTVACAGVTG 5.3e0000 7.0e-003 -4.96 0.0 163 491 236 570 0.33198 2.9e-005 245 3 M5234_1.02 (SIM1)_(Drosophila_melanogaster)_(DBD_0.89) GGTCACGTAC 5.3e-017 7.0e-020 -44.10 0.0 57 491 128 448 0.11609 2.9e-022 245 3 M5292_1.02 ATF4 GKATGAYGCAATM 1.8e-060 2.4e-063 -144.19 0.0 96 488 287 544 0.19672 9.9e-066 243 3 M5293_1.02 ATF7 NKATGACGTCATHN 2.3e-139 3.1e-142 -325.85 0.0 119 487 413 536 0.24435 1.3e-144 243 3 M5302_1.02 BATF3 TGATGACGTCATCA 8.3e-091 1.1e-093 -214.04 0.0 119 487 282 373 0.24435 4.5e-096 243 3 M5323_1.02 CREB3 KGRTGACGTCAYNV 5.1e-129 6.8e-132 -302.03 0.0 119 487 407 544 0.24435 2.8e-134 243 3 M5325_1.02 CREB3L1 TGRTGACGTGGCAB 1.7e-023 2.3e-026 -59.02 0.0 107 487 201 437 0.21971 9.6e-029 243 3 M5377_1.02 ELF4 AACCCGGAAGTR 7.9e-001 1.1e-003 -6.86 0.0 177 489 219 472 0.36196 4.3e-006 244 3 M5398_1.02 ERF ACCGGAAGTR 9.3e-004 1.2e-006 -13.60 0.0 241 491 335 545 0.49084 5.1e-009 245 3 M5420_1.02 ETV1 ACCGGAAGTD 8.9e-004 1.2e-006 -13.65 0.0 215 491 311 556 0.43788 4.8e-009 245 3 M5422_1.02 ETV3 ACCGGAAGTR 7.3e-004 9.7e-007 -13.85 0.0 93 491 164 562 0.18941 4.0e-009 245 3 M5425_1.02 ETV6 CCGGAASCGGAAGYR 1.7e0000 2.2e-003 -6.10 0.0 232 486 217 368 0.47737 9.3e-006 242 3 M5493_1.02 GMEB2 KTRCGTAA 8.3e-081 1.1e-083 -191.02 0.0 89 493 307 556 0.18053 4.5e-086 246 3 M5509_1.02 HEY1 GRCACGTGBC 1.5e-001 2.0e-004 -8.52 0.0 43 491 70 434 0.08758 8.1e-007 245 3 M5581_1.02 IRX2 CDTGTCRTGTWN 3.0e-003 4.1e-006 -12.41 0.0 71 489 128 546 0.14519 1.7e-008 244 3 M5582_1.02 IRX5 SWTGTYRTGTWN 2.7e-002 3.7e-005 -10.22 0.0 75 489 131 553 0.15337 1.5e-007 244 3 M5587_1.02 JDP2 ATGASTCAT 1.0e-005 1.3e-008 -18.13 0.0 214 492 222 368 0.43496 5.5e-011 245 3 M5621_1.02 MEIS3 SCTGTCAH 2.3e-003 3.1e-006 -12.68 0.0 109 493 191 597 0.22110 1.3e-008 246 3 M5632_1.02 MLX RTCACGTGAT 2.1e-028 2.8e-031 -70.35 0.0 97 491 186 398 0.19756 1.1e-033 245 3 M5634_1.02 MNT VVCACGTGVH 1.4e0000 1.8e-003 -6.30 0.0 85 491 121 480 0.17312 7.5e-006 245 3 M5689_1.02 NRL DWWNTGCTGAC 7.4e0000 9.9e-003 -4.62 0.0 100 490 160 588 0.20408 4.1e-005 244 3 M5702_1.02 PAX1 DKCABTCAWGCGTGACG 4.0e-013 5.4e-016 -35.16 0.0 116 484 142 301 0.23967 2.2e-018 241 3 M5711_1.02 PAX9 KKCASTCAWGCGTGACS 1.5e-009 2.0e-012 -26.95 0.0 116 484 108 226 0.23967 8.2e-015 241 3 M5753_1.02 PROX1 YAAGACGYCTTA 6.8e-005 9.1e-008 -16.22 0.0 83 489 109 358 0.16973 3.7e-010 244 3 M5889_1.02 TBX21 GGTGTGAHWTCACACC 1.5e-008 2.0e-011 -24.62 0.0 89 485 111 305 0.18351 8.4e-014 242 3 M5932_1.02 TFEC VTCAYGTGAY 1.0e-008 1.4e-011 -25.02 0.0 75 491 151 542 0.15275 5.6e-014 245 3 M5958_1.02 ZBED1 YATGTCGCGAYAG 8.5e-004 1.1e-006 -13.69 0.0 86 488 60 163 0.17623 4.7e-009 243 3 M5998_1.02 (CREB5)_(Mus_musculus)_(DBD_1.00) DRTGACGTCATN 3.8e-141 5.0e-144 -329.96 0.0 119 489 424 555 0.24335 2.1e-146 244 3 M6139_1.02 AHR KCACGCRAH 2.5e-002 3.3e-005 -10.32 0.0 90 492 148 539 0.18293 1.3e-007 245 3 M6151_1.02 ARNT BYRCGTGC 2.7e-010 3.6e-013 -28.64 0.0 89 493 165 501 0.18053 1.5e-015 246 3 M6152_1.02 ATF1 VTGACGTCAV 1.5e-143 2.0e-146 -335.49 0.0 87 491 393 596 0.17719 8.1e-149 245 3 M6155_1.02 ATF6 GBGSTGACGTGG 3.6e-052 4.8e-055 -125.07 0.0 111 489 289 526 0.22699 2.0e-057 244 3 M6162_1.02 ARNTL GRGTCACGTGTYCM 7.5e0000 1.0e-002 -4.61 0.0 45 487 54 334 0.09240 4.1e-005 243 3 M6166_1.02 CDC5L RWTAYRTTAAMWCVC 2.4e-003 3.3e-006 -12.63 0.0 80 486 132 500 0.16461 1.3e-008 242 3 M6172_1.02 CEBPE VAKATTDCGHAA 1.9e-007 2.5e-010 -22.11 0.0 115 489 206 557 0.23517 1.0e-012 244 3 M6180_1.02 CREB1 RTGACGTMA 8.5e-168 1.1e-170 -391.31 0.0 108 492 454 599 0.21951 4.7e-173 245 3 M6181_1.02 CREM CRVTGACGTCA 3.1e-113 4.2e-116 -265.68 0.0 106 490 391 592 0.21633 1.7e-118 244 3 M6186_1.02 DBP BVTTRCATAAB 1.1e-005 1.4e-008 -18.07 0.0 80 490 145 528 0.16327 5.8e-011 244 3 M6197_1.02 E4F1 YGTKACGTC 2.5e-131 3.4e-134 -307.33 0.0 106 492 407 583 0.21545 1.4e-136 245 3 M6207_1.02 ELK1 RCCGGAAGT 7.9e-003 1.0e-005 -11.46 0.0 242 492 356 591 0.49187 4.3e-008 245 3 M6208_1.02 ELK3 VMCHGGAARTSC 6.1e-001 8.1e-004 -7.11 0.0 93 489 149 552 0.19018 3.3e-006 244 3 M6213_1.02 ERG ACCGGAARTSM 8.4e-003 1.1e-005 -11.40 0.0 236 490 315 526 0.48163 4.6e-008 244 3 M6216_1.02 ESRRG TGACCTTGA 2.1e-004 2.9e-007 -15.07 0.0 110 492 186 556 0.22358 1.2e-009 245 3 M6221_1.02 ETS2 VMVGGAAGTKS 6.7e0000 9.0e-003 -4.72 0.0 246 490 347 595 0.50204 3.7e-005 244 3 M6224_1.02 ETV7 KCMHCAGGAAGTRACDY 1.7e-006 2.2e-009 -19.92 0.0 94 484 151 462 0.19421 9.3e-012 241 3 M6226_1.02 FEV CAGGAARTDA 2.9e-003 3.9e-006 -12.47 0.0 111 491 187 569 0.22607 1.6e-008 245 3 M6275_1.02 HIF1A SBSTACGTGCSB 5.9e-002 7.9e-005 -9.45 0.0 87 489 133 494 0.17791 3.2e-007 244 3 M6276_1.02 HINFP DMSNHMGCGGACGTTV 1.4e-003 1.8e-006 -13.22 0.0 179 485 213 420 0.36907 7.5e-009 242 3 M6277_1.02 HLF SKRTTACRYAAYC 1.1e-030 1.4e-033 -75.64 0.0 112 488 247 513 0.22951 5.8e-036 243 3 M6331_1.02 MAFB WGCTGACDS 7.7e-013 1.0e-015 -34.51 0.0 94 492 203 596 0.19106 4.2e-018 245 3 M6332_1.02 MAF KTGCTGAC 3.3e-002 4.4e-005 -10.03 0.0 77 493 141 595 0.15619 1.8e-007 246 3 M6333_1.02 MAFG MATGACT 1.2e-067 1.6e-070 -160.70 0.0 94 494 311 598 0.19028 6.6e-073 246 3 M6345_1.02 MITF VKCACATGWY 1.6e0000 2.1e-003 -6.15 0.0 85 491 136 554 0.17312 8.7e-006 245 3 M6346_1.02 MLXIPL VCACGVSGKKGBCMCRTGC 2.7e0000 3.6e-003 -5.64 0.0 114 482 124 372 0.23651 1.5e-005 240 3 M6352_1.02 MYCN CCACGTGS 6.7e0000 8.9e-003 -4.72 0.0 45 493 73 491 0.09128 3.6e-005 246 3 M6359_1.02 NFE2L1 NATGACD 2.6e-047 3.4e-050 -113.90 0.0 94 494 279 600 0.19028 1.4e-052 246 3 M6360_1.02 NFE2L2 VRTGACTCAGCA 1.8e0000 2.3e-003 -6.06 0.0 177 489 258 573 0.36196 9.6e-006 244 3 M6368_1.02 NFIL3 VKVMVTTACRTAAY 1.3e-033 1.7e-036 -82.37 0.0 89 487 216 493 0.18275 7.0e-039 243 3 M6406_1.02 PAX2 RHKCAGTSAYGMGTGAYW 1.2e-007 1.6e-010 -22.53 0.0 87 483 164 531 0.18012 6.8e-013 241 3 M6419_1.02 PKNOX1 MATCARTCAMBYB 3.2e0000 4.2e-003 -5.46 0.0 44 488 77 529 0.09016 1.7e-005 243 3 M6443_1.02 RARA TGACCTB 3.4e-029 4.6e-032 -72.16 0.0 118 494 281 599 0.23887 1.9e-034 246 3 M6445_1.02 RARB BBBBTGACCTS 1.3e-006 1.7e-009 -20.20 0.0 148 490 254 582 0.30204 6.9e-012 244 3 M6461_1.02 RXRB YSTGACCTSA 1.7e-032 2.2e-035 -79.78 0.0 89 491 243 596 0.18126 9.1e-038 245 3 M6510_1.02 TEF TGTTTATRTAAMTK 1.1e-013 1.5e-016 -36.46 0.0 93 487 193 549 0.19097 6.0e-019 243 3 M6517_1.02 TFE3 RGTCAYGTGV 3.2e0000 4.3e-003 -5.45 0.0 97 491 150 552 0.19756 1.8e-005 245 3 M6518_1.02 TFEB RGTCACGTG 5.6e-025 7.4e-028 -62.47 0.0 96 492 182 412 0.19512 3.0e-030 245 3 M6519_1.02 TGIF1 MWGSTGACACCTSMCA 9.8e-008 1.3e-010 -22.76 0.0 69 485 150 588 0.14227 5.4e-013 242 3 M6521_1.02 THRA STGACCTSAV 1.7e-015 2.3e-018 -40.60 0.0 105 491 226 590 0.21385 9.5e-021 245 3 M6523_1.02 THRB TGACCTSABSTSRSSYC 1.3e-007 1.7e-010 -22.51 0.0 102 484 194 570 0.21074 6.9e-013 241 3 M6536_1.02 XBP1 GACGTGKCMHWW 1.7e-010 2.3e-013 -29.10 0.0 79 489 127 388 0.16155 9.4e-016 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).