******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.12.0 (Release date: Tue Jun 27 16:22:50 2017 -0700) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme-suite.org . This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme-suite.org . ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF580.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr13:45464572-45465072 1.0000 100 chr6:27544050-27544550 1.0000 100 chr6:27505640-27506140 1.0000 100 chr1:167162990-167163490 1.0000 100 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100 chr6:27495576-27496076 1.0000 100 chr10:75379137-75379637 1.0000 100 chr19:44164671-44165171 1.0000 100 chr6:127343088-127343588 1.0000 100 chr16:690202-690702 1.0000 100 chr1:163321558-163322058 1.0000 100 chr11:2400275-2400775 1.0000 100 chr6:31958779-31959279 1.0000 100 chr14:20461431-20461931 1.0000 100 chr1:40257882-40258382 1.0000 100 chr21:46286062-46286562 1.0000 100 chr16:71808709-71809209 1.0000 100 chr14:21511156-21511656 1.0000 100 chr1:1375104-1375604 1.0000 100 chr3:17730375-17730875 1.0000 100 chr6:90587028-90587528 1.0000 100 chr8:37302631-37303131 1.0000 100 chr1:80403305-80403805 1.0000 100 chr11:93783967-93784467 1.0000 100 chr16:84186779-84187279 1.0000 100 chr7:133492160-133492660 1.0000 100 chr5:150449660-150450160 1.0000 100 chr7:151842352-151842852 1.0000 100 chr2:201071700-201072200 1.0000 100 chr3:9952344-9952844 1.0000 100 chr3:15098912-15099412 1.0000 100 chr11:61792430-61792930 1.0000 100 chr7:108569513-108570013 1.0000 100 chr16:2047673-2048173 1.0000 100 chr18:49460605-49461105 1.0000 100 chr7:130440790-130441290 1.0000 100 chr5:173144665-173145165 1.0000 100 chr11:118251992-11825249 1.0000 100 chr1:169367868-169368368 1.0000 100 chr17:59707369-59707869 1.0000 100 chr6:36874590-36875090 1.0000 100 chr12:53501261-53501761 1.0000 100 chr19:35248559-35249059 1.0000 100 chr12:51172704-51173204 1.0000 100 chr16:1420557-1421057 1.0000 100 chr2:24076212-24076712 1.0000 100 chr1:230978766-230979266 1.0000 100 chr5:59303215-59303715 1.0000 100 chr6:82260138-82260638 1.0000 100 chr16:30571838-30572338 1.0000 100 chr12:806374-806874 1.0000 100 chr1:224330205-224330705 1.0000 100 chr3:48439898-48440398 1.0000 100 chr16:2682197-2682697 1.0000 100 chr1:20732198-20732698 1.0000 100 chr19:17932753-17933253 1.0000 100 chr14:44961891-44962391 1.0000 100 chr17:57849799-57850299 1.0000 100 chr1:167936275-167936775 1.0000 100 chr19:12681637-12682137 1.0000 100 chr5:81301369-81301869 1.0000 100 chr1:43389617-43390117 1.0000 100 chr1:100132760-100133260 1.0000 100 chr5:159263006-159263506 1.0000 100 chr12:38316440-38316940 1.0000 100 chr12:6663085-6663585 1.0000 100 chr12:34022154-34022654 1.0000 100 chr19:36666555-36667055 1.0000 100 chr7:5822859-5823359 1.0000 100 chr3:14651489-14651989 1.0000 100 chr19:39435664-39436164 1.0000 100 chr5:149345136-149345636 1.0000 100 chr1:154182976-154183476 1.0000 100 chr14:90383121-90383621 1.0000 100 chr19:43950898-43951398 1.0000 100 chr5:37371026-37371526 1.0000 100 chr1:156740987-156741487 1.0000 100 chr15:55196721-55197221 1.0000 100 chr7:102748618-102749118 1.0000 100 chr19:44259548-44260048 1.0000 100 chr1:150293606-150294106 1.0000 100 chr8:143281438-143281938 1.0000 100 chr12:48105899-48106399 1.0000 100 chr12:49567884-49568384 1.0000 100 chr7:93232066-93232566 1.0000 100 chr19:38849854-38850354 1.0000 100 chr17:42154862-42155362 1.0000 100 chr1:155934240-155934740 1.0000 100 chr16:30650436-30650936 1.0000 100 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF580.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered -oc /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF580.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/meme_out -mod zoops -nmotifs 10 -minw 5 -maxw 50 -bfile /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF580.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background -dna -revcomp -nostatus model: mod= zoops nmotifs= 10 evt= inf object function= E-value of product of p-values width: minw= 5 maxw= 50 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 600 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 60000 N= 600 shuffle= -1 strands: + - sample: seed= 0 ctfrac= -1 maxwords= -1 Letter frequencies in dataset: A 0.232 C 0.269 G 0.269 T 0.232 Background letter frequencies (from /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/ZNF580.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background): A 0.229 C 0.271 G 0.271 T 0.229 ******************************************************************************** ******************************************************************************** MOTIF BRCTTCCGGTYB MEME-1 width = 12 sites = 188 llr = 1783 E-value = 6.7e-153 ******************************************************************************** -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 Description -------------------------------------------------------------------------------- Simplified A 15::::::::11 pos.-specific C 4:8::aa:1133 probability G 231::::a9222 matrix T 212aa::::743 bits 2.1 * 1.9 **** 1.7 ***** 1.5 ****** Relative 1.3 ****** Entropy 1.1 ******* (13.7 bits) 0.9 ******** 0.6 ******** 0.4 ********* 0.2 *********** 0.0 ------------ Multilevel CACTTCCGGTTC consensus TG GCT sequence G G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr5:159263006-159263506 + 46 5.71e-08 TCAAACCACC CACTTCCGGTTT TTCAGCCGGT chr15:65517429-65517929 + 54 1.25e-07 GAGGCTTTAG CACTTCCGGTTC GTTGCGATCC chr16:667901-668401 - 1 1.25e-07 GCCCGCCCCG CACTTCCGGTTC chr19:16197635-16198135 - 71 1.25e-07 AGCTCACCTC CACTTCCGGTTC GGGGAGCCGC chr11:64317420-64317920 - 7 1.25e-07 GCAAGTTCGC CACTTCCGGTTC TCCTGG chr17:50372899-50373399 + 85 1.92e-07 TTCGATCACT CACTTCCGGTCT CGAA chr19:49451588-49452088 + 34 1.92e-07 AACGAAGCCA CACTTCCGGTCT ATCGGTAAAC chr15:90265356-90265856 + 86 1.92e-07 CCGCCCCTTC CACTTCCGGTCT TAC chr3:14651489-14651989 + 62 3.88e-07 CTGTCGAAGA CACTTCCGGTTG CGACGGAGGT chr6:36874590-36875090 + 61 3.88e-07 CGCTGCTGCA CACTTCCGGTCC GTTCAACCCT chr17:59707369-59707869 - 65 3.88e-07 CCGCTCACGT CACTTCCGGTCC GGTCCCTCTG chr16:84186779-84187279 - 74 3.88e-07 CCGCAGGAGG CACTTCCGGTCC AAACCGGAAG chr6:28136607-28137107 - 27 3.88e-07 GACCTCTAGC CACTTCCGGTTG CTAACGGTTC chr14:74881627-74882127 + 65 3.88e-07 CGGCCCGCCC CACTTCCGGTTG TTGTCCGGCC chr16:77190860-77191360 - 65 3.88e-07 TCCCAGAAGA CACTTCCGGTTG CGGAGCTTTA chr15:89893816-89894316 + 2 3.88e-07 T CACTTCCGGTTG GTGCGCTGCT chr2:232550398-232550898 - 40 3.88e-07 TGGGCCCGGG TACTTCCGGTTT TGCGCGGGGC chr1:43172076-43172576 + 53 3.88e-07 CGGCAAACCA TACTTCCGGTTT GTCGTTGCTA chr1:28088353-28088853 - 84 5.13e-07 CCGCT TACTTCCGGTTC CTAGCGATGC chr17:57849799-57850299 - 50 6.50e-07 CTGGAGCAGC CGCTTCCGGTTC CGGTAGCAGC chr1:20507949-20508449 - 27 6.50e-07 CCCCTTGCCC CGCTTCCGGTTC CGGCGTCGTG chr21:46286062-46286562 + 14 8.55e-07 GCCGCGGACC GACTTCCGGTTC GCTCAGCACT chr19:11435313-11435813 - 86 8.55e-07 CGT CACTTCCGGTCG TACGTTCCGC chr4:152779737-152780237 + 7 8.55e-07 CAACGC TACTTCCGGTCT CCTCACTTCC chr17:30906030-30906530 + 6 8.55e-07 CCATT GACTTCCGGTTC CTGCGTGCTG chr1:44213173-44213673 - 43 8.55e-07 CCGACAGAAA CACTTCCGGTCG GTGTTGTAGG chr12:110450055-11045055 + 59 1.11e-06 TACAGCGGAG CGCTTCCGGTCT GGCAGCCTGG chr19:8832101-8832601 + 16 1.11e-06 CCCGCGCTTC CGCTTCCGGTCT GGGGAGAGGT chr5:142024654-142025154 + 34 1.11e-06 AAAAAAAGTG AACTTCCGGTTT GCTTGCAAGA chr8:143281438-143281938 - 57 1.46e-06 CTTTCCGGTT TGCTTCCGGTTT TTTCCTCAGG chr1:43389617-43390117 + 58 1.46e-06 CCCTCCCACC AACTTCCGGTTC CTGCTGGGTG chr14:67359649-67360149 + 10 1.46e-06 TTTCACTTC CGCTTCCGGTTG TCACAGGCGA chr8:142717957-142718457 - 64 1.46e-06 CCTTTCAGTT TGCTTCCGGTTT CTTTCCCAGG chr5:110738752-110739252 + 41 1.75e-06 TTTCCAACGT GACTTCCGGTTG TCAGAATTTA chr3:119498180-119498680 - 88 1.75e-06 A GACTTCCGGTTG AGGGCGGGTT chr17:4940242-4940742 - 44 1.75e-06 TGAGATGAAG GACTTCCGGTCC TAAAAGGCCG chr19:36772817-36773317 + 72 1.75e-06 CAGGAAAACG TGCTTCCGGTTC TCGGCGGAAG chr19:12681637-12682137 - 58 2.08e-06 GTGATAAACC AACTTCCGGTCT TTCGCCCAAA chr9:85940763-85941263 + 32 2.08e-06 GAAAAAAGAT AACTTCCGGTCT CGCGATCGTC chr1:1615150-1615650 + 64 2.08e-06 CCGCGTGACG CACTTCCGGTGC TTGCCCTGCC chr6:57317393-57317893 + 24 2.08e-06 TAGTCACTTC CTCTTCCGGTTT CATATGAACT chr5:81301369-81301869 + 24 2.68e-06 GGGCACTATG TGCTTCCGGTCT CCAATACCGC chr11:45917639-45918139 + 50 2.68e-06 CCCTCCTTCC TGCTTCCGGTCT TAGGCCCGCC chr19:50376126-50376626 - 86 2.68e-06 ACG AACTTCCGGTCC GCTTAGGACC chr2:196799453-196799953 - 1 2.68e-06 GAAGGCGCTG CTCTTCCGGTTC chr5:149345136-149345636 - 73 3.16e-06 AGGAACGCTA TGCTTCCGGTTG CCCGATGGGC chr12:6493133-6493633 + 25 3.16e-06 CCCGCCTCAG TGCTTCCGGTCC GCCTGCCGGA chr19:5720087-5720587 + 23 3.58e-06 TCGTCTCCGC CTCTTCCGGTCT CCCACTTTAT chr19:43950898-43951398 + 81 4.37e-06 GGGTTGCGGG CACTTCCGGTCA GGCAGGCG chr2:24076212-24076712 + 65 4.37e-06 GAGTCCAAGA CACTTCCGGGCT CTGTACCGTA chr12:51172704-51173204 + 16 4.37e-06 GTCCCACGAT CACTTCCGGTCA CCCCTTCTCA chr6:7389575-7390075 + 34 4.37e-06 GGCGGTGAGG GGCTTCCGGTTG GGGTGGCAGG chr2:55269025-55269525 + 46 4.37e-06 GTCCCCGCCG GGCTTCCGGTCC CGCTGGAAAA chr8:33484925-33485425 - 49 4.37e-06 CTCAGCGTGC AACTTCCGGTCG GATCGCGGGC chr19:49580397-49580897 - 24 4.37e-06 GGGGCAGCTC TACTTCCGGTGC CTTCTGCTGG chr12:49567884-49568384 + 48 5.19e-06 GAGGTACGTC TACTTCCGGTTA ACGAACCAGG chr1:100132760-100133260 + 35 5.19e-06 CACCATCGGA TTCTTCCGGTTC TGCGGAGGAT chr3:180601881-180602381 + 32 5.19e-06 GACCCCAGAA CACTTCCGGGTG TAACTGGTTG chr16:74296589-74297089 - 20 5.19e-06 CCAGTTCCTC TTCTTCCGGTTC GTCAGCCCTC chr7:99919315-99919815 - 80 5.19e-06 ATACCCAGC AGCTTCCGGTCT TGCGCGCTCA chr19:55279896-55280396 - 37 5.19e-06 GTACGCCTGG CACTTCCGGGTG AAACCGTGCG chr11:18526680-18527180 + 85 5.19e-06 TCCACTACGT CACTTCCGGGCC GCCG chr19:3761735-3762235 - 53 5.19e-06 GTCTCCACGA CGCTTCCGGTGC CTCAAGGTCC chr3:15098912-15099412 - 62 5.91e-06 CTACCAGCTT GTCTTCCGGTTT CGTCGCCGCC chr5:83077349-83077849 - 42 5.91e-06 TCCGTGACTC TACTTCCGGTAT CTTCCAAAAC chr7:92245698-92246198 + 22 5.91e-06 GCTATGAAAT CGCTTCCGGGTT CACACCCTTT chr10:18659024-18659524 - 4 5.91e-06 TCTTCGGTTT CACTTCCGGTAG GAG chr1:155934240-155934740 + 17 6.79e-06 TACGCACAGC CTCTTCCGGTCG TGGGGCCGAG chr14:21383838-21384338 + 19 6.79e-06 ATGCCCTTTC CGCTTCCGGGTC CCAACAGCgt chr17:18315057-18315557 + 1 6.79e-06 . CGCTTCCGGGTC ACGCGGCGCG chr17:46922816-46923316 - 89 6.79e-06 . GGCTTCCGGTCG CAGGACCCTC chr11:72112474-72112974 - 2 6.79e-06 CTGGGTGAAG CGCTTCCGGGTC G chr12:57745062-57745562 + 19 6.79e-06 ATCTCTAGGG TACTTCCGGTGG GGAGAGGGGT chrX:153928079-153928579 - 64 6.79e-06 TGGCGGCAGT GTCTTCCGGTTC GCAAGCCCGC chr6:169751388-169751888 - 58 7.80e-06 CTACCTCCAT AACTTCCGGTGC CCCGCTGCGG chr7:44200680-44201180 + 29 7.80e-06 CGCTGCATTG TACTTCCGGGCT CACATTTCTG chr9:111630923-111631423 - 84 7.80e-06 TAGGC TGCTTCCGGTGT GTCACTGAAC chr20:31738964-31739464 + 12 7.80e-06 ACCTCCTTCT GACTTCCGGTAT TGCTGCGGTC chrX:71366023-71366523 + 80 7.80e-06 ACTGTTGTTT TATTTCCGGTCT ATGGGACCC chr1:230978766-230979266 + 70 8.88e-06 CGCGGCGCAA GTCTTCCGGTCT GGCGTCTGAC chrX:47836611-47837111 - 86 8.88e-06 AGC CGCTTCCGGTCA CTACCCCTAG chr13:52194233-52194733 + 23 8.88e-06 CGCTCTCCTC CGTTTCCGGTCT GGCTTGTTCC chr13:45464572-45465072 - 52 8.88e-06 TGGGTACGAC TATTTCCGGTTG AAACGTAGAA chr7:5822859-5823359 - 46 1.02e-05 CACGACGCCA TGCTTCCGGTTA GGCTACCCTG chr19:36666555-36667055 - 72 1.02e-05 TGTCCACAGC TACTTCCGGTAG GAGCCTCGCA chr7:108569513-108570013 - 45 1.02e-05 GGCTGTGCGC CACTTCCGGCTT CAACCCCCGA chr12:48105899-48106399 - 20 1.15e-05 CACCTAGCGA CTCTTCCGGTGC TGTGAAGGCG chr1:150293606-150294106 + 42 1.15e-05 CCGTAATTTC CGCTTCCGGTAG TGAGAACCCT chr14:21511156-21511656 + 15 1.15e-05 ACAGAAAAGT CATTTCCGGTGT CGCGCTTTCT chr21:25734806-25735306 + 70 1.15e-05 GGAGGGTAAG TGCTTCCGGGTC CCCTGGCACA chr11:62621943-62622443 + 20 1.15e-05 TTGTAGACTT GATTTCCGGTCC CACCGCCAGG chr16:1420557-1421057 - 29 1.28e-05 TATGGCGCCC GGTTTCCGGTTT CCGGCGACGG chr19:38374290-38374790 + 62 1.28e-05 GGCAAAAGCC AACTTCCGGTCA CCATCTTGAG chr12:76348204-76348704 - 51 1.28e-05 TTCGACTCCT GGCTTCCGGGTT TTCTCCCCGC chr5:121961599-121962099 + 58 1.28e-05 TGTTCTGTCT CAGTTCCGGTTT TCCCTTCCAA chr1:150321317-150321817 + 20 1.45e-05 GCGGTCAGAA GGTTTCCGGTTC CGGTGTAACG chr20:20017058-20017558 - 24 1.45e-05 GACGGGGTAC TGCTTCCGGGCT ACGAGTTGCT chr17:42773190-42773690 + 59 1.60e-05 CTTAGCCGGT AGCTTCCGGGTT TCCTGGGCTA chr15:40382678-40383178 - 47 1.60e-05 TTCAAATAGA AACTTCCGGTAG CTAGGCGGAA chr5:133051421-133051921 - 33 1.60e-05 ACATCAAAGA AACTTCCGGTAG TGGGGTGTCT chr6:27693785-27694285 - 37 1.60e-05 CCCCTGGCGT CATTTCCGGGTC CGCTCTGGAA chr19:14571811-14572311 + 71 1.76e-05 AGTCAGACAC AGCTTCCGGGTC ATTTAGGCAG chr12:69470130-69470630 - 40 1.76e-05 CTTGGAAAAG CACTTCCGGGGG AGCGGGGGAG chr3:14178550-14179050 + 20 1.76e-05 GGTTTCTCTC TATTTCCGGTGT ATTGTATCCT chr17:7572180-7572680 - 64 1.76e-05 AGCCTCCAGA GGCTTCCGGGCT CTGGGGGTTA chr1:200620580-200621080 - 38 1.76e-05 CAACCACCGG CACTTCCGGGGG GCGGGTGGAA chr19:39435664-39436164 - 73 1.99e-05 CCTAGCTTTC CTTTTCCGGTTG CGGCGCCGCG chr11:93783967-93784467 - 70 1.99e-05 TTCCCTAGAG CGCTTCCGGTGA ATCACGGTGC chr11:119018113-11901861 + 77 1.99e-05 CCGCTGTGAG TACTTCCGGGGC AAAAGGCGGA chr19:44071882-44072382 + 48 1.99e-05 GGGGTAGGGG CACTTCCGCTCC CGGGGGGCGA chr3:183884631-183885131 + 70 1.99e-05 GCTGCGCAAC TACTTCCGGGGC GAAGGCAACA chr16:89657416-89657916 + 77 2.19e-05 ACCCGGCGGG GACTTCCGGGGT CGCCGCCCCA chr8:27311314-27311814 + 66 2.39e-05 ACTGGAAACC TACTTCCGGCTG CAAATGGGAA chr8:74350128-74350628 - 49 2.39e-05 CCCCGCAAGG CGTTTCCGGGTT TTGAGGGGTA chr15:55196721-55197221 - 33 2.65e-05 GGAAGAAGGT AACTTCCGGTGA CGGGGTTGCA chr12:119667676-11966817 - 77 2.65e-05 ACCCCTCAGC GACTTCCGCTTC CGGCGACTCC chr19:58519640-58520140 + 42 2.65e-05 GGCCGAAGCA CGTTTCCGGTAT TTTTATGGCG chr19:34677034-34677534 - 80 2.65e-05 CGTGCCAAG GTCTTCCGGGTC ATTCCTGCGC chr17:18087671-18088171 + 59 2.65e-05 TGTTCTCTTT GGCTTCCGGGCG CACGCTACTC chr14:44961891-44962391 + 40 2.93e-05 ACGGCAAGTG GATTTCCGGGTC AAGAGGTCCG chr10:97401107-97401607 + 39 2.93e-05 CTTCTGGCGT CACTTCCGGATT CGTGTGCATT chr7:103297173-103297673 - 42 2.93e-05 ATGAAGGATG TGCTTCCGGGGT CGCGACCTGA chr15:75335800-75336300 - 48 2.93e-05 CGGGAATTTC TTTTTCCGGTCC CGCAGGGTCA chr13:30617633-30618133 - 75 3.23e-05 CTAGGAAGGC GGCTTCCGGCTT GAGTCCGCGG chr1:150487007-150487507 + 36 3.23e-05 TACATTTTCG GTCTTCCGGTCA GCCGGAACCA chr17:1463107-1463607 + 49 3.55e-05 ttggttctgt ggtttccggtgt gggttccggt chr19:4723723-4724223 + 39 3.55e-05 CATGAACGAC ATCTTCCGGTGG GTTAGGGAGA chr1:179882537-179883037 + 30 3.55e-05 CCGGCTAGAA GAGTTCCGGTCC GATTCTGCGA chr16:807577-808077 + 31 3.55e-05 CTTGGGAGAT AATTTCCGGGTC CCGGCAGGAA chr1:226944558-226945058 + 71 3.87e-05 GGAAGGTAGG TGTTTCCGGGTC ATTTGGAAAA chr3:129160952-129161452 - 77 3.87e-05 TACTCTCATT CACTTCCTGTCC CTTTCTTTTA chr9:36190642-36191142 + 74 3.87e-05 ACACGGGTAG GGCTTCCGCTTT ACCCGTCTCC chr7:139340030-139340530 + 70 3.87e-05 AAGGTCCGGC TGCTTCCGGTAA AAACCCACCA chr1:33127058-33127558 + 35 3.87e-05 TGAAGCCACG GTCTTCCGGTAG CGTAAAGTCA chr16:2682197-2682697 - 10 4.25e-05 CGGTAGGCGG AAGTTCCGGTCC CGAAAAGCA chr1:1375104-1375604 + 25 4.25e-05 GAAAGGCGAC GGTTTCCGGTTA GTGGAATCAC chr12:122266259-12226675 - 66 4.25e-05 AGCAGATTCC GGTTTCCGGGTT GGCGTGCGCT chr16:67872821-67873321 - 46 4.25e-05 CAACCGCCTC CACTTCCGGCAC CCACGAGCCG chr5:176448120-176448620 - 8 4.25e-05 CAGCCACAAC CACATCCGGTCT GAACGGC chr1:37989839-37990339 - 42 4.25e-05 AGTCCCGGGG CACTTCCGGCAC TCGCGGAACT chr19:1383558-1384058 + 62 4.63e-05 TCCCGGCTCC AGGTTCCGGTTT CCGCATGCGC chr17:28357388-28357888 + 19 4.63e-05 CGCTTAGCGT TACTTCCGGCGC GCGGCGGGCG chr1:66924920-66925420 - 89 4.63e-05 . GTCTTCCGGGCG GTACACTGCC chr1:234373224-234373724 - 10 4.63e-05 AGAGGGGCGG GACTTCCTGTTT CGCTTTTAT chr3:15427348-15427848 - 14 4.99e-05 AAGGCCGTGG GACTTCCGGCGT CGGGTAGGAA chr10:74826043-74826543 - 73 5.44e-05 CTGGGTCCGC CTCTTCCGGGCA CCTATTGGTC chr10:96129696-96130196 + 79 5.44e-05 GGCCTCCGTT CTCTTCCGCTTG TCTCAGGTAA chr16:30650436-30650936 - 23 5.91e-05 GCCGGTCCCC GTCTTCCGGGGT GGTGAGAAAC chr19:10194308-10194808 - 10 5.91e-05 GCTTTGGGTT CGTTTCCGGGGT CCCCTTCTT chr1:156740987-156741487 - 70 6.38e-05 GCTTCATGGT GTGTTCCGGTTT CCTTGATTTC chr11:2400275-2400775 + 68 6.38e-05 CAAATGCCGT CGTTTCCGGGGC TGCTTCCGAG chr19:58499269-58499769 - 19 6.38e-05 CCTCGGGGAC ACCTTCCGGTCC GAGGCAGGGT chr7:130205248-130205748 - 22 6.38e-05 GACTACCTAG TTCTTCCGGTAA CTTTAGAGCC chr6:49463063-49463563 + 85 6.38e-05 GTTAGATGCC CGTTTCCGCTTT CTTC chr6:34887830-34888330 + 12 6.87e-05 GCCAGGATCT TACTTCCTGTCG TCGCGCAGCG chr1:154182976-154183476 - 41 7.44e-05 GCGGGTTGGT GAGTTCCGGTAT TTCAGGGCGT chr2:3574953-3575453 + 84 7.44e-05 CTTCTCAGTG ATGTTCCGGTTT CCGCC chr16:690202-690702 - 14 8.03e-05 AGAAGAGGAC CACTTCCGGCGA GGGACGGGAA chr7:128476546-128477046 + 1 8.03e-05 . TGTTTCCGGCTC CGGTGTCATG chr2:183124124-183124624 - 19 8.03e-05 GGGGTTGCGT AACTTCCGGACC TGCGCTATGC chr14:30621969-30622469 + 79 8.03e-05 TTTGGCCCCG CCCTTCCGGGCT TTGCTTCCGG chr11:64268972-64269472 + 53 8.03e-05 CCCTCACCTC ACCTTCCGGTCG CAGCTCTAGC chr17:74203423-74203923 - 32 8.66e-05 ACGAGACTTC CGTTTCCGGGCA GTTAAACCCT chr2:112584277-112584777 - 68 8.66e-05 CCAGCCTGGT TTTTTCCGGTAG CCAATTGAAC chr17:80415116-80415616 - 71 8.66e-05 GAGATCCCTC CGCTTCCGCGCC GGAAACTGGG chr7:30594503-30595003 + 42 8.66e-05 TTCGGCGGGG TCCTTCCGGGTT TTGTGTCGAA chr1:155140249-155140749 - 85 8.66e-05 GGAG GACTTCCGGACG CCAACATCCG chr6:30557068-30557568 - 1 9.30e-05 GCGGGGATTC TGTTTCCGCTTC chr10:22552767-22553267 + 38 9.30e-05 AGATGAATGC CACTTCAGGTTC ACCCCAGCAG chr1:173714620-173715120 - 44 9.30e-05 ATCCGCCAAG GGGTTCCGGTGC GGCTCCGGAA chr6:127343088-127343588 + 73 1.29e-04 TGGTGACTTC CTTTTCCGCTCC CCTACACACG chr16:11915835-11916335 + 41 1.29e-04 TGGCCGCCCC CGTTTCCGGCTA TTTAGCGCGG chr19:44259548-44260048 + 86 1.38e-04 GGCGGTAGCC TGTTTCCGCTCG GGC chr6:31958779-31959279 + 39 1.38e-04 CCCAGGCGCG CACTTCCGCCCG GCCTTCCACC chr1:165768697-165769197 - 9 1.38e-04 CCGATACGAG CCTTTCCGGTGC TATGCCCC chr12:6663085-6663585 + 66 1.46e-04 GGCTGTAGCC CGCTTCCGCCCT TACAGACACC chr7:97117323-97117823 + 43 1.46e-04 GCGGAGCTTG GGTTTCCGGGAG GACCTGATTG chr15:65610925-65611425 - 45 1.46e-04 CGCGGCCTTA TAGTTCCGGCTG TGGCGCGCGG chr10:87878916-87879416 - 50 1.56e-04 TGATAAGACT GGTTTCCTGTTT CAGAACTCTC chr5:92552209-92552709 - 88 1.56e-04 T TGCTTCCTGTGG CTATTTTTAG chr3:48439898-48440398 + 68 1.65e-04 CCTGGAGCGC CGCATCCGGTAG CGAGAGTTCA chr12:34022154-34022654 + 31 1.75e-04 TGAGAGGGTA ATCATCCGGTCC GTTATCTAAA chr12:38316440-38316940 + 38 1.75e-04 GGAGAGGGTA ATCATCCGGTCC GTTATCTAAA chr6:90587028-90587528 - 47 1.75e-04 CTCTCGCGGT ATCATCCGGTTG CTGAGGCCCT chr12:110048404-11004890 + 27 1.75e-04 GTCCTGGTCT AAGTTCCGCTTC TGCCTAAGAT chr17:63773561-63774061 - 52 1.75e-04 GGCCACCTTT AGCTTCCGGAGC ACCGGTTCCG chr1:154973975-154974475 + 20 1.86e-04 CCCGGGAGAG GGGTTCCGGGGT GAAAGAGTGA chr3:57597454-57597954 + 22 1.86e-04 CAGGGTGAGA CGCTTCCGCCCG GATGAAGGTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:159263006-159263506 5.7e-08 45_[+1]_43 chr15:65517429-65517929 1.2e-07 53_[+1]_35 chr16:667901-668401 1.2e-07 [-1]_88 chr19:16197635-16198135 1.2e-07 70_[-1]_18 chr11:64317420-64317920 1.2e-07 6_[-1]_82 chr17:50372899-50373399 1.9e-07 84_[+1]_4 chr19:49451588-49452088 1.9e-07 33_[+1]_55 chr15:90265356-90265856 1.9e-07 85_[+1]_3 chr3:14651489-14651989 3.9e-07 61_[+1]_27 chr6:36874590-36875090 3.9e-07 60_[+1]_28 chr17:59707369-59707869 3.9e-07 64_[-1]_24 chr16:84186779-84187279 3.9e-07 73_[-1]_15 chr6:28136607-28137107 3.9e-07 26_[-1]_62 chr14:74881627-74882127 3.9e-07 64_[+1]_24 chr16:77190860-77191360 3.9e-07 64_[-1]_24 chr15:89893816-89894316 3.9e-07 1_[+1]_87 chr2:232550398-232550898 3.9e-07 39_[-1]_49 chr1:43172076-43172576 3.9e-07 52_[+1]_36 chr1:28088353-28088853 5.1e-07 83_[-1]_5 chr17:57849799-57850299 6.5e-07 49_[-1]_39 chr1:20507949-20508449 6.5e-07 26_[-1]_62 chr21:46286062-46286562 8.5e-07 13_[+1]_75 chr19:11435313-11435813 8.5e-07 85_[-1]_3 chr4:152779737-152780237 8.5e-07 6_[+1]_82 chr17:30906030-30906530 8.5e-07 5_[+1]_83 chr1:44213173-44213673 8.5e-07 42_[-1]_46 chr12:110450055-11045055 1.1e-06 58_[+1]_30 chr19:8832101-8832601 1.1e-06 15_[+1]_73 chr5:142024654-142025154 1.1e-06 33_[+1]_55 chr8:143281438-143281938 1.5e-06 56_[-1]_32 chr1:43389617-43390117 1.5e-06 57_[+1]_31 chr14:67359649-67360149 1.5e-06 9_[+1]_79 chr8:142717957-142718457 1.5e-06 63_[-1]_25 chr5:110738752-110739252 1.7e-06 40_[+1]_48 chr3:119498180-119498680 1.7e-06 87_[-1]_1 chr17:4940242-4940742 1.7e-06 43_[-1]_45 chr19:36772817-36773317 1.7e-06 71_[+1]_17 chr19:12681637-12682137 2.1e-06 57_[-1]_31 chr9:85940763-85941263 2.1e-06 31_[+1]_57 chr1:1615150-1615650 2.1e-06 63_[+1]_25 chr6:57317393-57317893 2.1e-06 23_[+1]_65 chr5:81301369-81301869 2.7e-06 23_[+1]_65 chr11:45917639-45918139 2.7e-06 49_[+1]_39 chr19:50376126-50376626 2.7e-06 85_[-1]_3 chr2:196799453-196799953 2.7e-06 [-1]_88 chr5:149345136-149345636 3.2e-06 72_[-1]_16 chr12:6493133-6493633 3.2e-06 24_[+1]_64 chr19:5720087-5720587 3.6e-06 22_[+1]_66 chr19:43950898-43951398 4.4e-06 80_[+1]_8 chr2:24076212-24076712 4.4e-06 64_[+1]_24 chr12:51172704-51173204 4.4e-06 15_[+1]_73 chr6:7389575-7390075 4.4e-06 33_[+1]_55 chr2:55269025-55269525 4.4e-06 45_[+1]_43 chr8:33484925-33485425 4.4e-06 48_[-1]_40 chr19:49580397-49580897 4.4e-06 23_[-1]_65 chr12:49567884-49568384 5.2e-06 47_[+1]_41 chr1:100132760-100133260 5.2e-06 34_[+1]_54 chr3:180601881-180602381 5.2e-06 31_[+1]_57 chr16:74296589-74297089 5.2e-06 19_[-1]_69 chr7:99919315-99919815 5.2e-06 79_[-1]_9 chr19:55279896-55280396 5.2e-06 36_[-1]_52 chr11:18526680-18527180 5.2e-06 84_[+1]_4 chr19:3761735-3762235 5.2e-06 52_[-1]_36 chr3:15098912-15099412 5.9e-06 61_[-1]_27 chr5:83077349-83077849 5.9e-06 41_[-1]_47 chr7:92245698-92246198 5.9e-06 21_[+1]_67 chr10:18659024-18659524 5.9e-06 3_[-1]_85 chr1:155934240-155934740 6.8e-06 16_[+1]_72 chr14:21383838-21384338 6.8e-06 18_[+1]_70 chr17:18315057-18315557 6.8e-06 [+1]_88 chr17:46922816-46923316 6.8e-06 88_[-1] chr11:72112474-72112974 6.8e-06 1_[-1]_87 chr12:57745062-57745562 6.8e-06 18_[+1]_70 chrX:153928079-153928579 6.8e-06 63_[-1]_25 chr6:169751388-169751888 7.8e-06 57_[-1]_31 chr7:44200680-44201180 7.8e-06 28_[+1]_60 chr9:111630923-111631423 7.8e-06 83_[-1]_5 chr20:31738964-31739464 7.8e-06 11_[+1]_77 chrX:71366023-71366523 7.8e-06 79_[+1]_9 chr1:230978766-230979266 8.9e-06 69_[+1]_19 chrX:47836611-47837111 8.9e-06 85_[-1]_3 chr13:52194233-52194733 8.9e-06 22_[+1]_66 chr13:45464572-45465072 8.9e-06 51_[-1]_37 chr7:5822859-5823359 1e-05 45_[-1]_43 chr19:36666555-36667055 1e-05 71_[-1]_17 chr7:108569513-108570013 1e-05 44_[-1]_44 chr12:48105899-48106399 1.1e-05 19_[-1]_69 chr1:150293606-150294106 1.1e-05 41_[+1]_47 chr14:21511156-21511656 1.1e-05 14_[+1]_74 chr21:25734806-25735306 1.1e-05 69_[+1]_19 chr11:62621943-62622443 1.1e-05 19_[+1]_69 chr16:1420557-1421057 1.3e-05 28_[-1]_60 chr19:38374290-38374790 1.3e-05 61_[+1]_27 chr12:76348204-76348704 1.3e-05 50_[-1]_38 chr5:121961599-121962099 1.3e-05 57_[+1]_31 chr1:150321317-150321817 1.4e-05 19_[+1]_69 chr20:20017058-20017558 1.4e-05 23_[-1]_65 chr17:42773190-42773690 1.6e-05 58_[+1]_30 chr15:40382678-40383178 1.6e-05 46_[-1]_42 chr5:133051421-133051921 1.6e-05 32_[-1]_56 chr6:27693785-27694285 1.6e-05 36_[-1]_52 chr19:14571811-14572311 1.8e-05 70_[+1]_18 chr12:69470130-69470630 1.8e-05 39_[-1]_49 chr3:14178550-14179050 1.8e-05 19_[+1]_69 chr17:7572180-7572680 1.8e-05 63_[-1]_25 chr1:200620580-200621080 1.8e-05 37_[-1]_51 chr19:39435664-39436164 2e-05 72_[-1]_16 chr11:93783967-93784467 2e-05 69_[-1]_19 chr11:119018113-11901861 2e-05 76_[+1]_12 chr19:44071882-44072382 2e-05 47_[+1]_41 chr3:183884631-183885131 2e-05 69_[+1]_19 chr16:89657416-89657916 2.2e-05 76_[+1]_12 chr8:27311314-27311814 2.4e-05 65_[+1]_23 chr8:74350128-74350628 2.4e-05 48_[-1]_40 chr15:55196721-55197221 2.7e-05 32_[-1]_56 chr12:119667676-11966817 2.7e-05 76_[-1]_12 chr19:58519640-58520140 2.7e-05 41_[+1]_47 chr19:34677034-34677534 2.7e-05 79_[-1]_9 chr17:18087671-18088171 2.7e-05 58_[+1]_30 chr14:44961891-44962391 2.9e-05 39_[+1]_49 chr10:97401107-97401607 2.9e-05 38_[+1]_50 chr7:103297173-103297673 2.9e-05 41_[-1]_47 chr15:75335800-75336300 2.9e-05 47_[-1]_41 chr13:30617633-30618133 3.2e-05 74_[-1]_14 chr1:150487007-150487507 3.2e-05 35_[+1]_53 chr17:1463107-1463607 3.5e-05 48_[+1]_40 chr19:4723723-4724223 3.5e-05 38_[+1]_50 chr1:179882537-179883037 3.5e-05 29_[+1]_59 chr16:807577-808077 3.5e-05 30_[+1]_58 chr1:226944558-226945058 3.9e-05 70_[+1]_18 chr3:129160952-129161452 3.9e-05 76_[-1]_12 chr9:36190642-36191142 3.9e-05 73_[+1]_15 chr7:139340030-139340530 3.9e-05 69_[+1]_19 chr1:33127058-33127558 3.9e-05 34_[+1]_54 chr16:2682197-2682697 4.3e-05 9_[-1]_79 chr1:1375104-1375604 4.3e-05 24_[+1]_64 chr12:122266259-12226675 4.3e-05 65_[-1]_23 chr16:67872821-67873321 4.3e-05 45_[-1]_43 chr5:176448120-176448620 4.3e-05 7_[-1]_81 chr1:37989839-37990339 4.3e-05 41_[-1]_47 chr19:1383558-1384058 4.6e-05 61_[+1]_27 chr17:28357388-28357888 4.6e-05 18_[+1]_70 chr1:66924920-66925420 4.6e-05 88_[-1] chr1:234373224-234373724 4.6e-05 9_[-1]_79 chr3:15427348-15427848 5e-05 13_[-1]_75 chr10:74826043-74826543 5.4e-05 72_[-1]_16 chr10:96129696-96130196 5.4e-05 78_[+1]_10 chr16:30650436-30650936 5.9e-05 22_[-1]_66 chr19:10194308-10194808 5.9e-05 9_[-1]_79 chr1:156740987-156741487 6.4e-05 69_[-1]_19 chr11:2400275-2400775 6.4e-05 67_[+1]_21 chr19:58499269-58499769 6.4e-05 18_[-1]_70 chr7:130205248-130205748 6.4e-05 21_[-1]_67 chr6:49463063-49463563 6.4e-05 84_[+1]_4 chr6:34887830-34888330 6.9e-05 11_[+1]_77 chr1:154182976-154183476 7.4e-05 40_[-1]_48 chr2:3574953-3575453 7.4e-05 83_[+1]_5 chr16:690202-690702 8e-05 13_[-1]_75 chr7:128476546-128477046 8e-05 [+1]_88 chr2:183124124-183124624 8e-05 18_[-1]_70 chr14:30621969-30622469 8e-05 78_[+1]_10 chr11:64268972-64269472 8e-05 52_[+1]_36 chr17:74203423-74203923 8.7e-05 31_[-1]_57 chr2:112584277-112584777 8.7e-05 67_[-1]_21 chr17:80415116-80415616 8.7e-05 70_[-1]_18 chr7:30594503-30595003 8.7e-05 41_[+1]_47 chr1:155140249-155140749 8.7e-05 84_[-1]_4 chr6:30557068-30557568 9.3e-05 [-1]_88 chr10:22552767-22553267 9.3e-05 37_[+1]_51 chr1:173714620-173715120 9.3e-05 43_[-1]_45 chr6:127343088-127343588 0.00013 72_[+1]_16 chr16:11915835-11916335 0.00013 40_[+1]_48 chr19:44259548-44260048 0.00014 85_[+1]_3 chr6:31958779-31959279 0.00014 38_[+1]_50 chr1:165768697-165769197 0.00014 8_[-1]_80 chr12:6663085-6663585 0.00015 65_[+1]_23 chr7:97117323-97117823 0.00015 42_[+1]_46 chr15:65610925-65611425 0.00015 44_[-1]_44 chr10:87878916-87879416 0.00016 49_[-1]_39 chr5:92552209-92552709 0.00016 87_[-1]_1 chr3:48439898-48440398 0.00017 67_[+1]_21 chr12:34022154-34022654 0.00018 30_[+1]_58 chr12:38316440-38316940 0.00018 37_[+1]_51 chr6:90587028-90587528 0.00018 46_[-1]_42 chr12:110048404-11004890 0.00018 26_[+1]_62 chr17:63773561-63774061 0.00018 51_[-1]_37 chr1:154973975-154974475 0.00019 19_[+1]_69 chr3:57597454-57597954 0.00019 21_[+1]_67 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BRCTTCCGGTYB width=12 seqs=188 chr5:159263006-159263506 ( 46) CACTTCCGGTTT 1 chr15:65517429-65517929 ( 54) CACTTCCGGTTC 1 chr16:667901-668401 ( 1) CACTTCCGGTTC 1 chr19:16197635-16198135 ( 71) CACTTCCGGTTC 1 chr11:64317420-64317920 ( 7) CACTTCCGGTTC 1 chr17:50372899-50373399 ( 85) CACTTCCGGTCT 1 chr19:49451588-49452088 ( 34) CACTTCCGGTCT 1 chr15:90265356-90265856 ( 86) CACTTCCGGTCT 1 chr3:14651489-14651989 ( 62) CACTTCCGGTTG 1 chr6:36874590-36875090 ( 61) CACTTCCGGTCC 1 chr17:59707369-59707869 ( 65) CACTTCCGGTCC 1 chr16:84186779-84187279 ( 74) CACTTCCGGTCC 1 chr6:28136607-28137107 ( 27) CACTTCCGGTTG 1 chr14:74881627-74882127 ( 65) CACTTCCGGTTG 1 chr16:77190860-77191360 ( 65) CACTTCCGGTTG 1 chr15:89893816-89894316 ( 2) CACTTCCGGTTG 1 chr2:232550398-232550898 ( 40) TACTTCCGGTTT 1 chr1:43172076-43172576 ( 53) TACTTCCGGTTT 1 chr1:28088353-28088853 ( 84) TACTTCCGGTTC 1 chr17:57849799-57850299 ( 50) CGCTTCCGGTTC 1 chr1:20507949-20508449 ( 27) CGCTTCCGGTTC 1 chr21:46286062-46286562 ( 14) GACTTCCGGTTC 1 chr19:11435313-11435813 ( 86) CACTTCCGGTCG 1 chr4:152779737-152780237 ( 7) TACTTCCGGTCT 1 chr17:30906030-30906530 ( 6) GACTTCCGGTTC 1 chr1:44213173-44213673 ( 43) CACTTCCGGTCG 1 chr12:110450055-11045055 ( 59) CGCTTCCGGTCT 1 chr19:8832101-8832601 ( 16) CGCTTCCGGTCT 1 chr5:142024654-142025154 ( 34) AACTTCCGGTTT 1 chr8:143281438-143281938 ( 57) TGCTTCCGGTTT 1 chr1:43389617-43390117 ( 58) AACTTCCGGTTC 1 chr14:67359649-67360149 ( 10) CGCTTCCGGTTG 1 chr8:142717957-142718457 ( 64) TGCTTCCGGTTT 1 chr5:110738752-110739252 ( 41) GACTTCCGGTTG 1 chr3:119498180-119498680 ( 88) GACTTCCGGTTG 1 chr17:4940242-4940742 ( 44) GACTTCCGGTCC 1 chr19:36772817-36773317 ( 72) TGCTTCCGGTTC 1 chr19:12681637-12682137 ( 58) AACTTCCGGTCT 1 chr9:85940763-85941263 ( 32) AACTTCCGGTCT 1 chr1:1615150-1615650 ( 64) CACTTCCGGTGC 1 chr6:57317393-57317893 ( 24) CTCTTCCGGTTT 1 chr5:81301369-81301869 ( 24) TGCTTCCGGTCT 1 chr11:45917639-45918139 ( 50) TGCTTCCGGTCT 1 chr19:50376126-50376626 ( 86) AACTTCCGGTCC 1 chr2:196799453-196799953 ( 1) CTCTTCCGGTTC 1 chr5:149345136-149345636 ( 73) TGCTTCCGGTTG 1 chr12:6493133-6493633 ( 25) TGCTTCCGGTCC 1 chr19:5720087-5720587 ( 23) CTCTTCCGGTCT 1 chr19:43950898-43951398 ( 81) CACTTCCGGTCA 1 chr2:24076212-24076712 ( 65) CACTTCCGGGCT 1 chr12:51172704-51173204 ( 16) CACTTCCGGTCA 1 chr6:7389575-7390075 ( 34) GGCTTCCGGTTG 1 chr2:55269025-55269525 ( 46) GGCTTCCGGTCC 1 chr8:33484925-33485425 ( 49) AACTTCCGGTCG 1 chr19:49580397-49580897 ( 24) TACTTCCGGTGC 1 chr12:49567884-49568384 ( 48) TACTTCCGGTTA 1 chr1:100132760-100133260 ( 35) TTCTTCCGGTTC 1 chr3:180601881-180602381 ( 32) CACTTCCGGGTG 1 chr16:74296589-74297089 ( 20) TTCTTCCGGTTC 1 chr7:99919315-99919815 ( 80) AGCTTCCGGTCT 1 chr19:55279896-55280396 ( 37) CACTTCCGGGTG 1 chr11:18526680-18527180 ( 85) CACTTCCGGGCC 1 chr19:3761735-3762235 ( 53) CGCTTCCGGTGC 1 chr3:15098912-15099412 ( 62) GTCTTCCGGTTT 1 chr5:83077349-83077849 ( 42) TACTTCCGGTAT 1 chr7:92245698-92246198 ( 22) CGCTTCCGGGTT 1 chr10:18659024-18659524 ( 4) CACTTCCGGTAG 1 chr1:155934240-155934740 ( 17) CTCTTCCGGTCG 1 chr14:21383838-21384338 ( 19) CGCTTCCGGGTC 1 chr17:18315057-18315557 ( 1) CGCTTCCGGGTC 1 chr17:46922816-46923316 ( 89) GGCTTCCGGTCG 1 chr11:72112474-72112974 ( 2) CGCTTCCGGGTC 1 chr12:57745062-57745562 ( 19) TACTTCCGGTGG 1 chrX:153928079-153928579 ( 64) GTCTTCCGGTTC 1 chr6:169751388-169751888 ( 58) AACTTCCGGTGC 1 chr7:44200680-44201180 ( 29) TACTTCCGGGCT 1 chr9:111630923-111631423 ( 84) TGCTTCCGGTGT 1 chr20:31738964-31739464 ( 12) GACTTCCGGTAT 1 chrX:71366023-71366523 ( 80) TATTTCCGGTCT 1 chr1:230978766-230979266 ( 70) GTCTTCCGGTCT 1 chrX:47836611-47837111 ( 86) CGCTTCCGGTCA 1 chr13:52194233-52194733 ( 23) CGTTTCCGGTCT 1 chr13:45464572-45465072 ( 52) TATTTCCGGTTG 1 chr7:5822859-5823359 ( 46) TGCTTCCGGTTA 1 chr19:36666555-36667055 ( 72) TACTTCCGGTAG 1 chr7:108569513-108570013 ( 45) CACTTCCGGCTT 1 chr12:48105899-48106399 ( 20) CTCTTCCGGTGC 1 chr1:150293606-150294106 ( 42) CGCTTCCGGTAG 1 chr14:21511156-21511656 ( 15) CATTTCCGGTGT 1 chr21:25734806-25735306 ( 70) TGCTTCCGGGTC 1 chr11:62621943-62622443 ( 20) GATTTCCGGTCC 1 chr16:1420557-1421057 ( 29) GGTTTCCGGTTT 1 chr19:38374290-38374790 ( 62) AACTTCCGGTCA 1 chr12:76348204-76348704 ( 51) GGCTTCCGGGTT 1 chr5:121961599-121962099 ( 58) CAGTTCCGGTTT 1 chr1:150321317-150321817 ( 20) GGTTTCCGGTTC 1 chr20:20017058-20017558 ( 24) TGCTTCCGGGCT 1 chr17:42773190-42773690 ( 59) AGCTTCCGGGTT 1 chr15:40382678-40383178 ( 47) AACTTCCGGTAG 1 chr5:133051421-133051921 ( 33) AACTTCCGGTAG 1 chr6:27693785-27694285 ( 37) CATTTCCGGGTC 1 chr19:14571811-14572311 ( 71) AGCTTCCGGGTC 1 chr12:69470130-69470630 ( 40) CACTTCCGGGGG 1 chr3:14178550-14179050 ( 20) TATTTCCGGTGT 1 chr17:7572180-7572680 ( 64) GGCTTCCGGGCT 1 chr1:200620580-200621080 ( 38) CACTTCCGGGGG 1 chr19:39435664-39436164 ( 73) CTTTTCCGGTTG 1 chr11:93783967-93784467 ( 70) CGCTTCCGGTGA 1 chr11:119018113-11901861 ( 77) TACTTCCGGGGC 1 chr19:44071882-44072382 ( 48) CACTTCCGCTCC 1 chr3:183884631-183885131 ( 70) TACTTCCGGGGC 1 chr16:89657416-89657916 ( 77) GACTTCCGGGGT 1 chr8:27311314-27311814 ( 66) TACTTCCGGCTG 1 chr8:74350128-74350628 ( 49) CGTTTCCGGGTT 1 chr15:55196721-55197221 ( 33) AACTTCCGGTGA 1 chr12:119667676-11966817 ( 77) GACTTCCGCTTC 1 chr19:58519640-58520140 ( 42) CGTTTCCGGTAT 1 chr19:34677034-34677534 ( 80) GTCTTCCGGGTC 1 chr17:18087671-18088171 ( 59) GGCTTCCGGGCG 1 chr14:44961891-44962391 ( 40) GATTTCCGGGTC 1 chr10:97401107-97401607 ( 39) CACTTCCGGATT 1 chr7:103297173-103297673 ( 42) TGCTTCCGGGGT 1 chr15:75335800-75336300 ( 48) TTTTTCCGGTCC 1 chr13:30617633-30618133 ( 75) GGCTTCCGGCTT 1 chr1:150487007-150487507 ( 36) GTCTTCCGGTCA 1 chr17:1463107-1463607 ( 49) GGTTTCCGGTGT 1 chr19:4723723-4724223 ( 39) ATCTTCCGGTGG 1 chr1:179882537-179883037 ( 30) GAGTTCCGGTCC 1 chr16:807577-808077 ( 31) AATTTCCGGGTC 1 chr1:226944558-226945058 ( 71) TGTTTCCGGGTC 1 chr3:129160952-129161452 ( 77) CACTTCCTGTCC 1 chr9:36190642-36191142 ( 74) GGCTTCCGCTTT 1 chr7:139340030-139340530 ( 70) TGCTTCCGGTAA 1 chr1:33127058-33127558 ( 35) GTCTTCCGGTAG 1 chr16:2682197-2682697 ( 10) AAGTTCCGGTCC 1 chr1:1375104-1375604 ( 25) GGTTTCCGGTTA 1 chr12:122266259-12226675 ( 66) GGTTTCCGGGTT 1 chr16:67872821-67873321 ( 46) CACTTCCGGCAC 1 chr5:176448120-176448620 ( 8) CACATCCGGTCT 1 chr1:37989839-37990339 ( 42) CACTTCCGGCAC 1 chr19:1383558-1384058 ( 62) AGGTTCCGGTTT 1 chr17:28357388-28357888 ( 19) TACTTCCGGCGC 1 chr1:66924920-66925420 ( 89) GTCTTCCGGGCG 1 chr1:234373224-234373724 ( 10) GACTTCCTGTTT 1 chr3:15427348-15427848 ( 14) GACTTCCGGCGT 1 chr10:74826043-74826543 ( 73) CTCTTCCGGGCA 1 chr10:96129696-96130196 ( 79) CTCTTCCGCTTG 1 chr16:30650436-30650936 ( 23) GTCTTCCGGGGT 1 chr19:10194308-10194808 ( 10) CGTTTCCGGGGT 1 chr1:156740987-156741487 ( 70) GTGTTCCGGTTT 1 chr11:2400275-2400775 ( 68) CGTTTCCGGGGC 1 chr19:58499269-58499769 ( 19) ACCTTCCGGTCC 1 chr7:130205248-130205748 ( 22) TTCTTCCGGTAA 1 chr6:49463063-49463563 ( 85) CGTTTCCGCTTT 1 chr6:34887830-34888330 ( 12) TACTTCCTGTCG 1 chr1:154182976-154183476 ( 41) GAGTTCCGGTAT 1 chr2:3574953-3575453 ( 84) ATGTTCCGGTTT 1 chr16:690202-690702 ( 14) CACTTCCGGCGA 1 chr7:128476546-128477046 ( 1) TGTTTCCGGCTC 1 chr2:183124124-183124624 ( 19) AACTTCCGGACC 1 chr14:30621969-30622469 ( 79) CCCTTCCGGGCT 1 chr11:64268972-64269472 ( 53) ACCTTCCGGTCG 1 chr17:74203423-74203923 ( 32) CGTTTCCGGGCA 1 chr2:112584277-112584777 ( 68) TTTTTCCGGTAG 1 chr17:80415116-80415616 ( 71) CGCTTCCGCGCC 1 chr7:30594503-30595003 ( 42) TCCTTCCGGGTT 1 chr1:155140249-155140749 ( 85) GACTTCCGGACG 1 chr6:30557068-30557568 ( 1) TGTTTCCGCTTC 1 chr10:22552767-22553267 ( 38) CACTTCAGGTTC 1 chr1:173714620-173715120 ( 44) GGGTTCCGGTGC 1 chr6:127343088-127343588 ( 73) CTTTTCCGCTCC 1 chr16:11915835-11916335 ( 41) CGTTTCCGGCTA 1 chr19:44259548-44260048 ( 86) TGTTTCCGCTCG 1 chr6:31958779-31959279 ( 39) CACTTCCGCCCG 1 chr1:165768697-165769197 ( 9) CCTTTCCGGTGC 1 chr12:6663085-6663585 ( 66) CGCTTCCGCCCT 1 chr7:97117323-97117823 ( 43) GGTTTCCGGGAG 1 chr15:65610925-65611425 ( 45) TAGTTCCGGCTG 1 chr10:87878916-87879416 ( 50) GGTTTCCTGTTT 1 chr5:92552209-92552709 ( 88) TGCTTCCTGTGG 1 chr3:48439898-48440398 ( 68) CGCATCCGGTAG 1 chr12:34022154-34022654 ( 31) ATCATCCGGTCC 1 chr12:38316440-38316940 ( 38) ATCATCCGGTCC 1 chr6:90587028-90587528 ( 47) ATCATCCGGTTG 1 chr12:110048404-11004890 ( 27) AAGTTCCGCTTC 1 chr17:63773561-63774061 ( 52) AGCTTCCGGAGC 1 chr1:154973975-154974475 ( 20) GGGTTCCGGGGT 1 chr3:57597454-57597954 ( 22) CGCTTCCGCCCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 8.57148 E= 6.7e-153 -67 59 -31 0 107 -335 35 -62 -1420 151 -221 -43 -310 -1420 -1420 209 -1420 -1420 -1420 213 -1420 188 -1420 -1420 -542 187 -1420 -1420 -1420 -1420 184 -310 -1420 -197 178 -1420 -343 -186 -35 160 -134 28 -77 88 -143 35 -18 53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 188 E= 6.7e-153 0.143617 0.409574 0.218085 0.228723 0.478723 0.026596 0.345745 0.148936 0.000000 0.771277 0.058511 0.170213 0.026596 0.000000 0.000000 0.973404 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.005319 0.994681 0.000000 0.000000 0.000000 0.000000 0.973404 0.026596 0.000000 0.069149 0.930851 0.000000 0.021277 0.074468 0.212766 0.691489 0.090426 0.329787 0.159574 0.420213 0.085106 0.345745 0.239362 0.329787 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BRCTTCCGGTYB MEME-1 regular expression -------------------------------------------------------------------------------- [CTG][AG]CTTCCGG[TG][TC][CTG] -------------------------------------------------------------------------------- Time 741.99 secs. ******************************************************************************** ******************************************************************************** MOTIF GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 width = 32 sites = 17 llr = 621 E-value = 1.3e-136 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 Description -------------------------------------------------------------------------------- Simplified A 1:::9::2:1::1:::a9::1:::9::1:72: pos.-specific C :189:::8::::9:9:::a29a:1:aa:9::: probability G 99:::aa::9a::::a:::1:::91::::25a matrix T ::211:::a::a1a1::1:81:a::::9114: bits 2.1 * * * * * 1.9 ** * ** * ** * ** ** * 1.7 *** * ** * **** ** **** * 1.5 * **** **** ****** ******** * Relative 1.3 ******************* ********* * Entropy 1.1 ****************************** * (52.7 bits) 0.9 ****************************** * 0.6 ****************************** * 0.4 ******************************** 0.2 ******************************** 0.0 -------------------------------- Multilevel GGCCAGGCTGGTCTCGAACTCCTGACCTCAGG consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- -------------------------------- chr12:124922496-12492299 + 52 1.12e-19 tcagcatgtt ggccaggctggtctcgaactcctgacctcagg tgatctgcac chr10:23420805-23421305 + 16 2.07e-19 tcactatgtt ggccaggctggtctcgaactcctgacctcatg atccacctgc chr17:1258901-1259401 + 61 3.02e-19 tcgccatgtt ggccaggctggtctcgaactcctgacctcaag agatccgc chr16:30598283-30598783 - 32 6.25e-19 TCACCATGTT GGTCAGGCTGGTCTCGAACTCCTGACCTCAGG TGATCTGCCT chr16:25055673-25056173 - 29 1.03e-18 TCATCAGGTT GGCCAGGCTGGTCTCGAACCCCTGACCTCAGG TGATCCACCC chr10:5853639-5854139 - 49 1.83e-18 TTGCCATGTT GCCCAGGCTGGTCTCGAACTCCTGACCTCAGG TGATCTACCC chr6:30907512-30908012 + 14 3.29e-18 tcaccatgtt ggccaggatggtctcgaactcctgacctcggg tgattcgccg chr19:39033019-39033519 - 35 8.96e-18 TCACCATGTT GGCCAGGCTGGTCTCGAACTTCTGACCTCAAG CGATCCGCCT chr5:181215948-181216448 + 40 1.85e-17 tcaccacgtt ggtcaggctggtctcgaacgcctgacctcagg tgatccaccc chr5:181174436-181174936 + 30 1.85e-17 tcaccatgtt ggttaggctggtctcgaactcctgacctcatg atccacccgt chr5:10543711-10544211 - 37 2.05e-17 TCACCATGTT GGCCAGGCTGGTCTCGAACCACTGACCTCAGG TAATCCACCC chr6:27544050-27544550 + 47 6.43e-17 ccatcatgtt agccaggatggtctcgatctcctgacctcatg atccacccgc chr5:181218376-181218876 - 33 1.76e-16 TCACCATTTT AGCCAGGATGGTCTCGATCTCCTGACCTCGTG ATCCGCCAGC chr16:75445725-75446225 - 32 4.33e-16 TCACCATCTT GCCCAGGCTGGTCTTGAACTCCTGACCTTGTG ATCCACCCGC chr19:36070135-36070635 + 29 4.33e-16 ttaccatgtt ggcctggctggtctcgaactcctgacctttag tgatccatcc chr10:8702990-8703490 - 13 1.10e-15 TCACTATGTT GGCCAGGCTAGTATCGAACTCCTCACCTCGTG ATCCACCCAC chr1:150876802-150877302 - 42 1.50e-15 TCGCCATGTT GGCCAGGCTGGTTTCGAACCCCTGGCCACAGG TGATCCGGCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:124922496-12492299 1.1e-19 51_[+2]_17 chr10:23420805-23421305 2.1e-19 15_[+2]_53 chr17:1258901-1259401 3e-19 60_[+2]_8 chr16:30598283-30598783 6.3e-19 31_[-2]_37 chr16:25055673-25056173 1e-18 28_[-2]_40 chr10:5853639-5854139 1.8e-18 48_[-2]_20 chr6:30907512-30908012 3.3e-18 13_[+2]_55 chr19:39033019-39033519 9e-18 34_[-2]_34 chr5:181215948-181216448 1.8e-17 39_[+2]_29 chr5:181174436-181174936 1.8e-17 29_[+2]_39 chr5:10543711-10544211 2e-17 36_[-2]_32 chr6:27544050-27544550 6.4e-17 46_[+2]_22 chr5:181218376-181218876 1.8e-16 32_[-2]_36 chr16:75445725-75446225 4.3e-16 31_[-2]_37 chr19:36070135-36070635 4.3e-16 28_[+2]_40 chr10:8702990-8703490 1.1e-15 12_[-2]_56 chr1:150876802-150877302 1.5e-15 41_[-2]_27 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG width=32 seqs=17 chr12:124922496-12492299 ( 52) GGCCAGGCTGGTCTCGAACTCCTGACCTCAGG 1 chr10:23420805-23421305 ( 16) GGCCAGGCTGGTCTCGAACTCCTGACCTCATG 1 chr17:1258901-1259401 ( 61) GGCCAGGCTGGTCTCGAACTCCTGACCTCAAG 1 chr16:30598283-30598783 ( 32) GGTCAGGCTGGTCTCGAACTCCTGACCTCAGG 1 chr16:25055673-25056173 ( 29) GGCCAGGCTGGTCTCGAACCCCTGACCTCAGG 1 chr10:5853639-5854139 ( 49) GCCCAGGCTGGTCTCGAACTCCTGACCTCAGG 1 chr6:30907512-30908012 ( 14) GGCCAGGATGGTCTCGAACTCCTGACCTCGGG 1 chr19:39033019-39033519 ( 35) GGCCAGGCTGGTCTCGAACTTCTGACCTCAAG 1 chr5:181215948-181216448 ( 40) GGTCAGGCTGGTCTCGAACGCCTGACCTCAGG 1 chr5:181174436-181174936 ( 30) GGTTAGGCTGGTCTCGAACTCCTGACCTCATG 1 chr5:10543711-10544211 ( 37) GGCCAGGCTGGTCTCGAACCACTGACCTCAGG 1 chr6:27544050-27544550 ( 47) AGCCAGGATGGTCTCGATCTCCTGACCTCATG 1 chr5:181218376-181218876 ( 33) AGCCAGGATGGTCTCGATCTCCTGACCTCGTG 1 chr16:75445725-75446225 ( 32) GCCCAGGCTGGTCTTGAACTCCTGACCTTGTG 1 chr19:36070135-36070635 ( 29) GGCCTGGCTGGTCTCGAACTCCTGACCTTTAG 1 chr10:8702990-8703490 ( 13) GGCCAGGCTAGTATCGAACTCCTCACCTCGTG 1 chr1:150876802-150877302 ( 42) GGCCAGGCTGGTTTCGAACCCCTGGCCACAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 32 n= 41400 bayes= 8.60846 E= 1.3e-136 -96 -1073 170 -1073 -1073 -120 170 -1073 -1073 160 -1073 -37 -1073 179 -1073 -196 204 -1073 -1073 -196 -1073 -1073 188 -1073 -1073 -1073 188 -1073 -37 160 -1073 -1073 -1073 -1073 -1073 213 -196 -1073 179 -1073 -1073 -1073 188 -1073 -1073 -1073 -1073 213 -196 170 -1073 -196 -1073 -1073 -1073 213 -1073 179 -1073 -196 -1073 -1073 188 -1073 213 -1073 -1073 -1073 195 -1073 -1073 -96 -1073 188 -1073 -1073 -1073 -62 -220 174 -196 170 -1073 -196 -1073 188 -1073 -1073 -1073 -1073 -1073 213 -1073 -220 179 -1073 204 -1073 -220 -1073 -1073 188 -1073 -1073 -1073 188 -1073 -1073 -196 -1073 -1073 204 -1073 170 -1073 -96 163 -1073 -21 -196 -37 -1073 79 63 -1073 -1073 188 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 32 nsites= 17 E= 1.3e-136 0.117647 0.000000 0.882353 0.000000 0.000000 0.117647 0.882353 0.000000 0.000000 0.823529 0.000000 0.176471 0.000000 0.941176 0.000000 0.058824 0.941176 0.000000 0.000000 0.058824 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.176471 0.823529 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.058824 0.000000 0.941176 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.058824 0.882353 0.000000 0.058824 0.000000 0.000000 0.000000 1.000000 0.000000 0.941176 0.000000 0.058824 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.882353 0.000000 0.000000 0.117647 0.000000 1.000000 0.000000 0.000000 0.000000 0.176471 0.058824 0.764706 0.058824 0.882353 0.000000 0.058824 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.058824 0.941176 0.000000 0.941176 0.000000 0.058824 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.058824 0.000000 0.000000 0.941176 0.000000 0.882353 0.000000 0.117647 0.705882 0.000000 0.235294 0.058824 0.176471 0.000000 0.470588 0.352941 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCCAGGCTGGTCTCGAACTCCTGACCTCAKG MEME-2 regular expression -------------------------------------------------------------------------------- GGCCAGGCTGGTCTCGAACTCCTGACCTC[AG][GT]G -------------------------------------------------------------------------------- Time 1369.50 secs. ******************************************************************************** ******************************************************************************** MOTIF ATCCRCCYGCCTCGGCCTCCCA MEME-3 width = 22 sites = 25 llr = 543 E-value = 1.4e-089 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A 91::4:::2::::2:::::::8 pos.-specific C ::8827a6:9a:8:1aa:aa9: probability G 1:::31::8::::79::::::2 matrix T :92122:3:1:a2::::a::1: bits 2.1 * 1.9 * * *** * 1.7 ** * ** ***** 1.5 ** * *** ****** Relative 1.3 *** * **** ******** Entropy 1.1 **** * ***** ******** (31.3 bits) 0.9 **** ***************** 0.6 **** ***************** 0.4 **** ***************** 0.2 ********************** 0.0 ---------------------- Multilevel ATCCACCCGCCTCGGCCTCCCA consensus T GT T TA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr16:75445725-75446225 - 10 1.22e-13 TGACCTTGTG ATCCACCCGCCTCGGCCTCCCA AAGTGCTGG chr16:25055673-25056173 - 5 1.22e-13 ACCTCAGGTG ATCCACCCGCCTCGGCCTCCCA AAGT chr1:161764895-161765395 + 25 2.66e-13 tgacctcgtg atccgcccgcctcggcctccca aagtgctggg chr10:23420805-23421305 + 48 3.70e-13 tgacctcatg atccacctgcctcggcctccca aagtgctggg chr5:10543711-10544211 - 13 8.20e-13 ACCTCAGGTA ATCCACCCGCCTTGGCCTCCCA AAGTGCTAAG chr5:181215948-181216448 + 74 2.16e-12 acctcaggtg atccacccacctcggcctccca aagtg chr19:39033019-39033519 - 11 2.54e-12 ACCTCAAGCG ATCCGCCTGCCTTGGCCTCCCA AAGTGCTGGG chr1:146039400-146039900 - 56 2.97e-12 ACCTCAGGTG ATCCGCCCACCTCGGCCTCCCA AAGTACTGGG chr6:27544050-27544550 + 79 3.41e-12 tgacctcatg atccacccgccttagcctccca chr5:181174436-181174936 + 62 5.75e-12 tgacctcatg atccacccgtctcggcctccca aagtgctggg chr1:150876802-150877302 - 18 8.08e-12 GCCACAGGTG ATCCGGCCGCCTCGGCCTCCCA AAGTGCTGGG chr5:181218376-181218876 - 11 1.31e-11 TGACCTCGTG ATCCGCCAGCCTCGGCCTCCCA AAGTGCTGGG chr16:30598283-30598783 - 8 2.51e-11 ACCTCAGGTG ATCTGCCTGCCTTGGCCTCCCA AAGTGCT chr10:5853639-5854139 - 25 5.47e-11 ACCTCAGGTG ATCTACCCACCTTGGCCTCCCA AAGTGCTCGG chr19:36070135-36070635 + 63 5.99e-11 acctttagtg atccatccgtcttggcctccca CTGCGCCCGG chr18:49460605-49461105 - 66 9.37e-11 TGACCTCGTG ATCCGTCCACCTCGGCCTCCTA AAGTGCTGGG chr6:28790329-28790829 - 13 1.55e-10 AGTTCAAGCG ATTCTCCTGCCTCAGCCTCCCG AGTAGCTGGG chr22:37844459-37844959 + 15 1.55e-10 ccttgaagca attctcctgcctcagcctcccg agtagctggg chr3:169763010-169763510 - 1 3.10e-10 ACCTCAGGTG ATCCGCCCGCTTCTGCCTCCCA chr12:55829089-55829589 - 48 3.86e-10 GGTTCAAGCG ATTCTTCTGCCTCAGCCTCCCG AGTAGCTGGG chr6:28757402-28757902 + 17 6.25e-10 acctcaggtg atcgccccgcctcggccttcca aagtgctggg chr1:146038290-146038790 + 2 6.68e-10 a attctcctgcctcagcctcctg agtagctggg chr1:154182976-154183476 + 74 6.31e-09 CGGATGTGAC GTCCCTCTGCCGCGCCCTCCCA CCGCC chr6:30907512-30908012 + 47 7.23e-09 gacctcgggt gattcgccgcctcggcctccca aagtgctagg chr1:25998103-25998603 + 79 1.56e-08 TCCCGTGCGT AACCCTCCGCCTCACCCTCCTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:75445725-75446225 1.2e-13 9_[-3]_69 chr16:25055673-25056173 1.2e-13 4_[-3]_74 chr1:161764895-161765395 2.7e-13 24_[+3]_54 chr10:23420805-23421305 3.7e-13 47_[+3]_31 chr5:10543711-10544211 8.2e-13 12_[-3]_66 chr5:181215948-181216448 2.2e-12 73_[+3]_5 chr19:39033019-39033519 2.5e-12 10_[-3]_68 chr1:146039400-146039900 3e-12 55_[-3]_23 chr6:27544050-27544550 3.4e-12 78_[+3] chr5:181174436-181174936 5.8e-12 61_[+3]_17 chr1:150876802-150877302 8.1e-12 17_[-3]_61 chr5:181218376-181218876 1.3e-11 10_[-3]_68 chr16:30598283-30598783 2.5e-11 7_[-3]_71 chr10:5853639-5854139 5.5e-11 24_[-3]_54 chr19:36070135-36070635 6e-11 62_[+3]_16 chr18:49460605-49461105 9.4e-11 65_[-3]_13 chr6:28790329-28790829 1.5e-10 12_[-3]_66 chr22:37844459-37844959 1.5e-10 14_[+3]_64 chr3:169763010-169763510 3.1e-10 [-3]_78 chr12:55829089-55829589 3.9e-10 47_[-3]_31 chr6:28757402-28757902 6.2e-10 16_[+3]_62 chr1:146038290-146038790 6.7e-10 1_[+3]_77 chr1:154182976-154183476 6.3e-09 73_[+3]_5 chr6:30907512-30908012 7.2e-09 46_[+3]_32 chr1:25998103-25998603 1.6e-08 78_[+3] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATCCRCCYGCCTCGGCCTCCCA width=22 seqs=25 chr16:75445725-75446225 ( 10) ATCCACCCGCCTCGGCCTCCCA 1 chr16:25055673-25056173 ( 5) ATCCACCCGCCTCGGCCTCCCA 1 chr1:161764895-161765395 ( 25) ATCCGCCCGCCTCGGCCTCCCA 1 chr10:23420805-23421305 ( 48) ATCCACCTGCCTCGGCCTCCCA 1 chr5:10543711-10544211 ( 13) ATCCACCCGCCTTGGCCTCCCA 1 chr5:181215948-181216448 ( 74) ATCCACCCACCTCGGCCTCCCA 1 chr19:39033019-39033519 ( 11) ATCCGCCTGCCTTGGCCTCCCA 1 chr1:146039400-146039900 ( 56) ATCCGCCCACCTCGGCCTCCCA 1 chr6:27544050-27544550 ( 79) ATCCACCCGCCTTAGCCTCCCA 1 chr5:181174436-181174936 ( 62) ATCCACCCGTCTCGGCCTCCCA 1 chr1:150876802-150877302 ( 18) ATCCGGCCGCCTCGGCCTCCCA 1 chr5:181218376-181218876 ( 11) ATCCGCCAGCCTCGGCCTCCCA 1 chr16:30598283-30598783 ( 8) ATCTGCCTGCCTTGGCCTCCCA 1 chr10:5853639-5854139 ( 25) ATCTACCCACCTTGGCCTCCCA 1 chr19:36070135-36070635 ( 63) ATCCATCCGTCTTGGCCTCCCA 1 chr18:49460605-49461105 ( 66) ATCCGTCCACCTCGGCCTCCTA 1 chr6:28790329-28790829 ( 13) ATTCTCCTGCCTCAGCCTCCCG 1 chr22:37844459-37844959 ( 15) ATTCTCCTGCCTCAGCCTCCCG 1 chr3:169763010-169763510 ( 1) ATCCGCCCGCTTCTGCCTCCCA 1 chr12:55829089-55829589 ( 48) ATTCTTCTGCCTCAGCCTCCCG 1 chr6:28757402-28757902 ( 17) ATCGCCCCGCCTCGGCCTTCCA 1 chr1:146038290-146038790 ( 2) ATTCTCCTGCCTCAGCCTCCTG 1 chr1:154182976-154183476 ( 74) GTCCCTCTGCCGCGCCCTCCCA 1 chr6:30907512-30908012 ( 47) GATTCGCCGCCTCGGCCTCCCA 1 chr1:25998103-25998603 ( 79) AACCCTCCGCCTCACCCTCCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 8.78248 E= 1.4e-089 201 -1129 -176 -1129 -151 -1129 -1129 201 -1129 156 -1129 -19 -1129 163 -276 -93 65 -76 24 -52 -1129 141 -176 -19 -1129 188 -1129 -1129 -251 124 -1129 48 -52 -1129 163 -1129 -1129 176 -1129 -151 -1129 182 -1129 -251 -1129 -1129 -276 207 -1129 149 -1129 7 7 -1129 141 -251 -1129 -176 176 -1129 -1129 188 -1129 -1129 -1129 188 -1129 -1129 -1129 -1129 -1129 213 -1129 182 -1129 -251 -1129 188 -1129 -1129 -1129 170 -1129 -93 181 -276 -76 -1129 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 25 E= 1.4e-089 0.920000 0.000000 0.080000 0.000000 0.080000 0.000000 0.000000 0.920000 0.000000 0.800000 0.000000 0.200000 0.000000 0.840000 0.040000 0.120000 0.360000 0.160000 0.320000 0.160000 0.000000 0.720000 0.080000 0.200000 0.000000 1.000000 0.000000 0.000000 0.040000 0.640000 0.000000 0.320000 0.160000 0.000000 0.840000 0.000000 0.000000 0.920000 0.000000 0.080000 0.000000 0.960000 0.000000 0.040000 0.000000 0.000000 0.040000 0.960000 0.000000 0.760000 0.000000 0.240000 0.240000 0.000000 0.720000 0.040000 0.000000 0.080000 0.920000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.960000 0.000000 0.040000 0.000000 1.000000 0.000000 0.000000 0.000000 0.880000 0.000000 0.120000 0.800000 0.040000 0.160000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATCCRCCYGCCTCGGCCTCCCA MEME-3 regular expression -------------------------------------------------------------------------------- AT[CT]C[AG][CT]C[CT]GCCT[CT][GA]GCCTCCCA -------------------------------------------------------------------------------- Time 2005.23 secs. ******************************************************************************** ******************************************************************************** MOTIF RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 width = 31 sites = 22 llr = 541 E-value = 2.2e-082 ******************************************************************************** -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 3146955::4:::33:a11a6569251a69a pos.-specific C :::::35a94::6:6::91:::3:159:::: probability G 5151::::::634::::::::4::3:::::: matrix T 171311::1246:7:a::8:3::15:::4:: bits 2.1 * * * 1.9 ** * * * 1.7 * ** * * * 1.5 * ** ** * * * ** Relative 1.3 * ** * ***** * ***** Entropy 1.1 * *** * ****** * ****** (35.5 bits) 0.9 * ** *** ************ * ****** 0.6 ******** ************** ****** 0.4 ********* ************** ****** 0.2 ******************************* 0.0 ------------------------------- Multilevel GTGAAACCCAGTCTCTACTAAAAATACAAAA consensus A AT CA CTGGAA TGC GC T sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr10:8702990-8703490 + 51 5.50e-19 ggccaacata gtgaaaccccgtctctactaaaaatacaaaa attagccagg chr6:28752275-28752775 + 27 5.50e-19 ggccaacgtg gtgaaaccccgtctctactaaaaatacaaaa attagccagg chr19:45450372-45450872 + 17 5.29e-15 gactaacatg gcgaaaccccgtctctactaaaaatacaaaa attggtcgtg chr6:26313804-26314304 + 33 9.59e-15 ggccaacagg gtgacaccctgtctctactaaaaatacaaaa attagccggg chr16:25055673-25056173 + 68 2.88e-14 gccaacctga tgaaacccccgtctctactaaaaatacaaaa tt chr6:27544050-27544550 - 10 4.84e-14 GGCTAACATG ATGGAACCCCGTCTCTAATAAAAATACAAAA AAATTAGCC chr1:146038290-146038790 - 66 7.99e-14 CATA GTGAAACCTCGTCTCTACTAAAGATACAAAA ATTAGCTGGG chr18:22184439-22184939 - 28 1.29e-13 GGCCAACATG GTGAAACCCCGTCTCTACTAACTATACAAAA AAAAATTAGC chr6:28724796-28725296 + 17 2.87e-13 gccaacatag tgaaacccccgtctctactaaaaacacaaaa attagcaggg chr6:30488891-30489391 - 50 2.87e-13 GACCAATATG GAGAAACCCTGTCTCTACTAAAAGTCCAAAA AATTAGCCGG chr1:237151958-237152458 - 36 1.95e-12 AATGTGGCAC ATATACACCATGGAATACTATGCAGCCATAA AAAGGAATGA chr1:203314359-203314859 + 13 1.95e-12 aatgtggcac atatacaccatggaatactatgcagccataa aaaaggatga chr16:75445725-75446225 + 69 2.14e-12 tgggcaagat ggtgaaacctatctctactaaaaatacaaaa a chr16:30598283-30598783 + 70 6.26e-12 gaccaacatg gtgaaaccctgtctctacaaaaatactaaaa chr1:231728927-231729427 - 54 1.54e-11 AATGAGGCAC ATATACACCATGGAATACTACGCAGCCATAA AAAAGGTTGA chr10:68719969-68720469 + 28 1.80e-11 aatgtggcac atatacaccatggaataccatgcagccataa aaaaggttga chr19:50134119-50134619 + 26 4.13e-11 ggccaacatg gtgaaacactgtctctacaaaaatacaaaaa ttagctgggt chr15:69146685-69147185 - 28 4.44e-11 AATGTGACAC ATATACACCATGGAATACTATGCAACCATCA AAAAGGATGA chr19:33312748-33313248 + 20 2.50e-10 aatgtggtac gtatataccgtggaatactatgcagccatga aaaagaatga chr6:2028572-2029072 - 37 7.16e-10 ATAGTCGTTA GTATTTACTAGCCTCTATTATGAACACATAA ATCATTTCAT chr6:16628560-16629060 - 47 8.44e-10 AAATGTGGTA CATATTACCATGGAATACTATGCAGCCATAA AAAAGGAATG chr3:156161110-156161610 - 45 5.32e-09 AAAAGGGGTC ATTAAAACCATTGTGAAACAAGAAAAATAAA CATGTGGTAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:8702990-8703490 5.5e-19 50_[+4]_19 chr6:28752275-28752775 5.5e-19 26_[+4]_43 chr19:45450372-45450872 5.3e-15 16_[+4]_53 chr6:26313804-26314304 9.6e-15 32_[+4]_37 chr16:25055673-25056173 2.9e-14 67_[+4]_2 chr6:27544050-27544550 4.8e-14 9_[-4]_60 chr1:146038290-146038790 8e-14 65_[-4]_4 chr18:22184439-22184939 1.3e-13 27_[-4]_42 chr6:28724796-28725296 2.9e-13 16_[+4]_53 chr6:30488891-30489391 2.9e-13 49_[-4]_20 chr1:237151958-237152458 2e-12 35_[-4]_34 chr1:203314359-203314859 2e-12 12_[+4]_57 chr16:75445725-75446225 2.1e-12 68_[+4]_1 chr16:30598283-30598783 6.3e-12 69_[+4] chr1:231728927-231729427 1.5e-11 53_[-4]_16 chr10:68719969-68720469 1.8e-11 27_[+4]_42 chr19:50134119-50134619 4.1e-11 25_[+4]_44 chr15:69146685-69147185 4.4e-11 27_[-4]_42 chr19:33312748-33313248 2.5e-10 19_[+4]_50 chr6:2028572-2029072 7.2e-10 36_[-4]_33 chr6:16628560-16629060 8.4e-10 46_[-4]_23 chr3:156161110-156161610 5.3e-09 44_[-4]_25 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA width=31 seqs=22 chr10:8702990-8703490 ( 51) GTGAAACCCCGTCTCTACTAAAAATACAAAA 1 chr6:28752275-28752775 ( 27) GTGAAACCCCGTCTCTACTAAAAATACAAAA 1 chr19:45450372-45450872 ( 17) GCGAAACCCCGTCTCTACTAAAAATACAAAA 1 chr6:26313804-26314304 ( 33) GTGACACCCTGTCTCTACTAAAAATACAAAA 1 chr16:25055673-25056173 ( 68) TGAAACCCCCGTCTCTACTAAAAATACAAAA 1 chr6:27544050-27544550 ( 10) ATGGAACCCCGTCTCTAATAAAAATACAAAA 1 chr1:146038290-146038790 ( 66) GTGAAACCTCGTCTCTACTAAAGATACAAAA 1 chr18:22184439-22184939 ( 28) GTGAAACCCCGTCTCTACTAACTATACAAAA 1 chr6:28724796-28725296 ( 17) TGAAACCCCCGTCTCTACTAAAAACACAAAA 1 chr6:30488891-30489391 ( 50) GAGAAACCCTGTCTCTACTAAAAGTCCAAAA 1 chr1:237151958-237152458 ( 36) ATATACACCATGGAATACTATGCAGCCATAA 1 chr1:203314359-203314859 ( 13) ATATACACCATGGAATACTATGCAGCCATAA 1 chr16:75445725-75446225 ( 69) GGTGAAACCTATCTCTACTAAAAATACAAAA 1 chr16:30598283-30598783 ( 70) GTGAAACCCTGTCTCTACAAAAATACTAAAA 1 chr1:231728927-231729427 ( 54) ATATACACCATGGAATACTACGCAGCCATAA 1 chr10:68719969-68720469 ( 28) ATATACACCATGGAATACCATGCAGCCATAA 1 chr19:50134119-50134619 ( 26) GTGAAACACTGTCTCTACAAAAATACAAAAA 1 chr15:69146685-69147185 ( 28) ATATACACCATGGAATACTATGCAACCATCA 1 chr19:33312748-33313248 ( 20) GTATATACCGTGGAATACTATGCAGCCATGA 1 chr6:2028572-2029072 ( 37) GTATTTACTAGCCTCTATTATGAACACATAA 1 chr6:16628560-16629060 ( 47) CATATTACCATGGAATACTATGCAGCCATAA 1 chr3:156161110-156161610 ( 45) ATTAAAACCATTGTGAAACAAGAAAAATAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 10.4502 E= 2.2e-082 48 -257 101 -133 -133 -257 -99 167 84 -1110 74 -75 137 -1110 -158 48 192 -257 -1110 -133 125 23 -1110 -75 99 101 -1110 -1110 -233 181 -1110 -1110 -1110 174 -1110 -133 67 42 -257 -1 -233 -1110 112 67 -1110 -257 23 148 -1110 123 42 -1110 48 -1110 -1110 158 48 123 -257 -1110 -233 -1110 -1110 206 213 -1110 -1110 -1110 -133 167 -1110 -233 -133 -158 -1110 184 213 -1110 -1110 -1110 148 -257 -1110 48 125 -257 59 -1110 137 23 -257 -233 192 -1110 -257 -133 -33 -158 1 99 125 74 -1110 -1110 -133 167 -1110 -233 206 -1110 -1110 -233 148 -1110 -1110 67 199 -257 -257 -1110 213 -1110 -1110 -1110 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 22 E= 2.2e-082 0.318182 0.045455 0.545455 0.090909 0.090909 0.045455 0.136364 0.727273 0.409091 0.000000 0.454545 0.136364 0.590909 0.000000 0.090909 0.318182 0.863636 0.045455 0.000000 0.090909 0.545455 0.318182 0.000000 0.136364 0.454545 0.545455 0.000000 0.000000 0.045455 0.954545 0.000000 0.000000 0.000000 0.909091 0.000000 0.090909 0.363636 0.363636 0.045455 0.227273 0.045455 0.000000 0.590909 0.363636 0.000000 0.045455 0.318182 0.636364 0.000000 0.636364 0.363636 0.000000 0.318182 0.000000 0.000000 0.681818 0.318182 0.636364 0.045455 0.000000 0.045455 0.000000 0.000000 0.954545 1.000000 0.000000 0.000000 0.000000 0.090909 0.863636 0.000000 0.045455 0.090909 0.090909 0.000000 0.818182 1.000000 0.000000 0.000000 0.000000 0.636364 0.045455 0.000000 0.318182 0.545455 0.045455 0.409091 0.000000 0.590909 0.318182 0.045455 0.045455 0.863636 0.000000 0.045455 0.090909 0.181818 0.090909 0.272727 0.454545 0.545455 0.454545 0.000000 0.000000 0.090909 0.863636 0.000000 0.045455 0.954545 0.000000 0.000000 0.045455 0.636364 0.000000 0.000000 0.363636 0.909091 0.045455 0.045455 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RTRWAMMCCHKKSTMTACTAWRMAKMCAWAA MEME-4 regular expression -------------------------------------------------------------------------------- [GA]T[GA][AT]A[AC][CA]CC[ACT][GT][TG][CG][TA][CA]TACTA[AT][AG][AC]A[TG][AC]CA[AT]AA -------------------------------------------------------------------------------- Time 2634.03 secs. ******************************************************************************** ******************************************************************************** MOTIF ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 width = 31 sites = 15 llr = 479 E-value = 1.1e-085 ******************************************************************************** -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 Description -------------------------------------------------------------------------------- Simplified A a5:52::1::9::a:911:2::51:1a::5: pos.-specific C :::::91:::11::9::19:314:99:99:a probability G :5518::9aa:::::199:8:9:9::::15: matrix T ::55:19::::9a:1:::1:7:1:1::11:: bits 2.1 * ** * 1.9 * ** ** * * 1.7 * * *** ** * * * 1.5 * ** ********* * *** * Relative 1.3 * ****************** ****** * Entropy 1.1 *** ****************** ******** (46.1 bits) 0.9 ********************** ******** 0.6 ******************************* 0.4 ******************************* 0.2 ******************************* 0.0 ------------------------------- Multilevel AGTAGCTGGGATTACAGGCGTGAGCCACCAC consensus AGTA AC C G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr18:49460605-49461105 - 35 9.56e-18 CGGCCTCCTA AAGTGCTGGGATTACAGGCGTGAGCCACCGC GCACGGCTGT chr1:161764895-161765395 + 47 9.56e-18 cggcctccca aagtgctgggattacaggcgtgagccaccgc gcccggccTT chr1:146039400-146039900 - 25 5.21e-17 CGGCCTCCCA AAGTACTGGGATTACAGGCGTGAGCCACCGC GCCCGGCCCA chr19:44259548-44260048 + 11 2.38e-16 tggcctccca aagtgctgggattacaggcgtgagccactgc acctggccCC chr6:28757402-28757902 + 39 2.38e-16 cggccttcca aagtgctgggattacagacgtgagccaccgc gcccggACCT chr22:37844459-37844959 + 37 3.65e-16 cagcctcccg agtagctgggactacaggcgcgcgccaccac gcccagctaa chr1:146038290-146038790 + 24 7.28e-16 cagcctcctg agtagctgggattacaggcgcccgccaccac gcccagctaa chr6:30907512-30908012 + 69 1.74e-15 cggcctccca aagtgctaggattacaggcgtgagtcaccgc g chr12:55829089-55829589 - 17 2.13e-15 CAGCCTCCCG AGTAGCTGGGACTACAGGTGCGCGCCACCAC GCCTGGCGAA chr10:23420805-23421305 + 70 6.74e-15 cggcctccca aagtgctgggcttacgggcgtgagccaccgc chr19:50134119-50134619 - 67 1.23e-14 CCA AGTGACTGGGATTATAGGCGTGTGCCACCAC ACCCAGCTAA chr6:28752275-28752775 - 69 1.66e-14 G AGTAGCTGGGATTACAAGCATGTGCAACCAC GCCTGGCTAA chr6:30488891-30489391 + 8 3.93e-14 cctccca agtagccaggattacagccatgcgccaccac gccggctaat chr6:28724796-28725296 - 59 4.16e-14 CAGCCTACCG AGTAACTGGGATTACAGGCATGCACCATGAC ACCCTGCTAA chr19:45450372-45450872 - 55 5.01e-14 CAGCCTCCAC AGTAGTTGGGATTACAGGTGCGCACCATCAC GACCAATTTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr18:49460605-49461105 9.6e-18 34_[-5]_35 chr1:161764895-161765395 9.6e-18 46_[+5]_23 chr1:146039400-146039900 5.2e-17 24_[-5]_45 chr19:44259548-44260048 2.4e-16 10_[+5]_59 chr6:28757402-28757902 2.4e-16 38_[+5]_31 chr22:37844459-37844959 3.7e-16 36_[+5]_33 chr1:146038290-146038790 7.3e-16 23_[+5]_46 chr6:30907512-30908012 1.7e-15 68_[+5]_1 chr12:55829089-55829589 2.1e-15 16_[-5]_53 chr10:23420805-23421305 6.7e-15 69_[+5] chr19:50134119-50134619 1.2e-14 66_[-5]_3 chr6:28752275-28752775 1.7e-14 68_[-5]_1 chr6:30488891-30489391 3.9e-14 7_[+5]_62 chr6:28724796-28725296 4.2e-14 58_[-5]_11 chr19:45450372-45450872 5e-14 54_[-5]_15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ARKWGCTGGGATTACAGGCGTGMGCCACCRC width=31 seqs=15 chr18:49460605-49461105 ( 35) AAGTGCTGGGATTACAGGCGTGAGCCACCGC 1 chr1:161764895-161765395 ( 47) AAGTGCTGGGATTACAGGCGTGAGCCACCGC 1 chr1:146039400-146039900 ( 25) AAGTACTGGGATTACAGGCGTGAGCCACCGC 1 chr19:44259548-44260048 ( 11) AAGTGCTGGGATTACAGGCGTGAGCCACTGC 1 chr6:28757402-28757902 ( 39) AAGTGCTGGGATTACAGACGTGAGCCACCGC 1 chr22:37844459-37844959 ( 37) AGTAGCTGGGACTACAGGCGCGCGCCACCAC 1 chr1:146038290-146038790 ( 24) AGTAGCTGGGATTACAGGCGCCCGCCACCAC 1 chr6:30907512-30908012 ( 69) AAGTGCTAGGATTACAGGCGTGAGTCACCGC 1 chr12:55829089-55829589 ( 17) AGTAGCTGGGACTACAGGTGCGCGCCACCAC 1 chr10:23420805-23421305 ( 70) AAGTGCTGGGCTTACGGGCGTGAGCCACCGC 1 chr19:50134119-50134619 ( 67) AGTGACTGGGATTATAGGCGTGTGCCACCAC 1 chr6:28752275-28752775 ( 69) AGTAGCTGGGATTACAAGCATGTGCAACCAC 1 chr6:30488891-30489391 ( 8) AGTAGCCAGGATTACAGCCATGCGCCACCAC 1 chr6:28724796-28725296 ( 59) AGTAACTGGGATTACAGGCATGCACCATGAC 1 chr19:45450372-45450872 ( 55) AGTAGTTGGGATTACAGGTGCGCACCATCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 12.1251 E= 1.1e-085 213 -1055 -1055 -1055 103 -1055 97 -1055 -1055 -1055 78 122 103 -1055 -202 103 -19 -1055 156 -1055 -1055 178 -1055 -178 -1055 -202 -1055 203 -78 -1055 167 -1055 -1055 -1055 188 -1055 -1055 -1055 188 -1055 203 -202 -1055 -1055 -1055 -102 -1055 192 -1055 -1055 -1055 213 213 -1055 -1055 -1055 -1055 178 -1055 -178 203 -1055 -202 -1055 -178 -1055 178 -1055 -178 -202 167 -1055 -1055 167 -1055 -78 -19 -1055 156 -1055 -1055 -2 -1055 168 -1055 -202 178 -1055 103 56 -1055 -78 -78 -1055 167 -1055 -1055 178 -1055 -178 -178 178 -1055 -1055 213 -1055 -1055 -1055 -1055 167 -1055 -78 -1055 167 -202 -178 122 -1055 78 -1055 -1055 188 -1055 -1055 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 15 E= 1.1e-085 1.000000 0.000000 0.000000 0.000000 0.466667 0.000000 0.533333 0.000000 0.000000 0.000000 0.466667 0.533333 0.466667 0.000000 0.066667 0.466667 0.200000 0.000000 0.800000 0.000000 0.000000 0.933333 0.000000 0.066667 0.000000 0.066667 0.000000 0.933333 0.133333 0.000000 0.866667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.933333 0.066667 0.000000 0.000000 0.000000 0.133333 0.000000 0.866667 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.933333 0.000000 0.066667 0.933333 0.000000 0.066667 0.000000 0.066667 0.000000 0.933333 0.000000 0.066667 0.066667 0.866667 0.000000 0.000000 0.866667 0.000000 0.133333 0.200000 0.000000 0.800000 0.000000 0.000000 0.266667 0.000000 0.733333 0.000000 0.066667 0.933333 0.000000 0.466667 0.400000 0.000000 0.133333 0.133333 0.000000 0.866667 0.000000 0.000000 0.933333 0.000000 0.066667 0.066667 0.933333 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.866667 0.000000 0.133333 0.000000 0.866667 0.066667 0.066667 0.533333 0.000000 0.466667 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARKWGCTGGGATTACAGGCGTGMGCCACCRC MEME-5 regular expression -------------------------------------------------------------------------------- A[GA][TG][AT][GA]CTGGGATTACAGGC[GA][TC]G[AC]GCCACC[AG]C -------------------------------------------------------------------------------- Time 3277.32 secs. ******************************************************************************** ******************************************************************************** MOTIF KGCHTBCTGGGADWTGTAGTYY MEME-6 width = 22 sites = 24 llr = 440 E-value = 1.8e-050 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 Description -------------------------------------------------------------------------------- Simplified A 2:23:111:::a33:::9:::: pos.-specific C ::63138::::::12:::::56 probability G 59:1:3::a9a:41:a:1a::: matrix T 31239318:1::358:a::a54 bits 2.1 * 1.9 * ** ** ** 1.7 * ** ***** 1.5 * **** ***** Relative 1.3 * * ***** ****** Entropy 1.1 * * ***** ****** (26.5 bits) 0.9 * * ****** ******** 0.6 * * ****** ******** 0.4 *** * ****** ********* 0.2 ***** **************** 0.0 ---------------------- Multilevel GGCATCCTGGGAGTTGTAGTTC consensus T C T TAC CT sequence A T G A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr19:48644710-48645210 - 15 2.88e-12 GTAGCACTGG GGCCTGCTGGGAGTTGTAGTTC CATCTACAGT chr16:2047673-2048173 - 43 2.23e-11 CCGCCTTGGG AGCTTGCTGGGAGTTGTAGTTC TGTGCCGCCC chr19:44071882-44072382 + 5 5.29e-11 CCGG GGAATTCTGGGAAATGTAGTTC ACACGCTGCG chr19:19776285-19776785 - 21 6.09e-11 CGCCGCGCCT GGTATGCTGGGAGTTGTAGTCT CTTTACTGCT chr19:35748176-35748676 - 10 1.66e-10 TCTACCCCCT AGCTTCCTGGGAGGTGTAGTTC CAGCTTCCC chr12:53727423-53727923 + 1 3.04e-10 . GGCATCCTGGGAGGCGTAGTTC TCACTCCTAT chr7:93232066-93232566 - 41 4.27e-10 TCTTTCCCTG GGCCTGCTGGGAACTGTAGTCT TCTGGACGCC chr14:80941611-80942111 - 45 4.27e-10 CCAGCTATAT GGCATCCTGGGATTTGCAGTTC CTTTTCGGGA chr19:44164671-44165171 + 15 6.63e-10 CCCCAACTCC AGCATTCTGTGATATGTAGTCC GGAGTTCCGT chr7:77122175-77122675 - 54 9.09e-10 CCCTGCGCAT TGCCTCCTGGGATATGTGGTTT CTAAGAGGCG chr7:102748618-102749118 + 67 1.23e-09 CCCTGCGCAT TGCCTCCTGGGAAATGTGGTTT CTAAGAGGCA chr1:230978766-230979266 - 36 1.35e-09 GCGCCGCGCG GGCTTATTGGGATTCGTAGTCC CGGCACCGGC chr10:102132686-10213318 + 66 1.35e-09 CTCGCCGCAC GGCTCTCTGGGATTCGTAGTCT TGCAGTGTCA chr7:5822859-5823359 + 69 1.49e-09 GGCGTCGTGG GGGGTTCTGGGAGTTGTAGTCC CTGGGGGAGC chr19:46850667-46851167 + 30 1.49e-09 TCTCGCGCAC AGACCCCTGGGAGTTGTAGTTT CACCAAAGGG chr1:45499908-45500408 - 67 2.57e-09 CTATGCGCGA TGCATCTTGGGATGCGTAGTTC GTTTCCTCCT chr2:75646495-75646995 + 73 2.81e-09 CTCGTCGCAC TGATTACTGGGAGCTGTAGTCT TGACGT chr1:36224038-36224538 + 66 3.96e-09 ACGCTCGCCT TGTCTTTTGGGAAACGTAGTTC TGATGGCAGC chr14:44961891-44962391 - 6 5.08e-09 CTTGCCGTGA TGAATGCTGGGTTATGTAGTCC ACGTC chr19:36214708-36215208 + 57 5.96e-09 CGACCAGTAA AGCCTCAAGGGAAATGTAGTCC AAGGCCTGAG chr11:61792430-61792930 + 31 1.54e-08 CGGCGCAAGT GGCATTGAGGGACTTGTAGTCC TGCGATTTCG chr5:146182503-146183003 - 28 3.96e-08 GATAACCCGT TTTTCTCTGGGAATTGTAGTCA GTTAGCGCCT chr14:61331985-61332485 - 7 7.25e-08 TAAAATGTCT GTCCTACAGTGATTTGTAGTAT TTGTCA chr19:16495951-16496451 - 56 1.03e-07 ATAATCGCGA GTTGTGACGGGAGTTGTAGTTT CGGGACGCGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:48644710-48645210 2.9e-12 14_[-6]_64 chr16:2047673-2048173 2.2e-11 42_[-6]_36 chr19:44071882-44072382 5.3e-11 4_[+6]_74 chr19:19776285-19776785 6.1e-11 20_[-6]_58 chr19:35748176-35748676 1.7e-10 9_[-6]_69 chr12:53727423-53727923 3e-10 [+6]_78 chr7:93232066-93232566 4.3e-10 40_[-6]_38 chr14:80941611-80942111 4.3e-10 44_[-6]_34 chr19:44164671-44165171 6.6e-10 14_[+6]_64 chr7:77122175-77122675 9.1e-10 53_[-6]_25 chr7:102748618-102749118 1.2e-09 66_[+6]_12 chr1:230978766-230979266 1.4e-09 35_[-6]_43 chr10:102132686-10213318 1.4e-09 65_[+6]_13 chr7:5822859-5823359 1.5e-09 68_[+6]_10 chr19:46850667-46851167 1.5e-09 29_[+6]_49 chr1:45499908-45500408 2.6e-09 66_[-6]_12 chr2:75646495-75646995 2.8e-09 72_[+6]_6 chr1:36224038-36224538 4e-09 65_[+6]_13 chr14:44961891-44962391 5.1e-09 5_[-6]_73 chr19:36214708-36215208 6e-09 56_[+6]_22 chr11:61792430-61792930 1.5e-08 30_[+6]_48 chr5:146182503-146183003 4e-08 27_[-6]_51 chr14:61331985-61332485 7.2e-08 6_[-6]_72 chr19:16495951-16496451 1e-07 55_[-6]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGCHTBCTGGGADWTGTAGTYY width=22 seqs=24 chr19:48644710-48645210 ( 15) GGCCTGCTGGGAGTTGTAGTTC 1 chr16:2047673-2048173 ( 43) AGCTTGCTGGGAGTTGTAGTTC 1 chr19:44071882-44072382 ( 5) GGAATTCTGGGAAATGTAGTTC 1 chr19:19776285-19776785 ( 21) GGTATGCTGGGAGTTGTAGTCT 1 chr19:35748176-35748676 ( 10) AGCTTCCTGGGAGGTGTAGTTC 1 chr12:53727423-53727923 ( 1) GGCATCCTGGGAGGCGTAGTTC 1 chr7:93232066-93232566 ( 41) GGCCTGCTGGGAACTGTAGTCT 1 chr14:80941611-80942111 ( 45) GGCATCCTGGGATTTGCAGTTC 1 chr19:44164671-44165171 ( 15) AGCATTCTGTGATATGTAGTCC 1 chr7:77122175-77122675 ( 54) TGCCTCCTGGGATATGTGGTTT 1 chr7:102748618-102749118 ( 67) TGCCTCCTGGGAAATGTGGTTT 1 chr1:230978766-230979266 ( 36) GGCTTATTGGGATTCGTAGTCC 1 chr10:102132686-10213318 ( 66) GGCTCTCTGGGATTCGTAGTCT 1 chr7:5822859-5823359 ( 69) GGGGTTCTGGGAGTTGTAGTCC 1 chr19:46850667-46851167 ( 30) AGACCCCTGGGAGTTGTAGTTT 1 chr1:45499908-45500408 ( 67) TGCATCTTGGGATGCGTAGTTC 1 chr2:75646495-75646995 ( 73) TGATTACTGGGAGCTGTAGTCT 1 chr1:36224038-36224538 ( 66) TGTCTTTTGGGAAACGTAGTTC 1 chr14:44961891-44962391 ( 6) TGAATGCTGGGTTATGTAGTCC 1 chr19:36214708-36215208 ( 57) AGCCTCAAGGGAAATGTAGTCC 1 chr11:61792430-61792930 ( 31) GGCATTGAGGGACTTGTAGTCC 1 chr5:146182503-146183003 ( 28) TTTTCTCTGGGAATTGTAGTCA 1 chr14:61331985-61332485 ( 7) GTCCTACAGTGATTTGTAGTAT 1 chr19:16495951-16496451 ( 56) GTTGTGACGGGAGTTGTAGTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 10.6057 E= 1.8e-050 -13 -1123 88 35 -1123 -1123 169 -87 -46 120 -270 -46 54 30 -170 13 -1123 -112 -1123 194 -87 30 -12 35 -146 147 -270 -87 -87 -270 -1123 187 -1123 -1123 188 -1123 -1123 -1123 176 -146 -1123 -1123 188 -1123 207 -1123 -1123 -245 13 -270 47 54 35 -170 -112 113 -1123 -38 -1123 179 -1123 -1123 188 -1123 -1123 -270 -1123 207 200 -1123 -170 -1123 -1123 -1123 188 -1123 -1123 -1123 -1123 213 -245 76 -1123 113 -245 110 -1123 71 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 24 E= 1.8e-050 0.208333 0.000000 0.500000 0.291667 0.000000 0.000000 0.875000 0.125000 0.166667 0.625000 0.041667 0.166667 0.333333 0.333333 0.083333 0.250000 0.000000 0.125000 0.000000 0.875000 0.125000 0.333333 0.250000 0.291667 0.083333 0.750000 0.041667 0.125000 0.125000 0.041667 0.000000 0.833333 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.916667 0.083333 0.000000 0.000000 1.000000 0.000000 0.958333 0.000000 0.000000 0.041667 0.250000 0.041667 0.375000 0.333333 0.291667 0.083333 0.125000 0.500000 0.000000 0.208333 0.000000 0.791667 0.000000 0.000000 1.000000 0.000000 0.000000 0.041667 0.000000 0.958333 0.916667 0.000000 0.083333 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.041667 0.458333 0.000000 0.500000 0.041667 0.583333 0.000000 0.375000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCHTBCTGGGADWTGTAGTYY MEME-6 regular expression -------------------------------------------------------------------------------- [GTA]GC[ACT]T[CTG]CTGGGA[GTA][TA][TC]GTAGT[TC][CT] -------------------------------------------------------------------------------- Time 3952.73 secs. ******************************************************************************** ******************************************************************************** MOTIF WGAGRGAGDGARAGAR MEME-7 width = 16 sites = 30 llr = 398 E-value = 2.0e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 Description -------------------------------------------------------------------------------- Simplified A 516:5:814:a37285 pos.-specific C :::::1::1::::::: probability G 193a49:93a:71824 matrix T 3:1:1:2:2:::3::1 bits 2.1 * 1.9 * ** 1.7 * ** 1.5 * ** ** * Relative 1.3 * * *** ** * Entropy 1.1 * * *** *** ** (19.2 bits) 0.9 *** *** ****** 0.6 ******** ******* 0.4 ******** ******* 0.2 **************** 0.0 ---------------- Multilevel AGAGAGAGAGAGAGAA consensus T G G G ATA G sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr17:48728638-48729138 - 15 1.86e-10 AGAAAGAGAG AGAGAGAGAGAGAGAA TAAGCTGGGG chr1:155244578-155245078 + 73 8.12e-10 agagcgagcg agagagagagagagag agagaggagC chr1:234723902-234724402 + 8 8.12e-10 gtgtgtg agagagagagagagag agaaatggag chr1:226711146-226711646 + 62 8.12e-10 GTTTTGAAag agagagagagagagag agagagagag chr10:101442053-10144255 - 11 8.12e-10 AGAGACAGAG AGAGAGAGAGAGAGAG ATTCTAATTC chr1:226944558-226945058 + 12 2.34e-09 agagtgagag agagagagtgagagag agagagTGTG chr11:93783967-93784467 - 2 1.61e-08 CGTGGCCGGC AGAGGGAGGGAAAGAG C chr7:70092329-70092829 + 70 1.08e-07 CATGAGCTTA AGAGAGTGTGAGTGAA AGCTGATATT chr1:220527612-220528112 - 84 1.08e-07 T TGAGGGTGAGAGAGAG CTGATGTGAA chr5:57042475-57042975 - 1 1.50e-07 TACTGGCTGT TAGGAGAGAGAGAGAA chr9:136579563-136580063 - 77 1.91e-07 TGAGGGAA TGAGTGAGTGAGTGAA TGAGCAAGTG chr16:1308127-1308627 + 27 3.55e-07 CGGGAATGAG TGAGAGTGAGAAtgag tgagtgaggg chr1:179882537-179883037 + 53 3.55e-07 ATTCTGCGAA AGAGGAAGTGAGAGAA AGCGCGTACT chr5:53478397-53478897 + 25 4.25e-07 GAGTCTGGGT AGAGGGAGGGAAGGAG AGAAGAGGGG chr14:36835046-36835546 - 74 4.64e-07 AAATGTGGGC AGAGAGAGGGAGTAAT TTGTTAATGT chr12:54359085-54359585 + 73 6.15e-07 TCTGCCTGTA AGAGACAGCGAAAGAG AGAGAGCGTG chr17:58417458-58417958 - 54 6.15e-07 CTGAGGGAGG GGGGAGAGCGAAAGAA CGGGTCTGGT chr5:37371026-37371526 + 61 6.68e-07 TTTagggaag ggagggagggaaagga agggaaggat chr19:4815136-4815636 - 76 8.58e-07 ATGAGTGAA TGAGTGAGTGAATAAA TGAACGAGTC chr22:39520174-39520674 + 64 8.58e-07 TTGGGGCGTC AAagggagggagggaa gggagcgggc chr10:74826043-74826543 + 42 1.01e-06 GCGCGGTATC TAGGAGAGAGAAAAAG GGCTGGACCA chr19:49580397-49580897 - 85 1.09e-06 . AGAGAGAAAGAGAAGA GAGGACTTGA chr12:50111901-50112401 + 12 1.27e-06 TAACCCGGCA GGTGGGAGGGAGAAAG TTGCTTTCTG chr3:15427348-15427848 - 48 1.27e-06 CTCCTCTGCG TGGGGGTGAGAGAGGA ATCTGAGGAG chr1:169893813-169894313 - 75 1.37e-06 ACTAGACCAC TGGGGCAGTGAGTGAA ACTCGGTATC chr5:150449660-150450160 + 30 1.69e-06 TTATTACTTA AGGGAGAGCGAAAAGA GGTAGAGGGC chr3:72887609-72888109 + 52 2.08e-06 GTGGATGGCA TGGGTGTGTGAGTGAA TGGGGAAGTA chr8:71355221-71355721 + 24 2.22e-06 CCTATAGTCT AGTGACAGGGAATGAG ATAGTCCTGA chr1:66924920-66925420 - 57 5.00e-06 TGCCGTGGGG GAGGGGAAGGAGAGAA AGGGGACTGA chr8:74350128-74350628 + 74 6.10e-06 TGCGGGGCAG TGTGGGAGGGAGAAGT CCAGGGCGGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:48728638-48729138 1.9e-10 14_[-7]_70 chr1:155244578-155245078 8.1e-10 72_[+7]_12 chr1:234723902-234724402 8.1e-10 7_[+7]_77 chr1:226711146-226711646 8.1e-10 61_[+7]_23 chr10:101442053-10144255 8.1e-10 10_[-7]_74 chr1:226944558-226945058 2.3e-09 11_[+7]_73 chr11:93783967-93784467 1.6e-08 1_[-7]_83 chr7:70092329-70092829 1.1e-07 69_[+7]_15 chr1:220527612-220528112 1.1e-07 83_[-7]_1 chr5:57042475-57042975 1.5e-07 [-7]_84 chr9:136579563-136580063 1.9e-07 76_[-7]_8 chr16:1308127-1308627 3.5e-07 26_[+7]_58 chr1:179882537-179883037 3.5e-07 52_[+7]_32 chr5:53478397-53478897 4.2e-07 24_[+7]_60 chr14:36835046-36835546 4.6e-07 73_[-7]_11 chr12:54359085-54359585 6.1e-07 72_[+7]_12 chr17:58417458-58417958 6.1e-07 53_[-7]_31 chr5:37371026-37371526 6.7e-07 60_[+7]_24 chr19:4815136-4815636 8.6e-07 75_[-7]_9 chr22:39520174-39520674 8.6e-07 63_[+7]_21 chr10:74826043-74826543 1e-06 41_[+7]_43 chr19:49580397-49580897 1.1e-06 84_[-7] chr12:50111901-50112401 1.3e-06 11_[+7]_73 chr3:15427348-15427848 1.3e-06 47_[-7]_37 chr1:169893813-169894313 1.4e-06 74_[-7]_10 chr5:150449660-150450160 1.7e-06 29_[+7]_55 chr3:72887609-72888109 2.1e-06 51_[+7]_33 chr8:71355221-71355721 2.2e-06 23_[+7]_61 chr1:66924920-66925420 5e-06 56_[-7]_28 chr8:74350128-74350628 6.1e-06 73_[+7]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGAGRGAGDGARAGAR width=16 seqs=30 chr17:48728638-48729138 ( 15) AGAGAGAGAGAGAGAA 1 chr1:155244578-155245078 ( 73) AGAGAGAGAGAGAGAG 1 chr1:234723902-234724402 ( 8) AGAGAGAGAGAGAGAG 1 chr1:226711146-226711646 ( 62) AGAGAGAGAGAGAGAG 1 chr10:101442053-10144255 ( 11) AGAGAGAGAGAGAGAG 1 chr1:226944558-226945058 ( 12) AGAGAGAGTGAGAGAG 1 chr11:93783967-93784467 ( 2) AGAGGGAGGGAAAGAG 1 chr7:70092329-70092829 ( 70) AGAGAGTGTGAGTGAA 1 chr1:220527612-220528112 ( 84) TGAGGGTGAGAGAGAG 1 chr5:57042475-57042975 ( 1) TAGGAGAGAGAGAGAA 1 chr9:136579563-136580063 ( 77) TGAGTGAGTGAGTGAA 1 chr16:1308127-1308627 ( 27) TGAGAGTGAGAATGAG 1 chr1:179882537-179883037 ( 53) AGAGGAAGTGAGAGAA 1 chr5:53478397-53478897 ( 25) AGAGGGAGGGAAGGAG 1 chr14:36835046-36835546 ( 74) AGAGAGAGGGAGTAAT 1 chr12:54359085-54359585 ( 73) AGAGACAGCGAAAGAG 1 chr17:58417458-58417958 ( 54) GGGGAGAGCGAAAGAA 1 chr5:37371026-37371526 ( 61) GGAGGGAGGGAAAGGA 1 chr19:4815136-4815636 ( 76) TGAGTGAGTGAATAAA 1 chr22:39520174-39520674 ( 64) AAAGGGAGGGAGGGAA 1 chr10:74826043-74826543 ( 42) TAGGAGAGAGAAAAAG 1 chr19:49580397-49580897 ( 85) AGAGAGAAAGAGAAGA 1 chr12:50111901-50112401 ( 12) GGTGGGAGGGAGAAAG 1 chr3:15427348-15427848 ( 48) TGGGGGTGAGAGAGGA 1 chr1:169893813-169894313 ( 75) TGGGGCAGTGAGTGAA 1 chr5:150449660-150450160 ( 30) AGGGAGAGCGAAAAGA 1 chr3:72887609-72888109 ( 52) TGGGTGTGTGAGTGAA 1 chr8:71355221-71355721 ( 24) AGTGACAGGGAATGAG 1 chr1:66924920-66925420 ( 57) GAGGGGAAGGAGAGAA 1 chr8:74350128-74350628 ( 74) TGTGGGAGGGAGAAGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 12.0056 E= 2.0e-020 122 -1155 -102 54 -78 -1155 168 -1155 147 -1155 -2 -119 -1155 -1155 188 -1155 122 -1155 43 -119 -278 -144 168 -1155 187 -1155 -1155 -46 -178 -1155 178 -1155 68 -144 15 3 -1155 -1155 188 -1155 213 -1155 -1155 -1155 54 -1155 130 -1155 154 -1155 -202 22 3 -1155 150 -1155 187 -1155 -70 -1155 113 -1155 68 -178 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 30 E= 2.0e-020 0.533333 0.000000 0.133333 0.333333 0.133333 0.000000 0.866667 0.000000 0.633333 0.000000 0.266667 0.100000 0.000000 0.000000 1.000000 0.000000 0.533333 0.000000 0.366667 0.100000 0.033333 0.100000 0.866667 0.000000 0.833333 0.000000 0.000000 0.166667 0.066667 0.000000 0.933333 0.000000 0.366667 0.100000 0.300000 0.233333 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.333333 0.000000 0.666667 0.000000 0.666667 0.000000 0.066667 0.266667 0.233333 0.000000 0.766667 0.000000 0.833333 0.000000 0.166667 0.000000 0.500000 0.000000 0.433333 0.066667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGAGRGAGDGARAGAR MEME-7 regular expression -------------------------------------------------------------------------------- [AT]G[AG]G[AG]GAG[AGT]GA[GA][AT][GA]A[AG] -------------------------------------------------------------------------------- Time 4610.26 secs. ******************************************************************************** ******************************************************************************** MOTIF CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 width = 31 sites = 11 llr = 319 E-value = 7.1e-038 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 Description -------------------------------------------------------------------------------- Simplified A :::9::1291a:813614989:2:9:::227 pos.-specific C a9a11:1518::111::21::81::::924: probability G ::::::1::1:a1:5494:111:a1aa::13 matrix T :1::9a74:::::81::1:1:17::::164: bits 2.1 * * 1.9 * * * ** * ** 1.7 * **** * ** * * **** 1.5 ****** * ** * * * ***** Relative 1.3 ****** * **** * *** ***** * Entropy 1.1 ****** ****** ** ********** * (41.9 bits) 0.9 ******* ****** ** *********** * 0.6 ******* ****** ** *********** * 0.4 ***************** *********** * 0.2 ******************************* 0.0 ------------------------------- Multilevel CCCATTTCACAGATGAGAAAACTGAGGCTCA consensus T AG G TG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------- chr22:24805653-24806153 + 32 1.92e-16 ccacattata cccattttaaagatgagaaaactgaggcttg gagaATATCG chr19:40403180-40403680 + 67 3.52e-16 tagaataagt cccatttcagagatgagaaaactgaggcaca gaa chr10:22616152-22616652 + 58 1.57e-15 tattatcatg cccattacacagataaggaaattgaggctta gtgagattag chr19:48513118-48513618 + 20 1.06e-14 tttaatcatg cccattgtacagatgaggcaactgaggcaca gcgcggggta chr19:39125128-39125628 - 6 1.28e-14 ATCATTAATA CCCATTTTACAGATAAAGAAACAGAGGTTCA GAGGG chr7:25893923-25894423 + 26 2.41e-14 acaagatagc cccatttaccagctgagcaaactgaggctaa aggttacttc chr19:30426854-30427354 - 64 2.88e-14 GATGTG CCCATTTTACAGATAGGTAAACAGAGGCCAG ATGGTAGGGG chr8:37600552-37601052 + 43 1.25e-13 GAAcaatcca cccatttcacagattgggagactggggccta gatatgggca chr11:67507644-67508144 + 25 3.52e-13 CGTGACCACG cccacttcacaggccagcaaactgaggctca gcgagggtag chr10:14691316-14691816 + 52 5.32e-13 ccttatcttc ctccttcaacagaagggaaaactgaggctta aaACATTAAA chr11:78188237-78188737 + 9 2.29e-12 atgccatc cccatttcacagatgggaatggcgaggctgg gatagattag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:24805653-24806153 1.9e-16 31_[+8]_38 chr19:40403180-40403680 3.5e-16 66_[+8]_3 chr10:22616152-22616652 1.6e-15 57_[+8]_12 chr19:48513118-48513618 1.1e-14 19_[+8]_50 chr19:39125128-39125628 1.3e-14 5_[-8]_64 chr7:25893923-25894423 2.4e-14 25_[+8]_44 chr19:30426854-30427354 2.9e-14 63_[-8]_6 chr8:37600552-37601052 1.3e-13 42_[+8]_27 chr11:67507644-67508144 3.5e-13 24_[+8]_45 chr10:14691316-14691816 5.3e-13 51_[+8]_18 chr11:78188237-78188737 2.3e-12 8_[+8]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCATTTYACAGATRRGVAAACTGAGGCTHA width=31 seqs=11 chr22:24805653-24806153 ( 32) CCCATTTTAAAGATGAGAAAACTGAGGCTTG 1 chr19:40403180-40403680 ( 67) CCCATTTCAGAGATGAGAAAACTGAGGCACA 1 chr10:22616152-22616652 ( 58) CCCATTACACAGATAAGGAAATTGAGGCTTA 1 chr19:48513118-48513618 ( 20) CCCATTGTACAGATGAGGCAACTGAGGCACA 1 chr19:39125128-39125628 ( 6) CCCATTTTACAGATAAAGAAACAGAGGTTCA 1 chr7:25893923-25894423 ( 26) CCCATTTACCAGCTGAGCAAACTGAGGCTAA 1 chr19:30426854-30427354 ( 64) CCCATTTTACAGATAGGTAAACAGAGGCCAG 1 chr8:37600552-37601052 ( 43) CCCATTTCACAGATTGGGAGACTGGGGCCTA 1 chr11:67507644-67508144 ( 25) CCCACTTCACAGGCCAGCAAACTGAGGCTCA 1 chr10:14691316-14691816 ( 52) CTCCTTCAACAGAAGGGAAAACTGAGGCTTA 1 chr11:78188237-78188737 ( 9) CCCATTTCACAGATGGGAATGGCGAGGCTGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 31 n= 42000 bayes= 11.4507 E= 7.1e-038 -1010 188 -1010 -1010 -1010 174 -1010 -133 -1010 188 -1010 -1010 199 -157 -1010 -1010 -1010 -157 -1010 199 -1010 -1010 -1010 213 -133 -157 -157 167 -33 74 -1010 67 199 -157 -1010 -1010 -133 159 -157 -1010 213 -1010 -1010 -1010 -1010 -1010 188 -1010 184 -157 -157 -1010 -133 -157 -1010 184 25 -157 101 -133 148 -1010 42 -1010 -133 -1010 174 -1010 67 -58 42 -133 199 -157 -1010 -1010 184 -1010 -157 -133 199 -1010 -157 -1010 -1010 159 -157 -133 -33 -157 -1010 167 -1010 -1010 188 -1010 199 -1010 -157 -1010 -1010 -1010 188 -1010 -1010 -1010 188 -1010 -1010 174 -1010 -133 -33 -58 -1010 148 -33 42 -157 67 167 -1010 1 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 31 nsites= 11 E= 7.1e-038 0.000000 1.000000 0.000000 0.000000 0.000000 0.909091 0.000000 0.090909 0.000000 1.000000 0.000000 0.000000 0.909091 0.090909 0.000000 0.000000 0.000000 0.090909 0.000000 0.909091 0.000000 0.000000 0.000000 1.000000 0.090909 0.090909 0.090909 0.727273 0.181818 0.454545 0.000000 0.363636 0.909091 0.090909 0.000000 0.000000 0.090909 0.818182 0.090909 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.818182 0.090909 0.090909 0.000000 0.090909 0.090909 0.000000 0.818182 0.272727 0.090909 0.545455 0.090909 0.636364 0.000000 0.363636 0.000000 0.090909 0.000000 0.909091 0.000000 0.363636 0.181818 0.363636 0.090909 0.909091 0.090909 0.000000 0.000000 0.818182 0.000000 0.090909 0.090909 0.909091 0.000000 0.090909 0.000000 0.000000 0.818182 0.090909 0.090909 0.181818 0.090909 0.000000 0.727273 0.000000 0.000000 1.000000 0.000000 0.909091 0.000000 0.090909 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.909091 0.000000 0.090909 0.181818 0.181818 0.000000 0.636364 0.181818 0.363636 0.090909 0.363636 0.727273 0.000000 0.272727 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCATTTYACAGATRRGVAAACTGAGGCTHA MEME-8 regular expression -------------------------------------------------------------------------------- CCCATTT[CT]ACAGAT[GA][AG]G[AG]AAACTGAGGCT[CT][AG] -------------------------------------------------------------------------------- Time 5229.95 secs. ******************************************************************************** ******************************************************************************** MOTIF GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 width = 48 sites = 5 llr = 270 E-value = 2.3e-024 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 Description -------------------------------------------------------------------------------- Simplified A 2::::::a:::::a:::a:::::::4:aaa2:a:a:2a6:::84:::: pos.-specific C ::2:2a6::a:2a::a8::::86a4:a::::::8:2:::828::8a2: probability G 8a::::::a::::::::::a::2::6::::8a::::6:2:::2::::: matrix T ::8a8:4:::a8::a:2:a:a22:6::::::::2:82:2282:62:8a bits 2.1 * * * ** ** * *** * * * * 1.9 * * * **** **** **** * **** ** * * * * 1.7 * * * **** **** **** * **** ** * * * * 1.5 * * * **** **** **** * **** ** * * * * Relative 1.3 ****** *************** * ********** * **** **** Entropy 1.1 ********************** ************* * ********* (77.9 bits) 0.9 ********************** ************* * ********* 0.6 ************************************************ 0.4 ************************************************ 0.2 ************************************************ 0.0 ------------------------------------------------ Multilevel GGTTTCCAGCTTCATCCATGTCCCTGCAAAGGACATGAACTCATCCTT consensus A C C T C T TG CA A T CA GTCTGAT C sequence T T T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------------------------ chr10:126172706-12617320 - 27 4.88e-27 TAAGAATGAT GGTTTCTAGCTTCATCCATGTCCCCACAAAGGACATGAGCTCAACCTT TTTTATGGCT chr1:241425033-241425533 + 37 1.80e-26 tgagaatgat ggtttccagcttcatccatgtccccgcaaaggatatgaacccatcctt ttttatggct chr1:231728927-231729427 + 4 1.80e-26 gat ggtttctagcttcatccatgtccctacaaaggacacaaactcaacctt ttttatggct chr1:203314359-203314859 - 46 1.79e-25 GAATGAT AGTTCCCAGCTTCATCCATGTCTCTGCAAAGGACATGAATTCATCCTT TTTTATGGCT chr19:40829105-40829605 + 24 4.61e-22 ttaggatagt ggcttccagctccatctatgttgctgcaaaagacattatcttgttcct ttttatggct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:126172706-12617320 4.9e-27 26_[-9]_26 chr1:241425033-241425533 1.8e-26 36_[+9]_16 chr1:231728927-231729427 1.8e-26 3_[+9]_49 chr1:203314359-203314859 1.8e-25 45_[-9]_7 chr19:40829105-40829605 4.6e-22 23_[+9]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT width=48 seqs=5 chr10:126172706-12617320 ( 27) GGTTTCTAGCTTCATCCATGTCCCCACAAAGGACATGAGCTCAACCTT 1 chr1:241425033-241425533 ( 37) GGTTTCCAGCTTCATCCATGTCCCCGCAAAGGATATGAACCCATCCTT 1 chr1:231728927-231729427 ( 4) GGTTTCTAGCTTCATCCATGTCCCTACAAAGGACACAAACTCAACCTT 1 chr1:203314359-203314859 ( 46) AGTTCCCAGCTTCATCCATGTCTCTGCAAAGGACATGAATTCATCCTT 1 chr19:40829105-40829605 ( 24) GGCTTCCAGCTCCATCTATGTTGCTGCAAAAGACATTATCTTGTTCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 48 n= 31800 bayes= 12.0689 E= 2.3e-024 -19 -897 156 -897 -897 -897 188 -897 -897 -44 -897 180 -897 -897 -897 213 -897 -44 -897 180 -897 188 -897 -897 -897 114 -897 81 213 -897 -897 -897 -897 -897 188 -897 -897 188 -897 -897 -897 -897 -897 213 -897 -44 -897 180 -897 188 -897 -897 213 -897 -897 -897 -897 -897 -897 213 -897 188 -897 -897 -897 156 -897 -19 213 -897 -897 -897 -897 -897 -897 213 -897 -897 188 -897 -897 -897 -897 213 -897 156 -897 -19 -897 114 -44 -19 -897 188 -897 -897 -897 56 -897 139 81 -897 114 -897 -897 188 -897 -897 213 -897 -897 -897 213 -897 -897 -897 213 -897 -897 -897 -19 -897 156 -897 -897 -897 188 -897 213 -897 -897 -897 -897 156 -897 -19 213 -897 -897 -897 -897 -44 -897 180 -19 -897 114 -19 213 -897 -897 -897 139 -897 -44 -19 -897 156 -897 -19 -897 -44 -897 180 -897 156 -897 -19 180 -897 -44 -897 81 -897 -897 139 -897 156 -897 -19 -897 188 -897 -897 -897 -44 -897 180 -897 -897 -897 213 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 48 nsites= 5 E= 2.3e-024 0.200000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.200000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 0.000000 0.200000 0.000000 0.800000 0.000000 1.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.400000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.200000 0.000000 0.800000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.800000 0.000000 0.200000 0.000000 0.600000 0.200000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.600000 0.400000 0.000000 0.600000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 1.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.800000 0.200000 0.000000 0.600000 0.200000 1.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.200000 0.200000 0.000000 0.800000 0.000000 0.200000 0.000000 0.200000 0.000000 0.800000 0.000000 0.800000 0.000000 0.200000 0.800000 0.000000 0.200000 0.000000 0.400000 0.000000 0.000000 0.600000 0.000000 0.800000 0.000000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.800000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGTTTCYAGCTTCATCCATGTCCCYRCAAAGGACATGAACTCAWCCTT MEME-9 regular expression -------------------------------------------------------------------------------- [GA]G[TC]T[TC]C[CT]AGCT[TC]CATC[CT]ATGT[CT][CGT]C[TC][GA]CAAA[GA]GA[CT]A[TC][GAT]A[AGT][CT][TC][CT][AG][TA][CT]C[TC]T -------------------------------------------------------------------------------- Time 5826.58 secs. ******************************************************************************** ******************************************************************************** MOTIF BAAAYAMAYAMAHAMAHAHACA MEME-10 width = 22 sites = 28 llr = 405 E-value = 5.5e-018 ******************************************************************************** -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 Description -------------------------------------------------------------------------------- Simplified A :87a:85a18593669464838 pos.-specific C 3:3:515:5:51513:4:3161 probability G 3:::21:::2:::1:::2:::1 matrix T 43::3:::4:::31:1324111 bits 2.1 1.9 * * 1.7 * * * 1.5 * * * * Relative 1.3 * * * * * * Entropy 1.1 *** * * * * * * (20.9 bits) 0.9 *** * * *** ** * * 0.6 *** ******* *** * * * 0.4 ********************* 0.2 ********************** 0.0 ---------------------- Multilevel TAAACAAACAAACAAAAATACA consensus CTC T C TGC T C CGA A sequence G A TTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr1:220527612-220528112 + 13 1.83e-12 ATGAAACGGa caaacaaacaaacaaacaaaca aaAACAGaaa chr14:21383838-21384338 - 46 1.23e-11 AAAAACAAAA CAAACAAACAAACAAAAAAAAA ACCTAACGCT chr19:35881941-35882441 + 35 1.10e-10 aaataaaaaa taaataaataaataaataaata aataaataaa chr5:160008682-160009182 + 1 1.10e-10 . taaataaataaataaataaata GTGAAACGAA chr10:87878916-87879416 - 2 5.05e-10 TTAAAATACA CACACACACACACACATATACA C chr10:101442053-10144255 - 46 5.91e-10 TTATCTCATT TACACACACACACACACACACA CATACACACA chr19:38243751-38244251 + 3 2.47e-09 aa caaagaaataaaataaaataaa aCCAATTCAC chr12:48021658-48022158 + 37 3.23e-09 CAATGGACCC TAAACAAACACATTAACAACCA CTCAGAGACC chr8:16825859-16826359 + 7 8.70e-09 CAGATa cacacacacgcacacacacaca cacagacata chr12:106075002-10607550 + 78 1.55e-08 GAAAGCAGTA TTAATCAacacacacacacaca c chr7:99616252-99616752 + 58 7.25e-08 tccctgacTa cacatacacacacgcacgcaca cTACCCGGGG chr1:70143202-70143702 - 66 8.76e-08 ACTATGCAGT GAAATGCATGCATTAATATACA ATATGTCTAT chr17:32015510-32016010 - 5 9.61e-08 TTCAACCAAT GACACCCATAAACAAAAGTACC CGCC chr7:83267080-83267580 - 59 1.38e-07 AAAAAAATGT TTAACAAATAAAACATTGTAAA ACCTTCAGCT chr10:12195795-12196295 - 54 1.65e-07 GCATACGCTT GACACACACGCATACAAAAAGA GCTTTAGTCT chr1:214520530-214521030 + 46 1.80e-07 AAGTGCCTTG TAAATAAATACAAAACATTTCA CCAGTTCACT chr19:36916363-36916863 - 77 1.96e-07 CT CACACACACAACCACACACCCA CACTAACTCC chr16:25049544-25050044 + 60 2.75e-07 ctataaaagt gtaacacatacaattatgtaca atacatgaaa chr5:124740935-124741435 - 15 4.12e-07 CGCCACTCCC TTAATACGTGAACAAAATCAAA ACATGCCATA chr1:76294443-76294943 - 42 4.45e-07 CAAAGCCCTT GAAATGCAAAAAAAAACTTACT CTTTTCTGAC chr1:210081442-210081942 + 3 5.20e-07 aa taaagcaaagcacaataaaaca tgatatgtct chr1:215581849-215582349 - 71 8.14e-07 TAAATCTC ATACCACATACAAAAAAGTAAA CTCCACAAGG chr1:217630924-217631424 + 60 8.14e-07 TCGCAGTAGA GACAGAGACAAATAAATTAAAC TTTTGTGCTA chr8:25998493-25998993 + 57 1.99e-06 TAAAGGTTAA CAAAGAAATAACTCAAATTATC ATCTCAGGGA chr3:72887609-72888109 + 76 1.99e-06 AATGGGGAAG TAaacgaacgaacgaacgaatg aat chr19:30426854-30427354 + 1 2.26e-06 . GTAAGACACAGATGCATATcca ctaacttgct chr1:226944558-226945058 - 28 2.57e-06 GCCTCCCTTC TACACATACACACACACTCTCT CTCTCTCACT chr12:54052074-54052574 + 70 2.91e-06 CAGATTTAGT CTAATAAATAAAACATAAACAG TTAACTTTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:220527612-220528112 1.8e-12 12_[+10]_66 chr14:21383838-21384338 1.2e-11 45_[-10]_33 chr19:35881941-35882441 1.1e-10 34_[+10]_44 chr5:160008682-160009182 1.1e-10 [+10]_78 chr10:87878916-87879416 5.1e-10 1_[-10]_77 chr10:101442053-10144255 5.9e-10 45_[-10]_33 chr19:38243751-38244251 2.5e-09 2_[+10]_76 chr12:48021658-48022158 3.2e-09 36_[+10]_42 chr8:16825859-16826359 8.7e-09 6_[+10]_72 chr12:106075002-10607550 1.5e-08 77_[+10]_1 chr7:99616252-99616752 7.2e-08 57_[+10]_21 chr1:70143202-70143702 8.8e-08 65_[-10]_13 chr17:32015510-32016010 9.6e-08 4_[-10]_74 chr7:83267080-83267580 1.4e-07 58_[-10]_20 chr10:12195795-12196295 1.7e-07 53_[-10]_25 chr1:214520530-214521030 1.8e-07 45_[+10]_33 chr19:36916363-36916863 2e-07 76_[-10]_2 chr16:25049544-25050044 2.7e-07 59_[+10]_19 chr5:124740935-124741435 4.1e-07 14_[-10]_64 chr1:76294443-76294943 4.5e-07 41_[-10]_37 chr1:210081442-210081942 5.2e-07 2_[+10]_76 chr1:215581849-215582349 8.1e-07 70_[-10]_8 chr1:217630924-217631424 8.1e-07 59_[+10]_19 chr8:25998493-25998993 2e-06 56_[+10]_22 chr3:72887609-72888109 2e-06 75_[+10]_3 chr19:30426854-30427354 2.3e-06 [+10]_78 chr1:226944558-226945058 2.6e-06 27_[-10]_51 chr12:54052074-54052574 2.9e-06 69_[+10]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BAAAYAMAYAMAHAMAHAHACA width=22 seqs=28 chr1:220527612-220528112 ( 13) CAAACAAACAAACAAACAAACA 1 chr14:21383838-21384338 ( 46) CAAACAAACAAACAAAAAAAAA 1 chr19:35881941-35882441 ( 35) TAAATAAATAAATAAATAAATA 1 chr5:160008682-160009182 ( 1) TAAATAAATAAATAAATAAATA 1 chr10:87878916-87879416 ( 2) CACACACACACACACATATACA 1 chr10:101442053-10144255 ( 46) TACACACACACACACACACACA 1 chr19:38243751-38244251 ( 3) CAAAGAAATAAAATAAAATAAA 1 chr12:48021658-48022158 ( 37) TAAACAAACACATTAACAACCA 1 chr8:16825859-16826359 ( 7) CACACACACGCACACACACACA 1 chr12:106075002-10607550 ( 78) TTAATCAACACACACACACACA 1 chr7:99616252-99616752 ( 58) CACATACACACACGCACGCACA 1 chr1:70143202-70143702 ( 66) GAAATGCATGCATTAATATACA 1 chr17:32015510-32016010 ( 5) GACACCCATAAACAAAAGTACC 1 chr7:83267080-83267580 ( 59) TTAACAAATAAAACATTGTAAA 1 chr10:12195795-12196295 ( 54) GACACACACGCATACAAAAAGA 1 chr1:214520530-214521030 ( 46) TAAATAAATACAAAACATTTCA 1 chr19:36916363-36916863 ( 77) CACACACACAACCACACACCCA 1 chr16:25049544-25050044 ( 60) GTAACACATACAATTATGTACA 1 chr5:124740935-124741435 ( 15) TTAATACGTGAACAAAATCAAA 1 chr1:76294443-76294943 ( 42) GAAATGCAAAAAAAAACTTACT 1 chr1:210081442-210081942 ( 3) TAAAGCAAAGCACAATAAAACA 1 chr1:215581849-215582349 ( 71) ATACCACATACAAAAAAGTAAA 1 chr1:217630924-217631424 ( 60) GACAGAGACAAATAAATTAAAC 1 chr8:25998493-25998993 ( 57) CAAAGAAATAACTCAAATTATC 1 chr3:72887609-72888109 ( 76) TAAACGAACGAACGAACGAATG 1 chr19:30426854-30427354 ( 1) GTAAGACACAGATGCATATCCA 1 chr1:226944558-226945058 ( 28) TACACATACACACACACTCTCT 1 chr12:54052074-54052574 ( 70) CTAATAAATAAAACATAAACAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 12.6844 E= 5.5e-018 -268 24 -12 78 171 -1145 -1145 13 157 24 -1145 -1145 208 -292 -1145 -1145 -1145 88 -60 49 178 -134 -134 -1145 102 77 -292 -268 208 -1145 -292 -1145 -168 88 -1145 91 178 -1145 -34 -1145 113 77 -292 -1145 202 -192 -1145 -1145 13 77 -1145 32 149 -134 -134 -68 149 24 -1145 -268 191 -292 -1145 -109 64 40 -1145 32 132 -1145 -34 -9 64 -12 -1145 78 178 -92 -1145 -168 13 107 -292 -68 171 -134 -192 -168 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 28 E= 5.5e-018 0.035714 0.321429 0.250000 0.392857 0.750000 0.000000 0.000000 0.250000 0.678571 0.321429 0.000000 0.000000 0.964286 0.035714 0.000000 0.000000 0.000000 0.500000 0.178571 0.321429 0.785714 0.107143 0.107143 0.000000 0.464286 0.464286 0.035714 0.035714 0.964286 0.000000 0.035714 0.000000 0.071429 0.500000 0.000000 0.428571 0.785714 0.000000 0.214286 0.000000 0.500000 0.464286 0.035714 0.000000 0.928571 0.071429 0.000000 0.000000 0.250000 0.464286 0.000000 0.285714 0.642857 0.107143 0.107143 0.142857 0.642857 0.321429 0.000000 0.035714 0.857143 0.035714 0.000000 0.107143 0.357143 0.357143 0.000000 0.285714 0.571429 0.000000 0.214286 0.214286 0.357143 0.250000 0.000000 0.392857 0.785714 0.142857 0.000000 0.071429 0.250000 0.571429 0.035714 0.142857 0.750000 0.107143 0.071429 0.071429 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAAAYAMAYAMAHAMAHAHACA MEME-10 regular expression -------------------------------------------------------------------------------- [TCG][AT][AC]A[CT]A[AC]A[CT][AG][AC]A[CTA]A[AC]A[ACT][AGT][TAC]A[CA]A -------------------------------------------------------------------------------- Time 6400.66 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:45464572-45465072 8.41e-03 51_[-1(8.88e-06)]_37 chr6:27544050-27544550 7.93e-29 9_[-4(4.84e-14)]_6_[+2(6.43e-17)]_\ [+3(3.41e-12)] chr6:27505640-27506140 6.29e-01 100 chr1:167162990-167163490 5.00e-01 100 chr15:66504691-66505191 9.11e-02 26_[+10(1.97e-05)]_52 chr10:7302332-7302832 1.40e-01 100 chr7:117123511-117124011 5.23e-02 42_[+4(2.34e-06)]_27 chr16:1271683-1272183 9.92e-01 100 chr10:8534078-8534578 1.02e-01 6_[-9(5.52e-06)]_46 chr1:146038290-146038790 1.18e-24 1_[+3(6.68e-10)]_[+5(7.28e-16)]_11_\ [-4(7.99e-14)]_4 chr8:71355221-71355721 2.12e-03 23_[+7(2.22e-06)]_61 chr16:25055673-25056173 2.02e-28 4_[-3(1.22e-13)]_2_[-2(1.03e-18)]_7_\ [+4(2.88e-14)]_2 chr19:45450372-45450872 5.65e-16 16_[+4(5.29e-15)]_7_[-5(5.01e-14)]_\ 15 chr1:44213173-44213673 3.01e-01 42_[-1(8.55e-07)]_28_[-1(8.03e-05)]_\ 6 chr6:57317393-57317893 9.61e-02 23_[+1(2.08e-06)]_65 chr6:4021022-4021522 7.40e-02 100 chr5:88516234-88516734 3.40e-01 [-4(1.82e-05)]_69 chr1:43172076-43172576 1.34e-02 27_[+1(2.65e-05)]_13_[+1(3.88e-07)]_\ 36 chr19:5720087-5720587 2.82e-02 22_[+1(3.58e-06)]_21_[+1(5.44e-05)]_\ 33 chr1:25998103-25998603 2.33e-04 78_[+3(1.56e-08)] chr1:200620580-200621080 9.84e-02 37_[-1(1.76e-05)]_51 chr10:14691316-14691816 2.23e-07 51_[+8(5.32e-13)]_18 chr8:37600552-37601052 3.41e-07 42_[+8(1.25e-13)]_27 chr12:131710722-13171122 3.20e-01 13_[-9(6.11e-05)]_39 chr10:101442053-10144255 7.15e-12 10_[-7(8.12e-10)]_13_\ [-10(4.31e-10)]_39 chr15:69143744-69144244 2.62e-01 100 chr12:89525902-89526402 1.84e-01 100 chr11:64268972-64269472 4.66e-01 52_[+1(8.03e-05)]_36 chr3:13265438-13265938 3.78e-01 66_[+8(8.48e-05)]_3 chr3:123585177-123585677 1.78e-02 36_[-7(6.62e-05)]_48 chr9:18976719-18977219 5.05e-03 34_[-5(9.71e-05)]_3_[-4(2.06e-05)]_\ 1 chr1:70143202-70143702 1.05e-02 65_[-10(8.76e-08)]_13 chr3:57597454-57597954 4.63e-01 100 chr6:28795904-28796404 2.20e-01 100 chr18:59079492-59079992 9.31e-02 100 chr19:38004418-38004918 9.05e-01 100 chr17:18087671-18088171 1.51e-01 58_[+1(2.65e-05)]_30 chr11:64317420-64317920 3.59e-04 6_[-1(1.25e-07)]_82 chr3:9194488-9194988 5.69e-03 47_[+4(3.86e-05)]_22 chr11:62653149-62653649 5.93e-01 100 chr17:58417458-58417958 1.36e-03 [+9(2.20e-05)]_5_[-7(6.15e-07)]_31 chr5:99900430-99900930 5.48e-02 100 chr19:37506800-37507300 2.13e-01 100 chr9:86141743-86142243 1.48e-01 100 chr19:45406301-45406801 1.90e-01 100 chr6:28752275-28752775 1.38e-21 26_[+4(5.50e-19)]_11_[-5(1.66e-14)]_\ 1 chr15:96693934-96694434 3.12e-01 100 chr1:198837515-198838015 5.72e-01 100 chr3:156161110-156161610 2.11e-03 44_[-4(5.32e-09)]_25 chr1:205122023-205122523 2.56e-01 100 chr1:161153901-161154401 1.92e-01 100 chr9:85743169-85743669 2.64e-02 71_[-10(6.03e-05)]_7 chr2:3574953-3575453 2.72e-01 83_[+1(7.44e-05)]_5 chr22:35299697-35300197 4.76e-01 100 chr5:94469749-94470249 3.96e-01 100 chr6:26571611-26572111 7.84e-04 38_[-6(1.86e-05)]_40 chr3:120742351-120742851 8.62e-01 100 chr11:78188237-78188737 1.92e-06 8_[+8(2.29e-12)]_61 chr22:21567259-21567759 6.68e-01 100 chr18:22184439-22184939 3.78e-17 27_[-4(1.29e-13)]_6_[+2(1.12e-13)]_\ 4 chr17:30906030-30906530 7.10e-02 5_[+1(8.55e-07)]_83 chr19:36772817-36773317 3.34e-02 71_[+1(1.75e-06)]_17 chr17:45148368-45148868 2.77e-01 100 chr5:69521149-69521649 1.47e-01 100 chr8:16825859-16826359 7.09e-04 6_[+10(8.70e-09)]_8_[+10(3.67e-09)]_\ 1_[-7(2.34e-05)]_25 chr5:122333029-122333529 4.50e-02 22_[+4(5.23e-05)]_47 chr16:89657416-89657916 4.40e-01 76_[+1(2.19e-05)]_12 chr12:124914556-12491505 3.61e-01 100 chr1:17236669-17237169 8.50e-01 100 chr11:62841269-62841769 1.60e-01 100 chr5:10543711-10544211 2.10e-16 12_[-3(8.20e-13)]_2_[-2(2.05e-17)]_\ 32 chr1:61091455-61091955 5.49e-01 100 chr1:150487007-150487507 2.08e-02 35_[+1(3.23e-05)]_53 chr6:26204279-26204779 7.39e-01 100 chr12:121531299-12153179 1.01e-01 58_[-2(9.84e-05)]_10 chr1:45499908-45500408 1.13e-04 9_[+6(3.51e-05)]_35_[-6(2.57e-09)]_\ 12 chr12:4538386-4538886 3.14e-01 61_[-4(4.14e-05)]_8 chr8:11201481-11201981 5.75e-01 100 chr2:63588566-63589066 1.48e-01 55_[+6(1.07e-05)]_23 chr12:56007133-56007633 1.32e-01 35_[+3(5.05e-05)]_43 chr5:181174436-181174936 7.21e-16 29_[+2(1.85e-17)]_[+3(5.75e-12)]_17 chr6:24774937-24775437 7.31e-01 100 chr17:66508769-66509269 3.99e-02 39_[+6(9.79e-05)]_39 chrX:101407964-101408464 5.68e-01 100 chr19:38243751-38244251 4.69e-04 2_[+10(2.47e-09)]_76 chr6:82877126-82877626 8.02e-01 100 chr1:1615150-1615650 1.77e-01 63_[+1(2.08e-06)]_25 chr10:96129696-96130196 2.47e-01 78_[+1(5.44e-05)]_10 chr2:132884661-132885161 7.71e-01 100 chr1:148522556-148523056 3.88e-01 100 chr1:16545751-16546251 3.25e-01 100 chr18:3297278-3297778 6.00e-01 100 chr10:22616152-22616652 4.15e-08 57_[+8(1.57e-15)]_12 chr19:7522282-7522782 4.13e-01 100 chr15:66886250-66886750 3.17e-01 100 chr1:68217023-68217523 7.72e-01 100 chrX:71366023-71366523 3.56e-03 15_[+1(2.65e-05)]_4_[-3(7.02e-05)]_\ 26_[+1(7.80e-06)]_9 chr10:47553220-47553720 2.89e-01 100 chr19:3761735-3762235 7.53e-03 52_[-1(5.19e-06)]_36 chr17:4940242-4940742 1.50e-02 43_[-1(1.75e-06)]_45 chr19:40829105-40829605 1.78e-14 23_[+9(4.61e-22)]_29 chr15:75368377-75368877 2.33e-01 100 chr19:49580397-49580897 4.13e-04 23_[-1(4.37e-06)]_49_[-7(1.09e-06)] chr19:39212342-39212842 1.21e-01 100 chr14:20662970-20663470 3.73e-01 23_[+2(6.01e-05)]_45 chr5:160008682-160009182 2.78e-04 [+10(1.10e-10)]_78 chr19:10194308-10194808 4.81e-01 9_[-1(5.91e-05)]_79 chr1:16644456-16644956 9.39e-01 100 chr6:16628560-16629060 2.32e-04 46_[-4(8.44e-10)]_23 chr22:24805653-24806153 9.77e-12 31_[+8(1.92e-16)]_38 chr19:11536146-11536646 7.09e-01 100 chr1:161764895-161765395 3.82e-18 24_[+3(2.66e-13)]_[+5(9.56e-18)]_23 chr1:33127058-33127558 3.15e-01 34_[+1(3.87e-05)]_54 chr19:2702759-2703259 4.66e-01 100 chr1:81126903-81127403 8.97e-01 100 chr12:124922496-12492299 9.01e-15 10_[-4(2.87e-06)]_10_[+2(1.12e-19)]_\ 17 chr16:52553254-52553754 8.35e-01 100 chr10:12195795-12196295 7.69e-03 53_[-10(1.65e-07)]_25 chr12:109477296-10947779 7.04e-02 100 chr5:181218376-181218876 2.49e-17 10_[-3(1.31e-11)]_[-2(1.76e-16)]_36 chr6:26285259-26285759 5.11e-02 59_[+8(8.00e-05)]_10 chr16:77409299-77409799 4.62e-01 100 chr1:241847803-241848303 1.80e-01 52_[-8(8.00e-05)]_17 chr6:28757402-28757902 1.66e-13 16_[+3(6.25e-10)]_[+5(2.38e-16)]_31 chr6:4320861-4321361 1.04e-01 100 chr1:173824292-173824792 5.95e-01 100 chr1:220527612-220528112 8.78e-10 12_[+10(1.83e-12)]_10_\ [+10(1.08e-06)]_17_[-7(1.08e-07)]_1 chrX:153928079-153928579 2.52e-02 63_[-1(6.79e-06)]_25 chr4:110904615-110905115 7.33e-01 100 chr19:48351416-48351916 6.10e-01 100 chr11:4094491-4094991 9.25e-01 100 chr1:11178257-11178757 9.02e-01 100 chr1:228079465-228079965 1.11e-01 75_[-3(3.61e-05)]_3 chr16:67935672-67936172 3.00e-03 100 chr19:10653772-10654272 9.50e-01 100 chr6:30488891-30489391 6.93e-15 7_[+5(3.93e-14)]_11_[-4(2.87e-13)]_\ 20 chr17:47895748-47896248 1.09e-01 100 chr16:29943962-29944462 6.44e-01 100 chr5:92552209-92552709 1.28e-01 100 chr10:33325910-33326410 2.46e-01 100 chr6:26327380-26327880 2.43e-01 100 chr9:133030677-133031177 7.62e-01 100 chr16:807577-808077 2.86e-01 30_[+1(3.55e-05)]_58 chr8:74350128-74350628 1.74e-02 48_[-1(2.39e-05)]_13_[+7(6.10e-06)]_\ 11 chr5:173887925-173888425 1.63e-01 100 chr8:37393077-37393577 1.38e-02 50_[-8(8.81e-05)]_19 chr10:129440198-12944069 5.09e-02 42_[-7(6.87e-05)]_42 chr2:232550398-232550898 2.45e-03 39_[-1(3.88e-07)]_27_[-1(3.55e-05)]_\ 10 chr1:234373224-234373724 3.49e-02 9_[-1(4.63e-05)]_79 chr1:36224038-36224538 1.82e-03 65_[+6(3.96e-09)]_13 chr8:33484925-33485425 2.51e-01 48_[-1(4.37e-06)]_40 chr13:52194233-52194733 7.97e-05 22_[+1(8.88e-06)]_5_[+3(1.31e-05)]_\ 39 chr2:219597715-219598215 1.15e-02 100 chr3:15427348-15427848 3.02e-03 13_[-1(4.99e-05)]_22_[-7(1.27e-06)]_\ 37 chr2:55232246-55232746 2.37e-02 100 chr1:231418041-231418541 2.73e-01 [+4(4.55e-05)]_69 chr15:89893816-89894316 5.18e-02 1_[+1(3.88e-07)]_87 chr19:41439616-41440116 9.28e-01 100 chr1:179882537-179883037 1.94e-03 29_[+1(3.55e-05)]_11_[+7(3.55e-07)]_\ 32 chr6:26537260-26537760 3.35e-01 65_[-6(6.22e-06)]_13 chr12:104630041-10463054 1.84e-01 100 chr8:27311314-27311814 1.66e-01 65_[+1(2.39e-05)]_23 chrX:49269204-49269704 6.29e-01 100 chr19:33312748-33313248 9.26e-07 19_[+4(2.50e-10)]_2_[-9(5.23e-05)] chr11:65418829-65419329 2.89e-01 100 chr18:50629066-50629566 4.68e-01 100 chr17:63773561-63774061 5.41e-01 100 chr7:83267080-83267580 4.99e-04 19_[-10(1.05e-05)]_17_\ [-10(1.38e-07)]_20 chr13:30617633-30618133 4.82e-01 74_[-1(3.23e-05)]_14 chr19:39390711-39391211 6.75e-01 100 chr18:59053314-59053814 3.11e-01 100 chr15:75335800-75336300 7.51e-02 47_[-1(2.93e-05)]_7_[-8(9.88e-05)]_\ 3 chr3:13650174-13650674 9.42e-01 100 chr12:114914302-11491480 9.26e-01 100 chr21:29073505-29074005 3.79e-01 100 chr8:81089411-81089911 1.65e-01 100 chr12:48021658-48022158 2.16e-04 36_[+10(3.23e-09)]_42 chr14:30621969-30622469 2.46e-03 69_[-8(6.84e-05)] chr11:18526680-18527180 4.37e-02 39_[-1(6.38e-05)]_13_[+1(1.45e-05)]_\ 8_[+1(5.19e-06)]_4 chr5:53478397-53478897 3.40e-02 24_[+7(4.25e-07)]_4_[+7(2.34e-05)]_\ 11_[+7(8.59e-05)]_13 chr14:70359509-70360009 5.62e-01 100 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6_[+1(8.55e-07)]_3_[+1(1.02e-05)]_\ 67 chr17:34981748-34982248 1.47e-01 100 chr6:30907512-30908012 4.74e-25 13_[+2(3.29e-18)]_1_[+3(7.23e-09)]_\ [+5(1.74e-15)]_1 chr19:1383558-1384058 7.60e-01 61_[+1(4.63e-05)]_27 chr12:69470130-69470630 1.10e-01 5_[+1(3.87e-05)]_22_[-1(1.76e-05)]_\ 49 chrX:53225080-53225580 1.63e-01 45_[-10(4.60e-05)]_33 chr16:30957565-30958065 6.12e-01 100 chr1:20507949-20508449 4.28e-02 26_[-1(6.50e-07)]_19_[-1(4.99e-05)]_\ 31 chr1:169893813-169894313 1.48e-02 74_[-7(1.37e-06)]_10 chr19:4233339-4233839 6.48e-01 100 chr9:36190642-36191142 1.68e-03 73_[+1(3.87e-05)]_15 chr12:12266881-12267381 1.86e-01 18_[+3(8.43e-05)]_60 chr6:26313804-26314304 1.12e-09 32_[+4(9.59e-15)]_37 chr19:48644710-48645210 1.34e-05 14_[-6(2.88e-12)]_42_[+6(5.96e-09)] chr14:74881627-74882127 2.50e-02 64_[+1(3.88e-07)]_24 chr12:110450055-11045055 7.64e-02 58_[+1(1.11e-06)]_30 chr5:134367031-134367531 1.88e-01 100 chr12:6764237-6764737 9.48e-02 100 chr15:40382678-40383178 2.72e-02 46_[-1(1.60e-05)]_42 chr6:7389575-7390075 9.52e-02 10_[+1(1.60e-05)]_11_[+1(4.37e-06)]_\ 55 chr19:50134119-50134619 3.17e-14 25_[+4(4.13e-11)]_10_[-5(1.23e-14)]_\ 3 chr5:83077349-83077849 4.19e-02 41_[-1(5.91e-06)]_17_[-1(3.23e-05)]_\ 18 chr17:40054131-40054631 3.14e-01 100 chr5:176388748-176389248 2.41e-01 67_[+7(8.27e-05)]_17 chr19:11435313-11435813 2.37e-02 85_[-1(8.55e-07)]_3 chr12:6493133-6493633 1.28e-01 24_[+1(3.16e-06)]_2_[-1(9.95e-05)]_\ 50 chrX:85003641-85004141 2.53e-01 100 chr6:38974724-38975224 1.44e-01 100 chr5:110738752-110739252 1.03e-01 20_[+1(6.79e-06)]_8_[+1(1.75e-06)]_\ 48 chr10:97401107-97401607 9.95e-02 38_[+1(2.93e-05)]_27_[+1(6.38e-05)]_\ 11 chr19:34218180-34218680 3.33e-02 100 chr16:31033104-31033604 2.39e-02 100 chr6:28790329-28790829 2.27e-04 12_[-3(1.55e-10)]_66 chr1:241425033-241425533 1.41e-19 36_[+9(1.80e-26)]_16 chr19:41859680-41860180 7.75e-01 100 chr1:146039400-146039900 1.79e-15 24_[-5(5.21e-17)]_[-3(2.97e-12)]_23 chr10:44752829-44753329 3.24e-01 100 chr5:124740935-124741435 2.17e-02 14_[-10(4.12e-07)]_64 chrX:54182128-54182628 8.37e-01 100 chr17:18315057-18315557 8.40e-02 [+1(6.79e-06)]_38_[-3(8.24e-05)]_28 chr18:22493140-22493640 6.19e-01 100 chr1:233241731-233242231 1.34e-01 31_[+10(3.19e-05)]_47 chr14:21383838-21384338 7.79e-10 18_[+1(6.79e-06)]_15_\ [-10(1.23e-11)]_33 chr15:65517429-65517929 1.45e-02 53_[+1(1.25e-07)]_35 chr17:50372899-50373399 9.30e-03 84_[+1(1.92e-07)]_4 chr19:43596374-43596874 9.67e-02 100 chr1:169483464-169483964 1.07e-01 10_[-6(3.42e-05)]_68 chr1:40948867-40949367 1.77e-01 50_[-9(1.41e-05)]_2 chr16:30697959-30698459 8.08e-01 100 chr3:183884631-183885131 6.98e-02 69_[+1(1.99e-05)]_19 chr19:8389771-8390271 4.71e-01 100 chr19:41310147-41310647 6.38e-01 100 chr10:104338335-10433883 3.44e-01 7_[-9(8.33e-05)]_45 chr16:30598283-30598783 2.05e-24 7_[-3(2.51e-11)]_2_[-2(6.25e-19)]_6_\ [+4(6.26e-12)] chr1:76294443-76294943 3.99e-03 41_[-10(4.45e-07)]_37 chr9:133417832-133418332 4.95e-01 100 chr3:129160952-129161452 3.38e-02 76_[-1(3.87e-05)]_12 chr15:41774262-41774762 3.33e-01 100 chr12:54359085-54359585 2.24e-02 72_[+7(6.15e-07)]_12 chr6:31541900-31542400 5.14e-02 100 chr19:39125128-39125628 1.49e-09 5_[-8(1.28e-14)]_64 chr10:15796033-15796533 6.17e-01 100 chr14:61331985-61332485 2.10e-04 6_[-6(7.25e-08)]_72 chr12:50111901-50112401 9.23e-04 11_[+7(1.27e-06)]_13_[-2(1.86e-05)]_\ 28 chr6:28136607-28137107 4.35e-03 26_[-1(3.88e-07)]_62 chr6:27545511-27546011 6.06e-01 100 chr19:39411939-39412439 7.87e-02 30_[+2(4.15e-05)]_38 chr19:40055913-40056413 1.44e-01 100 chr6:143755246-143755746 6.25e-01 100 chr16:67872821-67873321 6.96e-04 12_[+2(1.89e-06)]_1_[-1(4.25e-05)]_\ 43 chr19:17075294-17075794 6.81e-01 100 chr2:173449084-173449584 6.96e-01 100 chr19:39033019-39033519 1.50e-16 10_[-3(2.54e-12)]_2_[-2(8.96e-18)]_\ 34 chr3:181328953-181329453 3.77e-01 100 chr1:109984491-109984991 7.79e-02 3_[-7(4.22e-05)]_81 chr19:44071882-44072382 7.99e-06 4_[+6(5.29e-11)]_21_[+1(1.99e-05)]_\ 41 chr19:4723723-4724223 1.82e-01 38_[+1(3.55e-05)]_50 chr21:28992753-28993253 3.13e-01 100 chr8:37360439-37360939 2.46e-02 100 chr22:40951437-40951937 1.32e-01 24_[-10(9.67e-05)]_54 chr8:142717957-142718457 3.10e-03 43_[-1(3.58e-06)]_8_[-1(1.46e-06)]_\ 25 chr10:74826043-74826543 1.84e-04 41_[+7(1.01e-06)]_43 chr16:11915835-11916335 1.13e-02 71_[-6(4.61e-05)]_7 chr11:67507644-67508144 5.22e-06 24_[+8(3.52e-13)]_45 chr5:40835040-40835540 3.96e-01 100 chr17:74203423-74203923 1.11e-01 31_[-1(8.66e-05)]_57 chr12:65606289-65606789 2.18e-02 100 chr16:15590832-15591332 2.15e-01 100 chr19:58519640-58520140 3.69e-01 41_[+1(2.65e-05)]_47 chr21:25734806-25735306 3.97e-02 69_[+1(1.15e-05)]_19 chr17:42773190-42773690 2.10e-01 36_[-1(2.65e-05)]_10_[+1(1.60e-05)]_\ 30 chr10:22552767-22553267 1.87e-03 37_[+1(9.30e-05)]_20_[+7(6.15e-05)]_\ 15 chr1:197201319-197201819 5.39e-01 100 chr19:38374290-38374790 2.19e-02 61_[+1(1.28e-05)]_27 chr10:77287683-77288183 1.60e-01 100 chr16:1308127-1308627 1.32e-02 26_[+7(3.55e-07)]_4_[+7(8.24e-08)]_\ 4_[+7(1.35e-07)]_[+7(1.35e-07)]_2 chr1:52955545-52956045 1.40e-02 100 chr14:67359649-67360149 9.91e-03 9_[+1(1.46e-06)]_79 chr6:136289492-136289992 2.46e-01 100 chr5:181215948-181216448 4.11e-18 3_[-4(4.77e-05)]_5_[+2(1.85e-17)]_2_\ [+3(2.16e-12)]_5 chr6:169751388-169751888 3.98e-01 57_[-1(7.80e-06)]_31 chr19:11344489-11344989 8.43e-02 24_[+6(4.37e-05)]_54 chr12:122266259-12226675 4.57e-02 65_[-1(4.25e-05)]_23 chr7:77122175-77122675 4.84e-04 53_[-6(9.09e-10)]_25 chr17:17958284-17958784 9.10e-02 100 chr1:155262143-155262643 6.92e-01 100 chr1:223992386-223992886 8.79e-01 100 chr6:30557068-30557568 9.29e-02 [-1(9.30e-05)]_88 chr11:119018113-11901861 7.24e-02 76_[+1(1.99e-05)]_12 chr1:150628939-150629439 3.13e-01 100 chr1:229221371-229221871 2.30e-02 10_[-9(3.73e-05)]_42 chr6:21953894-21954394 2.25e-02 100 chr7:129054784-129055284 4.15e-01 100 chr15:70892256-70892756 1.62e-01 100 chr1:156282725-156283225 2.23e-01 2_[+5(4.22e-05)]_67 chr7:128476546-128477046 2.68e-01 [+1(8.03e-05)]_88 chr14:80941611-80942111 6.21e-04 44_[-6(4.27e-10)]_34 chr17:81253449-81253949 4.10e-01 100 chr18:24426289-24426789 1.64e-01 100 chr4:82373861-82374361 4.18e-04 1_[-10(4.17e-06)]_34_[-7(9.62e-05)]_\ 27 chr1:85274835-85275335 2.45e-01 100 chr22:19479290-19479790 1.75e-02 39_[+10(1.56e-05)]_39 chr12:119667676-11966817 2.73e-01 76_[-1(2.65e-05)]_12 chr19:48588610-48589110 7.30e-01 100 chr5:146182503-146183003 1.06e-02 27_[-6(3.96e-08)]_51 chr1:234723902-234724402 6.43e-05 11_[+7(1.86e-10)]_4_[+7(4.25e-07)]_\ 19_[+7(1.23e-08)]_18 chr17:1463107-1463607 1.14e-03 48_[+1(3.55e-05)]_[+1(8.66e-05)]_28 chr10:75613677-75614177 1.43e-01 100 chr16:25049544-25050044 1.14e-03 59_[+10(2.75e-07)]_19 chr1:226944558-226945058 2.17e-08 11_[+7(2.34e-09)]_[-10(2.57e-06)]_\ 21_[+1(3.87e-05)]_18 chr12:113221145-11322164 3.30e-01 50_[-3(4.18e-05)]_28 chr19:58499269-58499769 7.80e-01 18_[-1(6.38e-05)]_70 chr1:827203-827703 7.79e-01 100 chr17:1258901-1259401 6.95e-14 23_[-4(2.89e-07)]_6_[+2(3.02e-19)]_\ 8 chr19:40090632-40091132 2.72e-01 100 chr6:89829609-89830109 3.05e-01 100 chr5:91383336-91383836 8.17e-01 100 chr10:5853639-5854139 1.54e-15 24_[-3(5.47e-11)]_2_[-2(1.83e-18)]_\ 20 chr16:1782556-1783056 4.19e-01 100 chr19:17337114-17337614 1.57e-01 100 chr19:14571811-14572311 2.24e-01 70_[+1(1.76e-05)]_18 chr1:63523140-63523640 3.09e-01 100 chr1:28088353-28088853 1.34e-01 83_[-1(5.13e-07)]_5 chr1:150321317-150321817 3.88e-02 19_[+1(1.45e-05)]_69 chr1:155244578-155245078 3.48e-03 6_[+7(2.47e-08)]_20_[+7(2.05e-08)]_\ 14_[+7(8.12e-10)]_12 chr19:39445317-39445817 8.58e-01 100 chr6:27495576-27496076 1.35e-01 100 chr10:75379137-75379637 3.83e-01 100 chr19:44164671-44165171 2.91e-05 14_[+6(6.63e-10)]_64 chr6:127343088-127343588 9.00e-03 22_[+5(7.88e-05)]_47 chr16:690202-690702 4.88e-02 13_[-1(8.03e-05)]_2_[-7(9.62e-05)]_\ 41_[+1(8.66e-05)]_4 chr1:163321558-163322058 7.39e-01 100 chr11:2400275-2400775 2.51e-01 17_[+1(7.44e-05)]_38_[+1(6.38e-05)]_\ 21 chr6:31958779-31959279 6.10e-01 100 chr14:20461431-20461931 9.77e-01 100 chr1:40257882-40258382 1.79e-01 47_[+7(5.53e-05)]_37 chr21:46286062-46286562 2.36e-01 13_[+1(8.55e-07)]_75 chr16:71808709-71809209 1.61e-01 24_[-7(1.00e-04)]_60 chr14:21511156-21511656 2.32e-02 14_[+1(1.15e-05)]_74 chr1:1375104-1375604 3.74e-01 24_[+1(4.25e-05)]_64 chr3:17730375-17730875 2.99e-01 78_[+10(3.46e-05)] chr6:90587028-90587528 4.42e-01 100 chr8:37302631-37303131 1.10e-01 100 chr1:80403305-80403805 8.83e-02 100 chr11:93783967-93784467 3.72e-05 1_[-7(1.61e-08)]_19_[-1(1.45e-05)]_\ 21_[-1(1.99e-05)]_19 chr16:84186779-84187279 1.29e-02 61_[+1(5.91e-06)]_[-1(3.88e-07)]_15 chr7:133492160-133492660 3.38e-02 100 chr5:150449660-150450160 1.62e-01 29_[+7(1.69e-06)]_55 chr7:151842352-151842852 1.01e-01 52_[-5(8.30e-05)]_17 chr2:201071700-201072200 9.40e-01 100 chr3:9952344-9952844 2.10e-02 59_[-8(6.33e-05)]_10 chr3:15098912-15099412 2.34e-01 61_[-1(5.91e-06)]_27 chr11:61792430-61792930 1.12e-03 30_[+6(1.54e-08)]_48 chr7:108569513-108570013 5.57e-03 [+1(9.30e-05)]_32_[-1(1.02e-05)]_44 chr16:2047673-2048173 1.32e-05 42_[-6(2.23e-11)]_36 chr18:49460605-49461105 6.85e-17 34_[-5(9.56e-18)]_[-3(9.37e-11)]_13 chr7:130440790-130441290 3.21e-01 100 chr5:173144665-173145165 5.12e-01 100 chr11:118251992-11825249 4.07e-01 100 chr1:169367868-169368368 6.23e-02 72_[+6(2.90e-05)]_6 chr17:59707369-59707869 1.46e-02 64_[-1(3.88e-07)]_8_[+1(5.44e-05)]_\ 4 chr6:36874590-36875090 8.96e-02 19_[+1(4.25e-05)]_29_[+1(3.88e-07)]_\ 28 chr12:53501261-53501761 7.03e-01 100 chr19:35248559-35249059 1.25e-01 100 chr12:51172704-51173204 4.62e-05 15_[+1(4.37e-06)]_73 chr16:1420557-1421057 4.42e-01 28_[-1(1.28e-05)]_60 chr2:24076212-24076712 4.69e-03 28_[-2(4.02e-05)]_4_[+1(4.37e-06)]_\ 24 chr1:230978766-230979266 1.05e-06 35_[-6(1.35e-09)]_12_[+1(8.88e-06)]_\ 19 chr5:59303215-59303715 1.24e-01 [-10(8.39e-05)]_78 chr6:82260138-82260638 1.53e-01 100 chr16:30571838-30572338 3.69e-01 100 chr12:806374-806874 7.37e-02 52_[-10(9.34e-05)]_26 chr1:224330205-224330705 7.48e-01 100 chr3:48439898-48440398 8.66e-01 100 chr16:2682197-2682697 1.09e-01 9_[-1(4.25e-05)]_79 chr1:20732198-20732698 9.67e-01 100 chr19:17932753-17933253 5.78e-01 100 chr14:44961891-44962391 6.90e-04 5_[-6(5.08e-09)]_12_[+1(2.93e-05)]_\ 49 chr17:57849799-57850299 1.10e-01 49_[-1(6.50e-07)]_39 chr1:167936275-167936775 2.24e-01 67_[+2(9.07e-05)]_1 chr19:12681637-12682137 3.10e-02 25_[-1(9.30e-05)]_20_[-1(2.08e-06)]_\ 31 chr5:81301369-81301869 3.76e-01 23_[+1(2.68e-06)]_65 chr1:43389617-43390117 1.72e-03 57_[+1(1.46e-06)]_31 chr1:100132760-100133260 1.21e-01 34_[+1(5.19e-06)]_54 chr5:159263006-159263506 1.16e-02 45_[+1(5.71e-08)]_6_[+1(3.23e-05)]_\ 7_[+1(8.55e-07)]_6 chr12:38316440-38316940 6.53e-02 100 chr12:6663085-6663585 4.32e-01 100 chr12:34022154-34022654 1.76e-01 100 chr19:36666555-36667055 2.52e-02 71_[-1(1.02e-05)]_17 chr7:5822859-5823359 3.49e-08 45_[-1(1.02e-05)]_11_[+6(1.49e-09)]_\ 10 chr3:14651489-14651989 2.25e-02 61_[+1(3.88e-07)]_27 chr19:39435664-39436164 1.51e-01 72_[-1(1.99e-05)]_16 chr5:149345136-149345636 6.07e-02 12_[-1(1.15e-05)]_48_[-1(3.16e-06)]_\ 16 chr1:154182976-154183476 1.61e-05 2_[-7(1.40e-05)]_22_[-1(7.44e-05)]_\ 21_[+3(6.31e-09)]_5 chr14:90383121-90383621 3.19e-01 100 chr19:43950898-43951398 3.85e-02 80_[+1(4.37e-06)]_8 chr5:37371026-37371526 2.67e-05 7_[-4(5.48e-05)]_22_[+7(6.68e-07)]_\ 24 chr1:156740987-156741487 1.09e-01 35_[-1(5.44e-05)]_22_[-1(6.38e-05)]_\ 19 chr15:55196721-55197221 5.81e-02 32_[-1(2.65e-05)]_18_[-1(3.87e-05)]_\ 26 chr7:102748618-102749118 4.00e-05 66_[+6(1.23e-09)]_12 chr19:44259548-44260048 8.57e-11 10_[+5(2.38e-16)]_2_[-8(9.51e-05)]_\ 26 chr1:150293606-150294106 1.52e-01 41_[+1(1.15e-05)]_6_[+1(7.44e-05)]_\ 29 chr8:143281438-143281938 1.79e-03 36_[-1(3.58e-06)]_8_[-1(1.46e-06)]_\ 32 chr12:48105899-48106399 1.29e-02 19_[-1(1.15e-05)]_19_[-3(9.59e-06)]_\ 28 chr12:49567884-49568384 3.46e-01 47_[+1(5.19e-06)]_21_[+1(2.68e-06)]_\ 8 chr7:93232066-93232566 4.96e-04 40_[-6(4.27e-10)]_38 chr19:38849854-38850354 9.92e-01 100 chr17:42154862-42155362 4.47e-01 100 chr1:155934240-155934740 1.25e-01 16_[+1(6.79e-06)]_72 chr16:30650436-30650936 3.45e-02 22_[-1(5.91e-05)]_66 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (10) found. ******************************************************************************** CPU: wotan ********************************************************************************