# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 ATGAAAGACATRAATCYAC MEME-1 ATGAAAGACATRAATCYAC 4.0e-340 5.3e-343 -788.11 0.0 50 482 448 533 0.10373 2.2e-345 240 1 GRGTTYDYTGAGCTTCTTGRAT MEME-2 GRGTTYDYTGAGCTTCTTGRAT 1.5e-174 2.0e-177 -406.85 0.0 91 479 356 430 0.18998 8.5e-180 239 1 WTTTGGRAARTTTTYAGCCAT MEME-3 WTTTGGRAARTTTTYAGCCAT 1.4e-142 1.8e-145 -333.29 0.0 88 480 351 486 0.18333 7.5e-148 239 1 TATTTCTTCAAATATT MEME-4 TATTTCTTCAAATATT 9.0e-052 1.2e-054 -124.17 0.0 133 485 294 469 0.27423 4.9e-057 242 1 TTTYTTTGTRTTTATYCTRCTT MEME-5 TTTYTTTGTRTTTATYCTRCTT 7.4e-069 9.8e-072 -163.50 0.0 131 479 357 552 0.27349 4.1e-074 239 1 TGAAAGACATRMATMYACANAT MEME-6 TGAAAGACATRMATMYACANAT 6.3e-349 8.3e-352 -808.40 0.0 53 479 477 568 0.11065 3.5e-354 239 1 CARCCAYACAAACAAGYCWRCATAATAACCAGCTAACAACAYR MEME-7 CARCCAYACAAACAAGYCWRCATAATAACCAGCTAACAACAYR 5.5e-005 7.2e-008 -16.44 0.0 74 458 12 12 0.16157 3.2e-010 228 1 RRAGARAGAAARRGRSAGARAV MEME-8 RRAGARAGAAARRGRSAGARAV 6.0e-009 7.9e-012 -25.57 0.0 331 479 426 509 0.69102 3.3e-014 239 1 TGAGCTTCTTGGATST MEME-9 TGAGCTTCTTGGATST 2.6e-155 3.5e-158 -362.57 0.0 85 485 343 455 0.17526 1.4e-160 242 1 AATAAATAAATAAATAAATA MEME-10 AATAAATAAATAAATAAATA 3.2e-003 4.3e-006 -12.37 0.0 33 481 13 27 0.06861 1.8e-008 240 2 AAAGAYAT DREME-1 AAAGACAT 4.7e-153 6.1e-156 -357.39 0.0 47 493 225 307 0.09533 2.5e-158 246 2 ATYTGTR DREME-2 ATYTGTR 1.7e-097 2.2e-100 -229.45 0.0 62 494 217 355 0.12551 9.1e-103 246 2 CAAGHAG DREME-3 CAAGAAG 3.2e-052 4.2e-055 -125.21 0.0 104 494 188 291 0.21053 1.7e-057 246 2 AAWTTTGG DREME-4 AAATTTGG 7.6e-053 1.0e-055 -126.64 0.0 71 493 107 144 0.14402 4.1e-058 246 2 ATRTGTRG DREME-5 ATRTGTAG 9.7e-046 1.3e-048 -110.27 0.0 55 493 82 115 0.11156 5.2e-051 246 2 ATTATYTC DREME-6 ATTATTTC 1.0e-029 1.3e-032 -73.38 0.0 123 493 113 157 0.24949 5.5e-035 246 2 TATTTGAA DREME-7 TATTTGAA 4.6e-021 6.1e-024 -53.46 0.0 113 493 82 118 0.22921 2.5e-026 246 2 ATGAMAGR DREME-8 ATGAMAGR 1.5e-166 1.9e-169 -388.47 0.0 51 493 245 318 0.10345 7.9e-172 246 2 AAAACTYC DREME-9 AAAACTTC 8.4e-016 1.1e-018 -41.35 0.0 89 493 56 88 0.18053 4.5e-021 246 2 ATAAACHC DREME-10 ATAAACTC 1.8e-022 2.3e-025 -56.71 0.0 135 493 89 116 0.27383 9.5e-028 246 2 GAADCTCA DREME-11 GAADCTCA 2.6e-041 3.4e-044 -100.10 0.0 115 493 105 124 0.23327 1.4e-046 246 2 AATRGCTG DREME-12 AATGGCTG 3.2e-006 4.3e-009 -19.27 0.0 105 493 74 166 0.21298 1.7e-011 246 2 AACTGATG DREME-13 AACTGATG 1.4e-012 1.8e-015 -33.92 0.0 57 493 88 287 0.11562 7.5e-018 246 2 AACTCYAA DREME-14 AACTCYAA 1.5e-026 2.0e-029 -66.09 0.0 107 493 71 88 0.21704 8.0e-032 246 2 GGCCAARA DREME-15 GGCCAARA 8.3e0000 1.1e-002 -4.51 0.0 107 493 116 380 0.21704 4.5e-005 246 3 M0108_1.02 (ARID5A)_(Mus_musculus)_(DBD_0.97) NDWAATATTKN 8.2e-002 1.1e-004 -9.13 0.0 126 490 187 527 0.25714 4.4e-007 244 3 M0177_1.02 (TWIST2)_(Mus_musculus)_(DBD_1.00) NMCATATGTN 1.2e0000 1.5e-003 -6.49 0.0 301 491 365 517 0.61303 6.2e-006 245 3 M0437_1.02 (ZNF32)_(Mus_musculus)_(DBD_0.99) TATRTATRT 2.1e-008 2.8e-011 -24.30 0.0 234 492 208 304 0.47561 1.1e-013 245 3 M0633_1.02 DMRT2 KAATKTATWN 6.4e0000 8.4e-003 -4.78 0.0 137 491 202 566 0.27902 3.4e-005 245 3 M0747_1.02 (FOXL2)_(Mus_musculus)_(DBD_0.70) WNNRTAAAYA 2.3e-001 3.0e-004 -8.12 0.0 123 491 201 594 0.25051 1.2e-006 245 3 M0892_1.02 EMX1 NYTAATKAVN 1.4e-003 1.9e-006 -13.18 0.0 107 491 181 561 0.21792 7.7e-009 245 3 M0905_1.02 (HOXA4)_(Mus_musculus)_(DBD_1.00) HTAATKRNN 4.0e-005 5.2e-008 -16.77 0.0 96 492 150 473 0.19512 2.1e-010 245 3 M0949_1.02 (AC012531.1)_(Mus_musculus)_(DBD_1.00) NTAATDR 1.4e-003 1.9e-006 -13.19 0.0 92 494 116 377 0.18623 7.6e-009 246 3 M0999_1.02 (NKX6-1)_(Mus_musculus)_(DBD_1.00) NWTAATKRN 1.0e-011 1.4e-014 -31.93 0.0 108 492 210 560 0.21951 5.5e-017 245 3 M1012_1.02 (HOXB4)_(Mus_musculus)_(DBD_1.00) NTAATKRNN 2.6e-008 3.4e-011 -24.11 0.0 96 492 168 503 0.19512 1.4e-013 245 3 M1025_1.02 (HOXD1)_(Mus_musculus)_(DBD_0.98) NNYVATTA 1.7e-005 2.2e-008 -17.61 0.0 113 493 129 335 0.22921 9.1e-011 246 3 M1027_1.02 (HOXA6)_(Mus_musculus)_(DBD_1.00) WTAATKRBN 3.1e-007 4.1e-010 -21.61 0.0 96 492 164 499 0.19512 1.7e-012 245 3 M1070_1.02 (HOXC5)_(Mus_musculus)_(DBD_1.00) NTAATKRNN 1.5e-007 2.0e-010 -22.31 0.0 96 492 158 472 0.19512 8.3e-013 245 3 M1071_1.02 (HOXD3)_(Mus_musculus)_(DBD_1.00) NTAATKRN 2.0e-006 2.7e-009 -19.75 0.0 97 493 168 524 0.19675 1.1e-011 246 3 M1073_1.02 (HOXA3)_(Mus_musculus)_(DBD_1.00) HTAATKRNN 1.4e-006 1.8e-009 -20.14 0.0 96 492 181 577 0.19512 7.3e-012 245 3 M1163_1.02 (NKX6-3)_(PBM_CONSTRUCTS)_(DBD_1.00) NWTAATKRN 3.4e-006 4.5e-009 -19.22 0.0 98 492 165 508 0.19919 1.8e-011 245 3 M1507_1.02 (LCOR)_(Meleagris_gallopavo)_(DBD_1.00) NDWTTNGGNN 3.4e-015 4.4e-018 -39.96 0.0 71 491 170 577 0.14460 1.8e-020 245 3 M1582_1.02 (HMG20B)_(Mus_musculus)_(DBD_0.94) NWAWATAATWW 2.3e0000 3.1e-003 -5.79 0.0 420 490 483 526 0.85714 1.3e-005 244 3 M1583_1.02 (BBX)_(Mus_musculus)_(DBD_0.99) TTCATTGA 1.0e-002 1.4e-005 -11.21 0.0 83 493 101 359 0.16836 5.5e-008 246 3 M1605_1.02 (SOX1)_(Mus_musculus)_(DBD_1.00) ATTSWHNNNN 3.4e-012 4.5e-015 -33.03 0.0 41 491 113 572 0.08350 1.9e-017 245 3 M1950_1.02 ZNF354C GTGGAK 6.5e-005 8.6e-008 -16.27 0.0 43 495 97 580 0.08687 3.5e-010 247 3 M1955_1.02 STAT1 TTTCYRGGAAA 2.3e-003 3.0e-006 -12.73 0.0 72 490 124 514 0.14694 1.2e-008 244 3 M2281_1.02 FOXH1 BNSAATCCACA 1.8e-036 2.4e-039 -88.92 0.0 48 490 170 560 0.09796 9.9e-042 244 3 M2287_1.02 (HOXC9)_(Mus_musculus)_(DBD_0.98) RGCMATAAATCAB 7.3e-023 9.6e-026 -57.61 0.0 34 488 115 525 0.06967 3.9e-028 243 3 M2306_1.02 POU2F2 HDNATTTGCATRW 3.7e-003 4.9e-006 -12.23 0.0 34 488 74 531 0.06967 2.0e-008 243 3 M2307_1.02 PRDM1 DRAAAGTGAAAGTRA 1.0e0000 1.3e-003 -6.63 0.0 304 486 417 585 0.62551 5.5e-006 242 3 M2310_1.02 RUNX2 MAAACCACARAMMMM 4.1e-005 5.4e-008 -16.74 0.0 40 486 95 586 0.08230 2.2e-010 242 3 M2319_1.02 TCF7L2 TBYCTTTGAWSTYN 3.3e-015 4.3e-018 -39.99 0.0 35 487 111 590 0.07187 1.8e-020 243 3 M2321_1.02 TP63 DDRCAWGYHCARRCWTGYHY 1.8e-005 2.3e-008 -17.58 0.0 53 481 96 444 0.11019 9.7e-011 240 3 M4461_1.02 ETS1 GCMTBCTGGGARWTGTAGTYY 2.9e-035 3.8e-038 -86.17 0.0 60 480 136 321 0.12500 1.6e-040 239 3 M4477_1.02 SRF NHATGNCCAWAWAAGGMMA 2.0e-004 2.6e-007 -15.17 0.0 68 482 114 461 0.14108 1.1e-009 240 3 M4484_1.02 ZNF143 CTGGGARTTGTAGTY 2.7e-036 3.6e-039 -88.51 0.0 60 486 157 404 0.12346 1.5e-041 242 3 M4527_1.02 SMARCC2 RRACTACAAYTCCCAGVAKGC 1.1e-029 1.5e-032 -73.30 0.0 60 480 120 289 0.12500 6.1e-035 239 3 M4545_1.02 ZNF683 DRAAAGTGAAAGTKR 5.7e0000 7.5e-003 -4.89 0.0 224 486 318 584 0.46091 3.1e-005 242 3 M4665_1.02 GATA3 VWGATARVMATCWSY 9.9e-021 1.3e-023 -52.70 0.0 38 486 118 518 0.07819 5.4e-026 242 3 M4692_1.02 SIX5 ACTACAAYTC 2.5e-008 3.3e-011 -24.13 0.0 51 491 103 462 0.10387 1.3e-013 245 3 M4708_1.02 TBP TATGCAAATA 3.7e-001 4.9e-004 -7.62 0.0 191 491 277 570 0.38900 2.0e-006 245 3 M4840_1.02 (FEZF1)_(Drosophila_melanogaster)_(DBD_0.91) AAAWGMGCAWC 3.8e0000 5.1e-003 -5.28 0.0 356 490 462 576 0.72653 2.1e-005 244 3 M5291_1.02 ARX YTAATTHRATTAN 6.0e-006 7.9e-009 -18.65 0.0 30 488 69 472 0.06148 3.3e-011 243 3 M5292_1.02 ATF4 RKATGAYGCAATM 2.1e-002 2.8e-005 -10.48 0.0 38 488 69 457 0.07787 1.2e-007 243 3 M5310_1.02 BSX NTAATBRS 1.0e-002 1.3e-005 -11.23 0.0 237 493 326 548 0.48073 5.4e-008 246 3 M5335_1.02 CUX2 ATCGATAWNWTTATYGAT 4.4e-007 5.8e-010 -21.28 0.0 75 483 51 121 0.15528 2.4e-012 241 3 M5460_1.02 FOXL1 RTAAACA 2.9e-001 3.9e-004 -7.86 0.0 126 494 199 582 0.25506 1.6e-006 246 3 M5502_1.02 GSX1 NBTAATKRSN 2.0e0000 2.6e-003 -5.95 0.0 387 491 485 564 0.78819 1.1e-005 245 3 M5542_1.02 HOXB3 NYTAATKRNN 8.5e0000 1.1e-002 -4.49 0.0 107 491 166 574 0.21792 4.6e-005 245 3 M5544_1.02 HOXC10 DTTTWATKDB 6.2e-003 8.2e-006 -11.71 0.0 23 491 59 580 0.04684 3.3e-008 245 3 M5547_1.02 HOXC11 DRTCRTWAAAH 3.9e-004 5.2e-007 -14.47 0.0 56 490 103 498 0.11429 2.1e-009 244 3 M5555_1.02 HOXD11 RTCGTAAAAH 1.6e0000 2.1e-003 -6.18 0.0 245 491 287 480 0.49898 8.5e-006 245 3 M5567_1.02 HSF4 GAANVTTCTAGAA 5.9e-003 7.8e-006 -11.76 0.0 78 488 127 497 0.15984 3.2e-008 243 3 M5624_1.02 MEOX2 DSTAATTAWN 2.4e-001 3.1e-004 -8.07 0.0 79 491 136 570 0.16090 1.3e-006 245 3 M5729_1.02 POU2F3 ATTWGCATA 1.7e-003 2.2e-006 -13.02 0.0 238 492 340 564 0.48374 9.0e-009 245 3 M5735_1.02 POU3F3 WAATTWGCATAWW 8.2e-002 1.1e-004 -9.13 0.0 238 488 317 532 0.48770 4.5e-007 243 3 M5738_1.02 POU3F4 ATTWGCATA 4.3e-003 5.7e-006 -12.08 0.0 200 492 276 526 0.40650 2.3e-008 245 3 M5740_1.02 POU4F1 ATGMATAATTAATG 2.9e-007 3.8e-010 -21.68 0.0 99 487 174 519 0.20329 1.6e-012 243 3 M5743_1.02 POU4F3 RTGMATWATTAATGAV 5.8e-014 7.7e-017 -37.10 0.0 95 485 185 504 0.19588 3.2e-019 242 3 M5744_1.02 POU5F1B ATTWGCATA 1.1e-002 1.5e-005 -11.11 0.0 238 492 336 564 0.48374 6.1e-008 245 3 M5903_1.02 TCF7L1 AAAGATCAAAGG 3.9e-004 5.2e-007 -14.47 0.0 241 489 344 556 0.49284 2.1e-009 244 3 M5967_1.02 ZNF232 RTGTTAAAYGTAGATTAAG 9.9e0000 1.3e-002 -4.34 0.0 118 482 51 126 0.24481 5.5e-005 240 3 M5976_1.02 ZNF713 TTCGTGGCATTYTTCTA 1.2e-009 1.6e-012 -27.16 0.0 96 484 86 193 0.19835 6.7e-015 241 3 M6114_1.02 FOXA1 WAWGYAAAYA 4.0e0000 5.3e-003 -5.24 0.0 301 491 410 591 0.61303 2.2e-005 245 3 M6159_1.02 BCL6 TTCCWRGAAWGYHHWH 1.0e-004 1.4e-007 -15.82 0.0 83 485 159 582 0.17113 5.6e-010 242 3 M6167_1.02 CDX1 HCATAAAD 1.4e-012 1.8e-015 -33.92 0.0 29 493 94 595 0.05882 7.5e-018 246 3 M6171_1.02 CEBPD RRTKDBGCAAT 7.5e-001 9.9e-004 -6.91 0.0 38 490 78 589 0.07755 4.1e-006 244 3 M6181_1.02 CREM CRVTGACGTCA 1.3e-003 1.7e-006 -13.28 0.0 46 490 87 493 0.09388 7.0e-009 244 3 M6184_1.02 CUX1 RBRSNDATCGATSK 3.0e-002 4.0e-005 -10.13 0.0 35 487 70 508 0.07187 1.6e-007 243 3 M6238_1.02 FOXF1 WAAATAAACAW 6.6e-003 8.7e-006 -11.65 0.0 120 490 200 579 0.24490 3.6e-008 244 3 M6241_1.02 FOXJ2 WAAAYAAAYA 6.6e-003 8.7e-006 -11.65 0.0 111 491 189 583 0.22607 3.6e-008 245 3 M6269_1.02 HBP1 AYYCATTGA 1.8e-003 2.4e-006 -12.93 0.0 76 492 138 559 0.15447 9.9e-009 245 3 M6280_1.02 HMGA2 AATWWYSSSSAATAT 2.0e-020 2.6e-023 -51.99 0.0 80 486 153 399 0.16461 1.1e-025 242 3 M6282_1.02 HNF1B GTTAAWYATTAACY 2.0e-001 2.7e-004 -8.23 0.0 101 487 146 488 0.20739 1.1e-006 243 3 M6287_1.02 HSF2 VGAABRTTCTAGAA 7.6e-003 1.0e-005 -11.50 0.0 79 487 144 575 0.16222 4.2e-008 243 3 M6291_1.02 HOXA1 CATCCATCMA 1.7e-017 2.2e-020 -45.25 0.0 69 491 162 526 0.14053 9.1e-023 245 3 M6292_1.02 HOXA5 CATTAATYAR 4.0e-002 5.2e-005 -9.86 0.0 29 491 61 512 0.05906 2.1e-007 245 3 M6296_1.02 HOXB6 KKCATMAATCAWT 1.3e-006 1.7e-009 -20.17 0.0 78 488 121 412 0.15984 7.2e-012 243 3 M6297_1.02 HOXB7 MATYAATCAA 1.8e-008 2.4e-011 -24.46 0.0 121 491 187 463 0.24644 9.8e-014 245 3 M6298_1.02 HOXB8 BMATTAATCAA 1.7e-015 2.3e-018 -40.63 0.0 78 490 156 466 0.15918 9.3e-021 244 3 M6299_1.02 HOXC6 AAAGTAATAAATCAT 8.9e-035 1.2e-037 -85.03 0.0 48 486 137 401 0.09877 4.9e-040 242 3 M6300_1.02 HOXC8 GSBHATYAATSAAR 9.2e0000 1.2e-002 -4.41 0.0 91 487 138 540 0.18686 5.0e-005 243 3 M6304_1.02 HOXD9 HMATNAAWYT 1.4e-050 1.9e-053 -121.42 0.0 37 491 172 581 0.07536 7.6e-056 245 3 M6309_1.02 IRF3 GGAAAGBGAAASBRRRA 1.2e-002 1.5e-005 -11.08 0.0 346 484 465 573 0.71488 6.4e-008 241 3 M6328_1.02 LHX2 YRSDTTYAATWAG 3.4e0000 4.5e-003 -5.40 0.0 222 488 291 533 0.45492 1.9e-005 243 3 M6329_1.02 LHX3 AAAATTAATTARY 3.5e0000 4.7e-003 -5.37 0.0 94 488 115 415 0.19262 1.9e-005 243 3 M6333_1.02 MAFG HATGACT 3.6e0000 4.8e-003 -5.34 0.0 52 494 92 568 0.10526 1.9e-005 246 3 M6361_1.02 NFATC1 AWGGAAWTTTCCD 4.7e-002 6.2e-005 -9.69 0.0 84 488 121 452 0.17213 2.6e-007 243 3 M6364_1.02 NFATC3 RDTTTTCCA 2.6e-001 3.4e-004 -8.00 0.0 124 492 201 591 0.25203 1.4e-006 245 3 M6368_1.02 NFIL3 VKVMRTTACRTAAY 1.8e-001 2.4e-004 -8.35 0.0 33 487 50 356 0.06776 9.7e-007 243 3 M6380_1.02 NOBOX HTAATTRSY 2.8e-002 3.7e-005 -10.20 0.0 106 492 170 548 0.21545 1.5e-007 245 3 M6384_1.02 NR1H4 AGGTCAHTGACCYY 1.9e0000 2.5e-003 -5.99 0.0 81 487 115 471 0.16632 1.0e-005 243 3 M6385_1.02 NR1I2 VTGAACTYNNTTRACCYHH 7.4e-006 9.7e-009 -18.45 0.0 76 482 151 567 0.15768 4.0e-011 240 3 M6412_1.02 PBX1 VHMATCAATCAAWTH 9.9e-007 1.3e-009 -20.46 0.0 28 486 78 580 0.05761 5.4e-012 242 3 M6416_1.02 CBFB TYTGTGGTYWB 8.7e-007 1.1e-009 -20.59 0.0 56 490 126 591 0.11429 4.7e-012 244 3 M6417_1.02 POU1F1 RWATATTCATKAR 6.7e-016 8.9e-019 -41.57 0.0 68 488 171 590 0.13934 3.6e-021 243 3 M6418_1.02 PITX2 DBTAATCCMA 9.4e-003 1.2e-005 -11.30 0.0 41 491 89 592 0.08350 5.1e-008 245 3 M6426_1.02 POU3F2 CATRAATWWT 2.5e-042 3.3e-045 -102.41 0.0 81 491 244 582 0.16497 1.4e-047 245 3 M6429_1.02 POU6F1 CATAAWTTATGCR 2.6e-003 3.5e-006 -12.57 0.0 86 488 102 339 0.17623 1.4e-008 243 3 M6449_1.02 REL DKGGRNWTTCCV 8.0e-001 1.1e-003 -6.86 0.0 81 489 134 560 0.16564 4.3e-006 244 3 M6457_1.02 RUNX1 WAACCACARW 2.4e-009 3.1e-012 -26.49 0.0 51 491 126 597 0.10387 1.3e-014 245 3 M6459_1.02 RUNX3 AACCRCAAAMMMCV 1.7e-003 2.2e-006 -13.03 0.0 207 487 283 515 0.42505 9.1e-009 243 3 M6470_1.02 SOX10 BCWTTGT 8.1e0000 1.1e-002 -4.54 0.0 416 494 538 599 0.84211 4.4e-005 246 3 M6491_1.02 STAT5A YTTCYVRGAAWT 1.8e-010 2.4e-013 -29.07 0.0 191 489 310 555 0.39059 9.7e-016 244 3 M6492_1.02 STAT5B DTTTCYDGGAATT 5.9e-021 7.8e-024 -53.21 0.0 72 488 172 513 0.14754 3.2e-026 243 3 M6510_1.02 TEF TGTTTATRTAAMTK 5.5e-001 7.3e-004 -7.23 0.0 33 487 68 555 0.06776 3.0e-006 243 3 M6544_1.02 HIVEP1 VGGGATTTCCCA 8.7e0000 1.2e-002 -4.46 0.0 89 489 127 502 0.18200 4.8e-005 244 3 M6555_1.02 ZNF333 BKATAATGA 1.1e-002 1.5e-005 -11.13 0.0 214 492 293 533 0.43496 6.0e-008 245 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).