# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 CWTCMTCMTCATCMTC MEME-1 CWTCMTCMTCATCMTC 1.3e-113 1.7e-116 -266.56 0.0 89 485 366 596 0.18351 7.1e-119 242 1 GATGATGATGAKGAWG MEME-2 GATGATGATGAKGAWG 5.1e-101 6.8e-104 -237.55 0.0 99 485 367 595 0.20412 2.8e-106 242 1 CHTCHTCHTCHTCMTC MEME-3 CHTCHTCHTCHTCMTC 2.8e-102 3.7e-105 -240.47 0.0 89 485 353 599 0.18351 1.5e-107 242 1 RTGRTGATGRTG MEME-4 RTGRTGATGRTG 2.5e-040 3.4e-043 -97.80 0.0 91 489 202 406 0.18609 1.4e-045 244 1 GARGARGARGARGARG MEME-5 GARGARGARGARGARG 3.3e-073 4.4e-076 -173.51 0.0 87 485 256 443 0.17938 1.8e-078 242 1 TGATGRTGA MEME-6 TGATGRTGA 1.9e-029 2.5e-032 -72.76 0.0 86 492 167 371 0.17480 1.0e-034 245 1 YTCYTCYTCYTC MEME-7 YTCYTCYTCYTC 3.2e-055 4.3e-058 -132.10 0.0 79 489 211 412 0.16155 1.8e-060 244 1 AGGARGA MEME-8 AGGARGA 1.5e-047 2.0e-050 -114.43 0.0 92 494 215 411 0.18623 8.1e-053 246 1 AYCAYCA MEME-9 AYCAYCA 4.0e-019 5.3e-022 -48.99 0.0 94 494 162 390 0.19028 2.2e-024 246 2 ABCACCAT DREME-1 ATCACCAT 9.0e-004 1.2e-006 -13.64 0.0 165 493 126 245 0.33469 4.9e-009 246 2 GAWGARGA DREME-2 GAAGARGA 5.3e-059 7.1e-062 -140.80 0.0 89 493 226 408 0.18053 2.9e-064 246 2 CCTCSTCC DREME-3 CCTCCTCC 3.2e-043 4.3e-046 -104.46 0.0 103 493 170 276 0.20892 1.8e-048 246 2 ACYRTCAT DREME-4 ACCATCAT 1.5e-004 2.0e-007 -15.44 0.0 59 493 65 246 0.11968 8.0e-010 246 2 AMGATGAT DREME-8 AMGATGAT 2.6e-021 3.4e-024 -54.03 0.0 71 493 94 206 0.14402 1.4e-026 246 3 M0714_1.02 (ENSG00000235187)_(Mus_musculus)_(DBD_1.00) NDBMGGAWRY 1.8e-001 2.4e-004 -8.35 0.0 67 491 114 538 0.13646 9.7e-007 245 3 M1906_1.02 SP1 RGGGGMGGGGC 6.4e-002 8.5e-005 -9.38 0.0 86 490 131 490 0.17551 3.5e-007 244 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 5.8e-022 7.6e-025 -55.53 0.0 74 488 169 482 0.15164 3.1e-027 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 9.7e-010 1.3e-012 -27.38 0.0 78 490 149 498 0.15918 5.3e-015 244 3 M2314_1.02 SP2 SSVVRGRGGCGGGRC 5.5e-005 7.3e-008 -16.44 0.0 86 486 136 459 0.17695 3.0e-010 242 3 M2390_1.02 EHF SAGGAAGK 4.3e-017 5.8e-020 -44.30 0.0 81 493 171 498 0.16430 2.3e-022 246 3 M4453_1.02 BCL11A ADGRGGAASTGAAAV 6.0e-011 8.0e-014 -30.16 0.0 80 486 162 528 0.16461 3.3e-016 242 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 9.3e-036 1.2e-038 -87.28 0.0 72 480 206 528 0.15000 5.2e-041 239 3 M5425_1.02 ETV6 CCGGAASCGGAAGYR 1.4e-014 1.8e-017 -38.54 0.0 82 486 133 360 0.16872 7.5e-020 242 3 M5865_1.02 SPIC NAAAAGVGGAAGTA 3.6e-020 4.8e-023 -51.38 0.0 85 487 186 504 0.17454 2.0e-025 243 3 M6119_1.02 SPI1 RAAAAGAGGAAGTGV 1.9e-031 2.6e-034 -77.34 0.0 90 486 208 474 0.18519 1.1e-036 242 3 M6123_1.02 (ZNF281)_(Mus_musculus)_(DBD_1.00) GRGKTGGGGGAGGGG 1.0e-005 1.4e-008 -18.12 0.0 130 486 212 533 0.26749 5.6e-011 242 3 M6154_1.02 ATF5 TAAGGRAGARGK 1.2e-018 1.5e-021 -47.93 0.0 85 489 205 594 0.17382 6.3e-024 244 3 M6204_1.02 ELF2 TDNCAGGAAGTRRVT 6.2e-005 8.2e-008 -16.31 0.0 98 486 149 459 0.20165 3.4e-010 242 3 M6206_1.02 ELF5 AHMAGGAWRTW 6.0e-002 8.0e-005 -9.43 0.0 86 490 144 553 0.17551 3.3e-007 244 3 M6221_1.02 ETS2 VMVGGAAGTKS 7.9e-001 1.1e-003 -6.86 0.0 118 490 173 530 0.24082 4.3e-006 244 3 M6222_1.02 ETV4 SAGGAAGY 1.7e0000 2.3e-003 -6.08 0.0 77 493 124 545 0.15619 9.3e-006 246 3 M6336_1.02 MAZ RGGGDRGGGAGGGRGGG 1.5e-003 2.0e-006 -13.11 0.0 44 484 90 531 0.09091 8.4e-009 241 3 M6338_1.02 NR3C2 YMCHWCAACCWGKHCTD 1.7e-018 2.3e-021 -47.53 0.0 80 484 198 594 0.16529 9.4e-024 241 3 M6482_1.02 SP3 VGVVGGGGGCGGGGCBRGSS 1.7e0000 2.2e-003 -6.10 0.0 87 481 124 475 0.18087 9.4e-006 240 3 M6485_1.02 SPIB ARAAASMGGAAS 5.1e-016 6.7e-019 -41.84 0.0 65 489 148 501 0.13292 2.8e-021 244 3 M6510_1.02 TEF TGTTTATRTAAMTK 5.1e0000 6.8e-003 -4.99 0.0 49 487 79 497 0.10062 2.8e-005 243 3 M6535_1.02 WT1 GMGGGGGCGKGGG 1.1e-003 1.4e-006 -13.48 0.0 126 488 184 489 0.25820 5.8e-009 243 3 M6539_1.02 ZBTB7B CGGVGRRGGGGMGSRGGSGGGH 4.0e-006 5.3e-009 -19.05 0.0 67 479 105 391 0.13987 2.2e-011 239 3 M6540_1.02 ZBTB4 CAATRGYGDTDGYGR 2.8e-001 3.7e-004 -7.91 0.0 122 486 187 548 0.25103 1.5e-006 242 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).