# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 GGATTYTGTTATATTCCTYT MEME-1 GGATTYTGTTATATTCCTYT 1.5e-131 1.9e-134 -307.89 0.0 69 481 242 314 0.14345 8.0e-137 240 1 CYTGGCAMRSTGCCAR MEME-2 CYTGGCAMRSTGCCAR 5.7e-038 7.6e-041 -92.38 0.0 53 485 83 139 0.10928 3.1e-043 242 1 GACATTGTGAATGWTATRTTG MEME-3 GACATTGTGAATGWTATRTTG 1.3e-054 1.7e-057 -130.72 0.0 72 480 174 320 0.15000 7.1e-060 239 1 ARAAHAAAAWYCAACACTCTTY MEME-4 ARAAHAAAAWYCAACACTCTTY 4.6e-033 6.1e-036 -81.09 0.0 111 479 211 396 0.23173 2.5e-038 239 1 ARGAATATAACARAATCCAGA MEME-5 ARGAATATAACARAATCCAGA 2.9e-150 3.9e-153 -350.95 0.0 90 480 263 291 0.18750 1.6e-155 239 1 CCCTTATCYWCAACYGCATAAGACAGACACTCCCAGAGCGGCC MEME-7 CCCTTATCYWCAACYGCATAAGACAGACACTCCCAGAGCGGCC 1.4e-007 1.9e-010 -22.39 0.0 76 458 17 18 0.16594 8.3e-013 228 1 WKYGMSTGCACTCMRAMCCWGCKGAKT MEME-8 WKYGMSTGCACTCMRAMCCWGCKGAKT 2.5e-011 3.3e-014 -31.03 0.0 86 474 27 31 0.18143 1.4e-016 236 1 TTTKDATTGTATSCTG MEME-9 TTTKDATTGTATSCTG 3.6e-026 4.7e-029 -65.22 0.0 107 485 183 366 0.22062 2.0e-031 242 1 GACTRGAGAGACCACKRGGTGRAAHAGGRGG MEME-10 GACTRGAGAGACCACKRGGTGRAAHAGGRGG 1.3e-004 1.7e-007 -15.59 0.0 126 470 18 19 0.26809 7.3e-010 234 2 CTGGRTTY DREME-1 CTGGATTY 1.5e-069 2.0e-072 -165.09 0.0 71 493 139 189 0.14402 8.1e-075 246 2 AAKAYAAC DREME-2 AAKATAAC 1.7e-045 2.2e-048 -109.73 0.0 71 493 103 151 0.14402 9.0e-051 246 2 CTYTRAA DREME-3 CTYTRAA 3.1e-011 4.1e-014 -30.83 0.0 94 494 122 312 0.19028 1.7e-016 246 2 ACAATRTM DREME-4 ACAATGTM 1.5e-028 1.9e-031 -70.71 0.0 85 493 78 113 0.17241 7.9e-034 246 2 GTGCCAR DREME-5 GTGCCAR 5.9e-013 7.9e-016 -34.78 0.0 78 494 52 94 0.15789 3.2e-018 246 2 AYACTC DREME-6 AYACTC 8.4e-015 1.1e-017 -39.04 0.0 91 495 115 270 0.18384 4.5e-020 247 2 GAACAWA DREME-7 GAACAWA 1.5e-003 1.9e-006 -13.15 0.0 88 494 62 171 0.17814 7.9e-009 246 2 GTRGAGA DREME-9 GTRGAGA 1.1e-001 1.4e-004 -8.85 0.0 48 494 30 117 0.09717 5.9e-007 246 3 M0442_1.02 (ZBTB3)_(Mus_musculus)_(DBD_1.00) NNTGCAGYG 7.0e0000 9.3e-003 -4.67 0.0 130 492 201 594 0.26423 3.8e-005 245 3 M0629_1.02 DMRT3 MATGTATCAAN 1.6e-004 2.1e-007 -15.38 0.0 88 490 147 505 0.17959 8.6e-010 244 3 M0630_1.02 DMRT1 WWTGTWDCNW 7.0e-003 9.3e-006 -11.59 0.0 87 491 143 523 0.17719 3.8e-008 245 3 M0632_1.02 DMRTA2 WHWGTWDYNN 5.6e-004 7.4e-007 -14.11 0.0 111 491 74 173 0.22607 3.0e-009 245 3 M1592_1.02 (SOX3)_(Mus_musculus)_(DBD_1.00) NNNWCAAT 2.6e-005 3.4e-008 -17.19 0.0 107 493 141 393 0.21704 1.4e-010 246 3 M1601_1.02 (SOX11)_(Mus_musculus)_(DBD_1.00) WTTGTBNNN 7.7e0000 1.0e-002 -4.59 0.0 86 492 139 576 0.17480 4.2e-005 245 3 M1950_1.02 ZNF354C GTGGAK 2.8e0000 3.7e-003 -5.60 0.0 19 495 44 573 0.03838 1.5e-005 247 3 M1970_1.02 NFIC TGCCAA 4.7e-005 6.3e-008 -16.58 0.0 51 495 112 591 0.10303 2.6e-010 247 3 M2281_1.02 FOXH1 BNSAATCCACA 1.5e-009 2.0e-012 -26.92 0.0 64 490 131 506 0.13061 8.3e-015 244 3 M2286_1.02 HNF4G TGRMCTTTGNHCYYN 5.0e0000 6.7e-003 -5.01 0.0 64 486 111 574 0.13169 2.8e-005 242 3 M4344_1.02 (ARID2)_(Saccharomyces_cerevisiae)_(DBD_0.26) SGTTGCYA 9.4e0000 1.3e-002 -4.38 0.0 63 493 102 543 0.12779 5.1e-005 246 3 M4698_1.02 HNF4A BTGRMCTTTGVHCYB 8.3e-001 1.1e-003 -6.80 0.0 44 486 85 567 0.09053 4.6e-006 242 3 M5567_1.02 HSF4 GAANVTTCTAGAA 1.2e-001 1.6e-004 -8.74 0.0 26 488 54 494 0.05328 6.6e-007 243 3 M5581_1.02 IRX2 CWTGTCRTGTWN 6.4e-004 8.5e-007 -13.97 0.0 67 489 125 541 0.13701 3.5e-009 244 3 M5582_1.02 IRX5 SWTGTYRTGTWN 2.8e-006 3.7e-009 -19.43 0.0 67 489 134 551 0.13701 1.5e-011 244 3 M5594_1.02 LBX2 CTBRANSTRATTA 1.2e-002 1.6e-005 -11.02 0.0 176 488 270 576 0.36066 6.7e-008 243 3 M5660_1.02 NFIA TTGGCANNDTGCCAR 4.8e-016 6.3e-019 -41.90 0.0 56 486 98 308 0.11523 2.6e-021 242 3 M5662_1.02 NFIB TTGGCAHNDTGCCAR 1.3e-015 1.8e-018 -40.86 0.0 56 486 99 317 0.11523 7.4e-021 242 3 M5664_1.02 NFIX TTGGCANNNHGCCAR 3.1e-012 4.1e-015 -33.14 0.0 44 486 99 439 0.09053 1.7e-017 242 3 M5835_1.02 SOX7 AACAATRWBCAKTGTT 3.2e-013 4.2e-016 -35.40 0.0 117 485 116 227 0.24124 1.8e-018 242 3 M5838_1.02 SOX8 AACAATRTGCAGTGTT 3.9e-019 5.2e-022 -49.00 0.0 83 485 78 142 0.17113 2.2e-024 242 3 M5972_1.02 ZNF410 GANTATTATGGGATGKM 6.0e-001 8.0e-004 -7.13 0.0 104 484 54 140 0.21488 3.3e-006 241 3 M6037_1.02 (IRX1)_(Mus_musculus)_(DBD_1.00) TTTKTCATGTWR 4.1e-001 5.5e-004 -7.50 0.0 125 489 172 492 0.25562 2.3e-006 244 3 M6149_1.02 ARID5B DBYKDGTATTSKR 3.0e-005 4.0e-008 -17.04 0.0 104 488 184 560 0.21311 1.6e-010 243 3 M6166_1.02 CDC5L RWTAYRTTAAMWCVC 2.5e-025 3.3e-028 -63.27 0.0 68 486 172 498 0.13992 1.4e-030 242 3 M6185_1.02 CXXC1 CGKTGKY 8.9e0000 1.2e-002 -4.43 0.0 224 494 297 554 0.45344 4.9e-005 246 3 M6186_1.02 DBP KVTTRCATAAB 1.0e0000 1.4e-003 -6.59 0.0 60 490 103 542 0.12245 5.7e-006 244 3 M6223_1.02 ETV5 GHCAGGAAGWWAY 3.4e-001 4.5e-004 -7.70 0.0 222 488 323 585 0.45492 1.9e-006 243 3 M6268_1.02 HAND1 AAWKCCAGAYVC 4.8e-002 6.4e-005 -9.66 0.0 37 489 80 585 0.07566 2.6e-007 244 3 M6277_1.02 HLF SKRTTACRYAAYH 1.8e-001 2.5e-004 -8.31 0.0 80 488 108 422 0.16393 1.0e-006 243 3 M6287_1.02 HSF2 VGAABRTTCTAGAA 1.0e-001 1.4e-004 -8.90 0.0 57 487 107 565 0.11704 5.6e-007 243 3 M6349_1.02 MYBL2 WYAACHKSYA 2.9e0000 3.9e-003 -5.55 0.0 201 491 291 587 0.40937 1.6e-005 245 3 M6402_1.02 OVOL1 KGTAACKGT 4.2e-002 5.6e-005 -9.79 0.0 76 492 129 540 0.15447 2.3e-007 245 3 M6415_1.02 PDX1 CTAATTACY 5.7e0000 7.5e-003 -4.89 0.0 406 492 404 452 0.82520 3.1e-005 245 3 M6465_1.02 SMAD3 STGTCTGBCY 6.5e0000 8.6e-003 -4.75 0.0 39 491 76 591 0.07943 3.5e-005 245 3 M6471_1.02 SOX13 YATTGTTY 9.5e-004 1.3e-006 -13.58 0.0 81 493 144 552 0.16430 5.1e-009 246 3 M6473_1.02 SOX17 CAAMAATNHHCATTGTCS 1.8e-003 2.5e-006 -12.92 0.0 63 483 85 351 0.13043 1.0e-008 241 3 M6477_1.02 SOX5 WAACAATR 4.1e-002 5.4e-005 -9.82 0.0 81 493 138 552 0.16430 2.2e-007 246 3 M6490_1.02 SRY DAAACAAWR 1.1e-005 1.5e-008 -18.03 0.0 152 492 243 553 0.30894 6.0e-011 245 3 M6496_1.02 STAT4 TTTCCMAGAAAAV 2.4e0000 3.2e-003 -5.73 0.0 68 488 114 556 0.13934 1.3e-005 243 3 M6497_1.02 STAT6 TTCYYHGGAAWYY 1.4e0000 1.8e-003 -6.30 0.0 106 488 165 558 0.21721 7.6e-006 243 3 M6525_1.02 TLX1 YGBYAAKDWGS 3.7e-001 4.9e-004 -7.62 0.0 134 490 207 570 0.27347 2.0e-006 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).