# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 GGAGGGRGAGGGRGAG MEME-1 GGAGGGRGAGGGRGAG 2.3e-070 3.1e-073 -166.97 0.0 109 485 344 599 0.22474 1.3e-075 242 1 CTCCCTCCYYCNCYCC MEME-2 CTCCCTCCYYCNCYCC 6.6e-063 8.8e-066 -149.80 0.0 141 485 381 600 0.29072 3.6e-068 242 1 RRGRGRRGGAGGRRRR MEME-3 RRGRGRRGGAGGRRRR 2.6e-046 3.5e-049 -111.58 0.0 159 485 372 587 0.32784 1.4e-051 242 1 TGTGTGTGTGTGTGTG MEME-4 TGTGTGTGTGTGTGTG 2.1e-001 2.8e-004 -8.17 0.0 177 485 85 152 0.36495 1.2e-006 242 1 YYYCCTCCC MEME-5 YYYCCTCCC 3.4e-043 4.6e-046 -104.39 0.0 122 492 315 597 0.24797 1.9e-048 245 1 CTCTSTCTCTS MEME-6 CTCTSTCTCTS 4.4e-009 5.9e-012 -25.85 0.0 122 490 136 302 0.24898 2.4e-014 244 1 CMYMCACACAMACACA MEME-8 CMYMCACACAMACACA 1.1e0000 1.5e-003 -6.50 0.0 117 485 70 179 0.24124 6.2e-006 242 1 TGACTCA MEME-9 TGACTCA 3.0e0000 4.1e-003 -5.50 0.0 164 494 95 200 0.33198 1.7e-005 246 2 GGAGGGRR DREME-1 GGAGGGRG 5.9e-052 7.9e-055 -124.57 0.0 125 493 299 509 0.25355 3.2e-057 246 2 CCSCCAC DREME-2 CCCCCAC 7.2e-005 9.6e-008 -16.15 0.0 44 494 66 326 0.08907 3.9e-010 246 2 CCDCCTCC DREME-5 CCTCCTCC 2.0e-011 2.7e-014 -31.24 0.0 107 493 153 378 0.21704 1.1e-016 246 3 M0398_1.02 (ZSCAN10)_(Mus_musculus)_(DBD_0.82) NGGRAGTGCNN 3.8e-001 5.1e-004 -7.57 0.0 150 490 229 575 0.30612 2.1e-006 244 3 M0404_1.02 (ZNF202)_(Mus_musculus)_(DBD_0.87) NNNBGGGGSV 9.4e-014 1.3e-016 -36.61 0.0 141 491 275 600 0.28717 5.2e-019 245 3 M0405_1.02 (KLF7)_(Mus_musculus)_(DBD_1.00) DGGGCGKGGY 3.8e-002 5.0e-005 -9.90 0.0 315 491 443 599 0.64155 2.1e-007 245 3 M1906_1.02 SP1 GGGGGMGGGGC 1.9e-013 2.5e-016 -35.92 0.0 152 490 288 597 0.31020 1.0e-018 244 3 M1915_1.02 (ZNF76)_(Xenopus_laevis)_(DBD_0.84) KCRWKGMATBMTGGGARDTV 6.3e-001 8.4e-004 -7.09 0.0 123 481 173 498 0.25572 3.5e-006 240 3 M2273_1.02 E2F6 RGGCGGGARRV 2.0e-033 2.6e-036 -81.93 0.0 168 490 362 600 0.34286 1.1e-038 244 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 2.6e0000 3.5e-003 -5.65 0.0 134 488 208 588 0.27459 1.4e-005 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 9.8e-001 1.3e-003 -6.63 0.0 128 490 203 592 0.26122 5.4e-006 244 3 M2303_1.02 NR2C2 TGACCTYTGACCYCB 6.5e-004 8.7e-007 -13.96 0.0 98 486 171 559 0.20165 3.6e-009 242 3 M2307_1.02 PRDM1 DRAAAGTGAAAGTGR 1.0e0000 1.3e-003 -6.61 0.0 144 486 219 571 0.29630 5.6e-006 242 3 M2314_1.02 SP2 SSSVRGRGGCGGGRC 9.5e-012 1.3e-014 -32.00 0.0 146 486 277 598 0.30041 5.2e-017 242 3 M2390_1.02 EHF SAGGAAGK 3.2e-002 4.2e-005 -10.07 0.0 89 493 156 586 0.18053 1.7e-007 246 3 M2391_1.02 KLF5 DGGGHGGGGC 3.1e-005 4.2e-008 -16.99 0.0 253 491 385 599 0.51527 1.7e-010 245 3 M4453_1.02 BCL11A ADGRGGAASTGARAV 2.7e-002 3.7e-005 -10.21 0.0 62 486 119 583 0.12757 1.5e-007 242 3 M4459_1.02 EGR1 SBGCGKGGGCGGVGGSGSGS 2.8e-011 3.8e-014 -30.90 0.0 119 481 237 591 0.24740 1.6e-016 240 3 M4536_1.02 E2F1 VRRVRGVGCGCGCRS 7.6e-007 1.0e-009 -20.70 0.0 138 486 240 575 0.28395 4.2e-012 242 3 M4537_1.02 E2F4 SGCGGGAARWTBVRR 1.9e-007 2.6e-010 -22.08 0.0 234 486 369 589 0.48148 1.1e-012 242 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 5.5e-038 7.4e-041 -92.40 0.0 114 480 298 599 0.23750 3.1e-043 239 3 M5209_1.02 (SP5)_(Drosophila_melanogaster)_(DBD_0.93) GKGGGCGKRKC 4.6e-001 6.2e-004 -7.39 0.0 296 490 414 595 0.60408 2.5e-006 244 3 M5593_1.02 KLF16 GGGGGCGTGKC 4.9e0000 6.5e-003 -5.04 0.0 212 490 306 592 0.43265 2.7e-005 244 3 M5856_1.02 SP8 RGKGGGCGTGGY 1.5e-002 2.0e-005 -10.82 0.0 261 489 380 593 0.53374 8.2e-008 244 3 M5875_1.02 TBX1 AGGTGTGAAAAAAGGTGTGA 5.9e0000 7.9e-003 -4.84 0.0 129 481 89 227 0.26819 3.3e-005 240 3 M5883_1.02 TBX20 TCACACSTTCACACCT 4.6e0000 6.2e-003 -5.08 0.0 137 485 126 324 0.28247 2.6e-005 242 3 M5977_1.02 ZNF740 GTGGGGGGGK 2.0e-020 2.6e-023 -52.00 0.0 99 491 231 593 0.20163 1.1e-025 245 3 M6119_1.02 SPI1 RAAAAGAGGAAGTGV 5.9e-011 7.8e-014 -30.18 0.0 70 486 157 570 0.14403 3.2e-016 242 3 M6123_1.02 (ZNF281)_(Mus_musculus)_(DBD_1.00) GRGKKGGGGGAGGGG 2.4e-023 3.2e-026 -58.70 0.0 102 486 245 597 0.20988 1.3e-028 242 3 M6154_1.02 ATF5 TAAGGRAGARGK 2.2e-004 3.0e-007 -15.02 0.0 77 489 151 595 0.15746 1.2e-009 244 3 M6199_1.02 EGR2 DGVGTGGGCGG 5.3e-009 7.0e-012 -25.68 0.0 204 490 342 600 0.41633 2.9e-014 244 3 M6201_1.02 EGR4 GGSGGYRGGGM 3.9e0000 5.2e-003 -5.27 0.0 60 490 105 577 0.12245 2.1e-005 244 3 M6204_1.02 ELF2 TDNCAGGAAGTRRVT 8.8e-004 1.2e-006 -13.66 0.0 138 486 233 589 0.28395 4.8e-009 242 3 M6212_1.02 EPAS1 CMCACGYAYDCAC 3.2e-005 4.3e-008 -16.96 0.0 138 488 234 576 0.28279 1.8e-010 243 3 M6221_1.02 ETS2 VMVGGAAGTKS 5.6e-007 7.5e-010 -21.01 0.0 110 490 209 600 0.22449 3.1e-012 244 3 M6267_1.02 GLIS3 GYGGGGGGTM 1.9e-002 2.6e-005 -10.57 0.0 35 491 78 586 0.07128 1.0e-007 245 3 M6321_1.02 KLF15 RSMKGGGAGDKGGGGSS 1.9e-014 2.5e-017 -38.22 0.0 132 484 265 593 0.27273 1.0e-019 241 3 M6322_1.02 KLF1 CAGGGTGKGGC 5.7e0000 7.6e-003 -4.88 0.0 198 490 287 590 0.40408 3.1e-005 244 3 M6324_1.02 KLF4 DGGGYGKGGC 2.3e0000 3.1e-003 -5.77 0.0 295 491 410 599 0.60081 1.3e-005 245 3 M6325_1.02 KLF6 GGGGGCKG 1.2e-001 1.6e-004 -8.73 0.0 135 493 217 594 0.27383 6.6e-007 246 3 M6336_1.02 MAZ RGGGRGGGGAGGGRGGG 8.0e-044 1.1e-046 -105.85 0.0 160 484 374 599 0.33058 4.4e-049 241 3 M6356_1.02 MZF1 RGDGGGGAD 3.0e-023 4.1e-026 -58.46 0.0 58 492 171 598 0.11789 1.7e-028 245 3 M6381_1.02 NR0B1 YSTCCCMCKC 7.2e-021 9.6e-024 -53.00 0.0 159 491 319 599 0.32383 3.9e-026 245 3 M6420_1.02 PLAG1 GGRGGSMHNDVKAGGGG 1.9e-026 2.6e-029 -65.82 0.0 104 484 256 596 0.21488 1.1e-031 241 3 M6442_1.02 PURA CCMBGCCCNCCMMBWCC 7.2e-021 9.6e-024 -53.00 0.0 68 484 185 600 0.14050 4.0e-026 241 3 M6456_1.02 RREB1 DKGKKKGKGGKTGKTTKGGGKT 1.5e-002 2.0e-005 -10.81 0.0 93 479 147 501 0.19415 8.4e-008 239 3 M6482_1.02 SP3 VGVVGGGGGCGGGGCBRGSS 5.9e-009 7.9e-012 -25.56 0.0 161 481 290 598 0.33472 3.3e-014 240 3 M6483_1.02 SP4 GSGGSCRGGGGSGGGGSGGSSSSG 4.9e-001 6.5e-004 -7.33 0.0 129 477 200 555 0.27044 2.7e-006 238 3 M6515_1.02 TFDP1 AWWKRGCGGGAAAY 3.1e-007 4.2e-010 -21.59 0.0 91 487 167 533 0.18686 1.7e-012 243 3 M6535_1.02 WT1 GMGGGGGCGKGGG 2.1e-019 2.8e-022 -49.64 0.0 106 488 241 599 0.21721 1.1e-024 243 3 M6539_1.02 ZBTB7B CGGVGRRGGGGMGSRGGSGGGH 3.6e-024 4.8e-027 -60.61 0.0 133 479 290 582 0.27766 2.0e-029 239 3 M6548_1.02 ZIC1 KGGGWGGTS 2.4e-005 3.2e-008 -17.25 0.0 70 492 144 598 0.14228 1.3e-010 245 3 M6549_1.02 ZIC2 KGGGTGGTC 6.8e-001 9.2e-004 -7.00 0.0 30 492 66 599 0.06098 3.7e-006 245 3 M6552_1.02 ZNF148 KGVGKGGGGGAGGGG 6.9e-027 9.2e-030 -66.85 0.0 102 486 254 598 0.20988 3.8e-032 242 3 M6553_1.02 ZNF219 GDGGGGGGYGGA 2.1e-013 2.8e-016 -35.80 0.0 65 489 160 595 0.13292 1.2e-018 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).