# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 GYGAGGGAGCTGGGGTATTTAT MEME-1 GYGAGGGAGCTGGGGTATTTAT 3.8e-196 5.0e-199 -456.61 0.0 51 479 243 269 0.10647 2.1e-201 239 1 YYTGGCACYNTGCCAA MEME-2 YYTGGCACYNTGCCAA 2.7e-108 3.6e-111 -254.31 0.0 35 485 138 189 0.07216 1.5e-113 242 1 ACACCAACTCCYRTCAGTCATT MEME-3 ACACCAACTCCYRTCAGTCATT 3.4e-057 4.6e-060 -136.63 0.0 97 479 190 290 0.20251 1.9e-062 239 1 GCCCCGGCTCCCCCGC MEME-4 GCCCCGGCTCCCCCGC 7.9e-128 1.0e-130 -299.29 0.0 47 485 221 345 0.09691 4.3e-133 242 1 CCTCAGAGTTATCCCACCYRAG MEME-5 CCTCAGAGTTATCCCACCYRAG 5.7e-040 7.6e-043 -96.98 0.0 79 479 184 389 0.16493 3.2e-045 239 1 YRTGYTCTAYACTGTCTCCCAGAGKTCCCCA MEME-6 YRTGYTCTAYACTGTCTCCCAGAGKTCCCCA 5.2e-045 6.9e-048 -108.59 0.0 154 470 139 154 0.32766 3.0e-050 234 1 SSGBGSSGSSAGSSSGSGSGSG MEME-7 SSGBGSSGSSAGSSSGSGSGSG 1.2e-002 1.6e-005 -11.06 0.0 47 479 49 220 0.09812 6.6e-008 239 1 GGTTGAGGGCTGCTCY MEME-8 GGTTGAGGGCTGCTCY 1.2e-028 1.6e-031 -70.94 0.0 135 485 162 250 0.27835 6.4e-034 242 1 ACACCAACTCCC MEME-10 ACACCAACTCCC 5.5e-074 7.3e-077 -175.31 0.0 83 489 266 487 0.16973 3.0e-079 244 2 ATACHCCA DREME-1 ATACCCCA 5.3e-125 7.0e-128 -292.79 0.0 89 493 194 203 0.18053 2.8e-130 246 2 CTCCCTY DREME-2 CTCCCTC 5.8e-093 7.8e-096 -219.00 0.0 62 494 197 309 0.12551 3.2e-098 246 2 GKATAA DREME-3 GKATAA 1.9e-043 2.5e-046 -104.98 0.0 73 495 140 259 0.14747 1.0e-048 247 2 DTGCCAA DREME-4 DTGCCAA 7.5e-037 9.9e-040 -89.81 0.0 46 494 88 181 0.09312 4.0e-042 246 2 AKCCGGG DREME-5 AGCCGGG 1.1e-017 1.5e-020 -45.64 0.0 58 494 53 104 0.11741 6.1e-023 246 2 CTGAGR DREME-6 CTGAGG 2.4e-003 3.2e-006 -12.66 0.0 71 495 104 419 0.14343 1.3e-008 247 2 CTGGSA DREME-7 CTGGSA 1.1e-002 1.5e-005 -11.10 0.0 197 495 233 445 0.39798 6.1e-008 247 2 CARTGA DREME-8 CARTGA 5.7e0000 7.6e-003 -4.88 0.0 137 495 123 324 0.27677 3.1e-005 247 2 CCARCTC DREME-10 CCARCTC 3.9e-111 5.2e-114 -260.85 0.0 54 494 196 288 0.10931 2.1e-116 246 3 M0395_1.02 (ZNF187)_(Mus_musculus)_(DBD_0.88) GTACTAAT 6.3e-022 8.3e-025 -55.45 0.0 69 493 177 553 0.13996 3.4e-027 246 3 M0404_1.02 (ZNF202)_(Mus_musculus)_(DBD_0.87) NNNKGGGGSV 6.7e0000 8.9e-003 -4.72 0.0 59 491 104 585 0.12016 3.7e-005 245 3 M0405_1.02 (KLF7)_(Mus_musculus)_(DBD_1.00) DGGGCGKGGY 3.7e-001 4.9e-004 -7.62 0.0 75 491 129 570 0.15275 2.0e-006 245 3 M0437_1.02 (ZNF32)_(Mus_musculus)_(DBD_0.99) TATRTATRT 3.0e-021 4.0e-024 -53.88 0.0 70 492 148 426 0.14228 1.6e-026 245 3 M0443_1.02 (KLF12)_(Mus_musculus)_(DBD_1.00) DGGGYGKGKY 4.3e-001 5.8e-004 -7.46 0.0 75 491 129 569 0.15275 2.4e-006 245 3 M0629_1.02 DMRT3 MATGTATCAAN 4.1e0000 5.4e-003 -5.21 0.0 68 490 103 496 0.13878 2.2e-005 244 3 M0633_1.02 DMRT2 KAATKTATWN 8.7e-015 1.2e-017 -39.00 0.0 65 491 144 500 0.13238 4.7e-020 245 3 M0635_1.02 (DMRTC2)_(Mus_musculus)_(DBD_1.00) NAMATGTATHMWN 3.3e-001 4.3e-004 -7.74 0.0 74 488 119 515 0.15164 1.8e-006 243 3 M0718_1.02 FOXK1 NNRTMAACAH 7.8e-007 1.0e-009 -20.69 0.0 69 491 137 544 0.14053 4.2e-012 245 3 M0737_1.02 (FOXB2)_(Mus_musculus)_(DBD_0.94) WRWGTAAAYA 4.0e-027 5.3e-030 -67.42 0.0 69 491 186 542 0.14053 2.2e-032 245 3 M0747_1.02 (FOXL2)_(Mus_musculus)_(DBD_0.70) WNNRTAAAYA 5.3e-034 7.0e-037 -83.25 0.0 69 491 199 544 0.14053 2.9e-039 245 3 M0937_1.02 (SIX6)_(Mus_musculus)_(DBD_1.00) HKATMYN 1.3e-008 1.7e-011 -24.79 0.0 72 494 111 375 0.14575 7.0e-014 246 3 M0952_1.02 (SIX2)_(Mus_musculus)_(DBD_1.00) BGATMCNN 8.9e-010 1.2e-012 -27.47 0.0 73 493 137 476 0.14807 4.8e-015 246 3 M0994_1.02 (SIX4)_(Mus_musculus)_(DBD_1.00) NYKAYMCBN 2.0e-004 2.7e-007 -15.14 0.0 84 492 141 507 0.17073 1.1e-009 245 3 M1049_1.02 (SIX1)_(Mus_musculus)_(DBD_1.00) NYGATAYNNN 8.3e-020 1.1e-022 -50.55 0.0 71 491 172 534 0.14460 4.5e-025 245 3 M1884_1.02 MEF2A DKCTAAAAATAGMHH 5.6e-005 7.4e-008 -16.41 0.0 66 486 113 464 0.13580 3.1e-010 242 3 M1906_1.02 SP1 GGGGGMGGGGC 2.9e-005 3.9e-008 -17.06 0.0 42 490 95 559 0.08571 1.6e-010 244 3 M1915_1.02 (ZNF76)_(Xenopus_laevis)_(DBD_0.84) KCRWKGMATBMTGGGARDTV 1.3e-005 1.8e-008 -17.84 0.0 75 481 140 524 0.15593 7.4e-011 240 3 M1968_1.02 EBF1 TCCCWGGGGRV 1.1e-003 1.4e-006 -13.48 0.0 186 490 277 553 0.37959 5.7e-009 244 3 M1970_1.02 NFIC TGCCAA 1.5e-021 2.0e-024 -54.59 0.0 35 495 123 597 0.07071 8.0e-027 247 3 M2273_1.02 E2F6 RGGCGGGARRV 5.8e-007 7.7e-010 -20.98 0.0 42 490 101 570 0.08571 3.2e-012 244 3 M2301_1.02 NFYB VHMYBRRCCAATCAG 2.4e-003 3.1e-006 -12.67 0.0 110 486 160 469 0.22634 1.3e-008 242 3 M2314_1.02 SP2 SSVVRGRGGCGGGRC 1.4e-004 1.9e-007 -15.50 0.0 34 486 80 548 0.06996 7.7e-010 242 3 M2391_1.02 KLF5 DGGGHGGGGC 1.8e-006 2.4e-009 -19.83 0.0 49 491 108 548 0.09980 1.0e-011 245 3 M4459_1.02 EGR1 SBGCGKGGGCGGVRGSGSGG 1.5e-001 2.0e-004 -8.53 0.0 49 481 77 428 0.10187 8.2e-007 240 3 M4461_1.02 ETS1 GCMTBCTGGGARWTGTAGTYY 4.1e-001 5.4e-004 -7.53 0.0 188 480 118 215 0.39167 2.3e-006 239 3 M4473_1.02 PBX3 NBCDGCCAATSRGVR 5.0e-004 6.7e-007 -14.22 0.0 304 486 422 569 0.62551 2.8e-009 242 3 M4527_1.02 SMARCC2 RRACTACAAYTCCCAGVAKGC 4.5e-004 5.9e-007 -14.34 0.0 122 480 95 216 0.25417 2.5e-009 239 3 M4536_1.02 E2F1 VRRVRGVGCGCGCRS 1.1e-004 1.5e-007 -15.70 0.0 42 486 77 429 0.08642 6.3e-010 242 3 M4537_1.02 E2F4 GGCGGGAARWTBVRR 2.1e-001 2.8e-004 -8.17 0.0 46 486 82 507 0.09465 1.2e-006 242 3 M4567_1.02 FOXA2 NCWRWGTAAACANNN 1.4e-010 1.9e-013 -29.32 0.0 68 486 147 538 0.13992 7.7e-016 242 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 4.6e0000 6.1e-003 -5.10 0.0 46 480 82 543 0.09583 2.6e-005 239 3 M4612_1.02 CTCFL CCRSCAGGGGGCGCY 1.3e-004 1.8e-007 -15.53 0.0 198 486 237 428 0.40741 7.4e-010 242 3 M4640_1.02 ZBTB7A GGGSRRGGGKCBSNG 4.3e-029 5.8e-032 -71.93 0.0 44 486 147 538 0.09053 2.4e-034 242 3 M4692_1.02 SIX5 ACTACAAYTC 2.5e-022 3.3e-025 -56.38 0.0 51 491 129 445 0.10387 1.3e-027 245 3 M5339_1.02 DLX1 NNTAATTRNN 5.3e-006 7.0e-009 -18.77 0.0 69 491 129 516 0.14053 2.9e-011 245 3 M5343_1.02 DLX5 NTAATTRN 1.5e-001 2.0e-004 -8.50 0.0 79 493 127 525 0.16024 8.2e-007 246 3 M5345_1.02 DMBX1 NHTAATCCBH 7.7e-001 1.0e-003 -6.88 0.0 177 491 253 557 0.36049 4.2e-006 245 3 M5446_1.02 FOXD4L2 GTAAACA 8.8e-024 1.2e-026 -59.71 0.0 66 494 176 552 0.13360 4.8e-029 246 3 M5460_1.02 FOXL1 RTAAACA 4.0e-033 5.3e-036 -81.22 0.0 66 494 189 532 0.13360 2.2e-038 246 3 M5500_1.02 GSC VYTAATCCSH 2.3e0000 3.1e-003 -5.79 0.0 199 491 267 537 0.40530 1.2e-005 245 3 M5512_1.02 HIC2 VSYGGGCAY 3.1e-006 4.1e-009 -19.32 0.0 50 492 115 594 0.10163 1.7e-011 245 3 M5587_1.02 JDP2 ATGASTCAT 3.3e-002 4.3e-005 -10.04 0.0 102 492 127 400 0.20732 1.8e-007 245 3 M5616_1.02 MEF2B RCTAWAAATAGC 1.5e-013 1.9e-016 -36.17 0.0 67 489 108 329 0.13701 8.0e-019 244 3 M5660_1.02 NFIA TTGGCANNDTGCCAR 3.4e-068 4.5e-071 -161.98 0.0 30 486 138 347 0.06173 1.9e-073 242 3 M5662_1.02 NFIB TTGGCAHNDTGCCAR 5.2e-066 6.9e-069 -156.95 0.0 30 486 139 364 0.06173 2.8e-071 242 3 M5664_1.02 NFIX TTGGCANNNNGCCAR 4.3e-051 5.7e-054 -122.60 0.0 30 486 144 496 0.06173 2.4e-056 242 3 M5717_1.02 PITX1 NHTAATCCC 8.5e0000 1.1e-002 -4.48 0.0 172 492 241 560 0.34959 4.6e-005 245 3 M5977_1.02 ZNF740 GTGGGGGGGK 9.9e-001 1.3e-003 -6.63 0.0 39 491 71 517 0.07943 5.4e-006 245 3 M6114_1.02 FOXA1 WAWGYAAAYA 4.0e-017 5.4e-020 -44.37 0.0 69 491 163 537 0.14053 2.2e-022 245 3 M6123_1.02 (ZNF281)_(Mus_musculus)_(DBD_1.00) GRGKTGGGGGAGGGG 1.0e-011 1.3e-014 -31.95 0.0 44 486 111 524 0.09053 5.5e-017 242 3 M6184_1.02 CUX1 RBRSNDATCGATSB 2.4e-009 3.2e-012 -26.46 0.0 95 487 171 502 0.19507 1.3e-014 243 3 M6188_1.02 DLX2 ATAATTRB 1.1e-008 1.4e-011 -24.98 0.0 65 493 124 479 0.13185 5.7e-014 246 3 M6194_1.02 E2F5 SGCGCSAAAH 3.3e-001 4.4e-004 -7.73 0.0 39 491 54 347 0.07943 1.8e-006 245 3 M6199_1.02 EGR2 DGVGTGGGCGG 1.0e-003 1.4e-006 -13.50 0.0 74 490 128 517 0.15102 5.6e-009 244 3 M6201_1.02 EGR4 GGSGGYRGGGM 5.2e-001 6.9e-004 -7.28 0.0 58 490 94 493 0.11837 2.8e-006 244 3 M6221_1.02 ETS2 VMVGGAAGTKS 9.2e0000 1.2e-002 -4.41 0.0 350 490 470 598 0.71429 5.0e-005 244 3 M6234_1.02 FOXA3 RVWAARYAAAYAD 4.1e-002 5.4e-005 -9.83 0.0 68 488 118 535 0.13934 2.2e-007 243 3 M6238_1.02 FOXF1 WAAATAAACAW 2.0e-002 2.7e-005 -10.52 0.0 70 490 116 505 0.14286 1.1e-007 244 3 M6241_1.02 FOXJ2 WAAAYAAACA 7.4e-002 9.8e-005 -9.23 0.0 69 491 114 514 0.14053 4.0e-007 245 3 M6279_1.02 HMGA1 AAAATWN 3.5e-006 4.6e-009 -19.19 0.0 64 494 128 546 0.12955 1.9e-011 246 3 M6295_1.02 HOXB1 CCATCMATCW 1.5e0000 2.0e-003 -6.20 0.0 113 491 136 421 0.23014 8.3e-006 245 3 M6321_1.02 KLF15 RSMKGGGAGDKGGGGSS 4.7e-004 6.2e-007 -14.29 0.0 48 484 99 539 0.09917 2.6e-009 241 3 M6322_1.02 KLF1 CAGGGTGKGGC 6.9e0000 9.2e-003 -4.69 0.0 50 490 85 538 0.10204 3.8e-005 244 3 M6323_1.02 KLF3 HRCYWGGGTGKGGCT 4.5e-009 5.9e-012 -25.85 0.0 48 486 112 537 0.09877 2.5e-014 242 3 M6324_1.02 KLF4 DGGGYGKGGC 1.8e0000 2.4e-003 -6.01 0.0 49 491 88 554 0.09980 1.0e-005 245 3 M6336_1.02 MAZ RGGGDRGGGAGGGRGGG 4.7e-015 6.3e-018 -39.61 0.0 32 484 101 549 0.06612 2.6e-020 241 3 M6339_1.02 MECP2 YYCCGGS 3.3e-003 4.4e-006 -12.34 0.0 182 494 252 517 0.36842 1.8e-008 246 3 M6342_1.02 MEF2D BCTAWAAATAGC 2.9e-009 3.8e-012 -26.30 0.0 67 489 125 456 0.13701 1.6e-014 244 3 M6370_1.02 NFKB2 GRAATBYCCCT 3.8e-018 5.0e-021 -46.75 0.0 60 490 159 574 0.12245 2.0e-023 244 3 M6373_1.02 NFYC YAGCCAATSAGVGS 2.8e0000 3.8e-003 -5.58 0.0 137 487 202 554 0.28131 1.6e-005 243 3 M6381_1.02 NR0B1 YSTCCCMCKC 1.5e0000 2.0e-003 -6.22 0.0 19 491 46 581 0.03870 8.1e-006 245 3 M6384_1.02 NR1H4 AGGTCANTGACCYY 2.3e-008 3.0e-011 -24.23 0.0 69 487 132 491 0.14168 1.2e-013 243 3 M6419_1.02 PKNOX1 MATCARTCAABYB 7.6e-001 1.0e-003 -6.90 0.0 106 488 158 524 0.21721 4.2e-006 243 3 M6482_1.02 SP3 VGVVGGGGGCGGGGCBRGSS 1.5e-014 2.0e-017 -38.48 0.0 37 481 106 522 0.07692 8.1e-020 240 3 M6483_1.02 SP4 GSGGCCRGGGGSGGGGSGGSSSSR 6.7e-004 8.9e-007 -13.93 0.0 39 477 62 344 0.08176 3.7e-009 238 3 M6507_1.02 TEAD1 YACATTCCWSMKSH 5.6e-005 7.4e-008 -16.42 0.0 67 487 134 568 0.13758 3.0e-010 243 3 M6509_1.02 TEAD4 AAAAAYAKCYCT 4.1e-002 5.4e-005 -9.82 0.0 59 489 102 510 0.12065 2.2e-007 244 3 M6525_1.02 TLX1 YGBYAAKDWGS 4.1e-015 5.4e-018 -39.76 0.0 34 490 107 581 0.06939 2.2e-020 244 3 M6535_1.02 WT1 GMGGGGGCGKGGG 8.0e-031 1.1e-033 -75.93 0.0 56 488 166 514 0.11475 4.4e-036 243 3 M6539_1.02 ZBTB7B CGGVGRRGGGGMGSRGGSGGGH 6.7e-019 8.9e-022 -48.47 0.0 37 479 101 424 0.07724 3.7e-024 239 3 M6542_1.02 ZBTB6 VGRTGATRGAGCC 1.7e-029 2.2e-032 -72.90 0.0 44 488 144 516 0.09016 9.0e-035 243 3 M6552_1.02 ZNF148 KGVGKGGGGGAGGGG 7.6e-020 1.0e-022 -50.64 0.0 52 486 142 527 0.10700 4.2e-025 242 3 M6553_1.02 ZNF219 GDGGGGGGYGGA 3.5e-001 4.7e-004 -7.67 0.0 41 489 75 512 0.08384 1.9e-006 244 3 M6555_1.02 ZNF333 SKATAATGA 1.2e-001 1.6e-004 -8.74 0.0 76 492 114 475 0.15447 6.5e-007 245 3 M6556_1.02 ZNF350 SGGCMMCAAABNHYTGCBBCCCST 5.1e-010 6.8e-013 -28.02 0.0 57 477 118 466 0.11950 2.9e-015 238 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).