# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 AAATAAATAAATAAATAAATAAATAAATAAA MEME-1 AAATAAATAAATAAATAAATAAATAAATAAA 5.8e-280 7.8e-283 -649.58 0.0 34 470 316 386 0.07234 3.3e-285 234 1 AGAGYGAGACTCYGTCTCAAAA MEME-2 AGAGYGAGACTCYGTCTCAAAA 8.9e-089 1.2e-091 -209.36 0.0 109 479 268 364 0.22756 5.0e-094 239 1 TAAATAAATAAA MEME-3 TAAATAAATAAA 5.9e-228 8.0e-231 -529.82 0.0 43 489 321 441 0.08793 3.3e-233 244 2 TAAATAAA DREME-1 TAAATAAA 6.4e-240 8.6e-243 -557.37 0.0 49 493 324 400 0.09939 3.5e-245 246 2 GTCTCR DREME-2 GTCTCA 1.0e-020 1.4e-023 -52.64 0.0 99 495 166 377 0.20000 5.6e-026 247 2 ACAGWG DREME-3 ACAGAG 4.4e-031 5.9e-034 -76.52 0.0 119 495 222 424 0.24040 2.4e-036 247 2 CTCAAVA DREME-4 CTCAAAA 1.0e-069 1.3e-072 -165.49 0.0 98 494 222 336 0.19838 5.5e-075 246 2 CCTGGGY DREME-5 CCTGGGY 6.2e-009 8.3e-012 -25.52 0.0 228 494 215 320 0.46154 3.4e-014 246 2 ARACTCC DREME-6 ARACTCC 8.1e-010 1.1e-012 -27.55 0.0 90 494 85 201 0.18219 4.4e-015 246 3 M0104_1.02 (ARID3B)_(Mus_musculus)_(DBD_0.99) AWATTAATWAN 2.9e-034 3.9e-037 -83.84 0.0 74 490 208 544 0.15102 1.6e-039 244 3 M0105_1.02 (ARID3C)_(Mus_musculus)_(DBD_0.87) NTTTDATHN 6.3e-002 8.5e-005 -9.37 0.0 80 492 129 518 0.16260 3.5e-007 245 3 M0398_1.02 (ZSCAN10)_(Mus_musculus)_(DBD_0.82) NGKRAGTGCNN 1.1e-011 1.5e-014 -31.84 0.0 164 490 285 565 0.33469 6.1e-017 244 3 M0424_1.02 (SNAI3)_(Mus_musculus)_(DBD_0.75) NNTGACAKNN 6.1e-003 8.2e-006 -11.71 0.0 113 491 194 590 0.23014 3.3e-008 245 3 M0436_1.02 (ZNF35)_(Mus_musculus)_(DBD_0.96) TTRTTKDHYN 2.0e-064 2.7e-067 -153.27 0.0 65 491 250 581 0.13238 1.1e-069 245 3 M0442_1.02 (ZBTB3)_(Mus_musculus)_(DBD_1.00) NNTGCAGYG 1.8e-014 2.4e-017 -38.28 0.0 230 492 386 592 0.46748 9.7e-020 245 3 M0633_1.02 DMRT2 KAATKTATWN 8.8e-095 1.2e-097 -223.18 0.0 51 491 255 558 0.10387 4.8e-100 245 3 M0718_1.02 FOXK1 DNRTMAACAH 3.8e-005 5.2e-008 -16.78 0.0 121 491 213 588 0.24644 2.1e-010 245 3 M0719_1.02 FOXG1 RTAAACAW 4.0e-020 5.4e-023 -51.27 0.0 51 493 146 565 0.10345 2.2e-025 246 3 M0728_1.02 (FOXJ1)_(Mus_musculus)_(DBD_1.00) NRTAAACAAANN 6.8e-044 9.2e-047 -106.00 0.0 49 489 189 586 0.10020 3.8e-049 244 3 M0736_1.02 (FOXK2)_(Mus_musculus)_(DBD_0.90) RTAAACAA 8.6e-012 1.2e-014 -32.09 0.0 59 493 144 586 0.11968 4.7e-017 246 3 M0737_1.02 (FOXB2)_(Mus_musculus)_(DBD_0.94) WRWGTAAAYA 5.2e-118 7.0e-121 -276.67 0.0 45 491 272 578 0.09165 2.8e-123 245 3 M0747_1.02 (FOXL2)_(Mus_musculus)_(DBD_0.70) WNNRTAAAYA 1.9e-098 2.5e-101 -231.64 0.0 63 491 292 586 0.12831 1.0e-103 245 3 M0896_1.02 VENTX TTAATTAG 9.1e-013 1.2e-015 -34.34 0.0 51 493 128 555 0.10345 5.0e-018 246 3 M0897_1.02 HOXB13 DTTWAYDRBN 2.3e-001 3.1e-004 -8.07 0.0 381 491 460 536 0.77597 1.3e-006 245 3 M0906_1.02 (VTN)_(Mus_musculus)_(DBD_0.79) NMTTAATTAR 4.7e-007 6.3e-010 -21.19 0.0 51 491 100 464 0.10387 2.6e-012 245 3 M1030_1.02 (NKX2-3)_(Mus_musculus)_(DBD_1.00) NVYACTTVD 4.4e0000 5.9e-003 -5.14 0.0 290 492 399 595 0.58943 2.4e-005 245 3 M1528_1.02 (RFX6)_(Mus_musculus)_(DBD_0.66) NCNTRGYWAC 5.0e-003 6.7e-006 -11.91 0.0 123 491 208 593 0.25051 2.7e-008 245 3 M1582_1.02 (HMG20B)_(Mus_musculus)_(DBD_0.94) NWAWATAATWN 3.4e-044 4.6e-047 -106.69 0.0 50 490 180 530 0.10204 1.9e-049 244 3 M1583_1.02 (BBX)_(Mus_musculus)_(DBD_0.99) TTCATTGA 3.7e-002 4.9e-005 -9.91 0.0 95 493 81 243 0.19270 2.0e-007 246 3 M1605_1.02 (SOX1)_(Mus_musculus)_(DBD_1.00) ATTSWHNNNN 4.0e-003 5.3e-006 -12.14 0.0 281 491 386 563 0.57230 2.2e-008 245 3 M1668_1.02 PRKRIR NYCVNVSKRNNN 8.0e-008 1.1e-010 -22.95 0.0 143 489 251 579 0.29243 4.4e-013 244 3 M1884_1.02 MEF2A DKCTAAAAATAGMHH 1.6e-002 2.1e-005 -10.76 0.0 72 486 127 543 0.14815 8.7e-008 242 3 M2283_1.02 FOXP1 HWWADGTAAACAAAR 3.9e-063 5.2e-066 -150.32 0.0 56 486 229 571 0.11523 2.1e-068 242 3 M2287_1.02 (HOXC9)_(Mus_musculus)_(DBD_0.98) RGCMATAAATCAB 5.5e-036 7.4e-039 -87.80 0.0 58 488 179 517 0.11885 3.1e-041 243 3 M2385_1.02 FOXP2 RWGTAAACAVR 1.1e-039 1.4e-042 -96.34 0.0 46 490 172 566 0.09388 5.9e-045 244 3 M4452_1.02 BATF TYYYRWWATGASTCA 2.4e-004 3.2e-007 -14.94 0.0 74 486 134 529 0.15226 1.3e-009 242 3 M4467_1.02 MEF2C DDKCYAAAAATAGMH 5.7e-013 7.7e-016 -34.81 0.0 74 486 167 564 0.15226 3.2e-018 242 3 M4476_1.02 RFX5 TCABYWGTTGCYRGG 1.0e0000 1.4e-003 -6.58 0.0 316 486 420 570 0.65021 5.8e-006 242 3 M4551_1.02 ZNF274 YTCAYACTGGAGAGAAA 8.0e-015 1.1e-017 -39.07 0.0 158 484 183 317 0.32645 4.5e-020 241 3 M4567_1.02 FOXA2 NMWRWGTAAACANNN 2.4e-044 3.3e-047 -107.04 0.0 56 486 204 586 0.11523 1.3e-049 242 3 M4572_1.02 MAFF TGCTGACTCAGCAWW 9.3e-004 1.2e-006 -13.59 0.0 290 486 342 472 0.59671 5.2e-009 242 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 1.1e0000 1.5e-003 -6.49 0.0 286 480 376 548 0.59583 6.4e-006 239 3 M4629_1.02 NFE2 VRTGACTCAGCANWWYB 1.5e0000 2.0e-003 -6.22 0.0 280 484 314 463 0.57851 8.3e-006 241 3 M4681_1.02 BACH2 TGCTGAGTCA 8.2e-001 1.1e-003 -6.81 0.0 305 491 346 482 0.62118 4.5e-006 245 3 M4698_1.02 HNF4A BTGRMCTTTGVHCYB 3.2e-004 4.3e-007 -14.67 0.0 150 486 241 564 0.30864 1.8e-009 242 3 M5287_1.02 ALX4 HTAATYNAATTAN 2.5e-119 3.4e-122 -279.70 0.0 50 488 273 530 0.10246 1.4e-124 243 3 M5291_1.02 ARX YTAATTNRATTAN 1.5e-168 2.1e-171 -393.01 0.0 50 488 317 522 0.10246 8.6e-174 243 3 M5294_1.02 BARHL2 NHTAAAYGNY 7.2e-008 9.7e-011 -23.06 0.0 45 491 102 521 0.09165 4.0e-013 245 3 M5300_1.02 BARX1 TAATBGNTWTTTAATBG 3.9e-001 5.3e-004 -7.54 0.0 176 484 188 392 0.36364 2.2e-006 241 3 M5322_1.02 CPEB1 TTTTTATT 2.9e-017 3.9e-020 -44.69 0.0 65 493 163 567 0.13185 1.6e-022 246 3 M5335_1.02 CUX2 ATCGATAHNDTTATYGAT 9.9e-218 1.3e-220 -506.28 0.0 45 483 314 429 0.09317 5.6e-223 241 3 M5348_1.02 DRGX NTAATYHAATTAN 2.0e-085 2.7e-088 -201.64 0.0 50 488 234 526 0.10246 1.1e-090 243 3 M5425_1.02 ETV6 CCGGAASCGGAAGTR 2.5e-002 3.4e-005 -10.28 0.0 298 486 281 380 0.61317 1.4e-007 242 3 M5435_1.02 FOXB1 TCGCYGTGTCATTC 2.9e-004 3.9e-007 -14.75 0.0 133 487 179 443 0.27310 1.6e-009 243 3 M5445_1.02 FOXD2 DRTMAATATTWDYD 6.6e-006 8.9e-009 -18.54 0.0 59 487 119 532 0.12115 3.6e-011 243 3 M5446_1.02 FOXD4L2 RTAAACA 3.8e-071 5.1e-074 -168.76 0.0 46 494 220 584 0.09312 2.1e-076 246 3 M5460_1.02 FOXL1 RTAAACA 1.6e-099 2.2e-102 -234.09 0.0 54 494 271 579 0.10931 8.8e-105 246 3 M5544_1.02 HOXC10 DTTTWATKDB 1.8e-018 2.5e-021 -47.45 0.0 67 491 171 574 0.13646 1.0e-023 245 3 M5547_1.02 HOXC11 DRTCRTWAAAH 2.4e0000 3.3e-003 -5.72 0.0 132 490 168 468 0.26939 1.3e-005 244 3 M5555_1.02 HOXD11 RTCGTAAAAH 1.1e0000 1.5e-003 -6.49 0.0 139 491 168 440 0.28310 6.2e-006 245 3 M5584_1.02 ISX YTAATCTAATTAR 2.2e-120 2.9e-123 -282.14 0.0 50 488 263 491 0.10246 1.2e-125 243 3 M5604_1.02 LMX1A YTAATTAA 4.7e-001 6.3e-004 -7.38 0.0 71 493 102 455 0.14402 2.5e-006 246 3 M5605_1.02 LMX1B TTAATTRN 1.7e0000 2.2e-003 -6.10 0.0 77 493 125 550 0.15619 9.1e-006 246 3 M5621_1.02 MEIS3 SCTGTCAH 1.4e-004 1.9e-007 -15.46 0.0 113 493 199 587 0.22921 7.8e-010 246 3 M5631_1.02 MIXL1 NBTAATTRVN 1.0e0000 1.4e-003 -6.59 0.0 381 491 470 552 0.77597 5.6e-006 245 3 M5635_1.02 MNX1 TTTAATTRNH 2.6e-013 3.5e-016 -35.58 0.0 51 491 131 565 0.10387 1.4e-018 245 3 M5637_1.02 MSX1 TAATTGSWWTTTAATTRS 2.4e-011 3.2e-014 -31.08 0.0 53 483 108 430 0.10973 1.3e-016 241 3 M5697_1.02 ONECUT3 DTTATYGATTTTTY 2.0e-159 2.7e-162 -372.04 0.0 63 487 334 514 0.12936 1.1e-164 243 3 M5711_1.02 PAX9 KKCASTCAWGCGTGACS 2.7e-002 3.7e-005 -10.21 0.0 206 484 135 225 0.42562 1.5e-007 241 3 M5714_1.02 PHOX2A TAATYYAATTA 8.6e-068 1.2e-070 -161.04 0.0 50 490 214 533 0.10204 4.7e-073 244 3 M5715_1.02 PHOX2B TAATYYAATTA 9.3e-058 1.3e-060 -137.93 0.0 50 490 201 535 0.10204 5.1e-063 244 3 M5740_1.02 POU4F1 ATGMATAATTAATG 2.5e-164 3.4e-167 -383.30 0.0 45 487 305 531 0.09240 1.4e-169 243 3 M5743_1.02 POU4F3 RTGMATWATTAATGAV 3.0e-154 4.0e-157 -360.12 0.0 47 485 300 528 0.09691 1.7e-159 242 3 M5753_1.02 PROX1 YAAGACGYCTTA 5.1e-004 6.9e-007 -14.19 0.0 89 489 93 285 0.18200 2.8e-009 244 3 M5941_1.02 UNCX NTAATYBAATTAN 1.0e-035 1.4e-038 -87.17 0.0 58 488 188 560 0.11885 5.7e-041 243 3 M6114_1.02 FOXA1 WAWGYAAAYA 4.9e-103 6.5e-106 -242.20 0.0 63 491 295 579 0.12831 2.7e-108 245 3 M6141_1.02 ALX1 TAATBYAATTAY 6.6e-014 8.9e-017 -36.96 0.0 51 489 130 545 0.10429 3.7e-019 244 3 M6147_1.02 ARID3A TWWAWTTTGATWYYVWTTAATH 5.4e-157 7.3e-160 -366.43 0.0 47 479 298 508 0.09812 3.0e-162 239 3 M6157_1.02 BARX2 TYRWTAATKR 3.1e0000 4.2e-003 -5.48 0.0 377 491 441 523 0.76782 1.7e-005 245 3 M6187_1.02 DDIT3 GGGGATTGCABBB 6.2e-008 8.4e-011 -23.20 0.0 206 488 322 560 0.42213 3.5e-013 243 3 M6221_1.02 ETS2 VMVGGAAGTKS 1.9e0000 2.5e-003 -5.98 0.0 338 490 457 594 0.68980 1.0e-005 244 3 M6234_1.02 FOXA3 RVWAARYAAAYAD 6.9e-112 9.2e-115 -262.57 0.0 54 488 288 583 0.11066 3.8e-117 243 3 M6235_1.02 FOXC1 CYWAAGTAAACAWHG 1.1e-047 1.5e-050 -114.75 0.0 56 486 198 535 0.11523 6.1e-053 242 3 M6236_1.02 FOXC2 YCTRDSWAAACAAAC 1.9e0000 2.6e-003 -5.95 0.0 412 486 478 524 0.84774 1.1e-005 242 3 M6237_1.02 FOXD3 AAACAAACA 5.7e-102 7.7e-105 -239.73 0.0 52 492 268 571 0.10569 3.1e-107 245 3 M6238_1.02 FOXF1 WAAATAAACAW 1.0e-146 1.4e-149 -342.76 0.0 62 490 339 572 0.12653 5.7e-152 244 3 M6239_1.02 FOXF2 HWADGTAAACA 9.4e-095 1.3e-097 -223.12 0.0 64 490 283 564 0.13061 5.2e-100 244 3 M6241_1.02 FOXJ2 WAAAYAAAYA 1.4e-163 1.9e-166 -381.58 0.0 39 491 298 570 0.07943 7.8e-169 245 3 M6242_1.02 FOXJ3 TAAACAWWAAMMA 3.2e-075 4.3e-078 -178.15 0.0 58 488 243 548 0.11885 1.7e-080 243 3 M6244_1.02 FOXM1 RWAAWCAMWCAAV 1.7e-078 2.2e-081 -185.70 0.0 62 488 266 589 0.12705 9.2e-084 243 3 M6245_1.02 FOXO1 AAAWWVWAAACAAVHH 2.8e-088 3.8e-091 -208.21 0.0 61 485 274 577 0.12577 1.6e-093 242 3 M6246_1.02 FOXO3 MKGWAAACAARYM 2.7e-077 3.6e-080 -182.93 0.0 50 488 238 582 0.10246 1.5e-082 243 3 M6247_1.02 FOXO4 MRTAAACAA 3.6e-042 4.9e-045 -102.03 0.0 50 492 185 574 0.10163 2.0e-047 245 3 M6250_1.02 FOXQ1 AAATAAACAATD 1.3e-087 1.8e-090 -206.66 0.0 59 489 258 538 0.12065 7.3e-093 244 3 M6262_1.02 GFI1B WGCMGTGATTT 2.0e0000 2.7e-003 -5.90 0.0 320 490 414 561 0.65306 1.1e-005 244 3 M6269_1.02 HBP1 AYYCATTGA 4.3e-001 5.8e-004 -7.45 0.0 56 492 104 581 0.11382 2.4e-006 245 3 M6276_1.02 HINFP DMSHHMGCGGACGTTV 3.4e-007 4.6e-010 -21.50 0.0 233 485 240 362 0.48041 1.9e-012 242 3 M6285_1.02 ONECUT1 WWTATTGATTTWDH 2.5e-159 3.4e-162 -371.79 0.0 63 487 344 544 0.12936 1.4e-164 243 3 M6289_1.02 HOXA9 WCATAAAYYRTH 4.0e-029 5.4e-032 -72.00 0.0 61 489 182 566 0.12474 2.2e-034 244 3 M6293_1.02 HOXA7 KCCAATCKATYGAKB 1.4e-002 1.8e-005 -10.91 0.0 270 486 381 574 0.55556 7.5e-008 242 3 M6297_1.02 HOXB7 MATYAATCAA 2.6e-127 3.6e-130 -298.06 0.0 47 491 274 532 0.09572 1.5e-132 245 3 M6298_1.02 HOXB8 BMATTAATCAA 9.7e-096 1.3e-098 -225.38 0.0 50 490 244 518 0.10204 5.4e-101 244 3 M6299_1.02 HOXC6 AAAGTAATAAATCAT 7.8e-176 1.0e-178 -409.81 0.0 58 486 325 477 0.11934 4.3e-181 242 3 M6301_1.02 HOXD10 AATTAAARCA 8.1e-009 1.1e-011 -25.25 0.0 105 491 197 561 0.21385 4.4e-014 245 3 M6304_1.02 HOXD9 HMATNAAWYT 2.6e-003 3.5e-006 -12.55 0.0 107 491 176 546 0.21792 1.4e-008 245 3 M6329_1.02 LHX3 AAAATTAATTARY 1.2e-090 1.6e-093 -213.70 0.0 60 488 255 508 0.12295 6.4e-096 243 3 M6348_1.02 MTF1 MGKGCCGTGTGCAAADS 4.0e-009 5.4e-012 -25.95 0.0 170 484 233 441 0.35124 2.2e-014 241 3 M6374_1.02 NKX2-1 STCAAGKGCH 2.2e0000 3.0e-003 -5.81 0.0 235 491 336 594 0.47862 1.2e-005 245 3 M6377_1.02 NKX2-8 TTCAAGKRC 2.9e0000 3.9e-003 -5.55 0.0 238 492 331 579 0.48374 1.6e-005 245 3 M6378_1.02 NKX3-1 WWTAAGTATWTWW 5.5e-168 7.4e-171 -391.74 0.0 44 488 311 552 0.09016 3.1e-173 243 3 M6399_1.02 ONECUT2 DKSWTKWTATKGATTTTWYYT 1.4e-187 1.9e-190 -436.82 0.0 52 480 338 516 0.10833 8.2e-193 239 3 M6400_1.02 OTX1 BTAATCCT 2.3e0000 3.1e-003 -5.77 0.0 313 493 415 578 0.63489 1.3e-005 246 3 M6413_1.02 PBX2 VMATCAATCAMWTYM 2.0e-050 2.7e-053 -121.03 0.0 56 486 214 585 0.11523 1.1e-055 242 3 M6417_1.02 POU1F1 RWATATTCATKAR 7.2e-012 9.7e-015 -32.26 0.0 52 488 130 567 0.10656 4.0e-017 243 3 M6426_1.02 POU3F2 CATRAATWWT 3.7e-120 5.0e-123 -281.61 0.0 49 491 280 566 0.09980 2.0e-125 245 3 M6438_1.02 PROP1 RASHAATTAAHWTVR 2.8e-017 3.8e-020 -44.72 0.0 66 486 166 564 0.13580 1.6e-022 242 3 M6471_1.02 SOX13 YATTGTTY 8.5e0000 1.1e-002 -4.48 0.0 167 493 237 566 0.33874 4.7e-005 246 3 M6472_1.02 SOX15 CWTTGTT 8.0e0000 1.1e-002 -4.54 0.0 236 494 323 577 0.47773 4.4e-005 246 3 M6509_1.02 TEAD4 AAAAAYAKCYCT 6.3e-002 8.5e-005 -9.37 0.0 79 489 130 529 0.16155 3.5e-007 244 3 M6510_1.02 TEF TGTTTATRTAAMTK 2.3e-036 3.1e-039 -88.69 0.0 65 487 205 575 0.13347 1.3e-041 243 3 M6534_1.02 VSX2 WDAGCTAATTA 7.7e-001 1.0e-003 -6.87 0.0 376 490 396 465 0.76735 4.3e-006 244 3 M6542_1.02 ZBTB6 VGRTGATRGAGCC 1.1e-003 1.4e-006 -13.46 0.0 128 488 200 532 0.26230 5.8e-009 243 3 M6546_1.02 ZFHX3 ATTAWTAATTA 2.8e-163 3.7e-166 -380.91 0.0 44 490 297 518 0.08980 1.5e-168 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).