# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 TTATTTATTTATTTATTTATTTATTTATTT MEME-1 TTATTTATTTATTTATTTATTTATTTATTT 3.8e-182 5.1e-185 -424.35 0.0 37 471 184 194 0.07856 2.2e-187 235 1 TTATTTATTTATTTAT MEME-2 TTATTTATTTATTTAT 1.5e-117 1.9e-120 -275.64 0.0 45 485 190 287 0.09278 8.1e-123 242 1 TTTTGAGAYRGAGTCTCRCTCT MEME-3 TTTTGAGAYRGAGTCTCRCTCT 4.6e-052 6.1e-055 -124.83 0.0 105 479 151 202 0.21921 2.6e-057 239 1 CYCGCCGCCYGVKTTC MEME-4 CYCGCCGCCYGVKTTC 1.8e-032 2.3e-035 -79.74 0.0 227 485 332 430 0.46804 9.7e-038 242 1 GAGACRGAGTCTYGCT MEME-5 GAGACRGAGTCTYGCT 1.2e-026 1.5e-029 -66.35 0.0 107 485 131 224 0.22062 6.3e-032 242 1 WTTTATTTW MEME-6 WTTTATTTW 7.4e-086 9.9e-089 -202.64 0.0 74 492 205 312 0.15041 4.0e-091 245 1 WTWTKWKKWTBTTTKTHTTTWT MEME-7 WTWTKWKKWTBTTTKTHTTTWT 6.2e-069 8.2e-072 -163.68 0.0 39 479 172 424 0.08142 3.4e-074 239 1 CTGTCTCAWAAW MEME-10 CTGTCTCAWAAW 3.6e-016 4.9e-019 -42.17 0.0 93 489 88 171 0.19018 2.0e-021 244 2 TAAATAAA DREME-1 TAAATAAA 1.1e-146 1.5e-149 -342.67 0.0 49 493 182 208 0.09939 6.2e-152 246 2 RTCTCAAA DREME-2 GTCTCAAA 6.9e-029 9.2e-032 -71.46 0.0 93 493 97 150 0.18864 3.7e-034 246 2 CTCYGYC DREME-3 CTCYGYC 1.3e-004 1.8e-007 -15.54 0.0 218 494 209 346 0.44130 7.3e-010 246 2 AGACTCY DREME-4 AGACTCC 4.2e-015 5.6e-018 -39.73 0.0 106 494 82 144 0.21457 2.3e-020 246 2 CGCCGCC DREME-5 CGCCGCC 1.5e0000 2.1e-003 -6.19 0.0 236 494 106 163 0.47773 8.3e-006 246 3 M0104_1.02 (ARID3B)_(Mus_musculus)_(DBD_0.99) AWATTAATWAN 4.1e-024 5.5e-027 -60.47 0.0 78 490 174 464 0.15918 2.2e-029 244 3 M0105_1.02 (ARID3C)_(Mus_musculus)_(DBD_0.87) NTTTDATHN 5.8e-014 7.7e-017 -37.10 0.0 52 492 128 526 0.10569 3.1e-019 245 3 M0398_1.02 (ZSCAN10)_(Mus_musculus)_(DBD_0.82) NGKRAGTGCNN 2.1e-002 2.9e-005 -10.46 0.0 164 490 249 565 0.33469 1.2e-007 244 3 M0436_1.02 (ZNF35)_(Mus_musculus)_(DBD_0.96) TTRTTKDHYN 1.4e-038 1.8e-041 -93.80 0.0 53 491 181 552 0.10794 7.5e-044 245 3 M0437_1.02 (ZNF32)_(Mus_musculus)_(DBD_0.99) TATRTATRT 1.8e-051 2.4e-054 -123.45 0.0 52 492 160 380 0.10569 9.9e-057 245 3 M0442_1.02 (ZBTB3)_(Mus_musculus)_(DBD_1.00) NNTGCAGYG 7.6e-001 1.0e-003 -6.89 0.0 208 492 308 598 0.42276 4.2e-006 245 3 M0608_1.02 MLL NNNRSCGNDN 4.9e-002 6.5e-005 -9.64 0.0 257 491 287 447 0.52342 2.6e-007 245 3 M0633_1.02 DMRT2 KAATKTATWN 5.0e-042 6.7e-045 -101.72 0.0 57 491 174 464 0.11609 2.7e-047 245 3 M0718_1.02 FOXK1 NNRTMAACAH 9.5e-038 1.3e-040 -91.86 0.0 61 491 193 545 0.12424 5.2e-043 245 3 M0719_1.02 FOXG1 RTAAACAW 5.9e-027 7.8e-030 -67.02 0.0 61 493 152 450 0.12373 3.2e-032 246 3 M0728_1.02 (FOXJ1)_(Mus_musculus)_(DBD_1.00) NRTAAACAAANN 8.5e-037 1.1e-039 -89.67 0.0 39 489 149 537 0.07975 4.7e-042 244 3 M0736_1.02 (FOXK2)_(Mus_musculus)_(DBD_0.90) RTAAACAA 8.2e-010 1.1e-012 -27.55 0.0 63 493 135 533 0.12779 4.4e-015 246 3 M0737_1.02 (FOXB2)_(Mus_musculus)_(DBD_0.94) WRWGTAAAYA 4.2e-071 5.6e-074 -168.67 0.0 41 491 198 529 0.08350 2.3e-076 245 3 M0747_1.02 (FOXL2)_(Mus_musculus)_(DBD_0.70) WNNRTAAAYA 2.9e-050 3.8e-053 -120.70 0.0 63 491 216 544 0.12831 1.6e-055 245 3 M0896_1.02 VENTX TTAATTAG 2.5e-016 3.4e-019 -42.53 0.0 59 493 130 456 0.11968 1.4e-021 246 3 M0897_1.02 HOXB13 DTTWAYDRBN 2.0e-011 2.6e-014 -31.26 0.0 65 491 138 512 0.13238 1.1e-016 245 3 M0906_1.02 (VTN)_(Mus_musculus)_(DBD_0.79) NMTTAATTAR 2.6e-018 3.5e-021 -47.11 0.0 49 491 116 428 0.09980 1.4e-023 245 3 M1007_1.02 (HOXA11)_(Mus_musculus)_(DBD_1.00) TTWAYKDBN 1.1e0000 1.4e-003 -6.54 0.0 122 492 98 265 0.24797 5.9e-006 245 3 M1018_1.02 (HLX)_(Mus_musculus)_(DBD_1.00) YHATNNN 1.4e0000 1.9e-003 -6.26 0.0 64 494 34 120 0.12955 7.8e-006 246 3 M1157_1.02 (HOXB9)_(PBM_CONSTRUCTS)_(DBD_1.00) WTTWATKRBN 2.0e-014 2.7e-017 -38.15 0.0 65 491 148 525 0.13238 1.1e-019 245 3 M1582_1.02 (HMG20B)_(Mus_musculus)_(DBD_0.94) NWAWATAATWN 1.5e-026 2.0e-029 -66.10 0.0 48 490 133 449 0.09796 8.1e-032 244 3 M1583_1.02 (BBX)_(Mus_musculus)_(DBD_0.99) TTCATTGA 4.9e-033 6.6e-036 -81.01 0.0 49 493 161 535 0.09939 2.7e-038 246 3 M1605_1.02 (SOX1)_(Mus_musculus)_(DBD_1.00) ATTSWHNNNN 3.0e0000 3.9e-003 -5.53 0.0 49 491 86 542 0.09980 1.6e-005 245 3 M1882_1.02 IRF1 AAANNGAAAGTGAAASYRRRN 4.9e0000 6.5e-003 -5.03 0.0 66 480 100 488 0.13750 2.7e-005 239 3 M2270_1.02 DUX4 TAAYYYAATCA 1.1e0000 1.5e-003 -6.53 0.0 48 490 74 447 0.09796 6.0e-006 244 3 M2273_1.02 E2F6 RGGCGGGARRV 4.7e0000 6.3e-003 -5.07 0.0 270 490 360 567 0.55102 2.6e-005 244 3 M2283_1.02 FOXP1 HWWADGTAAACAAAR 1.0e-032 1.3e-035 -80.30 0.0 58 486 172 510 0.11934 5.5e-038 242 3 M2287_1.02 (HOXC9)_(Mus_musculus)_(DBD_0.98) RGCMATAAATCAB 1.1e-038 1.5e-041 -94.02 0.0 64 488 180 460 0.13115 6.1e-044 243 3 M2385_1.02 FOXP2 RWGTAAACAVR 3.8e-048 5.1e-051 -115.81 0.0 60 490 197 498 0.12245 2.1e-053 244 3 M2388_1.02 SREBF2 RTGGGGTGAY 2.8e0000 3.7e-003 -5.61 0.0 259 491 314 506 0.52749 1.5e-005 245 3 M4452_1.02 BATF TYYYRDWATGASTCA 1.2e-002 1.5e-005 -11.08 0.0 116 486 169 487 0.23868 6.4e-008 242 3 M4467_1.02 MEF2C NDKCYAAAAATAGMH 1.1e-004 1.5e-007 -15.72 0.0 72 486 127 502 0.14815 6.2e-010 242 3 M4471_1.02 PAX5 BCAGYSRAGCGTGAC 1.5e0000 2.0e-003 -6.20 0.0 358 486 461 566 0.73663 8.4e-006 242 3 M4537_1.02 E2F4 GGCGGGAARWTBVRR 3.7e-002 5.0e-005 -9.91 0.0 272 486 356 532 0.55967 2.1e-007 242 3 M4567_1.02 FOXA2 NCWRWGTAAACANNN 3.9e-051 5.2e-054 -122.70 0.0 62 486 209 513 0.12757 2.1e-056 242 3 M4681_1.02 BACH2 TGCTGAGTCA 5.0e0000 6.7e-003 -5.01 0.0 289 491 284 414 0.58859 2.7e-005 245 3 M4708_1.02 TBP TATGCAAATA 1.1e-001 1.4e-004 -8.87 0.0 47 491 80 475 0.09572 5.7e-007 245 3 M4840_1.02 (FEZF1)_(Drosophila_melanogaster)_(DBD_0.91) AAAWGMGCAWC 4.8e0000 6.4e-003 -5.05 0.0 56 490 93 531 0.11429 2.6e-005 244 3 M5287_1.02 ALX4 HTAATYNAATTAN 2.3e-070 3.1e-073 -166.97 0.0 48 488 193 444 0.09836 1.3e-075 243 3 M5291_1.02 ARX YTAATTNRATTAN 5.8e-080 7.8e-083 -189.07 0.0 48 488 201 432 0.09836 3.2e-085 243 3 M5294_1.02 BARHL2 NHTAAAYGNY 2.2e-022 3.0e-025 -56.47 0.0 57 491 153 524 0.11609 1.2e-027 245 3 M5300_1.02 BARX1 TAATBGNTWTTTAATBG 5.8e-014 7.8e-017 -37.10 0.0 60 484 120 414 0.12397 3.2e-019 241 3 M5322_1.02 CPEB1 YTTTTATY 9.6e-011 1.3e-013 -29.68 0.0 59 493 130 524 0.11968 5.2e-016 246 3 M5335_1.02 CUX2 ATCGATAHNDTTATYGAT 5.1e-134 6.8e-137 -313.54 0.0 37 483 178 247 0.07660 2.8e-139 241 3 M5348_1.02 DRGX NTAATYHAATTAN 1.6e-063 2.1e-066 -151.24 0.0 48 488 181 430 0.09836 8.6e-069 243 3 M5349_1.02 DUXA NTRAYYTAATCAN 9.7e-008 1.3e-010 -22.77 0.0 40 488 87 465 0.08197 5.3e-013 243 3 M5445_1.02 FOXD2 DRTMAATATTWDYD 1.3e-011 1.7e-014 -31.69 0.0 45 487 100 442 0.09240 7.1e-017 243 3 M5446_1.02 FOXD4L2 GTAAACA 1.5e-040 2.1e-043 -98.29 0.0 54 494 185 547 0.10931 8.4e-046 246 3 M5460_1.02 FOXL1 RTAAACA 3.5e-048 4.7e-051 -115.88 0.0 60 494 200 514 0.12146 1.9e-053 246 3 M5503_1.02 GSX2 DYTAATKRSN 2.1e-010 2.9e-013 -28.88 0.0 67 491 137 503 0.13646 1.2e-015 245 3 M5518_1.02 HMX1 NNTTAATTGNT 2.3e-001 3.0e-004 -8.11 0.0 108 490 158 507 0.22041 1.2e-006 244 3 M5519_1.02 HMX2 NDTTAAKTGBT 1.4e0000 1.8e-003 -6.30 0.0 56 490 94 521 0.11429 7.5e-006 244 3 M5544_1.02 HOXC10 DTTTWATKDB 1.1e-019 1.4e-022 -50.30 0.0 73 491 172 525 0.14868 5.8e-025 245 3 M5551_1.02 HOXC12 TTTTATTRC 4.8e-006 6.4e-009 -18.86 0.0 60 492 116 509 0.12195 2.6e-011 245 3 M5553_1.02 HOXC13 CYAATAAAAH 4.6e-001 6.2e-004 -7.39 0.0 71 491 111 499 0.14460 2.5e-006 245 3 M5555_1.02 HOXD11 RTCGTAAAAH 1.9e0000 2.5e-003 -5.98 0.0 119 491 155 469 0.24236 1.0e-005 245 3 M5584_1.02 ISX YTAATCTAATTAR 2.6e-066 3.4e-069 -157.65 0.0 44 488 165 374 0.09016 1.4e-071 243 3 M5604_1.02 LMX1A YTAATTAA 9.1e-017 1.2e-019 -43.56 0.0 55 493 126 458 0.11156 4.9e-022 246 3 M5605_1.02 LMX1B TTAATTRN 1.0e-016 1.4e-019 -43.42 0.0 59 493 140 503 0.11968 5.6e-022 246 3 M5635_1.02 MNX1 TTTAATTRNH 1.1e-016 1.5e-019 -43.35 0.0 59 491 138 488 0.12016 6.1e-022 245 3 M5637_1.02 MSX1 TAATTGSWWTTTAATTGS 1.7e-033 2.3e-036 -82.05 0.0 57 483 148 397 0.11801 9.6e-039 241 3 M5697_1.02 ONECUT3 DTTATYGATTTTTY 7.0e-058 9.3e-061 -138.23 0.0 59 487 190 423 0.12115 3.8e-063 243 3 M5702_1.02 PAX1 DKCABTCAWGCGTGACG 4.5e0000 6.1e-003 -5.11 0.0 344 484 172 206 0.71074 2.5e-005 241 3 M5704_1.02 PAX3 TAATYRATTA 1.3e-020 1.7e-023 -52.42 0.0 37 491 92 356 0.07536 7.0e-026 245 3 M5709_1.02 PAX7 WAATYRATTA 1.7e-007 2.2e-010 -22.22 0.0 37 491 74 398 0.07536 9.1e-013 245 3 M5714_1.02 PHOX2A TAATYYAATTA 5.4e-044 7.2e-047 -106.25 0.0 48 490 158 440 0.09796 3.0e-049 244 3 M5715_1.02 PHOX2B TAATBYAATTA 2.7e-041 3.7e-044 -100.02 0.0 48 490 156 449 0.09796 1.5e-046 244 3 M5735_1.02 POU3F3 WAATTWGCATAWW 1.4e0000 1.9e-003 -6.26 0.0 54 488 80 439 0.11066 7.9e-006 243 3 M5740_1.02 POU4F1 ATGMATAATTAATG 2.2e-079 3.0e-082 -187.72 0.0 41 487 189 438 0.08419 1.2e-084 243 3 M5743_1.02 POU4F3 RTGMATWATTAATGAV 1.7e-080 2.2e-083 -190.31 0.0 43 485 191 425 0.08866 9.3e-086 242 3 M5753_1.02 PROX1 YAAGACGYCTTA 3.8e0000 5.1e-003 -5.28 0.0 89 489 76 263 0.18200 2.1e-005 244 3 M5941_1.02 UNCX NTAATYBAATTAN 2.6e-042 3.4e-045 -102.38 0.0 42 488 152 474 0.08607 1.4e-047 243 3 M5972_1.02 ZNF410 GANTATTATGGGATGKM 1.3e-001 1.7e-004 -8.66 0.0 106 484 54 132 0.21901 7.2e-007 241 3 M6114_1.02 FOXA1 WAWGYAAAYA 5.3e-046 7.1e-049 -110.86 0.0 67 491 213 531 0.13646 2.9e-051 245 3 M6141_1.02 ALX1 TAATBYAATTAB 7.6e-029 1.0e-031 -71.37 0.0 55 489 152 469 0.11247 4.2e-034 244 3 M6147_1.02 ARID3A TWWAWTTTGATWYYVWTTAATH 3.7e-075 5.0e-078 -177.99 0.0 51 479 196 407 0.10647 2.1e-080 239 3 M6157_1.02 BARX2 TYRWTAATKR 3.4e-006 4.5e-009 -19.22 0.0 51 491 101 489 0.10387 1.8e-011 245 3 M6187_1.02 DDIT3 GGGGATTGCABBB 5.1e-002 6.8e-005 -9.60 0.0 308 488 403 550 0.63115 2.8e-007 243 3 M6234_1.02 FOXA3 RVWAARYAAAYAD 1.2e-046 1.6e-049 -112.37 0.0 58 488 197 523 0.11885 6.5e-052 243 3 M6235_1.02 FOXC1 CYWAAGTAAACAWHG 1.7e-036 2.2e-039 -89.00 0.0 58 486 163 440 0.11934 9.2e-042 242 3 M6237_1.02 FOXD3 AAACAAACA 5.9e-045 7.9e-048 -108.45 0.0 50 492 179 520 0.10163 3.2e-050 245 3 M6238_1.02 FOXF1 WAAATAAACAW 8.0e-053 1.1e-055 -126.58 0.0 60 490 202 494 0.12245 4.4e-058 244 3 M6239_1.02 FOXF2 HWADGTAAACA 1.9e-051 2.5e-054 -123.42 0.0 62 490 202 488 0.12653 1.0e-056 244 3 M6241_1.02 FOXJ2 WAAAYAAACA 3.3e-065 4.4e-068 -155.10 0.0 39 491 183 509 0.07943 1.8e-070 245 3 M6242_1.02 FOXJ3 TAAACAWWAAMMA 4.7e-037 6.3e-040 -90.26 0.0 46 488 151 470 0.09426 2.6e-042 243 3 M6244_1.02 FOXM1 RWAAWCAMWCAAV 1.2e-037 1.7e-040 -91.60 0.0 58 488 189 550 0.11885 6.8e-043 243 3 M6245_1.02 FOXO1 AAAWWVWAAACAAVHH 8.2e-052 1.1e-054 -124.25 0.0 51 485 191 513 0.10515 4.5e-057 242 3 M6246_1.02 FOXO3 MKGWAAACAARYM 1.4e-060 1.9e-063 -144.43 0.0 52 488 209 536 0.10656 7.7e-066 243 3 M6247_1.02 FOXO4 MRTAAACAA 8.2e-018 1.1e-020 -45.96 0.0 52 492 136 527 0.10569 4.5e-023 245 3 M6250_1.02 FOXQ1 AAATAAACAATD 2.6e-049 3.5e-052 -118.48 0.0 55 489 178 447 0.11247 1.4e-054 244 3 M6257_1.02 GATA5 WVANWGATAABTYRRHK 3.5e-009 4.7e-012 -26.09 0.0 46 484 103 491 0.09504 1.9e-014 241 3 M6269_1.02 HBP1 AYYCATTGA 3.8e-014 5.1e-017 -37.52 0.0 46 492 114 496 0.09350 2.1e-019 245 3 M6281_1.02 HNF1A KGKTAAWBATTAACY 3.9e-019 5.2e-022 -49.01 0.0 38 486 104 439 0.07819 2.2e-024 242 3 M6282_1.02 HNF1B GTTAAWYATTAACY 5.0e-013 6.7e-016 -34.94 0.0 57 487 121 453 0.11704 2.7e-018 243 3 M6285_1.02 ONECUT1 WWTATTGATTTWDH 1.1e-069 1.5e-072 -165.39 0.0 47 487 190 443 0.09651 6.1e-075 243 3 M6289_1.02 HOXA9 WCATAAAYYRTH 8.1e-036 1.1e-038 -87.42 0.0 47 489 151 474 0.09611 4.4e-041 244 3 M6290_1.02 HOXA13 CCAATAAWAHC 1.4e-008 1.9e-011 -24.67 0.0 52 490 112 509 0.10612 7.9e-014 244 3 M6292_1.02 HOXA5 CATTAATYAR 6.6e-009 8.8e-012 -25.45 0.0 43 491 96 484 0.08758 3.6e-014 245 3 M6296_1.02 HOXB6 KKCATMAATCAWY 1.7e-036 2.3e-039 -88.98 0.0 64 488 163 407 0.13115 9.4e-042 243 3 M6297_1.02 HOXB7 MATYAATCAA 6.0e-063 7.9e-066 -149.90 0.0 45 491 174 423 0.09165 3.2e-068 245 3 M6298_1.02 HOXB8 BMATTAATCAA 1.2e-056 1.6e-059 -135.38 0.0 46 490 167 418 0.09388 6.6e-062 244 3 M6299_1.02 HOXC6 AAAGTAATAAATCAT 1.7e-089 2.3e-092 -211.02 0.0 42 486 184 367 0.08642 9.4e-095 242 3 M6301_1.02 HOXD10 AATTAAARCA 4.5e-010 6.0e-013 -28.15 0.0 65 491 135 514 0.13238 2.4e-015 245 3 M6304_1.02 HOXD9 HMATNAAWYT 3.9e-007 5.2e-010 -21.37 0.0 77 491 134 471 0.15682 2.1e-012 245 3 M6312_1.02 IRF7 GAAASYGAAA 1.2e-002 1.6e-005 -11.05 0.0 61 491 115 565 0.12424 6.5e-008 245 3 M6329_1.02 LHX3 AAAATTAATTARY 3.7e-050 4.9e-053 -120.45 0.0 62 488 179 403 0.12705 2.0e-055 243 3 M6348_1.02 MTF1 MGKGCCGTGYGCAAARS 3.0e-003 4.0e-006 -12.43 0.0 152 484 179 399 0.31405 1.7e-008 241 3 M6378_1.02 NKX3-1 WWTAAGTATWTWW 2.0e-084 2.6e-087 -199.35 0.0 40 488 192 436 0.08197 1.1e-089 243 3 M6399_1.02 ONECUT2 DKSWTKWTATKGATTTTWYYT 4.2e-079 5.6e-082 -187.10 0.0 54 480 202 397 0.11250 2.3e-084 239 3 M6412_1.02 PBX1 VHMATCAATCAAWYH 1.9e-010 2.6e-013 -29.00 0.0 60 486 125 487 0.12346 1.1e-015 242 3 M6413_1.02 PBX2 VMATCAATCAMWTYM 1.7e-044 2.2e-047 -107.42 0.0 42 486 160 496 0.08642 9.2e-050 242 3 M6417_1.02 POU1F1 RWATATTCATKAR 8.3e-030 1.1e-032 -73.58 0.0 36 488 126 491 0.07377 4.6e-035 243 3 M6426_1.02 POU3F2 CATRAATWWT 1.2e-055 1.6e-058 -133.07 0.0 45 491 183 512 0.09165 6.6e-061 245 3 M6427_1.02 POU4F2 MARCTCATTAATR 1.1e-005 1.5e-008 -18.01 0.0 66 488 109 432 0.13525 6.2e-011 243 3 M6429_1.02 POU6F1 CATAAWTTATGCR 9.1e-002 1.2e-004 -9.02 0.0 60 488 71 321 0.12295 5.0e-007 243 3 M6438_1.02 PROP1 RASHAATTAAHWTVR 3.1e-019 4.1e-022 -49.24 0.0 66 486 152 477 0.13580 1.7e-024 242 3 M6471_1.02 SOX13 YATTGTTY 8.5e-002 1.1e-004 -9.08 0.0 55 493 98 533 0.11156 4.6e-007 246 3 M6510_1.02 TEF TGTTTATRTAAMTK 8.8e-035 1.2e-037 -85.03 0.0 69 487 189 494 0.14168 4.8e-040 243 3 M6546_1.02 ZFHX3 ATTAWTAATTA 8.9e-079 1.2e-081 -186.34 0.0 52 490 201 414 0.10612 4.9e-084 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).