# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 GGAACAGMADGKGCRARG MEME-1 GGAACAGMADGKGCRARG 2.2e-191 2.9e-194 -445.63 0.0 59 483 379 581 0.12215 1.2e-196 241 1 GGAASRGCATTCCAGG MEME-2 GGAASRGCATTCCAGG 1.8e-055 2.4e-058 -132.67 0.0 65 485 165 315 0.13402 9.9e-061 242 1 CHGCCTCWGRGC MEME-3 CHGCCTCWGRGC 9.0e-011 1.2e-013 -29.74 0.0 83 489 114 318 0.16973 5.0e-016 244 2 CYSTTCC DREME-1 CTSTTCC 1.4e-147 1.9e-150 -344.75 0.0 62 494 315 502 0.12551 7.7e-153 246 2 DGGAAC DREME-2 DGGAAC 5.4e-120 7.3e-123 -281.23 0.0 67 495 301 516 0.13535 3.0e-125 247 2 CTTTGCAY DREME-3 CTTTGCAC 3.7e-029 5.0e-032 -72.07 0.0 69 493 69 102 0.13996 2.0e-034 246 2 ATTCCAG DREME-4 ATTCCAG 5.5e-010 7.4e-013 -27.93 0.0 58 494 39 84 0.11741 3.0e-015 246 2 CTCWGAGC DREME-5 CTCTGAGC 1.4e-006 1.8e-009 -20.11 0.0 75 493 41 88 0.15213 7.5e-012 246 3 M0198_1.02 (SOHLH2)_(Mus_musculus)_(DBD_0.84) NRYVCGTGCN 1.8e-003 2.5e-006 -12.91 0.0 37 491 81 557 0.07536 1.0e-008 245 3 M0212_1.02 (TCFL5)_(Mus_musculus)_(DBD_1.00) NBCDCGHGVN 6.5e-001 8.7e-004 -7.05 0.0 43 491 62 389 0.08758 3.6e-006 245 3 M0216_1.02 (NHLH2)_(Mus_musculus)_(DBD_1.00) NGCAGCTGYN 3.7e-002 5.0e-005 -9.91 0.0 81 491 145 585 0.16497 2.0e-007 245 3 M0398_1.02 (ZSCAN10)_(Mus_musculus)_(DBD_0.82) NGKRAGTGCNN 2.6e-001 3.5e-004 -7.97 0.0 62 490 114 583 0.12653 1.4e-006 244 3 M0433_1.02 (ZBTB12)_(Mus_musculus)_(DBD_1.00) NYCTAGAACN 1.2e-012 1.6e-015 -34.07 0.0 77 491 175 589 0.15682 6.5e-018 245 3 M1359_1.02 (MYPOP)_(Mus_musculus)_(DBD_0.97) NWTTGCGCCR 6.3e-001 8.4e-004 -7.08 0.0 57 491 89 473 0.11609 3.4e-006 245 3 M1841_1.02 AR GNACABNVTGTTCYY 9.1e-046 1.2e-048 -110.32 0.0 56 486 202 563 0.11523 5.1e-051 242 3 M1889_1.02 MAX RRGCACATGK 4.9e-001 6.6e-004 -7.33 0.0 77 491 117 495 0.15682 2.7e-006 245 3 M1955_1.02 STAT1 TTTCYRGGAAA 9.3e-002 1.3e-004 -8.98 0.0 48 490 88 521 0.09796 5.1e-007 244 3 M2273_1.02 E2F6 RGGCGGGARRV 1.6e-002 2.2e-005 -10.72 0.0 80 490 147 591 0.16327 9.1e-008 244 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 9.2e-006 1.2e-008 -18.21 0.0 74 488 149 584 0.15164 5.1e-011 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 3.4e0000 4.6e-003 -5.39 0.0 304 490 419 597 0.62041 1.9e-005 244 3 M2299_1.02 (MYF5)_(Mus_musculus)_(DBD_0.90) NRNRRCAGCTGSN 1.5e-001 2.0e-004 -8.50 0.0 52 488 100 576 0.10656 8.3e-007 243 3 M2305_1.02 NRF1 YGCGCABGCGC 7.9e-003 1.1e-005 -11.45 0.0 54 490 83 411 0.11020 4.4e-008 244 3 M2307_1.02 PRDM1 DRAAAGTGAAAGTGR 6.5e-001 8.8e-004 -7.04 0.0 108 486 172 565 0.22222 3.6e-006 242 3 M2390_1.02 EHF SAGGAAGK 3.2e-001 4.3e-004 -7.74 0.0 231 493 326 577 0.46856 1.8e-006 246 3 M4427_1.02 CTCF NYGGCCASCAGRKGGCRSYVB 9.9e-002 1.3e-004 -8.92 0.0 42 480 77 494 0.08750 5.6e-007 239 3 M4428_1.02 NR3C1 RGVACAYTBTGTYC 1.8e-039 2.4e-042 -95.82 0.0 57 487 191 551 0.11704 1.0e-044 243 3 M4453_1.02 BCL11A ADGRGGAASTGARAV 2.6e-006 3.6e-009 -19.46 0.0 60 486 131 585 0.12346 1.5e-011 242 3 M4479_1.02 TCF12 VSAGCAGSTGB 6.0e-001 8.1e-004 -7.11 0.0 46 490 89 580 0.09388 3.3e-006 244 3 M4522_1.02 ELK4 CCGGAAGYGS 2.2e0000 2.9e-003 -5.83 0.0 59 491 105 575 0.12016 1.2e-005 245 3 M4532_1.02 MYC CCACGTGSYY 2.0e0000 2.7e-003 -5.93 0.0 45 491 78 518 0.09165 1.1e-005 245 3 M4537_1.02 E2F4 SGCGGGAARWTBVRR 2.1e0000 2.8e-003 -5.88 0.0 292 486 375 544 0.60082 1.2e-005 242 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 1.1e0000 1.4e-003 -6.54 0.0 80 480 140 586 0.16667 6.1e-006 239 3 M4612_1.02 CTCFL CCRSCAGGGGGCGCY 8.6e-003 1.2e-005 -11.37 0.0 172 486 227 478 0.35391 4.8e-008 242 3 M4698_1.02 HNF4A BTGRMCTTTGVMCYB 8.0e0000 1.1e-002 -4.53 0.0 142 486 207 561 0.29218 4.5e-005 242 3 M4850_1.02 (TCF15)_(Drosophila_melanogaster)_(DBD_0.70) TKTWRTNKBBDYDMCATSTGK 1.7e-003 2.4e-006 -12.96 0.0 36 480 80 542 0.07500 9.9e-009 239 3 M5308_1.02 BHLHE23 AMCATATGBY 1.0e-002 1.4e-005 -11.19 0.0 61 491 83 369 0.12424 5.6e-008 245 3 M5398_1.02 ERF ACCGGAAGTR 5.3e0000 7.2e-003 -4.93 0.0 417 491 495 545 0.84929 2.9e-005 245 3 M5425_1.02 ETV6 CCGGAASCGGAAGYR 7.1e-008 9.5e-011 -23.07 0.0 70 486 109 378 0.14403 3.9e-013 242 3 M5430_1.02 FIGLA WMCACCTGKW 4.3e0000 5.8e-003 -5.16 0.0 71 491 120 574 0.14460 2.4e-005 245 3 M5634_1.02 MNT VVCACGTGVH 1.9e0000 2.6e-003 -5.94 0.0 39 491 66 480 0.07943 1.1e-005 245 3 M5636_1.02 MSC AACAGCTGTT 2.2e-003 3.0e-006 -12.72 0.0 45 491 81 461 0.09165 1.2e-008 245 3 M5738_1.02 POU3F4 ATTWGCATA 7.8e0000 1.0e-002 -4.56 0.0 46 492 65 420 0.09350 4.3e-005 245 3 M5857_1.02 SPDEF AMCCGGATGTW 2.6e0000 3.5e-003 -5.66 0.0 72 490 96 429 0.14694 1.4e-005 244 3 M5979_1.02 ZNF75A TGTGGGAAAAGC 4.9e-008 6.6e-011 -23.43 0.0 63 489 128 519 0.12883 2.7e-013 244 3 M5981_1.02 ZSCAN4 TTTTCAGKGTGTGCA 6.3e0000 8.4e-003 -4.78 0.0 44 486 50 306 0.09053 3.5e-005 242 3 M6119_1.02 SPI1 RAAAAGAGGAAGTGV 2.0e-004 2.8e-007 -15.10 0.0 94 486 165 550 0.19342 1.1e-009 242 3 M6204_1.02 ELF2 TDNCAGGAAGTRRVT 3.7e-002 4.9e-005 -9.91 0.0 80 486 143 574 0.16461 2.0e-007 242 3 M6208_1.02 ELK3 VMCHGGAARTSC 4.0e-008 5.4e-011 -23.65 0.0 47 489 112 567 0.09611 2.2e-013 244 3 M6213_1.02 ERG ACCGGAARTSM 2.5e-004 3.3e-007 -14.91 0.0 48 490 97 528 0.09796 1.4e-009 244 3 M6221_1.02 ETS2 VMVGGAAGTKS 2.9e-003 3.9e-006 -12.46 0.0 76 490 146 599 0.15510 1.6e-008 244 3 M6222_1.02 ETV4 SAGGAAGY 3.9e0000 5.3e-003 -5.23 0.0 403 493 527 599 0.81744 2.2e-005 246 3 M6226_1.02 FEV CAGGAARTDA 6.9e0000 9.3e-003 -4.67 0.0 261 491 352 572 0.53157 3.8e-005 245 3 M6313_1.02 IRF8 GRGRAAVTGAAASYR 8.2e-001 1.1e-003 -6.81 0.0 110 486 179 583 0.22634 4.6e-006 242 3 M6316_1.02 TCF4 VCAGGTGCD 1.1e-001 1.5e-004 -8.82 0.0 58 492 105 552 0.11789 6.0e-007 245 3 M6330_1.02 MAFA STGCTGACBMYGCARYHTYCV 5.0e-004 6.8e-007 -14.20 0.0 114 480 201 580 0.23750 2.8e-009 239 3 M6336_1.02 MAZ RGGGDRGGGAGGGRGGG 5.7e-001 7.6e-004 -7.18 0.0 316 484 427 576 0.65289 3.2e-006 241 3 M6339_1.02 MECP2 YYCCGGS 9.5e-002 1.3e-004 -8.96 0.0 66 494 119 571 0.13360 5.2e-007 246 3 M6352_1.02 MYCN CCACGTGS 1.9e-001 2.6e-004 -8.24 0.0 49 493 84 497 0.09939 1.1e-006 246 3 M6381_1.02 NR0B1 YSTCCCMCKC 2.7e-001 3.7e-004 -7.91 0.0 63 491 117 595 0.12831 1.5e-006 245 3 M6402_1.02 OVOL1 KGTAACKGT 3.5e-005 4.8e-008 -16.86 0.0 84 492 152 542 0.17073 1.9e-010 245 3 M6436_1.02 PGR DACAGRNTGTTCY 7.2e-020 9.7e-023 -50.69 0.0 42 488 132 578 0.08607 4.0e-025 243 3 M6486_1.02 SPZ1 CGGCKGWWACMBYGGG 1.2e-021 1.7e-024 -54.74 0.0 75 485 186 547 0.15464 6.9e-027 242 3 M6499_1.02 RBPJ CGTGGGAAM 4.4e-002 5.9e-005 -9.73 0.0 64 492 122 594 0.13008 2.4e-007 245 3 M6559_1.02 ZNF589 CCMASGGKWWYWRCCS 1.1e-004 1.5e-007 -15.71 0.0 49 485 108 581 0.10103 6.2e-010 242 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).