# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 VKGGAACAGMAD MEME-1 VKGGAACAGMAD 1.8e-200 2.4e-203 -466.54 0.0 77 489 424 584 0.15746 1.0e-205 244 1 TCCYRCCTCWGRGCCTTTGCAC MEME-2 TCCYRCCTCWGRGCCTTTGCAC 6.3e-033 8.5e-036 -80.76 0.0 69 479 115 226 0.14405 3.5e-038 239 1 CCTGGAAYRCYCTTCC MEME-3 CCTGGAAYRCYCTTCC 1.1e-042 1.4e-045 -103.27 0.0 67 485 142 283 0.13814 5.8e-048 242 1 CAGMKGGAACAG MEME-4 CAGMKGGAACAG 2.6e-107 3.5e-110 -252.04 0.0 55 489 235 411 0.11247 1.4e-112 244 1 GGRRRGVAGGGARGAG MEME-5 GGRRRGVAGGGARGAG 1.2e-004 1.6e-007 -15.63 0.0 85 485 149 526 0.17526 6.7e-010 242 1 GCCTSRGGVCTTTGCA MEME-7 GCCTSRGGVCTTTGCA 4.3e-004 5.7e-007 -14.37 0.0 59 485 24 53 0.12165 2.4e-009 242 1 AGBKCCTGGAACAGCRTGGGAA MEME-8 AGBKCCTGGAACAGCRTGGGAA 3.4e-009 4.6e-012 -26.11 0.0 55 479 23 34 0.11482 1.9e-014 239 2 CBSTTCC DREME-1 CTSTTCC 2.7e-159 3.7e-162 -371.72 0.0 70 494 354 538 0.14170 1.5e-164 246 2 CCBGGAA DREME-2 CCTGGAA 5.3e-027 7.1e-030 -67.12 0.0 60 494 112 278 0.12146 2.9e-032 246 2 TRTGCAAA DREME-3 TGTGCAAA 7.0e-014 9.3e-017 -36.91 0.0 51 493 53 132 0.10345 3.8e-019 246 2 CTCWGAGC DREME-4 CTCTGAGC 3.5e-007 4.6e-010 -21.49 0.0 59 493 35 81 0.11968 1.9e-012 246 3 M0178_1.02 (ASCL2)_(Mus_musculus)_(DBD_0.98) NVCAGCTGBN 2.3e-001 3.1e-004 -8.08 0.0 73 491 128 575 0.14868 1.3e-006 245 3 M0198_1.02 (SOHLH2)_(Mus_musculus)_(DBD_0.84) NGYVCGTGCN 2.8e-002 3.7e-005 -10.20 0.0 35 491 75 561 0.07128 1.5e-007 245 3 M0212_1.02 (TCFL5)_(Mus_musculus)_(DBD_1.00) NBCDCGHGVN 1.5e-002 2.0e-005 -10.83 0.0 31 491 55 398 0.06314 8.1e-008 245 3 M0216_1.02 (NHLH2)_(Mus_musculus)_(DBD_1.00) NGCAGCTGYN 9.9e-005 1.3e-007 -15.84 0.0 69 491 138 583 0.14053 5.4e-010 245 3 M0398_1.02 (ZSCAN10)_(Mus_musculus)_(DBD_0.82) NGKRAGTGCNN 1.5e-001 2.0e-004 -8.54 0.0 124 490 202 588 0.25306 8.0e-007 244 3 M0433_1.02 (ZBTB12)_(Mus_musculus)_(DBD_1.00) NYCTAGAACN 5.7e-010 7.6e-013 -27.90 0.0 69 491 155 588 0.14053 3.1e-015 245 3 M1838_1.02 TFAP2A NHYDGCCYSAGGGCA 3.9e-002 5.2e-005 -9.86 0.0 70 486 124 550 0.14403 2.2e-007 242 3 M1841_1.02 AR GNACABNVTGTTCYY 6.7e-046 9.0e-049 -110.63 0.0 40 486 168 553 0.08230 3.7e-051 242 3 M1889_1.02 MAX RRGCACATGK 2.8e0000 3.7e-003 -5.60 0.0 75 491 111 491 0.15275 1.5e-005 245 3 M1927_1.02 (MYCL1)_(Mus_musculus)_(DBD_0.66) RCCACGTG 5.3e-001 7.0e-004 -7.26 0.0 83 493 123 493 0.16836 2.9e-006 246 3 M1955_1.02 STAT1 TTTCYRGGAAA 3.5e-003 4.7e-006 -12.27 0.0 48 490 92 518 0.09796 1.9e-008 244 3 M2273_1.02 E2F6 RGGCGGGARRV 3.7e-003 5.0e-006 -12.22 0.0 74 490 141 591 0.15102 2.0e-008 244 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 2.6e-004 3.5e-007 -14.86 0.0 84 488 159 586 0.17213 1.4e-009 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 9.2e-001 1.2e-003 -6.70 0.0 284 490 399 596 0.57959 5.1e-006 244 3 M2299_1.02 (MYF5)_(Mus_musculus)_(DBD_0.90) NRNRRCAGCTGSN 5.5e-002 7.3e-005 -9.52 0.0 56 488 107 572 0.11475 3.0e-007 243 3 M2305_1.02 NRF1 YGCGCABGCGC 1.7e-002 2.2e-005 -10.72 0.0 64 490 95 424 0.13061 9.0e-008 244 3 M2307_1.02 PRDM1 DRAAAGTGAAAGTGR 2.7e0000 3.6e-003 -5.64 0.0 102 486 160 561 0.20988 1.5e-005 242 3 M2390_1.02 EHF SAGGAAGK 9.1e-001 1.2e-003 -6.71 0.0 253 493 350 578 0.51318 5.0e-006 246 3 M4427_1.02 CTCF NYGGCCASCAGRKGGCRSYVB 7.4e-002 9.9e-005 -9.22 0.0 174 480 228 481 0.36250 4.2e-007 239 3 M4428_1.02 NR3C1 RGVACAYTBTGTYC 1.3e-036 1.7e-039 -89.29 0.0 47 487 167 547 0.09651 6.9e-042 243 3 M4453_1.02 BCL11A ADGRGGAASTGARAV 1.3e-006 1.8e-009 -20.15 0.0 104 486 197 586 0.21399 7.3e-012 242 3 M4462_1.02 GABPA VVCCGGAAGTG 6.0e0000 8.0e-003 -4.83 0.0 278 490 367 564 0.56735 3.3e-005 244 3 M4479_1.02 TCF12 VSAGCAGSTGB 2.0e-004 2.6e-007 -15.15 0.0 46 490 101 578 0.09388 1.1e-009 244 3 M4522_1.02 ELK4 CCGGAAGYGS 2.8e-003 3.7e-006 -12.51 0.0 285 491 400 577 0.58045 1.5e-008 245 3 M4525_1.02 TFAP2C NGCCYSAGGSCANDB 1.3e-001 1.8e-004 -8.63 0.0 76 486 131 556 0.15638 7.4e-007 242 3 M4532_1.02 MYC CCACGTGSYY 1.5e0000 2.0e-003 -6.20 0.0 75 491 118 522 0.15275 8.3e-006 245 3 M4604_1.02 ZNF263 RRGGAGGASGVVGRGGRGGRG 6.5e-001 8.7e-004 -7.04 0.0 70 480 126 584 0.14583 3.7e-006 239 3 M4612_1.02 CTCFL CCRSCAGGGGGCGCY 8.4e-002 1.1e-004 -9.09 0.0 168 486 223 490 0.34568 4.7e-007 242 3 M4850_1.02 (TCF15)_(Drosophila_melanogaster)_(DBD_0.70) TKTWRTNKBBDYDMCATSTGK 6.3e-003 8.4e-006 -11.69 0.0 24 480 58 532 0.05000 3.5e-008 239 3 M4971_1.02 (FERD3L)_(Drosophila_melanogaster)_(DBD_0.89) GTVACAGVTG 1.2e0000 1.7e-003 -6.40 0.0 137 491 212 586 0.27902 6.8e-006 245 3 M5308_1.02 BHLHE23 AMCATATGBY 6.7e-002 8.9e-005 -9.32 0.0 45 491 64 360 0.09165 3.6e-007 245 3 M5425_1.02 ETV6 CCGGAASCGGAAGYR 3.1e-007 4.1e-010 -21.61 0.0 68 486 108 389 0.13992 1.7e-012 242 3 M5430_1.02 FIGLA WMCACCTGKW 5.0e0000 6.6e-003 -5.01 0.0 63 491 108 574 0.12831 2.7e-005 245 3 M5627_1.02 MESP1 NVCAGGTGYD 9.6e0000 1.3e-002 -4.35 0.0 89 491 146 593 0.18126 5.3e-005 245 3 M5636_1.02 MSC AACAGCTGTT 2.4e-003 3.2e-006 -12.65 0.0 25 491 55 464 0.05092 1.3e-008 245 3 M5857_1.02 SPDEF AMCCGGATGTW 9.4e-002 1.3e-004 -8.98 0.0 80 490 112 435 0.16327 5.2e-007 244 3 M5979_1.02 ZNF75A TGTGGGAAAAGC 4.8e-006 6.4e-009 -18.87 0.0 57 489 112 508 0.11656 2.6e-011 244 3 M5981_1.02 ZSCAN4 TTTTCAGKGTGTGCA 8.6e0000 1.1e-002 -4.47 0.0 40 486 45 295 0.08230 4.8e-005 242 3 M6119_1.02 SPI1 RAAAAGAGGAAGTGV 1.9e-004 2.5e-007 -15.19 0.0 92 486 160 538 0.18930 1.0e-009 242 3 M6204_1.02 ELF2 TDNCAGGAAGTRRVT 3.5e-003 4.6e-006 -12.28 0.0 96 486 169 572 0.19753 1.9e-008 242 3 M6205_1.02 ELF3 GGSAAACAGGAARY 7.4e0000 9.9e-003 -4.61 0.0 45 487 82 568 0.09240 4.1e-005 243 3 M6208_1.02 ELK3 VMCHGGAARTSC 9.8e-007 1.3e-009 -20.46 0.0 33 489 86 570 0.06748 5.4e-012 244 3 M6213_1.02 ERG ACCGGAARTSM 3.6e-004 4.8e-007 -14.56 0.0 60 490 113 526 0.12245 2.0e-009 244 3 M6221_1.02 ETS2 VMVGGAAGTKS 1.7e-003 2.3e-006 -13.00 0.0 86 490 161 599 0.17551 9.3e-009 244 3 M6276_1.02 HINFP DMSNHMGCGGACGTTV 4.2e0000 5.6e-003 -5.18 0.0 267 485 236 358 0.55052 2.3e-005 242 3 M6313_1.02 IRF8 GRGRAAVTGAAASYR 3.2e0000 4.2e-003 -5.47 0.0 64 486 113 581 0.13169 1.7e-005 242 3 M6316_1.02 TCF4 VCAGGTGCD 1.6e-001 2.1e-004 -8.48 0.0 64 492 113 555 0.13008 8.5e-007 245 3 M6330_1.02 MAFA STGCTGACBMYGCAGYHTYCV 3.6e-006 4.7e-009 -19.17 0.0 40 480 98 579 0.08333 2.0e-011 239 3 M6348_1.02 MTF1 MGKGCCGTGYGCAAARS 1.3e0000 1.7e-003 -6.39 0.0 60 484 83 414 0.12397 7.0e-006 241 3 M6353_1.02 MYF6 GCAGSTG 8.4e-001 1.1e-003 -6.79 0.0 48 494 92 587 0.09717 4.6e-006 246 3 M6381_1.02 NR0B1 YSTCCCMCKC 8.5e-002 1.1e-004 -9.08 0.0 71 491 131 596 0.14460 4.6e-007 245 3 M6402_1.02 OVOL1 KGTAACKGT 9.4e-005 1.3e-007 -15.89 0.0 86 492 152 538 0.17480 5.1e-010 245 3 M6436_1.02 PGR DACAGRNTGTTCY 2.7e-018 3.6e-021 -47.07 0.0 34 488 113 573 0.06967 1.5e-023 243 3 M6486_1.02 SPZ1 CGGCKGWWACMBYGGG 3.0e-022 4.0e-025 -56.18 0.0 45 485 138 549 0.09278 1.7e-027 242 3 M6499_1.02 RBPJ CGTGGGAAM 5.8e-001 7.8e-004 -7.16 0.0 30 492 66 592 0.06098 3.2e-006 245 3 M6527_1.02 TWIST1 MCCCAGGTGK 5.2e0000 7.0e-003 -4.96 0.0 73 491 111 515 0.14868 2.9e-005 245 3 M6559_1.02 ZNF589 CCMASGGKWWYWRCCS 1.1e-002 1.5e-005 -11.09 0.0 65 485 124 578 0.13402 6.3e-008 242 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).