# WARNING: this file is not sorted! # db id alt consensus E-value adj_p-value log_adj_p-value bin_location bin_width total_width sites_in_bin total_sites p_success p-value mult_tests 1 RRCCAATSRGMR MEME-1 RRCCAATSRGMR 3.3e-069 4.5e-072 -164.28 0.0 173 489 385 514 0.35378 1.8e-074 244 1 YBHVGYCCCGCCCCYY MEME-2 YBHVGYCCCGCCCCYY 2.1e-052 2.9e-055 -125.58 0.0 245 485 490 598 0.50515 1.2e-057 242 1 CCYCYTYCCCTYCCBYYYCYTC MEME-3 CCYCYTYCCCTYCCBYYYCYTC 6.4e-002 8.7e-005 -9.36 0.0 95 479 153 529 0.19833 3.6e-007 239 2 CCAATVR DREME-1 CCAATSR 8.4e-070 1.1e-072 -165.66 0.0 238 494 421 479 0.48178 4.6e-075 246 2 CCGCCYH DREME-2 CCGCCCC 5.8e-025 7.9e-028 -62.41 0.0 236 494 413 580 0.47773 3.2e-030 246 2 CCARTCC DREME-3 CCAATCC 1.6e-003 2.2e-006 -13.03 0.0 174 494 106 190 0.35223 8.9e-009 246 2 CACBTC DREME-4 CACYTC 9.5e-002 1.3e-004 -8.96 0.0 305 495 303 414 0.61616 5.2e-007 247 3 M0395_1.02 (ZNF187)_(Mus_musculus)_(DBD_0.88) GKACTAAT 1.3e-002 1.7e-005 -10.96 0.0 109 493 177 556 0.22110 7.0e-008 246 3 M0405_1.02 (KLF7)_(Mus_musculus)_(DBD_1.00) DGGGCGKGGY 1.6e-017 2.2e-020 -45.26 0.0 177 491 334 600 0.36049 9.0e-023 245 3 M0443_1.02 (KLF12)_(Mus_musculus)_(DBD_1.00) DGGGCGKGGY 9.7e-012 1.3e-014 -31.96 0.0 179 491 319 600 0.36456 5.4e-017 245 3 M0608_1.02 MLL NNNRSCGNDN 6.3e-002 8.5e-005 -9.38 0.0 189 491 254 514 0.38493 3.5e-007 245 3 M0714_1.02 (ENSG00000235187)_(Mus_musculus)_(DBD_1.00) NDBCGGAARY 1.4e-002 1.9e-005 -10.85 0.0 251 491 371 599 0.51120 8.0e-008 245 3 M0890_1.02 LHX6 NYAATCAN 2.0e-010 2.7e-013 -28.93 0.0 197 493 328 581 0.39959 1.1e-015 246 3 M0892_1.02 EMX1 VYTAATKASB 1.1e-003 1.5e-006 -13.40 0.0 123 491 198 548 0.25051 6.2e-009 245 3 M0893_1.02 ZFHX2 NNTAATTANN 1.9e-003 2.5e-006 -12.88 0.0 135 491 204 525 0.27495 1.0e-008 245 3 M0894_1.02 LBX1 TTAATTAG 2.7e0000 3.7e-003 -5.61 0.0 123 493 177 535 0.24949 1.5e-005 246 3 M0900_1.02 SHOX NTAATTRV 2.1e-008 2.8e-011 -24.29 0.0 123 493 216 549 0.24949 1.2e-013 246 3 M0931_1.02 (LHX1)_(Mus_musculus)_(DBD_1.00) TAATTRNNN 4.3e-002 5.8e-005 -9.76 0.0 140 492 218 567 0.28455 2.4e-007 245 3 M0943_1.02 (OTP)_(Mus_musculus)_(DBD_1.00) NYTAATTR 8.1e-001 1.1e-003 -6.82 0.0 117 493 182 568 0.23732 4.4e-006 246 3 M0958_1.02 (LHX4)_(Mus_musculus)_(DBD_1.00) BYAATYW 3.2e-008 4.4e-011 -23.86 0.0 126 494 229 581 0.25506 1.8e-013 246 3 M0969_1.02 (LHX8)_(Mus_musculus)_(DBD_1.00) NYAATYANN 3.8e-013 5.1e-016 -35.21 0.0 134 492 256 580 0.27236 2.1e-018 245 3 M0975_1.02 (LHX5)_(Mus_musculus)_(DBD_1.00) TAATTRVNN 1.3e-003 1.8e-006 -13.23 0.0 128 492 210 569 0.26016 7.3e-009 245 3 M1025_1.02 (HOXD1)_(Mus_musculus)_(DBD_0.98) NBYVATYA 3.6e-006 4.9e-009 -19.14 0.0 145 493 242 570 0.29412 2.0e-011 246 3 M1871_1.02 (KLF2)_(Mus_musculus)_(DBD_0.95) DGGGYGKGGC 1.1e-012 1.5e-015 -34.10 0.0 241 491 398 598 0.49084 6.3e-018 245 3 M1890_1.02 NFYA AGVSYKCTGATTGGYBSR 3.7e-054 5.0e-057 -129.63 0.0 199 483 404 532 0.41201 2.1e-059 241 3 M1906_1.02 SP1 GGGGGMGGGGC 7.3e-027 9.9e-030 -66.79 0.0 238 490 434 600 0.48571 4.0e-032 244 3 M1970_1.02 NFIC TGCCAA 1.3e-011 1.7e-014 -31.70 0.0 209 495 354 599 0.42222 6.9e-017 247 3 M2270_1.02 DUX4 TAAYYYAATCA 1.6e0000 2.2e-003 -6.11 0.0 190 490 214 436 0.38776 9.1e-006 244 3 M2273_1.02 E2F6 RGGCGGGARRV 1.1e-002 1.5e-005 -11.08 0.0 206 490 316 598 0.42041 6.3e-008 244 3 M2275_1.02 ELF1 RRAVCMGGAAGTG 6.8e-002 9.2e-005 -9.29 0.0 258 488 365 578 0.52869 3.8e-007 243 3 M2277_1.02 FLI1 RCAGGAAGTGR 7.0e-002 9.5e-005 -9.26 0.0 250 490 361 589 0.51020 3.9e-007 244 3 M2301_1.02 NFYB VHMYBRRCCAATCAG 1.8e-054 2.4e-057 -130.37 0.0 204 486 418 548 0.41975 9.9e-060 242 3 M2314_1.02 SP2 SSSVRGRGGCGGGRC 1.0e-038 1.4e-041 -94.10 0.0 228 486 449 600 0.46914 5.6e-044 242 3 M2391_1.02 KLF5 DGGGHGGGGC 3.9e-016 5.3e-019 -42.09 0.0 241 491 409 599 0.49084 2.1e-021 245 3 M4459_1.02 EGR1 SBGCGKGGGCGGVGGSGSGS 2.0e-001 2.7e-004 -8.23 0.0 257 481 368 582 0.53430 1.1e-006 240 3 M4462_1.02 GABPA VVCCGGAAGTG 6.4e-005 8.6e-008 -16.26 0.0 282 490 408 583 0.57551 3.5e-010 244 3 M4473_1.02 PBX3 NBCRGCCAATSRGVR 1.6e-063 2.2e-066 -151.19 0.0 188 486 432 579 0.38683 9.1e-069 242 3 M4522_1.02 ELK4 CCGGAAGYGS 2.7e-006 3.7e-009 -19.42 0.0 311 491 447 586 0.63340 1.5e-011 245 3 M4537_1.02 E2F4 SGCGGGAARWTBVRR 3.8e-001 5.1e-004 -7.57 0.0 226 486 331 591 0.46502 2.1e-006 242 3 M5209_1.02 (SP5)_(Drosophila_melanogaster)_(DBD_0.93) GKGGGCGKRKC 6.2e-031 8.3e-034 -76.17 0.0 264 490 471 600 0.53878 3.4e-036 244 3 M5284_1.02 ALX3 BBTAATTRGY 7.6e-012 1.0e-014 -32.21 0.0 125 491 225 534 0.25458 4.2e-017 245 3 M5310_1.02 BSX BTAATBRS 2.9e-002 3.9e-005 -10.16 0.0 109 493 178 567 0.22110 1.6e-007 246 3 M5342_1.02 DLX4 NTAATTRB 3.7e-003 5.0e-006 -12.20 0.0 143 493 220 548 0.29006 2.0e-008 246 3 M5344_1.02 DLX6 NTAATTRB 2.1e-004 2.8e-007 -15.08 0.0 143 493 221 538 0.29006 1.1e-009 246 3 M5349_1.02 DUXA NTRAYBTAATCAN 7.8e0000 1.1e-002 -4.55 0.0 204 488 240 471 0.41803 4.4e-005 243 3 M5377_1.02 ELF4 AACCCGGAAGTR 1.8e-001 2.4e-004 -8.35 0.0 215 489 267 486 0.43967 9.7e-007 244 3 M5388_1.02 EMX2 VYTAATTAVB 5.2e-014 7.1e-017 -37.19 0.0 123 491 217 499 0.25051 2.9e-019 245 3 M5390_1.02 EN1 VBTAATTRSB 1.4e-022 1.8e-025 -56.96 0.0 183 491 328 542 0.37271 7.5e-028 245 3 M5394_1.02 EN2 NNTAATTRVN 2.4e-010 3.3e-013 -28.75 0.0 133 491 230 534 0.27088 1.3e-015 245 3 M5398_1.02 ERF ACCGGAAGTR 4.7e-005 6.3e-008 -16.58 0.0 279 491 389 558 0.56823 2.6e-010 245 3 M5414_1.02 ESX1 SNTAATTRRN 5.8e-014 7.8e-017 -37.09 0.0 123 491 233 548 0.25051 3.2e-019 245 3 M5420_1.02 ETV1 ACCGGAAGTD 9.1e-008 1.2e-010 -22.82 0.0 279 491 414 581 0.56823 5.0e-013 245 3 M5421_1.02 ETV2 AACCGGAAATR 6.2e0000 8.3e-003 -4.79 0.0 278 490 337 515 0.56735 3.4e-005 244 3 M5422_1.02 ETV3 ACCGGAAGTR 2.9e-004 3.9e-007 -14.77 0.0 261 491 368 561 0.53157 1.6e-009 245 3 M5427_1.02 EVX1 SVTAATYABB 1.6e-009 2.2e-012 -26.84 0.0 123 491 221 551 0.25051 9.0e-015 245 3 M5428_1.02 EVX2 VBTAATKABB 2.5e-012 3.4e-015 -33.31 0.0 123 491 230 552 0.25051 1.4e-017 245 3 M5480_1.02 GBX1 VSTAATTRGB 7.2e-016 9.7e-019 -41.48 0.0 125 491 227 507 0.25458 4.0e-021 245 3 M5481_1.02 GBX2 NYTAATTRSB 5.1e-014 6.9e-017 -37.21 0.0 143 491 248 520 0.29124 2.8e-019 245 3 M5502_1.02 GSX1 NBTAATKRSN 3.7e-002 5.0e-005 -9.89 0.0 143 491 218 556 0.29124 2.1e-007 245 3 M5503_1.02 GSX2 DYTAATKRSN 3.7e0000 5.1e-003 -5.29 0.0 143 491 207 554 0.29124 2.1e-005 245 3 M5518_1.02 HMX1 NNTTAATTGNT 1.9e-001 2.6e-004 -8.27 0.0 184 490 256 536 0.37551 1.0e-006 244 3 M5519_1.02 HMX2 NNTTAAKTGBT 6.3e-002 8.5e-005 -9.37 0.0 88 490 148 558 0.17959 3.5e-007 244 3 M5520_1.02 HMX3 BNTTAAKTGBY 4.9e-004 6.6e-007 -14.23 0.0 88 490 160 570 0.17959 2.7e-009 244 3 M5541_1.02 HOXB2 NNTAATKANN 6.2e-001 8.3e-004 -7.09 0.0 113 491 176 559 0.23014 3.4e-006 245 3 M5542_1.02 HOXB3 NYTAATKRNN 1.8e-002 2.5e-005 -10.61 0.0 123 491 196 560 0.25051 1.0e-007 245 3 M5543_1.02 HOXB5 NNTAATKRNN 9.4e0000 1.3e-002 -4.36 0.0 93 491 145 565 0.18941 5.2e-005 245 3 M5591_1.02 KLF13 CAAAAAGGGGCGTGKCAY 5.4e-009 7.2e-012 -25.65 0.0 189 483 230 397 0.39130 3.0e-014 241 3 M5592_1.02 KLF14 ARGKGGGCGTGGYM 3.9e-017 5.2e-020 -44.39 0.0 335 487 494 572 0.68789 2.2e-022 243 3 M5593_1.02 KLF16 GGGGGCGTGKC 4.4e-013 6.0e-016 -35.05 0.0 238 490 396 598 0.48571 2.4e-018 244 3 M5594_1.02 LBX2 CTBRANSTRATTA 8.2e-002 1.1e-004 -9.11 0.0 34 488 73 569 0.06967 4.6e-007 243 3 M5602_1.02 LHX9 YTAATTRN 5.5e-016 7.4e-019 -41.75 0.0 123 493 237 546 0.24949 3.0e-021 246 3 M5623_1.02 MEOX1 VSTAATTANS 3.0e-005 4.0e-008 -17.03 0.0 125 491 204 539 0.25458 1.6e-010 245 3 M5624_1.02 MEOX2 NSTAATTAWN 4.3e-005 5.9e-008 -16.65 0.0 123 491 206 554 0.25051 2.4e-010 245 3 M5631_1.02 MIXL1 NBTAATTRVN 1.5e-010 2.0e-013 -29.22 0.0 185 491 297 544 0.37678 8.3e-016 245 3 M5635_1.02 MNX1 KTTAATTRNH 1.1e-001 1.4e-004 -8.84 0.0 117 491 179 541 0.23829 5.9e-007 245 3 M5660_1.02 NFIA TTGGCANNDTGCCAR 4.0e-001 5.4e-004 -7.52 0.0 160 486 117 248 0.32922 2.2e-006 242 3 M5662_1.02 NFIB TTGGCAHNDTGCCAR 5.3e-001 7.1e-004 -7.25 0.0 160 486 123 263 0.32922 2.9e-006 242 3 M5664_1.02 NFIX TTGGCANNNNGCCAR 2.0e0000 2.7e-003 -5.92 0.0 164 486 181 412 0.33745 1.1e-005 242 3 M5672_1.02 NOTO NBTAATTARN 5.1e-004 6.8e-007 -14.20 0.0 123 491 195 535 0.25051 2.8e-009 245 3 M5771_1.02 RAX NYTAATTRRY 1.1e-008 1.5e-011 -24.91 0.0 123 491 210 528 0.25051 6.2e-014 245 3 M5772_1.02 RAX2 BTAATTRR 1.5e-012 2.0e-015 -33.85 0.0 125 493 229 542 0.25355 8.1e-018 246 3 M5807_1.02 SHOX2 YTAATTRR 1.1e-010 1.5e-013 -29.56 0.0 185 493 287 522 0.37525 5.9e-016 246 3 M5856_1.02 SP8 RGKGGGCGTGGY 1.2e-010 1.6e-013 -29.47 0.0 287 489 441 592 0.58691 6.5e-016 244 3 M5941_1.02 UNCX NTAATBBAATTAN 7.3e0000 9.8e-003 -4.62 0.0 112 488 150 485 0.22951 4.1e-005 243 3 M5944_1.02 VAX1 YTAATTAN 3.6e-001 4.8e-004 -7.63 0.0 115 493 179 559 0.23327 2.0e-006 246 3 M5945_1.02 VAX2 YTAATTAB 1.9e-005 2.5e-008 -17.49 0.0 117 493 202 566 0.23732 1.0e-010 246 3 M5949_1.02 VSX1 YTAATTAN 1.3e-007 1.7e-010 -22.49 0.0 123 493 209 537 0.24949 7.0e-013 246 3 M5977_1.02 ZNF740 GTGGGGGGGK 3.1e-007 4.1e-010 -21.61 0.0 325 491 462 582 0.66191 1.7e-012 245 3 M6123_1.02 (ZNF281)_(Mus_musculus)_(DBD_1.00) GRGKKGGGGGAGGGG 1.5e-002 2.1e-005 -10.79 0.0 344 486 470 585 0.70782 8.5e-008 242 3 M6157_1.02 BARX2 TYRWTAATKR 1.5e0000 2.0e-003 -6.21 0.0 215 491 266 497 0.43788 8.2e-006 245 3 M6173_1.02 CEBPG VAGATTGCMHAAT 4.5e0000 6.1e-003 -5.11 0.0 180 488 228 497 0.36885 2.5e-005 243 3 M6174_1.02 CEBPZ AGCCAATSAGH 1.9e-060 2.6e-063 -144.12 0.0 202 490 428 557 0.41224 1.1e-065 244 3 M6184_1.02 CUX1 RBRSBDATCGATSB 7.4e-007 1.0e-009 -20.72 0.0 139 487 222 520 0.28542 4.1e-012 243 3 M6189_1.02 DLX3 GMTAATTRSW 7.9e-003 1.1e-005 -11.45 0.0 123 491 176 488 0.25051 4.3e-008 245 3 M6191_1.02 E2F2 GGCGCGAAAC 6.1e-002 8.2e-005 -9.41 0.0 241 491 338 567 0.49084 3.3e-007 245 3 M6196_1.02 E2F7 WWDGGCGCGAAAM 5.9e0000 8.0e-003 -4.83 0.0 166 488 163 369 0.34016 3.3e-005 243 3 M6199_1.02 EGR2 DGVGTGGGCGG 5.7e-007 7.8e-010 -20.98 0.0 280 490 421 593 0.57143 3.2e-012 244 3 M6200_1.02 EGR3 WGAGTGGGYGT 6.2e-001 8.4e-004 -7.08 0.0 62 490 108 554 0.12653 3.4e-006 244 3 M6201_1.02 EGR4 GGSGGYRGGGM 1.2e-005 1.6e-008 -17.97 0.0 290 490 418 580 0.59184 6.4e-011 244 3 M6207_1.02 ELK1 RCCGGAAGT 3.9e-005 5.3e-008 -16.75 0.0 280 492 416 599 0.56911 2.2e-010 245 3 M6213_1.02 ERG ACCGGAARTSM 3.3e-002 4.5e-005 -10.01 0.0 278 490 362 535 0.56735 1.8e-007 244 3 M6221_1.02 ETS2 VMVGGAAGTKS 1.3e-002 1.8e-005 -10.92 0.0 248 490 368 599 0.50612 7.4e-008 244 3 M6240_1.02 FOXI1 RRCCAATCAVAR 8.0e-059 1.1e-061 -140.38 0.0 197 489 404 528 0.40286 4.4e-064 244 3 M6262_1.02 GFI1B WGCMGTGATTT 5.9e-001 8.0e-004 -7.14 0.0 128 490 192 550 0.26122 3.3e-006 244 3 M6263_1.02 GFI1 GCWSTGATTT 5.3e-003 7.1e-006 -11.85 0.0 233 491 334 566 0.47454 2.9e-008 245 3 M6269_1.02 HBP1 AYYCATTGA 1.2e-007 1.7e-010 -22.51 0.0 168 492 259 526 0.34146 6.8e-013 245 3 M6292_1.02 HOXA5 CATTAATYAR 1.4e-007 1.9e-010 -22.40 0.0 145 491 225 505 0.29532 7.7e-013 245 3 M6293_1.02 HOXA7 BCCAATCKATYGAKB 7.2e-001 9.7e-004 -6.93 0.0 120 486 180 540 0.24691 4.0e-006 242 3 M6295_1.02 HOXB1 CCATCMATCW 9.9e-001 1.3e-003 -6.62 0.0 149 491 175 432 0.30346 5.4e-006 245 3 M6296_1.02 HOXB6 KKCATMAATCAWY 2.4e0000 3.3e-003 -5.71 0.0 218 488 194 346 0.44672 1.4e-005 243 3 M6298_1.02 HOXB8 BMATTAATCAA 4.1e0000 5.6e-003 -5.19 0.0 100 490 109 370 0.20408 2.3e-005 244 3 M6303_1.02 HOXD4 TTAATTGW 3.0e0000 4.1e-003 -5.51 0.0 135 493 198 556 0.27383 1.7e-005 246 3 M6306_1.02 INSM1 TGTMAGGGGGCR 1.3e-001 1.8e-004 -8.63 0.0 221 489 264 467 0.45194 7.3e-007 244 3 M6324_1.02 KLF4 DGGGYGKGGC 5.9e-011 8.0e-014 -30.16 0.0 241 491 393 599 0.49084 3.3e-016 245 3 M6325_1.02 KLF6 GGGGGCKG 7.0e-008 9.4e-011 -23.09 0.0 177 493 301 598 0.35903 3.8e-013 246 3 M6333_1.02 MAFG MATGACT 6.8e0000 9.2e-003 -4.69 0.0 280 494 370 570 0.56680 3.7e-005 246 3 M6336_1.02 MAZ RGGGRGGGGAGGGRGGG 1.5e-001 2.1e-004 -8.48 0.0 334 484 462 593 0.69008 8.6e-007 241 3 M6347_1.02 MSX2 TAATTNK 2.2e0000 3.0e-003 -5.80 0.0 134 494 198 561 0.27126 1.2e-005 246 3 M6373_1.02 NFYC YAGCCAATSAGVGS 2.0e-058 2.7e-061 -139.47 0.0 203 487 441 580 0.41684 1.1e-063 243 3 M6380_1.02 NOBOX HTAATTRSY 6.0e-011 8.1e-014 -30.14 0.0 118 492 208 519 0.23984 3.3e-016 245 3 M6411_1.02 PAX8 BTVAYTSRMGYRKR 6.7e-001 9.1e-004 -7.00 0.0 191 487 283 583 0.39220 3.7e-006 243 3 M6412_1.02 PBX1 VHMATCAATCAAWYH 3.7e-002 5.0e-005 -9.90 0.0 198 486 271 523 0.40741 2.1e-007 242 3 M6413_1.02 PBX2 SMATCAATCAMWTYM 2.1e-002 2.8e-005 -10.49 0.0 134 486 200 524 0.27572 1.2e-007 242 3 M6415_1.02 PDX1 CTAATTACY 1.7e-005 2.4e-008 -17.56 0.0 124 492 179 460 0.25203 9.6e-011 245 3 M6419_1.02 PKNOX1 MATCARTCAMBYB 2.5e-002 3.4e-005 -10.28 0.0 98 488 161 546 0.20082 1.4e-007 243 3 M6440_1.02 PRRX2 YTAATTR 1.2e-006 1.7e-009 -20.21 0.0 124 494 197 508 0.25101 6.8e-012 246 3 M6472_1.02 SOX15 CWTTGTT 4.6e-003 6.3e-006 -11.98 0.0 120 494 201 584 0.24291 2.6e-008 246 3 M6482_1.02 SP3 VGVVGGGGGCGGGGCBRGSS 3.7e-027 5.0e-030 -67.46 0.0 255 481 459 600 0.53015 2.1e-032 240 3 M6515_1.02 TFDP1 AWWKRGCGGGAAAY 1.8e-002 2.4e-005 -10.64 0.0 201 487 275 521 0.41273 9.9e-008 243 3 M6525_1.02 TLX1 BGBYAAKRWGS 6.1e-004 8.2e-007 -14.01 0.0 162 490 262 587 0.33061 3.4e-009 244 3 M6534_1.02 VSX2 HDMGCTAATTA 2.5e-012 3.4e-015 -33.32 0.0 126 490 195 437 0.25714 1.4e-017 244 3 M6535_1.02 WT1 GMGGGGGCGKGGG 2.1e-003 2.8e-006 -12.78 0.0 348 488 486 597 0.71311 1.2e-008 243 3 M6537_1.02 YBX1 BSKGATTSSCY 1.1e-031 1.5e-034 -77.86 0.0 176 490 368 599 0.35918 6.3e-037 244 3 M6539_1.02 ZBTB7B CGGVGRRGGGGMGSRGGSGGGH 6.4e0000 8.7e-003 -4.75 0.0 361 479 464 563 0.75365 3.6e-005 239 3 M6552_1.02 ZNF148 KGVGKGGGGGAGGGG 6.5e-006 8.7e-009 -18.56 0.0 334 486 483 599 0.68724 3.6e-011 242 3 M6553_1.02 ZNF219 GDGGGGGGYGGA 2.2e-005 2.9e-008 -17.35 0.0 303 489 442 594 0.61963 1.2e-010 244 ## # Detailed descriptions of columns in this file: # # db: The name of the database (file name) that contains the motif. # id: A name for the motif that is unique in the motif database file. # alt: An alternate name of the motif that may be provided # in the motif database file. # consensus: A consensus sequence computed from the motif. # E-value: The expected number motifs that would have least one. # region as enriched for best matches to the motif as the reported region. # The E-value is the p-value multiplied by the number of motifs in the # input database(s). # adj_p-value: The probability that any tested region would be as enriched for # best matches to this motif as the reported region is. # By default the p-value is calculated by using the one-tailed binomial # test on the number of sequences with a match to the motif # that have their best match in the reported region, corrected for # the number of regions and score thresholds tested. # The test assumes that the probability that the best match in a sequence # falls in the region is the region width divided by the # number of places a motif # can align in the sequence (sequence length minus motif width plus 1). # When CentriMo is run in discriminative mode with a negative # set of sequences, the p-value of a region is calculated # using the Fisher exact test on the # enrichment of best matches in the positive sequences relative # to the negative sequences, corrected # for the number of regions and score thresholds tested. # The test assumes that the probability that the best match (if any) # falls into a given region # is the same for all positive and negative sequences. # log_adj_p-value: Log of adjusted p-value. # bin_location: Location of the center of the most enriched region. # bin_width: The width (in sequence positions) of the most enriched region. # A best match to the motif is counted as being in the region if the # center of the motif falls in the region. # total_width: The window maximal size which can be reached for this motif: # rounded(sequence length - motif length +1)/2 # sites_in_bin: The number of (positive) sequences whose best match to the motif # falls in the reported region. # Note: This number may be less than the number of # (positive) sequences that have a best match in the region. # The reason for this is that a sequence may have many matches that score # equally best. # If n matches have the best score in a sequence, 1/n is added to the # appropriate bin for each match. # total_sites: The number of sequences containing a match to the motif # above the score threshold. # p_success: The probability of falling in the enriched window: # bin width / total width # p-value: The uncorrected p-value before it gets adjusted to the # number of multiple tests to give the adjusted p-value. # mult_tests: This is the number of multiple tests (n) done for this motif. # It was used to correct the original p-value of a region for # multiple tests using the formula: # p' = 1 - (1-p)^n where p is the uncorrected p-value. # The number of multiple tests is the number of regions # considered times the number of score thresholds considered. # It depends on the motif length, sequence length, and the type of # optimizations being done (central enrichment, local enrichment, # score optimization).