******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.12.0 (Release date: Tue Jun 27 16:22:50 2017 -0700) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme-suite.org . This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme-suite.org . ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/REPIN1.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResultsDefaultMax/seqs-centered ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr16:4253961-4254461 1.0000 100 chr19:10332927-10333427 1.0000 100 chr6:32971004-32971504 1.0000 100 chr19:34501532-34502032 1.0000 100 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chr19:39341652-39342152 1.0000 100 chr20:33401339-33401839 1.0000 100 chr15:101724042-10172454 1.0000 100 chr5:149755386-149755886 1.0000 100 chr11:62841286-62841786 1.0000 100 chr1:206612156-206612656 1.0000 100 chr1:225998873-225999373 1.0000 100 chr3:183107272-183107772 1.0000 100 chr7:129054701-129055201 1.0000 100 chr19:43575749-43576249 1.0000 100 chr11:59557580-59558080 1.0000 100 chr12:109477334-10947783 1.0000 100 chr14:54818832-54819332 1.0000 100 chr19:58327005-58327505 1.0000 100 chr5:139341763-139342263 1.0000 100 chr20:58650922-58651422 1.0000 100 chr14:35826311-35826811 1.0000 100 chr22:20495983-20496483 1.0000 100 chr10:72354566-72355066 1.0000 100 chr20:24992264-24992764 1.0000 100 chr15:68277402-68277902 1.0000 100 chr19:44259443-44259943 1.0000 100 chr10:13298621-13299121 1.0000 100 chr19:36837855-36838355 1.0000 100 chr5:148825829-148826329 1.0000 100 chr17:32341936-32342436 1.0000 100 chr1:36255917-36256417 1.0000 100 chr1:109484058-109484558 1.0000 100 chr16:3183985-3184485 1.0000 100 chr17:59209678-59210178 1.0000 100 chr19:41376159-41376659 1.0000 100 chr14:22982638-22983138 1.0000 100 chr6:3231621-3232121 1.0000 100 chr22:32472788-32473288 1.0000 100 chr5:181218520-181219020 1.0000 100 chr1:93078872-93079372 1.0000 100 chr16:30874977-30875477 1.0000 100 chr10:117541472-11754197 1.0000 100 chr6:79078056-79078556 1.0000 100 chr20:52972214-52972714 1.0000 100 chr17:45148393-45148893 1.0000 100 chr19:37594249-37594749 1.0000 100 chrX:73944035-73944535 1.0000 100 chr19:1383510-1384010 1.0000 100 chr21:39313556-39314056 1.0000 100 chr1:44213164-44213664 1.0000 100 chr12:54188168-54188668 1.0000 100 chr19:39411901-39412401 1.0000 100 chr19:17337039-17337539 1.0000 100 chr11:47578724-47579224 1.0000 100 chrUn_KI270467v1:3122-36 1.0000 100 chr19:35947339-35947839 1.0000 100 chr12:12266976-12267476 1.0000 100 chrUn_KI270467v1:2070-25 1.0000 100 chr19:36916386-36916886 1.0000 100 chr10:93702413-93702913 1.0000 100 chr1:235688752-235689252 1.0000 100 chr6:131628047-131628547 1.0000 100 chr7:102572306-102572806 1.0000 100 chr19:37655818-37656318 1.0000 100 chr5:150459727-150460227 1.0000 100 chr19:40556267-40556767 1.0000 100 chr1_KI270713v1_random:2 1.0000 100 chr6:24774894-24775394 1.0000 100 chr19:37371123-37371623 1.0000 100 chr12:8949986-8950486 1.0000 100 chr19:44207464-44207964 1.0000 100 chr1:241357387-241357887 1.0000 100 chr12:117189352-11718985 1.0000 100 chr1:183471815-183472315 1.0000 100 chr19:35643410-35643910 1.0000 100 chr12:47080555-47081055 1.0000 100 chr19:41310147-41310647 1.0000 100 chrUn_KI270466v1:187-687 1.0000 100 chr1:37989799-37990299 1.0000 100 chr19:36488967-36489467 1.0000 100 chr15:65610888-65611388 1.0000 100 chr19:44164465-44164965 1.0000 100 chr1:63523036-63523536 1.0000 100 chr2:235741461-235741961 1.0000 100 chr10:23411313-23411813 1.0000 100 chr6:41318730-41319230 1.0000 100 chr1:155244209-155244709 1.0000 100 chr8:28514878-28515378 1.0000 100 chrUn_KI270467v1:2907-34 1.0000 100 chr12:1085293-1085793 1.0000 100 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/REPIN1.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResultsDefaultMax/seqs-centered -oc /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/REPIN1.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResultsDefaultMax/meme_out -mod zoops -nmotifs 3 -minw 5 -maxw 50 -bfile /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/REPIN1.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResultsDefaultMax/background -dna -revcomp -nostatus model: mod= zoops nmotifs= 3 evt= inf object function= E-value of product of p-values width: minw= 5 maxw= 50 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 600 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 60000 N= 600 shuffle= -1 strands: + - sample: seed= 0 ctfrac= -1 maxwords= -1 Letter frequencies in dataset: A 0.214 C 0.286 G 0.286 T 0.214 Background letter frequencies (from /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/REPIN1.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResultsDefaultMax/background): A 0.208 C 0.292 G 0.292 T 0.208 ******************************************************************************** ******************************************************************************** MOTIF TATTATTATTDTTWTT MEME-1 width = 16 sites = 111 llr = 1691 E-value = 2.2e-317 ******************************************************************************** -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 Description -------------------------------------------------------------------------------- Simplified A 161:51:7:14::51: pos.-specific C ::2:::::1:::1:1: probability G :2::2112::31:2:: matrix T 918a39919849938a bits 2.3 * 2.0 * * * 1.8 * * * * * * 1.6 * * ** * ** * Relative 1.4 * ** ** ** ** * Entropy 1.1 * ** ** ** ** ** (22.0 bits) 0.9 **** ***** ** ** 0.7 ************* ** 0.5 **************** 0.2 **************** 0.0 ---------------- Multilevel TATTATTATTATTATT consensus G T T T sequence G G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr10:23411313-23411813 - 51 2.45e-11 CCAGAAATAT TATTATTATTATTATT ATTGTTGTTG chr1:241357387-241357887 + 83 2.45e-11 GCAGATGATt tattattattattatt at chr1:235688752-235689252 - 36 2.45e-11 TTATTATTAT TATTATTATTATTATT ATTTGAGACG chr1:36255917-36256417 + 74 2.45e-11 CTGCCTGGat tattattattattatt attgttatta chr3:183107272-183107772 + 39 2.45e-11 gttttgtttt tattattattattatt attattattt chr5:149755386-149755886 + 13 2.45e-11 TTGTTGTTGt tattattattattatt gttattatta chr1:44487450-44487950 - 26 2.45e-11 TTATTATTAT TATTATTATTATTATT ATTTTAGTAG chr19:43682205-43682705 - 24 2.45e-11 TTATTATTAT TATTATTATTATTATT ATTTTGAGAC chr19:34478445-34478945 + 3 2.45e-11 at tattattattattatt attCTGgagg chr3:14764280-14764780 + 2 2.45e-11 t tattattattattatt attattatta chr19:50356775-50357275 - 5 2.45e-11 GGATCTTTAC TATTATTATTATTATT ATTT chr6:7250761-7251261 + 7 2.45e-11 GGtttt tattattattattatt attattacag chr2:61136737-61137237 - 58 2.45e-11 GCCTCATTAT TATTATTATTATTATT ATCGTTGTTG chr19:38954718-38955218 + 3 2.45e-11 at tattattattattatt attattattt chr22:29602720-29603220 - 46 2.45e-11 TTATTATTGT TATTATTATTATTATT AATTATTATT chr17:48595521-48596021 + 68 2.45e-11 ttgttgttgt tattattattattatt atcatcatca chr8:65731762-65732262 + 5 2.45e-11 tcta tattattattattatt attattgttg chr19:13727312-13727812 - 45 2.45e-11 TTATTATTAT TATTATTATTATTATT ATTGTTATTA chr6:27603518-27604018 + 76 2.45e-11 gcgcccggcc tattattattattatt attattgtt chr1:19642506-19643006 - 30 2.45e-11 TTGTTGTTGT TATTATTATTATTATT AGAGACAGAA chr8:37538045-37538545 - 52 2.45e-11 CCAGGATTGT TATTATTATTATTATT TGGTTTGTTT chr16:40589-41089 - 76 2.45e-11 ATTATTATT TATTATTATTATTATT TTTGAGATGG chr17:18363685-18364185 + 56 4.91e-11 GCAGACACTT TATTATTATTATTTTT GTTAtttttt chr1:155244209-155244709 - 2 9.09e-11 TCACCATTAT TATTATTATTGTTATT A chr2:235741461-235741961 + 30 9.09e-11 TTAAGCACTt tattattattgttatt attattattg chr1_KI270713v1_random:2 + 60 9.09e-11 ttatcattat tattattattgttatt attattattg chr19:35881936-35882436 - 19 9.09e-11 ATTTATTTTT TATTTTTATTTTTATT TTTAGACAGG chr12:112942521-11294302 + 78 9.09e-11 ttgttgtttc tattattattgttatt attatta chr12:1085293-1085793 + 52 1.25e-10 CCTGGCCCgt tattattattattgtt gttgttgttg chr6:144482120-144482620 + 75 1.25e-10 AGAGGTATGC tattattattattgtt gttattatta chr21:31582137-31582637 - 14 1.25e-10 CTTGTGCTGT TATTATTATTATTGTT ATTGTTATTA chr16:24970657-24971157 + 12 1.25e-10 ttgttctgct tattattatttttgtt tgtttttttg chr3:187744894-187745394 - 24 1.25e-10 GTTATGTATT TATTATTATTATTGTT GTCTTTGAGT chr19:40556267-40556767 + 44 2.36e-10 tattgttact tattgttatttttatt gttactgttt chr14:54818832-54819332 - 76 2.36e-10 TATTATTGA TATTGTTATTATTATT ACCTTGCCAG chr19:3047348-3047848 + 15 2.36e-10 taatacttac tattgttattattatt attactaGCT chr15:73738476-73738976 - 13 2.36e-10 TTTCTTTTTT TATTTTTATTTTTTTT ATTTTTGAGA chr1:226790505-226791005 - 85 2.36e-10 . TATTGTTATTATTATT TTCAGACAGG chr19:16292326-16292826 + 83 2.36e-10 atttatttgt tgttattattattatt at chr12:117189352-11718985 - 49 3.36e-10 TCATTGTCAT TATTATTATTGTTGTT GTTGTTACAA chr19:40508804-40509304 + 57 3.36e-10 gagttttttt TATTATTATTGTTGTT GTTTATTGCT chr20:1469724-1470224 - 2 1.32e-09 GCAGTGGTAG TGTTGTTATTATTATT A chr1:26329828-26330328 - 84 1.32e-09 T TATTATTGTTGTTATT GTTATCATGA chr1:11297705-11298205 + 37 2.98e-09 CTATTACTTT TACTATTAttgttttt tgtttttttg chr17:43574902-43575402 + 14 3.33e-09 atgcaccctt tattattattattgct attgtttaat chr5:174327120-174327620 + 57 5.62e-09 TGTCattatg tgttattactattatt gtcatcataa chr17:7616403-7616903 - 35 5.62e-09 GCCGGGCCAC TATTATTATTATTTGT TGTTGTTGTT chr1:50978972-50979472 - 27 6.34e-09 GGTTGTTTTT TGTTTTTGTTTTTATT TGGTGGTGGG chr19:58278888-58279388 - 62 7.94e-09 CCGCCGTCGT TATTGTTGTTATTGTT ACCTGAAGCC chr16:30408586-30409086 + 24 9.04e-09 ATGGCtcttt tattattactgttgtt attgtttgag chr1:28648566-28649066 + 49 1.16e-08 ATTCTGTGTG TGTTTTTTTTTTTTTT TAGAGGCTGC chr19:41376159-41376659 + 77 1.31e-08 cggtccttgt tgctgttattattatt ggctatta chr12:120533965-12053446 - 47 1.45e-08 TTTGTTTTGG TTTTGTTTTTTTTATT TCCTCCCCCA chr6:27214821-27215321 - 64 1.79e-08 ACCCGCTTTT TGTTTTTGTTTTTGTT TTTTAATGAG chr13:46551297-46551797 + 56 1.79e-08 TACTTTCATt tattattattgtcgtt attattatGA chr17:75368277-75368777 + 48 1.79e-08 gtcaggcGTT TGtttttttttttgtt gttttttttt chr5:150459727-150460227 + 75 2.04e-08 agtgtagatt tattattatcgttgtt gttgttgttg chr6:2634300-2634800 - 41 2.04e-08 CCGTAAGCTC TGTTATTATTATCTTT TGATTTATAA chr19:40719213-40719713 + 79 2.32e-08 atgaggtaga tacttttttttttttt ctgaga chr21:36122987-36123487 - 39 2.84e-08 TGGCTTCATA TTTTTTTATTATTTAT TTATTTATTT chr12:8949986-8950486 + 69 3.92e-08 CCTTGGGGTG AATTATTATTGTTACT GTTATCTCTG chr6:44247016-44247516 + 29 4.36e-08 GCTGTATTCG TGTTGTTTTTGTTTTT TTCTGTCCTT chr22:32472788-32473288 - 81 6.52e-08 TTTT TGTTGTTGTTGTTGTT TGAGATGGAG chr16:3183985-3184485 + 38 6.52e-08 CCCTCtgttt tgttgttgttgttgtt gtttttTGAC chr19:38962006-38962506 - 3 8.80e-08 GCCAAACTCC AATTATTATTTATTTT TT chr12:54051953-54052453 - 7 1.57e-07 CGAAAAGTCG TAATGTGATTTTTTTT CCCTCT chr6:135030492-135030992 - 58 1.71e-07 CACTACTCTT TATTGTTATTTTTCCT CTTTATTATT chr15:71780260-71780760 - 59 1.71e-07 TTTCTTTTGG TGTTTTTGTTTGTTTT TTTAGTTGTA chr1:233293988-233294488 + 79 1.89e-07 gtaaatctgg tactattactttttct catttt chr1:151012476-151012976 + 83 1.89e-07 ttggttacga tattattctcattttt tt chr5:160008628-160009128 - 25 2.27e-07 TTTATTTATT TATTTATTTATTTATT TTTGAGACAG chr19:40567067-40567567 - 33 2.27e-07 TTTATTTATT TATTTATTTATTTATT TTTGAGACAG chr6:42565310-42565810 + 45 2.71e-07 GGGTGTGttt tgttgttgtttgtttt tgtttttgag chr7:114085831-114086331 - 12 3.53e-07 TACTTTGCGT TGTTATTGTCGTTGTT GTTGTTGATA chr14:32134462-32134962 - 54 3.53e-07 TGAGACATTG TGATGATATTTTTATT TCAAACAAGA chr1:232670018-232670518 - 47 4.19e-07 AAGCTGCGAG AGTTGTTACTGTTATT GATGATGGTA chr19:44259443-44259943 + 23 4.54e-07 gcccagctaa tttttgtatttttagt agagacgggg chr19:39033051-39033551 - 57 4.54e-07 GCCCAGCTAA TTTTTGTATTTTTAGT AGAGACGGGG chr1:236089906-236090406 + 85 4.54e-07 gtccggctaa tttttgtatttttagt chr19:38243750-38244250 - 11 4.95e-07 TGTGAATTGG TTTTATTTTATTTTAT TTCTTTGTTT chr1:155193878-155194378 - 64 4.95e-07 ACGCTCGGCT AATTTTTGTAGTTTTT AGTAGAGACG chr12:47080555-47081055 + 3 5.85e-07 CC TTTTTttcttttttct ctcttctcct chr1:146035622-146036122 - 51 1.19e-06 TGGTGAGCGA TTTCTTTATTTGTGTT TTTCTACATT chr19:1442273-1442773 - 48 1.19e-06 CTGTTTATCT TACTTTTGCATTTTTT TTCCAACTTT chr1:67850428-67850928 + 83 1.50e-06 aatacatggt agctcttattattATT TC chr19:44212611-44213111 - 11 1.50e-06 CAGTAACGAC TATCTTTATTGCTATT TTAAAGATGA chr19:36528785-36529285 + 45 1.50e-06 TGAGTCCCTG TGTTAGGACTGTTATT GTGTGACTGT chr1:30488250-30488750 - 6 1.50e-06 TCATTACCAT TACTATTACCATTACT ATTAC chr19:48645976-48646476 + 59 1.88e-06 cCGTGGTGTT ATTTAATTTTGTTGTT GGGCTGGGGG chrUn_KI270467v1:2907-34 + 29 2.02e-06 ataatttggg tactttgatattttat gtacagtatg chrUn_KI270466v1:187-687 + 55 2.02e-06 atattttgtg tactttgatattttat gtacagcata chrUn_KI270467v1:2070-25 + 33 2.02e-06 atattttggg tactttgatattttat gtacagtatg chrUn_KI270467v1:3122-36 + 65 2.02e-06 atattttggg tactttgatattttat ggacagtata chr12:70242753-70243253 - 38 2.18e-06 TTCGTGTTTG TGTTTGTGTTTGTGTT GGACACCCCC chr19:34218154-34218654 + 84 2.18e-06 TGCTGTGGGG TTTTGTGGTTTGTTTT C chr11:62841286-62841786 - 52 2.51e-06 AGCTAAATAG TTATGTTCTTGTTGTT TGAGTTGGAT chr1:51519416-51519916 - 50 2.89e-06 TATAAAGTGC CATTATTATTTTCTAT CATTATCTCA chr5:149449008-149449508 - 3 3.10e-06 TCTGTTAAGG TGACATTATTAATATT AT chr10:45564504-45565004 - 49 3.32e-06 GTCATATTAC TGTTATTGTCGTCGTT GTTGTTGTTT chr17:8226686-8227186 - 79 4.07e-06 GTGGCT TTTTTTTGTGTGTGTT TTGTTTTCTG chr19:35535955-35536455 - 52 4.36e-06 TAAGGGGAGA TAATAGTACTTTTCTT AGAGGGTTGT chr17:8173083-8173583 - 46 5.66e-06 TTTGCAGTCT TGCTATTGCTGTTTGT CTATTTTGCA chr1:61692230-61692730 - 55 6.05e-06 CTCTTTCTCT TTCTTTTTCTTTCTTT CTTTCTCTCT chr5:112160615-112161115 + 73 6.45e-06 GGTGCGAGCT TGCTGTGGTTTTTGCT CTGGGTCCTC chr5:38783078-38783578 + 4 7.32e-06 GGC TATTGTTGCTGGTGCT TCTGCAAGAG chr17:58631420-58631920 - 6 7.79e-06 GTCTGAGTAG TTCTGGGTTTTTTTTT TTTTC chr5:148825829-148826329 + 1 8.82e-06 . TTCTGTGTTTGTTTCT GGCCGCGTTT chr3:4987101-4987601 + 49 1.13e-05 AACCTAGAAG TATCATTAtgggtact attacaattc chr1:146387203-146387703 + 61 1.13e-05 gtggcagggc agatattatggttact gaaatgcctt chr17:7484227-7484727 + 42 1.35e-05 GGAACCCGGT TACTTATTTATTCGTT ACCCTTTTTC chr1:148402448-148402948 + 56 3.08e-05 GAGGGGTGTG AGCTTATACTTatatt tatctggcag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:23411313-23411813 2.5e-11 50_[-1]_34 chr1:241357387-241357887 2.5e-11 82_[+1]_2 chr1:235688752-235689252 2.5e-11 35_[-1]_49 chr1:36255917-36256417 2.5e-11 73_[+1]_11 chr3:183107272-183107772 2.5e-11 38_[+1]_46 chr5:149755386-149755886 2.5e-11 12_[+1]_72 chr1:44487450-44487950 2.5e-11 25_[-1]_59 chr19:43682205-43682705 2.5e-11 23_[-1]_61 chr19:34478445-34478945 2.5e-11 2_[+1]_82 chr3:14764280-14764780 2.5e-11 1_[+1]_83 chr19:50356775-50357275 2.5e-11 4_[-1]_80 chr6:7250761-7251261 2.5e-11 6_[+1]_78 chr2:61136737-61137237 2.5e-11 57_[-1]_27 chr19:38954718-38955218 2.5e-11 2_[+1]_82 chr22:29602720-29603220 2.5e-11 45_[-1]_39 chr17:48595521-48596021 2.5e-11 67_[+1]_17 chr8:65731762-65732262 2.5e-11 4_[+1]_80 chr19:13727312-13727812 2.5e-11 44_[-1]_40 chr6:27603518-27604018 2.5e-11 75_[+1]_9 chr1:19642506-19643006 2.5e-11 29_[-1]_55 chr8:37538045-37538545 2.5e-11 51_[-1]_33 chr16:40589-41089 2.5e-11 75_[-1]_9 chr17:18363685-18364185 4.9e-11 55_[+1]_29 chr1:155244209-155244709 9.1e-11 1_[-1]_83 chr2:235741461-235741961 9.1e-11 29_[+1]_55 chr1_KI270713v1_random:2 9.1e-11 59_[+1]_25 chr19:35881936-35882436 9.1e-11 18_[-1]_66 chr12:112942521-11294302 9.1e-11 77_[+1]_7 chr12:1085293-1085793 1.3e-10 51_[+1]_33 chr6:144482120-144482620 1.3e-10 74_[+1]_10 chr21:31582137-31582637 1.3e-10 13_[-1]_71 chr16:24970657-24971157 1.3e-10 11_[+1]_73 chr3:187744894-187745394 1.3e-10 23_[-1]_61 chr19:40556267-40556767 2.4e-10 43_[+1]_41 chr14:54818832-54819332 2.4e-10 75_[-1]_9 chr19:3047348-3047848 2.4e-10 14_[+1]_70 chr15:73738476-73738976 2.4e-10 12_[-1]_72 chr1:226790505-226791005 2.4e-10 84_[-1] chr19:16292326-16292826 2.4e-10 82_[+1]_2 chr12:117189352-11718985 3.4e-10 48_[-1]_36 chr19:40508804-40509304 3.4e-10 56_[+1]_28 chr20:1469724-1470224 1.3e-09 1_[-1]_83 chr1:26329828-26330328 1.3e-09 83_[-1]_1 chr1:11297705-11298205 3e-09 36_[+1]_48 chr17:43574902-43575402 3.3e-09 13_[+1]_71 chr5:174327120-174327620 5.6e-09 56_[+1]_28 chr17:7616403-7616903 5.6e-09 34_[-1]_50 chr1:50978972-50979472 6.3e-09 26_[-1]_58 chr19:58278888-58279388 7.9e-09 61_[-1]_23 chr16:30408586-30409086 9e-09 23_[+1]_61 chr1:28648566-28649066 1.2e-08 48_[+1]_36 chr19:41376159-41376659 1.3e-08 76_[+1]_8 chr12:120533965-12053446 1.4e-08 46_[-1]_38 chr6:27214821-27215321 1.8e-08 63_[-1]_21 chr13:46551297-46551797 1.8e-08 55_[+1]_29 chr17:75368277-75368777 1.8e-08 47_[+1]_37 chr5:150459727-150460227 2e-08 74_[+1]_10 chr6:2634300-2634800 2e-08 40_[-1]_44 chr19:40719213-40719713 2.3e-08 78_[+1]_6 chr21:36122987-36123487 2.8e-08 38_[-1]_46 chr12:8949986-8950486 3.9e-08 68_[+1]_16 chr6:44247016-44247516 4.4e-08 28_[+1]_56 chr22:32472788-32473288 6.5e-08 80_[-1]_4 chr16:3183985-3184485 6.5e-08 37_[+1]_47 chr19:38962006-38962506 8.8e-08 2_[-1]_82 chr12:54051953-54052453 1.6e-07 6_[-1]_78 chr6:135030492-135030992 1.7e-07 57_[-1]_27 chr15:71780260-71780760 1.7e-07 58_[-1]_26 chr1:233293988-233294488 1.9e-07 78_[+1]_6 chr1:151012476-151012976 1.9e-07 82_[+1]_2 chr5:160008628-160009128 2.3e-07 24_[-1]_60 chr19:40567067-40567567 2.3e-07 32_[-1]_52 chr6:42565310-42565810 2.7e-07 44_[+1]_40 chr7:114085831-114086331 3.5e-07 11_[-1]_73 chr14:32134462-32134962 3.5e-07 53_[-1]_31 chr1:232670018-232670518 4.2e-07 46_[-1]_38 chr19:44259443-44259943 4.5e-07 22_[+1]_62 chr19:39033051-39033551 4.5e-07 56_[-1]_28 chr1:236089906-236090406 4.5e-07 84_[+1] chr19:38243750-38244250 5e-07 10_[-1]_74 chr1:155193878-155194378 5e-07 63_[-1]_21 chr12:47080555-47081055 5.9e-07 2_[+1]_82 chr1:146035622-146036122 1.2e-06 50_[-1]_34 chr19:1442273-1442773 1.2e-06 47_[-1]_37 chr1:67850428-67850928 1.5e-06 82_[+1]_2 chr19:44212611-44213111 1.5e-06 10_[-1]_74 chr19:36528785-36529285 1.5e-06 44_[+1]_40 chr1:30488250-30488750 1.5e-06 5_[-1]_79 chr19:48645976-48646476 1.9e-06 58_[+1]_26 chrUn_KI270467v1:2907-34 2e-06 28_[+1]_56 chrUn_KI270466v1:187-687 2e-06 54_[+1]_30 chrUn_KI270467v1:2070-25 2e-06 32_[+1]_52 chrUn_KI270467v1:3122-36 2e-06 64_[+1]_20 chr12:70242753-70243253 2.2e-06 37_[-1]_47 chr19:34218154-34218654 2.2e-06 83_[+1]_1 chr11:62841286-62841786 2.5e-06 51_[-1]_33 chr1:51519416-51519916 2.9e-06 49_[-1]_35 chr5:149449008-149449508 3.1e-06 2_[-1]_82 chr10:45564504-45565004 3.3e-06 48_[-1]_36 chr17:8226686-8227186 4.1e-06 78_[-1]_6 chr19:35535955-35536455 4.4e-06 51_[-1]_33 chr17:8173083-8173583 5.7e-06 45_[-1]_39 chr1:61692230-61692730 6e-06 54_[-1]_30 chr5:112160615-112161115 6.4e-06 72_[+1]_12 chr5:38783078-38783578 7.3e-06 3_[+1]_81 chr17:58631420-58631920 7.8e-06 5_[-1]_79 chr5:148825829-148826329 8.8e-06 [+1]_84 chr3:4987101-4987601 1.1e-05 48_[+1]_36 chr1:146387203-146387703 1.1e-05 60_[+1]_24 chr17:7484227-7484727 1.3e-05 41_[+1]_43 chr1:148402448-148402948 3.1e-05 55_[+1]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TATTATTATTDTTWTT width=16 seqs=111 chr10:23411313-23411813 ( 51) TATTATTATTATTATT 1 chr1:241357387-241357887 ( 83) TATTATTATTATTATT 1 chr1:235688752-235689252 ( 36) TATTATTATTATTATT 1 chr1:36255917-36256417 ( 74) TATTATTATTATTATT 1 chr3:183107272-183107772 ( 39) TATTATTATTATTATT 1 chr5:149755386-149755886 ( 13) TATTATTATTATTATT 1 chr1:44487450-44487950 ( 26) TATTATTATTATTATT 1 chr19:43682205-43682705 ( 24) TATTATTATTATTATT 1 chr19:34478445-34478945 ( 3) TATTATTATTATTATT 1 chr3:14764280-14764780 ( 2) TATTATTATTATTATT 1 chr19:50356775-50357275 ( 5) TATTATTATTATTATT 1 chr6:7250761-7251261 ( 7) TATTATTATTATTATT 1 chr2:61136737-61137237 ( 58) TATTATTATTATTATT 1 chr19:38954718-38955218 ( 3) TATTATTATTATTATT 1 chr22:29602720-29603220 ( 46) TATTATTATTATTATT 1 chr17:48595521-48596021 ( 68) TATTATTATTATTATT 1 chr8:65731762-65732262 ( 5) TATTATTATTATTATT 1 chr19:13727312-13727812 ( 45) TATTATTATTATTATT 1 chr6:27603518-27604018 ( 76) TATTATTATTATTATT 1 chr1:19642506-19643006 ( 30) TATTATTATTATTATT 1 chr8:37538045-37538545 ( 52) TATTATTATTATTATT 1 chr16:40589-41089 ( 76) TATTATTATTATTATT 1 chr17:18363685-18364185 ( 56) TATTATTATTATTTTT 1 chr1:155244209-155244709 ( 2) TATTATTATTGTTATT 1 chr2:235741461-235741961 ( 30) TATTATTATTGTTATT 1 chr1_KI270713v1_random:2 ( 60) TATTATTATTGTTATT 1 chr19:35881936-35882436 ( 19) TATTTTTATTTTTATT 1 chr12:112942521-11294302 ( 78) TATTATTATTGTTATT 1 chr12:1085293-1085793 ( 52) TATTATTATTATTGTT 1 chr6:144482120-144482620 ( 75) TATTATTATTATTGTT 1 chr21:31582137-31582637 ( 14) TATTATTATTATTGTT 1 chr16:24970657-24971157 ( 12) TATTATTATTTTTGTT 1 chr3:187744894-187745394 ( 24) TATTATTATTATTGTT 1 chr19:40556267-40556767 ( 44) TATTGTTATTTTTATT 1 chr14:54818832-54819332 ( 76) TATTGTTATTATTATT 1 chr19:3047348-3047848 ( 15) TATTGTTATTATTATT 1 chr15:73738476-73738976 ( 13) TATTTTTATTTTTTTT 1 chr1:226790505-226791005 ( 85) TATTGTTATTATTATT 1 chr19:16292326-16292826 ( 83) TGTTATTATTATTATT 1 chr12:117189352-11718985 ( 49) TATTATTATTGTTGTT 1 chr19:40508804-40509304 ( 57) TATTATTATTGTTGTT 1 chr20:1469724-1470224 ( 2) TGTTGTTATTATTATT 1 chr1:26329828-26330328 ( 84) TATTATTGTTGTTATT 1 chr1:11297705-11298205 ( 37) TACTATTATTGTTTTT 1 chr17:43574902-43575402 ( 14) TATTATTATTATTGCT 1 chr5:174327120-174327620 ( 57) TGTTATTACTATTATT 1 chr17:7616403-7616903 ( 35) TATTATTATTATTTGT 1 chr1:50978972-50979472 ( 27) TGTTTTTGTTTTTATT 1 chr19:58278888-58279388 ( 62) TATTGTTGTTATTGTT 1 chr16:30408586-30409086 ( 24) TATTATTACTGTTGTT 1 chr1:28648566-28649066 ( 49) TGTTTTTTTTTTTTTT 1 chr19:41376159-41376659 ( 77) TGCTGTTATTATTATT 1 chr12:120533965-12053446 ( 47) TTTTGTTTTTTTTATT 1 chr6:27214821-27215321 ( 64) TGTTTTTGTTTTTGTT 1 chr13:46551297-46551797 ( 56) TATTATTATTGTCGTT 1 chr17:75368277-75368777 ( 48) TGTTTTTTTTTTTGTT 1 chr5:150459727-150460227 ( 75) TATTATTATCGTTGTT 1 chr6:2634300-2634800 ( 41) TGTTATTATTATCTTT 1 chr19:40719213-40719713 ( 79) TACTTTTTTTTTTTTT 1 chr21:36122987-36123487 ( 39) TTTTTTTATTATTTAT 1 chr12:8949986-8950486 ( 69) AATTATTATTGTTACT 1 chr6:44247016-44247516 ( 29) TGTTGTTTTTGTTTTT 1 chr22:32472788-32473288 ( 81) TGTTGTTGTTGTTGTT 1 chr16:3183985-3184485 ( 38) TGTTGTTGTTGTTGTT 1 chr19:38962006-38962506 ( 3) AATTATTATTTATTTT 1 chr12:54051953-54052453 ( 7) TAATGTGATTTTTTTT 1 chr6:135030492-135030992 ( 58) TATTGTTATTTTTCCT 1 chr15:71780260-71780760 ( 59) TGTTTTTGTTTGTTTT 1 chr1:233293988-233294488 ( 79) TACTATTACTTTTTCT 1 chr1:151012476-151012976 ( 83) TATTATTCTCATTTTT 1 chr5:160008628-160009128 ( 25) TATTTATTTATTTATT 1 chr19:40567067-40567567 ( 33) TATTTATTTATTTATT 1 chr6:42565310-42565810 ( 45) TGTTGTTGTTTGTTTT 1 chr7:114085831-114086331 ( 12) TGTTATTGTCGTTGTT 1 chr14:32134462-32134962 ( 54) TGATGATATTTTTATT 1 chr1:232670018-232670518 ( 47) AGTTGTTACTGTTATT 1 chr19:44259443-44259943 ( 23) TTTTTGTATTTTTAGT 1 chr19:39033051-39033551 ( 57) TTTTTGTATTTTTAGT 1 chr1:236089906-236090406 ( 85) TTTTTGTATTTTTAGT 1 chr19:38243750-38244250 ( 11) TTTTATTTTATTTTAT 1 chr1:155193878-155194378 ( 64) AATTTTTGTAGTTTTT 1 chr12:47080555-47081055 ( 3) TTTTTTTCTTTTTTCT 1 chr1:146035622-146036122 ( 51) TTTCTTTATTTGTGTT 1 chr19:1442273-1442773 ( 48) TACTTTTGCATTTTTT 1 chr1:67850428-67850928 ( 83) AGCTCTTATTATTATT 1 chr19:44212611-44213111 ( 11) TATCTTTATTGCTATT 1 chr19:36528785-36529285 ( 45) TGTTAGGACTGTTATT 1 chr1:30488250-30488750 ( 6) TACTATTACCATTACT 1 chr19:48645976-48646476 ( 59) ATTTAATTTTGTTGTT 1 chrUn_KI270467v1:2907-34 ( 29) TACTTTGATATTTTAT 1 chrUn_KI270466v1:187-687 ( 55) TACTTTGATATTTTAT 1 chrUn_KI270467v1:2070-25 ( 33) TACTTTGATATTTTAT 1 chrUn_KI270467v1:3122-36 ( 65) TACTTTGATATTTTAT 1 chr12:70242753-70243253 ( 38) TGTTTGTGTTTGTGTT 1 chr19:34218154-34218654 ( 84) TTTTGTGGTTTGTTTT 1 chr11:62841286-62841786 ( 52) TTATGTTCTTGTTGTT 1 chr1:51519416-51519916 ( 50) CATTATTATTTTCTAT 1 chr5:149449008-149449508 ( 3) TGACATTATTAATATT 1 chr10:45564504-45565004 ( 49) TGTTATTGTCGTCGTT 1 chr17:8226686-8227186 ( 79) TTTTTTTGTGTGTGTT 1 chr19:35535955-35536455 ( 52) TAATAGTACTTTTCTT 1 chr17:8173083-8173583 ( 46) TGCTATTGCTGTTTGT 1 chr1:61692230-61692730 ( 55) TTCTTTTTCTTTCTTT 1 chr5:112160615-112161115 ( 73) TGCTGTGGTTTTTGCT 1 chr5:38783078-38783578 ( 4) TATTGTTGCTGGTGCT 1 chr17:58631420-58631920 ( 6) TTCTGGGTTTTTTTTT 1 chr5:148825829-148826329 ( 1) TTCTGTGTTTGTTTCT 1 chr3:4987101-4987601 ( 49) TATCATTATGGGTACT 1 chr1:146387203-146387703 ( 61) AGATATTATGGTTACT 1 chr17:7484227-7484727 ( 42) TACTTATTTATTCGTT 1 chr1:148402448-148402948 ( 56) AGCTTATACTTATATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 9.43842 E= 2.2e-317 -153 -501 -1344 214 160 -1344 -32 -62 -195 -85 -1344 191 -1344 -302 -1344 221 137 -501 -56 28 -195 -1344 -221 208 -1344 -1344 -169 213 173 -343 -85 -83 -1344 -143 -1344 210 -121 -269 -343 201 89 -1344 -21 79 -295 -501 -202 210 -1344 -243 -1344 218 122 -401 -32 33 -172 -156 -269 193 -1344 -1344 -1344 226 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 111 E= 2.2e-317 0.072072 0.009009 0.000000 0.918919 0.630631 0.000000 0.234234 0.135135 0.054054 0.162162 0.000000 0.783784 0.000000 0.036036 0.000000 0.963964 0.540541 0.009009 0.198198 0.252252 0.054054 0.000000 0.063063 0.882883 0.000000 0.000000 0.090090 0.909910 0.693694 0.027027 0.162162 0.117117 0.000000 0.108108 0.000000 0.891892 0.090090 0.045045 0.027027 0.837838 0.387387 0.000000 0.252252 0.360360 0.027027 0.009009 0.072072 0.891892 0.000000 0.054054 0.000000 0.945946 0.486486 0.018018 0.234234 0.261261 0.063063 0.099099 0.045045 0.792793 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TATTATTATTDTTWTT MEME-1 regular expression -------------------------------------------------------------------------------- T[AG]TT[AT]TTATT[ATG]TT[ATG]TT -------------------------------------------------------------------------------- Time 501.90 secs. ******************************************************************************** ******************************************************************************** MOTIF ACAMAMACAMAMACAMAMAYAM MEME-2 width = 22 sites = 76 llr = 1201 E-value = 9.5e-196 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 Description -------------------------------------------------------------------------------- Simplified A 92a465919463928464a184 pos.-specific C 16:51516:535:71425:6:6 probability G ::::::1:11:::::1::::1: matrix T :2:12::3::11:1:12::4:: bits 2.3 2.0 * * 1.8 * * * 1.6 * * * * * * Relative 1.4 * * * * * * * * Entropy 1.1 * * * * * * * * (22.8 bits) 0.9 * * ** * * * * ** 0.7 *********** *** ****** 0.5 ********************** 0.2 ********************** 0.0 ---------------------- Multilevel ACACACACACACACACACACAC consensus A ATA T ACA ATA T A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr20:52972214-52972714 - 11 3.00e-12 ACATATGCAC ACACACACAAACACACACACAC ACCCTCGCAC chr5:134556862-134557362 + 18 3.00e-12 cacacacacc acacaaacacacacacacacac agtgattact chr19:35947339-35947839 - 59 4.80e-12 ACACACACAC ACACACACACACACACACACAC GAACAGTGCC chr19:36837855-36838355 + 55 4.80e-12 GTGCGCGcac acacacacacacacacacatac acacacacac chr1:161097515-161098015 - 23 4.80e-12 ACACACACAC ACACACACACACACACACACAC AGAGAGAGAG chr19:34973379-34973879 - 27 4.80e-12 ACACACACAC ACACACACACACACACACACAC ACTTCCTCTG chr10:92592417-92592917 + 23 4.80e-12 tccgtctcTc acacacacacacacacacacac acacacaAAG chr19:33797037-33797537 - 13 4.80e-12 ACACACACAC ACACACACACACACACACACAC ACCGCGCGGC chr1:21345686-21346186 - 2 4.80e-12 ACACACACAC ACACACACACACACACACACAC A chr19:35819803-35820303 + 55 4.80e-12 aacccaatgt acacacacacacacacacacac acacacacac chr1:226711170-226711670 - 75 4.80e-12 CAAC ACACACACACACACACACACAC ACTCTCTCTC chr19:39320111-39320611 + 1 4.80e-12 . acacacacacacacacacacac acacacacaA chr10:101442020-10144252 - 74 4.80e-12 TACAC ACACACACACACACACACATAC ACACAGAGAC chr1:150235772-150236272 + 72 2.01e-11 gcacgcgcgc acacacatacacacacacatac acacaca chr19:36213947-36214447 + 1 3.61e-11 . acatacacacaaacacacacac CAAGGGATAC chr6:113856712-113857212 + 26 1.43e-10 ACTCGCATAC ACACACATACACATAAACACAC GGAAAGATGG chr19:36916386-36916886 - 59 2.62e-10 TCGTGCCGTC ACACTCACACACACAACCACAC ACCCACACTA chr1:208021748-208022248 - 78 4.59e-10 C ACACACACACACACACACACGA GATACCGTGG chr6:7250761-7251261 - 42 4.59e-10 GAAACCCCAA ATAATAATAACAACAAAAACAA CAATAACAAC chr3:14764280-14764780 - 22 7.78e-10 AACAACAACA ACAACAACAACAACAATAATAA TAATAATAAT chr17:48595521-48596021 - 46 7.78e-10 AATAATAATA ACAACAACAACAACAATAATAA AGATGTGAAA chr3:134795177-134795677 + 26 8.84e-10 cacctctccc ataaacacacacacacacatgc acacccacac chr12:120533965-12053446 + 66 8.84e-10 aacaaaacca aaacaaacaaacaaacaaaaac caaaaaacaa chr12:106075006-10607550 + 79 1.00e-09 CAGTATTAAT CAacacacacacacacacacac chr2:235741461-235741961 - 50 1.46e-09 AACAATAATA ATAATAACAACAACAACAATAA TAATAATAAC chr1:235688752-235689252 + 70 1.46e-09 aataataata ataataacaacaacaacaacaa caacaataa chr10:23411313-23411813 + 22 1.65e-09 atctcaaaTa acaacaacaacaacaacaacaa caacaataat chr3:183107272-183107772 - 66 1.65e-09 CTTCATTTCA ACAACAACAACAACAACAACAA CAAATAATAA chr8:65731762-65732262 - 28 1.65e-09 GTCTAAAATA ACAACAACAACAACAACAACAA CAATAATAAT chr1:19642506-19643006 + 46 1.65e-09 aataataaTa acaacaacaacaacaacaacaa caacttcatt chr1:44487450-44487950 + 48 3.00e-09 aataataata ataataataataacaataataa taatacaaaa chr2:61136737-61137237 + 32 3.00e-09 gactgtctcc aaaaCaacaacaacaacaacaa cgataataat chr5:160008628-160009128 + 44 3.79e-09 ataaataaat aaataaataaataaataaataa ataaataaat chr19:35881936-35882436 + 41 3.79e-09 aataaaaaat aaataaataaataaataaataa ataaataaat chr19:40567067-40567567 + 52 3.79e-09 ataaataaat aaataaataaataaataaataa ataaaGTCTT chr21:36122987-36123487 + 9 3.79e-09 aaaaaaat aaataaataaataaataaataa ataaataaat chr19:16292326-16292826 - 59 3.79e-09 TAATAACAAC AAATAAATAAATAAATAAATAA AATGGCCAGC chr1_KI270713v1_random:2 - 77 4.25e-09 AC ACATACACACGCACAATAATAA TAATAACAAT chr1:154607548-154608048 + 55 4.25e-09 TGGCAAGACG ACACACACCCACACACACACAC TCACAAGACG chr12:112942521-11294302 - 47 4.76e-09 AGAAACAACA ACAATAATAGAAATAATAATAA TAGTAAACAC chr16:85522948-85523448 - 13 6.64e-09 CAGGGCAGAC ACAACCACAGCCACATACACAC AACACACACA chr5:149755386-149755886 - 30 1.40e-08 AATAATAATA ATAATAATAATAATAATAATAA CAATAATAAT chr19:13727312-13727812 + 61 1.40e-08 aataataata ataataataataataataataa ATAAAAGACA chr19:40508804-40509304 - 75 2.11e-08 AAAA AAAAAAAAAAAAAAAGCAATAA ACAACAACAA chr19:37371123-37371623 - 70 3.45e-08 CACGCGCAC AAACACACACACACAGTGACAC AAGATCACAT chr17:18363685-18364185 - 74 4.17e-08 GTCTC AAAAAAATAAAAATAAAAAATA ACAAAAATAA chr8:28401381-28401881 - 34 7.98e-08 CGCACACACG ACACACATACGTACACACATGC GTGCACACAC chr1:226308702-226309202 + 17 9.55e-08 CCCCAGAAAC CAACACACAGACACCATAACAA AGGCGGCGAC chr19:43682205-43682705 + 40 1.48e-07 aataataata ataataataataataataatga aaagaaaaag chr6:89281842-89282342 + 70 1.48e-07 acgtgcacac acattcgcacatatatacacac tctctcaca chr3:9249072-9249572 + 13 1.61e-07 GCGcactcac acacacatgcacacgtacacac actcacgcat chr7:99616303-99616803 + 8 1.76e-07 tgacTac acatacacacacgcacgcacac TACCCGGGGT chr2:43219433-43219933 + 9 1.91e-07 acacaaca cacacaacacacacacacacac TCTTTCAAGG chr6:135030492-135030992 + 34 2.90e-07 AGGAAAAGTA ACAATAAAGAAGAAAATAATAA AGAGGAAAAA chr19:36572894-36573394 + 2 3.71e-07 C TCACACACACACACCACAATGA CGTCGTAAAC chr19:47229841-47230341 + 6 4.02e-07 AACAC ACACACACTACAACCTCCACAC CCCAGCACAC chr3:69250106-69250606 - 1 4.35e-07 ACCACAGCTA TTTAAAATAGACACACACACAC chr19:44164465-44164965 + 61 4.71e-07 ggtgggggcc ataaacactcagaccataataA TACCTAAAGA chr1:11297705-11298205 - 54 5.96e-07 AAAACTTCGT CTCAAAAAAAAAACAAAAAAAC AAAAAACAAT chr1:50978972-50979472 + 45 9.40e-07 caaaaacaaa aaacaaccagccaaaaacaTCA GCTCTTTGGG chr1:40691643-40692143 - 25 1.01e-06 CCTCGCACAG AAACTCCCGCACACTCACACAC CTCTGCTCAG chr21:37366796-37367296 - 71 1.09e-06 GCTCCCTC GCACACACACTCGCACTCACAC CGGTCCCGCC chr6:26571549-26572049 - 21 1.09e-06 TCTTGCTGAC ACATAAGCAGCTAACAACACAC TCCCGTATCA chr20:1469724-1470224 + 72 1.09e-06 ACAACATCTT CAACTAATGACAATAATAATAA AATAACA chr19:36215210-36215710 - 8 1.17e-06 CCTCTTAGGC ACAATCACACACAATCCCGCAC CCAGTTT chr19:38224231-38224731 + 66 1.36e-06 attcacgcgg atactcacagcctcccacacac tcctactcac chr22:29602720-29603220 + 62 1.36e-06 aataataata acaataataataataatTCTAA AGGGAAGCAG chr11:62841286-62841786 + 29 1.46e-06 CACACTAGCG ATAAAAACACCTAATCCAACTC AAACAACAAG chr7:66920710-66921210 + 74 1.46e-06 tacacgatgc acactacaagccacatacacgc actac chr5:174327120-174327620 - 77 1.94e-06 TA ATAATAAAAACAACAGTTATGA TGACAATAAT chr19:43901264-43901764 + 50 2.94e-06 TTCATTTGTC TAACGCACACACACGTACACAA CCCTGTTCAT chr8:21788557-21789057 - 29 2.94e-06 AGAGAGAAAG ACACACGCACGCAGAGACACAC GGTCACTGGA chr6:42565310-42565810 - 19 3.60e-06 ACAACAAAAC ACACCCAAACAAGCAAAGATTC AGCATTTAAC chr1:232670018-232670518 + 18 3.85e-06 CGCTTAAAAG CAATCAAAAAAGAACAAAATAC CATCATCAAT chr19:36488967-36489467 + 17 5.01e-06 CACTACGGGG ACAAACGCAGTAACACTCAACC AGGCACAAGC chr19:39411901-39412401 - 6 6.91e-06 TACACATCTA ATAAACCAACCAAAACATCTAC ATCAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:52972214-52972714 3e-12 10_[-2]_68 chr5:134556862-134557362 3e-12 17_[+2]_61 chr19:35947339-35947839 4.8e-12 58_[-2]_20 chr19:36837855-36838355 4.8e-12 54_[+2]_24 chr1:161097515-161098015 4.8e-12 22_[-2]_56 chr19:34973379-34973879 4.8e-12 26_[-2]_52 chr10:92592417-92592917 4.8e-12 22_[+2]_56 chr19:33797037-33797537 4.8e-12 12_[-2]_66 chr1:21345686-21346186 4.8e-12 1_[-2]_77 chr19:35819803-35820303 4.8e-12 54_[+2]_24 chr1:226711170-226711670 4.8e-12 74_[-2]_4 chr19:39320111-39320611 4.8e-12 [+2]_78 chr10:101442020-10144252 4.8e-12 73_[-2]_5 chr1:150235772-150236272 2e-11 71_[+2]_7 chr19:36213947-36214447 3.6e-11 [+2]_78 chr6:113856712-113857212 1.4e-10 25_[+2]_53 chr19:36916386-36916886 2.6e-10 58_[-2]_20 chr1:208021748-208022248 4.6e-10 77_[-2]_1 chr6:7250761-7251261 4.6e-10 41_[-2]_37 chr3:14764280-14764780 7.8e-10 21_[-2]_57 chr17:48595521-48596021 7.8e-10 45_[-2]_33 chr3:134795177-134795677 8.8e-10 25_[+2]_53 chr12:120533965-12053446 8.8e-10 65_[+2]_13 chr12:106075006-10607550 1e-09 78_[+2] chr2:235741461-235741961 1.5e-09 49_[-2]_29 chr1:235688752-235689252 1.5e-09 69_[+2]_9 chr10:23411313-23411813 1.7e-09 21_[+2]_57 chr3:183107272-183107772 1.7e-09 65_[-2]_13 chr8:65731762-65732262 1.7e-09 27_[-2]_51 chr1:19642506-19643006 1.7e-09 45_[+2]_33 chr1:44487450-44487950 3e-09 47_[+2]_31 chr2:61136737-61137237 3e-09 31_[+2]_47 chr5:160008628-160009128 3.8e-09 43_[+2]_35 chr19:35881936-35882436 3.8e-09 40_[+2]_38 chr19:40567067-40567567 3.8e-09 51_[+2]_27 chr21:36122987-36123487 3.8e-09 8_[+2]_70 chr19:16292326-16292826 3.8e-09 58_[-2]_20 chr1_KI270713v1_random:2 4.2e-09 76_[-2]_2 chr1:154607548-154608048 4.2e-09 54_[+2]_24 chr12:112942521-11294302 4.8e-09 46_[-2]_32 chr16:85522948-85523448 6.6e-09 12_[-2]_66 chr5:149755386-149755886 1.4e-08 29_[-2]_49 chr19:13727312-13727812 1.4e-08 60_[+2]_18 chr19:40508804-40509304 2.1e-08 74_[-2]_4 chr19:37371123-37371623 3.4e-08 69_[-2]_9 chr17:18363685-18364185 4.2e-08 73_[-2]_5 chr8:28401381-28401881 8e-08 33_[-2]_45 chr1:226308702-226309202 9.5e-08 16_[+2]_62 chr19:43682205-43682705 1.5e-07 39_[+2]_39 chr6:89281842-89282342 1.5e-07 69_[+2]_9 chr3:9249072-9249572 1.6e-07 12_[+2]_66 chr7:99616303-99616803 1.8e-07 7_[+2]_71 chr2:43219433-43219933 1.9e-07 8_[+2]_70 chr6:135030492-135030992 2.9e-07 33_[+2]_45 chr19:36572894-36573394 3.7e-07 1_[+2]_77 chr19:47229841-47230341 4e-07 5_[+2]_73 chr3:69250106-69250606 4.4e-07 [-2]_78 chr19:44164465-44164965 4.7e-07 60_[+2]_18 chr1:11297705-11298205 6e-07 53_[-2]_25 chr1:50978972-50979472 9.4e-07 44_[+2]_34 chr1:40691643-40692143 1e-06 24_[-2]_54 chr21:37366796-37367296 1.1e-06 70_[-2]_8 chr6:26571549-26572049 1.1e-06 20_[-2]_58 chr20:1469724-1470224 1.1e-06 71_[+2]_7 chr19:36215210-36215710 1.2e-06 7_[-2]_71 chr19:38224231-38224731 1.4e-06 65_[+2]_13 chr22:29602720-29603220 1.4e-06 61_[+2]_17 chr11:62841286-62841786 1.5e-06 28_[+2]_50 chr7:66920710-66921210 1.5e-06 73_[+2]_5 chr5:174327120-174327620 1.9e-06 76_[-2]_2 chr19:43901264-43901764 2.9e-06 49_[+2]_29 chr8:21788557-21789057 2.9e-06 28_[-2]_50 chr6:42565310-42565810 3.6e-06 18_[-2]_60 chr1:232670018-232670518 3.9e-06 17_[+2]_61 chr19:36488967-36489467 5e-06 16_[+2]_62 chr19:39411901-39412401 6.9e-06 5_[-2]_73 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACAMAMACAMAMACAMAMAYAM width=22 seqs=76 chr20:52972214-52972714 ( 11) ACACACACAAACACACACACAC 1 chr5:134556862-134557362 ( 18) ACACAAACACACACACACACAC 1 chr19:35947339-35947839 ( 59) ACACACACACACACACACACAC 1 chr19:36837855-36838355 ( 55) ACACACACACACACACACATAC 1 chr1:161097515-161098015 ( 23) ACACACACACACACACACACAC 1 chr19:34973379-34973879 ( 27) ACACACACACACACACACACAC 1 chr10:92592417-92592917 ( 23) ACACACACACACACACACACAC 1 chr19:33797037-33797537 ( 13) ACACACACACACACACACACAC 1 chr1:21345686-21346186 ( 2) ACACACACACACACACACACAC 1 chr19:35819803-35820303 ( 55) ACACACACACACACACACACAC 1 chr1:226711170-226711670 ( 75) ACACACACACACACACACACAC 1 chr19:39320111-39320611 ( 1) ACACACACACACACACACACAC 1 chr10:101442020-10144252 ( 74) ACACACACACACACACACATAC 1 chr1:150235772-150236272 ( 72) ACACACATACACACACACATAC 1 chr19:36213947-36214447 ( 1) ACATACACACAAACACACACAC 1 chr6:113856712-113857212 ( 26) ACACACATACACATAAACACAC 1 chr19:36916386-36916886 ( 59) ACACTCACACACACAACCACAC 1 chr1:208021748-208022248 ( 78) ACACACACACACACACACACGA 1 chr6:7250761-7251261 ( 42) ATAATAATAACAACAAAAACAA 1 chr3:14764280-14764780 ( 22) ACAACAACAACAACAATAATAA 1 chr17:48595521-48596021 ( 46) ACAACAACAACAACAATAATAA 1 chr3:134795177-134795677 ( 26) ATAAACACACACACACACATGC 1 chr12:120533965-12053446 ( 66) AAACAAACAAACAAACAAAAAC 1 chr12:106075006-10607550 ( 79) CAACACACACACACACACACAC 1 chr2:235741461-235741961 ( 50) ATAATAACAACAACAACAATAA 1 chr1:235688752-235689252 ( 70) ATAATAACAACAACAACAACAA 1 chr10:23411313-23411813 ( 22) ACAACAACAACAACAACAACAA 1 chr3:183107272-183107772 ( 66) ACAACAACAACAACAACAACAA 1 chr8:65731762-65732262 ( 28) ACAACAACAACAACAACAACAA 1 chr1:19642506-19643006 ( 46) ACAACAACAACAACAACAACAA 1 chr1:44487450-44487950 ( 48) ATAATAATAATAACAATAATAA 1 chr2:61136737-61137237 ( 32) AAAACAACAACAACAACAACAA 1 chr5:160008628-160009128 ( 44) AAATAAATAAATAAATAAATAA 1 chr19:35881936-35882436 ( 41) AAATAAATAAATAAATAAATAA 1 chr19:40567067-40567567 ( 52) AAATAAATAAATAAATAAATAA 1 chr21:36122987-36123487 ( 9) AAATAAATAAATAAATAAATAA 1 chr19:16292326-16292826 ( 59) AAATAAATAAATAAATAAATAA 1 chr1_KI270713v1_random:2 ( 77) ACATACACACGCACAATAATAA 1 chr1:154607548-154608048 ( 55) ACACACACCCACACACACACAC 1 chr12:112942521-11294302 ( 47) ACAATAATAGAAATAATAATAA 1 chr16:85522948-85523448 ( 13) ACAACCACAGCCACATACACAC 1 chr5:149755386-149755886 ( 30) ATAATAATAATAATAATAATAA 1 chr19:13727312-13727812 ( 61) ATAATAATAATAATAATAATAA 1 chr19:40508804-40509304 ( 75) AAAAAAAAAAAAAAAGCAATAA 1 chr19:37371123-37371623 ( 70) AAACACACACACACAGTGACAC 1 chr17:18363685-18364185 ( 74) AAAAAAATAAAAATAAAAAATA 1 chr8:28401381-28401881 ( 34) ACACACATACGTACACACATGC 1 chr1:226308702-226309202 ( 17) CAACACACAGACACCATAACAA 1 chr19:43682205-43682705 ( 40) ATAATAATAATAATAATAATGA 1 chr6:89281842-89282342 ( 70) ACATTCGCACATATATACACAC 1 chr3:9249072-9249572 ( 13) ACACACATGCACACGTACACAC 1 chr7:99616303-99616803 ( 8) ACATACACACACGCACGCACAC 1 chr2:43219433-43219933 ( 9) CACACAACACACACACACACAC 1 chr6:135030492-135030992 ( 34) ACAATAAAGAAGAAAATAATAA 1 chr19:36572894-36573394 ( 2) TCACACACACACACCACAATGA 1 chr19:47229841-47230341 ( 6) ACACACACTACAACCTCCACAC 1 chr3:69250106-69250606 ( 1) TTTAAAATAGACACACACACAC 1 chr19:44164465-44164965 ( 61) ATAAACACTCAGACCATAATAA 1 chr1:11297705-11298205 ( 54) CTCAAAAAAAAAACAAAAAAAC 1 chr1:50978972-50979472 ( 45) AAACAACCAGCCAAAAACATCA 1 chr1:40691643-40692143 ( 25) AAACTCCCGCACACTCACACAC 1 chr21:37366796-37367296 ( 71) GCACACACACTCGCACTCACAC 1 chr6:26571549-26572049 ( 21) ACATAAGCAGCTAACAACACAC 1 chr20:1469724-1470224 ( 72) CAACTAATGACAATAATAATAA 1 chr19:36215210-36215710 ( 8) ACAATCACACACAATCCCGCAC 1 chr19:38224231-38224731 ( 66) ATACTCACAGCCTCCCACACAC 1 chr22:29602720-29603220 ( 62) ACAATAATAATAATAATTCTAA 1 chr11:62841286-62841786 ( 29) ATAAAAACACCTAATCCAACTC 1 chr7:66920710-66921210 ( 74) ACACTACAAGCCACATACACGC 1 chr5:174327120-174327620 ( 77) ATAATAAAAACAACAGTTATGA 1 chr19:43901264-43901764 ( 50) TAACGCACACACACGTACACAA 1 chr8:21788557-21789057 ( 29) ACACACGCACGCAGAGACACAC 1 chr6:42565310-42565810 ( 19) ACACCCAAACAAGCAAAGATTC 1 chr1:232670018-232670518 ( 18) CAATCAAAAAAGAACAAAATAC 1 chr19:36488967-36489467 ( 17) ACAAACGCAGTAACACTCAACC 1 chr19:39411901-39412401 ( 6) ATAAACCAACCAAAACATCTAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 11.099 E= 9.5e-196 206 -188 -447 -240 18 96 -1289 -8 220 -347 -1289 -398 92 66 -1289 -53 154 -101 -447 18 118 85 -1289 -1289 210 -247 -247 -1289 -99 114 -1289 26 212 -447 -247 -298 92 74 -130 -1289 154 -15 -288 -118 72 78 -288 -82 218 -1289 -288 -398 -18 123 -447 -82 201 -166 -347 -240 92 48 -247 -53 151 -77 -447 10 101 82 -347 -240 220 -347 -447 -1289 -198 92 -1289 92 201 -347 -166 -240 106 96 -1289 -1289 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 76 E= 9.5e-196 0.868421 0.078947 0.013158 0.039474 0.236842 0.565789 0.000000 0.197368 0.960526 0.026316 0.000000 0.013158 0.394737 0.460526 0.000000 0.144737 0.605263 0.144737 0.013158 0.236842 0.473684 0.526316 0.000000 0.000000 0.894737 0.052632 0.052632 0.000000 0.105263 0.644737 0.000000 0.250000 0.907895 0.013158 0.052632 0.026316 0.394737 0.486842 0.118421 0.000000 0.605263 0.263158 0.039474 0.092105 0.342105 0.500000 0.039474 0.118421 0.947368 0.000000 0.039474 0.013158 0.184211 0.684211 0.013158 0.118421 0.842105 0.092105 0.026316 0.039474 0.394737 0.407895 0.052632 0.144737 0.592105 0.171053 0.013158 0.223684 0.421053 0.513158 0.026316 0.039474 0.960526 0.026316 0.013158 0.000000 0.052632 0.552632 0.000000 0.394737 0.842105 0.026316 0.092105 0.039474 0.434211 0.565789 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAMAMACAMAMACAMAMAYAM MEME-2 regular expression -------------------------------------------------------------------------------- A[CA]A[CA][AT][CA]A[CT]A[CA][AC][CA]ACA[CA][AT][CA]A[CT]A[CA] -------------------------------------------------------------------------------- Time 933.25 secs. ******************************************************************************** ******************************************************************************** MOTIF TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 width = 38 sites = 16 llr = 644 E-value = 1.9e-140 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::::9:11a:::1919:12:31:a::::9:::19:::: pos.-specific C 1::a1::1::981:1::6:8:9a:8::a:8:99:199: probability G 119:1a18:9:19:9:128:71::::a:1::::191:1 matrix T 991:::9::111:1:191121:::2a:::2a1::::19 bits 2.3 * * * * 2.0 * * * * * 1.8 * * * * * ** ** **** * * * 1.6 ******* *** * ** ** **** **** ** Relative 1.4 ******* *** * ** ** **** **** *** Entropy 1.1 ******* *** ***** * ***************** (58.1 bits) 0.9 ***************** ******************** 0.7 ***************** ******************** 0.5 ************************************** 0.2 ************************************** 0.0 -------------------------------------- Multilevel TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- -------------------------------------- chr5:181218520-181219020 + 43 4.19e-23 catgcggagc ttgcagtgagccgagatcgcgccactgcactccagcct gggcgacaca chr22:32472788-32473288 + 17 1.02e-22 gaggcggagc ttgcagtgagccgagatcacgccactgcactccagcct gggcgacaga chr21:39384081-39384581 - 19 5.84e-22 GAGGCAGAGG TTGCAGTGAGCCGAGATAGCGCCACTGCACTCCAGCCT CGGCAAAAGA chr11:59557580-59558080 + 63 1.05e-21 gaggcggagg ttgcagtgagccgagatggcgccattgcactccagcct chr6:27231225-27231725 + 61 1.05e-21 gaggcggagg ttgcagtgagccgagatcgtgccactgcattccagcct ga chr1:226790505-226791005 + 20 1.30e-21 gaggtagagg ttgcagtgagccgagattgtgccactgcactccagcct gggtgacaga chr9:129824300-129824800 + 35 1.86e-21 gaggcggaga ttgcagtgagccgagatctcaccactgcactccagcct gggagacaga chr12:120201292-12020179 - 32 1.04e-19 GAGGCGGAGC TTGCAGTCAGCCGAGATGGCGCCACTGCGCTCCAGCCT GGGCGACAGA chr19:34478445-34478945 - 50 1.49e-19 GAGGCAGAGG TTGCAGTGAGCCAAGATGACACCACTGCATTCCAGCCT GGGTGACACA chr22:39399223-39399723 + 55 1.68e-19 aaggcagagg ttgcagggagctgtgatcgcgccactgcactccagcct gggtgaca chr8:43093769-43094269 + 46 3.02e-19 ggggcggagg tttcagtgagccgaaatcgcgccactgcacttcagcct gggggccaga chr19:38954718-38955218 - 56 3.84e-19 GCGGAGC TTGCAGTGAGCCGACATCGCACCACTGCATTCCAGGCT GGGCAACAGA chr16:40589-41089 + 9 5.34e-19 ggcagagg ttgcagtgagccgagatcatgacattgcactccaccct gggcaacaag chr20:37177999-37178499 + 48 2.66e-18 gatgtcgagg ctgcagtaagctgtgatcgcaccactgcactccagcct gggcgacaga chr6:28790339-28790839 + 48 9.47e-15 gaggcggagg ttgcggtgagccgagttcgctccattgcactcagcctg ggcaacaaga chr10:13298621-13299121 + 37 6.76e-13 aggttgcagt gggccgacattgcagagtgcggcactgcactccagcct gaccacagag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:181218520-181219020 4.2e-23 42_[+3]_20 chr22:32472788-32473288 1e-22 16_[+3]_46 chr21:39384081-39384581 5.8e-22 18_[-3]_44 chr11:59557580-59558080 1.1e-21 62_[+3] chr6:27231225-27231725 1.1e-21 60_[+3]_2 chr1:226790505-226791005 1.3e-21 19_[+3]_43 chr9:129824300-129824800 1.9e-21 34_[+3]_28 chr12:120201292-12020179 1e-19 31_[-3]_31 chr19:34478445-34478945 1.5e-19 49_[-3]_13 chr22:39399223-39399723 1.7e-19 54_[+3]_8 chr8:43093769-43094269 3e-19 45_[+3]_17 chr19:38954718-38955218 3.8e-19 55_[-3]_7 chr16:40589-41089 5.3e-19 8_[+3]_54 chr20:37177999-37178499 2.7e-18 47_[+3]_15 chr6:28790339-28790839 9.5e-15 47_[+3]_15 chr10:13298621-13299121 6.8e-13 36_[+3]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT width=38 seqs=16 chr5:181218520-181219020 ( 43) TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT 1 chr22:32472788-32473288 ( 17) TTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCT 1 chr21:39384081-39384581 ( 19) TTGCAGTGAGCCGAGATAGCGCCACTGCACTCCAGCCT 1 chr11:59557580-59558080 ( 63) TTGCAGTGAGCCGAGATGGCGCCATTGCACTCCAGCCT 1 chr6:27231225-27231725 ( 61) TTGCAGTGAGCCGAGATCGTGCCACTGCATTCCAGCCT 1 chr1:226790505-226791005 ( 20) TTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCT 1 chr9:129824300-129824800 ( 35) TTGCAGTGAGCCGAGATCTCACCACTGCACTCCAGCCT 1 chr12:120201292-12020179 ( 32) TTGCAGTCAGCCGAGATGGCGCCACTGCGCTCCAGCCT 1 chr19:34478445-34478945 ( 50) TTGCAGTGAGCCAAGATGACACCACTGCATTCCAGCCT 1 chr22:39399223-39399723 ( 55) TTGCAGGGAGCTGTGATCGCGCCACTGCACTCCAGCCT 1 chr8:43093769-43094269 ( 46) TTTCAGTGAGCCGAAATCGCGCCACTGCACTTCAGCCT 1 chr19:38954718-38955218 ( 56) TTGCAGTGAGCCGACATCGCACCACTGCATTCCAGGCT 1 chr16:40589-41089 ( 9) TTGCAGTGAGCCGAGATCATGACATTGCACTCCACCCT 1 chr20:37177999-37178499 ( 48) CTGCAGTAAGCTGTGATCGCACCACTGCACTCCAGCCT 1 chr6:28790339-28790839 ( 48) TTGCGGTGAGCCGAGTTCGCTCCATTGCACTCAGCCTG 1 chr10:13298621-13299121 ( 37) GGGCCGACATTGCAGAGTGCGGCACTGCACTCCAGCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 38 n= 37800 bayes= 11.2055 E= 1.9e-140 -1064 -222 -222 207 -1064 -1064 -222 217 -1064 -1064 168 -174 -1064 178 -1064 -1064 207 -222 -222 -1064 -1064 -1064 178 -1064 -174 -1064 -222 207 -174 -122 148 -1064 226 -1064 -1064 -1064 -1064 -1064 168 -174 -1064 168 -1064 -174 -1064 148 -222 -74 -174 -222 158 -1064 207 -1064 -1064 -74 -174 -222 158 -1064 217 -1064 -1064 -174 -1064 -1064 -222 217 -174 110 -64 -74 -15 -1064 136 -174 -1064 148 -1064 -15 26 -1064 124 -174 -174 158 -222 -1064 -1064 178 -1064 -1064 226 -1064 -1064 -1064 -1064 148 -1064 -15 -1064 -1064 -1064 226 -1064 -1064 178 -1064 -1064 178 -1064 -1064 217 -1064 -222 -1064 -1064 148 -1064 -15 -1064 -1064 -1064 226 -1064 168 -1064 -174 -174 168 -1064 -1064 217 -1064 -222 -1064 -1064 -122 158 -1064 -1064 168 -222 -1064 -1064 168 -1064 -174 -1064 -1064 -222 217 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 38 nsites= 16 E= 1.9e-140 0.000000 0.062500 0.062500 0.875000 0.000000 0.000000 0.062500 0.937500 0.000000 0.000000 0.937500 0.062500 0.000000 1.000000 0.000000 0.000000 0.875000 0.062500 0.062500 0.000000 0.000000 0.000000 1.000000 0.000000 0.062500 0.000000 0.062500 0.875000 0.062500 0.125000 0.812500 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.937500 0.062500 0.000000 0.937500 0.000000 0.062500 0.000000 0.812500 0.062500 0.125000 0.062500 0.062500 0.875000 0.000000 0.875000 0.000000 0.000000 0.125000 0.062500 0.062500 0.875000 0.000000 0.937500 0.000000 0.000000 0.062500 0.000000 0.000000 0.062500 0.937500 0.062500 0.625000 0.187500 0.125000 0.187500 0.000000 0.750000 0.062500 0.000000 0.812500 0.000000 0.187500 0.250000 0.000000 0.687500 0.062500 0.062500 0.875000 0.062500 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.812500 0.000000 0.187500 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.937500 0.000000 0.062500 0.000000 0.000000 0.812500 0.000000 0.187500 0.000000 0.000000 0.000000 1.000000 0.000000 0.937500 0.000000 0.062500 0.062500 0.937500 0.000000 0.000000 0.937500 0.000000 0.062500 0.000000 0.000000 0.125000 0.875000 0.000000 0.000000 0.937500 0.062500 0.000000 0.000000 0.937500 0.000000 0.062500 0.000000 0.000000 0.062500 0.937500 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCT MEME-3 regular expression -------------------------------------------------------------------------------- TTGCAGTGAGCCGAGATCGC[GA]CCACTGCACTCCAGCCT -------------------------------------------------------------------------------- Time 1287.41 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:4253961-4254461 3.44e-01 100 chr19:10332927-10333427 9.73e-01 100 chr6:32971004-32971504 9.45e-03 100 chr19:34501532-34502032 9.67e-01 100 chr1:154607548-154608048 8.79e-06 15_[+2(6.67e-05)]_17_[+2(4.25e-09)]_\ 24 chr1:228140151-228140651 9.69e-01 100 chr15:72117583-72118083 9.55e-01 100 chr7:92590094-92590594 9.66e-01 100 chr19:39397576-39398076 8.08e-01 100 chr7:99616303-99616803 3.35e-04 7_[+2(1.76e-07)]_71 chr8:11802689-11803189 9.92e-01 100 chr16:40589-41089 5.37e-27 8_[+3(5.34e-19)]_29_[-1(2.45e-11)]_\ 9 chr1:36148917-36149417 9.97e-01 100 chr17:7484227-7484727 1.48e-02 41_[+1(1.35e-05)]_43 chr10:46030169-46030669 8.46e-01 100 chr1:151012476-151012976 1.53e-05 82_[+1(1.89e-07)]_2 chr16:30408586-30409086 4.22e-10 23_[+1(9.04e-09)]_61 chr5:140556998-140557498 9.45e-01 100 chr19:18571708-18572208 7.80e-01 100 chr5:74767004-74767504 1.69e-01 100 chr20:45971971-45972471 9.01e-01 100 chr8:94474627-94475127 8.08e-01 100 chr10:89701618-89702118 1.94e-01 100 chr22:23913519-23914019 8.36e-01 100 chr8:37538045-37538545 2.66e-11 51_[-1(2.45e-11)]_33 chr22:24555555-24556055 8.36e-01 100 chr8:11016165-11016665 9.47e-01 100 chr17:74203496-74203996 5.74e-02 100 chr17:32350253-32350753 3.94e-01 100 chr6:138109308-138109808 4.12e-02 12_[+2(7.02e-05)]_66 chr5:35617577-35618077 2.79e-01 100 chr8:16825922-16826422 9.51e-02 100 chr3:155854240-155854740 5.07e-01 100 chr1:26329828-26330328 1.33e-11 83_[-1(1.32e-09)]_1 chr6:28136630-28137130 8.89e-01 100 chr6:42565310-42565810 6.55e-10 18_[-2(3.60e-06)]_3_[-2(7.78e-10)]_\ 35 chr5:134411625-134412125 9.80e-01 100 chr5:177086896-177087396 9.03e-01 100 chr15:71780260-71780760 4.66e-09 53_[+2(3.00e-09)]_1_[-1(2.00e-05)]_\ 8 chr17:7932064-7932564 4.54e-01 100 chr1:233614103-233614603 5.78e-01 100 chr22:39399223-39399723 1.58e-14 54_[+3(1.68e-19)]_8 chr1:70411134-70411634 3.19e-01 100 chr6:96924660-96925160 9.43e-01 100 chr5:112976818-112977318 6.86e-01 100 chr3:49940094-49940594 7.52e-01 100 chr3:187744894-187745394 1.37e-09 23_[-1(1.25e-10)]_61 chr19:30225120-30225620 2.21e-01 100 chr2:96638171-96638671 8.81e-01 100 chr5:40798257-40798757 5.03e-01 100 chr1:160343318-160343818 5.16e-01 100 chr10:119178451-11917895 9.80e-01 100 chr16:87383811-87384311 8.27e-01 100 chr1:86774461-86774961 8.13e-02 100 chr14:24442353-24442853 9.28e-01 100 chr12:120533965-12053446 1.48e-10 53_[+2(1.40e-08)]_2_[+2(1.91e-08)]_\ 1 chr16:22296978-22297478 4.77e-01 100 chr10:47553231-47553731 6.48e-01 100 chr1:28581593-28582093 8.65e-01 100 chr14:24213061-24213561 9.69e-01 100 chr10:101442020-10144252 1.50e-09 26_[-1(4.40e-05)]_31_[-2(4.80e-12)]_\ 5 chr1:101025720-101026220 2.77e-01 100 chr11:78188238-78188738 5.22e-01 100 chr6:83192826-83193326 8.19e-01 100 chr19:58519734-58520234 1.90e-01 100 chr11:66001985-66002485 7.18e-01 100 chr12:56190153-56190653 6.51e-01 100 chr15:70892164-70892664 8.82e-01 100 chr8:123396269-123396769 4.59e-01 100 chr6:85679042-85679542 7.60e-01 100 chr1:179954681-179955181 8.98e-01 100 chr14:64986653-64987153 1.77e-01 100 chr1:145287515-145288015 2.75e-01 100 chr21:32771832-32772332 3.80e-03 [-3(7.15e-05)]_62 chr20:44475722-44476222 9.96e-01 100 chr19:42075307-42075807 1.99e-01 100 chr6:27231225-27231725 1.26e-16 60_[+3(1.05e-21)]_2 chr1:169486107-169486607 6.01e-01 100 chr19:4233322-4233822 9.42e-01 100 chr21:39183016-39183516 9.96e-01 100 chrX:72276832-72277332 5.31e-01 100 chr12:100200584-10020108 2.28e-01 100 chr6:116100793-116101293 4.74e-01 100 chr17:14308802-14309302 7.17e-01 100 chr20:48921094-48921594 5.61e-01 100 chr2:43219433-43219933 3.66e-04 8_[+2(1.91e-07)]_70 chr1:234608191-234608691 9.73e-01 100 chr5:111091969-111092469 7.99e-01 100 chr19:49118691-49119191 2.17e-01 100 chr17:63741342-63741842 9.98e-01 100 chr1:225653413-225653913 8.42e-01 100 chr17:48728653-48729153 9.78e-01 100 chr10:100286276-10028677 2.22e-01 100 chr19:46347139-46347639 8.87e-01 100 chr1:229221148-229221648 9.87e-01 100 chr19:47113369-47113869 1.75e-01 100 chr19:39412559-39413059 8.84e-01 100 chr1:19642506-19643006 5.35e-13 29_[-1(2.45e-11)]_[+2(1.65e-09)]_33 chr19:40285671-40286171 7.00e-01 100 chr15:75023447-75023947 4.74e-03 35_[+3(2.73e-05)]_27 chr1:155193878-155194378 1.33e-07 63_[-1(4.95e-07)]_21 chr16:88811991-88812491 9.64e-01 100 chr12:123365295-12336579 2.22e-01 100 chr17:63842540-63843040 4.99e-01 100 chr1:233293988-233294488 8.61e-05 78_[+1(1.89e-07)]_6 chr5:38783078-38783578 1.59e-02 3_[+1(7.32e-06)]_81 chr5:175378423-175378923 3.37e-02 21_[+2(7.02e-05)]_57 chr6:27603518-27604018 4.23e-13 75_[+1(2.45e-11)]_9 chr19:49850650-49851150 9.33e-01 100 chr10:70145603-70146103 8.61e-01 100 chr20:3820126-3820626 9.33e-01 100 chr7:139340520-139341020 2.13e-01 100 chr19:40508804-40509304 2.44e-11 56_[+1(3.36e-10)]_9_[+1(1.45e-08)]_\ 3 chr15:70097459-70097959 8.91e-01 100 chr5:134370992-134371492 1.02e-01 100 chr14:32134462-32134962 4.37e-04 53_[-1(3.53e-07)]_31 chr10:122953918-12295441 9.93e-01 100 chr1:25247056-25247556 1.37e-01 100 chr3:69250106-69250606 1.63e-04 [-2(4.35e-07)]_78 chr1:231040223-231040723 8.19e-01 100 chr17:18363685-18364185 5.08e-13 55_[+1(4.91e-11)]_6_[+1(6.34e-09)]_\ 7 chr16:30698658-30699158 5.30e-01 100 chr12:106075006-10607550 2.54e-07 21_[-1(7.45e-05)]_41_[+2(1.00e-09)] chr17:21042356-21042856 9.70e-01 100 chr6:11093728-11094228 8.82e-01 100 chr1:167455188-167455688 2.56e-01 100 chr20:1469724-1470224 6.79e-10 1_[-1(1.32e-09)]_27_[+1(4.19e-05)]_\ 16_[-1(6.34e-09)]_8 chr8:100952117-100952617 2.92e-02 100 chr10:71319314-71319814 7.23e-01 100 chr1:1959890-1960390 9.33e-01 100 chr9:129036582-129037082 6.71e-02 11_[-2(3.02e-05)]_67 chr12:69585371-69585871 8.99e-01 100 chr19:39320111-39320611 7.46e-08 [+2(4.80e-12)]_[+2(1.53e-05)]_56 chr2:223957198-223957698 3.25e-01 100 chr1:226711170-226711670 3.61e-08 72_[-2(4.80e-12)]_6 chr17:13337892-13338392 2.19e-01 100 chr19:38962006-38962506 6.76e-04 2_[-1(8.80e-08)]_82 chr19:13727312-13727812 4.20e-13 41_[-1(2.45e-11)]_2_[-1(2.45e-11)]_\ 25 chr19:35535955-35536455 2.55e-04 51_[-1(4.36e-06)]_33 chr21:32278552-32279052 8.54e-01 100 chr5:71455483-71455983 1.47e-01 100 chr13:44917671-44918171 3.70e-02 100 chr1:93179963-93180463 8.97e-01 100 chr17:8173083-8173583 2.46e-03 11_[-1(2.36e-05)]_18_[-1(5.66e-06)]_\ 39 chr7:139133473-139133973 8.76e-01 100 chr6:159761998-159762498 9.26e-01 100 chr5:115169477-115169977 9.59e-01 100 chr8:65731762-65732262 2.40e-13 4_[+1(2.45e-11)]_2_[+1(1.79e-08)]_2_\ [+1(3.98e-05)]_44 chr16:21599280-21599780 6.53e-01 100 chr17:82065770-82066270 8.69e-01 100 chr6:157323344-157323844 8.15e-01 100 chr1:244047734-244048234 9.57e-01 100 chr10:45564504-45565004 1.41e-06 33_[-1(2.51e-06)]_8_[-1(5.10e-05)]_\ 8_[+1(7.45e-07)]_3 chr19:35819803-35820303 3.86e-08 54_[+2(4.80e-12)]_[+2(4.80e-12)]_2 chr19:34218154-34218654 1.69e-05 83_[+1(2.18e-06)]_1 chr1:244969708-244970208 1.90e-02 100 chr5:149449008-149449508 1.04e-04 2_[-1(3.10e-06)]_40_[-1(6.79e-05)]_\ 10_[-1(1.19e-06)] chr14:70359489-70359989 1.83e-01 100 chr13:52194231-52194731 7.74e-01 100 chr17:7242772-7243272 5.39e-01 100 chr1:1307957-1308457 9.40e-01 100 chr19:35740934-35741434 6.35e-01 100 chr1:156456741-156457241 5.47e-01 100 chr5:139517799-139518299 8.57e-01 100 chr1:148402448-148402948 1.23e-02 55_[+1(3.08e-05)]_29 chr4:70688099-70688599 4.04e-01 100 chr21:34888146-34888646 3.86e-01 100 chr6:33299565-33300065 9.97e-01 100 chr17:63600650-63601150 2.47e-01 100 chr16:50369047-50369547 3.12e-01 100 chr19:47229841-47230341 6.08e-04 5_[+2(4.02e-07)]_73 chr19:40090474-40090974 1.95e-01 100 chr1:241848065-241848565 3.52e-01 100 chr1:39883086-39883586 6.10e-01 100 chr1:146387203-146387703 1.54e-03 60_[+1(1.13e-05)]_24 chr1:99849914-99850414 7.93e-01 100 chr5:38556669-38557169 8.74e-01 100 chr19:10194680-10195180 6.28e-01 100 chr3:11846490-11846990 8.21e-01 100 chr19:16292326-16292826 9.83e-12 58_[-2(3.79e-09)]_2_[+1(2.36e-10)]_\ 2 chr1:155244589-155245089 1.00e+00 100 chr5:103119894-103120394 4.53e-01 100 chr1:167714391-167714891 4.87e-01 100 chr17:48595521-48596021 4.60e-14 45_[-2(7.78e-10)]_[+1(2.45e-11)]_17 chr19:1442273-1442773 1.29e-04 47_[-1(1.19e-06)]_37 chr17:4731337-4731837 8.99e-01 100 chr17:8226686-8227186 2.59e-07 71_[+2(1.02e-08)]_7 chr1:21345686-21346186 1.05e-07 1_[-2(4.80e-12)]_77 chr19:39436201-39436701 9.04e-01 100 chr12:21437311-21437811 4.67e-01 100 chr10:42782454-42782954 5.37e-03 73_[-2(6.02e-05)]_5 chr1:61692230-61692730 5.29e-03 3_[-1(2.63e-05)]_35_[-1(6.05e-06)]_\ 30 chr14:35121843-35122343 4.14e-02 62_[-1(7.79e-05)]_22 chr12:110048395-11004889 3.83e-01 100 chr16:84145365-84145865 1.54e-01 100 chr19:38403008-38403508 4.52e-01 100 chr19:38243750-38244250 1.82e-06 10_[-1(4.95e-07)]_74 chr12:106357575-10635807 5.80e-01 100 chr19:43798770-43799270 8.20e-01 100 chr10:88880135-88880635 1.53e-01 100 chr21:36069843-36070343 8.71e-01 100 chr1:9943155-9943655 7.61e-01 100 chr9:129824300-129824800 1.13e-16 34_[+3(1.86e-21)]_28 chr19:43934762-43935262 9.66e-01 100 chr17:7616403-7616903 1.36e-08 34_[-1(5.62e-09)]_50 chr10:120851014-12085151 4.48e-01 100 chr16:30021286-30021786 9.68e-01 100 chr1:229342693-229343193 9.67e-01 100 chr1:30488250-30488750 1.61e-04 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chr19:45439225-45439725 6.13e-01 100 chr1:230868110-230868610 6.55e-01 100 chr19:36772265-36772765 3.35e-01 100 chr21:33324331-33324831 9.68e-01 100 chr19:33797037-33797537 1.25e-07 10_[-2(4.80e-12)]_68 chr19:12806533-12807033 9.98e-01 100 chr1:150235772-150236272 5.17e-07 35_[+2(6.91e-06)]_14_[+2(2.01e-11)]_\ 7 chr6:4018174-4018674 9.95e-01 100 chr10:5889499-5889999 6.94e-01 100 chr18:11688961-11689461 3.07e-01 100 chr19:11090556-11091056 9.95e-01 100 chr19:43596373-43596873 9.13e-01 100 chr19:40443659-40444159 5.54e-01 100 chr6:85642860-85643360 3.36e-01 100 chr17:42773119-42773619 4.82e-01 100 chr6:159726789-159727289 3.71e-01 100 chr16:31179987-31180487 9.91e-01 100 chr11:113773672-11377417 1.92e-02 17_[-2(3.76e-05)]_61 chr1:27321960-27322460 1.01e-02 38_[-3(2.25e-05)]_24 chr16:85522948-85523448 6.75e-05 12_[-2(6.64e-09)]_66 chr17:30477285-30477785 2.41e-01 100 chr1:92298537-92299037 7.01e-01 100 chr21:25607268-25607768 4.44e-01 100 chr6:28795831-28796331 6.58e-02 100 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chr1:36255917-36256417 1.62e-12 28_[+1(1.69e-05)]_29_[+1(2.45e-11)]_\ 11 chr1:109484058-109484558 6.22e-01 100 chr16:3183985-3184485 7.27e-10 36_[-2(3.00e-09)]_42 chr17:59209678-59210178 5.43e-01 100 chr19:41376159-41376659 2.80e-08 76_[+1(1.31e-08)]_8 chr14:22982638-22983138 8.01e-01 100 chr6:3231621-3232121 2.44e-02 100 chr22:32472788-32473288 1.40e-26 16_[+3(1.02e-22)]_26_[-1(6.52e-08)]_\ 4 chr5:181218520-181219020 5.84e-18 42_[+3(4.19e-23)]_20 chr1:93078872-93079372 6.66e-01 100 chr16:30874977-30875477 6.63e-01 100 chr10:117541472-11754197 2.51e-02 1_[+2(6.67e-05)]_77 chr6:79078056-79078556 4.40e-01 100 chr20:52972214-52972714 2.16e-08 10_[-2(3.00e-12)]_9_[-2(1.46e-06)]_\ 37 chr17:45148393-45148893 3.73e-01 100 chr19:37594249-37594749 3.33e-02 100 chrX:73944035-73944535 9.56e-01 100 chr19:1383510-1384010 7.01e-01 100 chr21:39313556-39314056 9.99e-01 100 chr1:44213164-44213664 9.39e-01 100 chr12:54188168-54188668 4.49e-01 100 chr19:39411901-39412401 7.62e-04 5_[-2(6.91e-06)]_73 chr19:17337039-17337539 3.33e-01 100 chr11:47578724-47579224 9.23e-01 100 chrUn_KI270467v1:3122-36 6.14e-04 22_[+1(2.02e-06)]_7_[+1(6.48e-05)]_\ 3_[+1(2.02e-06)]_20 chr19:35947339-35947839 7.54e-08 58_[-2(4.80e-12)]_20 chr12:12266976-12267476 7.69e-01 100 chrUn_KI270467v1:2070-25 5.20e-04 32_[+1(2.02e-06)]_23_[+1(1.60e-05)]_\ 13 chr19:36916386-36916886 1.43e-06 58_[-2(2.62e-10)]_20 chr10:93702413-93702913 5.92e-01 100 chr1:235688752-235689252 6.04e-13 32_[-1(2.45e-11)]_2_[-1(2.45e-11)]_\ 3_[+2(1.46e-09)]_9 chr6:131628047-131628547 5.93e-01 100 chr7:102572306-102572806 9.75e-01 100 chr19:37655818-37656318 2.54e-01 100 chr5:150459727-150460227 6.93e-10 74_[+1(2.04e-08)]_10 chr19:40556267-40556767 2.03e-10 27_[+1(3.53e-07)]_[+1(2.36e-10)]_7_\ [+1(6.35e-07)]_18 chr1_KI270713v1_random:2 2.52e-12 59_[+1(9.09e-11)]_1_[-2(4.25e-09)]_\ 2 chr6:24774894-24775394 3.90e-01 100 chr19:37371123-37371623 1.47e-04 69_[-2(3.45e-08)]_9 chr12:8949986-8950486 1.38e-07 68_[+1(3.92e-08)]_16 chr19:44207464-44207964 5.99e-02 100 chr1:241357387-241357887 2.31e-10 82_[+1(2.45e-11)]_2 chr12:117189352-11718985 1.74e-11 48_[-1(3.36e-10)]_36 chr1:183471815-183472315 4.13e-01 100 chr19:35643410-35643910 7.19e-01 100 chr12:47080555-47081055 1.58e-03 2_[+1(5.85e-07)]_82 chr19:41310147-41310647 5.77e-01 100 chrUn_KI270466v1:187-687 8.22e-04 54_[+1(2.02e-06)]_30 chr1:37989799-37990299 6.31e-01 100 chr19:36488967-36489467 1.43e-03 16_[+2(5.01e-06)]_9_[+2(1.82e-05)]_\ 31 chr15:65610888-65611388 5.59e-01 100 chr19:44164465-44164965 1.74e-04 60_[+2(4.71e-07)]_18 chr1:63523036-63523536 1.00e+00 100 chr2:235741461-235741961 2.10e-12 29_[+1(9.09e-11)]_1_[-2(1.87e-09)]_\ [+1(9.09e-11)]_[+1(5.10e-05)] chr10:23411313-23411813 3.27e-13 21_[+2(1.65e-09)]_4_[-1(2.45e-11)]_\ 37 chr6:41318730-41319230 2.47e-01 100 chr1:155244209-155244709 3.05e-09 1_[-1(9.09e-11)]_83 chr8:28514878-28515378 9.11e-03 100 chrUn_KI270467v1:2907-34 5.05e-04 28_[+1(2.02e-06)]_26_[+1(3.81e-06)]_\ 14 chr12:1085293-1085793 4.70e-12 [-2(9.92e-05)]_29_[+1(1.25e-10)]_1_\ [-2(9.92e-05)]_10 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (3) found. ******************************************************************************** CPU: kadru ********************************************************************************