******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.12.0 (Release date: Tue Jun 27 16:22:50 2017 -0700) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme-suite.org . This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme-suite.org . ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/KLF17.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr17:57849943-57850443 1.0000 100 chr7:151727580-151728080 1.0000 100 chr17:7234314-7234814 1.0000 100 chr14:99274599-99275099 1.0000 100 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1.0000 100 chr17:51153296-51153796 1.0000 100 chr16:30957582-30958082 1.0000 100 chr12:131627238-13162773 1.0000 100 chr21:34845654-34846154 1.0000 100 chr1:1000656-1001156 1.0000 100 chr1:156586937-156587437 1.0000 100 chr10:121310152-12131065 1.0000 100 chr21:39313503-39314003 1.0000 100 chr10:71218031-71218531 1.0000 100 chr1:3403735-3404235 1.0000 100 chr17:74514127-74514627 1.0000 100 chr12:12266922-12267422 1.0000 100 chr19:35628752-35629252 1.0000 100 chr13:110870184-11087068 1.0000 100 chr1:3352955-3353455 1.0000 100 chr16:4944709-4945209 1.0000 100 chr3:195907748-195908248 1.0000 100 chr1:229064400-229064900 1.0000 100 chr19:35248581-35249081 1.0000 100 chr20:58650937-58651437 1.0000 100 chr17:49976145-49976645 1.0000 100 chr12:54359089-54359589 1.0000 100 chr17:42998034-42998534 1.0000 100 chr12:131627008-13162750 1.0000 100 chr12:132445991-13244649 1.0000 100 chr3:11140207-11140707 1.0000 100 chr1:183471788-183472288 1.0000 100 chr3:14452053-14452553 1.0000 100 chr15:70091903-70092403 1.0000 100 chr1:236097023-236097523 1.0000 100 chr8:37302611-37303111 1.0000 100 chr5:10551208-10551708 1.0000 100 chr9:85743161-85743661 1.0000 100 chr10:77287672-77288172 1.0000 100 chr1:41870087-41870587 1.0000 100 chr3:9731327-9731827 1.0000 100 chr1:31431809-31432309 1.0000 100 chr1:153566438-153566938 1.0000 100 chr5:124740931-124741431 1.0000 100 chr16:324364-324864 1.0000 100 chr17:83026563-83027063 1.0000 100 chr5:137516434-137516934 1.0000 100 chr19:1652602-1653102 1.0000 100 chr19:40831828-40832328 1.0000 100 chr13:110965219-11096571 1.0000 100 chr16:15590866-15591366 1.0000 100 chr2:10014220-10014720 1.0000 100 chr1:3992028-3992528 1.0000 100 chr17:7836699-7837199 1.0000 100 chr20:64030487-64030987 1.0000 100 chr1:12478120-12478620 1.0000 100 chr11:27796253-27796753 1.0000 100 chr12:124914541-12491504 1.0000 100 chr19:40920964-40921464 1.0000 100 chr1:223023039-223023539 1.0000 100 chr20:32561324-32561824 1.0000 100 chrX:70220297-70220797 1.0000 100 chr1:234723925-234724425 1.0000 100 chr8:630791-631291 1.0000 100 chr2:120515323-120515823 1.0000 100 chr3:194134814-194135314 1.0000 100 chr3:16482916-16483416 1.0000 100 chr16:12120422-12120922 1.0000 100 chr1:155244578-155245078 1.0000 100 chr1:208184303-208184803 1.0000 100 chr19:1394296-1394796 1.0000 100 chr20:16257770-16258270 1.0000 100 chr1:31387527-31388027 1.0000 100 chr20:63723002-63723502 1.0000 100 chr19:43572061-43572561 1.0000 100 chr6:168147170-168147670 1.0000 100 chr3:4986798-4987298 1.0000 100 chr17:60173295-60173795 1.0000 100 chr15:25758486-25758986 1.0000 100 chr7:155205298-155205798 1.0000 100 chr1:16122832-16123332 1.0000 100 chr10:3314556-3315056 1.0000 100 chr1:31431607-31432107 1.0000 100 chr17:3890048-3890548 1.0000 100 chr1:43423542-43424042 1.0000 100 chr17:78558298-78558798 1.0000 100 chr5:1950676-1951176 1.0000 100 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/KLF17.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/seqs-centered -oc /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/KLF17.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/meme_out -mod zoops -nmotifs 10 -minw 5 -maxw 50 -bfile /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/KLF17.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background -dna -revcomp -nostatus model: mod= zoops nmotifs= 10 evt= inf object function= E-value of product of p-values width: minw= 5 maxw= 50 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 600 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 global: substring= yes branching= no wbranch= no em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 data: n= 60000 N= 600 shuffle= -1 strands: + - sample: seed= 0 ctfrac= -1 maxwords= -1 Letter frequencies in dataset: A 0.224 C 0.276 G 0.276 T 0.224 Background letter frequencies (from /srv/scratch/shared/surya/imk1/TFBindingPredictionProject/EncodeOtherZnfData/Encode3Datahg38/KLF17.IDR0.05.filt.narrowPeak.top600.summitPlusMinus250bp.MemeChipResults/background): A 0.218 C 0.282 G 0.282 T 0.218 ******************************************************************************** ******************************************************************************** MOTIF ACACACACACACACACACACACACACACAC MEME-1 width = 30 sites = 41 llr = 805 E-value = 5.0e-124 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 Description -------------------------------------------------------------------------------- Simplified A 718:a37:9:81818:62518:917:6161 pos.-specific C 29:8:719:828:817152818:8191817 probability G 1:::::1::1::11:12121:1:1111:2: matrix T ::11::1::1:11:12111::11:1:1111 bits 2.2 2.0 1.8 * * 1.5 * * * * Relative 1.3 * * ** * * * Entropy 1.1 **** ** * * * * (28.3 bits) 0.9 ****** ******** ******* 0.7 **************** ******* * * 0.4 ***************** *********** 0.2 ****************************** 0.0 ------------------------------ Multilevel ACACACACACACACACACACACACACACAC consensus C A GA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------ chr19:35947341-35947841 - 57 6.77e-19 ACACACACAC ACACACACACACACACACACACACACACAC GAACAGTGCC chr13:98487922-98488422 + 41 6.77e-19 agatgaagac acacacacacacacacacacacacacacac acacacacac chr17:38726108-38726608 - 65 6.77e-19 AGACAG ACACACACACACACACACACACACACACAC ATGCACGCAC chr1:42165880-42166380 - 36 6.77e-19 CCCCCCCTTA ACACACACACACACACACACACACACACAC TCACCAGAAA chr5:93582525-93583025 - 47 2.25e-18 GTCTATGGTC ACACACACACACACATACACACACACACAC TTACGCTCAC chr10:101830476-10183097 + 9 1.62e-17 ACGCCcac acacacacacacacacacacacacacGCAC GCAGGCCTGG chr22:35840385-35840885 - 43 1.62e-17 CCTCCCCCCT ACACACACACACACACACACACACACGCAC ACACGCACAC chr6:37576276-37576776 - 1 3.01e-17 GGTGGAAGCA AAACACACACACACACACACACACACACAC chr7:191555-192055 + 52 1.52e-13 acacaggcat acacacgcacacgcacatccacacacacac atgcgcacac chr9:135967565-135968065 - 17 1.52e-13 GCGCGCGCGC GCGCACACACACACACACACACACACACGC CTGCACACTC chr17:45127535-45128035 - 65 2.97e-13 CTGTAC GCACACACACACTCACACGCACACACTCAC ACACATTCAC chr19:33274103-33274603 - 12 5.01e-13 TCACACGGGT ACACACACACATGCACACACAGACAGACAC AGACTCACAC chr3:194134814-194135314 + 31 3.26e-12 GCGcacacac actcactcacacacgcacgcacacacacaT CCTCCCGGCC chr20:62651982-62652482 - 36 3.67e-12 CAAGGTCCAC CCACACACACAAACACGTGCACACGCACAC ACATAAATAG chr16:88882193-88882693 - 2 5.23e-12 CCACACACAG CCATACACACACAGCCACACCCACACACAC A chr2:10014774-10015274 - 30 1.84e-11 TGCCCACCTG ACTCACCCATACACACACCCATACACACGC CTGTCCACCT chr2:43210597-43211097 + 55 7.45e-11 GCTcaccccc ccacactcacacacactcacagagccacac cacagcctca chr22:42648692-42649192 + 48 4.53e-10 ACGCTCGCTC ACACACTCACACTCAGCGGCACACACGCTC ACAACCACGG chr10:71218031-71218531 - 31 4.99e-10 ATTGCCCACC CCACACACACCCAAACACAGACACAGCCTA TACATCACAC chr16:12120422-12120922 - 35 2.40e-09 GTCCCCAGGG ACCCAAACATAAACACAGACACACAGCCAG ATGACGCACA chr17:50101365-50101865 + 41 2.62e-09 catgcacatg ccacatgcacacaattacacacacTCCCCC GCTGGCTCAG chr2:10014220-10014720 - 2 2.86e-09 TGCCCACCTG ACTCACCCATACACACACCCATATGCACGC C chr6:138088259-138088759 + 17 3.12e-09 AACTATCTCT AAATACACACACGCATGCTCACACACTTCT GAGTTTCCCT chr1:31387527-31388027 + 14 4.43e-09 ACACCCCCAG ACACATCCACACAGATGACCTCACCCACAC CCCGAGACAC chr12:48021664-48022164 + 32 4.43e-09 AATGGACCCT AAACAAACACATTAACAACCACTCAGAGAC CTAACGCTGG chr20:16257770-16258270 + 39 8.72e-09 CTTCGCAAAC ACACACACCCCTTCCCCATCACAAACACAC ACACCCTTTC chr19:36604694-36605194 + 68 1.32e-08 ggacgcagcc acagaacggcacacacaaacacaatcacac aGT chr7:28729212-28729712 - 36 3.42e-08 GGAAAGGCAA ACACAAACACACCCAGGTTGACATTCAAAA CGAAGTGGAT chr15:75023447-75023947 - 56 6.28e-08 GAAAATAAGG ACACACACAGACAGCCGTGGACCCACGCTC GCGGACACAG chr2:3296206-3296706 + 52 1.13e-07 CATCCTCTCT CCACACACACACCCTCCATCCAACCCATCC TCTCCACACA chr17:3892010-3892510 + 69 1.40e-07 GTCCTgcacc ccccacgcagacacaggcacactcccgcgt cc chr1:31937335-31937835 + 9 1.51e-07 TTCTCCCC CCACACTCACCCGCTCTTTACCACACTCTC AACTCTCTCC chr19:43572061-43572561 + 31 1.74e-07 ccctccctct acacaaacacctacatgttgacagagcact tgtgcagaca chr21:45353077-45353577 - 59 1.74e-07 CAGACCTCCC CCTTTAAAAGACACACAAACACACCCTAAT TACCTCATTT chr8:37142737-37143237 + 54 2.00e-07 AACCATGCAC TCATAAACAGCAAATGGAAAACAAACACAC TGAGCACGCC chr19:55338664-55339164 + 54 3.47e-07 ggctgTGGCG aaacaaacaaacaagcaaacaaaGACCGCC TGTTCTGAGT chr5:1950676-1951176 - 17 3.71e-07 AGAGCAGATG ACTCACGCGCCCACAGCAGACGACACACGC ATGCACAACA chr5:174503838-174504338 - 68 8.68e-07 ATT ACACAAAAATATACATTGCCCCACTGTAAT TATTCCAGAC chr1:3403735-3404235 + 68 9.25e-07 TGTTTTCTTT ACATAAACACATAAATCACAATTAACAACG GGG chr20:50165939-50166439 - 65 1.12e-06 CTCAGC ACATAATCACAAAGAGCCAAGCACGCATGA GTCAGAAGCA chr14:104137743-10413824 + 4 2.32e-06 ACG GCGCGCACACCCACTTGCGGGCACACGCGC GGCTGTAAAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:35947341-35947841 6.8e-19 56_[-1]_14 chr13:98487922-98488422 6.8e-19 40_[+1]_30 chr17:38726108-38726608 6.8e-19 64_[-1]_6 chr1:42165880-42166380 6.8e-19 35_[-1]_35 chr5:93582525-93583025 2.2e-18 46_[-1]_24 chr10:101830476-10183097 1.6e-17 8_[+1]_62 chr22:35840385-35840885 1.6e-17 42_[-1]_28 chr6:37576276-37576776 3e-17 [-1]_70 chr7:191555-192055 1.5e-13 51_[+1]_19 chr9:135967565-135968065 1.5e-13 16_[-1]_54 chr17:45127535-45128035 3e-13 64_[-1]_6 chr19:33274103-33274603 5e-13 11_[-1]_59 chr3:194134814-194135314 3.3e-12 30_[+1]_40 chr20:62651982-62652482 3.7e-12 35_[-1]_35 chr16:88882193-88882693 5.2e-12 1_[-1]_69 chr2:10014774-10015274 1.8e-11 29_[-1]_41 chr2:43210597-43211097 7.5e-11 54_[+1]_16 chr22:42648692-42649192 4.5e-10 47_[+1]_23 chr10:71218031-71218531 5e-10 30_[-1]_40 chr16:12120422-12120922 2.4e-09 34_[-1]_36 chr17:50101365-50101865 2.6e-09 40_[+1]_30 chr2:10014220-10014720 2.9e-09 1_[-1]_69 chr6:138088259-138088759 3.1e-09 16_[+1]_54 chr1:31387527-31388027 4.4e-09 13_[+1]_57 chr12:48021664-48022164 4.4e-09 31_[+1]_39 chr20:16257770-16258270 8.7e-09 38_[+1]_32 chr19:36604694-36605194 1.3e-08 67_[+1]_3 chr7:28729212-28729712 3.4e-08 35_[-1]_35 chr15:75023447-75023947 6.3e-08 55_[-1]_15 chr2:3296206-3296706 1.1e-07 51_[+1]_19 chr17:3892010-3892510 1.4e-07 68_[+1]_2 chr1:31937335-31937835 1.5e-07 8_[+1]_62 chr19:43572061-43572561 1.7e-07 30_[+1]_40 chr21:45353077-45353577 1.7e-07 58_[-1]_12 chr8:37142737-37143237 2e-07 53_[+1]_17 chr19:55338664-55339164 3.5e-07 53_[+1]_17 chr5:1950676-1951176 3.7e-07 16_[-1]_54 chr5:174503838-174504338 8.7e-07 67_[-1]_3 chr1:3403735-3404235 9.3e-07 67_[+1]_3 chr20:50165939-50166439 1.1e-06 64_[-1]_6 chr14:104137743-10413824 2.3e-06 3_[+1]_67 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACACACACACACACACACACACACACACAC width=30 seqs=41 chr19:35947341-35947841 ( 57) ACACACACACACACACACACACACACACAC 1 chr13:98487922-98488422 ( 41) ACACACACACACACACACACACACACACAC 1 chr17:38726108-38726608 ( 65) ACACACACACACACACACACACACACACAC 1 chr1:42165880-42166380 ( 36) ACACACACACACACACACACACACACACAC 1 chr5:93582525-93583025 ( 47) ACACACACACACACATACACACACACACAC 1 chr10:101830476-10183097 ( 9) ACACACACACACACACACACACACACGCAC 1 chr22:35840385-35840885 ( 43) ACACACACACACACACACACACACACGCAC 1 chr6:37576276-37576776 ( 1) AAACACACACACACACACACACACACACAC 1 chr7:191555-192055 ( 52) ACACACGCACACGCACATCCACACACACAC 1 chr9:135967565-135968065 ( 17) GCGCACACACACACACACACACACACACGC 1 chr17:45127535-45128035 ( 65) GCACACACACACTCACACGCACACACTCAC 1 chr19:33274103-33274603 ( 12) ACACACACACATGCACACACAGACAGACAC 1 chr3:194134814-194135314 ( 31) ACTCACTCACACACGCACGCACACACACAT 1 chr20:62651982-62652482 ( 36) CCACACACACAAACACGTGCACACGCACAC 1 chr16:88882193-88882693 ( 2) CCATACACACACAGCCACACCCACACACAC 1 chr2:10014774-10015274 ( 30) ACTCACCCATACACACACCCATACACACGC 1 chr2:43210597-43211097 ( 55) CCACACTCACACACACTCACAGAGCCACAC 1 chr22:42648692-42649192 ( 48) ACACACTCACACTCAGCGGCACACACGCTC 1 chr10:71218031-71218531 ( 31) CCACACACACCCAAACACAGACACAGCCTA 1 chr16:12120422-12120922 ( 35) ACCCAAACATAAACACAGACACACAGCCAG 1 chr17:50101365-50101865 ( 41) CCACATGCACACAATTACACACACTCCCCC 1 chr2:10014220-10014720 ( 2) ACTCACCCATACACACACCCATATGCACGC 1 chr6:138088259-138088759 ( 17) AAATACACACACGCATGCTCACACACTTCT 1 chr1:31387527-31388027 ( 14) ACACATCCACACAGATGACCTCACCCACAC 1 chr12:48021664-48022164 ( 32) AAACAAACACATTAACAACCACTCAGAGAC 1 chr20:16257770-16258270 ( 39) ACACACACCCCTTCCCCATCACAAACACAC 1 chr19:36604694-36605194 ( 68) ACAGAACGGCACACACAAACACAATCACAC 1 chr7:28729212-28729712 ( 36) ACACAAACACACCCAGGTTGACATTCAAAA 1 chr15:75023447-75023947 ( 56) ACACACACAGACAGCCGTGGACCCACGCTC 1 chr2:3296206-3296706 ( 52) CCACACACACACCCTCCATCCAACCCATCC 1 chr17:3892010-3892510 ( 69) CCCCACGCAGACACAGGCACACTCCCGCGT 1 chr1:31937335-31937835 ( 9) CCACACTCACCCGCTCTTTACCACACTCTC 1 chr19:43572061-43572561 ( 31) ACACAAACACCTACATGTTGACAGAGCACT 1 chr21:45353077-45353577 ( 59) CCTTTAAAAGACACACAAACACACCCTAAT 1 chr8:37142737-37143237 ( 54) TCATAAACAGCAAATGGAAAACAAACACAC 1 chr19:55338664-55339164 ( 54) AAACAAACAAACAAGCAAACAAAGACCGCC 1 chr5:1950676-1951176 ( 17) ACTCACGCGCCCACAGCAGACGACACACGC 1 chr5:174503838-174504338 ( 68) ACACAAAAATATACATTGCCCCACTGTAAT 1 chr1:3403735-3404235 ( 68) ACATAAACACATAAATCACAATTAACAACG 1 chr20:50165939-50166439 ( 65) ACATAATCACAAAGAGCCAAGCACGCATGA 1 chr14:104137743-10413824 ( 4) GCGCGCACACCCACTTGCGGGCACACGCGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 30 n= 42600 bayes= 11.5102 E= 5.0e-124 165 -36 -195 -316 -116 168 -1200 -1200 184 -253 -253 -84 -1200 156 -353 -57 213 -1200 -353 -316 30 128 -1200 -216 165 -153 -153 -84 -216 172 -353 -1200 209 -353 -253 -1200 -316 147 -153 -116 193 -72 -1200 -1200 -116 142 -1200 -57 179 -253 -153 -116 -57 142 -153 -1200 179 -195 -253 -84 -1200 122 -95 -16 136 -95 -36 -157 16 93 -195 -57 123 -72 -72 -57 -84 142 -121 -1200 188 -121 -253 -316 -216 151 -195 -157 205 -353 -1200 -157 -116 147 -195 -216 170 -121 -195 -116 -1200 160 -95 -1200 148 -121 -95 -84 -84 142 -253 -157 142 -95 -72 -116 -157 138 -253 -57 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 30 nsites= 41 E= 5.0e-124 0.682927 0.219512 0.073171 0.024390 0.097561 0.902439 0.000000 0.000000 0.780488 0.048780 0.048780 0.121951 0.000000 0.829268 0.024390 0.146341 0.951220 0.000000 0.024390 0.024390 0.268293 0.682927 0.000000 0.048780 0.682927 0.097561 0.097561 0.121951 0.048780 0.926829 0.024390 0.000000 0.926829 0.024390 0.048780 0.000000 0.024390 0.780488 0.097561 0.097561 0.829268 0.170732 0.000000 0.000000 0.097561 0.756098 0.000000 0.146341 0.756098 0.048780 0.097561 0.097561 0.146341 0.756098 0.097561 0.000000 0.756098 0.073171 0.048780 0.121951 0.000000 0.658537 0.146341 0.195122 0.560976 0.146341 0.219512 0.073171 0.243902 0.536585 0.073171 0.146341 0.512195 0.170732 0.170732 0.146341 0.121951 0.756098 0.121951 0.000000 0.804878 0.121951 0.048780 0.024390 0.048780 0.804878 0.073171 0.073171 0.902439 0.024390 0.000000 0.073171 0.097561 0.780488 0.073171 0.048780 0.707317 0.121951 0.073171 0.097561 0.000000 0.853659 0.146341 0.000000 0.609756 0.121951 0.146341 0.121951 0.121951 0.756098 0.048780 0.073171 0.585366 0.146341 0.170732 0.097561 0.073171 0.731707 0.048780 0.146341 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACACACACACACACACACACACACACACAC MEME-1 regular expression -------------------------------------------------------------------------------- [AC]CACA[CA]ACACACACAC[AG][CA]ACACACACACAC -------------------------------------------------------------------------------- Time 554.68 secs. ******************************************************************************** ******************************************************************************** MOTIF GRRGRAGGGAGGRRVR MEME-2 width = 16 sites = 136 llr = 1277 E-value = 1.1e-062 ******************************************************************************** -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 Description -------------------------------------------------------------------------------- Simplified A 153238:118:24335 pos.-specific C 11::2::::::::131 probability G 745552a89:876543 matrix T 2:121::::211:1:1 bits 2.2 2.0 1.8 * 1.5 ** * Relative 1.3 ** ** Entropy 1.1 ****** * (13.5 bits) 0.9 ******** 0.7 *** ******** 0.4 **** ******** ** 0.2 **************** 0.0 ---------------- Multilevel GAGGGAGGGAGGGGGA consensus GATA T AAACG sequence A A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------- chr19:1394296-1394796 - 15 3.59e-09 GGTCCGCAGG GAGGGAGGGAGGAGCA CGGTCCCCAA chr17:27478850-27479350 - 17 3.59e-09 GAAGAGCATG GAGGGAGGGAGGAGCA TAGATGGAGG chr17:45148341-45148841 + 19 7.76e-09 gaagggggag gagggagggaggaaaa gaggaggagg chr10:72260526-72261026 - 51 2.78e-08 AGAGGAGAGA GGGGGAGGGAGGGAGA GGCCGAGGAG chr8:142192705-142193205 + 5 3.66e-08 gcag ggaggagggaggagca gaaaggaggg chr1:234723925-234724425 + 14 6.42e-08 aatggaggga gagggagggaggaagg gaggagggag chr17:47649678-47650178 - 22 6.42e-08 GGGAGGGAGC GAGGGAGGGAGGAAGG CGGAGGGATA chr10:17201416-17201916 - 70 6.42e-08 GGAGCGGCGC GATGGAGGGAGGAGGA GCGACGGACC chr22:35840385-35840885 + 82 1.02e-07 tAGGGGGGAG GAGGTAGGGAGGGGCA AGC chr1:227906513-227907013 - 47 1.02e-07 AGGAGAGTGG GAGGGAGGGAGAGAAA GGGAGGAATA chr17:3888450-3888950 - 69 2.34e-07 ATCCAGGCGG GAGGGAGGGATGGGGA GCCTGACGTC chr17:42388527-42389027 + 53 2.34e-07 CAGAAGCCCG GGGGGAGGGAGGGAAG ATGACCGGAA chr15:25758486-25758986 - 31 5.07e-07 CAGGTGGTCG GAATGAGGGTGGAGCA GGTGATCGGA chr2:120515323-120515823 - 16 7.20e-07 GGAGGAGAGA GAGTCAGGGAGGAGGG AGAGTCCAGG chr1:40257853-40258353 + 78 1.01e-06 GCAGCGCGCA GAGGGAGGGATGGGGG CGGGTAT chr19:40602280-40602780 - 78 1.18e-06 AGGGGAG GAGAGAGGGAGTGGCA GCGGGCGGGG chr10:113063305-11306380 + 4 1.18e-06 tga gagtgagggatggaga ggagaggaga chr13:110965219-11096571 - 17 1.39e-06 TAATCAGAAT GAGTCAGGGTGGAGAA TGAGTCAGGA chr22:41022405-41022905 + 46 1.39e-06 GCCCGCGGTG GGGGCAGGGAGGGACG CGCAGCGGAG chr22:43275465-43275965 + 15 1.39e-06 aagagttctc caggaagggaggggaa tgggaaatgg chr1:26771481-26771981 + 54 1.39e-06 TAATGAATGG GAAGGAGGGAGTGGGG AAGGGTTATG chr6:29845315-29845815 - 2 1.62e-06 TGACTGGAAT GAGTCAGGGTGGAGCA G chr18:50239980-50240480 - 23 1.62e-06 TGATCAGAAT GAGTCAGGGTGGAGCA GGTAATCTGA chr1:73183529-73184029 - 12 1.62e-06 TAATGGGAAT GAGTCAGGGTGGAGCA GGTAAAGGGA chr10:110006654-11000715 + 6 1.62e-06 AAGGG GGATAAGGGTGGGGAA CGAAGTTTGT chr8:24955003-24955503 - 6 1.87e-06 AGCCCTTGTT GGGTGGGGGAGGGGAA GACGT chr22:39520210-39520710 + 29 2.18e-06 TGGGGCGTCA Aagggagggagggaag ggagcgggcg chr7:28729212-28729712 - 72 2.18e-06 TCCAGCTCGA TAATTAGGGAGGGGAA AGGCAAACAC chr4:77075966-77076466 + 31 2.52e-06 CACTAGGATG GAAGGAGGGAGGACGT TTTCTCGTGG chr5:1881187-1881687 + 1 2.52e-06 . GAGGGAGGAAGAGGGA GATAGGAAGG chr17:3679850-3680350 - 56 2.52e-06 CAGGGTGGAG GATGCAGGGTGGAGGA CGCTGGGTGG chr20:63723002-63723502 - 1 2.89e-06 CTATGACACA GGAGAAGGGAGGATGG chr17:43669979-43670479 - 64 2.89e-06 TACTGCTGGG TAAACAGGGAGGGAAA CCTGAGCTGT chr12:123601771-12360227 - 14 2.89e-06 CTCCCACGCC GCGGGAGGGAGGAAAG GCGTCCGCGG chr10:71236245-71236745 + 61 2.89e-06 ATATGAAGCC GGGGCAGGGAGGAGCT GGCTGTTAAG chr6:26285238-26285738 - 14 2.89e-06 GAAAAGGTTT GGGTAAGGGAGGAGCT AAGCGTCATC chr1:155244578-155245078 + 72 3.33e-06 gagagcgagc gagagagagagagaga gagagaggag chr21:32771748-32772248 + 2 3.33e-06 c gagagagagagagaga gagagagcga chr16:73070486-73070986 - 25 3.33e-06 ATGTGCGAGA GAGAGAGAGAGAGAGA CAATGATGTC chr22:35894887-35895387 - 4 3.33e-06 AACTCCCAGA GAGAGAGAGAGAAAGA GAG chr1:223726517-223727017 + 1 3.81e-06 . TAATAAGGGTGGGGCA TGAGTAAAAT chr10:3314556-3315056 + 6 4.35e-06 TCACA GAGTGAGGGAAGAGGA GGGTGACTTC chr19:40623658-40624158 + 25 4.35e-06 GAAGAGAAAT GGGAAAGGGTGGGGAG AGTTGAAGGG chr6:37576276-37576776 - 32 4.96e-06 ATAAGACTGG GAGGAAGGGTGGAAGC AAAACACACA chr1:156114113-156114613 - 66 4.96e-06 AAGGGTCGGG GAGAAAGAGAGGGAAG TGGGCGCAAA chr1:1426962-1427462 - 78 5.63e-06 ATGGGCG GGAGCAGGGTGGAGCG GGGAGGGGAG chr2:96638171-96638671 + 28 5.63e-06 GGTTACGGCC TGGGAAGGGAGAGGCG GTGAGCGGCA chr1:227946203-227946703 - 44 5.63e-06 ACCCGGGAGG GCAGGAGGGAGGGCCA CAGGTCCGCG chr5:93582525-93583025 - 12 6.38e-06 CACCCCAGAG GGGGAAGGGATGACGA GGGGGAGAAC chr19:11018117-11018617 - 52 6.38e-06 ACCAGGGCTG GAATGAGGGAGGACAT GGGGGCAGGC chr1:109099974-109100474 + 23 8.15e-06 TCCGCTGTTT TAGGGAGGGAGAGCGG CCTGGGTCCT chr1:228647614-228648114 + 69 8.15e-06 GACCAAACGG TAAAGAGGGAGGAACT TGAAGTCTAA chr12:63419065-63419565 - 4 1.03e-05 TAATCGGAAT GAGTCAGAGTGGAGCA GGG chr1:17603250-17603750 - 34 1.03e-05 AACTGGGAGG GAAGTGGGGAGAGAGA GCACCACCGT chr6:33758745-33759245 + 83 1.03e-05 tgtaagtaca gaggcaggatggggga gg chr1:6491410-6491910 - 31 1.16e-05 AGGCCCCCAT GGAGAAGGGACGGGCA GGATGTGAGT chr10:131385393-13138589 + 9 1.16e-05 gagggagg agtagagggaggagca gagggatgag chr6:31877262-31877762 - 5 1.16e-05 CCCTGGGGAG GGATTAGGGAGGAGGC AGGG chr12:89352479-89352979 + 22 1.16e-05 AGCGGGCTCG GCGggaggaaggagaa agaaggggag chr12:6765974-6766474 - 2 1.16e-05 AGCTAGGGAG TCGGGAGGGAGGACGA G chr9:131735349-131735849 + 22 1.30e-05 aatccctgat gaatgaGGGATGGAGT AATGAGTCAA chr17:76029355-76029855 - 6 1.30e-05 GAGGGCTTCT GAAGAGGGGAGGAAGC TCGAG chr1:175841755-175842255 + 61 1.30e-05 GCTCTGCTCT TAATGAGAGAGGAAAG CCCCACCAGG chr5:174503838-174504338 + 38 1.30e-05 GGGATCAAAA TGAAAAGGGAGAAGGG GGGGGTCTGG chr10:129440217-12944071 - 17 1.45e-05 AAGTGGGTGA GGTAGAGGGAGGATGG TGTCATCGTA chr10:72354671-72355171 + 44 1.45e-05 CCAGAACGCG GAACCAGGGAGGGGGA GGCCGGGCGA chr1:32817145-32817645 + 62 1.45e-05 GCAGCGGCCG GAAAAAGTGAGGAGCA GCAGAGAGTC chr17:21359020-21359520 - 4 1.80e-05 CTTCATCTAG GAAATGGGGAGAAGAA TGG chr20:3811635-3812135 + 57 1.80e-05 CCTGGGGCAG CAGGAAGGGAGGGGCC TCACGTGGCT chr6:52503860-52504360 - 43 1.80e-05 GCTAGGTGGG GGGTAGGGGTGGGACA CTTATCCTTT chr1:25998139-25998639 - 50 1.80e-05 GAGGACTATT TGAGGAGGGTGAGGCG GAGGGTTACG chr1:208184303-208184803 + 31 1.99e-05 GGGTTGGGTG TAGGCAGGGATGGAAG GGGCACACAG chr17:7836699-7837199 - 77 1.99e-05 TAAGACCA CGGGAAGGGAGAGGGG AAAGAGATGG chr1:3352295-3352795 - 25 2.21e-05 AGGCTGGGCC CGTGGAGGGAGAAGAA AGGGAAAGGA chr19:1262471-1262971 - 52 2.21e-05 GGAAGCAGGG GAGGGACGGAGGGGCG GAGATGGTGG chr2:197499733-197500233 - 53 2.21e-05 ACACCCTGCG CGGGTAGGGAGGGGCG GGGCTCGCGC chr1:44237983-44238483 - 2 2.21e-05 AGGGTGGCTC TGGTGGGGGAGGGAGG C chr1:67831915-67832415 + 8 2.21e-05 AAAGACA GCAGGGGGGAGAGGAA GTAACTGATG chr12:131627238-13162773 - 4 2.71e-05 GTCTCGGGCG GATGGGGAGAGGGGAG TGG chr3:131795283-131795783 - 64 2.99e-05 TGTTAAAACC ACAAAAGGGAGGGGCA GTCATTACTG chr10:129525297-12952579 - 44 2.99e-05 GAGCCCTGGG GAATTAGGGATGGTCA AAGAATGAGC chr1:26695397-26695897 - 10 2.99e-05 CTTCACAAAG GAGGAGGGGAGAGAAC AAGCCGCGG chr1:31937335-31937835 - 43 2.99e-05 ATGAGTGAGT AAATGGGGGAGGAGAG AGTTGAGAGT chr10:121613407-12161390 - 8 2.99e-05 GGGCCAGGGA GCATCAGGGAGGGCCA GGGAGCA chrX:115892920-115893420 - 25 3.29e-05 CTCAGCAAAG GGTGGAGGGAGTGGAC CTGGGGGAAG chr5:137516434-137516934 + 51 3.62e-05 TTCAGGAGAG GGGGCAGGGATAATGA CAGGCAAGTT chr22:49970676-49971176 - 40 3.62e-05 CCTTTGAGTG AAGGGAGGGTGAGTCA CGCGGTGGCA chr22:32539579-32540079 + 64 3.62e-05 AAGCTCAAAC AATGAAGAGAGGAGGG AAATGATATC chr1:229221162-229221662 - 75 3.98e-05 GCTGTCGTGG GGGTGAGTGTGGGGCA GGGACGGCAG chr11:64854878-64855378 - 22 3.98e-05 CACCCTGCGT GGTGGGGGGAGGGCAG GGCCATGCCA chr11:27796253-27796753 + 5 4.37e-05 CAGA AGGGAGGGGAGGGCGA GAAGGCAGAG chr1:156586937-156587437 - 55 4.37e-05 CTAAGCACCT AGAATAGGGTGGGGCA TGAGCTAAGC chr1:155127111-155127611 + 62 4.37e-05 CAGCCGCGTG TGTGTGGGGAGGGGCA GTCAAGCGCA chr13:98487922-98488422 + 24 4.37e-05 gctggtgtca taaaaagagatgaaga cacacacaca chrX:70220297-70220797 - 39 4.78e-05 AGATCTCGGA GATAAAGAGTGAGGCA TCTCCCAGAC chr5:124740931-124741431 + 35 4.78e-05 TTTGTTCACG TATTAAGGGAGTGGCG ACTTTTACAA chr7:44306668-44307168 + 11 4.78e-05 GTGAGCAGGA GGAGGAGGGTGTGAGC AGGAAGACGG chr1:46719610-46720110 + 17 4.78e-05 ttatttatac tctagagggaggagag caacaatagg chr16:30052839-30053339 + 10 4.78e-05 GGGAGGCGC GAGGCGGGAAGAGGGA GTTTGGGCCT chr7:44306925-44307425 + 59 5.23e-05 GAGGAGGGTG TGAGCAGAGAGAGGAG GGTGTGAACA chr13:40770960-40771460 - 41 5.23e-05 CAGGCCGGAA GCGGAAGAGAGGGCGG GGACGTGTTT chr1:175470966-175471466 - 34 5.23e-05 AGCACAGAGA TGGGCAGGGAAGGACA TAAATGAGTT chr17:83089755-83090255 - 25 5.23e-05 GGACGGCCGA GGGGGAGGATGGAGAC GCTGCCCTCA chr12:26274553-26275053 + 75 5.23e-05 CTCCTTCTCG GGAGGAGGATGTGGAA CCGTTTTGTG chr17:48577409-48577909 + 20 5.23e-05 GTGAGAATGG TGAAGAGGATGGGGAA CCTACTTCAA chr17:51046593-51047093 - 36 5.23e-05 CTATGGTTAT GAGGTGGGGAGAACGG AATGACGTCA chr12:131627008-13162750 - 59 5.72e-05 GGGCGGATGG GGAGAAGAGAGTGGCT GTGGTCTCTG chr1:159916181-159916681 + 34 5.72e-05 aagccttcct gaatgagagataaagg ATCTAATCCC chr17:34616058-34616558 + 50 5.72e-05 GCCAAGCATG GGGGTGGGGTGGATAA CAGTACTGGG chr14:103520994-10352149 + 26 6.23e-05 GCGGAGGTAG CGGGGAGGGAGGACGC CGCGAGAGGG chr12:54359089-54359589 + 78 6.79e-05 AAGAGACAGC GAAAGAGAGAGAGCGT GCGAACG chr19:38636838-38637338 - 75 6.79e-05 AGGTAGGGTG GGGCAAGGGAGGAAGT CGAAGCAGGG chr19:43639925-43640425 + 61 7.39e-05 CTTGCGCTGC GCGGAGGGGAGGGTGG CAGGGTGTTG chr14:22982564-22983064 + 75 7.39e-05 AAGAGTGTGG GGGTAGGGGACGGGGA CTCTTTGTCT chr12:51371398-51371898 + 37 7.39e-05 TGGAGTGTGC CAGACAGGGAGGGAAC CCTGGCTGCT chr6:41532247-41532747 + 1 8.03e-05 . GCAGGAGGGTGTGCGA AGGGGTGTGA chr6:125812676-125813176 - 54 8.03e-05 TGACATAGAA AGAGGAGGGATGGACT CAAGAAATAC chr1:41870087-41870587 - 62 8.72e-05 ATTGCAACGT TGAAAAGAGAGAGTGA TAAGTCGAAT chr1:31431809-31432309 + 71 9.46e-05 gtggacaggg tggttagggtggacag ggtggacagg chr1:229064400-229064900 + 60 9.46e-05 TTTGTTTTTA TGTTTAGGGTGAGGCA AGGCCTGACA chr9:126791449-126791949 + 69 9.46e-05 tacaaaggta taaacagggattaaga aaagcaacag chr3:123431547-123432047 - 5 9.46e-05 TGCAGGCGTG TAAGAGGGGAAGAAAA CTTG chr10:101830476-10183097 - 53 1.02e-04 GCACGCCTGC GTGTGGGGGAGGGGCG TGCCCCAGGC chr20:3173059-3173559 - 45 1.02e-04 AAGGGGGAGG GGAGCGGAGAGGAGGC GGATGATGTC chr1:31431607-31432107 + 12 1.11e-04 gtggacaggg tggatagggtggatag ggtggatagg chr1:183471788-183472288 + 10 1.11e-04 GGAGGAACT GTAGGAGGAAGGGGCG GCGTTTCCGG chr12:132240868-13224136 - 21 1.20e-04 GTGTGTAATG GGTATAGGGAGGGCCC CGGGAAGGGT chr3:14879341-14879841 - 43 1.20e-04 TTTGTTGACT GAAAGAGTGAGTGAGG AGTGAGTGAG chr17:77233792-77234292 + 81 1.29e-04 CATTCTGACA AATAGAGGGATGAGGT CAGC chr2:3296206-3296706 - 21 1.29e-04 GGATGGGCTG GATGGAGGGTGTGTGT TTGCAGAGGG chr6:158644249-158644749 - 17 1.39e-04 CCCGGCGCGG GGGGCGGGAAGGGGAT TGAGCTTCTT chr17:51153296-51153796 + 7 1.50e-04 TCCCAA GAGGAAGCGTGGGCGA GCGGTGTTCT chr11:66001985-66002485 - 16 1.50e-04 GACCTGGCGT GGGGAAGAGTTAGAAG ACGGACAAGG chr19:40831828-40832328 - 14 1.61e-04 TACCAAGGAC GGGTGGGGGAAGGTAA TAAGAAGCCC chr10:93702418-93702918 + 85 1.61e-04 AGAAACGGCC CGGAAAGGGACGAAGA chr20:58650937-58651437 + 62 2.79e-04 GGGCACTCGC GAGGGACGGACAGGAA GAGGGCCAGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:1394296-1394796 3.6e-09 14_[-2]_70 chr17:27478850-27479350 3.6e-09 16_[-2]_68 chr17:45148341-45148841 7.8e-09 18_[+2]_66 chr10:72260526-72261026 2.8e-08 50_[-2]_34 chr8:142192705-142193205 3.7e-08 4_[+2]_80 chr1:234723925-234724425 6.4e-08 13_[+2]_71 chr17:47649678-47650178 6.4e-08 21_[-2]_63 chr10:17201416-17201916 6.4e-08 69_[-2]_15 chr22:35840385-35840885 1e-07 81_[+2]_3 chr1:227906513-227907013 1e-07 46_[-2]_38 chr17:3888450-3888950 2.3e-07 68_[-2]_16 chr17:42388527-42389027 2.3e-07 52_[+2]_32 chr15:25758486-25758986 5.1e-07 30_[-2]_54 chr2:120515323-120515823 7.2e-07 15_[-2]_69 chr1:40257853-40258353 1e-06 77_[+2]_7 chr19:40602280-40602780 1.2e-06 77_[-2]_7 chr10:113063305-11306380 1.2e-06 3_[+2]_81 chr13:110965219-11096571 1.4e-06 16_[-2]_68 chr22:41022405-41022905 1.4e-06 45_[+2]_39 chr22:43275465-43275965 1.4e-06 14_[+2]_70 chr1:26771481-26771981 1.4e-06 53_[+2]_31 chr6:29845315-29845815 1.6e-06 1_[-2]_83 chr18:50239980-50240480 1.6e-06 22_[-2]_62 chr1:73183529-73184029 1.6e-06 11_[-2]_73 chr10:110006654-11000715 1.6e-06 5_[+2]_79 chr8:24955003-24955503 1.9e-06 5_[-2]_79 chr22:39520210-39520710 2.2e-06 28_[+2]_56 chr7:28729212-28729712 2.2e-06 71_[-2]_13 chr4:77075966-77076466 2.5e-06 30_[+2]_54 chr5:1881187-1881687 2.5e-06 [+2]_84 chr17:3679850-3680350 2.5e-06 55_[-2]_29 chr20:63723002-63723502 2.9e-06 [-2]_84 chr17:43669979-43670479 2.9e-06 63_[-2]_21 chr12:123601771-12360227 2.9e-06 13_[-2]_71 chr10:71236245-71236745 2.9e-06 60_[+2]_24 chr6:26285238-26285738 2.9e-06 13_[-2]_71 chr1:155244578-155245078 3.3e-06 71_[+2]_13 chr21:32771748-32772248 3.3e-06 1_[+2]_83 chr16:73070486-73070986 3.3e-06 24_[-2]_60 chr22:35894887-35895387 3.3e-06 3_[-2]_81 chr1:223726517-223727017 3.8e-06 [+2]_84 chr10:3314556-3315056 4.4e-06 5_[+2]_79 chr19:40623658-40624158 4.4e-06 24_[+2]_60 chr6:37576276-37576776 5e-06 31_[-2]_53 chr1:156114113-156114613 5e-06 65_[-2]_19 chr1:1426962-1427462 5.6e-06 77_[-2]_7 chr2:96638171-96638671 5.6e-06 27_[+2]_57 chr1:227946203-227946703 5.6e-06 43_[-2]_41 chr5:93582525-93583025 6.4e-06 11_[-2]_73 chr19:11018117-11018617 6.4e-06 51_[-2]_33 chr1:109099974-109100474 8.1e-06 22_[+2]_62 chr1:228647614-228648114 8.1e-06 68_[+2]_16 chr12:63419065-63419565 1e-05 3_[-2]_81 chr1:17603250-17603750 1e-05 33_[-2]_51 chr6:33758745-33759245 1e-05 82_[+2]_2 chr1:6491410-6491910 1.2e-05 30_[-2]_54 chr10:131385393-13138589 1.2e-05 8_[+2]_76 chr6:31877262-31877762 1.2e-05 4_[-2]_80 chr12:89352479-89352979 1.2e-05 21_[+2]_63 chr12:6765974-6766474 1.2e-05 1_[-2]_83 chr9:131735349-131735849 1.3e-05 21_[+2]_63 chr17:76029355-76029855 1.3e-05 5_[-2]_79 chr1:175841755-175842255 1.3e-05 60_[+2]_24 chr5:174503838-174504338 1.3e-05 37_[+2]_47 chr10:129440217-12944071 1.4e-05 16_[-2]_68 chr10:72354671-72355171 1.4e-05 43_[+2]_41 chr1:32817145-32817645 1.4e-05 61_[+2]_23 chr17:21359020-21359520 1.8e-05 3_[-2]_81 chr20:3811635-3812135 1.8e-05 56_[+2]_28 chr6:52503860-52504360 1.8e-05 42_[-2]_42 chr1:25998139-25998639 1.8e-05 49_[-2]_35 chr1:208184303-208184803 2e-05 30_[+2]_54 chr17:7836699-7837199 2e-05 76_[-2]_8 chr1:3352295-3352795 2.2e-05 24_[-2]_60 chr19:1262471-1262971 2.2e-05 51_[-2]_33 chr2:197499733-197500233 2.2e-05 52_[-2]_32 chr1:44237983-44238483 2.2e-05 1_[-2]_83 chr1:67831915-67832415 2.2e-05 7_[+2]_77 chr12:131627238-13162773 2.7e-05 3_[-2]_81 chr3:131795283-131795783 3e-05 63_[-2]_21 chr10:129525297-12952579 3e-05 43_[-2]_41 chr1:26695397-26695897 3e-05 9_[-2]_75 chr1:31937335-31937835 3e-05 42_[-2]_42 chr10:121613407-12161390 3e-05 7_[-2]_77 chrX:115892920-115893420 3.3e-05 24_[-2]_60 chr5:137516434-137516934 3.6e-05 50_[+2]_34 chr22:49970676-49971176 3.6e-05 39_[-2]_45 chr22:32539579-32540079 3.6e-05 63_[+2]_21 chr1:229221162-229221662 4e-05 74_[-2]_10 chr11:64854878-64855378 4e-05 21_[-2]_63 chr11:27796253-27796753 4.4e-05 4_[+2]_80 chr1:156586937-156587437 4.4e-05 54_[-2]_30 chr1:155127111-155127611 4.4e-05 61_[+2]_23 chr13:98487922-98488422 4.4e-05 23_[+2]_61 chrX:70220297-70220797 4.8e-05 38_[-2]_46 chr5:124740931-124741431 4.8e-05 34_[+2]_50 chr7:44306668-44307168 4.8e-05 10_[+2]_74 chr1:46719610-46720110 4.8e-05 16_[+2]_68 chr16:30052839-30053339 4.8e-05 9_[+2]_75 chr7:44306925-44307425 5.2e-05 58_[+2]_26 chr13:40770960-40771460 5.2e-05 40_[-2]_44 chr1:175470966-175471466 5.2e-05 33_[-2]_51 chr17:83089755-83090255 5.2e-05 24_[-2]_60 chr12:26274553-26275053 5.2e-05 74_[+2]_10 chr17:48577409-48577909 5.2e-05 19_[+2]_65 chr17:51046593-51047093 5.2e-05 35_[-2]_49 chr12:131627008-13162750 5.7e-05 58_[-2]_26 chr1:159916181-159916681 5.7e-05 33_[+2]_51 chr17:34616058-34616558 5.7e-05 49_[+2]_35 chr14:103520994-10352149 6.2e-05 25_[+2]_59 chr12:54359089-54359589 6.8e-05 77_[+2]_7 chr19:38636838-38637338 6.8e-05 74_[-2]_10 chr19:43639925-43640425 7.4e-05 60_[+2]_24 chr14:22982564-22983064 7.4e-05 74_[+2]_10 chr12:51371398-51371898 7.4e-05 36_[+2]_48 chr6:41532247-41532747 8e-05 [+2]_84 chr6:125812676-125813176 8e-05 53_[-2]_31 chr1:41870087-41870587 8.7e-05 61_[-2]_23 chr1:31431809-31432309 9.5e-05 70_[+2]_14 chr1:229064400-229064900 9.5e-05 59_[+2]_25 chr9:126791449-126791949 9.5e-05 68_[+2]_16 chr3:123431547-123432047 9.5e-05 4_[-2]_80 chr10:101830476-10183097 0.0001 52_[-2]_32 chr20:3173059-3173559 0.0001 44_[-2]_40 chr1:31431607-31432107 0.00011 11_[+2]_73 chr1:183471788-183472288 0.00011 9_[+2]_75 chr12:132240868-13224136 0.00012 20_[-2]_64 chr3:14879341-14879841 0.00012 42_[-2]_42 chr17:77233792-77234292 0.00013 80_[+2]_4 chr2:3296206-3296706 0.00013 20_[-2]_64 chr6:158644249-158644749 0.00014 16_[-2]_68 chr17:51153296-51153796 0.00015 6_[+2]_78 chr11:66001985-66002485 0.00015 15_[-2]_69 chr19:40831828-40832328 0.00016 13_[-2]_71 chr10:93702418-93702918 0.00016 84_[+2] chr20:58650937-58651437 0.00028 61_[+2]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GRRGRAGGGAGGRRVR width=16 seqs=136 chr19:1394296-1394796 ( 15) GAGGGAGGGAGGAGCA 1 chr17:27478850-27479350 ( 17) GAGGGAGGGAGGAGCA 1 chr17:45148341-45148841 ( 19) GAGGGAGGGAGGAAAA 1 chr10:72260526-72261026 ( 51) GGGGGAGGGAGGGAGA 1 chr8:142192705-142193205 ( 5) GGAGGAGGGAGGAGCA 1 chr1:234723925-234724425 ( 14) GAGGGAGGGAGGAAGG 1 chr17:47649678-47650178 ( 22) GAGGGAGGGAGGAAGG 1 chr10:17201416-17201916 ( 70) GATGGAGGGAGGAGGA 1 chr22:35840385-35840885 ( 82) GAGGTAGGGAGGGGCA 1 chr1:227906513-227907013 ( 47) GAGGGAGGGAGAGAAA 1 chr17:3888450-3888950 ( 69) GAGGGAGGGATGGGGA 1 chr17:42388527-42389027 ( 53) GGGGGAGGGAGGGAAG 1 chr15:25758486-25758986 ( 31) GAATGAGGGTGGAGCA 1 chr2:120515323-120515823 ( 16) GAGTCAGGGAGGAGGG 1 chr1:40257853-40258353 ( 78) GAGGGAGGGATGGGGG 1 chr19:40602280-40602780 ( 78) GAGAGAGGGAGTGGCA 1 chr10:113063305-11306380 ( 4) GAGTGAGGGATGGAGA 1 chr13:110965219-11096571 ( 17) GAGTCAGGGTGGAGAA 1 chr22:41022405-41022905 ( 46) GGGGCAGGGAGGGACG 1 chr22:43275465-43275965 ( 15) CAGGAAGGGAGGGGAA 1 chr1:26771481-26771981 ( 54) GAAGGAGGGAGTGGGG 1 chr6:29845315-29845815 ( 2) GAGTCAGGGTGGAGCA 1 chr18:50239980-50240480 ( 23) GAGTCAGGGTGGAGCA 1 chr1:73183529-73184029 ( 12) GAGTCAGGGTGGAGCA 1 chr10:110006654-11000715 ( 6) GGATAAGGGTGGGGAA 1 chr8:24955003-24955503 ( 6) GGGTGGGGGAGGGGAA 1 chr22:39520210-39520710 ( 29) AAGGGAGGGAGGGAAG 1 chr7:28729212-28729712 ( 72) TAATTAGGGAGGGGAA 1 chr4:77075966-77076466 ( 31) GAAGGAGGGAGGACGT 1 chr5:1881187-1881687 ( 1) GAGGGAGGAAGAGGGA 1 chr17:3679850-3680350 ( 56) GATGCAGGGTGGAGGA 1 chr20:63723002-63723502 ( 1) GGAGAAGGGAGGATGG 1 chr17:43669979-43670479 ( 64) TAAACAGGGAGGGAAA 1 chr12:123601771-12360227 ( 14) GCGGGAGGGAGGAAAG 1 chr10:71236245-71236745 ( 61) GGGGCAGGGAGGAGCT 1 chr6:26285238-26285738 ( 14) GGGTAAGGGAGGAGCT 1 chr1:155244578-155245078 ( 72) GAGAGAGAGAGAGAGA 1 chr21:32771748-32772248 ( 2) GAGAGAGAGAGAGAGA 1 chr16:73070486-73070986 ( 25) GAGAGAGAGAGAGAGA 1 chr22:35894887-35895387 ( 4) GAGAGAGAGAGAAAGA 1 chr1:223726517-223727017 ( 1) TAATAAGGGTGGGGCA 1 chr10:3314556-3315056 ( 6) GAGTGAGGGAAGAGGA 1 chr19:40623658-40624158 ( 25) GGGAAAGGGTGGGGAG 1 chr6:37576276-37576776 ( 32) GAGGAAGGGTGGAAGC 1 chr1:156114113-156114613 ( 66) GAGAAAGAGAGGGAAG 1 chr1:1426962-1427462 ( 78) GGAGCAGGGTGGAGCG 1 chr2:96638171-96638671 ( 28) TGGGAAGGGAGAGGCG 1 chr1:227946203-227946703 ( 44) GCAGGAGGGAGGGCCA 1 chr5:93582525-93583025 ( 12) GGGGAAGGGATGACGA 1 chr19:11018117-11018617 ( 52) GAATGAGGGAGGACAT 1 chr1:109099974-109100474 ( 23) TAGGGAGGGAGAGCGG 1 chr1:228647614-228648114 ( 69) TAAAGAGGGAGGAACT 1 chr12:63419065-63419565 ( 4) GAGTCAGAGTGGAGCA 1 chr1:17603250-17603750 ( 34) GAAGTGGGGAGAGAGA 1 chr6:33758745-33759245 ( 83) GAGGCAGGATGGGGGA 1 chr1:6491410-6491910 ( 31) GGAGAAGGGACGGGCA 1 chr10:131385393-13138589 ( 9) AGTAGAGGGAGGAGCA 1 chr6:31877262-31877762 ( 5) GGATTAGGGAGGAGGC 1 chr12:89352479-89352979 ( 22) GCGGGAGGAAGGAGAA 1 chr12:6765974-6766474 ( 2) TCGGGAGGGAGGACGA 1 chr9:131735349-131735849 ( 22) GAATGAGGGATGGAGT 1 chr17:76029355-76029855 ( 6) GAAGAGGGGAGGAAGC 1 chr1:175841755-175842255 ( 61) TAATGAGAGAGGAAAG 1 chr5:174503838-174504338 ( 38) TGAAAAGGGAGAAGGG 1 chr10:129440217-12944071 ( 17) GGTAGAGGGAGGATGG 1 chr10:72354671-72355171 ( 44) GAACCAGGGAGGGGGA 1 chr1:32817145-32817645 ( 62) GAAAAAGTGAGGAGCA 1 chr17:21359020-21359520 ( 4) GAAATGGGGAGAAGAA 1 chr20:3811635-3812135 ( 57) CAGGAAGGGAGGGGCC 1 chr6:52503860-52504360 ( 43) GGGTAGGGGTGGGACA 1 chr1:25998139-25998639 ( 50) TGAGGAGGGTGAGGCG 1 chr1:208184303-208184803 ( 31) TAGGCAGGGATGGAAG 1 chr17:7836699-7837199 ( 77) CGGGAAGGGAGAGGGG 1 chr1:3352295-3352795 ( 25) CGTGGAGGGAGAAGAA 1 chr19:1262471-1262971 ( 52) GAGGGACGGAGGGGCG 1 chr2:197499733-197500233 ( 53) CGGGTAGGGAGGGGCG 1 chr1:44237983-44238483 ( 2) TGGTGGGGGAGGGAGG 1 chr1:67831915-67832415 ( 8) GCAGGGGGGAGAGGAA 1 chr12:131627238-13162773 ( 4) GATGGGGAGAGGGGAG 1 chr3:131795283-131795783 ( 64) ACAAAAGGGAGGGGCA 1 chr10:129525297-12952579 ( 44) GAATTAGGGATGGTCA 1 chr1:26695397-26695897 ( 10) GAGGAGGGGAGAGAAC 1 chr1:31937335-31937835 ( 43) AAATGGGGGAGGAGAG 1 chr10:121613407-12161390 ( 8) GCATCAGGGAGGGCCA 1 chrX:115892920-115893420 ( 25) GGTGGAGGGAGTGGAC 1 chr5:137516434-137516934 ( 51) GGGGCAGGGATAATGA 1 chr22:49970676-49971176 ( 40) AAGGGAGGGTGAGTCA 1 chr22:32539579-32540079 ( 64) AATGAAGAGAGGAGGG 1 chr1:229221162-229221662 ( 75) GGGTGAGTGTGGGGCA 1 chr11:64854878-64855378 ( 22) GGTGGGGGGAGGGCAG 1 chr11:27796253-27796753 ( 5) AGGGAGGGGAGGGCGA 1 chr1:156586937-156587437 ( 55) AGAATAGGGTGGGGCA 1 chr1:155127111-155127611 ( 62) TGTGTGGGGAGGGGCA 1 chr13:98487922-98488422 ( 24) TAAAAAGAGATGAAGA 1 chrX:70220297-70220797 ( 39) GATAAAGAGTGAGGCA 1 chr5:124740931-124741431 ( 35) TATTAAGGGAGTGGCG 1 chr7:44306668-44307168 ( 11) GGAGGAGGGTGTGAGC 1 chr1:46719610-46720110 ( 17) TCTAGAGGGAGGAGAG 1 chr16:30052839-30053339 ( 10) GAGGCGGGAAGAGGGA 1 chr7:44306925-44307425 ( 59) TGAGCAGAGAGAGGAG 1 chr13:40770960-40771460 ( 41) GCGGAAGAGAGGGCGG 1 chr1:175470966-175471466 ( 34) TGGGCAGGGAAGGACA 1 chr17:83089755-83090255 ( 25) GGGGGAGGATGGAGAC 1 chr12:26274553-26275053 ( 75) GGAGGAGGATGTGGAA 1 chr17:48577409-48577909 ( 20) TGAAGAGGATGGGGAA 1 chr17:51046593-51047093 ( 36) GAGGTGGGGAGAACGG 1 chr12:131627008-13162750 ( 59) GGAGAAGAGAGTGGCT 1 chr1:159916181-159916681 ( 34) GAATGAGAGATAAAGG 1 chr17:34616058-34616558 ( 50) GGGGTGGGGTGGATAA 1 chr14:103520994-10352149 ( 26) CGGGGAGGGAGGACGC 1 chr12:54359089-54359589 ( 78) GAAAGAGAGAGAGCGT 1 chr19:38636838-38637338 ( 75) GGGCAAGGGAGGAAGT 1 chr19:43639925-43640425 ( 61) GCGGAGGGGAGGGTGG 1 chr14:22982564-22983064 ( 75) GGGTAGGGGACGGGGA 1 chr12:51371398-51371898 ( 37) CAGACAGGGAGGGAAC 1 chr6:41532247-41532747 ( 1) GCAGGAGGGTGTGCGA 1 chr6:125812676-125813176 ( 54) AGAGGAGGGATGGACT 1 chr1:41870087-41870587 ( 62) TGAAAAGAGAGAGTGA 1 chr1:31431809-31432309 ( 71) TGGTTAGGGTGGACAG 1 chr1:229064400-229064900 ( 60) TGTTTAGGGTGAGGCA 1 chr9:126791449-126791949 ( 69) TAAACAGGGATTAAGA 1 chr3:123431547-123432047 ( 5) TAAGAGGGGAAGAAAA 1 chr10:101830476-10183097 ( 53) GTGTGGGGGAGGGGCG 1 chr20:3173059-3173559 ( 45) GGAGCGGAGAGGAGGC 1 chr1:31431607-31432107 ( 12) TGGATAGGGTGGATAG 1 chr1:183471788-183472288 ( 10) GTAGGAGGAAGGGGCG 1 chr12:132240868-13224136 ( 21) GGTATAGGGAGGGCCC 1 chr3:14879341-14879841 ( 43) GAAAGAGTGAGTGAGG 1 chr17:77233792-77234292 ( 81) AATAGAGGGATGAGGT 1 chr2:3296206-3296706 ( 21) GATGGAGGGTGTGTGT 1 chr6:158644249-158644749 ( 17) GGGGCGGGAAGGGGAT 1 chr17:51153296-51153796 ( 7) GAGGAAGCGTGGGCGA 1 chr11:66001985-66002485 ( 16) GGGGAAGAGTTAGAAG 1 chr19:40831828-40832328 ( 14) GGGTGGGGGAAGGTAA 1 chr10:93702418-93702918 ( 85) CGGAAAGGGACGAAGA 1 chr20:58650937-58651437 ( 62) GAGGGACGGACAGGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 16 n= 51000 bayes= 9.91425 E= 1.1e-062 -157 -226 128 -25 124 -180 47 -389 63 -1373 93 -80 -3 -426 95 6 20 -74 74 -98 193 -1373 -74 -1373 -1373 -426 180 -1373 -64 -526 156 -330 -172 -1373 173 -1373 182 -1373 -1373 6 -289 -326 157 -108 -8 -1373 134 -143 92 -1373 106 -1373 36 -117 87 -143 40 13 52 -1373 124 -168 10 -119 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 16 nsites= 136 E= 1.1e-062 0.073529 0.058824 0.683824 0.183824 0.514706 0.080882 0.389706 0.014706 0.338235 0.000000 0.536765 0.125000 0.213235 0.014706 0.544118 0.227941 0.250000 0.169118 0.470588 0.110294 0.830882 0.000000 0.169118 0.000000 0.000000 0.014706 0.985294 0.000000 0.139706 0.007353 0.830882 0.022059 0.066176 0.000000 0.933824 0.000000 0.772059 0.000000 0.000000 0.227941 0.029412 0.029412 0.838235 0.102941 0.205882 0.000000 0.713235 0.080882 0.411765 0.000000 0.588235 0.000000 0.279412 0.125000 0.514706 0.080882 0.286765 0.308824 0.404412 0.000000 0.514706 0.088235 0.301471 0.095588 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRRGRAGGGAGGRRVR MEME-2 regular expression -------------------------------------------------------------------------------- G[AG][GA][GTA][GA]AGGG[AT]G[GA][GA][GA][GCA][AG] -------------------------------------------------------------------------------- Time 1039.21 secs. ******************************************************************************** ******************************************************************************** MOTIF TGAGTCA MEME-3 width = 7 sites = 103 llr = 984 E-value = 8.5e-058 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::9:::a pos.-specific C :::::a: probability G :a:a::: matrix T a:1:a:: bits 2.2 * * * 2.0 * * * 1.8 ******* 1.5 ******* Relative 1.3 ******* Entropy 1.1 ******* (13.8 bits) 0.9 ******* 0.7 ******* 0.4 ******* 0.2 ******* 0.0 ------- Multilevel TGAGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------- chr17:3890048-3890548 - 90 5.06e-05 GTGC TGAGTCA GGCAACAGCC chr8:630791-631291 - 27 5.06e-05 CGGGAGGGTG TGAGTCA GCTCTGTCCA chr19:40920964-40921464 + 33 5.06e-05 GGGTAAACAC TGAGTCA CTGTGTGTAA chr2:10014220-10014720 + 85 5.06e-05 TGCGTATGGG TGAGTCA GGTGGGCAG chr16:15590866-15591366 + 51 5.06e-05 cttgaaacag tgagtca gatcctgtta chr13:110965219-11096571 - 10 5.06e-05 GGGTGGAGAA TGAGTCA GGATGGAGT chr1:153566438-153566938 - 56 5.06e-05 GAACCTCGGG TGAGTCA CTTAGGGCTG chr1:41870087-41870587 + 44 5.06e-05 ccccctagta tgagtca cattcgactt chr1:236097023-236097523 - 13 5.06e-05 TGCTCCATTC TGAGTCA CCCCTGGCCG chr3:14452053-14452553 - 67 5.06e-05 AGCCAGGCTG TGAGTCA TTGGGACCAC chr16:4944709-4945209 + 58 5.06e-05 GGGTCTACGG TGAGTCA TGCTCTGCCT chr13:110870184-11087068 - 16 5.06e-05 TGACCAGCGC TGAGTCA GTCTAGGAGC chr21:34845654-34846154 + 45 5.06e-05 TAACACAGAA TGAGTCA AACAGTATTA chr1:228902971-228903471 + 57 5.06e-05 CCAATCCTCA TGAGTCA ACCAGAGAGC chr13:113493242-11349374 + 28 5.06e-05 AGCAGTTGAG TGAGTCA TTAAAATAAC chr6:29845315-29845815 - 40 5.06e-05 GTAATCAGAA TGAGTCA GGGTGGAGCA chr18:50239980-50240480 - 5 5.06e-05 GTAATCTGAA TGAGTCA GGGT chr9:135188499-135188999 + 36 5.06e-05 GCATGCCTAC TGAGTCA CGCCCTTGCC chr10:103896194-10389669 + 68 5.06e-05 AGTAAATAAA TGAGTCA CGTTACAACA chr1:73183529-73184029 - 78 5.06e-05 GTAATGGGAA TGAGTCA TGGTGGAGCA chrX:134718238-134718738 + 9 5.06e-05 GACTTCAG TGAGTCA CCGTTTTTAC chr5:1881187-1881687 + 28 5.06e-05 ATAGGAAGGA TGAGTCA GAGAGGGGCT chr9:131735349-131735849 + 40 5.06e-05 GATGGAGTAA TGAGTCA ATGAAGGGAT chr8:37142737-37143237 - 14 5.06e-05 CCATGATGCA TGAGTCA TTGAGTGGGA chr22:49970676-49971176 - 94 5.06e-05 . TGAGTCA CAGGAGGCGC chr22:40711447-40711947 + 56 5.06e-05 tacagagaca tgagtca tcgagaggct chr1:228861083-228861583 - 92 5.06e-05 GT TGAGTCA TCTATTTCTT chr1:234700128-234700628 - 72 5.06e-05 ATAATGCCTC TGAGTCA TCCATTAACC chr19:4575293-4575793 + 62 5.06e-05 CAAGTCCTGG TGAGTCA GGGCTCAGGA chr20:25237753-25238253 - 17 5.06e-05 AACACAAGGA TGAGTCA CCTACGACTT chr1:159924437-159924937 + 1 5.06e-05 . TGAGTCA CCCACCGCCC chr12:63419065-63419565 - 42 5.06e-05 GCAATCAGAA TGAGTCA GAGTGGAGCA chr1:227953574-227954074 + 6 5.06e-05 ACTCA TGAGTCA TCTGAAATGG chr6:3911802-3912302 + 80 5.06e-05 CAGGCACTAG TGAGTCA CTTTTTGAGG chr16:29943953-29944453 - 18 5.06e-05 AATAAACCTC TGAGTCA GCCTGGACTC chr19:41323502-41324002 + 22 5.06e-05 TCATGGGTCC TGAGTCA TCCCACACAC chr15:75721029-75721529 + 85 5.06e-05 CAACTCAGGC TGAGTCA AGTGTGAGA chr1:36386435-36386935 - 19 5.06e-05 AGGGCCCCAG TGAGTCA CTTGCCTGAT chr17:45320834-45321334 + 51 5.06e-05 AAGTGGCTGA TGAGTCA TCTGAATGTG chr18:48998085-48998585 - 7 5.06e-05 TCCAGGGCCC TGAGTCA CTACGG chr21:44279789-44280289 - 14 5.06e-05 TCTGAGTCAC TGAGTCA CTCCGGTTTC chr17:72465449-72465949 - 73 5.06e-05 GCACAATTTA TGAGTCA CCCCGAGCAG chr8:23074571-23075071 - 73 5.06e-05 TCTCCCCAGA TGAGTCA TTAACTGGGG chr20:3811635-3812135 + 34 5.06e-05 TGCCAGGCTC TGAGTCA GCGGGGCCTG chr6:52503860-52504360 + 81 5.06e-05 TATGTCACTG TGAGTCA TTCTTGGAGA chr2:10014774-10015274 + 14 5.06e-05 TGCGTATGGA TGAGTCA GGTGGACAGG chr11:36149639-36150139 - 34 5.06e-05 ATGAGGAACA TGAGTCA TGAGGAACAG chr17:39769870-39770370 - 46 5.06e-05 TCATACACAT TGAGTCA TCGTGTCTAC chr8:38528011-38528511 - 35 5.06e-05 GTGTCAGTTG TGAGTCA CCAATTGTGT chr16:3020700-3021200 + 77 5.06e-05 TGCCCAGGAG TGAGTCA CCCGCCGGCG chr1:230104645-230105145 + 3 5.06e-05 GC TGAGTCA CAGCTGACTT chr7:101138394-101138894 - 39 5.06e-05 AATGCGGCTG TGAGTCA CCCTGTAATT chr1:15800069-15800569 + 28 5.06e-05 GGGGATGCAG TGAGTCA CTGGGTGCAA chr1:214439422-214439922 + 83 5.06e-05 TATCATTATT TGAGTCA CACCTGGTAA chr1:5551499-5551999 + 58 5.06e-05 CTACAGTGAG TGAGTCA TAAAAAGCAG chr1:67700687-67701187 + 19 5.06e-05 ATAGTGAATA TGAGTCA CCACCATCTA chr10:77350593-77351093 - 84 5.06e-05 AGTCAACCAC TGAGTCA CCGGTGAGCA chr11:9759514-9760014 + 56 5.06e-05 CATGTGCAGC TGAGTCA CAACCACTTC chr9:1458445-1458945 + 29 5.06e-05 ACTTGGTGGC TGAGTCA TGAGGAAAAA chr1:156660080-156660580 + 39 5.06e-05 CTGGGGGCTG TGAGTCA GCGGAGGTTG chr20:57698179-57698679 - 53 5.06e-05 TCCTCGTTAT TGAGTCA TTTCAGATGC chr1:14929453-14929953 + 12 5.06e-05 GTGTTTGCTG TGAGTCA CTAAGGGCTG chr17:83089755-83090255 - 69 5.06e-05 TCGCCCTCTG TGAGTCA CGGCCCCACG chr20:4041741-4042241 - 70 5.06e-05 CTCCATGCTA TGAGTCA GAGCAACCAG chr21:43857410-43857910 - 17 5.06e-05 ATTACAGGCA TGAGTCA CTACACCCGA chr11:9565954-9566454 + 11 5.06e-05 GACTCACCAC TGAGTCA TCAAAACACA chr6:6678172-6678672 + 43 5.06e-05 atcacatatg tgagtca ctgacctaca chr19:44259667-44260167 + 73 5.06e-05 CTCTGGGAGG TGAGTCA GCGCGGAACC chr19:43798600-43799100 + 38 5.06e-05 GAGGGCGTCA TGAGTCA TGAGGTGGGC chr1:201713359-201713859 - 17 5.06e-05 AGGGAAATTC TGAGTCA CAGCAGAGCC chr15:74546038-74546538 + 56 5.06e-05 TACCGGCCGC TGAGTCA GCTCATAGCA chr1:228838378-228838878 - 36 5.06e-05 GCCAACAGCA TGAGTCA CTGACCCCTG chr21:43307000-43307500 + 31 5.06e-05 TGCAGGGCCA TGAGTCA CACCCAAGGT chr5:125485067-125485567 - 43 5.06e-05 GCCATTCGTG TGAGTCA CGGAGTGACT chr3:4741599-4742099 + 59 5.06e-05 AAGTCAGGAA TGAGTCA CTTCTGAGCG chr17:75124208-75124708 - 58 5.06e-05 AGATGAAGCC TGAGTCA CTGCCTGGCA chr1:41783139-41783639 - 27 5.06e-05 CCCCTCTCTT TGAGTCA GTGTGTGATT chr10:126199173-12619967 - 66 5.06e-05 ACAATATGGC TGAGTCA TGGGTAGTCG chr19:11018117-11018617 - 16 5.06e-05 TGGGGAGGGG TGAGTCA CCTGAGACCG chr22:46773775-46774275 - 44 5.06e-05 TCCTGGTGAG TGAGTCA GCTTTCTCTG chr1:227946203-227946703 + 26 5.06e-05 AAGGCCACGG TGAGTCA CCGCGGACCT chr1:223707103-223707603 - 57 5.06e-05 AGGATGGTGG TGAGTCA GAAACAGCTG chr8:22678252-22678752 - 11 5.06e-05 TTGGATGAGT TGAGTCA TTACCTCCAT chr3:194322630-194323130 + 48 5.06e-05 GATTAATGCC TGAGTCA CTCTGTCCGC chr17:4949582-4950082 + 72 5.06e-05 GCCGCGCGGC TGAGTCA CTGGCGGGCT chr6:125812676-125813176 - 10 5.06e-05 TGACATTTGA TGAGTCA TGCAGTGTA chr6:158040319-158040819 - 67 5.06e-05 CCTCCCTGAA TGAGTCA GTGGCCTTAT chr19:11094950-11095450 + 63 5.06e-05 GCACAAGAAA TGAGTCA TTTCCTCCTT chr6:47134654-47135154 - 6 5.06e-05 TACCTTGGTG TGAGTCA TTTCC chr14:104677696-10467819 - 22 5.06e-05 GCTGCGGTGC TGAGTCA CGCTCCGGAA chr11:64854878-64855378 + 46 5.06e-05 CCACGCAGGG TGAGTCA CCACATTCCC chr1:151988332-151988832 + 80 5.06e-05 GAATCTGGCA TGAGTCA TCTGAAAGGC chr16:324364-324864 - 67 1.01e-04 TAAGTGTGTC TGTGTCA TGTGCTGACG chr9:126791449-126791949 - 10 1.01e-04 TCAACTTGAG TGTGTCA TCTGTTTCC chr19:13051513-13052013 + 73 1.01e-04 GATACTAATC TGTGTCA ACAGGCCCCA chr16:2799746-2800246 + 36 1.01e-04 CCTAcagtca tgtgtca cttaatgacc chr15:70196560-70197060 - 37 1.01e-04 AAGATTGGTT TGTGTCA CAGGCAACGC chr1:155127111-155127611 - 1 1.01e-04 TTCTGGAGAT TGTGTCA chr22:43275465-43275965 - 57 1.01e-04 AACCTCGGTA TGTGTCA TCCTCTGCCT chr11:65421135-65421635 - 34 1.01e-04 CTGGTGACTG TGTGTCA TCTGACCTTC chr21:38907009-38907509 - 16 1.01e-04 CAGCACTGAG TGTGTCA CTCGGGCAGC chr20:50661148-50661648 - 75 1.01e-04 TAAAAAAGGA TGTGTCA CAAGGCTATG chr7:151727580-151728080 + 53 1.01e-04 CATTAGCTGA TGTGTCA TCTCTTCCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:3890048-3890548 5.1e-05 89_[-3]_4 chr8:630791-631291 5.1e-05 26_[-3]_67 chr19:40920964-40921464 5.1e-05 32_[+3]_61 chr2:10014220-10014720 5.1e-05 84_[+3]_9 chr16:15590866-15591366 5.1e-05 50_[+3]_43 chr13:110965219-11096571 5.1e-05 9_[-3]_84 chr1:153566438-153566938 5.1e-05 55_[-3]_38 chr1:41870087-41870587 5.1e-05 43_[+3]_50 chr1:236097023-236097523 5.1e-05 12_[-3]_81 chr3:14452053-14452553 5.1e-05 66_[-3]_27 chr16:4944709-4945209 5.1e-05 57_[+3]_36 chr13:110870184-11087068 5.1e-05 15_[-3]_78 chr21:34845654-34846154 5.1e-05 44_[+3]_49 chr1:228902971-228903471 5.1e-05 56_[+3]_37 chr13:113493242-11349374 5.1e-05 27_[+3]_66 chr6:29845315-29845815 5.1e-05 39_[-3]_54 chr18:50239980-50240480 5.1e-05 4_[-3]_89 chr9:135188499-135188999 5.1e-05 35_[+3]_58 chr10:103896194-10389669 5.1e-05 67_[+3]_26 chr1:73183529-73184029 5.1e-05 77_[-3]_16 chrX:134718238-134718738 5.1e-05 8_[+3]_85 chr5:1881187-1881687 5.1e-05 27_[+3]_66 chr9:131735349-131735849 5.1e-05 39_[+3]_54 chr8:37142737-37143237 5.1e-05 13_[-3]_80 chr22:49970676-49971176 5.1e-05 93_[-3] chr22:40711447-40711947 5.1e-05 55_[+3]_38 chr1:228861083-228861583 5.1e-05 91_[-3]_2 chr1:234700128-234700628 5.1e-05 71_[-3]_22 chr19:4575293-4575793 5.1e-05 61_[+3]_32 chr20:25237753-25238253 5.1e-05 16_[-3]_77 chr1:159924437-159924937 5.1e-05 [+3]_93 chr12:63419065-63419565 5.1e-05 41_[-3]_52 chr1:227953574-227954074 5.1e-05 5_[+3]_88 chr6:3911802-3912302 5.1e-05 79_[+3]_14 chr16:29943953-29944453 5.1e-05 17_[-3]_76 chr19:41323502-41324002 5.1e-05 21_[+3]_72 chr15:75721029-75721529 5.1e-05 84_[+3]_9 chr1:36386435-36386935 5.1e-05 18_[-3]_75 chr17:45320834-45321334 5.1e-05 50_[+3]_43 chr18:48998085-48998585 5.1e-05 6_[-3]_87 chr21:44279789-44280289 5.1e-05 13_[-3]_80 chr17:72465449-72465949 5.1e-05 72_[-3]_21 chr8:23074571-23075071 5.1e-05 72_[-3]_21 chr20:3811635-3812135 5.1e-05 33_[+3]_60 chr6:52503860-52504360 5.1e-05 80_[+3]_13 chr2:10014774-10015274 5.1e-05 13_[+3]_80 chr11:36149639-36150139 5.1e-05 33_[-3]_60 chr17:39769870-39770370 5.1e-05 45_[-3]_48 chr8:38528011-38528511 5.1e-05 34_[-3]_59 chr16:3020700-3021200 5.1e-05 76_[+3]_17 chr1:230104645-230105145 5.1e-05 2_[+3]_91 chr7:101138394-101138894 5.1e-05 38_[-3]_55 chr1:15800069-15800569 5.1e-05 27_[+3]_66 chr1:214439422-214439922 5.1e-05 82_[+3]_11 chr1:5551499-5551999 5.1e-05 57_[+3]_36 chr1:67700687-67701187 5.1e-05 18_[+3]_75 chr10:77350593-77351093 5.1e-05 83_[-3]_10 chr11:9759514-9760014 5.1e-05 55_[+3]_38 chr9:1458445-1458945 5.1e-05 28_[+3]_65 chr1:156660080-156660580 5.1e-05 38_[+3]_55 chr20:57698179-57698679 5.1e-05 52_[-3]_41 chr1:14929453-14929953 5.1e-05 11_[+3]_82 chr17:83089755-83090255 5.1e-05 68_[-3]_25 chr20:4041741-4042241 5.1e-05 69_[-3]_24 chr21:43857410-43857910 5.1e-05 16_[-3]_77 chr11:9565954-9566454 5.1e-05 10_[+3]_83 chr6:6678172-6678672 5.1e-05 42_[+3]_51 chr19:44259667-44260167 5.1e-05 72_[+3]_21 chr19:43798600-43799100 5.1e-05 37_[+3]_56 chr1:201713359-201713859 5.1e-05 16_[-3]_77 chr15:74546038-74546538 5.1e-05 55_[+3]_38 chr1:228838378-228838878 5.1e-05 35_[-3]_58 chr21:43307000-43307500 5.1e-05 30_[+3]_63 chr5:125485067-125485567 5.1e-05 42_[-3]_51 chr3:4741599-4742099 5.1e-05 58_[+3]_35 chr17:75124208-75124708 5.1e-05 57_[-3]_36 chr1:41783139-41783639 5.1e-05 26_[-3]_67 chr10:126199173-12619967 5.1e-05 65_[-3]_28 chr19:11018117-11018617 5.1e-05 15_[-3]_78 chr22:46773775-46774275 5.1e-05 43_[-3]_50 chr1:227946203-227946703 5.1e-05 25_[+3]_68 chr1:223707103-223707603 5.1e-05 56_[-3]_37 chr8:22678252-22678752 5.1e-05 10_[-3]_83 chr3:194322630-194323130 5.1e-05 47_[+3]_46 chr17:4949582-4950082 5.1e-05 71_[+3]_22 chr6:125812676-125813176 5.1e-05 9_[-3]_84 chr6:158040319-158040819 5.1e-05 66_[-3]_27 chr19:11094950-11095450 5.1e-05 62_[+3]_31 chr6:47134654-47135154 5.1e-05 5_[-3]_88 chr14:104677696-10467819 5.1e-05 21_[-3]_72 chr11:64854878-64855378 5.1e-05 45_[+3]_48 chr1:151988332-151988832 5.1e-05 79_[+3]_14 chr16:324364-324864 0.0001 66_[-3]_27 chr9:126791449-126791949 0.0001 9_[-3]_84 chr19:13051513-13052013 0.0001 72_[+3]_21 chr16:2799746-2800246 0.0001 35_[+3]_58 chr15:70196560-70197060 0.0001 36_[-3]_57 chr1:155127111-155127611 0.0001 [-3]_93 chr22:43275465-43275965 0.0001 56_[-3]_37 chr11:65421135-65421635 0.0001 33_[-3]_60 chr21:38907009-38907509 0.0001 15_[-3]_78 chr20:50661148-50661648 0.0001 74_[-3]_19 chr7:151727580-151728080 0.0001 52_[+3]_41 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGAGTCA width=7 seqs=103 chr17:3890048-3890548 ( 90) TGAGTCA 1 chr8:630791-631291 ( 27) TGAGTCA 1 chr19:40920964-40921464 ( 33) TGAGTCA 1 chr2:10014220-10014720 ( 85) TGAGTCA 1 chr16:15590866-15591366 ( 51) TGAGTCA 1 chr13:110965219-11096571 ( 10) TGAGTCA 1 chr1:153566438-153566938 ( 56) TGAGTCA 1 chr1:41870087-41870587 ( 44) TGAGTCA 1 chr1:236097023-236097523 ( 13) TGAGTCA 1 chr3:14452053-14452553 ( 67) TGAGTCA 1 chr16:4944709-4945209 ( 58) TGAGTCA 1 chr13:110870184-11087068 ( 16) TGAGTCA 1 chr21:34845654-34846154 ( 45) TGAGTCA 1 chr1:228902971-228903471 ( 57) TGAGTCA 1 chr13:113493242-11349374 ( 28) TGAGTCA 1 chr6:29845315-29845815 ( 40) TGAGTCA 1 chr18:50239980-50240480 ( 5) TGAGTCA 1 chr9:135188499-135188999 ( 36) TGAGTCA 1 chr10:103896194-10389669 ( 68) TGAGTCA 1 chr1:73183529-73184029 ( 78) TGAGTCA 1 chrX:134718238-134718738 ( 9) TGAGTCA 1 chr5:1881187-1881687 ( 28) TGAGTCA 1 chr9:131735349-131735849 ( 40) TGAGTCA 1 chr8:37142737-37143237 ( 14) TGAGTCA 1 chr22:49970676-49971176 ( 94) TGAGTCA 1 chr22:40711447-40711947 ( 56) TGAGTCA 1 chr1:228861083-228861583 ( 92) TGAGTCA 1 chr1:234700128-234700628 ( 72) TGAGTCA 1 chr19:4575293-4575793 ( 62) TGAGTCA 1 chr20:25237753-25238253 ( 17) TGAGTCA 1 chr1:159924437-159924937 ( 1) TGAGTCA 1 chr12:63419065-63419565 ( 42) TGAGTCA 1 chr1:227953574-227954074 ( 6) TGAGTCA 1 chr6:3911802-3912302 ( 80) TGAGTCA 1 chr16:29943953-29944453 ( 18) TGAGTCA 1 chr19:41323502-41324002 ( 22) TGAGTCA 1 chr15:75721029-75721529 ( 85) TGAGTCA 1 chr1:36386435-36386935 ( 19) TGAGTCA 1 chr17:45320834-45321334 ( 51) TGAGTCA 1 chr18:48998085-48998585 ( 7) TGAGTCA 1 chr21:44279789-44280289 ( 14) TGAGTCA 1 chr17:72465449-72465949 ( 73) TGAGTCA 1 chr8:23074571-23075071 ( 73) TGAGTCA 1 chr20:3811635-3812135 ( 34) TGAGTCA 1 chr6:52503860-52504360 ( 81) TGAGTCA 1 chr2:10014774-10015274 ( 14) TGAGTCA 1 chr11:36149639-36150139 ( 34) TGAGTCA 1 chr17:39769870-39770370 ( 46) TGAGTCA 1 chr8:38528011-38528511 ( 35) TGAGTCA 1 chr16:3020700-3021200 ( 77) TGAGTCA 1 chr1:230104645-230105145 ( 3) TGAGTCA 1 chr7:101138394-101138894 ( 39) TGAGTCA 1 chr1:15800069-15800569 ( 28) TGAGTCA 1 chr1:214439422-214439922 ( 83) TGAGTCA 1 chr1:5551499-5551999 ( 58) TGAGTCA 1 chr1:67700687-67701187 ( 19) TGAGTCA 1 chr10:77350593-77351093 ( 84) TGAGTCA 1 chr11:9759514-9760014 ( 56) TGAGTCA 1 chr9:1458445-1458945 ( 29) TGAGTCA 1 chr1:156660080-156660580 ( 39) TGAGTCA 1 chr20:57698179-57698679 ( 53) TGAGTCA 1 chr1:14929453-14929953 ( 12) TGAGTCA 1 chr17:83089755-83090255 ( 69) TGAGTCA 1 chr20:4041741-4042241 ( 70) TGAGTCA 1 chr21:43857410-43857910 ( 17) TGAGTCA 1 chr11:9565954-9566454 ( 11) TGAGTCA 1 chr6:6678172-6678672 ( 43) TGAGTCA 1 chr19:44259667-44260167 ( 73) TGAGTCA 1 chr19:43798600-43799100 ( 38) TGAGTCA 1 chr1:201713359-201713859 ( 17) TGAGTCA 1 chr15:74546038-74546538 ( 56) TGAGTCA 1 chr1:228838378-228838878 ( 36) TGAGTCA 1 chr21:43307000-43307500 ( 31) TGAGTCA 1 chr5:125485067-125485567 ( 43) TGAGTCA 1 chr3:4741599-4742099 ( 59) TGAGTCA 1 chr17:75124208-75124708 ( 58) TGAGTCA 1 chr1:41783139-41783639 ( 27) TGAGTCA 1 chr10:126199173-12619967 ( 66) TGAGTCA 1 chr19:11018117-11018617 ( 16) TGAGTCA 1 chr22:46773775-46774275 ( 44) TGAGTCA 1 chr1:227946203-227946703 ( 26) TGAGTCA 1 chr1:223707103-223707603 ( 57) TGAGTCA 1 chr8:22678252-22678752 ( 11) TGAGTCA 1 chr3:194322630-194323130 ( 48) TGAGTCA 1 chr17:4949582-4950082 ( 72) TGAGTCA 1 chr6:125812676-125813176 ( 10) TGAGTCA 1 chr6:158040319-158040819 ( 67) TGAGTCA 1 chr19:11094950-11095450 ( 63) TGAGTCA 1 chr6:47134654-47135154 ( 6) TGAGTCA 1 chr14:104677696-10467819 ( 22) TGAGTCA 1 chr11:64854878-64855378 ( 46) TGAGTCA 1 chr1:151988332-151988832 ( 80) TGAGTCA 1 chr16:324364-324864 ( 67) TGTGTCA 1 chr9:126791449-126791949 ( 10) TGTGTCA 1 chr19:13051513-13052013 ( 73) TGTGTCA 1 chr16:2799746-2800246 ( 36) TGTGTCA 1 chr15:70196560-70197060 ( 37) TGTGTCA 1 chr1:155127111-155127611 ( 1) TGTGTCA 1 chr22:43275465-43275965 ( 57) TGTGTCA 1 chr11:65421135-65421635 ( 34) TGTGTCA 1 chr21:38907009-38907509 ( 16) TGTGTCA 1 chr20:50661148-50661648 ( 75) TGTGTCA 1 chr7:151727580-151728080 ( 53) TGTGTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 7 n= 56400 bayes= 10.2524 E= 8.5e-058 -1333 -1333 -1333 220 -1333 -1333 183 -1333 203 -1333 -1333 -103 -1333 -1333 183 -1333 -1333 -1333 -1333 220 -1333 183 -1333 -1333 220 -1333 -1333 -1333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 7 nsites= 103 E= 8.5e-058 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.893204 0.000000 0.000000 0.106796 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGTCA MEME-3 regular expression -------------------------------------------------------------------------------- TGAGTCA -------------------------------------------------------------------------------- Time 1489.60 secs. ******************************************************************************** ******************************************************************************** MOTIF ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 width = 43 sites = 7 llr = 301 E-value = 9.2e-032 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 Description -------------------------------------------------------------------------------- Simplified A 91:7:1:1::::a::::19:::a::::191:9:::1:::17:: pos.-specific C :16:a9::93aa:aa9::19:7::3a631:3199:1a3a717a probability G 1::1:::7:::::::::7:::::::::6::1::::7:::::1: matrix T :741::a117:::::1a1:1a3:a7:4::96:11a::7:111: bits 2.2 * * * * ** * 2.0 * * * * ** * 1.8 * * ***** * * ** * * * * * 1.5 * * * ***** * * * ** * ** * * * * * Relative 1.3 * *** ********* *** **** ** **** *** * Entropy 1.1 ******* ********* ********* ** **** *** * * (62.1 bits) 0.9 *************************** ** **** ***** * 0.7 *************************** *************** 0.4 ******************************************* 0.2 ******************************************* 0.0 ------------------------------------------- Multilevel ATCACCTGCTCCACCCTGACTCATTCCGATTACCTGCTCCACC consensus T C T C TC C C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------------------- chr1:73183529-73184029 + 34 9.22e-25 actcattccc attacctgctccaccctgacttattcccattacctgctccacc atgactcatt chr15:25758486-25758986 + 49 1.14e-22 cctcattccg accacctgctccaccctaactcattccgatcacctgctccacc ctAACTCAt chr18:50239980-50240480 + 45 3.10e-22 actcattctg atcacctgccccaccctgactcattcTGATCACCTACCCCACC CTGATTCAtt chr6:29845315-29845815 + 52 7.21e-21 actcattctg attacctgctccaccctgattcatcctgattacttgccccagc ctgact chr12:63419065-63419565 + 54 3.79e-20 actcattctg attgcctactccaccctgactcattccaattacctgctcattc tccg chr13:110965219-11096571 + 56 8.96e-20 actccaccct gactcattttccaccctgactcattccgattacctgctccacc ct chr1:44791469-44791969 + 56 3.72e-16 CAGCCCATAA ATCACCTGCCCCACCTTTCCTTATCCTCCAGCTCTCCTCTCCC TC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:73183529-73184029 9.2e-25 33_[+4]_24 chr15:25758486-25758986 1.1e-22 48_[+4]_9 chr18:50239980-50240480 3.1e-22 44_[+4]_13 chr6:29845315-29845815 7.2e-21 51_[+4]_6 chr12:63419065-63419565 3.8e-20 53_[+4]_4 chr13:110965219-11096571 9e-20 55_[+4]_2 chr1:44791469-44791969 3.7e-16 55_[+4]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC width=43 seqs=7 chr1:73183529-73184029 ( 34) ATTACCTGCTCCACCCTGACTTATTCCCATTACCTGCTCCACC 1 chr15:25758486-25758986 ( 49) ACCACCTGCTCCACCCTAACTCATTCCGATCACCTGCTCCACC 1 chr18:50239980-50240480 ( 45) ATCACCTGCCCCACCCTGACTCATTCTGATCACCTACCCCACC 1 chr6:29845315-29845815 ( 52) ATTACCTGCTCCACCCTGATTCATCCTGATTACTTGCCCCAGC 1 chr12:63419065-63419565 ( 54) ATTGCCTACTCCACCCTGACTCATTCCAATTACCTGCTCATTC 1 chr13:110965219-11096571 ( 56) GACTCATTTTCCACCCTGACTCATTCCGATTACCTGCTCCACC 1 chr1:44791469-44791969 ( 56) ATCACCTGCCCCACCTTTCCTTATCCTCCAGCTCTCCTCTCCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 43 n= 34800 bayes= 12.123 E= 9.2e-032 197 -945 -98 -945 -61 -98 -945 171 -945 102 -945 97 171 -945 -98 -61 -945 182 -945 -945 -61 160 -945 -945 -945 -945 -945 220 -61 -945 134 -61 -945 160 -945 -61 -945 2 -945 171 -945 182 -945 -945 -945 182 -945 -945 220 -945 -945 -945 -945 182 -945 -945 -945 182 -945 -945 -945 160 -945 -61 -945 -945 -945 220 -61 -945 134 -61 197 -98 -945 -945 -945 160 -945 -61 -945 -945 -945 220 -945 134 -945 39 220 -945 -945 -945 -945 -945 -945 220 -945 2 -945 171 -945 182 -945 -945 -945 102 -945 97 -61 2 102 -945 197 -98 -945 -945 -61 -945 -945 197 -945 2 -98 139 197 -98 -945 -945 -945 160 -945 -61 -945 160 -945 -61 -945 -945 -945 220 -61 -98 134 -945 -945 182 -945 -945 -945 2 -945 171 -945 182 -945 -945 -61 134 -945 -61 171 -98 -945 -61 -945 134 -98 -61 -945 182 -945 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 43 nsites= 7 E= 9.2e-032 0.857143 0.000000 0.142857 0.000000 0.142857 0.142857 0.000000 0.714286 0.000000 0.571429 0.000000 0.428571 0.714286 0.000000 0.142857 0.142857 0.000000 1.000000 0.000000 0.000000 0.142857 0.857143 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.142857 0.000000 0.714286 0.142857 0.000000 0.857143 0.000000 0.142857 0.000000 0.285714 0.000000 0.714286 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.000000 0.000000 1.000000 0.142857 0.000000 0.714286 0.142857 0.857143 0.142857 0.000000 0.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.000000 0.000000 1.000000 0.000000 0.714286 0.000000 0.285714 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.285714 0.000000 0.714286 0.000000 1.000000 0.000000 0.000000 0.000000 0.571429 0.000000 0.428571 0.142857 0.285714 0.571429 0.000000 0.857143 0.142857 0.000000 0.000000 0.142857 0.000000 0.000000 0.857143 0.000000 0.285714 0.142857 0.571429 0.857143 0.142857 0.000000 0.000000 0.000000 0.857143 0.000000 0.142857 0.000000 0.857143 0.000000 0.142857 0.000000 0.000000 0.000000 1.000000 0.142857 0.142857 0.714286 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.285714 0.000000 0.714286 0.000000 1.000000 0.000000 0.000000 0.142857 0.714286 0.000000 0.142857 0.714286 0.142857 0.000000 0.142857 0.000000 0.714286 0.142857 0.142857 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATYACCTGCTCCACCCTGACTCATTCYSATYACCTGCTCCACC MEME-4 regular expression -------------------------------------------------------------------------------- AT[CT]ACCTGC[TC]CCACCCTGACT[CT]AT[TC]C[CT][GC]AT[TC]ACCTGC[TC]CCACC -------------------------------------------------------------------------------- Time 1935.40 secs. ******************************************************************************** ******************************************************************************** MOTIF VATGAYSTCACC MEME-5 width = 12 sites = 85 llr = 812 E-value = 9.3e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 Description -------------------------------------------------------------------------------- Simplified A 37::a12:1a:2 pos.-specific C 32:::53:9:75 probability G 41:8:25:::1: matrix T ::a1:3:a::22 bits 2.2 * * 2.0 * * * * 1.8 * * * * 1.5 * * *** Relative 1.3 * * *** Entropy 1.1 **** *** (13.8 bits) 0.9 **** *** 0.7 **** **** 0.4 **** **** 0.2 ************ 0.0 ------------ Multilevel GATGACGTCACC consensus C TC TT sequence A A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr12:132445991-13244649 + 20 6.98e-08 CGCTCCTGTA GATGACGTCACC ACAGTAAGAC chr19:996297-996797 - 52 6.98e-08 GGGTCTGAAC GATGACGTCACC ACTGTTTCCA chr8:22109466-22109966 - 29 6.98e-08 CTGCAGGAAA GATGACGTCACC GTCGGAGCTC chr10:124323112-12432361 + 45 1.24e-07 GATGTCATTT AATGACGTCACC CTTCCACTCG chr19:35612474-35612974 + 29 5.21e-07 CCCGGCAACC GATGACGTCACT GTTGGCGCGC chr7:98418869-98419369 - 26 5.21e-07 TGTATTTGCT GATGACGTCACA TCCGTCCTGG chr8:22178741-22179241 - 10 6.59e-07 TGGGGGGCAG AATGACCTCACC ACCCTTCCT chr19:1021413-1021913 + 68 9.74e-07 CGGATCCTGC CATGACGTCACA GGGCCAGTAA chr17:78558298-78558798 + 14 1.19e-06 CTCATGGGTG GATGACATCACC CTCATGGGTG chr10:94673534-94674034 + 1 1.19e-06 . gatgacatcacc ttggcccagg chr17:51046593-51047093 - 24 1.41e-06 GGGAGAACGG AATGACGTCATC GCTTGGGAGC chr1:3992028-3992528 - 81 1.78e-06 CACCTCTC CATGACATCACC CCTCCATGAC chr17:74514127-74514627 - 44 1.78e-06 TCACCCATCA CATGACATCACC CATCACATGA chr1:1000656-1001156 - 60 1.78e-06 ACACGGGCCA CATGACGTCATC CCAGCAGGCT chr10:77350593-77351093 + 4 1.78e-06 TGT GATGACCTCACA ATCATGCCTG chr6:108558306-108558806 - 44 1.78e-06 CGTACAAACA GATGATGTCATC GTATCCACAC chr6:169395998-169396498 + 25 1.98e-06 AGGGACCGAA AATGACCTCACT CTGCAGACAA chr1:68217014-68217514 - 55 2.38e-06 GTTAACACCA CATGAGGTCACC AGGCTTCAAG chr8:144456684-144457184 + 17 2.71e-06 ACATCACAGA GATGACATCACA CTGGCATCAT chr15:70494066-70494566 - 85 2.71e-06 TAGT GATGACCTCATC CCGGGTTGTC chr19:35628752-35629252 - 58 3.64e-06 GGCGCTGGCG CATGACGTCATA CATTCGGGCG chr1:156660080-156660580 + 60 3.64e-06 AGGTTGAGAG GATGAGGTCACT CAGAGAACTG chr7:158097519-158098019 + 57 4.08e-06 AATGGTCTCT AATGATGTCATA AGAAATAATG chr17:21359020-21359520 + 23 4.76e-06 ccatttccta gatgaagtcact TGTTCCAGGT chr7:116218161-116218661 - 42 4.76e-06 TTCAATGAAA CATGATATCACT TTATCATCAA chr20:3173059-3173559 + 32 5.33e-06 GCGAAGCATC CATGACATCATC CGCCTCCTCT chr1:233112858-233113358 - 61 5.33e-06 GTGATGACAA GCTGATGTCACC CAACTGGCCA chr19:43572061-43572561 + 69 5.80e-06 cttgtgcaga cattatgtcacc gaattttcac chr1:229221162-229221662 - 5 6.55e-06 AAGGTAAATA GATGAAGTCATC CAGT chr7:157880964-157881464 - 17 6.55e-06 CACATACCCT CATGACCTCATT TTACCGTAAT chr5:17305875-17306375 + 47 8.29e-06 TGCTTCAGGC AATGATGTCAGC AGTTGCGTGT chr1:16159046-16159546 - 80 8.29e-06 ATTAGGGCT GATTATGTCACT ATAAATACCG chr16:73070486-73070986 - 12 8.29e-06 AGAGAGAGAC AATGATGTCAGC ATTTCCTTCT chr7:151727580-151728080 + 29 8.29e-06 GCTGTTCATT GATGAACTCACT AGCATTAGCT chr10:5548771-5549271 + 75 9.55e-06 TCTATCTCAG GGTGACGTCACC TCATACACAG chr1:17597003-17597503 - 47 9.55e-06 AGTAAGAGGC AATTATCTCACC CTTATCTGAG chr12:113245733-11324623 - 89 9.55e-06 . GCTGATGTCACA GGGCCCAGAC chr6:6678172-6678672 + 27 1.07e-05 gggagagtga aatgagatcaca tatgtgagtc chr22:37905058-37905558 - 8 1.21e-05 CTGCAGAGGT GGTGATGTCACC CTGACCC chr1:201713359-201713859 - 56 1.21e-05 GAGCTGACAG CATGAGCTCATC TGGGCAGTCC chr22:32539579-32540079 - 81 1.21e-05 CCTTCAGC CATGATATCATT TCCCTCCTCT chr1:175841755-175842255 + 27 1.36e-05 TACGTTAGAG GCTGAGGTCACC ATGGAGGTGT chr15:68623304-68623804 - 20 1.36e-05 GGCGGGAGAG GCTGACCTCACT CACTTCTGGC chr8:37359498-37359998 - 28 1.36e-05 ACTCCAGCCC GCTGAGGTCACC TTCCTGGCCT chr10:103896194-10389669 - 28 1.49e-05 CCCACCAGGG AATGATCTCAGC TTAAATGTCC chr3:138833396-138833896 + 26 1.67e-05 ATTTAATTAT CATGACTTCACC AGACAGTCAC chr3:9731327-9731827 - 41 1.83e-05 GTTTCTGGAG ACTGAAGTCACC GTACTCGGGA chr3:14452053-14452553 + 6 1.83e-05 gaggc agtgacctcacc tctccacgcc chr16:3020700-3021200 - 16 1.83e-05 ATAGCTGGGC ACTGAAGTCACC GGATGGAAGG chr13:112213422-11221392 + 81 2.03e-05 acctgccaac aatgacctcagt ccTGCCGG chr10:129440217-12944071 - 78 2.03e-05 GGCCCAATCG GATGAACTCATA GTGCATGGCA chr18:48998085-48998585 + 24 2.03e-05 GGGCCCTGGA CATGATGTAACA CCCCTGGCTC chr1:223992386-223992886 - 56 2.03e-05 GCGCGCCTTC CGTGACGTCACA AGGGCGGGTC chr15:75104738-75105238 - 64 2.28e-05 GCTTCCTGGG CATGACCTCAGA GTCCAGACAG chr1:175470966-175471466 + 20 2.28e-05 CGGGCTGAGT AATGAACTCATT TATGTCCTTC chr17:60173295-60173795 - 39 2.50e-05 AGTGCTGACT GATGACATCAGA CACTAGGCTA chr16:1971754-1972254 - 87 2.99e-05 GC GATGGCGTCACC GCGCGCGACC chr13:41696486-41696986 - 13 2.99e-05 GTTAAATGCT GATGACATAACA TGTAAGAGAT chr7:151079992-151080492 + 11 3.24e-05 gcagggctgg cattacctcatt tcaccggtgg chr17:3888450-3888950 - 56 3.80e-05 GGATGGGGAG CCTGACGTCAGC CCTCGCGGCC chr19:40602280-40602780 - 44 3.80e-05 TCAGGCGGGA GATGAGCTCACG CCGGCCGGGC chr19:10416563-10417063 + 5 4.17e-05 GTCC GCTGACGTCACG CCCCAGGAGA chr6:41767104-41767604 + 37 4.50e-05 gcctgaggca agttacgtcacc tcttggcctg chr17:79020161-79020661 + 49 4.89e-05 GCAGACTTTA ACTGAGATCACA TTGCTTTTTC chr10:87845976-87846476 + 24 5.32e-05 acagaaacgt cattatgtcacg caagactAGA chr7:44039050-44039550 - 33 5.32e-05 CCCCTAGACC CATGGCCTCACC TCCCATCATC chr1:27321855-27322355 - 81 5.32e-05 CTCGTCCC CATGGCGTCACT TCCCGGAGAT chr1:228838378-228838878 - 18 5.32e-05 GTCACTGACC CCTGAGGTCATT CTGGCTCTTT chr10:75379161-75379661 + 27 5.32e-05 TCGGATGGAT AATAATGTCATT TGCTTGATGC chr10:50067611-50068111 - 71 5.70e-05 CCTCACGTGA CCTGATGTCACG TGACAGAACC chr15:70089037-70089537 + 47 5.70e-05 ccacattagc acttacctcact gcattgcaat chr1:31387527-31388027 + 63 6.15e-05 CATCCACACG GACGACCTCACC CACATCCCCA chr10:93209024-93209524 + 25 6.15e-05 ATGATCTGTT TATGATCTCACT GCTTATGATC chr2:109213990-109214490 + 57 6.15e-05 AACCACAAGA GATAAGATCACC CAAAGGGAGT chr1:227953574-227954074 + 79 6.60e-05 CCGTGGGCAG AGTGAGCTCACA GGCTGCGCCg chr11:9759514-9760014 + 10 6.60e-05 AAGCAAAGC CATAAAGTCACA GCTGGCCTGT chr9:126791449-126791949 - 47 7.63e-05 TACCTTTGTA AATAATCTCATT GCTAAACTCT chr10:22552772-22553272 - 55 7.63e-05 TTCCCTGTCA CATGAGGTAATT CTGCTGGGGT chr19:2529435-2529935 - 14 8.76e-05 ATGACACGGA AATGATCTAAGC ATGACTGGTC chr1:229148078-229148578 + 61 8.76e-05 GGTCCTGGGC CCTTATCTCATC AGCACACAAG chr1:47690362-47690862 - 25 1.13e-04 ATTCCCAGCA AATTATCTAATC CACATGTTGT chr10:3314556-3315056 + 52 1.28e-04 GGAAGGGGAG GGTGACTTCACA GAGTGAGGGA chr1:9802982-9803482 + 58 1.28e-04 GGGAGGAAAG GATTAGATAACC TCTCAAGGGG chr5:142215852-142216352 + 68 1.28e-04 TCCCTGCAAA GCTTATGTAACC GTAAGAGGAT chr17:19507972-19508472 - 6 1.35e-04 ACCATTGCGC CACGAGGTCACA CCAAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:132445991-13244649 7e-08 19_[+5]_69 chr19:996297-996797 7e-08 51_[-5]_37 chr8:22109466-22109966 7e-08 28_[-5]_60 chr10:124323112-12432361 1.2e-07 44_[+5]_44 chr19:35612474-35612974 5.2e-07 28_[+5]_60 chr7:98418869-98419369 5.2e-07 25_[-5]_63 chr8:22178741-22179241 6.6e-07 9_[-5]_79 chr19:1021413-1021913 9.7e-07 67_[+5]_21 chr17:78558298-78558798 1.2e-06 13_[+5]_75 chr10:94673534-94674034 1.2e-06 [+5]_88 chr17:51046593-51047093 1.4e-06 23_[-5]_65 chr1:3992028-3992528 1.8e-06 80_[-5]_8 chr17:74514127-74514627 1.8e-06 43_[-5]_45 chr1:1000656-1001156 1.8e-06 59_[-5]_29 chr10:77350593-77351093 1.8e-06 3_[+5]_85 chr6:108558306-108558806 1.8e-06 43_[-5]_45 chr6:169395998-169396498 2e-06 24_[+5]_64 chr1:68217014-68217514 2.4e-06 54_[-5]_34 chr8:144456684-144457184 2.7e-06 16_[+5]_72 chr15:70494066-70494566 2.7e-06 84_[-5]_4 chr19:35628752-35629252 3.6e-06 57_[-5]_31 chr1:156660080-156660580 3.6e-06 59_[+5]_29 chr7:158097519-158098019 4.1e-06 56_[+5]_32 chr17:21359020-21359520 4.8e-06 22_[+5]_66 chr7:116218161-116218661 4.8e-06 41_[-5]_47 chr20:3173059-3173559 5.3e-06 31_[+5]_57 chr1:233112858-233113358 5.3e-06 60_[-5]_28 chr19:43572061-43572561 5.8e-06 68_[+5]_20 chr1:229221162-229221662 6.5e-06 4_[-5]_84 chr7:157880964-157881464 6.5e-06 16_[-5]_72 chr5:17305875-17306375 8.3e-06 46_[+5]_42 chr1:16159046-16159546 8.3e-06 79_[-5]_9 chr16:73070486-73070986 8.3e-06 11_[-5]_77 chr7:151727580-151728080 8.3e-06 28_[+5]_60 chr10:5548771-5549271 9.6e-06 74_[+5]_14 chr1:17597003-17597503 9.6e-06 46_[-5]_42 chr12:113245733-11324623 9.6e-06 88_[-5] chr6:6678172-6678672 1.1e-05 26_[+5]_62 chr22:37905058-37905558 1.2e-05 7_[-5]_81 chr1:201713359-201713859 1.2e-05 55_[-5]_33 chr22:32539579-32540079 1.2e-05 80_[-5]_8 chr1:175841755-175842255 1.4e-05 26_[+5]_62 chr15:68623304-68623804 1.4e-05 19_[-5]_69 chr8:37359498-37359998 1.4e-05 27_[-5]_61 chr10:103896194-10389669 1.5e-05 27_[-5]_61 chr3:138833396-138833896 1.7e-05 25_[+5]_63 chr3:9731327-9731827 1.8e-05 40_[-5]_48 chr3:14452053-14452553 1.8e-05 5_[+5]_83 chr16:3020700-3021200 1.8e-05 15_[-5]_73 chr13:112213422-11221392 2e-05 80_[+5]_8 chr10:129440217-12944071 2e-05 77_[-5]_11 chr18:48998085-48998585 2e-05 23_[+5]_65 chr1:223992386-223992886 2e-05 55_[-5]_33 chr15:75104738-75105238 2.3e-05 63_[-5]_25 chr1:175470966-175471466 2.3e-05 19_[+5]_69 chr17:60173295-60173795 2.5e-05 38_[-5]_50 chr16:1971754-1972254 3e-05 86_[-5]_2 chr13:41696486-41696986 3e-05 12_[-5]_76 chr7:151079992-151080492 3.2e-05 10_[+5]_78 chr17:3888450-3888950 3.8e-05 55_[-5]_33 chr19:40602280-40602780 3.8e-05 43_[-5]_45 chr19:10416563-10417063 4.2e-05 4_[+5]_84 chr6:41767104-41767604 4.5e-05 36_[+5]_52 chr17:79020161-79020661 4.9e-05 48_[+5]_40 chr10:87845976-87846476 5.3e-05 23_[+5]_65 chr7:44039050-44039550 5.3e-05 32_[-5]_56 chr1:27321855-27322355 5.3e-05 80_[-5]_8 chr1:228838378-228838878 5.3e-05 17_[-5]_71 chr10:75379161-75379661 5.3e-05 26_[+5]_62 chr10:50067611-50068111 5.7e-05 70_[-5]_18 chr15:70089037-70089537 5.7e-05 46_[+5]_42 chr1:31387527-31388027 6.2e-05 62_[+5]_26 chr10:93209024-93209524 6.2e-05 24_[+5]_64 chr2:109213990-109214490 6.2e-05 56_[+5]_32 chr1:227953574-227954074 6.6e-05 78_[+5]_10 chr11:9759514-9760014 6.6e-05 9_[+5]_79 chr9:126791449-126791949 7.6e-05 46_[-5]_42 chr10:22552772-22553272 7.6e-05 54_[-5]_34 chr19:2529435-2529935 8.8e-05 13_[-5]_75 chr1:229148078-229148578 8.8e-05 60_[+5]_28 chr1:47690362-47690862 0.00011 24_[-5]_64 chr10:3314556-3315056 0.00013 51_[+5]_37 chr1:9802982-9803482 0.00013 57_[+5]_31 chr5:142215852-142216352 0.00013 67_[+5]_21 chr17:19507972-19508472 0.00014 5_[-5]_83 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF VATGAYSTCACC width=12 seqs=85 chr12:132445991-13244649 ( 20) GATGACGTCACC 1 chr19:996297-996797 ( 52) GATGACGTCACC 1 chr8:22109466-22109966 ( 29) GATGACGTCACC 1 chr10:124323112-12432361 ( 45) AATGACGTCACC 1 chr19:35612474-35612974 ( 29) GATGACGTCACT 1 chr7:98418869-98419369 ( 26) GATGACGTCACA 1 chr8:22178741-22179241 ( 10) AATGACCTCACC 1 chr19:1021413-1021913 ( 68) CATGACGTCACA 1 chr17:78558298-78558798 ( 14) GATGACATCACC 1 chr10:94673534-94674034 ( 1) GATGACATCACC 1 chr17:51046593-51047093 ( 24) AATGACGTCATC 1 chr1:3992028-3992528 ( 81) CATGACATCACC 1 chr17:74514127-74514627 ( 44) CATGACATCACC 1 chr1:1000656-1001156 ( 60) CATGACGTCATC 1 chr10:77350593-77351093 ( 4) GATGACCTCACA 1 chr6:108558306-108558806 ( 44) GATGATGTCATC 1 chr6:169395998-169396498 ( 25) AATGACCTCACT 1 chr1:68217014-68217514 ( 55) CATGAGGTCACC 1 chr8:144456684-144457184 ( 17) GATGACATCACA 1 chr15:70494066-70494566 ( 85) GATGACCTCATC 1 chr19:35628752-35629252 ( 58) CATGACGTCATA 1 chr1:156660080-156660580 ( 60) GATGAGGTCACT 1 chr7:158097519-158098019 ( 57) AATGATGTCATA 1 chr17:21359020-21359520 ( 23) GATGAAGTCACT 1 chr7:116218161-116218661 ( 42) CATGATATCACT 1 chr20:3173059-3173559 ( 32) CATGACATCATC 1 chr1:233112858-233113358 ( 61) GCTGATGTCACC 1 chr19:43572061-43572561 ( 69) CATTATGTCACC 1 chr1:229221162-229221662 ( 5) GATGAAGTCATC 1 chr7:157880964-157881464 ( 17) CATGACCTCATT 1 chr5:17305875-17306375 ( 47) AATGATGTCAGC 1 chr1:16159046-16159546 ( 80) GATTATGTCACT 1 chr16:73070486-73070986 ( 12) AATGATGTCAGC 1 chr7:151727580-151728080 ( 29) GATGAACTCACT 1 chr10:5548771-5549271 ( 75) GGTGACGTCACC 1 chr1:17597003-17597503 ( 47) AATTATCTCACC 1 chr12:113245733-11324623 ( 89) GCTGATGTCACA 1 chr6:6678172-6678672 ( 27) AATGAGATCACA 1 chr22:37905058-37905558 ( 8) GGTGATGTCACC 1 chr1:201713359-201713859 ( 56) CATGAGCTCATC 1 chr22:32539579-32540079 ( 81) CATGATATCATT 1 chr1:175841755-175842255 ( 27) GCTGAGGTCACC 1 chr15:68623304-68623804 ( 20) GCTGACCTCACT 1 chr8:37359498-37359998 ( 28) GCTGAGGTCACC 1 chr10:103896194-10389669 ( 28) AATGATCTCAGC 1 chr3:138833396-138833896 ( 26) CATGACTTCACC 1 chr3:9731327-9731827 ( 41) ACTGAAGTCACC 1 chr3:14452053-14452553 ( 6) AGTGACCTCACC 1 chr16:3020700-3021200 ( 16) ACTGAAGTCACC 1 chr13:112213422-11221392 ( 81) AATGACCTCAGT 1 chr10:129440217-12944071 ( 78) GATGAACTCATA 1 chr18:48998085-48998585 ( 24) CATGATGTAACA 1 chr1:223992386-223992886 ( 56) CGTGACGTCACA 1 chr15:75104738-75105238 ( 64) CATGACCTCAGA 1 chr1:175470966-175471466 ( 20) AATGAACTCATT 1 chr17:60173295-60173795 ( 39) GATGACATCAGA 1 chr16:1971754-1972254 ( 87) GATGGCGTCACC 1 chr13:41696486-41696986 ( 13) GATGACATAACA 1 chr7:151079992-151080492 ( 11) CATTACCTCATT 1 chr17:3888450-3888950 ( 56) CCTGACGTCAGC 1 chr19:40602280-40602780 ( 44) GATGAGCTCACG 1 chr19:10416563-10417063 ( 5) GCTGACGTCACG 1 chr6:41767104-41767604 ( 37) AGTTACGTCACC 1 chr17:79020161-79020661 ( 49) ACTGAGATCACA 1 chr10:87845976-87846476 ( 24) CATTATGTCACG 1 chr7:44039050-44039550 ( 33) CATGGCCTCACC 1 chr1:27321855-27322355 ( 81) CATGGCGTCACT 1 chr1:228838378-228838878 ( 18) CCTGAGGTCATT 1 chr10:75379161-75379661 ( 27) AATAATGTCATT 1 chr10:50067611-50068111 ( 71) CCTGATGTCACG 1 chr15:70089037-70089537 ( 47) ACTTACCTCACT 1 chr1:31387527-31388027 ( 63) GACGACCTCACC 1 chr10:93209024-93209524 ( 25) TATGATCTCACT 1 chr2:109213990-109214490 ( 57) GATAAGATCACC 1 chr1:227953574-227954074 ( 79) AGTGAGCTCACA 1 chr11:9759514-9760014 ( 10) CATAAAGTCACA 1 chr9:126791449-126791949 ( 47) AATAATCTCATT 1 chr10:22552772-22553272 ( 55) CATGAGGTAATT 1 chr19:2529435-2529935 ( 14) AATGATCTAAGC 1 chr1:229148078-229148578 ( 61) CCTTATCTCATC 1 chr1:47690362-47690862 ( 25) AATTATCTAATC 1 chr10:3314556-3315056 ( 52) GGTGACTTCACA 1 chr1:9802982-9803482 ( 58) GATTAGATAACC 1 chr5:142215852-142216352 ( 68) GCTTATGTAACC 1 chr17:19507972-19508472 ( 6) CACGAGGTCACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 10.2906 E= 9.3e-025 31 17 50 -421 177 -68 -178 -1305 -1305 -358 -1305 216 -221 -1305 155 -75 215 -1305 -300 -1305 -121 74 -78 31 -40 12 84 -321 -1305 -1305 -1305 220 -140 170 -1305 -1305 220 -1305 -1305 -1305 -1305 125 -158 11 4 81 -258 11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 85 E= 9.3e-025 0.270588 0.317647 0.400000 0.011765 0.741176 0.176471 0.082353 0.000000 0.000000 0.023529 0.000000 0.976471 0.047059 0.000000 0.823529 0.129412 0.964706 0.000000 0.035294 0.000000 0.094118 0.470588 0.164706 0.270588 0.164706 0.305882 0.505882 0.023529 0.000000 0.000000 0.000000 1.000000 0.082353 0.917647 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.670588 0.094118 0.235294 0.223529 0.494118 0.047059 0.235294 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif VATGAYSTCACC MEME-5 regular expression -------------------------------------------------------------------------------- [GCA]ATGA[CT][GC]TCA[CT][CTA] -------------------------------------------------------------------------------- Time 2380.39 secs. ******************************************************************************** ******************************************************************************** MOTIF WKTRTTTDTTTW MEME-6 width = 12 sites = 66 llr = 661 E-value = 1.5e-018 ******************************************************************************** -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 Description -------------------------------------------------------------------------------- Simplified A 4::4:1:4:214 pos.-specific C :2::::::2111 probability G 24:5:::3:::: matrix T 44a1a9a38785 bits 2.2 * 2.0 * * * 1.8 * *** 1.5 * *** Relative 1.3 * *** * Entropy 1.1 * *** *** (14.4 bits) 0.9 * *** **** 0.7 * ***** **** 0.4 ************ 0.2 ************ 0.0 ------------ Multilevel TGTGTTTATTTT consensus AT A GC A sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr6:138088259-138088759 + 56 4.95e-08 TGAGTTTCCC TTTGTTTATTTT TGCAGCCAAC chr17:48492587-48493087 + 20 3.07e-07 AGGCGGATTC AGTGTTTATTTA GGCTGAGAGC chr17:75368255-75368755 + 68 3.07e-07 gcgtcaggcG TTTGtttttttt tttgttgttt chr12:56041724-56042224 - 47 3.07e-07 ATGCGTTCCT AGTGTTTATTTA TCCATGGAAC chr9:131735349-131735849 - 83 4.12e-07 TTCATG TTTGTTTGTTTT TGTCTGGACT chr5:17305875-17306375 - 69 4.12e-07 GAATCTCTAA TTTATTTGTTTA ACACGCAACT chr13:113493242-11349374 + 85 5.49e-07 TGATTGCCTC ATTGTTTGTTTT TAAG chr17:78624707-78625207 + 79 6.85e-07 gttgttacac agtattttttTA ACTTTTTCAT chr3:16482916-16483416 - 74 7.88e-07 AGTACTCTGA AGTGTTTGTTTT GCCTTTCCTT chr20:46085109-46085609 + 26 9.85e-07 ccTggagttc actgtttattta ataaaggaga chr10:103896194-10389669 - 56 1.08e-06 ACGTGACTCA TTTATTTACTTT CTTTATCCCA chr5:6419271-6419771 - 4 1.08e-06 TTAGTACATA ATTTTTTATTTA CAC chr17:19507972-19508472 + 89 1.53e-06 caAGGTTGGG TTTTTTTTTTTT chr6:158040319-158040819 - 15 1.53e-06 TCTTACATCC TTTTTTTTTTTT AATAGACTGA chr20:50661148-50661648 - 47 2.09e-06 TATGGAGATG TTTATTTTCTTT TGGTTATTAA chr8:27872510-27873010 - 62 2.41e-06 GTTAGTCTTC TTTATTTGCTTT GGGTGTGACT chr22:32539579-32540079 - 14 2.41e-06 ACCTTGTCCC AGTTTTTTTTTT TCTTGAGGAT chr1:167658543-167659043 + 59 2.41e-06 ccctttttat ggtatttttttt ttgtctctag chr6:3911802-3912302 - 1 2.80e-06 ATAGGGAGAG ATTGTTTTCTTT chr15:69143654-69144154 + 28 3.22e-06 cactgtgata ggtgtttgtttt ataggcttga chr6:43321930-43322430 - 41 3.22e-06 GTGTTGTGGT TTTGTTTTTATT CATCTCAAAG chr9:108543257-108543757 - 70 3.22e-06 TAGTGACAGC ATTATTTGCTTA CAAGATCAGG chr19:29875105-29875605 + 4 3.66e-06 TTA TTTATTTATCTT AAGGGTTGTC chr19:43572061-43572561 - 6 4.12e-06 GGGAGGGATT TGTGTTTTTATT ACTTA chr17:79020161-79020661 - 77 5.11e-06 ACTCGCTGGG TCTGTTTACTTA TTGCTGGAAA chr16:15590866-15591366 - 31 6.36e-06 CACTGTTTCA AGTGTTTATTCT GCCTCCGCTT chr1:228902971-228903471 + 22 6.36e-06 GCACCACTCC ACTGTTTATATT TGGTCATTTA chr17:43669979-43670479 + 86 6.36e-06 TTTACCCAGC AGTATTTTTTAA AAC chr10:3783793-3784293 - 84 7.14e-06 GCTGT GCTGTTTGTTTT TCGTCACAAA chr1:155127111-155127611 - 44 7.14e-06 CACACACGCG GCTGTTTGTTTT TGTTGGGTTT chr5:125485067-125485567 + 60 7.14e-06 CACGAATGGC TGTGTTTGTTAA GGAGTCACAC chr6:42147145-42147645 + 83 8.08e-06 CATGATCTTA Tttgtttctttt ggcaca chr10:99520006-99520506 + 30 8.08e-06 CTAGGATAAT GGTGTTTACTTT ACCGCGATAA chr6:170279924-170280424 - 14 8.08e-06 AATTCGTGTA GCTGTTTGTTTA GTGGGCGTGT chr17:78409176-78409676 + 36 9.16e-06 TGAGAATGTC ACTATTTTTATT GCCTTCCTGA chr3:4320401-4320901 - 19 9.16e-06 CCTGAGAGAC TTTATTTACATA AGACAATCTT chr14:99821630-99822130 + 84 1.22e-05 AGATAGCTAG AGTGTTTGTTCA CTCCC chr19:39033050-39033550 - 60 1.22e-05 CCAGCTAATT TTTGTATTTTTA GTAGAGACGG chr12:12891160-12891660 + 50 1.33e-05 GCACGGGGAC TTTATTTTCATA ACAGCATGAA chr6:33758745-33759245 - 57 1.33e-05 CTTACACTAC AGTTTTTATTAA CTCAGCATCC chr21:38907009-38907509 - 83 1.55e-05 TACTAG ACTGTTTGTTAA GGGCTGCACT chr1:228861083-228861583 - 80 1.69e-05 GTTGAGTCA TCTATTTCTTTT TTATCCACTT chr7:98418869-98419369 + 72 1.69e-05 CAGGGGCAGC TCTGTTTGTCTT GGAGATAAAC chr22:42855134-42855634 - 36 1.85e-05 TTTAGATTGA TGTGTTTATAAA GAGTGGGTCC chr5:142215852-142216352 + 48 1.85e-05 GAGATGAGTT GGTATTTATTTC CCTGCAAAGC chr6:168147170-168147670 - 78 2.03e-05 GGAATCCAAT ACTGTATATTTA CATTTGGGGT chr22:40711447-40711947 - 25 2.03e-05 AAATACTTGG TTTTTTTGTTCT GTTTTGTTTG chr15:58038593-58039093 + 74 2.03e-05 GTAAAACCAG AGTATTTACTCT AGTGCACATA chr5:124655948-124656448 - 12 2.03e-05 ATTGCCATAC ACTATTTGTTCA GATAAAGCCC chr22:38606557-38607057 + 45 2.40e-05 ATGTCTTAAA TTTATTTTCTTC TGGTGTCAGT chr1:16164156-16164656 - 13 2.63e-05 AGCCACTATG TTTATTTGCTCA TTCATTTAAC chr22:35894887-35895387 + 74 2.63e-05 ACACTCTCTC TGTATTTGCCTT CAGGGAATCT chr9:85743161-85743661 - 16 2.88e-05 ATGTAATGCT GCTATTTATCTT GTGTGGGTTA chr1:234700128-234700628 + 84 2.88e-05 ACTCAGAGGC ATTATTTATTAC TGTTA chr10:121500849-12150134 + 54 2.88e-05 CACGCGCCTG AGTATTTTCCTA GTGACGTTTT chr20:16257770-16258270 - 9 3.37e-05 AGGCAAGGTG TGTGTGTGTTTA GGATGGGC chr10:3061459-3061959 - 22 3.37e-05 GCTGCCTTCA AGTATGTGTTTA ACAAAGCACA chr1:41870087-41870587 - 88 3.61e-05 G TGTGATTATTTA ATTGCAACGT chr20:25237753-25238253 + 52 3.87e-05 tatgccacag tgtatttatcca ttccagtgat chr3:138833396-138833896 - 3 3.87e-05 TAATTAAATG AGTACTTATTTT GA chr15:95556832-95557332 + 34 3.87e-05 CTGTTTATTA GGTTTTTATCTT CTTATCAGAG chr3:123431547-123432047 - 83 5.58e-05 AGGCAA GTTGTTTATATC TAAGGGGTTT chr3:4741599-4742099 + 75 5.58e-05 ACTTCTGAGC GGTGTTTTCTAA CCTCAGGTTT chr1:46719610-46720110 + 4 9.80e-05 tgc agtttatttata ctctagaggg chr1:3402109-3402609 + 77 9.80e-05 CTTGACGACA ATAATTTATTAT ATGCACTGGA chr22:24517398-24517898 - 40 1.04e-04 GGACATAGCA ATTATATGCATA TTACACTGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:138088259-138088759 4.9e-08 55_[+6]_33 chr17:48492587-48493087 3.1e-07 19_[+6]_69 chr17:75368255-75368755 3.1e-07 67_[+6]_21 chr12:56041724-56042224 3.1e-07 46_[-6]_42 chr9:131735349-131735849 4.1e-07 82_[-6]_6 chr5:17305875-17306375 4.1e-07 68_[-6]_20 chr13:113493242-11349374 5.5e-07 84_[+6]_4 chr17:78624707-78625207 6.9e-07 78_[+6]_10 chr3:16482916-16483416 7.9e-07 73_[-6]_15 chr20:46085109-46085609 9.8e-07 25_[+6]_63 chr10:103896194-10389669 1.1e-06 55_[-6]_33 chr5:6419271-6419771 1.1e-06 3_[-6]_85 chr17:19507972-19508472 1.5e-06 88_[+6] chr6:158040319-158040819 1.5e-06 14_[-6]_74 chr20:50661148-50661648 2.1e-06 46_[-6]_42 chr8:27872510-27873010 2.4e-06 61_[-6]_27 chr22:32539579-32540079 2.4e-06 13_[-6]_75 chr1:167658543-167659043 2.4e-06 58_[+6]_30 chr6:3911802-3912302 2.8e-06 [-6]_88 chr15:69143654-69144154 3.2e-06 27_[+6]_61 chr6:43321930-43322430 3.2e-06 40_[-6]_48 chr9:108543257-108543757 3.2e-06 69_[-6]_19 chr19:29875105-29875605 3.7e-06 3_[+6]_85 chr19:43572061-43572561 4.1e-06 5_[-6]_83 chr17:79020161-79020661 5.1e-06 76_[-6]_12 chr16:15590866-15591366 6.4e-06 30_[-6]_58 chr1:228902971-228903471 6.4e-06 21_[+6]_67 chr17:43669979-43670479 6.4e-06 85_[+6]_3 chr10:3783793-3784293 7.1e-06 83_[-6]_5 chr1:155127111-155127611 7.1e-06 43_[-6]_45 chr5:125485067-125485567 7.1e-06 59_[+6]_29 chr6:42147145-42147645 8.1e-06 82_[+6]_6 chr10:99520006-99520506 8.1e-06 29_[+6]_59 chr6:170279924-170280424 8.1e-06 13_[-6]_75 chr17:78409176-78409676 9.2e-06 35_[+6]_53 chr3:4320401-4320901 9.2e-06 18_[-6]_70 chr14:99821630-99822130 1.2e-05 83_[+6]_5 chr19:39033050-39033550 1.2e-05 59_[-6]_29 chr12:12891160-12891660 1.3e-05 49_[+6]_39 chr6:33758745-33759245 1.3e-05 56_[-6]_32 chr21:38907009-38907509 1.5e-05 82_[-6]_6 chr1:228861083-228861583 1.7e-05 79_[-6]_9 chr7:98418869-98419369 1.7e-05 71_[+6]_17 chr22:42855134-42855634 1.9e-05 35_[-6]_53 chr5:142215852-142216352 1.9e-05 47_[+6]_41 chr6:168147170-168147670 2e-05 77_[-6]_11 chr22:40711447-40711947 2e-05 24_[-6]_64 chr15:58038593-58039093 2e-05 73_[+6]_15 chr5:124655948-124656448 2e-05 11_[-6]_77 chr22:38606557-38607057 2.4e-05 44_[+6]_44 chr1:16164156-16164656 2.6e-05 12_[-6]_76 chr22:35894887-35895387 2.6e-05 73_[+6]_15 chr9:85743161-85743661 2.9e-05 15_[-6]_73 chr1:234700128-234700628 2.9e-05 83_[+6]_5 chr10:121500849-12150134 2.9e-05 53_[+6]_35 chr20:16257770-16258270 3.4e-05 8_[-6]_80 chr10:3061459-3061959 3.4e-05 21_[-6]_67 chr1:41870087-41870587 3.6e-05 87_[-6]_1 chr20:25237753-25238253 3.9e-05 51_[+6]_37 chr3:138833396-138833896 3.9e-05 2_[-6]_86 chr15:95556832-95557332 3.9e-05 33_[+6]_55 chr3:123431547-123432047 5.6e-05 82_[-6]_6 chr3:4741599-4742099 5.6e-05 74_[+6]_14 chr1:46719610-46720110 9.8e-05 3_[+6]_85 chr1:3402109-3402609 9.8e-05 76_[+6]_12 chr22:24517398-24517898 0.0001 39_[-6]_49 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WKTRTTTDTTTW width=12 seqs=66 chr6:138088259-138088759 ( 56) TTTGTTTATTTT 1 chr17:48492587-48493087 ( 20) AGTGTTTATTTA 1 chr17:75368255-75368755 ( 68) TTTGTTTTTTTT 1 chr12:56041724-56042224 ( 47) AGTGTTTATTTA 1 chr9:131735349-131735849 ( 83) TTTGTTTGTTTT 1 chr5:17305875-17306375 ( 69) TTTATTTGTTTA 1 chr13:113493242-11349374 ( 85) ATTGTTTGTTTT 1 chr17:78624707-78625207 ( 79) AGTATTTTTTTA 1 chr3:16482916-16483416 ( 74) AGTGTTTGTTTT 1 chr20:46085109-46085609 ( 26) ACTGTTTATTTA 1 chr10:103896194-10389669 ( 56) TTTATTTACTTT 1 chr5:6419271-6419771 ( 4) ATTTTTTATTTA 1 chr17:19507972-19508472 ( 89) TTTTTTTTTTTT 1 chr6:158040319-158040819 ( 15) TTTTTTTTTTTT 1 chr20:50661148-50661648 ( 47) TTTATTTTCTTT 1 chr8:27872510-27873010 ( 62) TTTATTTGCTTT 1 chr22:32539579-32540079 ( 14) AGTTTTTTTTTT 1 chr1:167658543-167659043 ( 59) GGTATTTTTTTT 1 chr6:3911802-3912302 ( 1) ATTGTTTTCTTT 1 chr15:69143654-69144154 ( 28) GGTGTTTGTTTT 1 chr6:43321930-43322430 ( 41) TTTGTTTTTATT 1 chr9:108543257-108543757 ( 70) ATTATTTGCTTA 1 chr19:29875105-29875605 ( 4) TTTATTTATCTT 1 chr19:43572061-43572561 ( 6) TGTGTTTTTATT 1 chr17:79020161-79020661 ( 77) TCTGTTTACTTA 1 chr16:15590866-15591366 ( 31) AGTGTTTATTCT 1 chr1:228902971-228903471 ( 22) ACTGTTTATATT 1 chr17:43669979-43670479 ( 86) AGTATTTTTTAA 1 chr10:3783793-3784293 ( 84) GCTGTTTGTTTT 1 chr1:155127111-155127611 ( 44) GCTGTTTGTTTT 1 chr5:125485067-125485567 ( 60) TGTGTTTGTTAA 1 chr6:42147145-42147645 ( 83) TTTGTTTCTTTT 1 chr10:99520006-99520506 ( 30) GGTGTTTACTTT 1 chr6:170279924-170280424 ( 14) GCTGTTTGTTTA 1 chr17:78409176-78409676 ( 36) ACTATTTTTATT 1 chr3:4320401-4320901 ( 19) TTTATTTACATA 1 chr14:99821630-99822130 ( 84) AGTGTTTGTTCA 1 chr19:39033050-39033550 ( 60) TTTGTATTTTTA 1 chr12:12891160-12891660 ( 50) TTTATTTTCATA 1 chr6:33758745-33759245 ( 57) AGTTTTTATTAA 1 chr21:38907009-38907509 ( 83) ACTGTTTGTTAA 1 chr1:228861083-228861583 ( 80) TCTATTTCTTTT 1 chr7:98418869-98419369 ( 72) TCTGTTTGTCTT 1 chr22:42855134-42855634 ( 36) TGTGTTTATAAA 1 chr5:142215852-142216352 ( 48) GGTATTTATTTC 1 chr6:168147170-168147670 ( 78) ACTGTATATTTA 1 chr22:40711447-40711947 ( 25) TTTTTTTGTTCT 1 chr15:58038593-58039093 ( 74) AGTATTTACTCT 1 chr5:124655948-124656448 ( 12) ACTATTTGTTCA 1 chr22:38606557-38607057 ( 45) TTTATTTTCTTC 1 chr1:16164156-16164656 ( 13) TTTATTTGCTCA 1 chr22:35894887-35895387 ( 74) TGTATTTGCCTT 1 chr9:85743161-85743661 ( 16) GCTATTTATCTT 1 chr1:234700128-234700628 ( 84) ATTATTTATTAC 1 chr10:121500849-12150134 ( 54) AGTATTTTCCTA 1 chr20:16257770-16258270 ( 9) TGTGTGTGTTTA 1 chr10:3061459-3061959 ( 22) AGTATGTGTTTA 1 chr1:41870087-41870587 ( 88) TGTGATTATTTA 1 chr20:25237753-25238253 ( 52) TGTATTTATCCA 1 chr3:138833396-138833896 ( 3) AGTACTTATTTT 1 chr15:95556832-95557332 ( 34) GGTTTTTATCTT 1 chr3:123431547-123432047 ( 83) GTTGTTTATATC 1 chr3:4741599-4742099 ( 75) GGTGTTTTCTAA 1 chr1:46719610-46720110 ( 4) AGTTTATTTATA 1 chr1:3402109-3402609 ( 77) ATAATTTATTAT 1 chr22:24517398-24517898 ( 40) ATTATATGCATA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 11.8166 E= 1.5e-018 91 -1269 -76 96 -1269 -52 54 85 -384 -1269 -1269 218 91 -1269 74 -85 -384 -421 -1269 215 -185 -1269 -322 206 -1269 -1269 -1269 220 80 -322 17 32 -1269 -22 -1269 180 -52 -141 -1269 177 -85 -141 -1269 183 101 -222 -1269 120 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 66 E= 1.5e-018 0.409091 0.000000 0.166667 0.424242 0.000000 0.196970 0.409091 0.393939 0.015152 0.000000 0.000000 0.984848 0.409091 0.000000 0.469697 0.121212 0.015152 0.015152 0.000000 0.969697 0.060606 0.000000 0.030303 0.909091 0.000000 0.000000 0.000000 1.000000 0.378788 0.030303 0.318182 0.272727 0.000000 0.242424 0.000000 0.757576 0.151515 0.106061 0.000000 0.742424 0.121212 0.106061 0.000000 0.772727 0.439394 0.060606 0.000000 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WKTRTTTDTTTW MEME-6 regular expression -------------------------------------------------------------------------------- [TA][GT]T[GA]TTT[AGT][TC]TT[TA] -------------------------------------------------------------------------------- Time 2813.52 secs. ******************************************************************************** ******************************************************************************** MOTIF GTGTGYSTRTGTGYGTGTGHGT MEME-7 width = 22 sites = 20 llr = 293 E-value = 6.5e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 Description -------------------------------------------------------------------------------- Simplified A :111:1134:11113111152: pos.-specific C 1322:351:312:511:::31: probability G 9:8:92517:82927:a19:71 matrix T 17:725:6:8:613:9:91329 bits 2.2 2.0 1.8 * 1.5 ** * Relative 1.3 * * * **** * Entropy 1.1 * * ** * **** * (21.1 bits) 0.9 ***** *** * **** * 0.7 ***** ***** * ****** * 0.4 ***** ******* ******** 0.2 ********************** 0.0 ---------------------- Multilevel GTGTGTCTGTGTGCGTGTGAGT consensus C C CGAAC G TA T sequence G C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ---------------------- chr17:38726108-38726608 + 39 1.91e-11 GCCCGTCTCA gtgtgtgagtgtgtgtgtgcgt gcatgtgtgt chr7:191555-192055 - 10 4.65e-11 GTGTTTGTGT GTGCGTCTGTGTGCATGTGTGT GTGCACATG chr17:45127535-45128035 + 35 1.44e-10 gcgtgagaca gtgtgtgtgtatgagtgtgagt gaatgtgtgt chr16:88882193-88882693 + 42 1.15e-09 CTGTGTGTGG GTGTGGCTGTGTGCGTGGGCGT GGCTGTGTGC chr22:42648692-42649192 - 5 8.54e-09 TGAATGGCTT GAGAGTGAATGTGTGTGTGAGT GTGA chr9:135967565-135968065 + 76 1.31e-08 tgggcgtgtt gtgtgcatgtgtgcatatgtgt gca chr13:98487922-98488422 - 71 1.31e-08 CTCATGTG GTCTTCCCGTGTGTGTGTGTGT GTGTGTGTGT chr16:12120422-12120922 + 10 6.32e-08 CGTAATCAT TTGTGTGAATGGGCCTGTGCGT CATCTGGCTG chr19:36604694-36605194 - 40 9.08e-08 CTGTGGCTGC GTCCGTGTGTGGTGGTGTGAGT GGGCGCGCCT chr1:42165880-42166380 + 75 9.93e-08 tTAAGGGGGG GTGTGTCTGCGGAGATGTGTAT GTCT chr22:42964965-42965465 + 29 1.08e-07 cacccactgt gtgtgtctatgtggatgaaatt cgaaaccaag chr17:50101365-50101865 - 8 1.08e-07 ATGTGCATGC CTGTGGGTGTGTGCGAGGGTGT GCCCTGT chr22:35840385-35840885 + 19 2.53e-07 TTGGTGTACG CTGTGCGCACGCgtgtgtgcgt gtgtgcgtgt chr12:52069573-52070073 + 60 2.74e-07 AGAGAGCAAC GCATGACTATCTGCGTGTGCTT CTGTGACTAC chr19:33274103-33274603 + 46 3.21e-07 gtgtgtaccc gtgtgactacaagcatgtgtat gagtgcacac chr1:16644449-16644949 - 71 3.76e-07 GAGGCTCA GCGCGCGAGCGTGCGCGTGATT TGGCCCTGAA chr12:131128958-13112945 + 53 4.40e-07 TGACAGCCCC GCCCTGCTGTCTGGGTGTGAGT GACAGGCCCG chr2:10014774-10015274 + 71 8.01e-07 AGGTGGGCAG GCGTGCGTATGGGCGAGTTAGG TGGACAGG chr10:42782490-42782990 + 67 9.25e-07 TTTCCCTCCG GCGAGTCAGCGCGACTGTGAAT TTCCGTTTCC chr14:90383184-90383684 + 43 3.50e-06 GCTACAGACC GCGTTCCGGTGCGTGTGTGACG ACACCGCCGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:38726108-38726608 1.9e-11 38_[+7]_40 chr7:191555-192055 4.7e-11 9_[-7]_69 chr17:45127535-45128035 1.4e-10 34_[+7]_44 chr16:88882193-88882693 1.2e-09 41_[+7]_37 chr22:42648692-42649192 8.5e-09 4_[-7]_74 chr9:135967565-135968065 1.3e-08 75_[+7]_3 chr13:98487922-98488422 1.3e-08 70_[-7]_8 chr16:12120422-12120922 6.3e-08 9_[+7]_69 chr19:36604694-36605194 9.1e-08 39_[-7]_39 chr1:42165880-42166380 9.9e-08 74_[+7]_4 chr22:42964965-42965465 1.1e-07 28_[+7]_50 chr17:50101365-50101865 1.1e-07 7_[-7]_71 chr22:35840385-35840885 2.5e-07 18_[+7]_60 chr12:52069573-52070073 2.7e-07 59_[+7]_19 chr19:33274103-33274603 3.2e-07 45_[+7]_33 chr1:16644449-16644949 3.8e-07 70_[-7]_8 chr12:131128958-13112945 4.4e-07 52_[+7]_26 chr2:10014774-10015274 8e-07 70_[+7]_8 chr10:42782490-42782990 9.2e-07 66_[+7]_12 chr14:90383184-90383684 3.5e-06 42_[+7]_36 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GTGTGYSTRTGTGYGTGTGHGT width=22 seqs=20 chr17:38726108-38726608 ( 39) GTGTGTGAGTGTGTGTGTGCGT 1 chr7:191555-192055 ( 10) GTGCGTCTGTGTGCATGTGTGT 1 chr17:45127535-45128035 ( 35) GTGTGTGTGTATGAGTGTGAGT 1 chr16:88882193-88882693 ( 42) GTGTGGCTGTGTGCGTGGGCGT 1 chr22:42648692-42649192 ( 5) GAGAGTGAATGTGTGTGTGAGT 1 chr9:135967565-135968065 ( 76) GTGTGCATGTGTGCATATGTGT 1 chr13:98487922-98488422 ( 71) GTCTTCCCGTGTGTGTGTGTGT 1 chr16:12120422-12120922 ( 10) TTGTGTGAATGGGCCTGTGCGT 1 chr19:36604694-36605194 ( 40) GTCCGTGTGTGGTGGTGTGAGT 1 chr1:42165880-42166380 ( 75) GTGTGTCTGCGGAGATGTGTAT 1 chr22:42964965-42965465 ( 29) GTGTGTCTATGTGGATGAAATT 1 chr17:50101365-50101865 ( 8) CTGTGGGTGTGTGCGAGGGTGT 1 chr22:35840385-35840885 ( 19) CTGTGCGCACGCGTGTGTGCGT 1 chr12:52069573-52070073 ( 60) GCATGACTATCTGCGTGTGCTT 1 chr19:33274103-33274603 ( 46) GTGTGACTACAAGCATGTGTAT 1 chr1:16644449-16644949 ( 71) GCGCGCGAGCGTGCGCGTGATT 1 chr12:131128958-13112945 ( 53) GCCCTGCTGTCTGGGTGTGAGT 1 chr2:10014774-10015274 ( 71) GCGTGCGTATGGGCGAGTTAGG 1 chr10:42782490-42782990 ( 67) GCGAGTCAGCGCGACTGTGAAT 1 chr14:90383184-90383684 ( 43) GCGTTCCGGTGCGTGTGTGACG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 22 n= 47400 bayes= 12.6844 E= 6.5e-003 -1097 -149 159 -212 -212 9 -1097 158 -212 -91 150 -1097 -112 -50 -1097 168 -1097 -1097 159 -54 -112 9 -91 105 -212 83 67 -1097 20 -149 -249 146 68 -1097 120 -1097 -1097 -17 -1097 178 -112 -149 150 -1097 -212 -91 -50 146 -212 -1097 167 -212 -112 67 -50 20 20 -149 120 -1097 -112 -249 -1097 196 -212 -1097 175 -1097 -212 -1097 -149 196 -212 -1097 167 -212 105 -17 -1097 46 -54 -249 120 -54 -1097 -1097 -149 205 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 22 nsites= 20 E= 6.5e-003 0.000000 0.100000 0.850000 0.050000 0.050000 0.300000 0.000000 0.650000 0.050000 0.150000 0.800000 0.000000 0.100000 0.200000 0.000000 0.700000 0.000000 0.000000 0.850000 0.150000 0.100000 0.300000 0.150000 0.450000 0.050000 0.500000 0.450000 0.000000 0.250000 0.100000 0.050000 0.600000 0.350000 0.000000 0.650000 0.000000 0.000000 0.250000 0.000000 0.750000 0.100000 0.100000 0.800000 0.000000 0.050000 0.150000 0.200000 0.600000 0.050000 0.000000 0.900000 0.050000 0.100000 0.450000 0.200000 0.250000 0.250000 0.100000 0.650000 0.000000 0.100000 0.050000 0.000000 0.850000 0.050000 0.000000 0.950000 0.000000 0.050000 0.000000 0.100000 0.850000 0.050000 0.000000 0.900000 0.050000 0.450000 0.250000 0.000000 0.300000 0.150000 0.050000 0.650000 0.150000 0.000000 0.000000 0.100000 0.900000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTGTGYSTRTGTGYGTGTGHGT MEME-7 regular expression -------------------------------------------------------------------------------- G[TC]G[TC]G[TC][CG][TA][GA][TC]G[TG]G[CTG][GA]TGTG[ATC]GT -------------------------------------------------------------------------------- Time 3237.76 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTATGAGSTSW MEME-8 width = 12 sites = 37 llr = 390 E-value = 2.5e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 Description -------------------------------------------------------------------------------- Simplified A ::3a:1a:1114 pos.-specific C ::::2::1622: probability G :::::9:83:51 matrix T aa7:7::11624 bits 2.2 ** * 2.0 ** * * 1.8 ** * * 1.5 ** * * Relative 1.3 **** ** Entropy 1.1 ******* (15.2 bits) 0.9 ******** 0.7 ******** * * 0.4 ********** * 0.2 ************ 0.0 ------------ Multilevel TTTATGAGCTGA consensus A C GCCT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------ chr5:175378373-175378873 - 65 6.45e-08 TCCAAGAGGT TTTATGAGCTGA AAACATAAAT chr8:27974341-27974841 - 3 6.45e-08 CTACCTGCTG TTTATGAGCTGT GG chr5:94469755-94470255 - 2 2.43e-07 TACAAAGCTT TTTATGAGGTGT G chr7:104883831-104884331 - 76 7.95e-07 GGTATAGGTA TTAATGAGCTTT CCAGCTCATT chr10:75379161-75379661 + 59 7.95e-07 AGTAGATCTG TTTACGAGCTGA TTAAATTGTA chr17:51703409-51703909 + 45 8.60e-07 GGGTCCTCCC TTAATGAGGTGT GCGATGTACA chr12:13098524-13099024 - 45 9.24e-07 GGGGGTGCAG TTTATGAGCAGA GGCAATAAAA chr3:4320401-4320901 - 36 9.89e-07 CTAAACAACT TTTATGACCTGA GAGACTTTAT chr20:4041741-4042241 - 44 1.19e-06 AACCAGAGAC TTTATGAGCCCA GGAATGGGCC chr8:37359498-37359998 + 71 2.99e-06 TCACGATGAA TTTATGAGGCCA ATTTTATTGG chr3:16482916-16483416 - 54 3.66e-06 TTGCCTTTCC TTAATGAGGTAT TTATTACCTC chr10:93209024-93209524 + 79 3.66e-06 TTATGATCTG TTTATGATCTTA CTGCTTATGA chr8:37329665-37330165 + 53 3.66e-06 CGGCTGTGAC TTTACGAGGTCA TAAAGAAAAC chr6:43321930-43322430 - 4 4.38e-06 TATACCTTCT TTTATGAGTTCT TTG chr10:71236245-71236745 - 40 4.38e-06 CGGCTTCATA TTTACGAGCTGG CTCTGAAGGG chr15:70494066-70494566 + 45 5.16e-06 tgttaagccc ttaatgagcatt atctcattta chr9:136189500-136190000 + 43 5.42e-06 GACACTTAGT TTAATGAGGAGA GTTTGCGTAA chr10:22552772-22553272 - 86 6.28e-06 AGT TTTATGAGGTAG GATTATACTT chr22:45934591-45935091 + 8 6.28e-06 TTTGCTT TTAATGAGCCAA ACCCTCTGGT chr7:132485139-132485639 + 31 7.18e-06 CAAGTGGAAG TTTATGATGTTT TGGTTCACAA chr1:61091443-61091943 + 26 7.18e-06 GTAAAGCTAA TTTATGACCAGT CTTTACCAGA chr15:70091903-70092403 - 32 9.21e-06 AGCAAACAAG TTTATCAGCTGA CCTGTTTAGC chr15:69143654-69144154 - 47 9.21e-06 TCGTGAGGAT TTAATGAGATCA AGCCTATAAA chr17:76853811-76854311 - 70 9.21e-06 CCAGCCCGGT TTTACGAGATGA AAGAGTTATG chr1:175470966-175471466 - 69 9.21e-06 AATAAAGATT TTTACAAGCTGT GATGCAACAA chr1:47577925-47578425 + 42 9.21e-06 cccaacaaag tttacaagctGT CCCTGCTGAC chr12:54033448-54033948 - 41 1.09e-05 AGTGGACAGT TTTACGAGCCAT TGATGCCTGG chr9:1458445-1458945 + 10 1.19e-05 AATGACACA TTTATGACCACT TGGTGGCTGA chr18:26468980-26469480 + 83 1.19e-05 ATAGCAGGTC TTTAAGAGCTCT GGAATC chr3:42819886-42820386 - 17 1.34e-05 GTCAACTACA TTTATGAGTCCT CAATTTATTA chr17:43669979-43670479 + 38 1.77e-05 AAACCGGGGA TTTATGTGGTGT GGGAACAGCT chr1:17597003-17597503 + 84 1.86e-05 TTATGGCTCT TTTATGACCCGG AGGCC chr7:151079992-151080492 - 74 1.96e-05 ACTAACCCGG TTAATGACCTCG GGCTTAACTT chr18:63457939-63458439 - 45 2.27e-05 AGCCTCATCT TTTACGATGTTA TGGTTAGAAT chr19:35248581-35249081 - 76 2.51e-05 TCTGGAAGTT TTAATGAGCGTA AACGACGTGG chr22:24517398-24517898 - 74 2.51e-05 TCAATCATTT TTAATAAGCCTA ATAGGCTGCT chr19:2983957-2984457 + 75 3.91e-05 AAATTGCGCA TTAACGAGGCGG GGTGAATTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:175378373-175378873 6.5e-08 64_[-8]_24 chr8:27974341-27974841 6.5e-08 2_[-8]_86 chr5:94469755-94470255 2.4e-07 1_[-8]_87 chr7:104883831-104884331 8e-07 75_[-8]_13 chr10:75379161-75379661 8e-07 58_[+8]_30 chr17:51703409-51703909 8.6e-07 44_[+8]_44 chr12:13098524-13099024 9.2e-07 44_[-8]_44 chr3:4320401-4320901 9.9e-07 35_[-8]_53 chr20:4041741-4042241 1.2e-06 43_[-8]_45 chr8:37359498-37359998 3e-06 70_[+8]_18 chr3:16482916-16483416 3.7e-06 53_[-8]_35 chr10:93209024-93209524 3.7e-06 78_[+8]_10 chr8:37329665-37330165 3.7e-06 52_[+8]_36 chr6:43321930-43322430 4.4e-06 3_[-8]_85 chr10:71236245-71236745 4.4e-06 39_[-8]_49 chr15:70494066-70494566 5.2e-06 44_[+8]_44 chr9:136189500-136190000 5.4e-06 42_[+8]_46 chr10:22552772-22553272 6.3e-06 85_[-8]_3 chr22:45934591-45935091 6.3e-06 7_[+8]_81 chr7:132485139-132485639 7.2e-06 30_[+8]_58 chr1:61091443-61091943 7.2e-06 25_[+8]_63 chr15:70091903-70092403 9.2e-06 31_[-8]_57 chr15:69143654-69144154 9.2e-06 46_[-8]_42 chr17:76853811-76854311 9.2e-06 69_[-8]_19 chr1:175470966-175471466 9.2e-06 68_[-8]_20 chr1:47577925-47578425 9.2e-06 41_[+8]_47 chr12:54033448-54033948 1.1e-05 40_[-8]_48 chr9:1458445-1458945 1.2e-05 9_[+8]_79 chr18:26468980-26469480 1.2e-05 82_[+8]_6 chr3:42819886-42820386 1.3e-05 16_[-8]_72 chr17:43669979-43670479 1.8e-05 37_[+8]_51 chr1:17597003-17597503 1.9e-05 83_[+8]_5 chr7:151079992-151080492 2e-05 73_[-8]_15 chr18:63457939-63458439 2.3e-05 44_[-8]_44 chr19:35248581-35249081 2.5e-05 75_[-8]_13 chr22:24517398-24517898 2.5e-05 73_[-8]_15 chr19:2983957-2984457 3.9e-05 74_[+8]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTATGAGSTSW width=12 seqs=37 chr5:175378373-175378873 ( 65) TTTATGAGCTGA 1 chr8:27974341-27974841 ( 3) TTTATGAGCTGT 1 chr5:94469755-94470255 ( 2) TTTATGAGGTGT 1 chr7:104883831-104884331 ( 76) TTAATGAGCTTT 1 chr10:75379161-75379661 ( 59) TTTACGAGCTGA 1 chr17:51703409-51703909 ( 45) TTAATGAGGTGT 1 chr12:13098524-13099024 ( 45) TTTATGAGCAGA 1 chr3:4320401-4320901 ( 36) TTTATGACCTGA 1 chr20:4041741-4042241 ( 44) TTTATGAGCCCA 1 chr8:37359498-37359998 ( 71) TTTATGAGGCCA 1 chr3:16482916-16483416 ( 54) TTAATGAGGTAT 1 chr10:93209024-93209524 ( 79) TTTATGATCTTA 1 chr8:37329665-37330165 ( 53) TTTACGAGGTCA 1 chr6:43321930-43322430 ( 4) TTTATGAGTTCT 1 chr10:71236245-71236745 ( 40) TTTACGAGCTGG 1 chr15:70494066-70494566 ( 45) TTAATGAGCATT 1 chr9:136189500-136190000 ( 43) TTAATGAGGAGA 1 chr10:22552772-22553272 ( 86) TTTATGAGGTAG 1 chr22:45934591-45935091 ( 8) TTAATGAGCCAA 1 chr7:132485139-132485639 ( 31) TTTATGATGTTT 1 chr1:61091443-61091943 ( 26) TTTATGACCAGT 1 chr15:70091903-70092403 ( 32) TTTATCAGCTGA 1 chr15:69143654-69144154 ( 47) TTAATGAGATCA 1 chr17:76853811-76854311 ( 70) TTTACGAGATGA 1 chr1:175470966-175471466 ( 69) TTTACAAGCTGT 1 chr1:47577925-47578425 ( 42) TTTACAAGCTGT 1 chr12:54033448-54033948 ( 41) TTTACGAGCCAT 1 chr9:1458445-1458945 ( 10) TTTATGACCACT 1 chr18:26468980-26469480 ( 83) TTTAAGAGCTCT 1 chr3:42819886-42820386 ( 17) TTTATGAGTCCT 1 chr17:43669979-43670479 ( 38) TTTATGTGGTGT 1 chr1:17597003-17597503 ( 84) TTTATGACCCGG 1 chr7:151079992-151080492 ( 74) TTAATGACCTCG 1 chr18:63457939-63458439 ( 45) TTTACGATGTTA 1 chr19:35248581-35249081 ( 76) TTAATGAGCGTA 1 chr22:24517398-24517898 ( 74) TTAATAAGCCTA 1 chr19:2983957-2984457 ( 75) TTAACGAGGCGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 12 n= 53400 bayes= 11.3677 E= 2.5e+000 -1185 -1185 -1185 220 -1185 -1185 -1185 220 45 -1185 -1185 169 220 -1185 -1185 -1185 -301 -21 -1185 174 -143 -338 166 -1185 216 -1185 -1185 -301 -1185 -106 147 -143 -201 108 8 -201 -69 -38 -338 151 -101 -21 70 -20 99 -1185 -106 99 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 12 nsites= 37 E= 2.5e+000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.297297 0.000000 0.000000 0.702703 1.000000 0.000000 0.000000 0.000000 0.027027 0.243243 0.000000 0.729730 0.081081 0.027027 0.891892 0.000000 0.972973 0.000000 0.000000 0.027027 0.000000 0.135135 0.783784 0.081081 0.054054 0.594595 0.297297 0.054054 0.135135 0.216216 0.027027 0.621622 0.108108 0.243243 0.459459 0.189189 0.432432 0.000000 0.135135 0.432432 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTATGAGSTSW MEME-8 regular expression -------------------------------------------------------------------------------- TT[TA]A[TC]GAG[CG][TC][GC][AT] -------------------------------------------------------------------------------- Time 3659.08 secs. ******************************************************************************** ******************************************************************************** MOTIF TGTTTACARAR MEME-9 width = 11 sites = 21 llr = 244 E-value = 2.7e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 Description -------------------------------------------------------------------------------- Simplified A :1:::a19375 pos.-specific C ::::::91::: probability G :9::1:::6:5 matrix T a:aa9:::12: bits 2.2 * * 2.0 * ** * 1.8 * **** * 1.5 * **** * Relative 1.3 ******** Entropy 1.1 ******** * (16.8 bits) 0.9 ******** ** 0.7 *********** 0.4 *********** 0.2 *********** 0.0 ----------- Multilevel TGTTTACAGAA consensus ATG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ----------- chr20:53609871-53610371 - 40 2.03e-07 CTCATTGAGT TGTTTACAAAA GGACTGTACC chr3:138833396-138833896 + 62 2.03e-07 CCCACAATGA TGTTTACAAAA GCACTTGTCA chr3:14452053-14452553 - 38 3.51e-07 ACGCTACTTC TGTTTACAGAG GAGAGAAGAG chr17:57569837-57570337 + 55 3.51e-07 attaaaatgg tgtttacagag agtttttaaa chr22:23218718-23219218 + 32 3.51e-07 GAGGAAGCGG TGTTTACAGAG CGGCCAGCTG chr7:157880964-157881464 + 49 5.80e-07 GAGATGGGGG TGTTTACAGTA GTCATTATGG chr3:16482916-16483416 + 34 1.56e-06 GCAGGTATCA TATTTACAGAG AGGTAATAAA chr22:40711447-40711947 + 42 1.56e-06 aaaaaCCAag tatttacagag acatgagtca chr1:224615791-224616291 + 46 1.56e-06 CAGACGCACG TGTTTAAAGAG TCCCTGCTCC chr10:87845976-87846476 + 9 2.15e-06 cgggctgt tgttgacagaa acgtcattat chr6:33758745-33759245 - 34 2.41e-06 CAGCATCCCA TGTTTACATTA GTGTTACGAC chr1:86774478-86774978 + 18 2.64e-06 CTCTCTCAAC TGTTTACCAAA GTATTAAAAA chr6:6678172-6678672 - 67 2.64e-06 TGATAACTAC TGTTTACCAAA CACTTACTGT chr1:65469938-65470438 - 40 3.16e-06 GCACAATAAG TGTTTAAAATA GAATGCTATT chr6:3911802-3912302 - 24 3.87e-06 TCACAGGGAA TGTTTAAAGTG CATAGGGAGA chr1:167658543-167659043 - 89 3.87e-06 C TGTTTACAGCA GCAAAACACT chr21:29217762-29218262 - 82 4.42e-06 AAGTGGGA TGTTGACAAAG GCGTTAAAGA chr10:124323112-12432361 + 72 5.11e-06 ACTCGCATTC TGTTTACAAGA ACTCACCACA chr17:78624707-78625207 - 58 5.91e-06 GTGTAACAAC TATTTACATAG CACTTACACT chr17:60173295-60173795 + 77 6.99e-06 GAGGCAATTA TGTCTACAGAG CTTTTGGCTA chr15:58038593-58039093 - 34 8.62e-06 AAATGTGCTC AGTTTACAGTA ATGAGCTTGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:53609871-53610371 2e-07 39_[-9]_50 chr3:138833396-138833896 2e-07 61_[+9]_28 chr3:14452053-14452553 3.5e-07 37_[-9]_52 chr17:57569837-57570337 3.5e-07 54_[+9]_35 chr22:23218718-23219218 3.5e-07 31_[+9]_58 chr7:157880964-157881464 5.8e-07 48_[+9]_41 chr3:16482916-16483416 1.6e-06 33_[+9]_56 chr22:40711447-40711947 1.6e-06 41_[+9]_48 chr1:224615791-224616291 1.6e-06 45_[+9]_44 chr10:87845976-87846476 2.1e-06 8_[+9]_81 chr6:33758745-33759245 2.4e-06 33_[-9]_56 chr1:86774478-86774978 2.6e-06 17_[+9]_72 chr6:6678172-6678672 2.6e-06 66_[-9]_23 chr1:65469938-65470438 3.2e-06 39_[-9]_50 chr6:3911802-3912302 3.9e-06 23_[-9]_66 chr1:167658543-167659043 3.9e-06 88_[-9]_1 chr21:29217762-29218262 4.4e-06 81_[-9]_8 chr10:124323112-12432361 5.1e-06 71_[+9]_18 chr17:78624707-78625207 5.9e-06 57_[-9]_32 chr17:60173295-60173795 7e-06 76_[+9]_13 chr15:58038593-58039093 8.6e-06 33_[-9]_56 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTTTACARAR width=11 seqs=21 chr20:53609871-53610371 ( 40) TGTTTACAAAA 1 chr3:138833396-138833896 ( 62) TGTTTACAAAA 1 chr3:14452053-14452553 ( 38) TGTTTACAGAG 1 chr17:57569837-57570337 ( 55) TGTTTACAGAG 1 chr22:23218718-23219218 ( 32) TGTTTACAGAG 1 chr7:157880964-157881464 ( 49) TGTTTACAGTA 1 chr3:16482916-16483416 ( 34) TATTTACAGAG 1 chr22:40711447-40711947 ( 42) TATTTACAGAG 1 chr1:224615791-224616291 ( 46) TGTTTAAAGAG 1 chr10:87845976-87846476 ( 9) TGTTGACAGAA 1 chr6:33758745-33759245 ( 34) TGTTTACATTA 1 chr1:86774478-86774978 ( 18) TGTTTACCAAA 1 chr6:6678172-6678672 ( 67) TGTTTACCAAA 1 chr1:65469938-65470438 ( 40) TGTTTAAAATA 1 chr6:3911802-3912302 ( 24) TGTTTAAAGTG 1 chr1:167658543-167659043 ( 89) TGTTTACAGCA 1 chr21:29217762-29218262 ( 82) TGTTGACAAAG 1 chr10:124323112-12432361 ( 72) TGTTTACAAGA 1 chr17:78624707-78625207 ( 58) TATTTACATAG 1 chr17:60173295-60173795 ( 77) TGTCTACAGAG 1 chr15:58038593-58039093 ( 34) AGTTTACAGTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 11 n= 54000 bayes= 12.3144 E= 2.7e+001 -219 -1104 -1104 213 -61 -1104 160 -1104 -1104 -1104 -1104 220 -1104 -256 -1104 213 -1104 -1104 -156 205 220 -1104 -1104 -1104 -61 160 -1104 -1104 205 -156 -1104 -1104 61 -1104 102 -119 161 -256 -256 13 126 -1104 76 -1104 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 11 nsites= 21 E= 2.7e+001 0.047619 0.000000 0.000000 0.952381 0.142857 0.000000 0.857143 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.047619 0.000000 0.952381 0.000000 0.000000 0.095238 0.904762 1.000000 0.000000 0.000000 0.000000 0.142857 0.857143 0.000000 0.000000 0.904762 0.095238 0.000000 0.000000 0.333333 0.000000 0.571429 0.095238 0.666667 0.047619 0.047619 0.238095 0.523810 0.000000 0.476190 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTTTACARAR MEME-9 regular expression -------------------------------------------------------------------------------- TGTTTACA[GA][AT][AG] -------------------------------------------------------------------------------- Time 4061.02 secs. ******************************************************************************** ******************************************************************************** MOTIF GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 width = 42 sites = 3 llr = 142 E-value = 2.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 Description -------------------------------------------------------------------------------- Simplified A :3:7::::::7:a:7a7:::7::::::a:a:7:7:a:a:7:: pos.-specific C :::3:aa::a3::a:::7a73aaa:a3:a:::73a:a:::3a probability G a7a:a:::a::7::::33:3::::::7:::a:3:::::a:7: matrix T :::::::a:::3::3:::::::::a::::::3:::::::3:: bits 2.2 * * * * * * * * 2.0 * * * * * * * * 1.8 * * ****** ** * * ***** **** ***** * 1.5 * * ****** ** * * ***** **** ***** * Relative 1.3 * * ****** **** * ***** ***** ****** * Entropy 1.1 ***************** * ****** ***** ******* * (68.5 bits) 0.9 ****************************************** 0.7 ****************************************** 0.4 ****************************************** 0.2 ****************************************** 0.0 ------------------------------------------ Multilevel GGGAGCCTGCAGACAAACCCACCCTCGACAGACACACAGAGC consensus A C CT T GG GC C TGC TC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Strand Start P-value Site ------------- ------ ----- --------- ------------------------------------------ chr17:83026563-83027063 + 12 1.32e-25 GAGGAGGGCG GGGAGCCTGCAGACAAACCCACCCTCGACAGACACACAGAGC AGGGCGGGGA chr17:83026765-83027265 + 2 1.32e-25 A GGGAGCCTGCAGACAAACCCACCCTCGACAGACACACAGAGC GGGGCAGGGA chr19:36054118-36054618 + 46 9.88e-20 AGAGAGCTGA GAGCGCCTGCCTACTAGGCGCCCCTCCACAGTGCCACAGTCC CGCCCTCGTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:83026563-83027063 1.3e-25 11_[+10]_47 chr17:83026765-83027265 1.3e-25 1_[+10]_57 chr19:36054118-36054618 9.9e-20 45_[+10]_13 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC width=42 seqs=3 chr17:83026563-83027063 ( 12) GGGAGCCTGCAGACAAACCCACCCTCGACAGACACACAGAGC 1 chr17:83026765-83027265 ( 2) GGGAGCCTGCAGACAAACCCACCCTCGACAGACACACAGAGC 1 chr19:36054118-36054618 ( 46) GAGCGCCTGCCTACTAGGCGCCCCTCCACAGTGCCACAGTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 42 n= 35400 bayes= 13.9739 E= 2.2e+003 -823 -823 182 -823 61 -823 124 -823 -823 -823 182 -823 161 24 -823 -823 -823 -823 182 -823 -823 182 -823 -823 -823 182 -823 -823 -823 -823 -823 219 -823 -823 182 -823 -823 182 -823 -823 161 24 -823 -823 -823 -823 124 61 219 -823 -823 -823 -823 182 -823 -823 161 -823 -823 61 219 -823 -823 -823 161 -823 24 -823 -823 124 24 -823 -823 182 -823 -823 -823 124 24 -823 161 24 -823 -823 -823 182 -823 -823 -823 182 -823 -823 -823 182 -823 -823 -823 -823 -823 219 -823 182 -823 -823 -823 24 124 -823 219 -823 -823 -823 -823 182 -823 -823 219 -823 -823 -823 -823 -823 182 -823 161 -823 -823 61 -823 124 24 -823 161 24 -823 -823 -823 182 -823 -823 219 -823 -823 -823 -823 182 -823 -823 219 -823 -823 -823 -823 -823 182 -823 161 -823 -823 61 -823 24 124 -823 -823 182 -823 -823 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 42 nsites= 3 E= 2.2e+003 0.000000 0.000000 1.000000 0.000000 0.333333 0.000000 0.666667 0.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.333333 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.666667 0.333333 0.000000 0.000000 0.000000 0.000000 0.666667 0.333333 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.333333 1.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.333333 0.000000 0.000000 0.666667 0.333333 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.666667 0.333333 0.000000 0.666667 0.333333 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.333333 0.666667 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.000000 0.000000 0.333333 0.000000 0.666667 0.333333 0.000000 0.666667 0.333333 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.000000 0.000000 0.333333 0.000000 0.333333 0.666667 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGMGCCTGCMKACWARSCSMCCCTCSACAGWSMCACAGWSC MEME-10 regular expression -------------------------------------------------------------------------------- G[GA]G[AC]GCCTGC[AC][GT]AC[AT]A[AG][CG]C[CG][AC]CCCTC[GC]ACAG[AT][CG][AC]CACAG[AT][GC]C -------------------------------------------------------------------------------- Time 4471.23 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:57849943-57850443 9.76e-01 100 chr7:151727580-151728080 1.80e-02 28_[+5(8.29e-06)]_60 chr17:7234314-7234814 2.90e-01 100 chr14:99274599-99275099 7.35e-01 100 chr11:70146805-70147305 7.03e-01 100 chr5:142215852-142216352 2.78e-02 47_[+6(1.85e-05)]_41 chr1:151988332-151988832 1.44e-02 79_[+3(5.06e-05)]_14 chr10:121613407-12161390 4.53e-01 7_[-2(2.99e-05)]_24_[-2(8.03e-05)]_\ 37 chr4:105708479-105708979 6.83e-01 100 chr17:68019693-68020193 1.51e-01 100 chr11:64854878-64855378 9.27e-03 21_[-2(3.98e-05)]_8_[+3(5.06e-05)]_\ 48 chr2:3296206-3296706 4.29e-07 51_[+1(1.13e-07)]_19 chr10:73879563-73880063 1.90e-01 100 chr17:51703409-51703909 4.01e-02 44_[+8(8.60e-07)]_44 chr12:123232750-12323325 7.75e-02 12_[+1(7.24e-06)]_58 chr5:139341704-139342204 8.27e-01 100 chr1:205211479-205211979 2.39e-01 100 chr1:233112858-233113358 8.65e-02 60_[-5(5.33e-06)]_28 chr12:132161304-13216180 1.50e-01 74_[-2(8.03e-05)]_10 chr1:156114113-156114613 1.00e-01 65_[-2(4.96e-06)]_19 chr17:15999373-15999873 8.14e-01 34_[-7(9.28e-05)]_44 chr13:41696486-41696986 5.64e-02 12_[-5(2.99e-05)]_76 chr10:35195645-35196145 3.67e-02 100 chr10:129605954-12960645 1.92e-01 100 chr4:4541841-4542341 7.03e-01 100 chr15:71279100-71279600 5.99e-02 100 chr5:174503838-174504338 6.64e-08 37_[+2(1.30e-05)]_14_[-1(8.68e-07)]_\ 3 chr1:47577925-47578425 4.01e-02 41_[+8(9.21e-06)]_47 chr1:32817145-32817645 1.87e-01 61_[+2(1.45e-05)]_23 chr14:104677696-10467819 6.83e-02 21_[-3(5.06e-05)]_72 chr22:50381127-50381627 6.78e-01 100 chr22:38606557-38607057 6.02e-03 32_[-8(9.89e-05)]_[+6(2.40e-05)]_44 chr1:3415477-3415977 3.74e-01 100 chr7:28729212-28729712 3.02e-08 35_[-1(3.42e-08)]_6_[-2(2.18e-06)]_\ 13 chr10:102399387-10239988 9.93e-01 100 chr19:46600804-46601304 7.90e-01 100 chr19:41310146-41310646 5.16e-01 100 chr9:33415469-33415969 3.06e-01 100 chr17:51046593-51047093 1.35e-03 23_[-5(1.41e-06)]_[-2(5.23e-05)]_49 chr1:9943162-9943662 9.18e-01 100 chr15:95556832-95557332 5.51e-03 33_[+6(3.87e-05)]_55 chr3:50268839-50269339 8.22e-01 100 chr3:194139139-194139639 9.49e-01 100 chr6:47134654-47135154 4.51e-03 5_[-3(5.06e-05)]_59_[+8(8.30e-05)]_\ 17 chr15:64387538-64388038 9.24e-01 100 chr17:3679850-3680350 9.11e-04 7_[+4(8.61e-08)]_5_[-2(2.52e-06)]_\ 29 chr9:108543257-108543757 1.16e-02 69_[-6(3.22e-06)]_19 chr3:4320401-4320901 1.08e-04 17_[-9(4.12e-06)]_7_[-8(9.89e-07)]_\ 53 chr19:11094950-11095450 4.54e-02 62_[+3(5.06e-05)]_31 chr6:158040319-158040819 1.00e-04 14_[-6(1.53e-06)]_40_[-3(5.06e-05)]_\ 27 chr12:2812733-2813233 4.69e-02 100 chr10:72354671-72355171 2.21e-01 43_[+2(1.45e-05)]_41 chr19:40603612-40604112 3.07e-01 100 chr6:125812676-125813176 1.52e-03 9_[-3(5.06e-05)]_37_[-2(8.03e-05)]_\ 2_[-9(5.13e-05)]_18 chr17:82494508-82495008 9.83e-01 100 chr17:4949582-4950082 2.39e-01 71_[+3(5.06e-05)]_22 chr1:223726517-223727017 4.85e-02 [+2(3.81e-06)]_19_[-2(3.62e-05)]_49 chr3:194322630-194323130 5.17e-03 31_[-8(2.72e-05)]_4_[+3(5.06e-05)]_\ 46 chr12:6765974-6766474 9.39e-03 1_[-2(1.16e-05)]_8_[+4(2.06e-05)]_\ 13_[-2(1.39e-06)]_3 chr3:14879341-14879841 2.35e-02 100 chr1:167658543-167659043 2.41e-03 58_[+6(2.41e-06)]_18_[-9(3.87e-06)]_\ 1 chr12:132828748-13282924 5.76e-01 100 chr12:113245733-11324623 1.84e-01 88_[-5(9.55e-06)] chr3:194089490-194089990 2.96e-01 25_[-8(8.30e-05)]_63 chr8:22678252-22678752 5.35e-03 10_[-3(5.06e-05)]_83 chr19:35931472-35931972 9.98e-01 100 chr1:202018498-202018998 7.43e-01 100 chr1:223707103-223707603 1.35e-01 56_[-3(5.06e-05)]_20_[-3(5.06e-05)]_\ 10 chr21:43733511-43734011 2.78e-01 100 chr10:17201416-17201916 2.82e-02 69_[-2(6.42e-08)]_15 chr1:151070351-151070851 7.15e-02 16_[-9(8.37e-05)]_73 chr6:87155229-87155729 1.41e-01 16_[-2(8.72e-05)]_68 chr1:227946203-227946703 3.22e-03 25_[+3(5.06e-05)]_11_[-2(5.63e-06)]_\ 41 chr15:75711516-75712016 1.52e-01 100 chr1:31937335-31937835 2.92e-07 8_[+1(1.51e-07)]_4_[-2(2.99e-05)]_\ 12_[+1(4.62e-05)] chr16:4316758-4317258 7.98e-01 100 chr19:55338664-55339164 6.06e-05 53_[+1(3.47e-07)]_17 chr19:17680083-17680583 5.92e-02 100 chr22:35894887-35895387 4.02e-03 3_[-2(3.33e-06)]_54_[+6(2.63e-05)]_\ 15 chr15:82040828-82041328 3.19e-01 100 chr5:10307555-10308055 1.46e-01 39_[-4(2.34e-05)]_18 chr22:46773775-46774275 6.42e-04 19_[+9(3.70e-05)]_13_[-3(5.06e-05)]_\ 7_[-10(2.02e-05)]_1 chr10:75379161-75379661 3.81e-04 26_[+5(5.32e-05)]_20_[+8(7.95e-07)]_\ 30 chr19:11018117-11018617 2.79e-03 15_[-3(5.06e-05)]_29_[-2(6.38e-06)]_\ 33 chr21:45353077-45353577 1.60e-05 58_[-1(1.74e-07)]_12 chr10:126199173-12619967 9.22e-02 16_[+3(5.06e-05)]_42_[-3(5.06e-05)]_\ 28 chr5:94469755-94470255 2.99e-03 1_[-8(2.43e-07)]_87 chr18:26468980-26469480 4.63e-02 82_[+8(1.19e-05)]_6 chr17:44014754-44015254 5.12e-01 81_[+6(9.22e-05)]_7 chr1:41783139-41783639 6.16e-05 16_[-7(2.56e-06)]_62 chr5:124655948-124656448 1.07e-02 11_[-6(2.03e-05)]_77 chr18:63457939-63458439 5.86e-02 44_[-8(2.27e-05)]_44 chr7:27165486-27165986 1.72e-01 100 chr17:75124208-75124708 2.19e-02 38_[-3(5.06e-05)]_12_[-3(5.06e-05)]_\ 36 chr3:4741599-4742099 3.45e-03 58_[+3(5.06e-05)]_9_[+6(5.58e-05)]_\ 14 chr12:56041724-56042224 8.32e-02 46_[-6(3.07e-07)]_42 chr12:131128958-13112945 6.78e-02 52_[+7(4.40e-07)]_26 chr22:45934591-45935091 3.80e-02 7_[+8(6.28e-06)]_81 chr1:42165880-42166380 1.35e-24 35_[-1(6.77e-19)]_3_[-1(9.79e-08)]_\ 2 chr10:42782490-42782990 1.82e-02 66_[+7(9.25e-07)]_12 chr12:89352479-89352979 2.65e-03 21_[+2(1.16e-05)]_29_[-8(3.91e-05)]_\ 22 chr10:113063305-11306380 2.15e-03 3_[+2(1.18e-06)]_10_[-4(1.37e-05)]_\ 28 chr5:125485067-125485567 1.64e-04 42_[-3(5.06e-05)]_10_[+6(7.14e-06)]_\ 29 chr1:45521618-45522118 4.67e-01 100 chr9:33159207-33159707 1.15e-01 100 chr22:32539579-32540079 7.24e-06 13_[-6(2.41e-06)]_38_[+2(3.62e-05)]_\ 1_[-5(1.21e-05)]_8 chr7:157880964-157881464 3.33e-07 16_[-5(6.55e-06)]_20_[+9(5.80e-07)]_\ 13_[-5(6.55e-06)]_16 chr16:30052839-30053339 3.57e-01 9_[+2(4.78e-05)]_75 chr16:22189995-22190495 9.95e-01 100 chr21:43307000-43307500 9.47e-02 30_[+3(5.06e-05)]_15_[+3(5.06e-05)]_\ 41 chr1:228838378-228838878 1.65e-03 17_[-5(5.32e-05)]_6_[-3(5.06e-05)]_\ 58 chr10:94673534-94674034 2.24e-02 [+5(1.19e-06)]_24_[+5(9.55e-06)]_3_\ [+5(2.71e-06)]_24_[+5(1.36e-05)]_1 chr8:37329665-37330165 1.12e-03 20_[+6(8.66e-05)]_20_[+8(3.66e-06)]_\ 36 chr17:48577409-48577909 7.80e-02 19_[+2(5.23e-05)]_65 chr22:23218718-23219218 7.81e-03 31_[+9(3.51e-07)]_58 chr1:228647614-228648114 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25_[+6(9.85e-07)]_63 chr12:48021664-48022164 3.60e-07 31_[+1(4.43e-09)]_39 chr17:51153296-51153796 2.47e-01 100 chr16:30957582-30958082 1.00e+00 100 chr12:131627238-13162773 2.23e-01 3_[-2(2.71e-05)]_18_[-2(2.71e-05)]_\ 18_[-2(2.71e-05)]_13 chr21:34845654-34846154 9.63e-02 44_[+3(5.06e-05)]_49 chr1:1000656-1001156 3.08e-01 15_[+5(9.55e-06)]_32_[-5(1.78e-06)]_\ 29 chr1:156586937-156587437 2.29e-01 54_[-2(4.37e-05)]_14_[-2(4.37e-05)] chr10:121310152-12131065 2.55e-01 56_[+8(5.88e-05)]_32 chr21:39313503-39314003 9.71e-01 100 chr10:71218031-71218531 6.88e-10 30_[-1(4.99e-10)]_40 chr1:3403735-3404235 1.02e-05 67_[+1(9.25e-07)]_3 chr17:74514127-74514627 1.49e-01 11_[-5(1.78e-06)]_20_[-5(1.78e-06)]_\ 5_[-5(1.78e-06)]_28 chr12:12266922-12267422 4.52e-01 100 chr19:35628752-35629252 1.62e-02 57_[-5(3.64e-06)]_31 chr13:110870184-11087068 4.97e-01 15_[-3(5.06e-05)]_78 chr1:3352955-3353455 6.98e-01 100 chr16:4944709-4945209 9.63e-02 57_[+3(5.06e-05)]_15_[+3(5.06e-05)]_\ 14 chr3:195907748-195908248 8.64e-01 100 chr1:229064400-229064900 5.24e-04 53_[+6(3.12e-05)]_35 chr19:35248581-35249081 1.39e-01 75_[-8(2.51e-05)]_13 chr20:58650937-58651437 2.88e-01 100 chr17:49976145-49976645 3.73e-01 83_[-8(9.16e-05)]_5 chr12:54359089-54359589 1.40e-02 77_[+2(6.79e-05)]_7 chr17:42998034-42998534 2.70e-01 48_[+4(8.29e-06)]_9 chr12:131627008-13162750 3.12e-01 58_[-2(5.72e-05)]_26 chr12:132445991-13244649 1.50e-02 19_[+5(6.98e-08)]_39_[+5(6.98e-08)]_\ 18 chr3:11140207-11140707 1.24e-04 23_[-7(7.96e-06)]_55 chr1:183471788-183472288 3.57e-02 38_[-4(5.09e-06)]_19 chr3:14452053-14452553 2.86e-05 5_[+5(1.83e-05)]_20_[-9(3.51e-07)]_\ 18_[-3(5.06e-05)]_27 chr15:70091903-70092403 1.41e-01 31_[-8(9.21e-06)]_57 chr1:236097023-236097523 5.90e-01 12_[-3(5.06e-05)]_22_[-3(5.06e-05)]_\ 22_[-3(5.06e-05)]_23 chr8:37302611-37303111 2.13e-01 100 chr5:10551208-10551708 4.40e-01 100 chr9:85743161-85743661 2.24e-02 15_[-6(2.88e-05)]_73 chr10:77287672-77288172 6.36e-02 100 chr1:41870087-41870587 5.31e-04 3_[+3(5.06e-05)]_33_[+3(5.06e-05)]_\ 11_[-2(8.72e-05)]_10_[-6(3.61e-05)]_1 chr3:9731327-9731827 2.94e-01 40_[-5(1.83e-05)]_48 chr1:31431809-31432309 2.67e-01 7_[+2(8.72e-05)]_2_[+2(8.72e-05)]_2_\ [+2(8.72e-05)]_20_[+2(8.72e-05)]_5 chr1:153566438-153566938 1.50e-01 55_[-3(5.06e-05)]_31_[-3(5.06e-05)] chr5:124740931-124741431 2.62e-02 34_[+2(4.78e-05)]_21_[-8(9.16e-05)]_\ 17 chr16:324364-324864 4.95e-02 100 chr17:83026563-83027063 9.55e-16 11_[+10(1.32e-25)]_47 chr5:137516434-137516934 2.10e-01 16_[+2(3.62e-05)]_18_[+2(3.62e-05)]_\ 15_[+2(3.62e-05)]_3 chr19:1652602-1653102 3.98e-01 100 chr19:40831828-40832328 2.10e-01 100 chr13:110965219-11096571 4.55e-17 10_[+4(3.17e-19)]_2_[+4(8.96e-20)]_\ 2 chr16:15590866-15591366 1.78e-03 30_[-6(6.36e-06)]_8_[+3(5.06e-05)]_\ 43 chr2:10014220-10014720 8.35e-09 1_[-1(2.86e-09)]_40_[+7(4.46e-05)]_\ 7 chr1:3992028-3992528 3.20e-02 15_[-5(5.33e-06)]_5_[-5(1.78e-06)]_\ 4_[-5(1.78e-06)]_4_[-5(1.78e-06)]_4_[-5(1.78e-06)]_8 chr17:7836699-7837199 1.11e-01 74_[-2(1.61e-05)]_10 chr20:64030487-64030987 8.16e-02 54_[-8(6.25e-05)]_34 chr1:12478120-12478620 1.63e-01 100 chr11:27796253-27796753 2.42e-02 4_[+2(4.37e-05)]_80 chr12:124914541-12491504 4.41e-01 100 chr19:40920964-40921464 4.51e-03 32_[+3(5.06e-05)]_61 chr1:223023039-223023539 2.27e-01 100 chr20:32561324-32561824 6.47e-01 100 chrX:70220297-70220797 5.70e-03 38_[-2(4.78e-05)]_46 chr1:234723925-234724425 1.89e-04 13_[+2(6.42e-08)]_13_[+2(3.81e-06)]_\ 42 chr8:630791-631291 3.14e-03 26_[-3(5.06e-05)]_39_[-3(5.06e-05)]_\ 21 chr2:120515323-120515823 1.09e-04 15_[-2(7.20e-07)]_1_[-2(8.56e-07)]_\ 18_[-2(1.01e-06)]_18 chr3:194134814-194135314 1.05e-10 30_[+1(3.26e-12)]_40 chr3:16482916-16483416 7.29e-06 33_[+9(1.56e-06)]_9_[-8(3.66e-06)]_\ 8_[-6(7.88e-07)]_15 chr16:12120422-12120922 3.48e-08 9_[+7(6.32e-08)]_3_[-1(2.40e-09)]_\ 36 chr1:155244578-155245078 3.95e-02 9_[+2(1.16e-05)]_46_[+2(3.33e-06)]_\ 13 chr1:208184303-208184803 6.72e-03 30_[+2(1.99e-05)]_54 chr19:1394296-1394796 1.23e-02 14_[-2(3.59e-09)]_11_[-2(3.33e-06)]_\ 7_[-2(3.33e-06)]_20 chr20:16257770-16258270 1.92e-07 8_[-6(3.37e-05)]_18_[+1(8.72e-09)]_\ 32 chr1:31387527-31388027 6.44e-07 13_[+1(4.43e-09)]_6_[+1(4.30e-08)]_\ 21 chr20:63723002-63723502 2.31e-03 [-2(2.89e-06)]_12_[-2(2.89e-06)]_12_\ [-2(2.89e-06)]_12_[-2(2.89e-06)] chr19:43572061-43572561 1.82e-09 5_[-6(4.12e-06)]_13_[+1(1.74e-07)]_\ 8_[+5(5.80e-06)]_20 chr6:168147170-168147670 5.34e-03 77_[-6(2.03e-05)]_11 chr3:4986798-4987298 9.99e-01 100 chr17:60173295-60173795 6.02e-03 19_[-9(2.02e-05)]_8_[-5(2.50e-05)]_\ 26_[+9(6.99e-06)]_13 chr15:25758486-25758986 9.57e-18 2_[-2(2.18e-06)]_12_[-2(5.07e-07)]_\ 2_[+4(1.14e-22)]_9 chr7:155205298-155205798 9.23e-01 100 chr1:16122832-16123332 4.38e-01 100 chr10:3314556-3315056 4.93e-03 5_[+2(4.35e-06)]_13_[+2(4.35e-06)]_\ 13_[+2(3.98e-05)]_21 chr1:31431607-31432107 2.99e-01 8_[-1(8.63e-05)]_27_[+2(8.72e-05)]_\ 19 chr17:3890048-3890548 5.51e-01 89_[-3(5.06e-05)]_4 chr1:43423542-43424042 3.66e-02 26_[-4(4.13e-05)]_31 chr17:78558298-78558798 1.64e-02 13_[+5(1.19e-06)]_10_[-5(1.78e-06)]_\ 10_[-5(4.08e-06)]_16_[-5(1.49e-05)]_3 chr5:1950676-1951176 3.51e-03 16_[-1(3.71e-07)]_54 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (10) found. ******************************************************************************** CPU: kali ********************************************************************************