In [1]:
# Parameters
data_name = "Tbx5"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:42:08,392 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Tbx5: Motif: M09649_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Tbx5: #2

Cell typeModiscoHomer
T_LCMV;CD8+;D8;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.027467400000000003

Pattern: motif19.motif

Significance: 0.055014099999999996

NK_SPLND;A;CL

Pattern: metacluster_0/pattern_15

Significance: 0.0104241

Pattern: motif14.motif

Significance: 0.028489599999999997

Unique Cell types only TF-MoDISco finds Tbx5: #3

Cell typeModiscoHomer
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 0.0497671

Absent
TEff_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0161958

Absent
ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0408288

Absent
Unique Cell types only Homer finds Tbx5: #6

Cell typeModiscoHomer
NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.00728895

LNG;P0;D;EnAbsent

Pattern: motif18.motif

Significance: 0.0567991

plasmaB;A;CLAbsent

Pattern: motif9.motif

Significance: 0.0211859

G_NRN_P;A;GEOAbsent

Pattern: motif5.motif

Significance: 0.0337016

ThMS_MEC;Aire++;A;GEOAbsent

Pattern: motif12.motif

Significance: 0.050784699999999995

wES;5th_Rhmbmr;E9.5;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.051204099999999995